BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] (2924 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 6163 0.0 gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 6163 0.0 gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 6160 0.0 gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 6007 0.0 gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 6007 0.0 gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 6003 0.0 gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 1160 0.0 gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 1160 0.0 gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 1160 0.0 gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 654 0.0 gi|116284392 mucin 2 precursor [Homo sapiens] 615 e-175 gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 612 e-174 gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 574 e-163 gi|161019170 mucin 5AC [Homo sapiens] 570 e-162 gi|134031945 SCO-spondin [Homo sapiens] 546 e-155 gi|151301154 mucin 6, gastric [Homo sapiens] 512 e-144 gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 476 e-133 gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 476 e-133 gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 430 e-119 gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 310 2e-83 gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 308 4e-83 gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 297 9e-80 gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 280 1e-74 gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 268 4e-71 gi|134268640 tectorin alpha precursor [Homo sapiens] 237 1e-61 gi|16554449 zonadhesin isoform 3 [Homo sapiens] 230 2e-59 gi|27881494 zonadhesin isoform 6 [Homo sapiens] 230 2e-59 gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 160 1e-38 gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 147 2e-34 gi|37693519 BMP-binding endothelial regulator precursor protein ... 145 4e-34 >gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] Length = 2924 Score = 6163 bits (15990), Expect = 0.0 Identities = 2924/2924 (100%), Positives = 2924/2924 (100%) Query: 1 MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMRNGPAQTR 60 MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMRNGPAQTR Sbjct: 1 MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMRNGPAQTR 60 Query: 61 VSSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECV 120 VSSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECV Sbjct: 61 VSSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECV 120 Query: 121 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR Sbjct: 121 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180 Query: 181 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGS 240 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGS Sbjct: 181 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGS 240 Query: 241 ARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSG 300 ARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSG Sbjct: 241 ARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSG 300 Query: 301 KLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC 360 KLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC Sbjct: 301 KLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC 360 Query: 361 HAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK 420 HAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK Sbjct: 361 HAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK 420 Query: 421 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT 480 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT Sbjct: 421 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT 480 Query: 481 LYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILA 540 LYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILA Sbjct: 481 LYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILA 540 Query: 541 KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPP 600 KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPP Sbjct: 541 KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPP 600 Query: 601 YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQD 660 YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQD Sbjct: 601 YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQD 660 Query: 661 DFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMF 720 DFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMF Sbjct: 661 DFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMF 720 Query: 721 APCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCE 780 APCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCE Sbjct: 721 APCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCE 780 Query: 781 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 840 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR Sbjct: 781 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 840 Query: 841 NQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLE 900 NQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLE Sbjct: 841 NQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLE 900 Query: 901 LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQV 960 LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQV Sbjct: 901 LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQV 960 Query: 961 MSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSF 1020 MSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSF Sbjct: 961 MSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSF 1020 Query: 1021 SVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTL 1080 SVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTL Sbjct: 1021 SVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTL 1080 Query: 1081 VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFG 1140 VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFG Sbjct: 1081 VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFG 1140 Query: 1141 SSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200 SSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT Sbjct: 1141 SSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200 Query: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLA 1260 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLA Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLA 1260 Query: 1261 AGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFL 1320 AGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFL Sbjct: 1261 AGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFL 1320 Query: 1321 HVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRL 1380 HVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRL Sbjct: 1321 HVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRL 1380 Query: 1381 YEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSC 1440 YEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSC Sbjct: 1381 YEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSC 1440 Query: 1441 VPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQES 1500 VPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQES Sbjct: 1441 VPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQES 1500 Query: 1501 PRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESP 1560 PRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESP Sbjct: 1501 PRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESP 1560 Query: 1561 ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPP 1620 ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPP Sbjct: 1561 ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPP 1620 Query: 1621 APRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT 1680 APRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT Sbjct: 1621 APRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT 1680 Query: 1681 PAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAG 1740 PAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAG Sbjct: 1681 PAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAG 1740 Query: 1741 HSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMS 1800 HSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMS Sbjct: 1741 HSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMS 1800 Query: 1801 LESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVL 1860 LESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVL Sbjct: 1801 LESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVL 1860 Query: 1861 PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGK 1920 PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGK Sbjct: 1861 PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGK 1920 Query: 1921 VAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRV 1980 VAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRV Sbjct: 1921 VAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRV 1980 Query: 1981 SARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALA 2040 SARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALA Sbjct: 1981 SARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALA 2040 Query: 2041 TTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDR 2100 TTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDR Sbjct: 2041 TTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDR 2100 Query: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHL 2160 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHL Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHL 2160 Query: 2161 NWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSD 2220 NWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSD Sbjct: 2161 NWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSD 2220 Query: 2221 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2280 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW Sbjct: 2221 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2280 Query: 2281 QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ 2340 QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ Sbjct: 2281 QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ 2340 Query: 2341 QPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD 2400 QPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD Sbjct: 2341 QPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD 2400 Query: 2401 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ 2460 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ Sbjct: 2401 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ 2460 Query: 2461 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRP 2520 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRP Sbjct: 2461 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRP 2520 Query: 2521 GHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDC 2580 GHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDC Sbjct: 2521 GHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDC 2580 Query: 2581 PDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYK 2640 PDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYK Sbjct: 2581 PDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYK 2640 Query: 2641 SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQT 2700 SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQT Sbjct: 2641 SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQT 2700 Query: 2701 VVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRN 2760 VVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRN Sbjct: 2701 VVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRN 2760 Query: 2761 VSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGS 2820 VSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGS Sbjct: 2761 VSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGS 2820 Query: 2821 VVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINT 2880 VVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINT Sbjct: 2821 VVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINT 2880 Query: 2881 YARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924 YARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS Sbjct: 2881 YARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924 >gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] Length = 2924 Score = 6163 bits (15990), Expect = 0.0 Identities = 2924/2924 (100%), Positives = 2924/2924 (100%) Query: 1 MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMRNGPAQTR 60 MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMRNGPAQTR Sbjct: 1 MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMRNGPAQTR 60 Query: 61 VSSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECV 120 VSSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECV Sbjct: 61 VSSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECV 120 Query: 121 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR Sbjct: 121 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180 Query: 181 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGS 240 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGS Sbjct: 181 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGS 240 Query: 241 ARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSG 300 ARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSG Sbjct: 241 ARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSG 300 Query: 301 KLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC 360 KLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC Sbjct: 301 KLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC 360 Query: 361 HAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK 420 HAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK Sbjct: 361 HAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK 420 Query: 421 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT 480 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT Sbjct: 421 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT 480 Query: 481 LYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILA 540 LYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILA Sbjct: 481 LYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILA 540 Query: 541 KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPP 600 KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPP Sbjct: 541 KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPP 600 Query: 601 YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQD 660 YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQD Sbjct: 601 YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQD 660 Query: 661 DFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMF 720 DFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMF Sbjct: 661 DFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMF 720 Query: 721 APCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCE 780 APCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCE Sbjct: 721 APCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCE 780 Query: 781 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 840 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR Sbjct: 781 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 840 Query: 841 NQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLE 900 NQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLE Sbjct: 841 NQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLE 900 Query: 901 LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQV 960 LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQV Sbjct: 901 LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQV 960 Query: 961 MSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSF 1020 MSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSF Sbjct: 961 MSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSF 1020 Query: 1021 SVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTL 1080 SVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTL Sbjct: 1021 SVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTL 1080 Query: 1081 VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFG 1140 VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFG Sbjct: 1081 VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFG 1140 Query: 1141 SSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200 SSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT Sbjct: 1141 SSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200 Query: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLA 1260 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLA Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLA 1260 Query: 1261 AGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFL 1320 AGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFL Sbjct: 1261 AGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFL 1320 Query: 1321 HVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRL 1380 HVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRL Sbjct: 1321 HVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRL 1380 Query: 1381 YEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSC 1440 YEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSC Sbjct: 1381 YEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSC 1440 Query: 1441 VPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQES 1500 VPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQES Sbjct: 1441 VPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQES 1500 Query: 1501 PRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESP 1560 PRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESP Sbjct: 1501 PRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESP 1560 Query: 1561 ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPP 1620 ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPP Sbjct: 1561 ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPP 1620 Query: 1621 APRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT 1680 APRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT Sbjct: 1621 APRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT 1680 Query: 1681 PAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAG 1740 PAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAG Sbjct: 1681 PAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAG 1740 Query: 1741 HSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMS 1800 HSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMS Sbjct: 1741 HSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMS 1800 Query: 1801 LESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVL 1860 LESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVL Sbjct: 1801 LESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVL 1860 Query: 1861 PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGK 1920 PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGK Sbjct: 1861 PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGK 1920 Query: 1921 VAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRV 1980 VAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRV Sbjct: 1921 VAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRV 1980 Query: 1981 SARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALA 2040 SARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALA Sbjct: 1981 SARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALA 2040 Query: 2041 TTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDR 2100 TTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDR Sbjct: 2041 TTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDR 2100 Query: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHL 2160 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHL Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHL 2160 Query: 2161 NWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSD 2220 NWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSD Sbjct: 2161 NWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSD 2220 Query: 2221 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2280 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW Sbjct: 2221 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2280 Query: 2281 QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ 2340 QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ Sbjct: 2281 QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ 2340 Query: 2341 QPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD 2400 QPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD Sbjct: 2341 QPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD 2400 Query: 2401 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ 2460 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ Sbjct: 2401 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ 2460 Query: 2461 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRP 2520 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRP Sbjct: 2461 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRP 2520 Query: 2521 GHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDC 2580 GHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDC Sbjct: 2521 GHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDC 2580 Query: 2581 PDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYK 2640 PDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYK Sbjct: 2581 PDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYK 2640 Query: 2641 SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQT 2700 SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQT Sbjct: 2641 SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQT 2700 Query: 2701 VVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRN 2760 VVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRN Sbjct: 2701 VVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRN 2760 Query: 2761 VSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGS 2820 VSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGS Sbjct: 2761 VSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGS 2820 Query: 2821 VVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINT 2880 VVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINT Sbjct: 2821 VVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINT 2880 Query: 2881 YARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924 YARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS Sbjct: 2881 YARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924 >gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] Length = 2924 Score = 6160 bits (15980), Expect = 0.0 Identities = 2923/2924 (99%), Positives = 2923/2924 (99%) Query: 1 MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMRNGPAQTR 60 MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMRNGPAQTR Sbjct: 1 MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMRNGPAQTR 60 Query: 61 VSSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECV 120 VSSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECV Sbjct: 61 VSSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECV 120 Query: 121 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR Sbjct: 121 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180 Query: 181 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGS 240 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGS Sbjct: 181 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGS 240 Query: 241 ARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSG 300 ARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSG Sbjct: 241 ARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSG 300 Query: 301 KLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC 360 KLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC Sbjct: 301 KLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC 360 Query: 361 HAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK 420 HAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK Sbjct: 361 HAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK 420 Query: 421 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT 480 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT Sbjct: 421 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT 480 Query: 481 LYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILA 540 LYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILA Sbjct: 481 LYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILA 540 Query: 541 KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPP 600 KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPP Sbjct: 541 KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPP 600 Query: 601 YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQD 660 YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQD Sbjct: 601 YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQD 660 Query: 661 DFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMF 720 DFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMF Sbjct: 661 DFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMF 720 Query: 721 APCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCE 780 APCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCE Sbjct: 721 APCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCE 780 Query: 781 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 840 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR Sbjct: 781 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 840 Query: 841 NQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLE 900 NQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLE Sbjct: 841 NQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLE 900 Query: 901 LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQV 960 LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQV Sbjct: 901 LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQV 960 Query: 961 MSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSF 1020 MSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSF Sbjct: 961 MSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSF 1020 Query: 1021 SVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTL 1080 SVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTL Sbjct: 1021 SVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTL 1080 Query: 1081 VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFG 1140 VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFG Sbjct: 1081 VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFG 1140 Query: 1141 SSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200 SSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT Sbjct: 1141 SSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200 Query: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLA 1260 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLA Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLA 1260 Query: 1261 AGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFL 1320 AGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFL Sbjct: 1261 AGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFL 1320 Query: 1321 HVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRL 1380 HVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRL Sbjct: 1321 HVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRL 1380 Query: 1381 YEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSC 1440 YEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSC Sbjct: 1381 YEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSC 1440 Query: 1441 VPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQES 1500 VPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQES Sbjct: 1441 VPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQES 1500 Query: 1501 PRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESP 1560 PRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESP Sbjct: 1501 PRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESP 1560 Query: 1561 ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPP 1620 ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPP Sbjct: 1561 ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPP 1620 Query: 1621 APRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT 1680 APRFPLMTKAVTVRGHGSLPVRTTP QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT Sbjct: 1621 APRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT 1680 Query: 1681 PAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAG 1740 PAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAG Sbjct: 1681 PAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAG 1740 Query: 1741 HSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMS 1800 HSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMS Sbjct: 1741 HSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMS 1800 Query: 1801 LESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVL 1860 LESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVL Sbjct: 1801 LESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVL 1860 Query: 1861 PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGK 1920 PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGK Sbjct: 1861 PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGK 1920 Query: 1921 VAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRV 1980 VAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRV Sbjct: 1921 VAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRV 1980 Query: 1981 SARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALA 2040 SARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALA Sbjct: 1981 SARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALA 2040 Query: 2041 TTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDR 2100 TTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDR Sbjct: 2041 TTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDR 2100 Query: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHL 2160 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHL Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHL 2160 Query: 2161 NWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSD 2220 NWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSD Sbjct: 2161 NWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSD 2220 Query: 2221 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2280 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW Sbjct: 2221 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2280 Query: 2281 QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ 2340 QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ Sbjct: 2281 QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ 2340 Query: 2341 QPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD 2400 QPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD Sbjct: 2341 QPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD 2400 Query: 2401 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ 2460 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ Sbjct: 2401 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ 2460 Query: 2461 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRP 2520 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRP Sbjct: 2461 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRP 2520 Query: 2521 GHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDC 2580 GHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDC Sbjct: 2521 GHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDC 2580 Query: 2581 PDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYK 2640 PDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYK Sbjct: 2581 PDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYK 2640 Query: 2641 SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQT 2700 SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQT Sbjct: 2641 SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQT 2700 Query: 2701 VVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRN 2760 VVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRN Sbjct: 2701 VVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRN 2760 Query: 2761 VSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGS 2820 VSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGS Sbjct: 2761 VSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGS 2820 Query: 2821 VVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINT 2880 VVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINT Sbjct: 2821 VVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINT 2880 Query: 2881 YARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924 YARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS Sbjct: 2881 YARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924 >gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] Length = 2852 Score = 6007 bits (15583), Expect = 0.0 Identities = 2848/2852 (99%), Positives = 2848/2852 (99%), Gaps = 1/2852 (0%) Query: 74 MGDKATVVGGQ-AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 132 MGDKATVVGGQ AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA Sbjct: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60 Query: 133 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 192 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV Sbjct: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120 Query: 193 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 252 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV Sbjct: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180 Query: 253 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS Sbjct: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240 Query: 313 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 372 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS Sbjct: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300 Query: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360 Query: 433 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 492 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC Sbjct: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420 Query: 493 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 552 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL Sbjct: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480 Query: 553 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 612 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS Sbjct: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540 Query: 613 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600 Query: 673 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 732 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY Sbjct: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660 Query: 733 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 792 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC Sbjct: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720 Query: 793 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY Sbjct: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780 Query: 853 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 912 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL Sbjct: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840 Query: 913 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 972 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG Sbjct: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900 Query: 973 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 1032 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS Sbjct: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960 Query: 1033 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW Sbjct: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020 Query: 1093 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1152 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL Sbjct: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080 Query: 1153 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1212 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF Sbjct: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140 Query: 1213 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1272 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG Sbjct: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200 Query: 1273 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1332 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK Sbjct: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260 Query: 1333 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1392 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL Sbjct: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320 Query: 1393 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDE 1452 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPR CVPVCPTPQVLDE Sbjct: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380 Query: 1453 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1512 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP Sbjct: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440 Query: 1513 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI Sbjct: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500 Query: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT Sbjct: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560 Query: 1633 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV Sbjct: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620 Query: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1752 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ Sbjct: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680 Query: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740 Query: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1872 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800 Query: 1873 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1932 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT Sbjct: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860 Query: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1992 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV Sbjct: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920 Query: 1993 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 2052 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV Sbjct: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980 Query: 2053 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS Sbjct: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040 Query: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100 Query: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2232 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM Sbjct: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160 Query: 2233 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT Sbjct: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220 Query: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2352 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280 Query: 2353 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2412 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV Sbjct: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340 Query: 2413 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2472 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL Sbjct: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400 Query: 2473 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2532 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS Sbjct: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460 Query: 2533 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2592 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA Sbjct: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520 Query: 2593 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2652 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP Sbjct: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580 Query: 2653 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2712 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT Sbjct: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640 Query: 2713 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2772 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT Sbjct: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700 Query: 2773 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2832 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC Sbjct: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760 Query: 2833 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2892 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG Sbjct: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820 Query: 2893 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS Sbjct: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852 >gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] Length = 2852 Score = 6007 bits (15583), Expect = 0.0 Identities = 2848/2852 (99%), Positives = 2848/2852 (99%), Gaps = 1/2852 (0%) Query: 74 MGDKATVVGGQ-AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 132 MGDKATVVGGQ AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA Sbjct: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60 Query: 133 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 192 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV Sbjct: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120 Query: 193 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 252 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV Sbjct: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180 Query: 253 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS Sbjct: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240 Query: 313 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 372 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS Sbjct: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300 Query: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360 Query: 433 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 492 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC Sbjct: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420 Query: 493 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 552 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL Sbjct: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480 Query: 553 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 612 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS Sbjct: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540 Query: 613 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600 Query: 673 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 732 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY Sbjct: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660 Query: 733 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 792 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC Sbjct: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720 Query: 793 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY Sbjct: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780 Query: 853 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 912 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL Sbjct: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840 Query: 913 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 972 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG Sbjct: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900 Query: 973 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 1032 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS Sbjct: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960 Query: 1033 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW Sbjct: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020 Query: 1093 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1152 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL Sbjct: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080 Query: 1153 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1212 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF Sbjct: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140 Query: 1213 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1272 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG Sbjct: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200 Query: 1273 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1332 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK Sbjct: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260 Query: 1333 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1392 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL Sbjct: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320 Query: 1393 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDE 1452 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPR CVPVCPTPQVLDE Sbjct: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380 Query: 1453 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1512 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP Sbjct: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440 Query: 1513 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI Sbjct: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500 Query: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT Sbjct: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560 Query: 1633 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV Sbjct: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620 Query: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1752 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ Sbjct: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680 Query: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740 Query: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1872 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800 Query: 1873 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1932 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT Sbjct: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860 Query: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1992 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV Sbjct: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920 Query: 1993 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 2052 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV Sbjct: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980 Query: 2053 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS Sbjct: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040 Query: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100 Query: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2232 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM Sbjct: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160 Query: 2233 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT Sbjct: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220 Query: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2352 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280 Query: 2353 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2412 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV Sbjct: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340 Query: 2413 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2472 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL Sbjct: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400 Query: 2473 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2532 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS Sbjct: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460 Query: 2533 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2592 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA Sbjct: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520 Query: 2593 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2652 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP Sbjct: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580 Query: 2653 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2712 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT Sbjct: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640 Query: 2713 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2772 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT Sbjct: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700 Query: 2773 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2832 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC Sbjct: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760 Query: 2833 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2892 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG Sbjct: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820 Query: 2893 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS Sbjct: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852 >gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] Length = 2852 Score = 6003 bits (15573), Expect = 0.0 Identities = 2847/2852 (99%), Positives = 2847/2852 (99%), Gaps = 1/2852 (0%) Query: 74 MGDKATVVGGQ-AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 132 MGDKATVVGGQ AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA Sbjct: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60 Query: 133 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 192 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV Sbjct: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120 Query: 193 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 252 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV Sbjct: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180 Query: 253 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS Sbjct: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240 Query: 313 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 372 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS Sbjct: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300 Query: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360 Query: 433 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 492 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC Sbjct: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420 Query: 493 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 552 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL Sbjct: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480 Query: 553 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 612 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS Sbjct: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540 Query: 613 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600 Query: 673 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 732 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY Sbjct: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660 Query: 733 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 792 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC Sbjct: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720 Query: 793 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY Sbjct: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780 Query: 853 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 912 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL Sbjct: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840 Query: 913 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 972 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG Sbjct: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900 Query: 973 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 1032 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS Sbjct: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960 Query: 1033 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW Sbjct: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020 Query: 1093 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1152 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL Sbjct: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080 Query: 1153 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1212 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF Sbjct: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140 Query: 1213 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1272 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG Sbjct: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200 Query: 1273 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1332 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK Sbjct: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260 Query: 1333 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1392 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL Sbjct: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320 Query: 1393 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDE 1452 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPR CVPVCPTPQVLDE Sbjct: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380 Query: 1453 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1512 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP Sbjct: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440 Query: 1513 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI Sbjct: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500 Query: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT Sbjct: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560 Query: 1633 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692 VRGHGSLPVRTTP QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV Sbjct: 1561 VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620 Query: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1752 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ Sbjct: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680 Query: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740 Query: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1872 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800 Query: 1873 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1932 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT Sbjct: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860 Query: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1992 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV Sbjct: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920 Query: 1993 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 2052 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV Sbjct: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980 Query: 2053 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS Sbjct: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040 Query: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100 Query: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2232 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM Sbjct: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160 Query: 2233 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT Sbjct: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220 Query: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2352 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280 Query: 2353 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2412 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV Sbjct: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340 Query: 2413 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2472 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL Sbjct: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400 Query: 2473 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2532 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS Sbjct: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460 Query: 2533 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2592 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA Sbjct: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520 Query: 2593 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2652 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP Sbjct: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580 Query: 2653 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2712 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT Sbjct: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640 Query: 2713 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2772 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT Sbjct: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700 Query: 2773 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2832 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC Sbjct: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760 Query: 2833 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2892 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG Sbjct: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820 Query: 2893 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS Sbjct: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852 >gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo sapiens] Length = 2250 Score = 1160 bits (3001), Expect = 0.0 Identities = 545/1385 (39%), Positives = 800/1385 (57%), Gaps = 72/1385 (5%) Query: 111 FSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLS 170 + C NG C CDC+ F A G RCQ++ N G RD IC+ WGQ+H ETFDG+YYY Sbjct: 24 YECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFP 83 Query: 171 GKGSYTLV---GRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-AKEVT 226 G SY G EP +++ VHN P+C S Y+C R++SLFF ++EI + E+ Sbjct: 84 GNCSYIFAKDCGDLEPR---YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIK 140 Query: 227 HGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286 G+ + LP +G +++LA Y++V+ F+LAWDG S +Y+K+S + G + GLCGN Sbjct: 141 KNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGN 200 Query: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346 N DD + T+D+ F +SW Q P+ T S PC P + ++ Sbjct: 201 YNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPA-FEAIF 259 Query: 347 EQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQ 406 +C+ LL+ PF +CH Y+ P + ASC +DLC++ D T+CRA EYARAC+ AG P+Q Sbjct: 260 FKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYPIQ 318 Query: 407 GWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGG 466 WR CT C + +F + +CI+CCP +C C+ S + C+DGCYCP+GL+ ++G Sbjct: 319 DWRDDFPACTDKCDD-SFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGT 377 Query: 467 CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 526 C++ CPC FHG Y GS ++++C C C G W C+ CP +CSV GD HFTTFDG Sbjct: 378 CISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDG 437 Query: 527 RRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 586 R Y+F CQYIL K FT+TLQ APC N C+QS+++IL D +QVTL + Sbjct: 438 RHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRG 497 Query: 587 GDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVED 646 G +L + EI+ LSS+F+ ++T G+++L+ +G R+Y+Q+ W Sbjct: 498 GQILTSPNQGF---NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRR 554 Query: 647 TVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAAS 706 T+GLCGTFNGN +DDFLSP G+ E TPQL N+W+ S C V +DPC+++ Q Sbjct: 555 TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIG 614 Query: 707 YSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPV 766 Y+ C V+ E+FAPC ++SP Y++ CR DAC+CG CLC LAHYA+LC +HG+P+ Sbjct: 615 YAAH-CDVIHQELFAPCHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPI 673 Query: 767 DFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPP 826 DFR ++ CA+ C+ Y C + C +C L+SPE C D+C EGC CP Sbjct: 674 DFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCS---------DDCAEGCNCPE 724 Query: 827 DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA---C 883 + + + CVP C CH++G Y PG+ G C C +G + CD A +A C Sbjct: 725 GKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHIC 784 Query: 884 PAGQVFVNCSDLHTDLE---LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 940 P G+ + +C +L ++ E TC +N + + PC+SGC C G Sbjct: 785 PEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPG--------- 835 Query: 941 LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLP 1000 VC+RG F CT +PC + CT YGDRHY +FDGL Sbjct: 836 ---------------------------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLE 868 Query: 1001 FDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSP 1060 +D++ C+V L+KS D SVI +N C+ + ++C K + I+VG++ I +D Sbjct: 869 YDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQ 928 Query: 1061 ESF-LDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119 F L++K W+ G++ +V+FP++ IT+LWD++TT+H++ GPQW+ +L+GLCGNFD Sbjct: 929 SGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDK 988 Query: 1120 KTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEV 1179 T N+M T NLE+ N + FG SWA +C + C + + P+AKKECSIL S++ Sbjct: 989 CTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDI 1048 Query: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCP 1239 F C V+DVT F NC DTC C+ GGDCEC C S++AYA++CCQ G+++ WR+ +C Sbjct: 1049 FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108 Query: 1240 YDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYK 1299 DC+++N+ LG+GPY L+S G ++G + + V + F++T L+K Sbjct: 1109 LDCEYYNEGLGEGPYMLASYGQSGLVLGANMTSRSVFCLPRSSVHTSLFFYFMITPGLFK 1168 Query: 1300 AKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVAL 1359 K +VSLE+A+RPN+FL+V N +L L W+ F + A+F H+G G A Sbjct: 1169 EKVSSLALVSLESAERPNYFLYVHDNDTLSLELWEANSAFHRRATFFHHQGLWIPGYSAF 1228 Query: 1360 ESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPC 1419 E +K F+ + + + Y+ +E F+ + F + + + + +CEWRY+ CA+PC Sbjct: 1229 ELYSKKGFFIIFTDSSVKASKYDDSEEFKHSSSFSIEEIQAAVPYRKMCEWRYEPCATPC 1288 Query: 1420 FQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNET 1479 F+TC DP A +C+ +P C+P CP +LDEVT +CVY DC+ +PTE Sbjct: 1289 FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV---IPTEP---TL 1342 Query: 1480 LPPSQ 1484 +PP++ Sbjct: 1343 MPPAK 1347 Score = 742 bits (1916), Expect = 0.0 Identities = 360/923 (39%), Positives = 506/923 (54%), Gaps = 20/923 (2%) Query: 2013 PVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------DCVRHICLE 2066 P + P+ + P ++ E + + T + T TT + Q DC ++ICL Sbjct: 1337 PTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLN 1396 Query: 2067 GQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSH 2126 + N S +CP+ P CG G V+V D CCP WEC CRCS+ +LS +TFDG++ Sbjct: 1397 MEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNN 1456 Query: 2127 VALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNR 2186 AL+ A YIL + P E++ H+ C C LN+T H++ ++R R Sbjct: 1457 AALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR 1516 Query: 2187 KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH- 2245 KV VD V P S IED+G MY+I TP+ + I+W H +G++ + + Sbjct: 1517 KVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYT 1576 Query: 2246 -GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDC 2304 GLCGIC+ D +DL +++G+++ ED F++SW++ S + R +C DC Sbjct: 1577 EGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR--NCTEHDC 1634 Query: 2305 SPCLRMVSNRTFSACHRFVPPESFCE-LWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWR 2363 S C+ +++ R F CH V PE FCE +WI T + C AL+ YVA+C+KF +CI+WR Sbjct: 1635 SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQWR 1694 Query: 2364 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRH 2423 DYC C YQ CV CE G C L E CVC GT+LHR H Sbjct: 1695 TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS---CLNLREDCVCKVGTVLHRPH 1751 Query: 2424 SALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCL 2483 SA CIPE +CACTDS PR GE WN + C ++C +I+P++ C C Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811 Query: 2484 RFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDP 2543 R EV + + K CC VC C+ TLCE PTC +L+ SCCP Y CECDP Sbjct: 1812 REAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDP 1871 Query: 2544 DLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELC 2603 C + P CR+DQ +I R + CC S FC C C +P C +GE LTV N+T C Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931 Query: 2604 CPLYQCVCENFRCPQ--VQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQ 2661 CP Y CVCE CP + C LV+ +CCP CEC+C+ + +P C + E + Sbjct: 1932 CPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEVGEFTA 1991 Query: 2662 LDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTTVLDP 2721 +D H+ ++ CGC +Y C K VC+ +E+ V+ PGQ++++ + C+T C D Sbjct: 1992 ID----HNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYTIECLEEKDN 2047 Query: 2722 LTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASW 2781 T F+ +N T V C C+ +Q Y CCG+C+NVSC F NGT+ ++ G++W Sbjct: 2048 HTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTW 2107 Query: 2782 IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKK 2841 +C + C T GA+++ + CPP NETEC G V EGCC+ CK + R C+K Sbjct: 2108 HYNCTTYECVKTDEGAIILNYTMVCPPFNETECKMSEGIVKLYNEGCCKICKREERICQK 2167 Query: 2842 VTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLF 2901 V I+ IRK +C S +P+N+ SCDG+CPSA+IYN NI ++ RFCKCCRE G++ SV L+ Sbjct: 2168 VIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCKCCRENGVRNLSVPLY 2227 Query: 2902 CATNATWVPYTVQEPTDCACQWS 2924 C+ N T + YT+QEP DC CQW+ Sbjct: 2228 CSGNGTEIMYTLQEPIDCTCQWN 2250 Score = 85.1 bits (209), Expect = 9e-16 Identities = 123/516 (23%), Positives = 187/516 (36%), Gaps = 105/516 (20%) Query: 2076 QHCPQGAAPPRCGILGLA--------------VRVGGDRCCPLWECACRCSIFPDLSFVT 2121 ++CP CG GLA V VGG C +C +CS+ D F T Sbjct: 382 ENCP-------CGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTT 434 Query: 2122 FDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQ 2178 FDG H + YIL + + +T+ C+ NLG + CL + + Sbjct: 435 FDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQ-NLGLV-----CLQSITL------ 482 Query: 2179 VTIDRFNRKVTVDLQPVWPPVSRYGF------RIEDTGHMYMIL-TPSDIQIQWLHSSGL 2231 + D FN++VT+ GF I+ ++++L T ++I + Sbjct: 483 ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER 542 Query: 2232 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2291 + ++ + K + GLCG +G+ +D G + G P ++W+V S Sbjct: 543 IYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG---TPQLHANAWRVSS------- 592 Query: 2292 TRFRPDSCATTDCSPC------------LRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2339 T F P D PC ++ F+ CH ++ P + +L D Sbjct: 593 TCFAPVHVPVVD--PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHDACKC 650 Query: 2340 QQPCV--ALTVYVAMCHKFHVCIEWR-RSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2396 C+ AL Y +C + V I++R + +C +C Y C C + Sbjct: 651 GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHC------SSFCLHSCI 704 Query: 2397 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC--TDSMGVPRALGETWNSSL 2453 PE C EGC C EG + C+P C C S+ P L T S L Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT-PSGL 762 Query: 2454 SGCCQHQCQAPDTIVPVDLG-CPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2512 C + + P + CP + RF + LP C +T C Sbjct: 763 CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPE--LPAGGVNC--------ETTCA 812 Query: 2513 GLAP--TCRPGHRLLTHFQEDSCCPSYSCECDPDLC 2546 LA TC P S C S C C P +C Sbjct: 813 NLAMNFTCTP----------SSPCIS-GCVCAPGVC 837 Score = 79.7 bits (195), Expect = 4e-14 Identities = 107/510 (20%), Positives = 172/510 (33%), Gaps = 117/510 (22%) Query: 426 YNECIACCPASCHPRASCVDSEIACVDGC--YCPNGLIFEDGG--CVAPAEC----PCEF 477 Y C C +C + + V+GC YCP +I ++ CV P +C P E Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTE- 1339 Query: 478 HGTLYPPGSVVKE------------------------------------DCNTCTCTSGK 501 TL PP DC+ C + + Sbjct: 1340 -PTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNME 1398 Query: 502 WE-------------------------------CSTAVCPAECSVTGDIHFTTFDGRRYT 530 W+ C CP CS+ ++ TFDG Sbjct: 1399 WQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAA 1458 Query: 531 FPATCQYILAKSRSSGTFTVTLQNAPCGLNQ------DGACVQSVSVILHQDPRRQVTLT 584 + YIL + + C +NQ G C + ++V P ++ + Sbjct: 1459 LYSMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTT---PIHKIIVN 1512 Query: 585 QAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRW- 643 + + D + P++ I S+++ + T G+ + + + + R+ Sbjct: 1513 RLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSHLTGIIDIHFGFRFN 1571 Query: 644 -VEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ---LFGNSWKTLSACSPLVSGSPLDPCD 699 T GLCG N + DD G + + LF SW+ + + P+ C Sbjct: 1572 LSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWE-IEKSFEVTMRRPVRNCT 1630 Query: 700 VHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLC 759 H + Q +L +F PC +SP + E+ + C L+ Y LC Sbjct: 1631 EHDCS-----QCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWN-YECDALSAYVALC 1684 Query: 760 RRHGLPVDFRARLPACALSCEASKEYSPCVAPC-GRTC--QDLASPEACGVDGGDDLSRD 816 + + + +R C+LSC KEY PCV PC RTC Q +C Sbjct: 1685 NKFDICIQWRTP-DYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC----------L 1733 Query: 817 ECVEGCACPPDTYLD-TQADLCVPRNQCSC 845 E C C T L + C+P +C+C Sbjct: 1734 NLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763 Score = 65.1 bits (157), Expect = 1e-09 Identities = 91/363 (25%), Positives = 135/363 (37%), Gaps = 64/363 (17%) Query: 145 PERDSICRA--WGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 202 PE + CR + + TFDG L SY LV G+ I V + +C + Sbjct: 1433 PEWECPCRCSMLSELSIITFDGNNAALYSMASYILV---RIPGE---IIVAHIEKCSMNQ 1486 Query: 203 YTCSRAVSLFFVG---EQEIH------LAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVR 253 R L F IH LA++V + V LP ++ ++ Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT 1546 Query: 254 HQSAFTLAWD---GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKL---TDDVV 307 + + W G ++ L +T GLCG N DP DDL +G + +D+ Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606 Query: 308 EFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL-RPPFDACHAYVSP 366 F+ SW+ + + T P C + + QC LL R F CH VSP Sbjct: 1607 LFIESWEIEKSFE----VTMRRPVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSP 1655 Query: 367 LPFTASCTSDLCQSMGDVATW-----CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE 421 D C+ M T+ C AL+ Y C + +Q WRT C++ C E Sbjct: 1656 --------EDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQ-WRTP-DYCSLSCPE 1705 Query: 422 KAFTYNECIACCPA-SC-----HPRASCVDSEIACVDGCYCPNGLIF---EDGGCVAPAE 472 Y C+ C A +C + SC++ + C C G + C+ E Sbjct: 1706 -GKEYQPCVRPCEARTCLNQWFYGHTSCLNLR----EDCVCKVGTVLHRPHSAQCIPEKE 1760 Query: 473 CPC 475 C C Sbjct: 1761 CAC 1763 Score = 62.8 bits (151), Expect = 5e-09 Identities = 83/394 (21%), Positives = 137/394 (34%), Gaps = 62/394 (15%) Query: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLS--------------FVTFDG 2124 P G+ P C + G C RC I P++ F TFDG Sbjct: 18 PSGSCPYECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDG 77 Query: 2125 SHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNW---PPFCLVMLNMTH------L 2175 + YI ++ DC + W P CL + + Sbjct: 78 IYYYFPGNCSYIFAK-----------DCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFF 126 Query: 2176 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2235 ++Q I + ++ + + P + IE ++ T + W SG+ + + Sbjct: 127 SNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYL-K 185 Query: 2236 ASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW--QVPSSLTSVGQTR 2293 S+ K + GLCG + ++D + ED A F +SW Q P V Sbjct: 186 LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYT---EDIAMFANSWSVQTPDDTKCVLTPS 242 Query: 2294 FRPDSCATTDCSPCLRMVSNRT-------FSACHRFVPPESFCELWIRD---TKYVQQPC 2343 P+ C++ P + + F +CH ++ P + + D T + C Sbjct: 243 DFPNPCSSG--MPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYC 300 Query: 2344 VALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDGILGPLDP 2401 A T Y C I+ R D+ C C ++ C++ C P T + LG Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG--SN 358 Query: 2402 EHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435 HC +GC C +G ++ + CI C C Sbjct: 359 LHCL---DGCYCPDGLVM---DNGTCISLENCPC 386 Score = 44.3 bits (103), Expect = 0.002 Identities = 58/283 (20%), Positives = 104/283 (36%), Gaps = 27/283 (9%) Query: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLN 2161 C + C C+I+ D + +FDG + L +S D+ + K + Sbjct: 844 CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903 Query: 2162 WPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS-D 2220 L+ + T + T + +K Q + ++ +++ G+ ++ P D Sbjct: 904 CSKSVLISVGDTEIYLNDT--PYKQK-----QSGFFLENKSTYQLWKAGYYIVVYFPEKD 956 Query: 2221 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2280 I I W + + I + K + GLCG D +ND+T + V A F DSW Sbjct: 957 ITILWDRKTTIHI-KVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR---VFGDSW 1012 Query: 2281 -----QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD 2335 + P + A +CS ++ + F++C + SF + D Sbjct: 1013 ALGQCESPDETIKPCEAHQNKFPYAKKECS----ILYSDIFASCRNVIDVTSFAKNCHED 1068 Query: 2336 T------KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLC 2372 T + C ++ Y C + + I WR S C C Sbjct: 1069 TCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111 Score = 43.1 bits (100), Expect = 0.004 Identities = 100/480 (20%), Positives = 164/480 (34%), Gaps = 79/480 (16%) Query: 785 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 842 Y PC PC +TC D PEA VEGC CP + LD CV Sbjct: 1281 YEPCATPCFKTCSD---PEALACKFLPP------VEGCLPYCPKNMILDEVTLKCVYPRD 1331 Query: 843 CS--CHFQGVDYPPGDSDIP--SLGHCHCKDGVMSCDSRAPAAACPAG-QVFVNCSDLHT 897 C + PP +P ++ + D P Q F D Sbjct: 1332 CIPVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQ 1391 Query: 898 DLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG 957 + L+ E QL N S++ CP+ + E C ++G+ Sbjct: 1392 YICLNME----WQLYNWSLN----------CPKDV----------EMPDCGFRGRPVQVN 1427 Query: 958 DQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 1017 + P C C+ C+ + TFDG LV+ + Sbjct: 1428 SDICCPEWECPCR--------------CSMLSELSIITFDGNNAALYSMASYILVRIPGE 1473 Query: 1018 VSFSVIVE-NVNCYSSGMI---CRKFISINVGNSLIVFDDDSGNPSPESFLD----DKQE 1069 + + I + ++N SG I C K +++ I+ + + +S + QE Sbjct: 1474 IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE 1533 Query: 1070 VHTWRVGFFTLVHFPQEHITLLWDQRT---TVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1126 + G ++ P I + W T +H GLCG + +++R Sbjct: 1534 LSIEDSGSMYVITTPAGLI-IKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLR 1592 Query: 1127 TPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECS----ILLSEVFEI 1182 +TN ++ G + E + + + + P+R + +CS +L +F Sbjct: 1593 MQNGTIITNMEDIGLFIESWEIEKSFE---VTMRRPVRN-CTEHDCSQCIDLLNRRIFIP 1648 Query: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242 CH V F C + + EC ++SAY C + + + WRTP C C Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQWRTPDYCSLSC 1703 >gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo sapiens] Length = 2250 Score = 1160 bits (3001), Expect = 0.0 Identities = 545/1385 (39%), Positives = 800/1385 (57%), Gaps = 72/1385 (5%) Query: 111 FSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLS 170 + C NG C CDC+ F A G RCQ++ N G RD IC+ WGQ+H ETFDG+YYY Sbjct: 24 YECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFP 83 Query: 171 GKGSYTLV---GRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-AKEVT 226 G SY G EP +++ VHN P+C S Y+C R++SLFF ++EI + E+ Sbjct: 84 GNCSYIFAKDCGDLEPR---YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIK 140 Query: 227 HGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286 G+ + LP +G +++LA Y++V+ F+LAWDG S +Y+K+S + G + GLCGN Sbjct: 141 KNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGN 200 Query: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346 N DD + T+D+ F +SW Q P+ T S PC P + ++ Sbjct: 201 YNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPA-FEAIF 259 Query: 347 EQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQ 406 +C+ LL+ PF +CH Y+ P + ASC +DLC++ D T+CRA EYARAC+ AG P+Q Sbjct: 260 FKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYPIQ 318 Query: 407 GWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGG 466 WR CT C + +F + +CI+CCP +C C+ S + C+DGCYCP+GL+ ++G Sbjct: 319 DWRDDFPACTDKCDD-SFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGT 377 Query: 467 CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 526 C++ CPC FHG Y GS ++++C C C G W C+ CP +CSV GD HFTTFDG Sbjct: 378 CISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDG 437 Query: 527 RRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 586 R Y+F CQYIL K FT+TLQ APC N C+QS+++IL D +QVTL + Sbjct: 438 RHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRG 497 Query: 587 GDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVED 646 G +L + EI+ LSS+F+ ++T G+++L+ +G R+Y+Q+ W Sbjct: 498 GQILTSPNQGF---NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRR 554 Query: 647 TVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAAS 706 T+GLCGTFNGN +DDFLSP G+ E TPQL N+W+ S C V +DPC+++ Q Sbjct: 555 TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIG 614 Query: 707 YSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPV 766 Y+ C V+ E+FAPC ++SP Y++ CR DAC+CG CLC LAHYA+LC +HG+P+ Sbjct: 615 YAAH-CDVIHQELFAPCHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPI 673 Query: 767 DFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPP 826 DFR ++ CA+ C+ Y C + C +C L+SPE C D+C EGC CP Sbjct: 674 DFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCS---------DDCAEGCNCPE 724 Query: 827 DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA---C 883 + + + CVP C CH++G Y PG+ G C C +G + CD A +A C Sbjct: 725 GKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHIC 784 Query: 884 PAGQVFVNCSDLHTDLE---LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 940 P G+ + +C +L ++ E TC +N + + PC+SGC C G Sbjct: 785 PEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPG--------- 835 Query: 941 LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLP 1000 VC+RG F CT +PC + CT YGDRHY +FDGL Sbjct: 836 ---------------------------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLE 868 Query: 1001 FDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSP 1060 +D++ C+V L+KS D SVI +N C+ + ++C K + I+VG++ I +D Sbjct: 869 YDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQ 928 Query: 1061 ESF-LDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119 F L++K W+ G++ +V+FP++ IT+LWD++TT+H++ GPQW+ +L+GLCGNFD Sbjct: 929 SGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDK 988 Query: 1120 KTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEV 1179 T N+M T NLE+ N + FG SWA +C + C + + P+AKKECSIL S++ Sbjct: 989 CTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDI 1048 Query: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCP 1239 F C V+DVT F NC DTC C+ GGDCEC C S++AYA++CCQ G+++ WR+ +C Sbjct: 1049 FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108 Query: 1240 YDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYK 1299 DC+++N+ LG+GPY L+S G ++G + + V + F++T L+K Sbjct: 1109 LDCEYYNEGLGEGPYMLASYGQSGLVLGANMTSRSVFCLPRSSVHTSLFFYFMITPGLFK 1168 Query: 1300 AKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVAL 1359 K +VSLE+A+RPN+FL+V N +L L W+ F + A+F H+G G A Sbjct: 1169 EKVSSLALVSLESAERPNYFLYVHDNDTLSLELWEANSAFHRRATFFHHQGLWIPGYSAF 1228 Query: 1360 ESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPC 1419 E +K F+ + + + Y+ +E F+ + F + + + + +CEWRY+ CA+PC Sbjct: 1229 ELYSKKGFFIIFTDSSVKASKYDDSEEFKHSSSFSIEEIQAAVPYRKMCEWRYEPCATPC 1288 Query: 1420 FQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNET 1479 F+TC DP A +C+ +P C+P CP +LDEVT +CVY DC+ +PTE Sbjct: 1289 FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV---IPTEP---TL 1342 Query: 1480 LPPSQ 1484 +PP++ Sbjct: 1343 MPPAK 1347 Score = 742 bits (1916), Expect = 0.0 Identities = 361/923 (39%), Positives = 506/923 (54%), Gaps = 20/923 (2%) Query: 2013 PVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------DCVRHICLE 2066 P + P+ + P ++ E + + T + T TT + Q DC ++ICL Sbjct: 1337 PTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLN 1396 Query: 2067 GQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSH 2126 + N S +CP+ P CG G V+V D CCP WEC CRCS+ +LS +TFDG++ Sbjct: 1397 MEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNN 1456 Query: 2127 VALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNR 2186 AL+ A YIL + P E++ H+ C C LN+T H++ ++R R Sbjct: 1457 AALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR 1516 Query: 2187 KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH- 2245 KV VD V P S IED+G MY+I TP+ + I+W H +G++ + + Sbjct: 1517 KVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYT 1576 Query: 2246 -GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDC 2304 GLCGIC+ D +DL +++G+++ ED F++SW++ S + R +C DC Sbjct: 1577 EGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR--NCTEHDC 1634 Query: 2305 SPCLRMVSNRTFSACHRFVPPESFCE-LWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWR 2363 S C+ +++ R F CH V PE FCE +WI T + C AL+ YVA+C+KF +CI+WR Sbjct: 1635 SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQWR 1694 Query: 2364 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRH 2423 DYC C YQ CV CE G C L E CVC GTILHR H Sbjct: 1695 TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS---CLNLREDCVCKVGTILHRPH 1751 Query: 2424 SALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCL 2483 SA CIPE +CACTDS PR GE WN + C ++C +I+P++ C C Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811 Query: 2484 RFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDP 2543 R EV + + K CC VC C+ TLCE PTC +L+ SCCP Y CECDP Sbjct: 1812 REAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDP 1871 Query: 2544 DLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELC 2603 C + P CR+DQ +I R + CC S FC C C +P C +GE LTV N+T C Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931 Query: 2604 CPLYQCVCENFRCPQ--VQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQ 2661 CP Y CVCE CP + C LV+ +CCP CEC+C+ + +P C + E + Sbjct: 1932 CPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEVGEFTA 1991 Query: 2662 LDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTTVLDP 2721 +D H+ ++ CGC +Y C K VC+ +E+ V+ PGQ++++ + C+T C D Sbjct: 1992 ID----HNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYTIECLEEKDN 2047 Query: 2722 LTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASW 2781 T F+ +N T V C C+ +Q Y CCG+C+NVSC F NGT+ ++ G++W Sbjct: 2048 HTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTW 2107 Query: 2782 IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKK 2841 +C + C T GA+++ + CPP NETEC G V EGCC+ CK + R C+K Sbjct: 2108 HYNCTTYECVKTDEGAIILNYTMVCPPFNETECKMNEGIVKLYNEGCCKICKREERICQK 2167 Query: 2842 VTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLF 2901 V I+ IRK +C S +P+N+ SCDG+CPSA+IYN NI ++ RFCKCCRE G++ SV L+ Sbjct: 2168 VIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCKCCRENGVRNLSVPLY 2227 Query: 2902 CATNATWVPYTVQEPTDCACQWS 2924 C+ N T + YT+QEP DC CQW+ Sbjct: 2228 CSGNGTEIMYTLQEPIDCTCQWN 2250 Score = 85.1 bits (209), Expect = 9e-16 Identities = 123/516 (23%), Positives = 187/516 (36%), Gaps = 105/516 (20%) Query: 2076 QHCPQGAAPPRCGILGLA--------------VRVGGDRCCPLWECACRCSIFPDLSFVT 2121 ++CP CG GLA V VGG C +C +CS+ D F T Sbjct: 382 ENCP-------CGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTT 434 Query: 2122 FDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQ 2178 FDG H + YIL + + +T+ C+ NLG + CL + + Sbjct: 435 FDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQ-NLGLV-----CLQSITL------ 482 Query: 2179 VTIDRFNRKVTVDLQPVWPPVSRYGF------RIEDTGHMYMIL-TPSDIQIQWLHSSGL 2231 + D FN++VT+ GF I+ ++++L T ++I + Sbjct: 483 ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER 542 Query: 2232 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2291 + ++ + K + GLCG +G+ +D G + G P ++W+V S Sbjct: 543 IYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG---TPQLHANAWRVSS------- 592 Query: 2292 TRFRPDSCATTDCSPC------------LRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2339 T F P D PC ++ F+ CH ++ P + +L D Sbjct: 593 TCFAPVHVPVVD--PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHDACKC 650 Query: 2340 QQPCV--ALTVYVAMCHKFHVCIEWR-RSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2396 C+ AL Y +C + V I++R + +C +C Y C C + Sbjct: 651 GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHC------SSFCLHSCI 704 Query: 2397 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC--TDSMGVPRALGETWNSSL 2453 PE C EGC C EG + C+P C C S+ P L T S L Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT-PSGL 762 Query: 2454 SGCCQHQCQAPDTIVPVDLG-CPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2512 C + + P + CP + RF + LP C +T C Sbjct: 763 CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPE--LPAGGVNC--------ETTCA 812 Query: 2513 GLAP--TCRPGHRLLTHFQEDSCCPSYSCECDPDLC 2546 LA TC P S C S C C P +C Sbjct: 813 NLAMNFTCTP----------SSPCIS-GCVCAPGVC 837 Score = 79.7 bits (195), Expect = 4e-14 Identities = 107/510 (20%), Positives = 172/510 (33%), Gaps = 117/510 (22%) Query: 426 YNECIACCPASCHPRASCVDSEIACVDGC--YCPNGLIFEDGG--CVAPAEC----PCEF 477 Y C C +C + + V+GC YCP +I ++ CV P +C P E Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTE- 1339 Query: 478 HGTLYPPGSVVKE------------------------------------DCNTCTCTSGK 501 TL PP DC+ C + + Sbjct: 1340 -PTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNME 1398 Query: 502 WE-------------------------------CSTAVCPAECSVTGDIHFTTFDGRRYT 530 W+ C CP CS+ ++ TFDG Sbjct: 1399 WQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAA 1458 Query: 531 FPATCQYILAKSRSSGTFTVTLQNAPCGLNQ------DGACVQSVSVILHQDPRRQVTLT 584 + YIL + + C +NQ G C + ++V P ++ + Sbjct: 1459 LYSMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTT---PIHKIIVN 1512 Query: 585 QAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRW- 643 + + D + P++ I S+++ + T G+ + + + + R+ Sbjct: 1513 RLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSHLTGIIDIHFGFRFN 1571 Query: 644 -VEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ---LFGNSWKTLSACSPLVSGSPLDPCD 699 T GLCG N + DD G + + LF SW+ + + P+ C Sbjct: 1572 LSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWE-IEKSFEVTMRRPVRNCT 1630 Query: 700 VHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLC 759 H + Q +L +F PC +SP + E+ + C L+ Y LC Sbjct: 1631 EHDCS-----QCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWN-YECDALSAYVALC 1684 Query: 760 RRHGLPVDFRARLPACALSCEASKEYSPCVAPC-GRTC--QDLASPEACGVDGGDDLSRD 816 + + + +R C+LSC KEY PCV PC RTC Q +C Sbjct: 1685 NKFDICIQWRTP-DYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC----------L 1733 Query: 817 ECVEGCACPPDTYLD-TQADLCVPRNQCSC 845 E C C T L + C+P +C+C Sbjct: 1734 NLREDCVCKVGTILHRPHSAQCIPEKECAC 1763 Score = 65.5 bits (158), Expect = 8e-10 Identities = 92/363 (25%), Positives = 135/363 (37%), Gaps = 64/363 (17%) Query: 145 PERDSICRA--WGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 202 PE + CR + + TFDG L SY LV G+ I V + +C + Sbjct: 1433 PEWECPCRCSMLSELSIITFDGNNAALYSMASYILV---RIPGE---IIVAHIEKCSMNQ 1486 Query: 203 YTCSRAVSLFFVG---EQEIH------LAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVR 253 R L F IH LA++V + V LP ++ ++ Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT 1546 Query: 254 HQSAFTLAWD---GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKL---TDDVV 307 + + W G ++ L +T GLCG N DP DDL +G + +D+ Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606 Query: 308 EFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL-RPPFDACHAYVSP 366 F+ SW+ + + T P C + + QC LL R F CH VSP Sbjct: 1607 LFIESWEIEKSFE----VTMRRPVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSP 1655 Query: 367 LPFTASCTSDLCQSMGDVATW-----CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE 421 D C+ M T+ C AL+ Y C + +Q WRT C++ C E Sbjct: 1656 --------EDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQ-WRTP-DYCSLSCPE 1705 Query: 422 KAFTYNECIACCPA-SC-----HPRASCVDSEIACVDGCYCPNGLIF---EDGGCVAPAE 472 Y C+ C A +C + SC++ + C C G I C+ E Sbjct: 1706 -GKEYQPCVRPCEARTCLNQWFYGHTSCLNLR----EDCVCKVGTILHRPHSAQCIPEKE 1760 Query: 473 CPC 475 C C Sbjct: 1761 CAC 1763 Score = 62.8 bits (151), Expect = 5e-09 Identities = 83/394 (21%), Positives = 137/394 (34%), Gaps = 62/394 (15%) Query: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLS--------------FVTFDG 2124 P G+ P C + G C RC I P++ F TFDG Sbjct: 18 PSGSCPYECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDG 77 Query: 2125 SHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNW---PPFCLVMLNMTH------L 2175 + YI ++ DC + W P CL + + Sbjct: 78 IYYYFPGNCSYIFAK-----------DCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFF 126 Query: 2176 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2235 ++Q I + ++ + + P + IE ++ T + W SG+ + + Sbjct: 127 SNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYL-K 185 Query: 2236 ASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW--QVPSSLTSVGQTR 2293 S+ K + GLCG + ++D + ED A F +SW Q P V Sbjct: 186 LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYT---EDIAMFANSWSVQTPDDTKCVLTPS 242 Query: 2294 FRPDSCATTDCSPCLRMVSNRT-------FSACHRFVPPESFCELWIRD---TKYVQQPC 2343 P+ C++ P + + F +CH ++ P + + D T + C Sbjct: 243 DFPNPCSSG--MPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYC 300 Query: 2344 VALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDGILGPLDP 2401 A T Y C I+ R D+ C C ++ C++ C P T + LG Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG--SN 358 Query: 2402 EHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435 HC +GC C +G ++ + CI C C Sbjct: 359 LHCL---DGCYCPDGLVM---DNGTCISLENCPC 386 Score = 44.3 bits (103), Expect = 0.002 Identities = 58/283 (20%), Positives = 104/283 (36%), Gaps = 27/283 (9%) Query: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLN 2161 C + C C+I+ D + +FDG + L +S D+ + K + Sbjct: 844 CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903 Query: 2162 WPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS-D 2220 L+ + T + T + +K Q + ++ +++ G+ ++ P D Sbjct: 904 CSKSVLISVGDTEIYLNDT--PYKQK-----QSGFFLENKSTYQLWKAGYYIVVYFPEKD 956 Query: 2221 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2280 I I W + + I + K + GLCG D +ND+T + V A F DSW Sbjct: 957 ITILWDRKTTIHI-KVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR---VFGDSW 1012 Query: 2281 -----QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD 2335 + P + A +CS ++ + F++C + SF + D Sbjct: 1013 ALGQCESPDETIKPCEAHQNKFPYAKKECS----ILYSDIFASCRNVIDVTSFAKNCHED 1068 Query: 2336 T------KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLC 2372 T + C ++ Y C + + I WR S C C Sbjct: 1069 TCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111 Score = 43.1 bits (100), Expect = 0.004 Identities = 100/480 (20%), Positives = 164/480 (34%), Gaps = 79/480 (16%) Query: 785 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 842 Y PC PC +TC D PEA VEGC CP + LD CV Sbjct: 1281 YEPCATPCFKTCSD---PEALACKFLPP------VEGCLPYCPKNMILDEVTLKCVYPRD 1331 Query: 843 CS--CHFQGVDYPPGDSDIP--SLGHCHCKDGVMSCDSRAPAAACPAG-QVFVNCSDLHT 897 C + PP +P ++ + D P Q F D Sbjct: 1332 CIPVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQ 1391 Query: 898 DLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG 957 + L+ E QL N S++ CP+ + E C ++G+ Sbjct: 1392 YICLNME----WQLYNWSLN----------CPKDV----------EMPDCGFRGRPVQVN 1427 Query: 958 DQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 1017 + P C C+ C+ + TFDG LV+ + Sbjct: 1428 SDICCPEWECPCR--------------CSMLSELSIITFDGNNAALYSMASYILVRIPGE 1473 Query: 1018 VSFSVIVE-NVNCYSSGMI---CRKFISINVGNSLIVFDDDSGNPSPESFLD----DKQE 1069 + + I + ++N SG I C K +++ I+ + + +S + QE Sbjct: 1474 IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE 1533 Query: 1070 VHTWRVGFFTLVHFPQEHITLLWDQRT---TVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1126 + G ++ P I + W T +H GLCG + +++R Sbjct: 1534 LSIEDSGSMYVITTPAGLI-IKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLR 1592 Query: 1127 TPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECS----ILLSEVFEI 1182 +TN ++ G + E + + + + P+R + +CS +L +F Sbjct: 1593 MQNGTIITNMEDIGLFIESWEIEKSFE---VTMRRPVRN-CTEHDCSQCIDLLNRRIFIP 1648 Query: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242 CH V F C + + EC ++SAY C + + + WRTP C C Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQWRTPDYCSLSC 1703 >gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens] Length = 2250 Score = 1160 bits (3001), Expect = 0.0 Identities = 545/1385 (39%), Positives = 800/1385 (57%), Gaps = 72/1385 (5%) Query: 111 FSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLS 170 + C NG C CDC+ F A G RCQ++ N G RD IC+ WGQ+H ETFDG+YYY Sbjct: 24 YECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFP 83 Query: 171 GKGSYTLV---GRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-AKEVT 226 G SY G EP +++ VHN P+C S Y+C R++SLFF ++EI + E+ Sbjct: 84 GNCSYIFAKDCGDLEPR---YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIK 140 Query: 227 HGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286 G+ + LP +G +++LA Y++V+ F+LAWDG S +Y+K+S + G + GLCGN Sbjct: 141 KNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGN 200 Query: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346 N DD + T+D+ F +SW Q P+ T S PC P + ++ Sbjct: 201 YNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPA-FEAIF 259 Query: 347 EQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQ 406 +C+ LL+ PF +CH Y+ P + ASC +DLC++ D T+CRA EYARAC+ AG P+Q Sbjct: 260 FKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYPIQ 318 Query: 407 GWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGG 466 WR CT C + +F + +CI+CCP +C C+ S + C+DGCYCP+GL+ ++G Sbjct: 319 DWRDDFPACTDKCDD-SFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGT 377 Query: 467 CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 526 C++ CPC FHG Y GS ++++C C C G W C+ CP +CSV GD HFTTFDG Sbjct: 378 CISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDG 437 Query: 527 RRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 586 R Y+F CQYIL K FT+TLQ APC N C+QS+++IL D +QVTL + Sbjct: 438 RHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRG 497 Query: 587 GDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVED 646 G +L + EI+ LSS+F+ ++T G+++L+ +G R+Y+Q+ W Sbjct: 498 GQILTSPNQGF---NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRR 554 Query: 647 TVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAAS 706 T+GLCGTFNGN +DDFLSP G+ E TPQL N+W+ S C V +DPC+++ Q Sbjct: 555 TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIG 614 Query: 707 YSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPV 766 Y+ C V+ E+FAPC ++SP Y++ CR DAC+CG CLC LAHYA+LC +HG+P+ Sbjct: 615 YAAH-CDVIHQELFAPCHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPI 673 Query: 767 DFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPP 826 DFR ++ CA+ C+ Y C + C +C L+SPE C D+C EGC CP Sbjct: 674 DFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCS---------DDCAEGCNCPE 724 Query: 827 DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA---C 883 + + + CVP C CH++G Y PG+ G C C +G + CD A +A C Sbjct: 725 GKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHIC 784 Query: 884 PAGQVFVNCSDLHTDLE---LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 940 P G+ + +C +L ++ E TC +N + + PC+SGC C G Sbjct: 785 PEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPG--------- 835 Query: 941 LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLP 1000 VC+RG F CT +PC + CT YGDRHY +FDGL Sbjct: 836 ---------------------------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLE 868 Query: 1001 FDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSP 1060 +D++ C+V L+KS D SVI +N C+ + ++C K + I+VG++ I +D Sbjct: 869 YDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQ 928 Query: 1061 ESF-LDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119 F L++K W+ G++ +V+FP++ IT+LWD++TT+H++ GPQW+ +L+GLCGNFD Sbjct: 929 SGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDK 988 Query: 1120 KTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEV 1179 T N+M T NLE+ N + FG SWA +C + C + + P+AKKECSIL S++ Sbjct: 989 CTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDI 1048 Query: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCP 1239 F C V+DVT F NC DTC C+ GGDCEC C S++AYA++CCQ G+++ WR+ +C Sbjct: 1049 FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108 Query: 1240 YDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYK 1299 DC+++N+ LG+GPY L+S G ++G + + V + F++T L+K Sbjct: 1109 LDCEYYNEGLGEGPYMLASYGQSGLVLGANMTSRSVFCLPRSSVHTSLFFYFMITPGLFK 1168 Query: 1300 AKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVAL 1359 K +VSLE+A+RPN+FL+V N +L L W+ F + A+F H+G G A Sbjct: 1169 EKVSSLALVSLESAERPNYFLYVHDNDTLSLELWEANSAFHRRATFFHHQGLWIPGYSAF 1228 Query: 1360 ESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPC 1419 E +K F+ + + + Y+ +E F+ + F + + + + +CEWRY+ CA+PC Sbjct: 1229 ELYSKKGFFIIFTDSSVKASKYDDSEEFKHSSSFSIEEIQAAVPYRKMCEWRYEPCATPC 1288 Query: 1420 FQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNET 1479 F+TC DP A +C+ +P C+P CP +LDEVT +CVY DC+ +PTE Sbjct: 1289 FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV---IPTEP---TL 1342 Query: 1480 LPPSQ 1484 +PP++ Sbjct: 1343 MPPAK 1347 Score = 740 bits (1910), Expect = 0.0 Identities = 360/923 (39%), Positives = 505/923 (54%), Gaps = 20/923 (2%) Query: 2013 PVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------DCVRHICLE 2066 P + P+ + P ++ E + + T + T TT + Q DC ++ICL Sbjct: 1337 PTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLN 1396 Query: 2067 GQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSH 2126 + N S +CP+ P CG G V+V D CCP WEC CRCS+ +LS +TFDG++ Sbjct: 1397 MEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNN 1456 Query: 2127 VALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNR 2186 AL+ A YIL + P E++ H+ C C LN+T H++ ++R R Sbjct: 1457 AALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR 1516 Query: 2187 KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH- 2245 KV VD V P S IED+G MY+I TP+ + I+W H +G++ + + Sbjct: 1517 KVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYT 1576 Query: 2246 -GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDC 2304 GLCGIC+ D +DL +++G+++ ED F++SW++ S + R +C DC Sbjct: 1577 EGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR--NCTEHDC 1634 Query: 2305 SPCLRMVSNRTFSACHRFVPPESFCE-LWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWR 2363 S C+ +++ R F CH V PE FCE +WI T + C AL+ YVA+C+KF +CI+WR Sbjct: 1635 SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQWR 1694 Query: 2364 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRH 2423 DYC C YQ CV CE G C L E CVC GTILHR H Sbjct: 1695 TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS---CLNLREDCVCKVGTILHRPH 1751 Query: 2424 SALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCL 2483 SA CIPE +CACTDS PR GE WN + C ++C +I+P++ C C Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811 Query: 2484 RFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDP 2543 R EV + + K CC VC C+ TLCE PTC +L+ SCCP Y CECDP Sbjct: 1812 REAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDP 1871 Query: 2544 DLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELC 2603 C + P CR+DQ +I R + CC S FC C C +P C +GE LTV N+T C Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931 Query: 2604 CPLYQCVCENFRCPQ--VQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQ 2661 CP Y CVCE CP + C LV+ +CCP CEC+C+ + +P C + E + Sbjct: 1932 CPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLIMPTCEVGEFTA 1991 Query: 2662 LDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTTVLDP 2721 +D H+ ++ CGC +Y C K VC+ +E+ V+ PGQ++++ + C+ C D Sbjct: 1992 ID----HNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYAIECLEEKDN 2047 Query: 2722 LTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASW 2781 T F+ +N T V C C+ +Q Y CCG+C+NVSC F NGT+ ++ G++W Sbjct: 2048 HTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTW 2107 Query: 2782 IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKK 2841 +C + C T GA+++ + CPP NETEC G V EGCC+ CK + R C+K Sbjct: 2108 HYNCTTYECVKTDEGAIILNYTMVCPPFNETECKMNEGIVKLYNEGCCKICKREERICQK 2167 Query: 2842 VTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLF 2901 V I+ IRK +C S +P+N+ SCDG+CPSA+IYN NI ++ RFCKCCRE G++ SV L+ Sbjct: 2168 VIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCKCCRENGVRNLSVPLY 2227 Query: 2902 CATNATWVPYTVQEPTDCACQWS 2924 C+ N T + YT+QEP DC CQW+ Sbjct: 2228 CSGNGTEIMYTLQEPIDCTCQWN 2250 Score = 85.1 bits (209), Expect = 9e-16 Identities = 123/516 (23%), Positives = 187/516 (36%), Gaps = 105/516 (20%) Query: 2076 QHCPQGAAPPRCGILGLA--------------VRVGGDRCCPLWECACRCSIFPDLSFVT 2121 ++CP CG GLA V VGG C +C +CS+ D F T Sbjct: 382 ENCP-------CGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTT 434 Query: 2122 FDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQ 2178 FDG H + YIL + + +T+ C+ NLG + CL + + Sbjct: 435 FDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQ-NLGLV-----CLQSITL------ 482 Query: 2179 VTIDRFNRKVTVDLQPVWPPVSRYGF------RIEDTGHMYMIL-TPSDIQIQWLHSSGL 2231 + D FN++VT+ GF I+ ++++L T ++I + Sbjct: 483 ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER 542 Query: 2232 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2291 + ++ + K + GLCG +G+ +D G + G P ++W+V S Sbjct: 543 IYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG---TPQLHANAWRVSS------- 592 Query: 2292 TRFRPDSCATTDCSPC------------LRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2339 T F P D PC ++ F+ CH ++ P + +L D Sbjct: 593 TCFAPVHVPVVD--PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHDACKC 650 Query: 2340 QQPCV--ALTVYVAMCHKFHVCIEWR-RSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2396 C+ AL Y +C + V I++R + +C +C Y C C + Sbjct: 651 GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHC------SSFCLHSCI 704 Query: 2397 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC--TDSMGVPRALGETWNSSL 2453 PE C EGC C EG + C+P C C S+ P L T S L Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT-PSGL 762 Query: 2454 SGCCQHQCQAPDTIVPVDLG-CPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2512 C + + P + CP + RF + LP C +T C Sbjct: 763 CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPE--LPAGGVNC--------ETTCA 812 Query: 2513 GLAP--TCRPGHRLLTHFQEDSCCPSYSCECDPDLC 2546 LA TC P S C S C C P +C Sbjct: 813 NLAMNFTCTP----------SSPCIS-GCVCAPGVC 837 Score = 79.7 bits (195), Expect = 4e-14 Identities = 107/510 (20%), Positives = 172/510 (33%), Gaps = 117/510 (22%) Query: 426 YNECIACCPASCHPRASCVDSEIACVDGC--YCPNGLIFEDGG--CVAPAEC----PCEF 477 Y C C +C + + V+GC YCP +I ++ CV P +C P E Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTE- 1339 Query: 478 HGTLYPPGSVVKE------------------------------------DCNTCTCTSGK 501 TL PP DC+ C + + Sbjct: 1340 -PTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNME 1398 Query: 502 WE-------------------------------CSTAVCPAECSVTGDIHFTTFDGRRYT 530 W+ C CP CS+ ++ TFDG Sbjct: 1399 WQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAA 1458 Query: 531 FPATCQYILAKSRSSGTFTVTLQNAPCGLNQ------DGACVQSVSVILHQDPRRQVTLT 584 + YIL + + C +NQ G C + ++V P ++ + Sbjct: 1459 LYSMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTT---PIHKIIVN 1512 Query: 585 QAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRW- 643 + + D + P++ I S+++ + T G+ + + + + R+ Sbjct: 1513 RLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSHLTGIIDIHFGFRFN 1571 Query: 644 -VEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ---LFGNSWKTLSACSPLVSGSPLDPCD 699 T GLCG N + DD G + + LF SW+ + + P+ C Sbjct: 1572 LSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWE-IEKSFEVTMRRPVRNCT 1630 Query: 700 VHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLC 759 H + Q +L +F PC +SP + E+ + C L+ Y LC Sbjct: 1631 EHDCS-----QCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWN-YECDALSAYVALC 1684 Query: 760 RRHGLPVDFRARLPACALSCEASKEYSPCVAPC-GRTC--QDLASPEACGVDGGDDLSRD 816 + + + +R C+LSC KEY PCV PC RTC Q +C Sbjct: 1685 NKFDICIQWRTP-DYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC----------L 1733 Query: 817 ECVEGCACPPDTYLD-TQADLCVPRNQCSC 845 E C C T L + C+P +C+C Sbjct: 1734 NLREDCVCKVGTILHRPHSAQCIPEKECAC 1763 Score = 65.5 bits (158), Expect = 8e-10 Identities = 92/363 (25%), Positives = 135/363 (37%), Gaps = 64/363 (17%) Query: 145 PERDSICRA--WGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 202 PE + CR + + TFDG L SY LV G+ I V + +C + Sbjct: 1433 PEWECPCRCSMLSELSIITFDGNNAALYSMASYILV---RIPGE---IIVAHIEKCSMNQ 1486 Query: 203 YTCSRAVSLFFVG---EQEIH------LAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVR 253 R L F IH LA++V + V LP ++ ++ Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT 1546 Query: 254 HQSAFTLAWD---GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKL---TDDVV 307 + + W G ++ L +T GLCG N DP DDL +G + +D+ Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606 Query: 308 EFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL-RPPFDACHAYVSP 366 F+ SW+ + + T P C + + QC LL R F CH VSP Sbjct: 1607 LFIESWEIEKSFE----VTMRRPVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSP 1655 Query: 367 LPFTASCTSDLCQSMGDVATW-----CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE 421 D C+ M T+ C AL+ Y C + +Q WRT C++ C E Sbjct: 1656 --------EDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQ-WRTP-DYCSLSCPE 1705 Query: 422 KAFTYNECIACCPA-SC-----HPRASCVDSEIACVDGCYCPNGLIF---EDGGCVAPAE 472 Y C+ C A +C + SC++ + C C G I C+ E Sbjct: 1706 -GKEYQPCVRPCEARTCLNQWFYGHTSCLNLR----EDCVCKVGTILHRPHSAQCIPEKE 1760 Query: 473 CPC 475 C C Sbjct: 1761 CAC 1763 Score = 62.8 bits (151), Expect = 5e-09 Identities = 83/394 (21%), Positives = 137/394 (34%), Gaps = 62/394 (15%) Query: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLS--------------FVTFDG 2124 P G+ P C + G C RC I P++ F TFDG Sbjct: 18 PSGSCPYECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDG 77 Query: 2125 SHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNW---PPFCLVMLNMTH------L 2175 + YI ++ DC + W P CL + + Sbjct: 78 IYYYFPGNCSYIFAK-----------DCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFF 126 Query: 2176 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2235 ++Q I + ++ + + P + IE ++ T + W SG+ + + Sbjct: 127 SNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYL-K 185 Query: 2236 ASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW--QVPSSLTSVGQTR 2293 S+ K + GLCG + ++D + ED A F +SW Q P V Sbjct: 186 LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYT---EDIAMFANSWSVQTPDDTKCVLTPS 242 Query: 2294 FRPDSCATTDCSPCLRMVSNRT-------FSACHRFVPPESFCELWIRD---TKYVQQPC 2343 P+ C++ P + + F +CH ++ P + + D T + C Sbjct: 243 DFPNPCSSG--MPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYC 300 Query: 2344 VALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDGILGPLDP 2401 A T Y C I+ R D+ C C ++ C++ C P T + LG Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG--SN 358 Query: 2402 EHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435 HC +GC C +G ++ + CI C C Sbjct: 359 LHCL---DGCYCPDGLVM---DNGTCISLENCPC 386 Score = 44.3 bits (103), Expect = 0.002 Identities = 58/283 (20%), Positives = 104/283 (36%), Gaps = 27/283 (9%) Query: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLN 2161 C + C C+I+ D + +FDG + L +S D+ + K + Sbjct: 844 CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903 Query: 2162 WPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS-D 2220 L+ + T + T + +K Q + ++ +++ G+ ++ P D Sbjct: 904 CSKSVLISVGDTEIYLNDT--PYKQK-----QSGFFLENKSTYQLWKAGYYIVVYFPEKD 956 Query: 2221 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2280 I I W + + I + K + GLCG D +ND+T + V A F DSW Sbjct: 957 ITILWDRKTTIHI-KVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR---VFGDSW 1012 Query: 2281 -----QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD 2335 + P + A +CS ++ + F++C + SF + D Sbjct: 1013 ALGQCESPDETIKPCEAHQNKFPYAKKECS----ILYSDIFASCRNVIDVTSFAKNCHED 1068 Query: 2336 T------KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLC 2372 T + C ++ Y C + + I WR S C C Sbjct: 1069 TCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111 Score = 43.1 bits (100), Expect = 0.004 Identities = 100/480 (20%), Positives = 164/480 (34%), Gaps = 79/480 (16%) Query: 785 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 842 Y PC PC +TC D PEA VEGC CP + LD CV Sbjct: 1281 YEPCATPCFKTCSD---PEALACKFLPP------VEGCLPYCPKNMILDEVTLKCVYPRD 1331 Query: 843 CS--CHFQGVDYPPGDSDIP--SLGHCHCKDGVMSCDSRAPAAACPAG-QVFVNCSDLHT 897 C + PP +P ++ + D P Q F D Sbjct: 1332 CIPVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQ 1391 Query: 898 DLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG 957 + L+ E QL N S++ CP+ + E C ++G+ Sbjct: 1392 YICLNME----WQLYNWSLN----------CPKDV----------EMPDCGFRGRPVQVN 1427 Query: 958 DQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 1017 + P C C+ C+ + TFDG LV+ + Sbjct: 1428 SDICCPEWECPCR--------------CSMLSELSIITFDGNNAALYSMASYILVRIPGE 1473 Query: 1018 VSFSVIVE-NVNCYSSGMI---CRKFISINVGNSLIVFDDDSGNPSPESFLD----DKQE 1069 + + I + ++N SG I C K +++ I+ + + +S + QE Sbjct: 1474 IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE 1533 Query: 1070 VHTWRVGFFTLVHFPQEHITLLWDQRT---TVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1126 + G ++ P I + W T +H GLCG + +++R Sbjct: 1534 LSIEDSGSMYVITTPAGLI-IKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLR 1592 Query: 1127 TPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECS----ILLSEVFEI 1182 +TN ++ G + E + + + + P+R + +CS +L +F Sbjct: 1593 MQNGTIITNMEDIGLFIESWEIEKSFE---VTMRRPVRN-CTEHDCSQCIDLLNRRIFIP 1648 Query: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242 CH V F C + + EC ++SAY C + + + WRTP C C Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQWRTPDYCSLSC 1703 >gi|89191868 von Willebrand factor preproprotein [Homo sapiens] Length = 2813 Score = 654 bits (1688), Expect = 0.0 Identities = 393/1135 (34%), Positives = 560/1135 (49%), Gaps = 80/1135 (7%) Query: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210 C +G V TFDG Y +G SY L G + S N + S Y + Sbjct: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVY-----LG 89 Query: 211 LFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQS-AFTLAWDGASA 267 FF +IHL VT G RV +P+ L+ AGY + ++ F DG+ Sbjct: 90 EFF----DIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGN 145 Query: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327 + +S T GLCGN N +DD +T G LT D +F +SW + Q + Sbjct: 146 FQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQ--WCERA 203 Query: 328 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 386 S P C + +G++EQC+ L F CH V P PF A C LC+ G + Sbjct: 204 SPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLEC 263 Query: 387 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC---HPRASC 443 C AL EYAR CAQ G L GW T C+ C Y +C++ C +C H C Sbjct: 264 ACPALLEYARTCAQEGMVLYGW-TDHSACSPVCPA-GMEYRQCVSPCARTCQSLHINEMC 321 Query: 444 VDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 503 + CVDGC CP G + ++G CV ECPC G YPPG+ + DCNTC C + +W Sbjct: 322 QER---CVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWI 378 Query: 504 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 563 CS CP EC VTG HF +FD R +TF CQY+LA+ +F++ ++ C ++D Sbjct: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDA 438 Query: 564 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 623 C +SV+V L V L V + Q +P D +R +V VR + G Sbjct: 439 VCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD---LRIQHTVTASVRLSYG 495 Query: 624 VRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 682 + D +G RL +++ + T GLCG +NGN DDFL+P G+ E + FGN+WK Sbjct: 496 EDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKL 555 Query: 683 LSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACR 742 C L DPC ++ + +S +AC+VLT F C +SP+PY CR D C Sbjct: 556 HGDCQDL-QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCS 614 Query: 743 C--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLA 800 C G+ CLC LA YA C G+ V +R C L+C + Y C PC TC+ L+ Sbjct: 615 CSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNLTCRSLS 673 Query: 801 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 860 P D+ + C+EGC CPP Y+D + D CVP+ QC C++ G + P D Sbjct: 674 YP--------DEECNEACLEGCFCPPGLYMDERGD-CVPKAQCPCYYDGEIFQPEDIFSD 724 Query: 861 SLGHCHCKDGVMSCD-SRAPAA-------------------ACPAGQVFVNCSDLHTDLE 900 C+C+DG M C S P + +C V + C + E Sbjct: 725 HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784 Query: 901 -LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 959 L +TC Q +L + G C+SGC CP G++RH + C E CPC +GKEY PG+ Sbjct: 785 GLECTKTC--QNYDLECMSMG-CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGET 841 Query: 960 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STS 1016 V C+TCVC+ + CT H C +TC+ G HY TFDGL + F G C+ LV+ ++ Sbjct: 842 VKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901 Query: 1017 DVSFSVIVENVNCYSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLDDKQEVHTWRV 1075 +F ++V N C + C+K ++I V G + +FD + P + D+ Sbjct: 902 PGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVES 958 Query: 1076 GFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL-T 1134 G + ++ + ++++WD+ ++ V +Q ++ GLCGNFD N++ T NL++ Sbjct: 959 GRYIILLLGKA-LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDL-TSSNLQVEE 1016 Query: 1135 NPQEFGSSW-AAVECPDTLD-PRD----MCVLNPLREPFAKKECSILLSEVFEICHPVVD 1188 +P +FG+SW + +C DT P D C N +++ C IL S+VF+ C+ +VD Sbjct: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVD 1076 Query: 1189 VTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1243 + C+ DTC C GDC CFC +++AYAH C QHG V WRT LCP C+ Sbjct: 1077 PEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCE 1131 Score = 240 bits (612), Expect = 2e-62 Identities = 232/952 (24%), Positives = 362/952 (38%), Gaps = 148/952 (15%) Query: 2066 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGS 2125 +GQ + + +C +G P C V+V + C W C C C+ VTFDG Sbjct: 1907 DGQTLLKSHRVNCDRGLRPS-CPNSQSPVKVE-ETCGCRWTCPCVCTGSSTRHIVTFDGQ 1964 Query: 2126 HVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFN 2185 + L Y+L Q+ ++ L V +L + + G C+ + + H A V + + Sbjct: 1965 NFKLTGSCSYVLFQNKEQDLEV-ILHNGACSPGARQG---CMKSIEVKHSALSVELHS-D 2019 Query: 2186 RKVTVDLQPVWPP-------VSRYG-----FRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2233 +VTV+ + V P V+ YG R GH++ TP + + Q + Sbjct: 2020 MEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTF-TPQNNEFQ--------L 2070 Query: 2234 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT- 2292 + KT ++ +GLCGICD + AND L+DG+V D + W V GQT Sbjct: 2071 QLSPKTFASKTYGLCGICDENGANDFMLRDGTVT---TDWKTLVQEWTVQRP----GQTC 2123 Query: 2293 -RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVA 2351 + C D S C +++ F+ CH+ + P +F + +D+ + +Q C + Y Sbjct: 2124 QPILEEQCLVPDSSHC-QVLLLPLFAECHKVLAPATFYAICQQDSCHQEQVCEVIASYAH 2182 Query: 2352 MCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2411 +C VC++WR D+C C Y C C P+ C + D EGC Sbjct: 2183 LCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC--PRHCDGNVSSCGDHP-----SEGC 2235 Query: 2412 VCSEGTILHRRHSALCIPEAKCA-CTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2470 C ++ C+PE C C GV E W C C + + Sbjct: 2236 FCPPDKVMLE---GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCT 2292 Query: 2471 DLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE-GLAPTCRPGHRLLTHFQ 2529 CP+ + +C EVA L D CC CVC+ C+ P C G + T Sbjct: 2293 TQPCPTAKAPTC-GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQP-TLTN 2350 Query: 2530 EDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQE 2589 C P+++C C + C+ PSC ++ + CC Y CAC +C +S C Sbjct: 2351 PGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECAC-NCVNSTVSCPL 2407 Query: 2590 G-------------------EALTVHRNTTELCCPLYQ-----CVCENF----------R 2615 G + + VHR+T ++ C C + + Sbjct: 2408 GYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQ 2467 Query: 2616 CPQVQC------GLGTALVEVWSPDRCCPYKSCECDCDT-----------------IPVP 2652 C Q C G L E RC P +CE + P Sbjct: 2468 CSQKPCEDSCRSGFTYVLHEGECCGRCLP-SACEVVTGSPRGDSQSSWKSVGSQWASPEN 2526 Query: 2653 RCHLWEKSQLDEE---------------------FMHSVENVCGCAKYECVKAPVCLSRE 2691 C + E ++ EE F S + C C + C+ Sbjct: 2527 PCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNG 2586 Query: 2692 LGVMQPGQTVVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDL 2751 V+ PG+TV+ VC T RC + ++ F ++ C+ C Y+ + Sbjct: 2587 T-VIGPGKTVMI----DVCTTCRCMVQVGVISGF-KLECRKTTCN-PCPLG--YKEENNT 2637 Query: 2752 AACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPIS-CPPLN 2810 CCG C +C G + C H C G ++ CPP + Sbjct: 2638 GECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFD 2697 Query: 2811 ETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMT-IRKNECRSSTPVNLVSCDGRCP 2869 E +C GG ++ CC TC+E C +T R+ ++ C+S V++ C G+C Sbjct: 2698 EHKCLAEGGKIMKIPGTCCDTCEEP--ECNDITARLQYVKVGSCKSEVEVDIHYCQGKCA 2755 Query: 2870 SASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2921 S ++Y+ +IN C CC + V L C TN + V + V +C C Sbjct: 2756 SKAMYSIDINDVQDQCSCCSPTRTEPMQVALHC-TNGSVVYHEVLNAMECKC 2806 Score = 233 bits (594), Expect = 2e-60 Identities = 150/461 (32%), Positives = 207/461 (44%), Gaps = 58/461 (12%) Query: 448 IACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 507 + CV GC CP G++ + CVA CPC G Y PG VK CNTC C KW C+ Sbjct: 802 MGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDH 861 Query: 508 VCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLNQDGA 564 VC A CS G H+ TFDG +Y FP CQY+L + + GTF + + N C + Sbjct: 862 VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVK 920 Query: 565 CVQSVSVILHQDPRRQVTLTQAGDVLLFD-QYKIIPPYTDDA-FEIRRLSSVFLRVRTNV 622 C + V++ L + G++ LFD + + P D+ FE+ S ++ + Sbjct: 921 CKKRVTI-----------LVEGGEIELFDGEVNVKRPMKDETHFEVVE-SGRYIILLLGK 968 Query: 623 GVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 682 + V++DR L + + + Q + E GLCG F+G +D S E P FGNSWK Sbjct: 969 ALSVVWDRH-LSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV 1027 Query: 683 LSACSPLVSGSPLDP----CDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 738 S C+ PLD C ++ + +C +LT ++F C+ + P PY + C Sbjct: 1028 SSQCAD-TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIY 1086 Query: 739 DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK----------E 784 D C C C C T+A YAH+C +HG V +R C SCE Sbjct: 1087 DTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT-LCPQSCEERNLRENGYECEWR 1145 Query: 785 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 842 Y+ C C TCQ P AC V +CVEGC CPP LD CV Sbjct: 1146 YNSCAPACQVTCQH-PEPLACPV---------QCVEGCHAHCPPGKILDELLQTCVDPED 1195 Query: 843 CS-CHFQGVDYPPG------DSDIPSLGHCHCKDGVMSCDS 876 C C G + G SD CHC ++C++ Sbjct: 1196 CPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA 1236 Score = 157 bits (396), Expect = 2e-37 Identities = 110/380 (28%), Positives = 157/380 (41%), Gaps = 31/380 (8%) Query: 511 AECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVS 570 A CS+ G TFDG Y+F C Y+LA +F++ G Q+G + VS Sbjct: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSI------IGDFQNG---KRVS 83 Query: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630 + ++ + L G V DQ ++ PY + + + G D Sbjct: 84 LSVYLGEFFDIHLFVNGTVTQGDQ-RVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDG 142 Query: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA---CS 687 G + + R+ T GLCG FN +DDF++ G S P F NSW S C Sbjct: 143 SG-NFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCE 201 Query: 688 PLVSGSPLDPCDVHLQAASYSV-QACSVL-TGEMFAPCSAFLSPVPYFEQCRRDACRC-- 743 + P C++ + + C +L + +FA C + P P+ C + C C Sbjct: 202 R--ASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259 Query: 744 GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE 803 G C C L YA C + G+ + AC+ C A EY CV+PC RTCQ L E Sbjct: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319 Query: 804 ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG 863 C ++ CV+GC+CP LD LCV +C C G YPPG S Sbjct: 320 MC---------QERCVDGCSCPEGQLLD--EGLCVESTECPCVHSGKRYPPGTSLSRDCN 368 Query: 864 HCHCKDGVMSCDSRAPAAAC 883 C C++ C + C Sbjct: 369 TCICRNSQWICSNEECPGEC 388 Score = 136 bits (342), Expect = 3e-31 Identities = 124/453 (27%), Positives = 180/453 (39%), Gaps = 72/453 (15%) Query: 101 HRAKCAPSYLFSCFNGGECVHPA----------FCDCRRFNATGPRCQMVYNAGPERDSI 150 H +C CF+ G+ P C R++N T C D+ Sbjct: 817 HENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC----------DAT 866 Query: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYTCSRAV 209 C G H TFDGL Y G+ Y LV + +F I V N C C + V Sbjct: 867 CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGN-KGCSHPSVKCKKRV 925 Query: 210 SLFFVGEQEIHLAKEVTHGGMRVQLP-------HVMGSARLQQLAGYVIVRHQSAFTLAW 262 ++ G + E+ G + V+ P V+ S R Y+I+ A ++ W Sbjct: 926 TILVEGGE-----IELFDGEVNVKRPMKDETHFEVVESGR------YIILLLGKALSVVW 974 Query: 263 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--EQAPNQ 320 D ++ + + GLCGN + +DL +S+ ++ +D V+F +SW+ Q + Sbjct: 975 DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT 1034 Query: 321 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDL--C 378 P SS P N V C L F C+ V P P+ C D C Sbjct: 1035 RKVPLDSS---PATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSC 1091 Query: 379 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK---------AFTYNEC 429 +S+GD A +C +A YA CAQ G+ + WRT C C+E+ + YN C Sbjct: 1092 ESIGDCACFCDTIAAYAHVCAQHGKVVT-WRT-ATLCPQSCEERNLRENGYECEWRYNSC 1149 Query: 430 IACCPASC-HPRASCVDSEIACVDGC--YCPNGLIFED--GGCVAPAECP-CEFHGTLYP 483 C +C HP + + CV+GC +CP G I ++ CV P +CP CE G + Sbjct: 1150 APACQVTCQHPEP--LACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFA 1207 Query: 484 PGSVV------KEDCNTCTCTSGKWECSTAVCP 510 G V E C C C C P Sbjct: 1208 SGKKVTLNPSDPEHCQICHCDVVNLTCEACQEP 1240 Score = 129 bits (323), Expect = 6e-29 Identities = 101/363 (27%), Positives = 151/363 (41%), Gaps = 58/363 (15%) Query: 494 TCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 553 TC C +W CP C+ + H TFDG+ + +C Y+L +++ V L Sbjct: 1939 TCGC---RW-----TCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILH 1989 Query: 554 NAPCGLNQDGACVQSV-------SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAF 606 N C C++S+ SV LH D + +T G + + PY Sbjct: 1990 NGACSPGARQGCMKSIEVKHSALSVELHSD----MEVTVNGRL-------VSVPYVGGNM 2038 Query: 607 EIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVDQR-WVEDTVGLCGTFNGNTQDDFLS 664 E+ ++ VR N +G + + LQ+ + + T GLCG + N +DF+ Sbjct: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098 Query: 665 PVGVPESTPQLFGNSWKTL---SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFA 721 G + + W C P++ L P H C VL +FA Sbjct: 2099 RDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSH----------CQVLLLPLFA 2148 Query: 722 PCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 781 C L+P ++ C++D+C Q +C +A YAHLCR +G+ VD+R CA+SC Sbjct: 2149 ECHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPP 2205 Query: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841 S Y+ C C R C S +CG D EGC CPPD + CVP Sbjct: 2206 SLVYNHCEHGCPRHCDGNVS--SCG---------DHPSEGCFCPPDKVM--LEGSCVPEE 2252 Query: 842 QCS 844 C+ Sbjct: 2253 ACT 2255 Score = 119 bits (298), Expect = 4e-26 Identities = 103/380 (27%), Positives = 149/380 (39%), Gaps = 50/380 (13%) Query: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209 +C H+ TFDG + L+G SY L E Q + +HN + C +++ Sbjct: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGACSPGARQGCMKSI 2005 Query: 210 SLFFVG-EQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFT------LAW 262 + E+H EVT G V +P+V G+ + Y + H+ F Sbjct: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNV---YGAIMHEVRFNHLGHIFTFT 2062 Query: 263 DGASAVYIKMSPELLGW-THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQP 321 + +++SP+ T+GLCG + + +D + G +T D V W Q P Q Sbjct: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQ- 2121 Query: 322 PGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM 381 T + CL + C+ LL P F CH ++P F A C D C Sbjct: 2122 ---TCQPILEEQCLVPDSS-------HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ- 2170 Query: 382 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR- 440 C +A YA C G + WRT C + C + YN C CP C Sbjct: 2171 ---EQVCEVIASYAHLCRTNGVCVD-WRTP-DFCAMSC-PPSLVYNHCEHGCPRHCDGNV 2224 Query: 441 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAEC-PC--------EFHGTLYPPGSVVKED 491 +SC D +GC+CP + +G CV C C +F P + Sbjct: 2225 SSCGDHP---SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD----HQP 2277 Query: 492 CNTCTCTSG-KWECSTAVCP 510 C CTC SG K C+T CP Sbjct: 2278 CQICTCLSGRKVNCTTQPCP 2297 Score = 91.3 bits (225), Expect = 1e-17 Identities = 82/333 (24%), Positives = 119/333 (35%), Gaps = 41/333 (12%) Query: 934 RHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG---SFQCTLHP---------- 980 R GD LP++C P Q + H C RG S + P Sbjct: 1888 RPGDVWTLPDQCHTV----TCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCR 1943 Query: 981 --CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI-CR 1037 C CT RH TFDG F G+C L ++ + VI+ N C C Sbjct: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN-KEQDLEVILHNGACSPGARQGCM 2002 Query: 1038 KFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092 K I + + D +G ++ EV+ + + HI Sbjct: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062 Query: 1093 DQRTTVHVQAGPQ-WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1151 Q +Q P+ + + GLCG D N+ + T+ + W T Sbjct: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122 Query: 1152 LDP--RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209 P + C++ C +LL +F CH V+ FY+ C D+C Q Sbjct: 2123 CQPILEEQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ---- 2172 Query: 1210 ECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242 C +++YAH C +GV VDWRTP C C Sbjct: 2173 --VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203 Score = 82.8 bits (203), Expect = 5e-15 Identities = 85/360 (23%), Positives = 139/360 (38%), Gaps = 55/360 (15%) Query: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLG 2158 C EC C + F +FD + Y+L++ + + + + C Sbjct: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR-- 436 Query: 2159 HLNWPPFCL--VMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMIL 2216 C V + + L + + + V +D Q V P+ + RI+ T + L Sbjct: 437 ----DAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRL 492 Query: 2217 T-PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAP 2275 + D+Q+ W G ++V+ S + GLCG +G+ +D G ED Sbjct: 493 SYGEDLQMDW-DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED--- 548 Query: 2276 FLDSWQVPSSLTSVGQ------------TRFRPDSCATTDCSPCLRMVSNRTFSACHRFV 2323 F ++W++ + + TRF ++CA ++++ TF ACHR V Sbjct: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACA---------VLTSPTFEACHRAV 599 Query: 2324 PPESFCELWIRDTKYV--------QQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2375 P + +R+ +Y + C AL Y A C V + WR C C Sbjct: 600 SPLPY----LRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKG 655 Query: 2376 STYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435 Y C T C TC+ L D E + EGC C G + R C+P+A+C C Sbjct: 656 QVYLQCGTPCN--LTCRS--LSYPDEECNEACLEGCFCPPGLYMDERGD--CVPKAQCPC 709 Score = 79.7 bits (195), Expect = 4e-14 Identities = 108/447 (24%), Positives = 164/447 (36%), Gaps = 67/447 (14%) Query: 2058 DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL--------GLAVRVGGDRC-------- 2101 +C+ C+ G L +H + A RC G V++G + C Sbjct: 798 ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWN 857 Query: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS--PDEMLTVHVLDCKSANLGH 2159 C C CS ++TFDG E Y+L Q T +L N G Sbjct: 858 CTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRIL---VGNKGC 914 Query: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS 2219 + P +T L I+ F+ +V V P F + ++G ++L Sbjct: 915 SH--PSVKCKKRVTILVEGGEIELFDGEVNVKR----PMKDETHFEVVESGRYIILLLGK 968 Query: 2220 DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDS 2279 + + W + +V +T + + GLCG DG NDLT + V EDP F +S Sbjct: 969 ALSVVWDRHLSISVV-LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQV---EEDPVDFGNS 1024 Query: 2280 WQVPSSLTSVGQTRF--RPDSCAT-----TDCSPCLRMVSNRTFSACHRFVPPESFCELW 2332 W+V S + P +C T R++++ F C++ V PE + ++ Sbjct: 1025 WKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVC 1084 Query: 2333 IRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSS----------DS 2376 I DT + C + Y +C + + WR + CP C + Sbjct: 1085 IYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEW 1144 Query: 2377 TYQACVTACEPPKTCQDGILGPLDPEHCQV-LGEGC--VCSEGTILHRRHSALCIPEAKC 2433 Y +C AC+ TCQ +P C V EGC C G IL C+ C Sbjct: 1145 RYNSCAPACQ--VTCQHP-----EPLACPVQCVEGCHAHCPPGKILDELLQT-CVDPEDC 1196 Query: 2434 ACTDSMGVPRALGE--TWNSSLSGCCQ 2458 + G A G+ T N S CQ Sbjct: 1197 PVCEVAGRRFASGKKVTLNPSDPEHCQ 1223 Score = 74.7 bits (182), Expect = 1e-12 Identities = 89/366 (24%), Positives = 137/366 (37%), Gaps = 38/366 (10%) Query: 2089 ILGLAVRVGGDRCCPLWE---CACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEML 2145 +L LA+ + G C RCS+F TFDGS + Y+L+ + Sbjct: 10 LLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS 69 Query: 2146 TVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRF-NRKVTVDLQPVWPPVSRYGF 2204 + D ++ L+ +L I F N VT Q V P + G Sbjct: 70 FSIIGDFQNGKRVSLS-----------VYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGL 118 Query: 2205 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDG 2264 +E Y + + + + SG V S + GLCG + A +D ++G Sbjct: 119 YLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEG 178 Query: 2265 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTD-------CSPCLRMVSNRTFS 2317 ++ DP F +SW + S + SC + C + S F+ Sbjct: 179 TLTS---DPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFA 235 Query: 2318 ACHRFVPPESF---CELWIRD-TKYVQQPCVALTVYVAMC-HKFHVCIEWRRSDYCPFLC 2372 CH V PE F CE + + ++ C AL Y C + V W C +C Sbjct: 236 RCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC 295 Query: 2373 SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAK 2432 + Y+ CV+ C +TCQ + + E C +GC C EG +L LC+ + Sbjct: 296 PAGMEYRQCVSPC--ARTCQSLHINEMCQERCV---DGCSCPEGQLL---DEGLCVESTE 347 Query: 2433 CACTDS 2438 C C S Sbjct: 348 CPCVHS 353 Score = 55.5 bits (132), Expect = 8e-07 Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 1/56 (1%) Query: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDC 1463 CEWRY++CA C TC+ P +C V C CP ++LDE+ Q CV EDC Sbjct: 1142 CEWRYNSCAPACQVTCQHPEPLAC-PVQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196 Score = 45.4 bits (106), Expect = 8e-04 Identities = 53/200 (26%), Positives = 73/200 (36%), Gaps = 50/200 (25%) Query: 403 RPLQGWRTQLRQC----TVHCKEKAFTYNECIACCPASCHP-------RASCVDSEIACV 451 R LQ T +C T C+++ EC P SC P + C D E C Sbjct: 2342 RGLQPTLTNPGECRPNFTCACRKE-----ECKRVSPPSCPPHRLPTLRKTQCCD-EYECA 2395 Query: 452 DGCY-----CPNGLIFE----DGGCVAPAECP---CEFHGTLYPPGSVVKEDCNTCTCTS 499 C CP G + D GC P C T+YP G +E C+ CTCT Sbjct: 2396 CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTD 2455 Query: 500 GK--------WECSTAVCPAEC--SVTGDIHFTTFDGRRYTFPATCQYILAKSR------ 543 + +CS C C T +H GR P+ C+ + R Sbjct: 2456 MEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGR--CLPSACEVVTGSPRGDSQSS 2513 Query: 544 --SSGTFTVTLQNAPCGLNQ 561 S G+ + +N PC +N+ Sbjct: 2514 WKSVGSQWASPEN-PCLINE 2532 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 615 bits (1585), Expect = e-175 Identities = 362/1124 (32%), Positives = 557/1124 (49%), Gaps = 59/1124 (5%) Query: 149 SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 208 ++C WG H +TFDG + G Y + F++ + P +P Sbjct: 35 NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94 Query: 209 VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 267 L + + I+L + + G V PH +++ Y V ++ TL W+ A Sbjct: 95 --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152 Query: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327 + +++ + T GLCG+ N S G L + EF + Q NQP Sbjct: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203 Query: 328 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 386 + P + P + +CE LL F C V P+ +C D C+ G Sbjct: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263 Query: 387 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDS 446 C +AE++R C+ AG WRT C C C H S + Sbjct: 264 VCSTVAEFSRQCSHAGGRPGNWRTATL-CPKTCPGNLVYLESGSPCMDTCSHLEVSSLCE 322 Query: 447 EIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 503 E +DGC+CP G +++D GCV ++C C HG LY PG + DC C C +G+W Sbjct: 323 EHR-MDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWV 381 Query: 504 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 563 C CP C++ G H TTFDG+ YTF C Y+LAK + ++ + + APCG Sbjct: 382 CKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQ 441 Query: 564 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 623 C+++V +L D ++ V + ++ +L ++ ++ P+ +F + R SS + V +G Sbjct: 442 TCLKTV--VLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIG 499 Query: 624 VRVLYDREG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 682 VR+ ++L++ +DQ GLCG FNG DDF + G+ E+T F N+WK Sbjct: 500 VRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA 559 Query: 683 LSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDA 740 S+C + DPC +++++A+Y+ CS+L T F C + + P Y+++C+ D Sbjct: 560 QSSCHDKLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDT 618 Query: 741 CRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRT 795 C C + CLCA L+ YA C G+ + + R C SC S+ + + C +T Sbjct: 619 CNCQNNEDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQT 677 Query: 796 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 855 C+ L+ ++ ++G V+GC CP T+LD + CVP +CSC+ +G+ G Sbjct: 678 CRSLSEADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAG 730 Query: 856 DSDIPSLGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNL 914 D + C C+DG + C R +C A ++ ++CS+L T L S+ R Q L Sbjct: 731 DVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAA 789 Query: 915 SVSARGPCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGS 973 C+SGC CP GL+ G C + +ECPC Y G ++ C+TC C+RG Sbjct: 790 GYY-HTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGR 848 Query: 974 FQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVN 1028 + CT C TC+ YG HY TFDG +DF G C V+ ++S SFS+I ENV Sbjct: 849 WVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVP 908 Query: 1029 CYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHF 1083 C ++G+ C K I I +G + + +D + + E H T VG + +V Sbjct: 909 CGTTGVTCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE- 961 Query: 1084 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1143 I ++WD+RTTV ++ P ++G + GLCGNFD ++ N+ T +++ +++ +FG+SW Sbjct: 962 SSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW 1021 Query: 1144 A-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCG 1202 A CPD + C LNP R +A+K+CSIL S VF ICH VD FY C+ D+C Sbjct: 1022 KEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCS 1081 Query: 1203 CSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246 C GGDCECFC++V++YA +C + G V WRTP LCP CD++N Sbjct: 1082 CDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1125 Score = 250 bits (639), Expect = 1e-65 Identities = 228/921 (24%), Positives = 364/921 (39%), Gaps = 187/921 (20%) Query: 97 ERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFN--------ATGPRCQMVYNAGP--- 145 E R+ C ++ CV + C CR T Q V NAG Sbjct: 323 EHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWVC 382 Query: 146 ---ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV-GRHEPEGQSFSIQVHNDPQCGSS 201 C G H+ TFDG Y G Y L G H S+++ P CGS+ Sbjct: 383 KDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHN---DSYALLGELAP-CGST 438 Query: 202 P-YTCSRAVSLFFVGEQEIHLAKE---VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSA 257 TC + V L ++ + + K V ++V LPHV S + + + Y I+ + Sbjct: 439 DKQTCLKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAI 498 Query: 258 ---FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314 + +++ + G GLCGN N DD T+SG + F ++W+ Sbjct: 499 GVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWK 558 Query: 315 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRP--PFDACHAYVSPLPF--- 369 Q+ PC N + C L + PF CH+ V P + Sbjct: 559 AQSSCHDKLDWLDD----PC-SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKR 613 Query: 370 ----TASCTSD---LCQSMGD---------VATW-------------------------- 387 T +C ++ LC ++ V W Sbjct: 614 CKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTT 673 Query: 388 ----CRALAEYARACAQAGRPLQGW----------------------------------- 408 CR+L+E C + P+ G Sbjct: 674 CQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVV 733 Query: 409 -----RTQLRQCTVHCKEKAFTYNECIA----------CCPASCHPRASCVDSEIA---- 449 R R +HC++ C A A+ PRA + A Sbjct: 734 VRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYH 793 Query: 450 --CVDGCYCPNGLIFED-GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECST 506 CV GC CP+GL+ + GGCV ECPC + LY G+ +K DCNTCTC G+W C+ Sbjct: 794 TECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQ 853 Query: 507 AVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQ 561 AVC CS+ G H+ TFDG+ Y F C Y+ + + S G+F++ +N PCG Sbjct: 854 AVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTT- 912 Query: 562 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDD---AFEIRRLSSVFLRV 618 C +++ + + + ++ L D+++++ + A+ R + +L V Sbjct: 913 GVTCSKAIKIFMGRT-----------ELKLEDKHRVVIQRDEGHHVAYTTREVGQ-YLVV 960 Query: 619 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 678 ++ G+ V++D+ +++++ + GLCG F+ + +DF + + S+ FGN Sbjct: 961 ESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGN 1019 Query: 679 SWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 738 SWK C P VS +P +PC ++ S++ + CS+L +F+ C + + P P++E C Sbjct: 1020 SWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVH 1077 Query: 739 DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSC-------EASKEYSP 787 D+C C C C+ +A YA C + G V +R C + C E Y P Sbjct: 1078 DSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTP-DLCPIFCDYYNPPHECEWHYEP 1136 Query: 788 CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPPDTYL-DTQADLCVPRNQCS 844 C TC+ + G+ +S +EGC CP D + + CV ++C Sbjct: 1137 CGNRSFETCRTIN-----GIHSNISVSY---LEGCYPRCPKDRPIYEEDLKKCVTADKCG 1188 Query: 845 CHFQGVDYPPGDSDIPSLGHC 865 C+ + YPPG S +P+ C Sbjct: 1189 CYVEDTHYPPGAS-VPTEETC 1208 Score = 248 bits (632), Expect = 8e-65 Identities = 316/1346 (23%), Positives = 474/1346 (35%), Gaps = 216/1346 (16%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 3797 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3856 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 3857 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3906 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 3907 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3966 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 3967 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 4023 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 4024 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4083 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 4084 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4136 Query: 1826 TSAPVATPGPKASVITTPLQPQAT--------------TLPAQTLSPVLPFTPAAMTQAH 1871 T P TP + TTP+ T T P T + V P TQ Sbjct: 4137 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTG 4196 Query: 1872 PPTHIA-----------PPAAGTAPGLLLGATLP---TSGVLPVAEGTASMVSVVPRKST 1917 PPTH + PP + P + P ++ +L M S P + Sbjct: 4197 PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTP 4256 Query: 1918 TGKVAILSKQ-VSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQAGTALPVPTSY 1975 T +S P S S G PT T +S TP + A T P P S Sbjct: 4257 TAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLST 4316 Query: 1976 ALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDEATTEPSGRSA 2026 + P S +++ L + + GT T E S Sbjct: 4317 PSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSC 4376 Query: 2027 PALSIVEGLAEALATTTEANTSTTCVPIAEQ---------------------DCVRHICL 2065 P+ T +ST P DC C Sbjct: 4377 PSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCK 4436 Query: 2066 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIFPDLSFVTFDG 2124 + + + + P P C VRV D CC WEC C C+ + D +VTFDG Sbjct: 4437 YNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDG 4494 Query: 2125 SHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLVMLNMTHLAHQ 2178 + + Y+L + SP +D + + + P C L + H + Sbjct: 4495 LYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQE 4547 Query: 2179 VTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2233 V I + +V V+ Q V P +YG + +G Y++ P + + + Sbjct: 4548 VLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSV 4607 Query: 2234 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------S 2284 G CG C ++D L G +V E A D W V S Sbjct: 4608 RLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVNDPSKPHCPHS 4664 Query: 2285 SLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2339 S T+ P TT DC SP +++ + F+ CH VPP+ + + + D+ ++ Sbjct: 4665 SSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFM 4724 Query: 2340 ---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDG 2394 C +L Y A+C + ++C++WR + C C S YQAC A EP TC+ Sbjct: 4725 PGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEP--TCKSS 4782 Query: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454 ++ VL EGC C EGT+ + +C+ C C VPR GE + Sbjct: 4783 S----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPREFGEHFEFDCK 4836 Query: 2455 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTVCVCNQTLCEG 2513 C + I+ C C+ G +A + D CC TVC CN +LC+ Sbjct: 4837 NCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKE 4894 Query: 2514 LAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQILITGRLGDSCC 2570 C G + + CCP Y CE +C AE P Sbjct: 4895 KPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG----------------S 4937 Query: 2571 TSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEV 2630 Y C DC C + V NT L C + C C G L+E Sbjct: 4938 PVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTSCSPGFELME- 4981 Query: 2631 WSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQLDEEFMHSVEN 2672 +P CC K CE C D + P C + ++ + + SV N Sbjct: 4982 -APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSN 5038 Query: 2673 VCGCAKYECVKAPVCLSRELGVMQPG 2698 + C ++ A +C+ + M G Sbjct: 5039 IT-CPNFD---ASICIPGSITFMPNG 5060 Score = 157 bits (398), Expect = 1e-37 Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%) Query: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 206 C +G H TFDG YY G SY V G++ G SFSI N P CG++ TCS Sbjct: 860 CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 917 Query: 207 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 266 +A+ +F +G E+ L + R + HV + R ++ Y++V + + WD + Sbjct: 918 KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 974 Query: 267 AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 326 V+IK++P G GLCGN + +D T + ++F +SW+E P P Sbjct: 975 TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA----PTCPDV 1030 Query: 327 SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ--SMGDV 384 S+ P P L NP +QC L F CH+ V P PF +C D C + GD Sbjct: 1031 STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 1088 Query: 385 ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIACCPASCH 438 +C A+A YA+ C + G + WRT C + C E + Y C +C Sbjct: 1089 ECFCSAVASYAQECTKEGACVF-WRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1146 Query: 439 PRASCVDS-EIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 490 + ++ ++GCY CP I+E+ CV +C C T YPPG+ V +E Sbjct: 1147 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1206 Query: 491 DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 526 C +C CT+ S VC E G I T DG Sbjct: 1207 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1235 Score = 125 bits (313), Expect = 8e-28 Identities = 141/630 (22%), Positives = 223/630 (35%), Gaps = 66/630 (10%) Query: 1452 EVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALT 1511 E+ +C +CV + T N T P + + T + P + +TPT T Sbjct: 1870 EINVQCC---ECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT----TT 1922 Query: 1512 PAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLA 1571 P TT VT T P + PT T + +T + P G T++P + +T + Sbjct: 1923 PITTTTT-----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-TQTPTTTPITTTTTV 1976 Query: 1572 IPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAV 1631 P TP P QTPT + TT TV +P T + + P +T Sbjct: 1977 TP-TP----TPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2026 Query: 1632 TVRG---HGSLPVRTT-----PPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAV 1683 T G + P+ TT P P+ T +P++ P+ + ++ +PT +G+ TP Sbjct: 2027 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086 Query: 1684 TKVISRTGVPQPTQAQSASSPSTPLTVAGT-------AAEQVP-VSPLATRSLEIVLSTE 1735 T + T P PT + + +TP+T T Q P +P+ T + T Sbjct: 2087 T---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2143 Query: 1736 KG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLA 1794 G + + P+ + + P P P+ P T + T + P TP T T Sbjct: 2144 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTP------TGTQTPT 2196 Query: 1795 ATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP-- 1852 TP + + P+ +G T+ P+ T P TP + TTP+ T P Sbjct: 2197 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2256 Query: 1853 ------AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1906 T +P+ T T T T + PT P Sbjct: 2257 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316 Query: 1907 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE---LTPATSHPLTPLVAEPEGA 1963 + +V P + TG + ++ T++ + T+ TP T+ P G Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2376 Query: 1964 QAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSG 2023 Q T P+ T+ ++ T Q + T+ P TT P Sbjct: 2377 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPIT 2431 Query: 2024 RSAPALSIVEGLAEALATTTEANTSTTCVP 2053 + TTT T+TT P Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461 Score = 124 bits (310), Expect = 2e-27 Identities = 140/590 (23%), Positives = 213/590 (36%), Gaps = 58/590 (9%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 3705 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 3765 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3814 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 3815 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3874 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 3875 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3931 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 3932 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3991 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 3992 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4044 Query: 1826 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAP 1885 T P TP + TTP+ T P T + T +T T P P Sbjct: 4045 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4104 Query: 1886 GLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTEL 1945 T T P GT + TT + + PT G+ T + Sbjct: 4105 TTTPITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT-GTQTPTTTPI 4155 Query: 1946 TPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVLLPQLAEAHGT 2003 T T+ TP P G Q T P+ T+ ++ T Q +AE + Sbjct: 4156 TTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTS 4212 Query: 2004 SAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 + P + +T+ P S LS L A+ T+ A ST P Sbjct: 4213 NPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 4259 Score = 123 bits (308), Expect = 3e-27 Identities = 142/643 (22%), Positives = 220/643 (34%), Gaps = 62/643 (9%) Query: 1445 PTPQVLDEVTQRCVYLEDCVEPAVWVPTEA--LGNETLPPSQGLPTPSDEEPQLSQESPR 1502 PTP +T PT T+ P+ PTP+ + + Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITT 1949 Query: 1503 TPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TE 1558 T T P TP T P T T P +P TQT P+ T + P T+ Sbjct: 1950 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2009 Query: 1559 SPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRS 1618 +P + +T + P TP P QTPT + TT TV +P T + + Sbjct: 2010 TPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTT 2059 Query: 1619 PPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASPSSRPVASPGAISRSPT 1670 P +T T G + P+ TT P P+ T +P++ P+ + ++ +PT Sbjct: 2060 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2119 Query: 1671 SSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAE-------QVPVS-P 1722 +G+ TP T + T P PT + + +TP+T T Q P + P Sbjct: 2120 PTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2176 Query: 1723 LATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETP 1781 + T + T G + + P+ + + P P P+ P T + T + P TP Sbjct: 2177 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTP 2235 Query: 1782 AAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVIT 1841 T T TP + + P+ +G T+ P+ T P TP + T Sbjct: 2236 ------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289 Query: 1842 TPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATL 1893 TP+ T P T +P+ T T T T + Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349 Query: 1894 PTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE---LTPATS 1950 PT P + +V P + TG + ++ T++ + T+ TP T+ Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409 Query: 1951 HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLA 2010 P G Q T P+ T+ ++ T Q + T+ P Sbjct: 2410 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVTPTPT 2464 Query: 2011 AEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 TT P + TTT T+TT P Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507 Score = 122 bits (306), Expect = 5e-27 Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 2095 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2154 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 2155 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2204 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 2205 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2264 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2321 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 2322 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 2382 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2434 Query: 1826 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1877 T P TP + TTP+ T P T +P+ T T T Sbjct: 2435 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2494 Query: 1878 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1937 T + PT P + +V P + TG + ++ T++ + Sbjct: 2495 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2554 Query: 1938 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1994 T+ TP T+ P G Q T P+ T+ ++ T Q + Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614 Query: 1995 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T+ P TT P + TTT T+TT P Sbjct: 2615 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668 Score = 122 bits (306), Expect = 5e-27 Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 2256 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2315 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 2316 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2365 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 2366 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2425 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 2426 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2482 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 2483 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 2543 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2595 Query: 1826 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1877 T P TP + TTP+ T P T +P+ T T T Sbjct: 2596 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2655 Query: 1878 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1937 T + PT P + +V P + TG + ++ T++ + Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2715 Query: 1938 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1994 T+ TP T+ P G Q T P+ T+ ++ T Q + Sbjct: 2716 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775 Query: 1995 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T+ P TT P + TTT T+TT P Sbjct: 2776 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829 Score = 122 bits (306), Expect = 5e-27 Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2526 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 2527 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2586 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 2587 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2643 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 2644 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2703 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 2704 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756 Query: 1826 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1877 T P TP + TTP+ T P T +P+ T T T Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2816 Query: 1878 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1937 T + PT P + +V P + TG + ++ T++ + Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2876 Query: 1938 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1994 T+ TP T+ P G Q T P+ T+ ++ T Q + Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2936 Query: 1995 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T+ P TT P + TTT T+TT P Sbjct: 2937 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2990 Score = 122 bits (306), Expect = 5e-27 Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 2578 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2637 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 2638 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2687 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 2688 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2747 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 2748 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2804 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 2805 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 2865 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2917 Query: 1826 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1877 T P TP + TTP+ T P T +P+ T T T Sbjct: 2918 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2977 Query: 1878 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1937 T + PT P + +V P + TG + ++ T++ + Sbjct: 2978 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3037 Query: 1938 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1994 T+ TP T+ P G Q T P+ T+ ++ T Q + Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3097 Query: 1995 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T+ P TT P + TTT T+TT P Sbjct: 3098 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151 Score = 122 bits (306), Expect = 5e-27 Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2798 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 2799 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2848 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 2849 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2908 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 2909 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2965 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 3026 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3078 Query: 1826 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1877 T P TP + TTP+ T P T +P+ T T T Sbjct: 3079 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3138 Query: 1878 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1937 T + PT P + +V P + TG + ++ T++ + Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3198 Query: 1938 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1994 T+ TP T+ P G Q T P+ T+ ++ T Q + Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258 Query: 1995 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T+ P TT P + TTT T+TT P Sbjct: 3259 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3312 Score = 122 bits (306), Expect = 5e-27 Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2959 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3009 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 3010 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3069 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3126 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 3127 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3186 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 3187 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3239 Query: 1826 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1877 T P TP + TTP+ T P T +P+ T T T Sbjct: 3240 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3299 Query: 1878 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1937 T + PT P + +V P + TG + ++ T++ + Sbjct: 3300 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3359 Query: 1938 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1994 T+ TP T+ P G Q T P+ T+ ++ T Q + Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3419 Query: 1995 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T+ P TT P + TTT T+TT P Sbjct: 3420 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3473 Score = 122 bits (306), Expect = 5e-27 Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 3121 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3170 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 3171 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3230 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3287 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 3288 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 3348 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3400 Query: 1826 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1877 T P TP + TTP+ T P T +P+ T T T Sbjct: 3401 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3460 Query: 1878 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1937 T + PT P + +V P + TG + ++ T++ + Sbjct: 3461 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3520 Query: 1938 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1994 T+ TP T+ P G Q T P+ T+ ++ T Q + Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580 Query: 1995 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T+ P TT P + TTT T+TT P Sbjct: 3581 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634 Score = 122 bits (306), Expect = 5e-27 Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 3222 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3281 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 3282 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3331 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 3332 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3391 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 3392 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3448 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 3449 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 3509 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3561 Query: 1826 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1877 T P TP + TTP+ T P T +P+ T T T Sbjct: 3562 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3621 Query: 1878 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1937 T + PT P + +V P + TG + ++ T++ + Sbjct: 3622 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3681 Query: 1938 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1994 T+ TP T+ P G Q T P+ T+ ++ T Q + Sbjct: 3682 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741 Query: 1995 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T+ P TT P + TTT T+TT P Sbjct: 3742 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3795 Score = 122 bits (306), Expect = 5e-27 Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 3443 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3492 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 3493 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3552 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 3553 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3609 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 3610 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 3670 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3722 Query: 1826 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1877 T P TP + TTP+ T P T +P+ T T T Sbjct: 3723 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3782 Query: 1878 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1937 T + PT P + +V P + TG + ++ T++ + Sbjct: 3783 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3842 Query: 1938 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1994 T+ TP T+ P G Q T P+ T+ ++ T Q + Sbjct: 3843 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902 Query: 1995 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T+ P TT P + TTT T+TT P Sbjct: 3903 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3956 Score = 122 bits (306), Expect = 5e-27 Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%) Query: 1487 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1545 PTP+ + + T T P TP T P T T P +P TQT P+ Sbjct: 3544 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3603 Query: 1546 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1602 T + P T++P + +T + P TP P QTPT + TT Sbjct: 3604 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3653 Query: 1603 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1654 TV +P T + + P +T T G + P+ TT P P+ T +P Sbjct: 3654 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3713 Query: 1655 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1714 ++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T Sbjct: 3714 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3770 