BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239745895 PREDICTED: hypothetical protein XP_002343612 [Homo sapiens] (404 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239751388 PREDICTED: hypothetical protein XP_002347834 [Homo ... 850 0.0 gi|239745895 PREDICTED: hypothetical protein XP_002343612 [Homo ... 850 0.0 gi|239756892 PREDICTED: hypothetical protein [Homo sapiens] 788 0.0 gi|48762934 alpha 2 type I collagen [Homo sapiens] 49 1e-05 gi|209915594 transcription factor 3 isoform E47 [Homo sapiens] 48 2e-05 gi|27777636 transcription factor 3 isoform E12 [Homo sapiens] 47 2e-05 gi|60097902 filaggrin [Homo sapiens] 46 5e-05 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 46 5e-05 gi|239751449 PREDICTED: hypothetical protein XP_002347867 [Homo ... 46 5e-05 gi|239745954 PREDICTED: hypothetical protein XP_002343623 [Homo ... 46 5e-05 gi|239756937 PREDICTED: hypothetical protein [Homo sapiens] 46 7e-05 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 45 9e-05 gi|13489073 egl nine homolog 1 [Homo sapiens] 45 1e-04 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 45 2e-04 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 44 2e-04 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 44 2e-04 gi|197333868 T-box 2 [Homo sapiens] 44 2e-04 gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 43 4e-04 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 43 6e-04 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 43 6e-04 gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens] 42 0.001 gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 42 0.001 gi|50843837 hypothetical protein LOC55701 [Homo sapiens] 42 0.001 gi|169168886 PREDICTED: hypothetical protein [Homo sapiens] 41 0.002 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 41 0.002 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 41 0.002 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 41 0.002 gi|23397672 homeobox D4 [Homo sapiens] 40 0.003 gi|239751026 PREDICTED: hypothetical protein XP_002347678 [Homo ... 40 0.003 gi|239745455 PREDICTED: hypothetical protein XP_002343496 [Homo ... 40 0.003 >gi|239751388 PREDICTED: hypothetical protein XP_002347834 [Homo sapiens] Length = 404 Score = 850 bits (2197), Expect = 0.0 Identities = 404/404 (100%), Positives = 404/404 (100%) Query: 1 MLQNPYAAINTEELVKKGESGQSGIGSVGRASQKTARRGKRKTNMLGVGIQICAPNLMWK 60 MLQNPYAAINTEELVKKGESGQSGIGSVGRASQKTARRGKRKTNMLGVGIQICAPNLMWK Sbjct: 1 MLQNPYAAINTEELVKKGESGQSGIGSVGRASQKTARRGKRKTNMLGVGIQICAPNLMWK 60 Query: 61 IHSLPYAKGGAPHWNSEFQTKAKEIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAGGQ 120 IHSLPYAKGGAPHWNSEFQTKAKEIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAGGQ Sbjct: 61 IHSLPYAKGGAPHWNSEFQTKAKEIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAGGQ 120 Query: 121 VAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFRGSEMNSESRR 180 VAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFRGSEMNSESRR Sbjct: 121 VAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFRGSEMNSESRR 180 Query: 181 GQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDE 240 GQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDE Sbjct: 181 GQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDE 240 Query: 241 GALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTR 300 GALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTR Sbjct: 241 GALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTR 300 Query: 301 RNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLS 360 RNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLS Sbjct: 301 RNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLS 360 Query: 361 TSRDPKSSYTHTHTHTHTEPAPVLEFSTPVKAICCFHHPPEHRH 404 TSRDPKSSYTHTHTHTHTEPAPVLEFSTPVKAICCFHHPPEHRH Sbjct: 361 TSRDPKSSYTHTHTHTHTEPAPVLEFSTPVKAICCFHHPPEHRH 404 >gi|239745895 PREDICTED: hypothetical protein XP_002343612 [Homo sapiens] Length = 404 Score = 850 bits (2197), Expect = 0.0 Identities = 404/404 (100%), Positives = 404/404 (100%) Query: 1 MLQNPYAAINTEELVKKGESGQSGIGSVGRASQKTARRGKRKTNMLGVGIQICAPNLMWK 60 MLQNPYAAINTEELVKKGESGQSGIGSVGRASQKTARRGKRKTNMLGVGIQICAPNLMWK Sbjct: 1 MLQNPYAAINTEELVKKGESGQSGIGSVGRASQKTARRGKRKTNMLGVGIQICAPNLMWK 60 Query: 61 IHSLPYAKGGAPHWNSEFQTKAKEIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAGGQ 120 IHSLPYAKGGAPHWNSEFQTKAKEIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAGGQ Sbjct: 61 IHSLPYAKGGAPHWNSEFQTKAKEIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAGGQ 120 Query: 121 VAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFRGSEMNSESRR 180 VAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFRGSEMNSESRR Sbjct: 121 VAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFRGSEMNSESRR 180 Query: 181 GQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDE 240 GQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDE Sbjct: 181 GQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDE 240 Query: 241 GALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTR 300 GALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTR Sbjct: 241 GALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTR 300 Query: 301 RNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLS 360 RNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLS Sbjct: 301 RNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLS 360 Query: 361 TSRDPKSSYTHTHTHTHTEPAPVLEFSTPVKAICCFHHPPEHRH 404 TSRDPKSSYTHTHTHTHTEPAPVLEFSTPVKAICCFHHPPEHRH Sbjct: 361 TSRDPKSSYTHTHTHTHTEPAPVLEFSTPVKAICCFHHPPEHRH 404 >gi|239756892 PREDICTED: hypothetical protein [Homo sapiens] Length = 576 Score = 788 bits (2034), Expect = 0.0 Identities = 377/378 (99%), Positives = 377/378 (99%) Query: 1 MLQNPYAAINTEELVKKGESGQSGIGSVGRASQKTARRGKRKTNMLGVGIQICAPNLMWK 60 MLQNPYAAINTEELVKKGESGQSGIGSVGRASQKTARRGKRKTNMLGVGIQICAPNLMWK Sbjct: 1 MLQNPYAAINTEELVKKGESGQSGIGSVGRASQKTARRGKRKTNMLGVGIQICAPNLMWK 60 Query: 61 IHSLPYAKGGAPHWNSEFQTKAKEIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAGGQ 120 I SLPYAKGGAPHWNSEFQTKAKEIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAGGQ Sbjct: 61 IQSLPYAKGGAPHWNSEFQTKAKEIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAGGQ 120 Query: 121 VAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFRGSEMNSESRR 180 VAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFRGSEMNSESRR Sbjct: 121 VAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFRGSEMNSESRR 180 Query: 181 GQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDE 240 GQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDE Sbjct: 181 GQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDE 240 Query: 241 GALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTR 300 GALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTR Sbjct: 241 GALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTR 300 Query: 301 RNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLS 360 RNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLS Sbjct: 301 RNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLS 360 Query: 361 TSRDPKSSYTHTHTHTHT 378 TSRDPKSSYTHTHTHTHT Sbjct: 361 TSRDPKSSYTHTHTHTHT 378 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 48.5 bits (114), Expect = 1e-05 Identities = 71/268 (26%), Positives = 92/268 (34%), Gaps = 44/268 (16%) Query: 114 PPAAGGQVAARGKEPKPG-----GRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKG 168 PP GQ +G+ PG G P H P G H +G GPS A G Sbjct: 935 PPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVG 994 Query: 169 FRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQ 228 RG + RG EK PR +G G + GH Sbjct: 995 PRGPS-GPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHH--------------- 1038 Query: 229 AALHAVRLDGDEGALQVGHGPAG-RELEGPGGGAAL-GEQRAGATTTPGSRRRRRGAGRS 286 GD+GA GPAG R GP G A G T P R +G Sbjct: 1039 ---------GDQGA-PGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGP 1088 Query: 287 AGWPHPGGPSRPTRRNAPPARPDAAGE----QCPRPA-GARPRQAEIETDPETGSDSFST 341 AG P P GP P + G+ PR A RP+ E++ ++ ++ T Sbjct: 1089 AGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPKDYEVDATLKSLNNQIET 1148 Query: 342 WTSYEFNYARPKSHSSPLSTSRDPKSSY 369 + E S +P T RD + S+ Sbjct: 1149 LLTPE------GSRKNPARTCRDLRLSH 1170 Score = 38.5 bits (88), Expect = 0.011 Identities = 66/233 (28%), Positives = 78/233 (33%), Gaps = 38/233 (16%) Query: 96 RVGRRRGSGARGFSAPCCPPAAGGQVAAR------GKEPKPGGRVTLPALHLPKGVCPHH 149 R G +G G P PP GG AA+ G P P G L P+G Sbjct: 52 RDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMG------LMGPRGP---- 101 Query: 150 PGKGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTA----AGREKHPRAGCSGE-GETGAS 204 PG A + +G + + RG AG + HP G G GE G Sbjct: 102 PGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHP--GKPGRPGERGVV 159 Query: 205 YPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALG 264 P+ G L H LDG +G Q G E PG G Sbjct: 160 GPQGARGFPGTPGLPGFKGIRGHNG------LDGLKG--QPGAPGVKGEPGAPGENGTPG 211 Query: 265 EQRAGATTTPGSRRR-----RRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAG 312 + GA PG R R GA S G P GP+ P PP P A G Sbjct: 212 Q--TGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPG 262 Score = 34.7 bits (78), Expect = 0.16 Identities = 68/234 (29%), Positives = 82/234 (35%), Gaps = 33/234 (14%) Query: 98 GRRRGSGARGFSAPCCPPAAG--GQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSA 155 G+ G +G P P G GQ ARG P GRV P P G G Sbjct: 190 GQPGAPGVKG--EPGAPGENGTPGQTGARGL-PGERGRVGAPG---PAGARGSDGSVGPV 243 Query: 156 GPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPR--AGCSGE-GETGASYPEELHGH 212 GP+ GF G+ +G+ A P AG GE G G S P G+ Sbjct: 244 GPAGPIGSAGPPGFPGAP----GPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGN 299 Query: 213 EAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRA--GA 270 + L A A L G GA + P R + GP G A R G Sbjct: 300 PGANGLT---------GAKGAAGLPGVAGAPGL---PGPRGIPGPVGAAGATGARGLVGE 347 Query: 271 TTTPGSRRR--RRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGAR 322 GS+ +G SAG P GPS + P +AG P P G R Sbjct: 348 PGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGP--PGPPGLR 399 Score = 33.1 bits (74), Expect = 0.46 Identities = 68/258 (26%), Positives = 80/258 (31%), Gaps = 30/258 (11%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKE--------PKPGGRVTLPALHLPKGVCPHH 149 G R G GF P P G+ +G P P G P+GV Sbjct: 484 GARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGV---Q 540 Query: 150 PGKGSAGPSRRGRGQRAKGFRG--SEMNSESRRGQTAAGREKHPRAGCSGE----GETGA 203 GKG GP Q G G E+ RG P AG GE GE+GA Sbjct: 541 GGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGP-AGPRGERGPPGESGA 599 Query: 204 SYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEG-PGGGAA 262 + P G S + + AV G G + P R G PGG Sbjct: 600 AGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGL---PGERGAAGIPGGKGE 656 Query: 263 LGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGAR 322 GE PG R GR PG P A R +A PAG R Sbjct: 657 KGE--------PGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPR 708 Query: 323 PRQAEIETDPETGSDSFS 340 E G + F+ Sbjct: 709 GSPGERGEVGPAGPNGFA 726 Score = 32.7 bits (73), Expect = 0.60 Identities = 52/231 (22%), Positives = 71/231 (30%), Gaps = 20/231 (8%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPGK--- 152 G R G G + PP G +G++ PG G LP P G PG+ Sbjct: 517 GARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGK-PGERGL 575 Query: 153 -------GSAGP--SRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGA 203 G AGP R G+ + S G K G G Sbjct: 576 HGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGP 635 Query: 204 SYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAAL 263 S P L G + + + + G +GA G G + PG A Sbjct: 636 SGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGA----RGAPGA-VGAPGPAGAT 690 Query: 264 GEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQ 314 G++ P RG+ G P GP+ +P A GE+ Sbjct: 691 GDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGER 741 Score = 31.6 bits (70), Expect = 1.3 Identities = 53/221 (23%), Positives = 70/221 (31%), Gaps = 53/221 (23%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGP 157 G+R +G G + P PP G +RG LP GV +G++GP Sbjct: 379 GKRGPNGEAGSAGPPGPPGLRGSPGSRG----------LPGADGRAGVMGPPGSRGASGP 428 Query: 158 SRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESL 217 + G RG P GE G P L G Sbjct: 429 A---------GVRG-------------------PNGDAGRPGEPGLMGPRGLPGSPGN-- 458 Query: 218 LLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSR 277 + + + +DG G + GPAG E PG G + G T PG Sbjct: 459 ----IGPAGKEGPVGLPGIDGRPGPI----GPAGARGE-PGNIGFPGPK--GPTGDPGKN 507 Query: 278 RRRRGAGRSA--GWPHPGGPSRPTRRNAPPARPDAAGEQCP 316 + AG + G P P G + P GEQ P Sbjct: 508 GDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGP 548 Score = 28.9 bits (63), Expect = 8.7 Identities = 25/80 (31%), Positives = 28/80 (35%), Gaps = 2/80 (2%) Query: 245 VGHGPAGRELEGPGGG-AALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNA 303 VG GP L GP G A G P G AG P GP + Sbjct: 86 VGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDG 145 Query: 304 PPARPDAAGEQ-CPRPAGAR 322 P +P GE+ P GAR Sbjct: 146 HPGKPGRPGERGVVGPQGAR 165 Score = 28.9 bits (63), Expect = 8.7 Identities = 61/240 (25%), Positives = 76/240 (31%), Gaps = 28/240 (11%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGK--EPKPGGRVTLPALHLPKGVCPHHPGKGSA 155 GR G G S P PP G+ RG + P GR P G G A Sbjct: 793 GRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEA 852 Query: 156 GPSRRGRGQRAKGFRGSE--MNSESRRGQTAAGREKHPRAGCSGE-GETGASYPEELHGH 212 G + +G G+ + RG+ R AG GE G G + P G Sbjct: 853 GTAGPPGTPGPQGLLGAPGILGLPGSRGE----RGLPGVAGAVGEPGPLGIAGPPGARGP 908 Query: 213 EAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQ----RA 268 A+ A DG+ G GP GR+ + PG G Sbjct: 909 PG------AVGSPGVNGAPGEAGRDGNPG----NDGPPGRDGQ-PGHKGERGYPGNIGPV 957 Query: 269 GATTTPGSRRRRRGAGR--SAGWPHPGGPSRPTRRNAP--PARPDAAGEQCPRPAGARPR 324 GA PG AG+ + G P GP P P P+ P P PR Sbjct: 958 GAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPR 1017 >gi|209915594 transcription factor 3 isoform E47 [Homo sapiens] Length = 651 Score = 47.8 bits (112), Expect = 2e-05 Identities = 51/190 (26%), Positives = 68/190 (35%), Gaps = 15/190 (7%) Query: 182 QTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEG 241 Q AG + PRAG G SY LHG +S + + LD+ H HAV GD Sbjct: 361 QGLAGTSQWPRAGAPGA--LSPSYDGGLHG--LQSKIEDHLDEAIHVLRSHAVGTAGDMH 