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Search of human proteins with 116235478
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116235478 establishment of cohesion 1 homolog 1 [Homo
sapiens]
(840 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116235478 establishment of cohesion 1 homolog 1 [Homo sapiens] 1668 0.0
gi|62899035 establishment of cohesion 1 homolog 2 [Homo sapiens] 311 2e-84
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 68 4e-11
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 63 1e-09
gi|104526627 triadin [Homo sapiens] 61 5e-09
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 59 2e-08
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 58 3e-08
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 57 9e-08
gi|109637791 transcription factor-like nuclear regulator [Homo s... 56 1e-07
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 55 3e-07
gi|47578107 delangin isoform B [Homo sapiens] 54 6e-07
gi|47578105 delangin isoform A [Homo sapiens] 54 6e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 54 8e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 54 8e-07
gi|87299628 biorientation of chromosomes in cell division 1-like... 53 1e-06
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 53 1e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 52 2e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 52 2e-06
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 52 3e-06
gi|31982906 cingulin-like 1 [Homo sapiens] 52 3e-06
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 51 4e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 51 4e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 51 4e-06
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 51 4e-06
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 51 4e-06
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 51 4e-06
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 51 5e-06
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 51 5e-06
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 51 5e-06
gi|38569484 kinesin family member 21A [Homo sapiens] 50 9e-06
>gi|116235478 establishment of cohesion 1 homolog 1 [Homo sapiens]
Length = 840
Score = 1668 bits (4319), Expect = 0.0
Identities = 840/840 (100%), Positives = 840/840 (100%)
Query: 1 MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP 60
MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP
Sbjct: 1 MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP 60
Query: 61 ELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR 120
ELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR
Sbjct: 61 ELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR 120
Query: 121 RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL 180
RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL
Sbjct: 121 RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL 180
Query: 181 EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV 240
EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV
Sbjct: 181 EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV 240
Query: 241 PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKR 300
PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKR
Sbjct: 241 PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKR 300
Query: 301 GSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDV 360
GSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDV
Sbjct: 301 GSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDV 360
Query: 361 QCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRT 420
QCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRT
Sbjct: 361 QCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRT 420
Query: 421 SFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAP 480
SFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAP
Sbjct: 421 SFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAP 480
Query: 481 ENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKI 540
ENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKI
Sbjct: 481 ENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKI 540
Query: 541 DTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKT 600
DTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKT
Sbjct: 541 DTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKT 600
Query: 601 DEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILA 660
DEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILA
Sbjct: 601 DEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILA 660
Query: 661 EYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVG 720
EYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVG
Sbjct: 661 EYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVG 720
Query: 721 CLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRR 780
CLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRR
Sbjct: 721 CLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRR 780
Query: 781 KKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST 840
KKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST
Sbjct: 781 KKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST 840
>gi|62899035 establishment of cohesion 1 homolog 2 [Homo sapiens]
Length = 601
Score = 311 bits (796), Expect = 2e-84
Identities = 167/383 (43%), Positives = 237/383 (61%), Gaps = 18/383 (4%)
Query: 454 KMKEINSEEVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFS 513
+ ++ SE ++ +D+ K T A P L+ ++K SAS+KN
Sbjct: 232 RTQKSKSEVIEDSDVETVSEKKT--------FATRQVPKCLVLEEKLKIGLLSASSKNKE 283
Query: 514 QCLESKLEN---SPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRE 570
+ ++ ++ S V S+ + GENK + I S +S +S
Sbjct: 284 KLIKDSSDDRVSSKEHKVDKNEAFSSEDSL--GENKTISPKSTVYPIFS-ASSVNSKRSL 340
Query: 571 TPRNHSLPKCNSHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASN 630
S+ N + I K+ ++ K + QLIIDAGQK FGA C CGM+YTASN
Sbjct: 341 GEEQFSVGSVNFMKQTNIQKNTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASN 400
Query: 631 PEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVD 690
PEDE QH+ H++F+ +KYVGWKKER++AE+ DG+I++VLP DP +A+KKV++++E+VD
Sbjct: 401 PEDEMQHVQHHHRFLEGIKYVGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVD 460
Query: 691 NDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRF 750
N+LGFQQ C ++ KT LFIS++K+VVGCLIAE I+ +RV+ E + E
Sbjct: 461 NELGFQQVVPKCPNKIKTFLFISDEKRVVGCLIAEPIKQAFRVLSEPI----GPESPSST 516
Query: 751 ERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSD 810
E +AW CS +PEPA+CGISRIWVF + RRK+IA R+++ LR+ F++G +LS +EIAFSD
Sbjct: 517 ECPRAWQCSDVPEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSD 576
Query: 811 PTPDGKLFATQYCGTGQFLVYNF 833
PTPDGKLFAT+YC T FLVYNF
Sbjct: 577 PTPDGKLFATKYCNTPNFLVYNF 599
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 67.8 bits (164), Expect = 4e-11
Identities = 81/378 (21%), Positives = 154/378 (40%), Gaps = 25/378 (6%)
Query: 8 SKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGP-KETIKSQAKSSSESKINQPELETRM 66
+KE + + + +++ +++ K+ A+ P KE KS A+ S K P E
Sbjct: 588 AKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAK 647
Query: 67 STRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQ 126
S +K+ ++A KS K V+ ++ K K K KA + ++ +
Sbjct: 648 SPEKAKSPEKEEA-KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE 706
Query: 127 QLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDS 186
+ + +S E + + +++ P K + ++KS + ++ K K L+VKS
Sbjct: 707 KAKSPVKEEAKSPE-KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPE 765
Query: 187 KEDENLVINEVINSP------KGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV 240
+ E SP K K E + + + K P+K + E
Sbjct: 766 AKTP---AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKS 822
Query: 241 PVTSEVKRSKMATSVVPKKNEMKKSVHT------QVNTNTTLPK--SPQPSVPEQSDNEL 292
PV E K ++ PKK E +K+ T + + PK +P+P V E+ + +
Sbjct: 823 PVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAV 882
Query: 293 EQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILH 352
E+ +SK ++ +E A + + K+ +++E ++ KP E K E E
Sbjct: 883 EKPKESK----VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE-KTEVAKKEPDDAK 937
Query: 353 QKETNQDVQCNRFFPSRK 370
KE ++ + P +K
Sbjct: 938 AKEPSKPAEKKEAAPEKK 955
Score = 63.2 bits (152), Expect = 1e-09
Identities = 73/366 (19%), Positives = 147/366 (40%), Gaps = 35/366 (9%)
Query: 5 QEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELET 64
+E+ KE ++++ ET+ +++ + + K +K +AKS +E+K PE E
Sbjct: 480 EEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAK--SPEKEE 537
Query: 65 RMSTRSSKAASNDKA-TKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRS- 122
S K+ K+ K K+ + +E K K A E+ +
Sbjct: 538 AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE 597
Query: 123 ------------QRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKS-NK 169
+ + E + +V++ +++ PTK+E S ++KS K
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 657
Query: 170 TSQKHVKRKVLEVKSDSKEDENL--VINEVINSPKGKKRKVEHQTACACSSQCTQGSEKC 227
K ++ VK+++K E + SP+ K V+ + ++ + ++
Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEE------AKSPEKAKSP 711
Query: 228 PQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQ 287
++ + E PV E K + A S V ++ + + + T KSP+ P +
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAK 771
Query: 288 SD-----NELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVK-----EEKPT 337
+ ++ + KS ++ E+ ++ D +KE + E VK EEKP
Sbjct: 772 EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ 831
Query: 338 EIKLEE 343
E+K++E
Sbjct: 832 EVKVKE 837
Score = 58.2 bits (139), Expect = 3e-08
Identities = 77/377 (20%), Positives = 148/377 (39%), Gaps = 57/377 (15%)
Query: 9 KENSSKVTKKSDDKNSETEIQDSQKNLAKKSGP---KETIKSQAKSSSESKINQPELETR 65
KE + + + +++ ++ K+ A+ P K +K +AKS +E+K P E
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAK--SPVKEEA 626
Query: 66 MSTRSSKAASNDKA-TKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQR 124
S K+ K+ TK K+ + +E K K V K+ E+
Sbjct: 627 KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK------- 679
Query: 125 LQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSN-KTSQKHVKRKVLEVK 183
++ + ++ +++ P K+E S ++KS K K ++ VK
Sbjct: 680 ------------AKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727
Query: 184 SDSKEDENL--VINEVINSPKGKKRKVEHQTACACSSQC-TQGSEKCPQKTTRRDETKPV 240
++K E + E SP+ K + +T S + T E+ + E
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS 787
Query: 241 PVTSEVKRSKMATS-----------VVPKKNEMKKSVHTQVNTNTTLPKSP--------- 280
PV EVK + A S +PKK E+K V + K P
Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847
Query: 281 --QPSVPEQSDNELEQAGKSK--RGSILQLCEEIAGEIESDNVEVKKESSQ----MESVK 332
P E+ D++ E+A K + + + + E + + VE KKE ++ + + +
Sbjct: 848 PATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907
Query: 333 EEKPTEIKLEETSVERQ 349
+E P +++++E + ++
Sbjct: 908 KEAPAKVEVKEDAKPKE 924
Score = 38.1 bits (87), Expect = 0.034
Identities = 49/251 (19%), Positives = 106/251 (42%), Gaps = 21/251 (8%)
Query: 6 EKSKENSSKVTKKSDDKNS--ETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELE 63
EK+K + K + S + + + +K + KK K +K + K E K+ +P +
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ-EVKVKEPPKK 841
Query: 64 TRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKL-VHENPKANEQLNRRS 122
KA + K + K++ +E+ K K+ +KK E PK ++ ++
Sbjct: 842 AE----EEKAPATPKTEEK--KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKK- 894
Query: 123 QRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQ---SKSNKTSQKHVKRKV 179
++ + + +E +V+ VK+ P +K + + + +K+ + S+ K++
Sbjct: 895 ---EEAEDKKKVPTPEKEAPAKVE-VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEA 950
Query: 180 LEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKP 239
K D+KE++ E PK + + E + + + +T + ++KP
Sbjct: 951 APEKKDTKEEKAKKPEE---KPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKP 1007
Query: 240 VPVTSEVKRSK 250
+E K +K
Sbjct: 1008 PEKATEDKAAK 1018
Score = 32.7 bits (73), Expect = 1.4
Identities = 18/74 (24%), Positives = 40/74 (54%), Gaps = 2/74 (2%)
Query: 5 QEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELET 64
+E + + +K ++ K + E +D+++ AKK P+E K++AK+ + K E
Sbjct: 931 KEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKK--PEEKPKTEAKAKEDDKTLSKEPSK 988
Query: 65 RMSTRSSKAASNDK 78
+ ++ K++S D+
Sbjct: 989 PKAEKAEKSSSTDQ 1002
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 62.8 bits (151), Expect = 1e-09
Identities = 73/359 (20%), Positives = 157/359 (43%), Gaps = 25/359 (6%)
Query: 14 KVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKA 73
K TK +S ++ + K L KS KE S+ ++ +K+N E ++ ++
Sbjct: 531 KQTKLKQRADSRESLKPAAKPLPSKSVRKE---SKEETPEVTKVNHVEKPPKVESKEKVM 587
Query: 74 ASNDKATKSINKNTVTVRGYSQES----TKKKLSQKKLVHENPK-ANEQLNRRSQRLQQL 128
DK K+ K +VT + + K ++++K+ PK A E+ ++ +++
Sbjct: 588 VKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPE 647
Query: 129 TEVSRRSLRSREI--QGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKV------L 180
+ + +E+ + +K+ P K+E + + K +K K++V
Sbjct: 648 DKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPK 707
Query: 181 EVKSDSKEDENLVINEVINSPKGKKRKV--EHQTACACSSQCTQGSEKCPQKTTRRDETK 238
EVK + K++E + + PK + +K+ + + + S+ + + P+ + + K
Sbjct: 708 EVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVK 767
Query: 239 PVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTN-TTLPKSPQPSVPEQSDNELEQAGK 297
V + + K V+ K+ + ++V V T TT + + +A +
Sbjct: 768 KDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAER 827
Query: 298 SKRGSILQLCEEIAGEIESDNVEVKKE-SSQMESVKEEKPTEIKLEETSVERQILHQKE 355
S S L ++ E++++ V+V K+ Q+E +++E+ KL+ET + QKE
Sbjct: 828 SLMSSPEDLTKDFE-ELKAEEVDVTKDIKPQLELIEDEE----KLKETEPVEAYVIQKE 881
Score = 48.1 bits (113), Expect = 3e-05
Identities = 58/241 (24%), Positives = 107/241 (44%), Gaps = 26/241 (10%)
Query: 123 QRLQQLTEVSRRSLRSREIQGQVQA--VKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL 180
++L+ L + + +++ GQV VKQ TK +Q + ++ +S K + K + K +
Sbjct: 503 EKLKHLDFLKQPLATQKDLTGQVPTPVVKQ----TKLKQRADSR-ESLKPAAKPLPSKSV 557
Query: 181 EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETK-- 238
+S + E +N V PK VE + +E P T + +K
Sbjct: 558 RKESKEETPEVTKVNHVEKPPK-----VESKEKVMVKKDKPIKTETKPSVTEKEVPSKEE 612
Query: 239 PVPVTSEVKRSKMATSVVPK---KNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNE-LEQ 294
P PV +EV K AT V PK + +KK + + P+ V ++ D +++
Sbjct: 613 PSPVKAEVAE-KQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKK 671
Query: 295 AGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQK 354
K K+ EE+ E++ + + +K+ + E KE P E+K E E++ + ++
Sbjct: 672 EEKPKK-------EEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKE 724
Query: 355 E 355
E
Sbjct: 725 E 725
Score = 33.9 bits (76), Expect = 0.65
Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 51/350 (14%)
Query: 5 QEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELET 64
+EK+ + +KV K +DK E E +K +AKK K IK + K E E
Sbjct: 634 KEKTVKKETKV--KPEDKKEEKE--KPKKEVAKKE-DKTPIKKEEKPKKE--------EV 680
Query: 65 RMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQR 124
+ + K K K + +E K++ + K + PK +
Sbjct: 681 KKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPK---------KE 731
Query: 125 LQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKS 184
+++L + +++S + A+K +P KKE+ S + S + K K+ +K
Sbjct: 732 IKKLPKDAKKSSTPLSEAKKPAALKPKVP--KKEE--SVKKDSVAAGKPKEKGKIKVIKK 787
Query: 185 DSKEDENL------------VINEVINSPKGKKRKVEHQTACACSSQ-CTQGSEKCPQKT 231
+ K E + V+ + G +++E + + S + T+ E+ K
