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Search of human proteins with 239741053
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239741053 PREDICTED: similar to Putative PRAME family member
24 [Homo sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 956 0.0
gi|59676587 PRAME family member 8 [Homo sapiens] 955 0.0
gi|59676593 PRAME family member 7 [Homo sapiens] 954 0.0
gi|124249372 PRAME family member 12 [Homo sapiens] 802 0.0
gi|61696142 PRAME family member 5 [Homo sapiens] 585 e-167
gi|58219004 PRAME family member 6 [Homo sapiens] 585 e-167
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 580 e-166
gi|148356236 PRAME family member 15 [Homo sapiens] 575 e-164
gi|61102721 PRAME family member 9 [Homo sapiens] 575 e-164
gi|153792112 PRAME family member 20 [Homo sapiens] 566 e-161
gi|153945800 PRAME family member 21 [Homo sapiens] 566 e-161
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 565 e-161
gi|59958373 PRAME family member 4 [Homo sapiens] 564 e-161
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 523 e-148
gi|226437621 PRAME family member 11 [Homo sapiens] 507 e-143
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 454 e-128
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 454 e-128
gi|46249369 preferentially expressed antigen in melanoma [Homo s... 454 e-128
gi|46249367 preferentially expressed antigen in melanoma [Homo s... 454 e-128
gi|5174641 preferentially expressed antigen in melanoma [Homo sa... 454 e-128
gi|12738831 PRAME family member 1 [Homo sapiens] 450 e-126
gi|153791443 PRAME family member 18 [Homo sapiens] 448 e-126
gi|66954681 PRAME family member 13 [Homo sapiens] 448 e-126
gi|194018546 PRAME family member 10 [Homo sapiens] 446 e-125
gi|194306635 PRAME family member 19 [Homo sapiens] 445 e-125
gi|154800493 PRAME family member 22 [Homo sapiens] 441 e-124
gi|194306638 PRAME family member 3 [Homo sapiens] 441 e-124
gi|157426839 PRAME family member 17 [Homo sapiens] 440 e-123
gi|113865933 PRAME family member 16 [Homo sapiens] 438 e-123
gi|12738834 PRAME family member 2 [Homo sapiens] 437 e-122
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 956 bits (2472), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC 180
ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC
Sbjct: 121 ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC 180
Query: 181 KELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI 240
KELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI
Sbjct: 181 KELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI 240
Query: 241 RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT 300
RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT
Sbjct: 241 RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT 300
Query: 301 DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI 360
DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI
Sbjct: 301 DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI 360
Query: 361 MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT 420
MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT
Sbjct: 361 MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT 420
Query: 421 QGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
QGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC
Sbjct: 421 QGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 955 bits (2468), Expect = 0.0
Identities = 473/474 (99%), Positives = 474/474 (100%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC 180
ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC
Sbjct: 121 ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC 180
Query: 181 KELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI 240
+ELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI
Sbjct: 181 QELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI 240
Query: 241 RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT 300
RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT
Sbjct: 241 RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT 300
Query: 301 DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI 360
DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI
Sbjct: 301 DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI 360
Query: 361 MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT 420
MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT
Sbjct: 361 MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT 420
Query: 421 QGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
QGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC
Sbjct: 421 QGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 954 bits (2465), Expect = 0.0
Identities = 473/474 (99%), Positives = 473/474 (99%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC 180
ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC
Sbjct: 121 ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC 180
Query: 181 KELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI 240
KELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI
Sbjct: 181 KELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI 240
Query: 241 RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT 300
RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT
Sbjct: 241 RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT 300
Query: 301 DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI 360
DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI
Sbjct: 301 DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI 360
Query: 361 MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT 420
MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT
Sbjct: 361 MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT 420
Query: 421 QGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