Query: 1715 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1765 Q P + P+ T + T G + + P+ + + P P P+ P Sbjct: 3771 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830 Query: 1766 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1825 T + T + P TP T T TP + + P+ +G T+ P+ Sbjct: 3831 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3883 Query: 1826 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1877 T P TP + TTP+ T P T +P+ T T T Sbjct: 3884 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3943 Query: 1878 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1937 T + PT P + +V P + TG + ++ T++ + Sbjct: 3944 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4003 Query: 1938 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1994 T+ TP T+ P G Q T P+ T+ ++ T Q + Sbjct: 4004 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4063 Query: 1995 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T+ P TT P + TTT T+TT P Sbjct: 4064 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4117 Score = 119 bits (297), Expect = 6e-26 Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%) Query: 475 CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 517 C+++ T+ +VK +C TC++G WEC C+ G Sbjct: 4435 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 4485 Query: 518 DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 575 D H+ TFDG Y++ C Y+L + S S F V + N C N +C +++ ++ H+ Sbjct: 4486 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 4544 Query: 576 DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632 + V + + ++ + PY E+ + ++ +GV V Y+ G Sbjct: 4545 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 4602 Query: 633 LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 690 L +++ R+ +T G CGT T DD + P G S + + W P Sbjct: 4603 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 4662 Query: 691 -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741 S S V + + C ++ +FA C A + P Y++ C D+C Sbjct: 4663 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 4722 Query: 742 -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 799 G CA+L YA LC + + +D+R AC + C + +EY C TC+ Sbjct: 4723 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 4782 Query: 800 ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 855 +S + + VEGC CP T D+CV C C G D P G Sbjct: 4783 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 4828 Query: 856 DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 905 + +C C +G + C S+ P C + VN +D ++ + + Sbjct: 4829 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 4888 Query: 906 T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 955 T C+++ + L + + G CP +G+ HG+A EY Sbjct: 4889 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 4934 Query: 956 PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 986 PG V S C CVC CT PC ++C+ Sbjct: 4935 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 4974 Score = 115 bits (289), Expect = 5e-25 Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%) Query: 146 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 205 E D C WG H TFDGLYY G +Y LV P +F + + N + +C Sbjct: 4476 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 4535 Query: 206 SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 255 R +L E + L K V M+VQ LP+ G Q YV+ + Sbjct: 4536 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 4593 Query: 256 SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 315 ++++G S T G CG DD + SG++ + W Sbjct: 4594 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 4653 Query: 316 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 369 P++P P +SS + P + G ++ C+ + F CHA V P + Sbjct: 4654 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 4713 Query: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 428 +C D C G + C +L YA CAQ L WR C V C ++ E Sbjct: 4714 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 4767 Query: 429 CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 476 AC PA +C +S ++ + V+GC+CP G + + GCV P P E Sbjct: 4768 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 4826 Query: 477 FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 514 F G + DC C C G S +C P CS Sbjct: 4827 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 4855 Score = 113 bits (282), Expect = 3e-24 Identities = 147/644 (22%), Positives = 226/644 (35%), Gaps = 78/644 (12%) Query: 1457 CVYLEDCV---EPAVWVPTEALGNETLPPSQGLPTP----SDEEPQLSQESP---RTPTH 1506 C ++ C+ P P+ + T P P+P + P + SP T T Sbjct: 1389 CWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448 Query: 1507 RPALTPAAPLTTALNPPVTATEEP-VVSPGPTQTTLQQPLELTASQLPAGPTESPASKGV 1565 P TP+ P++T PP T T P +P P TT P T + P P + + Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508 Query: 1566 T--ASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPR 1623 T AS +P T S TP P TT +T + + ++ SPP Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP--- 1565 Query: 1624 FPLMTKAVTVRGHGSLPVRTTPPQPSLTAS--PSSRPVASPGAISRSPTSSGSHKAVLTP 1681 P T S P TTP P++T + P + + P + +P + + T Sbjct: 1566 -PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1624 Query: 1682 AVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGH 1741 +T S T +P T +PS P T T SP T + Sbjct: 1625 PITPPTSTTTLPPTT------TPSPPPTTTTTPPPTTTPSPPTTTT-------------P 1665 Query: 1742 SQPMGSPASPQPHPLPSAP----PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATP 1797 S P+ + +P P PS+P P P TTM T SP P +P + + ++ + P Sbjct: 1666 SPPITTTTTPPPTTTPSSPITTTPSPPT-TTMTTPSPTTTPSSPITTTTTPSSTTTPSPP 1724 Query: 1798 FMSLESTRPSQLLSGLPPDTSL-PLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTL 1856 ++ T PS + PP T++ L TS+P+ T S+ P +TT P Sbjct: 1725 PTTM--TTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPC 1782 Query: 1857 SPVLPFT---PAAMTQAHPP---THIAPPAAGT--APGLLLGATLPTS------GVLPVA 1902 P+ +T + H P T + G A + AT+ G V Sbjct: 1783 VPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVC 1842 Query: 1903 EGTASMVSVVPRKSTTGKVAI-----------LSKQVSLPTSMYGSAEGGPT--ELTPAT 1949 + + ++ + G + + + V+ PT+M + PT TP T Sbjct: 1843 DVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPIT 1902 Query: 1950 SHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHL 2009 + P G Q T P+ T+ ++ T Q + T+ P Sbjct: 1903 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVTPTP 1957 Query: 2010 AAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 TT P + TTT T+TT P Sbjct: 1958 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2001 Score = 106 bits (265), Expect = 3e-22 Identities = 180/770 (23%), Positives = 252/770 (32%), Gaps = 128/770 (16%) Query: 1408 CEWRYDACASPCFQTCRDPRAASCR-DVPRGRSCVPVCPTPQ-VLDEVTQRCVYLEDC-- 1463 CEW Y+ C + F+TCR V C P CP + + +E ++CV + C Sbjct: 1130 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1189 Query: 1464 ------VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQ-LSQESPRTPTHRPALTPAAPL 1516 P VPTE + + EE + L+Q + P + Sbjct: 1190 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1249 Query: 1517 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1576 N T ++ T T P T + PT S + TP Sbjct: 1250 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTV----------LSTTP 1299 Query: 1577 ESSSLP---VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTV 1633 + L + P+ G G ET G+P + RS P L V Sbjct: 1300 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1355 Query: 1634 R---------------GHG--------SLPVRTTPPQPSLTASPSSRPVASPGAISRSPT 1670 + G+G + V P +PS P +P S PT Sbjct: 1356 QCDVSVGFICKNEDQFGNGPFGLCYDYKIRVNCCWPMDKCITTPSP-PTTTP---SPPPT 1411 Query: 1671 SSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEI 1730 S+ + TP+ + T P PT ++PS P+T T SP Sbjct: 1412 STTTLPPTTTPSPPTTTTTT--PPPT-----TTPSPPITTTTTPPPTTTPSP-------- 1456 Query: 1731 VLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTAT 1790 +ST + P +P P +PP T T +P+ P TP ST T Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516 Query: 1791 DGLAATPF-MSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKASVITTPLQPQ 1847 TP + +T P + PP T+ P T P TP P + TTP P Sbjct: 1517 LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP-PPT 1575 Query: 1848 ATTLPAQTLSPVLP----FTPAAMTQAHPPTHIA---PPAAGTAPGLLLGATLPTSGVLP 1900 T P T +P P TP T PPT PP +P T PTS Sbjct: 1576 TTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL 1635 Query: 1901 VAEGTAS---MVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLV 1957 T S + P +TT S PT+ S T P T+ P +P+ Sbjct: 1636 PPTTTPSPPPTTTTTPPPTTT---------PSPPTTTTPSPPITTTTTPPPTTTPSSPIT 1686 Query: 1958 AEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEP--VD 2015 P P PT+ S ++ T P + P T+ P P Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSST---TTPSPPPTTMTTPSPTTTPSPPTTT 1743 Query: 2016 EATTEPSGRSAPAL------SIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQL 2069 T P+ S+P SI +TTT +T CVP+ G L Sbjct: 1744 MTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTT---PTTPCVPLCN--------WTGWL 1792 Query: 2070 IRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLW--ECACRCSIFPDL 2117 + H P G + GD C P W +CR +++PD+ Sbjct: 1793 DSGKPNFHKPGG-----------DTELIGDVCGPGWAANISCRATMYPDV 1831 Score = 96.3 bits (238), Expect = 4e-19 Identities = 118/550 (21%), Positives = 187/550 (34%), Gaps = 76/550 (13%) Query: 1515 PLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1574 P+ LN + V+ T TT T ++ P PT +P + T Sbjct: 1862 PMAFCLNYEINVQCCECVTQPTTMTT-------TTTENPTPPTTTPITTTTTV------- 1907 Query: 1575 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVR 1634 TP + P QTPT + TT TV +P T + + P +T TV Sbjct: 1908 TPTPT--PTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTP------ITTTTTV- 1953 Query: 1635 GHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1694 T P P+ T +P++ P+ + ++ +PT +G+ TP T + T P Sbjct: 1954 --------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPT 2002 Query: 1695 PTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH 1754 PT + + +TP+T T V +P T + + + P+ + + P Sbjct: 2003 PTPTGTQTPTTTPITTTTT----VTPTPTPTGT----------QTPTTTPITTTTTVTPT 2048 Query: 1755 PLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLP 1814 P P+ P T + T + P TP T T TP + + P+ +G Sbjct: 2049 PTPTGTQTPTT-TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQ 2101 Query: 1815 PDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAA 1866 T+ P+ T P TP + TTP+ T P T +P+ T Sbjct: 2102 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2161 Query: 1867 MTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSK 1926 T T T + PT P + +V P + TG + Sbjct: 2162 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2221 Query: 1927 QVSLPTSMYGSAEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSAR 1983 ++ T++ + T+ TP T+ P G Q T P+ T+ ++ Sbjct: 2222 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2281 Query: 1984 TAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTT 2043 T Q + T+ P TT P + TTT Sbjct: 2282 TGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2336 Query: 2044 EANTSTTCVP 2053 T+TT P Sbjct: 2337 PITTTTTVTP 2346 Score = 75.5 bits (184), Expect = 7e-13 Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%) Query: 976 CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 1033 C C CT +GD HY TFDGL + + G C LV+ S S +F V ++N +C + Sbjct: 4472 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 4531 Query: 1034 MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1083 + C + + + ++ P ++Q V ++ G +V Sbjct: 4532 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 4591 Query: 1084 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1143 P+ + + ++ + ++ G CG T ++ P ++N + W Sbjct: 4592 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 4651 Query: 1144 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1182 + CP + P C +PL C ++ +F Sbjct: 4652 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 4703 Query: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1240 CH +V +Y C+ D+C G EC AS+ AYA C Q + +DWR T C Sbjct: 4704 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 4760 Query: 1241 DCDFFNKVLGKGP 1253 +C + GP Sbjct: 4761 ECPSHREYQACGP 4773 Score = 67.4 bits (163), Expect = 2e-10 Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%) Query: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2160 C C CSI+ ++TFDG + Y+ Q C ++++LG Sbjct: 851 CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 899 Query: 2161 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2210 F ++ N+ T + I F + + L+ V + + + G Sbjct: 900 ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 955 Query: 2211 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2270 ++ + + I + W + ++ + + K GLCG D + ND T +D VV Sbjct: 956 QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 1014 Query: 2271 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2321 D F +SW+ + V P+ C A CS ++ + FS CH Sbjct: 1015 LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 1064 Query: 2322 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2375 V P+ F E + D+ C A+ Y C K C+ WR D CP C Sbjct: 1065 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1124 Query: 2376 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2426 + C EP +TC+ +GI + + EGC C + ++ Sbjct: 1125 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1180 Query: 2427 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2462 C+ KC C D+ P A T + S C + Q Sbjct: 1181 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1218 Score = 55.8 bits (133), Expect = 6e-07 Identities = 92/411 (22%), Positives = 146/411 (35%), Gaps = 61/411 (14%) Query: 2051 CVPIAEQDCVRH--ICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2108 CVP+++ C H + GQ I N + C A G C C Sbjct: 345 CVPVSQCHCRLHGHLYTPGQEI-TNDCEQCVCNA---------------GRWVCKDLPCP 388 Query: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168 C++ TFDG + Y+L++ + L + A G + Sbjct: 389 GTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHN--DSYALLGELAPCGSTDKQTCLKT 446 Query: 2169 MLNMTHLAHQVTIDRFNRKVTV-DLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQ-WL 2226 ++ + V + + + V + +LQ P V+ + + M+ +++Q L Sbjct: 447 VVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQL 506 Query: 2227 HSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL 2286 + V + S+ Q GLCG +G +D G V A F ++W+ SS Sbjct: 507 APVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSC 563 Query: 2287 TSVGQTRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYV 2339 + + D C+ S C + T F CH V P + + DT Sbjct: 564 HD--KLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNC 621 Query: 2340 QQP----CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTA 2384 Q C AL+ Y C V + WR CP FL + + Q C + Sbjct: 622 QNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSL 681 Query: 2385 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435 E C +G P+D GC C + T L + C+P AKC+C Sbjct: 682 SEADSHCLEG-FAPVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 720 Score = 55.5 bits (132), Expect = 8e-07 Identities = 58/242 (23%), Positives = 93/242 (38%), Gaps = 22/242 (9%) Query: 2203 GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLT 2260 G IE + + + + + + W LM+ +K + H GLCG +G + Sbjct: 125 GLLIEKSDAYTKVYSRAGLTLMWNREDALML---ELDTKFRNHTCGLCGDYNGLQSYSEF 181 Query: 2261 LKDGSVVGGAEDPAPFLDSWQV--PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSA 2318 L DG + P F + ++ P + + P SC+ C R+++ F+ Sbjct: 182 LSDGVLFS----PLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAE-CERLLTAEAFAD 236 Query: 2319 CHRFVPPESFCELWIRDTKYVQ--QPCVALTV--YVAMC-HKFHVCIEWRRSDYCPFLCS 2373 C VP E + +D CV TV + C H WR + CP C Sbjct: 237 CQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCP 296 Query: 2374 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433 + Y + C TC + L EH +GC C EGT+ + C+P ++C Sbjct: 297 GNLVYLESGSPCMD--TCSHLEVSSLCEEHRM---DGCFCPEGTVYDDIGDSGCVPVSQC 351 Query: 2434 AC 2435 C Sbjct: 352 HC 353 Score = 52.8 bits (125), Expect = 5e-06 Identities = 78/325 (24%), Positives = 111/325 (34%), Gaps = 77/325 (23%) Query: 1481 PPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTT 1540 P G TP+ + TPT TP P+T T +P PT T Sbjct: 4142 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTGTQ 4194 Query: 1541 LQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETT 1600 P + + + T +P + T P T S+S P+ T Sbjct: 4195 TGPPTHTSTAPIAELTTSNPPPESST------PQTSRSTSSPL---------------TE 4233 Query: 1601 RVTVIFAGSPNITVSSRSPPA-PRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPV 1659 T++ P I ++S +PP+ P P T GH T P PS T SP Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSG----GH------TLSPPPSTTTSP----- 4278 Query: 1660 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVP 1719 PG +R T++GS A V + P PT STP + T P Sbjct: 4279 --PGTPTRG-TTTGSSSAPTPSTVQTTTTSAWTPTPTPL------STPSIIRTTGLRPYP 4329 Query: 1720 VSPLATRSLEIVLSTEKGEAGHSQPMGS--------------------PASPQPHPLPS- 1758 S L L GE ++ G P++P P P PS Sbjct: 4330 SSVLICCVLNDTYYA-PGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSK 4388 Query: 1759 APPRPAQHTTMATRSP--ALPPETP 1781 + P P++ ++ ++ PPE P Sbjct: 4389 STPTPSKPSSTPSKPTPGTKPPECP 4413 >gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] Length = 2013 Score = 612 bits (1577), Expect = e-174 Identities = 381/1126 (33%), Positives = 548/1126 (48%), Gaps = 65/1126 (5%) Query: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209 +C WG H +TFDG + G +Y + F+IQ+ + S+ T SR Sbjct: 80 VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136 Query: 210 SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 268 L V I L K V G V LP +QQ + Y V + L W+ ++ Sbjct: 137 -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195 Query: 269 YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327 +++ + T GLCG+ N P +L++ + KLT +EF + Q + P Sbjct: 196 LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250 Query: 328 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 384 +P PP +N T G+ CE LL F C A V + +C DLC + + Sbjct: 251 PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304 Query: 385 ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 444 + C LAEY+R C AG Q WR C C Y+EC + C +C + Sbjct: 305 SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362 Query: 445 DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 501 E CV GC+CP G + +D GCV ++C C ++G Y PG+ DC CTC+ G+ Sbjct: 363 ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422 Query: 502 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 561 W C CP CSV G HF+TFDG++YT C Y+L K S FTV + CGL Sbjct: 423 WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482 Query: 562 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 621 C++SV++ L + V + +G+V L Y +P + I R S+ F+ +T+ Sbjct: 483 SETCLKSVTLSL-DGVQTVVVIKASGEVFLNQIYTQLPISAANV-TIFRPSTFFIIAQTS 540 Query: 622 VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 680 +G+++ L ++L++Q+ + T GLCG FN DDF + GV E+T F N++ Sbjct: 541 LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600 Query: 681 KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRR 738 KT +AC P + S DPC + ++ Y+ CS LT F C A + P Y+ C Sbjct: 601 KTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMF 659 Query: 739 DACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACA---LSCEASKEYSPCVAPCG 793 D C C + CLCA L+ Y H C G+ + R C +C S Y V+ C Sbjct: 660 DTCNCERSEDCLCAALSSYVHACAAKGVQLG-GWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718 Query: 794 RTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852 TC+ L+ + C V V+GC CP T+LD CV + C C+ +G Sbjct: 719 PTCRSLSEGDITCSVGFIP-------VDGCICPKGTFLDDTGK-CVQASNCPCYHRGSMI 770 Query: 853 PPGDSDIPSLGHCHCKDGVMSC-DSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQL 911 P G+S S C C G +SC +APA C A VF +C + C++ Sbjct: 771 PNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPG---DTGAGCQKSC 827 Query: 912 LNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVC 969 L ++ P C+ GC CP GL+ G+ C E+CPC Y G + C+TC C Sbjct: 828 HTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887 Query: 970 QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVI 1023 ++CT PC +TC YGD HY TFDG + F G C+ LV K ++ SF V+ Sbjct: 888 DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947 Query: 1024 VENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESF-LDDKQEV-HTWRVGFFTLV 1081 ENV C ++G C K I I +G F+ + E D+ QEV +T R LV Sbjct: 948 TENVPCGTTGTTCSKAIKIFLGG----FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLV 1003 Query: 1082 HFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGS 1141 + LLWD++T++ + P+++G++ GLCGNFD +N+ T + + EFG+ Sbjct: 1004 VDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGN 1063 Query: 1142 SWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200 SW + CPD L P+D C NP R+ +A+K+CSIL F CH V+ +Y C+ D Sbjct: 1064 SWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDA 1123 Query: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246 C C GGDCECFC +V+AYA C + G+ V WRTP +CP CD++N Sbjct: 1124 CACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYN 1169 Score = 231 bits (590), Expect = 6e-60 Identities = 152/486 (31%), Positives = 221/486 (45%), Gaps = 62/486 (12%) Query: 431 ACCPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVV 488 A C SCH +C + CV GC CP+GL+ + +GGC+ +CPC + Y G + Sbjct: 821 AGCQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 878 Query: 489 KEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG-- 546 + CNTCTC S W C+ C A C+V GD H+ TFDG+ Y+F C+Y L ++ G Sbjct: 879 RVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKD 938 Query: 547 ----TFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYT 602 +F V +N PCG C +++ + L G L K+ T Sbjct: 939 STQDSFRVVTENVPCGTTGT-TCSKAIKIFL------------GGFELKLSHGKVEVIGT 985 Query: 603 DDAFEIR---RLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 659 D++ E+ R ++L V T++G+ +L+D++ +++ + + GLCG F+ Sbjct: 986 DESQEVPYTIRQMGIYLVVDTDIGLVLLWDKK-TSIFINLSPEFKGRVCGLCGNFDDIAV 1044 Query: 660 DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 719 +DF + FGNSWK +C ++ P DPC + S++ + CS+L G Sbjct: 1045 NDFATRSRSVVGDVLEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1102 Query: 720 FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 775 FA C A + P Y+E C DAC C C C +A YA C GL V +R C Sbjct: 1103 FAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SIC 1161 Query: 776 ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 826 L C+ Y PC PC RTC++ GD L +EGC CPP Sbjct: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRN---------PRGDCLRDVWGLEGCYPKCPP 1212 Query: 827 DT-YLDTQADLCV-----PRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSR 877 + D CV P CH G Y PG + +PS +C C + + C + Sbjct: 1213 EAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPG-AVVPSDKNCQSCLCTERGVECTYK 1271 Query: 878 APAAAC 883 A A C Sbjct: 1272 AEACVC 1277 Score = 184 bits (468), Expect = 9e-46 Identities = 136/449 (30%), Positives = 201/449 (44%), Gaps = 68/449 (15%) Query: 125 CDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH--- 181 CD R + T C + C +G H TFDG Y +G YTLV H Sbjct: 887 CDSRMWRCTDDPCL----------ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGG 936 Query: 182 -EPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRV-------Q 233 + SF + N P CG++ TCS+A+ +F G + +++HG + V + Sbjct: 937 KDSTQDSFRVVTENVP-CGTTGTTCSKAIKIFLGGFE-----LKLSHGKVEVIGTDESQE 990 Query: 234 LPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293 +P+ ++Q+ Y++V L WD ++++I +SPE G GLCGN + + Sbjct: 991 VPYT-----IRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVN 1045 Query: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL 353 D T S + DV+EF +SW+ P + P+ PC NP +QC L Sbjct: 1046 DFATRSRSVVGDVLEFGNSWKLS-----PSCPDALAPKDPCTA-NPFRKSWAQKQCSILH 1099 Query: 354 RPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411 P F ACHA+V P + +C +D C S GD +C A+A YA+AC + G + WRT Sbjct: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTP 1158 Query: 412 LRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--CP-NGLI 461 C + C + + Y C C +C +PR C+ ++ ++GCY CP I Sbjct: 1159 -SICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCL-RDVWGLEGCYPKCPPEAPI 1216 Query: 462 FEDGGCVAPAECP-------CEFHGTLYPPGSVVKED--CNTCTCTSGKWECSTAVCPAE 512 F++ A CP C HG Y PG+VV D C +C CT EC+ Sbjct: 1217 FDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACV 1276 Query: 513 CSVT------GDIHFTTFDGRRYTFPATC 535 C+ GD+ + T DG A C Sbjct: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARC 1305 Score = 79.3 bits (194), Expect = 5e-14 Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%) Query: 2179 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2238 V I V V+ PV P S+ G I+ + + + + W H L++ +K Sbjct: 143 VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202 Query: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298 + + GLCG +G L + + P F + ++ P Sbjct: 203 YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257 Query: 2299 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2352 +T C ++ + FS C V S+ E + DT + C L Y Sbjct: 258 NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317 Query: 2353 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2411 C H + +WR D+CP C ++ Y C + C TC + +HC GC Sbjct: 318 CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372 Query: 2412 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2456 C EGT+L C+P +KCAC + G A G T+++ + C Sbjct: 373 FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416 Score = 72.4 bits (176), Expect = 6e-12 Identities = 78/332 (23%), Positives = 122/332 (36%), Gaps = 44/332 (13%) Query: 2091 GLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2142 G +RVG + C +W C C+++ D ++TFDG + + Y L Q+ Sbjct: 875 GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNH- 933 Query: 2143 EMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPV--WPPVS 2200 D + + C A ++ + F K++ V Sbjct: 934 ----CGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQ 989 Query: 2201 RYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLT 2260 + I G ++ T + + W + + I S K + GLCG D A ND Sbjct: 990 EVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFI-NLSPEFKGRVCGLCGNFDDIAVNDFA 1048 Query: 2261 LKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVSNR 2314 + SVVG D F +SW++ P +L P S A CS ++ Sbjct: 1049 TRSRSVVG---DVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILHGP 1101 Query: 2315 TFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYC 2368 TF+ACH V P + E + D C A+ Y CH+ +C+ WR C Sbjct: 1102 TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSIC 1161 Query: 2369 PFLC-------SSDSTYQACVTACEPPKTCQD 2393 P C + YQ C C +TC++ Sbjct: 1162 PLFCDYYNPEGQCEWHYQPCGVPC--LRTCRN 1191 Score = 70.1 bits (170), Expect = 3e-11 Identities = 148/661 (22%), Positives = 225/661 (34%), Gaps = 108/661 (16%) Query: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2108 T CVP+++ CV N + + P C + GG C C Sbjct: 386 TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431 Query: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168 CS+ F TFDG + + Y+L++ D + + + L CL Sbjct: 432 GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488 Query: 2169 MLNMTHLAHQ-VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2224 + ++ Q V + + + +V ++ P+S I ++I S + +Q Sbjct: 489 SVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548 Query: 2225 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2284 + + L + A K + Q GLCG + A+D G V A A F ++++ + Sbjct: 549 LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604 Query: 2285 SLTSVGQTRFRPDSCATTDCSPCLRMVSNRT-----FSACHRFVPPESFCELWIRDTKYV 2339 + ++ + P S + + S T F CH V P ++ + DT Sbjct: 605 ACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNC 664 Query: 2340 QQP----CVALTVYVAMCHKFHVCIEWRRSDYCP---FLCSSDSTYQACVTACEPPKTCQ 2392 ++ C AL+ YV C V + R C C TY V+ C+P TC+ Sbjct: 665 ERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQP--TCR 722 Query: 2393 DGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSS 2452 G + + +GC+C +GT L + C+ + C C G GE+ + S Sbjct: 723 SLSEGDITCSVGFIPVDGCICPKGTFLD--DTGKCVQASNCPCY-HRGSMIPNGESVHDS 779 Query: 2453 LSGC-CQH---QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2508 + C C H C PV C +P V P G C Q Sbjct: 780 GAICTCTHGKLSCIGGQAPAPV---CAAPM---------VFFDCRNATPGDTGAGC---Q 824 Query: 2509 TLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDS 2568 C L TC YS +C VP C L+ G Sbjct: 825 KSCHTLDMTC------------------YSPQC---------VPGCVCPDGLVADGEG-G 856 Query: 2569 CCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALV 2628 C T+ DCP C EA T + C C +RC C A Sbjct: 857 CITA-----EDCP-----CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPC---LATC 903 Query: 2629 EVWSPDRCCPYK----SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV-CGCAKYECVK 2683 V+ + S DC+ V H K + F ENV CG C K Sbjct: 904 AVYGDGHYLTFDGQSYSFNGDCEYTLVQN-HCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962 Query: 2684 A 2684 A Sbjct: 963 A 963 Score = 59.7 bits (143), Expect = 4e-08 Identities = 104/450 (23%), Positives = 147/450 (32%), Gaps = 73/450 (16%) Query: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVC-PTPQVLDEVTQRCVYLEDCVEP 1466 CEW Y C PC +TCR+PR RDV C P C P + DE +CV C P Sbjct: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV--ATCPTP 1231 Query: 1467 AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1526 + G P G PSD+ Q + L T T Sbjct: 1232 PLPPRCHVHGKSYRP---GAVVPSDKNCQ------------------SCLCTERGVECTY 1270 Query: 1527 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1586 E V Q + + G + T P +P + P Sbjct: 1271 KAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFS 1330 Query: 1587 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPP 1646 TP +V + T S + + PP+ +P T G T+P Sbjct: 1331 FSTPPLVVSSTHTP--------SNGPSSAHTGPPSSAWP------TTAG-------TSPR 1369 Query: 1647 QPSLTASPSSRPVA------SPGAISRSP---TSSGSHKAV--LTPAVTKVISRTGVPQP 1695 TAS S PV SP P T SG + L +V P+ Sbjct: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCES---PRS 1426 Query: 1696 TQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQ---PMGSPASPQ 1752 + ++ +P PL G + P L R+ E Q P+ S Sbjct: 1427 VECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLA--CSTS 1484 Query: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812 P + PP ++ T + P TP SLSTA TP ++ + Sbjct: 1485 SSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTA----RTTPAPGTATSVKKTFSTP 1540 Query: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITT 1842 PP P+ TS+ ++T P SV+++ Sbjct: 1541 SPP----PVPATSTSS-MSTTTPGTSVVSS 1565 Score = 42.4 bits (98), Expect = 0.007 Identities = 51/186 (27%), Positives = 71/186 (38%), Gaps = 33/186 (17%) Query: 1523 PVTATEEPVVSPG--------PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1574 PVT+T PV +P PTQ+T T + + T +P + A H Sbjct: 1848 PVTST--PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA------H 1899 Query: 1575 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAVTV 1633 T ++S P A T P TTR T + SP T S + P+P T + Sbjct: 1900 TTSTTSAPTARTTSAP--------TTRTT---SASPASTTSGPGNTPSPVPTTSTISAPT 1948 Query: 1634 RGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV- 1692 S P +T P T+S +S P S + S T+S + + T S G Sbjct: 1949 TSITSAPTTSTTSAP--TSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006 Query: 1693 --PQPT 1696 P PT Sbjct: 2007 PSPVPT 2012 Score = 41.2 bits (95), Expect = 0.015 Identities = 73/344 (21%), Positives = 117/344 (34%), Gaps = 47/344 (13%) Query: 1583 VALQTPTPGMVSGAMETTRVTVI-FAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPV 1641 VA PTP +TT T + A + T +SR P +VT H + Sbjct: 1687 VATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPT------ATSVTQGTHTTPVT 1740 Query: 1642 RTTPPQPSLTA-----SPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPT 1696 R P+ + T PS P + SG +T++ Sbjct: 1741 RNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRL---------- 1790 Query: 1697 QAQSASSPSTPLTVAGTAAEQVPVSPLATRS------LEIVLSTEKGEAGHSQPMGSPAS 1750 Q ++ S P + G + L R+ ++ L+ E P G P + Sbjct: 1791 QCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT 1850 Query: 1751 PQPHPLPSAPP-------------RPAQHTTMATRSPALPPETPAAASLSTATDGLAATP 1797 P PS P + ++ TT+ T S P+T + +T+T Sbjct: 1851 STPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTAR 1910 Query: 1798 FMSLESTR-----PSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP 1852 S +TR P+ SG P +T P+ T + T A +T P ++T Sbjct: 1911 TTSAPTTRTTSASPASTTSG-PGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTS 1969 Query: 1853 AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTS 1896 A T S T + + T AP + T+ + +PT+ Sbjct: 1970 APTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013 Score = 39.3 bits (90), Expect = 0.058 Identities = 47/167 (28%), Positives = 64/167 (38%), Gaps = 21/167 (12%) Query: 1826 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPA----AMTQAHPPTHIAPPAA 1881 TS PV P + +P Q ++ ++T + V T + + T AH + + P A Sbjct: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909 Query: 1882 GT--APGLLLGATLPTS-----GVLPVAEGTASMVSV-------VPRKSTTGKVAILSKQ 1927 T AP + P S G P T S +S P STT A S Sbjct: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS--APTSST 1967 Query: 1928 VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS 1974 S PT+ SA T +P TS P + G T PVPT+ Sbjct: 1968 TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG-PGTTPSPVPTT 2013 Score = 35.8 bits (81), Expect = 0.64 Identities = 43/169 (25%), Positives = 59/169 (34%), Gaps = 13/169 (7%) Query: 1479 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1538 T P + S + S + RT T T + P T+ T+T + PT Sbjct: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST-----TSAPTA 1909 Query: 1539 TTLQQPLELTASQLPAGPTESPA---SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSG 1595 T P T S PA T P S T S ++ P T +S P T P + Sbjct: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAP-TTSITSAPTTSTTSAPTSSTT 1968 Query: 1596 AMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1644 + TT T S + + + AP T + G PV TT Sbjct: 1969 SAPTTSTTSAPTSSTTSSPQTSTTSAP----TTSTTSGPGTTPSPVPTT 2013 Score = 32.7 bits (73), Expect = 5.4 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 7/96 (7%) Query: 1796 TPFMSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKA--SVITTPLQPQATTL 1851 TP S+ P+Q PP TS G+SAP +TPG + + TTP AT++ Sbjct: 1477 TPLACSTSSSPAQTT---PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSV 1533 Query: 1852 PAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGL 1887 +P P PA T + T + P L Sbjct: 1534 KKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTL 1569 >gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] Length = 5765 Score = 574 bits (1479), Expect = e-163 Identities = 348/1128 (30%), Positives = 539/1128 (47%), Gaps = 72/1128 (6%) Query: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209 +C WG H +TFDG + G +Y + F++Q+ GS P V Sbjct: 76 VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRG-LVGSRP-----VV 129 Query: 210 SLFFVGEQEIHLAKE---VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 266 + + Q + L V G R +LP+ ++Q Y+ V + T W+G Sbjct: 130 TRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGED 189 Query: 267 AVYIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPT 325 + +++ P+ T GLCG+ N P ++ + +LT ++F + + P + P Sbjct: 190 SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKLDGPTEQC-PD 246 Query: 326 TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVA 385 LP C + +G+ + LL P F CHA V + A+C DLC+ Sbjct: 247 PLPLPAGNCTDE-----EGICHR--TLLGPAFAECHALVDSTAYLAACAQDLCRCP---T 296 Query: 386 TWCRALAEYARACAQAGRPLQGWRTQL---RQCTVHCKEKAFTYNECIACCPASCHPRAS 442 C EY+R CA AG + WR R C ++ + + EC + C +C Sbjct: 297 CPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQ-----HQECGSPCTDTCSNPQR 351 Query: 443 CVDSEIACVDGCYCPNG---LIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCT 496 E CVDGC+CP G + +D GC+ +CPC G Y PG+ C++CT Sbjct: 352 AQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCT 411 Query: 497 CTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAP 556 C+ G W+C CP CSV G H +T+D + Y C Y+L+K + +FTV + Sbjct: 412 CSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRK 471 Query: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616 CGL + C+++V++ L + + G V L Y +P + + SS F+ Sbjct: 472 CGLTDNENCLKAVTLSLDGGDTA-IRVQADGGVFLNSIYTQLPLSAAN-ITLFTPSSFFI 529 Query: 617 RVRTNVGVRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 675 V+T +G+++L L ++++++D GLCG FN N DDF + GV E+T Sbjct: 530 VVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAA 589 Query: 676 FGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLT--GEMFAPCSAFLSPVPYF 733 F N+WK +AC+ S DPC + ++ +Y+ CS LT F+ C + ++P P+ Sbjct: 590 FANTWKAQAACAN-ARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFH 648 Query: 734 EQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPV-DFRARLPACAL-SCEASKEYSPCV 789 C D C C + CLCA L+ Y H C G+ + D+R + + +C S+ Y+ V Sbjct: 649 SNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVV 708 Query: 790 APCGRTCQDLASPEA-CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848 C TC+ L+ + C V V+GC CP T+L+ A CVP +C C+ Sbjct: 709 DACQPTCRGLSEADVTCSVSFVP-------VDGCTCPAGTFLN-DAGACVPAQECPCYAH 760 Query: 849 GVDYPPGDSDIPSLGHCHCKDGVMSC--DSRAPAAACPAGQVFVNCSDLHTDLELSRERT 906 G PG+ C C G +SC S + C A V+++CS+ + Sbjct: 761 GTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAE--- 817 Query: 907 CEQQLLNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPC 964 C + L V C+SGC CP GL+ G C E+CPC Y PG+ + C Sbjct: 818 CLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDC 877 Query: 965 HTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVS 1019 +TC C+ ++C+ C TC AYGD H+ TFDG + F G+C+ L + +T+ + Sbjct: 878 NTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGT 937 Query: 1020 FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFT 1079 F ++ EN+ C ++G C K I + V + ++ + + D + +G F Sbjct: 938 FRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPPYKIRY-MGIFL 996 Query: 1080 LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEF 1139 ++ + + WD++T+V ++ ++G++ GLCGNFD IN+ T + + EF Sbjct: 997 VIE--THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEF 1054 Query: 1140 GSSWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLT 1198 G+SW + CPD L P+D C NP R+ +A+K+CSIL F C VD T +Y C+ Sbjct: 1055 GNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVN 1114 Query: 1199 DTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246 D C C GGDCECFC +V+AYA C G+ V WRTP CP CDF+N Sbjct: 1115 DACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYN 1162 Score = 237 bits (605), Expect = 1e-61 Identities = 152/481 (31%), Positives = 221/481 (45%), Gaps = 64/481 (13%) Query: 433 CPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKE 490 C SCH C + CV GC CP GL+ + GGC+A +CPC + Y PG ++ Sbjct: 818 CLRSCHTLDVGCFSTH--CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRV 875 Query: 491 DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSS 545 DCNTCTC + +WECS +C C GD HF TFDG RY+F +C+YILA+ + + Sbjct: 876 DCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTH 935 Query: 546 GTFTVTLQNAPCGLNQDGAC------VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP 599 GTF + +N PCG V+S +IL + + V GD P Sbjct: 936 GTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGD----------P 985 Query: 600 PYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 659 PY R +FL + T+ G+ V +DR+ +++++ Q + GLCG F+ N Sbjct: 986 PYKI------RYMGIFLVIETH-GMAVSWDRK-TSVFIRLHQDYKGRVCGLCGNFDDNAI 1037 Query: 660 DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 719 +DF + FGNSWK +C ++ P DPC + S++ + CS+L G Sbjct: 1038 NDFATRSRSVVGDALEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1095 Query: 720 FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 775 FA C + + Y+E C DAC C C C +A YA C GL V +R C Sbjct: 1096 FAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTP-DTC 1154 Query: 776 ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 826 L C+ Y PC APC +TC++ + + G +EGC CPP Sbjct: 1155 PLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPG---------LEGCYPKCPP 1205 Query: 827 -DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH---CHCKDGVMSCDSRAPAAA 882 + + CV QC C+ + +Y + +P+ + C+C + C A Sbjct: 1206 SQPFFNEDQMKCVA--QCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACT 1263 Query: 883 C 883 C Sbjct: 1264 C 1264 Score = 207 bits (528), Expect = 9e-53 Identities = 320/1341 (23%), Positives = 466/1341 (34%), Gaps = 245/1341 (18%) Query: 1473 EALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVV 1532 E T+ ++ T + +P T LT AA T A P T P Sbjct: 4361 ETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTAT----PSS 4416 Query: 1533 SPGPTQ--TTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTP 1590 +PG T T L TAS G T +P+S T +L P T + ++P T T Sbjct: 4417 TPGTTWILTELTTTATTTAS---TGSTATPSSTPGTTWILTEPSTTATVTVPTG-STATA 4472 Query: 1591 GMVSGAMETTRVTVIFAGSPNITVSSRSPP-----APRFPLMTKAVTVRGHGS------- 1638 T V+ A +P +T S +P A P + T S Sbjct: 4473 SSTQATAGTPHVSTT-ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSS 4531 Query: 1639 --------LPVRTTPPQPSLTASPSSRP--VASPGAISRSPTSSGSHKAVLTPAVTKVIS 1688 L TTP TA+PSS P V + ++ + T++G+ +V TP+ T + Sbjct: 4532 SLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTA 4591 Query: 1689 RTG-VPQPTQ----AQSASSPSTPLTV-AGTAAEQVPVSPLATRSLEIVLSTEKGEAGHS 1742 T VP T A +SSP T LT + P + T S V + H+ Sbjct: 4592 HTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHT 4651 Query: 1743 QPM----------GSPASPQPHPLPSAPPRPAQHTTM----ATRSPALPPETPAAASLST 1788 + GS A+P S P P+ TT AT S P TP ++ Sbjct: 4652 ARVLTTTTTTVATGSMATPSSSTQTSGTP-PSLTTTATTITATGSTTNPSSTPGTTPITP 4710 Query: 1789 ATDGLAATPFMSLESTRPS---QLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQ 1845 A TP + S + + LP TS TS TP P +++ TT Sbjct: 4711 VLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSF---TPIPSSTLWTTWTV 4767 Query: 1846 PQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGT-------APGLLLGATLPTSGV 1898 P TT P T+S + T + H T + A T P LG T + + Sbjct: 4768 PAQTTTPMSTMSTI--HTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTEL 4825 Query: 1899 LPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSH------- 1951 A TA+ S ST G IL++ ++ T M + T T+H Sbjct: 4826 TTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTT 4885 Query: 1952 ----PLTPLVAEPEGAQAGTA-LPVPTSYALSRVSARTAPQDSMLVLLPQ---------- 1996 P P + GT P +L S T + L P Sbjct: 4886 MATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTP 4945 Query: 1997 -LAEAHGTSAGP-HLAAEPVDEA----------------------TTEPSGRSAPALSIV 2032 A G P + D A T+ P SAP Sbjct: 4946 CFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAP----- 5000 Query: 2033 EGLAEALATTTEANTSTTCVPIAE-------QDCVRHICL-EGQLIRVNQSQHCPQGAAP 2084 L++ + A +P+ + ++C C+ + +++ ++ P+ A Sbjct: 5001 ------LSSPSPAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLD-----PKPVAN 5049 Query: 2085 PRCGILGLAVRVG--GDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2142 C L ++V C +EC C CS++ + TFDG+ Y+L + Sbjct: 5050 VTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIH 5109 Query: 2143 EM---LTVHVLD---CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVW 2196 L++++ + SA P + + VT+ + + + Sbjct: 5110 ARFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQI- 5168 Query: 2197 PPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQ---------GHGL 2247 PVS GF G + +L + +++ + + G+ + + +A+ G Sbjct: 5169 -PVSS-GF--SKNGVLVSVLGTTTMRVD-IPALGVSVTFNGQVFQARLPYSLFHNNTEGQ 5223 Query: 2248 CGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC-------- 2299 CG C + +D +DG+ +D A +W VP S R D C Sbjct: 5224 CGTCTNNQRDDCLQRDGTTAASCKDMAK---TWLVPDS---------RKDGCWAPTGTPP 5271 Query: 2300 ------------ATTDCSP---CLRMVSNRTFSACHRFVPPESFCELWIRD--TKYVQQP 2342 T C P C M+S + F+ CH VPP F I D ++ P Sbjct: 5272 TASPAAPVSSTPTPTPCPPQPLCDLMLS-QVFAECHNLVPPGPFFNACISDHCRGRLEVP 5330 Query: 2343 CVALTVYVAMCHKFHVCIEWRRSD--YCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD 2400 C +L Y +C VC +WR + C C Y+ C P TC P Sbjct: 5331 CQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPI--QPATCNSRNQSP-- 5386 Query: 2401 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ 2460 + + EGC C E IL H +C+ C C G P+ GE W S+ C + Sbjct: 5387 --QLEGMAEGCFCPEDQILFNAHMGICVQA--CPCVGPDGFPKFPGERWVSNCQSCVCDE 5442 Query: 2461 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLP-TKDPCCLGTVCVCNQTLCEGLAPTCR 2519 P+ +P C R G V + P ++PCC TVCVCN T C P C Sbjct: 5443 GSVSVQCKPLPCDAQG-QPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCP 5501 Query: 2520 PGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGD 2579 PG + +E CCP++ C P LC + G L CT C GD Sbjct: 5502 PGQESICTQEEGDCCPTFRCR--PQLCSYN--GTFYGVGATFPGALPCHMCT---CLSGD 5554 Query: 2580 CPDSIPECQEGEALTVHRNTTELCCP--------LYQCVCENFRCPQVQC----GLGTAL 2627 D +CQE NTT CP QC E C Q C G L Sbjct: 5555 TQDPTVQCQEDAC----NNTT---CPQGFEYKRVAGQCCGE---CVQTACLTPDGQPVQL 5604 Query: 2628 VEVW---SPDRCCPYKSCECD 2645 E W D C Y CE + Sbjct: 5605 NETWVNSHVDNCTVY-LCEAE 5624 Score = 137 bits (344), Expect = 2e-31 Identities = 116/411 (28%), Positives = 177/411 (43%), Gaps = 42/411 (10%) Query: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 206 C A+G H TFDG Y G Y L G + G +F I N P CG++ TCS Sbjct: 898 CVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHG-TFRIVTENIP-CGTTGTTCS 955 Query: 207 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ-QLAGYVIVRHQSAFTLAWDGA 265 +A+ LF + I + G + G + + G +V ++WD Sbjct: 956 KAIKLFVESYELI-----LQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRK 1010 Query: 266 SAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPT 325 ++V+I++ + G GLCGN + + +D T S + D +EF +SW+ P Sbjct: 1011 TSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLS-----PSCP 1065 Query: 326 TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGD 383 + P+ PC NP +QC L P F AC + V + +C +D C S GD Sbjct: 1066 DALAPKDPCTA-NPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGD 1124 Query: 384 VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK------AFTYNECIACCPASC 437 +C A+A YA+AC AG + WRT C + C + Y C A C +C Sbjct: 1125 CECFCTAVAAYAQACHDAGLCVS-WRTP-DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTC 1182 Query: 438 -HPRASCVDSEIACVDGCY--CPNGL-IFEDGGCVAPAECPC-EFHGTLYPPGSVVK--E 490 +P C+ ++ ++GCY CP F + A+C C + G Y G+ V E Sbjct: 1183 RNPSGHCL-VDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAE 1241 Query: 491 DCNTCTCTSGKWECSTAVCPAECSVTG------DIHFTTFDGRRYTFPATC 535 +C +C CT +C+ ++ C+ D+ + T DG A C Sbjct: 1242 NCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAIC 1292 Score = 132 bits (333), Expect = 4e-30 Identities = 139/540 (25%), Positives = 208/540 (38%), Gaps = 87/540 (16%) Query: 509 CPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQDGA-- 564 C CS+ G H++TFDG YTF C Y+L + + G ++ L N C + A Sbjct: 5074 CECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAA 5133 Query: 565 -CVQSVSV-ILHQDPRRQVTLTQAGD--VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRT 620 C +++S+ D VT+ + ++LFDQ + ++ + + L + +RV Sbjct: 5134 RCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDI 5193 Query: 621 N-VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 679 +GV V ++ + + L + +T G CGT N +DD L G ++ + + Sbjct: 5194 PALGVSVTFNGQVFQARLPYSL-FHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKT 5252 Query: 680 W-----------------KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAP 722 W T S +P+ S PC C ++ ++FA Sbjct: 5253 WLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQVFAE 5304 Query: 723 CSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFR-ARLPACALSCEA 781 C + P P+F C D CR C +L YA LCR G+ D+R A C L+C Sbjct: 5305 CHNLVPPGPFFNACISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPP 5364 Query: 782 SKEYSPCVAPCGRTCQDL-ASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVP 839 +K Y PC TC SP+ G+ EGC CP D L + +CV Sbjct: 5365 TKVYKPCGPIQPATCNSRNQSPQLEGM-----------AEGCFCPEDQILFNAHMGICV- 5412 Query: 840 RNQCSC-HFQGVDYPPGDSDIPSLGHCHCKDGVMS-------CDSRAPAAACPAGQVFVN 891 C C G PG+ + + C C +G +S CD++ C N Sbjct: 5413 -QACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPPC-------N 5464 Query: 892 CSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQG-----LLRHGDAC--FLPEE 944 T E C + + + + P S CP G GD C F Sbjct: 5465 RPGFVTVTRPRAENPCCPETVCVCNTTTCP-QSLPVCPPGQESICTQEEGDCCPTFRCRP 5523 Query: 945 CPCTWKGKEY-----FPGDQVMSPCHTCVCQRG-----SFQCTLHPCASTCTAYGDRHYR 994 C++ G Y FPG PCH C C G + QC C +T G + R Sbjct: 5524 QLCSYNGTFYGVGATFPG---ALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKR 5580 Score = 92.8 bits (229), Expect = 4e-18 Identities = 102/400 (25%), Positives = 149/400 (37%), Gaps = 48/400 (12%) Query: 146 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYT- 204 E + IC WG H TFDG Y G +Y L+ + S+ + N S+ Sbjct: 5073 ECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAA 5132 Query: 205 --CSRAVSLFFVGEQEIHLAKEVTHG---GMRV--QLPHVMGSAR---LQQLAGYVIVRH 254 C RA+S+ + +I L + HG G+ + Q+P G ++ L + G +R Sbjct: 5133 ARCPRALSIHYKS-MDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRV 5191 Query: 255 Q-SAFTLAWDGASAVYIKMSPELL--GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 311 A ++ V+ P L T G CG + +DD + G + Sbjct: 5192 DIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAK 5251 Query: 312 SW-------------QEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGVYEQCEALLRPPF 357 +W P P SS P P PC Q C+ +L F Sbjct: 5252 TWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ---------PLCDLMLSQVF 5302 Query: 358 DACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQL-RQCT 416 CH V P PF +C SD C+ G + C++L YA C G WR C Sbjct: 5303 AECHNLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCD 5359 Query: 417 VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP-NGLIFEDGGCVAPAECPC 475 + C Y C PA+C+ R E +GC+CP + ++F + CPC Sbjct: 5360 LTCPPTK-VYKPCGPIQPATCNSRNQSPQLE-GMAEGCFCPEDQILFNAHMGICVQACPC 5417 Query: 476 EF-HGTLYPPGSVVKEDCNTCTCTSG--KWECSTAVCPAE 512 G PG +C +C C G +C C A+ Sbjct: 5418 VGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQ 5457 Score = 91.3 bits (225), Expect = 1e-17 Identities = 142/537 (26%), Positives = 207/537 (38%), Gaps = 65/537 (12%) Query: 1470 VPTEALGNE-TLPPSQGLP--TPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1526 +P+ LG TLP P T S P + E+ T T LT A T A + T Sbjct: 3072 IPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTST---VLTTKATTTRATSSMST- 3127 Query: 1527 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1586 P +PG T + T + GPT +P+S T +L P T + ++P Sbjct: 3128 ---PSSTPGTTWILTELTTAATTTAA-TGPTATPSSTPGTTWILTEPSTTATVTVPTG-S 3182 Query: 1587 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPP 1646 T T T +V A +P + +SSR+ P+ T +R TTP Sbjct: 3183 TATASSTRATAGTLKVLTSTATTPTV-ISSRATPSSSPGTATALPALRS-----TATTPT 3236 Query: 1647 QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTG---VPQPTQAQSASS 1703 S+TA PSS + +S++ T + + + TP+ T T T ++ S Sbjct: 3237 ATSVTAIPSSSLGTAWTRLSQTTTPTAT-MSTATPSSTPETVHTSTVLTTTTTTTRATGS 3295 Query: 1704 PSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPL-PSAPPR 1762 +TP + GTA + ++ +T G + P SP + P+ S Sbjct: 3296 VATPSSTPGTA-----------HTTKVPTTTTTGFT--ATPSSSPGTALTPPVWISTTTT 3342 Query: 1763 PAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLA 1822 P T +T +P+ P T A++ T T AT M+ S+ S SG PP SL Sbjct: 3343 PT--TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSS--STQTSGTPP--SLTTT 3396 Query: 1823 KVGTSAPVATPGPKASVITTPLQPQAT---TLPAQTLSPVLPFTPAAMTQAHPPTHIAPP 1879 +A +T P ++ TTP+ P T T PA T S V P + T P P Sbjct: 3397 ATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP----VPN 3452 Query: 1880 AAGTAPGLLLGATLP----------TSGVLPVAEGT-ASMVSVVPRKSTTGKVAILSKQV 1928 T G L + P TSG+L T S V+ +TT + + Sbjct: 3453 TTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPAL 3512 Query: 1929 SLPTSMYGSAEGGPTELTPATSH----PLTPLVAEPEGAQAGTALP-VPTSYALSRV 1980 S P + E P+ T H T A P + T LP PTS ++ V Sbjct: 3513 SSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTV 3569 Score = 89.0 bits (219), Expect = 6e-17 Identities = 96/386 (24%), Positives = 149/386 (38%), Gaps = 60/386 (15%) Query: 2554 CRQDQILITGRLGDSCCTSYFCACGDCPDSIPE------CQEGEALTVHRNTTELCCPLY 2607 C +DQIL +G C C C PD P+ ++ + + C Sbjct: 5397 CPEDQILFNAHMG--ICVQA-CPCVG-PDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPL 5452 Query: 2608 QCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIP--VPRCHLWEKSQLDEE 2665 C + P + G T + + + CCP C C+ T P +P C ++S +E Sbjct: 5453 PCDAQGQPPPCNRPGFVT-VTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQE 5511 Query: 2666 FMHSVENVCGCAKYECVKAPVCLSR----ELGVMQPGQTVVELSADGVCHTSRCTT--VL 2719 E C C + C + +C +G PG CH C + Sbjct: 5512 -----EGDC-CPTFRC-RPQLCSYNGTFYGVGATFPGAL--------PCHMCTCLSGDTQ 5556 Query: 2720 DPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGA 2779 DP + + C Q +E+ R CCG C +CL P+G Sbjct: 5557 DPTVQCQEDACNNTTCP------QGFEYKRVAGQCCGECVQTACL--TPDGQPVQL--NE 5606 Query: 2780 SW----IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKED 2835 +W + +C + C + +L P SCP ++ GS+ + GCC +C+ED Sbjct: 5607 TWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCR-----GSLRKT--GCCYSCEED 5659 Query: 2836 GRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQR 2895 SC +V I TI ++ T VN+ C+G CP AS Y+ C CC+E + Sbjct: 5660 --SC-QVRINTTILWHQ-GCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHE 5715 Query: 2896 RSVQLFCATNATWVPYTVQEPTDCAC 2921 +V L C N + + +T +C C Sbjct: 5716 ETVPLHC-PNGSAILHTYTHVDECGC 5740 Score = 80.9 bits (198), Expect = 2e-14 Identities = 102/416 (24%), Positives = 154/416 (37%), Gaps = 67/416 (16%) Query: 2091 GLAVRVGGDRCC---PLWECACR-----CSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2142 G +RV + C WEC+ R C + D F+TFDG + YIL+Q Sbjct: 870 GETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYC 929 Query: 2143 EMLTVH-VLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSR 2201 T H + N+ C + + ++++ + K PP Sbjct: 930 GDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPP--- 986 Query: 2202 YGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTL 2261 ++I G +++++ + + W + + I + K + GLCG D +A ND Sbjct: 987 --YKIRYMG-IFLVIETHGMAVSWDRKTSVFI-RLHQDYKGRVCGLCGNFDDNAINDFAT 1042 Query: 2262 KDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVSNRT 2315 + SVVG D F +SW++ P +L P S A CS ++ T Sbjct: 1043 RSRSVVG---DALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILHGPT 1095 Query: 2316 FSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCP 2369 F+AC V + E + D C A+ Y CH +C+ WR D CP Sbjct: 1096 FAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCP 1155 Query: 2370 FLC-------SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQV---LGEGCV--CSEGT 2417 C + YQ C C KTC++ HC V EGC C Sbjct: 1156 LFCDFYNPHGGCEWHYQPCGAPC--LKTCRN------PSGHCLVDLPGLEGCYPKCPPSQ 1207 Query: 2418 ILHRRHSALCIPEAKCACTDSMG--------VPRALG-ETWNSSLSGC-CQHQCQA 2463 C+ A+C C D G VP A ++ N + SG C H +A Sbjct: 1208 PFFNEDQMKCV--AQCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEA 1261 Score = 80.1 bits (196), Expect = 3e-14 Identities = 132/523 (25%), Positives = 191/523 (36%), Gaps = 77/523 (14%) Query: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGS-------------PNITVSSRSP 1619 P TP +SS + TP + + TT T GS P + S + Sbjct: 4232 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT 4291 Query: 1620 PAPRFPLMTKAVTVRGHGSLPVRTT----PPQPSLTASPSS-------------RPVASP 1662 P T + + R +LPV T+ S+T PSS PVA+ Sbjct: 4292 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATM 4351 Query: 1663 GAISRSPTSSGSH-KAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAG--TAAEQVP 1719 I S T +H VLT T + + P+ + T LT A TAA Sbjct: 4352 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4411 Query: 1720 VSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPE 1779 +P +T +L+ A + GS A+P P + +T AT +P Sbjct: 4412 ATPSSTPGTTWILTELTTTATTTASTGSTATPS--STPGTTWILTEPSTTAT--VTVPTG 4467 Query: 1780 TPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPD------TSLPLAKVGTSAPVATP 1833 + A AS + AT A TP +S +T P+ S P T+LP + + P AT Sbjct: 4468 STATASSTQAT---AGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS 4524 Query: 1834 G---PKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1890 P +S+ TT + TT P T+S P + T T A T G Sbjct: 4525 FTAIPSSSLGTTWTRLSQTTTPTATMSTATP----SSTPETVHTSTVLTATATTTGATGS 4580 Query: 1891 ATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQ--VSLPTSMYGSAEGGPTELTPA 1948 P+S GTA + VP +TTG A S +L ++ S PT TP Sbjct: 4581 VATPSS-----TPGTAH-TTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPT 4634 Query: 1949 TS-HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGP 2007 TS +TP +++P T A + T + + GT Sbjct: 4635 TSGSTVTP-----------SSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSL 4683 Query: 2008 HLAAEPVDE--ATTEPSGRSAPALSIVEGLAEALATTTEANTS 2048 A + +TT PS S P + + + + ATT A +S Sbjct: 4684 TTTATTITATGSTTNPS--STPGTTPITPVLTSTATTPAATSS 4724 Score = 76.6 bits (187), Expect = 3e-13 Identities = 118/438 (26%), Positives = 164/438 (37%), Gaps = 44/438 (10%) Query: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAV 1631 P TP +SS TP + TT T GS S+ R+ P P+ L T A Sbjct: 1889 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKV-LTTTAT 1947 Query: 1632 TVRGHGSLPVRTTPPQPSLTASPSSRPVA-SPGAISRSPTSSGS-------HKAVLTPAV 1683 T S ++ P + TA P+ R A +P A S +P S S TP Sbjct: 1948 TPTVTSSKATPSSSP-GTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTA 2006 Query: 1684 TKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVS-PLATRSLEIVLSTEKGEAGHS 1742 T + T S +T T T + P S P + ++ +T G + Sbjct: 2007 TMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFT--A 2064 Query: 1743 QPMGSPASPQPHPL-PSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSL 1801 P SP + P+ S P T +T +P+ P T A++ T T AT M+ Sbjct: 2065 TPSSSPGTALTPPVWISTTTTPT--TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMAT 2122 Query: 1802 ESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQAT---TLPAQTLSP 1858 S+ S SG PP SL +A +T P ++ TTP+ P T T PA T + Sbjct: 2123 PSS--STQTSGTPP--SLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNT 2178 Query: 1859 VLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLP----------TSGVLPVAEGT-AS 1907 V P + T P P T G L + P TSG+L T S Sbjct: 2179 VTPSSALGTTHTPP----VPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPS 2234 Query: 1908 MVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPL----TPLVAEPEGA 1963 V+ +TTG + +S P + E P+ T H T A P Sbjct: 2235 TVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKT 2294 Query: 1964 QAGTALP-VPTSYALSRV 1980 + T LP PTS ++ V Sbjct: 2295 RTSTLLPSSPTSAPITTV 2312 Score = 75.1 bits (183), Expect = 9e-13 Identities = 98/389 (25%), Positives = 155/389 (39%), Gaps = 37/389 (9%) Query: 1503 TPTHRPALTPAAPLTTALNPPVTATE-EPVVSPGPTQTTLQQPLELTASQLPAGPTESP- 1560 T T R A P TTA P VT+++ P SPG T T L P + + P + +P Sbjct: 1930 TSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPG-TATAL--PALRSTATTPTATSVTPI 1986 Query: 1561 --ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRS 1618 +S G T + L+ TP ++ + T TP T+ V A + T S + Sbjct: 1987 PSSSLGTTWTRLSQTTTPTAT-----MSTATPSSTPETAHTSTVLTATATTTGATGSVAT 2041 Query: 1619 PPA-PRFPLMTKAVTVRGHGSLPVRTTPPQPSLT----ASPSSRPVASPGAISRSPTSSG 1673 P + P TK T G ++ P +LT S ++ P ++ S Sbjct: 2042 PSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGT 2101 Query: 1674 SHKA-VLTPAVTKVISRTGVPQPTQAQSASSP----STPLTVAGTAAEQVPVSPLATRSL 1728 +H A VLT T V + + + Q++ +P +T T+ T + P S T + Sbjct: 2102 THTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPI 2161 Query: 1729 EIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETP--AAASL 1786 VL+T + +P+S L + P +T T +LPP +P + Sbjct: 2162 PPVLTTTATTPAATSNTVTPSS----ALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAW 2217 Query: 1787 STATDGLAATPFMSLESTRPSQLLSGLPPDT--SLPLAKVGTSAPVATPGPKASVITTPL 1844 ++AT G+ T ++ ST S L+ T S P + T P + TTP Sbjct: 2218 TSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 2277 Query: 1845 QPQATTLPAQTLSP-------VLPFTPAA 1866 AT+ T +P +LP +P + Sbjct: 2278 HTTATSRTTATATPSKTRTSTLLPSSPTS 2306 Score = 74.7 bits (182), Expect = 1e-12 Identities = 149/651 (22%), Positives = 216/651 (33%), Gaps = 83/651 (12%) Query: 1471 PTEALGNETLPPSQGLPTPSDEEPQLSQESPRTP-THRPALTPAAPLTTALNPPVTATEE 1529 P+ ALG PP T + L SP T T + T TT + P T T Sbjct: 3438 PSSALGTTHTPPVPNT-TATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSH 3496 Query: 1530 PVVSPGPTQTTLQQPLELTASQLPAG-PTESPASKGVTASLLAIPHTPESSSLPVALQTP 1588 +P T +T Q +S P+ TESP S G T P +S A TP Sbjct: 3497 ---TPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTT-----PGHTRGTSRTTATATP 3548 Query: 1589 TPGMVSGAMETTRV-----TVIFAG-SPNITVS-----SRSPPAPRFPLMTKAVTVRGHG 1637 + S + ++ TV+ G P S S P P +R G Sbjct: 3549 SKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAG 3608 Query: 1638 SLPVRT-------TPPQPSLTASPSSRPVASP---GAISRSPTSSGSHKAVLTPAVTKVI 1687 QP + + V G + R+ G K + Sbjct: 3609 GAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFC 3668 Query: 1688 SRTG-VPQPTQAQSASSPS---------TPLTVAGTAAEQV--PVSPLATRSLEIVLSTE 1735 G P S ++PS T LT T E +P +T +L+ Sbjct: 3669 CNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEP 3728 Query: 1736 KGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTM--ATRSPALPPETPAAASLSTATDGL 1793 A + P GS A+ + P + T T S A P +P A+ A Sbjct: 3729 STTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRST 3788 Query: 1794 AATPFMSLESTRPSQLLSGL---PPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATT 1850 A TP + + PS L T+ P A + T+ P +TP + + +T L ATT Sbjct: 3789 ATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP--ETAHTSTVLTTTATT 3846 Query: 1851 LPAQTLSPVLPFTPAAMTQAHPPTHI----------APPAAGTAPGLLLGATLPTSGVLP 1900 A TP PT +P A T P + T PT+ Sbjct: 3847 TRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGST 3906 Query: 1901 VAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEP 1960 V + + P TT + + ++ P+S ++ P+ +T AT+ T P Sbjct: 3907 VTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNP 3966 Query: 1961 EGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTE 2020 T +P + + T P + + P + A GT+ P PV T Sbjct: 3967 SSTPGTTPIPPVLT------TTATTPAATSSTVTP--SSALGTTHTP-----PVPNTTAT 4013 Query: 2021 PSGRSAPALS-------IVEGLAEALATT--TEANTSTTCVPIAEQDCVRH 2062 GRS S + L TT TE +T T+ P A +H Sbjct: 4014 THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH 4064 Score = 73.9 bits (180), Expect = 2e-12 Identities = 147/611 (24%), Positives = 219/611 (35%), Gaps = 107/611 (17%) Query: 1470 VPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEE 1529 +P+ +LG SQ + +P T LT A T A T Sbjct: 2543 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVAT---- 2598 Query: 1530 PVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPES-------SSLP 1582 P +PG TT + L T + A P+ SP + ++ TP + SS+P Sbjct: 2599 PSSTPGTAHTT--KVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIP 2656 Query: 1583 VALQTPTPGMVSGAMETTRVTVIFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGS 1638 TPT + TT T + GS + T +S +PP+ L T A T+ GS Sbjct: 2657 GTTHTPT-------VLTTTTTTVATGSMATPSSSTQTSGTPPS----LTTTATTITATGS 2705 Query: 1639 LPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRT-GVPQPTQ 1697 TT P +++P + P+ P ++ + T+ + + +TP+ + T VP T Sbjct: 2706 ----TTNP----SSTPGTTPI--PPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTA 2755 Query: 1698 AQ--SASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHP 1755 + SPS+P TV TA L T + TE P + + Q Sbjct: 2756 TTHGRSLSPSSPHTVR-TAWTSATSGTLGTTHI-----TEPSTGTSHTPAATTGTTQHST 2809 Query: 1756 LPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPP 1815 + P P+ T T SP P T + +T+ ATP TR S LL P Sbjct: 2810 PALSSPHPSSRT---TESPPSPGTTTPGHTRATSRTTATATP----SKTRTSTLLPSSP- 2861 Query: 1816 DTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTH 1875 TSAP+ T V+T +PQ S +P + Sbjct: 2862 ----------TSAPITT------VVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 2905 Query: 1876 IAPPAAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVS 1929 A A P GL A +P + V E + V + GK + + ++ Sbjct: 2906 AAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIR 2965 Query: 1930 LPTSMYGSAEGGPTELTPATSHPLTPLVAE------PEGAQAGTALPVPTSYALSRVSAR 1983 + YG TPATS TP E A T S A+ + Sbjct: 2966 VFCCNYGHCPS-----TPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPG 3020 Query: 1984 TAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTT 2043 TAP +L T+ P + +AT+ S R+A L + L +T Sbjct: 3021 TAPPPKVLT---------STATTPTATS---SKATSSSSPRTATTLPV-------LTSTA 3061 Query: 2044 EANTSTTCVPI 2054 +T+T+ PI Sbjct: 3062 TKSTATSFTPI 3072 Score = 73.2 bits (178), Expect = 4e-12 Identities = 131/571 (22%), Positives = 204/571 (35%), Gaps = 60/571 (10%) Query: 1470 VPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEE 1529 +P+ +LG SQ + +P T LT A T A T Sbjct: 4528 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVAT---- 4583 Query: 1530 PVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPT 1589 P +PG TT + T + A P+ SP + ++ TP +++ + T T Sbjct: 4584 PSSTPGTAHTT--KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVT 4641 Query: 1590 PGMVSGAMETTRV-----TVIFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGSL- 1639 P + G T RV T + GS + T +S +PP+ L T A T+ GS Sbjct: 4642 PSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPS----LTTTATTITATGSTT 4697 Query: 1640 ----PVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT-PAVTKVISRTGVPQ 1694 TTP P LT++ +P A S TSS S + T P +T +++ Sbjct: 4698 NPSSTPGTTPITPVLTST-----ATTPAATSSKATSSSSPRTATTLPVLTSTATKS---- 4748 Query: 1695 PTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH 1754 T PS+ L T Q +P++T S ST E H+ + + + Sbjct: 4749 -TATSFTPIPSSTLWTTWTVPAQT-TTPMSTMSTIHTSSTP--ETTHTSTVLTTTATMTR 4804 Query: 1755 PLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLP 1814 S + T + T AA+ STAT L++TP + T PS + + + Sbjct: 4805 ATNSTATPSSTLGTTRILTELTTTATTTAATGSTAT--LSSTPGTTWILTEPSTIATVMV 4862 Query: 1815 PDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPT 1874 P S A T TP ++ T P +T + T+ TPA + + P Sbjct: 4863 PTGSTATAS-STLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTR--TPAVLPSSLPTF 4919 Query: 1875 HIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSM 1934 ++ ++ TL +G T + + G+V I +K Sbjct: 4920 SVSTVSSSVL------TTLRPTGFPSSHFSTPCFCRAFGQFFSPGEV-IYNKTDRAGCHF 4972 Query: 1935 YGSAE----------GGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSART 1984 Y PT P +S PL+ P A V ++ L + Sbjct: 4973 YAVCNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGCDNAIPLRQVNETWTLENCTVAR 5032 Query: 1985 APQDSMLVLLPQLAEAHGTSAGPHLAAEPVD 2015 D+ +VLL A+ T HL + D Sbjct: 5033 CVGDNRVVLLDPKPVANVTCVNKHLPIKVSD 5063 Score = 71.6 bits (174), Expect = 1e-11 Identities = 143/597 (23%), Positives = 209/597 (35%), Gaps = 87/597 (14%) Query: 1495 QLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPA 1554 +LSQ + T T A + P T + +TAT + G T P +++P Sbjct: 1997 RLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPT 2056 Query: 1555 ----GPTESPASKGVTASLLAIPHTPESSSLPVAL-QTPTPGMVSGAMET-----TRVTV 1604 G T +P+S TA L P +++ P T TP + G T T T Sbjct: 2057 TTTTGFTATPSSSPGTA--LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTT 2114 Query: 1605 IFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGSL-----PVRTTPPQPSLTASPS 1655 + GS + T +S +PP+ L T A T+ GS TTP P LT + Sbjct: 2115 VATGSMATPSSSTQTSGTPPS----LTTTATTITATGSTTNPSSTPGTTPIPPVLTTT-- 2168 Query: 1656 SRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAA 1715 +P A S + T S + TP V ++ T ++ SSP T T +A Sbjct: 2169 ---ATTPAATSNTVTPSSALGTTHTPPVPNTMATT----HGRSLPPSSPHTVRTAWTSAT 2221 Query: 1716 EQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPA 1775 + + T + T G +Q +PA PHP ++ T SP Sbjct: 2222 SGILGTTHITEPSTVTSHTLAATTGTTQ-HSTPALSSPHP-----------SSRTTESPP 2269 Query: 1776 LPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGP 1835 P T + +T+ ATP TR S LL P TSAP+ T Sbjct: 2270 SPGTTTPGHTTATSRTTATATP----SKTRTSTLLPSSP-----------TSAPITT--- 2311 Query: 1836 KASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAP-GLLLGAT-- 1892 V+T +PQ S +P + A A P GL A Sbjct: 2312 ---VVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQ 2368 Query: 1893 --LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVSLPTSMYGSAEGGPT------ 1943 +P + V E + V + GK + + ++ + YG P Sbjct: 2369 PGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAM 2428 Query: 1944 -ELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHG 2002 TP T+ LT L ++ + P+S T P + V +P + A Sbjct: 2429 PSSTPGTTWILTELTTTATTTESTGSTATPSS-TPGTTWILTEPSTTATVTVPTGSTATA 2487 Query: 2003 TSAGPHLAAEPVDEATTEPSGRSAPALSIVE-GLAEAL-----ATTTEANTSTTCVP 2053 +S V T P+ S+ A G A AL TT TS T +P Sbjct: 2488 SSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIP 2544 Score = 71.2 bits (173), Expect = 1e-11 Identities = 130/553 (23%), Positives = 194/553 (35%), Gaps = 83/553 (15%) Query: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632 P TP +SS TP + T T GS I S+ P L + A T Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3034 Query: 1633 -------VRGHGSLPVRTTPPQPSLTASPSSRPVASP---------GAISRSPTSSGSHK 1676 S TT P + TA+ S+ +P G + T+ + Sbjct: 3035 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094 Query: 1677 AVLTPAVTKVISRTGVPQPTQA---QSASSPSTPLTVAG--------------TAAEQVP 1719 + + P+ T + T T+A ++ SS STP + G TAA Sbjct: 3095 STIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPT 3154 Query: 1720 VSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR---PAQHTTMATRSPAL 1776 +P +T +L+ A + P GS A+ + + T S A Sbjct: 3155 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRAT 3214 Query: 1777 PPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGL---PPDTSLPLAKVGTSAPVATP 1833 P +P A+ A A TP + + PS L T+ P A + T+ P +TP Sbjct: 3215 PSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTP 3274 Query: 1834 GPKASVITTPLQPQATTLPAQTLSPVLP-FTPAAMTQAHPPT----------HIAPPAAG 1882 +V T+ + TT T S P TP PT +P A Sbjct: 3275 ---ETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL 3331 Query: 1883 TAPGLLLGATLPT---SGVLPVA-EGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1938 T P + T PT S V P + GT +V+ +TT + + ++ P+S ++ Sbjct: 3332 TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTT----VATGSMATPSSSTQTS 3387 Query: 1939 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLA 1998 P+ T AT+ T P T +P + + T P + + P + Sbjct: 3388 GTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLT------TTATTPAATSSTVTP--S 3439 Query: 1999 EAHGTSAGPHLAAEPVDEATTEPSGRSAPALS-------IVEGLAEALATT--TEANTST 2049 A GT+ P PV T GRS P S + L TT TE +T T Sbjct: 3440 SALGTTHTP-----PVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVT 3494 Query: 2050 TCVPIAEQDCVRH 2062 + P A +H Sbjct: 3495 SHTPAATTSTTQH 3507 Score = 70.9 bits (172), Expect = 2e-11 Identities = 145/613 (23%), Positives = 214/613 (34%), Gaps = 90/613 (14%) Query: 1479 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEE-------PV 1531 T PS L T Q + + T P+ TP T+ + T T P Sbjct: 3241 TAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPS 3300 Query: 1532 VSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPG 1591 +PG TT + T + A P+ SP + ++ TP + T TP Sbjct: 3301 STPGTAHTT--KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRG-----STVTPS 3353 Query: 1592 MVSGAMET-----TRVTVIFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVR 1642 + G T T T + GS + T +S +PP+ L T A T+ GS Sbjct: 3354 SIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPS----LTTTATTITATGS---- 3405 Query: 1643 TTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRT-GVPQPTQAQSA 1701 TT P +++P + P+ P ++ + T+ + + +TP+ + T VP T Sbjct: 3406 TTNP----SSTPGTTPI--PPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHG 3459 Query: 1702 SS--PSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSA 1759 S PS+P TV TA L T + TE P + ++ Q + Sbjct: 3460 RSLPPSSPHTVR-TAWTSATSGILGTTHI-----TEPSTVTSHTPAATTSTTQHSTPALS 3513 Query: 1760 PPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSL 1819 P P+ T T SP P T + T+ ATP TR S LL P Sbjct: 3514 SPHPSSRT---TESPPSPGTTTPGHTRGTSRTTATATP----SKTRTSTLLPSSP----- 3561 Query: 1820 PLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPP 1879 TSAP+ T V+TT +PQ S +P + A Sbjct: 3562 ------TSAPITT------VVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGG 3609 Query: 1880 AAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVSLPTS 1933 A P GL A +P + V E + V + GK + + ++ + Sbjct: 3610 AVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCC 3669 Query: 1934 MYGSAEGGPT-------ELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAP 1986 YG P TP T+ LT L ++ + P+S T P Sbjct: 3670 NYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSS-TPGTTWILTEP 3728 Query: 1987 QDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVE-GLAEAL-----A 2040 + V +P + A +S V T P+ S+ A G A AL Sbjct: 3729 STTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRST 3788 Query: 2041 TTTEANTSTTCVP 2053 TT TS T +P Sbjct: 3789 ATTPTATSFTAIP 3801 Score = 70.9 bits (172), Expect = 2e-11 Identities = 140/603 (23%), Positives = 210/603 (34%), Gaps = 91/603 (15%) Query: 1470 VPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEE 1529 +P+ +LG SQ + +P T LT A T A T Sbjct: 3800 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVAT---- 3855 Query: 1530 PVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPT 1589 P +PG TT + T + P+ SP + ++ TP +S T T Sbjct: 3856 PSSTPGTAHTT--KVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSG-----STVT 3908 Query: 1590 PGMVSGAMET-----TRVTVIFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1640 P V G T T T + GS + T +S +PP+ L+T A T+ GS Sbjct: 3909 PSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPS----LITTATTITATGS-- 3962 Query: 1641 VRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRT-GVPQPTQAQ 1699 TT P +++P + P+ P ++ + T+ + + +TP+ + T VP T Sbjct: 3963 --TTNP----SSTPGTTPI--PPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATT 4014 Query: 1700 --SASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLP 1757 + SPS+P TV TA L T + TE P + + Q Sbjct: 4015 HGRSLSPSSPHTVR-TAWTSATSGTLGTTHI-----TEPSTGTSHTPAATTGTTQHSTPA 4068 Query: 1758 SAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDT 1817 + P P+ T T SP P T + +T+ ATP TR S LL P Sbjct: 4069 LSSPHPSSRT---TESPPSPGTTTPGHTTATSRTTATATP----SKTRTSTLLPSSP--- 4118 Query: 1818 SLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIA 1877 TSAP+ T V+TT +PQ S +P + A Sbjct: 4119 --------TSAPITT------VVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA 4164 Query: 1878 PPAAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVSLP 1931 A P GL A +P + V E + V + GK + + ++ + Sbjct: 4165 GGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVF 4224 Query: 1932 TSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSML 1991 YG TPATS P + P T L + S S T Sbjct: 4225 CCNYGHCPS-----TPATSSTAMP-SSTPGTTWILTELTTTATTTASTGSTATP------ 4272 Query: 1992 VLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTC 2051 + GT+ P + P T S ++ + L +T +T+T+ Sbjct: 4273 ------SSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSV 4326 Query: 2052 VPI 2054 PI Sbjct: 4327 TPI 4329 Score = 69.7 bits (169), Expect = 4e-11 Identities = 109/448 (24%), Positives = 168/448 (37%), Gaps = 53/448 (11%) Query: 1469 WVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATE 1528 W+ TE T+ +PT S +Q + TP TTA P VT+++ Sbjct: 3723 WILTEPSTTATVT----VPTGSTATASSTQATAGTPHVS---------TTATTPTVTSSK 3769 Query: 1529 -EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASK-GVTASLLAIPHTPESS-SLPVAL 1585 P SPG T T L + T P+S G T + L+ TP ++ S Sbjct: 3770 ATPFSSPG-TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS 3828 Query: 1586 QTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT-- 1643 TP S + TT T GS + S P T G P + Sbjct: 3829 STPETAHTSTVLTTTATTTRATGS---VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPG 3885 Query: 1644 TPPQPSLTASPSSRPVASPGAISRSPTSSGSH-KAVLTPAVTKVISRTGVPQPTQAQSAS 1702 T P + S ++ P S ++ S +H VLT T V + + + Q++ Sbjct: 3886 TARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG 3945 Query: 1703 SP----STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPS 1758 +P +T T+ T + P S T + VL+T + +P+S L + Sbjct: 3946 TPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSS----ALGT 4001 Query: 1759 APPRPAQHTTMATRSPALPPETP--AAASLSTATDGLAATPFMSLESTRPSQLLSGLPPD 1816 P +TT T +L P +P + ++AT G T ++ ST S Sbjct: 4002 THTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSH-------- 4053 Query: 1817 TSLPLAKVGT---SAP-VATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1872 P A GT S P +++P P + +P P TT P T + T A T + Sbjct: 4054 --TPAATTGTTQHSTPALSSPHPSSRTTESPPSP-GTTTPGHTTA--TSRTTATATPSKT 4108 Query: 1873 PTHIAPPAAGTAPGLLLGATLPTSGVLP 1900 T P++ T+ + T+ T+G P Sbjct: 4109 RTSTLLPSSPTSAPI---TTVVTTGCEP 4133 Score = 69.3 bits (168), Expect = 5e-11 Identities = 76/304 (25%), Positives = 111/304 (36%), Gaps = 46/304 (15%) Query: 976 CTLH-PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIVENVNCYSS 1032 C H C C+ +G HY TFDG + F G C L++ + S+ ++N C +S Sbjct: 5068 CDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTAS 5127 Query: 1033 GMI----CRKFISINVGN---------------SLIVFDDDSGNPSPESFLDDKQEVHTW 1073 C + +SI+ + LI+FD P S K V Sbjct: 5128 ATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQ-----IPVSSGFSKNGVLVS 5182 Query: 1074 RVGFFTL-VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF-----------DLKT 1121 +G T+ V P +++ ++ + + G CG D T Sbjct: 5183 VLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTT 5242 Query: 1122 INEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKE-CSILLSEVF 1180 + L WA P T P P P + C ++LS+VF Sbjct: 5243 AASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVF 5302 Query: 1181 EICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLC 1238 CH +V F++ C++D C G E C S+ AYA C GV DWR T LC Sbjct: 5303 AECHNLVPPGPFFNACISDHC----RGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLC 5358 Query: 1239 PYDC 1242 C Sbjct: 5359 DLTC 5362 Score = 68.6 bits (166), Expect = 9e-11 Identities = 147/620 (23%), Positives = 222/620 (35%), Gaps = 95/620 (15%) Query: 1479 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1538 T PP+ L T + Q +P+ PT P LT A PP + T P +S G T Sbjct: 1612 TPPPTTELETATTTTTQALFSTPQ-PTSSPGLTRA--------PPASTTAVPTLSEGLTS 1662 Query: 1539 TTLQQPLELTAS---QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSG 1595 L + PAG TE P GV S L P S+LP +G Sbjct: 1663 PRYTSTLGTATTGGPTTPAGSTE-PTVPGVATSTL-----PTRSALPGT---------TG 1707 Query: 1596 AMETTRVTVIFAGSPNITVSSRSPP------APRFPLMTK-AVTVRGHGSLP-VRTTPPQ 1647 ++ T R + +P +SR+ P A + PL T A T+ S T+ P+ Sbjct: 1708 SLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPR 1767 Query: 1648 PSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVP-------QPTQAQS 1700 T SP + S G P K T +GV + +A Sbjct: 1768 TETTMSPLTNTTTSQGTTRCQP------KCEWTEWFDVDFPTSGVAGGDMETFENIRAAG 1821 Query: 1701 ASSPSTPLTVAGTAAEQVP------VSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH 1754 P ++ AE P V + T SLE L+ + + M + + Sbjct: 1822 GKMCWAPKSIE-CRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVL 1880 Query: 1755 PLPSAPPRPAQHTTMATRSPALPPET------PAAASLSTATDGLAATPFMSLESTRPSQ 1808 P+ T +T +P+ P T P + +TA+ G ATP +L + P + Sbjct: 1881 CCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPK 1940 Query: 1809 LLSGLPPDTSLPLAKVGTSAPVATPGPKA------SVITTPLQPQATTLPAQTLSPV--- 1859 +L+ + P + P ++PG S TTP T +P+ +L Sbjct: 1941 VLT---TTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTR 1997 Query: 1860 --LPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKST 1917 TP A P+ P A T+ +L AT T+G A G+ + S P + Sbjct: 1998 LSQTTTPTATMSTATPSS-TPETAHTS--TVLTATATTTG----ATGSVATPSSTPGTAH 2050 Query: 1918 TGKVAILSKQ--VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSY 1975 T KV + + P+S G+A P ++ T+ P +++P T Sbjct: 2051 TTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTP------SSIPGTTHT 2104 Query: 1976 ALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDE--ATTEPSGRSAPALSIVE 2033 A + T + + GT A + +TT PS S P + + Sbjct: 2105 ATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS--STPGTTPIP 2162 Query: 2034 GLAEALATTTEANTSTTCVP 2053 + ATT A TS T P Sbjct: 2163 PVLTTTATTPAA-TSNTVTP 2181 Score = 68.2 bits (165), Expect = 1e-10 Identities = 92/396 (23%), Positives = 154/396 (38%), Gaps = 32/396 (8%) Query: 1517 TTALNPPVTATE-EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHT 1575 +TA P V ++ P SPG T T L + T P+S TA T Sbjct: 3201 STATTPTVISSRATPSSSPG-TATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTT 3259 Query: 1576 PESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRG 1635 ++++ A + TP V + T T + ++ S +P TK T Sbjct: 3260 TPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAH---TTKVPTTTT 3316 Query: 1636 HGSLPVRTTPPQPSLT----ASPSSRPVASPGAISRSPTSSGSHKA-VLTPAVTKVISRT 1690 G ++ P +LT S ++ P ++ S +H A VLT T V + + Sbjct: 3317 TGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGS 3376 Query: 1691 GVPQPTQAQSASSP----STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMG 1746 + Q++ +P +T T+ T + P S T + VL+T + Sbjct: 3377 MATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTV 3436 Query: 1747 SPASPQPHPLPSAPPRPAQHTTMATRSPALPPETP--AAASLSTATDGLAATPFMSLEST 1804 +P+S L + P +TT T +LPP +P + ++AT G+ T + T Sbjct: 3437 TPSS----ALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI----T 3488 Query: 1805 RPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTP 1864 PS + S P T+ ++ +++P P + +P P TT P T T Sbjct: 3489 EPSTVTSHTPAATTSTTQH--STPALSSPHPSSRTTESPPSP-GTTTPGHTRG--TSRTT 3543 Query: 1865 AAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLP 1900 A T + T P++ T+ + T+ T+G P Sbjct: 3544 ATATPSKTRTSTLLPSSPTSAPI---TTVVTTGCEP 3576 Score = 67.8 bits (164), Expect = 2e-10 Identities = 84/375 (22%), Positives = 135/375 (36%), Gaps = 36/375 (9%) Query: 2111 CSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVML 2170 CS + D + TFDG Y+ S+ + + +G V+ Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP------VVT 130 Query: 2171 NMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSG 2230 + A + ++ N V ++ Q P SR G +E +G + + W + Sbjct: 131 RVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLW-NGED 189 Query: 2231 LMIVEASKTSKAQGHGLCGICDG-DAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2289 ++E Q GLCG +G A N+ + + P F + ++ Sbjct: 190 SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLT-----PLQFGNLQKLDGPTEQC 244 Query: 2290 GQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-KYVQQPCVALTV 2348 P T + C R + F+ CH V ++ +D + PC Sbjct: 245 PDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATFVE 304 Query: 2349 YVAMC-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVL 2407 Y C H WR + CP C + +Q C + C TC + L +HC Sbjct: 305 YSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPC--TDTCSNPQRAQLCEDHCV-- 360 Query: 2408 GEGCVCSEG---TILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC-CQ---HQ 2460 +GC C G T+L + C+P +C CT G + G ++N++ S C C Q Sbjct: 361 -DGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG-GRTYSPGTSFNTTCSSCTCSGGLWQ 418 Query: 2461 CQAPDTIVPVDLGCP 2475 CQ DL CP Sbjct: 419 CQ--------DLPCP 425 Score = 67.8 bits (164), Expect = 2e-10 Identities = 103/429 (24%), Positives = 161/429 (37%), Gaps = 62/429 (14%) Query: 1469 WVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATE 1528 W+ TE T+ +PT S +Q + TP TTA P VT+++ Sbjct: 2466 WILTEPSTTATVT----VPTGSTATASSTQATAGTPHVS---------TTATTPTVTSSK 2512 Query: 1529 -EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASK-GVTASLLAIPHTPESSSLPVALQ 1586 P SPG T T L + T P+S G T + L+ TP ++ + Sbjct: 2513 ATPFSSPG-TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTAT-----MS 2566 Query: 1587 TPTPGMVSGAMETTRV---TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP--- 1640 T TP + T+ V T G+ + S P T G + P Sbjct: 2567 TATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSS 2626 Query: 1641 ---VRTTPPQPSLTASPSSR-----PVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692 RT P S T +P++R P + PG + +PT VLT T V + + Sbjct: 2627 PGTARTLPVWISTTTTPTTRGSTVTPSSIPGT-THTPT-------VLTTTTTTVATGSMA 2678 Query: 1693 PQPTQAQSASSP----STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSP 1748 + Q++ +P +T T+ T + P S T + VL+T + +P Sbjct: 2679 TPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTP 2738 Query: 1749 ASPQPHPLPSAPPRPAQHTTMATRSPALPPETP--AAASLSTATDGLAATPFMSLESTRP 1806 +S L + P +TT T +L P +P + ++AT G T ++ ST Sbjct: 2739 SS----ALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGT 2794 Query: 1807 SQLLSGLPPDT--SLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSP------ 1858 S + T S P + T P + TTP +AT+ T +P Sbjct: 2795 SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTS 2854 Query: 1859 -VLPFTPAA 1866 +LP +P + Sbjct: 2855 TLLPSSPTS 2863 Score = 65.9 bits (159), Expect = 6e-10 Identities = 143/620 (23%), Positives = 221/620 (35%), Gaps = 84/620 (13%) Query: 1477 NETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGP 1536 + TL + G T P LS SP P+ R +P +P TT TAT + P Sbjct: 2238 SHTLAATTG--TTQHSTPALS--SPH-PSSRTTESPPSPGTTTPGH-TTATSRTTATATP 2291 Query: 1537 TQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGA 1596 ++T T++ LP+ PT +P + VT P S L + P P SG Sbjct: 2292 SKTR-------TSTLLPSSPTSAPITTVVTMG--CEPQCAWSEWLDYSYPMPGP---SGG 2339 Query: 1597 METTRVTVIFAGSP----NITVSSRSPPAPRFPLMTKAVTVRGHGSLPV----RTTPPQP 1648 T + AG + + R+ P PL V + R + Sbjct: 2340 DFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKF 2399 Query: 1649 SLTASPSSRPVA-SPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTP 1707 + + R + G +P +S + TP T +++ T +S S +TP Sbjct: 2400 KMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTEL-TTTATTTESTGSTATP 2458 Query: 1708 LTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHT 1767 + GT + P T ++ + P GS A+ + P + Sbjct: 2459 SSTPGTT--WILTEPSTTATVTV-------------PTGSTATASSTQATAGTPHVSTTA 2503 Query: 1768 TM--ATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGL---PPDTSLPLA 1822 T T S A P +P A+ A A TP + + PS L T+ P A Sbjct: 2504 TTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA 2563 Query: 1823 KVGTSAPVATPGP--KASVITTPLQPQATT----LPAQT-----LSPVLPFTPAAMTQAH 1871 + T+ P +TP ++V+TT T P+ T + VL T T A Sbjct: 2564 TMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFT-AT 2622 Query: 1872 PPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLP 1931 P + +P A T P + T PT+ V + + P TT + + ++ P Sbjct: 2623 PSS--SPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATP 2680 Query: 1932 TSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSML 1991 +S ++ P+ T AT+ T P T +P + + T P + Sbjct: 2681 SSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLT------TTATTPAATSS 2734 Query: 1992 VLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALS-------IVEGLAEALATT-- 2042 + P + A GT+ P PV T GRS S + L TT Sbjct: 2735 TVTP--SSALGTTHTP-----PVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 2787 Query: 2043 TEANTSTTCVPIAEQDCVRH 2062 TE +T T+ P A +H Sbjct: 2788 TEPSTGTSHTPAATTGTTQH 2807 Score = 61.2 bits (147), Expect = 1e-08 Identities = 63/260 (24%), Positives = 104/260 (40%), Gaps = 22/260 (8%) Query: 2232 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2291 + V + Q GLCG + + A+D T G V A F ++W+ ++ + Sbjct: 549 VFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATG---AAFANTWKAQAACANARN 605 Query: 2292 TRFRPDSCATTDCSP----CLRMVS-NRTFSACHRFVPPESFCELWIRDTKYVQQP---- 2342 + P S + + + C R+ N FS CH + P+ F + DT ++ Sbjct: 606 SFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCL 665 Query: 2343 CVALTVYVAMCHKFHVCI-EWRRSDYCPFL--CSSDSTYQACVTACEPPKTCQDGILGPL 2399 C AL+ YV C V + +WR ++ C Y V AC+P TC+ + Sbjct: 666 CAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQP--TCRGLSEADV 723 Query: 2400 DPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWN--SSLSGCC 2457 V +GC C GT L+ + C+P +C C + G A GE + ++ C Sbjct: 724 TCSVSFVPVDGCTCPAGTFLN--DAGACVPAQECPCY-AHGTVLAPGEVVHDEGAVCSCT 780 Query: 2458 QHQCQAPDTIVPVDLGCPSP 2477 + + GC +P Sbjct: 781 GGKLSCLGASLQKSTGCAAP 800 Score = 53.5 bits (127), Expect = 3e-06 Identities = 80/355 (22%), Positives = 116/355 (32%), Gaps = 53/355 (14%) Query: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQ-VLDEVTQRCVYLEDCVEP 1466 CEW Y C +PC +TCR+P D+P C P CP Q +E +CV C + Sbjct: 1167 CEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDK 1226 Query: 1467 -------AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP-----AA 1514 VPT G+ E RT +++ + A Sbjct: 1227 DGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGA 1286 Query: 1515 PLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1574 L T + V PG TT P T + +P S S + S + + Sbjct: 1287 CLIAICGSNGTIIRKAVACPGTPATT---PFTFTTAWVP----HSTTSPALPVSTVCVRE 1339 Query: 1575 TPESSSLPVALQTPTPGMVSGAMET--------TRVTVIFAGSPNITVSSRSPPAPRFPL 1626 SS P PG+ G ET +V + A + R+ P PL Sbjct: 1340 VCRWSSWYNG-HRPEPGLGGGDFETFENLRQRGYQVCPVLA-----DIECRAAQLPDMPL 1393 Query: 1627 --MTKAVTVRGHGSLPVRTTPPQPSLTASPSSR----------PVASPGAISRSPTSSGS 1674 + + V L + P L R P +PG + S+ + Sbjct: 1394 EELGQQVDCDRMRGLMCANSQQSPPLCHDYELRVLCCEYVPCGPSPAPGTSPQPSLSAST 1453 Query: 1675 HKAVLTPAVTKVISRTGVPQPTQAQSAS-------SPSTPLTVAGTAAEQVPVSP 1722 AV TP T +T + +S + S S P+TV +A P Sbjct: 1454 EPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSAPGTTTCQP 1508 Score = 49.7 bits (117), Expect = 4e-05 Identities = 97/478 (20%), Positives = 160/478 (33%), Gaps = 76/478 (15%) Query: 1634 RGHGSLPVRTTPPQPSLTASPSS-----RPVASPGAISRSPTSSGSHKAVLTPAVTKVIS 1688 RG + P TT + + T + + +P +SPG ++R+P +S + L+ +T Sbjct: 1607 RGRATTPPPTTELETATTTTTQALFSTPQPTSSPG-LTRAPPASTTAVPTLSEGLTS--- 1662 Query: 1689 RTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSP 1748 P+ T ++ P T AG+ VP +T L G G +P P Sbjct: 1663 ----PRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRP-SQP 1717 Query: 1749 ASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATP-----FMSLES 1803 + P + ++ RP + A++ P P S + + +TP L + Sbjct: 1718 PTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTN 1777 Query: 1804 TRPSQLLSGLPP--------DTSLPLAKVG-----TSAPVATPGPKASVITTPLQPQATT 1850 T SQ + P D P + V T + G K ++ +A Sbjct: 1778 TTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAEN 1837 Query: 1851 LPAQTLSPVLPFTPAAM-----------------------------TQAHPPTHIAPPAA 1881 P ++ V ++ +H P+ A + Sbjct: 1838 YPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSST 1897 Query: 1882 GT---APGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1938 T PG T PT+ A T S + T +L+ + PT S+ Sbjct: 1898 ATPSSTPGTTWILTKPTTTATTTA-STGSTATPTSTLRTAPPPKVLTTTATTPT--VTSS 1954 Query: 1939 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS---YALSRVSARTAPQDSMLVLLP 1995 + P+ +P T+ L L + A + P+P+S +R+S T P +M P Sbjct: 1955 KATPSS-SPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATP 2013 Query: 1996 QLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T H + ATT + S S G A T T T P Sbjct: 2014 S-----STPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATP 2066 Score = 37.7 bits (86), Expect = 0.17 Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 10/83 (12%) Query: 437 CHPRASCVDSEIACVDGC-YCPNG----LIFEDGGCVAPAECP---CEFHGTLYPPGSVV 488 C P CV + C CP G E+G C C C ++GT Y G+ Sbjct: 5480 CCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATF 5539 Query: 489 KE--DCNTCTCTSGKWECSTAVC 509 C+ CTC SG + T C Sbjct: 5540 PGALPCHMCTCLSGDTQDPTVQC 5562 Score = 35.4 bits (80), Expect = 0.83 Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 16/62 (25%) Query: 1411 RYDACASPCFQTCRDP-RAASCRD-------VPRGRSCVPVCPTPQVLDEVTQR-CVYLE 1461 ++ C SPC TC +P RA C D P GRSC VLD++T C+ L Sbjct: 334 QHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCT-------VLDDITHSGCLPLG 386 Query: 1462 DC 1463 C Sbjct: 387 QC 388 >gi|161019170 mucin 5AC [Homo sapiens] Length = 6207 Score = 570 bits (1468), Expect = e-162 Identities = 350/1159 (30%), Positives = 547/1159 (47%), Gaps = 100/1159 (8%) Query: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209 +C WG H +TFDG + G +Y + F++Q+ GS P V Sbjct: 732 VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRG-LVGSRP-----VV 785 Query: 210 SLFFVGEQEIHLAKE---VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 266 + + Q + L V G R +LP+ ++Q Y+ V + T W+G Sbjct: 786 TRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGED 845 Query: 267 AVYIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPT 325 + +++ P+ T GLCG+ N P ++ + +LT ++F + + P + P Sbjct: 846 SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKLDGPTEQC-PD 902 Query: 326 TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVA 385 LP C + +G+ + LL P F CHA V + A+C DLC+ Sbjct: 903 PLPLPAGNCTDE-----EGICHR--TLLGPAFAECHALVDSTAYLAACAQDLCRCP---T 952 Query: 386 TWCRALAEYARACAQAGRPLQGWRTQL---RQCTVHCKEKAFTYNECIACCPASCHPRAS 442 C EY+R CA AG + WR R C ++ + + EC + C +C Sbjct: 953 CPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQ-----HQECGSPCTDTCSNPQR 1007 Query: 443 CVDSEIACVDGCYCPNG---LIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCT 496 E CVDGC+CP G + +D GC+ +CPC G Y PG+ C++CT Sbjct: 1008 AQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCT 1067 Query: 497 CTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAP 556 C+ G W+C CP CSV G H +T+D + Y C Y+L+K + +FTV + Sbjct: 1068 CSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRK 1127 Query: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616 CGL + C+++V++ L + + G V L Y + P + + SS F+ Sbjct: 1128 CGLTDNENCLKAVTLSL-DGGDTAIRVQADGGVFLNSIYTQL-PLSAANITLFTPSSFFI 1185 Query: 617 RVRTNVGVRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 675 V+T +G+++L L ++++++D GLCG FN N DDF + GV E+T Sbjct: 1186 VVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAA 1245 Query: 676 FGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLT--GEMFAPCSAFLSPVPYF 733 F N+WK +AC+ S DPC + ++ +Y+ CS LT F+ C + ++P P+ Sbjct: 1246 FANTWKAQAACAN-ARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFH 1304 Query: 734 EQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPV-DFRARLPACAL-SCEASKEYSPCV 789 C D C C + CLCA L+ Y H C G+ + D+R + + +C S+ Y+ V Sbjct: 1305 SNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVV 1364 Query: 790 APCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848 C TC+ L+ + C V V+GC CP T+L+ A CVP +C C+ Sbjct: 1365 DACQPTCRGLSEADVTCSVSFVP-------VDGCTCPAGTFLN-DAGACVPAQECPCYAH 1416 Query: 849 GVDYPPGDSDIPSLGHCHCKDGVMSC--DSRAPAAACPAGQVFVNCSDLHTDLELSRERT 906 G PG+ C C G +SC S + C A V+++CS+ + Sbjct: 1417 GTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAG---TPGAE 1473 Query: 907 CEQQLLNLSVSARGP-CLSGCACPQGLLRHGD-ACFLPEECPCTWKGKEYFPGDQVMSPC 964 C + L V C+SGC CP GL+ G C E+CPC Y PG+ + C Sbjct: 1474 CLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDC 1533 Query: 965 HTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVS 1019 +TC C+ ++C+ C TC AYGD H+ TFDG + F G+C+ L + +T+ + Sbjct: 1534 NTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGT 1593 Query: 1020 FSVIVENVNCYSSGMICRK----FISINVGNSLIVFDDDSGNPSP-ESFLDDKQEV---- 1070 F ++ EN+ C ++G C K F+ + ++ D + P+P E+ + +Q + Sbjct: 1594 FRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQ 1653 Query: 1071 ---------------------HTWRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQG 1108 +++ + + + H + + WD++T+V ++ ++G Sbjct: 1654 SYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKG 1713 Query: 1109 QLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPF 1167 ++ GLCGNFD IN+ T + + EFG+SW + CPD L P+D C NP R+ + Sbjct: 1714 RVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSW 1773 Query: 1168 AKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHG 1227 A+K+CSIL F C VD T +Y C+ D C C GGDCECFC +V+AYA C G Sbjct: 1774 AQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAG 1833 Query: 1228 VAVDWRTPRLCPYDCDFFN 1246 + V WRTP CP CDF+N Sbjct: 1834 LCVSWRTPDTCPLFCDFYN 1852 Score = 264 bits (675), Expect = 8e-70 Identities = 180/565 (31%), Positives = 268/565 (47%), Gaps = 29/565 (5%) Query: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209 +C WG H +TFDG + G +Y + F+IQ+ + S+ T SR Sbjct: 80 VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136 Query: 210 SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 268 L V I L K V G V LP +QQ + Y V + L W+ ++ Sbjct: 137 -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195 Query: 269 YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327 +++ + T GLCG+ N P +L++ + KLT +EF + Q + P Sbjct: 196 LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250 Query: 328 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 384 +P PP +N T G+ CE LL F C A V + +C DLC + + Sbjct: 251 PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304 Query: 385 ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 444 + C LAEY+R C AG Q WR C C Y+EC + C +C + Sbjct: 305 SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362 Query: 445 DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 501 E CV GC+CP G + +D GCV ++C C ++G Y PG+ DC CTC+ G+ Sbjct: 363 ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422 Query: 502 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 561 W C CP CSV G HF+TFDG++YT C Y+L K S FTV + CGL Sbjct: 423 WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482 Query: 562 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 621 C++SV++ L D + V + +A + +Q P + I R S+ F+ +T+ Sbjct: 483 SETCLKSVTLSL--DGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS 540 Query: 622 VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 680 +G+++ L ++L++Q+ + T GLCG FN DDF + GV E+T F N++ Sbjct: 541 LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600 Query: 681 KTLSACSPLVSGSPLDPCDVHLQAA 705 KT +AC P + S DPC + ++ A Sbjct: 601 KTQAAC-PNIRNSFEDPCSLSVENA 624 Score = 231 bits (589), Expect = 8e-60 Identities = 152/500 (30%), Positives = 233/500 (46%), Gaps = 68/500 (13%) Query: 433 CPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKE 490 C SCH C + CV GC CP GL+ + GGC+A +CPC + Y PG ++ Sbjct: 1474 CLRSCHTLDVGCFSTH--CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRV 1531 Query: 491 DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSS 545 DCNTCTC + +WECS +C C GD HF TFDG RY+F +C+YILA+ + + Sbjct: 1532 DCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTH 1591 Query: 546 GTFTVTLQNAPCGLNQDGAC--------VQSVSVILHQDP--------------RRQVTL 583 GTF + +N PCG V++ + DP R+++ Sbjct: 1592 GTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPP 1651 Query: 584 TQAGDVLLFD-QYKIIP--PYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVD 640 Q+ +++L + +K + P D ++IR + +FL + T+ G+ V +DR+ +++++ Sbjct: 1652 LQSYELILQEGTFKAVARGPGGDPPYKIRYM-GIFLVIETH-GMAVSWDRK-TSVFIRLH 1708 Query: 641 QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDV 700 Q + GLCG F+ N +DF + FGNSWK +C + +P DPC Sbjct: 1709 QDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDAL--APKDPCTA 1766 Query: 701 HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYA 756 + S++ + CS+L G FA C + + Y+E C DAC C C C +A YA Sbjct: 1767 NPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYA 1826 Query: 757 HLCRRHGLPVDFRARLPACALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDG 809 C GL V +R C L C+ Y PC APC +TC++ + + G Sbjct: 1827 QACHDAGLCVSWRTP-DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPG 1885 Query: 810 GDDLSRDECVEGC--ACPP-DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH-- 864 +EGC CPP + + CV QC C+ + +Y + +P+ + Sbjct: 1886 ---------LEGCYPKCPPSQPFFNEDQMKCVA--QCGCYDKDGNYYDVGARVPTAENCQ 1934 Query: 865 -CHCKDGVMSCDSRAPAAAC 883 C+C + C A C Sbjct: 1935 SCNCTPSGIQCAHSLEACTC 1954 Score = 149 bits (376), Expect = 4e-35 Identities = 107/380 (28%), Positives = 163/380 (42%), Gaps = 35/380 (9%) Query: 513 CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDGACVQSVS 570 CS G H+ TFDG + FP C Y+ ++ + F + L+ + Q+ A Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRS-----QESAAPTLSR 135 Query: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630 V++ D V + +L + + ++ P++ I++ SS + +V +G+ ++++ Sbjct: 136 VLMKVDG---VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSS-YTKVEARLGLVLMWNH 191 Query: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV 690 + L L++D ++ T GLCG FNG L + TP FGN K Sbjct: 192 DD-SLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNT-KLTPMEFGNLQKMDDPTEQCQ 249 Query: 691 SGSPLDPCDVHLQAASYSVQACS-VLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ---- 745 P P + S C +L G++F+ C A + Y E CR+D C C Sbjct: 250 DPVPEPP-----RNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304 Query: 746 PCLCATLAHYAHLC-RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 804 C+C TLA Y+ C GLP D+R C C + +Y C +PC TC + A Sbjct: 305 SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363 Query: 805 CGVDGGDDLSRDECVEGCACPPDTYLDTQADL-CVPRNQCSCHFQGVDYPPGDSDIPSLG 863 C D CV GC CP T LD CVP ++C+C + G Y PG + Sbjct: 364 C---------EDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCT 414 Query: 864 HCHCKDGVMSCDSRAPAAAC 883 +C C G SC C Sbjct: 415 NCTCSGGRWSCQEVPCPGTC 434 Score = 144 bits (363), Expect = 1e-33 Identities = 127/443 (28%), Positives = 162/443 (36%), Gaps = 83/443 (18%) Query: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC------ 2299 G CG C + +D +DG+ +D A +W VP S R D C Sbjct: 5556 GQCGTCTNNQRDDCLQRDGTTAASCKDMAK---TWLVPDS---------RKDGCWAPTGT 5603 Query: 2300 --------------ATTDCSP---CLRMVSNRTFSACHRFVPPESFCELWIRD--TKYVQ 2340 T C P C M+S + F+ CH VPP F I D ++ Sbjct: 5604 PPTASPAAPVSSTPTPTPCPPQPLCDLMLS-QVFAECHNLVPPGPFFNACISDHCRGRLE 5662 Query: 2341 QPCVALTVYVAMCHKFHVCIEWRRSD--YCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398 PC +L Y +C VC +WR + C C Y+ C P TC P Sbjct: 5663 VPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPI--QPATCNSRNQSP 5720 Query: 2399 LDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQ 2458 + + EGC C E IL H +C+ C C G P+ GE W S+ C Sbjct: 5721 ----QLEGMAEGCFCPEDQILFNAHMGICVQA--CPCVGPDGFPKFPGERWVSNCQSCVC 5774 Query: 2459 HQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLP-TKDPCCLGTVCVCNQTLCEGLAPT 2517 + P+ +P C R G V + P ++PCC TVCVCN T C P Sbjct: 5775 DEGSVSVQCKPLPCDAQG-QPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPV 5833 Query: 2518 CRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCAC 2577 C PG + +E CCP++ C P LC + G L CT C Sbjct: 5834 CPPGQESICTQEEGDCCPTFRCR--PQLCSYN--GTFYGVGATFPGALPCHMCT---CLS 5886 Query: 2578 GDCPDSIPECQEGEALTVHRNTTELCCP--------LYQCVCENFRCPQVQC----GLGT 2625 GD D +CQE NTT CP QC E C Q C G Sbjct: 5887 GDTQDPTVQCQEDAC----NNTT---CPQGFEYKRVAGQCCGE---CVQTACLTPDGQPV 5936 Query: 2626 ALVEVW---SPDRCCPYKSCECD 2645 L E W D C Y CE + Sbjct: 5937 QLNETWVNSHVDNCTVY-LCEAE 5958 Score = 134 bits (337), Expect = 1e-30 Identities = 147/579 (25%), Positives = 220/579 (37%), Gaps = 108/579 (18%) Query: 474 PCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAE--CSVTGDIHFTTFDGRRYTF 531 PC+FH +C C C G+ + P CS+ G H++TFDG YTF Sbjct: 5386 PCDFH-----------YECE-CECVGGR-----GITPGAGICSMWGGSHYSTFDGTSYTF 5428 Query: 532 PATCQYILAKSRSS--GTFTVTLQNAPCGLNQDGA-----CVQSVSV-ILHQDPRRQVTL 583 C Y+L + + G ++ L N C + A C +++S+ D VT+ Sbjct: 5429 RGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTM 5488 Query: 584 TQAGD--VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVD 640 + ++LFDQ + ++ + + L + +RV +GV V ++ + + L Sbjct: 5489 VHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYS 5548 Query: 641 QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW-----------------KTL 683 + +T G CGT N +DD L G ++ + +W T Sbjct: 5549 L-FHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTA 5607 Query: 684 SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC 743 S +P+ S PC C ++ ++FA C + P P+F C D CR Sbjct: 5608 SPAAPVSSTPTPTPCPPQ--------PLCDLMLSQVFAECHNLVPPGPFFNACISDHCRG 5659 Query: 744 GQPCLCATLAHYAHLCRRHGLPVDFR-ARLPACALSCEASKEYSPCVAPCGRTCQDL-AS 801 C +L YA LCR G+ D+R A C L+C +K Y PC TC S Sbjct: 5660 RLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQS 5719 Query: 802 PEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSC-HFQGVDYPPGDSDI 859 P+ G+ EGC CP D L + +CV C C G PG+ + Sbjct: 5720 PQLEGM-----------AEGCFCPEDQILFNAHMGICV--QACPCVGPDGFPKFPGERWV 5766 Query: 860 PSLGHCHCKDGVMS-------CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 912 + C C +G +S CD++ C N T E C + + Sbjct: 5767 SNCQSCVCDEGSVSVQCKPLPCDAQGQPPPC-------NRPGFVTVTRPRAENPCCPETV 5819 Query: 913 NLSVSARGPCLSGCACPQG-----LLRHGDAC--FLPEECPCTWKGKEY-----FPGDQV 960 + + P S CP G GD C F C++ G Y FPG Sbjct: 5820 CVCNTTTCP-QSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPG--- 5875 Query: 961 MSPCHTCVCQRG-----SFQCTLHPCASTCTAYGDRHYR 994 PCH C C G + QC C +T G + R Sbjct: 5876 ALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKR 5914 Score = 133 bits (334), Expect = 3e-30 Identities = 121/444 (27%), Positives = 183/444 (41%), Gaps = 74/444 (16%) Query: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 206 C A+G H TFDG Y G Y L G + G +F I N P CG++ TCS Sbjct: 1554 CVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHG-TFRIVTENIP-CGTTGTTCS 1611 Query: 207 RAVSLFFVGEQEIHLAKEVTHG--------------GMRVQLPHVMGSARLQQ------- 245 +A+ LF E+ A V+ G R +LP + + Q Sbjct: 1612 KAIKLFV----EVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAV 1667 Query: 246 -------------LAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPK 292 G +V ++WD ++V+I++ + G GLCGN + + Sbjct: 1668 ARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAI 1727 Query: 293 DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL 352 +D T S + D +EF +SW+ P + P+ PC NP +QC L Sbjct: 1728 NDFATRSRSVVGDALEFGNSWK-----LSPSCPDALAPKDPC-TANPFRKSWAQKQCSIL 1781 Query: 353 LRPPFDACHAYVSPLPFTASCTSD--LCQSMGDVATWCRALAEYARACAQAGRPLQGWRT 410 P F AC + V + +C +D C S GD +C A+A YA+AC AG + WRT Sbjct: 1782 HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRT 1840 Query: 411 QLRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--C-PNGL 460 C + C + Y C A C +C +P C+ ++ ++GCY C P+ Sbjct: 1841 P-DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCL-VDLPGLEGCYPKCPPSQP 1898 Query: 461 IFEDGGCVAPAECPC-EFHGTLYPPGSVV--KEDCNTCTCTSGKWECSTAVCPAECSVTG 517 F + A+C C + G Y G+ V E+C +C CT +C+ ++ C+ Sbjct: 1899 FFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTYED 1958 Query: 518 ------DIHFTTFDGRRYTFPATC 535 D+ + T DG A C Sbjct: 1959 RTYSYQDVIYNTTDGLGACLIAIC 1982 Score = 101 bits (251), Expect = 1e-20 Identities = 103/408 (25%), Positives = 156/408 (38%), Gaps = 67/408 (16%) Query: 796 CQDLAS--PEACGVDGG--DDLSRDECVEGCACPPD--TYLDT-QADLCVPRN----QCS 844 CQD P C G ++L + GC D +YL+ + DLC + C Sbjct: 248 CQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCV 307 Query: 845 CHFQGVDYP---------PGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDL 895 CH +Y P D P C + + + R+P C+D Sbjct: 308 CHTLA-EYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP------------CADT 354 Query: 896 HTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHG---DACFLPEECPCTWKGK 952 ++ E SR CE C++GC CP+G + C +C C + G Sbjct: 355 CSNQEHSR--ACEDH-----------CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGA 401 Query: 953 EYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV 1012 Y PG + C C C G + C PC TC+ G H+ TFDG + G C L Sbjct: 402 AYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLT 461 Query: 1013 KSTSDVSFSVIVENVNC-YSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLD----- 1065 K +F+V+ E C + C K +++++ G +V SG E FL+ Sbjct: 462 KPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASG----EVFLNQIYTQ 517 Query: 1066 ---DKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVH--VQAGPQWQGQLAGLCGNFDLK 1120 V +R F ++ + L T+ +Q P+ +GQ GLCGNF+ Sbjct: 518 LPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSI 577 Query: 1121 TINEMRTPEN-LELTNPQEFGSSWAAVECPDTLDP-RDMCVLNPLREP 1166 ++ RT +E T F + CP+ + D C L+ P Sbjct: 578 QADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENAP 625 Score = 91.7 bits (226), Expect = 1e-17 Identities = 100/398 (25%), Positives = 147/398 (36%), Gaps = 50/398 (12%) Query: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHN-----DPQCGSSPYT 204 IC WG H TFDG Y G +Y L+ + S+ + N ++ Sbjct: 5409 ICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAAR 5468 Query: 205 CSRAVSLFFVGEQEIHLAKEVTHG---GMRV--QLPHVMGSAR---LQQLAGYVIVRHQ- 255 C RA+S+ + +I L + HG G+ + Q+P G ++ L + G +R Sbjct: 5469 CPRALSIHYKS-MDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDI 5527 Query: 256 SAFTLAWDGASAVYIKMSPELL--GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSW 313 A ++ V+ P L T G CG + +DD + G + +W Sbjct: 5528 PALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTW 5587 Query: 314 -------------QEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGVYEQCEALLRPPFDA 359 P P SS P P PC Q C+ +L F Sbjct: 5588 LVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ---------PLCDLMLSQVFAE 5638 Query: 360 CHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQL-RQCTVH 418 CH V P PF +C SD C+ G + C++L YA C G WR C + Sbjct: 5639 CHNLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLT 5695 Query: 419 CKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP-NGLIFEDGGCVAPAECPCEF 477 C Y C PA+C+ R E +GC+CP + ++F + CPC Sbjct: 5696 CPPTK-VYKPCGPIQPATCNSRNQSPQLE-GMAEGCFCPEDQILFNAHMGICVQACPCVG 5753 Query: 478 -HGTLYPPGSVVKEDCNTCTCTSG--KWECSTAVCPAE 512 G PG +C +C C G +C C A+ Sbjct: 5754 PDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQ 5791 Score = 91.3 bits (225), Expect = 1e-17 Identities = 137/521 (26%), Positives = 192/521 (36%), Gaps = 74/521 (14%) Query: 1479 TLPPSQGLPTPSD-----EEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVS 1533 T PP + L +P+ S SPRT T P LT A +TA + T P + Sbjct: 4748 TAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTA----TSVTPIPSST 4803 Query: 1534 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1593 G T T +Q A+ P+ +P + T+++L T ++ + + TPG Sbjct: 4804 LGTTGTLPEQTTTPVATMSTIHPSSTPETTH-TSTVLTTKATTTRATSSTSTPSSTPGTT 4862 Query: 1594 SGAME-TTRVTVIFAGSPNITVSSRSPPAPRF---PLMTKAVTVRGHGSLPVRTTPP--- 1646 E TT T A P T S S P + L T A T GS ++ P Sbjct: 4863 WILTELTTAATTTAATGPTATPS--STPGTTWILTELTTTATTTASTGSTATPSSTPGTT 4920 Query: 1647 ----QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS 1702 +PS TA+ + P S S + ++G+ T V S P + + + Sbjct: 4921 WILTEPSTTATVTV-PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATA 4979 Query: 1703 SP---STPLTVAGTAAEQVPVSPLATRSLEI-VLSTEKGEAGHSQPMGSPASPQPHPLPS 1758 P ST T T+ +P S L T + +T + P +P + + + Sbjct: 4980 LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLT 5039 Query: 1759 APPRPAQHTTMATRSPALPPETPAAASL----STATDGLAATPFMSLESTRPSQLLSGLP 1814 A TT AT S A P TP A +T T G ATP S Sbjct: 5040 A----TATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSS-------------- 5081 Query: 1815 PDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPT 1874 P T+L + P TP S I T P+ T S VL T A MT+A T Sbjct: 5082 PGTAL-------TPPTTTPMSTMSTIHTSSTPETT-----HTSTVLT-TTATMTRATNST 5128 Query: 1875 HIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSM 1934 P LG T + + A TA+ S ST G IL++ ++ T M Sbjct: 5129 --------ATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVM 5180 Query: 1935 YGSAEGGPTELTPATSHPLTPLVAEPEGAQ-AGTALPVPTS 1974 + T T+H TP V TA VP+S Sbjct: 5181 VPTGSTATASSTLGTAH--TPKVVTTMATMPTATASTVPSS 5219 Score = 84.7 bits (208), Expect = 1e-15 Identities = 95/386 (24%), Positives = 147/386 (38%), Gaps = 60/386 (15%) Query: 2554 CRQDQILITGRLGDSCCTSYFCACGDCPDSIPE------CQEGEALTVHRNTTELCCPLY 2607 C +DQIL +G C C C PD P+ ++ + + C Sbjct: 5731 CPEDQILFNAHMG--ICVQA-CPCVG-PDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPL 5786 Query: 2608 QCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIP--VPRCHLWEKSQLDEE 2665 C + P + G T + + + CCP C C+ T P +P C ++S +E Sbjct: 5787 PCDAQGQPPPCNRPGFVT-VTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQE 5845 Query: 2666 FMHSVENVCGCAKYECVKAPVCLSR----ELGVMQPGQTVVELSADGVCHTSRCTT--VL 2719 E C C + C + +C +G PG CH C + Sbjct: 5846 -----EGDC-CPTFRC-RPQLCSYNGTFYGVGATFPGAL--------PCHMCTCLSGDTQ 5890 Query: 2720 DPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGA 2779 DP + + C Q +E+ R CCG C +CL P+G Sbjct: 5891 DPTVQCQEDACNNTTCP------QGFEYKRVAGQCCGECVQTACL--TPDGQPVQL--NE 5940 Query: 2780 SW----IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKED 2835 +W + +C + C + +L P SCP ++ GS+ + GCC +C+ED Sbjct: 5941 TWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCR-----GSLRKT--GCCYSCEED 5993 Query: 2836 GRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQR 2895 SC +V I TI ++ T VN+ C+G CP AS Y+ C CC+E + Sbjct: 5994 --SC-QVRINTTILWHQ-GCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHE 6049 Query: 2896 RSVQLFCATNATWVPYTVQEPTDCAC 2921 +V L C N + + +T C Sbjct: 6050 ETVPLHC-PNGSAILHTYTHAVQVLC 6074 Score = 83.2 bits (204), Expect = 3e-15 Identities = 133/580 (22%), Positives = 205/580 (35%), Gaps = 65/580 (11%) Query: 1501 PRTP-THRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTES 1559 P TP T A+ + P TT + +T T S G T T P ++ P + Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT 4761 Query: 1560 PASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGS-PNITVSSRS 1618 P + A+ + P T +++LPV T T + T+ G+ P T + + Sbjct: 4762 PTATSSKATSSSSPRT--ATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVA 4819 Query: 1619 PPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRP----------VASPGAISRS 1668 + P T T TT S T++PSS P A+ + Sbjct: 4820 TMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATG 4879 Query: 1669 PTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSL 1728 PT++ S TP T +++ T A S S +TP + GT + P T ++ Sbjct: 4880 PTATPSS----TPGTTWILTELTTTATTTA-STGSTATPSSTPGTT--WILTEPSTTATV 4932 Query: 1729 EIVLSTEKGEAGHSQPMGSPASPQPHPLP---SAPPRPAQHTTMATRSPAL--PPETPAA 1783 + + + G+P P S+ P+ AT PAL TP A Sbjct: 4933 TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTA 4992 Query: 1784 ASLSTATDGLAATPFMSL-ESTRPSQLLSGLPPDTSLPLAKVGT--SAPVATPGPKASVI 1840 S + T + L ++T P+ +S P ++ T +A T G SV Sbjct: 4993 TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVA 5052 Query: 1841 T---TPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAA---GTAPGLLLGATLP 1894 T TP T +P T + FT A + P T + PP T + +T Sbjct: 5053 TPSSTPGTAHTTKVPTTTTTG---FT--ATPSSSPGTALTPPTTTPMSTMSTIHTSSTPE 5107 Query: 1895 TSGVLPVAEGTASMV----SVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATS 1950 T+ V TA+M S ST G IL++ + T+ + TP T+ Sbjct: 5108 TTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTT 5167 Query: 1951 HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLA 2010 LT EP S ++ P S L AH +A Sbjct: 5168 WILT----EP-----------------STIATVMVPTGSTATASSTLGTAHTPKVVTTMA 5206 Query: 2011 AEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTT 2050 P A+T PS + L +L T + + S++ Sbjct: 5207 TMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSS 5246 Score = 80.9 bits (198), Expect = 2e-14 Identities = 136/523 (26%), Positives = 192/523 (36%), Gaps = 84/523 (16%) Query: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGS-------------PNITVSSRSP 1619 P TP +SS + TP + + TT T GS P + S + Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT 4761 Query: 1620 PAPRFPLMTKAVTVRGHGSLPVRTT----PPQPSLTASPSS-------------RPVASP 1662 P T + + R +LPV T+ S+T PSS PVA+ Sbjct: 4762 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATM 4821 Query: 1663 GAISRSPTSSGSH-KAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAG--TAAEQVP 1719 I S T +H VLT T + + P+ + T LT A TAA Sbjct: 4822 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4881 Query: 1720 VSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPE 1779 +P +T +L+ A + GS A+P P + +T AT +P Sbjct: 4882 ATPSSTPGTTWILTELTTTATTTASTGSTATPS--STPGTTWILTEPSTTAT--VTVPTG 4937 Query: 1780 TPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPD------TSLPLAKVGTSAPVATP 1833 + A AS + AT A TP +S +T P+ S P T+LP + + P AT Sbjct: 4938 STATASSTQAT---AGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS 4994 Query: 1834 G---PKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1890 P +S+ TT + TT P T+S P + T T A T G Sbjct: 4995 FTAIPSSSLGTTWTRLSQTTTPTATMSTATP----SSTPETVHTSTVLTATATTTGATGS 5050 Query: 1891 ATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATS 1950 P+S GTA + VP +TTG A P+S G+A PT TP ++ Sbjct: 5051 VATPSS-----TPGTAH-TTKVPTTTTTGFTA-------TPSSSPGTALTPPT-TTPMST 5096 Query: 1951 HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLA 2010 + PE T L T+ ++R + TA S L GT+ + Sbjct: 5097 MSTIHTSSTPETTHTSTVL--TTTATMTRATNSTATPSSTL----------GTT---RIL 5141 Query: 2011 AEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 E ATT + S LS G L T + +T VP Sbjct: 5142 TELTTTATTTAATGSTATLSSTPGTTWIL--TEPSTIATVMVP 5182 Score = 79.3 bits (194), Expect = 5e-14 Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%) Query: 2179 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2238 V I V V+ PV P S+ G I+ + + + + W H L++ +K Sbjct: 143 VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202 Query: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298 + + GLCG +G L + + P F + ++ P Sbjct: 203 YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257 Query: 2299 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2352 +T C ++ + FS C V S+ E + DT + C L Y Sbjct: 258 NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317 Query: 2353 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2411 C H + +WR D+CP C ++ Y C + C TC + +HC GC Sbjct: 318 CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372 Query: 2412 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2456 C EGT+L C+P +KCAC + G A G T+++ + C Sbjct: 373 FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416 Score = 79.0 bits (193), Expect = 7e-14 Identities = 71/280 (25%), Positives = 120/280 (42%), Gaps = 44/280 (15%) Query: 985 CTAYGDRHYRTFDGLPFDFVGACKV-------------HLVKSTSDVSFSVIVENVNCYS 1031 C+ +G HY+TFDG F F G C ++ S S + + V Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKV 140 Query: 1032 SGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1091 G++ I + G+ L+ +G+P F + V + +T V + + L+ Sbjct: 141 DGVV----IQLTKGSVLV-----NGHPVLLPF--SQSGVLIQQSSSYTKVE-ARLGLVLM 188 Query: 1092 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1151 W+ ++ ++ ++ + GLCG+F+ + N +LT P EFG+ ++ D Sbjct: 189 WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT-PMEFGN----LQKMD- 242 Query: 1152 LDPRDMCVLNPLREPFAKKECS--------ILLSEVFEICHPVVDVTWFYSNCLTDTCGC 1203 DP + C +P+ EP + CS +L ++F C +VDV + C D C C Sbjct: 243 -DPTEQCQ-DPVPEP--PRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFC 298 Query: 1204 SQGGDCECFCASVSAYAHQCCQ-HGVAVDWRTPRLCPYDC 1242 C C +++ Y+ QC G+ DWR P CP C Sbjct: 299 EDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKC 338 Score = 75.1 bits (183), Expect = 9e-13 Identities = 115/455 (25%), Positives = 168/455 (36%), Gaps = 80/455 (17%) Query: 1470 VPTEALGNE-TLPPSQGLP--TPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1526 +P+ LG TLP P T S P + E+ T T LT A T A + T Sbjct: 3652 IPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTST---VLTTKATTTRATSSMST- 3707 Query: 1527 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1586 P +PG T + T + GPT +P+S T +L P T + ++P Sbjct: 3708 ---PSSTPGTTWILTELTTAATTTAA-TGPTATPSSTPGTTWILTEPSTTATVTVPTG-S 3762 Query: 1587 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT--- 1643 T T T +V A +P + +SSR+ P+ T +R + P T Sbjct: 3763 TATASSTRATAGTLKVLTSTATTPTV-ISSRATPSSSPGTATALPALRSTATTPTATSVT 3821 Query: 1644 ------------------TPPQPSLTASPSSRP--VASPGAISRSPTSSGSHKAVLTPAV 1683 TP TA+PSS P V + ++ + T++ + +V TP+ Sbjct: 3822 AIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSS 3881 Query: 1684 TKVISRTG-VPQPTQ----AQSASSPSTPLT----VAGTAAEQV------PVSPLATRSL 1728 T + T VP T A +SSP T LT ++ T P S T Sbjct: 3882 TPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHT 3941 Query: 1729 EIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETP--AAASL 1786 VL+T +S Q PP P +TT T +LPP +P + Sbjct: 3942 ATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVP--NTTATTHGRSLPPSSPHTVRTAW 3999 Query: 1787 STATDGLAATPFMS-----------------------LESTRPSQLLSGLPPD--TSLPL 1821 ++AT G+ T ++ L S PS + PP T+ P Sbjct: 4000 TSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 4059 Query: 1822 AKVGTSAPVATPGPKASVITTPLQPQATTLPAQTL 1856 GTS AT P + +T L T+ P T+ Sbjct: 4060 HTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTV 4094 Score = 73.9 bits (180), Expect = 2e-12 Identities = 104/444 (23%), Positives = 158/444 (35%), Gaps = 89/444 (20%) Query: 2091 GLAVRVGGDRCC---PLWECACR-----CSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2142 G +RV + C WEC+ R C + D F+TFDG + YIL+Q Sbjct: 1526 GETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYC 1585 Query: 2143 EMLTVH-VLDCKSANLGHLNWPPFCLVMLNM---THLAHQVTI------DRFNRKVTVDL 2192 T H + N+ C + + A V+ + R+ +V Sbjct: 1586 GDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGF 1645 Query: 2193 QPVWPPVSRYGFRIEDTGH-------------------MYMILTPSDIQIQWLHSSGLMI 2233 + PP+ Y +++ +++++ + + W + + I Sbjct: 1646 RQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFI 1705 Query: 2234 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSV 2289 + K + GLCG D +A ND + SVVG D F +SW++ P +L Sbjct: 1706 -RLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVG---DALEFGNSWKLSPSCPDALAPK 1761 Query: 2290 GQTRFRP--DSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----- 2342 P S A CS ++ TF+AC V + E + D Sbjct: 1762 DPCTANPFRKSWAQKQCS----ILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCEC 1817 Query: 2343 -CVALTVYVAMCHKFHVCIEWRRSDYCPFLC-------SSDSTYQACVTACEPPKTCQDG 2394 C A+ Y CH +C+ WR D CP C + YQ C C KTC++ Sbjct: 1818 FCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPC--LKTCRN- 1874 Query: 2395 ILGPLDPEHCQV---LGEGCV--CSEGTILHRRHSALCIPEAKCACTDSMG--------V 2441 HC V EGC C C+ A+C C D G V Sbjct: 1875 -----PSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGNYYDVGARV 1927 Query: 2442 PRALG-ETWNSSLSGC-CQHQCQA 2463 P A ++ N + SG C H +A Sbjct: 1928 PTAENCQSCNCTPSGIQCAHSLEA 1951 Score = 70.9 bits (172), Expect = 2e-11 Identities = 137/593 (23%), Positives = 211/593 (35%), Gaps = 75/593 (12%) Query: 1503 TPTHRPALTPAAPLTTALNPPVTATE-EPVVSPGPTQTTLQQPLELTASQLPAGPTESP- 1560 T T R A P TTA P VT+++ P SPG T T L P + + P + +P Sbjct: 2620 TSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPG-TATAL--PALRSTATTPTATSVTPI 2676 Query: 1561 --ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRS 1618 +S G T + L+ TP ++ + T TP T+ V A + T S + Sbjct: 2677 PSSSLGTTWTRLSQTTTPTAT-----MSTATPSSTPETAHTSTVLTATATTTGATGSVAT 2731 Query: 1619 PPA-PRFPLMTKAVTVRGHGSLPVRTTPPQPSLT----ASPSSRPVASPGAISRSPTSSG 1673 P + P TK T G ++ P +LT S ++ P ++ S Sbjct: 2732 PSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGT 2791 Query: 1674 SHKAVLTPAVTKVISRTGVPQPTQAQSAS----SPSTPLTVAGTAAEQVPVSPLATRSLE 1729 +H A + T ++ + P+ + S +P P T+A T +P P + ++ Sbjct: 2792 THTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLP--PSSPHTVR 2849 Query: 1730 IVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA----------TRSPALPPE 1779 ++ + + P++ H L +A QH+T A T SP P Sbjct: 2850 TAWTSATSGILGTTHITEPSTVTSHTL-AATTGTTQHSTPALSSPHPSSRTTESPPSPGT 2908 Query: 1780 TPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASV 1839 T + +T+ ATP TR S LL P TSAP+ T V Sbjct: 2909 TTPGHTTATSRTTATATP----SKTRTSTLLPSSP-----------TSAPITT------V 2947 Query: 1840 ITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAP-GLLLGAT----LP 1894 +T +PQ S +P + A A P GL A +P Sbjct: 2948 VTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVP 3007 Query: 1895 TSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVSLPTSMYGSAEGGPT-------ELT 1946 + V E + V + GK + + ++ + YG P T Sbjct: 3008 LRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSST 3067 Query: 1947 PATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAG 2006 P T+ LT L ++ + P+S T P + V +P + A +S Sbjct: 3068 PGTTWILTELTTTATTTESTGSTATPSS-TPGTTWILTEPSTTATVTVPTGSTATASSTQ 3126 Query: 2007 PHLAAEPVDEATTEPSGRSAPALSIVE-GLAEAL-----ATTTEANTSTTCVP 2053 V T P+ S+ A G A AL TT TS T +P Sbjct: 3127 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIP 3179 Score = 69.3 bits (168), Expect = 5e-11 Identities = 105/439 (23%), Positives = 159/439 (36%), Gaps = 58/439 (13%) Query: 1501 PRTPTHRPALTPAA-PLTTALNPPVTATEEPVVSPGPTQTT---------LQQPLELTAS 1550 P TP TP++ P TT + +T T S G T T L +P Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 4259 Query: 1551 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSP 1610 +P G T + +S TA PH +++ P + S T P Sbjct: 4260 TVPTGSTATASSTQATA---GTPHVSTTATTPTVTSSKATPFSSPGTAT--------ALP 4308 Query: 1611 NITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRP--VASPGAISRS 1668 + ++ +P A F + + L TTP TA+PSS P + ++ + Sbjct: 4309 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 4368 Query: 1669 PTSSGSHKAVLTPAVTK-VISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRS 1727 T++ + +V TP+ T T VP T +PS+ SP R+ Sbjct: 4369 ATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSS--------------SPGTART 4414 Query: 1728 LEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLS 1787 + +ST + P S ++ P +P P T + T + + + A S S Sbjct: 4415 PPVWISTT------TTPTTSGSTVTPSSVPGTTHTP---TVLTTTTTTVATGSMATPSSS 4465 Query: 1788 TATDGLAAT-PFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQP 1846 T T G T P + +T + LS P T TS + T T P Sbjct: 4466 TQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTP 4525 Query: 1847 QATTLPAQTLSPVL--PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLP----TSGVLP 1900 ATT Q +P L P + T++ P P TA P TS +LP Sbjct: 4526 AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLP 4585 Query: 1901 VAEGTASMVSVVPRKSTTG 1919 + +A + +VV TTG Sbjct: 4586 SSPTSAPITTVV----TTG 4600 Score = 68.9 bits (167), Expect = 7e-11 Identities = 157/651 (24%), Positives = 232/651 (35%), Gaps = 124/651 (19%) Query: 1479 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1538 T PP+ L T + Q +P+ PT P LT A PP + T P +S G T Sbjct: 2302 TPPPTTELETATTTTTQALFSTPQ-PTSSPGLTRA--------PPASTTAVPTLSEGLTS 2352 Query: 1539 TTLQQPLELTAS---QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSG 1595 L + PAG TE P GV S L P S+LP +G Sbjct: 2353 PRYTSTLGTATTGGPTTPAGSTE-PTVPGVATSTL-----PTRSALPGT---------TG 2397 Query: 1596 AMETTRVTVIFAGSPNITVSSRSPP------APRFPLMTK-AVTVRGHGSLP-VRTTPPQ 1647 ++ T R + +P +SR+ P A + PL T A T+ S T+ P+ Sbjct: 2398 SLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPR 2457 Query: 1648 PSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVP-------QPTQAQS 1700 T SP + S G P K T +GV + +A Sbjct: 2458 TETTMSPLTNTTTSQGTTRCQP------KCEWTEWFDVDFPTSGVAGGDMETFENIRAAG 2511 Query: 1701 ASSPSTPLTVAGTAAEQVP------VSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH 1754 P ++ AE P V + T SLE L+ + + M + + Sbjct: 2512 GKMCWAPKSIE-CRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVL 2570 Query: 1755 PLPSAPPRPAQHTTMATRSPALPPET------PAAASLSTATDGLAATPFMSLESTRPSQ 1808 P+ T +T +P+ P T P + +TA+ G ATP +L + P + Sbjct: 2571 CCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPK 2630 Query: 1809 LL-----------------SGLPPDTSLPLAKVGTSAPVA---TPGPKASVITTPLQPQA 1848 +L S T+LP + + P A TP P +S+ TT + Sbjct: 2631 VLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQ 2690 Query: 1849 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASM 1908 TT P T+S P + AH T + A T G P+S GTA Sbjct: 2691 TTTPTATMSTATP--SSTPETAHTSTVLT--ATATTTGATGSVATPSS-----TPGTAH- 2740 Query: 1909 VSVVPRKSTTGKVAILSKQ--VSLPTSMYGSAEGGPT--------ELTPATSHPLTPLVA 1958 + VP +TTG A S +L ++ S PT P T+H T L Sbjct: 2741 TTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT 2800 Query: 1959 EPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTS---AGPHLAAEPVD 2015 G ++ P+S + + T P + +A HG S + PH Sbjct: 2801 TTTTVATG-SMATPSSSTQTSGTTHTPPVPN------TMATTHGRSLPPSSPHTVRTAWT 2853 Query: 2016 EAT---------TEPSGRSAPALSIVEGLAE----ALATTTEANTSTTCVP 2053 AT TEPS ++ L+ G + AL++ ++ +T P Sbjct: 2854 SATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPP 2904 Score = 68.9 bits (167), Expect = 7e-11 Identities = 79/314 (25%), Positives = 115/314 (36%), Gaps = 52/314 (16%) Query: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIV 1024 CV RG + P A C+ +G HY TFDG + F G C L++ + S+ + Sbjct: 5397 CVGGRG-----ITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYL 5451 Query: 1025 ENVNCYSSGMI------CRKFISINVGN---------------SLIVFDDDSGNPSPESF 1063 +N C +S C + +SI+ + LI+FD P S Sbjct: 5452 DNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQ-----IPVSS 5506 Query: 1064 LDDKQEVHTWRVGFFTL-VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF----- 1117 K V +G T+ V P +++ ++ + + G CG Sbjct: 5507 GFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQR 5566 Query: 1118 ------DLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKE 1171 D T + L WA P T P P P + Sbjct: 5567 DDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQP 5626 Query: 1172 -CSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV 1230 C ++LS+VF CH +V F++ C++D C G E C S+ AYA C GV Sbjct: 5627 LCDLMLSQVFAECHNLVPPGPFFNACISDHC----RGRLEVPCQSLEAYAELCRARGVCS 5682 Query: 1231 DWR--TPRLCPYDC 1242 DWR T LC C Sbjct: 5683 DWRGATGGLCDLTC 5696 Score = 67.8 bits (164), Expect = 2e-10 Identities = 84/375 (22%), Positives = 135/375 (36%), Gaps = 36/375 (9%) Query: 2111 CSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVML 2170 CS + D + TFDG Y+ S+ + + +G V+ Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP------VVT 786 Query: 2171 NMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSG 2230 + A + ++ N V ++ Q P SR G +E +G + + W + Sbjct: 787 RVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLW-NGED 845 Query: 2231 LMIVEASKTSKAQGHGLCGICDG-DAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2289 ++E Q GLCG +G A N+ + + P F + ++ Sbjct: 846 SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLT-----PLQFGNLQKLDGPTEQC 900 Query: 2290 GQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-KYVQQPCVALTV 2348 P T + C R + F+ CH V ++ +D + PC Sbjct: 901 PDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATFVE 960 Query: 2349 YVAMC-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVL 2407 Y C H WR + CP C + +Q C + C TC + L +HC Sbjct: 961 YSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPC--TDTCSNPQRAQLCEDHCV-- 1016 Query: 2408 GEGCVCSEG---TILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC-CQ---HQ 2460 +GC C G T+L + C+P +C CT G + G ++N++ S C C Q Sbjct: 1017 -DGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG-GRTYSPGTSFNTTCSSCTCSGGLWQ 1074 Query: 2461 CQAPDTIVPVDLGCP 2475 CQ DL CP Sbjct: 1075 CQ--------DLPCP 1081 Score = 67.8 bits (164), Expect = 2e-10 Identities = 114/436 (26%), Positives = 152/436 (34%), Gaps = 95/436 (21%) Query: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632 P TP +SS TP + TT T GS S+ Sbjct: 2579 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTST---------------- 2622 Query: 1633 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692 +RT PP LT + ++ V S S++ SS A PA+ R+ Sbjct: 2623 --------LRTAPPPKVLTTTATTPTVTS----SKATPSSSPGTATALPAL-----RSTA 2665 Query: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1752 PT PS+ L T Q +P AT S ST E H+ + + + Sbjct: 2666 TTPTATSVTPIPSSSLGTTWTRLSQT-TTPTATMSTATPSSTP--ETAHTSTVLTATAT- 2721 Query: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASL----STATDGLAATPFMSLESTRPSQ 1808 TT AT S A P TP A +T T G ATP S+ P Sbjct: 2722 --------------TTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATP-----SSSPGT 2762 Query: 1809 LLSGLPP----DTSLPLAKVGTSAPVATPGP--KASVITTPLQPQATTLPAQTLSPVLPF 1862 L+ PP T+ P + T P + PG A+V+TT AT A Sbjct: 2763 ALT--PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMA--------- 2811 Query: 1863 TPAAMTQAHPPTHI--APPAAGTAPGLLLGATLP----------TSGVLPVAEGT-ASMV 1909 TP++ TQ TH P T G L + P TSG+L T S V Sbjct: 2812 TPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTV 2871 Query: 1910 SVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPL----TPLVAEPEGAQA 1965 + +TTG + +S P + E P+ T H T A P + Sbjct: 2872 TSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRT 2931 Query: 1966 GTALP-VPTSYALSRV 1980 T LP PTS ++ V Sbjct: 2932 STLLPSSPTSAPITTV 2947 Score = 67.0 bits (162), Expect = 3e-10 Identities = 115/507 (22%), Positives = 168/507 (33%), Gaps = 46/507 (9%) Query: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632 P TP +SS TP + T T GS I S+ P L + A T Sbjct: 3555 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3614 Query: 1633 -------VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVT- 1684 S TT P + TA+ S+ +P T+ + TP T Sbjct: 3615 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3674 Query: 1685 KVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQP 1744 I + P+ T + + T A T++ P S T + L+T + P Sbjct: 3675 STIHPSSTPETTHTSTVLTTKATTTRA-TSSMSTPSSTPGTTWILTELTTAATTTAATGP 3733 Query: 1745 MGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLEST 1804 +P+S P T+ T S A T A A A TP + Sbjct: 3734 TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRA 3793 Query: 1805 RPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTP 1864 PS S T+LP + + P AT + I + A T +QT +P + Sbjct: 3794 TPS---SSPGTATALPALRSTATTPTAT---SVTAIPSSSLGTAWTRLSQTTTPTATMST 3847 Query: 1865 AAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAIL 1924 A + H + T ++ T P GTA + VP +TTG A Sbjct: 3848 ATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTP---GTAH-TTKVPTTTTTGFTA-- 3901 Query: 1925 SKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSART 1984 P+S G+A P ++ T+ P +++P T A + T Sbjct: 3902 -----TPSSSPGTALTPPVWISTTTTPTTRGSTVTP------SSIPGTTHTATVLTTTTT 3950 Query: 1985 APQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALS-------IVEGLAE 2037 + + GT+ P PV T GRS P S + Sbjct: 3951 TVATGSMATPSSSTQTSGTTHTP-----PVPNTTATTHGRSLPPSSPHTVRTAWTSATSG 4005 Query: 2038 ALATT--TEANTSTTCVPIAEQDCVRH 2062 L TT TE +T T+ P A +H Sbjct: 4006 ILGTTHITEPSTVTSHTPAATTSTTQH 4032 Score = 66.2 bits (160), Expect = 4e-10 Identities = 140/612 (22%), Positives = 207/612 (33%), Gaps = 86/612 (14%) Query: 1469 WVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATE 1528 W+ TE T+ +PT S +Q + TP TTA P VT+++ Sbjct: 4248 WILTEPSTTATVT----VPTGSTATASSTQATAGTPHVS---------TTATTPTVTSSK 4294 Query: 1529 -EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASK-GVTASLLAIPHTPESS-SLPVAL 1585 P SPG T T L + T P+S G T + L+ TP ++ S Sbjct: 4295 ATPFSSPG-TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS 4353 Query: 1586 QTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT-- 1643 TP S + TT T GS + S P T G P + Sbjct: 4354 STPETAHTSTVLTTTATTTRATGS---VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPG 4410 Query: 1644 TPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS- 1702 T P + S ++ P S ++ S +H + T ++ + P+ + S Sbjct: 4411 TARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG 4470 Query: 1703 ---SPSTPLTVAGTAAEQV-PVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPS 1758 +P P T A T + P SP R+ S G G + + P++ H P+ Sbjct: 4471 TTHTPPVPNTTATTHGRSLSPSSPHTVRT--AWTSATSGTLGTTH-ITEPSTGTSH-TPA 4526 Query: 1759 APPRPAQHTTMA----------TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQ 1808 A QH+T A T SP P T + +T+ ATP TR S Sbjct: 4527 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATP----SKTRTST 4582 Query: 1809 LLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMT 1868 LL P TSAP+ T V+TT +PQ S +P Sbjct: 4583 LLPSSP-----------TSAPITT------VVTTGCEPQCAWSEWLDYSYPMPGPSGGDF 4625 Query: 1869 QAHPPTHIAPPAAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI 1923 + A A P GL A +P + V E + V + GK + Sbjct: 4626 DTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKM 4685 Query: 1924 -LSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSA 1982 + ++ + YG TPATS P + P T L + S S Sbjct: 4686 CFNYEIRVFCCNYGHCPS-----TPATSSTAMP-SSTPGTTWILTELTTTATTTASTGST 4739 Query: 1983 RTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATT 2042 T + GT+ P + P T S ++ + L +T Sbjct: 4740 ATP------------SSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTST 4787 Query: 2043 TEANTSTTCVPI 2054 +T+T+ PI Sbjct: 4788 ATKSTATSVTPI 4799 Score = 65.1 bits (157), Expect = 1e-09 Identities = 144/620 (23%), Positives = 218/620 (35%), Gaps = 102/620 (16%) Query: 1469 WVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATE 1528 W+ TE T+ +PT S +Q + TP TTA P VT+++ Sbjct: 3101 WILTEPSTTATVT----VPTGSTATASSTQATAGTPHVS---------TTATTPTVTSSK 3147 Query: 1529 -EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASK-GVTASLLAIPHTPESSSLPVALQ 1586 P SPG T T L + T P+S G T + L+ TP ++ + Sbjct: 3148 ATPFSSPG-TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTAT-----MS 3201 Query: 1587 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPA-PRFPLMTKAVTVRGHGSLPVRTTP 1645 T TP + T+ V A + T S +P + P TK +T G ++ Sbjct: 3202 TATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSS 3261 Query: 1646 PQPSLT----ASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSA 1701 P + T S ++ P ++ S +H + T ++ + P+ + Sbjct: 3262 PGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQT 3321 Query: 1702 S----SPSTPLTVAGTAAEQV-PVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPL 1756 S +P P T A T + P SP R+ S G G + + P++ H Sbjct: 3322 SGTTHTPPVPNTTATTHGRSLSPSSPHTVRT--AWTSATSGTLGTTH-ITEPSTGTSH-T 3377 Query: 1757 PSAPPRPAQHTTMA----------TRSPALPPETPAAASLSTATDGLAATPFMSLESTRP 1806 P+A QH+T A T SP P T + +T+ ATP TR Sbjct: 3378 PAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATP----SKTRT 3433 Query: 1807 SQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAA 1866 S LL P TSAP+ T V+T +PQ S +P Sbjct: 3434 STLLPSSP-----------TSAPITT------VVTMGCEPQCAWSEWLDYSYPMPGPSGG 3476 Query: 1867 MTQAHPPTHIAPPAAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKV 1921 + A A P GL A +P + V E + V + GK Sbjct: 3477 DFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKF 3536 Query: 1922 AI-LSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAE------PEGAQAGTALPVPTS 1974 + + ++ + YG TPATS TP E A T S Sbjct: 3537 KMCFNYEIRVFCCNYGHCPS-----TPATSSTATPSSTPGTTWILTEQTTAATTTATTGS 3591 Query: 1975 YALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEG 2034 A+ + TAP +L T+ P + +AT+ S R+A L + Sbjct: 3592 TAIPSSTPGTAPPPKVLT---------STATTPTATS---SKATSSSSPRTATTLPV--- 3636 Query: 2035 LAEALATTTEANTSTTCVPI 2054 L +T +T+T+ PI Sbjct: 3637 ----LTSTATKSTATSFTPI 3652 Score = 64.3 bits (155), Expect = 2e-09 Identities = 76/301 (25%), Positives = 117/301 (38%), Gaps = 20/301 (6%) Query: 1500 SPRTPTHRPALTPAAPL--TTALNPPVTA-TEEPVVSPGPTQTTLQQPLELTASQLPAGP 1556 S TP+ P A P +TA P T+ T P S G T T L Q TA+ A P Sbjct: 4966 SKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATP 5025 Query: 1557 TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS 1616 + +P + T+++L T ++ VA + TPG T T F +P+ + + Sbjct: 5026 SSTPETVH-TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGT 5084 Query: 1617 RSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHK 1676 P P+ T + H S TT LT + + + A +P+S+ Sbjct: 5085 ALTPPTTTPMSTMSTI---HTSSTPETTHTSTVLTTTATMTRATNSTA---TPSSTLGTT 5138 Query: 1677 AVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAE-QVPVSPLATRSLEIVLSTE 1735 +LT T + S + LT T A VP AT S + Sbjct: 5139 RILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTL----- 5193 Query: 1736 KGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAA 1795 G A + + + A+ P +A P+ T TR+PA+ P + S+ST + + Sbjct: 5194 -GTAHTPKVVTTMATM---PTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLT 5249 Query: 1796 T 1796 T Sbjct: 5250 T 5250 Score = 62.8 bits (151), Expect = 5e-09 Identities = 138/642 (21%), Positives = 203/642 (31%), Gaps = 106/642 (16%) Query: 1500 SPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTES 1559 SP T T PAL A TA + T P S G T L Q TA+ A P+ + Sbjct: 3798 SPGTATALPALRSTATTPTA----TSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSST 3853 Query: 1560 PASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPN-------- 1611 P + T+++L T ++ VA + TPG T T F +P+ Sbjct: 3854 PETVH-TSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALT 3912 Query: 1612 --ITVSSRSPPAPR---------------FPLMTKAVTVRGHGSLPVRT----------T 1644 + +S+ + P R ++T T GS+ + T Sbjct: 3913 PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHT 3972 Query: 1645 PPQPSLTASPSSR--PVASPGAISRSPTSSGSHKAVL--------------TPAVTKVIS 1688 PP P+ TA+ R P +SP + + TS+ S +L TPA T + Sbjct: 3973 PPVPNTTATTHGRSLPPSSPHTVRTAWTSATS--GILGTTHITEPSTVTSHTPAATTSTT 4030 Query: 1689 RTGVP-----QPTQAQSASSPS----TPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEA 1739 + P P+ + S PS TP GT+ +P TR+ +L + A Sbjct: 4031 QHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRT-STLLPSSPTSA 4089 Query: 1740 GHSQPMGSPASPQ---------PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTAT 1790 + + + PQ +P+P P T + A L Sbjct: 4090 PITTVVTTGCEPQCAWSEWLDYSYPMPG--PSGGDFDTYSNIRAAGGAVCEQPLGLECRA 4147 Query: 1791 DGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPV-----------ATPGPKASV 1839 P L L GL + K P S Sbjct: 4148 QAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSS 4207 Query: 1840 ITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVL 1899 TP TT L+ T + + A P + T P T+PT Sbjct: 4208 TATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTA 4267 Query: 1900 PVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAE 1959 + A+ + P STT ++ + P S G+A P + AT+ T A Sbjct: 4268 TASSTQAT--AGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAI 4325 Query: 1960 PEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATT 2019 P + T +R+S T P +M P T H + ATT Sbjct: 4326 PSSSLGTT---------WTRLSQTTTPTATMSTATPS-----STPETAHTSTVLTTTATT 4371 Query: 2020 EPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQDCVR 2061 + S S G A T T T P + R Sbjct: 4372 TRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTAR 4413 Score = 61.2 bits (147), Expect = 1e-08 Identities = 63/260 (24%), Positives = 104/260 (40%), Gaps = 22/260 (8%) Query: 2232 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2291 + V + Q GLCG + + A+D T G V A F ++W+ ++ + Sbjct: 1205 VFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATG---AAFANTWKAQAACANARN 1261 Query: 2292 TRFRPDSCATTDCSP----CLRMVS-NRTFSACHRFVPPESFCELWIRDTKYVQQP---- 2342 + P S + + + C R+ N FS CH + P+ F + DT ++ Sbjct: 1262 SFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCL 1321 Query: 2343 CVALTVYVAMCHKFHVCI-EWRRSDYCPFL--CSSDSTYQACVTACEPPKTCQDGILGPL 2399 C AL+ YV C V + +WR ++ C Y V AC+P TC+ + Sbjct: 1322 CAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQP--TCRGLSEADV 1379 Query: 2400 DPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWN--SSLSGCC 2457 V +GC C GT L+ + C+P +C C + G A GE + ++ C Sbjct: 1380 TCSVSFVPVDGCTCPAGTFLN--DAGACVPAQECPCY-AHGTVLAPGEVVHDEGAVCSCT 1436 Query: 2458 QHQCQAPDTIVPVDLGCPSP 2477 + + GC +P Sbjct: 1437 GGKLSCLGASLQKSTGCAAP 1456 Score = 53.5 bits (127), Expect = 3e-06 Identities = 80/355 (22%), Positives = 116/355 (32%), Gaps = 53/355 (14%) Query: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQ-VLDEVTQRCVYLEDCVEP 1466 CEW Y C +PC +TCR+P D+P C P CP Q +E +CV C + Sbjct: 1857 CEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDK 1916 Query: 1467 -------AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP-----AA 1514 VPT G+ E RT +++ + A Sbjct: 1917 DGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGA 1976 Query: 1515 PLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1574 L T + V PG TT P T + +P S S + S + + Sbjct: 1977 CLIAICGSNGTIIRKAVACPGTPATT---PFTFTTAWVP----HSTTSPALPVSTVCVRE 2029 Query: 1575 TPESSSLPVALQTPTPGMVSGAMET--------TRVTVIFAGSPNITVSSRSPPAPRFPL 1626 SS P PG+ G ET +V + A + R+ P PL Sbjct: 2030 VCRWSSWYNG-HRPEPGLGGGDFETFENLRQRGYQVCPVLA-----DIECRAAQLPDMPL 2083 Query: 1627 --MTKAVTVRGHGSLPVRTTPPQPSLTASPSSR----------PVASPGAISRSPTSSGS 1674 + + V L + P L R P +PG + S+ + Sbjct: 2084 EELGQQVDCDRMRGLMCANSQQSPPLCHDYELRVLCCEYVPCGPSPAPGTSPQPSLSAST 2143 Query: 1675 HKAVLTPAVTKVISRTGVPQPTQAQSAS-------SPSTPLTVAGTAAEQVPVSP 1722 AV TP T +T + +S + S S P+TV +A P Sbjct: 2144 EPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSAPGTTTCQP 2198 Score = 49.7 bits (117), Expect = 4e-05 Identities = 97/478 (20%), Positives = 160/478 (33%), Gaps = 76/478 (15%) Query: 1634 RGHGSLPVRTTPPQPSLTASPSS-----RPVASPGAISRSPTSSGSHKAVLTPAVTKVIS 1688 RG + P TT + + T + + +P +SPG ++R+P +S + L+ +T Sbjct: 2297 RGRATTPPPTTELETATTTTTQALFSTPQPTSSPG-LTRAPPASTTAVPTLSEGLTS--- 2352 Query: 1689 RTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSP 1748 P+ T ++ P T AG+ VP +T L G G +P P Sbjct: 2353 ----PRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRP-SQP 2407 Query: 1749 ASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATP-----FMSLES 1803 + P + ++ RP + A++ P P S + + +TP L + Sbjct: 2408 PTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTN 2467 Query: 1804 TRPSQLLSGLPP--------DTSLPLAKVG-----TSAPVATPGPKASVITTPLQPQATT 1850 T SQ + P D P + V T + G K ++ +A Sbjct: 2468 TTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAEN 2527 Query: 1851 LPAQTLSPVLPFTPAAM-----------------------------TQAHPPTHIAPPAA 1881 P ++ V ++ +H P+ A + Sbjct: 2528 YPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSST 2587 Query: 1882 GT---APGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1938 T PG T PT+ A T S + T +L+ + PT S+ Sbjct: 2588 ATPSSTPGTTWILTKPTTTATTTA-STGSTATPTSTLRTAPPPKVLTTTATTPT--VTSS 2644 Query: 1939 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS---YALSRVSARTAPQDSMLVLLP 1995 + P+ +P T+ L L + A + P+P+S +R+S T P +M P Sbjct: 2645 KATPSS-SPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATP 2703 Query: 1996 QLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 T H + ATT + S S G A T T T P Sbjct: 2704 S-----STPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATP 2756 Score = 35.4 bits (80), Expect = 0.83 Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 16/62 (25%) Query: 1411 RYDACASPCFQTCRDP-RAASCRD-------VPRGRSCVPVCPTPQVLDEVTQR-CVYLE 1461 ++ C SPC TC +P RA C D P GRSC VLD++T C+ L Sbjct: 990 QHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCT-------VLDDITHSGCLPLG 1042 Query: 1462 DC 1463 C Sbjct: 1043 QC 1044 Score = 34.3 bits (77), Expect = 1.9 Identities = 50/245 (20%), Positives = 93/245 (37%), Gaps = 25/245 (10%) Query: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2108 T CVP+++ CV N + + P C + GG C C Sbjct: 386 TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431 Query: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168 CS+ F TFDG + + Y+L++ D + + + L CL Sbjct: 432 GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488 Query: 2169 MLNMT-HLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2224 + ++ A V + + + +V ++ P+S I ++I S + +Q Sbjct: 489 SVTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548 Query: 2225 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2284 + + L + A K + Q GLCG + A+D G V A A F ++++ + Sbjct: 549 LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604 Query: 2285 SLTSV 2289 + ++ Sbjct: 605 ACPNI 609 >gi|134031945 SCO-spondin [Homo sapiens] Length = 5147 Score = 546 bits (1408), Expect = e-155 Identities = 350/1132 (30%), Positives = 520/1132 (45%), Gaps = 89/1132 (7%) Query: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210 C +W H TFDG +Y+ G+ +Y L G + ++++ + +C P C R Sbjct: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAAD---STWAVHLTPGDRC-PQPGHCQRVT- 249 Query: 211 LFFVGEQEIHL-AKEVTHGGMRVQLPH--VMGSARLQQLAGYVIVRHQSAFTLAWDGASA 267 +G +E+ + A V+ G V ++ LQ L ++++ + D + Sbjct: 250 ---MGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306 Query: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327 + I + EL G T GLCG N P+DD + G L F +SW+ P G + Sbjct: 307 ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR--LPGSESGCLDA 364 Query: 328 SLPRPPC-------LQQNPGTMQG-VYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ 379 C PG ++ + C LL PF CHA VSP + +C C Sbjct: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCA 424 Query: 380 SM-------GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432 G C A Y +ACA+ ++ WR C C Y++C++ Sbjct: 425 GAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQL-YSDCVSL 481 Query: 433 CPASCHP-----RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV 487 CP SC SC + CV GC CP GL + CV A CPC + Y PG Sbjct: 482 CPPSCEAVGQGEEESCREE---CVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538 Query: 488 VKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTF--PATCQYILAKSRSS 545 V++ CN C C G+W C+ A+CPAEC+V GD H+ TFDGR Y+F C+Y L + Sbjct: 539 VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598 Query: 546 GTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDA 605 G + L++ C G+C+ ++SV L + L +G VL+ Q +P + Sbjct: 599 GQLLILLEHGAC---DAGSCLHAISVSLED---THIQLRDSGAVLVNGQDVGLPWIGAEG 652 Query: 606 FEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSP 665 +RR SS FL +R G +VL+ Y+ +D R GLCGTF N QDDFL+P Sbjct: 653 LSVRRASSAFLLLRW-PGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTP 711 Query: 666 VGVPESTPQLFGNSWKTL-SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCS 724 G E++ F + ++ P + L PC H Q +++ AC++L +F C Sbjct: 712 AGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECH 771 Query: 725 AFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEAS 782 + P++ +C C C G CLC L+ YA C + G +R + C + C Sbjct: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPGG 830 Query: 783 KEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQ 842 +EY C CG+ C PE CG G CV GC CP D + CVP + Sbjct: 831 QEYRECAPACGQHC---GKPEDCGELG-------SCVAGCNCPLGLLWDPEGQ-CVPPSL 879 Query: 843 CSCHFQGVDYPPGDSDIPSLGHCHCKD-GVMSCDSR-APAAA-CPAGQVFVNCSDLHTDL 899 C C Y PG + + C C++ G+ +C +R P+ A CP V+ + L Sbjct: 880 CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACL---- 935 Query: 900 ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 959 TC+ N S A GC CP G + + C P+ CPC G+ Y P Sbjct: 936 -----LTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNAT 988 Query: 960 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS 1019 + C+ CVC+ + CT + C A G HY TFDGL F + GAC+ LV+ S + Sbjct: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL- 1047 Query: 1020 FSVIVENVNCYSSGMICRKFISINVGNSLI-------VFDDDSGNPSPESFLDDKQEVHT 1072 F+V +N+ C +SG+ C K +++ + +++ V + P+ + + Sbjct: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLR- 1106 Query: 1073 WRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLE 1132 R G F L+ +TLLWD T V VQ PQ++G++AGLCG+FD N++R+ + + Sbjct: 1107 -RAGLFLLLS-THLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164 Query: 1133 LTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTW 1191 + SW + CP+ D C +N R +A+ C LL +F +CH V Sbjct: 1165 EPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQ 1224 Query: 1192 FYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1243 Y CL D CGC GGDCEC C++++ YA +C +HG V WR+ LC C+ Sbjct: 1225 HYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276 Score = 255 bits (651), Expect = 5e-67 Identities = 153/473 (32%), Positives = 223/473 (47%), Gaps = 29/473 (6%) Query: 412 LRQCTV-HCKEKAFTYNECI---ACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC 467 L CT HC +AF E + C +C ++ DGC CP G + D C Sbjct: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968 Query: 468 VAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGR 527 V P CPC G Y P + ++EDCN C C +W C+ C +G H+ TFDG Sbjct: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028 Query: 528 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAG 587 +T+P C+Y+L + +SG FTV+ QN PCG + C ++++V L V G Sbjct: 1029 AFTYPGACEYLLVRE-ASGLFTVSAQNLPCGAS-GLTCTKALAVRLEGT----VVHMLRG 1082 Query: 588 DVLLFDQYKIIPP--YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645 + + + PP YT +RR + +FL + T++G+ +L+D G R+ +Q+ ++ Sbjct: 1083 RAVTVNGVSVTPPKVYTGPGLSLRR-AGLFLLLSTHLGLTLLWDG-GTRVLVQLSPQFRG 1140 Query: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAA 705 GLCG F+G+ +D S GV E T +L +SW+ C G PC ++ A Sbjct: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE--PGDLPHPCTMNTHRA 1198 Query: 706 SYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRR 761 ++ C L +F C A + P ++E C DAC C CLC+ +A YA C R Sbjct: 1199 GWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECAR 1258 Query: 762 HGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEG 821 HG V +R++ C+L CE + Y C C TC + PE G CVEG Sbjct: 1259 HGHHVRWRSQ-ELCSLQCEGGQVYEACGPTCPPTCHE-QHPEP-----GWHCQVVACVEG 1311 Query: 822 CACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSC 874 C CP T L A C+ C C + +PPG G+C C++G C Sbjct: 1312 CFCPEGTLLHGGA--CLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362 Score = 214 bits (546), Expect = 8e-55 Identities = 139/410 (33%), Positives = 195/410 (47%), Gaps = 23/410 (5%) Query: 104 KCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFD 163 +C P L C + G+ P N R + + G R C+A G H TFD Sbjct: 967 RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026 Query: 164 GLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-- 221 GL + G Y LV E G F++ N P CG+S TC++A+++ G +H+ Sbjct: 1027 GLAFTYPGACEYLLV--REASGL-FTVSAQNLP-CGASGLTCTKALAVRLEGTV-VHMLR 1081 Query: 222 AKEVTHGGMRVQLPHVMGSARLQ-QLAG-YVIVRHQSAFTLAWDGASAVYIKMSPELLGW 279 + VT G+ V P V L + AG ++++ TL WDG + V +++SP+ G Sbjct: 1082 GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGR 1141 Query: 280 THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNP 339 GLCG+ + D +DL + G L HSW+ P P LP P + N Sbjct: 1142 VAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGDLPHPCTM--NT 1195 Query: 340 GTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARA 397 +C ALL+P F CHA V P C D C S GD C A+A YA Sbjct: 1196 HRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255 Query: 398 CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCH---PRASCVDSEIACVDGC 454 CA+ G ++ WR+Q C++ C E Y C CP +CH P +ACV+GC Sbjct: 1256 CARHGHHVR-WRSQ-ELCSLQC-EGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGC 1312 Query: 455 YCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWEC 504 +CP G + G C+ PA CPCE+ +PPGSV+++DC CTC G+W C Sbjct: 1313 FCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362 Score = 146 bits (369), Expect = 3e-34 Identities = 152/516 (29%), Positives = 203/516 (39%), Gaps = 72/516 (13%) Query: 408 WRTQLRQCT-----VHCKE---KAFTYNECIACCPASCHPRASCVDSEIACVDGCYC-PN 458 W +R C HC E KA C A C +A ++ ++ C P Sbjct: 87 WNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW--QCQLQAGSANASAGSLEECCARPW 144 Query: 459 GLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECSTAVCPAECSVTG 517 G + DG A C + + PGS G+ A C+ Sbjct: 145 GQSWWDGSSQACRSC-----SSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWS 199 Query: 518 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 577 H+ TFDGR Y F C Y+LA + S T+ V L Q G C Q V++ Sbjct: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADS-TWAVHLTPGD-RCPQPGHC-QRVTM------ 250 Query: 578 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS----SVFLRVRTNVGVRVLYDREGL 633 + L QAG+V + Q ++P ++ + LS +L + +GV V DR G Sbjct: 251 GPEEVLIQAGNVSVKGQ--LVP--EGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG- 305 Query: 634 RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK-------TLSAC 686 + + VD T GLCG +NG +DDF+ P G FGNSW+ L A Sbjct: 306 SISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV 365 Query: 687 SPLVSGSPLDPCDV-----HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741 PL D HL+A + V C L F C A +SP Y E C C Sbjct: 366 EVAQGCDPLGLIDADVEPGHLRAEAQDV--CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423 Query: 742 RCG---------QPCLCATLAHYAHLC-RRHGLPVDFRARLPA-CALSCEASKEYSPCVA 790 Q +CAT A Y C RRH + R R P C C + YS CV+ Sbjct: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRH---IHIRWRKPGFCERLCPGGQLYSDCVS 480 Query: 791 PCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGV 850 C +C EA G G ++ R+ECV GC CP + + LCVP C C++ Sbjct: 481 LCPPSC------EAVG-QGEEESCREECVSGCECPRGLFWN--GTLCVPAAHCPCYYCRQ 531 Query: 851 DYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAG 886 Y PGD+ C C+DG C A C G Sbjct: 532 RYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVG 567 Score = 98.2 bits (243), Expect = 1e-19 Identities = 133/533 (24%), Positives = 184/533 (34%), Gaps = 114/533 (21%) Query: 2105 WEC-----ACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGH 2159 W C + RC +VTFDG Y+L + + TV + G Sbjct: 1003 WHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASG- 1061 Query: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPP--VSRYGFRIEDTGHMYMILT 2217 L V L T + H + R VTV+ V PP + G + G ++ T Sbjct: 1062 LTCTKALAVRLEGT-VVHMLR----GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLST 1116 Query: 2218 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2277 + + W ++V+ S + + GLCG DGDA+NDL + G + AE A Sbjct: 1117 HLGLTLLW-DGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAA--- 1172 Query: 2278 DSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHRFVPPESF 2328 SW++ G P C A C L+ + F+ CH VPP+ Sbjct: 1173 HSWRLSPLCPEPGDL---PHPCTMNTHRAGWARARCGALLQPL----FTLCHAEVPPQQH 1225 Query: 2329 CELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACV 2382 E + D C A+ Y C + + WR + C C Y+AC Sbjct: 1226 YEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACG 1285 Query: 2383 TACEPPKTCQDGILGPLDPEHCQVLG--EGCVCSEGTILHRRHSALCIPEAKCACTDSMG 2440 C P TC + P HCQV+ EGC C EGT+L H C+ A C C Sbjct: 1286 PTC--PPTCHE--QHPEPGWHCQVVACVEGCFCPEGTLL---HGGACLEPASCPC----- 1333 Query: 2441 VPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500 W P +++ D G +C C Sbjct: 1334 -------EWG--------RNSFPPGSVLQKDCG-------NC--------------TCQE 1357 Query: 2501 GT-VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD-PDLC------EAELVP 2552 G C + CE L P C G L QE+ C + CD D C E P Sbjct: 1358 GQWHCGGDGGHCEELVPACAEGEALC---QENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414 Query: 2553 SCRQDQILITGRLGDSCCTSYFC----ACGD--------CPDSIPECQEGEAL 2593 C + Q +T G + C CGD CP + C +G L Sbjct: 1415 GCGEGQ--MTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCL 1465 Score = 85.1 bits (209), Expect = 9e-16 Identities = 43/133 (32%), Positives = 59/133 (44%), Gaps = 10/133 (7%) Query: 388 CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC------CPASCHPRA 441 C +LA C + TQ CT C E + C CP C + Sbjct: 2857 CSSLAPGDTTCPGPHSQTRDCNTQ--PCTAQCPENML-FRSAEQCHQEGGPCPRLCLTQG 2913 Query: 442 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED-CNTCTCTSG 500 ++ C GC CP GL + C+ ++CPC+ HG LY G++ + D CN CTC SG Sbjct: 2914 PGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSG 2973 Query: 501 KWECSTAVCPAEC 513 K C++ CP C Sbjct: 2974 KMACTSERCPVAC 2986 Score = 81.6 bits (200), Expect = 1e-14 Identities = 96/400 (24%), Positives = 144/400 (36%), Gaps = 59/400 (14%) Query: 2068 QLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR----CSIFPDLSFVTFD 2123 Q R S+H P A+ P + LA VG LW R C+ + + TFD Sbjct: 154 QACRSCSSRHLPGSASSPAL-LQPLAGAVG-----QLWSQHQRPSATCASWSGFHYRTFD 207 Query: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHLNWPPFCLVMLNMTHLAHQVTID 2182 G H Y+L+ + D VH+ + GH +T +V I Sbjct: 208 GRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQ---------RVTMGPEEVLIQ 258 Query: 2183 RFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2242 N V L P +G ++ G +++L+ + L +G + + Sbjct: 259 AGNVSVKGQLVPEGQSWLLHGLSLQWLGD-WLVLSGGLGVVVRLDRTGSISISVDHELWG 317 Query: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC--- 2299 Q GLCG+ +G +D G G A A F +SW++P S + C Sbjct: 318 QTQGLCGLYNGWPEDDFMEPGG---GLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPL 374 Query: 2300 --ATTDCSP----------CLRMVSNRTFSACHRFVPPESFCELWI-----------RDT 2336 D P C +++ F CH V P + E + Sbjct: 375 GLIDADVEPGHLRAEAQDVCHQLLEG-PFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQE 433 Query: 2337 KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2396 Q C YV C + H+ I WR+ +C LC Y CV+ C P +C+ + Sbjct: 434 GRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLC--PPSCE--AV 489 Query: 2397 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435 G + E C + GC C G + LC+P A C C Sbjct: 490 GQGEEESCREECVSGCECPRGLFW---NGTLCVPAAHCPC 526 Score = 73.9 bits (180), Expect = 2e-12 Identities = 42/129 (32%), Positives = 60/129 (46%), Gaps = 14/129 (10%) Query: 395 ARACAQ-----AGRPLQGWRTQLRQCT-VHCKEKAFTYNECIAC---CPASCHPRAS--- 442 +R+C+ G P G R Q R C + C+ E + C CP C Sbjct: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIV 4087 Query: 443 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPGSVVKEDCNTCTCTSGK 501 C D ++ C GC CP G + +DGGCV C C + G + PGS ++ CN C+C +G+ Sbjct: 4088 CQDDQV-CQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQ 4146 Query: 502 WECSTAVCP 510 C+ CP Sbjct: 4147 LSCTAQPCP 4155 Score = 72.4 bits (176), Expect = 6e-12 Identities = 97/423 (22%), Positives = 136/423 (32%), Gaps = 146/423 (34%) Query: 678 NSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCR 737 + W S C P + S L P A+ +++ + +P L+P+ EQ R Sbjct: 4526 SEWSEWSPCGPCLPPSALAP------ASRTALEEHWLRDPTGLSPT---LAPLLASEQHR 4576 Query: 738 RDACR--------CGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK--EYSP 787 C G P LC LC G AC SC+ S +SP Sbjct: 4577 HRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPG----------ACPDSCQWSLWGPWSP 4626 Query: 788 CVAPC---------------GRTCQDLASPEACGVDGG---------------------- 810 C PC G C++ + E+C +GG Sbjct: 4627 CQVPCSGGFRLRWREAEALCGGGCREPWAQESC--NGGPCPECEAQDTVFTLDCANQCPH 4684 Query: 811 ---DDLSRDECVEG-----CACPPDTYLDTQADLCVPRNQCSCHFQGV----DYPPGDSD 858 D R +C++G C CPP + Q CVP + C C + P + Sbjct: 4685 SCADLWDRVQCLQGPCRPGCRCPPGQLV--QDGRCVPISSCRCGLPSANASWELAPAQAV 4742 Query: 859 IPSLGHCHCKDGVMSCDSRAPAAACPA---GQVFVNCSDLHTDLELSRERTCE------- 908 +C C + + C P CP + +CS + R RTCE Sbjct: 4743 QLDCQNCTCVNESLVC----PHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798 Query: 909 --------QQLLNL-----------------------------SVSARGPCLSGCACPQG 931 +Q NL ++ + PC GC CP G Sbjct: 4799 CQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGG 4858 Query: 932 LLRHGDACFLPEECPCT-----W--------KGKEYFPGDQVMSPCHTCVCQRGSFQCTL 978 L H C P CPCT W + +E PG + C CVC G+F C+L Sbjct: 4859 QLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSL 4918 Query: 979 HPC 981 C Sbjct: 4919 VDC 4921 Score = 70.9 bits (172), Expect = 2e-11 Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 6/78 (7%) Query: 434 PASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN 493 PASC ++ + C GC+CP+G++ + CV +CPC G LYPPGS V C Sbjct: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162 Query: 494 TCTCTSG------KWECS 505 C+C SG W C+ Sbjct: 3163 NCSCVSGLIANCSSWPCA 3180 Score = 70.9 bits (172), Expect = 2e-11 Identities = 54/221 (24%), Positives = 72/221 (32%), Gaps = 28/221 (12%) Query: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838 C + S C C C L C ++ C GC CP L CV Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQPGAIC--------VQEPCQPGCGCPGGQLLHNGT--CV 4867 Query: 839 PRNQCSC-------------HFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPA 885 P C C Q + PPG + C C G SC P Sbjct: 4868 PPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS--LVDCQVPP 4925 Query: 886 GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE- 944 G+ + + +L L + E + SGC C G R +PE+ Sbjct: 4926 GETWQQVAP--GELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983 Query: 945 CPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTC 985 C C G+ + PG + C +C+C G CT H TC Sbjct: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024 Score = 70.1 bits (170), Expect = 3e-11 Identities = 89/374 (23%), Positives = 143/374 (38%), Gaps = 65/374 (17%) Query: 917 SARGPCLSGCACP-QGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQR---- 971 S G C + C Q + A L E C W G+ ++ G C +C + Sbjct: 111 SPEGHCFAMWQCQLQAGSANASAGSLEECCARPW-GQSWWDGSS--QACRSCSSRHLPGS 167 Query: 972 GSFQCTLHPCA--------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 1017 S L P A +TC ++ HYRTFDG + F+G C +L+ +D Sbjct: 168 ASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRC-TYLLAGAAD 226 Query: 1018 VSFSV-IVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076 +++V + C G R + +G ++ +GN S + L E +W + Sbjct: 227 STWAVHLTPGDRCPQPGHCQR----VTMGPEEVLI--QAGNVSVKGQL--VPEGQSWLLH 278 Query: 1077 FFT-------LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPE 1129 + LV + + D+ ++ + + GQ GLCG ++ ++ P Sbjct: 279 GLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPG 338 Query: 1130 NLELTNPQEFGSSWA----------AVECPDTLDPRDMCVLNPLREP-----FAKKECSI 1174 FG+SW AVE DP + +++ EP A+ C Sbjct: 339 GGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDP--LGLIDADVEPGHLRAEAQDVCHQ 396 Query: 1175 LLSEVFEICHPVVDVTWFYSNCLTDTC-----GCSQGGDCECFCASVSAYAHQCCQHGVA 1229 LL F CH V ++ CL C G Q G + CA+ ++Y C + + Sbjct: 397 LLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456 Query: 1230 VDWRTP----RLCP 1239 + WR P RLCP Sbjct: 457 IRWRKPGFCERLCP 470 Score = 70.1 bits (170), Expect = 3e-11 Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 50/239 (20%) Query: 313 WQEQAPNQPP--GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFT 370 W E P G T S C G E EA + +AC +Y Sbjct: 3414 WSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY------- 3466 Query: 371 ASCTSDLCQSMGDVATW-----CRALAEYARACA-----QAGRPLQGWRTQLRQC---TV 417 A+C D + G W C + +RAC+ + GRP G TQ R C + Sbjct: 3467 ATCPVD--GAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENST 3524 Query: 418 HCKE--KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE 472 C + + + C CP SC P + C + C C CP G + +DG CV PA Sbjct: 3525 QCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAH 3584 Query: 473 CPCEFH--------------GTLY------PPGSVVKEDCNTCTCTSGKWECSTAV-CP 510 C C++ G+ + PG VV C+ CTC +G +C CP Sbjct: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643 Score = 70.1 bits (170), Expect = 3e-11 Identities = 49/166 (29%), Positives = 61/166 (36%), Gaps = 31/166 (18%) Query: 373 CTSDLCQSMGDVATWCRALA-------EYARAC--AQAGRPLQGWRTQLRQ-CTVH-CKE 421 C C +G + W A E R C P Q T+ RQ C + C E Sbjct: 4758 CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPE 4817 Query: 422 --KAFTYNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCE 476 + C CP C P A CV C GC CP G + +G CV P CPC Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGCGCPGGQLLHNGTCVPPTACPCT 4875 Query: 477 FHGTLY-------------PPGSVVKEDCNTCTCTSGKWECSTAVC 509 H + PPG+V+ +C C C G + CS C Sbjct: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921 Score = 69.7 bits (169), Expect = 4e-11 Identities = 55/208 (26%), Positives = 73/208 (35%), Gaps = 19/208 (9%) Query: 788 CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHF 847 C+AP G S C G D E PP + + L P + CS Sbjct: 2788 CLAPGGGPGWRSRS-RLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPC 2846 Query: 848 QG---------VDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTD 898 G PGD+ P H +D C+++ A CP +F + H + Sbjct: 2847 DGGIQTRGRSCSSLAPGDTTCPG-PHSQTRD----CNTQPCTAQCPENMLFRSAEQCHQE 2901 Query: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGD 958 R C Q + G C GC CP GL H +C +CPC G+ Y G Sbjct: 2902 GGPC-PRLCLTQ--GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGA 2958 Query: 959 QV-MSPCHTCVCQRGSFQCTLHPCASTC 985 + C+ C C G CT C C Sbjct: 2959 MARLDSCNNCTCVSGKMACTSERCPVAC 2986 Score = 68.9 bits (167), Expect = 7e-11 Identities = 69/260 (26%), Positives = 85/260 (32%), Gaps = 67/260 (25%) Query: 772 LPACALSCEASK--EYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTY 829 LP +C A + EYSPC PC R+C DL C GC CPP Sbjct: 3304 LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW------------RCQPGCYCPPGQV 3351 Query: 830 LDTQADLCVPRNQCSC--HFQGVDYPPGD--SDIPSLGHCHCKDGVMSCDS---RAPAAA 882 L + +CV CSC G + PG + HC C +G ++C P Sbjct: 3352 LSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGW 3411 Query: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942 CP + + CS SR R C PC +G A G +AC Sbjct: 3412 CPWSE-WTMCSQPCRGQTRSRSRAC---ACPTPQHGGAPC-TGEAGEAGAQHQREACPSY 3466 Query: 943 EECPCTWKGKEYFPGDQVMSPCHTCV------------------------------CQRG 972 CP + P SPC C+ CQ Sbjct: 3467 ATCPVDGAWGPWGP----WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQEN 3522 Query: 973 SFQCT-------LHPCASTC 985 S QCT LHPC C Sbjct: 3523 STQCTDCGGGQSLHPCGQPC 3542 Score = 68.9 bits (167), Expect = 7e-11 Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 31/208 (14%) Query: 330 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATW-- 387 P PC + + C L+ C++ L T C S C ++W Sbjct: 4315 PWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLD-TQGCYSGPCPEECVWSSWSS 4373 Query: 388 -----CRALAEY-------ARACAQAGRPLQGWRTQLRQCTV-HCKEKA----FTYNECI 430 CR L + A A+AG P R C + +C E + F ++ C Sbjct: 4374 WTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACG 4433 Query: 431 ACCPASCHPRAS---CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFH------GTL 481 + C C S C D C GCYCP GL+ + GGC+ P EC C +H G Sbjct: 4434 SPCAGLCATHLSHQLCQDLP-PCQPGCYCPKGLLEQAGGCIPPEECNC-WHTSAAGAGMT 4491 Query: 482 YPPGSVVKEDCNTCTCTSGKWECSTAVC 509 PG ++ C C C G+ C++ C Sbjct: 4492 LAPGDRLQLGCKECECRRGELHCTSQGC 4519 Score = 66.6 bits (161), Expect = 3e-10 Identities = 131/556 (23%), Positives = 193/556 (34%), Gaps = 101/556 (18%) Query: 2029 LSIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCG 2088 +S+ EA+ E + CV E C R + G L + HCP R Sbjct: 479 VSLCPPSCEAVGQGEEESCREECVSGCE--CPRGLFWNGTLCV--PAAHCPCYYCRQRY- 533 Query: 2089 ILGLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALF--KEAIYILS 2138 + G VR + C W CA C++ D ++TFDG + + + Y L Sbjct: 534 VPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLV 593 Query: 2139 QSPDEMLTVHVLDCKSANLGHLNWPPFCL----VMLNMTHLAHQVTIDRFNRKVTVDLQP 2194 Q + + +L+ + + G CL V L TH+ R + V V+ Q Sbjct: 594 QDYVKGQLLILLEHGACDAGS------CLHAISVSLEDTHIQL-----RDSGAVLVNGQD 642 Query: 2195 VWPP-VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDG 2253 V P + G + +++L Q+ W S + + Q GLCG Sbjct: 643 VGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQ 702 Query: 2254 DAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------SSLTSVGQTRFRPDSCATTDC 2304 + +D G V A F +QV S+L S T + + A C Sbjct: 703 NQQDDFLTPAGDVETSI---AAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAAC 759 Query: 2305 SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV-------QQPCVALTVYVAMCHKFH 2357 + ++ + F CHR V E F ++R V C L+ Y C + Sbjct: 760 A----ILHSSVFQECHRLVDKEPF---YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG 812 Query: 2358 VCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGE---GCVCS 2414 WR CP +C Y+ C AC + C PE C LG GC C Sbjct: 813 ASPPWRNQTLCPVMCPGGQEYRECAPAC--GQHCG-------KPEDCGELGSCVAGCNCP 863 Query: 2415 EGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC 2474 G + C+P + C C +G R ++++ C + CQ C Sbjct: 864 LGLLWD--PEGQCVPPSLCPC--QLGARRY--APGSATMKECNRCICQERGLWNCTARHC 917 Query: 2475 PS----PRPESCLRFGEVALLLPTKDP-----CCLGTVCVCNQTLCEGLAPTCRPGHRLL 2525 PS PR L + A LL P C G+ C C PG LL Sbjct: 918 PSQAFCPRE---LVYAPGACLLTCDSPSANHSCPAGSTDGC----------VCPPGTVLL 964 Query: 2526 THFQEDSCCPSYSCEC 2541 ++ C P C C Sbjct: 965 ----DERCVPPDLCPC 976 Score = 66.6 bits (161), Expect = 3e-10 Identities = 78/351 (22%), Positives = 107/351 (30%), Gaps = 125/351 (35%) Query: 746 PC-LCATLAHYAHLCRRHGLPVDFR------ARLPAC------ALSCEASKEYSPCVAPC 792 PC +C +H + C R P R + C C + PC PC Sbjct: 3483 PCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542 Query: 793 GRTCQDLASPEAC--GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ-- 848 R+CQDL+ C G G C C CP +Q LCVP C C +Q Sbjct: 3543 PRSCQDLSPGSVCQPGSVG--------CQPTCGCPLGQL--SQDGLCVPPAHCRCQYQPG 3592 Query: 849 --GV----------------DYPPGDSDIPSLGHCHCKDGVMSCD--------------- 875 G+ PG+ +C C G++ C Sbjct: 3593 AMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWG 3652 Query: 876 --------------------SRAPA-----------------AACPAGQVFVNCSDLHTD 898 +R P A CPAG+++ C Sbjct: 3653 PWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGE-- 3710 Query: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPC---TW------ 949 +C + + G C GC CP+G +H AC +ECPC W Sbjct: 3711 ---GCPFSCAHVTQQVGCFSEG-CEEGCHCPEGTFQHRLACV--QECPCVLTAWLLQELG 3764 Query: 950 -----KGKEYFPGDQVMS------PCHTCVCQRGSFQCTLHPCASTCTAYG 989 G+ PGD++ S C C C G C+L C +G Sbjct: 3765 ATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFG 3815 Score = 64.7 bits (156), Expect = 1e-09 Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%) Query: 389 RALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEI 448 + L +Y G Q + CT + Y+ C CP SC CV Sbjct: 3285 QGLGDYCEGPRAQGEVCQALPCPVTNCTAI---EGAEYSPCGPPCPRSCDDLVHCV---W 3338 Query: 449 ACVDGCYCPNGLIFEDGG--CVAPAECPCE--FHGTLYPPGSVVK--EDCNTCTCTSGKW 502 C GCYCP G + G CV P C C G + PG+ + + CN CTC G+ Sbjct: 3339 RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398 Query: 503 ECSTAVCP 510 C+ CP Sbjct: 3399 NCTDLPCP 3406 Score = 64.3 bits (155), Expect = 2e-09 Identities = 34/109 (31%), Positives = 42/109 (38%), Gaps = 8/109 (7%) Query: 874 CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLL 933 C+ A CPAG V C++ R C + C GC CP+G L Sbjct: 4053 CNPMPCEAGCPAGMEVVTCAN-------RCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSL 4105 Query: 934 RHGDACFLPEECPCT-WKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 981 C C CT +G + PG Q C+ C CQ G CT PC Sbjct: 4106 EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154 Score = 63.9 bits (154), Expect = 2e-09 Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 8/139 (5%) Query: 850 VDYPP--GDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTC 907 VD PP G + P G+ C C G+V+V+ L +C Sbjct: 2583 VDPPPKNGGAPCPGASQERAPCGLQPCSG---GTDCELGRVYVSADLCQKGLVPPCPPSC 2639 Query: 908 EQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG-DQVMSPCHT 966 N S S G C+ GC CP GLL H C ECPC + +PG ++ C Sbjct: 2640 LDPKANRSCS--GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQ 2697 Query: 967 CVCQRGSFQCTLHPCASTC 985 CVC++G C C C Sbjct: 2698 CVCEKGELLCQPGGCPLPC 2716 Score = 62.4 bits (150), Expect = 6e-09 Identities = 56/203 (27%), Positives = 73/203 (35%), Gaps = 39/203 (19%) Query: 330 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHA--YVSPLPFTASCTSDLCQSMGDVATW 387 P PC + QG +C L C + S FTA+C D G+ +TW Sbjct: 1702 PWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVD-----GEWSTW 1756 Query: 388 ---------CRALAEYARACAQAGRPLQGWRT------------QLRQCTVHCKEKAFTY 426 CR R C P G RT Q + C A Sbjct: 1757 SPWSVCSEPCRGTMTRQRQCHS---PQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCS 1813 Query: 427 NECI----ACCPASCHP---RASCVDSEIACVDGCYCPNGLIF-EDGGCVAPAECPCEFH 478 E + A CP +C + +C GC+CP G + +G CV P +CPC Sbjct: 1814 GELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVD 1873 Query: 479 GTLYPPGSVVKEDCNTCTCTSGK 501 G Y PG +K DC C C G+ Sbjct: 1874 GARYWPGQRIKADCQLCICQDGR 1896 Score = 62.4 bits (150), Expect = 6e-09 Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 7/85 (8%) Query: 433 CPASC-HPRA--SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG-SVV 488 CP SC P+A SC CV+GC CP GL+ D C+ +ECPC L PG S + Sbjct: 2635 CPPSCLDPKANRSCSGH---CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFL 2691 Query: 489 KEDCNTCTCTSGKWECSTAVCPAEC 513 +C+ C C G+ C CP C Sbjct: 2692 LGNCSQCVCEKGELLCQPGGCPLPC 2716 Score = 62.0 bits (149), Expect = 8e-09 Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 14/115 (12%) Query: 870 GVMSCDSRAPAAACPAGQVFVNCSDLHTDL-ELSRERTCEQQLLNLSVSARGPCLSGCAC 928 G+ C P CP + +++C+ ELS R Q C GC C Sbjct: 3078 GLQPCAGPVPGM-CPRDKQWLDCAQGPASCAELSAPRGTNQT-----------CHPGCHC 3125 Query: 929 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSF-QCTLHPCA 982 P G+L + C ++CPC +G Y PG V+ PC C C G C+ PCA Sbjct: 3126 PSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180 Score = 61.6 bits (148), Expect = 1e-08 Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%) Query: 921 PCLSGCACPQGLLRHGDACFLPEECPC-----TWKGKEYFPGDQVMSPCHTCVCQRGSFQ 975 PC GC CP+GLL C PEEC C G PGD++ C C C+RG Sbjct: 4454 PCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELH 4513 Query: 976 CTLHPC 981 CT C Sbjct: 4514 CTSQGC 4519 Score = 60.5 bits (145), Expect = 2e-08 Identities = 62/231 (26%), Positives = 83/231 (35%), Gaps = 38/231 (16%) Query: 779 CEASKEYSPCVAPCGRTCQDLASPEA--CGVDG--------GDDLSRDECVEGCACPPDT 828 C A +SP PC RTC + C G G + C ACP D Sbjct: 1694 CGAWGPWSPW-GPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTA-ACPVDG 1751 Query: 829 YLDTQADLCVPRNQC--------SCHFQGVDYPPGDSDIPSL-GHCHCKDGVMSC-DSRA 878 T + V C CH G +L G H C Sbjct: 1752 EWSTWSPWSVCSEPCRGTMTRQRQCHSP----QNGGRTCAALPGGLHSTRQTKPCPQDGC 1807 Query: 879 PAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS-GCACPQGLLRHGD 937 P A C +F C+ TC+ ++ PC S GC CP+G + + Sbjct: 1808 PNATCSGELMFQPCAPCPL--------TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE 1859 Query: 938 A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG-SFQCTLHP-CASTC 985 C P +CPC G Y+PG ++ + C C+CQ G +C L+P CA C Sbjct: 1860 GWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910 Score = 58.2 bits (139), Expect = 1e-07 Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 25/137 (18%) Query: 749 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 808 CA H A LC + +P C C A E C C R C DL C D Sbjct: 4043 CAGERHQARLC--NPMP---------CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDD 4091 Query: 809 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC-HFQGVDYPPGDSDIPSLGHCHC 867 C +GC CP + Q CVP C C QG + PG + +C C Sbjct: 4092 -------QVCQKGCRCPKGSL--EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSC 4142 Query: 868 KDGVMSCDSRAPAAACP 884 + G +SC A CP Sbjct: 4143 QAGQLSC----TAQPCP 4155 Score = 53.9 bits (128), Expect = 2e-06 Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 9/90 (10%) Query: 428 ECIACCPASCHP---RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT---- 480 +C CP SC R C+ C GC CP G + +DG CV + C C Sbjct: 4677 DCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASW 4734 Query: 481 LYPPGSVVKEDCNTCTCTSGKWECSTAVCP 510 P V+ DC CTC + C CP Sbjct: 4735 ELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764 Score = 51.2 bits (121), Expect = 1e-05 Identities = 85/323 (26%), Positives = 111/323 (34%), Gaps = 81/323 (25%) Query: 2368 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2424 CP C AC T+C P C Q G + +P CQ GC C G +LH + Sbjct: 4815 CPE-CPPGQVLSACATSC--PCLCWHLQPGAICVQEP--CQ---PGCGCPGGQLLH---N 4863 Query: 2425 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVP--------------- 2469 C+P C CT +P W +L+ Q Q P T++ Sbjct: 4864 GTCVPPTACPCTQH-SLP------WGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSC 4916 Query: 2470 --VDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPT---CRPGHRL 2524 VD P + GE+ L T CL Q+ C + C+PGH Sbjct: 4917 SLVDCQVPPGETWQQVAPGELGLCEQT----CLEMNATKTQSNCSSARASGCVCQPGH-- 4970 Query: 2525 LTHFQEDSCCPSYSCEC----DPDL--------CEAELV----PSCRQDQILITGRLGDS 2568 Q C P CEC P L CE+ L P C Q +T G+ Sbjct: 4971 -FRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEE 5029 Query: 2569 CCTSYFCACGDCPDSIPECQEG--EALTVHRNTTELCCPLYQ---CVCENFRCPQVQCGL 2623 C C PE Q + LT RN T+ C L Q C + C Sbjct: 5030 MVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGY------CPS 5083 Query: 2624 GTALVEVWSPDRCCPYKSCECDC 2646 T ++ P+ PY +CDC Sbjct: 5084 STHVM----PEE--PYLQSQCDC 5100 Score = 50.1 bits (118), Expect = 3e-05 Identities = 42/143 (29%), Positives = 52/143 (36%), Gaps = 32/143 (22%) Query: 395 ARACAQAGRPLQGWRTQLRQCTVH-CKEKAFT----YNECIAC--CPASC-HPRASCVDS 446 +R CA+ P G Q R C+ C+E Y EC CP SC H Sbjct: 3669 SRRCARP--PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCF 3726 Query: 447 EIACVDGCYCPNGLIFEDGGCVAPAECPC--------EFHGTLYPPGS------------ 486 C +GC+CP G CV ECPC E T+ PG Sbjct: 3727 SEGCEEGCHCPEGTFQHRLACVQ--ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQ 3784 Query: 487 VVKEDCNTCTCTSGKWECSTAVC 509 ++ C C+C GK CS C Sbjct: 3785 TLRTSCGNCSCAHGKLSCSLDDC 3807 Score = 49.3 bits (116), Expect = 6e-05 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 12/103 (11%) Query: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838 C K++ C A +C +L++P + C GC CP L ++CV Sbjct: 3090 CPRDKQWLDC-AQGPASCAELSAPRG---------TNQTCHPGCHCPSGMLLLN--NVCV 3137 Query: 839 PRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAA 881 P C C +G YPPG + + +C C G+++ S P A Sbjct: 3138 PTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180 Score = 48.9 bits (115), Expect = 7e-05 Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 14/115 (12%) Query: 778 SCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837 SC E+ C +PC C S + C DL C GC CP L QA C Sbjct: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLC-----QDL--PPCQPGCYCPKG--LLEQAGGC 4472 Query: 838 VPRNQCSCHF-----QGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQ 887 +P +C+C G+ PGD C C+ G + C S+ P + Sbjct: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSE 4527 Score = 47.8 bits (112), Expect = 2e-04 Identities = 71/335 (21%), Positives = 109/335 (32%), Gaps = 70/335 (20%) Query: 680 WKTLSACSPLVSGSPLD------------PCDVH--LQAASYSVQACSVLT-GEMFAPCS 724 W S+CS G ++ PC Q ++Q C G++ + C+ Sbjct: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828 Query: 725 AFLSPVPYFEQ----CRRDACRCGQPCLCATLAHY-------AHLCRRHGLPVDFRARL- 772 + + Q C ++ C+ G C L H A C +H LP L Sbjct: 4829 TSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLE 4888 Query: 773 -------PACALSCEASK----------EYSPCVAPCGRTCQDLASPE------ACGVDG 809 P L+ ++ C P G T Q +A E C ++ Sbjct: 4889 EQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTC-LEM 4947 Query: 810 GDDLSRDEC----VEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 865 ++ C GC C P + +QA CVP + C C G + PG + C Sbjct: 4948 NATKTQSNCSSARASGCVCQPG-HFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESC 5006 Query: 866 HCKDGVMSCDSRAPAAACPAGQVFV-----NCSDLHTDLELSRERTCEQQLLNLSVSARG 920 C G C C G+ V C + + +C Q L L +G Sbjct: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSC-QLLTELRNFTKG 5065 Query: 921 PC------LSGCA--CPQGLLRHGDACFLPEECPC 947 C +S C+ CP + +L +C C Sbjct: 5066 TCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC 5100 Score = 46.6 bits (109), Expect = 4e-04 Identities = 54/201 (26%), Positives = 66/201 (32%), Gaps = 46/201 (22%) Query: 822 CACPPDTYLDTQADLCVPRNQ---CS--------CHFQGVDYPPGDSDIPSLGHCH--CK 868 CA P T A L +P CS C QG D G HC C Sbjct: 3210 CARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCG 3269 Query: 869 DGVMS----CDSRAP------------------AAACPAGQVFVNCSDLHTDLELSRERT 906 G+ S CD P A CP NC+ + Sbjct: 3270 GGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPV----TNCTAIEGAEYSPCGPP 3325 Query: 907 CEQQLLNLSVSARGPCLSGCACPQG--LLRHGDACFLPEECPCT--WKGKEYFPGDQVMS 962 C + +L V C GC CP G L +G C P C C G+ + PG ++ Sbjct: 3326 CPRSCDDL-VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLAR 3384 Query: 963 P--CHTCVCQRGSFQCTLHPC 981 P C+ C C G CT PC Sbjct: 3385 PDGCNHCTCLEGRLNCTDLPC 3405 Score = 45.4 bits (106), Expect = 8e-04 Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 36/226 (15%) Query: 2368 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2424 C C + C C P+ C Q+GI+ D QV +GC C +G++ Sbjct: 4058 CEAGCPAGMEVVTCANRC--PRRCSDLQEGIVCQDD----QVCQKGCRCPKGSL---EQD 4108 Query: 2425 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC---PSPRPES 2481 C+P C CTD+ G A G + + C CQA L C P P P Sbjct: 4109 GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC---SCQAG------QLSCTAQPCPPPTH 4159 Query: 2482 CLRFGEVALLLPTKDPC-CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCE 2540 C + + P C G + AP CR + CP SC Sbjct: 4160 C-AWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ------SQSQPCPQPSC- 4211 Query: 2541 CDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPE 2586 P LC + S + G CT C D ++PE Sbjct: 4212 --PPLC-LQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPE 4254 Score = 44.7 bits (104), Expect = 0.001 Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Query: 449 ACVDGCYC-PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 507 A GC C P + G CV C C G + PGS +E C +C C SG+ C+ Sbjct: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQH 5018 Query: 508 VCPAECS 514 P C+ Sbjct: 5019 CSPLTCA 5025 Score = 43.1 bits (100), Expect = 0.004 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 14/88 (15%) Query: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSCHF 847 V PC +C D + +C CVEGC CPP L DT+ C+P ++C C Sbjct: 2632 VPPCPPSCLDPKANRSCS---------GHCVEGCRCPPGLLLHDTR---CLPLSECPCLV 2679 Query: 848 -QGVDYPPGDSDIPSLGHCHCKDGVMSC 874 + + +P + + C C+ G + C Sbjct: 2680 GEELKWPGVSFLLGNCSQCVCEKGELLC 2707 Score = 35.4 bits (80), Expect = 0.83 Identities = 86/396 (21%), Positives = 118/396 (29%), Gaps = 71/396 (17%) Query: 2301 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ-QPCVALTVYVAMCHKFHVC 2359 +T +PC + R S C P ++ C T+ QPC A + C Sbjct: 2840 STCSAPCDGGIQTRGRS-CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQC 2898 Query: 2360 IEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL------GPLDPEHCQVLGEGCVC 2413 + CP LC + C C P TC G+ P CQ+ G+ Sbjct: 2899 HQ--EGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYAS 2956 Query: 2414 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNS-SLSGCCQHQCQA-------PD 2465 L ++ C+ K ACT S P A G W+ +L C C Sbjct: 2957 GAMARLDSCNNCTCV-SGKMACT-SERCPVACG--WSPWTLWSLCSCSCNVGIRRRFRAG 3012 Query: 2466 TIVPVDLG---CPSPRPESCLRFGEVALLLPTKDPCC-LGTVCVCNQTLCEGLAPTCRPG 2521 T P G C P E+ E L P P G C + C G Sbjct: 3013 TAPPAAFGGAECQGPTMEA-----EFCSLRPCPGPGGEWGPWSPC--------SVPCGGG 3059 Query: 2522 HRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCP 2581 +R T S +C P C + C +D+ + G + C G Sbjct: 3060 YRNRTRGSSRSLMEFSTCGLQP--CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQ 3117 Query: 2582 DSIPECQEGEALTVHRNTTELCCPLYQCVC----------ENFRCPQVQCGLGTALV--- 2628 P C + + N +C P C C P C + L+ Sbjct: 3118 TCHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANC 3174 Query: 2629 ---------EVWSPDRCCPYKSCECDCDTIPVPRCH 2655 WSP P+ C C RCH Sbjct: 3175 SSWPCAEGEPTWSP--WTPWSQCSASCGP---ARCH 3205 Score = 34.7 bits (78), Expect = 1.4 Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 32/104 (30%) Query: 2391 CQDGILGP-----LDPE-------HCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDS 2438 CQ G++ P LDP+ HC EGC C G +L H C+P ++C C Sbjct: 2627 CQKGLVPPCPPSCLDPKANRSCSGHCV---EGCRCPPGLLL---HDTRCLPLSECPC--- 2677 Query: 2439 MGVPRALGE--TW---NSSLSGCCQHQCQAPDTIVPVDLGCPSP 2477 +GE W + L C Q C+ + + GCP P Sbjct: 2678 -----LVGEELKWPGVSFLLGNCSQCVCEKGELLCQPG-GCPLP 2715 Score = 34.3 bits (77), Expect = 1.9 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 7/78 (8%) Query: 1410 WRYDACASPCFQTCRDPRAAS-CRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDCVEPAV 1468 + + AC SPC C + C+D+P C P C P+ L E C+ E+C Sbjct: 4427 FEFHACGSPCAGLCATHLSHQLCQDLP---PCQPGCYCPKGLLEQAGGCIPPEEC---NC 4480 Query: 1469 WVPTEALGNETLPPSQGL 1486 W + A TL P L Sbjct: 4481 WHTSAAGAGMTLAPGDRL 4498 Score = 32.7 bits (73), Expect = 5.4 Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 26/118 (22%) Query: 1799 MSLESTRPSQLL----SGLPPDTSLPLAKVGTSAPVAT----PGPKASV----------I 1840 ++L S +P QLL GL P + ++P T PGP + V Sbjct: 2285 LALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVT 2344 Query: 1841 TTPL-QPQATTLPAQTLS-------PVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1890 TTP+ Q +A TLP + PV P TPA + A P G P +LG Sbjct: 2345 TTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLG 2402 Score = 32.7 bits (73), Expect = 5.4 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 14/88 (15%) Query: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHR-RHSALCIPE 2430 C + C C P++CQD G + CQ GC + G L + LC+P Sbjct: 3529 CGGGQSLHPCGQPC--PRSCQDLSPGSV----CQPGSVGCQPTCGCPLGQLSQDGLCVPP 3582 Query: 2431 AKCAC---TDSMGVP----RALGETWNS 2451 A C C +MG+P R+ G ++S Sbjct: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFSS 3610 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 512 bits (1318), Expect = e-144 Identities = 350/1152 (30%), Positives = 520/1152 (45%), Gaps = 87/1152 (7%) Query: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210 C WG H TFD Y SG +Y + +FS+Q+ P S S Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGAS 104 Query: 211 LFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ---QLAGYVIVRHQSAFTLAWDGASA 267 + V E I + K++ G+ + LP+ ++ Q V + + + W S Sbjct: 105 VVTVSEAIISV-KDI---GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSH 159 Query: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP--T 325 + + + + +G GLCGN + ++ V+ GK + H + PG T Sbjct: 160 LMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-----HKFAALQKLDDPGEICT 214 Query: 326 TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM--GD 383 +P Q + C LL C VS PF SC +D+ + G Sbjct: 215 FQDIPSTHVRQAQHARI------CTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGP 266 Query: 384 VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC-HPRAS 442 + C L+EY+R C+ G+P++ WR+ C+V Y EC + C +C +P+ S Sbjct: 267 QNSSCATLSEYSRQCSMVGQPVRRWRSP-GLCSVGQCPANQVYQECGSACVKTCSNPQHS 325 Query: 443 CVDSEIACVDGCYCPNGLIFEDGG----CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT 498 C S C GC+CP G + D CV +CPC HG +Y PG V C TC CT Sbjct: 326 CSSS---CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCT 382 Query: 499 SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS---SGTFTVTLQNA 555 G+W C+ CP CS+ G TTFD R Y F TC YIL +S G + Sbjct: 383 LGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKS 442 Query: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF 615 G++ + +V + QD ++ ++Q V + K +P Y + R +S Sbjct: 443 --GVSHSETSLVAVVYLSRQD---KIVISQDEVVTNNGEAKWLP-YKTRNITVFRQTSTH 496 Query: 616 LRVRTNVGVRVLYD-REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674 L++ T+ G+ ++ R + Y+ V ++ T GLCG FNG+T DDF + +G+ E T Sbjct: 497 LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556 Query: 675 LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPY 732 LF +SW+ + P DPC + + CS+L TG +F C A ++P P+ Sbjct: 557 LFVDSWRAGNC--PAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPF 614 Query: 733 FEQCRRDACRCGQ--PCLCATLAHYAHLCRRHGLPV-DFRARLPACALSCEASKEYSPCV 789 +++C AC + P +CA L Y H C G+ + +R+ + C + C + +S Sbjct: 615 YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674 Query: 790 APCGRTCQDLASPEACGVDGGDDLSRDEC------VEGCACPPDTYLDTQADLCVPRNQC 843 C RTC L+ EC V+GC CP TYL+ + + CV + QC Sbjct: 675 QACERTCLSLSDRAT------------ECHHSAVPVDGCNCPDGTYLNQKGE-CVRKAQC 721 Query: 844 SCHFQGVDYPPGDSDIPSLG-HCHCKDGVMSCDSRAPA--AACPAGQVFVNCSDLHTD-L 899 C +G + + G CHC +G +SC R A+C A + F +CS + Sbjct: 722 PCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKF 781 Query: 900 ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGD 958 + TC Q L C GC C +GL + D C PEECPC + G Y G Sbjct: 782 GAACAPTC-QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840 Query: 959 QVMSPCHTCVCQRGSFQCTLHP-CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 1017 ++ + C TC C RG + C C STCT YG+ H TFDG F F G C+ L Sbjct: 841 ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900 Query: 1018 VS-----FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHT 1072 V+ F ++ ENV C +SG+ C + I I +G +V D + + E + V Sbjct: 901 VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEE-PHVQLGVTP 959 Query: 1073 WRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1131 + + P + +TL+W++ T+ ++ Q L GLCGNF+ ++ T Sbjct: 960 GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019 Query: 1132 ELTNPQEFGSSWAAVE-CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVT 1190 ++ E +SW C D D C LN R +A+++CS++ S+ F CH V Sbjct: 1020 VASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHL 1079 Query: 1191 WFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVL- 1249 +Y C+ D CGC GGDCEC C +V+AYA C GV VDWRTP CP C F+N Sbjct: 1080 PYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQ 1139 Query: 1250 -GKGPYQLSSLA 1260 G G YQ + A Sbjct: 1140 DGHGEYQYTQEA 1151 Score = 226 bits (577), Expect = 2e-58 Identities = 218/864 (25%), Positives = 335/864 (38%), Gaps = 197/864 (22%) Query: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210 C G V TFD Y G +Y L+ + + V++ + G S S Sbjct: 397 CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSHSETSLVAV 454 Query: 211 LFFVGEQEIHLAKE--VTHGGMRVQLPHV--------MGSARLQQLAGY---VIVRHQSA 257 ++ + +I ++++ VT+ G LP+ S LQ + ++V+ + Sbjct: 455 VYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI 514 Query: 258 FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE-- 315 F Y+ + P+ G T GLCGN N D DD TS G FV SW+ Sbjct: 515 FQ--------AYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGN 566 Query: 316 --QAPNQPPGPTTSSLPRPPCLQQNPGTMQG---VYEQCEALLRPP-------FDACHAY 363 A + P + S C + + + V+E+C A + P + AC+ Y Sbjct: 567 CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN-Y 625 Query: 364 VSPLPF-----------------------------TASCTSDL------------CQSMG 382 P T CT + C S+ Sbjct: 626 EETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLS 685 Query: 383 DVATWCRALAEYARAC-----------------AQAGRPLQGWR-------TQLRQCTVH 418 D AT C A C AQ L+G++ T + T H Sbjct: 686 DRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCH 745 Query: 419 C---------KEKAF--------TYNECIACCP----ASCHPRASCVDSEIACVD----- 452 C + + F T+ C A+C P + + +ACV Sbjct: 746 CINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEP 805 Query: 453 GCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAV-CP 510 GC C GL DG CV P ECPCEF G YP G+ + DC TC+C+ G+W C CP Sbjct: 806 GCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCP 865 Query: 511 AECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQDGAC 565 + C++ G+ H TFDG+R+ F C+YILA + S TF + +N CG N C Sbjct: 866 STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTC 924 Query: 566 VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVR 625 +++ + L V L + ++ + T A + V + + + Sbjct: 925 SRAIKIFLGG---LSVVLADRNYTVTGEEPHVQLGVTPGALSL----VVDISIPGRYNLT 977 Query: 626 VLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA 685 ++++R + + +++ + + GLCG FNGN +DDF + S+ NSWK Sbjct: 978 LIWNRH-MTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL 1036 Query: 686 CSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ 745 C + DPC ++ S++ + CSV+ + FA C + + +PY+E C RDAC C Sbjct: 1037 CGDV--SFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDS 1094 Query: 746 ----PCLCATLAHYAHLCRRHGLPVDFRARLPA-CALSC--------------------E 780 CLC +A YA C G+ VD+R PA C + C Sbjct: 1095 GGDCECLCDAVAAYAQACLDKGVCVDWRT--PAFCPIYCGFYNTHTQDGHGEYQYTQEAN 1152 Query: 781 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA-CPPDTYLDTQADLCVP 839 + Y PC+ P + P++ V G + +EGC C D Y D + +CVP Sbjct: 1153 CTWHYQPCLCP--------SQPQS--VPGSN-------IEGCYNCSQDEYFDHEEGVCVP 1195 Query: 840 RNQCSCHFQGVDYPPGDSDIPSLG 863 C PP +P+ G Sbjct: 1196 -----CMPPTTPQPPTTPQLPTTG 1214 Score = 118 bits (295), Expect = 1e-25 Identities = 114/402 (28%), Positives = 172/402 (42%), Gaps = 43/402 (10%) Query: 506 TAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDG 563 TA +CS G HF+TFD Y F TC YI A + TF+V L+ P G Sbjct: 38 TAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDG----- 92 Query: 564 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRL--SSVFLRVRTN 621 S+S I+ + VT+++A + + D I PYT + +I S + + Sbjct: 93 ----SISRIIVELGASVVTVSEA-IISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLE 147 Query: 622 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 681 + + V++ + L + V+++++ GLCG F+G ++F+S G P F K Sbjct: 148 LELEVVWGPDS-HLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFAALQK 205 Query: 682 TLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741 P + D H++ A ++ + C+ L + CS +S P+ C+ D Sbjct: 206 ---LDDPGEICTFQDIPSTHVRQAQHA-RICTQLLTLVAPECS--VSKEPFVLSCQADVA 259 Query: 742 RCGQP----CLCATLAHYAHLCRRHGLPVDFRARLPA-CAL-SCEASKEYSPCVAPCGRT 795 QP CATL+ Y+ C G PV R R P C++ C A++ Y C + C +T Sbjct: 260 AAPQPGPQNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKT 318 Query: 796 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQAD--LCVPRNQCSCHFQGVDYP 853 C + +C C GC CP T L+ ++ CVP QC C G Y Sbjct: 319 CSN--PQHSCS---------SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367 Query: 854 PGDSDIPSLGHCHCKDGVMSCDSR-APAAACPAGQVFVNCSD 894 PG+ I + C C G C R P G FV D Sbjct: 368 PGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFD 409 Score = 111 bits (277), Expect = 1e-23 Identities = 117/426 (27%), Positives = 164/426 (38%), Gaps = 67/426 (15%) Query: 104 KCAPSYLFSCFNG------GECVHPAFCDCRRFNATGP---------------RCQMVYN 142 KC P + C G G+CV P C C + P R + Sbjct: 802 KCEPGCV--CAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQ 859 Query: 143 AGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQC 198 G S C +G+ HV TFDG + G Y L G ++ + +F I N C Sbjct: 860 QGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQ-PTFKILTEN-VIC 917 Query: 199 GSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAF 258 G+S TCSRA+ +F G + + T G + PHV L+ V + + Sbjct: 918 GNSGVTCSRAIKIFLGGLSVVLADRNYTVTG---EEPHVQLGVTPGALSLVVDISIPGRY 974 Query: 259 --TLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQ 316 TL W+ + I+++ GLCGN N + KDD T S + +E V+SW+E Sbjct: 975 NLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKES 1034 Query: 317 APNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD 376 P S PC N +C + F CH+ V LP+ +C D Sbjct: 1035 -----PLCGDVSFVTDPC-SLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRD 1088 Query: 377 L--CQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC---------KEKAFT 425 C S GD C A+A YA+AC G + WRT C ++C + Sbjct: 1089 ACGCDSGGDCECLCDAVAAYAQACLDKGVCVD-WRTP-AFCPIYCGFYNTHTQDGHGEYQ 1146 Query: 426 YNECIACC----PASCHPRASCVDSEIACVDGCY-CPNGLIF--EDGGCVAPAECPCEFH 478 Y + C P C + V + ++GCY C F E+G CV PC Sbjct: 1147 YTQEANCTWHYQPCLCPSQPQSVPG--SNIEGCYNCSQDEYFDHEEGVCV-----PCMPP 1199 Query: 479 GTLYPP 484 T PP Sbjct: 1200 TTPQPP 1205 Score = 94.4 bits (233), Expect = 2e-18 Identities = 146/606 (24%), Positives = 231/606 (38%), Gaps = 63/606 (10%) Query: 1483 SQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQ 1542 SQ + S + S S + TH P +TP + T NP T T PV + T+ + Sbjct: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTN-SATSSR 1568 Query: 1543 QPLELTASQLPAGPTESPASKGVTASLLAIPHT-PESSSLPVALQTPTPGMVSGAMETTR 1601 P T P G + ++ +TA+ T P S L T P + + + Sbjct: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628 Query: 1602 VTVIFAGSPNITVSS--RSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPV 1659 TVI + S+ S P P T T++ GS T P +LT S +S+ + Sbjct: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPT---TLKATGS---THTAPTMTLTTSGTSQAL 1682 Query: 1660 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAEQV 1718 +S +++ TS SH + A S T + P PT S +P +T +GT+ + Sbjct: 1683 SSLNT-AKTSTSLHSHTSSTHHAEATSTSTTNITPNPT---STGTPPMTVTTSGTSQSR- 1737 Query: 1719 PVSPLATRSLEIVLSTEKGEAGHSQPMG-SPASPQPHPLPSAPPRPAQHTTMATRSPALP 1777 S +T L + H + S S P+ + P HTT AT S Sbjct: 1738 --SSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795 Query: 1778 PET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP 1833 P T P + ++T + AT F + +T P+ P T+LP S + TP Sbjct: 1796 PFTTHSPPTGTTPISSTGPVTATSFQT-TTTYPTP----SHPHTTLPTHVPSFSTSLVTP 1850 Query: 1834 GPKASVITTPLQPQAT----TLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLL 1889 +I T Q + ++P T+ P P T A H + P +GT+ Sbjct: 1851 STHTVIIPTHTQMATSASIHSMPTGTIPP--PTTIKATGSTHTAPPMTPTTSGTSQSPSS 1908 Query: 1890 GATLPTSGVLPVAEGT--------ASMVSVVPRKSTTGKVAILSKQVS-----LPTSM-- 1934 +T TS LP + S ++ P+ ++TG ++ S LPT Sbjct: 1909 FSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT 1968 Query: 1935 ----YGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPV---PTSYALSRVSARTAPQ 1987 GS+ T ATS T P Q T LP P S +L S T Sbjct: 1969 HSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ--TTLPTHVPPFSTSLVTPSTHTV-- 2024 Query: 1988 DSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSI-VEGLAEALATTTEAN 2046 ++ Q+A + + P P S +AP +++ G ++ ++ + A Sbjct: 2025 --IITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTAT 2082 Query: 2047 TSTTCV 2052 S++ + Sbjct: 2083 ASSSFI 2088 Score = 92.8 bits (229), Expect = 4e-18 Identities = 128/530 (24%), Positives = 195/530 (36%), Gaps = 74/530 (13%) Query: 2044 EANTSTTCVPIAEQDCVRHICLEGQ-LIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCC 2102 + + + TCVP+ + CV H + + + Q C RC + G C Sbjct: 344 DLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC-------RCTL--------GRWVC 388 Query: 2103 PLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP---DEMLTVHVLDCKSANLGH 2159 C CS+ TFD YIL QSP ++ + V D + + H Sbjct: 389 TERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSH 446 Query: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRI--EDTGHMYMILT 2217 +V L+ ++ I + + VT + + W P + + + H+ M + Sbjct: 447 SETSLVAVVYLSRQD---KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATS 502 Query: 2218 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2277 + L V + Q GLCG +GD +D T G G A + F+ Sbjct: 503 FGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTA---SLFV 559 Query: 2278 DSWQV------------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPP 2325 DSW+ P S++ + + CA T CS LR + F CH V P Sbjct: 560 DSWRAGNCPAALERETDPCSMSQLNKV------CAETHCSMLLR--TGTVFERCHATVNP 611 Query: 2326 ESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRS-DYCPFLCSSDSTYQ 2379 F + + ++ C AL YV C V + WR S D C C+ ++T+ Sbjct: 612 APFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFS 671 Query: 2380 ACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSM 2439 ACE +TC + H V +GC C +GT L+++ C+ +A+C C Sbjct: 672 YNSQACE--RTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGE--CVRKAQCPCI-LE 726 Query: 2440 GVPRALGE---TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRP-ESCLRFGE---VALLL 2492 G L E N C + P C +P+ +SC + E A Sbjct: 727 GYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786 Query: 2493 PTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD 2542 PT G CV T CE P C L + + C P C C+ Sbjct: 787 PTCQMLATGVACV--PTKCE---PGCVCAEGLYEN-ADGQCVPPEECPCE 830 Score = 92.0 bits (227), Expect = 8e-18 Identities = 174/731 (23%), Positives = 248/731 (33%), Gaps = 102/731 (13%) Query: 1408 CEWRYDACASPCF-QTCRDPRAASCRDVPRGRS-------CVPVCPTPQVLDEVTQRCVY 1459 C W Y C P Q+ C + + CVP C P T + Sbjct: 1153 CTWHYQPCLCPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP-CMPPTTPQPPTTPQLP 1211 Query: 1460 LEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRP----ALTPAAP 1515 VW T L S G P+PS S +P +PT P LT + P Sbjct: 1212 TTGSRPTQVWPMTGTSTTIGLLSSTG-PSPS------SNHTPASPTQTPLLPATLTSSKP 1264 Query: 1516 LTTALNPP-VTATEEPVVSPG--PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572 ++ PP T P + G PT T + T +Q T S AS T++ + Sbjct: 1265 TASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQST 1324 Query: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSR---SPPAPRFPLMTK 1629 T + P T S E T P T +S + P P P Sbjct: 1325 TRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPT 1384 Query: 1630 AVTVRGHGSLPVRTTPPQPSLTASP--SSRPVASPGAISRS--------PTSSGSH---- 1675 A + TTP P T SP + PV S G ++ + PT S Sbjct: 1385 ATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLP 1444 Query: 1676 -------KAVLTPAVTKVISRTGVPQPTQAQSASSPS------TPLTVAGTAAEQVPVSP 1722 +++TP+ VI+ T T A + S+P+ T L G+ P++P Sbjct: 1445 THVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITP 1504 Query: 1723 L--ATRSLEIVLSTEKGEAG-HS------QPMGSPASP---QPHPLPSAPPRPAQHTTMA 1770 T ST K HS P +P S P+P + P HT A Sbjct: 1505 TTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSA 1564 Query: 1771 TRSPALPPET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGT 1826 T S PP T P +S ++T + AT F + +T P+ P T+LP Sbjct: 1565 TSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT-TTTYPTP----SHPQTTLPTHVPPF 1619 Query: 1827 SAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAP----PAAG 1882 S + T P + TP Q T + P P +A TH AP +G Sbjct: 1620 STSLVT--PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSG 1677 Query: 1883 TAPGLLLGATLPTSGVLPV-------AEGTA-SMVSVVPRKSTTG--KVAILSKQVSLPT 1932 T+ L T TS L AE T+ S ++ P ++TG + + + S Sbjct: 1678 TSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSR 1737 Query: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVP--TSYALSRVSARTAPQDSM 1990 S + +A+ T + H T PE T P TS A T S Sbjct: 1738 SSFSTAK------TSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSS 1791 Query: 1991 LVLLPQLAEAHGTSAGPHLAAEPVD----EATTEPSGRSAPALSIVEGLAEALATTTEAN 2046 + P + T P + PV + TT S P ++ + + + Sbjct: 1792 RLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS 1851 Query: 2047 TSTTCVPIAEQ 2057 T T +P Q Sbjct: 1852 THTVIIPTHTQ 1862 Score = 76.6 bits (187), Expect = 3e-13 Identities = 68/270 (25%), Positives = 113/270 (41%), Gaps = 23/270 (8%) Query: 980 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKF 1039 P C+ +G H+ TFD +DF G C ++ +T +F + G I R Sbjct: 40 PDKGQCSTWGAGHFSTFDHHVYDFSGTCN-YIFAATCKDAFPTFSVQLRRGPDGSISRII 98 Query: 1040 IS-----INVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQ 1094 + + V ++I D P + + ++ + + + + ++W Sbjct: 99 VELGASVVTVSEAIISVKDIGVISLP--YTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156 Query: 1095 RTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDP 1154 + + V ++ GQ+ GLCGNFD K NE + E + P +F AA++ D DP Sbjct: 157 DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKF----AALQKLD--DP 209 Query: 1155 RDMCVLNPL-----REPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209 ++C + R+ + C+ LL+ V C V F +C D Q G Sbjct: 210 GEICTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQ 267 Query: 1210 ECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1238 CA++S Y+ QC G V WR+P LC Sbjct: 268 NSSCATLSEYSRQCSMVGQPVRRWRSPGLC 297 Score = 75.1 bits (183), Expect = 9e-13 Identities = 124/521 (23%), Positives = 202/521 (38%), Gaps = 76/521 (14%) Query: 1479 TLPPSQGLPTPSDEEPQLSQESPRTPT-----HRPALTPAAPLTTALNPPVTATEEPVVS 1533 T+PP PT P TPT P+ A +T+L ++T P V+ Sbjct: 1876 TIPP----PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931 Query: 1534 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1593 P T T + T ++ P T S +S + H+P + S P + P M Sbjct: 1932 PTST-TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT--HSPPTGSSPFSSTGP---MT 1985 Query: 1594 SGAMETTRVTVIFAGSPNITVSSRSPPAPR-----------FPLMTKAVTVRGHGSLPVR 1642 + + +TT T P T+ + PP T+ T S P Sbjct: 1986 ATSFQTT-TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044 Query: 1643 TTPPQPSLTASPSSRPVASPGAISRSPTS-SGSHKAVLTPAVTKVISRTGVPQPTQAQSA 1701 T PP +L A+ S+ A P ++ S TS + S + T + + + S + +PQ + S+ Sbjct: 2045 TVPPPTTLKATGSTH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNS---SS 2100 Query: 1702 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH-PLPSAP 1760 PS+P+T Q+P LS+ + + S SP P P + Sbjct: 2101 RPPSSPITT------QLP-----------HLSSATTPVSTTNQLSSSFSPSPSAPSTVSS 2143 Query: 1761 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1820 P+ H++ T SP S+ T++ ++A + S+ LS P S+ Sbjct: 2144 YVPSSHSSPQTSSP----------SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193 Query: 1821 LAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPA 1880 + + S+P A+ +A++ T P TLS +LP + ++ P +H+A Sbjct: 2194 ASPLFPSSPAASTTIRATLPHTISSP-------FTLSALLPISTVTVSPT-PSSHLASST 2245 Query: 1881 AGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTS---MYGS 1937 A+ T+ T+ S+ R T+G V++ S +PTS + Sbjct: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305 Query: 1938 AEGGPTELTPATSHPLTPLVAE---PEGAQAGT-ALPVPTS 1974 GPT L+P T + L A P A + P PTS Sbjct: 2306 RHPGPT-LSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345 Score = 55.1 bits (131), Expect = 1e-06 Identities = 70/288 (24%), Positives = 107/288 (37%), Gaps = 47/288 (16%) Query: 2191 DLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGL 2247 D+ + P + G +I G ++ ++++ W S LM++ K Q GL Sbjct: 117 DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYM-GQMCGL 175 Query: 2248 CGICDGDAANDLTLKDG--------SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC 2299 CG DG N+ ++G + + +DP +PS T V Q + Sbjct: 176 CGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS--THVRQAQH----- 228 Query: 2300 ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMC 2353 C+ L +V A V E F D QP C L+ Y C Sbjct: 229 -ARICTQLLTLV------APECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQC 281 Query: 2354 HKFHVCI-EWRRSDYCPF-LCSSDSTYQACVTACEPPKTCQDGILGPLDPEH--CQVLGE 2409 + WR C C ++ YQ C +AC KTC +P+H Sbjct: 282 SMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC--VKTCS-------NPQHSCSSSCTF 332 Query: 2410 GCVCSEGTILH-RRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2456 GC C EGT+L+ ++ C+P +C C G A GE ++ C Sbjct: 333 GCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAPGEVTIAACQTC 379 Score = 51.2 bits (121), Expect = 1e-05 Identities = 84/384 (21%), Positives = 129/384 (33%), Gaps = 92/384 (23%) Query: 2047 TSTTCVPI-AEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLW 2105 T CVP E CV C EG L Q P P C G++ G + Sbjct: 794 TGVACVPTKCEPGCV---CAEG-LYENADGQCVPPEECP--CEFSGVSYPGGAELHTDCR 847 Query: 2106 ECACR---------------CSIFPDLSFVTFDGSHVALFKEAIYIL---------SQSP 2141 C+C C+++ + +TFDG YIL SQ Sbjct: 848 TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907 Query: 2142 DEMLTVHVL------DCKSANLGHLNWPPFCLVMLNMT------HLAHQVTIDRFNRKVT 2189 ++LT +V+ C A L L N T H+ VT + V Sbjct: 908 FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD 967 Query: 2190 VDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCG 2249 + + RY + HM +++ ++ S+ GLCG Sbjct: 968 ISIP------GRYNLTLIWNRHM------------------TILIRIARASQDPLCGLCG 1003 Query: 2250 ICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------A 2300 +G+ +D + V A ++SW+ G F D C A Sbjct: 1004 NFNGNMKDDFETRSRYV---ASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWA 1057 Query: 2301 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCH 2354 CS +++++TF+ CH V + E +RD C A+ Y C Sbjct: 1058 ERKCS----VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACL 1113 Query: 2355 KFHVCIEWRRSDYCPFLCSSDSTY 2378 VC++WR +CP C +T+ Sbjct: 1114 DKGVCVDWRTPAFCPIYCGFYNTH 1137 Score = 33.9 bits (76), Expect = 2.4 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%) Query: 2859 VNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFC---ATNATWVPYTVQE 2915 V + C+G C SA+ +N C CCR + + ++L C +T + T+Q Sbjct: 2367 VTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVLTLQV 2426 Query: 2916 PTDCAC 2921 + C C Sbjct: 2427 FSHCVC 2432 >gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo sapiens] Length = 2134 Score = 476 bits (1226), Expect = e-133 Identities = 288/932 (30%), Positives = 447/932 (47%), Gaps = 65/932 (6%) Query: 347 EQCEALLRPPFDACHAYVS-PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGR-P 404 + C ++ F+ C + + C + CQ+ +T C +E +R CA G Sbjct: 687 QHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTST-CDTYSELSRLCASDGPGT 745 Query: 405 LQGWRTQLRQC--TVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIF 462 + WR+ T C E+ Y EC PA+C A DSE CV GC CP G + Sbjct: 746 FESWRSDSDVVCETQRCPEQHI-YKECGPSNPATCSNVAPFQDSE--CVSGCTCPEGYLL 802 Query: 463 ED----GGCVAPAECPCEFHGTLYPPGSVVKEDCNT-CTCTSGKWECSTAVCPAECSVTG 517 +D G CV AECPCE GT+Y PG V + C + CTC KW C+ A+CP C V G Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEG 862 Query: 518 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 577 TTFDG +Y FP C ++ + ++++++ PC Q G C+ SV+++L+ Sbjct: 863 S-SLTTFDGVKYNFPGNCHFLAVHNED---WSISVELRPCPSGQTGTCLNSVTLLLNSSV 918 Query: 578 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRV-LYDREGLRLY 636 + + + D+ + Y D +I SS +L+V T V++ + ++LY Sbjct: 919 PVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLY 978 Query: 637 LQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLD 696 + + DTVGLCG++N +DDF+S + E T Q F NSW+ +S G+P Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSC----PKGNP-S 1033 Query: 697 PCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDACRC--GQPCLCATL 752 C + ++ ++ + C +L A C ++P PY E+C++ C C Q CLC L Sbjct: 1034 SC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 1092 Query: 753 AHYAHLC-RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE-ACGVDGG 810 +Y C + V +R L C SC + + V C +C+ L+ + +C V+ Sbjct: 1093 GNYVKACAEKETYIVGWRTGL--CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVE-- 1148 Query: 811 DDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDG 870 D V+GC CP Y + + + CV ++QC C+ PG C C+DG Sbjct: 1149 -----DVPVDGCTCPDAMYQNNEGN-CVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202 Query: 871 VMSCDSRAPAAA--CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG-PCLSGCA 927 ++ C C G +V+CSD + RTC + N+ V PC GC Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSD--PKAQRRTNRTCSTR--NIPVFDENLPCKRGCF 1258 Query: 928 CPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 986 CP+G++R+ C P +CPC++ G+EY G C+ C C +GS+ CT + C + C Sbjct: 1259 CPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICH 1318 Query: 987 AYGDRHYRTFDGLPFDFVGACKVHLVKST---SDVSFSVIVENVNCYSSGMICRKFISIN 1043 YG+ H RTFDG + F G C+ ++ + +F ++ E+V C G+ C + I + Sbjct: 1319 IYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCSRKIIVA 1378 Query: 1044 VGNSLIVFDDDSGNPSPESFLDDKQ--------EVHTWRVGFFTLVHFPQEHITLLWDQR 1095 + IV D G + + K+ +HT VG + ++ F Q I ++WD+ Sbjct: 1379 FQDQNIVLQD--GKVTAVKSTESKKCELNANAYSIHT--VGLYLILKF-QNGIIVIWDKN 1433 Query: 1096 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDP 1154 T + V P W G++ GLCGN + ++ T + + EFG+SW + EC DT+ Sbjct: 1434 TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ 1493 Query: 1155 RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCA 1214 C NP + +A ++C IL F CH VD + ++ C+ + C C G FC Sbjct: 1494 TFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1553 Query: 1215 SVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246 +V+ YA C GV V WR P LCP CD++N Sbjct: 1554 AVAMYAEACSAVGVCVSWRKPNLCPVYCDYYN 1585 Score = 211 bits (537), Expect = 8e-54 Identities = 140/455 (30%), Positives = 201/455 (44%), Gaps = 41/455 (9%) Query: 445 DSEIACVDGCYCPNGLIFEDGG-CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 503 D + C GC+CP G++ G CV P +CPC F G Y GSV CN CTC G W Sbjct: 1248 DENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWS 1307 Query: 504 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLN 560 C+ C C + G+ H TFDG+ Y+F CQY + +GTF + ++ PC Sbjct: 1308 CTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCC-- 1365 Query: 561 QDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSVFLRVR 619 +DG ++ QD Q + Q G V + +A+ I + ++L ++ Sbjct: 1366 EDGLTCSRKIIVAFQD---QNIVLQDGKVTAVKSTESKKCELNANAYSIHTVG-LYLILK 1421 Query: 620 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 679 G+ V++D+ RL + +D W GLCG NG+ +DDF + S FGNS Sbjct: 1422 FQNGIIVIWDKN-TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNS 1480 Query: 680 WKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 739 WKT CS V+ + PCD + +++V+ C +L F C + P Y + C + Sbjct: 1481 WKTSQECSDTVAQT--FPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEE 1538 Query: 740 ACRCGQPC----LCATLAHYAHLCRRHGLPVDFRARLPACALSC-------EASKEYSPC 788 AC C C +A YA C G+ V +R + C + C E Y PC Sbjct: 1539 ACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWR-KPNLCPVYCDYYNAPGECRWHYEPC 1597 Query: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPPDT-YLDTQADLCVPRNQCSC 845 +TC+D G S +EGC CP YLD CV ++CSC Sbjct: 1598 GTVTAKTCKDQLV--------GQKFS--SLLEGCYAKCPDSAPYLDENTMKCVSLSECSC 1647 Query: 846 HFQGVDYPPGDSDIPSLGH-CHCKDGVMSCDSRAP 879 + V P G + G C+C G + C AP Sbjct: 1648 FYNDV-IPAGGVIEDNCGRTCYCIAGQLECSETAP 1681 Score = 132 bits (333), Expect = 4e-30 Identities = 107/380 (28%), Positives = 167/380 (43%), Gaps = 34/380 (8%) Query: 146 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYT 204 E +IC +G+ HV TFDG Y G Y+ + + E +F I + P C T Sbjct: 1312 ECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDG-LT 1370 Query: 205 CSRAVSLFFVGEQEIHLAKEVTH----GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTL 260 CSR + + F + + +VT + +L + + + Y+I++ Q+ + Sbjct: 1371 CSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELN--ANAYSIHTVGLYLILKFQNGIIV 1428 Query: 261 AWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQ 320 WD + + + + P G GLCGNNN D KDD T + +EF +SW+ +Q Sbjct: 1429 IWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQ 1485 Query: 321 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LC 378 T + PC NP +CE L F CH V P + C + C Sbjct: 1486 ECSDTVAQ--TFPC-DSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACAC 1542 Query: 379 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIAC 432 G +C A+A YA AC+ G WR + C V+C E + Y C Sbjct: 1543 DMEGKYLGFCTAVAMYAEACSAVG-VCVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTV 1600 Query: 433 CPASCHPRASCVDSEI-ACVDGCY--CPNGLIFEDGG---CVAPAECPCEFHGTLYPPGS 486 +C + V + + ++GCY CP+ + D CV+ +EC C F+ + P G Sbjct: 1601 TAKTC--KDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSC-FYNDVIPAGG 1657 Query: 487 VVKEDC-NTCTCTSGKWECS 505 V++++C TC C +G+ ECS Sbjct: 1658 VIEDNCGRTCYCIAGQLECS 1677 Score = 111 bits (277), Expect = 1e-23 Identities = 114/451 (25%), Positives = 164/451 (36%), Gaps = 83/451 (18%) Query: 105 CAPSYLFSCFNG-GECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRA--------W- 154 C YL G+CV A C C VY G R+ C + W Sbjct: 796 CPEGYLLDDIGEKGKCVLKAECPCESSGT-------VYQPGEVREGPCGSQCTCQDAKWS 848 Query: 155 -------GQHHVE-----TFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 202 G+ VE TFDG+ Y G + V + +SI V P Sbjct: 849 CTEALCPGRCKVEGSSLTTFDGVKYNFPGNCHFLAV-----HNEDWSISVELRPCPSGQT 903 Query: 203 YTCSRAVSLFF-----VGEQEIHLAKEVTHGGMRVQ-------LPHVMGSARLQQLAGYV 250 TC +V+L V + + VT+ +R Q + S+ Q+ Y Sbjct: 904 GTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYF 963 Query: 251 IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFV 310 V+ Q +Y+ M P T GLCG+ N +DD ++S L F Sbjct: 964 HVKLQIQIVPVMQ----LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFA 1019 Query: 311 HSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALL--RPPFDACHA 362 +SW+ + C + NP + + ++ C LL P +CH Sbjct: 1020 NSWEMMS----------------CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHP 1063 Query: 363 YVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE- 421 V+P P+ C C C L Y +ACA+ + GWRT L C C Sbjct: 1064 IVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSG 1121 Query: 422 KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLI-FEDGGCVAPAECPCEF 477 F YN + C +SC R D E VDGC CP+ + +G CV ++C C Sbjct: 1122 LVFKYN--VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 1179 Query: 478 HGTLYPPGSVVKEDCNTCTCTSGKWECSTAV 508 + + PG ++ D N C C G C + Sbjct: 1180 NDEVMQPGKLIHIDDNKCVCRDGILLCQIPI 1210 Score = 75.5 bits (184), Expect = 7e-13 Identities = 56/207 (27%), Positives = 89/207 (42%), Gaps = 26/207 (12%) Query: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS---CATT 2302 GLCG +GD +D T + SV GA + F +SW+ + F DS C Sbjct: 1450 GLCGNNNGDLKDDFTTRYSSVASGALE---FGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1506 Query: 2303 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-------KYVQQPCVALTVYVAMCHK 2355 C ++ + TF CH V P ++ ++ I + KY+ C A+ +Y C Sbjct: 1507 AVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF-CTAVAMYAEACSA 1564 Query: 2356 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEP-----PKTCQDGILGPLDPEHCQVLGEG 2410 VC+ WR+ + CP C + C EP KTC+D ++G + L EG Sbjct: 1565 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG----QKFSSLLEG 1620 Query: 2411 CV--CSEGTILHRRHSALCIPEAKCAC 2435 C C + ++ C+ ++C+C Sbjct: 1621 CYAKCPDSAPYLDENTMKCVSLSECSC 1647 Score = 67.4 bits (163), Expect = 2e-10 Identities = 122/529 (23%), Positives = 187/529 (35%), Gaps = 80/529 (15%) Query: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCP-TPQVLDEVTQRCVYLEDC--- 1463 C W Y+ C + +TC+D + + C CP + LDE T +CV L +C Sbjct: 1590 CRWHYEPCGTVTAKTCKD-QLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1648 Query: 1464 ---VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTAL 1520 V PA V + G T G S+ P S + T T L+ A +T Sbjct: 1649 YNDVIPAGGVIEDNCG-RTCYCIAGQLECSETAPTNSTFAVSTTTATTILSTGAAITLVT 1707 Query: 1521 NPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSS 1580 P TA P ++ ++TT GP P + G+T + + I T ++ Sbjct: 1708 GGPSTAASIPAITTSSSETT----------GTTLGPLTEPFTTGITETSVPIISTSGNAG 1757 Query: 1581 LPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1640 + + G A T V G+ + S R+ PR T AV G GS Sbjct: 1758 MTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA-GTPRVSGATPAV---GGGS-- 1811 Query: 1641 VRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS 1700 TP + A+ S S G+I+ SP +S A + S++G P+ Sbjct: 1812 ---TPGEAGPGATVSGSTGVSAGSITASPGAS---------ATSSESSKSGTTGPSVGGK 1859 Query: 1701 ASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1760 + S+ T + + S +T + ++ + G SP P P +P Sbjct: 1860 TGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTG-----SSPPGKLTRPSPGSP 1914 Query: 1761 PRPAQHTT------------------MATRSPALPPETPAAASLSTATDG---------- 1792 + TT + + ++ T A + + T G Sbjct: 1915 GHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTA 1974 Query: 1793 LAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVA----TPGPKASVITTPLQPQA 1848 ++ TP +S +T P S P + + G S T A + TP A Sbjct: 1975 VSGTPVVSPGAT-PGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAA 2033 Query: 1849 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSG 1897 +T T SPV T AA A + P GT G G + TSG Sbjct: 2034 ST----TSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKI-TSG 2077 Score = 49.7 bits (117), Expect = 4e-05 Identities = 91/424 (21%), Positives = 152/424 (35%), Gaps = 59/424 (13%) Query: 2047 TSTTCVPIAEQDCVRHI-CLEGQLIR-VNQSQHCPQGAAPPRCGILGLAVRVG------- 2097 T + P + +CV C EG L+ + + C A P C G + G Sbjct: 778 TCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP-CESSGTVYQPGEVREGPC 836 Query: 2098 GDRC--------CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHV 2149 G +C C C RC + S TFDG ++ + D ++V + Sbjct: 837 GSQCTCQDAKWSCTEALCPGRCKV-EGSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVEL 895 Query: 2150 LDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR--FNRKVTVDLQPVWPPVSRYGFRIE 2207 C S G CL + + L V +D+ FN TV + Y +I+ Sbjct: 896 RPCPSGQTGT------CLNSVTLL-LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQ 948 Query: 2208 --DTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLK 2262 + Y+ + +QIQ + L V GLCG + A +D Sbjct: 949 IFNASSSYLQVETYFHVKLQIQIVPVMQLY-VSMPPNQFTDTVGLCGSYNNKAEDDFMSS 1007 Query: 2263 DGSVVGGAEDPAPFLDSWQV-------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT 2315 + ++ F +SW++ PSS S+ + +F C + + S+ Sbjct: 1008 QNILEKTSQ---AFANSWEMMSCPKGNPSSCISIEKEKFAERHCG-------ILLDSSGP 1057 Query: 2316 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIEWRRSDYCPFL 2371 ++CH V P+ + E + T + C L YV C + I R+ C Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHS 1117 Query: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2431 C S ++ V AC D E V +GC C + +++ + C+ ++ Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV--DGCTCPDA--MYQNNEGNCVLKS 1173 Query: 2432 KCAC 2435 +C C Sbjct: 1174 QCDC 1177 >gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo sapiens] Length = 2134 Score = 476 bits (1226), Expect = e-133 Identities = 288/932 (30%), Positives = 447/932 (47%), Gaps = 65/932 (6%) Query: 347 EQCEALLRPPFDACHAYVS-PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGR-P 404 + C ++ F+ C + + C + CQ+ +T C +E +R CA G Sbjct: 687 QHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTST-CDTYSELSRLCASDGPGT 745 Query: 405 LQGWRTQLRQC--TVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIF 462 + WR+ T C E+ Y EC PA+C A DSE CV GC CP G + Sbjct: 746 FESWRSDSDVVCGTQRCPEQHI-YKECGPSNPATCSNVAPFQDSE--CVSGCTCPEGYLL 802 Query: 463 ED----GGCVAPAECPCEFHGTLYPPGSVVKEDCNT-CTCTSGKWECSTAVCPAECSVTG 517 +D G CV AECPCE GT+Y PG V + C + CTC KW C+ A+CP C V G Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEG 862 Query: 518 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 577 TTFDG +Y FP C ++ + ++++++ PC Q G C+ SV+++L+ Sbjct: 863 S-SLTTFDGVKYNFPGNCHFLAVHNED---WSISVELRPCPSGQTGTCLNSVTLLLNSSV 918 Query: 578 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRV-LYDREGLRLY 636 + + + D+ + Y D +I SS +L+V T V++ + ++LY Sbjct: 919 PVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLY 978 Query: 637 LQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLD 696 + + DTVGLCG++N +DDF+S + E T Q F NSW+ +S G+P Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSC----PKGNP-S 1033 Query: 697 PCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDACRC--GQPCLCATL 752 C + ++ ++ + C +L A C ++P PY E+C++ C C Q CLC L Sbjct: 1034 SC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 1092 Query: 753 AHYAHLC-RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE-ACGVDGG 810 +Y C + V +R L C SC + + V C +C+ L+ + +C V+ Sbjct: 1093 GNYVKACAEKETYIVGWRTGL--CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVE-- 1148 Query: 811 DDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDG 870 D V+GC CP Y + + + CV ++QC C+ PG C C+DG Sbjct: 1149 -----DVPVDGCTCPDAMYQNNEGN-CVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202 Query: 871 VMSCDSRAPAAA--CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG-PCLSGCA 927 ++ C C G +V+CSD + RTC + N+ V PC GC Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSD--PKAQRRTNRTCSTR--NIPVFDENLPCKRGCF 1258 Query: 928 CPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 986 CP+G++R+ C P +CPC++ G+EY G C+ C C +GS+ CT + C + C Sbjct: 1259 CPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICH 1318 Query: 987 AYGDRHYRTFDGLPFDFVGACKVHLVKST---SDVSFSVIVENVNCYSSGMICRKFISIN 1043 YG+ H RTFDG + F G C+ ++ + +F ++ E+V C G+ C + I + Sbjct: 1319 IYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCSRKIIVA 1378 Query: 1044 VGNSLIVFDDDSGNPSPESFLDDKQ--------EVHTWRVGFFTLVHFPQEHITLLWDQR 1095 + IV D G + + K+ +HT VG + ++ F Q I ++WD+ Sbjct: 1379 FQDQNIVLQD--GKVTAVKSTESKKCELNANAYSIHT--VGLYLILKF-QNGIIVIWDKN 1433 Query: 1096 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDP 1154 T + V P W G++ GLCGN + ++ T + + EFG+SW + EC DT+ Sbjct: 1434 TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ 1493 Query: 1155 RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCA 1214 C NP + +A ++C IL F CH VD + ++ C+ + C C G FC Sbjct: 1494 TFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1553 Query: 1215 SVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246 +V+ YA C GV V WR P LCP CD++N Sbjct: 1554 AVAMYAEACSAVGVCVSWRKPNLCPVYCDYYN 1585 Score = 211 bits (537), Expect = 8e-54 Identities = 140/455 (30%), Positives = 201/455 (44%), Gaps = 41/455 (9%) Query: 445 DSEIACVDGCYCPNGLIFEDGG-CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 503 D + C GC+CP G++ G CV P +CPC F G Y GSV CN CTC G W Sbjct: 1248 DENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWS 1307 Query: 504 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLN 560 C+ C C + G+ H TFDG+ Y+F CQY + +GTF + ++ PC Sbjct: 1308 CTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCC-- 1365 Query: 561 QDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSVFLRVR 619 +DG ++ QD Q + Q G V + +A+ I + ++L ++ Sbjct: 1366 EDGLTCSRKIIVAFQD---QNIVLQDGKVTAVKSTESKKCELNANAYSIHTVG-LYLILK 1421 Query: 620 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 679 G+ V++D+ RL + +D W GLCG NG+ +DDF + S FGNS Sbjct: 1422 FQNGIIVIWDKN-TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNS 1480 Query: 680 WKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 739 WKT CS V+ + PCD + +++V+ C +L F C + P Y + C + Sbjct: 1481 WKTSQECSDTVAQT--FPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEE 1538 Query: 740 ACRCGQPC----LCATLAHYAHLCRRHGLPVDFRARLPACALSC-------EASKEYSPC 788 AC C C +A YA C G+ V +R + C + C E Y PC Sbjct: 1539 ACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWR-KPNLCPVYCDYYNAPGECRWHYEPC 1597 Query: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPPDT-YLDTQADLCVPRNQCSC 845 +TC+D G S +EGC CP YLD CV ++CSC Sbjct: 1598 GTVTAKTCKDQLV--------GQKFS--SLLEGCYAKCPDSAPYLDENTMKCVSLSECSC 1647 Query: 846 HFQGVDYPPGDSDIPSLGH-CHCKDGVMSCDSRAP 879 + V P G + G C+C G + C AP Sbjct: 1648 FYNDV-IPAGGVIEDNCGRTCYCIAGQLECSETAP 1681 Score = 132 bits (333), Expect = 4e-30 Identities = 107/380 (28%), Positives = 167/380 (43%), Gaps = 34/380 (8%) Query: 146 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYT 204 E +IC +G+ HV TFDG Y G Y+ + + E +F I + P C T Sbjct: 1312 ECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDG-LT 1370 Query: 205 CSRAVSLFFVGEQEIHLAKEVTH----GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTL 260 CSR + + F + + +VT + +L + + + Y+I++ Q+ + Sbjct: 1371 CSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELN--ANAYSIHTVGLYLILKFQNGIIV 1428 Query: 261 AWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQ 320 WD + + + + P G GLCGNNN D KDD T + +EF +SW+ +Q Sbjct: 1429 IWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQ 1485 Query: 321 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LC 378 T + PC NP +CE L F CH V P + C + C Sbjct: 1486 ECSDTVAQ--TFPC-DSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACAC 1542 Query: 379 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIAC 432 G +C A+A YA AC+ G WR + C V+C E + Y C Sbjct: 1543 DMEGKYLGFCTAVAMYAEACSAVG-VCVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTV 1600 Query: 433 CPASCHPRASCVDSEI-ACVDGCY--CPNGLIFEDGG---CVAPAECPCEFHGTLYPPGS 486 +C + V + + ++GCY CP+ + D CV+ +EC C F+ + P G Sbjct: 1601 TAKTC--KDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSC-FYNDVIPAGG 1657 Query: 487 VVKEDC-NTCTCTSGKWECS 505 V++++C TC C +G+ ECS Sbjct: 1658 VIEDNCGRTCYCIAGQLECS 1677 Score = 111 bits (277), Expect = 1e-23 Identities = 114/451 (25%), Positives = 164/451 (36%), Gaps = 83/451 (18%) Query: 105 CAPSYLFSCFNG-GECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRA--------W- 154 C YL G+CV A C C VY G R+ C + W Sbjct: 796 CPEGYLLDDIGEKGKCVLKAECPCESSGT-------VYQPGEVREGPCGSQCTCQDAKWS 848 Query: 155 -------GQHHVE-----TFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 202 G+ VE TFDG+ Y G + V + +SI V P Sbjct: 849 CTEALCPGRCKVEGSSLTTFDGVKYNFPGNCHFLAV-----HNEDWSISVELRPCPSGQT 903 Query: 203 YTCSRAVSLFF-----VGEQEIHLAKEVTHGGMRVQ-------LPHVMGSARLQQLAGYV 250 TC +V+L V + + VT+ +R Q + S+ Q+ Y Sbjct: 904 GTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYF 963 Query: 251 IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFV 310 V+ Q +Y+ M P T GLCG+ N +DD ++S L F Sbjct: 964 HVKLQIQIVPVMQ----LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFA 1019 Query: 311 HSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALL--RPPFDACHA 362 +SW+ + C + NP + + ++ C LL P +CH Sbjct: 1020 NSWEMMS----------------CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHP 1063 Query: 363 YVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE- 421 V+P P+ C C C L Y +ACA+ + GWRT L C C Sbjct: 1064 IVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSG 1121 Query: 422 KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLI-FEDGGCVAPAECPCEF 477 F YN + C +SC R D E VDGC CP+ + +G CV ++C C Sbjct: 1122 LVFKYN--VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 1179 Query: 478 HGTLYPPGSVVKEDCNTCTCTSGKWECSTAV 508 + + PG ++ D N C C G C + Sbjct: 1180 NDEVMQPGKLIHIDDNKCVCRDGILLCQIPI 1210 Score = 75.5 bits (184), Expect = 7e-13 Identities = 56/207 (27%), Positives = 89/207 (42%), Gaps = 26/207 (12%) Query: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS---CATT 2302 GLCG +GD +D T + SV GA + F +SW+ + F DS C Sbjct: 1450 GLCGNNNGDLKDDFTTRYSSVASGALE---FGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1506 Query: 2303 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-------KYVQQPCVALTVYVAMCHK 2355 C ++ + TF CH V P ++ ++ I + KY+ C A+ +Y C Sbjct: 1507 AVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF-CTAVAMYAEACSA 1564 Query: 2356 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEP-----PKTCQDGILGPLDPEHCQVLGEG 2410 VC+ WR+ + CP C + C EP KTC+D ++G + L EG Sbjct: 1565 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG----QKFSSLLEG 1620 Query: 2411 CV--CSEGTILHRRHSALCIPEAKCAC 2435 C C + ++ C+ ++C+C Sbjct: 1621 CYAKCPDSAPYLDENTMKCVSLSECSC 1647 Score = 67.4 bits (163), Expect = 2e-10 Identities = 126/545 (23%), Positives = 194/545 (35%), Gaps = 82/545 (15%) Query: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCP-TPQVLDEVTQRCVYLEDC--- 1463 C W Y+ C + +TC+D + + C CP + LDE T +CV L +C Sbjct: 1590 CRWHYEPCGTVTAKTCKD-QLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1648 Query: 1464 ---VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTAL 1520 V PA V + G T G S+ P S + T T L+ A +T Sbjct: 1649 YNDVIPAGGVIEDNCG-RTCYCIAGQLECSETAPTNSTFAVSTTTATTILSTGAAITLVT 1707 Query: 1521 NPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSS 1580 P TA P ++ ++TT GP P + G+T + + I T ++ Sbjct: 1708 GGPSTAASIPAITTSSSETT----------GTTLGPLTEPFTTGITETSVPIISTSGNAG 1757 Query: 1581 LPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1640 + + G A T V G+ + S R+ PR T AV G GS Sbjct: 1758 MTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA-GTPRVSGETPAV---GGGS-- 1811 Query: 1641 VRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS 1700 TP + A+ S S G+I+ SP +S A + S++G P+ Sbjct: 1812 ---TPGEAGPGATVSGSTGVSAGSITASPGAS---------ATSSESSKSGTTGPSVGGK 1859 Query: 1701 ASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1760 + S+ T + + S +T + ++ + G SP P P +P Sbjct: 1860 TGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTG-----SSPPGKLTRPSPGSP 1914 Query: 1761 PRPAQHTT------------------MATRSPALPPETPAAASLSTATDG---------- 1792 + TT + + ++ T A + + T G Sbjct: 1915 GHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTA 1974 Query: 1793 LAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVA----TPGPKASVITTPLQPQA 1848 ++ TP +S +T P S P + + G S T A + TP A Sbjct: 1975 VSGTPVVSPGAT-PGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAA 2033 Query: 1849 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASM 1908 +T T SPV T AA A + P GT G G + TSG + GT++ Sbjct: 2034 ST----TSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKI-TSGW--SSSGTSTG 2086 Query: 1909 VSVVP 1913 S P Sbjct: 2087 ASNTP 2091 Score = 49.7 bits (117), Expect = 4e-05 Identities = 91/424 (21%), Positives = 152/424 (35%), Gaps = 59/424 (13%) Query: 2047 TSTTCVPIAEQDCVRHI-CLEGQLIR-VNQSQHCPQGAAPPRCGILGLAVRVG------- 2097 T + P + +CV C EG L+ + + C A P C G + G Sbjct: 778 TCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP-CESSGTVYQPGEVREGPC 836 Query: 2098 GDRC--------CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHV 2149 G +C C C RC + S TFDG ++ + D ++V + Sbjct: 837 GSQCTCQDAKWSCTEALCPGRCKV-EGSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVEL 895 Query: 2150 LDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR--FNRKVTVDLQPVWPPVSRYGFRIE 2207 C S G CL + + L V +D+ FN TV + Y +I+ Sbjct: 896 RPCPSGQTGT------CLNSVTLL-LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQ 948 Query: 2208 --DTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLK 2262 + Y+ + +QIQ + L V GLCG + A +D Sbjct: 949 IFNASSSYLQVETYFHVKLQIQIVPVMQLY-VSMPPNQFTDTVGLCGSYNNKAEDDFMSS 1007 Query: 2263 DGSVVGGAEDPAPFLDSWQV-------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT 2315 + ++ F +SW++ PSS S+ + +F C + + S+ Sbjct: 1008 QNILEKTSQ---AFANSWEMMSCPKGNPSSCISIEKEKFAERHCG-------ILLDSSGP 1057 Query: 2316 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIEWRRSDYCPFL 2371 ++CH V P+ + E + T + C L YV C + I R+ C Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHS 1117 Query: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2431 C S ++ V AC D E V +GC C + +++ + C+ ++ Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV--DGCTCPDA--MYQNNEGNCVLKS 1173 Query: 2432 KCAC 2435 +C C Sbjct: 1174 QCDC 1177 >gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] Length = 2639 Score = 430 bits (1105), Expect = e-119 Identities = 243/698 (34%), Positives = 377/698 (54%), Gaps = 39/698 (5%) Query: 570 SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYD 629 +V+L D ++ V + ++ +L ++ ++ P+ +F + R SS + V +GVR+ Sbjct: 347 TVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQ 406 Query: 630 REG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP 688 ++L++ +DQ GLCG FNG DDF + G+ E+T F N+WK S+C Sbjct: 407 LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 466 Query: 689 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC--G 744 + DPC +++++A+Y+ CS+L T F C + + P Y+++C+ D C C Sbjct: 467 KLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 525 Query: 745 QPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRTCQDLAS 801 + CLCA L+ YA C G+ + + R C SC S+ + + C +TC+ L+ Sbjct: 526 EDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 584 Query: 802 PEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 861 ++ ++G V+GC CP T+LD + CVP +CSC+ +G+ GD + Sbjct: 585 ADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAGDVVVRQ 637 Query: 862 LGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 920 C C+DG + C R +C A ++ ++CS+L T L S+ R Q L Sbjct: 638 EERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAAGYY-HT 695 Query: 921 PCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 979 C+SGC CP GL+ G C + +ECPC Y G ++ C+TC C+RG + CT Sbjct: 696 ECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQA 755 Query: 980 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVNCYSSGM 1034 C TC+ YG HY TFDG +DF G C V+ ++S SFS+I ENV C ++G+ Sbjct: 756 VCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGV 815 Query: 1035 ICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHFPQEHIT 1089 C K I I +G + + +D + + E H T VG + +V I Sbjct: 816 TCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE-SSTGII 868 Query: 1090 LLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA-AVEC 1148 ++WD+RTTV ++ P ++G + GLCGNFD ++ N+ T +++ +++ +FG+SW A C Sbjct: 869 VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928 Query: 1149 PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGD 1208 PD + C LNP R +A+K+CSIL S VF ICH VD FY C+ D+C C GGD Sbjct: 929 PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGD 988 Query: 1209 CECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246 CECFC++V++YA +C + G V WRTP LCP CD++N Sbjct: 989 CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026 Score = 239 bits (610), Expect = 3e-62 Identities = 318/1356 (23%), Positives = 477/1356 (35%), Gaps = 232/1356 (17%) Query: 1452 EVTQRCVYLEDCVEPAVWVPTEALGNETLPP----SQGLPTPSDEEPQLSQESP--RTPT 1505 E+ +C +CV + T N T P + PTP+ Q + +P T T Sbjct: 1288 EINVQCC---ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTT 1344 Query: 1506 HRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TESPA 1561 P TP T P T T P +P TQT P+ T + P T++P Sbjct: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1404 Query: 1562 SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPA 1621 S +T + P TP P QTPT TT +T +P T + P Sbjct: 1405 STPITTTTTVTP-TPT----PTGTQTPT---------TTPITTTTTVTPTPTPTGTQAPT 1450 Query: 1622 PRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTP 1681 P T VT P P+ T +P++ P+ + ++ +PT +G+ TP Sbjct: 1451 PTAITTTSTVT-----------PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ----TP 1495 Query: 1682 AVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAE-------QVPV-SPLATRSLEIVL 1732 T + + T V P PT + + STP+T T Q P +P++T + Sbjct: 1496 TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555 Query: 1733 STEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATD 1791 T G + + P+ + + P P P+ P + T + P TP T+T Sbjct: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-VLITTTTTMTPTPTP------TSTK 1608 Query: 1792 GLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP-----GPKASVITTPLQP 1846 TP + + + +G T +P++ T P TP GP T P+ Sbjct: 1609 STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE 1668 Query: 1847 QATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1906 T+ P PP P + + L +T S + P E T+ Sbjct: 1669 LTTSNP-------------------PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709 Query: 1907 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQA 1965 + P TT +S P S S G PT T +S TP + A Sbjct: 1710 TAPPSTPTAPTTTSGG---HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 1766 Query: 1966 GTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDE 2016 T P P S + P S +++ L + + GT Sbjct: 1767 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLS 1826 Query: 2017 ATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------------------- 2057 T E S P+ T +ST P Sbjct: 1827 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886 Query: 2058 --DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIF 2114 DC C + + + + P P C VRV D CC WEC C C+ + Sbjct: 1887 LCDCFMATCKYNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGW 1944 Query: 2115 PDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLV 2168 D +VTFDG + + Y+L + SP +D + + + P C Sbjct: 1945 GDPHYVTFDGLYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPR 1997 Query: 2169 MLNMTHLAHQVTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQI 2223 L + H +V I + +V V+ Q V P +YG + +G Y++ P + Sbjct: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057 Query: 2224 QWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP 2283 + + G CG C ++D L G +V E A D W V Sbjct: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVN 2114 Query: 2284 ---------SSLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFC 2329 SS T+ P TT DC SP +++ + F+ CH VPP+ + Sbjct: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYY 2174 Query: 2330 ELWIRDTKYV---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTA 2384 + + D+ ++ C +L Y A+C + ++C++WR + C C S YQAC A Sbjct: 2175 DACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPA 2234 Query: 2385 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2444 EP TC+ ++ VL EGC C EGT+ + +C+ C C VPR Sbjct: 2235 EEP--TCKSSS----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPRE 2286 Query: 2445 LGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTV 2503 GE + C + I+ C C+ G +A + D CC TV Sbjct: 2287 FGEHFEFDCKNCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 2344 Query: 2504 CVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQIL 2560 C CN +LC+ C G + + CCP Y CE +C AE P Sbjct: 2345 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG------- 2396 Query: 2561 ITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQ 2620 Y C DC C + V NT L C + C Sbjct: 2397 ---------SPVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTS 2432 Query: 2621 CGLGTALVEVWSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQL 2662 C G L+E +P CC K CE C D + P C + ++ Sbjct: 2433 CSPGFELME--APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKI 2488 Query: 2663 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPG 2698 + + SV N+ C ++ A +C+ + M G Sbjct: 2489 HNQLISSVSNIT-CPNFD---ASICIPGSITFMPNG 2520 Score = 231 bits (589), Expect = 8e-60 Identities = 190/769 (24%), Positives = 312/769 (40%), Gaps = 164/769 (21%) Query: 230 MRVQLPHVMGSARLQQLAGYVIVRHQSA---FTLAWDGASAVYIKMSPELLGWTHGLCGN 286 ++V LPHV S + + + Y I+ + + +++ + G GLCGN Sbjct: 372 LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 431 Query: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346 N DD T+SG + F ++W+ Q+ PC N + Sbjct: 432 FNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDD----PC-SLNIESANYAE 486 Query: 347 EQCEALLRP--PFDACHAYVSPLPF-------TASCTSD---LCQSMGD---------VA 385 C L + PF CH+ V P + T +C ++ LC ++ V Sbjct: 487 HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546 Query: 386 TW------------------------------CRALAEYARACAQAGRPLQGW------- 408 W CR+L+E C + P+ G Sbjct: 547 LWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTF 606 Query: 409 ---------------------------------RTQLRQCTVHCKEKAFTYNECIA---- 431 R R +HC++ C A Sbjct: 607 LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIH 666 Query: 432 ------CCPASCHPRASCVDSEIA------CVDGCYCPNGLIFED-GGCVAPAECPCEFH 478 A+ PRA + A CV GC CP+GL+ + GGCV ECPC + Sbjct: 667 MDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN 726 Query: 479 GTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYI 538 LY G+ +K DCNTCTC G+W C+ AVC CS+ G H+ TFDG+ Y F C Y+ Sbjct: 727 NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYV 786 Query: 539 -----LAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFD 593 ++ S G+F++ +N PCG C +++ + + + ++ L D Sbjct: 787 AVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRT-----------ELKLED 834 Query: 594 QYKIIPPYTDD---AFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGL 650 +++++ + A+ R + +L V ++ G+ V++D+ +++++ + GL Sbjct: 835 KHRVVIQRDEGHHVAYTTREVGQ-YLVVESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGL 892 Query: 651 CGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQ 710 CG F+ + +DF + + S+ FGNSWK C P VS +P +PC ++ S++ + Sbjct: 893 CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEK 950 Query: 711 ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPV 766 CS+L +F+ C + + P P++E C D+C C C C+ +A YA C + G V Sbjct: 951 QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV 1010 Query: 767 DFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 819 +R C + C E Y PC TC+ + G+ +S + Sbjct: 1011 FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN-----GIHSNISVS---YL 1061 Query: 820 EGC--ACPPDTYL-DTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 865 EGC CP D + + CV ++C C+ + YPPG S +P+ C Sbjct: 1062 EGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGAS-VPTEETC 1109 Score = 157 bits (398), Expect = 1e-37 Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%) Query: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 206 C +G H TFDG YY G SY V G++ G SFSI N P CG++ TCS Sbjct: 761 CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 818 Query: 207 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 266 +A+ +F +G E+ L + R + HV + R ++ Y++V + + WD + Sbjct: 819 KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 875 Query: 267 AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 326 V+IK++P G GLCGN + +D T + ++F +SW+E P P Sbjct: 876 TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE----APTCPDV 931 Query: 327 SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDV 384 S+ P P L NP +QC L F CH+ V P PF +C D C + GD Sbjct: 932 STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 989 Query: 385 ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC------KEKAFTYNECIACCPASCH 438 +C A+A YA+ C + G + WRT C + C E + Y C +C Sbjct: 990 ECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1047 Query: 439 P-RASCVDSEIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 490 + ++ ++GCY CP I+E+ CV +C C T YPPG+ V +E Sbjct: 1048 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1107 Query: 491 DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 526 C +C CT+ S VC E G I T DG Sbjct: 1108 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1136 Score = 119 bits (297), Expect = 6e-26 Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%) Query: 475 CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 517 C+++ T+ +VK +C TC++G WEC C+ G Sbjct: 1895 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 1945 Query: 518 DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 575 D H+ TFDG Y++ C Y+L + S S F V + N C N +C +++ ++ H+ Sbjct: 1946 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 2004 Query: 576 DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632 + V + + ++ + PY E+ + ++ +GV V Y+ G Sbjct: 2005 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 2062 Query: 633 LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 690 L +++ R+ +T G CGT T DD + P G S + + W P Sbjct: 2063 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 2122 Query: 691 -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741 S S V + + C ++ +FA C A + P Y++ C D+C Sbjct: 2123 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 2182 Query: 742 -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 799 G CA+L YA LC + + +D+R AC + C + +EY C TC+ Sbjct: 2183 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 2242 Query: 800 ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 855 +S + + VEGC CP T D+CV C C G D P G Sbjct: 2243 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 2288 Query: 856 DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 905 + +C C +G + C S+ P C + VN +D ++ + + Sbjct: 2289 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 2348 Query: 906 T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 955 T C+++ + L + + G CP +G+ HG+A EY Sbjct: 2349 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 2394 Query: 956 PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 986 PG V S C CVC CT PC ++C+ Sbjct: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434 Score = 115 bits (289), Expect = 5e-25 Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%) Query: 146 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 205 E D C WG H TFDGLYY G +Y LV P +F + + N + +C Sbjct: 1936 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 1995 Query: 206 SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 255 R +L E + L K V M+VQ LP+ G Q YV+ + Sbjct: 1996 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 2053 Query: 256 SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 315 ++++G S T G CG DD + SG++ + W Sbjct: 2054 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 2113 Query: 316 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 369 P++P P +SS + P + G ++ C+ + F CHA V P + Sbjct: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 2173 Query: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 428 +C D C G + C +L YA CAQ L WR C V C ++ E Sbjct: 2174 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 2227 Query: 429 CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 476 AC PA +C +S ++ + V+GC+CP G + + GCV P P E Sbjct: 2228 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286 Query: 477 FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 514 F G + DC C C G S +C P CS Sbjct: 2287 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 2315 Score = 109 bits (273), Expect = 3e-23 Identities = 91/329 (27%), Positives = 145/329 (44%), Gaps = 32/329 (9%) Query: 513 CSVTGDIHFTTFDGRRYTFPATCQYILAKS--RSSGTFTVTLQNAPCGLNQDGACVQSVS 570 CS G+ H+ TFDG + FP C Y A S F V L+ P G + A V+S+ Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGP-GQAEAPAGVESIL 95 Query: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630 + + D T+ + + + + P+ I + S + +V + G+ ++++R Sbjct: 96 LTIKDD-----TIYLTRHLAVLNGAVVSTPHYSPGLLIEK-SDAYTKVYSRAGLTLMWNR 149 Query: 631 EGLRLYLQVDQRWVEDTVGLCGTFNG-NTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 689 E L L++D ++ T GLCG +NG + +FLS GV S P FGN K + Sbjct: 150 ED-ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLFS-PLEFGNMQKINQ--PDV 204 Query: 690 VSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC--GQPC 747 V P + + + + +LT E FA C + PY C++D CRC G C Sbjct: 205 VCEDPEEEV-APASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263 Query: 748 LCATLAHYAHLC-RRHGLPVDFR----ARLPACALSCEASKEYSPCVAPCGRTCQDLASP 802 +C+T+A ++ C G P ++R A P + +C + Y +PC TC L Sbjct: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323 Query: 803 EACGVDGGDDLSRDECVEGCACPPDTYLD 831 C + ++GC CP D Sbjct: 324 SLC---------EEHRMDGCFCPEGAQAD 343 Score = 96.7 bits (239), Expect = 3e-19 Identities = 152/720 (21%), Positives = 241/720 (33%), Gaps = 105/720 (14%) Query: 1408 CEWRYDACASPCFQTCRDPRAA-SCRDVPRGRSCVPVCPTPQ-VLDEVTQRCVYLEDC-- 1463 CEW Y+ C + F+TCR S V C P CP + + +E ++CV + C Sbjct: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090 Query: 1464 ------VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQ-LSQESPRTPTHRPALTPAAPL 1516 P VPTE + + EE + L+Q + P + Sbjct: 1091 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150 Query: 1517 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1576 N T ++ T T P T + PT S + TP Sbjct: 1151 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSS----------TVLSTTP 1200 Query: 1577 ESSSL---PVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFP-------- 1625 + L + P+ G G ET G+P + RS P Sbjct: 1201 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1256 Query: 1626 ---------LMTKAVTVRGHGSLPV-----------------RTTPPQPSLTASPSSRPV 1659 L+ K + G +P+ + T + T +P+ P+ Sbjct: 1257 QLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPI 1316 Query: 1660 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGT------ 1713 + ++ +PT + + TP T + T P PT + + +TP+T T Sbjct: 1317 TTTTTVTPTPTPTSTQSTTPTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1373 Query: 1714 -AAEQVP-VSPLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA 1770 Q P +P+ T + T G + S P+ + + P P P+ P T + Sbjct: 1374 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT-TPIT 1432 Query: 1771 TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAP- 1829 T + P TP T T T + + P+ +G T+ P+ T P Sbjct: 1433 TTTTVTPTPTP------TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486 Query: 1830 -----VATPGPKASVITTPLQP--------QATTLPAQTLSPVLPFTPAAMTQAHPPTHI 1876 TP P A TT + P T+ P T + V P TQ PT I Sbjct: 1487 PTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPI 1546 Query: 1877 APPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSL-PTSMY 1935 + T G PT+ P+ T + P + T +++ ++ PT Sbjct: 1547 STTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604 Query: 1936 GSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVL 1993 S + T +TP T+ P G Q T +P+ T+ ++ T Sbjct: 1605 TSTKS--TTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS 1662 Query: 1994 LPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053 +AE ++ P + +T+ P S LS L A+ T+ A ST P Sbjct: 1663 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 1719 Score = 91.3 bits (225), Expect = 1e-17 Identities = 78/317 (24%), Positives = 124/317 (39%), Gaps = 18/317 (5%) Query: 149 SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 208 ++C WG H +TFDG + G Y + F++ + P +P Sbjct: 35 NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94 Query: 209 VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 267 L + + I+L + + G V PH +++ Y V ++ TL W+ A Sbjct: 95 --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152 Query: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327 + +++ + T GLCG+ N S G L + EF + Q NQP Sbjct: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203 Query: 328 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 386 + P + P + +CE LL F C V P+ +C D C+ G Sbjct: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263 Query: 387 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKA---FTYNECIACCPASC-HPRAS 442 C +AE++R C+ AG WRT + + Y E + C +C H S Sbjct: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323 Query: 443 CVDSEIACVDGCYCPNG 459 + E +DGC+CP G Sbjct: 324 SLCEEHR-MDGCFCPEG 339 Score = 75.5 bits (184), Expect = 7e-13 Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%) Query: 976 CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 1033 C C CT +GD HY TFDGL + + G C LV+ S S +F V ++N +C + Sbjct: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991 Query: 1034 MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1083 + C + + + ++ P ++Q V ++ G +V Sbjct: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051 Query: 1084 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1143 P+ + + ++ + ++ G CG T ++ P ++N + W Sbjct: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111 Query: 1144 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1182 + CP + P C +PL C ++ +F Sbjct: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 2163 Query: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1240 CH +V +Y C+ D+C G EC AS+ AYA C Q + +DWR T C Sbjct: 2164 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 2220 Query: 1241 DCDFFNKVLGKGP 1253 +C + GP Sbjct: 2221 ECPSHREYQACGP 2233 Score = 67.4 bits (163), Expect = 2e-10 Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%) Query: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2160 C C CSI+ ++TFDG + Y+ Q C ++++LG Sbjct: 752 CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 800 Query: 2161 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2210 F ++ N+ T + I F + + L+ V + + + G Sbjct: 801 ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 856 Query: 2211 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2270 ++ + + I + W + ++ + + K GLCG D + ND T +D VV Sbjct: 857 QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 915 Query: 2271 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2321 D F +SW+ + V P+ C A CS ++ + FS CH Sbjct: 916 LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 965 Query: 2322 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2375 V P+ F E + D+ C A+ Y C K C+ WR D CP C Sbjct: 966 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1025 Query: 2376 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2426 + C EP +TC+ +GI + + EGC C + ++ Sbjct: 1026 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1081 Query: 2427 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2462 C+ KC C D+ P A T + S C + Q Sbjct: 1082 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1119 Score = 66.6 bits (161), Expect = 3e-10 Identities = 66/274 (24%), Positives = 120/274 (43%), Gaps = 43/274 (15%) Query: 983 STCTAYGDRHYRTFDGLPFDFVGACK---------------VHLVKSTSDVSFSVIVENV 1027 + C+ +G+ HY+TFDG F F G C VHL + VE++ Sbjct: 35 NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94 Query: 1028 NCYSSGMICRKFISINVGNSLIVFDD---DSGNPSPESFLDDKQEVHTWRVGFFTLVHFP 1084 ++ K +I + L V + + + SP L +K + +T + Sbjct: 95 ------LLTIKDDTIYLTRHLAVLNGAVVSTPHYSP-GLLIEKSDAYT--------KVYS 139 Query: 1085 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFD-LKTINEMRTPENLELTNPQEFGSSW 1143 + +TL+W++ + ++ +++ GLCG+++ L++ +E + L +P EFG+ Sbjct: 140 RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNM- 196 Query: 1144 AAVECPDTL--DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTC 1201 + PD + DP + E A+ E +L +E F C +V + + C D C Sbjct: 197 QKINQPDVVCEDPEEEVAPASCSEHRAECE-RLLTAEAFADCQDLVPLEPYLRACQQDRC 255 Query: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRT 1234 C G C C++V+ ++ QC G +WRT Sbjct: 256 RCPGGD--TCVCSTVAEFSRQCSHAGGRPGNWRT 287 Score = 51.6 bits (122), Expect = 1e-05 Identities = 59/226 (26%), Positives = 84/226 (37%), Gaps = 39/226 (17%) Query: 2232 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2291 + V + S+ Q GLCG +G +D G V A F ++W+ SS + Sbjct: 413 LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSCHD--K 467 Query: 2292 TRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYVQQP-- 2342 + D C+ S C + T F CH V P + + DT Q Sbjct: 468 LDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNED 527 Query: 2343 --CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTACEPPK 2389 C AL+ Y C V + WR CP FL + + Q C + E Sbjct: 528 CLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587 Query: 2390 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435 C +G P+D GC C + T L + C+P AKC+C Sbjct: 588 HCLEGF-APVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 621 >gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo sapiens] Length = 3003 Score = 310 bits (793), Expect = 2e-83 Identities = 311/1220 (25%), Positives = 449/1220 (36%), Gaps = 196/1220 (16%) Query: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177 H C ++ G RC + + P+R C+ G H +FDG + G +Y L Sbjct: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890 Query: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235 VG +F + V N+ + GS + +RAV V + + +A + G +V + Sbjct: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945 Query: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286 V+ Q G V +VR T+ +D + V K+ GLCGN Sbjct: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005 Query: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346 N DP DDL G + + F +SWQE+ PG + P L Sbjct: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062 Query: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404 +C L P PF CH+ + P C D C G C ALA YA AC AG Sbjct: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122 Query: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464 + WR++ C + C + Y C CP SC C +GC C G Sbjct: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180 Query: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509 C+ A C C GT +PPG C++ C C G C ++ C Sbjct: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240 Query: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557 + C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N Sbjct: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300 Query: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612 G + VQ + L + R+ D+ L P +IR Sbjct: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352 Query: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670 + + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G Sbjct: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409 Query: 671 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 719 FGNSW+ + SP + +P P C L+ + C +L+ Sbjct: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469 Query: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776 + C + P + C D C G LC+ + Y C+ G V+ C Sbjct: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529 Query: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836 + C + Y C C C L++P C +D C EGC C + QA Sbjct: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578 Query: 837 CVPRNQCSCHFQGVDYPPGDS----DIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNC 892 CVP QC C+ GV Y P + + CH G M C +C GQV Sbjct: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKG-MVCQEH----SCKPGQV---- 1629 Query: 893 SDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGK 952 C+ LS + PC HG C Sbjct: 1630 --------------CQPSGGILSCVTKDPC------------HGVTC------------- 1650 Query: 953 EYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL- 1011 P TC Q G C L +TC +GD HY +FDG FDF G C L Sbjct: 1651 ---------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLA 1700 Query: 1012 ------VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG-------- 1056 V + F+V +N N + + + +++ +G ++ + D+ G Sbjct: 1701 TTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNG 1760 Query: 1057 --NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLC 1114 P S D + V + F + + +D V V + G + GLC Sbjct: 1761 VLTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLC 1817 Query: 1115 GNFDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREP 1166 GN D N+ P + +G SW A EC + C + L + Sbjct: 1818 GNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQY 1874 Query: 1167 FAKKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQC 1223 C L S F CH V F+ C+ D C GGD + C ++++Y C Sbjct: 1875 EGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAAC 1932 Query: 1224 CQHGVAV-DWRTPRLCPYDC 1242 GV + DWR C C Sbjct: 1933 QAAGVVIEDWRAQVGCEITC 1952 Score = 296 bits (758), Expect = 2e-79 Identities = 305/1176 (25%), Positives = 449/1176 (38%), Gaps = 199/1176 (16%) Query: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199 P ++ C WG H +FDG + G +Y L P + F++ N + G Sbjct: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725 Query: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK----EVTHGGMRVQLPHVMGSARLQ--QLAGYVIV 252 + + R V++ +G IH + V G+ LP + R+ Q A ++ Sbjct: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785 Query: 253 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312 +++D V + + G GLCGN + +P +D V +G L + + S Sbjct: 1786 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 1845 Query: 313 WQEQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPL 367 W+ AP P S P P L+Q G G + PF CHA+V P Sbjct: 1846 WR--APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLASGTGGPFTTCHAHVPPE 1901 Query: 368 PFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYN 427 F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y Sbjct: 1902 SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YE 1959 Query: 428 ECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYP 483 C CPASC P + E CV+GC C G + CV C C +GT + Sbjct: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHE 2019 Query: 484 PGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGD 518 GS D C+ C C G C+ A C AEC GD Sbjct: 2020 AGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 2079 Query: 519 IHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVIL 573 H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ + Sbjct: 2080 PHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQI 2138 Query: 574 HQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632 + +TL+ L D + P+ D+ LS + V T G+ + +D + Sbjct: 2139 Y---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDS 2195 Query: 633 LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLV 690 + L+V + GLCG +N + DD + G P W+ A C V Sbjct: 2196 F-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECV 2246 Query: 691 SGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP- 746 S PC Q + AC V+ T APC + P YF+ C DAC+ G P Sbjct: 2247 SKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306 Query: 747 CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACG 806 LC +A Y C+ G + R C L C A Y C C +C L++PE C Sbjct: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC- 2365 Query: 807 VDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH 866 C EGC C D D CVP QC C G YP G+ P Sbjct: 2366 --------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG----- 2410 Query: 867 CKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926 C+ R P G V TC++ Sbjct: 2411 -----PECERRCECG--PGGHV-----------------TCQE----------------- 2429 Query: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 986 G AC EEC + + CH C R C Sbjct: 2430 ---------GAACGPHEECRL----------EDGVQACHATGCGR-------------CL 2457 Query: 987 AYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR----- 1037 A G HY T DG +D G+C L + D FS+++E ++G + R Sbjct: 2458 ANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTV 2514 Query: 1038 --KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQR 1095 + +S+ G + V + P + E +V + + LL+D Sbjct: 2515 AGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGD 2567 Query: 1096 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDT 1151 + + ++G+L GLCGNF+ ++ P ++ + FG++W A C + Sbjct: 2568 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 2627 Query: 1152 LDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGG 1207 P+ +C+ + + C L + F C V+ + ++ C+ D C+Q G Sbjct: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKG 2685 Query: 1208 DCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242 D C S++AY C GVAV WRT CP C Sbjct: 2686 DKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721 Score = 280 bits (716), Expect = 1e-74 Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%) Query: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186 A G RCQ+V E ++CRA G H TFDG Y + G SYT+V + Sbjct: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509 Query: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235 +FS++ N+ + SR VS +VG + + +T G R +LP Sbjct: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560 Query: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293 + RL+ Q +V + +D + + + GLCGN N DP D Sbjct: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620 Query: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351 D +T G L D VEF SW+ + L C P G + E Sbjct: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672 Query: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405 L PF CH + P PF C DLC G+ + CR L+ YA+AC + G + Sbjct: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732 Query: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464 WR+ C + C + Y C CP SC+ A+ + S CV+GC C G + Sbjct: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790 Query: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515 G CV + C C F G PG V D C CTC + + CPA CSV Sbjct: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850 Query: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555 +GD H+ +FDGRR+ F TC Y+L S F V ++N Sbjct: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910 Query: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614 G +Q + ++V V + + V G VL+ D + +P D ++ R Sbjct: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968 Query: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674 + VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G + Sbjct: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026 Query: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730 FGNSW +T C G D + S C +L F C + L P Sbjct: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085 Query: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788 C D C GQ LC LA YA C+ G V C LSC Y C Sbjct: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145 Query: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848 C +C DL P CG EC EGC C D + C+P C C Q Sbjct: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194 Query: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886 G +PPG + P G CHC++ G++SC+S + P AC P+G Sbjct: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239 Score = 254 bits (649), Expect = 9e-67 Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%) Query: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174 GG V PA C P Q + P + C+AWG H T DG + G Sbjct: 2040 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 2097 Query: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228 Y L H P ++F++ V N+ + GS + +R+V+L +++ Sbjct: 2098 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2156 Query: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287 G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN Sbjct: 2157 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 2216 Query: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345 N DP DDL GK V E P P T P Q++ G GV Sbjct: 2217 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2270 Query: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405 + L P CH V P + C D CQ G C A+A Y AC AG L Sbjct: 2271 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2326 Query: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465 WR C + C + Y C CP SC ++ E AC +GC C G + Sbjct: 2327 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 2384 Query: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500 CV +C C G YP PG + C C G Sbjct: 2385 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 2444 Query: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556 C C C G IH+ T DGR Y +C Y+LA+ F++ L+ Sbjct: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503 Query: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616 G + +L + V+L Q V + + +P ++ L Sbjct: 2504 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 2554 Query: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676 + T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F Sbjct: 2555 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 2611 Query: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731 G +W+ + G C V L + A Y S +AC L FA C A LSP Sbjct: 2612 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 2671 Query: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789 YF QC D C + + LC +LA Y C+ G+ V C L C A YS C Sbjct: 2672 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 2731 Query: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849 C +C L+ C C EGC C D +L +Q +C+P C C G Sbjct: 2732 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 2780 Query: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888 P S + S C C S AA CP G+V Sbjct: 2781 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 2818 Score = 161 bits (408), Expect = 8e-39 Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%) Query: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161 R +C P +C G C +CR + Q + G R C A G H T Sbjct: 2416 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 2466 Query: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219 DG Y L G SY L V +P + FSI + + L V Q + Sbjct: 2467 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 2519 Query: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277 LA+ +VT G V LP +G R+ ++++ L +DG + + + + Sbjct: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 2579 Query: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337 G GLCGN N + DD V +G V F +W+ ++ G P CL + Sbjct: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 2639 Query: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395 + E C L P PF C A +SP + C DLC GD A CR+LA Y Sbjct: 2640 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 2698 Query: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455 AC AG ++ WRT C +HC + Y+ C C SC + C +GC Sbjct: 2699 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 2756 Query: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510 C + + G C+ +C C +G P S++ DC+ C+C+S C A CP Sbjct: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816 Query: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554 AE C ++ + TTFDG R + Y L+ T+ Sbjct: 2817 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 2876 Query: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614 + ++V + VTLT V + +P + + R Sbjct: 2877 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 2936 Query: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662 L VR GV+V G ++ + V G CG F+G+ +D+ Sbjct: 2937 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983 Score = 115 bits (287), Expect = 8e-25 Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%) Query: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926 G+ D R+PA +CPA + C + +C + S R PC+ GC Sbjct: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780 Query: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983 C G + G AC C CT++G + PG +V + C C C + Q T S Sbjct: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840 Query: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017 TC GD HY +FDG FDF+G C LV S Sbjct: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900 Query: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068 +F V+VEN + S + + + + + V DD P D Sbjct: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958 Query: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128 +V +R G +V +T+ +D V + + L GLCGNF+ +++ Sbjct: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017 Query: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182 + N FG+SW P +P D L+ L ++ +K EC IL F Sbjct: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077 Query: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241 CH +D +C+ D C G C +++ YA C G V WR+ LCP Sbjct: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135 Query: 1242 C 1242 C Sbjct: 1136 C 1136 Score = 98.6 bits (244), Expect = 8e-20 Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%) Query: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022 C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV Sbjct: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513 Query: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073 +N + Y + R + +S+ G V D+ + P S + + V+ Sbjct: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573 Query: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133 + F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+ Sbjct: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630 Query: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186 + EF SSW + C D C + + C +L L F +CH Sbjct: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690 Query: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242 +D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C Sbjct: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745 Score = 92.4 bits (228), Expect = 6e-18 Identities = 116/501 (23%), Positives = 186/501 (37%), Gaps = 85/501 (16%) Query: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078 S P+LS EG A + + TCVP+ + C+ +G+ + + + Sbjct: 2355 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 2410 Query: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125 P+ CG G G C P EC AC RC + ++T DG Sbjct: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 2470 Query: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180 L Y+L+Q DE ++ + + +L L + +A QV Sbjct: 2471 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 2519 Query: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240 ++VTVD + V PV+ R+ G ++ T +++ + + L++ S S Sbjct: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 2576 Query: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298 +G GLCG +G+ ++D L +GS E F +W+ P S G+ Sbjct: 2577 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 2627 Query: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342 C C CL + AC + P+ + C+ + ++Y +Q Sbjct: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687 Query: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398 C +L Y A C V ++ WR +CP C + S Y C C+ G+ G Sbjct: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 2746 Query: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457 C EGC C + +L + +CIP C CT + S S C Sbjct: 2747 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERC 2798 Query: 2458 QHQCQAPDTIVPVDLGCPSPR 2478 C + + GCP R Sbjct: 2799 --SCSSSSGLTCQAAGCPPGR 2817 Score = 91.3 bits (225), Expect = 1e-17 Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%) Query: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093 GLA+A+ T A+ T + E C C GQ RC + Sbjct: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457 Query: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151 VGG C + E C D + TFDG + Y + + S D+ L ++ Sbjct: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514 Query: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208 K+ + G LV + +H V++ R V VD Q PVS R+ Sbjct: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572 Query: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268 +G ++ + + + L + ++ Q GLCG +GD A+D DG++ Sbjct: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629 Query: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315 A D F SW++ D C +C C R+ T Sbjct: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681 Query: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368 F+ CH + P F E + D V C L+ Y C + + + +WR C Sbjct: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741 Query: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426 P C ++S Y+ C AC P +C G P +C + EGCVC G + Sbjct: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792 Query: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461 C+P + C CT G+ A G E W L CQ +C Sbjct: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824 Score = 90.1 bits (222), Expect = 3e-17 Identities = 122/510 (23%), Positives = 186/510 (36%), Gaps = 84/510 (16%) Query: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123 C EG L+ S P A P G LG C + C+ S D + TFD Sbjct: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264 Query: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2183 G +Y+L+Q+ +H N+ N ++ + + +++ Sbjct: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324 Query: 2184 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2242 KVTV+ + PV +I + H ++ +D ++ + + V Sbjct: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384 Query: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP---D 2297 Q GLCG +GD +D +GS G A + F +SW+ VP S + T P D Sbjct: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDS-PCLPPTPCPPGSED 1440 Query: 2298 SCATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQ 2341 + C P L ++S+ T S+CH+ V P+ + I D + Sbjct: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500 Query: 2342 PCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQD 2393 C + YV+ C +E WR +CP C +S Y+ C C P CQD Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560 Query: 2394 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSL 2453 G EGC C G + + C+P +C C + GV E + L Sbjct: 1561 G------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVL 1601 Query: 2454 SGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLC 2511 C+ Q C A +V + C +P + L TKDP C Sbjct: 1602 IDNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------C 1645 Query: 2512 EGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541 G+ TCRP + C P+Y C Sbjct: 1646 HGV--TCRPQETCKEQGGQGVCLPNYEATC 1673 Score = 84.7 bits (208), Expect = 1e-15 Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%) Query: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140 P CG + GL + G C P+ C + D +VT DG Y+LS Sbjct: 2047 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 2103 Query: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194 C LG N F + + N VT+ +N +T+ + Sbjct: 2104 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2148 Query: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241 WP + F+++ H ++ + T S + + + S + + + Sbjct: 2149 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2203 Query: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294 A LCG+C D A+DL G VGGA+ + S PS T Q F Sbjct: 2204 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2262 Query: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349 PD+C + + + CH VPP + + + D VQ C A+ Y Sbjct: 2263 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315 Query: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407 VA C + EWRR D+CP C + S Y+ C +C P +C PE C+ Sbjct: 2316 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 2369 Query: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462 EGCVC G +L C+P +C C G LGE + C+ +C+ Sbjct: 2370 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 2418 Score = 78.6 bits (192), Expect = 9e-14 Identities = 118/489 (24%), Positives = 165/489 (33%), Gaps = 103/489 (21%) Query: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112 A++ C R G +V Q CP G RC +V+ G C P C+ S Sbjct: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RC-----SVQNGLLGCYPDRFGTCQGS 867 Query: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172 D +V+FDG Y+L S + + P V++ Sbjct: 868 --GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRVLVEN 909 Query: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWLHSSG 2230 H Q + R V V+ + V V R G + D Y+ +D Q+Q Sbjct: 910 EHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGR 967 Query: 2231 LMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVGGAED 2272 +V +K + LCG+C +GD A+DL L+ G G A + Sbjct: 968 DAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---GQAAN 1024 Query: 2273 PAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSACHRF 2322 F +SWQ T G P C D ++ S F CH Sbjct: 1025 ALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSK 1081 Query: 2323 VPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCS 2373 + P+ +RD Y + C AL Y A C + WR + CP C Sbjct: 1082 LDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP 1137 Query: 2374 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433 S Y+AC C P +C D + C EGCVC EG L C+P A C Sbjct: 1138 PHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLPLASC 1189 Query: 2434 ACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGCPSPR 2478 C G G+T+ L C C + P LGC + Sbjct: 1190 GCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG 1248 Query: 2479 PESCLRFGE 2487 +C G+ Sbjct: 1249 SSTCQASGD 1257 Score = 63.9 bits (154), Expect = 2e-09 Identities = 113/434 (26%), Positives = 158/434 (36%), Gaps = 67/434 (15%) Query: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155 C P +E C ++ D + +FDG Y+L+ + + LT + K+ Sbjct: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722 Query: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWP--PVSRYGFRIEDTGH 2211 N G+ P V ++ + L ++I + KV V + V PVS RI Sbjct: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQG 1779 Query: 2212 MYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGG 2269 L +D +Q + V+ + S G GLCG D + ND +G++ Sbjct: 1780 ASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL--- 1835 Query: 2270 AEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSN 2313 AP + W S + G D C + C C L + Sbjct: 1836 ----APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLASGTG 1888 Query: 2314 RTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYC 2368 F+ CH VPPESF + + D C AL YVA C V IE WR C Sbjct: 1889 GPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC 1948 Query: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSAL 2426 C +S Y+ C C P +C PL P C+ EGC C G +L + Sbjct: 1949 EITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADR 2001 Query: 2427 CIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRF 2485 C+P C C + A E W G C C+ G P SC Sbjct: 2002 CVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GL 2052 Query: 2486 GEVALLLPTKDPCC 2499 GEV LLP+ C Sbjct: 2053 GEVCGLLPSGQHGC 2066 Score = 32.7 bits (73), Expect = 5.4 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%) Query: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 940 CPA + C+ RTC+ LS C GC C L C Sbjct: 2721 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 2769 Query: 941 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 973 ++C CT G+ Y P + S C C C S Sbjct: 2770 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 2804 >gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] Length = 5405 Score = 308 bits (790), Expect = 4e-83 Identities = 310/1218 (25%), Positives = 448/1218 (36%), Gaps = 194/1218 (15%) Query: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177 H C ++ G RC + + P+R C+ G H +FDG + G +Y L Sbjct: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890 Query: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235 VG +F + V N+ + GS + +RAV V + + +A + G +V + Sbjct: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945 Query: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286 V+ Q G V +VR T+ +D + V K+ GLCGN Sbjct: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005 Query: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346 N DP DDL G + + F +SWQE+ PG + P L Sbjct: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062 Query: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404 +C L P PF CH+ + P C D C G C ALA YA AC AG Sbjct: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122 Query: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464 + WR++ C + C + Y C CP SC C +GC C G Sbjct: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180 Query: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509 C+ A C C GT +PPG C++ C C G C ++ C Sbjct: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240 Query: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557 + C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N Sbjct: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300 Query: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612 G + VQ + L + R+ D+ L P +IR Sbjct: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352 Query: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670 + + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G Sbjct: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409 Query: 671 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 719 FGNSW+ + SP + +P P C L+ + C +L+ Sbjct: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469 Query: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776 + C + P + C D C G LC+ + Y C+ G V+ C Sbjct: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529 Query: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836 + C + Y C C C L++P C +D C EGC C + QA Sbjct: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578 Query: 837 CVPRNQCSCHFQGVDYPPGDS----DIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNC 892 CVP QC C+ GV Y P + + CH G M C +C GQV Sbjct: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKG-MVCQEH----SCKPGQV---- 1629 Query: 893 SDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGK 952 C+ LS + PC HG C Sbjct: 1630 --------------CQPSGGILSCVTKDPC------------HGVTC------------- 1650 Query: 953 EYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL- 1011 P TC Q G C L +TC +GD HY +FDG FDF G C L Sbjct: 1651 ---------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLA 1700 Query: 1012 ------VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG-------- 1056 V + F+V +N N + + + +++ +G ++ + D+ G Sbjct: 1701 TTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVL 1760 Query: 1057 NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGN 1116 P S D + V + F + + +D V V + G + GLCGN Sbjct: 1761 TALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGN 1817 Query: 1117 FDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFA 1168 D N+ P + +G SW A EC + C + L + Sbjct: 1818 MDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEG 1874 Query: 1169 KKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQ 1225 C L F CH V F+ C+ D C GGD + C ++++Y C Sbjct: 1875 PGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQA 1932 Query: 1226 HGVAV-DWRTPRLCPYDC 1242 GV + DWR C C Sbjct: 1933 AGVVIEDWRAQVGCEITC 1950 Score = 306 bits (785), Expect = 1e-82 Identities = 321/1217 (26%), Positives = 449/1217 (36%), Gaps = 193/1217 (15%) Query: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174 GG V PA C P Q + P + C+AWG H T DG + G Sbjct: 3239 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 3296 Query: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228 Y L H P ++F++ V N+ + GS + +R+V+L +++ Sbjct: 3297 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355 Query: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287 G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN Sbjct: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415 Query: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345 N DP DDL GK V E P P T P Q++ G GV Sbjct: 3416 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 3469 Query: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405 + L P CH V P + C D CQ G C A+A Y AC AG L Sbjct: 3470 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 3525 Query: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465 + WR C C + Y C CP SC ++ E AC +GC C G + Sbjct: 3526 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 3583 Query: 466 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 501 CV +C C YP G S C TC + G Sbjct: 3584 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 3643 Query: 502 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557 C AV C +GD H+TTFDG R+ F TC Y+LA++ + F V +N Sbjct: 3644 LGC-VAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 3702 Query: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612 G + VQ + L + R+ D+ L P +IR Sbjct: 3703 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 3754 Query: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670 + + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G Sbjct: 3755 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 3811 Query: 671 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 719 FGNSW+ + SP + GS P D C L+ + C +L+ Sbjct: 3812 GNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTG 3871 Query: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776 + C + P + C D C G LC+ + Y C+ G V+ C Sbjct: 3872 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCP 3931 Query: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836 + C + Y C C C L++P C D C EGC C + QA Sbjct: 3932 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 3980 Query: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 893 CVP QC C+ GV Y P + + C C G V+ C +C GQV Sbjct: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 4031 Query: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953 C+ LS + PC HG C Sbjct: 4032 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 4052 Query: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011 P TC Q G C L +TC +GD HY +FDG FDF G C L Sbjct: 4053 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 4103 Query: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 1057 V + F+V +N N + + + +++ +G ++ + D+ G Sbjct: 4104 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 4163 Query: 1058 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1117 P S D + V + F + + +D V V + G + GLCGN Sbjct: 4164 ALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 4220 Query: 1118 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1169 D N+ P + +G SW A EC + C + L + Sbjct: 4221 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 4277 Query: 1170 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1226 C L S F CH V F+ C+ D C GGD + C ++++Y C Sbjct: 4278 GFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 4335 Query: 1227 GVAV-DWRTPRLCPYDC 1242 GV + DWR C C Sbjct: 4336 GVVIEDWRAQVGCEITC 4352 Score = 304 bits (778), Expect = 1e-81 Identities = 319/1217 (26%), Positives = 448/1217 (36%), Gaps = 193/1217 (15%) Query: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174 GG V PA C P Q + P + C+AWG H T DG + G Sbjct: 2038 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCE 2095 Query: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228 Y L H P ++F++ V N+ + GS + +R+V+L +++ Sbjct: 2096 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2154 Query: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287 G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN Sbjct: 2155 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 2214 Query: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345 N DP DDL GK V E P P T P Q++ G GV Sbjct: 2215 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2268 Query: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405 + L P CH V P + C D CQ G C A+A Y AC AG L Sbjct: 2269 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2324 Query: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465 + WR C C + Y C CP SC ++ E AC +GC C G + Sbjct: 2325 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 2382 Query: 466 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 501 CV +C C YP G S C TC + G Sbjct: 2383 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 2442 Query: 502 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557 C AV C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N Sbjct: 2443 LGC-VAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 2501 Query: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612 G + VQ + L + R+ D+ L P +IR Sbjct: 2502 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 2553 Query: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670 + + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G Sbjct: 2554 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 2610 Query: 671 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 719 FGNSW+ + SP + GS P + C L+ + C +L+ Sbjct: 2611 GNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTG 2670 Query: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776 + C + P + C D C G LC+ + Y C+ G V+ C Sbjct: 2671 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCP 2730 Query: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836 + C + Y C C C L++P C D C EGC C + QA Sbjct: 2731 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 2779 Query: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 893 CVP QC C+ G Y P + + C C G V+ C +C GQV Sbjct: 2780 CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 2830 Query: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953 C+ LS + PC HG C Sbjct: 2831 -------------CQPSGGILSCVNKDPC------------HGVTC-------------- 2851 Query: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011 P TC Q G C L +TC +GD HY +FDG FDF G C L Sbjct: 2852 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 2902 Query: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 1057 V + F+V +N N + + + +++ +G ++ + D+ G Sbjct: 2903 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962 Query: 1058 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1117 P S D + V + F + + +D V V + G + GLCGN Sbjct: 2963 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 3019 Query: 1118 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1169 D N+ P + +G SW A EC + C + L + Sbjct: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 3076 Query: 1170 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1226 C L F CH V F+ C+ D C GGD + C ++++Y C Sbjct: 3077 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 3134 Query: 1227 GVAV-DWRTPRLCPYDC 1242 GV + DWR C C Sbjct: 3135 GVVIEDWRAQVGCEITC 3151 Score = 298 bits (762), Expect = 7e-80 Identities = 305/1174 (25%), Positives = 450/1174 (38%), Gaps = 197/1174 (16%) Query: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199 P ++ C WG H +FDG + G +Y L P + F++ N + G Sbjct: 4069 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 4127 Query: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254 + + R V++ +G IH + +V G+ LP + R+ Q A ++ Sbjct: 4128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 4187 Query: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314 +++D V + + G GLCGN + +P +D V +G L + + SW+ Sbjct: 4188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 4247 Query: 315 EQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPF 369 AP P S P P L+Q G G + PF CHA+V P F Sbjct: 4248 --APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLSSGTGGPFTTCHAHVPPESF 4303 Query: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429 C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C Sbjct: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVC 4361 Query: 430 IACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPG 485 CPASC P + E CV+GC C G + CV C C +GT + G Sbjct: 4362 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421 Query: 486 SVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGDIH 520 S D C+ C C G C+ A C AEC GD H Sbjct: 4422 SEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPH 4481 Query: 521 FTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 575 + T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ ++ Sbjct: 4482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY- 4539 Query: 576 DPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLR 634 +TL+ L D + P+ D+ LS + V T G+ + +D + Sbjct: 4540 --NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF- 4596 Query: 635 LYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSG 692 + L+V + GLCG +N + DD + G P W+ A C VS Sbjct: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSK 4648 Query: 693 SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CL 748 PC Q + AC V+ T APC + P YF+ C DAC+ G P L Sbjct: 4649 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 4708 Query: 749 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 808 C +A Y C+ G + R C L C A Y C C +C L++PE C Sbjct: 4709 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC--- 4765 Query: 809 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCK 868 C EGC C D D CVP QC C G YP G+ P Sbjct: 4766 ------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG------- 4810 Query: 869 DGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCAC 928 C+ R P G V TC++ Sbjct: 4811 ---PECERRCECG--PGGHV-----------------TCQE------------------- 4829 Query: 929 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAY 988 G AC EEC + + CH C R C A Sbjct: 4830 -------GAACGPHEECRL----------EDGVQACHATGCGR-------------CLAN 4859 Query: 989 GDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR------- 1037 G HY T DG +D G+C L + D FS+++E ++G + R Sbjct: 4860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTVAG 4916 Query: 1038 KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTT 1097 + +S+ G + V + P + E +V + + LL+D Sbjct: 4917 QVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGDAH 4969 Query: 1098 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDTLD 1153 + + ++G+L GLCGNF+ ++ P ++ + FG++W A C + Sbjct: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 5029 Query: 1154 PR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209 P+ +C+ + + C L + F C V+ + ++ C+ D C+Q GD Sbjct: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKGDK 5087 Query: 1210 ECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242 C S++AY C GVAV WRT CP C Sbjct: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121 Score = 280 bits (716), Expect = 1e-74 Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%) Query: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186 A G RCQ+V E ++CRA G H TFDG Y + G SYT+V + Sbjct: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509 Query: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235 +FS++ N+ + SR VS +VG + + +T G R +LP Sbjct: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560 Query: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293 + RL+ Q +V + +D + + + GLCGN N DP D Sbjct: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620 Query: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351 D +T G L D VEF SW+ + L C P G + E Sbjct: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672 Query: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405 L PF CH + P PF C DLC G+ + CR L+ YA+AC + G + Sbjct: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732 Query: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464 WR+ C + C + Y C CP SC+ A+ + S CV+GC C G + Sbjct: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790 Query: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515 G CV + C C F G PG V D C CTC + + CPA CSV Sbjct: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850 Query: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555 +GD H+ +FDGRR+ F TC Y+L S F V ++N Sbjct: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910 Query: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614 G +Q + ++V V + + V G VL+ D + +P D ++ R Sbjct: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968 Query: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674 + VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G + Sbjct: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026 Query: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730 FGNSW +T C G D + S C +L F C + L P Sbjct: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085 Query: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788 C D C GQ LC LA YA C+ G V C LSC Y C Sbjct: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145 Query: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848 C +C DL P CG EC EGC C D + C+P C C Q Sbjct: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194 Query: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886 G +PPG + P G CHC++ G++SC+S + P AC P+G Sbjct: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239 Score = 254 bits (649), Expect = 9e-67 Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%) Query: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174 GG V PA C P Q + P + C+AWG H T DG + G Sbjct: 4440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 4497 Query: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228 Y L H P ++F++ V N+ + GS + +R+V+L +++ Sbjct: 4498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556 Query: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287 G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN Sbjct: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616 Query: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345 N DP DDL GK V E P P T P Q++ G GV Sbjct: 4617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 4670 Query: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405 + L P CH V P + C D CQ G C A+A Y AC AG L Sbjct: 4671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 4726 Query: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465 WR C + C + Y C CP SC ++ E AC +GC C G + Sbjct: 4727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 4784 Query: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500 CV +C C G YP PG + C C G Sbjct: 4785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 4844 Query: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556 C C C G IH+ T DGR Y +C Y+LA+ F++ L+ Sbjct: 4845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 4903 Query: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616 G + +L + V+L Q V + + +P ++ L Sbjct: 4904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 4954 Query: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676 + T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F Sbjct: 4955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 5011 Query: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731 G +W+ + G C V L + A Y S +AC L FA C A LSP Sbjct: 5012 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 5071 Query: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789 YF QC D C + + LC +LA Y C+ G+ V C L C A YS C Sbjct: 5072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 5131 Query: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849 C +C L+ C C EGC C D +L +Q +C+P C C G Sbjct: 5132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 5180 Query: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888 P S + S C C S AA CP G+V Sbjct: 5181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 5218 Score = 248 bits (634), Expect = 5e-65 Identities = 229/809 (28%), Positives = 327/809 (40%), Gaps = 102/809 (12%) Query: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199 P ++ C WG H +FDG + G +Y L P + F++ N + G Sbjct: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725 Query: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254 + + R V++ +G IH + +V G+ LP + R+ Q A ++ Sbjct: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 1785 Query: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314 +++D V + + G GLCGN + +P +D V +G L + + SW+ Sbjct: 1786 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845 Query: 315 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 365 AP P L C P + EQ E L P PF CHA+V Sbjct: 1846 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 1897 Query: 366 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 425 P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Sbjct: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 1955 Query: 426 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 481 Y C + CPASC P + E CV+GC C G + CV C C +GT Sbjct: 1956 YEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 2015 Query: 482 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 516 + GS D C+ C C G C+ A C AEC Sbjct: 2016 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 2075 Query: 517 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 571 GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ Sbjct: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 2134 Query: 572 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630 ++ +TL+ L D + P+ D+ LS + V T G+ + +D Sbjct: 2135 QIY---NHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191 Query: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 688 + + L+V + GLCG +N + DD + G P W+ A C Sbjct: 2192 DSF-VRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 2242 Query: 689 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 745 VS PC Q + AC V+ T APC + P YF+ C DAC+ G Sbjct: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302 Query: 746 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 804 P LC +A Y C+ G + R C C A Y C C +C L++PE Sbjct: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362 Query: 805 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG- 863 C C EGC C D D CVP QC C YP G + P G Sbjct: 2363 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411 Query: 864 --HCHCKD-GVMSCD--SRAPAAAC-PAG 886 C C++ G +SC+ S P C P+G Sbjct: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSG 2440 Score = 248 bits (634), Expect = 5e-65 Identities = 240/854 (28%), Positives = 339/854 (39%), Gaps = 115/854 (13%) Query: 105 CAPSY-LFSCFNGGECVHPAFC----DCRRFNATGPRCQMVYNAGPERDSICRAWGQHHV 159 C PS + SC N C H C C+ G P ++ C WG H Sbjct: 2831 CQPSGGILSCVNKDPC-HGVTCRPQETCKEQGGQGVCL-------PNYEATCWLWGDPHY 2882 Query: 160 ETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCGSSPYTCSRAVSLFFV 214 +FDG + G +Y L P + F++ N + G+ + R V++ + Sbjct: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-GNPAVSYVRVVTVAAL 2941 Query: 215 GEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVY 269 G IH + +V G+ LP + R+ Q A ++ +++D V Sbjct: 2942 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 3001 Query: 270 IKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSL 329 + + G GLCGN + +P +D V +G L + + SW+ AP P L Sbjct: 3002 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR--APGWDP------L 3053 Query: 330 PRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVSPLPFTASCTSDLCQS 380 C P + EQ E L P PF CHA+V P F C D+C Sbjct: 3054 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 3113 Query: 381 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC--- 437 GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C CPASC Sbjct: 3114 GGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVCGPPCPASCPSP 3171 Query: 438 HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPGSVVKED--CNT 494 P + E CV+GC C G + CV C C +GT + GS D C+ Sbjct: 3172 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 3231 Query: 495 -CTC--TSGKWECSTAVC--------------------PAECSVTGDIHFTTFDGRRYTF 531 C C G C+ A C AEC GD H+ T DG R+ F Sbjct: 3232 WCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDF 3291 Query: 532 PATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 586 TC+Y+L+ + FTVT+ N G +Q + +SV++ ++ +TL+ Sbjct: 3292 QGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY---NHSLTLSAR 3347 Query: 587 GD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645 L D + P+ D+ LS + V T G+ + +D + + L+V + Sbjct: 3348 WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF-VRLRVPAAYAG 3406 Query: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSGSPLDPCDVHLQ 703 GLCG +N + DD + G P W+ A C VS PC Q Sbjct: 3407 SLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSKPCPSPCTPEQQ 3458 Query: 704 AASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CLCATLAHYAHLC 759 + AC V+ T APC + P YF+ C DAC+ G P LC +A Y C Sbjct: 3459 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 3518 Query: 760 RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 819 + G + R C C A Y C C +C L++PE C C Sbjct: 3519 QAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC---------ESACR 3569 Query: 820 EGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG---HCHCKD-GVMSCD 875 EGC C D D CVP QC C YP G + P G C C++ G +SC+ Sbjct: 3570 EGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCE 3627 Query: 876 --SRAPAAAC-PAG 886 S P C P+G Sbjct: 3628 PSSCGPHETCRPSG 3641 Score = 161 bits (408), Expect = 8e-39 Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%) Query: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161 R +C P +C G C +CR + Q + G R C A G H T Sbjct: 4816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 4866 Query: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219 DG Y L G SY L V +P + FSI + + L V Q + Sbjct: 4867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 4919 Query: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277 LA+ +VT G V LP +G R+ ++++ L +DG + + + + Sbjct: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 4979 Query: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337 G GLCGN N + DD V +G V F +W+ ++ G P CL + Sbjct: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 5039 Query: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395 + E C L P PF C A +SP + C DLC GD A CR+LA Y Sbjct: 5040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 5098 Query: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455 AC AG ++ WRT C +HC + Y+ C C SC + C +GC Sbjct: 5099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 5156 Query: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510 C + + G C+ +C C +G P S++ DC+ C+C+S C A CP Sbjct: 5157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216 Query: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554 AE C ++ + TTFDG R + Y L+ T+ Sbjct: 5217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 5276 Query: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614 + ++V + VTLT V + +P + + R Sbjct: 5277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 5336 Query: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662 L VR GV+V G ++ + V G CG F+G+ +D+ Sbjct: 5337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383 Score = 115 bits (287), Expect = 8e-25 Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%) Query: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926 G+ D R+PA +CPA + C + +C + S R PC+ GC Sbjct: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780 Query: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983 C G + G AC C CT++G + PG +V + C C C + Q T S Sbjct: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840 Query: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017 TC GD HY +FDG FDF+G C LV S Sbjct: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900 Query: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068 +F V+VEN + S + + + + + V DD P D Sbjct: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958 Query: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128 +V +R G +V +T+ +D V + + L GLCGNF+ +++ Sbjct: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017 Query: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182 + N FG+SW P +P D L+ L ++ +K EC IL F Sbjct: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077 Query: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241 CH +D +C+ D C G C +++ YA C G V WR+ LCP Sbjct: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135 Query: 1242 C 1242 C Sbjct: 1136 C 1136 Score = 98.6 bits (244), Expect = 8e-20 Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%) Query: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022 C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV Sbjct: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513 Query: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073 +N + Y + R + +S+ G V D+ + P S + + V+ Sbjct: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573 Query: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133 + F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+ Sbjct: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630 Query: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186 + EF SSW + C D C + + C +L L F +CH Sbjct: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690 Query: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242 +D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C Sbjct: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745 Score = 92.4 bits (228), Expect = 6e-18 Identities = 116/501 (23%), Positives = 186/501 (37%), Gaps = 85/501 (16%) Query: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078 S P+LS EG A + + TCVP+ + C+ +G+ + + + Sbjct: 4755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 4810 Query: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125 P+ CG G G C P EC AC RC + ++T DG Sbjct: 4811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 4870 Query: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180 L Y+L+Q DE ++ + + +L L + +A QV Sbjct: 4871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 4919 Query: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240 ++VTVD + V PV+ R+ G ++ T +++ + + L++ S S Sbjct: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 4976 Query: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298 +G GLCG +G+ ++D L +GS E F +W+ P S G+ Sbjct: 4977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 5027 Query: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342 C C CL + AC + P+ + C+ + ++Y +Q Sbjct: 5028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087 Query: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398 C +L Y A C V ++ WR +CP C + S Y C C+ G+ G Sbjct: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 5146 Query: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457 C EGC C + +L + +CIP C CT + S S C Sbjct: 5147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERC 5198 Query: 2458 QHQCQAPDTIVPVDLGCPSPR 2478 C + + GCP R Sbjct: 5199 --SCSSSSGLTCQAAGCPPGR 5217 Score = 91.3 bits (225), Expect = 1e-17 Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%) Query: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093 GLA+A+ T A+ T + E C C GQ RC + Sbjct: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457 Query: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151 VGG C + E C D + TFDG + Y + + S D+ L ++ Sbjct: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514 Query: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208 K+ + G LV + +H V++ R V VD Q PVS R+ Sbjct: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572 Query: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268 +G ++ + + + L + ++ Q GLCG +GD A+D DG++ Sbjct: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629 Query: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315 A D F SW++ D C +C C R+ T Sbjct: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681 Query: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368 F+ CH + P F E + D V C L+ Y C + + + +WR C Sbjct: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741 Query: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426 P C ++S Y+ C AC P +C G P +C + EGCVC G + Sbjct: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792 Query: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461 C+P + C CT G+ A G E W L CQ +C Sbjct: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824 Score = 90.1 bits (222), Expect = 3e-17 Identities = 122/510 (23%), Positives = 186/510 (36%), Gaps = 84/510 (16%) Query: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123 C EG L+ S P A P G LG C + C+ S D + TFD Sbjct: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264 Query: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2183 G +Y+L+Q+ +H N+ N ++ + + +++ Sbjct: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324 Query: 2184 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2242 KVTV+ + PV +I + H ++ +D ++ + + V Sbjct: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384 Query: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP---D 2297 Q GLCG +GD +D +GS G A + F +SW+ VP S + T P D Sbjct: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDS-PCLPPTPCPPGSED 1440 Query: 2298 SCATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQ 2341 + C P L ++S+ T S+CH+ V P+ + I D + Sbjct: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500 Query: 2342 PCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQD 2393 C + YV+ C +E WR +CP C +S Y+ C C P CQD Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560 Query: 2394 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSL 2453 G EGC C G + + C+P +C C + GV E + L Sbjct: 1561 G------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVL 1601 Query: 2454 SGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLC 2511 C+ Q C A +V + C +P + L TKDP C Sbjct: 1602 IDNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------C 1645 Query: 2512 EGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541 G+ TCRP + C P+Y C Sbjct: 1646 HGV--TCRPQETCKEQGGQGVCLPNYEATC 1673 Score = 86.3 bits (212), Expect = 4e-16 Identities = 87/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%) Query: 920 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 972 GPC+ GC C G + D C L C C W Y F D S C G Sbjct: 3182 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 3240 Query: 973 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 1012 S CT C + C A+GD HY T DG FDF G C+ L Sbjct: 3241 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS 3300 Query: 1013 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 1059 +F+V V N + S + + +++ + N + D + Sbjct: 3301 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 3360 Query: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119 LD H + +V ++L +D + V ++ + G L GLCGN++ Sbjct: 3361 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 3417 Query: 1120 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1175 ++++ P ++ Q G + CP P +E F + + Sbjct: 3418 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 3469 Query: 1176 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1231 +S CH +V ++ CL D C G C +V+ Y C G + + Sbjct: 3470 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 3527 Query: 1232 WRTPRLCPYDC 1242 WR P CP+ C Sbjct: 3528 WRRPDFCPFQC 3538 Score = 85.9 bits (211), Expect = 5e-16 Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%) Query: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140 P CG + GL + G C P+ C + D +VT DG Y+LS Sbjct: 2045 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP 2101 Query: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194 C LG N F + + N VT+ +N +T+ + Sbjct: 2102 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2146 Query: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241 WP + F+++ H ++ + T S + + + S + + + Sbjct: 2147 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2201 Query: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294 A LCG+C D A+DL G VGGA+ + S PS T Q F Sbjct: 2202 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2260 Query: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349 PD+C + + + CH VPP + + + D VQ C A+ Y Sbjct: 2261 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2313 Query: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407 VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+ Sbjct: 2314 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 2367 Query: 2408 GEGCVCSEGTILHRRHSALCIPEAKCAC 2435 EGCVC G +L C+P +C C Sbjct: 2368 REGCVCDAGFVL---SGDTCVPVGQCGC 2392 Score = 85.9 bits (211), Expect = 5e-16 Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%) Query: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140 P CG + GL + G C P+ C + D +VT DG Y+LS Sbjct: 3246 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 3302 Query: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194 C LG N F + + N VT+ +N +T+ + Sbjct: 3303 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 3347 Query: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241 WP + F+++ H ++ + T S + + + S + + + Sbjct: 3348 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 3402 Query: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294 A LCG+C D A+DL G VGGA+ + S PS T Q F Sbjct: 3403 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 3461 Query: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349 PD+C + + + CH VPP + + + D VQ C A+ Y Sbjct: 3462 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 3514 Query: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407 VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+ Sbjct: 3515 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 3568 Query: 2408 GEGCVCSEGTILHRRHSALCIPEAKCAC 2435 EGCVC G +L C+P +C C Sbjct: 3569 REGCVCDAGFVL---SGDTCVPVGQCGC 3593 Score = 84.7 bits (208), Expect = 1e-15 Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%) Query: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140 P CG + GL + G C P+ C + D +VT DG Y+LS Sbjct: 4447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 4503 Query: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194 C LG N F + + N VT+ +N +T+ + Sbjct: 4504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 4548 Query: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241 WP + F+++ H ++ + T S + + + S + + + Sbjct: 4549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 4603 Query: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294 A LCG+C D A+DL G VGGA+ + S PS T Q F Sbjct: 4604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 4662 Query: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349 PD+C + + + CH VPP + + + D VQ C A+ Y Sbjct: 4663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 4715 Query: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407 VA C + EWRR D+CP C + S Y+ C +C P +C PE C+ Sbjct: 4716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 4769 