416 Query: 242 ALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPH-----PGGPS 296 L GHG GP +LG + AG G G S H P P Sbjct: 417 TLLPGHGALASGFTGP---MSLGGRHAGLV---GGSHPEDGLAGSTSLMHNHAALPSQPG 470 Query: 297 RPTRRNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHS 356 + PP G A + ++ E E + T + S E R ++ S Sbjct: 471 TLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSS 530 Query: 357 SPLSTSRDPK 366 + S + K Sbjct: 531 TDEVLSLEEK 540 >gi|27777636 transcription factor 3 isoform E12 [Homo sapiens] Length = 654 Score = 47.4 bits (111), Expect = 2e-05 Identities = 50/182 (27%), Positives = 66/182 (36%), Gaps = 17/182 (9%) Query: 182 QTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEG 241 Q AG + PRAG G SY LHG +S + + LD+ H HAV GD Sbjct: 361 QGLAGTSQWPRAGAPGA--LSPSYDGGLHG--LQSKIEDHLDEAIHVLRSHAVGTAGDMH 416 Query: 242 ALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPH-----PGGPS 296 L GHG GP +LG + AG G G S H P P Sbjct: 417 TLLPGHGALASGFTGP---MSLGGRHAGLV---GGSHPEDGLAGSTSLMHNHAALPSQPG 470 Query: 297 RPTRRNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHS 356 + PP G A + ++ E E + T + S E P++ + Sbjct: 471 TLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELK--APRART 528 Query: 357 SP 358 SP Sbjct: 529 SP 530 >gi|60097902 filaggrin [Homo sapiens] Length = 4061 Score = 46.2 bits (108), Expect = 5e-05 Identities = 68/255 (26%), Positives = 88/255 (34%), Gaps = 69/255 (27%) Query: 153 GSAGPSRRGR-GQRAKGFRGSEMNSESRRGQ-TAAGREKHPRAGCSGEGETGASYPEELH 210 G AGPS GR G R + R S +S S+ GQ T G R G G SY E+ Sbjct: 3725 GRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQG------SYHEQ-- 3776 Query: 211 GHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAG----------RELEGPGGG 260 ++D H + H+ +G HG +G E G G Sbjct: 3777 ----------SVDRSGHSGSHHSHTTS--QGRSDASHGQSGSRSASRETRNEEQSGDGSR 3824 Query: 261 AALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAG 320 + +T SR + G G SAG SR +RR D+ E P Sbjct: 3825 HSGSRHHEASTQADSSRHSQSGQGESAG-------SRRSRRQGSSVSQDSDSEAYPE--- 3874 Query: 321 ARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLSTSRD----PKSSYTHTHTHT 376 D E S+S A H S SRD P SS H T + Sbjct: 3875 ----------DSERRSES-----------ASRNHHGSSREQSRDGSRHPGSS--HRDTAS 3911 Query: 377 HTEPAPVLEFSTPVK 391 H + +PV S+ K Sbjct: 3912 HVQSSPVQSDSSTAK 3926 Score = 37.0 bits (84), Expect = 0.032 Identities = 68/298 (22%), Positives = 97/298 (32%), Gaps = 65/298 (21%) Query: 117 AGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFRG----- 171 A V G G +VT H G AGP ++ + A+G G Sbjct: 1378 ASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGR 1437 Query: 172 ---------SEMNSESRRGQTA---AGRE--KHPRAGCSGEGETGASYPEELHGHEAES- 216 S SES GQTA GR+ +H +A S + + GH S Sbjct: 1438 SRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSR 1497 Query: 217 ------LLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAG----------RELEGPGGG 260 +++D H H+ +G HG +G E G G Sbjct: 1498 GGRQGSYHEQSVDRSGHSGYHHSHTTP--QGRSDASHGQSGPRSASRQTRNEEQSGDGSR 1555 Query: 261 AALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAG 320 + +T SR + G G SAG S+ +RR D Sbjct: 1556 HSGSRHHEPSTRAGSSRHSQVGQGESAG-------SKTSRRQGSSVSQD----------- 1597 Query: 321 ARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLSTSRDPKSSYTHTHTHTHT 378 R + E D E S+S S + AR +S SR+P+S +H H+ Sbjct: 1598 -RDSEGHSE-DSERRSESAS---RNHYGSAREQSRHG----SRNPRSHQEDRASHGHS 1646 Score = 34.7 bits (78), Expect = 0.16 Identities = 50/244 (20%), Positives = 76/244 (31%), Gaps = 52/244 (21%) Query: 145 VCPHHPGKGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREK---HPRAGCSGEGET 201 V H + + G +R G+R +G + SR + G++ HP G S G Sbjct: 3390 VSTHEQSESAHGRTRTSTGRR-QGSHHEQARDSSRHSASQEGQDTIRGHP--GSSRRGRQ 3446 Query: 202 GASYPEELH--GHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGR-----EL 254 G+ Y + + GH H R D G Q G A R E Sbjct: 3447 GSHYEQSVDRSGHSGSH----------HSHTTSQGRSDASRG--QSGSRSASRQTRNDEQ 3494 Query: 255 EGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQ 314 G G + +T SR + G G+SAG Sbjct: 3495 SGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAG-------------------------- 3528 Query: 315 CPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHSSPLSTSRDPKSSYTHTHT 374 PR + + ++D + S+ W+ R + SR P S + Sbjct: 3529 -PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAG 3587 Query: 375 HTHT 378 H H+ Sbjct: 3588 HGHS 3591 Score = 33.9 bits (76), Expect = 0.27 Identities = 48/227 (21%), Positives = 78/227 (34%), Gaps = 37/227 (16%) Query: 153 GSAGPSRRGR-GQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHG 211 G GPS R G + R + +S S+ GQ HP G S G G+ Sbjct: 808 GWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTI--RGHP--GSSRRGRQGSH------- 856 Query: 212 HEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGAT 271 HE +++D H + H+ +G G +G R+ + Sbjct: 857 HE------QSVDRSGHSGSHHSHTTS--QGRSDASRGQSG--------------SRSASR 894 Query: 272 TTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQAEIETD 331 TT + R G+ S H R++ + + G + R G+ Q ++D Sbjct: 895 TTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQ---DSD 951 Query: 332 PETGSDSFSTWTSYEFNYARPKSHSSPLSTSRDPKSSYTHTHTHTHT 378 E S+ W+ R + SR P+S + H H+ Sbjct: 952 SEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHS 998 Score = 31.6 bits (70), Expect = 1.3 Identities = 36/142 (25%), Positives = 51/142 (35%), Gaps = 20/142 (14%) Query: 153 GSAGPSRRGRGQ-RAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELH- 210 G GPS GR + R + R S +S S+ GQ HP G S G G+ Y + + Sbjct: 1780 GRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTI--RGHP--GSSRGGRQGSHYEQSVDS 1835 Query: 211 -GHEAESLLLEALDDLAHQAALHAVRLD---GDEGALQVGHGPAGRELEGPGGGAALGEQ 266 GH H R D G G+ V + G G + Sbjct: 1836 SGHSGSH----------HSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRH 1885 Query: 267 RAGATTTPGSRRRRRGAGRSAG 288 ++ SR + G G+S+G Sbjct: 1886 HEASSRADSSRHSQVGQGQSSG 1907 Score = 29.3 bits (64), Expect = 6.6 Identities = 55/234 (23%), Positives = 77/234 (32%), Gaps = 26/234 (11%) Query: 149 HPGKGSAGPSRRGRGQRAKGFR--GSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYP 206 HPG S R G G A R G+ S RGQ A+ E+ S GE S+ Sbjct: 1956 HPG--SHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQ----ARSSAGERHGSH- 2008 Query: 207 EELHGHEAESLLLEALDDLAHQAALHAVRLDGDEG--ALQVGHGPAGRELEGPGGGAALG 264 H+ +S + H A AVR G G Q E +A G Sbjct: 2009 -----HQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQG 2063 Query: 265 EQRAGATTTPGSRRRRRG--AGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGAR 322 + + S R + G +GRS + + + + P G Q G+ Sbjct: 2064 KAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQ-----GSH 2118 Query: 323 PRQAEIETDPETGSDSFSTWTSY--EFNYARPKSHSSPLSTSRDPKSSYTHTHT 374 QA+ + + T + R SH S R S H+HT Sbjct: 2119 YDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQ-SVDRSGHSGSHHSHT 2171 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 46.2 bits (108), Expect = 5e-05 Identities = 65/240 (27%), Positives = 76/240 (31%), Gaps = 23/240 (9%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPGKGSA 155 G R SGA G P PP G A G++ +PG G LP P G KG + Sbjct: 1255 GPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGES 1314 Query: 156 GPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGE-GETGASYPEELHGHEA 214 GPS KG G + S G P GE G G P G + Sbjct: 1315 GPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPP-----GEPGPAGQDGPPGDKGDDG 1369 Query: 215 ESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRE----------LEGPGGGAA-L 263 E + G G GP GR+ LEGP G + Sbjct: 1370 EPGQTGSPGPTGEPGPSGPPGKRGPPGPA----GPEGRQGEKGAKGEAGLEGPPGKTGPI 1425 Query: 264 GEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARP 323 G Q A P R G G P GP P PP P G+ P+ P Sbjct: 1426 GPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHP 1485 Score = 38.1 bits (87), Expect = 0.014 Identities = 59/225 (26%), Positives = 74/225 (32%), Gaps = 44/225 (19%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPGKGSAGPSRRG 161 G RG P PP G GKE G G LP P G+ +G GP Sbjct: 1012 GERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP---- 1067 Query: 162 RGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEA 221 A G +G+E G + E+ P G G P+ G E Sbjct: 1068 --VGALGLKGNE-GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEK----- 1119 Query: 222 LDDLAHQAALHAVRLDGDEGALQVGHGPAGRE-LEGPGG--------GAALGEQRAGATT 272 G++G GPAGR+ L+GP G G + G Sbjct: 1120 -------------GAPGEKGP----QGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIG 1162 Query: 273 TPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPR 317 PG + + G G P P GP P + P A GE PR Sbjct: 1163 EPGQKGSKGDKGEQ-GPPGPTGPQGPIGQPGPSG---ADGEPGPR 1203 Score = 33.1 bits (74), Expect = 0.46 Identities = 67/278 (24%), Positives = 90/278 (32%), Gaps = 53/278 (19%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPG--------GRVTLPALHLPKGVCPHHPGKGSA 155 G G P PP G+ A G++ G G V LP P G KG Sbjct: 1102 GIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEI 1161 Query: 156 G-PSRRGRGQRAKGFRGSE--------MNSESRRGQTAAGREKHPRAGCSGEGETGASYP 206 G P ++G +KG +G + + G + A E PR G+ G P Sbjct: 1162 GEPGQKG----SKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP 1217 Query: 207 EELHGHEAESLLLEALD----DLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGG-- 260 G + L+ L + + + G G P +GP GG Sbjct: 1218 RGFPGPPGP-VGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIG 1276 Query: 261 --AALGEQ----RAGATTTPGS--------RRRRRGAGRSAGWPHPGGPSRPTRRNAP-- 304 A+GE+ AG PG R +G +G P GP P + P Sbjct: 1277 NPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG 1336 Query: 305 -------PARPDAAGEQCPRPAGARPRQAEIETDPETG 335 P P GE P PAG + D E G Sbjct: 1337 SPGPVGFPGDPGPPGE--PGPAGQDGPPGDKGDDGEPG 1372 Score = 32.7 bits (73), Expect = 0.60 Identities = 60/231 (25%), Positives = 77/231 (33%), Gaps = 34/231 (14%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPG----KGSAGP 157 G RG P P GG G PG G++ +P L P +PG KGS G Sbjct: 835 GPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGL-------PGYPGRQGPKGSIGF 887 Query: 158 SRRGRGQRAKGFRGS--EMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAE 215 KG RG+ + +RG T E+ PR G G S + G E Sbjct: 888 PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGE 947 Query: 216 SLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRE-LEG-PGGGAALGEQ-RAGATT 272 G +G GP G++ L G PG G Q + G Sbjct: 948 R---------GPNGPQGPTGFPGPKGP----PGPPGKDGLPGHPGQRGETGFQGKTGPPG 994 Query: 273 TPGSRRRRRGAGRSAGWP---HPGGPSRPTRRNAPPARPDAAGEQCPRPAG 320 PG + G + HPG P P + P + P PAG Sbjct: 995 PPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAG 1045 Score = 30.8 bits (68), Expect = 2.3 Identities = 62/249 (24%), Positives = 76/249 (30%), Gaps = 43/249 (17%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGP 157 G++ GA+G P G+ GK PG +P P G HPGK Sbjct: 721 GQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPG----MPGADGPPG----HPGKEGPPG 772 Query: 158 SRRGRG----------------QRAKGFRG-----SEMNSESRRGQTAAGREKHPRAGCS 196 + G+G + A G RG E + G K R Sbjct: 773 EKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIG 832 Query: 197 GEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEG 256 G G PE G + L + L L G G GP G + Sbjct: 833 PPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGR----QGPKG-SIGF 887 Query: 257 PGGGAALGEQRA-GATTTPGSRRRR--------RGAGRSAGWPHPGGPSRPTRRNAPPAR 307 PG A GE+ G PG R +R RG G P P G S PP Sbjct: 888 PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGE 947 Query: 308 PDAAGEQCP 316 G Q P Sbjct: 948 RGPNGPQGP 956 Score = 30.0 bits (66), Expect = 3.9 Identities = 56/245 (22%), Positives = 73/245 (29%), Gaps = 46/245 (18%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKE--PKPGGRVTLPALHLPKGVC-----PHHP 150 G+ G RGF P G + +G E P P G P P G P P Sbjct: 1048 GKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP 1107 Query: 151 G----------------KGSAGPSRRGRGQRAKGFRG-----SEMNSESRRGQTAAGREK 189 G KG GP+ R Q G G + +G+ +K Sbjct: 1108 GPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQK 1167 Query: 190 HPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGP 249 + +G G + P+ G S A + + GDEG Sbjct: 1168 GSKGDKGEQGPPGPTGPQGPIGQPGPS---GADGEPGPRGQQGLFGQKGDEGP------- 1217 Query: 250 AGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSA--GWPHPGGPSRPTRRNAPPAR 307 R GP G L G PG + G+ G P P GPS + P Sbjct: 1218 --RGFPGPPGPVGL----QGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP 1271 Query: 308 PDAAG 312 P G Sbjct: 1272 PGGIG 1276 >gi|239751449 PREDICTED: hypothetical protein XP_002347867 [Homo sapiens] Length = 315 Score = 46.2 bits (108), Expect = 5e-05 Identities = 63/213 (29%), Positives = 85/213 (39%), Gaps = 32/213 (15%) Query: 119 GQVAARGKEPKPGG---RVTLPALHLPKGVCP---HHPGKGSAGPSRRGRGQRAKGFRGS 172 G+VA G P G RV+ P P+ P H G G+ GP RGR +R +G R Sbjct: 41 GEVAPAGGSPLAVGGAFRVSSPRPFPPRPERPSRRHRAGCGAHGPGSRGR-ERRRGSRDP 99 Query: 173 EMNSESR---RGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQA 229 +R RG++A G P +G +G + P + +L + + Sbjct: 100 PAGPVARARARGRSAPG-SAQPASGAAGPAAAPEAAPP---AWDPATLPPSRKRNSLGSS 155 Query: 230 ALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRR---RRGAGRS 286 LH VRL G ++ GPAG + AL GA R R RRG Sbjct: 156 PLHPVRL----GRVRAHAGPAGTSILRVAPHPAL----PGAQVHWAGRHRWAARRGKSLQ 207 Query: 287 AGWPHPGG------PSRPTRRNAPPARPDAAGE 313 + W PGG P R T APP + A+ E Sbjct: 208 SAWWGPGGRRNSISPGR-TTFPAPPTQEAASRE 239 Score = 32.7 bits (73), Expect = 0.60 Identities = 25/91 (27%), Positives = 35/91 (38%), Gaps = 2/91 (2%) Query: 274 PGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCP--RPAGARPRQAEIETD 331 PGSR R R G P +R R+AP + A+G P P A P Sbjct: 85 PGSRGRERRRGSRDPPAGPVARARARGRSAPGSAQPASGAAGPAAAPEAAPPAWDPATLP 144 Query: 332 PETGSDSFSTWTSYEFNYARPKSHSSPLSTS 362 P +S + + R ++H+ P TS Sbjct: 145 PSRKRNSLGSSPLHPVRLGRVRAHAGPAGTS 175 >gi|239745954 PREDICTED: hypothetical protein XP_002343623 [Homo sapiens] Length = 315 Score = 46.2 bits (108), Expect = 5e-05 Identities = 63/213 (29%), Positives = 85/213 (39%), Gaps = 32/213 (15%) Query: 119 GQVAARGKEPKPGG---RVTLPALHLPKGVCP---HHPGKGSAGPSRRGRGQRAKGFRGS 172 G+VA G P G RV+ P P+ P H G G+ GP RGR +R +G R Sbjct: 41 GEVAPAGGSPLAVGGAFRVSSPRPFPPRPERPSRRHRAGCGAHGPGSRGR-ERRRGSRDP 99 Query: 173 EMNSESR---RGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQA 229 +R RG++A G P +G +G + P + +L + + Sbjct: 100 PAGPVARARARGRSAPG-SAQPASGAAGPAAAPEAAPP---AWDPATLPPSRKRNSLGSS 155 Query: 230 ALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRR---RRGAGRS 286 LH VRL G ++ GPAG + AL GA R R RRG Sbjct: 156 PLHPVRL----GRVRAHAGPAGTSILRVAPHPAL----PGAQVHWAGRHRWAARRGKSLQ 207 Query: 287 AGWPHPGG------PSRPTRRNAPPARPDAAGE 313 + W PGG P R T APP + A+ E Sbjct: 208 SAWWGPGGRRNSISPGR-TTFPAPPTQEAASRE 239 Score = 32.7 bits (73), Expect = 0.60 Identities = 25/91 (27%), Positives = 35/91 (38%), Gaps = 2/91 (2%) Query: 274 PGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCP--RPAGARPRQAEIETD 331 PGSR R R G P +R R+AP + A+G P P A P Sbjct: 85 PGSRGRERRRGSRDPPAGPVARARARGRSAPGSAQPASGAAGPAAAPEAAPPAWDPATLP 144 Query: 332 PETGSDSFSTWTSYEFNYARPKSHSSPLSTS 362 P +S + + R ++H+ P TS Sbjct: 145 PSRKRNSLGSSPLHPVRLGRVRAHAGPAGTS 175 >gi|239756937 PREDICTED: hypothetical protein [Homo sapiens] Length = 294 Score = 45.8 bits (107), Expect = 7e-05 Identities = 63/213 (29%), Positives = 85/213 (39%), Gaps = 32/213 (15%) Query: 119 GQVAARGKEPKPGG---RVTLPALHLPKGVCP---HHPGKGSAGPSRRGRGQRAKGFRGS 172 G+VA G P G RV+ P P+ P H G G+ GP RGR +R +G R Sbjct: 41 GEVAPAGGSPLAVGGAFRVSSPRPFPPRPERPSRRHRAGCGAHGPGSRGR-ERRRGSRDP 99 Query: 173 EMNSESR---RGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQA 229 +R RG++A G P +G +G + P + +L + + Sbjct: 100 PAGPVARARARGRSAPG-SAQPASGAAGPAAAPEAAPP---AWDPATLPPSRKRNSLGSS 155 Query: 230 ALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRR---RRGAGRS 286 LH VRL G ++ GPAG + AL GA R R RRG Sbjct: 156 PLHPVRL----GRVRAHAGPAGPSILRVAPHPAL----PGAQVHWAGRHRWAARRGKSLQ 207 Query: 287 AGWPHPGG------PSRPTRRNAPPARPDAAGE 313 + W PGG P R T APP + A+ E Sbjct: 208 SAWWGPGGRRNSISPGR-TTFPAPPTQEAASRE 239 Score = 30.4 bits (67), Expect = 3.0 Identities = 24/91 (26%), Positives = 34/91 (37%), Gaps = 2/91 (2%) Query: 274 PGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCP--RPAGARPRQAEIETD 331 PGSR R R G P +R R+AP + A+G P P A P Sbjct: 85 PGSRGRERRRGSRDPPAGPVARARARGRSAPGSAQPASGAAGPAAAPEAAPPAWDPATLP 144 Query: 332 PETGSDSFSTWTSYEFNYARPKSHSSPLSTS 362 P +S + + R ++H+ P S Sbjct: 145 PSRKRNSLGSSPLHPVRLGRVRAHAGPAGPS 175 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 45.4 bits (106), Expect = 9e-05 Identities = 65/229 (28%), Positives = 77/229 (33%), Gaps = 28/229 (12%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPGKGSAGPSRRG 161 G G + P P A GQ A+G PG G P P G P PG G GP Sbjct: 377 GPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSG--PQGPG-GPPGP---- 429 Query: 162 RGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEA 221 KG G E + +G T A E P G G G + L Sbjct: 430 -----KGNSG-EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483 Query: 222 LDDLAHQAALHAVRLDGDEGALQVGHGPAG-RELEGPGG--GAALGEQRAGATTTPGSRR 278 + + DG G GPAG R GP G G+ R G PG++ Sbjct: 484 PGERGGPGSRGFPGADGVAGP----KGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKG 539 Query: 279 RRRGAGRSA--GWPHPGGPSRPTRRNAPPARPDAAGEQ----CPRPAGA 321 G G P GP+ R PP P A G+ P P GA Sbjct: 540 LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGA 588 Score = 42.7 bits (99), Expect = 6e-04 Identities = 58/249 (23%), Positives = 75/249 (30%), Gaps = 24/249 (9%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--------------GRVTLPALHLPK 143 G SG G P PP G GK +PG G LP + + Sbjct: 209 GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHR 268 Query: 144 GVCPHHPGKGSAGPSRRGRGQRAKGFRGS--EMNSESRRGQTAAGREKHPRAGCSGEGET 201 G KG AGP+ + G G+ +M G+ P +G T Sbjct: 269 GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGAT 328 Query: 202 GASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGA 261 GA+ P G A+ +G +G P GP G Sbjct: 329 GAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP 388 Query: 262 ALGEQRA--GATTTPGSRRRRR--GAGRSAGWPHPGGPSRPTRRNAPPARP----DAAGE 313 Q GA PG GA +G PGGP P + P P D + Sbjct: 389 GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK 448 Query: 314 QCPRPAGAR 322 P P G + Sbjct: 449 GEPGPVGVQ 457 Score = 41.6 bits (96), Expect = 0.001 Identities = 69/243 (28%), Positives = 79/243 (32%), Gaps = 32/243 (13%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGP 157 G+R G G P P G A G E P G + P L P G G+ G Sbjct: 965 GQRGERGFPGLPGPSGEPGKQGPSGASG-ERGPPGPMGPPGLAGPPGESGREGAPGAEGS 1023 Query: 158 SRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHP--RAGCSGE-GETGASYPEELHGHEA 214 R AKG RG E G A P AG SG+ GETG + P G Sbjct: 1024 PGRDGSPGAKGDRG-ETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVG 1082 Query: 215 ESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRE----LEGPGGG-AALGEQRAG 269 A R D E Q G G L+GP G + GEQ Sbjct: 1083 AR----------GPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPS 1132 Query: 270 ATTTPGSRRRRRGAGRSA------GWPHPGGPSRPTRRN------APPARPDAAGEQCPR 317 + P R G+ + G P P GP P R PP P G P Sbjct: 1133 GASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPP 1192 Query: 318 PAG 320 AG Sbjct: 1193 SAG 1195 Score = 41.2 bits (95), Expect = 0.002 Identities = 57/233 (24%), Positives = 75/233 (32%), Gaps = 28/233 (12%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGP 157 G GARG P P G+ G PG + PKG G AGP Sbjct: 464 GEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGA----DGVAGPKGPAGERGSPGPAGP 519 Query: 158 SRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESL 217 +G + R E +G T + P +G+TG P G Sbjct: 520 ----KGSPGEAGRPGEAGLPGAKGLTGSPGSPGP------DGKTGPPGPAGQDGRPGPP- 568 Query: 218 LLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGG--GAALGEQRAGATTTPG 275 + + G +GA R + GP G G A + AGA PG Sbjct: 569 -----GPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPG 623 Query: 276 -----SRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQ-CPRPAGAR 322 R +G S G+ GP+ P P G+ P P+GAR Sbjct: 624 PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676 Score = 40.8 bits (94), Expect = 0.002 Identities = 64/241 (26%), Positives = 84/241 (34%), Gaps = 32/241 (13%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGK----- 152 G+ +GA+G PP G RG E P G L P G P GK Sbjct: 611 GKDGEAGAQG------PPGPAGPAGERG-EQGPAGSPGFQGLPGPAGP-PGEAGKPGEQG 662 Query: 153 -----GSAGPSRRGRGQRA----KGFRGSEMNSESRRGQTAAGRE--KHPRAGCSGEGET 201 G+ GPS RG+R +G +G + R A G + K G Sbjct: 663 VPGDLGAPGPSG-ARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQ 721 Query: 202 GASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGA 261 GA + + G + L D A G +G + GP G PG Sbjct: 722 GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLT-GPIGP----PGPAG 776 Query: 262 ALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGA 321 A G++ + P RGA G P P GP+ +P A GE P AGA Sbjct: 777 APGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE--PGDAGA 834 Query: 322 R 322 + Sbjct: 835 K 835 Score = 38.9 bits (89), Expect = 0.008 Identities = 61/240 (25%), Positives = 77/240 (32%), Gaps = 32/240 (13%) Query: 104 GARGFSAPCCPPAAGGQVAAR---GKEPKPGGRVTLPALHLPKGV--CPHHPG----KGS 154 G G P PP GG A + G + K G +++P P G P PG +G Sbjct: 142 GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201 Query: 155 AGPSRRGRGQRAKGFRG--------SEMNSESRRGQTAAGREKHPRAGCSGEGETGASYP 206 GP A G G + + G+ E+ P G G + Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261 Query: 207 EELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQ 266 + GH S L A D G+ GA GP G GE+ Sbjct: 262 PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA-PGQMGPRGLP----------GER 310 Query: 267 RAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPR----PAGAR 322 P R GA +AG P P GP+ P AG Q PR P G R Sbjct: 311 GRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR 370 Score = 34.7 bits (78), Expect = 0.16 Identities = 63/241 (26%), Positives = 78/241 (32%), Gaps = 24/241 (9%) Query: 97 VGRRRGSGARGFSAPCCPPAAGGQVAARGK--EPKPGGRVTLPALHLPKGVCPHHPGKGS 154 +G GA+G PP A G A G+ P P G P P G +G Sbjct: 853 IGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGE 912 Query: 155 AGPSRRGRGQRAKGFRG--SEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGH 212 GP+ R G G E S G A P+ G G P + G Sbjct: 913 TGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVG--LPGQ-RGE 969 Query: 213 EAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGG-----GAALGEQR 267 L + Q A G G + GP G L GP G GA E Sbjct: 970 RGFPGLPGPSGEPGKQGPSGASGERGPPGPM----GPPG--LAGPPGESGREGAPGAEGS 1023 Query: 268 AGATTTPGSRRRRRGAGRSA-----GWPHPGGPSRPTRRNAPPARPDAAGEQCP-RPAGA 321 G +PG++ R G + G P GP P ++ AG P P GA Sbjct: 1024 PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGA 1083 Query: 322 R 322 R Sbjct: 1084 R 1084 Score = 29.6 bits (65), Expect = 5.1 Identities = 64/250 (25%), Positives = 81/250 (32%), Gaps = 22/250 (8%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPGKGSAGPSRRG 161 G RG + P G +G + PG G L P G KG +GPS Sbjct: 731 GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790 Query: 162 RGQRAKGFRGSEMNSESRRGQTA----AGREKHPRA----GCSGE-GETGASYPEELHGH 212 A+G G RG+ AG P A G GE G+ GA G Sbjct: 791 GPTGARGAPGD-------RGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGP 843 Query: 213 EAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRE-LEGPGGGAALGEQR--AG 269 + + ++ A A G GA G AGR GP G A AG Sbjct: 844 AGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFP-GAAGRVGPPGPSGNAGPPGPPGPAG 902 Query: 270 ATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQAEIE 329 G R AGR PG P + +P A A P P G ++ + Sbjct: 903 KEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVG 962 Query: 330 TDPETGSDSF 339 + G F Sbjct: 963 LPGQRGERGF 972 >gi|13489073 egl nine homolog 1 [Homo sapiens] Length = 426 Score = 45.1 bits (105), Expect = 1e-04 Identities = 44/167 (26%), Positives = 62/167 (37%), Gaps = 15/167 (8%) Query: 232 HAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPH 291 H + G EGAL GHG + GP AA+ RAGA + RR A Sbjct: 54 HKLVCQGSEGAL--GHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNAS------- 104 Query: 292 PGGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYAR 351 G ++ + PPA P AA C AG + E +P G + +S + Sbjct: 105 -GDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEP--GKEEPPARSSL---FQE 158 Query: 352 PKSHSSPLSTSRDPKSSYTHTHTHTHTEPAPVLEFSTPVKAICCFHH 398 + P +T D S + T+P P L+ + C H Sbjct: 159 KANLYPPSNTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKH 205 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 44.7 bits (104), Expect = 2e-04 Identities = 67/253 (26%), Positives = 84/253 (33%), Gaps = 32/253 (12%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRG 163 GA+G P P + G RG EP P G P G+ GKG GP+ Sbjct: 348 GAKGEVGPAGSPGSNGAPGQRG-EPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGA 406 Query: 164 QRAKGFRGSE-----------MNSESRRGQTAAGREKHPRAGCSGE----GETGASYPEE 208 G RG G+ A E PR G GE G GA + Sbjct: 407 PGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR-GERGEAGIPGVPGAKGEDG 465 Query: 209 LHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAG-RELEGPGG--GAALGE 265 G E L A + R + GPAG R GP G GAA Sbjct: 466 KDGSPGEPGA-NGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEP 524 Query: 266 QRAGATTTPGSRRRRRGAGRSAGWP-HPGGPSRPTRRNAPPARPDAAGEQCPRPAGARPR 324 R G PG R G P PGGP + P ++ ++ P P+G R + Sbjct: 525 GRDGVPGGPGMR----------GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQ 574 Query: 325 QAEIETDPETGSD 337 + G+D Sbjct: 575 PGVMGFPGPKGND 587 Score = 43.1 bits (100), Expect = 4e-04 Identities = 62/230 (26%), Positives = 76/230 (33%), Gaps = 38/230 (16%) Query: 103 SGARGFSAPCCPPAAGGQVAARGKEPKPG-----GRVTLPALHLPKGV--------CPHH 149 SG RG P P G G++ PG GR P +G P H Sbjct: 989 SGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGH 1048 Query: 150 PGK-GSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEE 208 PG G GP+ + G R + + G A + PR +GETG Sbjct: 1049 PGPPGPVGPAGKS-GDRGESGPAGPAGAPGPAGSRGAPGPQGPRGD---KGETGERGAAG 1104 Query: 209 LHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAG-RELEGPGG--GAALGE 265 + GH + A + G +GA+ GPAG R GP G G Sbjct: 1105 IKGHRGFP---------GNPGAPGSPGPAGQQGAIG-SPGPAGPRGPVGPSGPPGKDGTS 1154 Query: 266 QRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQC 315 G PG R R G HPG P PP P A G C Sbjct: 1155 GHPGPIGPPGPRGNRGERGSEGSPGHPGQP-------GPPGPPGAPGPCC 1197 Score = 42.4 bits (98), Expect = 8e-04 Identities = 76/253 (30%), Positives = 90/253 (35%), Gaps = 34/253 (13%) Query: 97 VGRRRGSGARGFSAPCCPPAAG--GQVAARGKEPKPGGRVTLPALHLPKGVC--PHHPG- 151 +G R G RG P P AAG G ARG + +PG P P G P PG Sbjct: 299 MGPRGAPGERG--RPGLPGAAGARGNDGARGSDGQPGP----PG---PPGTAGFPGSPGA 349 Query: 152 KGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHG 211 KG GP+ A G RG E + G G+GE G + G Sbjct: 350 KGEVGPAGSPGSNGAPGQRG-EPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA------G 402 Query: 212 HEAESLLLEALDDLAHQAALHAVRLDGDEG-----ALQVGHGPAGRELEG--PGGGAALG 264 L+ A A A L G G + GP G E PG A G Sbjct: 403 IPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKG 462 Query: 265 EQ-RAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQ-CPRPAGAR 322 E + G+ PG+ GA G P GP+ P N P AGE+ P PAG R Sbjct: 463 EDGKDGSPGEPGA-NGLPGAAGERGAPGFRGPAGP---NGIPGEKGPAGERGAPGPAGPR 518 Query: 323 PRQAEIETDPETG 335 E D G Sbjct: 519 GAAGEPGRDGVPG 531 Score = 41.2 bits (95), Expect = 0.002 Identities = 66/249 (26%), Positives = 81/249 (32%), Gaps = 46/249 (18%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGP 157 G R G +G P A G RG P G LP L G GS G Sbjct: 966 GPRGSPGPQGVKGESGKPGANGLSGERG----PPGPQGLPGLAGTAGEPGRDGNPGSDGL 1021 Query: 158 SRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPR-------AGCSGE-GETGASYPEEL 209 R KG RG + A G HP AG SG+ GE+G + P Sbjct: 1022 PGRDGSPGGKGDRGENGSPG------APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGA 1075 Query: 210 HGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAG 269 G G GA GP G + E GAA + G Sbjct: 1076 PGPA------------------------GSRGA-PGPQGPRGDKGETGERGAAGIKGHRG 1110 Query: 270 ATTTPGSRRRRRGAGRSA--GWPHPGGPSRPTRRNAPPARPDAAGEQCP-RPAGARPRQA 326 PG+ AG+ G P P GP P + PP + +G P P G R + Sbjct: 1111 FPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRG 1170 Query: 327 EIETDPETG 335 E ++ G Sbjct: 1171 ERGSEGSPG 1179 Score = 40.4 bits (93), Expect = 0.003 Identities = 56/226 (24%), Positives = 75/226 (33%), Gaps = 24/226 (10%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRG 163 G +G P P A G + ARG P P G P L G + KG GP RG Sbjct: 393 GGKGEMGPAGIPGAPGLMGARGP-PGPAGANGAPGLRGGAGEPGKNGAKGEPGP----RG 447 Query: 164 QRAKGFRGSEMNSESRRGQTAAGREKHPRA--GCSGE----GETGASYPEELHGHEAESL 217 +R + ++ G+ + E G +GE G G + P + G + + Sbjct: 448 ERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG 507 Query: 218 LLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAAL-------GEQRAGA 270 A + A G+ G V GP R + G GG G Q Sbjct: 508 ERGAPGPAGPRGAA------GEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESG 561 Query: 271 TTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCP 316 P RG G+P P G +N P G Q P Sbjct: 562 RPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP 607 Score = 38.9 bits (89), Expect = 0.008 Identities = 53/210 (25%), Positives = 64/210 (30%), Gaps = 48/210 (22%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPG-KGSAGPSRRGR 162 G RG + P PP GQ +G+ PG LP + P+G PG +G GP Sbjct: 759 GPRGPTGPIGPPGPAGQPGDKGEGGAPG----LPGIAGPRG----SPGERGETGPPGPAG 810 Query: 163 GQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEAL 222 A G G E + RG E P G +G + P G + E Sbjct: 811 FPGAPGQNG-EPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER------ 863 Query: 223 DDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRG 282 G G P R L GP PGS Sbjct: 864 ---------------GSPGGPGAAGFPGARGLPGP----------------PGSNGNPGP 892 Query: 283 AGRSAGWPHPGGPSRPTRRNAPPARPDAAG 312 G S G P GP P P P +G Sbjct: 893 PGPS-GSPGKDGPPGPAGNTGAPGSPGVSG 921 Score = 35.8 bits (81), Expect = 0.071 Identities = 68/244 (27%), Positives = 81/244 (33%), Gaps = 53/244 (21%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGK----G 153 G + +G RG P P A G+ G++ PGG P G P GK G Sbjct: 501 GEKGPAGERGAPGPAGPRGAAGEP---GRDGVPGGPGMRGMPGSPGG--PGSDGKPGPPG 555 Query: 154 SAGPSRRGRGQRAKGFRGSE--MNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHG 211 S G S R G RG M +G A + R G G G G P +G Sbjct: 556 SQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG---PPGKNG 612 Query: 212 HEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRE-LEG-PGGGAALGEQR-- 267 + Q GD+G GP G + L+G PG G GE Sbjct: 613 ------------ETGPQGPPGPTGPGGDKGDT----GPPGPQGLQGLPGTGGPPGENGKP 656 Query: 268 --------AGATTTPGSRRR-----RRGAGRSAGWPH------PGGPSRPTRRNAPPARP 308 AGA PG + RG AG P P GP PP P Sbjct: 657 GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPP 716 Query: 309 DAAG 312 AAG Sbjct: 717 GAAG 720 Score = 33.9 bits (76), Expect = 0.27 Identities = 50/205 (24%), Positives = 64/205 (31%), Gaps = 19/205 (9%) Query: 115 PAAGGQVAARGKEPKPGGRVTLPALHLP--KGVCPHHPGKGSAGPSRRGRGQRAKGFRGS 172 P A G A G+ PG R +P KG G AGP RG + R Sbjct: 473 PGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGP----RGAAGEPGRDG 528 Query: 173 EMNSESRRGQTAA--GREKHPRAGCSG-EGETGASYPEELHGHEAESLLLEALDDLAHQA 229 RG + G + G G +GE+G P G + ++ + Sbjct: 529 VPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGN-- 586 Query: 230 ALHAVRLDGDEGALQVGHGPAGRELEGPGG-GAALGEQRAGATTTPGSRRRRRGAGRSAG 288 DG G GP G +GP G G Q T PG + G G Sbjct: 587 -------DGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQG 639 Query: 289 WPHPGGPSRPTRRNAPPARPDAAGE 313 G P N P P G+ Sbjct: 640 LQGLPGTGGPPGENGKPGEPGPKGD 664 Score = 30.0 bits (66), Expect = 3.9 Identities = 66/249 (26%), Positives = 77/249 (30%), Gaps = 52/249 (20%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPG-----GRVTLPALHLPKGVCPHHPGK-GSAGP 157 G G+ P PP G G PG G P P G P PG G +GP Sbjct: 168 GLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGP-PGPPGAIGPSGP 226 Query: 158 S-------RRGR-GQRA-------------------KGFRGSEMNSESRRGQTAAGREKH 190 + R GR G+R KG RG + +G+T A K Sbjct: 227 AGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD-GRNGEKGETGAPGLKG 285 Query: 191 PRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPA 250 G G P G L A + A + DG G GP Sbjct: 286 ENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGS---DGQPGP----PGPP 338 Query: 251 GRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPP---AR 307 G PG A GE G +PGS GA G P P G + PP Sbjct: 339 G-TAGFPGSPGAKGE--VGPAGSPGS----NGAPGQRGEPGPQGHAGAQGPPGPPGINGS 391 Query: 308 PDAAGEQCP 316 P GE P Sbjct: 392 PGGKGEMGP 400 Score = 30.0 bits (66), Expect = 3.9 Identities = 58/242 (23%), Positives = 77/242 (31%), Gaps = 23/242 (9%) Query: 103 SGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGR 162 +G G S P PP G RG PG A LP G + G GPS Sbjct: 842 AGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLP-GPPGSNGNPGPPGPSGSPG 900 Query: 163 GQRAKGFRGS--EMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLE 220 G G+ S G + + +G GA P + G L Sbjct: 901 KDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAG 960 Query: 221 ALDDLAHQAALHAVRLDGDEG-----ALQVGHGPAGRE----LEGPGG-----GAALGEQ 266 + + + G+ G L GP G + L G G G + Sbjct: 961 PPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDG 1020 Query: 267 RAGATTTPGSRRRR-----RGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQ-CPRPAG 320 G +PG + R GA + G P P GP P ++ AG P PAG Sbjct: 1021 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080 Query: 321 AR 322 +R Sbjct: 1081 SR 1082 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 44.3 bits (103), Expect = 2e-04 Identities = 70/253 (27%), Positives = 89/253 (35%), Gaps = 38/253 (15%) Query: 98 GRRRGSGARGFSAP------CCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHH 149 G R G RG + P PP A GQ A+G++ + G G P P G Sbjct: 816 GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 875 Query: 150 PGKGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGE----GETGASY 205 G GP KG RG++ + AAGR P G +G G G S Sbjct: 876 GPTGVTGP---------KGARGAQGPPGATGFPGAAGRVGPP--GSNGNPGPPGPPGPSG 924 Query: 206 PEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGE 265 + G +S + Q G+ G GP+G EGP G L Sbjct: 925 KDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPG----DDGPSG--AEGPPGPQGLAG 978 Query: 266 QRAGATTTPGSRRRRRGAGRSAGWPHPGGPS-RPTRRNAPPARPDAAGEQCPRPAGARPR 324 QR G PG R R G+P GPS P ++ AP A D P G Sbjct: 979 QR-GIVGLPGQRGER-------GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 1030 Query: 325 QAEIETDPETGSD 337 E + G+D Sbjct: 1031 AGEPGREGSPGAD 1043 Score = 43.1 bits (100), Expect = 4e-04 Identities = 69/246 (28%), Positives = 82/246 (33%), Gaps = 34/246 (13%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG-----GRVTLPALHLPKGV-----CP 147 G SG RG P PP G G+E PG GR + +G P Sbjct: 1008 GAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAP 1067 Query: 148 HHPG-KGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYP 206 PG GS GP+ Q +G G++ G A + P+ +GE G Sbjct: 1068 GAPGPPGSPGPAGPTGKQGDRGEAGAQ-GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1126 Query: 207 EELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGG--GAALG 264 L GH + L Q GD+GA GPAG GP G G Sbjct: 1127 RGLKGHRGFTGL---------QGLPGPPGPSGDQGA----SGPAGP--SGPRGPPGPVGP 1171 Query: 265 EQRAGATTTPG-----SRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPA 319 + GA PG R R G AG P GP P P A PR Sbjct: 1172 SGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREK 1231 Query: 320 GARPRQ 325 G P Q Sbjct: 1232 GPDPLQ 1237 Score = 42.4 bits (98), Expect = 8e-04 Identities = 64/232 (27%), Positives = 76/232 (32%), Gaps = 22/232 (9%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKE--PKPGGRVTLPALHLPKGVCPHH-----P 150 G R G G + PP G RG++ P P G LP P G P Sbjct: 627 GLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 686 Query: 151 GKGSAGPSRRGRGQRA-KGFRGSE--MNSESRRGQTAAGREKHPRAGCSGEGETGASYPE 207 G+ A RG+R G RGS + RG P+ G GA P Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 746 Query: 208 ELHGHEAESLLLEALDDLAHQAALHAVRLD-GDEGALQVGHGPAGRELEGP----GGGAA 262 L G E A A R D G++G GR L GP G A Sbjct: 747 GLQGMPGER-------GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799 Query: 263 LGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQ 314 GE+ P RGA G P GP+ +P A GEQ Sbjct: 800 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 851 Score = 37.7 bits (86), Expect = 0.019 Identities = 60/231 (25%), Positives = 74/231 (32%), Gaps = 32/231 (13%) Query: 96 RVGRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSA 155 RVG +G G P P G ARG P GR P L P G G Sbjct: 904 RVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP-GRAGEPGLQGPAGPPGEKGEPGDD 962 Query: 156 GPSRRGRGQRAKGFRGSE--MNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHE 213 GPS +G G + +RG+ P +G GAS G Sbjct: 963 GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 1022 Query: 214 AESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQ-RAGATT 272 L + +G GA GP GR+ G G++ GA Sbjct: 1023 GPPGLTGPAGEPGR---------EGSPGA----DGPPGRD----GAAGVKGDRGETGAVG 1065 Query: 273 TPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPR-PAGAR 322 PG + G P GP+ PT + A G P PAGAR Sbjct: 1066 APG----------APGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1106 Score = 36.2 bits (82), Expect = 0.054 Identities = 62/256 (24%), Positives = 80/256 (31%), Gaps = 39/256 (15%) Query: 104 GARGFSAPCCPPAAGGQVAAR---GKEPKPGGRVTLPALHLPKG-VCPHHPGKGSAGPSR 159 G G P PP GG AA+ G + K GG L + P G + P P + P Sbjct: 162 GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGG-AQLGVMQGPMGPMGPRGPPGPAGAPGP 220 Query: 160 RG----------------RGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGA 203 +G G R + + G+ E+ P G G Sbjct: 221 QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGT 280 Query: 204 SYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAAL 263 + GH LD +A V+ G+ G+ P GP G L Sbjct: 281 PGLPGVKGHRG----YPGLDGAKGEAGAPGVK--GESGS------PGENGSPGPMGPRGL 328 Query: 264 GEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPR----PA 319 +R T P RG G P GP P P P A GE P P Sbjct: 329 PGERG--RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 386 Query: 320 GARPRQAEIETDPETG 335 GA+ + E T G Sbjct: 387 GAQGPRGEPGTPGSPG 402 Score = 35.0 bits (79), Expect = 0.12 Identities = 65/249 (26%), Positives = 79/249 (31%), Gaps = 31/249 (12%) Query: 96 RVGRRRGSGARGFSA---PCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHH- 149 R G +GARG P PP G G PG G P+G Sbjct: 334 RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRG 393 Query: 150 -PGK-GSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPE 207 PG GS GP+ G G++ S G A PR +G TG P+ Sbjct: 394 EPGTPGSPGPAGASGNPGTDGIPGAK-GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 452 Query: 208 ELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEG-----PGGGAA 262 G +A + + Q GPAG E + PGG Sbjct: 453 GQTGEPG----------IAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP 502 Query: 263 LGEQRAGATTTPGSRR--RRRGAGRSAGWPHPGGPSR---PTRRNAPPARPDAAGEQCPR 317 +G G PG+R + G G P GPS P N P RP G R Sbjct: 503 IGPP--GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560 Query: 318 PAGARPRQA 326 RP A Sbjct: 561 GLTGRPGDA 569 Score = 34.3 bits (77), Expect = 0.21 Identities = 65/234 (27%), Positives = 80/234 (34%), Gaps = 20/234 (8%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPGK----GSAG- 156 G G P PP G +G + PG G + P+G P PGK G AG Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP-PGPPGKPGDDGEAGK 259 Query: 157 PSRRG-RG----QRAKGFRGSE--MNSESRRGQTAAGREKHPRAGCSGEGETGASYPEEL 209 P + G RG Q A+GF G+ + RG K +GE+G+ Sbjct: 260 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS 319 Query: 210 HGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGH--GPAGRELEGPGGGAALGEQR 267 G L A A DG G GPAG PG A GE Sbjct: 320 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP-GFPGAPGAKGEAG 378 Query: 268 AGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGA 321 P + RG + G P P G S + P +AG P AGA Sbjct: 379 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAG--APGIAGA 430 Score = 32.3 bits (72), Expect = 0.78 Identities = 63/238 (26%), Positives = 73/238 (30%), Gaps = 31/238 (13%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPG-----GRVTLPALHLPKGVCPHHPGKGSAGPS 158 GARGF P G +G PG G P + G + G GP Sbjct: 273 GARGF------PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP- 325 Query: 159 RRGRGQRAKGFRGSEMNSESRRGQTA----------AGREKHPRA-GCSGE-GETGASYP 206 R G+R + + GQ AG P A G GE G TGA P Sbjct: 326 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385 Query: 207 EELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEG-PGGGAALGE 265 E G E A DG GA P G PG G Sbjct: 386 EGAQGPRGEP---GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 442 Query: 266 QRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARP 323 Q A T P + + G AG+ GP P P AGE+ R A P Sbjct: 443 QGA---TGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 497 Score = 28.9 bits (63), Expect = 8.7 Identities = 29/94 (30%), Positives = 33/94 (35%), Gaps = 11/94 (11%) Query: 97 VGRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAG 156 VG GA G P PP G+ G PG P P G P PG G Sbjct: 1169 VGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGN----PG---PPGP-PGPPGPGIDM 1220 Query: 157 PSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKH 190 + G G R K G + R Q A G +H Sbjct: 1221 SAFAGLGPREK---GPDPLQYMRADQAAGGLRQH 1251 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 44.3 bits (103), Expect = 2e-04 Identities = 70/253 (27%), Positives = 89/253 (35%), Gaps = 38/253 (15%) Query: 98 GRRRGSGARGFSAP------CCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHH 149 G R G RG + P PP A GQ A+G++ + G G P P G Sbjct: 747 GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 806 Query: 150 PGKGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGE----GETGASY 205 G GP KG RG++ + AAGR P G +G G G S Sbjct: 807 GPTGVTGP---------KGARGAQGPPGATGFPGAAGRVGPP--GSNGNPGPPGPPGPSG 855 Query: 206 PEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGE 265 + G +S + Q G+ G GP+G EGP G L Sbjct: 856 KDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPG----DDGPSG--AEGPPGPQGLAG 909 Query: 266 QRAGATTTPGSRRRRRGAGRSAGWPHPGGPS-RPTRRNAPPARPDAAGEQCPRPAGARPR 324 QR G PG R R G+P GPS P ++ AP A D P G Sbjct: 910 QR-GIVGLPGQRGER-------GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 961 Query: 325 QAEIETDPETGSD 337 E + G+D Sbjct: 962 AGEPGREGSPGAD 974 Score = 43.1 bits (100), Expect = 4e-04 Identities = 69/246 (28%), Positives = 82/246 (33%), Gaps = 34/246 (13%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG-----GRVTLPALHLPKGV-----CP 147 G SG RG P PP G G+E PG GR + +G P Sbjct: 939 GAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAP 998 Query: 148 HHPG-KGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYP 206 PG GS GP+ Q +G G++ G A + P+ +GE G Sbjct: 999 GAPGPPGSPGPAGPTGKQGDRGEAGAQ-GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1057 Query: 207 EELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGG--GAALG 264 L GH + L Q GD+GA GPAG GP G G Sbjct: 1058 