Sbjct: 788 EGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEEL--KA 845
Query: 232 TRRDETKPVPVTSEV--------KRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPS 283
D TK + E+ + + V+ K+ E+ K + T +
Sbjct: 846 EEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGEC 905
Query: 284 VPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKE 333
EQ+ ELE K I + +E AG ES +E ++ E +E
Sbjct: 906 --EQTPEELEPVEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEEAEE 953
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 60.8 bits (146), Expect = 5e-09
Identities = 117/564 (20%), Positives = 225/564 (39%), Gaps = 86/564 (15%)
Query: 7 KSKENSSKVTKKSD--DKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPEL-E 63
+ KE T+K + ++ +T++ +K K+ +E K + K++ + KI + E E
Sbjct: 139 RKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEK-VREKEKPEKKATHKEKIEKKEKPE 197
Query: 64 TRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENP-KANEQLNRRS 122
T+ + K A A KS K V+G QE K+ ++ K V + P K E+ ++
Sbjct: 198 TKTLAKEQKKAKT--AEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEK 255
Query: 123 QRLQQLTEVSRRSLRSREIQ---------GQVQAVKQSLPPTKKEQCSSTQSKSNKTSQK 173
+ + + + + I GQ A+ PP EQ S S +K
Sbjct: 256 AAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIP---PPLPTEQASRPTPASPALEEK 312
Query: 174 HVKRKVLEVK--SDSKEDENLVINEVINSPKGKKRKVEHQTACAC-------SSQCTQGS 224
++K E K S++K+ E I K+K E +TA +S+ QG+
Sbjct: 313 EGEKKKAEKKVTSETKKKEKEDI----------KKKSEKETAIDVEKKEPGKASETKQGT 362
Query: 225 EK-----CPQKTTRRDETKPVPVTSEV------KRSKMATSVVPKKNEMK-------KSV 266
K +K +++++K +EV K+ K V P K+ K K V
Sbjct: 363 VKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQV 422
Query: 267 HTQ----------VNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGE--- 313
+ V+ +P + + + E+ + K SIL+ E I G+
Sbjct: 423 KAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEK 482
Query: 314 ----IESDNVEVKKESSQMESVKEEKPTEIKLE---ETSVERQILHQKE--TNQDVQCNR 364
++ E KK+ ++ KE KP +L+ E E QI + + ++ VQ ++
Sbjct: 483 VPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHK 542
Query: 365 FFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSP 424
KP K + +G K + + K + K + ++T
Sbjct: 543 ---QDIVKPEKTVSHG-KPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPK 598
Query: 425 PALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAPENCH 484
P + VT+S T++ ++ + ++ MK + E+V +++++ T +A +
Sbjct: 599 PTPKGTSEVTESGKKKTEISEKE-SKEKADMKHLREEKVSTRKESLQLHNVT-KAEKPAR 656
Query: 485 LANEIKPSDPPLDNQMKHSFDSAS 508
++ +++ D P + K + S
Sbjct: 657 VSKDVE--DVPASKKAKEGTEDVS 678
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 58.9 bits (141), Expect = 2e-08
Identities = 94/433 (21%), Positives = 169/433 (39%), Gaps = 79/433 (18%)
Query: 17 KKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQ----------------- 59
KK++ K E + +D +K +K KE +++ K S+ K +Q
Sbjct: 231 KKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTG 290
Query: 60 --PELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQK-----------K 106
P E + T ++ N+ K +K +E KKK K K
Sbjct: 291 VIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAK 350
Query: 107 LVHENPKANEQLNRRSQRLQQLTEVSRRS---LRSREIQGQVQAVKQSLPPTKKEQCSST 163
L E + + R +RL++L E R+ L + + + Q K+ KKE T
Sbjct: 351 LKEEEERQKREEEERIKRLEEL-EAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLT 409
Query: 164 QSKSNKTSQKHVKRKVLEVKS-DSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQ 222
+S+ ++ K+L+ + + ++L I K K++K+ Q S + ++
Sbjct: 410 KSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDK-KRKKIPQQLE---SKEVSE 465
Query: 223 GSEKCP------QKTTRRDETKPVPVTSEVKRSK----------MATSVVPKKNEMKKSV 266
E C Q ++ET P PV E + MA+ +K E K V
Sbjct: 466 SMELCAAVEVMEQGVPEKEETPP-PVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNK-V 523
Query: 267 HTQVNTNTTLPKSPQPSVPE--QSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKE 324
H +V N + + E +S+ E E+ G+S+ + E+++ E +S KK
Sbjct: 524 HIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKP 583
Query: 325 SSQMES----------VKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPV 374
S +M S KEE+ + K + +R++ H K N + + P+
Sbjct: 584 SKEMSSDSEYDSDDDRTKEERAYD-KAKRRIEKRRLEHSKNVNTE---------KLRAPI 633
Query: 375 KCILNGINSSAKK 387
C+L +++ K
Sbjct: 634 ICVLGHVDTGKTK 646
Score = 49.7 bits (117), Expect = 1e-05
Identities = 75/381 (19%), Positives = 159/381 (41%), Gaps = 46/381 (12%)
Query: 1 MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQ- 59
+ S + + K +K + N + + K +A+K K+ + + + ++K+ +
Sbjct: 194 LQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKL 253
Query: 60 ---PELETRMSTRSSKAASNDKATKSINKNTVTV-RGYSQESTKKKLSQKKLVHENPKAN 115
ELET +S + S K + K+ VTV G S +K + +N
Sbjct: 254 KEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDK 313
Query: 116 EQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHV 175
++ +++ ++ ++ E + + + V+A++++L K+E + + + ++ +
Sbjct: 314 KKKDKKKKKGEK--EEKEKEKKKGPSKATVKAMQEALAKLKEE-----EERQKREEEERI 366
Query: 176 KRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEH-----------QTACACSSQCT--- 221
KR + E+++ KE+E L + + +K + E Q ++ T
Sbjct: 367 KR-LEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKL 425
Query: 222 ---QGSEKCPQKTTRRDETKPVPVTSEVKRSK----MATSVVPKKNEMKKSVHTQVNTNT 274
QG E P K + K P+ + KR K + + V + E+ +V
Sbjct: 426 LQAQGVE-VPSKDSL---PKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVP 481
Query: 275 TLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEE 334
++P P PE+ + + E AG L E +A + E++ VE K +++ EE
Sbjct: 482 EKEETPPPVEPEE-EEDTEDAG-------LDDWEAMASDEETEKVEGNKVHIEVKENPEE 533
Query: 335 KPTEIKLEETSVERQILHQKE 355
+ E + EE E + ++E
Sbjct: 534 EEEEEEEEEEDEESEEEEEEE 554
Score = 39.7 bits (91), Expect = 0.012
Identities = 55/304 (18%), Positives = 124/304 (40%), Gaps = 38/304 (12%)
Query: 46 KSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQK 105
K++++ S++ I+ L + + + +K K + + ++ K+L +
Sbjct: 6 KNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEEL 65
Query: 106 KLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQS 165
L + KA+ + E + + + + +G+ KQS E+ S
Sbjct: 66 SLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGK----KQSFDDNDSEELEDKDS 121
Query: 166 KSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSE 225
KS KT++ V E+ S S +D++ N++ KGK +K S++ GSE
Sbjct: 122 KSKKTAKPKV-----EMYSGSDDDDD--FNKLPKKAKGKAQK---------SNKKWDGSE 165
Query: 226 KCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVP 285
+ DE + ++K S +E + + ++ P P++
Sbjct: 166 E--------DEDN----SKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNI- 212
Query: 286 EQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETS 345
+S NE + A I + ++ A + E + + +E +++ +KE++ E ++ S
Sbjct: 213 -ESGNEDDDAS----FKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQS 267
Query: 346 VERQ 349
+++
Sbjct: 268 KQKE 271
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 58.2 bits (139), Expect = 3e-08
Identities = 95/387 (24%), Positives = 151/387 (39%), Gaps = 84/387 (21%)
Query: 170 TSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQ 229
+ ++ K+K + K D KE + PK KK E +T K P+
Sbjct: 637 SQEEKKKKKRSKAKKDPKEPKE---------PKEKKEPKEPKTP------------KAPK 675
Query: 230 KTTRRDETKPVPVTSEVKRSKMATSVVP--KKNEMKKSVH---TQVNTNTTLPKSPQPSV 284
E K T + K SK +++ P + + +KK V+ T+ + N+ L K+P PS
Sbjct: 676 IPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSP 735
Query: 285 PEQSDNELEQAGKSKRGSILQ-------------LCEEIAGEIES---DNVEVKKESSQM 328
P + D E G KR S Q + +E A + ++ D+ +S Q
Sbjct: 736 PPEED---EDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQ 792
Query: 329 ESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKT-KPVKCILNGINSSAKK 387
ESV E P +E+ R + QKE+ ++V+ F+ K + C I K
Sbjct: 793 ESVDAEGPV---VEKIMSSRSVKKQKESGEEVEIEEFYVKYKNFSYLHCQWASIEDLEKD 849
Query: 388 NSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMH-------------HPVT 434
KIK K Q NK S++ +L F+P +E+ PVT
Sbjct: 850 KRIQQKIKRFKAKQGQ-NKFLSEIEDEL------FNPDYVEVDRIMDFARSTDDRGEPVT 902
Query: 435 QSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAPENCHLANEIKPSDP 494
L + T E+ ++I+ +++ E K R PE + P
Sbjct: 903 HYLVKWCSLPYEDST--WERRQDIDQAKIE------EFEKLMSREPETERVER------P 948
Query: 495 PLDNQMKHSFDSASNKNFSQCLESKLE 521
P D+ K S S KN ++ E +LE
Sbjct: 949 PADD-WKKSESSREYKNNNKLREYQLE 974
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 56.6 bits (135), Expect = 9e-08
Identities = 79/380 (20%), Positives = 155/380 (40%), Gaps = 53/380 (13%)
Query: 6 EKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETR 65
E SKE+S + ++ D++ E E ++ +++ ++ +E + + SS ++ +P+
Sbjct: 1063 ELSKESSEEEEEEEDEEEEEEE-EEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ---- 1117
Query: 66 MSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRL 125
S A + K R + T + +S+ V P N R +L
Sbjct: 1118 -----SVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQL 1172
Query: 126 QQLTEVSRRSLRSREIQGQVQAVKQSLP--PTKKEQCSSTQSKSNKT------SQKHVKR 177
+ E+ E G+ ++++ P KK Q + K N + ++
Sbjct: 1173 EPTCEIEV------EEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMND 1226
Query: 178 KVLEVKSDSKED-ENLVINEVINSPKGKKRKV-------EHQTACACSSQCTQGSEKCP- 228
+K SK++ E L +V PKG KR + E +T + + P
Sbjct: 1227 DSSNLKEGSKDNPEPLKCKQVW--PKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPD 1284
Query: 229 -------QKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQ 281
QK T +T P P+ E + + +++P++ ++ V+ NT+ + P+
Sbjct: 1285 EQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPE 1344
Query: 282 PSV--PEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEI 339
+ PE+ + E E+ + + EE GE E V+K+ +S ++E+P EI
Sbjct: 1345 DDLIKPEEEEEEEEEEEEEE--------EEEEGEEEEGGGNVEKDPDGAKSQEKEEP-EI 1395
Query: 340 KLEETSVERQILHQKETNQD 359
E+ R H++E +D
Sbjct: 1396 STEKEDSARLDDHEEEEEED 1415
Score = 32.0 bits (71), Expect = 2.5
Identities = 26/122 (21%), Positives = 54/122 (44%), Gaps = 3/122 (2%)
Query: 254 SVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEE--IA 311
+V ++ E +K + + K Q + ++++ A + L E +
Sbjct: 996 AVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVT 1055
Query: 312 GEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKT 371
GE +E+ KESS+ E +E++ E + EE + + ++E ++ + + P R T
Sbjct: 1056 GE-RGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLT 1114
Query: 372 KP 373
KP
Sbjct: 1115 KP 1116
>gi|109637791 transcription factor-like nuclear regulator [Homo
sapiens]
Length = 2624
Score = 56.2 bits (134), Expect = 1e-07
Identities = 138/629 (21%), Positives = 245/629 (38%), Gaps = 76/629 (12%)
Query: 28 IQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNT 87
+Q + N K + KE + SQ + + + N+ E + R + D++ K +
Sbjct: 708 LQKPKPNAGKAAERKEILISQEEIGANVEKNENE---SCADRDTPQHMEDQSRKDFEEED 764
Query: 88 VTVRGYSQESTK-------KKLSQKKLVHENPKANE--QLNRRSQRLQQLTEVSRRSLRS 138
V ++ +S + K L++ V EN KAN+ Q+ R Q+ R
Sbjct: 765 VILQPEKNDSFQNVQPDEPKVLNECLSVQENNKANKLNQVPILRTRFQKPKPNIGRGTGR 824
Query: 139 REIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKV--LEVKSDSKEDENLVINE 196
REI + + +++ L + + + + ++ V ++ E++SD KE I
Sbjct: 825 REISSKEEVLEKILVSGEMAAALRETVRLDTSPKEMVPAEINTKEMQSDLKETGRRAI-- 882
Query: 197 VINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRR--DETKPVPVT------SEVKR 248
SP+ K V T + G E C ++ T D T+ + E+
Sbjct: 883 ---SPREKILDVIDDTIEMETGLKAMGREICLREKTPEVIDATEEIDKDLEEAGRREISP 939
Query: 249 SKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPS-VPEQSDNELEQAGKSKRGSILQLC 307
K V E++ + N ++ K+P+ + E+ D LE+ G+ K
Sbjct: 940 QKNGPEEVKPLGEVETDLKATGNESSPREKTPEVTDATEEIDKNLEETGRRKISPRENGP 999
Query: 308 EEI--AGEIESDNVEVKKESSQMESVKE--EKPTEIKLEETSVERQI------------L 351
EE+ E+E+D +ESS E E + EI LEET ER++ L
Sbjct: 1000 EEVKPVDEMETDLNATGRESSPREKTPEVIDATEEIDLEET--EREVSPQENGLEEVKPL 1057
Query: 352 HQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQV 411
+ ET+ FP KT V + I ++ + S Q N L+ +V
Sbjct: 1058 GEMETDLKATGRDSFPRGKTPEVIDAIEEIEIDLEET--------EREISPQENGLE-EV 1108
Query: 412 SPKLGLLRTSFSPPALEMH-HPVTQSTFLGTKLHDRNI--TCQQEKMKEINS-EEVKIND 467
P LG ++T E+ T T+ D+++ T ++E E N EEVK D
Sbjct: 1109 KP-LGEMQTDLKATGREISPREKTPEVIDATEEIDKDLEETGRREISPEENGPEEVKPVD 1167
Query: 468 ITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSAS------------NKNFSQC 515
KTT R + E+ + ++ ++ + S K +
Sbjct: 1168 EMETDLKTTGREGSSREKTREVIDAAEVIETDLEETEREISPQENGPEEVKPVGKMETDL 1227
Query: 516 LESKLENSPVENVTAASTLLSQAKID---TGENKFPGSAPQQHSILSNQTSKSSDNRETP 572
E + E S E V A + + + +ID TG+ P + ++ +D +ET
Sbjct: 1228 KEIREEISQREKVLAEFSAIREKEIDLKETGKRDIP-IMEKVSGKMAVVEEMEADLKETG 1286
Query: 573 RNHSLPKCNSHLEITIPKDLKLKEAEKTD 601
+ + + + + +T K +LK+ KTD
Sbjct: 1287 KENFRERGSEEICVTEEKVAELKQTGKTD 1315
Score = 30.4 bits (67), Expect = 7.1
Identities = 56/261 (21%), Positives = 101/261 (38%), Gaps = 46/261 (17%)
Query: 102 LSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCS 161
L QK L E + + + S + ++ T+ R++++ +++ + V + + S
Sbjct: 370 LLQKVLAEEEKRKQKSVKNHSLKEKKSTK-PRKNVKVKKVA--CEGVNNDPDESMSSRIS 426
Query: 162 STQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRK-------------V 208
T+ SQK + E + S+ED V EV + K ++RK +
Sbjct: 427 DTER-----SQKDAQTVEEESLTLSREDAEQVALEVDLNQKKRRRKKQDGANELGVNNLL 481
Query: 209 EHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRS----------KMATSVVPK 258
E+ T A S+ + KC R E K + E S +T V K
Sbjct: 482 ENATVQAGPSKGEKHKNKC---QAIRPELKEGECSKEQMLSCTQNIDGIVGFASTEKVEK 538
Query: 259 KNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGE---IE 315
+ + S+ Q + + +S + S + E+ I LCE E IE
Sbjct: 539 RTDPILSLSNQQDATSVATESSESSTSDLPSFEV---------GIRALCEVNNAEGSCIE 589
Query: 316 SDNVEVKKESSQMESVKEEKP 336
NV++K S +++ + KP
Sbjct: 590 ERNVDLKNNSLEIDQTENVKP 610
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 55.1 bits (131), Expect = 3e-07
Identities = 47/190 (24%), Positives = 77/190 (40%), Gaps = 4/190 (2%)
Query: 1 MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSE---SKI 57
+ +EK EN K +KS +K S+K KK K++ +S + SSS S
Sbjct: 58 LAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSS 117
Query: 58 NQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQ 117
+ E E + + K N ++ KS +T S+ES KKK K +
Sbjct: 118 SDSEDEEKKQGKRRKKKKN-RSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSL 176
Query: 118 LNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKR 177
+R + +S S + + VQA K+ +++ + K K +KH K+
Sbjct: 177 SKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKK 236
Query: 178 KVLEVKSDSK 187
K + S K
Sbjct: 237 KKKKSGSSHK 246
Score = 31.6 bits (70), Expect = 3.2
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 5/175 (2%)
Query: 96 ESTKKKL--SQKKLVHENP---KANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQ 150
E+ KK+L S++KL+ N K E+ +R ++ + + S S S K+
Sbjct: 67 ENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKK 126
Query: 151 SLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEH 210
KK++ S +S + T + + K K +DE +V + K +K+
Sbjct: 127 QGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPD 186
Query: 211 QTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKS 265
+ S E+ Q +R + +VK+ K K + KKS
Sbjct: 187 DKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKS 241
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 53.9 bits (128), Expect = 6e-07
Identities = 116/530 (21%), Positives = 215/530 (40%), Gaps = 58/530 (10%)
Query: 3 SIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPEL 62
S++ + + KKSD + S++E++ S+ LA+ S P E + KSS + +L
Sbjct: 588 SLKSTPENHPETPKKKSDPELSKSEMKQSESRLAE-SKPNENRLVETKSS------ENKL 640
Query: 63 ETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRS 122
ET++ T++ + N+ T +N T+ + K ++ +L P N+Q N RS