Query: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462 EGCVC G +L C+P +C C G LGE + C+ +C+ Sbjct: 4770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 4818 Score = 84.3 bits (207), Expect = 2e-15 Identities = 86/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%) Query: 920 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 972 GPC+ GC C G + D C L C C W Y F D S C G Sbjct: 1981 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 2039 Query: 973 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 1012 S CT C + C A+GD HY T DG F+F G C+ L Sbjct: 2040 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLS 2099 Query: 1013 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 1059 +F+V V N + S + + +++ + N + D + Sbjct: 2100 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 2159 Query: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119 LD H + +V ++L +D + V ++ + G L GLCGN++ Sbjct: 2160 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 2216 Query: 1120 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1175 ++++ P ++ Q G + CP P +E F + + Sbjct: 2217 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 2268 Query: 1176 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1231 +S CH +V ++ CL D C G C +V+ Y C G + + Sbjct: 2269 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 2326 Query: 1232 WRTPRLCPYDC 1242 WR P CP+ C Sbjct: 2327 WRRPDFCPFQC 2337 Score = 83.6 bits (205), Expect = 3e-15 Identities = 131/574 (22%), Positives = 200/574 (34%), Gaps = 109/574 (18%) Query: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 2063 S P+LS EG A + + TCVP+ + C+ Sbjct: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 3613 Query: 2064 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2119 C EG + S P P G LG C + C+ S D + Sbjct: 3614 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 3662 Query: 2120 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2179 TFDG +Y+L+Q+ +H N+ N ++ + + Sbjct: 3663 TTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 3722 Query: 2180 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2238 +++ KVTV+ + PV +I + H ++ +D ++ + + V Sbjct: 3723 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782 Query: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2296 GLCG +GD +D +GS G A + F +SW+ VP S T P Sbjct: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPPT-CPP 3838 Query: 2297 DS--CATTD-CSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY--- 2338 S C +D C P L ++S+ T S+CH+ V P+ + I D Sbjct: 3839 GSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 3898 Query: 2339 -VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPK 2389 + C + YV+ C +E WR +CP C +S Y+ C C P Sbjct: 3899 NLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPL 3958 Query: 2390 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449 C DG EGC C G + + C+P +C C + GV E Sbjct: 3959 QCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPE 3999 Query: 2450 NSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2507 + L C+ Q C +V + C +P + L TKDP Sbjct: 4000 QTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVTKDP---------- 4046 Query: 2508 QTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541 C G+ TCRP + C P+Y C Sbjct: 4047 ---CHGV--TCRPQETCKEQGGQGVCLPNYEATC 4075 Score = 82.0 bits (201), Expect = 8e-15 Identities = 126/579 (21%), Positives = 197/579 (34%), Gaps = 119/579 (20%) Query: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 2063 S P+LS EG A + + TCVP+ + C+ Sbjct: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 2412 Query: 2064 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2119 C EG + S P P G LG C + C+ S D + Sbjct: 2413 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 2461 Query: 2120 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2179 TFDG +Y+L+Q+ +H N+ N ++ + + Sbjct: 2462 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 2521 Query: 2180 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2238 +++ KVTV+ + PV +I + H ++ +D ++ + + V Sbjct: 2522 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 2581 Query: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2296 GLCG +GD +D +GS G A + F +SW+ VP S P Sbjct: 2582 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPC------LPP 2632 Query: 2297 DSCA--------TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDT 2336 +C + +C P L ++S+ T S+CH+ V P+ + I D Sbjct: 2633 PTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 2692 Query: 2337 KY----VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC------ 2385 + C + YV+ C +E WR +CP C +S Y+ C C Sbjct: 2693 CLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSA 2752 Query: 2386 -EPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2444 P C DG EGC C G + + C+P +C C + A Sbjct: 2753 LSAPLQCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN----GA 2793 Query: 2445 LGETWNSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGT 2502 E + L C+ Q C +V + C +P + L KDP Sbjct: 2794 YYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVNKDP----- 2845 Query: 2503 VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541 C G+ TCRP + C P+Y C Sbjct: 2846 --------CHGV--TCRPQETCKEQGGQGVCLPNYEATC 2874 Score = 78.6 bits (192), Expect = 9e-14 Identities = 118/489 (24%), Positives = 165/489 (33%), Gaps = 103/489 (21%) Query: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112 A++ C R G +V Q CP G RC +V+ G C P C+ S Sbjct: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RC-----SVQNGLLGCYPDRFGTCQGS 867 Query: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172 D +V+FDG Y+L S + + P V++ Sbjct: 868 --GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRVLVEN 909 Query: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWLHSSG 2230 H Q + R V V+ + V V R G + D Y+ +D Q+Q Sbjct: 910 EHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGR 967 Query: 2231 LMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVGGAED 2272 +V +K + LCG+C +GD A+DL L+ G G A + Sbjct: 968 DAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---GQAAN 1024 Query: 2273 PAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSACHRF 2322 F +SWQ T G P C D ++ S F CH Sbjct: 1025 ALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSK 1081 Query: 2323 VPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCS 2373 + P+ +RD Y + C AL Y A C + WR + CP C Sbjct: 1082 LDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP 1137 Query: 2374 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433 S Y+AC C P +C D + C EGCVC EG L C+P A C Sbjct: 1138 PHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLPLASC 1189 Query: 2434 ACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGCPSPR 2478 C G G+T+ L C C + P LGC + Sbjct: 1190 GCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG 1248 Query: 2479 PESCLRFGE 2487 +C G+ Sbjct: 1249 SSTCQASGD 1257 Score = 67.0 bits (162), Expect = 3e-10 Identities = 113/432 (26%), Positives = 159/432 (36%), Gaps = 65/432 (15%) Query: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155 C P +E C ++ D + +FDG Y+L+ + + LT + K+ Sbjct: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722 Query: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2213 N G+ P V ++ + L ++I + KV V+ PVS RI T Sbjct: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGAS 1779 Query: 2214 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2271 L +D +Q + V+ + S G GLCG D + ND +G++ Sbjct: 1780 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 1833 Query: 2272 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2315 AP + W S + G D C + C C L + Sbjct: 1834 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888 Query: 2316 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2370 F+ CH VPPESF + + D C AL YVA C V IE WR C Sbjct: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948 Query: 2371 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2428 C +S Y+ C + C P +C PL P C+ EGC C G +L + C+ Sbjct: 1949 TCPENSHYEVCGSPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 2001 Query: 2429 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2487 P C C + A E W G C C+ G P SC GE Sbjct: 2002 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 2052 Query: 2488 VALLLPTKDPCC 2499 V LLP+ C Sbjct: 2053 VCGLLPSGQHGC 2064 Score = 67.0 bits (162), Expect = 3e-10 Identities = 126/501 (25%), Positives = 178/501 (35%), Gaps = 85/501 (16%) Query: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL---------GLAVRV--- 2096 T + Q C H+ G+++ + P P GIL G+ R Sbjct: 2800 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQET 2856 Query: 2097 -----GGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLT 2146 G C P +E C ++ D + +FDG Y+L+ + + LT Sbjct: 2857 CKEQGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLT 2914 Query: 2147 VHVLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGF 2204 + K+ N G+ P V ++ + L ++I + KV V+ PVS Sbjct: 2915 PFTVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 2971 Query: 2205 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLK 2262 RI T L +D +Q + V+ + S G GLCG D + ND Sbjct: 2972 RISVTQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030 Query: 2263 DGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC--------------- 2307 +G++ AP + W S + G D C + C C Sbjct: 3031 NGTL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCG 3080 Query: 2308 -LRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE- 2361 L + F+ CH VPPESF + + D C AL YVA C V IE Sbjct: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140 Query: 2362 WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTIL 2419 WR C C +S Y+ C C P +C PL P C+ EGC C G +L Sbjct: 3141 WRAQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL 3196 Query: 2420 HRRHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPR 2478 + C+P C C + A E W G C C+ G Sbjct: 3197 ---SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCT 3245 Query: 2479 PESCLRFGEVALLLPTKDPCC 2499 P SC GEV LLP+ C Sbjct: 3246 PASC-GLGEVCGLLPSGQHGC 3265 Score = 65.9 bits (159), Expect = 6e-10 Identities = 123/499 (24%), Positives = 174/499 (34%), Gaps = 81/499 (16%) Query: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVR--VGGDRCCPLWE 2106 T + Q C H+ G+++ + P P GIL + G C P Sbjct: 4001 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQET 4057 Query: 2107 CA-------------CRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVH 2148 C C ++ D + +FDG Y+L+ + + LT Sbjct: 4058 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 4117 Query: 2149 VLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRI 2206 + K+ N G+ P V ++ + L ++I + KV V+ PVS RI Sbjct: 4118 TVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 4174 Query: 2207 EDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDG 2264 L +D +Q + V+ + S G GLCG D + ND +G Sbjct: 4175 SVAQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233 Query: 2265 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------L 2308 ++ AP + W S + G D C + C C L Sbjct: 4234 TL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPL 4283 Query: 2309 RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WR 2363 + F+ CH VPPESF + + D C AL YVA C V IE WR Sbjct: 4284 SSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWR 4343 Query: 2364 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHR 2421 C C +S Y+ C C P +C PL P C+ EGC C G +L Sbjct: 4344 AQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL-- 4397 Query: 2422 RHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPE 2480 + C+P C C + A E W G C C+ G P Sbjct: 4398 -SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPA 4448 Query: 2481 SCLRFGEVALLLPTKDPCC 2499 SC GEV LLP+ C Sbjct: 4449 SC-GLGEVCGLLPSGQHGC 4466 Score = 32.7 bits (73), Expect = 5.4 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%) Query: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 940 CPA + C+ RTC+ LS C GC C L C Sbjct: 5121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 5169 Query: 941 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 973 ++C CT G+ Y P + S C C C S Sbjct: 5170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 5204 >gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein [Homo sapiens] Length = 1403 Score = 297 bits (761), Expect = 9e-80 Identities = 305/1178 (25%), Positives = 452/1178 (38%), Gaps = 205/1178 (17%) Query: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTL-----VGRHEPEGQSFSIQVHNDPQCG 199 P ++ C WG H +FDG + G +Y L +G F++ N+ + G Sbjct: 69 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR-G 127 Query: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254 + + R V++ +G IH + +V G+ LP + R+ Q A ++ Sbjct: 128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 187 Query: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314 +++D V + + G GLCGN + +P +D V +G L + + SW+ Sbjct: 188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 247 Query: 315 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 365 AP P L C P + EQ E L P PF CHA+V Sbjct: 248 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 299 Query: 366 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 425 P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Sbjct: 300 PESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 357 Query: 426 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 481 Y C CPASC P + E CV+GC C G + CV C C +GT Sbjct: 358 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 417 Query: 482 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 516 + GS D C+ C C G C+ A C AEC Sbjct: 418 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 477 Query: 517 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 571 GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ Sbjct: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 536 Query: 572 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630 ++ +TL+ L D + P+ D+ LS + V T G+ + +D Sbjct: 537 QIY---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593 Query: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 688 + + L+V + GLCG +N + DD + G P W+ A C Sbjct: 594 DSF-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 644 Query: 689 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 745 VS PC Q + AC V+ T APC + P YF+ C DAC+ G Sbjct: 645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704 Query: 746 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 804 P LC +A Y C+ G + R C L C A Y C C +C L++PE Sbjct: 705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764 Query: 805 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH 864 C C EGC C D D CVP QC C G YP G+ P Sbjct: 765 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG--- 810 Query: 865 CHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 924 C+ R P G V TC++ Sbjct: 811 -------PECERRCECG--PGGHV-----------------TCQE--------------- 829 Query: 925 GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCAST 984 G AC EEC + + CH C R Sbjct: 830 -----------GAACGPHEECRL----------EDGVQACHATGCGR------------- 855 Query: 985 CTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR--- 1037 C A G HY T DG +D G+C L + D FS+++E ++G + R Sbjct: 856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLV 912 Query: 1038 ----KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWD 1093 + +S+ G + V + P + E +V + + LL+D Sbjct: 913 TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFD 965 Query: 1094 QRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----AAVECP 1149 + + ++G+L GLCGNF+ ++ P ++ + FG++W ++ C Sbjct: 966 GDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCG 1025 Query: 1150 DTLDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQ 1205 + P+ +C+ + + C L + F C V+ + ++ C+ D C+Q Sbjct: 1026 EGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQ 1083 Query: 1206 GGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242 GD C S++AY C GVAV WRT CP C Sbjct: 1084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121 Score = 254 bits (649), Expect = 9e-67 Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%) Query: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174 GG V PA C P Q + P + C+AWG H T DG + G Sbjct: 440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 497 Query: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228 Y L H P ++F++ V N+ + GS + +R+V+L +++ Sbjct: 498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 556 Query: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287 G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN Sbjct: 557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 616 Query: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345 N DP DDL GK V E P P T P Q++ G GV Sbjct: 617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 670 Query: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405 + L P CH V P + C D CQ G C A+A Y AC AG L Sbjct: 671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 726 Query: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465 WR C + C + Y C CP SC ++ E AC +GC C G + Sbjct: 727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 784 Query: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500 CV +C C G YP PG + C C G Sbjct: 785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 844 Query: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556 C C C G IH+ T DGR Y +C Y+LA+ F++ L+ Sbjct: 845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 903 Query: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616 G + +L + V+L Q V + + +P ++ L Sbjct: 904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 954 Query: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676 + T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F Sbjct: 955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 1011 Query: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731 G +W+ + G C V L + A Y S +AC L FA C A LSP Sbjct: 1012 GAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071 Query: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789 YF QC D C + + LC +LA Y C+ G+ V C L C A YS C Sbjct: 1072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 1131 Query: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849 C +C L+ C C EGC C D +L +Q +C+P C C G Sbjct: 1132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 1180 Query: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888 P S + S C C S AA CP G+V Sbjct: 1181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 1218 Score = 161 bits (407), Expect = 1e-38 Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%) Query: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161 R +C P +C G C +CR + Q + G R C A G H T Sbjct: 816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 866 Query: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219 DG Y L G SY L V +P + FSI + + L V Q + Sbjct: 867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 919 Query: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277 LA+ +VT G V LP +G R+ ++++ L +DG + + + + Sbjct: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979 Query: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337 G GLCGN N + DD V +G V F +W+ ++ G P CL + Sbjct: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039 Query: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395 + E C L P PF C A +SP + C DLC GD A CR+LA Y Sbjct: 1040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 1098 Query: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455 AC AG ++ WRT C +HC + Y+ C C SC + C +GC Sbjct: 1099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156 Query: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510 C + + G C+ +C C +G P S++ DC+ C+C+S C A CP Sbjct: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216 Query: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554 AE C ++ + TTFDG R + Y L+ T+ Sbjct: 1217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 1276 Query: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614 + ++V + VTLT V + +P + + R Sbjct: 1277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 1336 Query: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662 L VR GV+V G ++ + V G CG F+G+ +D+ Sbjct: 1337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383 Score = 94.0 bits (232), Expect = 2e-18 Identities = 117/501 (23%), Positives = 187/501 (37%), Gaps = 85/501 (16%) Query: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078 S P+LS EG A + + TCVP+ + C+ +G+ + + + Sbjct: 755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 810 Query: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125 P+ CG G G C P EC AC RC + ++T DG Sbjct: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870 Query: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180 L Y+L+Q DE ++ + + +L L + +A QV Sbjct: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 919 Query: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240 ++VTVD + V PV+ R+ G ++ T +++ + + L++ S S Sbjct: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 976 Query: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298 +G GLCG +G+ ++D L +GS E F +W+VP S G+ Sbjct: 977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRVPGSSKGCGE------G 1027 Query: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342 C C CL + AC + P+ + C+ + ++Y +Q Sbjct: 1028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 1087 Query: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398 C +L Y A C V ++ WR +CP C + S Y C C+ G+ G Sbjct: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 1146 Query: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457 C EGC C + +L + +CIP C CT + S S C Sbjct: 1147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERC 1198 Query: 2458 QHQCQAPDTIVPVDLGCPSPR 2478 C + + GCP R Sbjct: 1199 --SCSSSSGLTCQAAGCPPGR 1217 Score = 84.7 bits (208), Expect = 1e-15 Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%) Query: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140 P CG + GL + G C P+ C + D +VT DG Y+LS Sbjct: 447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 503 Query: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194 C LG N F + + N VT+ +N +T+ + Sbjct: 504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 548 Query: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241 WP + F+++ H ++ + T S + + + S + + + Sbjct: 549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 603 Query: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294 A LCG+C D A+DL G VGGA+ + S PS T Q F Sbjct: 604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 662 Query: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349 PD+C + + + CH VPP + + + D VQ C A+ Y Sbjct: 663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 715 Query: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407 VA C + EWRR D+CP C + S Y+ C +C P +C PE C+ Sbjct: 716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 769 Query: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462 EGCVC G +L C+P +C C G LGE + C+ +C+ Sbjct: 770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 818 Score = 80.9 bits (198), Expect = 2e-14 Identities = 77/315 (24%), Positives = 117/315 (37%), Gaps = 43/315 (13%) Query: 963 PCHTCVC-------QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL---- 1011 PCH C ++G L +TC +GD HY +FDG FDF G C L Sbjct: 46 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105 Query: 1012 ---VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPS 1059 V + F+V +N N + + + +++ +G ++ + D+ G Sbjct: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165 Query: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119 P S D + V + F + + +D V V + G + GLCGN D Sbjct: 166 PVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDR 222 Query: 1120 KTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAKKE 1171 N+ P + +G SW A EC + C + L + Sbjct: 223 NPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGPGF 279 Query: 1172 CSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV 1228 C L F CH V F+ C+ D C GGD + C ++++Y C GV Sbjct: 280 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDHDILCKALASYVAACQAAGV 337 Query: 1229 AV-DWRTPRLCPYDC 1242 + DWR C C Sbjct: 338 VIEDWRAQVGCEITC 352 Score = 64.3 bits (155), Expect = 2e-09 Identities = 112/432 (25%), Positives = 157/432 (36%), Gaps = 65/432 (15%) Query: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155 C P +E C ++ D + +FDG Y+L+ + + LT + K+ Sbjct: 67 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNE 124 Query: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2213 N G+ P V ++ + L ++I + KV V+ PVS RI Sbjct: 125 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 181 Query: 2214 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2271 L +D +Q + V+ + S G GLCG D + ND +G++ Sbjct: 182 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 235 Query: 2272 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2315 AP + W S + G D C + C C L + Sbjct: 236 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 290 Query: 2316 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2370 F+ CH VPPESF + + D C AL YVA C V IE WR C Sbjct: 291 FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI 350 Query: 2371 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2428 C +S Y+ C C P +C PL P C+ EGC C G +L + C+ Sbjct: 351 TCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 403 Query: 2429 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2487 P C C + A E W G C C+ G P SC GE Sbjct: 404 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 454 Query: 2488 VALLLPTKDPCC 2499 V LLP+ C Sbjct: 455 VCGLLPSGQHGC 466 Score = 32.7 bits (73), Expect = 5.4 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%) Query: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 940 CPA + C+ RTC+ LS C GC C L C Sbjct: 1121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 1169 Query: 941 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 973 ++C CT G+ Y P + S C C C S Sbjct: 1170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 1204 >gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein [Homo sapiens] Length = 1472 Score = 280 bits (716), Expect = 1e-74 Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%) Query: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186 A G RCQ+V E ++CRA G H TFDG Y + G SYT+V + Sbjct: 511 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570 Query: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235 +FS++ N+ + SR VS +VG + + +T G R +LP Sbjct: 571 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621 Query: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293 + RL+ Q +V + +D + + + GLCGN N DP D Sbjct: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681 Query: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351 D +T G L D VEF SW+ + L C P G + E Sbjct: 682 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 733 Query: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405 L PF CH + P PF C DLC G+ + CR L+ YA+AC + G + Sbjct: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793 Query: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464 WR+ C + C + Y C CP SC+ A+ + S CV+GC C G + Sbjct: 794 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 851 Query: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515 G CV + C C F G PG V D C CTC + + CPA CSV Sbjct: 852 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 911 Query: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555 +GD H+ +FDGRR+ F TC Y+L S F V ++N Sbjct: 912 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 971 Query: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614 G +Q + ++V V + + V G VL+ D + +P D ++ R Sbjct: 972 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 1029 Query: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674 + VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G + Sbjct: 1030 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1087 Query: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730 FGNSW +T C G D + S C +L F C + L P Sbjct: 1088 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1146 Query: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788 C D C GQ LC LA YA C+ G V C LSC Y C Sbjct: 1147 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1206 Query: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848 C +C DL P CG EC EGC C D + C+P C C Q Sbjct: 1207 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1255 Query: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886 G +PPG + P G CHC++ G++SC+S + P AC P+G Sbjct: 1256 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1300 Score = 162 bits (409), Expect = 6e-39 Identities = 130/461 (28%), Positives = 184/461 (39%), Gaps = 49/461 (10%) Query: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177 H C ++ G RC + + P+R C+ G H +FDG + G +Y L Sbjct: 892 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 951 Query: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235 VG +F + V N+ + GS + +RAV V + + +A + G +V + Sbjct: 952 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 1006 Query: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286 V+ Q G V +VR T+ +D + V K+ GLCGN Sbjct: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066 Query: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346 N DP DDL G + + F +SWQE+ PG + P L Sbjct: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1123 Query: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404 +C L P PF CH+ + P C D C G C ALA YA AC AG Sbjct: 1124 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1183 Query: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464 + WR++ C + C + Y C CP SC C +GC C G Sbjct: 1184 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1241 Query: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509 C+ A C C GT +PPG C++ C C G C ++ C Sbjct: 1242 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301 Query: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKS 542 + C +GD H+TTFDGRR+ F TC Y+LA++ Sbjct: 1302 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1342 Score = 115 bits (287), Expect = 8e-25 Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%) Query: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926 G+ D R+PA +CPA + C + +C + S R PC+ GC Sbjct: 790 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 841 Query: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983 C G + G AC C CT++G + PG +V + C C C + Q T S Sbjct: 842 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 901 Query: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017 TC GD HY +FDG FDF+G C LV S Sbjct: 902 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961 Query: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068 +F V+VEN + S + + + + + V DD P D Sbjct: 962 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 1019 Query: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128 +V +R G +V +T+ +D V + + L GLCGNF+ +++ Sbjct: 1020 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078 Query: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182 + N FG+SW P +P D L+ L ++ +K EC IL F Sbjct: 1079 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138 Query: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241 CH +D +C+ D C G C +++ YA C G V WR+ LCP Sbjct: 1139 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1196 Query: 1242 C 1242 C Sbjct: 1197 C 1197 Score = 98.6 bits (244), Expect = 8e-20 Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%) Query: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022 C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV Sbjct: 516 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574 Query: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073 +N + Y + R + +S+ G V D+ + P S + + V+ Sbjct: 575 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 634 Query: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133 + F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+ Sbjct: 635 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 691 Query: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186 + EF SSW + C D C + + C +L L F +CH Sbjct: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 751 Query: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242 +D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C Sbjct: 752 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 806 Score = 91.3 bits (225), Expect = 1e-17 Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%) Query: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093 GLA+A+ T A+ T + E C C GQ RC + Sbjct: 480 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 518 Query: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151 VGG C + E C D + TFDG + Y + + S D+ L ++ Sbjct: 519 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 575 Query: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208 K+ + G LV + +H V++ R V VD Q PVS R+ Sbjct: 576 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633 Query: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268 +G ++ + + + L + ++ Q GLCG +GD A+D DG++ Sbjct: 634 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 690 Query: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315 A D F SW++ D C +C C R+ T Sbjct: 691 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 742 Query: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368 F+ CH + P F E + D V C L+ Y C + + + +WR C Sbjct: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802 Query: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426 P C ++S Y+ C AC P +C G P +C + EGCVC G + Sbjct: 803 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 853 Query: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461 C+P + C CT G+ A G E W L CQ +C Sbjct: 854 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 885 Score = 78.6 bits (192), Expect = 9e-14 Identities = 118/489 (24%), Positives = 165/489 (33%), Gaps = 103/489 (21%) Query: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112 A++ C R G +V Q CP G RC +V+ G C P C+ S Sbjct: 877 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RC-----SVQNGLLGCYPDRFGTCQGS 928 Query: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172 D +V+FDG Y+L S + + P V++ Sbjct: 929 --GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRVLVEN 970 Query: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWLHSSG 2230 H Q + R V V+ + V V R G + D Y+ +D Q+Q Sbjct: 971 EHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGR 1028 Query: 2231 LMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVGGAED 2272 +V +K + LCG+C +GD A+DL L+ G G A + Sbjct: 1029 DAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---GQAAN 1085 Query: 2273 PAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSACHRF 2322 F +SWQ T G P C D ++ S F CH Sbjct: 1086 ALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSK 1142 Query: 2323 VPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCS 2373 + P+ +RD Y + C AL Y A C + WR + CP C Sbjct: 1143 LDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP 1198 Query: 2374 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433 S Y+AC C P +C D + C EGCVC EG L C+P A C Sbjct: 1199 PHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLPLASC 1250 Query: 2434 ACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGCPSPR 2478 C G G+T+ L C C + P LGC + Sbjct: 1251 GCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG 1309 Query: 2479 PESCLRFGE 2487 +C G+ Sbjct: 1310 SSTCQASGD 1318 Score = 68.9 bits (167), Expect = 7e-11 Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 35/156 (22%) Query: 922 CLSGCACPQGLLRHGDACFLPEECPCTWKG------KEYFPGDQVMSPCHTCVCQRGSF- 974 C GC C +G G++C C C +G + ++PG S CH CQ G Sbjct: 1227 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH---CQEGGLV 1283 Query: 975 QCTLHPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 1015 C C +STC A GD HY TFDG FDF+G C V+++ T Sbjct: 1284 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC-VYVLAQT 1342 Query: 1016 SDV-----SFSVIVENVNCYSSGMICRKFISINVGN 1046 F+V+ ENV + + + I++ V N Sbjct: 1343 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVAN 1378 Score = 32.7 bits (73), Expect = 5.4 Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 11/77 (14%) Query: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123 C EG L+ S P A P G LG C + C+ S D + TFD Sbjct: 1277 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1325 Query: 2124 GSHVALFKEAIYILSQS 2140 G +Y+L+Q+ Sbjct: 1326 GRRFDFMGTCVYVLAQT 1342 >gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] Length = 1950 Score = 268 bits (686), Expect = 4e-71 Identities = 171/552 (30%), Positives = 262/552 (47%), Gaps = 43/552 (7%) Query: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGR-PLQGWRTQLRQC--TVHCKEKAFTYNEC 429 C + CQ+ +T C +E +R CA G + WR+ T C E+ Y EC Sbjct: 692 CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHI-YKEC 749 Query: 430 IACCPASCHPRASCVDSEIACVDGCYCPNGLIFED----GGCVAPAECPCEFHGTLYPPG 485 PA+C A DSE CV GC CP G + +D G CV AECPCE GT+Y PG Sbjct: 750 GPSNPATCSNVAPFQDSE--CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPG 807 Query: 486 SVVKEDCNT-CTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS 544 V + C + CTC KW C+ A+CP C V G TTFDG +Y FP C ++ + Sbjct: 808 EVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGS-SLTTFDGVKYNFPGNCHFLAVHNED 866 Query: 545 SGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDD 604 ++++++ PC Q G C+ SV+++L+ + + + D+ + Y D Sbjct: 867 ---WSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSD 923 Query: 605 AFEIRRLSSVFLRVRTNVGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFL 663 +I SS +L+V T V++ + ++LY+ + DTVGLCG++N +DDF+ Sbjct: 924 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 983 Query: 664 SPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFA 721 S + E T Q F NSW+ +S G+P C + ++ ++ + C +L + A Sbjct: 984 SSQNILEKTSQAFANSWEMMSC----PKGNP-SSC-ISIEKEKFAERHCGILLDSSGPLA 1037 Query: 722 PCSAFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLC-RRHGLPVDFRARLPACALS 778 C ++P PY E+C++ C C Q CLC L +Y C + V +R L C S Sbjct: 1038 SCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHS 1095 Query: 779 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837 C + + V C +C+ L+ + +C V+ D V+GC CP Y + + + C Sbjct: 1096 CPSGLVFKYNVKACNSSCRSLSERDRSCDVE-------DVPVDGCTCPDAMYQNNEGN-C 1147 Query: 838 VPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA--CPAGQVFVNCSDL 895 V ++QC C+ PG C C+DG++ C C G +V+CSD Sbjct: 1148 VLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSD- 1206 Query: 896 HTDLELSRERTC 907 + RTC Sbjct: 1207 -PKAQRRTNRTC 1217 Score = 126 bits (316), Expect = 4e-28 Identities = 103/403 (25%), Positives = 162/403 (40%), Gaps = 41/403 (10%) Query: 857 SDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSV 916 SD P D + C+++ CP ++ C S TC N++ Sbjct: 718 SDGPGTFESWRSDSDVVCETQR----CPEQHIYKECGP-------SNPATCS----NVAP 762 Query: 917 SARGPCLSGCACPQGLLRHG----DACFLPEECPCTWKGKEYFPGDQVMSPCHT-CVCQR 971 C+SGC CP+G L C L ECPC G Y PG+ PC + C CQ Sbjct: 763 FQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQD 822 Query: 972 GSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYS 1031 + CT C C G TFDG+ ++F G C L D S SV + Sbjct: 823 AKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHF-LAVHNEDWSISVELRPCPSGQ 880 Query: 1032 SGMICRKFISINVGNSL----IVFDDDSGNPSPES-----FLDDKQEVHTWRVGFFTLVH 1082 +G C +++ + +S+ VF+ D + + + DK ++ + + Sbjct: 881 TGT-CLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVET 939 Query: 1083 FPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSS 1142 + + + ++V P GLCG+++ K ++ + +N+ Q F +S Sbjct: 940 YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 999 Query: 1143 WAAVECPDTLDPRDMCVLNPLREPFAKKECSILL--SEVFEICHPVVDVTWFYSNCLTDT 1200 W + CP +P + +E FA++ C ILL S CHP+V+ ++ C T Sbjct: 1000 WEMMSCPKG-NPSSCISIE--KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYT 1056 Query: 1201 CGCSQGGDCECFCASVSAYAHQCCQ-HGVAVDWRTPRLCPYDC 1242 C C D C C + Y C + V WRT LC + C Sbjct: 1057 CTCENSQD--CLCTILGNYVKACAEKETYIVGWRT-GLCEHSC 1096 Score = 112 bits (281), Expect = 4e-24 Identities = 125/511 (24%), Positives = 179/511 (35%), Gaps = 97/511 (18%) Query: 105 CAPSYLFSCFNG-GECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRA--------W- 154 C YL G+CV A C C VY G R+ C + W Sbjct: 774 CPEGYLLDDIGEKGKCVLKAECPCESSGT-------VYQPGEVREGPCGSQCTCQDAKWS 826 Query: 155 -------GQHHVE-----TFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 202 G+ VE TFDG+ Y G + V + +SI V P Sbjct: 827 CTEALCPGRCKVEGSSLTTFDGVKYNFPGNCHFLAV-----HNEDWSISVELRPCPSGQT 881 Query: 203 YTCSRAVSLFF-----VGEQEIHLAKEVTHGGMRVQ-------LPHVMGSARLQQLAGYV 250 TC +V+L V + + VT+ +R Q + S+ Q+ Y Sbjct: 882 GTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYF 941 Query: 251 IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFV 310 V+ Q +Y+ M P T GLCG+ N +DD ++S L F Sbjct: 942 HVKLQIQIVPVMQ----LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFA 997 Query: 311 HSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRP--PFDACHA 362 +SW+ + C + NP + + ++ C LL P +CH Sbjct: 998 NSWEMMS----------------CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHP 1041 Query: 363 YVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE- 421 V+P P+ C C C L Y +ACA+ + GWRT L C C Sbjct: 1042 IVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSG 1099 Query: 422 KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLI-FEDGGCVAPAECPCEF 477 F YN + C +SC R D E VDGC CP+ + +G CV ++C C Sbjct: 1100 LVFKYN--VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 1157 Query: 478 HGTLYPPGSVVKEDCNTCTCTSG-----------KWECSTAVCPAECSVTGDIHFTTFDG 526 + + PG ++ D N C C G CS +CS T Sbjct: 1158 NDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTC 1217 Query: 527 RRYTFPATCQYILAKSRSSGTFTVTLQNAPC 557 P Y +GTF + ++ PC Sbjct: 1218 STRNIPVFDDYC---GHENGTFRILTESVPC 1245 Score = 105 bits (263), Expect = 5e-22 Identities = 51/142 (35%), Positives = 75/142 (52%), Gaps = 1/142 (0%) Query: 1106 WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLR 1164 +QG++ GLCGN + ++ T + + EFG+SW + EC DT+ C NP Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYC 1319 Query: 1165 EPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCC 1224 + +A ++C IL F CH VD + ++ C+ + C C G FC +V+ YA C Sbjct: 1320 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1379 Query: 1225 QHGVAVDWRTPRLCPYDCDFFN 1246 GV V WR P LCP CD++N Sbjct: 1380 AVGVCVSWRKPNLCPVYCDYYN 1401 Score = 105 bits (262), Expect = 7e-22 Identities = 76/246 (30%), Positives = 104/246 (42%), Gaps = 29/246 (11%) Query: 649 GLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYS 708 GLCG NG+ +DDF + S FGNSWKT CS V+ + PCD + +++ Sbjct: 1266 GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQT--FPCDSNPYCKAWA 1323 Query: 709 VQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQP----CLCATLAHYAHLCRRHGL 764 V+ C +L F C + P Y + C +AC C C +A YA C G+ Sbjct: 1324 VRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGV 1383 Query: 765 PVDFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDE 817 V +R + C + C E Y PC +TC+D G S Sbjct: 1384 CVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLV--------GQKFS--S 1432 Query: 818 CVEGC--ACPPDT-YLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH-CHCKDGVMS 873 +EGC CP YLD CV ++CSC + V P G + G C+C G + Sbjct: 1433 LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDV-IPAGGVIEDNCGRTCYCIAGQLE 1491 Query: 874 CDSRAP 879 C AP Sbjct: 1492 CSETAP 1497 Score = 99.0 bits (245), Expect = 6e-20 Identities = 74/239 (30%), Positives = 107/239 (44%), Gaps = 26/239 (10%) Query: 282 GLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGT 341 GLCGNNN D KDD T + +EF +SW+ +Q T + PC NP Sbjct: 1266 GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQECSDTVAQ--TFPC-DSNPYC 1319 Query: 342 MQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDVATWCRALAEYARACA 399 +CE L F CH V P + C + C G +C A+A YA AC+ Sbjct: 1320 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1379 Query: 400 QAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIACCPASCHPRASCVDSEI-ACVD 452 G WR + C V+C E + Y C +C + V + + ++ Sbjct: 1380 AVG-VCVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTC--KDQLVGQKFSSLLE 1435 Query: 453 GCY--CPNGLIFEDGG---CVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECS 505 GCY CP+ + D CV+ +EC C F+ + P G V++++C TC C +G+ ECS Sbjct: 1436 GCYAKCPDSAPYLDENTMKCVSLSECSC-FYNDVIPAGGVIEDNCGRTCYCIAGQLECS 1493 Score = 75.5 bits (184), Expect = 7e-13 Identities = 56/207 (27%), Positives = 89/207 (42%), Gaps = 26/207 (12%) Query: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS---CATT 2302 GLCG +GD +D T + SV GA + F +SW+ + F DS C Sbjct: 1266 GLCGNNNGDLKDDFTTRYSSVASGALE---FGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1322 Query: 2303 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-------KYVQQPCVALTVYVAMCHK 2355 C ++ + TF CH V P ++ ++ I + KY+ C A+ +Y C Sbjct: 1323 AVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF-CTAVAMYAEACSA 1380 Query: 2356 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEP-----PKTCQDGILGPLDPEHCQVLGEG 2410 VC+ WR+ + CP C + C EP KTC+D ++G + L EG Sbjct: 1381 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG----QKFSSLLEG 1436 Query: 2411 CV--CSEGTILHRRHSALCIPEAKCAC 2435 C C + ++ C+ ++C+C Sbjct: 1437 CYAKCPDSAPYLDENTMKCVSLSECSC 1463 Score = 67.4 bits (163), Expect = 2e-10 Identities = 122/529 (23%), Positives = 187/529 (35%), Gaps = 80/529 (15%) Query: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCP-TPQVLDEVTQRCVYLEDC--- 1463 C W Y+ C + +TC+D + + C CP + LDE T +CV L +C Sbjct: 1406 CRWHYEPCGTVTAKTCKD-QLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1464 Query: 1464 ---VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTAL 1520 V PA V + G T G S+ P S + T T L+ A +T Sbjct: 1465 YNDVIPAGGVIEDNCG-RTCYCIAGQLECSETAPTNSTFAVSTTTATTILSTGAAITLVT 1523 Query: 1521 NPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSS 1580 P TA P ++ ++TT GP P + G+T + + I T ++ Sbjct: 1524 GGPSTAASIPAITTSSSETT----------GTTLGPLTEPFTTGITETSVPIISTSGNAG 1573 Query: 1581 LPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1640 + + G A T V G+ + S R+ PR T AV G GS Sbjct: 1574 MTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA-GTPRVSGATPAV---GGGS-- 1627 Query: 1641 VRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS 1700 TP + A+ S S G+I+ SP +S A + S++G P+ Sbjct: 1628 ---TPGEAGPGATVSGSTGVSAGSITASPGAS---------ATSSESSKSGTTGPSVGGK 1675 Query: 1701 ASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1760 + S+ T + + S +T + ++ + G SP P P +P Sbjct: 1676 TGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTG-----SSPPGKLTRPSPGSP 1730 Query: 1761 PRPAQHTT------------------MATRSPALPPETPAAASLSTATDG---------- 1792 + TT + + ++ T A + + T G Sbjct: 1731 GHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTA 1790 Query: 1793 LAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVA----TPGPKASVITTPLQPQA 1848 ++ TP +S +T P S P + + G S T A + TP A Sbjct: 1791 VSGTPVVSPGAT-PGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAA 1849 Query: 1849 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSG 1897 +T T SPV T AA A + P GT G G + TSG Sbjct: 1850 ST----TSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKI-TSG 1893 Score = 49.7 bits (117), Expect = 4e-05 Identities = 91/424 (21%), Positives = 152/424 (35%), Gaps = 59/424 (13%) Query: 2047 TSTTCVPIAEQDCVRHI-CLEGQLIR-VNQSQHCPQGAAPPRCGILGLAVRVG------- 2097 T + P + +CV C EG L+ + + C A P C G + G Sbjct: 756 TCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP-CESSGTVYQPGEVREGPC 814 Query: 2098 GDRC--------CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHV 2149 G +C C C RC + S TFDG ++ + D ++V + Sbjct: 815 GSQCTCQDAKWSCTEALCPGRCKV-EGSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVEL 873 Query: 2150 LDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR--FNRKVTVDLQPVWPPVSRYGFRIE 2207 C S G CL + + L V +D+ FN TV + Y +I+ Sbjct: 874 RPCPSGQTGT------CLNSVTLL-LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQ 926 Query: 2208 --DTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLK 2262 + Y+ + +QIQ + L V GLCG + A +D Sbjct: 927 IFNASSSYLQVETYFHVKLQIQIVPVMQLY-VSMPPNQFTDTVGLCGSYNNKAEDDFMSS 985 Query: 2263 DGSVVGGAEDPAPFLDSWQV-------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT 2315 + ++ F +SW++ PSS S+ + +F C + + S+ Sbjct: 986 QNILEKTSQ---AFANSWEMMSCPKGNPSSCISIEKEKFAERHCG-------ILLDSSGP 1035 Query: 2316 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIEWRRSDYCPFL 2371 ++CH V P+ + E + T + C L YV C + I R+ C Sbjct: 1036 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHS 1095 Query: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2431 C S ++ V AC D E V +GC C + +++ + C+ ++ Sbjct: 1096 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV--DGCTCPDA--MYQNNEGNCVLKS 1151 Query: 2432 KCAC 2435 +C C Sbjct: 1152 QCDC 1155 Score = 42.7 bits (99), Expect = 0.005 Identities = 41/187 (21%), Positives = 71/187 (37%), Gaps = 49/187 (26%) Query: 882 ACPAGQVFVN----CSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD 937 +CP+G VF C+ L R+R+C+ + + + GC CP + ++ + Sbjct: 1095 SCPSGLVFKYNVKACNSSCRSLS-ERDRSCDVEDVPVD---------GCTCPDAMYQNNE 1144 Query: 938 A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQC------TLHPCAS------- 983 C L +C C + PG + + + CVC+ G C TL C+ Sbjct: 1145 GNCVLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDC 1204 Query: 984 --------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI 1035 T R+ FD D+ G + +F ++ E+V C G+ Sbjct: 1205 SDPKAQRRTNRTCSTRNIPVFD----DYCG---------HENGTFRILTESVPCCEDGLT 1251 Query: 1036 CRKFISI 1042 C + I + Sbjct: 1252 CSRKIIV 1258 >gi|134268640 tectorin alpha precursor [Homo sapiens] Length = 2155 Score = 237 bits (605), Expect = 1e-61 Identities = 210/797 (26%), Positives = 321/797 (40%), Gaps = 105/797 (13%) Query: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHND-PQCGSSPY 203 P+R+++C + TFDG Y + SYTL+ + I ++ P G + Sbjct: 707 PKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWL 766 Query: 204 TCSRAVSLFFVGEQEIHL----AKEVTHGGMRVQLP--HVMGSARLQQLAGYVIVRHQSA 257 R + V +QE+ + A EV G V+LP H G + + V + Sbjct: 767 RGLRIL----VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV 822 Query: 258 FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--E 315 T+ + +YI++S T GLCG NA+ D+ +GK TD++ F+ SW E Sbjct: 823 VTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFE 882 Query: 316 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY---EQCEALLRP---PFDACHAYVSPLPF 369 + N G + N + Y +C + P F CH V+ + Sbjct: 883 EICNGECGDLLKAC-------NNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935 Query: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429 +C LCQS G+ + C ++A YA AC A + WRT C + C E + + EC Sbjct: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRT-YDFCPLECPENSH-FEEC 993 Query: 430 IACCPASCHPRA---SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGS 486 I C +C CVDS C +GC C G CV +EC C F G Sbjct: 994 IT-CTETCETLTLGPICVDS---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNE 1049 Query: 487 V--VKEDCNT---CTCTSGKWECSTAVC-------------------PAECSVTGDIHFT 522 V DC C+ T + C T C A C V+G H+ Sbjct: 1050 TFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYL 1109 Query: 523 TFDGRRYTFPATCQYILA------KSRSSGTFTVTLQN------APCGLNQDGACVQSVS 570 TFDG + F +C IL S S F VT +N + Q V S Sbjct: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169 Query: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF-LRVRTNVGVRVLYD 629 +++H+ + V L + ++ P +I S F + V T+ G++V+YD Sbjct: 1170 IVIHRAYKHTV---------LVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220 Query: 630 REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 689 + L + V + T GLCG +NGN DD P+G+ S+ FG SW + Sbjct: 1221 WKTF-LSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQV 1279 Query: 690 VSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRRDACRCG--Q 745 G C ++ S Q CS++ + F+ C + ++P +++ C D+C G Sbjct: 1280 GCGDRCPSC-AKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAV 1338 Query: 746 PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEAC 805 C+ L +YA C+ G+ V +C ++C + Y CV+ C C + C Sbjct: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC 1398 Query: 806 GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP----GDSDIPS 861 CVEGC C L+ ++ C+ + C C+ G Y P +SD Sbjct: 1399 S---------HYCVEGCHCDAGYVLNGKS--CILPHSCGCYSDGKYYEPKQLFWNSDCTR 1447 Query: 862 LGHCHC-KDGVMSCDSR 877 C C + V+ CD R Sbjct: 1448 --RCRCFRRNVIQCDPR 1462 Score = 202 bits (513), Expect = 5e-51 Identities = 200/816 (24%), Positives = 318/816 (38%), Gaps = 78/816 (9%) Query: 113 CFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGK 172 C + ++ C + P+ + Y + E S C +G+ H TFDG ++ G Sbjct: 285 CLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGS 343 Query: 173 GSYTLVGRHEPEGQS---FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGG 229 +Y L+ R + S FS++ N+ + GS+ + + +S+ G + L + ++G Sbjct: 344 CAY-LLARQCLQTSSLPFFSVEAKNEHRRGSA-VSWVKELSVEVNGYKI--LIPKGSYGR 399 Query: 230 MRVQ-----LPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHG 282 ++V LP + G+ ++ Q V + +DG I + + T G Sbjct: 400 VKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCG 459 Query: 283 LCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTM 342 LCGN N +P DD + G+ V++ SW+ + S C Q + T Sbjct: 460 LCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK----CDSGCVDNCTQCDAAT- 514 Query: 343 QGVY---EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARA 397 + +Y + C L + P C V P F SC DLC + C+A+ YA Sbjct: 515 EALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALV 574 Query: 398 CAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYC 456 C G P+ WRTQ TV C + Y+ C + CP +C + + C +GC C Sbjct: 575 CQALGIPIGDWRTQTGCVSTVQCPSFSH-YSVCTSSCPDTCSDLTASRNCATPCTEGCEC 633 Query: 457 PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN---TCTCTSG-------KWECST 506 G + CV +C C+F G Y G N C C G K S Sbjct: 634 NQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSG 693 Query: 507 AVCPAE-------------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 553 VC E C ++ + TFDG Y FP+ Y L K+ + + Sbjct: 694 EVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEID 753 Query: 554 NAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPY-TDDAFEIRRLS 612 + A ++ + +++ D ++ A +V L Q +P + EI R + Sbjct: 754 INKKKPDAGPAWLRGLRILV-ADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR-N 811 Query: 613 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672 V + V V Y GL LY+++ + T GLCG +N N D+F P G Sbjct: 812 KNSTTVESKGVVTVQYSDIGL-LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870 Query: 673 PQLFGNSWKTLSACSPLVSGSPLDPC--DVHLQAASYSVQACSVL---TGEMFAPCSAFL 727 +F SW T G L C D L S C ++ + F C + Sbjct: 871 LAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVV 930 Query: 728 SPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEY 785 + Y+ C C+ G + LC ++A YA C+ + V C L C + + Sbjct: 931 NVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHF 990 Query: 786 SPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845 C+ C TC+ L C D C EGC C D CV R++C C Sbjct: 991 EECIT-CTETCETLTLGPIC---------VDSCSEGCQC--DEGYALLGSQCVTRSECGC 1038 Query: 846 HFQGVDYPPGDS---DIPSLGHCHCK--DGVMSCDS 876 +F+G ++ D+ C+C D + C++ Sbjct: 1039 NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCET 1074 Score = 182 bits (461), Expect = 6e-45 Identities = 185/718 (25%), Positives = 268/718 (37%), Gaps = 72/718 (10%) Query: 140 VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR-HEPEGQSFS---IQVHND 195 +Y D+ C G H TFDG + L P SF + N+ Sbjct: 1089 LYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNE 1148 Query: 196 PQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQ--QLAGYVI 251 + S + F IH A + V R+ LP +G ++ +V+ Sbjct: 1149 DRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV 1208 Query: 252 VRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 311 V + +D + + I + + T+GLCG N +P DDL G L V EF Sbjct: 1209 VETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQ 1268 Query: 312 SWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL--LRPPFDACHAYVSPLPF 369 SW ++ G P C + V + C + F CH+ V+P F Sbjct: 1269 SWVKRDTFCQVGCGDRC---PSCAKVEG--FSKVQQLCSLIPNQNAAFSKCHSKVNPTFF 1323 Query: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429 +C D C G V T C L YA C G + GWR CTV C + Y C Sbjct: 1324 YKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYT-SCTVTCPPNSH-YESC 1381 Query: 430 IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVV- 488 ++ C C D CV+GC+C G + C+ P C C G Y P + Sbjct: 1382 VSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW 1441 Query: 489 KEDCNT-CTC-TSGKWECSTAVCPAE-------------------CSVTGDIHFTTFDGR 527 DC C C +C C ++ C G F TFDG Sbjct: 1442 NSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGA 1501 Query: 528 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGL--NQDGACVQSVSVI---LHQDPRRQVT 582 FPA C ++L+ T L + L N D ++++I Q+ Sbjct: 1502 FLRFPANCAFVLS------TICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQIL 1555 Query: 583 LTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQR 642 + V + +P T A +I S FL + T+ +++ Y+ + + + + +R Sbjct: 1556 INDRNTVKVNGTQVNVPFITGLATKIYS-SEGFLVIDTSPDIQIYYNGFNV-IKISISER 1613 Query: 643 WVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT--------LSACSPLVSGSP 694 GLCG FNG+ DD+++ G P + + SWKT +C+ L Sbjct: 1614 LQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQY 1673 Query: 695 LDPCD-VHLQAASYSVQACSVLTG--EMFAPCSAFLSPVPYFEQCRRDACRCGQPC-LCA 750 CD VH+Q C LT F PC L P+P++E C D C + LC Sbjct: 1674 AAMCDNVHIQKMQ-GDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCG 1732 Query: 751 TLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV-APC-GRTCQDLASPEACG 806 +LA Y CR G+ C+ E PCV A C RTC+ E CG Sbjct: 1733 SLAAYGEACRSFGILSTEWIEKENCSGVVE-----DPCVGADCPNRTCELGNGRELCG 1785 Score = 134 bits (337), Expect = 1e-30 Identities = 119/454 (26%), Positives = 184/454 (40%), Gaps = 56/454 (12%) Query: 447 EIACVDGC-----YCPNGLIF-EDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT-- 498 EI +GC + G +F +D C C +F+ +Y C +C+ Sbjct: 253 EIDPANGCTSRGQFLRRGEVFWDDLNCTVKCRC-LDFNNEIY---------CQEASCSPY 302 Query: 499 -----SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFT 549 GK+ +AV + C V G+ H+ TFDG + F +C Y+LA+ + S F+ Sbjct: 303 EVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFS 362 Query: 550 VTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA--GDVLLFDQYKIIPPYTDDAFE 607 V +N ++ G+ V V + + ++ + + G V + D +P D Sbjct: 363 VEAKNE----HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTV 418 Query: 608 IRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVG 667 S + V T+ G+ V +D + + V ++ T GLCG +N N DDFL P G Sbjct: 419 KIYQSGISTAVETDFGLLVTFDGQHYAS-ISVPGSYINSTCGLCGNYNKNPLDDFLRPDG 477 Query: 668 VPESTPQLFGNSWKTLSACSPLVSG--SPLDPCDVHLQAASYSVQACSVL--TGEMFAPC 723 P + G SW+ A SG CD +A + C L T C Sbjct: 478 RPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWEC 537 Query: 724 SAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPV-DFRARLPACA-LSC 779 + P + C D C R LC + YA +C+ G+P+ D+R + + + C Sbjct: 538 GTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQC 597 Query: 780 EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVP 839 + YS C + C TC DL + C C EGC C L T CVP Sbjct: 598 PSFSHYSVCTSSCPDTCSDLTASRNCAT---------PCTEGCECNQGFVLSTSQ--CVP 646 Query: 840 RNQCSCHFQGVDYPPGD---SDIPSLGHCHCKDG 870 ++C C F G Y G+ + C C++G Sbjct: 647 LHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEG 680 Score = 112 bits (279), Expect = 7e-24 Identities = 104/403 (25%), Positives = 158/403 (39%), Gaps = 57/403 (14%) Query: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942 CP F C ++ TCE L L C GC C +G G C Sbjct: 984 CPENSHFEEC--------ITCTETCET--LTLGPICVDSCSEGCQCDEGYALLGSQCVTR 1033 Query: 943 EECPCTWKGKE-----------------YFPGDQVMSPCHTCVC--------QRGSFQCT 977 EC C ++G + Y G C T C + G + C Sbjct: 1034 SECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQ 1093 Query: 978 LHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVIVENVNCYS 1031 AS C G HY TFDG PFDF +C + L S S F V +N + Sbjct: 1094 ARTDAS-CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDP 1152 Query: 1032 SGMICRKFISINV-GNSLIV---FDDDSGNPSPESFLDDK---QEVHTWRVGFFTLVHFP 1084 S + K + + V G S+++ + S +L K +++ + GF +V Sbjct: 1153 SLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-T 1211 Query: 1085 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA 1144 + +++D +T + + Q GLCG ++ +++ P L ++ EFG SW Sbjct: 1212 DFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV 1271 Query: 1145 AVECPDTLDPRDMCVLNPLREPFAKKE--CSILLSE--VFEICHPVVDVTWFYSNCLTDT 1200 + + D C E F+K + CS++ ++ F CH V+ T+FY NCL D+ Sbjct: 1272 KRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331 Query: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242 C GG + C+ + YA C G+ V WR C C Sbjct: 1332 --CIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372 Score = 84.3 bits (207), Expect = 2e-15 Identities = 82/338 (24%), Positives = 128/338 (37%), Gaps = 27/338 (7%) Query: 924 SGCACPQGLLRHGDACF----LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 979 +GC LR G+ + +C C E + + SP C + F C+ Sbjct: 258 NGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAV 317 Query: 980 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS----FSVIVENVNCYSSGMI 1035 STC +G+ HY TFDG F F G+C L + S FSV +N + S + Sbjct: 318 E-TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVS 376 Query: 1036 CRKFISINV-GNSLIVFDDDSGNPSPESFLD------DKQEVHTWRVGFFTLVHFPQEHI 1088 K +S+ V G +++ G + D V ++ G T V + Sbjct: 377 WVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVE-TDFGL 435 Query: 1089 TLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----A 1144 + +D + + + GLCGN++ +++ P+ + + G SW A Sbjct: 436 LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495 Query: 1145 AVECPD-TLDPRDMCVLNPLREPFAKKECSILLSEVFEI--CHPVVDVTWFYSNCLTDTC 1201 +C +D C F C L + C VVD T F +C+ D C Sbjct: 496 DWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555 Query: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1238 G C ++ AYA C G+ + DWRT C Sbjct: 556 SVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGC 591 Score = 72.4 bits (176), Expect = 6e-12 Identities = 92/403 (22%), Positives = 142/403 (35%), Gaps = 58/403 (14%) Query: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942 CP+ + C+ D TC L S + PC GC C QG + C Sbjct: 597 CPSFSHYSVCTSSCPD-------TCSD--LTASRNCATPCTEGCECNQGFVLSTSQCVPL 647 Query: 943 EECPCTWKGKEYFPGDQVMSPCHT---CVCQRGS-FQCTLHPCAS--------------- 983 +C C + G Y G+ + + C+C+ G C C S Sbjct: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFP 707 Query: 984 ----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD-VSFSVIVENVNCYSSGMICRK 1038 C ++ TFDG + F L+K+ + + I N +G + Sbjct: 708 KRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLR 767 Query: 1039 FISINVGNSLIVFDDD-------SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1091 + I V + + +G F ++ +R T V + +T+ Sbjct: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE-SKGVVTVQ 826 Query: 1092 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVE---- 1147 + ++++ + GLCG ++ +E P N F SW E Sbjct: 827 YSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICN 886 Query: 1148 --CPDTLDP--RDMCVLNPLREPFAKKECSIL---LSEVFEICHPVVDVTWFYSNCLTDT 1200 C D L D +L R ++ C I+ + F CH VV+VT +Y CL Sbjct: 887 GECGDLLKACNNDSELLKFYR---SRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943 Query: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242 C GG+ C SV+ YA C V V WRT CP +C Sbjct: 944 --CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984 Score = 70.5 bits (171), Expect = 2e-11 Identities = 70/286 (24%), Positives = 114/286 (39%), Gaps = 30/286 (10%) Query: 2230 GLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2289 GL+ + S T GLCG + +A+++ L +G ++ A FL+SW + + Sbjct: 831 GLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCT---DNLAVFLESWTTFEEICN- 886 Query: 2290 GQTRFRPDSCATTD--------CSPC--LRMVSNRTFSACHRFVPPESFCELWI----RD 2335 G+ +C S C + SN +F CH V ++ + + Sbjct: 887 GECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQS 946 Query: 2336 TKYVQQPCVALTVYVAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG 2394 + C ++ Y + C V + WR D+CP C +S ++ C+T E TC+ Sbjct: 947 GGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTE---TCETL 1003 Query: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454 LGP+ + C EGC C EG L + C+ ++C C + G A ET+ L Sbjct: 1004 TLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGC-NFEGHQLATNETFWVDLD 1056 Query: 2455 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500 C D V + P E C+ G + D C+ Sbjct: 1057 CQIFCYCSGTDNRVHCET-IPCKDDEYCMEEGGLYYCQARTDASCI 1101 Score = 70.1 bits (170), Expect = 3e-11 Identities = 79/361 (21%), Positives = 128/361 (35%), Gaps = 49/361 (13%) Query: 922 CLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM-SPC-HTCVC-QRGSFQCTL 978 C+ GC C G + +G +C LP C C GK Y P S C C C +R QC Sbjct: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDP 1461 Query: 979 HPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHL---VKSTS 1016 C S C A G +RTFDG F C L + Sbjct: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521 Query: 1017 DVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVH 1071 D+SF +I+ + + + + I+ +D +G F+ Sbjct: 1522 DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI 1581 Query: 1072 TWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1131 GF + P I + ++ + + + Q ++ GLCGNF+ ++ T Sbjct: 1582 YSSEGFLVIDTSPD--IQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639 Query: 1132 ELTNPQEFGSSW---------AAVECPDTLDPR--DMCVLNPLREPFAKKECSIL--LSE 1178 + + SW A C + + MC +++ C L + Sbjct: 1640 PVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKG 1699 Query: 1179 VFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV-AVDWRTPRL 1237 F+ C+ ++D FY +C D C + C S++AY C G+ + +W Sbjct: 1700 FFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKEN 1756 Query: 1238 C 1238 C Sbjct: 1757 C 1757 Score = 68.2 bits (165), Expect = 1e-10 Identities = 81/368 (22%), Positives = 138/368 (37%), Gaps = 44/368 (11%) Query: 2170 LNMTHLAHQVTIDR-FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHS 2228 +++T + + I R + V V+ + ++ P+ +I + ++ +D ++ ++ Sbjct: 1161 VDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220 Query: 2229 -SGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLT 2287 + + ++ + +GLCG +G+ +DL + G + + F SW + Sbjct: 1221 WKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNE---FGQSWVKRDTFC 1277 Query: 2288 SVGQTRFRPDSCATTDCSPCLRMVS-----NRTFSACHRFVPPESFCELWIRDTKY---- 2338 VG P S ++ S N FS CH V P F + + D+ Sbjct: 1278 QVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGA 1337 Query: 2339 VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILG 2397 VQ C L Y + C + + WR C C +S Y++CV+ C+P C I Sbjct: 1338 VQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP--RCA-AIRL 1394 Query: 2398 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457 D H V EGC C G +L+ + CI C C WNS + C Sbjct: 1395 KSDCSHYCV--EGCHCDAGYVLNGKS---CILPHSCGCYSDGKYYEPKQLFWNSDCTRRC 1449 Query: 2458 Q-----------HQCQAPDTIVPVD--LGCPSPRPESCL--------RFGEVALLLPTKD 2496 + QC++ + + GC S + CL F L P Sbjct: 1450 RCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509 Query: 2497 PCCLGTVC 2504 L T+C Sbjct: 1510 AFVLSTIC 1517 Score = 53.9 bits (128), Expect = 2e-06 Identities = 65/277 (23%), Positives = 101/277 (36%), Gaps = 43/277 (15%) Query: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCS 2305 GLCG + + +D DG D +SW+V + ++ DS +C+ Sbjct: 459 GLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHA-------DWKCDSGCVDNCT 508 Query: 2306 PCLRMVSNRTFSA---------------CHRFVPPESFCELWIRDTKYVQQP----CVAL 2346 C F + C V P +F + D V+ C A+ Sbjct: 509 QCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAI 568 Query: 2347 TVYVAMCHKFHVCI-EWRRSDYC--PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEH 2403 Y +C + I +WR C C S S Y C ++C P TC D Sbjct: 569 QAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSC--PDTCSDLTASRNCATP 626 Query: 2404 CQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQA 2463 C EGC C++G +L ++ C+P KC C D G +GE + ++ + Q C+ Sbjct: 627 CT---EGCECNQGFVL---STSQCVPLHKCGC-DFDGHYYTMGEFFWATANCTVQCLCEE 679 Query: 2464 PDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500 + + C S E C P ++ CL Sbjct: 680 GGDVYCFNKTCGS--GEVCAVEDGYQGCFPKRETVCL 714 Score = 40.4 bits (93), Expect = 0.026 Identities = 69/305 (22%), Positives = 111/305 (36%), Gaps = 50/305 (16%) Query: 2119 FVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHL--- 2175 F TFDG+ + ++LS ++ + + W L +++ + Sbjct: 1495 FRTFDGAFLRFPANCAFVLSTICQKLPDISF----QLIINFDKWSAPNLTIISPVYFYIN 1550 Query: 2176 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2235 Q+ I+ N Q P ++ +I + +I T DIQI + +G +++ Sbjct: 1551 EEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYY---NGFNVIK 1607 Query: 2236 ASKTSKAQGH--GLCGICDGDAAND-LTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292 S + + Q GLCG +GD +D +TL+ VV SW+ T+ Q Sbjct: 1608 ISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSS----VVLAQSWK-----TNGMQK 1658 Query: 2293 RFRPDSCATTDCSP------------------CLRMVSNR-TFSACHRFVPPESFCELWI 2333 R SC S CL++ + F C+ + P F E Sbjct: 1659 RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCY 1718 Query: 2334 RDTKYVQ---QPCVALTVYVAMCHKFHV-CIEWRRSDYCPFLCSSDSTYQACVTACEPPK 2389 D Y Q C +L Y C F + EW + C S CV A P + Sbjct: 1719 LDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC-----SGVVEDPCVGADCPNR 1773 Query: 2390 TCQDG 2394 TC+ G Sbjct: 1774 TCELG 1778 >gi|16554449 zonadhesin isoform 3 [Homo sapiens] Length = 2812 Score = 230 bits (586), Expect = 2e-59 Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%) Query: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 206 C +G H TFDG ++ GK +Y L +P G S F + N+ Q G +C Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211 Query: 207 RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 263 V + + E + L K GG +V LP + +G +V ++ + + WD Sbjct: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270 Query: 264 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 323 G +Y+ +S G GLCGN + + +D + G D E +SWQ Sbjct: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330 Query: 324 PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 381 + P C +M G C L+ PF+ C +V F SC D+C Sbjct: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389 Query: 382 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 441 G C ++ C AG ++ WR + C + C + Y+ C CP +CH Sbjct: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447 Query: 442 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 493 S + CV+ C C G + C+ ++C C L+P GS K C Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502 Query: 494 TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 533 C C S W C A A C+ +GD H+ TFDG + F Sbjct: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562 Query: 534 TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 589 TC Y+L + SRS + F V+ N G + + +++V V + ++L + V Sbjct: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619 Query: 590 LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 649 +L +P + RLSS + + TN G++V YD L + + V + G Sbjct: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678 Query: 650 LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 706 LCG +N N+ DD L P G +WK + P LV G P C + A + Sbjct: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737 Query: 707 YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 762 ++ + C++L F+ C + P F C C + LC +L YA LC + Sbjct: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796 Query: 763 GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 822 G +R R C + C YSPC +PC TC + +P C C E C Sbjct: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848 Query: 823 ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 854 C L + CVP QC C Y P Sbjct: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878 Score = 224 bits (570), Expect = 1e-57 Identities = 218/885 (24%), Positives = 348/885 (39%), Gaps = 127/885 (14%) Query: 97 ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 134 +R + +C P ++ S C +C +HPA C C N Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512 Query: 135 PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180 RCQ +Y + + C A G H TFDG ++ G +Y L Sbjct: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571 Query: 181 HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 236 Q F + N+ + G + +AV + V + I L + +V G RV LP Sbjct: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630 Query: 237 VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 294 + R ++ + V++ + +DG+ V + + G GLCGN N + DD Sbjct: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690 Query: 295 LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 353 + KL D ++ +W+ ++P +P Q+N +M + + C L+ Sbjct: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746 Query: 354 RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411 P PF CH V P ASC C + GD CR+L YA CAQAG+ WR + Sbjct: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQ-APAWRNR 1805 Query: 412 LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 467 C + C + +Y+ C + CP +C +PR C + C + C C G I C Sbjct: 1806 -TFCPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DC-PKALPCAESCECQKGHILSGTSC 1861 Query: 468 VAPAECPC-EFHGTLYPPGS--VVKEDC-NTCTCT-SGKWECSTAVCPAE---------- 512 V +C C + G+ +P G + C CTC+ C + C Sbjct: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921 Query: 513 ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 559 C + G+ H+ +FDG ++ P C +L K + + F ++ ++ Sbjct: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981 Query: 560 NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 619 + + V + ++ QVTL + VL+ + +P + + SS++ V Sbjct: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038 Query: 620 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 679 +GV+V +D L L +++ + G+CG FN +D+ + P ++ F NS Sbjct: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097 Query: 680 WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 725 WK +C L+ P + L+ A +A L ++A C++ Sbjct: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEA--ALRAPVWAQCAS 2155 Query: 726 FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 783 + P+ C C G LC L + C+ GL C L C A Sbjct: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215 Query: 784 EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 841 Y+ C+ C +C DL DG + ++ C EGC C P L D CVPR+ Sbjct: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVL--SEDKCVPRS 2265 Query: 842 QCSC-HFQGVDYPPGDSDIPS--LGHCHCKDGVMSC-DSRAPAAA 882 QC C G P G S + S C C G + C D R P+ + Sbjct: 2266 QCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGS 2310 Score = 179 bits (454), Expect = 4e-44 Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%) Query: 407 GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 465 G T R T C A Y C CPASC PR SC C +GC C G +F D Sbjct: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085 Query: 466 GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 502 C+ + C C ++ Y PG+ E C C +G++ Sbjct: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145 Query: 503 ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 559 C A C V GD H+ TFDGR + F C YILA+ + T F VT +N G Sbjct: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204 Query: 560 NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 618 Q+G +C+ V V L P VTL + L+ Q +P + S F+ + Sbjct: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259 Query: 619 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 678 +T G+RV +D + +LY+ V + GLCG ++GN+ +D L G P + GN Sbjct: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318 Query: 679 SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 731 SW+T C V SP CD LQ++ C L T F C + Sbjct: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376 Query: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789 +F+ C D C + Q LC ++ C+ G V C ++C + +YS C Sbjct: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436 Query: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845 PC TC S C D CVE C C P L C+PR+QC C Sbjct: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481 Score = 164 bits (414), Expect = 2e-39 Identities = 201/850 (23%), Positives = 306/850 (36%), Gaps = 170/850 (20%) Query: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 206 +C+ G+ H +FDG + + + LV P F I H + G+ + Sbjct: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989 Query: 207 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 264 + + + V +V LP + + ++ + Y IV + + +DG Sbjct: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049 Query: 265 ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 324 + I++ G G+CGN N + +D+L+ S ++ + EFV+SW+++ + P Sbjct: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105 Query: 325 TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 372 + SL P Q+NP ++ E+CEA LR P A C + + PF Sbjct: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165 Query: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432 C + LC+ G C+AL + C G WR C + C + +Y C+ Sbjct: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223 Query: 433 CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 487 C SC C +++ AC +GC C G + + CV ++C C + HG P G S Sbjct: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283 Query: 488 VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 525 V C C CT G +C CP+ +CSV GD + TFD Sbjct: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343 Query: 526 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 583 G Y Y+L K T+ P G+ + V+ + + PR + L Sbjct: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390 Query: 584 -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632 QAG L+ + K+ PY R N +RV G Sbjct: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431 Query: 633 LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 674 RLYL D V GLCG ++ N ++D + P G Sbjct: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491 Query: 675 LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 715 FGNSW+ + A L +G + C Q AS S QAC VL Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550 Query: 716 TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRH------ 762 FA C ++P P+ E C D C P C L+ + R H Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYD 2610 Query: 763 -------------GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDG 809 GL R RL C P +A CG T + Sbjct: 2611 TLPSILCQPGRPRGLRGPLRGRLRQHPRLC-LQWHPEPPLADCGCTSNGIY------YQL 2663 Query: 810 GDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC--HFQGV--DYPPGDSDIPSLGHC 865 G ++C + C C L + C C+ H QG + P + + G C Sbjct: 2664 GSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQC 2723 Query: 866 HCKDGVMSCD 875 + +C+ Sbjct: 2724 REQGATFTCE 2733 Score = 151 bits (382), Expect = 8e-36 Identities = 234/1057 (22%), Positives = 367/1057 (34%), Gaps = 223/1057 (21%) Query: 1471 PTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEP 1530 PT T+P + PT S E+P + E P P+ +P + P P + + + Sbjct: 584 PTVPKEKPTIPTEK--PTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPT 641 Query: 1531 VVSPGPTQTTLQQPLELTASQLPAGPTESPASKGV-TASLLAIPHTP-ESSSLP-----V 1583 + S PT +T + P PTE P + T + + P P E S+P + Sbjct: 642 IPSEKPTIST----------EKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSI 691 Query: 1584 ALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT 1643 + PT M + T + T+ SP P P + P + Sbjct: 692 PTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKP 738 Query: 1644 TPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--A 1701 T P T P+ +P SP PT TP IS + PT+ + Sbjct: 739 TTPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPT 784 Query: 1702 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPP 1761 P+ P T T + + P +P E +STEK S PM P P S Sbjct: 785 EKPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV-- 833 Query: 1762 RPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPL 1821 + TT++T +P E P ++ST + T P++ + P ++P Sbjct: 834 ---EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPT 875 Query: 1822 AKVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPP 1879 K+ + T P + T + + T+P + T+SP P ++ P Sbjct: 876 EKL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP------- 920 Query: 1880 AAGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1938 T+PT +P E T S + T K I +++++PT Sbjct: 921 ------------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE----- 960 Query: 1939 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLA 1998 + T +T P P L +PT T P + + L P Sbjct: 961 -----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP-- 1003 Query: 1999 EAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA------------- 2045 H + LAA P S P S++ G ++TE