RGLKGHRGFTGL---------QGLPGPPGPSGDQGA----SGPAGP--SGPRGPPGPVGP 1102 Query: 265 EQRAGATTTPG-----SRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPA 319 + GA PG R R G AG P GP P P A PR Sbjct: 1103 SGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREK 1162 Query: 320 GARPRQ 325 G P Q Sbjct: 1163 GPDPLQ 1168 Score = 42.4 bits (98), Expect = 8e-04 Identities = 64/232 (27%), Positives = 76/232 (32%), Gaps = 22/232 (9%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKE--PKPGGRVTLPALHLPKGVCPHH-----P 150 G R G G + PP G RG++ P P G LP P G P Sbjct: 558 GLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 617 Query: 151 GKGSAGPSRRGRGQRA-KGFRGSE--MNSESRRGQTAAGREKHPRAGCSGEGETGASYPE 207 G+ A RG+R G RGS + RG P+ G GA P Sbjct: 618 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 677 Query: 208 ELHGHEAESLLLEALDDLAHQAALHAVRLD-GDEGALQVGHGPAGRELEGP----GGGAA 262 L G E A A R D G++G GR L GP G A Sbjct: 678 GLQGMPGER-------GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 730 Query: 263 LGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQ 314 GE+ P RGA G P GP+ +P A GEQ Sbjct: 731 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 782 Score = 37.7 bits (86), Expect = 0.019 Identities = 60/231 (25%), Positives = 74/231 (32%), Gaps = 32/231 (13%) Query: 96 RVGRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSA 155 RVG +G G P P G ARG P GR P L P G G Sbjct: 835 RVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP-GRAGEPGLQGPAGPPGEKGEPGDD 893 Query: 156 GPSRRGRGQRAKGFRGSE--MNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHE 213 GPS +G G + +RG+ P +G GAS G Sbjct: 894 GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 953 Query: 214 AESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQ-RAGATT 272 L + +G GA GP GR+ G G++ GA Sbjct: 954 GPPGLTGPAGEPGR---------EGSPGA----DGPPGRD----GAAGVKGDRGETGAVG 996 Query: 273 TPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPR-PAGAR 322 PG + G P GP+ PT + A G P PAGAR Sbjct: 997 APG----------APGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1037 Score = 36.2 bits (82), Expect = 0.054 Identities = 62/256 (24%), Positives = 80/256 (31%), Gaps = 39/256 (15%) Query: 104 GARGFSAPCCPPAAGGQVAAR---GKEPKPGGRVTLPALHLPKG-VCPHHPGKGSAGPSR 159 G G P PP GG AA+ G + K GG L + P G + P P + P Sbjct: 93 GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGG-AQLGVMQGPMGPMGPRGPPGPAGAPGP 151 Query: 160 RG----------------RGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGA 203 +G G R + + G+ E+ P G G Sbjct: 152 QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGT 211 Query: 204 SYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAAL 263 + GH LD +A V+ G+ G+ P GP G L Sbjct: 212 PGLPGVKGHRG----YPGLDGAKGEAGAPGVK--GESGS------PGENGSPGPMGPRGL 259 Query: 264 GEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPR----PA 319 +R T P RG G P GP P P P A GE P P Sbjct: 260 PGERG--RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 317 Query: 320 GARPRQAEIETDPETG 335 GA+ + E T G Sbjct: 318 GAQGPRGEPGTPGSPG 333 Score = 35.0 bits (79), Expect = 0.12 Identities = 65/249 (26%), Positives = 79/249 (31%), Gaps = 31/249 (12%) Query: 96 RVGRRRGSGARGFSA---PCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHH- 149 R G +GARG P PP G G PG G P+G Sbjct: 265 RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRG 324 Query: 150 -PGK-GSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPE 207 PG GS GP+ G G++ S G A PR +G TG P+ Sbjct: 325 EPGTPGSPGPAGASGNPGTDGIPGAK-GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 383 Query: 208 ELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEG-----PGGGAA 262 G +A + + Q GPAG E + PGG Sbjct: 384 GQTGEPG----------IAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP 433 Query: 263 LGEQRAGATTTPGSRR--RRRGAGRSAGWPHPGGPSR---PTRRNAPPARPDAAGEQCPR 317 +G G PG+R + G G P GPS P N P RP G R Sbjct: 434 IGPP--GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 491 Query: 318 PAGARPRQA 326 RP A Sbjct: 492 GLTGRPGDA 500 Score = 34.3 bits (77), Expect = 0.21 Identities = 65/234 (27%), Positives = 80/234 (34%), Gaps = 20/234 (8%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPGK----GSAG- 156 G G P PP G +G + PG G + P+G P PGK G AG Sbjct: 132 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP-PGPPGKPGDDGEAGK 190 Query: 157 PSRRG-RG----QRAKGFRGSE--MNSESRRGQTAAGREKHPRAGCSGEGETGASYPEEL 209 P + G RG Q A+GF G+ + RG K +GE+G+ Sbjct: 191 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS 250 Query: 210 HGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGH--GPAGRELEGPGGGAALGEQR 267 G L A A DG G GPAG PG A GE Sbjct: 251 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP-GFPGAPGAKGEAG 309 Query: 268 AGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGA 321 P + RG + G P P G S + P +AG P AGA Sbjct: 310 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAG--APGIAGA 361 Score = 32.3 bits (72), Expect = 0.78 Identities = 63/238 (26%), Positives = 73/238 (30%), Gaps = 31/238 (13%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPG-----GRVTLPALHLPKGVCPHHPGKGSAGPS 158 GARGF P G +G PG G P + G + G GP Sbjct: 204 GARGF------PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP- 256 Query: 159 RRGRGQRAKGFRGSEMNSESRRGQTA----------AGREKHPRA-GCSGE-GETGASYP 206 R G+R + + GQ AG P A G GE G TGA P Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316 Query: 207 EELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEG-PGGGAALGE 265 E G E A DG GA P G PG G Sbjct: 317 EGAQGPRGEP---GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 373 Query: 266 QRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARP 323 Q A T P + + G AG+ GP P P AGE+ R A P Sbjct: 374 QGA---TGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 428 Score = 28.9 bits (63), Expect = 8.7 Identities = 29/94 (30%), Positives = 33/94 (35%), Gaps = 11/94 (11%) Query: 97 VGRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAG 156 VG GA G P PP G+ G PG P P G P PG G Sbjct: 1100 VGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGN----PG---PPGP-PGPPGPGIDM 1151 Query: 157 PSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKH 190 + G G R K G + R Q A G +H Sbjct: 1152 SAFAGLGPREK---GPDPLQYMRADQAAGGLRQH 1182 >gi|197333868 T-box 2 [Homo sapiens] Length = 712 Score = 44.3 bits (103), Expect = 2e-04 Identities = 68/281 (24%), Positives = 95/281 (33%), Gaps = 41/281 (14%) Query: 60 KIHSLPYAKGGAPHWNSEFQTKAK-EIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAG 118 KI + P+AKG N + + + +PSL + R GA ++ C PP A Sbjct: 275 KIDNNPFAKGFRDTGNGRREKRKQLTLPSLRLYEEHCKPER---DGAESDASSCDPPPAR 331 Query: 119 GQVAARGKEPKP--------------------GGRVTLPALHLPKGVCPHHPGKGSAGPS 158 + G P P R++ P G P SA P+ Sbjct: 332 EPPTSPGAAPSPLRLHRARAEEKSCAADSDPEPERLSEERAGAPLG---RSPAPDSASPT 388 Query: 159 RRGRGQRAKGFRGSEMNSE-------------SRRGQTAAGREKHPRAGCSGEGETGASY 205 R +RA+ R E E S + A R K + EG+ Sbjct: 389 RLTEPERARERRSPERGKEPAESGGDGPFGLRSLEKERAEARRKDEGRKEAAEGKEQGLA 448 Query: 206 PEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGE 265 P + A L L LA + LH + G GA Q G+ GPG +A+G Sbjct: 449 PLVVQTDSASPLGAGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHPGQFTMGPGAFSAMGM 508 Query: 266 QRAGATTTPGSRRRRRGAGRSAGWPHPG-GPSRPTRRNAPP 305 A+ G G G +AG G GP+ A P Sbjct: 509 GHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAASTAAP 549 >gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] Length = 819 Score = 43.1 bits (100), Expect = 4e-04 Identities = 62/254 (24%), Positives = 97/254 (38%), Gaps = 55/254 (21%) Query: 92 PRWTRVGRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPG 151 PRW R + +G++ A AA V ++G E KP A Sbjct: 138 PRW-RAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGE-KPQKAAAAGA------------- 182 Query: 152 KGSAGPSRRGRGQRAKGF---RGSEMNSESRRGQTAAGREK-----HPRAGCSGEGETGA 203 K +G R RG +++G +G + ++SR G+T GR K P AG + G Sbjct: 183 KSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPAAGGAKSRRGGG 242 Query: 204 SYPEE--LHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGA 261 P++ G +A + G + + G ++L G A Sbjct: 243 KKPQKQRRRGQKAAT---------------------GGKSRVGKSRGGGDKKLRRQGQNA 281 Query: 262 AL-GEQRAGATTT---PGSRRRRRGAGRSAGWPHP---GGPSRPTRRNAPPARPDAAGEQ 314 AL G +R GA T P ++ R +S G +P G +P RR + AAG + Sbjct: 282 ALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTK 341 Query: 315 CPRPAGARPRQAEI 328 R G + + A + Sbjct: 342 --RGGGGQQKAAVV 353 Score = 41.2 bits (95), Expect = 0.002 Identities = 66/270 (24%), Positives = 90/270 (33%), Gaps = 37/270 (13%) Query: 95 TRVGRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGS 154 +R G+ RG + P PAAGG + RG GG+ P +G GK Sbjct: 212 SRFGKTRGGRRKKHRRP--KPAAGGAKSRRG-----GGKK--PQKQRRRGQKAATGGKSR 262 Query: 155 AGPSRRGRGQRAKGF-RGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHE 213 G SR G ++ + + + + RRG AG EK G G G G Sbjct: 263 VGKSRGGGDKKLRRQGQNAALAGAKRRGAATAG-EKPAAKGRGGRGPKSLGGQNPRWGRG 321 Query: 214 AESLLLEALDDLAHQAALHAVRLDGDEGALQVG------HGPAGRELEGPGGGAALGEQR 267 + AA G + A VG G++ AA + R Sbjct: 322 GKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSR 381 Query: 268 AGATTTPGSRRRRRGAGRS---------------AGWPHPGGPSRPTRRNAPPA-----R 307 G +RRG GR A P GG +P RR A + Sbjct: 382 GGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGK 441 Query: 308 PDAAGEQCPRPAGARPRQAEIETDPETGSD 337 + G + PR G + RQ E E+ D Sbjct: 442 SRSGGGKKPRRRGQKARQKAAEAGAESRGD 471 Score = 38.1 bits (87), Expect = 0.014 Identities = 82/354 (23%), Positives = 114/354 (32%), Gaps = 85/354 (24%) Query: 16 KKGESGQSGIGSVGRASQKTARRGKRKTNMLGVGIQICAPNLMWKIHSLPYAKGGAPHWN 75 K+G GQ VG S+K RR +K P + ++GG + Sbjct: 341 KRGGGGQQKAAVVGVKSRKKQRRRGKK------------PRRQKASAAGAKSRGGG---D 385 Query: 76 SEFQTKAKEIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAGGQVAARGKEPKP----G 131 + +AK PRW RR AP P GG R + PK G Sbjct: 386 KKGLREAKRRGDGRKKPRWQNPRRRAQK------APAAKPRGGGSKKPRRRGPKAAKSRG 439 Query: 132 GRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHP 191 G+ + G R RGQ+A+ + +E +ESR G GR+K Sbjct: 440 GK-----------------SRSGGGKKPRRRGQKARQ-KAAEAGAESR-GDKKQGRQKAS 480 Query: 192 RAGCSGEGETGASY----------PEELHGHEAESLLLEALDDLAHQAALHAV-----RL 236 AG G S+ E G +A + ++ + AV R+ Sbjct: 481 AAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRV 540 Query: 237 DGDE--------GALQVGHGPAGRELEGPGGG---------AALGEQRAGATTTPGSR-- 277 G + A HG G + GGG AA + R G PG + Sbjct: 541 GGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKA 600 Query: 278 -----RRRRGAGRSAGWPHPGGPSRPTRRNAPPAR--PDAAGEQCPRPAGARPR 324 + R G G W + R P R DAA + GA R Sbjct: 601 AAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSR 654 Score = 35.4 bits (80), Expect = 0.093 Identities = 83/346 (23%), Positives = 126/346 (36%), Gaps = 53/346 (15%) Query: 16 KKGESGQSGIGSVGRASQKTARRGKRKTNMLGV-----GIQICAPNLMWKIHSLPYAKG- 69 ++G+ + G S+ ++G++K + G G++ + +W+ A G Sbjct: 452 RRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGE 511 Query: 70 -----GAPHWNSEFQTKAKEIPSLHSVPRWTRVGRRRG-SGARGFSAPCCPPAAGGQVAA 123 GA + + K P++ +RVG + + +A GG + Sbjct: 512 KATAAGAKSRGRKQPRRQK--PAVAGAK--SRVGGSKSRQRQKAVAAGATSHGGGGNKQS 567 Query: 124 RG---KEPKPGGRVTLPALHLPKGVCPHHPG--KGSAG--PSRRGRG------QRAKGFR 170 RG +P+ G+ A +G PG K +AG SR G G Q+A G Sbjct: 568 RGGGGNKPRQWGQTAAAAK--TRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTG 625 Query: 171 GSEMNSESRRGQT-AAGREKHPRAGCSGEGETG--------ASYPEELHGHEAESLLLEA 221 RRGQ AA EK G + G G A+ E A EA Sbjct: 626 AKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEA 685 Query: 222 LDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRR 281 + A R DG + A VG P R + P LG+ R G G++ R Sbjct: 686 RKKPRRRRAKS--RGDGGQNAA-VGINPWQRRGKKP----RLGKSRGGG----GAKSRGS 734 Query: 282 GAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQAE 327 G +S G G SR ++ A G + R GA+ R E Sbjct: 735 GGAKSRG--SGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGE 778 Score = 28.9 bits (63), Expect = 8.7 Identities = 47/203 (23%), Positives = 69/203 (33%), Gaps = 30/203 (14%) Query: 22 QSGIGSVGRASQKTARRGKRKTNMLGVGIQICAPNLMWKIHSLPYAKGGA-PHWN----- 75 Q G+ ++ +K RRG++ A W + GG P W Sbjct: 619 QKAAGTGAKSRKKPWRRGQKDA---------AAAEKAWATGATSRGSGGKQPRWQKPAAA 669 Query: 76 ---SEFQTKAKEIPSLHSVPRWTRVGRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGG 132 S + PR R + RG G + + P G+ GK GG Sbjct: 670 GSESSAAAAVGQEAEARKKPRRRRA-KSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGG 728 Query: 133 ---RVTLPALHLPKGVCPHHPGKGSA-------GPSRRGRGQRAKGFRGSEMNSESRRGQ 182 R + A G GK +A G ++R RG AK G + + + Sbjct: 729 AKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKA 788 Query: 183 TAAGREKHPRA-GCSGEGETGAS 204 AAG +K PR G G+ A+ Sbjct: 789 AAAGGKKPPRVKSRGGRGQKAAA 811 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 42.7 bits (99), Expect = 6e-04 Identities = 69/243 (28%), Positives = 80/243 (32%), Gaps = 61/243 (25%) Query: 98 GRRRGSGARGFSAPCCP---PAAGGQVAARGKE-----PKPGGRVTLPALHLPKGVCPHH 149 G +GA GF+ P P P G+ G++ P P G P H P GV Sbjct: 837 GENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLK 896 Query: 150 PGKGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPR-AGCSGE----GETGAS 204 G+G+ GP A GF GS AGR P AG G GE G Sbjct: 897 GGRGTQGPPG------ATGFPGS------------AGRVGPPGPAGAPGPAGPLGEPGKE 938 Query: 205 YPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRE---------LE 255 P L G D +H GD G GP + + Sbjct: 939 GPPGLRG-----------DPGSHGRV-------GDRGPAGPPGGPGDKGDPGEDGQPGPD 980 Query: 256 GPGGGAALGEQRAGATTTPGSRRRRR--GAGRSAGWPHPGGPSRPTRRNAPPARPDAAGE 313 GP G A QR G PG R R G AG P GP+ T PP G Sbjct: 981 GPPGPAGTTGQR-GIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGS 1039 Query: 314 QCP 316 P Sbjct: 1040 NGP 1042 Score = 38.5 bits (88), Expect = 0.011 Identities = 60/224 (26%), Positives = 72/224 (32%), Gaps = 26/224 (11%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGP 157 G GARG P PP G +G EP P G V P G + +G GP Sbjct: 789 GTAGNDGARGLPGPLGPPGPAGPTGEKG-EPGPRGLVG------PPGSRGNPGSRGENGP 841 Query: 158 SRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESL 217 + A GF G + + + G E + G G + HG Sbjct: 842 T------GAVGFAGPQ-GPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPG 894 Query: 218 LLEALDDLAHQAALHAVRLDGDEGALQVG-HGPAGRELEGPGGGAALGEQRAGATTTPGS 276 L Q A G G +VG GPAG PG LGE G PG Sbjct: 895 L---KGGRGTQGPPGATGFPGSAG--RVGPPGPAG----APGPAGPLGE--PGKEGPPGL 943 Query: 277 RRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAG 320 R GR G P P + P + P PAG Sbjct: 944 RGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAG 987 Score = 38.1 bits (87), Expect = 0.014 Identities = 63/251 (25%), Positives = 79/251 (31%), Gaps = 38/251 (15%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKE--PKPGGRVTLPALHLPKGV--------CP 147 G+R G G P P G RG++ P P G LP P G P Sbjct: 639 GQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVP 698 Query: 148 HHPGK-GSAGPSRRGRGQRAK-GFRGSE--MNSESRRGQTAAGREKHPRAGCSGEGETGA 203 PG G GP RG+R G RG +G P+ G G Sbjct: 699 GDPGAVGPLGP----RGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGD 754 Query: 204 SYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEG----PGG 259 + P L G E + + + G++GA R L G PG Sbjct: 755 TGPPGLQGMPGERGIAGTPGPKGDRGGI------GEKGAEGTAGNDGARGLPGPLGPPGP 808 Query: 260 GAALGEQ----RAGATTTPGSR-----RRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDA 310 GE+ G PGSR R G + G+ P GP P P Sbjct: 809 AGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQ 868 Query: 311 AGEQ-CPRPAG 320 G+ P P G Sbjct: 869 KGDAGSPGPQG 879 Score = 35.4 bits (80), Expect = 0.093 Identities = 75/301 (24%), Positives = 96/301 (31%), Gaps = 52/301 (17%) Query: 96 RVGRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSA 155 +VG +G +G P PP + G V G E P G P G +G Sbjct: 1018 KVGPTGATGDKGPPGPVGPPGSNGPVGEPGPE-GPAGNDGTPG---RDGAVGERGDRGDP 1073 Query: 156 GPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAE 215 GP+ Q A G G + + GQ + P G+ G P+ G + + Sbjct: 1074 GPAGLPGSQGAPGTPG-PVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGD 1132 Query: 216 SLLLEALDDLAHQAALHAVRLDGDEGALQVGH-GPAGRELEG-PGGGAALGEQRAGATTT 273 H R GD G Q GH G G L+G PG GEQ + Sbjct: 1133 ----------------HGDR--GDRG--QKGHRGFTG--LQGLPGPPGPNGEQGSAGIPG 1170 Query: 274 P-GSRRRRRGAGRSAGWPHPG-----------------GPSRPTRRNAPPARPDAAGEQC 315 P G R G S +PG GP P PP P G Sbjct: 1171 PFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLT 1230 Query: 316 PRPAGARPRQAEIETD--PETGSDSFSTWTSYEFN---YARPKSHSSPLSTSRDPKSSYT 370 E D PE D + + + +A KS SS + T R P S Sbjct: 1231 AALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLKSLSSQIETMRSPDGSKK 1290 Query: 371 H 371 H Sbjct: 1291 H 1291 Score = 33.9 bits (76), Expect = 0.27 Identities = 70/252 (27%), Positives = 89/252 (35%), Gaps = 42/252 (16%) Query: 97 VGRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPG-KG 153 +G R G RG P A GQ A G KPG G + +P P +PG KG Sbjct: 335 LGPRGMPGERGRLGP---QGAPGQRGAHGMPGKPGPMGPLGIPG----SSGFPGNPGMKG 387 Query: 154 SAGPSRRGRGQRAKGFRGSEMNSESRRGQTA----AGREKHPRAGCSGEGETGASYPEEL 209 AGP+ G RG E + +RG+T G P A +G GA P Sbjct: 388 EAGPT---------GARGPE-GPQGQRGETGPPGPVGSPGLPGA-IGTDGTPGAKGPTGS 436 Query: 210 HGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVG--HGPAGRELE-GPGGGAALGEQ 266 G Q + + G G V G AG + E GP G Sbjct: 437 PGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHG------- 489 Query: 267 RAGATTTPGSRRRR--RGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARPR 324 G PG +R RG + G P P G R AP R + P P GA+ Sbjct: 490 IQGPIGPPGEEGKRGPRGDPGTVGPPGPVG-----ERGAPGNRGFPGSDGLPGPKGAQGE 544 Query: 325 QAEIETDPETGS 336 + + + GS Sbjct: 545 RGPVGSSGPKGS 556 Score = 30.8 bits (68), Expect = 2.3 Identities = 70/287 (24%), Positives = 89/287 (31%), Gaps = 57/287 (19%) Query: 103 SGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTL-----------PALHLPKGVCPHHPG 151 +G RG P PP + G RG + +PG R P P G P HPG Sbjct: 125 TGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGH-PSHPG 183 Query: 152 K-GSAGP-SRRGRGQRAKGFRGSEMN-------------------SESRRGQTAAGREKH 190 G + P S + G K GS++ + G T E Sbjct: 184 PDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPG 243 Query: 191 PRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPA 250 G G P G + E ++ + A G G + Sbjct: 244 DPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRG 303 Query: 251 GRELEGPGG--GAALGEQRAGATTT------------PGSRRR--------RRGAGRSAG 288 + LEGP G GA + AG T PG R R +RGA G Sbjct: 304 HKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPG 363 Query: 289 WPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQAEIETDPETG 335 P P GP + P P GE P GAR + ETG Sbjct: 364 KPGPMGPLGIPGSSGFPGNPGMKGE--AGPTGARGPEGPQGQRGETG 408 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 42.7 bits (99), Expect = 6e-04 Identities = 66/258 (25%), Positives = 77/258 (29%), Gaps = 52/258 (20%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG-----GRVTLPALHLPKGV------- 145 GR G RG P G+V RG + PG GRV P L +G Sbjct: 542 GRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEK 601 Query: 146 -------CPHHPG----KGSAGPSRRGRGQRAKG---------FRGSEMNSESRRGQTAA 185 P PG +G GPS Q KG GS + E +G+ A Sbjct: 602 GERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGA 661 Query: 186 GREKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQV 245 + + G G PE G L D+ + L G G V Sbjct: 662 PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGV 721 Query: 246 GHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPP 305 P GPGG L G PG G P P GP N PP Sbjct: 722 PGPP------GPGGSPGL----PGEIGFPGK----------PGPPGPTGPPGKDGPNGPP 761 Query: 306 ARPDAAGEQCPRPAGARP 323 P GE R P Sbjct: 762 GPPGTKGEPGERGEDGLP 779 Score = 41.6 bits (96), Expect = 0.001 Identities = 60/226 (26%), Positives = 72/226 (31%), Gaps = 41/226 (18%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGK-GSAGPSRRGR 162 G G P PP A GQ A G G P PG G+ GPS Sbjct: 889 GELGPQGPTGPPGAKGQEGAHGAPGAAGN--------------PGAPGHVGAPGPSGPPG 934 Query: 163 GQRAKGFRGSEMNSESRRGQTAAGREKHP----------------RAGCSGEGETGASYP 206 A G RG+ R + AAG E P G +GE G Sbjct: 935 SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGS 994 Query: 207 EELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQ 266 L G + + AL + GD GA + P R PG G A Sbjct: 995 PGLPGPLGTKAACGKVRG-SENCALGGQCVKGDRGAPGIPGSPGSR--GDPGIGVA---G 1048 Query: 267 RAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAG 312 G + PG +G+ S G P GP P R+ P P G Sbjct: 1049 PPGPSGPPGD----KGSPGSRGLPGFPGPQGPAGRDGAPGNPGERG 1090 Score = 31.6 bits (70), Expect = 1.3 Identities = 57/218 (26%), Positives = 73/218 (33%), Gaps = 28/218 (12%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAG-PSRRG- 161 G G + P PP G+ RG++ P G+ L +G+ KG AG P G Sbjct: 753 GKDGPNGPPGPPGTKGEPGERGEDGLP-GKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF 811 Query: 162 ---RGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSG--------------EGETGAS 204 RG++ E+ +G E P AG G GE G Sbjct: 812 PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGP-AGPPGLPGTTSLFTPHPRMPGEQGPK 870 Query: 205 YPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGAL----QVGHGPAGRELEGPGGG 260 + G E L +L Q G EGA G+ A + PG Sbjct: 871 GEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPS 930 Query: 261 AALGEQRA-GATTTPG--SRRRRRGAGRSAGWPHPGGP 295 G A G TPG R +GA G P P GP Sbjct: 931 GPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGP 968 Score = 30.4 bits (67), Expect = 3.0 Identities = 67/251 (26%), Positives = 83/251 (33%), Gaps = 44/251 (17%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPG-KGSAG 156 G G GF P PP G+ GKE P G+ P +G PG KG G Sbjct: 1351 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVP-GKPGEPGFKGERG----DPGIKGDKG 1405 Query: 157 PSRRGRGQRA-------KGFRGSEMNSESRRGQTAAGREKHPRA-----GCSGEG---ET 201 P G+GQ KG G M + G+ P G GE ET Sbjct: 1406 PP-GGKGQPGDPGIPGHKGHTGL-MGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMET 1463 Query: 202 GASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEG-----ALQVGHGPAGRE--- 253 +E G + E+ L L + + G G L GP G Sbjct: 1464 LRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRP 1523 Query: 254 ----LEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTR----RNAPP 305 LEGP G +R GA PG+ G G PG P +P ++ P Sbjct: 1524 GQGGLEGPSGPIGPKGER-GAKGDPGA----PGVGLRGEMGPPGIPGQPGEPGYAKDGLP 1578 Query: 306 ARPDAAGEQCP 316 P GE P Sbjct: 1579 GIPGPQGETGP 1589 >gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens] Length = 683 Score = 41.6 bits (96), Expect = 0.001 Identities = 36/105 (34%), Positives = 44/105 (41%), Gaps = 11/105 (10%) Query: 267 RAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQA 326 R G PG +R GAG AG P GGP T ++ + P+ AG P P G QA Sbjct: 30 RGGRRRQPGQQRPGPGAGAPAGRPEGGGPWARTEGSSLHSEPERAG-LGPAP-GTESPQA 87 Query: 327 EIETDPETGSDSFSTWTSYEFNYARPKSHSSPLSTSRDPKSSYTH 371 E TD +T + E RPK + P D S TH Sbjct: 88 EFWTDGQTEPAAAGLGVETE----RPKQKTEP-----DRSSLRTH 123 >gi|158854042 hypothetical protein LOC222183 [Homo sapiens] Length = 653 Score = 41.6 bits (96), Expect = 0.001 Identities = 72/321 (22%), Positives = 111/321 (34%), Gaps = 57/321 (17%) Query: 96 RVGRRRGSGAR--------GFSAPCCPPAAGGQVAARGKEP----KPGGRVTLPALHL-- 141 + G +R SG+R G+ +P +G + A G P P + + P+ + Sbjct: 288 KTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRD 347 Query: 142 -PKGVCPHHPGKGSAGPSRR------GRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAG 194 P P +G PS R GRG RA G G RR + R+ Sbjct: 348 KAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRR--------RRSRSS 399 Query: 195 CSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGREL 254 S G P + L A D G G GP Sbjct: 400 ASAPRRRGRRRPRPAPPRGSSRSLSRARSS-----------SDSGSGRGAPGPGPEPGSE 448 Query: 255 EGPGGGAALGEQR------AGATTTPGSRRRRRG-----AGRSAGWPHPGGPSRPTRRNA 303 G GG ++R A + +PG+ RR G + RS G PHP S + R+ Sbjct: 449 RGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPG-PHP--RSWSSSRSP 505 Query: 304 PPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARPKSHS-SPLSTS 362 +R +A ++ P+ + + + D + + + + E AR +S S SP+ Sbjct: 506 SKSRSRSAEKRPHSPSRSPSPKKPLSRDKD--GEGRARHSEAEATRARRRSRSYSPIRKR 563 Query: 363 RDPKSSYTHTHTHTHTEPAPV 383 R S+ T P+ Sbjct: 564 RRDSPSFMEPRRITSARKRPI 584 >gi|50843837 hypothetical protein LOC55701 [Homo sapiens] Length = 1519 Score = 41.6 bits (96), Expect = 0.001 Identities = 68/250 (27%), Positives = 93/250 (37%), Gaps = 34/250 (13%) Query: 103 SGARGFSAPCCP--------PAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGS 154 SG G +P P P G G E G V L + LP P +GS Sbjct: 207 SGPPGLPSPPLPEEALGTRSPGDGHNAPVEGPE---GEYVELLEVTLPVRGSPTD-AEGS 262 Query: 155 AGPSRRGRGQRAKGFRGSEMNSESRRG--QTAAGREKHPRAGCSGEGETGASYPEELHGH 212 G SR KG G + R Q G A GEG + + PE G Sbjct: 263 PGLSRVRTVPTRKGAGGKGRHRRHRAWMHQKGLGPRGQDGARPPGEGSSTGASPESPPGA 322 Query: 213 EA--ESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGA 270 EA E+ +LE + A + G L+ G G G+ EGP G Sbjct: 323 EAVPEAAVLEVSEPPAEAVGEASGSCPLRPGELR-GGGGGGQGAEGPPG--------TPR 373 Query: 271 TTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQC----PRPAGARPRQA 326 T G+RR++R AGR A GG S P +P + DA+ ++ P P+ + + Sbjct: 374 RTGKGNRRKKRAAGRGA--LSRGGDSAPL---SPGDKEDASHQEALGNLPSPSEHKLPEC 428 Query: 327 EIETDPETGS 336 + + GS Sbjct: 429 HLVKEEYEGS 438 >gi|169168886 PREDICTED: hypothetical protein [Homo sapiens] Length = 278 Score = 41.2 bits (95), Expect = 0.002 Identities = 55/213 (25%), Positives = 71/213 (33%), Gaps = 15/213 (7%) Query: 150 PGKGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAG--CSGEGETGASYPE 207 P K PS G + +G +E+ R T R R G +G G A Sbjct: 33 PPKMQGAPSLAGEEEGKRGVGDAEV----RHWGTLTSRASGMRVGIWAAGGGLAAAGERN 88 Query: 208 ELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQR 267 + S + ++ A A+ A L G L VG G +L G AA Q Sbjct: 89 SVRAVSFSSGRVGVREEAAGHLAVGAAGLTGAHADLAVGRGAELAQLLGADAAAAAAVQH 148 Query: 268 AGATTTPGSRRRRRGAGRSAG-------WPHPGGPSRPTRRNAPPARPDAAGEQCPRPAG 320 RR R R A GG R +A P RP Q P AG Sbjct: 149 EAHARRAARRRLVRAPARPAAVLADGRLQGGQGGQRRSVGAHALPGRPRVPPWQPPAAAG 208 Query: 321 ARPR--QAEIETDPETGSDSFSTWTSYEFNYAR 351 A AE E D E +D T + ++ R Sbjct: 209 APGAYPAAEGEEDHEGDADGAHTGGGHGWHCGR 241 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 41.2 bits (95), Expect = 0.002 Identities = 54/220 (24%), Positives = 73/220 (33%), Gaps = 14/220 (6%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGP 157 GR G G P PP G+ +G+ PG + T KG H G GP Sbjct: 974 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT-------KGNKGEHGPPGPPGP 1026 Query: 158 SRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESL 217 A G G E + +G A ++ R G G G + E+ Sbjct: 1027 IGPVGQPGAAGADG-EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1085 Query: 218 LLEALDDLAHQAALHAVRLDGDEGAL----QVGH-GPAGRELEGPGGGAALGEQRAGATT 272 + + +G +G VG+ GP G + E PG + G Q Sbjct: 1086 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE-PGESGSPGIQGEPGVK 1144 Query: 273 TPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAG 312 P R +G G P P GP PT + P P G Sbjct: 1145 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1184 Score = 39.7 bits (91), Expect = 0.005 Identities = 66/236 (27%), Positives = 76/236 (32%), Gaps = 46/236 (19%) Query: 103 SGARGFSAPCCPPAAGGQVAARGKEPKPG-----------GRVTLPALHLPKGVCPHHPG 151 SG RG P P G A GK G G LP P G PG Sbjct: 748 SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF----PG 803 Query: 152 -KGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGE----GETGASYP 206 KG GP + G RG E+ + + G P+ G +GE GE G P Sbjct: 804 PKGPPGPPGKDGLPGHPGQRG-EVGFQGKTGPPGPPGVVGPQ-GAAGETGPMGERGHPGP 861 Query: 207 EELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAG-------RELEGPGG 259 G + L A + D GPAG R L G G Sbjct: 862 PGPPGEQG----------LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 911 Query: 260 GAAL-GEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQ 314 G L G + P RGA S GGP P R P P AAGE+ Sbjct: 912 GPGLKGNEGPSGPPGPAGSPGERGAAGS------GGPIGPPGRPGPQGPPGAAGEK 961 Score = 38.1 bits (87), Expect = 0.014 Identities = 60/230 (26%), Positives = 77/230 (33%), Gaps = 39/230 (16%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPG----KGSAGPSR 159 G +G + P P G + +GK PG P +PG KGS G Sbjct: 686 GPKGRTGPTGDPGPPGLMGEKGKLGVPG--------------LPGYPGRQGPKGSLGFPG 731 Query: 160 RGRGQRAKGFRGSEMNSESR--RGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESL 217 KG RG S R RG T ++ PR G G S + HG E Sbjct: 732 FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 791 Query: 218 LLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRE-LEG-PGGGAALGEQ-RAGATTTP 274 L G +G GP G++ L G PG +G Q + G P Sbjct: 792 L---------PGPQGPNGFPGPKGP----PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPP 838 Query: 275 GSRRRRRGAGRSAGWP---HPGGPSRPTRRNAPPARPDAAGEQCPRPAGA 321 G + AG + HPG P P + P + P P GA Sbjct: 839 GVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 888 Score = 36.2 bits (82), Expect = 0.054 Identities = 70/276 (25%), Positives = 92/276 (33%), Gaps = 66/276 (23%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGK-----------EPKPGGRVTLPALHLPKGV- 145 G+R G +G + P PP G A G+ P P G LP +G Sbjct: 821 GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 880 Query: 146 ----CPHHPGK-GSAG----PSRRGRGQRA--KGFRGSE--------MNSESRRGQTAAG 186 P PGK G AG P RG A G +G+E S RG +G Sbjct: 881 GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG 940 Query: 187 REKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVG 246 P +G GA+ + + G + + G +G Sbjct: 941 GPIGPPGRPGPQGPPGAAGEKGVPGEKG------------------PIGPTGRDGV---- 978 Query: 247 HGPAGRELEGPGG--GAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAP 304 GP G L GP G G A + G PG + + G G P P GP P Sbjct: 979 QGPVG--LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEH-GPPGPPGPI------GP 1029 Query: 305 PARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFS 340 +P AAG GAR Q + G+ F+ Sbjct: 1030 VGQPGAAG--ADGEPGARGPQGHFGAKGDEGTRGFN 1063 Score = 35.8 bits (81), Expect = 0.071 Identities = 66/255 (25%), Positives = 83/255 (32%), Gaps = 40/255 (15%) Query: 103 SGARGFSAPCCPPAAGGQVAARGK--------------EPKPGGRVTLP---ALHLPKGV 145 SG RG P PP G RG EP P G+ P L P+G Sbjct: 520 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 579 Query: 146 CPHHPGKGSAG----PSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGET 201 H KG G P G G G E ++ Q +G + P G Sbjct: 580 IGPHGEKGPQGKPGLPGMPG-SDGPPGHPGKEGPPGTKGNQGPSG-PQGPLGYPGPRGVK 637 Query: 202 GASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGA 261 G L GH+ E + + + GD G + V P R +GP G Sbjct: 638 GVDGIRGLKGHKGEK------GEDGFPGFKGDIGVKGDRGEVGV---PGSRGEDGPEG-- 686 Query: 262 ALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSR--PTRRNAPPARPDAAGEQCPRPA 319 + R G T PG G+ PG P R P P P A+GE+ R Sbjct: 687 --PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 744 Query: 320 GAR--PRQAEIETDP 332 + PR T P Sbjct: 745 SGKSGPRGERGPTGP 759 Score = 35.8 bits (81), Expect = 0.071 Identities = 52/200 (26%), Positives = 69/200 (34%), Gaps = 34/200 (17%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPG-KGS 154 GR+ G GA+G P G V G KPG G LP +G PG G Sbjct: 1244 GRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG----RPGATGQ 1299 Query: 155 AGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEA 214 AGP G RG + ++ +G P +G+ G P+ G + Sbjct: 1300 AGPPGPVGPPGLPGLRG-DAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKG 1358 Query: 215 ESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTP 274 E + + G G + G GP G L GP G + A T P Sbjct: 1359 E------------------MGIPGASGPIGPG-GPPG--LPGPA-----GPKGAKGATGP 1392 Query: 275 GSRRRRRGAGRSAGWPHPGG 294 G + +G G P P G Sbjct: 1393 GGPKGEKGVQGPPGHPGPPG 1412 Score = 34.7 bits (78), Expect = 0.16 Identities = 57/241 (23%), Positives = 73/241 (30%), Gaps = 28/241 (11%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHH--PG-K 152 G G G +G P PP G RG G G P P G PG K Sbjct: 908 GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEK 967 Query: 153 GSAGPSRRGRGQRAKGFRGSE-----MNSESRRGQTAAGREKHPRAGCSGEGETGASYPE 207 G GP+ R Q G G + +G+ +K + +GE G P Sbjct: 968 GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGN---KGEHGPPGPP 1024 Query: 208 ELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEG-PGGGAALGEQ 266 G + A + + GDEG P L+G PG GE Sbjct: 1025 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1084 Query: 267 R-AGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQ 325 G PG P P GP+ P + P P G P P + Sbjct: 1085 GDVGPMGPPGP-------------PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGE 1131 Query: 326 A 326 + Sbjct: 1132 S 1132 Score = 33.9 bits (76), Expect = 0.27 Identities = 59/249 (23%), Positives = 83/249 (33%), Gaps = 43/249 (17%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAA------RGKEPKPG--GRVTLPALHLPKGVCPHH 149 G + G GF PP GG RG++ +PG G + P G Sbjct: 1175 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234 Query: 150 PGKGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTA-AGREKHP----------------R 192 GS G R G+ AKG G+ + + + G AG P R Sbjct: 1235 GPAGSPGSEGRQGGKGAKGDPGA-IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR 1293 Query: 193 AGCSGE-GETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEG-----ALQVG 246 G +G+ G G P L G ++ A + H + + G++G L Sbjct: 1294 PGATGQAGPPGPVGPPGLPGLRGDA---GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1350 Query: 247 HGPAGR--ELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAP 304 G G+ E+ PG +G P + +GA PGGP P Sbjct: 1351 QGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGA------TGPGGPKGEKGVQGP 1404 Query: 305 PARPDAAGE 313 P P GE Sbjct: 1405 PGHPGPPGE 1413 Score = 33.1 bits (74), Expect = 0.46 Identities = 64/257 (24%), Positives = 83/257 (32%), Gaps = 34/257 (13%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAG- 156 G+ G +G P P G RG + G R G+ H KG G Sbjct: 608 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIR----------GLKGHKGEKGEDGF 657 Query: 157 PSRRG----RGQRAK----GFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEE 208 P +G +G R + G RG + E +G+T + P +G+ G Sbjct: 658 PGFKGDIGVKGDRGEVGVPGSRGED-GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG 716 Query: 209 LHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAG-RELEGPGGGA----AL 263 G + L A L G G + GP G R GP G A Sbjct: 717 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP-RGERGPTGPRGQRGPRGATGKSGAK 775 Query: 264 GEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGE-------QCP 316 G P R G G+P P GP P ++ P P GE P Sbjct: 776 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPP 835 Query: 317 RPAG-ARPRQAEIETDP 332 P G P+ A ET P Sbjct: 836 GPPGVVGPQGAAGETGP 852 Score = 30.8 bits (68), Expect = 2.3 Identities = 55/228 (24%), Positives = 74/228 (32%), Gaps = 26/228 (11%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPGKGSA 155 G + G RGF+ P P G G++ + G G + P P+G + G Sbjct: 1052 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQ 1111 Query: 156 GPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAE 215 GP G +G S S Q G K PR +GE+G G + Sbjct: 1112 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPG-VKGPRGERGEKGESGQPGEPGPPGPKGP 1170 Query: 216 SLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPG 275 + D + V GD G G GP G++ GA G PG Sbjct: 1171 T------GDDGPKGNPGPVGFPGDPGPPGEG-GPRGQD------GAKGDRGEDGEPGQPG 1217 Query: 276 SRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARP 323 S G GP P + P P + G Q + A P Sbjct: 1218 S----------PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1255 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 41.2 bits (95), Expect = 0.002 Identities = 54/220 (24%), Positives = 73/220 (33%), Gaps = 14/220 (6%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGP 157 GR G G P PP G+ +G+ PG + T KG H G GP Sbjct: 953 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT-------KGNKGEHGPPGPPGP 1005 Query: 158 SRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESL 217 A G G E + +G A ++ R G G G + E+ Sbjct: 1006 IGPVGQPGAAGADG-EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1064 Query: 218 LLEALDDLAHQAALHAVRLDGDEGAL----QVGH-GPAGRELEGPGGGAALGEQRAGATT 272 + + +G +G VG+ GP G + E PG + G Q Sbjct: 1065 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE-PGESGSPGIQGEPGVK 1123 Query: 273 TPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAG 312 P R +G G P P GP PT + P P G Sbjct: 1124 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1163 Score = 39.7 bits (91), Expect = 0.005 Identities = 66/236 (27%), Positives = 76/236 (32%), Gaps = 46/236 (19%) Query: 103 SGARGFSAPCCPPAAGGQVAARGKEPKPG-----------GRVTLPALHLPKGVCPHHPG 151 SG RG P P G A GK G G LP P G PG Sbjct: 727 SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF----PG 782 Query: 152 -KGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGE----GETGASYP 206 KG GP + G RG E+ + + G P+ G +GE GE G P Sbjct: 783 PKGPPGPPGKDGLPGHPGQRG-EVGFQGKTGPPGPPGVVGPQ-GAAGETGPMGERGHPGP 840 Query: 207 EELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAG-------RELEGPGG 259 G + L A + D GPAG R L G G Sbjct: 841 PGPPGEQG----------LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 890 Query: 260 GAAL-GEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQ 314 G L G + P RGA S GGP P R P P AAGE+ Sbjct: 891 GPGLKGNEGPSGPPGPAGSPGERGAAGS------GGPIGPPGRPGPQGPPGAAGEK 940 Score = 38.1 bits (87), Expect = 0.014 Identities = 60/230 (26%), Positives = 77/230 (33%), Gaps = 39/230 (16%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPG----KGSAGPSR 159 G +G + P P G + +GK PG P +PG KGS G Sbjct: 665 GPKGRTGPTGDPGPPGLMGEKGKLGVPG--------------LPGYPGRQGPKGSLGFPG 710 Query: 160 RGRGQRAKGFRGSEMNSESR--RGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESL 217 KG RG S R RG T ++ PR G G S + HG E Sbjct: 711 FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 770 Query: 218 LLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRE-LEG-PGGGAALGEQ-RAGATTTP 274 L G +G GP G++ L G PG +G Q + G P Sbjct: 771 L---------PGPQGPNGFPGPKGP----PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPP 817 Query: 275 GSRRRRRGAGRSAGWP---HPGGPSRPTRRNAPPARPDAAGEQCPRPAGA 321 G + AG + HPG P P + P + P P GA Sbjct: 818 GVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 867 Score = 36.2 bits (82), Expect = 0.054 Identities = 70/276 (25%), Positives = 92/276 (33%), Gaps = 66/276 (23%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGK-----------EPKPGGRVTLPALHLPKGV- 145 G+R G +G + P PP G A G+ P P G LP +G Sbjct: 800 GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 859 Query: 146 ----CPHHPGK-GSAG----PSRRGRGQRA--KGFRGSE--------MNSESRRGQTAAG 186 P PGK G AG P RG A G +G+E S RG +G Sbjct: 860 GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG 919 Query: 187 REKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVG 246 P +G GA+ + + G + + G +G Sbjct: 920 GPIGPPGRPGPQGPPGAAGEKGVPGEKG------------------PIGPTGRDGV---- 957 Query: 247 HGPAGRELEGPGG--GAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAP 304 GP G L GP G G A + G PG + + G G P P GP P Sbjct: 958 QGPVG--LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEH-GPPGPPGPI------GP 1008 Query: 305 PARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFS 340 +P AAG GAR Q + G+ F+ Sbjct: 1009 VGQPGAAG--ADGEPGARGPQGHFGAKGDEGTRGFN 1042 Score = 35.8 bits (81), Expect = 0.071 Identities = 66/255 (25%), Positives = 83/255 (32%), Gaps = 40/255 (15%) Query: 103 SGARGFSAPCCPPAAGGQVAARGK--------------EPKPGGRVTLP---ALHLPKGV 145 SG RG P PP G RG EP P G+ P L P+G Sbjct: 499 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 558 Query: 146 CPHHPGKGSAG----PSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGET 201 H KG G P G G G E ++ Q +G + P G Sbjct: 559 IGPHGEKGPQGKPGLPGMPG-SDGPPGHPGKEGPPGTKGNQGPSG-PQGPLGYPGPRGVK 616 Query: 202 GASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGA 261 G L GH+ E + + + GD G + V P R +GP G Sbjct: 617 GVDGIRGLKGHKGEK------GEDGFPGFKGDIGVKGDRGEVGV---PGSRGEDGPEG-- 665 Query: 262 ALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSR--PTRRNAPPARPDAAGEQCPRPA 319 + R G T PG G+ PG P R P P P A+GE+ R Sbjct: 666 --PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723 Query: 320 GAR--PRQAEIETDP 332 + PR T P Sbjct: 724 SGKSGPRGERGPTGP 738 Score = 35.8 bits (81), Expect = 0.071 Identities = 52/200 (26%), Positives = 69/200 (34%), Gaps = 34/200 (17%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPG-KGS 154 GR+ G GA+G P G V G KPG G LP +G PG G Sbjct: 1223 GRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG----RPGATGQ 1278 Query: 155 AGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEA 214 AGP G RG + ++ +G P +G+ G P+ G + Sbjct: 1279 AGPPGPVGPPGLPGLRG-DAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKG 1337 Query: 215 ESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTP 274 E + + G G + G GP G L GP G + A T P Sbjct: 1338 E------------------MGIPGASGPIGPG-GPPG--LPGPA-----GPKGAKGATGP 1371 Query: 275 GSRRRRRGAGRSAGWPHPGG 294 G + +G G P P G Sbjct: 1372 GGPKGEKGVQGPPGHPGPPG 1391 Score = 34.7 bits (78), Expect = 0.16 Identities = 57/241 (23%), Positives = 73/241 (30%), Gaps = 28/241 (11%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHH--PG-K 152 G G G +G P PP G RG G G P P G PG K Sbjct: 887 GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEK 946 Query: 153 GSAGPSRRGRGQRAKGFRGSE-----MNSESRRGQTAAGREKHPRAGCSGEGETGASYPE 207 G GP+ R Q G G + +G+ +K + +GE G P Sbjct: 947 GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGN---KGEHGPPGPP 1003 Query: 208 ELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEG-PGGGAALGEQ 266 G + A + + GDEG P L+G PG GE Sbjct: 1004 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1063 Query: 267 R-AGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQ 325 G PG P P GP+ P + P P G P P + Sbjct: 1064 GDVGPMGPPGP-------------PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGE 1110 Query: 326 A 326 + Sbjct: 1111 S 1111 Score = 33.9 bits (76), Expect = 0.27 Identities = 59/249 (23%), Positives = 83/249 (33%), Gaps = 43/249 (17%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAA------RGKEPKPG--GRVTLPALHLPKGVCPHH 149 G + G GF PP GG RG++ +PG G + P G Sbjct: 1154 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213 Query: 150 PGKGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTA-AGREKHP----------------R 192 GS G R G+ AKG G+ + + + G AG P R Sbjct: 1214 GPAGSPGSEGRQGGKGAKGDPGA-IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR 1272 Query: 193 AGCSGE-GETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEG-----ALQVG 246 G +G+ G G P L G ++ A + H + + G++G L Sbjct: 1273 PGATGQAGPPGPVGPPGLPGLRGDA---GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1329 Query: 247 HGPAGR--ELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAP 304 G G+ E+ PG +G P + +GA PGGP P Sbjct: 1330 QGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGA------TGPGGPKGEKGVQGP 1383 Query: 305 PARPDAAGE 313 P P GE Sbjct: 1384 PGHPGPPGE 1392 Score = 33.1 bits (74), Expect = 0.46 Identities = 64/257 (24%), Positives = 83/257 (32%), Gaps = 34/257 (13%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAG- 156 G+ G +G P P G RG + G R G+ H KG G Sbjct: 587 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIR----------GLKGHKGEKGEDGF 636 Query: 157 PSRRG----RGQRAK----GFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEE 208 P +G +G R + G RG + E +G+T + P +G+ G Sbjct: 637 PGFKGDIGVKGDRGEVGVPGSRGED-GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG 695 Query: 209 LHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAG-RELEGPGGGA----AL 263 G + L A L G G + GP G R GP G A Sbjct: 696 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP-RGERGPTGPRGQRGPRGATGKSGAK 754 Query: 264 GEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGE-------QCP 316 G P R G G+P P GP P ++ P P GE P Sbjct: 755 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPP 814 Query: 317 RPAG-ARPRQAEIETDP 332 P G P+ A ET P Sbjct: 815 GPPGVVGPQGAAGETGP 831 Score = 30.8 bits (68), Expect = 2.3 Identities = 55/228 (24%), Positives = 74/228 (32%), Gaps = 26/228 (11%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPGKGSA 155 G + G RGF+ P P G G++ + G G + P P+G + G Sbjct: 1031 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQ 1090 Query: 156 GPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAE 215 GP G +G S S Q G K PR +GE+G G + Sbjct: 1091 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPG-VKGPRGERGEKGESGQPGEPGPPGPKGP 1149 Query: 216 SLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPG 275 + D + V GD G G GP G++ GA G PG Sbjct: 1150 T------GDDGPKGNPGPVGFPGDPGPPGEG-GPRGQD------GAKGDRGEDGEPGQPG 1196 Query: 276 SRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARP 323 S G GP P + P P + G Q + A P Sbjct: 1197 S----------PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1234 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 41.2 bits (95), Expect = 0.002 Identities = 54/220 (24%), Positives = 73/220 (33%), Gaps = 14/220 (6%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGP 157 GR G G P PP G+ +G+ PG + T KG H G GP Sbjct: 1060 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT-------KGNKGEHGPPGPPGP 1112 Query: 158 SRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESL 217 A G G E + +G A ++ R G G G + E+ Sbjct: 1113 IGPVGQPGAAGADG-EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1171 Query: 218 LLEALDDLAHQAALHAVRLDGDEGAL----QVGH-GPAGRELEGPGGGAALGEQRAGATT 272 + + +G +G VG+ GP G + E PG + G Q Sbjct: 1172 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE-PGESGSPGIQGEPGVK 1230 Query: 273 TPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAG 312 P R +G G P P GP PT + P P G Sbjct: 1231 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1270 Score = 39.7 bits (91), Expect = 0.005 Identities = 66/236 (27%), Positives = 76/236 (32%), Gaps = 46/236 (19%) Query: 103 SGARGFSAPCCPPAAGGQVAARGKEPKPG-----------GRVTLPALHLPKGVCPHHPG 151 SG RG P P G A GK G G LP P G PG Sbjct: 834 SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF----PG 889 Query: 152 -KGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGE----GETGASYP 206 KG GP + G RG E+ + + G P+ G +GE GE G P Sbjct: 890 PKGPPGPPGKDGLPGHPGQRG-EVGFQGKTGPPGPPGVVGPQ-GAAGETGPMGERGHPGP 947 Query: 207 EELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAG-------RELEGPGG 259 G + L A + D GPAG R L G G Sbjct: 948 PGPPGEQG----------LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 997 Query: 260 GAAL-GEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQ 314 G L G + P RGA S GGP P R P P AAGE+ Sbjct: 998 GPGLKGNEGPSGPPGPAGSPGERGAAGS------GGPIGPPGRPGPQGPPGAAGEK 1047 Score = 38.1 bits (87), Expect = 0.014 Identities = 60/230 (26%), Positives = 77/230 (33%), Gaps = 39/230 (16%) Query: 104 GARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPG----KGSAGPSR 159 G +G + P P G + +GK PG P +PG KGS G Sbjct: 772 GPKGRTGPTGDPGPPGLMGEKGKLGVPG--------------LPGYPGRQGPKGSLGFPG 817 Query: 160 RGRGQRAKGFRGSEMNSESR--RGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESL 217 KG RG S R RG T ++ PR G G S + HG E Sbjct: 818 FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 877 Query: 218 LLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRE-LEG-PGGGAALGEQ-RAGATTTP 274 L G +G GP G++ L G PG +G Q + G P Sbjct: 878 L---------PGPQGPNGFPGPKGP----PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPP 924 Query: 275 GSRRRRRGAGRSAGWP---HPGGPSRPTRRNAPPARPDAAGEQCPRPAGA 321 G + AG + HPG P P + P + P P GA Sbjct: 925 GVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 974 Score = 36.2 bits (82), Expect = 0.054 Identities = 70/276 (25%), Positives = 92/276 (33%), Gaps = 66/276 (23%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGK-----------EPKPGGRVTLPALHLPKGV- 145 G+R G +G + P PP G A G+ P P G LP +G Sbjct: 907 GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 966 Query: 146 ----CPHHPGK-GSAG----PSRRGRGQRA--KGFRGSE--------MNSESRRGQTAAG 186 P PGK G AG P RG A G +G+E S RG +G Sbjct: 967 GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG 1026 Query: 187 REKHPRAGCSGEGETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVG 246 P +G GA+ + + G + + G +G Sbjct: 1027 GPIGPPGRPGPQGPPGAAGEKGVPGEKG------------------PIGPTGRDGV---- 1064 Query: 247 HGPAGRELEGPGG--GAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAP 304 GP G L GP G G A + G PG + + G G P P GP P Sbjct: 1065 QGPVG--LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEH-GPPGPPGPI------GP 1115 Query: 305 PARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFS 340 +P AAG GAR Q + G+ F+ Sbjct: 1116 VGQPGAAG--ADGEPGARGPQGHFGAKGDEGTRGFN 1149 Score = 35.8 bits (81), Expect = 0.071 Identities = 66/255 (25%), Positives = 83/255 (32%), Gaps = 40/255 (15%) Query: 103 SGARGFSAPCCPPAAGGQVAARGK--------------EPKPGGRVTLP---ALHLPKGV 145 SG RG P PP G RG EP P G+ P L P+G Sbjct: 606 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 665 Query: 146 CPHHPGKGSAG----PSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGET 201 H KG G P G G G E ++ Q +G + P G Sbjct: 666 IGPHGEKGPQGKPGLPGMPG-SDGPPGHPGKEGPPGTKGNQGPSG-PQGPLGYPGPRGVK 723 Query: 202 GASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGA 261 G L GH+ E + + + GD G + V P R +GP G Sbjct: 724 GVDGIRGLKGHKGEK------GEDGFPGFKGDIGVKGDRGEVGV---PGSRGEDGPEG-- 772 Query: 262 ALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSR--PTRRNAPPARPDAAGEQCPRPA 319 + R G T PG G+ PG P R P P P A+GE+ R Sbjct: 773 --PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 830 Query: 320 GAR--PRQAEIETDP 332 + PR T P Sbjct: 831 SGKSGPRGERGPTGP 845 Score = 35.8 bits (81), Expect = 0.071 Identities = 52/200 (26%), Positives = 69/200 (34%), Gaps = 34/200 (17%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPG-KGS 154 GR+ G GA+G P G V G KPG G LP +G PG G Sbjct: 1330 GRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG----RPGATGQ 1385 Query: 155 AGPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEA 214 AGP G RG + ++ +G P +G+ G P+ G + Sbjct: 1386 AGPPGPVGPPGLPGLRG-DAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKG 1444 Query: 215 ESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTP 274 E + + G G + G GP G L GP G + A T P Sbjct: 1445 E------------------MGIPGASGPIGPG-GPPG--LPGPA-----GPKGAKGATGP 1478 Query: 275 GSRRRRRGAGRSAGWPHPGG 294 G + +G G P P G Sbjct: 1479 GGPKGEKGVQGPPGHPGPPG 1498 Score = 34.7 bits (78), Expect = 0.16 Identities = 57/241 (23%), Positives = 73/241 (30%), Gaps = 28/241 (11%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHH--PG-K 152 G G G +G P PP G RG G G P P G PG K Sbjct: 994 GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEK 1053 Query: 153 GSAGPSRRGRGQRAKGFRGSE-----MNSESRRGQTAAGREKHPRAGCSGEGETGASYPE 207 G GP+ R Q G G + +G+ +K + +GE G P Sbjct: 1054 GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGN---KGEHGPPGPP 1110 Query: 208 ELHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEG-PGGGAALGEQ 266 G + A + + GDEG P L+G PG GE Sbjct: 1111 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1170 Query: 267 R-AGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQ 325 G PG P P GP+ P + P P G P P + Sbjct: 1171 GDVGPMGPPGP-------------PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGE 1217 Query: 326 A 326 + Sbjct: 1218 S 1218 Score = 33.9 bits (76), Expect = 0.27 Identities = 59/249 (23%), Positives = 83/249 (33%), Gaps = 43/249 (17%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAA------RGKEPKPG--GRVTLPALHLPKGVCPHH 149 G + G GF PP GG RG++ +PG G + P G Sbjct: 1261 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320 Query: 150 PGKGSAGPSRRGRGQRAKGFRGSEMNSESRRGQTA-AGREKHP----------------R 192 GS G R G+ AKG G+ + + + G AG P R Sbjct: 1321 GPAGSPGSEGRQGGKGAKGDPGA-IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR 1379 Query: 193 AGCSGE-GETGASYPEELHGHEAESLLLEALDDLAHQAALHAVRLDGDEG-----ALQVG 246 G +G+ G G P L G ++ A + H + + G++G L Sbjct: 1380 PGATGQAGPPGPVGPPGLPGLRGDA---GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1436 Query: 247 HGPAGR--ELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAP 304 G G+ E+ PG +G P + +GA PGGP P Sbjct: 1437 QGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGA------TGPGGPKGEKGVQGP 1490 Query: 305 PARPDAAGE 313 P P GE Sbjct: 1491 PGHPGPPGE 1499 Score = 33.1 bits (74), Expect = 0.46 Identities = 64/257 (24%), Positives = 83/257 (32%), Gaps = 34/257 (13%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPGGRVTLPALHLPKGVCPHHPGKGSAG- 156 G+ G +G P P G RG + G R G+ H KG G Sbjct: 694 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIR----------GLKGHKGEKGEDGF 743 Query: 157 PSRRG----RGQRAK----GFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEE 208 P +G +G R + G RG + E +G+T + P +G+ G Sbjct: 744 PGFKGDIGVKGDRGEVGVPGSRGED-GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG 802 Query: 209 LHGHEAESLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAG-RELEGPGGGA----AL 263 G + L A L G G + GP G R GP G A Sbjct: 803 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP-RGERGPTGPRGQRGPRGATGKSGAK 861 Query: 264 GEQRAGATTTPGSRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGE-------QCP 316 G P R G G+P P GP P ++ P P GE P Sbjct: 862 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPP 921 Query: 317 RPAG-ARPRQAEIETDP 332 P G P+ A ET P Sbjct: 922 GPPGVVGPQGAAGETGP 938 Score = 30.8 bits (68), Expect = 2.3 Identities = 55/228 (24%), Positives = 74/228 (32%), Gaps = 26/228 (11%) Query: 98 GRRRGSGARGFSAPCCPPAAGGQVAARGKEPKPG--GRVTLPALHLPKGVCPHHPGKGSA 155 G + G RGF+ P P G G++ + G G + P P+G + G Sbjct: 1138 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQ 1197 Query: 156 GPSRRGRGQRAKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAE 215 GP G +G S S Q G K PR +GE+G G + Sbjct: 1198 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPG-VKGPRGERGEKGESGQPGEPGPPGPKGP 1256 Query: 216 SLLLEALDDLAHQAALHAVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPG 275 + D + V GD G G GP G++ GA G PG Sbjct: 1257 T------GDDGPKGNPGPVGFPGDPGPPGEG-GPRGQD------GAKGDRGEDGEPGQPG 1303 Query: 276 SRRRRRGAGRSAGWPHPGGPSRPTRRNAPPARPDAAGEQCPRPAGARP 323 S G GP P + P P + G Q + A P Sbjct: 1304 S----------PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1341 >gi|23397672 homeobox D4 [Homo sapiens] Length = 255 Score = 40.4 bits (93), Expect = 0.003 Identities = 43/138 (31%), Positives = 55/138 (39%), Gaps = 13/138 (9%) Query: 238 GDEGALQVGHGPAGRELEGPG--GGAALGEQR-AGATTTPGSRRRRRGAGRSAGWP--HP 292 G++GA G G G + + PG GEQ G+ PGS RG G+ G P H Sbjct: 30 GEQGADYYGGGAQGADFQPPGLYPRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGGHY 89 Query: 293 GGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARP 352 P P APPA P A P P GAR P +G+ Y + Sbjct: 90 AAPGEPC--PAPPAPPPA-----PLP-GARAYSQSDPKQPPSGTALKQPAVVYPWMKKVH 141 Query: 353 KSHSSPLSTSRDPKSSYT 370 + +P T +PK S T Sbjct: 142 VNSVNPNYTGGEPKRSRT 159 >gi|239751026 PREDICTED: hypothetical protein XP_002347678 [Homo sapiens] Length = 304 Score = 40.4 bits (93), Expect = 0.003 Identities = 69/265 (26%), Positives = 88/265 (33%), Gaps = 38/265 (14%) Query: 125 GKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFR-----GSEMNSESR 179 G P G + P+G G G+AGP GRG G R Sbjct: 62 GGGPAAGSAILRAGSRSPRGA-----GPGAAGPRAAGRGGAGGGGRCCTRGRGRFPCAGS 116 Query: 180 RGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEAL-------DDLAHQAALH 232 G+ A R H + C +P+ L G EAE AL A AALH Sbjct: 117 GGRGARSRGCHSPSCCRSSSCAWHRWPQ-LRGREAEPRASPALLICIAPRPRPALPAALH 175 Query: 233 AVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHP 292 G + A +L G A RA T P R R G +G Sbjct: 176 I----GARATAGLAAKRAQPQLCSAGTAARGRRTRASPPTPP----RPRPPGLRSGDVPR 227 Query: 293 GGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARP 352 GG R P R A G + RP + + P SF T +A Sbjct: 228 GG----ARVERPTGRRGAGGRGGAQRIPPRPLRRLVPIHPHPSHWSFCTRLLE--GWAPA 281 Query: 353 KSHSSPLSTSRDPKSSYTHTHTHTH 377 +HS L +++T+TH HTH Sbjct: 282 VTHSERLV------AAHTYTHIHTH 300 >gi|239745455 PREDICTED: hypothetical protein XP_002343496 [Homo sapiens] Length = 304 Score = 40.4 bits (93), Expect = 0.003 Identities = 69/265 (26%), Positives = 88/265 (33%), Gaps = 38/265 (14%) Query: 125 GKEPKPGGRVTLPALHLPKGVCPHHPGKGSAGPSRRGRGQRAKGFR-----GSEMNSESR 179 G P G + P+G G G+AGP GRG G R Sbjct: 62 GGGPAAGSAILRAGSRSPRGA-----GPGAAGPRAAGRGGAGGGGRCCTRGRGRFPCAGS 116 Query: 180 RGQTAAGREKHPRAGCSGEGETGASYPEELHGHEAESLLLEAL-------DDLAHQAALH 232 G+ A R H + C +P+ L G EAE AL A AALH Sbjct: 117 GGRGARSRGCHSPSCCRSSSCAWHRWPQ-LRGREAEPRASPALLICIAPRPRPALPAALH 175 Query: 233 AVRLDGDEGALQVGHGPAGRELEGPGGGAALGEQRAGATTTPGSRRRRRGAGRSAGWPHP 292 G + A +L G A RA T P R R G +G Sbjct: 176 I----GARATAGLAAKRAQPQLCSAGTAARGRRTRASPPTPP----RPRPPGLRSGDVPR 227 Query: 293 GGPSRPTRRNAPPARPDAAGEQCPRPAGARPRQAEIETDPETGSDSFSTWTSYEFNYARP 352 GG R P R A G + RP + + P SF T +A Sbjct: 228 GG----ARVERPTGRRGAGGRGGAQRIPPRPLRRLVPIHPHPSHWSFCTRLLE--GWAPA 281 Query: 353 KSHSSPLSTSRDPKSSYTHTHTHTH 377 +HS L +++T+TH HTH Sbjct: 282 VTHSERLV------AAHTYTHIHTH 300 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.132 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,125,278 Number of Sequences: 37866 Number of extensions: 1301715 Number of successful extensions: 8087 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 103 Number of HSP's successfully gapped in prelim test: 643 Number of HSP's that attempted gapping in prelim test: 6507 Number of HSP's gapped (non-prelim): 1967 length of query: 404 length of database: 18,247,518 effective HSP length: 105 effective length of query: 299 effective length of database: 14,271,588 effective search space: 4267204812 effective search space used: 4267204812 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.