QGALCWGRFAELGAELMKT RDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC
Sbjct: 421 QGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 802 bits (2071), Expect = 0.0
Identities = 397/473 (83%), Positives = 426/473 (90%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MS++APPRLLELA Q LLRD+ALAI T+EELPRELFP LFMEAF+RR CETL TMVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
FT LPLGSLMKS +LE ++VLEG+D LL Q+VRPR+ KLQVLDLRNVDENF I+SGA+
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCC 180
A PEALS+++TA NCP G QQP MV +DLC KN LDECLTH LEWGKQRKGLLHVCC
Sbjct: 121 ALSPEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHVCC 180
Query: 181 KELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNI 240
KELQ+FG+ IH IIEVLN VELDCIQEVEVCCPWELS L++FAPYLGQMRNLRKLVLFNI
Sbjct: 181 KELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLFNI 240
Query: 241 RASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMT 300
SACIP D K QF+ +FTSQFLKLDYFQ L MHSVSFLEGHLDQLLRCLQA LE VVMT
Sbjct: 241 HVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVVMT 300
Query: 301 DCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGI 360
+CLLSESDLKHLSWCPSIRQLKELDLRG+TLTHFSPEPL+ LLEQ ATLQTLDLEDCGI
Sbjct: 301 ECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDCGI 360
Query: 361 MDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDT 420
+DSQLSAILP LSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYD
Sbjct: 361 VDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDA 420
Query: 421 QGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
QGALCWGRF++LGAELMKTLRDLRQPKIIVF TVPCPRCGIRASYDLEPSHCL
Sbjct: 421 QGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCL 473
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 585 bits (1509), Expect = e-167
Identities = 300/476 (63%), Positives = 360/476 (75%), Gaps = 2/476 (0%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSIR PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F RLPL L+K P LE+ ++VL+G+D LLTQ V PR+ KLQVLDL++V ENF ++S A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A F A K+ +CP QQP VF++L LKNRTLDE LT LL W KQRK LLH+
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
CCK+L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG MRNL+KLVL
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
++ S + P+ K + + +FT+QFLKL Q LSM+SVSFLEGHLDQLL CL+ SL+++
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILP LSRC +L+TFSFCGN ISMA LENLL HT+ L L +ELYPAP ESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
D G LCW RFA++ AELMK +RDLR PK I+FCT CP CG R+ YDLE C C
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 585 bits (1507), Expect = e-167
Identities = 300/476 (63%), Positives = 359/476 (75%), Gaps = 2/476 (0%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSIR PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F RLPL L+K P LE+ ++VL+G+D LLTQ V PR+ KLQVLDL++V ENF ++S A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A F A K +CP QQP VF++L LKNRTLDE LT LL W KQRK LLH+
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
CCK+L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG MRNL+KLVL
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
++ S + P+ K + + +FT+QFLKL Q LSM+SVSFLEGHLDQLL CL+ SL+++
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILP LSRC +L+TFSFCGN ISMA LENLL HT+ L L +ELYPAP ESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
D G LCW RFA++ AELMK +RDLR PK I+FCT CP CG R+ YDLE C C
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 580 bits (1496), Expect = e-166
Identities = 298/476 (62%), Positives = 358/476 (75%), Gaps = 2/476 (0%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSIR PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F RLPL L+K P LE+ ++VL+G+D LLTQ V PR+ KLQVLDL++V ENF ++S A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A F A K+ +CP QQP VF++L LKNRTLDE LT LL W KQRK LLH+
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
CCK+L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG MRNL+KLVL
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
++ S + P+ K + + +FT+QFLKL Q LSM+SVSFLEGHLDQLL CL+ SL+++
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILP LS C +L+TFSFCGN ISMA LENLL HT+ L L +ELYPAP ESY
Sbjct: 361 GIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
D G LCW RF ++ AELMK +RDLR PK I+FCT CP CG R+ YDLE C C
Sbjct: 421 DADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 575 bits (1482), Expect = e-164
Identities = 295/476 (61%), Positives = 357/476 (75%), Gaps = 2/476 (0%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSIR PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F RLPL L+K P LE+ ++VL+G+D LLTQ VRPR+ KLQVLDL++V ENF ++S A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A F A K+ +CP +QP VF++L LKNRTLDE LT+LL W KQRK LLH+
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
CCK+L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG MRNL+KLVL
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
++ S + P+ K + + +FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+++
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
Query: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L L +ELYPAP ESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
G LCW RFA++ AELM +RDLR PK I+FCT CP CG R+ YDLE C
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 575 bits (1482), Expect = e-164
Identities = 295/476 (61%), Positives = 357/476 (75%), Gaps = 2/476 (0%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSIR PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F RLPL L+K P LE+ ++VL+G+D LLTQ VRPR+ KLQVLDL++V ENF ++S A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A F A K+ +CP +QP VF++L LKNRTLDE LT+LL W KQRK LLH+
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