Sbjct: 641 ETKVETQTEELKQNESRTTECKQNESTI-------VEPKQNENRLSDTKPNDNKQNNGRS 693
Query: 123 QRLQQLTEVSRRSLRSR------EIQGQVQAVKQ---SLPPTKKEQCSSTQSKSNKTSQK 173
+ + E ++ SR + G + KQ P T K++ +S+ QK
Sbjct: 694 ETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQK---GESRPETPKQK 750
Query: 174 HVKR-KVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTT 232
+ R + + + D++ D E KK +V S SE+ +
Sbjct: 751 NEGRPETPKHRHDNRRDSGKPSTE-------KKPEVSKHKQDTKSDSPRLKSERA-EALK 802
Query: 233 RRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSD--- 289
+R + + V + S ++E + ++V TL S + +SD
Sbjct: 803 QRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHGIKSDSSK 862
Query: 290 -NELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVER 348
++LE+ + + G + +GE +S + +S +++ K KL S
Sbjct: 863 TDKLERKHRHESGDSRE--RPSSGEQKS-----RPDSPRVKQGDSNKSRSDKLGFKSPTS 915
Query: 349 QILHQKETNQD-VQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSV--QHN 405
+ + E N+ V N+ P K + +L G S A KN KIK K +V +
Sbjct: 916 KDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGG-RSGALKNFVIPKIKRDKDGNVTQETK 974
Query: 406 KLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEK----MKEINSE 461
K++ + PK + + + PV L + I +++K +K I ++
Sbjct: 975 KMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNK 1034
Query: 462 EVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKN 511
K N +++ + E PE L EI+ S PL ++K + S N
Sbjct: 1035 PSKSNKGSIDQSVLKELPPE---LLAEIE-STMPLCERVKMNKRKRSTVN 1080
Score = 35.0 bits (79), Expect = 0.29
Identities = 37/182 (20%), Positives = 78/182 (42%), Gaps = 27/182 (14%)
Query: 4 IQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQ---- 59
+++K KE S +K+++ +SE E+ +K+ ++ + S + S SE IN
Sbjct: 2473 VKDKRKERKSSPSKENESSDSEEEVSRPRKS-------RKRVDSDSDSDSEDDINSVMKC 2525
Query: 60 -PELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQ---------ESTK---KKLSQKK 106
PE + + + + ++ + G+S ES K K +++K
Sbjct: 2526 LPENSAPL-IEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKT 2584
Query: 107 LVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSK 166
VH +PK R ++TE +RS+ + + + + + L P ++E+ +
Sbjct: 2585 GVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYL--DFKLLMEHLDPDEEEEEGEVSAS 2642
Query: 167 SN 168
+N
Sbjct: 2643 TN 2644
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 53.9 bits (128), Expect = 6e-07
Identities = 116/530 (21%), Positives = 215/530 (40%), Gaps = 58/530 (10%)
Query: 3 SIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPEL 62
S++ + + KKSD + S++E++ S+ LA+ S P E + KSS + +L
Sbjct: 588 SLKSTPENHPETPKKKSDPELSKSEMKQSESRLAE-SKPNENRLVETKSS------ENKL 640
Query: 63 ETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRS 122
ET++ T++ + N+ T +N T+ + K ++ +L P N+Q N RS
Sbjct: 641 ETKVETQTEELKQNESRTTECKQNESTI-------VEPKQNENRLSDTKPNDNKQNNGRS 693
Query: 123 QRLQQLTEVSRRSLRSR------EIQGQVQAVKQ---SLPPTKKEQCSSTQSKSNKTSQK 173
+ + E ++ SR + G + KQ P T K++ +S+ QK
Sbjct: 694 ETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQK---GESRPETPKQK 750
Query: 174 HVKR-KVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTT 232
+ R + + + D++ D E KK +V S SE+ +
Sbjct: 751 NEGRPETPKHRHDNRRDSGKPSTE-------KKPEVSKHKQDTKSDSPRLKSERA-EALK 802
Query: 233 RRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSD--- 289
+R + + V + S ++E + ++V TL S + +SD
Sbjct: 803 QRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHGIKSDSSK 862
Query: 290 -NELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVER 348
++LE+ + + G + +GE +S + +S +++ K KL S
Sbjct: 863 TDKLERKHRHESGDSRE--RPSSGEQKS-----RPDSPRVKQGDSNKSRSDKLGFKSPTS 915
Query: 349 QILHQKETNQD-VQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSV--QHN 405
+ + E N+ V N+ P K + +L G S A KN KIK K +V +
Sbjct: 916 KDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGG-RSGALKNFVIPKIKRDKDGNVTQETK 974
Query: 406 KLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEK----MKEINSE 461
K++ + PK + + + PV L + I +++K +K I ++
Sbjct: 975 KMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNK 1034
Query: 462 EVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKN 511
K N +++ + E PE L EI+ S PL ++K + S N
Sbjct: 1035 PSKSNKGSIDQSVLKELPPE---LLAEIE-STMPLCERVKMNKRKRSTVN 1080
Score = 35.0 bits (79), Expect = 0.29
Identities = 37/182 (20%), Positives = 78/182 (42%), Gaps = 27/182 (14%)
Query: 4 IQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQ---- 59
+++K KE S +K+++ +SE E+ +K+ ++ + S + S SE IN
Sbjct: 2473 VKDKRKERKSSPSKENESSDSEEEVSRPRKS-------RKRVDSDSDSDSEDDINSVMKC 2525
Query: 60 -PELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQ---------ESTK---KKLSQKK 106
PE + + + + ++ + G+S ES K K +++K
Sbjct: 2526 LPENSAPL-IEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKT 2584
Query: 107 LVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSK 166
VH +PK R ++TE +RS+ + + + + + L P ++E+ +
Sbjct: 2585 GVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYL--DFKLLMEHLDPDEEEEEGEVSAS 2642
Query: 167 SN 168
+N
Sbjct: 2643 TN 2644
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 53.5 bits (127), Expect = 8e-07
Identities = 122/591 (20%), Positives = 225/591 (38%), Gaps = 74/591 (12%)
Query: 9 KENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMST 68
K + K K + S T D K + K + ++ SES ELE + +
Sbjct: 730 KTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKS 789
Query: 69 RSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQL 128
S A+ + TK NT E KK H+N K +++ + +Q
Sbjct: 790 MSKIGAA--RTTKKRIPNTKDFDSSEDEKHSKK-GMDNQGHKNLKTSQEGSSDDAERKQE 846
Query: 129 TEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVK------RKVLEV 182
E + + + + ++ LP KK+Q S++ +K S K RKV E
Sbjct: 847 RETFSSAEGTVDKDTTIMELRDRLP--KKQQASASTDGVDKLSGKEQSFTSLEVRKVAET 904
Query: 183 KSDSKEDENLVINEVIN-----SPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDET 237
K SK + +V + + K K+ +T+ Q +G+E+ +K +
Sbjct: 905 KEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEE--KKKPSDFKK 962
Query: 238 KPVPVTSEVKRSKMATSVVPKKNEM---KKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQ 294
K + + + + S T +P++ E+ K + Q+ TT E+ ++
Sbjct: 963 KVIKMEQQYESSSDGTEKLPEREEICHFPKGI-KQIKNGTT--------DGEKKSKKIRD 1013
Query: 295 AGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQK 354
K+ + E+ G+ +S + K+S +E+K ++ L ++S +RQ
Sbjct: 1014 KTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKL-LGKSSRKRQDCSSS 1072
Query: 355 ETN----QDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQ 410
+T ++ CN ++ K ++ + N S+K+N+ K + S + +S
Sbjct: 1073 DTEKYSMKEDGCNS--SDKRLKRIE-LRERRNLSSKRNT-----KEIQSGSSSSDAEESS 1124
Query: 411 VSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITC---------QQEKMKEINSE 461
K RTS A+ + S TK +IT Q + E +S+
Sbjct: 1125 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1184
Query: 462 EVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLE 521
E KI +T EN L++ + S D A +K+ ++ +
Sbjct: 1185 EQKIKPVT-----------ENLVLSSH--------TGFCQSSGDEALSKSVPVTVDDDDD 1225
Query: 522 NSPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETP 572
++ EN A LL + K + ++ GS+ + +T K N E P
Sbjct: 1226 DNDPENRIAKKMLLEEIKANLSSDE-DGSSDDEPEEGKKRTGK--QNEENP 1273
Score = 46.6 bits (109), Expect = 1e-04
Identities = 74/402 (18%), Positives = 156/402 (38%), Gaps = 61/402 (15%)
Query: 7 KSKENSSKVTKKSDDKN-SETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETR 65
K K+ S +K D +N S++ I + + N KS ET+ + S I +
Sbjct: 648 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAI------LK 701
Query: 66 MSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRL 125
+R S ++S+D I+ N T+ ++ K ++K ++ +
Sbjct: 702 EVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAK 761
Query: 126 QQLTEVSRRSLRSR------EIQGQVQAV-KQSLPPTKKEQCSSTQSKSNKTSQKHVKRK 178
+ +R +S E++ +++++ K T K++ +T+ + +KH K+
Sbjct: 762 SSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKG 821
Query: 179 VLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGS------EKCPQKTT 232
+ D++ +NL ++ S +RK E +T + + + ++ P+K
Sbjct: 822 M-----DNQGHKNLKTSQE-GSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQ 875
Query: 233 RRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNEL 292
T V S ++S + V +KS H + T
Sbjct: 876 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKT-------------------- 915
Query: 293 EQAGKSKRGSILQLCEEIAGEIESDNV-EVKKESSQMESVKEEKPTEIKLEETSVERQIL 351
K + + + E+ + +SD E K+ S+ + +++KP++ K + +E+Q
Sbjct: 916 ---CKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYE 972
Query: 352 HQKETNQDVQCNRFFPSRK-----TKPVKCILNGINSSAKKN 388
+ + + P R+ K +K I NG KK+
Sbjct: 973 SSSDGTEKL------PEREEICHFPKGIKQIKNGTTDGEKKS 1008
Score = 45.4 bits (106), Expect = 2e-04
Identities = 76/389 (19%), Positives = 160/389 (41%), Gaps = 64/389 (16%)
Query: 8 SKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETI--KSQAKSSSESKINQPELETR 65
SK N+ ++ S ++E +D++K + S K+ + K + ++S + + + +
Sbjct: 1104 SKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADIT 1163
Query: 66 MSTRSS----------KAASNDKATKSINKNTV--TVRGYSQESTKKKLSQKK--LVHEN 111
S+ S + +S+++ K + +N V + G+ Q S + LS+ V ++
Sbjct: 1164 SSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDD 1223
Query: 112 PKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTS 171
N+ NR ++++ L E + +L S E ++ T K Q++ N
Sbjct: 1224 DDDNDPENRIAKKM--LLEEIKANLSSDEDGSSDDEPEEGKKRTGK------QNEENPGD 1275
Query: 172 QKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKT 231
++ + E SDS+E + P+ + R + H+ + E +K
Sbjct: 1276 EEAKNQVNSESDSDSEESKK---------PRYRHRLLRHKLTVS-------DGESGEEKK 1319
Query: 232 TRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTT--LPKSPQPSVPEQSD 289
T+ E K V + R K+++ + + V +V+ + P++ E +
Sbjct: 1320 TKPKEHKEVKGRN---RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEE 1376
Query: 290 NELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQ 349
N+ K KR I +++ D+ SS+ +S EE+ E + EE E +
Sbjct: 1377 NQRSYKQKKKRRRI---------KVQEDS------SSENKSNSEEEEEEKEEEEEEEEEE 1421
Query: 350 ILHQKETNQDVQCNRFFPSRKTKPVKCIL 378
+++ N D + P + K ++ IL
Sbjct: 1422 EEEEEDENDDSKS----PGKGRKKIRKIL 1446
Score = 43.9 bits (102), Expect = 6e-04
Identities = 69/351 (19%), Positives = 150/351 (42%), Gaps = 42/351 (11%)
Query: 2 MSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSG--PKETIKSQAKSSSESK--- 56
+S + +KE S + +++SE + Q+ +KK KE ++ ++S++ K
Sbjct: 1102 LSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQAD 1161
Query: 57 ---INQPELETRMSTRSSKAASNDKATKSINKNTV--TVRGYSQESTKKKLSQK--KLVH 109
+ ++E + +S+++ K + +N V + G+ Q S + LS+ V
Sbjct: 1162 ITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVD 1221
Query: 110 ENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNK 169
++ N+ NR ++++ L E + +L S E P + ++ + Q++ N
Sbjct: 1222 DDDDDNDPENRIAKKM--LLEEIKANLSSDEDGSSDD------EPEEGKKRTGKQNEENP 1273
Query: 170 TSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQ 229
++ + E SDS+E + P+ + R + H+ E +
Sbjct: 1274 GDEEAKNQVNSESDSDSEESK---------KPRYRHRLLRHKLT-------VSDGESGEE 1317
Query: 230 KTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQV--NTNTTLPKSPQPSVPEQ 287
K T+ E K V + R K+++ + + V +V + + P++ E
Sbjct: 1318 KKTKPKEHKEVKGRN---RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1374
Query: 288 SDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTE 338
+N+ K KR I ++ E+ + E +S++ E ++E + E +EE+ E
Sbjct: 1375 EENQRSYKQKKKRRRI-KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEE 1424
Score = 43.9 bits (102), Expect = 6e-04
Identities = 64/302 (21%), Positives = 131/302 (43%), Gaps = 37/302 (12%)
Query: 2 MSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSES---KIN 58
M ++E SS SDD+ E + + ++N +++ E K+Q S S+S +
Sbjct: 1237 MLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQN--EENPGDEEAKNQVNSESDSDSEESK 1294
Query: 59 QPELETRMS----TRSSKAASNDKATKSINKNTVTVRG---YSQESTKKKLSQKKLVHEN 111
+P R+ T S + +K TK V R S E ++ Q+ V E
Sbjct: 1295 KPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEE 1354
Query: 112 PKANEQLNR---RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSN 168
+E R RS + +L E ++RS + ++ + ++ K ++ SS+++KSN
Sbjct: 1355 VSESEDEQRPRTRSAKKAELEE-NQRSYKQKKKRRRI----------KVQEDSSSENKSN 1403
Query: 169 KTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKR--------KVEHQTACACSSQC 220
++ K + E + + +E+E ++ + KG+K+ K+ +T A +
Sbjct: 1404 SEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE- 1462
Query: 221 TQGSEKCPQKTTRRDETKPVPVTSEVKRSK--MATSVVPKKNEMKKSVHTQVNTNTTLPK 278
+ ++ ++ R++ + V + +K + T +V ++E K QV+ N +
Sbjct: 1463 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL 1522
Query: 279 SP 280
P
Sbjct: 1523 KP 1524
Score = 41.2 bits (95), Expect = 0.004
Identities = 87/405 (21%), Positives = 150/405 (37%), Gaps = 85/405 (20%)
Query: 4 IQEKSKENSSKVTKKSD-DKNSETEIQDSQKNLAKKSGP----KETIK--SQAKSSSESK 56
+Q+ + + K KK D+ SE + + S+K +K P K+ IK Q +SSS+
Sbjct: 919 VQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGT 978
Query: 57 INQPELET------RMSTRSSKAASNDKATKSINKNTVTVRG----YSQESTKKKLSQKK 106
PE E + + +K +K I T + Y+++ST K S
Sbjct: 979 EKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDS 1038
Query: 107 LVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSK 166
+ K N R +R + L + SR+ R+ K S+ K++ C+S
Sbjct: 1039 SEDKKSK-NGAYGREKKRCKLLGKSSRK----RQDCSSSDTEKYSM---KEDGCNS---- 1086
Query: 167 SNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEK 226
S K +KR L +E NL KR + + + SS + SE
Sbjct: 1087 ----SDKRLKRIEL------RERRNL----------SSKRNTKEIQSGSSSSDAEESSED 1126
Query: 227 CPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTN------------- 273
+K R K + E KR+ + TS K+ ++ S + + +
Sbjct: 1127 NKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQ 1186
Query: 274 -------------------TTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEI 314
++ ++ SVP D++ + R + L EEI +
Sbjct: 1187 KIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANL 1246
Query: 315 ESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQD 359
SD + SS E + +K T + EE + + +Q + D
Sbjct: 1247 SSD----EDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESD 1287
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 53.5 bits (127), Expect = 8e-07
Identities = 122/591 (20%), Positives = 225/591 (38%), Gaps = 74/591 (12%)
Query: 9 KENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMST 68
K + K K + S T D K + K + ++ SES ELE + +
Sbjct: 768 KTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKS 827
Query: 69 RSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQL 128
S A+ + TK NT E KK H+N K +++ + +Q
Sbjct: 828 MSKIGAA--RTTKKRIPNTKDFDSSEDEKHSKK-GMDNQGHKNLKTSQEGSSDDAERKQE 884
Query: 129 TEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVK------RKVLEV 182
E + + + + ++ LP KK+Q S++ +K S K RKV E
Sbjct: 885 RETFSSAEGTVDKDTTIMELRDRLP--KKQQASASTDGVDKLSGKEQSFTSLEVRKVAET 942
Query: 183 KSDSKEDENLVINEVIN-----SPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDET 237
K SK + +V + + K K+ +T+ Q +G+E+ +K +
Sbjct: 943 KEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEE--KKKPSDFKK 1000
Query: 238 KPVPVTSEVKRSKMATSVVPKKNEM---KKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQ 294
K + + + + S T +P++ E+ K + Q+ TT E+ ++
Sbjct: 1001 KVIKMEQQYESSSDGTEKLPEREEICHFPKGI-KQIKNGTT--------DGEKKSKKIRD 1051
Query: 295 AGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQK 354
K+ + E+ G+ +S + K+S +E+K ++ L ++S +RQ
Sbjct: 1052 KTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKL-LGKSSRKRQDCSSS 1110
Query: 355 ETN----QDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQ 410
+T ++ CN ++ K ++ + N S+K+N+ K + S + +S
Sbjct: 1111 DTEKYSMKEDGCNS--SDKRLKRIE-LRERRNLSSKRNT-----KEIQSGSSSSDAEESS 1162