Sbjct: 1004 --HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACP 1056 Query: 2046 ----NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQH 2077 + +C P+ + CV + C++ + N ++H Sbjct: 1057 ASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEH 1116 Query: 2078 C---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFK 2131 C P +CG + G C + C ++ D +VTFDG H Sbjct: 1117 CRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMG 1176 Query: 2132 EAIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK 2187 + YIL+Q S D V + + G CL + +T VT+ + R Sbjct: 1177 KCTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRT 1231 Query: 2188 VTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGL 2247 + Q P + G + +G + T ++++W + V S T + GL Sbjct: 1232 LVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGL 1290 Query: 2248 CGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP- 2306 CG DG++ ND DGS G E+ +SWQ Q +++ + + D S Sbjct: 1291 CGNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQ 1346 Query: 2307 --------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMC 2353 C R+V ++ F C V SF + + D Q C ++ C Sbjct: 1347 SSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTC 1406 Query: 2354 HKF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2412 H WR +CP C +S Y C C P TC G G + C E C Sbjct: 1407 QDAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACE 1461 Query: 2413 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449 C+ G +L CIP ++C C G +GE W Sbjct: 1462 CNPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495 Score = 108 bits (269), Expect = 1e-22 Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%) Query: 882 ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 941 ACP + C+ D TC + S R C+ C C G + G C Sbjct: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475 Query: 942 PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 981 +C C YF G++ P C CVC+ + +C C Sbjct: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535 Query: 982 ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 1028 A+TCTA GD HY TFDG F+G C L + + D F V N N Sbjct: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595 Query: 1029 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1086 Y + F +SI++ V + P + + R+ ++ + Sbjct: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652 Query: 1087 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1146 + + +D V V + GQL GLCGN++ ++++ P+ + + G++W Sbjct: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709 Query: 1147 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1196 + P++ +P C N + + + K C+IL++ F CH VV +++C Sbjct: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768 Query: 1197 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242 + CG GD C S+ AYA C Q G A WR CP C Sbjct: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812 Score = 107 bits (268), Expect = 1e-22 Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%) Query: 876 SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 935 SR+ CP + +C+ C + S C GC C G L Sbjct: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083 Query: 936 GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 974 + C C C + Y PG + SP C T VCQ + Sbjct: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143 Query: 975 QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 1029 Q HP A +TC YGD HY TFDG F F+G C L + +++D F V +N Sbjct: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203 Query: 1030 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085 G+ C + + + S + G + V G F + + Sbjct: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262 Query: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145 + + WD ++V + G+L GLCGN+D + N+ + + +E G+SW Sbjct: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322 Query: 1146 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1197 + D + V +P + + C L+ FE C V F+ +C+ Sbjct: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382 Query: 1198 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242 D CG G C +S C G AV WR P CP C Sbjct: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426 Score = 93.2 bits (230), Expect = 3e-18 Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%) Query: 2108 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2162 A C+ D ++TFDG+ Y+L S+S D V + + +++ Sbjct: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598 Query: 2163 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2207 C VMLN H+V + PVW R R+ Sbjct: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641 Query: 2208 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2265 + ++ ++ T +Q+++ G +VE + S G GLCG + ++ +D D Sbjct: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697 Query: 2266 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2318 + G D +W++P SS +P SC + C +++ + FS Sbjct: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754 Query: 2319 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2371 CH+ VPP+S + DT + C +L Y ++C + WR +CP Sbjct: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811 Query: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2431 C S+Y C + C P TC I P D E C C +G IL C+P Sbjct: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865 Query: 2432 KCACTDSMGVPRALGETW 2449 +C CTD G +GE W Sbjct: 1866 QCGCTDPAGSYHPVGERW 1883 Score = 80.5 bits (197), Expect = 2e-14 Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%) Query: 1465 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524 +P V + ++ E + PT E+P +S E P P+ +P + P+ T P Sbjct: 569 KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627 Query: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1582 TE+P + + T+ +++ P PTE P ++ T S+ E S+P Sbjct: 628 ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685 Query: 1583 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1637 + + PT M + T + T+ SP P P + Sbjct: 686 TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732 Query: 1638 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1694 P + T P T P+ +P S P + PT S + T T + +P Sbjct: 733 ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791 Query: 1695 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1745 S P+TP + E+ +P T E +STEK +P Sbjct: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851 Query: 1746 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1798 S P P P+ P P + T+ T P +P E T + L+ T+ +P Sbjct: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911 Query: 1799 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1844 ST + + P +T++ K + T P +P P S + Sbjct: 912 KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971 Query: 1845 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1902 + T+P + T+ P P A P H +P A G A L++ P++ + V Sbjct: 972 PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030 Query: 1903 EGTAS 1907 GT + Sbjct: 1031 LGTTT 1035 Score = 76.6 bits (187), Expect = 3e-13 Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%) Query: 883 CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 940 CP G + CS D ++ R C + L PC C C +G + G +C Sbjct: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862 Query: 941 LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 980 +C CT Y P + +TC C + FQ T P Sbjct: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922 Query: 981 CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 1018 C ++ C G+ HY +FDG AC + LVK Sbjct: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982 Query: 1019 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076 +F + ++ Y + + +K + + + + S P + ++G Sbjct: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042 Query: 1077 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1136 + + +D + ++ + G++ G+CGNF+ + +E+ P + + Sbjct: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091 Query: 1137 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1179 EF +SW + C L +P C LR A+++C + L + V Sbjct: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149 Query: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1238 + C +D+T F +C C GG + C ++ A+ C G+ WR C Sbjct: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207 Query: 1239 PYDCDFFN 1246 P +C ++ Sbjct: 2208 PLECPAYS 2215 Score = 76.3 bits (186), Expect = 4e-13 Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%) Query: 2178 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2236 QVT+ + +R + Q P +S+ G ++ + ++ +Q+++ + L+ +E Sbjct: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057 Query: 2237 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2292 T + G+CG + + ++L + V A + F++SW+ PS + + Sbjct: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114 Query: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2339 + P C R C + P + C I T ++ Sbjct: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174 Query: 2340 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2394 Q C AL + A C + WR S +CP C + S+Y C+ +C P DG Sbjct: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234 Query: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454 G P C EGC+C G +L C+P ++C C D+ G LG++W S S Sbjct: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286 Query: 2455 GCCQHQCQAPDTIVPVDLGCPS 2476 GC + I D CPS Sbjct: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308 Score = 75.1 bits (183), Expect = 9e-13 Identities = 93/442 (21%), Positives = 152/442 (34%), Gaps = 86/442 (19%) Query: 133 TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 185 +G CQ+ N ++ C +G TFDG Y L G+ +Y L+ + PEG Sbjct: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367 Query: 186 -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 244 + ++ N S ++ + + ++ E+ ++ +P+ Sbjct: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427 Query: 245 QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 301 L G Y++ + +++ G I + G GLCGN + + K+D++ SG Sbjct: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485 Query: 302 LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 345 LT ++ F +SW+ + + PR P ++ G G+ Sbjct: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540 Query: 346 ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYA-- 395 + C L P PF ACH V+P PF C DLC + C+ L+ + Sbjct: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVS 2600 Query: 396 -------------RACAQAGRP--LQG---------------WRTQLRQCTVHCKEKAFT 425 Q GRP L+G W + C Sbjct: 2601 SRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIY 2660 Query: 426 YNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG----GCVAPAEC---PCEFH 478 Y + C R +C S I + C G + G GC + C PC+ Sbjct: 2661 YQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQND 2720 Query: 479 GTLYPPGSVVKEDCNTCTCTSG 500 G G+ TC C G Sbjct: 2721 GQCREQGATF-----TCECEVG 2737 Score = 74.3 bits (181), Expect = 2e-12 Identities = 108/465 (23%), Positives = 172/465 (36%), Gaps = 95/465 (20%) Query: 1442 PVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL---------PTPS 1490 P PT + + +E+ V P +PTE T P+ + PT S Sbjct: 654 PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713 Query: 1491 DEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTAS 1550 E+P + E P PT + ++P P TT P TE+P +SP Sbjct: 714 PEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP---------------- 756 Query: 1551 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRVTVIFAGS 1609 + P PTE P ++ L IP E ++P T PT E T T Sbjct: 757 EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTPT------ 805 Query: 1610 PNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISR 1667 T+S+ P P + L T+ T T+ + +++ + P+ P + Sbjct: 806 EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPMEKPTISTE 855 Query: 1668 SPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRS 1727 PT + K ++P + + P+ LT+ T +P+ + Sbjct: 856 KPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEETTIST 896 Query: 1728 LEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETPAAA-- 1784 ++ + TEK +P S P +P+ P P + TT++T +P E P + Sbjct: 897 EKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953 Query: 1785 SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTP 1843 L+ T+ P +S E T P++ L+ ++P K P K + + P Sbjct: 954 KLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLTALRPP 1003 Query: 1844 -LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1881 P AT L A +SP P TP T + T PP A Sbjct: 1004 HPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048 Score = 70.9 bits (172), Expect = 2e-11 Identities = 90/382 (23%), Positives = 129/382 (33%), Gaps = 77/382 (20%) Query: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942 CPA + NC + + CE C GC C G + D C Sbjct: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCE------GAKVPSACAEGCICQPGYVLSEDKCVPR 2264 Query: 943 EECPC--TWKGKEYFPGDQVMSPC-HTCVCQRGSFQCTLHPCAS---------------- 983 +C C G V S C CVC G+ QC C S Sbjct: 2265 SQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCV 2324 Query: 984 -----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSV---IVENVNCYS---S 1032 C+ YGD Y TFDG + G L+K+ + V +VE N S Sbjct: 2325 SDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRS 2384 Query: 1033 GMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDDKQEVHTWRVGFFTLVHF 1083 + ++ I+ + G L+V + P P L V W + + F Sbjct: 2385 SIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL----RVTLWGQRLYLVTDF 2440 Query: 1084 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1143 + + + R + ++G ++GLCGN+D N+M P N FG+SW Sbjct: 2441 ---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSW 2497 Query: 1144 AAVECPDTL--DPRDMCVLNP-------LREPFAKKECS------------ILLSE---V 1179 V+ D L PR + LR ECS +L++ Sbjct: 2498 -EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGP 2556 Query: 1180 FEICHPVVDVTWFYSNCLTDTC 1201 F CH V F +C+ D C Sbjct: 2557 FAACHQTVAPEPFQEHCVLDLC 2578 Score = 49.7 bits (117), Expect = 4e-05 Identities = 119/546 (21%), Positives = 192/546 (35%), Gaps = 107/546 (19%) Query: 2026 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2079 +P+ ++G E + C P ++E CV C + + + Sbjct: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284 Query: 2080 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2124 +C G A++ G RC C +CS++ D ++TFDG Sbjct: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344 Query: 2125 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2180 L Y+L ++ D + V L + N PP + L T ++V Sbjct: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401 Query: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240 + V + + P R+ G ++T ++ + + +I S S Sbjct: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458 Query: 2241 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2285 +G GLCG D + ND+ L G++ ++ F +SW+V P+ Sbjct: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515 Query: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2333 G ++CSP ++ SN T F+ACH+ V PE F E + Sbjct: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574 Query: 2334 RDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQD 2393 D Q P + + V + S+ L S C+P + Sbjct: 2575 LDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPS---------ILCQPGR--PR 2623 Query: 2394 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCI------PEAKCACTDSMGVPRALGE 2447 G+ GPL G + R+H LC+ P A C CT S G+ LG Sbjct: 2624 GLRGPL---------------RGRL--RQHPRLCLQWHPEPPLADCGCT-SNGIYYQLG- 2664 Query: 2448 TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2507 +S L+ C +C + + L C P SC R GEV L C + C+ N Sbjct: 2665 --SSFLTEDCSQRCTCASSRI---LLC---EPFSC-RAGEVCTLGNHTQGCFPESPCLQN 2715 Query: 2508 QTLCEG 2513 +G Sbjct: 2716 PCQNDG 2721 Score = 32.7 bits (73), Expect = 5.4 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%) Query: 779 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837 C + Y C P +C+ SP +CG C EGC C P C Sbjct: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087 Query: 838 VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 870 + + C+C + Y PG HC C G Sbjct: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122 >gi|27881494 zonadhesin isoform 6 [Homo sapiens] Length = 2721 Score = 230 bits (586), Expect = 2e-59 Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%) Query: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 206 C +G H TFDG ++ GK +Y L +P G S F + N+ Q G +C Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211 Query: 207 RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 263 V + + E + L K GG +V LP + +G +V ++ + + WD Sbjct: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270 Query: 264 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 323 G +Y+ +S G GLCGN + + +D + G D E +SWQ Sbjct: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330 Query: 324 PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 381 + P C +M G C L+ PF+ C +V F SC D+C Sbjct: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389 Query: 382 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 441 G C ++ C AG ++ WR + C + C + Y+ C CP +CH Sbjct: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447 Query: 442 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 493 S + CV+ C C G + C+ ++C C L+P GS K C Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502 Query: 494 TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 533 C C S W C A A C+ +GD H+ TFDG + F Sbjct: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562 Query: 534 TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 589 TC Y+L + SRS + F V+ N G + + +++V V + ++L + V Sbjct: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619 Query: 590 LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 649 +L +P + RLSS + + TN G++V YD L + + V + G Sbjct: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678 Query: 650 LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 706 LCG +N N+ DD L P G +WK + P LV G P C + A + Sbjct: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737 Query: 707 YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 762 ++ + C++L F+ C + P F C C + LC +L YA LC + Sbjct: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796 Query: 763 GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 822 G +R R C + C YSPC +PC TC + +P C C E C Sbjct: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848 Query: 823 ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 854 C L + CVP QC C Y P Sbjct: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878 Score = 224 bits (570), Expect = 1e-57 Identities = 218/885 (24%), Positives = 348/885 (39%), Gaps = 127/885 (14%) Query: 97 ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 134 +R + +C P ++ S C +C +HPA C C N Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512 Query: 135 PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180 RCQ +Y + + C A G H TFDG ++ G +Y L Sbjct: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571 Query: 181 HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 236 Q F + N+ + G + +AV + V + I L + +V G RV LP Sbjct: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630 Query: 237 VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 294 + R ++ + V++ + +DG+ V + + G GLCGN N + DD Sbjct: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690 Query: 295 LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 353 + KL D ++ +W+ ++P +P Q+N +M + + C L+ Sbjct: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746 Query: 354 RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411 P PF CH V P ASC C + GD CR+L YA CAQAG+ WR + Sbjct: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQ-APAWRNR 1805 Query: 412 LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 467 C + C + +Y+ C + CP +C +PR C + C + C C G I C Sbjct: 1806 -TFCPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DC-PKALPCAESCECQKGHILSGTSC 1861 Query: 468 VAPAECPC-EFHGTLYPPGS--VVKEDC-NTCTCT-SGKWECSTAVCPAE---------- 512 V +C C + G+ +P G + C CTC+ C + C Sbjct: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921 Query: 513 ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 559 C + G+ H+ +FDG ++ P C +L K + + F ++ ++ Sbjct: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981 Query: 560 NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 619 + + V + ++ QVTL + VL+ + +P + + SS++ V Sbjct: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038 Query: 620 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 679 +GV+V +D L L +++ + G+CG FN +D+ + P ++ F NS Sbjct: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097 Query: 680 WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 725 WK +C L+ P + L+ A +A L ++A C++ Sbjct: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEA--ALRAPVWAQCAS 2155 Query: 726 FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 783 + P+ C C G LC L + C+ GL C L C A Sbjct: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215 Query: 784 EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 841 Y+ C+ C +C DL DG + ++ C EGC C P L D CVPR+ Sbjct: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVL--SEDKCVPRS 2265 Query: 842 QCSC-HFQGVDYPPGDSDIPS--LGHCHCKDGVMSC-DSRAPAAA 882 QC C G P G S + S C C G + C D R P+ + Sbjct: 2266 QCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGS 2310 Score = 179 bits (454), Expect = 4e-44 Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%) Query: 407 GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 465 G T R T C A Y C CPASC PR SC C +GC C G +F D Sbjct: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085 Query: 466 GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 502 C+ + C C ++ Y PG+ E C C +G++ Sbjct: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145 Query: 503 ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 559 C A C V GD H+ TFDGR + F C YILA+ + T F VT +N G Sbjct: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204 Query: 560 NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 618 Q+G +C+ V V L P VTL + L+ Q +P + S F+ + Sbjct: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259 Query: 619 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 678 +T G+RV +D + +LY+ V + GLCG ++GN+ +D L G P + GN Sbjct: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318 Query: 679 SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 731 SW+T C V SP CD LQ++ C L T F C + Sbjct: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376 Query: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789 +F+ C D C + Q LC ++ C+ G V C ++C + +YS C Sbjct: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436 Query: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845 PC TC S C D CVE C C P L C+PR+QC C Sbjct: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481 Score = 168 bits (426), Expect = 6e-41 Identities = 195/782 (24%), Positives = 295/782 (37%), Gaps = 156/782 (19%) Query: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 206 +C+ G+ H +FDG + + + LV P F I H + G+ + Sbjct: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989 Query: 207 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 264 + + + V +V LP + + ++ + Y IV + + +DG Sbjct: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049 Query: 265 ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 324 + I++ G G+CGN N + +D+L+ S ++ + EFV+SW+++ + P Sbjct: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105 Query: 325 TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 372 + SL P Q+NP ++ E+CEA LR P A C + + PF Sbjct: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165 Query: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432 C + LC+ G C+AL + C G WR C + C + +Y C+ Sbjct: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223 Query: 433 CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 487 C SC C +++ AC +GC C G + + CV ++C C + HG P G S Sbjct: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283 Query: 488 VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 525 V C C CT G +C CP+ +CSV GD + TFD Sbjct: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343 Query: 526 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 583 G Y Y+L K T+ P G+ + V+ + + PR + L Sbjct: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390 Query: 584 -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632 QAG L+ + K+ PY R N +RV G Sbjct: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431 Query: 633 LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 674 RLYL D V GLCG ++ N ++D + P G Sbjct: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491 Query: 675 LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 715 FGNSW+ + A L +G + C Q AS S QAC VL Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550 Query: 716 TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRHGLPV-D 767 FA C ++P P+ E C D C P C L+ YA LC+ G + Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610 Query: 768 FRARLPACALSCEASKEYSPCVA-PCGR--TCQDLASPEACGVDGGDDLSRDECVEGCAC 824 +R R CE SPC+ PC C++ + C + G C+E Sbjct: 2611 WRDR-----TLCE-----SPCLQNPCQNDGQCREQGATFTCECEVG--YGGGLCMEPRDA 2658 Query: 825 PP 826 PP Sbjct: 2659 PP 2660 Score = 151 bits (382), Expect = 8e-36 Identities = 234/1057 (22%), Positives = 367/1057 (34%), Gaps = 223/1057 (21%) Query: 1471 PTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEP 1530 PT T+P + PT S E+P + E P P+ +P + P P + + + Sbjct: 584 PTVPKEKPTIPTEK--PTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPT 641 Query: 1531 VVSPGPTQTTLQQPLELTASQLPAGPTESPASKGV-TASLLAIPHTP-ESSSLP-----V 1583 + S PT +T + P PTE P + T + + P P E S+P + Sbjct: 642 IPSEKPTIST----------EKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSI 691 Query: 1584 ALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT 1643 + PT M + T + T+ SP P P + P + Sbjct: 692 PTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKP 738 Query: 1644 TPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--A 1701 T P T P+ +P SP PT TP IS + PT+ + Sbjct: 739 TTPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPT 784 Query: 1702 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPP 1761 P+ P T T + + P +P E +STEK S PM P P S Sbjct: 785 EKPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV-- 833 Query: 1762 RPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPL 1821 + TT++T +P E P ++ST + T P++ + P ++P Sbjct: 834 ---EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPT 875 Query: 1822 AKVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPP 1879 K+ + T P + T + + T+P + T+SP P ++ P Sbjct: 876 EKL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP------- 920 Query: 1880 AAGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1938 T+PT +P E T S + T K I +++++PT Sbjct: 921 ------------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE----- 960 Query: 1939 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLA 1998 + T +T P P L +PT T P + + L P Sbjct: 961 -----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP-- 1003 Query: 1999 EAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA------------- 2045 H + LAA P S P S++ G ++TE Sbjct: 1004 --HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACP 1056 Query: 2046 ----NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQH 2077 + +C P+ + CV + C++ + N ++H Sbjct: 1057 ASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEH 1116 Query: 2078 C---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFK 2131 C P +CG + G C + C ++ D +VTFDG H Sbjct: 1117 CRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMG 1176 Query: 2132 EAIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK 2187 + YIL+Q S D V + + G CL + +T VT+ + R Sbjct: 1177 KCTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRT 1231 Query: 2188 VTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGL 2247 + Q P + G + +G + T ++++W + V S T + GL Sbjct: 1232 LVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGL 1290 Query: 2248 CGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP- 2306 CG DG++ ND DGS G E+ +SWQ Q +++ + + D S Sbjct: 1291 CGNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQ 1346 Query: 2307 --------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMC 2353 C R+V ++ F C V SF + + D Q C ++ C Sbjct: 1347 SSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTC 1406 Query: 2354 HKF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2412 H WR +CP C +S Y C C P TC G G + C E C Sbjct: 1407 QDAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACE 1461 Query: 2413 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449 C+ G +L CIP ++C C G +GE W Sbjct: 1462 CNPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495 Score = 108 bits (269), Expect = 1e-22 Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%) Query: 882 ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 941 ACP + C+ D TC + S R C+ C C G + G C Sbjct: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475 Query: 942 PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 981 +C C YF G++ P C CVC+ + +C C Sbjct: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535 Query: 982 ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 1028 A+TCTA GD HY TFDG F+G C L + + D F V N N Sbjct: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595 Query: 1029 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1086 Y + F +SI++ V + P + + R+ ++ + Sbjct: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652 Query: 1087 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1146 + + +D V V + GQL GLCGN++ ++++ P+ + + G++W Sbjct: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709 Query: 1147 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1196 + P++ +P C N + + + K C+IL++ F CH VV +++C Sbjct: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768 Query: 1197 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242 + CG GD C S+ AYA C Q G A WR CP C Sbjct: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812 Score = 107 bits (268), Expect = 1e-22 Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%) Query: 876 SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 935 SR+ CP + +C+ C + S C GC C G L Sbjct: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083 Query: 936 GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 974 + C C C + Y PG + SP C T VCQ + Sbjct: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143 Query: 975 QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 1029 Q HP A +TC YGD HY TFDG F F+G C L + +++D F V +N Sbjct: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203 Query: 1030 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085 G+ C + + + S + G + V G F + + Sbjct: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262 Query: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145 + + WD ++V + G+L GLCGN+D + N+ + + +E G+SW Sbjct: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322 Query: 1146 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1197 + D + V +P + + C L+ FE C V F+ +C+ Sbjct: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382 Query: 1198 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242 D CG G C +S C G AV WR P CP C Sbjct: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426 Score = 93.2 bits (230), Expect = 3e-18 Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%) Query: 2108 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2162 A C+ D ++TFDG+ Y+L S+S D V + + +++ Sbjct: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598 Query: 2163 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2207 C VMLN H+V + PVW R R+ Sbjct: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641 Query: 2208 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2265 + ++ ++ T +Q+++ G +VE + S G GLCG + ++ +D D Sbjct: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697 Query: 2266 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2318 + G D +W++P SS +P SC + C +++ + FS Sbjct: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754 Query: 2319 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2371 CH+ VPP+S + DT + C +L Y ++C + WR +CP Sbjct: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811 Query: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2431 C S+Y C + C P TC I P D E C C +G IL C+P Sbjct: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865 Query: 2432 KCACTDSMGVPRALGETW 2449 +C CTD G +GE W Sbjct: 1866 QCGCTDPAGSYHPVGERW 1883 Score = 86.3 bits (212), Expect = 4e-16 Identities = 86/377 (22%), Positives = 141/377 (37%), Gaps = 60/377 (15%) Query: 133 TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 185 +G CQ+ N ++ C +G TFDG Y L G+ +Y L+ + PEG Sbjct: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367 Query: 186 -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 244 + ++ N S ++ + + ++ E+ ++ +P+ Sbjct: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427 Query: 245 QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 301 L G Y++ + +++ G I + G GLCGN + + K+D++ SG Sbjct: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485 Query: 302 LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 345 LT ++ F +SW+ + + PR P ++ G G+ Sbjct: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540 Query: 346 ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYARA 397 + C L P PF ACH V+P PF C DLC + C+ L+ YA Sbjct: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAIL 2600 Query: 398 CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP 457 C +AG L GWR + C+ C C C E C C Sbjct: 2601 CQEAGAALAGWRDR-----TLCES---------PCLQNPCQNDGQC--REQGATFTCECE 2644 Query: 458 NGLIFEDGGCVAPAECP 474 G + G C+ P + P Sbjct: 2645 VG--YGGGLCMEPRDAP 2659 Score = 84.3 bits (207), Expect = 2e-15 Identities = 103/425 (24%), Positives = 146/425 (34%), Gaps = 79/425 (18%) Query: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942 CPA + NC + + CE C GC C G + D C Sbjct: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCE------GAKVPSACAEGCICQPGYVLSEDKCVPR 2264 Query: 943 EECPC--TWKGKEYFPGDQVMSPC-HTCVCQRGSFQCTLHPCAS---------------- 983 +C C G V S C CVC G+ QC C S Sbjct: 2265 SQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCV 2324 Query: 984 -----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSV---IVENVNCYS---S 1032 C+ YGD Y TFDG + G L+K+ + V +VE N S Sbjct: 2325 SDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRS 2384 Query: 1033 GMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDDKQEVHTWRVGFFTLVHF 1083 + ++ I+ + G L+V + P P L V W + + F Sbjct: 2385 SIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL----RVTLWGQRLYLVTDF 2440 Query: 1084 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1143 + + + R + ++G ++GLCGN+D N+M P N FG+SW Sbjct: 2441 ---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSW 2497 Query: 1144 AAVECPDTL--DPRDMCVLNP-------LREPFAKKECS------------ILLSE---V 1179 V+ D L PR + LR ECS +L++ Sbjct: 2498 -EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGP 2556 Query: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDC-ECFCASVSAYAHQCCQHGVAV-DWRTPRL 1237 F CH V F +C+ D C + E C +S YA C + G A+ WR L Sbjct: 2557 FAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTL 2616 Query: 1238 CPYDC 1242 C C Sbjct: 2617 CESPC 2621 Score = 80.5 bits (197), Expect = 2e-14 Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%) Query: 1465 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524 +P V + ++ E + PT E+P +S E P P+ +P + P+ T P Sbjct: 569 KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627 Query: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1582 TE+P + + T+ +++ P PTE P ++ T S+ E S+P Sbjct: 628 ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685 Query: 1583 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1637 + + PT M + T + T+ SP P P + Sbjct: 686 TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732 Query: 1638 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1694 P + T P T P+ +P S P + PT S + T T + +P Sbjct: 733 ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791 Query: 1695 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1745 S P+TP + E+ +P T E +STEK +P Sbjct: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851 Query: 1746 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1798 S P P P+ P P + T+ T P +P E T + L+ T+ +P Sbjct: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911 Query: 1799 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1844 ST + + P +T++ K + T P +P P S + Sbjct: 912 KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971 Query: 1845 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1902 + T+P + T+ P P A P H +P A G A L++ P++ + V Sbjct: 972 PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030 Query: 1903 EGTAS 1907 GT + Sbjct: 1031 LGTTT 1035 Score = 76.6 bits (187), Expect = 3e-13 Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%) Query: 883 CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 940 CP G + CS D ++ R C + L PC C C +G + G +C Sbjct: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862 Query: 941 LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 980 +C CT Y P + +TC C + FQ T P Sbjct: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922 Query: 981 CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 1018 C ++ C G+ HY +FDG AC + LVK Sbjct: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982 Query: 1019 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076 +F + ++ Y + + +K + + + + S P + ++G Sbjct: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042 Query: 1077 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1136 + + +D + ++ + G++ G+CGNF+ + +E+ P + + Sbjct: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091 Query: 1137 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1179 EF +SW + C L +P C LR A+++C + L + V Sbjct: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149 Query: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1238 + C +D+T F +C C GG + C ++ A+ C G+ WR C Sbjct: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207 Query: 1239 PYDCDFFN 1246 P +C ++ Sbjct: 2208 PLECPAYS 2215 Score = 76.3 bits (186), Expect = 4e-13 Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%) Query: 2178 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2236 QVT+ + +R + Q P +S+ G ++ + ++ +Q+++ + L+ +E Sbjct: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057 Query: 2237 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2292 T + G+CG + + ++L + V A + F++SW+ PS + + Sbjct: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114 Query: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2339 + P C R C + P + C I T ++ Sbjct: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174 Query: 2340 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2394 Q C AL + A C + WR S +CP C + S+Y C+ +C P DG Sbjct: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234 Query: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454 G P C EGC+C G +L C+P ++C C D+ G LG++W S S Sbjct: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286 Query: 2455 GCCQHQCQAPDTIVPVDLGCPS 2476 GC + I D CPS Sbjct: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308 Score = 74.3 bits (181), Expect = 2e-12 Identities = 108/465 (23%), Positives = 172/465 (36%), Gaps = 95/465 (20%) Query: 1442 PVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL---------PTPS 1490 P PT + + +E+ V P +PTE T P+ + PT S Sbjct: 654 PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713 Query: 1491 DEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTAS 1550 E+P + E P PT + ++P P TT P TE+P +SP Sbjct: 714 PEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP---------------- 756 Query: 1551 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRVTVIFAGS 1609 + P PTE P ++ L IP E ++P T PT E T T Sbjct: 757 EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTPT------ 805 Query: 1610 PNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISR 1667 T+S+ P P + L T+ T T+ + +++ + P+ P + Sbjct: 806 EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPMEKPTISTE 855 Query: 1668 SPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRS 1727 PT + K ++P + + P+ LT+ T +P+ + Sbjct: 856 KPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEETTIST 896 Query: 1728 LEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETPAAA-- 1784 ++ + TEK +P S P +P+ P P + TT++T +P E P + Sbjct: 897 EKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953 Query: 1785 SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTP 1843 L+ T+ P +S E T P++ L+ ++P K P K + + P Sbjct: 954 KLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLTALRPP 1003 Query: 1844 -LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1881 P AT L A +SP P TP T + T PP A Sbjct: 1004 HPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048 Score = 49.3 bits (116), Expect = 6e-05 Identities = 85/407 (20%), Positives = 143/407 (35%), Gaps = 70/407 (17%) Query: 2026 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2079 +P+ ++G E + C P ++E CV C + + + Sbjct: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284 Query: 2080 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2124 +C G A++ G RC C +CS++ D ++TFDG Sbjct: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344 Query: 2125 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2180 L Y+L ++ D + V L + N PP + L T ++V Sbjct: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401 Query: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240 + V + + P R+ G ++T ++ + + +I S S Sbjct: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458 Query: 2241 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2285 +G GLCG D + ND+ L G++ ++ F +SW+V P+ Sbjct: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515 Query: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2333 G ++CSP ++ SN T F+ACH+ V PE F E + Sbjct: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574 Query: 2334 RDTKYVQQP-------CVALTVYVAMCHKFHVCIE-WRRSDYCPFLC 2372 D Q P C L+ Y +C + + WR C C Sbjct: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621 Score = 32.7 bits (73), Expect = 5.4 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%) Query: 779 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837 C + Y C P +C+ SP +CG C EGC C P C Sbjct: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087 Query: 838 VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 870 + + C+C + Y PG HC C G Sbjct: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122 >gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] Length = 1503 Score = 160 bits (406), Expect = 1e-38 Identities = 133/430 (30%), Positives = 182/430 (42%), Gaps = 50/430 (11%) Query: 62 SSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCF-NGGECV 120 + S HQ +A G++ TV + S + + R +C+P SC + + Sbjct: 1083 TQSCVHQGREVASGERWTV-----DTCTSCSCMAGTVRCQSQRCSP---LSCGPDKAPAL 1134 Query: 121 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180 P C C PRC R + C A+G H TFDG + G SY L Sbjct: 1135 SPGSC-C-------PRCL-------PRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA-- 1177 Query: 181 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVM 238 + FS+ V ND + G S ++ V++ +G+ + L ++ VT G V LP + Sbjct: 1178 KDCHSGDFSVHVTNDDR-GRSGVAWTQEVAVL-LGDMAVRLLQDGAVTVDGHPVALPFLQ 1235 Query: 239 GSARLQQLAGYVIVRH-QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVT 297 +L G+ ++ H Q + WDG S V + + G T GLCGN N +DDL Sbjct: 1236 EPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQG 1295 Query: 298 SSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPF 357 G L F +SWQ P P ++ PC + +C L PF Sbjct: 1296 PEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPF 1355 Query: 358 DACHAYVSPLPFTASCTSDLCQ----SMGDVATWCRALAEYARACAQAGRPLQGWRTQLR 413 CHA V P PF A+C DLC S D A C AL YA C QAG WR Sbjct: 1356 SRCHAVVPPEPFFAACVYDLCACGPGSSAD-ACLCDALEAYASHCRQAG-VTPTWRGP-T 1412 Query: 414 QCTVHCK-EKAFTYNECIACCPASCHPR--------ASCVDSEIACVDGCYCPNGLIFED 464 C V C E+ F ++EC CP +C + A CV CV GC CP GL+ + Sbjct: 1413 LCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVR---PCVPGCQCPAGLVEHE 1469 Query: 465 GGCVAPAECP 474 C+ P CP Sbjct: 1470 AHCIPPEACP 1479 Score = 160 bits (405), Expect = 2e-38 Identities = 167/602 (27%), Positives = 229/602 (38%), Gaps = 118/602 (19%) Query: 726 FLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRA----RLPACALSCEA 781 F P E CR C+ GQ C L C+ L V R R C E Sbjct: 850 FEGPAGSCEWCR---CQAGQVS-CVRLQCPPLPCK---LQVTERGSCCPRCRGCLAHGEE 902 Query: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841 E S V P D A +G +R +C+ CA P D C P Sbjct: 903 HPEGSRWVPP------DSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD-----CCP-- 949 Query: 842 QCS-CHFQGVDYPPGDSDIPSLGHCH---CK---DGVMS--CDSR--------------- 877 QCS C +G Y PG+S P C C+ +G S C R Sbjct: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009 Query: 878 -APAAACPA-GQVFVNCSDLHTDLELSRERTCE----QQLLNLSVSARGPCLS------- 924 P CP + NCS+ EL+ C Q L L + P LS Sbjct: 1010 PGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERH 1069 Query: 925 ---GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ-VMSPCHTCVCQRGSFQCTLHP 980 G CP C P + C +G+E G++ + C +C C G+ +C Sbjct: 1070 TPPGSCCP--------VCRAPTQS-CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQR 1120 Query: 981 CA-------------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 1015 C+ ++C A+GD HYRTFDG F G+C L K Sbjct: 1121 CSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDC 1180 Query: 1016 SDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDS-----GNPSPESFLDDKQEV 1070 FSV V N + SG+ + +++ +G+ + D G+P FL + Sbjct: 1181 HSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLY 1240 Query: 1071 HTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPEN 1130 R G ++H Q + +LWD ++ V V +QG+ GLCGNF+ ++++ PE Sbjct: 1241 VELR-GHTVILH-AQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEG 1298 Query: 1131 LELTNPQEFGSSWAAVE---------CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFE 1181 L L + FG+SW E +DP RE A C +L S F Sbjct: 1299 LLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARRE--ANARCGVLKSSPFS 1356 Query: 1182 ICHPVVDVTWFYSNCLTDTCGCSQGGDCE-CFCASVSAYAHQCCQHGVAVDWRTPRLCPY 1240 CH VV F++ C+ D C C G + C C ++ AYA C Q GV WR P LC Sbjct: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVV 1416 Query: 1241 DC 1242 C Sbjct: 1417 GC 1418 Score = 159 bits (403), Expect = 3e-38 Identities = 141/474 (29%), Positives = 188/474 (39%), Gaps = 74/474 (15%) Query: 432 CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED 491 C +C P SC SE G CP C AP + C G G D Sbjct: 1053 CIHQAC-PELSCPLSERHTPPGSCCPV--------CRAPTQS-CVHQGREVASGERWTVD 1102 Query: 492 -CNTCTCTSGKWECSTAVC-------------------------PAECSVTGDIHFTTFD 525 C +C+C +G C + C PA C GD H+ TFD Sbjct: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162 Query: 526 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQ 585 GR F +C Y+LAK SG F+V + N G A Q V+V+L V L Q Sbjct: 1163 GRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRG-RSGVAWTQEVAVLLGD---MAVRLLQ 1218 Query: 586 AGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645 G V + D + + P+ + L + + G++VL+D + ++ + V + Sbjct: 1219 DGAVTV-DGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQS-QVEVSVPGSYQG 1276 Query: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT---LSACSPLVSGSPLDPCDVHL 702 T GLCG FNG QDD P G+ + FGNSW+ L P +G +DPC Sbjct: 1277 RTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPC---- 1332 Query: 703 QAASYSVQ-----ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCG-----QPCLCATL 752 +AA Y + C VL F+ C A + P P+F C D C CG CLC L Sbjct: 1333 RAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392 Query: 753 AHYAHLCRRHGLPVDFRARLPACALSC--EASKEYSPCVAPCGRTCQDLASPEACGVDGG 810 YA CR+ G+ +R C + C E + C PC RTC + P Sbjct: 1393 EAYASHCRQAGVTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLG------ 1445 Query: 811 DDLSRD---ECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 861 +L+ CV GC CP L C+P C D P G PS Sbjct: 1446 -ELAAHCVRPCVPGCQCPAG--LVEHEAHCIPPEACPQVLLTGDQPLGARPSPS 1496 Score = 84.3 bits (207), Expect = 2e-15 Identities = 113/404 (27%), Positives = 156/404 (38%), Gaps = 58/404 (14%) Query: 2059 CVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR---CSIFP 2115 C C+ G +R QSQ C +P CG A + CCP C R C F Sbjct: 1104 CTSCSCMAGT-VRC-QSQRC----SPLSCGP-DKAPALSPGSCCP--RCLPRPASCMAFG 1154 Query: 2116 DLSFVTFDGSHVALFKEAIYILSQSPDEM-LTVHVLDCKSANLGHLNWPPFCLVMLNMTH 2174 D + TFDG + Y+L++ +VHV + G + W V+L Sbjct: 1155 DPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSG-VAWTQEVAVLLG--D 1211 Query: 2175 LAHQVTIDRFNRKVTVDLQPVWPPVSRYGFR-IEDTGHMYMILTPSDIQIQWLHSSGLMI 2233 +A ++ D VTVD PV P + +E GH ++ +Q+ W G Sbjct: 1212 MAVRLLQDG---AVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW---DGQSQ 1265 Query: 2234 VEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL----- 2286 VE S QG GLCG +G A +DL +G ++ A F +SWQV L Sbjct: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLL---PSEAAFGNSWQVSEGLWPGRP 1322 Query: 2287 TSVGQTRFRPDSC------ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD----- 2335 S G+ D C A + + ++ + FS CH VPPE F + D Sbjct: 1323 CSAGR---EVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACG 1379 Query: 2336 --TKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDS--TYQACVTACEPPKTC 2391 + C AL Y + C + V WR C C + + C C P+TC Sbjct: 1380 PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPC--PRTC 1437 Query: 2392 --QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433 Q LG L + GC C G + H H CIP C Sbjct: 1438 FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAH---CIPPEAC 1478 Score = 58.5 bits (140), Expect = 9e-08 Identities = 66/231 (28%), Positives = 80/231 (34%), Gaps = 47/231 (20%) Query: 792 CGRTCQDLASPEACGVDGG------DDLSRDECVEGCA------CPPDTYLDTQADLCVP 839 C C D E VDG D C EG A CP C P Sbjct: 477 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP 536 Query: 840 RNQCSCHFQGVDYPPGDSDIPSLGH----CHCKDGVMSCDSRA------------PAAAC 883 + C F G +YP G +D P C C G + C +R P C Sbjct: 537 NDCSGCAFGGKEYPSG-ADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC 595 Query: 884 PAGQVFVNCSD------LHTDLELSRERTCEQQL-LNLSVSA-RGPCLSG-CACPQGLLR 934 P C H + C + L L+ SVS R PC CA P R Sbjct: 596 PQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP----R 651 Query: 935 HGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPCA 982 G C P C ++GKE+ G++ SP CH C+C GS C CA Sbjct: 652 QGPCC--PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACA 700 Score = 55.8 bits (133), Expect = 6e-07 Identities = 61/242 (25%), Positives = 84/242 (34%), Gaps = 55/242 (22%) Query: 787 PCVAPC---GRTCQDLASPEACGVDG-------------GDDLSRDECVEGCA------C 824 PC P G C +P C G GD R C++G C Sbjct: 583 PCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642 Query: 825 PPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSRAPAA 881 PP + C P C +QG ++ G+ CH C +G +SC+ +A A Sbjct: 643 PPAPCAHPRQGPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701 Query: 882 A----------CP-------AGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 924 A CP G+ +++ + E TC L R PC Sbjct: 702 ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTC---LGGFVTCGRRPCEP 758 Query: 925 -GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP----CHTCVCQRGSFQCTLH 979 GC+ P L+ G C P C + G G+ + P C C CQ GS +C Sbjct: 759 PGCSHP--LIPSGHCC--PTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKK 814 Query: 980 PC 981 PC Sbjct: 815 PC 816 Score = 50.8 bits (120), Expect = 2e-05 Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 39/182 (21%) Query: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838 C A +E PC A R ++ + CGV SR V PP+ + CV Sbjct: 1323 CSAGREVDPCRAAGYRARREANA--RCGVLKSSPFSRCHAV----VPPEPFFAA----CV 1372 Query: 839 PRNQCSCHFQGVDYPPGDS------DIPSLGHCHCKDGVMSCDSRAPA---AACPA--GQ 887 + C+C PG S D HC+ ++ R P CP G Sbjct: 1373 -YDLCACG-------PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGF 1424 Query: 888 VFVNCSDLHTDLELSRERTCEQQ---LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE 944 VF C RTC Q L L+ PC+ GC CP GL+ H C PE Sbjct: 1425 VFDECGP-------PCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEA 1477 Query: 945 CP 946 CP Sbjct: 1478 CP 1479 Score = 50.4 bits (119), Expect = 3e-05 Identities = 83/312 (26%), Positives = 106/312 (33%), Gaps = 72/312 (23%) Query: 691 SGSPL---DPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPC 747 SG P+ DPC H + A+ SVQ C L PC PVP CR GQ C Sbjct: 261 SGEPVGSGDPCS-HCRCANGSVQ-CEPL------PCP----PVP----CRHPGKIPGQCC 304 Query: 748 -LCATLAHYAHLCRRHGLPVDFRARLPACALSC-----EASKEYSPC-VAPCGRTCQDLA 800 +C + H ++ FR + + C E S E C V PC Sbjct: 305 PVCDGCEYQGH---QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ 361 Query: 801 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 860 AC +DG +E EG PD P C C +P Sbjct: 362 LCPACELDG------EEFAEGVQWEPDGR---------PCTACVCQ----------DGVP 396 Query: 861 SLGHCHCKDGVMSCDSRAPAAACPA-------GQVFVNCSDLHTDLELSRERTCEQQLLN 913 G C ++ P A CP+ QV+ N + TD + S C Q Sbjct: 397 KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNF-TDAD-SPCHACHCQDGT 454 Query: 914 LSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS----PCHTCVC 969 ++ S + CA PQ G C CP +E F + S PC C C Sbjct: 455 VTCSLVDCPPTTCARPQS--GPGQCC---PRCPDCILEEEVFVDGESFSHPRDPCQECRC 509 Query: 970 QRGSFQCTLHPC 981 Q G C PC Sbjct: 510 QEGHAHCQPRPC 521 Score = 48.1 bits (113), Expect = 1e-04 Identities = 53/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%) Query: 807 VDGGDDLSRDECVEGCA------CPPDTYLDTQADLCVPRNQC----SCHFQGVDYPPGD 856 V GD S C G CPP + + +P C C +QG Y + Sbjct: 265 VGSGDPCSHCRCANGSVQCEPLPCPP---VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQE 321 Query: 857 S-DIPSLG---HCHCKDGVMSCDSRAPAAACPAGQVFVNCS--DLHTDLELSRERTCEQQ 910 + + G C C+ G +SC+ + CP + S L EL E E Sbjct: 322 TFRLQERGLCVRCSCQAGEVSCEEQE----CPVTPCALPASGRQLCPACELDGEEFAE-- 375 Query: 911 LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECP---------------CTWKGKEYF 955 + G + C C G+ + G P C CT+ + Y Sbjct: 376 --GVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 433 Query: 956 PGDQVM---SPCHTCVCQRGSFQCTLHPCASTCTA 987 G SPCH C CQ G+ C+L C T A Sbjct: 434 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCA 468 Score = 46.2 bits (108), Expect = 5e-04 Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 17/128 (13%) Query: 865 CHCKDGVMSCDSRAPAAACPA----GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 920 C C+DG C +A C GQ + N D TC + L +V +G Sbjct: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT----TC--RCLTGAVQCQG 170 Query: 921 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCT 977 P S C + G+ C + C CT G + G + +P C C C G QC Sbjct: 171 PSCSELNCLESCTPPGECCPI---C-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 226 Query: 978 LHPCASTC 985 CAS C Sbjct: 227 QRECASLC 234 Score = 44.7 bits (104), Expect = 0.001 Identities = 92/389 (23%), Positives = 121/389 (31%), Gaps = 116/389 (29%) Query: 2398 PLDPEHCQVLGEGCVCSEGTILHRRHS---ALCIPEAK-------CACTDSMGVPRALGE 2447 PLDP C + C C EG++ ++ ALC + C S G GE Sbjct: 794 PLDPT-CSL----CTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE 848 Query: 2448 TWNSSLSGCCQHQCQAPDTIVPVDLGCPS--------------PRPESCLRFGEV----A 2489 + C +CQA + V L CP PR CL GE + Sbjct: 849 EFEGPAGSCEWCRCQAGQ-VSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907 Query: 2490 LLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYS----------- 2538 +P C + CVC++ + C D CCP S Sbjct: 908 RWVPPDSAC---SSCVCHEGVVTCARIQCISSCAQPRQGPHD-CCPQCSDCEHEGRKYEP 963 Query: 2539 -------------CECDPD-------LCEAELVPS---CRQDQILITGRLGDSCCTSYFC 2575 C C+P C PS C Q+L G CC + Sbjct: 964 GESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGP--QHCCPTCAE 1021 Query: 2576 ACGDCPDSIP-------------ECQEGEALTVHRNTTELCCPLYQ------CVCENFRC 2616 A +C + + +CQ+ L +H+ EL CPL + C R Sbjct: 1022 ALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRA 1081 Query: 2617 PQVQC---GLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV 2673 P C G A E W+ D C SC C T+ RC S L Sbjct: 1082 PTQSCVHQGREVASGERWTVDTC---TSCSCMAGTV---RCQSQRCSPLS---------- 1125 Query: 2674 CGCAKYECVK----APVCLSRELGVMQPG 2698 CG K + P CL R M G Sbjct: 1126 CGPDKAPALSPGSCCPRCLPRPASCMAFG 1154 Score = 42.0 bits (97), Expect = 0.009 Identities = 130/604 (21%), Positives = 178/604 (29%), Gaps = 164/604 (27%) Query: 2296 PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHK 2355 P +C DCS C + + + F P C L + VQ C+A C + Sbjct: 531 PGTCCPNDCSGCA--FGGKEYPSGADFPHPSDPCRLCRCLSGNVQ--CLARRCVPLPCPE 586 Query: 2356 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTC-QDGILGPLDPEHCQVLGEGC--- 2411 P L + C C P C + G E+ G+ C Sbjct: 587 -------------PVLLPGE-----CCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRC 628 Query: 2412 VCSEGTILHRRHSALCIPEAKCA------CTDS------MGVPRALGETWNSSLSGCCQH 2459 +C +G++ +R L P A CA C S G A GE + S + C H Sbjct: 629 LCLDGSVSCQR---LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAAC--H 683 Query: 2460 QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCC--------LGTVCVCNQTLC 2511 C + G S P++C P + CC LG + NQ Sbjct: 684 LCLCWE-------GSVSCEPKAC---APALCPFPARGDCCPDCDGCEYLGESYLSNQEF- 732 Query: 2512 EGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCT 2571 P R L T C CE P C L+PS CC Sbjct: 733 ----PDPREPCNLCTCLGGFVTCGRRPCE--PPGCSHPLIPS-------------GHCCP 773 Query: 2572 SYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVW 2631 + C C GE L + T C L C + RC + C Sbjct: 774 T----CQGCRYHGVTTASGETLPDPLDPT---CSLCTCQEGSMRCQKKPC---------- 816 Query: 2632 SPDRCCPYKSC-ECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCG-------------CA 2677 P CP+ S C C P CH + + E G C Sbjct: 817 -PPALCPHPSPGPCFC-----PVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870 Query: 2678 KYECVKAPV---------CLSRELGVMQPGQTVVELSA----DGVCHTSRCTTVLDPLTN 2724 + +C P C R G + G+ E S D C + C + Sbjct: 871 RLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGV----- 925 Query: 2725 FYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIAD 2784 + + C C Q + P D C C + + F PGA Sbjct: 926 ---VTCARIQCISSCA--QPRQGPHDCCPQCSDCEHEGRKYE----PGESFQPGADPCEV 976 Query: 2785 CARHHCSSTPLGAVLVR-------SPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGR 2837 C C P G +R S + CPP + P + CC TC E Sbjct: 977 CI---CEPQPEGPPSLRCHRRQCPSLVGCPPSQ---------LLPPGPQHCCPTCAEALS 1024 Query: 2838 SCKK 2841 +C + Sbjct: 1025 NCSE 1028 Score = 42.0 bits (97), Expect = 0.009 Identities = 66/278 (23%), Positives = 89/278 (32%), Gaps = 50/278 (17%) Query: 731 PYFEQCRRDACRCGQ------PCLCATLAH--------YAHLCRRHGLPVDFRARLPACA 776 P + CRR C G PC A AH C G R P+ Sbjct: 620 PPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPT 679 Query: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-- 834 +C + V+ + C +P C D D +GC ++YL Q Sbjct: 680 AACHLCLCWEGSVSCEPKAC----APALCPFPARGDCCPD--CDGCEYLGESYLSNQEFP 733 Query: 835 DLCVPRNQCSCHFQGVDY------PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQV 888 D P N C+C V PPG S P + HC C R +G+ Sbjct: 734 DPREPCNLCTCLGGFVTCGRRPCEPPGCSH-PLIPSGHCCPTCQGC--RYHGVTTASGET 790 Query: 889 FVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA--CFLPEECP 946 + D L TC++ + CP L H CF P Sbjct: 791 LPDPLDPTCSL-----CTCQEGSMRCQKKP---------CPPALCPHPSPGPCFCPVCHS 836 Query: 947 CTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPC 981 C +G+E+ G++ P C C CQ G C C Sbjct: 837 CLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQC 874 Score = 39.3 bits (90), Expect = 0.058 Identities = 62/242 (25%), Positives = 85/242 (35%), Gaps = 60/242 (24%) Query: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVA 2345 ++S Q R P C CS C R + F P CE+ I + + P + Sbjct: 934 ISSCAQPRQGPHDCCP-QCSDCEH--EGRKYEPGESFQPGADPCEVCICEPQPEGPPSLR 990 Query: 2346 LTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTY-------QACVTACEPPKTCQDGILG- 2397 CH+ CP L + C T E C +G+LG Sbjct: 991 -------CHRRQ----------CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGS 1033 Query: 2398 ---PLDPEH---CQVLGEGCV---CSEGTI-LHRRHS--ALCIPEAKCACTDSMGVPR-- 2443 P DP + CQ L C+ C E + L RH+ C P + + R Sbjct: 1034 ELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREV 1093 Query: 2444 ALGETWN-------SSLSGCCQHQCQ-------APDTIVPVDLG--CPS--PRPESCLRF 2485 A GE W S ++G + Q Q PD + G CP PRP SC+ F Sbjct: 1094 ASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAF 1153 Query: 2486 GE 2487 G+ Sbjct: 1154 GD 1155 Score = 37.7 bits (86), Expect = 0.17 Identities = 56/248 (22%), Positives = 74/248 (29%), Gaps = 81/248 (32%) Query: 740 ACRCGQPCL-CATLAHYAHL--CRRHGLPV-DFRARLPACALSCEASKEYSPCVAPCGRT 795 AC C C AH H C ++G + P +C C P + Sbjct: 116 ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGP---S 172 Query: 796 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 855 C +L E+C G EC C ++ + + P + C Sbjct: 173 CSELNCLESCTPPG-------ECCPICCTEGGSHWEHGQEWTTPGDPCRI---------- 215 Query: 856 DSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS 915 C C +G + C R A+ CP Sbjct: 216 ---------CRCLEGHIQCRQRECASLCP------------------------------- 235 Query: 916 VSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS--PCHTCVCQRGS 973 AR L G CP D CFL G+E+ G+ V S PC C C GS Sbjct: 236 YPARP--LPGTCCPV-----CDGCFL--------NGREHRSGEPVGSGDPCSHCRCANGS 280 Query: 974 FQCTLHPC 981 QC PC Sbjct: 281 VQCEPLPC 288 Score = 36.6 bits (83), Expect = 0.37 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 8/74 (10%) Query: 924 SGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPC 981 + C C G G LP C+ G+ Y G + SP C TC C G+ QC C Sbjct: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-ETFSPDACTTCRCLTGAVQCQGPSC 173 Query: 982 A-----STCTAYGD 990 + +CT G+ Sbjct: 174 SELNCLESCTPPGE 187 Score = 36.6 bits (83), Expect = 0.37 Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 5/97 (5%) Query: 422 KAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTL 481 K F E A+CH C + ++C P F G P CE+ G Sbjct: 667 KEFASGERFPSPTAACH-LCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGES 725 Query: 482 YPPGSVV---KEDCNTCTCTSGKWECSTAVC-PAECS 514 Y +E CN CTC G C C P CS Sbjct: 726 YLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCS 762 Score = 36.2 bits (82), Expect = 0.49 Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 44/202 (21%) Query: 329 LPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC----HAYVSPLPFTAS----CTSDLCQS 380 LP PP ++PG + G QC P D C H Y S F C CQ+ Sbjct: 286 LPCPPVPCRHPGKIPG---QC----CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA 338 Query: 381 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR 440 G+V+ C CA P G RQ C+ + E + P P Sbjct: 339 -GEVS--CEEQECPVTPCAL---PASG-----RQLCPACELDGEEFAEGVQWEPDG-RPC 386 Query: 441 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-----CP----CEFHGTLYPPGSVVKE- 490 +CV C DG ++ C P + CP C +H +Y G + Sbjct: 387 TACV-----CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDA 441 Query: 491 --DCNTCTCTSGKWECSTAVCP 510 C+ C C G CS CP Sbjct: 442 DSPCHACHCQDGTVTCSLVDCP 463 Score = 35.4 bits (80), Expect = 0.83 Identities = 88/382 (23%), Positives = 121/382 (31%), Gaps = 111/382 (29%) Query: 2381 CVTACEPPKTC------------QDGILGPLDPEHCQVLGEGCVCSEGTILHRRH--SAL 2426 C+ +C PP C + G + C++ C C EG I R+ ++L Sbjct: 178 CLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRI----CRCLEGHIQCRQRECASL 233 Query: 2427 C------IPEAKCACTDSM---GVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSP 2477 C +P C D G GE S C H A ++ L CP Sbjct: 234 CPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG--DPCSHCRCANGSVQCEPLPCP-- 289 Query: 2478 RPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSY 2537 P C G++ CC VC+ +G + RL QE C Sbjct: 290 -PVPCRHPGKIP------GQCCP----VCDGCEYQGHQYQSQETFRL----QERGLCVRC 334 Query: 2538 SCECDPDLCEAE---------------LVPSCRQD--------QILITGRLGDSC----- 2569 SC+ CE + L P+C D Q GR +C Sbjct: 335 SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG 394 Query: 2570 ---CTSYFCACGDC--PDSIPE--CQEGEALTVH-------RNTTELCCPLYQCVCEN-- 2613 C + C C P P C ++ T H +N T+ P + C C++ Sbjct: 395 VPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT 454 Query: 2614 FRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLD-EEFMH---- 2668 C V C T P +CCP C P C L E+ +D E F H Sbjct: 455 VTCSLVDCPPTTCARPQSGPGQCCP----RC-------PDCILEEEVFVDGESFSHPRDP 503 Query: 2669 -----SVENVCGCAKYECVKAP 2685 E C C +AP Sbjct: 504 CQECRCQEGHAHCQPRPCPRAP 525 Score = 33.5 bits (75), Expect = 3.2 Identities = 42/181 (23%), Positives = 61/181 (33%), Gaps = 46/181 (25%) Query: 372 SCTSDLCQSMGDVATWC--RALAEYARACAQAGRPLQGWRT-QLRQCT--------VHCK 420 +CT+ +CQ D A C +A + R C+Q G+ T CT V C+ Sbjct: 113 ACTACVCQ---DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQ 169 Query: 421 EKAFTYNECIA-------CCPASCHPRAS-------------------CVDSEIACVD-- 452 + + C+ CCP C S C++ I C Sbjct: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229 Query: 453 -GCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVK--EDCNTCTCTSGKWECSTAVC 509 CP G C P C +G + G V + C+ C C +G +C C Sbjct: 230 CASLCPYPARPLPGTC-CPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 288 Query: 510 P 510 P Sbjct: 289 P 289 Score = 33.1 bits (74), Expect = 4.1 Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 19/76 (25%) Query: 454 CYCPNGLIF------EDGGCVAPAE-----CP----CEFHGTLYPPGSVVKED----CNT 494 C C G + E GC P CP C +HG G + + C+ Sbjct: 742 CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSL 801 Query: 495 CTCTSGKWECSTAVCP 510 CTC G C CP Sbjct: 802 CTCQEGSMRCQKKPCP 817 Score = 33.1 bits (74), Expect = 4.1 Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 12/84 (14%) Query: 1412 YDACASPCFQTCRDPR------AASCRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDCVE 1465 +D C PC +TC + AA C R CVP C P L E C+ E C + Sbjct: 1426 FDECGPPCPRTCFNQHIPLGELAAHCV-----RPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480 Query: 1466 PAVWVPTEALGNETLPPSQGLPTP 1489 + + LG P + TP Sbjct: 1481 -VLLTGDQPLGARPSPSREPQETP 1503 Score = 32.7 bits (73), Expect = 5.4 Identities = 40/152 (26%), Positives = 53/152 (34%), Gaps = 20/152 (13%) Query: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432 CT+ +CQ D C A+ C +P CT H + A N A Sbjct: 386 CTACVCQ---DGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDAD 442 Query: 433 CPA-SCHPRASCVDSEIAC--VDGCYCPNGLIF--EDGGCVAPAECP-CEFHGTLYPPG- 485 P +CH C D + C VD CP + G CP C ++ G Sbjct: 443 SPCHACH----CQDGTVTCSLVD---CPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGE 495 Query: 486 --SVVKEDCNTCTCTSGKWECSTAVCP-AECS 514 S ++ C C C G C CP A C+ Sbjct: 496 SFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527 Score = 32.7 bits (73), Expect = 5.4 Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 17/90 (18%) Query: 428 ECIA--CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG 485 +C+A C P C P + E C C P GC P PPG Sbjct: 573 QCLARRCVPLPC-PEPVLLPGE--CCPQCPAP-------AGCPRPGAAHARHQEYFSPPG 622 Query: 486 SVVKEDCNTCTCTSGKWECSTAVC-PAECS 514 + C C C G C C PA C+ Sbjct: 623 ----DPCRRCLCLDGSVSCQRLPCPPAPCA 648 Score = 32.0 bits (71), Expect = 9.2 Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 17/92 (18%) Query: 434 PASCHPRASCVDSEIACVDGCYCP----NGLIFEDGGCVAPAECP----CEFHGTLYPPG 485 PA C +++CV CP + E G C CP C HG +P G Sbjct: 853 PAGSCEWCRCQAGQVSCVR-LQCPPLPCKLQVTERGSC-----CPRCRGCLAHGEEHPEG 906 Query: 486 SV-VKED--CNTCTCTSGKWECSTAVCPAECS 514 S V D C++C C G C+ C + C+ Sbjct: 907 SRWVPPDSACSSCVCHEGVVTCARIQCISSCA 938 >gi|239757284 PREDICTED: similar to Fc fragment of IgG binding protein [Homo sapiens] Length = 593 Score = 147 bits (371), Expect = 2e-34 Identities = 143/565 (25%), Positives = 215/565 (38%), Gaps = 79/565 (13%) Query: 618 VRTNVGVRVLYDREGLRLYLQVDQ--RWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 675 + T+ G+RV YD L Y++V + + GLCG +NG+ +DDF P G Sbjct: 23 IETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANE 79 Query: 676 FGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM--FAPC 723 FGNSW+ + SP + +P P C L+ + C +L+ + C Sbjct: 80 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139 Query: 724 SAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 781 + P + C D C G LC+ + Y C+ G V+ C + C Sbjct: 140 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199 Query: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841 + Y C C C L++P C +D C EGC C + QA CVP Sbjct: 200 NSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA--CVPIQ 248 Query: 842 QCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCSDLHTD 898 QC C+ GV Y P + + C C G V+ C +C GQV + Sbjct: 249 QCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEH----SCKPGQVCQPSGGI--- 301 Query: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD--ACFLPEECPCTWKGKEYFP 956 +C ++ S++ G + G A +L +G LP P G Sbjct: 302 ------LSCVTKVTLRSLAQTGVDVEGAA----ILYNGQPLKVLLPLLSPDPCHG----- 346 Query: 957 GDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL----- 1011 P TC Q G C L +TC +GD HY +FDG FDF G C L Sbjct: 347 --VTCRPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 403 Query: 1012 --VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPSP 1060 V + F+V +N N + + + +++ +G ++ + D+ G P Sbjct: 404 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 463 Query: 1061 ESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLK 1120 S D + V + F + + +D V V + G + GLCGN D Sbjct: 464 VSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 520 Query: 1121 TINEMRTPENLELTNPQEFGSSWAA 1145 N+ P + +G SW A Sbjct: 521 PNNDQVFPNGTLAPSIPIWGGSWRA 545 Score = 129 bits (323), Expect = 6e-29 Identities = 84/285 (29%), Positives = 128/285 (44%), Gaps = 20/285 (7%) Query: 232 VQLPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNA 289 ++LP V+ G R Q V++ +A+D V + + GLCGN N Sbjct: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60 Query: 290 DPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPP----CLQQN--PGTMQ 343 DPKDD +G + EF +SW+E P+ P P T P PP C+ + P ++ Sbjct: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT---PCPPGSEDCIPSHKCPPELE 117 Query: 344 GVYEQ---CEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARAC 398 Y++ C L P P +CH V P C DLC G+++ C + Y AC Sbjct: 118 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 177 Query: 399 AQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPN 458 AG ++ WRT+ C + C + Y C C C ++ + C +GC C + Sbjct: 178 QAAGGHVEPWRTE-TFCPMECPPNSH-YELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 235 Query: 459 GLIFEDGGCVAPAECPCEFHGTLY-PPGSVVKEDC-NTCTCTSGK 501 G ++ CV +C C +G Y P +V+ ++C CTC +GK Sbjct: 236 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280 Score = 67.0 bits (162), Expect = 3e-10 Identities = 88/345 (25%), Positives = 125/345 (36%), Gaps = 74/345 (21%) Query: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP---DSCA 2300 GLCG +GD +D +GS G A + F +SW+ VP S + T P D Sbjct: 53 GLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDS-PCLPPTPCPPGSEDCIP 108 Query: 2301 TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQPCV 2344 + C P L ++S+ T S+CH+ V P+ + I D + C Sbjct: 109 SHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCS 168 Query: 2345 ALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDGIL 2396 + YV+ C +E WR +CP C +S Y+ C C P CQDG Sbjct: 169 NIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG-- 226 Query: 2397 GPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2456 EGC C G + + C+P +C C + GV E + L Sbjct: 227 ----------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLIDN 269 Query: 2457 CQHQ--CQAPDTIVPVDLGC-------PSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2507 C+ Q C A +V + C PS SC+ + L T + Sbjct: 270 CRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNG 329 Query: 2508 QTL-----------CEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541 Q L C G+ TCRP + C P+Y C Sbjct: 330 QPLKVLLPLLSPDPCHGV--TCRPQETCKEQGGQGVCLPNYEATC 372 Score = 66.6 bits (161), Expect = 3e-10 Identities = 47/162 (29%), Positives = 70/162 (43%), Gaps = 20/162 (12%) Query: 1098 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV----------E 1147 V V + Q+ GLCGN++ ++ + P + N EFG+SW V Sbjct: 39 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 98 Query: 1148 CP---DTLDPRDMCVLNPLREPFAKKE-CSILLSEV--FEICHPVVDVTWFYSNCLTDTC 1201 CP + P C L + + K+E C +L S CH +VD +C+ D Sbjct: 99 CPPGSEDCIPSHKCP-PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL- 156 Query: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLCPYDC 1242 C GG+ C+++ AY C G V+ WRT CP +C Sbjct: 157 -CLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197 Score = 46.6 bits (109), Expect = 4e-04 Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 13/188 (6%) Query: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199 P ++ C WG H +FDG + G +Y L P + F++ N + G Sbjct: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 424 Query: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254 + + R V++ +G IH + +V G+ LP + R+ Q A ++ Sbjct: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484 Query: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314 +++D V + + G GLCGN + +P +D V +G L + + SW Sbjct: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW- 543 Query: 315 EQAPNQPP 322 +AP P Sbjct: 544 -RAPGWDP 550 >gi|37693519 BMP-binding endothelial regulator precursor protein [Homo sapiens] Length = 685 Score = 145 bits (367), Expect = 4e-34 Identities = 95/332 (28%), Positives = 142/332 (42%), Gaps = 10/332 (3%) Query: 146 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 205 E+ +C +G H TFDG + G Y L F + V ND + S ++ Sbjct: 359 EKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSW 417 Query: 206 SRAVSLFFVGEQEIHLAKEVT--HGGMRVQLPHVMGSARLQQLAGYVI-VRHQSAFTLAW 262 +++V L +GE + L + +T G R+ LP + L GY++ V ++ ++W Sbjct: 418 TKSVELV-LGESRVSLQQHLTVRWNGSRIALPCRAPHFHID-LDGYLLKVTTKAGLEISW 475 Query: 263 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPP 322 DG S V + +P L G GLCGN N +DDL+ G DV +F SW+ ++ Sbjct: 476 DGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN 535 Query: 323 GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMG 382 P P P Q + +C+ L F CH+ V F SC +D+C+ Sbjct: 536 RPQRK--PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPV 593 Query: 383 DVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRAS 442 +C + Y RAC + G + W Q CK A Y+ C C +C Sbjct: 594 HKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA-VYDTCGPGCIKTCDNWNE 651 Query: 443 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 474 CV GC+CP L+ G C+ P CP Sbjct: 652 IGPCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683 Score = 134 bits (338), Expect = 1e-30 Identities = 112/453 (24%), Positives = 174/453 (38%), Gaps = 64/453 (14%) Query: 417 VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC-------VA 469 V+ +F Y+ C AC +C DS + C C P G GC V Sbjct: 244 VYDNGSSFLYDNCTAC---------TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294 Query: 470 PAECP-CEFHGTLYPPGSVVKE-DCNTCTCTSGKWECSTAVC------------------ 509 P + C+F ++ G + +C C C G+ EC C Sbjct: 295 PEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354 Query: 510 ------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 561 P C+V GD H+ TFDGR + F TCQY+L K SS F V ++N + Sbjct: 355 PICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTR 413 Query: 562 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 621 + +SV ++L + +V+L Q V ++ +I P F I L L+V T Sbjct: 414 SFSWTKSVELVLGES---RVSLQQHLTV-RWNGSRIALPCRAPHFHI-DLDGYLLKVTTK 468 Query: 622 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 681 G+ + +D + + + GLCG +NG+ +DD + G + F SW+ Sbjct: 469 AGLEISWDGDSF-VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR 527 Query: 682 TLS--ACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 739 S C+ + C ++ + + C L F C + + ++ C D Sbjct: 528 VESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTD 587 Query: 740 ACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQ 797 C C + C C + Y C+R G+ V + + A C+ Y C C +TC Sbjct: 588 MCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCD 647 Query: 798 DLASPEACGVDGGDDLSRDECVEGCACPPDTYL 830 + C CV GC CP + L Sbjct: 648 NWNEIGPC---------NKPCVAGCHCPANLVL 671 Score = 122 bits (305), Expect = 7e-27 Identities = 138/578 (23%), Positives = 205/578 (35%), Gaps = 104/578 (17%) Query: 746 PCLCATLAHYAHLCRRHGLPVDFR------ARLPACALSCE----------ASKEYSPCV 789 PC+ + C+R PV R + AC C+ +S ++ Sbjct: 66 PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125 Query: 790 APCG-RTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848 PC R CQ+ E+ GV CV C P + +C P C F+ Sbjct: 126 EPCVLRQCQEGVVTES-GV---------RCVVHCKNPLE-----HLGMCCPTCP-GCVFE 169 Query: 849 GVDYPPGDSDIPS---LGHCHCKDGVMSCDSRA-PAAACPA-------GQVFVNC----- 892 GV Y G+ P C C G C P +CP GQ C Sbjct: 170 GVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRK 229 Query: 893 ------------SDLHTDLELSRERTCEQ-QLLNLSVSARGPCLSGCACPQGLLRHGDAC 939 SD++ + C + +V + C C QG + C Sbjct: 230 VFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEEC 289 Query: 940 FL---PEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPCA------------ 982 L PE+ G + F ++ S C C C +G +C C Sbjct: 290 LLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILN 349 Query: 983 ------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS--FSVIVENVN 1028 CT +GD HY TFDG F+F G C+ L K S + F V+V+N Sbjct: 350 RKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDA 409 Query: 1029 CYSSGMICRKFISINVGNSLIVFDDD---SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085 + K + + +G S + N S + H G+ V + Sbjct: 410 RRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVT-TK 468 Query: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145 + + WD + V V A P +G+L GLCGN++ +++ + + +F SW Sbjct: 469 AGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV 528 Query: 1146 VE---C--PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200 C P ++C + A +EC L S F+ CH VD FY +C+TD Sbjct: 529 ESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDM 588 Query: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLC 1238 C C + C+C S AY C + G+ V W + C Sbjct: 589 CECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNC 624 Score = 66.6 bits (161), Expect = 3e-10 Identities = 92/406 (22%), Positives = 154/406 (37%), Gaps = 71/406 (17%) Query: 2058 DCVRHICLEGQLIRVNQS----QHCPQGAAPPRCGILGLAVRVGGDRCCPLW-ECACRCS 2112 +C C++G+ N+ CPQG R G CCP+ E C+ Sbjct: 318 NCTICACVKGRTECRNKQCIPISSCPQGKILNRKG------------CCPICTEKPGVCT 365 Query: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQ---SPDEMLTVHVLDCKSANLGHLNWPPFCLVM 2169 +F D + TFDG Y+L++ SP V V + + +W ++ Sbjct: 366 VFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTRSFSWTKSVELV 424 Query: 2170 LNMTHLAHQ--VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLH 2227 L + ++ Q +T+ ++ + P F I+ G++ + T + ++I W Sbjct: 425 LGESRVSLQQHLTVRWNGSRIAL-------PCRAPHFHIDLDGYLLKVTTKAGLEISW-D 476 Query: 2228 SSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSS-L 2286 + V A+ K + GLCG +G +DL DG+ +D F +SW+V S+ Sbjct: 477 GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD---FAESWRVESNEF 533 Query: 2287 TSVGQTRFRPDSCATT---------DCSPCLRMVSNRTFSACHRFVPPESF--------C 2329 + Q + P+ C T +C + + + F CH V +F C Sbjct: 534 CNRPQRKPVPELCQGTVKVKLRAHREC----QKLKSWEFQTCHSTVDYATFYRSCVTDMC 589 Query: 2330 ELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL-CSSDSTYQACVTACEPP 2388 E + Y C + Y C + + + W C C + Y C C Sbjct: 590 ECPVHKNCY----CESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGC--I 643 Query: 2389 KTCQD-GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433 KTC + +GP + + C GC C +LH+ CI C Sbjct: 644 KTCDNWNEIGPCN-KPCVA---GCHCPANLVLHK---GRCIKPVLC 682 Score = 41.6 bits (96), Expect = 0.012 Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 12/154 (7%) Query: 364 VSPLPFTASCTSDLCQSMGDVATWCRALAEY-ARACAQAGRPLQGWRTQLRQCTV--HCK 420 V +PF +C + T R +R CA A + Q + CT + Sbjct: 56 VLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTY 115 Query: 421 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP-CEFHG 479 +F + C +S + CV C P E G P CP C F G Sbjct: 116 NSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNP----LEHLGMCCPT-CPGCVFEG 170 Query: 480 TLYPPGSVVKED---CNTCTCTSGKWECSTAVCP 510 Y G + + C C+CT G+ +C VCP Sbjct: 171 VQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCP 204 Score = 34.7 bits (78), Expect = 1.4 Identities = 12/26 (46%), Positives = 15/26 (57%) Query: 921 PCLSGCACPQGLLRHGDACFLPEECP 946 PC++GC CP L+ H C P CP Sbjct: 658 PCVAGCHCPANLVLHKGRCIKPVLCP 683 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.134 0.439 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 137,194,974 Number of Sequences: 37866 Number of extensions: 7656353 Number of successful extensions: 50730 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 141 Number of HSP's successfully gapped in prelim test: 1713 Number of HSP's that attempted gapping in prelim test: 28679 Number of HSP's gapped (non-prelim): 12000 length of query: 2924 length of database: 18,247,518 effective HSP length: 120 effective length of query: 2804 effective length of database: 13,703,598 effective search space: 38424888792 effective search space used: 38424888792 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.