CCK+L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG MRNL+KLVL
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
++ S + P+ K + + +FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+++
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
Query: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L L +ELYPAP ESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
G LCW RFA++ AELM +RDLR PK I+FCT CP CG R+ YDLE C
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 566 bits (1459), Expect = e-161
Identities = 296/476 (62%), Positives = 356/476 (74%), Gaps = 3/476 (0%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSIR PPRLLELA + LLRD+ALAIST+EELP ELFP LFMEAFSRR CE LK MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F RLPLGSLMK P E+ ++VL+G+D LLT VR R+ KLQVLDL++V ENF ++S A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A P A+ ++ +CP QQP VFIDLCLKNRTLDE T L W KQR+GL+H+
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
CCK+L++ GM H+I +L V LDCIQEVEV C W L L +F PYLGQMRNLRKLVL
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
+I S I P+ K +F+ +FT+QFLKL Q L M+SVSFLEGHLDQ+L CL+ SL ++
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
+T+C+L ESDLKHLS PSI QLK LDL G L +FS PL LLE+V ATL+ LDL+DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILP LSRC +L+TFSF GN IS A LENLL HT+ L+ L LELYPAP ESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
D +G +C RFA+LGAELM +R LR+P+ I+FCT CP+CG R+ YDLE C C
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 566 bits (1459), Expect = e-161
Identities = 296/476 (62%), Positives = 356/476 (74%), Gaps = 3/476 (0%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSIR PPRLLELA + LLRD+ALAIST+EELP ELFP LFMEAFSRR CE LK MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F RLPLGSLMK P E+ ++VL+G+D LLT VR R+ KLQVLDL++V ENF ++S A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A P A+ ++ +CP QQP VFIDLCLKNRTLDE T L W KQR+GL+H+
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
CCK+L++ GM H+I +L V LDCIQEVEV C W L L +F PYLGQMRNLRKLVL
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
+I S I P+ K +F+ +FT+QFLKL Q L M+SVSFLEGHLDQ+L CL+ SL ++
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
+T+C+L ESDLKHLS PSI QLK LDL G L +FS PL LLE+V ATL+ LDL+DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILP LSRC +L+TFSF GN IS A LENLL HT+ L+ L LELYPAP ESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
D +G +C RFA+LGAELM +R LR+P+ I+FCT CP+CG R+ YDLE C C
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 565 bits (1456), Expect = e-161
Identities = 292/476 (61%), Positives = 353/476 (74%), Gaps = 2/476 (0%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSIR PPRLLEL + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F RLPL L+K P LE+ ++VL+G+D LLTQ VRPR+ KLQVLDL++V ENF ++S A
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A F A K +CP +QP VF++L LKNRTLDE LT LL W KQR+ LLH+
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
CCK+L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG +RNL+KLVL
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
Query: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
++ S + P+ K + + +FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+++
Sbjct: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
Query: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
Query: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L L LELYPAP ESY
Sbjct: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
Query: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
G LCW RFA++ AELMK +R LR PK I+FCT CP G R+ YDLE C
Sbjct: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 564 bits (1454), Expect = e-161
Identities = 290/476 (60%), Positives = 353/476 (74%), Gaps = 2/476 (0%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSI PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F RLPL L+K P LE+ ++VL+G+D LL VRPR+ KLQVLDL++V ENF ++S A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A F A K+ ++CP +QP VF++L LKNRTLDE LT LL W KQRK LLH+
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
CCK+L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG MRNL+KL+L
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
Query: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
++ S + P+ K + + +FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+ +
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
Query: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L L +ELYPAP ESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
G LCW RFA++ AELM +RDLR PK I+FCT CP CG R+ YDLE C
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 523 bits (1347), Expect = e-148
Identities = 278/479 (58%), Positives = 350/479 (73%), Gaps = 10/479 (2%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL+LR+VDENF I+SGA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
+ PEA+S++QT ++CP TG +QP VF+D+CLK + +DE L+ W + R+G +H+
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
CC ++ + M I + +L V D IQ +E+ C P +V+F+PYL QMRNLRKL
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSPYLSQMRNLRKL 237
Query: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295
+ + + D++ Q IA FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+
Sbjct: 238 FISD-GCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLK 295
Query: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355
++ +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL
Sbjct: 296 VLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDL 355
Query: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
+DCGI+DSQ++AILP LSRC +L+TFSFCGN ISMA LENLL HT+ L L LELYPAP
Sbjct: 356 DDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPR 415
Query: 416 ESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