Query: 411 VSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITC---------QQEKMKEINSE 461
K RTS A+ + S TK +IT Q + E +S+
Sbjct: 1163 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1222
Query: 462 EVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLE 521
E KI +T EN L++ + S D A +K+ ++ +
Sbjct: 1223 EQKIKPVT-----------ENLVLSSH--------TGFCQSSGDEALSKSVPVTVDDDDD 1263
Query: 522 NSPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETP 572
++ EN A LL + K + ++ GS+ + +T K N E P
Sbjct: 1264 DNDPENRIAKKMLLEEIKANLSSDE-DGSSDDEPEEGKKRTGK--QNEENP 1311
Score = 46.6 bits (109), Expect = 1e-04
Identities = 74/402 (18%), Positives = 156/402 (38%), Gaps = 61/402 (15%)
Query: 7 KSKENSSKVTKKSDDKN-SETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETR 65
K K+ S +K D +N S++ I + + N KS ET+ + S I +
Sbjct: 686 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAI------LK 739
Query: 66 MSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRL 125
+R S ++S+D I+ N T+ ++ K ++K ++ +
Sbjct: 740 EVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAK 799
Query: 126 QQLTEVSRRSLRSR------EIQGQVQAV-KQSLPPTKKEQCSSTQSKSNKTSQKHVKRK 178
+ +R +S E++ +++++ K T K++ +T+ + +KH K+
Sbjct: 800 SSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKG 859
Query: 179 VLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGS------EKCPQKTT 232
+ D++ +NL ++ S +RK E +T + + + ++ P+K
Sbjct: 860 M-----DNQGHKNLKTSQE-GSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQ 913
Query: 233 RRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNEL 292
T V S ++S + V +KS H + T
Sbjct: 914 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKT-------------------- 953
Query: 293 EQAGKSKRGSILQLCEEIAGEIESDNV-EVKKESSQMESVKEEKPTEIKLEETSVERQIL 351
K + + + E+ + +SD E K+ S+ + +++KP++ K + +E+Q
Sbjct: 954 ---CKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYE 1010
Query: 352 HQKETNQDVQCNRFFPSRK-----TKPVKCILNGINSSAKKN 388
+ + + P R+ K +K I NG KK+
Sbjct: 1011 SSSDGTEKL------PEREEICHFPKGIKQIKNGTTDGEKKS 1046
Score = 45.4 bits (106), Expect = 2e-04
Identities = 76/389 (19%), Positives = 160/389 (41%), Gaps = 64/389 (16%)
Query: 8 SKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETI--KSQAKSSSESKINQPELETR 65
SK N+ ++ S ++E +D++K + S K+ + K + ++S + + + +
Sbjct: 1142 SKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADIT 1201
Query: 66 MSTRSS----------KAASNDKATKSINKNTV--TVRGYSQESTKKKLSQKK--LVHEN 111
S+ S + +S+++ K + +N V + G+ Q S + LS+ V ++
Sbjct: 1202 SSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDD 1261
Query: 112 PKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTS 171
N+ NR ++++ L E + +L S E ++ T K Q++ N
Sbjct: 1262 DDDNDPENRIAKKM--LLEEIKANLSSDEDGSSDDEPEEGKKRTGK------QNEENPGD 1313
Query: 172 QKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKT 231
++ + E SDS+E + P+ + R + H+ + E +K
Sbjct: 1314 EEAKNQVNSESDSDSEESKK---------PRYRHRLLRHKLTVS-------DGESGEEKK 1357
Query: 232 TRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTT--LPKSPQPSVPEQSD 289
T+ E K V + R K+++ + + V +V+ + P++ E +
Sbjct: 1358 TKPKEHKEVKGRN---RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEE 1414
Query: 290 NELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQ 349
N+ K KR I +++ D+ SS+ +S EE+ E + EE E +
Sbjct: 1415 NQRSYKQKKKRRRI---------KVQEDS------SSENKSNSEEEEEEKEEEEEEEEEE 1459
Query: 350 ILHQKETNQDVQCNRFFPSRKTKPVKCIL 378
+++ N D + P + K ++ IL
Sbjct: 1460 EEEEEDENDDSKS----PGKGRKKIRKIL 1484
Score = 43.9 bits (102), Expect = 6e-04
Identities = 69/351 (19%), Positives = 150/351 (42%), Gaps = 42/351 (11%)
Query: 2 MSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSG--PKETIKSQAKSSSESK--- 56
+S + +KE S + +++SE + Q+ +KK KE ++ ++S++ K
Sbjct: 1140 LSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQAD 1199
Query: 57 ---INQPELETRMSTRSSKAASNDKATKSINKNTV--TVRGYSQESTKKKLSQK--KLVH 109
+ ++E + +S+++ K + +N V + G+ Q S + LS+ V
Sbjct: 1200 ITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVD 1259
Query: 110 ENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNK 169
++ N+ NR ++++ L E + +L S E P + ++ + Q++ N
Sbjct: 1260 DDDDDNDPENRIAKKM--LLEEIKANLSSDEDGSSDD------EPEEGKKRTGKQNEENP 1311
Query: 170 TSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQ 229
++ + E SDS+E + P+ + R + H+ E +
Sbjct: 1312 GDEEAKNQVNSESDSDSEESK---------KPRYRHRLLRHKLT-------VSDGESGEE 1355
Query: 230 KTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQV--NTNTTLPKSPQPSVPEQ 287
K T+ E K V + R K+++ + + V +V + + P++ E
Sbjct: 1356 KKTKPKEHKEVKGRN---RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1412
Query: 288 SDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTE 338
+N+ K KR I ++ E+ + E +S++ E ++E + E +EE+ E
Sbjct: 1413 EENQRSYKQKKKRRRI-KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEE 1462
Score = 43.9 bits (102), Expect = 6e-04
Identities = 64/302 (21%), Positives = 131/302 (43%), Gaps = 37/302 (12%)
Query: 2 MSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSES---KIN 58
M ++E SS SDD+ E + + ++N +++ E K+Q S S+S +
Sbjct: 1275 MLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQN--EENPGDEEAKNQVNSESDSDSEESK 1332
Query: 59 QPELETRMS----TRSSKAASNDKATKSINKNTVTVRG---YSQESTKKKLSQKKLVHEN 111
+P R+ T S + +K TK V R S E ++ Q+ V E
Sbjct: 1333 KPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEE 1392
Query: 112 PKANEQLNR---RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSN 168
+E R RS + +L E ++RS + ++ + ++ K ++ SS+++KSN
Sbjct: 1393 VSESEDEQRPRTRSAKKAELEE-NQRSYKQKKKRRRI----------KVQEDSSSENKSN 1441
Query: 169 KTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKR--------KVEHQTACACSSQC 220
++ K + E + + +E+E ++ + KG+K+ K+ +T A +
Sbjct: 1442 SEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE- 1500
Query: 221 TQGSEKCPQKTTRRDETKPVPVTSEVKRSK--MATSVVPKKNEMKKSVHTQVNTNTTLPK 278
+ ++ ++ R++ + V + +K + T +V ++E K QV+ N +
Sbjct: 1501 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL 1560
Query: 279 SP 280
P
Sbjct: 1561 KP 1562
Score = 41.2 bits (95), Expect = 0.004
Identities = 87/405 (21%), Positives = 150/405 (37%), Gaps = 85/405 (20%)
Query: 4 IQEKSKENSSKVTKKSD-DKNSETEIQDSQKNLAKKSGP----KETIK--SQAKSSSESK 56
+Q+ + + K KK D+ SE + + S+K +K P K+ IK Q +SSS+
Sbjct: 957 VQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGT 1016
Query: 57 INQPELET------RMSTRSSKAASNDKATKSINKNTVTVRG----YSQESTKKKLSQKK 106
PE E + + +K +K I T + Y+++ST K S
Sbjct: 1017 EKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDS 1076
Query: 107 LVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSK 166
+ K N R +R + L + SR+ R+ K S+ K++ C+S
Sbjct: 1077 SEDKKSK-NGAYGREKKRCKLLGKSSRK----RQDCSSSDTEKYSM---KEDGCNS---- 1124
Query: 167 SNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEK 226
S K +KR L +E NL KR + + + SS + SE
Sbjct: 1125 ----SDKRLKRIEL------RERRNL----------SSKRNTKEIQSGSSSSDAEESSED 1164
Query: 227 CPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTN------------- 273
+K R K + E KR+ + TS K+ ++ S + + +
Sbjct: 1165 NKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQ 1224
Query: 274 -------------------TTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEI 314
++ ++ SVP D++ + R + L EEI +
Sbjct: 1225 KIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANL 1284
Query: 315 ESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQD 359
SD + SS E + +K T + EE + + +Q + D
Sbjct: 1285 SSD----EDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESD 1325
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 52.8 bits (125), Expect = 1e-06
Identities = 123/611 (20%), Positives = 233/611 (38%), Gaps = 120/611 (19%)
Query: 7 KSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRM 66
K+ E +SK ++ T+ + + +++A K KS A S E P+ E
Sbjct: 228 KTSERASKKLPSQPTTDTSTDKERTSEDMADKE------KSTADSGGEGLETAPKSE-EF 280
Query: 67 STRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQ 126
S TK N + + QES+++K + P +NE+ R+ ++ +
Sbjct: 281 SDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKE 340
Query: 127 QLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDS 186
+ + S +S + Q +V+ KQ+ K+++ S + S K S K K +E +
Sbjct: 341 KTEKKFDHSKKSEDTQ-KVKDEKQA----KEKEVESLKLPSEKNSN---KAKTVE---GT 389
Query: 187 KEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEV 246
KED +L+ ++V + T S ++ ++T+ VTS+
Sbjct: 390 KEDFSLIDSDVDG-----------------LTDITVSSVHTSDLSSFEEDTEEEVVTSDS 432
Query: 247 KRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQ--------SDNELEQAGKS 298
TS +KN+ K+ +++ KS + + + SD++ E +
Sbjct: 433 MEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQ 492
Query: 299 KRGSILQLCEE--IAGEIESDNVEVKK----ESSQMESVKEEKPTEIKLEETSVERQILH 352
+R SI + EE + +I + +E K+ E ++ K + + + LEE+S +
Sbjct: 493 RRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSL--- 549
Query: 353 QKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVS 412
K +K +L KK + K K N +++K Q
Sbjct: 550 ---------------EPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQ-- 592
Query: 413 PKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEI 472
+ L T H C++EK+ +S+E+K E
Sbjct: 593 ------------------YEEDSKETLKTSEH-----CEKEKIS--SSKELKHVHAKSEP 627
Query: 473 NKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAAS 532
+K R E+ H+ +E K N+ K + + +E E + +V
Sbjct: 628 SKPARRLSESLHVVDENK-------NESKLEREHKRRTSTPVIMEGVQEETDTRDV---K 677
Query: 533 TLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDL 592
+ +++I T E + +Q S L N+ D+ ETP HL+ + K++
Sbjct: 678 RQVERSEICTEEPQ------KQKSTLKNEKHLKKDDSETP----------HLKSLLKKEV 721
Query: 593 KLKEAEKTDEK 603
K + + EK
Sbjct: 722 KSSKEKPEREK 732
Score = 46.6 bits (109), Expect = 1e-04
Identities = 133/684 (19%), Positives = 255/684 (37%), Gaps = 113/684 (16%)
Query: 6 EKSKENSSKVTKKSDDKNSET--EIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELE 63
E +KE+ S + D T + S + ++ +E + S + E + E
Sbjct: 387 EGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKN 446
Query: 64 TRMSTRSSKAASNDKATKSI-----NKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQL 118
+ T++ + S++ TKS+ +K + + YS + + Q++ K L
Sbjct: 447 KQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLL 506
Query: 119 NRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRK 178
R+ R + E R+ + + + +S ++ S + K+ + + +RK
Sbjct: 507 RRQINR--EKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERK 564
Query: 179 VLEVK-SDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDET 237
VLE K + SK+ + N NS K ++ + + + S C + +K + E
Sbjct: 565 VLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEK------EKISSSKEL 618
Query: 238 KPVPVTSEVKR-----SKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNEL 292
K V SE + S+ V KNE K + T+T P + E E
Sbjct: 619 KHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTST-------PVIMEGVQEET 671
Query: 293 EQAGKSKRGSILQLCEEIAGEIES---DNVEVKKESSQMESVKEEKPTEIKLEETSVERQ 349
+ ++ ++C E + +S + +KK+ S+ +K E+K + ER+
Sbjct: 672 DTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPERE 731
Query: 350 --------------------------ILHQKETNQDVQCNRFFPSRKTKPVKCILNGINS 383
LH E V+ N S++TK L+ +
Sbjct: 732 KTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTK-----LSSDDK 786
Query: 384 SAKKNSNWTKIKLS------KFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQST 437
+ +K+ + + KLS K S K D V + S + H +S+
Sbjct: 787 TERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSS 846
Query: 438 -------FLGTKLH-----------------------DRNITCQQEKMKEINSEEVKIND 467
LG+K H D N+ ++ KE + + +
Sbjct: 847 DSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEE 906
Query: 468 ITVEINKTTERAPENCHLANEI-----KPSDPPLDNQMKHSFDSASNKNFSQCLESK-LE 521
V +K+ + + + E+ K + P ++ K++ ++ S K +E K E
Sbjct: 907 KLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFE 966
Query: 522 NSPVENV--TAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPK 579
+ VE V TA+S+ S K + K P A +++ + TS + + + + S
Sbjct: 967 ETGVEPVLETASSSAHSTQKDSSHRAKLP-LAKEKYKSDKDSTSTRLERKLSDGHKSRSL 1025
Query: 580 CNSHLEITIPKDLKLKEAEKTDEK 603
+S KD+K K+ K+D+K
Sbjct: 1026 KHS------SKDIKKKDENKSDDK 1043
Score = 42.4 bits (98), Expect = 0.002
Identities = 108/593 (18%), Positives = 221/593 (37%), Gaps = 73/593 (12%)
Query: 20 DDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSS-ESKINQPELETRMSTRSSKAASNDK 78
D+ +E++++ K E ++ + + + ++ + E+ T + N+K
Sbjct: 642 DENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEK 701
Query: 79 ATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRS 138
K + T ++ ++ K S++K E + ++L S + + + ++
Sbjct: 702 HLKKDDSETPHLKSLLKKEVKS--SKEKPEREKTPSEDKL---SVKHKYKGDCMHKTGDE 756
Query: 139 REIQGQVQAVK--QSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINE 196
E+ + +K +++ ++ S+ K+ + S+ +RK+ + D K +I
Sbjct: 757 TELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKT 816
Query: 197 VINSPK----------GKKRKVEHQTACACSSQCTQGS-------------------EKC 227
N K +K K EH++ + S+ + S +KC
Sbjct: 817 DENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKC 876
Query: 228 PQKTTRRDET-KPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPE 286
+T D KP V + KR S++ +K +K TQ Q V E
Sbjct: 877 DMDSTNMDSNLKPEEVVHKEKR--RTKSLLEEKLVLKSKSKTQ---------GKQVKVVE 925
Query: 287 QSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSV 346
EL Q G +K+ + + +E N E Q +S E+KP E E +
Sbjct: 926 ---TEL-QEGATKQATTPKPDKE-------KNTEENDSEKQRKSKVEDKPFEETGVEPVL 974
Query: 347 ERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNK 406
E T +D P K K + +K S+ K + K +S K
Sbjct: 975 ETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKK 1034
Query: 407 LDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKIN 466
D S S + + + +R + QE K E++ N
Sbjct: 1035 KDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAK--GEEKLAAN 1092
Query: 467 DITVEINKTTERAPE--NCHLANEIKP----SDPPLDNQMKHSFDSASNKNFSQCLESKL 520
++ + +R + + L E +P S+P ++N + S + N SQ +
Sbjct: 1093 TLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEPGVENVFEVSKTQDNRNNNSQ---QDI 1149
Query: 521 ENSPVENVTAASTLLSQAKIDTGENK--FPGSAPQQHSILSNQTSKSSDNRET 571
++ ++ T+A+ + + T ++K P P + + +++ + K +D+R T
Sbjct: 1150 DSENMKQKTSATVQKDELRTCTADSKATAPAYKPGRGTGVNSNSEKHADHRST 1202
Score = 39.7 bits (91), Expect = 0.012
Identities = 71/363 (19%), Positives = 134/363 (36%), Gaps = 39/363 (10%)
Query: 1 MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP 60
+M+ E + ++ S K S D T+I S K + + S + S E
Sbjct: 1923 IMNANENNVDSMSGTEKGSKD----TDICSSAKGIVESS-----VTSAVSGKDEVTPVPG 1973
Query: 61 ELETRMSTRSSKAASNDKATKSINKNTVT---VRGYSQESTKKKLSQKKLVHENPKANEQ 117
E M++ +S +D + + T++ V G ++ + ++ H +P E
Sbjct: 1974 GCEGPMTSAASD--QSDSQLEKVEDTTISTGLVGGSYDVLVSGEVPECEVAHTSPSEKED 2031
Query: 118 L-------NRRSQRLQQLTE----VSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSK 166
N L T ++ SL + QG+V + S Q S+
Sbjct: 2032 EDIITSVENEECDGLMATTASGDITNQNSLAGGKNQGKVLIISTSTTNDYTPQVSAITDV 2091
Query: 167 SNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEK 226
S ++++ + V E +P + A S+ ++
Sbjct: 2092 EGGLSDA--------LRTEENMEGTRVTTEEFEAPMPSAVSGDDSQLTASRSE---EKDE 2140
Query: 227 CPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPE 286
C +T E +P++S K A S+ P +++ V +T + P PS P
Sbjct: 2141 CAMISTSIGEEFELPISSATT-IKCAESLQPVAAAVEERATGPVLISTADFEGPMPSAPP 2199
Query: 287 QSDNELEQAGKSKRGSILQLCEEIAGEIES--DNVEVKKESSQMESVKEEKPTEIKLEET 344
++++ L K ++ + IA E E+ V V+ E+ + +V EEK + +
Sbjct: 2200 EAESPLASTSKEEKDECALISTSIAEECEASVSGVVVESENERAGTVMEEKDGSGIISTS 2259
Query: 345 SVE 347
SVE
Sbjct: 2260 SVE 2262
Score = 38.9 bits (89), Expect = 0.020
Identities = 68/342 (19%), Positives = 118/342 (34%), Gaps = 61/342 (17%)
Query: 5 QEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELET 64
+ +S ++SSK KK D+ S+ K G KE S K+ S + + +L
Sbjct: 1021 KSRSLKHSSKDIKKKDENKSD-----------DKDG-KEVDSSHEKARGNSSLMEKKLSR 1068
Query: 65 RM--STRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHE------------ 110
R+ + R S + K + + NT++ S KK L+ E
Sbjct: 1069 RLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEPGV 1128
Query: 111 -----------NPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQ 159
N N Q + S+ ++Q T + + R +A + P +
Sbjct: 1129 ENVFEVSKTQDNRNNNSQQDIDSENMKQKTSATVQKDELRTCTADSKATAPAYKPGRGTG 1188
Query: 160 CSSTQSK-----SNKTSQKHVKRKVLEVKSDSKE-----------DENLVINEVINSPKG 203
+S K S T + H++ V ++ KE D V ++++P
Sbjct: 1189 VNSNSEKHADHRSTLTKKMHIQSAVSKMNPGEKEPIHRGTTEVNIDSETVHRMLLSAPSE 1248
Query: 204 KKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMK 263
R ++ A QG T VT R V+P
Sbjct: 1249 NDRVQKNLKNTAAEEHVAQGDATLEHSTNLDSSPSLSSVTVVPLRESYDPDVIPL---FD 1305
Query: 264 KSVHTQVNTNTTLPKSPQPSVPEQS----DNELEQAGKSKRG 301
K + +T +T P + ++P QS ++E+ + SK G
Sbjct: 1306 KRTVLEGSTASTSP-ADHSALPNQSLTVRESEVLKTSDSKEG 1346
Score = 33.5 bits (75), Expect = 0.84
Identities = 49/302 (16%), Positives = 115/302 (38%), Gaps = 25/302 (8%)
Query: 4 IQEKSKENSSK-VTKKSDDKNSETEIQDSQKNLAKKSGPK-----------ETIKSQAKS 51
++ + +E ++K T DK TE DS+K K K ET S A S
Sbjct: 924 VETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHS 983
Query: 52 SSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHEN 111
+ + ++ +L ++ K+ + +T+ K + + S + + K + +K +
Sbjct: 984 TQKDSSHRAKLP--LAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSD 1041
Query: 112 PKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTS 171
K ++++ ++ + + + + L R + + ++ Q + +++ ++T S + +S
Sbjct: 1042 DKDGKEVDSSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSS 1101
Query: 172 QKHVKRK----VLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKC 227
+ K+ ++ + + D + V K + + + S Q +
Sbjct: 1102 LQRPKKSGDMTLIPEQEPMEIDSEPGVENVFEVSKTQDNRNNNSQQDIDSENMKQKTSAT 1161
Query: 228 PQKTTRRDETKPVPVTSEVKRSKMATSV-------VPKKNEMKKSVHTQVNTNTTLPKSP 280
QK R T T+ + T V ++ + K +H Q + P
Sbjct: 1162 VQKDELRTCTADSKATAPAYKPGRGTGVNSNSEKHADHRSTLTKKMHIQSAVSKMNPGEK 1221
Query: 281 QP 282
+P
Sbjct: 1222 EP 1223
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 52.8 bits (125), Expect = 1e-06
Identities = 82/402 (20%), Positives = 173/402 (43%), Gaps = 39/402 (9%)
Query: 2 MSIQEKSKENSSKVTK-KSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP 60
++ +++SK S + T+ +SD K S+ I+ + K+ + K + KS S SK ++
Sbjct: 178 ITTKKRSKSRSKERTRHRSDKKKSKGGIE-----IVKEKTTRSKSKERKKSKSPSKRSKS 232
Query: 61 ELETRMS-TRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLN 119
+ + R S + + + S +K K+ + V+ +S K + +++E+ +
Sbjct: 233 QDQARKSKSPTLRRRSQEKIGKARSPTDDKVK-IEDKSKSKDRKKSPIINESRSRDRGKK 291
Query: 120 RRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKH----V 175
RS + RRS RS+E + + + P K ++ K N++ +
Sbjct: 292 SRSPVDLRGKSKDRRS-RSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSP 350
Query: 176 KRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRD 235
KR+ L K K + + ++N + K+ K +T ++ E+ ++ RR
Sbjct: 351 KRRSLSPKPRDKSRRSR--SPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRR 408
Query: 236 ETKP-----VPVTSEVKRSKMATSV---VPKKNEMKKSVHTQVNTNTTLPKSP--QPSVP 285
+ P + S +RSK A+ + P + + + + + +SP + P
Sbjct: 409 LSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSP 468
Query: 286 EQSD------NELEQAGKSKRG----SILQLCEEIAGEIESDNVEVKKESSQMESVK--- 332
+ D + L + +S+ G S ++ E+ S+ ++V++ESS ++++
Sbjct: 469 RRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLEDFD 528
Query: 333 -EEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKP 373
EE+ E +E+ ++RQ + QK N PS + P
Sbjct: 529 VEEEDEEALIEQRRIQRQAIVQKYKYLAEDSNMSVPSEPSSP 570
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 52.4 bits (124), Expect = 2e-06
Identities = 76/382 (19%), Positives = 159/382 (41%), Gaps = 36/382 (9%)
Query: 10 ENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTR 69
EN S + K + + + ++ L K+ ++ K + + K + + E + +
Sbjct: 1561 ENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1620
Query: 70 SSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLT 129
S + SN+ + I VR QE K S + E K QL Q ++++
Sbjct: 1621 SYENVSNE--AERIQHVVEAVRQEKQELYGKLRSTEANKKETEK---QLQEAEQEMEEMK 1675
Query: 130 EVSRRSLRSR-----EIQGQVQAVKQSLPPT--KKEQCSSTQSKSNKTSQKHVKRKVLEV 182
E R+ +S+ E++ + ++ + P ++C T SN + ++ ++R +E
Sbjct: 1676 EKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEY 1735
Query: 183 KSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCT---------------QGSEKC 227
++ SK+ ++L+ + +S + + ++HQ S Q +G++
Sbjct: 1736 ETLSKKFQSLMSEK--DSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSI 1793
Query: 228 PQKTTRRDE----TKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPS 283
P +T +D T+P + V +K A V K ++ + L +
Sbjct: 1794 PGETEEQDSLSMSTRPT-CSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGL 1852
Query: 284 VPEQSDN-ELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLE 342
E+ N E Q ++++ ++L GE++ EV K + + ++EE KL+
Sbjct: 1853 EEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLK 1912
Query: 343 ETS-VERQILHQKETNQDVQCN 363
ET+ E+ L ++ NQ + N
Sbjct: 1913 ETAEEEKDDLEERLMNQLAELN 1934
Score = 49.3 bits (116), Expect = 1e-05
Identities = 109/548 (19%), Positives = 223/548 (40%), Gaps = 83/548 (15%)
Query: 5 QEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELET 64
QEK + + +++ K +E ++Q++++ + + KE ++ AKS + + E
Sbjct: 1641 QEKQELYGKLRSTEANKKETEKQLQEAEQEMEEM---KEKMRKFAKSKQQKILELEEEND 1697
Query: 65 RMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQR 124
R+ R+ + D A K + S S K++L + K+ +E L+++ Q
Sbjct: 1698 RL--RAEVHPAGDTA-----KECMETLLSSNASMKEELERVKMEYET------LSKKFQS 1744
Query: 125 LQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKS 184
L +S + S E+Q ++ ++ +K+ +T+ N+T+ + +
Sbjct: 1745 L-----MSEKDSLSEEVQDLKHQIEGNV--SKQANLEATEKHDNQTNV--TEEGTQSIPG 1795
Query: 185 DSKEDENLVIN------EVINSPKGKKRKVE-----HQTACACSSQCTQGSEKCPQKTTR 233
+++E ++L ++ E + S K V H Q Q E+
Sbjct: 1796 ETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEE 1855
Query: 234 RDETKPVPVTSEVKRS-------------KMATSVVPKKNEMKKSVHTQVNTNTTLPKSP 280
+ + K T E +++ KM V K N + + + +++ T L ++
Sbjct: 1856 KQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETA 1915
Query: 281 QPSVPEQSDNELEQAGKSKRGSILQLCEEIAGE------IESDNVEVKKESSQMESVKEE 334
+ + + + Q + GSI C+++ +ES+ +KK S++E EE
Sbjct: 1916 EEEKDDLEERLMNQLAELN-GSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE---EE 1971
Query: 335 KPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKI 394
K +K E+T VE +I +KE + +Q + P K S AK+ K
Sbjct: 1972 KQQLVK-EKTKVESEI--RKEYLEKIQGAQKEPGNK------------SHAKELQELLKE 2016
Query: 395 KLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLH-DRNITCQQE 453
K + +Q + + Q K+ L + ALE +Q TK + + + +++
Sbjct: 2017 KQQEVKQLQKDCIRYQ--EKISALERTVK--ALEFVQTESQKDLEITKENLAQAVEHRKK 2072
Query: 454 KMKEINSEEVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFS 513
E+ S +V ++D E + +N L E++ + + +QMK D +
Sbjct: 2073 AQAELASFKVLLDDTQSEAARV---LADNLKLKKELQSNKESVKSQMKQK-DEDLERRLE 2128
Query: 514 QCLESKLE 521
Q E L+
Sbjct: 2129 QAEEKHLK 2136
Score = 45.1 bits (105), Expect = 3e-04
Identities = 71/351 (20%), Positives = 149/351 (42%), Gaps = 19/351 (5%)
Query: 4 IQEKSKENSSKVTKKSDDKNSE--TEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPE 61
++E+ ++ + TK + E +IQ +QK KS KE + + E K +
Sbjct: 1968 LEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVK----Q 2023
Query: 62 LETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRR 121
L+ K ++ ++ K++ + T E TK+ L+Q V KA +L
Sbjct: 2024 LQKDCIRYQEKISALERTVKAL-EFVQTESQKDLEITKENLAQA--VEHRKKAQAELASF 2080
Query: 122 SQRLQQLTEVSRRSLRSR-EIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVK-RKV 179
L + R L +++ ++Q+ K+S+ K++ + + + +KH+K +K
Sbjct: 2081 KVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2140
Query: 180 LEVKSDSKEDENLVINEVINSPK---GKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDE 236
++ K D+ E + + E I + KK K Q S TQ + ++ +D+
Sbjct: 2141 MQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDD 2200
Query: 237 TKPVPVTSEVKRSKMATSVVPKKNEMK-KSVHTQVNTNTTLPKSPQPSVPEQSDNELE-- 293
V ++ K + ++ K+ E++ K + V + S + + + LE
Sbjct: 2201 RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHD 2260
Query: 294 -QAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEI-KLE 342
Q +SK + +QL +++ ++ +N E+ + + + E+ KLE
Sbjct: 2261 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLE 2311
Score = 35.4 bits (80), Expect = 0.22
Identities = 90/467 (19%), Positives = 190/467 (40%), Gaps = 79/467 (16%)
Query: 25 ETEIQDSQKNLAKKSGP-KETIKSQAKS-SSESKINQPELETRMSTRSSKAASNDKATKS 82
E E+ QK AKK G ++ +K + K ++ I + E ET + A + +
Sbjct: 2659 EEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQK 2718
Query: 83 INKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQR----LQQLTEVSRRSLRS 138
+ T +G + + S L + ANE+L+ ++ L++L ++ + L +
Sbjct: 2719 LLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLN 2778
Query: 139 REIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLV--INE 196
RE + S+ T++ S + + + K ++L + S ++ N V ++
Sbjct: 2779 RERDALLSETAFSMNSTEENSLSHLEKLNQQLLSK--DEQLLHLSSQLEDSYNQVQSFSK 2836
Query: 197 VINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVV 256
+ S + ++ + ++ + + SE+ Q++ + T P V S K +S+
Sbjct: 2837 AMASLQNERDHLWNEL------EKFRKSEEGKQRSAAQPSTSPAEVQS---LKKAMSSLQ 2887
Query: 257 PKKNEMKKSV------HTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEI 310
++ + K + + Q+N T + + E D K+K I+Q
Sbjct: 2888 NDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQD-------KTKAFQIMQ----- 2935
Query: 311 AGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRK 370
E+ +N+ + E Q +++E++S E +H++ + S K
Sbjct: 2936 -EELRQENLSWQHELHQ-----------LRMEKSSWE---IHERRMKEQY---LMAISDK 2977
Query: 371 TKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMH 430
+ + + N I +S +K VQ+ + Q SP+ TS SP +
Sbjct: 2978 DQQLSHLQNLIRELRSSSSQTQPLK------VQYQR---QASPE-----TSASPDGSQ-- 3021
Query: 431 HPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTE 477
+ V ++ L T+L+D +KEI+ +E++I + ++ E
Sbjct: 3022 NLVYETELLRTQLND--------SLKEIHQKELRIQQLNSNFSQLLE 3060
Score = 35.0 bits (79), Expect = 0.29
Identities = 86/579 (14%), Positives = 228/579 (39%), Gaps = 56/579 (9%)
Query: 4 IQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELE 63
+ + E +++ + D ET+++ + L + + +QA +E + L+
Sbjct: 206 LSQTQAEQAAQQVVREKDARFETQVRLHEDELLQ-------LVTQADVETEMQQKLRVLQ 258
Query: 64 TRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQ 123
++ + + + +T + ++L Q + H + + R
Sbjct: 259 RKLEEHEESLVGRAQVVDLLQQE-LTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREES 317
Query: 124 RL---QQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL 180
++ + EV+ R L +Q ++ + + + Q + +S+ + QKH
Sbjct: 318 KILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQ-AELESRYSALEQKH------ 370
Query: 181 EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV 240
K++ +E + +++ +K + AC + Q S+ K + ++
Sbjct: 371 --KAEMEEKTSHILS---------LQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQT 419
Query: 241 PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLP---KSPQPSVPEQSDNELEQAG- 296
E + + + + N + H + + T+ P +V E++ L++
Sbjct: 420 IQQLEDQLQQKSKEISQFLNRLPLQQH-ETASQTSFPDVYNEGTQAVTEENIASLQKRVV 478
Query: 297 --KSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSV----ERQI 350
++++G++L E+ E++++N ++ + + +E+ + ++ E S+ ++
Sbjct: 479 ELENEKGALLLSSIELE-ELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRS 537
Query: 351 LHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLS--KFNSVQHNKLD 408
+E+ QDV N F S+K K + +L + A++ + K++L + H LD
Sbjct: 538 SSAEESGQDVLENTF--SQKHKELSVLLLEMKE-AQEEIAFLKLQLQGKRAEEADHEVLD 594
Query: 409 SQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEIN-----SEEV 463
+ ++ +P +++ T F + ++ +++ SEE+
Sbjct: 595 QKEMKQME--GEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEI 652
Query: 464 KINDITVEINKTTERAPENCHLANEI-KPSDPPLDNQMKHSFDSASNKNFSQCLESKLEN 522
+ND VE+ T + ++ +I + L+ + N + +Q + K +
Sbjct: 653 SLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLD 712
Query: 523 SPVENVTAASTLLSQAK--IDTGENKFPGSAPQQHSILS 559
+ ++ + L+ + K D + F + ++ +LS
Sbjct: 713 EKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLS 751
Score = 35.0 bits (79), Expect = 0.29
Identities = 116/591 (19%), Positives = 225/591 (38%), Gaps = 79/591 (13%)
Query: 6 EKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKS---GPKETIKSQAKSSSESKINQPEL 62
E +K + + KK D + + I++ + + + S K ++ K S +I +
Sbjct: 874 EITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKE 933
Query: 63 ETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHE---NPKANEQLN 119
+ + +R+ +A ++ + ++ + Y + S ++S+++L HE K NEQ
Sbjct: 934 QLNLLSRAEEA-KKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRK 992
Query: 120 RRSQ-----RLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKT-SQK 173
R+ Q R + L VSR E+ K+ +P ++ E+ + K NK S+K
Sbjct: 993 RKLQAALINRKELLQRVSR---LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEK 1049
Query: 174 HVKRKVLEVKSDSKE--DENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKT 231
V K E++ K+ E V + I +K E Q A Q Q
Sbjct: 1050 CVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQ-ALVKQMNQ--------- 1099
Query: 232 TRRDETKPVP-VTSEVKRSK-MATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSD 289
T +D+T + + +E+ ++ + ++ + + T + P E
Sbjct: 1100 TLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWK 1159
Query: 290 NELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQ 349
ELE+ + QL +++ + S +KK + ++EE + K + ++ Q
Sbjct: 1160 PELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQ-KDDYNRLQEQ 1218
Query: 350 ILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDS 409
Q + N+ N + +++ S +
Sbjct: 1219 FDEQSKENE-----------------------NIGDQLRQLQIQVRESIDGKLPSTDQQE 1255
Query: 410 QVSPKLGLLRTSFSPPALEMHH--PVTQSTFL-GTKLHDRNITCQQ---------EKMKE 457
S GL F A E HH PV +S H + + Q ++KE
Sbjct: 1256 SCSSTPGLEEPLFK--ATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKE 1313
Query: 458 INSE----EVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFS 513
I +E E+K++ T E+ K +E E L +I +++ S ++ + +
Sbjct: 1314 IEAEKVELELKVSSTTSELTKKSE---EVFQLQEQINKQGLEIESLKTVSHEAEVH---A 1367
Query: 514 QCLESKLENSPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSK 564
+ L+ KLE+S ++ Q K+D + K + S LS Q S+
Sbjct: 1368 ESLQQKLESSQLQIAGLEHLRELQPKLDELQ-KLISKKEEDVSYLSGQLSE 1417
Score = 33.5 bits (75), Expect = 0.84
Identities = 59/342 (17%), Positives = 141/342 (41%), Gaps = 31/342 (9%)
Query: 22 KNSETEIQDSQKNLAKKSGPKE-TIKSQAKSSSESKINQPELETRMSTRSSKAASNDKAT 80
K+ T++ +S + ++ G E I+ Q SK + +LET + + +
Sbjct: 2318 KDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEI 2377
Query: 81 KSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSRE 140
+ +++ +E+ + +++ + H+ + E N SQ ++ + + ++ +
Sbjct: 2378 NMKEQKIISLLSGKEEAIQVAIAELRQQHDK-EIKELENLLSQEEEENIVLEEENKKAVD 2436
Query: 141 IQGQVQAVKQSLPPTKKEQCSSTQS--KSNKTSQKHVKRKVLEVKSDSKEDENLVI--NE 196
Q+ +++ +Q + S KS + Q R V + + + ++++ ++
Sbjct: 2437 KTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQ 2496
Query: 197 VINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEV--KRSKMATS 254
+I + K++ + S SE + +E+ R +
Sbjct: 2497 LIQEAAAENNKLKEEIRGLRSHMDDLNSENAK-------------LDAELIQYREDLNQV 2543
Query: 255 VVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEE---IA 311
+ K ++ K+ + Q+ N L + + E+ E E+A + R S L EE ++
Sbjct: 2544 ITIKDSQQKQLLEVQLQQNKELEN--KYAKLEEKLKESEEANEDLRRSFNALQEEKQDLS 2601
Query: 312 GEIESDNVEVKKESSQMESVKEEKP-----TEIKLEETSVER 348
EIES V + + + Q+ +++EE ++K++E V R
Sbjct: 2602 KEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHR 2643
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 52.4 bits (124), Expect = 2e-06
Identities = 114/610 (18%), Positives = 226/610 (37%), Gaps = 88/610 (14%)
Query: 7 KSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRM 66
+ + S ++ + T + + A++ + ++ +S + S + +
Sbjct: 581 RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSP 640
Query: 67 STRSSKAASNDKATKSINKN-TVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR--RSQ 123
+ RS ++ S A + +++ T RG S+ T + S + + +R R
Sbjct: 641 ARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRG 700
Query: 124 RLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVK 183
R + + V R SR Q + ++ S +K + ++Q +S S +K+ +
Sbjct: 701 RSRSRSLVRRGRSHSRTPQRRGRSGSSS---ERKNKSRTSQRRSRSNSSPEMKKS----R 753
Query: 184 SDSKEDENLVINEVINSPKGK-KRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPV 242
S+ +L +SP+ K K ++ + + + SS C + + P + +R ++P
Sbjct: 754 ISSRRSRSL------SSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAK 807
Query: 243 TSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGS 302
+ R ++S P K + K ++++ PK + P Q QA +
Sbjct: 808 SRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTP 867
Query: 303 ILQLCEEIAGEIE-------------SDNVEVKKESSQMESVKEEKPTEIKLEETSVERQ 349
+ C E + + E S VK + +S + K++ RQ
Sbjct: 868 QRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQ 927
Query: 350 ILHQKETNQDVQCNRFFPSR---KTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNK 406
H ++ PSR +T P + + S SN L +++ +
Sbjct: 928 RSHSGSSSPS-------PSRVTSRTTPRR------SRSVSPCSNVESRLLPRYSHSGSSS 974
Query: 407 LDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKIN 466
D++V P+ R S S ++ + V T G L C QEK K+
Sbjct: 975 PDTKVKPETP-PRQSHS-GSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKD--------- 1023
Query: 467 DITVEINKTTERAPENCHLANEIKPSDPPLDN-------QMK--------HSFDSAS--- 508
+ P + L +K S PP ++ Q+K H D++S
Sbjct: 1024 -------SLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEV 1076
Query: 509 --NKNFSQCLESKLENSPVENVTAAST----LLSQAKIDTGENKFPGSAPQQHSILSNQT 562
+ + S L+SK + SP + +S+ L S++ I +F S + + Q+
Sbjct: 1077 RQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQS 1136
Query: 563 SKSSDNRETP 572
SD+ P
Sbjct: 1137 RFQSDSSSYP 1146
Score = 40.8 bits (94), Expect = 0.005
Identities = 132/654 (20%), Positives = 217/654 (33%), Gaps = 98/654 (14%)
Query: 5 QEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKK----------SGPKETIKSQA-KSSS 53
Q +S+ NSS KKS + + S ++ AK S P KSQ S
Sbjct: 738 QRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRS 797
Query: 54 ESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHE--- 110
S +QP+ ++R R S+++S+ + T + + +S S K+ +
Sbjct: 798 RSGSSQPKAKSRTPPRRSRSSSSPPPKQ--KSKTPSRQSHSSSSPHPKVKSGTPPRQGSI 855
Query: 111 -NPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNK 169
+P+ANEQ + QR L+SR + S PP K QS S
Sbjct: 856 TSPQANEQ-SVTPQRRSCFESSPDPELKSR--TPSRHSCSGSSPPRVKSSTPPRQSPSRS 912
Query: 170 TSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQ 229
+S + + ++ + S + + S +R ++ CS+ ++ +
Sbjct: 913 SSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRS---RSVSPCSNVESRLLPRYSH 969
Query: 230 KTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSD 289
+ +TK P T + + S PK V Q +L S P E+S
Sbjct: 970 SGSSSPDTKVKPETPPRQSHSGSISPYPK-------VKAQTPPGPSLSGSKSPCPQEKSK 1022
Query: 290 NELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQ 349
+ L Q S GS L LC + S Q++ + P + + + +S E +
Sbjct: 1023 DSLVQ---SCPGS-LSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP-DHRSDTSSPEVR 1077
Query: 350 ILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDS 409
H + PS ++K S
Sbjct: 1078 QSHSES-----------PSLQSK------------------------------------S 1090
Query: 410 QVSPKLGLLRTSFSPPALEMHHPVTQ--STFLGTKLHDRNITCQQEKMKEINSE--EVKI 465
Q SPK G R+S L P+ Q F + + ++ +Q + + +S V
Sbjct: 1091 QTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDS 1150
Query: 466 NDITVEINKTTERAPENCHL-ANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSP 524
N + + T + E L E + PP F S + L P
Sbjct: 1151 NSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPP 1210
Query: 525 VENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHL 584
E A S+ +T E Q L KS E P L +S L
Sbjct: 1211 RERSGAGSS------PETKEQNSALPTSSQDEELMEVVEKS----EEPAGQILSHLSSEL 1260
Query: 585 -EITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQH 637
E++ E E+ L +D Q + + V M + P +H
Sbjct: 1261 KEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEH 1314
Score = 38.9 bits (89), Expect = 0.020
Identities = 57/289 (19%), Positives = 119/289 (41%), Gaps = 27/289 (9%)
Query: 3 SIQEKSKENSSKV-TKKSDDKNS---ETEIQDSQKNLAKKSGPKETIKSQAKSSSESKIN 58
S E S E+ K T + ++S +T+ + + + +S P+ T K++ S S +
Sbjct: 1653 SSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASS 1712
Query: 59 QPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQL 118
PE +R R ++ S + + K+ + R S S + K + ++ +PK
Sbjct: 1713 SPETRSRTPPRHRRSPS-VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771
Query: 119 NRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTK----------KEQCSSTQSKSN 168
RS+ ++ T +RR RS Q + ++S ++ S + +S+
Sbjct: 1772 RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESS 1831
Query: 169 KTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCP 228
+TS + + + + K + SP KR + A + + + P
Sbjct: 1832 RTSSRRRRGRSRTPPTSRKRSRSR------TSPAPWKR----SRSRASPATHRRSRSRTP 1881
Query: 229 QKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLP 277
+ RR ++ PV+ +RS+ TSV +++ + S ++ + + P
Sbjct: 1882 LISRRRSRSRTSPVSR--RRSRSRTSVTRRRSRSRASPVSRRRSRSRTP 1928
Score = 37.0 bits (84), Expect = 0.076
Identities = 63/298 (21%), Positives = 106/298 (35%), Gaps = 34/298 (11%)
Query: 7 KSKENSS--KVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELET 64
+ E+SS + KKS K +S+K + PK KS+ K S+ P ++
Sbjct: 198 RRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKS 257
Query: 65 RMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQR 124
R + RS+ A S + S +++ S K L +P + RR +
Sbjct: 258 RRAHRSTSADSASSSDTSRSRS---------RSAAAKTHTTALAGRSP--SPASGRRGEG 306
Query: 125 LQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKS 184
+E G + S P T +Q SS +K K K S
Sbjct: 307 DAPFSE-----------PGTTSTQRPSSPETATKQPSSPYEDKDKDK----KEKSATRPS 351
Query: 185 DSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTS 244
S E + +P +R A ++ +Q P + + + P
Sbjct: 352 PSPERSSTGPEPPAPTPLLAERHGGSPQPLA-TTPLSQEPVNPPSEASPTRDRSPPKSPE 410
Query: 245 EVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGS 302
++ +S + S P K S H ++ P+SP+P+ S E+ + SK S
Sbjct: 411 KLPQSSSSESSPPSPQPTKVSRHA-----SSSPESPKPAPAPGSHREISSSPTSKNRS 463
Score = 34.7 bits (78), Expect = 0.38
Identities = 48/262 (18%), Positives = 103/262 (39%), Gaps = 14/262 (5%)
Query: 5 QEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELET 64
+ +S+ ++ T++ D S S++ +S + T + + S S+ + +
Sbjct: 1774 RSRSRREKTRTTRRRDRSGSSQST--SRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESS 1831
Query: 65 RMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKK-LVHENPKANEQLNRRSQ 123
R S+R + S T + T S K+ S+ H ++ L R +
Sbjct: 1832 RTSSRRRRGRSRTPPTSRKRSRSRT----SPAPWKRSRSRASPATHRRSRSRTPLISRRR 1887
Query: 124 RLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVK 183
+ + VSRR RSR + ++ ++ P +++ S T + + S+ + +
Sbjct: 1888 SRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRS--RTPTTRRR 1945
Query: 184 SDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVT 243
S S+ +P +R+ +T+ + + T RR ++ PVT
Sbjct: 1946 SRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITR---RRSRSRTSPVTRRRSRSRTSPVT 2002
Query: 244 SEVKRSKMATSVVPKKNEMKKS 265
+RS+ TS V ++ ++
Sbjct: 2003 R--RRSRSRTSPVTRRRSRSRT 2022
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 51.6 bits (122), Expect = 3e-06
Identities = 81/395 (20%), Positives = 153/395 (38%), Gaps = 59/395 (14%)
Query: 4 IQEKSKENSSKVTKKSDDKNSETEIQDSQKN----LAKKSGPKETIKSQAKSSSESKIN- 58
I+ K E + S D+N TE ++ + K+G E + + ++S I+
Sbjct: 460 IETKFYETKEESYSPSKDRNIITEGNGTESLNSVITSMKTGELEKETAPLRKDADSSISV 519
Query: 59 --------------QPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQ 104
PE+ET + + S A T + + T++G + KK +
Sbjct: 520 LEIHSQKAQIEEPDPPEMETSLDS-SEMAKDLSSKTALSSTESCTMKGEEKSPKTKKDKR 578
Query: 105 KKLVHENPKANEQ----LNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQC 160
++ K + L++ +QRL + E +S E G +A + S P + C
Sbjct: 579 PPILECLEKLEKSKKTFLDKDAQRLSPIPEEVPKSTLESEKPGSPEAAETSPPSNIIDHC 638
Query: 161 SSTQSK--------SNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQT 212
S+ ++ + VK+ LE KED E+ N + +E +
Sbjct: 639 EKLASEKEVVECQSTSTVGGQSVKKVDLET---LKEDSEFTKVEMDNLDNAQTSGIEEPS 695
Query: 213 ACACSSQCTQGSEKC--PQKTTRRDETK------------PVPVTSEVKRSKMATSVVPK 258
S Q ++ K ++TT + T+ + ++S K+ V+
Sbjct: 696 ETKGSMQKSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKPDSPPKVLEP 755
Query: 259 KNEMKKSVHTQVNTNT--TLPKSPQPSVPEQSDNEL-EQAGKSKRGSILQLCEEIAGEIE 315
+N+ +K+ + TN TL +SP+ S P E+ +Q KRG E E+E
Sbjct: 756 ENKQEKTEKEEEKTNVGRTLRRSPRISRPTAKVAEIRDQKADKKRG-------EGEDEVE 808
Query: 316 SDNVEVKKESSQMESVKEEKPTEIKLEETSVERQI 350
++ ++K + K EK T K+ + + ++
Sbjct: 809 EESTALQKTDKKEILKKSEKDTNSKVSKVKPKGKV 843
Score = 32.0 bits (71), Expect = 2.5
Identities = 47/222 (21%), Positives = 96/222 (43%), Gaps = 28/222 (12%)
Query: 290 NELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIK-------LE 342
N +Q S+ L+ EE E E+ E +KES +M+S EE+P +++ LE
Sbjct: 216 NSSQQDNSSRESPSLE-DEETKKEEETPKQEEQKESEKMKS--EEQPMDLENRSTANVLE 272
Query: 343 ETSVERQILHQKETNQ---DVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKF 399
ET+V+++ +KE + V+ + P + K I+ + S K+N K+++ +
Sbjct: 273 ETTVKKEKEDEKELVKLPVIVKLEKPLPENEEKK---IIKEESDSFKENVKPIKVEVKEC 329
Query: 400 NSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEIN 459
+ + S P + P +E + S + K T + EK+K
Sbjct: 330 RADPKDTKSSMEKP------VAQEPERIEFGGNIKSSHEITEK-----STEETEKLKNDQ 378
Query: 460 SEEVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMK 501
++ + ++++ + +P L + P+ L +++K
Sbjct: 379 QAKIPLKKREIKLSDDFD-SPVKGPLCKSVTPTKEFLKDEIK 419
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 51.6 bits (122), Expect = 3e-06
Identities = 70/430 (16%), Positives = 172/430 (40%), Gaps = 32/430 (7%)
Query: 9 KENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMST 68
++ ++T E D + + K+ E +++ +S E+ N L +R +T
Sbjct: 754 RKRERELTALKGALKEEVSSHDQEMDKLKEQYDAE-LQALRESVEEATKNVEVLASRSNT 812
Query: 69 RSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHE----NPKANEQLNRRSQR 124
A + K + + ++G S+E ++ ++ + + KA E L +
Sbjct: 813 SEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGE 872
Query: 125 LQQLTEVSRRSLRS--------REIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVK 176
++QL E + + R ++ +++A + +L T +EQ ++ ++ QK
Sbjct: 873 IRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQL 932
Query: 177 RKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRD- 235
R++ + E+E + + I K +K + A S+ Q ++ RR+
Sbjct: 933 RRL----KNEMENERWHLGKTIE--KLQKEMADIVEASRTSTLELQNQLDEYKEKNRREL 986
Query: 236 -----ETKPVPVTSEVKR---SKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQ 287
+ K + +E R KM + + E++ Q T Q +
Sbjct: 987 AEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLE 1046
Query: 288 SDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVE 347
+ E + K R +++ E+ ++E + E + S + E+ + + + +
Sbjct: 1047 YELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLS----ERISRSREQMEQLR 1102
Query: 348 RQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKL 407
++L ++ QD++C++ R+ K +K + + S + + +++ + ++L
Sbjct: 1103 NELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRL 1162
Query: 408 DSQVSPKLGL 417
+S+ + L
Sbjct: 1163 ESEERDRANL 1172
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 51.2 bits (121), Expect = 4e-06
Identities = 77/375 (20%), Positives = 147/375 (39%), Gaps = 57/375 (15%)
Query: 14 KVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETR-------M 66
KV +K +DK +TE ++ +K ++ KE K K + E E R
Sbjct: 513 KVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGR 572
Query: 67 STRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQ 126
T +S+ + T+S+ + +T++ E P + E + S+ +
Sbjct: 573 KTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPE-PISTEPV-ETSRWTE 630
Query: 127 QLTEVSRRSLRSREIQGQVQAVKQSLPPTKKE-QCSS--------------TQSKSNKTS 171
+ EV+++ L G+ A + TK E QC + Q KTS
Sbjct: 631 EEMEVAKKGLVE---HGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTS 687
Query: 172 QK-HVKRKVLEVKS-----DSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSE 225
+K +R V + +S ++EDE++ + +P+ + + + SE
Sbjct: 688 RKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSE------------VEAVKPSE 735
Query: 226 KCPQKTTRRDETKPV----PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQ 281
P+ T R T+P P T + + +V K +SV TQVN + + + Q
Sbjct: 736 DSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQ 795
Query: 282 PSVPEQSDNELEQA-----GKSKRGSI---LQLCEEIAGEIESDNVEVKKESSQMESVKE 333
V +Q + E + +K S+ +++ E A ++E DN + + E V+
Sbjct: 796 MDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEP 855
Query: 334 EKPTEIKLEETSVER 348
+ ++ + +R
Sbjct: 856 RDEDLVVAQQINAQR 870
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 51.2 bits (121), Expect = 4e-06
Identities = 65/299 (21%), Positives = 108/299 (36%), Gaps = 37/299 (12%)
Query: 3 SIQEKSKENSSKVTKKSDDKNS--------ETEIQDSQKNLAKKSG-PKETIKSQAKSSS 53
S S +SS + K KNS + +++D++KN KK PK + +A S
Sbjct: 126 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGL 185
Query: 54 ES---KINQPELETRMSTRSSKAASNDKAT--KSINKNTVTVRGYSQESTKKKLSQKKLV 108
++ K+ P+ T T+ +K +++ K T K IN ++ S S + L+ K
Sbjct: 186 DNGDFKVTTPDTST---TQHNKVSTSPKITTAKPINPRP-SLPPNSDTSKETSLTVNKET 241
Query: 109 HENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSN 168
K N+++ T+ ++ ++E Q + + L PT K T
Sbjct: 242 TVETKETTTTNKQTS-----TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 296
Query: 169 KTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCP 228
T + + KE + +PK T S T E P
Sbjct: 297 TTKGPALTTPKEPTPTTPKEPAS-------TTPK-------EPTPTTIKSAPTTPKEPAP 342
Query: 229 QKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQ 287
T T P + K T P K+ T + T PK P P+ P++
Sbjct: 343 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401
Score = 48.1 bits (113), Expect = 3e-05
Identities = 60/283 (21%), Positives = 105/283 (37%), Gaps = 33/283 (11%)
Query: 31 SQKNLAKKSGPKETIKSQAKSSSE-------SKINQPELETRMSTRSSKAASNDKATKSI 83
S K SG +TIKS K S + K+ + E T + S S+ ++ S
Sbjct: 74 SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 133
Query: 84 NKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQG 143
+ +T+ S+ S + QKKL ++ K N + + + + E L + +
Sbjct: 134 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS-GLDNGDF-- 190
Query: 144 QVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVK-RKVLEVKSDSKEDENLVINEVINSPK 202
K + P T Q + + T+ K + R L SD+ ++ +L +N+
Sbjct: 191 -----KVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 245
Query: 203 GKKRKVEHQTAC-----ACSSQCTQGSEKCPQK------------TTRRDETKPVPVTSE 245
+ QT+ S++ TQ EK K T + + T P +
Sbjct: 246 KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 305
Query: 246 VKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQS 288
K T P K+ T + + T PK P P+ + +
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 348
Score = 41.2 bits (95), Expect = 0.004
Identities = 48/285 (16%), Positives = 108/285 (37%), Gaps = 37/285 (12%)
Query: 41 PKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKK 100
PKET + K + + +P T + +++ +T + K T+ EST +
Sbjct: 782 PKETAPTTPKEPAPTTPKKPAPTT---PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 838
Query: 101 KLSQK--KLVHENPKANEQLNRRSQRLQ--QLTEVSRRSLRSREIQGQVQAVKQSLPPTK 156
++ K + +PK ++ ++T ++ R+++ + + P
Sbjct: 839 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA-PKMT 897
Query: 157 KEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKED----------------------ENLVI 194
KE ++T+ KT++ + +V S + +D + +
Sbjct: 898 KETATTTE----KTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 953
Query: 195 NEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRS---KM 251
E++N P+ + + T ++ Q K P+K T + K +P + K + +
Sbjct: 954 TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1013
Query: 252 ATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAG 296
TS +P+ N + + T T ++P + E + + G
Sbjct: 1014 MTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG 1058
Score = 40.8 bits (94), Expect = 0.005
Identities = 61/300 (20%), Positives = 117/300 (39%), Gaps = 40/300 (13%)
Query: 10 ENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTR 69
++++K + K +K ++ +S++ + S + S + SSS S + R
Sbjct: 89 KSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSS---------STIR 139
Query: 70 SSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRL---- 125
K++ N A + + K + V+ + TKKK + K V + +A L+ ++
Sbjct: 140 KIKSSKNSAANRELQKK-LKVKDNKKNRTKKKPTPKPPVVD--EAGSGLDNGDFKVTTPD 196
Query: 126 QQLTEVSRRSLRSREIQGQVQAVKQSLPP---TKKEQC------SSTQSKSNKTSQKHVK 176
T+ ++ S + + + SLPP T KE ++ ++K T+ K
Sbjct: 197 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 256
Query: 177 RKVLEVKSDSKEDENL---------VINEVINSPKGKKRKVEHQTACACSSQCTQGSEKC 227
E + +KE +++ ++V+ P K A + T + K
Sbjct: 257 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 316
Query: 228 PQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQ 287
P TT ++ P P T +S T P K + T T K P P+ P++
Sbjct: 317 PASTTPKE---PTPTTI---KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 370
Score = 38.5 bits (88), Expect = 0.026
Identities = 46/210 (21%), Positives = 78/210 (37%), Gaps = 14/210 (6%)
Query: 149 KQSLPPTKKEQC-SSTQSKSNKTSQKHVKRKVLEVKSDSKE---DENLVINEVINSPKGK 204
K++ PP+ Q ST +S K K +KV+E + ++E EN + +S
Sbjct: 76 KKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSS 135
Query: 205 K--RKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVP-------VTSEVKRSKMATSV 255
RK++ A + + Q K R + KP P S + +
Sbjct: 136 STIRKIKSSKNSAANREL-QKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTT 194
Query: 256 VPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIE 315
V T T P +P+PS+P SD E + + + ++ E +
Sbjct: 195 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQ 254
Query: 316 SDNVEVKKESSQMESVKEEKPTEIKLEETS 345
+ +K +S E+ EK + L TS
Sbjct: 255 TSTDGKEKTTSAKETQSIEKTSAKDLAPTS 284
Score = 35.4 bits (80), Expect = 0.22
Identities = 60/276 (21%), Positives = 103/276 (37%), Gaps = 41/276 (14%)
Query: 209 EHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHT 268
E C C +QC + + CP + +EV TS K S +
Sbjct: 38 ERGRECDCDAQCKKYDKCCPDYES---------FCAEVHN---PTSPPSSKKAPPPSGAS 85
Query: 269 QVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQM 328
Q +TT +SP+P +++ +E EEI E +V +ESS
Sbjct: 86 QTIKSTT-KRSPKPPNKKKTKKVIES-------------EEIT---EEHSVSENQESSSS 128
Query: 329 ESVKEEKPT--EIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAK 386
S T +IK + S + L +K +D + NR +K P +++ S
Sbjct: 129 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNR--TKKKPTPKPPVVDEAGSGLD 186
Query: 387 KNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFL----GTK 442
K+ ++ QHNK+ + SPK+ + P+L + ++ T L T
Sbjct: 187 NGD--FKVTTPDTSTTQHNKVST--SPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT 242
Query: 443 LHDRNITCQQEKMKEINSEEVKINDITVEINKTTER 478
+ + T ++ E+ T I KT+ +
Sbjct: 243 VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 278
Score = 33.1 bits (74), Expect = 1.1
Identities = 33/140 (23%), Positives = 48/140 (34%), Gaps = 13/140 (9%)
Query: 149 KQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKV 208
K + P T KE +T + T+ K L+ + + + + KG
Sbjct: 714 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT 773
Query: 209 EHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHT 268
+ A + + K P TT + KP P T E P + S T
Sbjct: 774 SDKPAPTTPKETAPTTPKEPAPTTPK---KPAPTTPET----------PPPTTSEVSTPT 820
Query: 269 QVNTNTTLPKSPQPSVPEQS 288
TT+ KSP S PE S
Sbjct: 821 TTKEPTTIHKSPDESTPELS 840
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 51.2 bits (121), Expect = 4e-06
Identities = 65/299 (21%), Positives = 108/299 (36%), Gaps = 37/299 (12%)
Query: 3 SIQEKSKENSSKVTKKSDDKNS--------ETEIQDSQKNLAKKSG-PKETIKSQAKSSS 53
S S +SS + K KNS + +++D++KN KK PK + +A S
Sbjct: 167 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGL 226
Query: 54 ES---KINQPELETRMSTRSSKAASNDKAT--KSINKNTVTVRGYSQESTKKKLSQKKLV 108
++ K+ P+ T T+ +K +++ K T K IN ++ S S + L+ K
Sbjct: 227 DNGDFKVTTPDTST---TQHNKVSTSPKITTAKPINPRP-SLPPNSDTSKETSLTVNKET 282
Query: 109 HENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSN 168
K N+++ T+ ++ ++E Q + + L PT K T
Sbjct: 283 TVETKETTTTNKQTS-----TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 337
Query: 169 KTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCP 228
T + + KE + +PK T S T E P
Sbjct: 338 TTKGPALTTPKEPTPTTPKEPAS-------TTPK-------EPTPTTIKSAPTTPKEPAP 383
Query: 229 QKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQ 287
T T P + K T P K+ T + T PK P P+ P++
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442
Score = 48.1 bits (113), Expect = 3e-05
Identities = 60/283 (21%), Positives = 105/283 (37%), Gaps = 33/283 (11%)
Query: 31 SQKNLAKKSGPKETIKSQAKSSSE-------SKINQPELETRMSTRSSKAASNDKATKSI 83
S K SG +TIKS K S + K+ + E T + S S+ ++ S
Sbjct: 115 SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 174
Query: 84 NKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQG 143
+ +T+ S+ S + QKKL ++ K N + + + + E L + +
Sbjct: 175 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS-GLDNGDF-- 231
Query: 144 QVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVK-RKVLEVKSDSKEDENLVINEVINSPK 202
K + P T Q + + T+ K + R L SD+ ++ +L +N+
Sbjct: 232 -----KVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 286
Query: 203 GKKRKVEHQTAC-----ACSSQCTQGSEKCPQK------------TTRRDETKPVPVTSE 245
+ QT+ S++ TQ EK K T + + T P +
Sbjct: 287 KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 346
Query: 246 VKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQS 288
K T P K+ T + + T PK P P+ + +
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 389
Score = 41.2 bits (95), Expect = 0.004
Identities = 48/285 (16%), Positives = 108/285 (37%), Gaps = 37/285 (12%)
Query: 41 PKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKK 100
PKET + K + + +P T + +++ +T + K T+ EST +
Sbjct: 823 PKETAPTTPKEPAPTTPKKPAPTT---PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 879
Query: 101 KLSQK--KLVHENPKANEQLNRRSQRLQ--QLTEVSRRSLRSREIQGQVQAVKQSLPPTK 156
++ K + +PK ++ ++T ++ R+++ + + P
Sbjct: 880 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA-PKMT 938
Query: 157 KEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKED----------------------ENLVI 194
KE ++T+ KT++ + +V S + +D + +
Sbjct: 939 KETATTTE----KTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 994
Query: 195 NEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRS---KM 251
E++N P+ + + T ++ Q K P+K T + K +P + K + +
Sbjct: 995 TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1054
Query: 252 ATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAG 296
TS +P+ N + + T T ++P + E + + G
Sbjct: 1055 MTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG 1099
Score = 40.8 bits (94), Expect = 0.005
Identities = 61/300 (20%), Positives = 117/300 (39%), Gaps = 40/300 (13%)
Query: 10 ENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTR 69
++++K + K +K ++ +S++ + S + S + SSS S + R
Sbjct: 130 KSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSS---------STIR 180
Query: 70 SSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRL---- 125
K++ N A + + K + V+ + TKKK + K V + +A L+ ++
Sbjct: 181 KIKSSKNSAANRELQKK-LKVKDNKKNRTKKKPTPKPPVVD--EAGSGLDNGDFKVTTPD 237
Query: 126 QQLTEVSRRSLRSREIQGQVQAVKQSLPP---TKKEQC------SSTQSKSNKTSQKHVK 176
T+ ++ S + + + SLPP T KE ++ ++K T+ K
Sbjct: 238 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 297
Query: 177 RKVLEVKSDSKEDENL---------VINEVINSPKGKKRKVEHQTACACSSQCTQGSEKC 227
E + +KE +++ ++V+ P K A + T + K
Sbjct: 298 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 357
Query: 228 PQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQ 287
P TT ++ P P T +S T P K + T T K P P+ P++
Sbjct: 358 PASTTPKE---PTPTTI---KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 411
Score = 38.5 bits (88), Expect = 0.026
Identities = 46/210 (21%), Positives = 78/210 (37%), Gaps = 14/210 (6%)
Query: 149 KQSLPPTKKEQC-SSTQSKSNKTSQKHVKRKVLEVKSDSKE---DENLVINEVINSPKGK 204
K++ PP+ Q ST +S K K +KV+E + ++E EN + +S
Sbjct: 117 KKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSS 176
Query: 205 K--RKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVP-------VTSEVKRSKMATSV 255
RK++ A + + Q K R + KP P S + +
Sbjct: 177 STIRKIKSSKNSAANREL-QKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTT 235
Query: 256 VPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIE 315
V T T P +P+PS+P SD E + + + ++ E +
Sbjct: 236 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQ 295
Query: 316 SDNVEVKKESSQMESVKEEKPTEIKLEETS 345
+ +K +S E+ EK + L TS
Sbjct: 296 TSTDGKEKTTSAKETQSIEKTSAKDLAPTS 325
Score = 35.4 bits (80), Expect = 0.22
Identities = 60/276 (21%), Positives = 103/276 (37%), Gaps = 41/276 (14%)
Query: 209 EHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHT 268
E C C +QC + + CP + +EV TS K S +
Sbjct: 79 ERGRECDCDAQCKKYDKCCPDYES---------FCAEVHN---PTSPPSSKKAPPPSGAS 126
Query: 269 QVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQM 328
Q +TT +SP+P +++ +E EEI E +V +ESS
Sbjct: 127 QTIKSTT-KRSPKPPNKKKTKKVIES-------------EEIT---EEHSVSENQESSSS 169
Query: 329 ESVKEEKPT--EIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAK 386
S T +IK + S + L +K +D + NR +K P +++ S
Sbjct: 170 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNR--TKKKPTPKPPVVDEAGSGLD 227
Query: 387 KNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFL----GTK 442
K+ ++ QHNK+ + SPK+ + P+L + ++ T L T
Sbjct: 228 NGD--FKVTTPDTSTTQHNKVST--SPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT 283
Query: 443 LHDRNITCQQEKMKEINSEEVKINDITVEINKTTER 478
+ + T ++ E+ T I KT+ +
Sbjct: 284 VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 319
Score = 33.1 bits (74), Expect = 1.1
Identities = 33/140 (23%), Positives = 48/140 (34%), Gaps = 13/140 (9%)
Query: 149 KQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKV 208
K + P T KE +T + T+ K L+ + + + + KG
Sbjct: 755 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT 814
Query: 209 EHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHT 268
+ A + + K P TT + KP P T E P + S T
Sbjct: 815 SDKPAPTTPKETAPTTPKEPAPTTPK---KPAPTTPET----------PPPTTSEVSTPT 861
Query: 269 QVNTNTTLPKSPQPSVPEQS 288
TT+ KSP S PE S
Sbjct: 862 TTKEPTTIHKSPDESTPELS 881
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 51.2 bits (121), Expect = 4e-06
Identities = 94/459 (20%), Positives = 168/459 (36%), Gaps = 71/459 (15%)
Query: 6 EKSKENSSKVTKKSDDK--------NSETEIQDSQKNLAKKSGPKETIKS-----QAKSS 52
+KSK+ K D K N E++ +K + K +KS Q+K S
Sbjct: 116 KKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKS 175
Query: 53 SESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENP 112
S PE + T S + DK +K T T +++ + KK L + K N
Sbjct: 176 KSSSETNPESQ-NSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKT--SND 232
Query: 113 KANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQ 172
+E + S + L V + S ++ Q+ + + K K +
Sbjct: 233 PISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNA 292
Query: 173 KHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQC------TQGSEK 226
K E D+K+D V V K K K + ++ A S T+ +K
Sbjct: 293 KKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKK 352
Query: 227 CPQKTTRRDETKPVPVTSEV------------KRSKMATSVVPKKNEMKKSVHTQVNTNT 274
+K ++ +TK P +++ + K A+ KK + KK + + +
Sbjct: 353 KLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESE 412
Query: 275 TLPKSPQ------------------PSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIES 316
K Q + E +D + E G SK+G +E G+ +S
Sbjct: 413 LESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGK----KDEKKGKKDS 468
Query: 317 DNVEVKKESSQ-MESVKEEKPTEIKLEETSVERQILHQKETNQDVQCN------RFFPSR 369
+ KK++ + ES + E E+K ++ + + +K+ +D + + F S
Sbjct: 469 KKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESS 528
Query: 370 KTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLD 408
KT G +S K + T+ + S + K+D
Sbjct: 529 KT--------GFKTSTKIKGSDTESEESLYKPGAKKKID 559
Score = 51.2 bits (121), Expect = 4e-06
Identities = 63/276 (22%), Positives = 120/276 (43%), Gaps = 38/276 (13%)
Query: 6 EKSKENSSKVTKKSDDK----NSETEIQDSQ------KNLAKKSGPKETIKSQAKSSSES 55
+K K+ K KK D K +++TE D++ +NL KK+ + K AK + S
Sbjct: 348 KKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNL-KKASKNDDKKKDAKKITFS 406
Query: 56 KINQPELETRMSTRSSKAASNDKAT---KSINKNTVTV------RGYSQESTK-KKLSQK 105
++ ELE++ S + K D T KS+ + + +G S++ K +K +K
Sbjct: 407 TDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKK 466
Query: 106 KLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQS 165
++ K + + N S ++ E+ + S+E +G + +K+ ++ ST +
Sbjct: 467 DSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKD----ARKDTESTDA 522
Query: 166 KSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSE 225
+ +++S+ K SD++ +E+L G K+K++ + +S+ E
Sbjct: 523 EFDESSKTGFKTSTKIKGSDTESEESLY-------KPGAKKKIDESDGTSANSK----ME 571
Query: 226 KCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNE 261
K R +K T K K +T VP E
Sbjct: 572 GLESKRGFRMSSK--KTTFNEKGEKASTGRVPPSRE 605
Score = 49.3 bits (116), Expect = 1e-05
Identities = 84/399 (21%), Positives = 158/399 (39%), Gaps = 59/399 (14%)
Query: 7 KSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRM 66
K + + K TKK+ K+S+ E +DS+ AKK K +K K + K + +
Sbjct: 279 KYTKYTKKDTKKNAKKSSDAESEDSKD--AKKDSKK--VKKNVKKDDKKK------DVKK 328
Query: 67 STRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQ 126
T S+ A S D +K K+T + KKKL + + K E + S +
Sbjct: 329 DTESTDAESGD--SKDERKDT--------KKDKKKLKKDDKKKDTKKYPESTDTESGDAK 378
Query: 127 QLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSK-SNKTSQKHVKRKVLEVKSD 185
SR ++ + + + K+ T E S +SK S K +K K + K
Sbjct: 379 DARNDSRNLKKASKNDDKKKDAKKITFSTDSE--SELESKESQKDEKKDKKDSKTDNKKS 436
Query: 186 SKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSE 245
K DE + + PKG +K + EK +K +++D+ K
Sbjct: 437 VKNDEE--STDADSEPKGDSKK-------------GKKDEKKGKKDSKKDDKKK-DAKKN 480
Query: 246 VKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSK------ 299
+ ++M + + KK+ KK + + + K + E +D E +++ K+
Sbjct: 481 AESTEMESDLELKKD--KKHSKEKKGSKKDIKKDARKDT-ESTDAEFDESSKTGFKTSTK 537
Query: 300 -RGSILQLCEEI---AGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKE 355
+GS + E + + + D + +S+ME ++ ++ + ++T+ E
Sbjct: 538 IKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTF-------NE 590
Query: 356 TNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKI 394
+ R PSR+ P+ + S + W K+
Sbjct: 591 KGEKASTGRVPPSREKPPLPACEPSLPSPKVRRLCWCKM 629
Score = 47.0 bits (110), Expect = 7e-05
Identities = 61/296 (20%), Positives = 116/296 (39%), Gaps = 24/296 (8%)
Query: 5 QEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELET 64
++ K+ S + D K+ + + +K L K K+T K + +ES +
Sbjct: 324 KDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTES---GDAKDA 380
Query: 65 RMSTRS-SKAASNDKATKSINKNTVTVRGYSQ----ESTKKKLSQKKLVHENPKANEQLN 119
R +R+ KA+ ND K K T + S+ ES K + KK + K + + +
Sbjct: 381 RNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKND 440
Query: 120 RRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSN---KTSQKHVK 176
S + + + E +G+ + K K+ ST+ +S+ K +KH K
Sbjct: 441 EESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSK 500
Query: 177 RK---VLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKC--PQKT 231
K ++K D+++D E ++ + K +T+ T+ E P
Sbjct: 501 EKKGSKKDIKKDARKD-----TESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAK 555
Query: 232 TRRDETKPVPVTSEVK--RSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVP 285
+ DE+ S+++ SK + KK + + +T P +P +P
Sbjct: 556 KKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEK-GEKASTGRVPPSREKPPLP 610
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 51.2 bits (121), Expect = 4e-06
Identities = 72/341 (21%), Positives = 142/341 (41%), Gaps = 31/341 (9%)
Query: 5 QEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELET 64
++ S + SK +K S+ K S +S+ K+S ++ +SQ +S S S+ + +
Sbjct: 1818 RDSSLRSRSKRSKSSEHK-SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRS 1876
Query: 65 RMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQR 124
R +R ++ S +K K + R S+E +K+ S + +N K +R R
Sbjct: 1877 RSKSRGRRSVSKEK-----RKRSPKHRSKSRERKRKRSSSR----DNRKTVRARSRTPSR 1927
Query: 125 LQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKS 184
+ SRR RSR + G+ ++ S+ P+++ S T S+ ++T + + ++
Sbjct: 1928 RSRSHTPSRRR-RSRSV-GRRRSF--SISPSRR---SRTPSRRSRTPSRRSRTPSRRSRT 1980
Query: 185 DSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGS-----EKCPQKTTRRDETKP 239
S+ S + + R V + + + S + S + + RR ++
Sbjct: 1981 PSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRS 2040
Query: 240 VPVTSEVKR----SKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQA 295
KR K + K N V L +P P++ E+ +++
Sbjct: 2041 SERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEK---VAKKS 2097
Query: 296 GKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKP 336
G + + + C++IA E D+V V K + +EE+P
Sbjct: 2098 GGATIEELTEKCKQIAQSKEDDDVIVNK--PHVSDEEEEEP 2136
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 51.2 bits (121), Expect = 4e-06
Identities = 72/341 (21%), Positives = 142/341 (41%), Gaps = 31/341 (9%)
Query: 5 QEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELET 64
++ S + SK +K S+ K S +S+ K+S ++ +SQ +S S S+ + +
Sbjct: 1818 RDSSLRSRSKRSKSSEHK-SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRS 1876
Query: 65 RMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQR 124
R +R ++ S +K K + R S+E +K+ S + +N K +R R
Sbjct: 1877 RSKSRGRRSVSKEK-----RKRSPKHRSKSRERKRKRSSSR----DNRKTVRARSRTPSR 1927
Query: 125 LQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKS 184
+ SRR RSR + G+ ++ S+ P+++ S T S+ ++T + + ++
Sbjct: 1928 RSRSHTPSRRR-RSRSV-GRRRSF--SISPSRR---SRTPSRRSRTPSRRSRTPSRRSRT 1980
Query: 185 DSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGS-----EKCPQKTTRRDETKP 239
S+ S + + R V + + + S + S + + RR ++
Sbjct: 1981 PSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRS 2040
Query: 240 VPVTSEVKR----SKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQA 295
KR K + K N V L +P P++ E+ +++
Sbjct: 2041 SERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEK---VAKKS 2097
Query: 296 GKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKP 336
G + + + C++IA E D+V V K + +EE+P
Sbjct: 2098 GGATIEELTEKCKQIAQSKEDDDVIVNK--PHVSDEEEEEP 2136
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 50.8 bits (120), Expect = 5e-06
Identities = 108/528 (20%), Positives = 209/528 (39%), Gaps = 79/528 (14%)
Query: 132 SRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVK--RKVLEVKSDSKED 189
S+R + +E + + K + P + S++SK ++ + K +K K + V +
Sbjct: 41 SQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKESQKNDKDLKILEKEIRVLLQERGA 100
Query: 190 ENLVINEV----------INSPKGKKRKVEHQTACACSS--QCTQGSEKCPQKTTRRDET 237
++ I ++ +N+ +K + A + T+ +E K +
Sbjct: 101 QDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQ 160
Query: 238 KPVPVTS------EVKRSKMATSVVPKKNEMKKSVH-TQVNTNTTLPKSPQPSVPEQSDN 290
K + + S KR ++ K+ M+ + TQ + + K Q S
Sbjct: 161 KNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIE 220
Query: 291 ELEQAGKSKRGSILQLCEEIAGEIESDNVE-VKKESSQMESVKEEKPTEIKLEETSVERQ 349
+ + KS+ +L+ EEI+ SD VE K + +Q+E +EK EI + S+E
Sbjct: 221 KEKIDEKSETEKLLEYIEEIS--CASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEEN 278
Query: 350 ILHQKETNQDVQCNRFFPSRKTKPVKCIL------NGINSSAKKNSNWTKIKLSKFNSVQ 403
I+ + +D+ VKC L + +N + + N N + N Q
Sbjct: 279 IVILSKQVEDLN------------VKCQLLEKEKEDHVNRNREHNEN---LNAEMQNLKQ 323
Query: 404 HNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEV 463
L+ Q KL L++ + Q L + LH + + Q+E +KE N E
Sbjct: 324 KFILEQQEREKL-------QQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEE 376
Query: 464 KINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENS 523
++ E++K ++ + L +++ ++K + K E++LE S
Sbjct: 377 ELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGK------EAELEKS 430
Query: 524 PVENVTAASTLLSQAKIDTGENKFPGSAPQ-----------------QHSILSNQTSKSS 566
+ A TLL Q K D+ Q ++S L + +K+
Sbjct: 431 SAAHTQA--TLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAG 488
Query: 567 DNRETPRNHSLPKCNSHLE-ITIPKDLKLKEA-EKTDEKQLIIDAGQK 612
N E ++ L +S+ E + + DL+ K A ++T+ K++ + QK
Sbjct: 489 KNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQK 536
Score = 49.7 bits (117), Expect = 1e-05
Identities = 107/535 (20%), Positives = 208/535 (38%), Gaps = 91/535 (17%)
Query: 2 MSIQEKSKENSSKVTKKSDDK--NSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQ 59
+ + ++S E S + + K + E E D + K E I + + K++
Sbjct: 195 LQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDI 254
Query: 60 PELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQE-STKKKLSQKKL---VHENPKAN 115
+LE + ++ + S +S+ +N V + ++ + K +L +K+ V+ N + N
Sbjct: 255 AQLEENLKEKNDEILS---LKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHN 311
Query: 116 EQLNRRSQRLQQ---LTEVSRRSLRSREIQ--GQVQAVKQSLPPTKKEQCS--------- 161
E LN Q L+Q L + R L+ +E+Q +Q K+ ++ CS
Sbjct: 312 ENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEK 371
Query: 162 --------STQSKSNKTSQKHVKR----KVLEVKSDSKEDENLVINEVINSPKGKKRKVE 209
T + +K QK + K LE ++ S+ +E ++ E + KGK+ ++E
Sbjct: 372 NLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL---KGKEAELE 428
Query: 210 -----HQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKK----- 259
H A + + + T + E+ SE++ K+ S + +K
Sbjct: 429 KSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAG 488
Query: 260 ----------------NEMKKSVHTQVNTNTTLPKSPQPSVPE---QSDNELEQAGKSKR 300
N+ + + T + L ++ + Q +L+ K +
Sbjct: 489 KNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQE 548
Query: 301 GSILQLCEEIAG---EIESDNVEVKKESSQMESVKEE-----KPTEIKLEETSVERQILH 352
+ E+ G E E+ E+ +E ++ + EE KP +++L+ VE+Q L
Sbjct: 549 EDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALL 608
Query: 353 QKETNQDVQCNRFFPS-----------RKTKPVKCILNGINSSAKKNSNWTKIKLSKFNS 401
+ Q N+ S +K K V L NS K + + +L+K
Sbjct: 609 NEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHV-VKLKDENSQLKSEVSKLRCQLAK-KK 666
Query: 402 VQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMK 456
KL +++ LG+ P+ HH ++ L T L + N C + M+
Sbjct: 667 QSETKLQEELNKVLGI---KHFDPSKAFHHESKENFALKTPLKEGNTNCYRAPME 718
Score = 39.3 bits (90), Expect = 0.015
Identities = 61/334 (18%), Positives = 131/334 (39%), Gaps = 20/334 (5%)
Query: 35 LAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYS 94
+AK+ G + ++ +S ES+ +LE ++ + + T+ + + + S
Sbjct: 185 MAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCAS 244
Query: 95 QESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQ-VQAVKQSLP 153
+ K KL +L + N+++ Q L++ + + + ++ Q ++ K+
Sbjct: 245 DQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHV 304
Query: 154 PTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTA 213
+E + ++ QK + + K KE L I+ ++ K + HQ
Sbjct: 305 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKE---LQIDSLLQQEKELSSSL-HQKL 360
Query: 214 CACSSQCTQGSEKCPQKTTRRDETKPV--PVTSEVKRSKMATSVVPKKNEMKKSVHTQVN 271
C+ E +K +E K + ++ + A +V + E KS ++
Sbjct: 361 CSFQ------EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELK 414
Query: 272 TNTTLPKSPQPSVPEQSDNELEQAG---KSKRGSILQLCEEIAGEIESDNVEVKKESSQM 328
K + + E+S QA + K S++Q E++ + ES E +
Sbjct: 415 LLEEKLKGKEAEL-EKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDL 473
Query: 329 E---SVKEEKPTEIKLEETSVERQILHQKETNQD 359
+ S +EK + V+ QIL + +NQ+
Sbjct: 474 KLENSSLQEKAAKAGKNAEDVQHQILATESSNQE 507
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 50.8 bits (120), Expect = 5e-06
Identities = 45/193 (23%), Positives = 87/193 (45%), Gaps = 10/193 (5%)
Query: 1 MMSIQEKSKENSSKVTKKSDDK-----NSETEIQDSQKNLAKKSGPKETIKSQAKSSSES 55
+ +EK EN K +K +K S ++ + +K KKSG + S + SS S
Sbjct: 48 LAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSS 107
Query: 56 KINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKAN 115
+ + + + R K +++ KS + S++S KKK K E K
Sbjct: 108 SSDSEDEDKKQGKRRKK--KKNRSHKSSESSMSETESDSKDSLKKKKKSKDGT-EKEKDI 164
Query: 116 EQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHV 175
+ L+++ + + +S SL E +V+A K+ +++ + ++ ++K K +KH
Sbjct: 165 KGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKK--SSEEREKATEKTKKKKKHKKHS 222
Query: 176 KRKVLEVKSDSKE 188
K+K + S S +
Sbjct: 223 KKKKKKAASSSPD 235
Score = 34.3 bits (77), Expect = 0.49
Identities = 44/215 (20%), Positives = 80/215 (37%), Gaps = 18/215 (8%)
Query: 83 INKNTVTVRGYSQESTKKKLSQKKLVHENPKANE----QLNRRSQRLQQLTEVSRRSLRS 138
+N+ T ++ KKK K L K NE +L + ++L +E S + R
Sbjct: 24 LNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKK-RQ 82
Query: 139 REIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVI 198
R+ + + ++ + S + SS+ S S +K KR+ + K E+ +
Sbjct: 83 RKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETES 142
Query: 199 NSPKGKKRKVEHQTAC-------ACSSQCTQGSEKCPQKTTRRDETKPVPVT------SE 245
+S K+K + + S + SE P + E++ + S
Sbjct: 143 DSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSS 202
Query: 246 VKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSP 280
+R K KK K S + ++ P SP
Sbjct: 203 EEREKATEKTKKKKKHKKHSKKKKKKAASSSPDSP 237
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 50.8 bits (120), Expect = 5e-06
Identities = 45/193 (23%), Positives = 87/193 (45%), Gaps = 10/193 (5%)
Query: 1 MMSIQEKSKENSSKVTKKSDDK-----NSETEIQDSQKNLAKKSGPKETIKSQAKSSSES 55
+ +EK EN K +K +K S ++ + +K KKSG + S + SS S
Sbjct: 58 LAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSS 117
Query: 56 KINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKAN 115
+ + + + R K +++ KS + S++S KKK K E K
Sbjct: 118 SSDSEDEDKKQGKRRKK--KKNRSHKSSESSMSETESDSKDSLKKKKKSKDGT-EKEKDI 174
Query: 116 EQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHV 175
+ L+++ + + +S SL E +V+A K+ +++ + ++ ++K K +KH
Sbjct: 175 KGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKK--SSEEREKATEKTKKKKKHKKHS 232
Query: 176 KRKVLEVKSDSKE 188
K+K + S S +
Sbjct: 233 KKKKKKAASSSPD 245
Score = 34.3 bits (77), Expect = 0.49
Identities = 44/215 (20%), Positives = 80/215 (37%), Gaps = 18/215 (8%)
Query: 83 INKNTVTVRGYSQESTKKKLSQKKLVHENPKANE----QLNRRSQRLQQLTEVSRRSLRS 138
+N+ T ++ KKK K L K NE +L + ++L +E S + R
Sbjct: 34 LNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKK-RQ 92
Query: 139 REIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVI 198
R+ + + ++ + S + SS+ S S +K KR+ + K E+ +
Sbjct: 93 RKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETES 152
Query: 199 NSPKGKKRKVEHQTAC-------ACSSQCTQGSEKCPQKTTRRDETKPVPVT------SE 245
+S K+K + + S + SE P + E++ + S
Sbjct: 153 DSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSS 212
Query: 246 VKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSP 280
+R K KK K S + ++ P SP
Sbjct: 213 EEREKATEKTKKKKKHKKHSKKKKKKAASSSPDSP 247
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 50.1 bits (118), Expect = 9e-06
Identities = 77/375 (20%), Positives = 139/375 (37%), Gaps = 45/375 (12%)
Query: 3 SIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPEL 62
S E E+ K ++D N EI QK + + ++ +++ K +
Sbjct: 616 SSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKK----------QY 665
Query: 63 ETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRS 122
E ++ K + +N +V YS+E KK S E K + +N+
Sbjct: 666 EEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRS------EYEKKLQAMNKEL 719
Query: 123 QRLQQLTEVSRRSLRSR-EIQGQVQAVKQSLPPTKK------EQCSSTQSKSNKTSQKHV 175
QRLQ + R L+++ + + Q++ ++Q + KK +Q Q K+ T +
Sbjct: 720 QRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRR- 778
Query: 176 KRKVLEVKSDS-KEDENLVINEV--INSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTT 232
R++ ++K D K D L + E N +RK E T A Q S+K K T
Sbjct: 779 NREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVT--ALRRQVRPMSDKVAGKVT 836
Query: 233 RRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNEL 292
R+ + P + S A + ++ + V LP P + N
Sbjct: 837 RKLSSSDAP-AQDTGSSAAAVETDASRTGAQQKMRIPVARVQALP------TPATNGNRK 889
Query: 293 EQAGKSKRGSIL---------QLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEE 343
+ K G + QL E +I + + + M + +++ K E
Sbjct: 890 KYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRRE 949
Query: 344 TSVERQILHQKETNQ 358
+R+ KE +
Sbjct: 950 KLSKRREKIVKENGE 964
Score = 37.4 bits (85), Expect = 0.058
Identities = 61/302 (20%), Positives = 122/302 (40%), Gaps = 18/302 (5%)
Query: 40 GPKETIKSQAKSSSE----SKINQPELETRMSTRSSKAASN-DKATKSINKNTVTVRGYS 94
G +TI S S+ +N + R +K N D+A++ IN +
Sbjct: 338 GNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQ 397
Query: 95 QESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPP 154
E + K ++ + E ++ + + LQ TE + +R + +Q V A++ +
Sbjct: 398 MELMEYKTGKRIIDEEGVESINDMFHENAMLQ--TENNNLRVRIKAMQETVDALRSRITQ 455
Query: 155 TKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTAC 214
+Q + +++ + +++ +K L+ +E +N + ++ + TA
Sbjct: 456 LVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVN--ENLRKNLTRATAR 513
Query: 215 ACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVH-TQVNTN 273
A + S P + ET + ++ K+ K+ KKSV + NT+
Sbjct: 514 A--PYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKR----KEKRKKKSVAGKEDNTD 567
Query: 274 TTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKE 333
T K + V E+ +NELE + EE E E D+++ + S + +S +
Sbjct: 568 TDQEKKEEKGVSERENNELEVEESQEVSD--HEDEEEEEEEEEDDIDGGESSDESDSESD 625
Query: 334 EK 335
EK
Sbjct: 626 EK 627
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.124 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,436,304
Number of Sequences: 37866
Number of extensions: 1412243
Number of successful extensions: 7875
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 723
Number of HSP's that attempted gapping in prelim test: 6094
Number of HSP's gapped (non-prelim): 2171
length of query: 840
length of database: 18,247,518
effective HSP length: 111
effective length of query: 729
effective length of database: 14,044,392
effective search space: 10238361768
effective search space used: 10238361768
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.