ESY G LCW RF ++ AELMK +RDLR PK I+F T CP CG R+ YDLE C
Sbjct: 416 ESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
>gi|226437621 PRAME family member 11 [Homo sapiens]
Length = 436
Score = 507 bits (1305), Expect = e-143
Identities = 261/436 (59%), Positives = 319/436 (73%), Gaps = 2/436 (0%)
Query: 41 MEAFSRRRCETLKTMVQAWPFTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKL 100
MEAFSRRRCE LK MVQAWPF RLPL L+K P LE+ ++VL+G+D LLTQ VRPR+ KL
Sbjct: 1 MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
Query: 101 QVLDLRNVDENFCDIFSGATAS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTL 158
QVLDL++V ENF ++S A A F A K +CP +QP VF++L LKNRTL
Sbjct: 61 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
Query: 159 DECLTHLLEWGKQRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELST 218
DE LT LL W KQR+ LLH+CCK+L++ GMP +I +L MV LDCIQEVEV C W L
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
Query: 219 LVKFAPYLGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSF 278
L +F PYLG +RNL+KLVL ++ S + P+ K + + +FT+QFLKL Q L M+SVSF
Sbjct: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
Query: 279 LEGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEP 338
LEGHLDQLL CL+ SL+++ +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S P
Sbjct: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
Query: 339 LTGLLEQVVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLR 398
L LLE+V ATL+ LDL+DCGI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL
Sbjct: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
Query: 399 HTVGLSKLSLELYPAPLESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPR 458
HT+ L L LELYPAP ESY G LCW RFA++ AELMK +R LR PK I+FCT CP
Sbjct: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
Query: 459 CGIRASYDLEPSHCLC 474
G R+ YDLE C
Sbjct: 421 HGDRSFYDLEADQYCC 436
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 454 bits (1168), Expect = e-128
Identities = 255/485 (52%), Positives = 329/485 (67%), Gaps = 16/485 (3%)
Query: 5 APPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRL 64
+P RL+ELA Q LL+D+ALAI+ +E LPRELFP LFM AF R +TLK MVQAWPFT L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKSPHL--ESLKSVLEGVDVLLTQEVRPRQSKLQVLDLR-NVDENFCDIFSGATA 121
PLG LMK HL E+ K+VL+G+DVLL QEVRPR+ KLQVLDLR N ++F ++SG A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 S---FPEA-----LSQKQTADNCPGTGRQQPFM---VFIDLCLKNRTLDECLTHLLEWGK 170
S FPE +++K+ D T +QPF+ V +DL LK DE ++L+E K
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGL-STEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVK 200
Query: 171 QRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMR 230
++K +L +CCK+L++F MP+ I +L MV+LD I+++EV C W+L TL KF+PYLGQM
Sbjct: 201 RKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMI 260
Query: 231 NLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCL 290
NLR+L+L +I AS+ I P+ + Q+IA+FTSQFL L Q L + S+ FL G LDQLLR +
Sbjct: 261 NLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 291 QASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATL 350
LE + +T+C LSE D+ HLS PS+ QL L L GV LT SPEPL LLE+ ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 351 QTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLEL 410
Q L ++CGI D QL A+LP LS CSQL+T SF GN IS++AL++LL+H +GLS L+ L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 411 YPAPLESY-DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEP 469
YP PLESY D G L R A L A L + L +L +P ++ PCP CG R YD EP
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
Query: 470 SHCLC 474
C C
Sbjct: 501 ILCPC 505
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 454 bits (1168), Expect = e-128
Identities = 255/485 (52%), Positives = 329/485 (67%), Gaps = 16/485 (3%)
Query: 5 APPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRL 64
+P RL+ELA Q LL+D+ALAI+ +E LPRELFP LFM AF R +TLK MVQAWPFT L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKSPHL--ESLKSVLEGVDVLLTQEVRPRQSKLQVLDLR-NVDENFCDIFSGATA 121
PLG LMK HL E+ K+VL+G+DVLL QEVRPR+ KLQVLDLR N ++F ++SG A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 S---FPEA-----LSQKQTADNCPGTGRQQPFM---VFIDLCLKNRTLDECLTHLLEWGK 170
S FPE +++K+ D T +QPF+ V +DL LK DE ++L+E K
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGL-STEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVK 200
Query: 171 QRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMR 230
++K +L +CCK+L++F MP+ I +L MV+LD I+++EV C W+L TL KF+PYLGQM
Sbjct: 201 RKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMI 260
Query: 231 NLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCL 290
NLR+L+L +I AS+ I P+ + Q+IA+FTSQFL L Q L + S+ FL G LDQLLR +
Sbjct: 261 NLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 291 QASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATL 350
LE + +T+C LSE D+ HLS PS+ QL L L GV LT SPEPL LLE+ ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 351 QTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLEL 410
Q L ++CGI D QL A+LP LS CSQL+T SF GN IS++AL++LL+H +GLS L+ L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 411 YPAPLESY-DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEP 469
YP PLESY D G L R A L A L + L +L +P ++ PCP CG R YD EP
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
Query: 470 SHCLC 474
C C
Sbjct: 501 ILCPC 505
>gi|46249369 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 454 bits (1168), Expect = e-128
Identities = 255/485 (52%), Positives = 329/485 (67%), Gaps = 16/485 (3%)
Query: 5 APPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRL 64
+P RL+ELA Q LL+D+ALAI+ +E LPRELFP LFM AF R +TLK MVQAWPFT L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKSPHL--ESLKSVLEGVDVLLTQEVRPRQSKLQVLDLR-NVDENFCDIFSGATA 121
PLG LMK HL E+ K+VL+G+DVLL QEVRPR+ KLQVLDLR N ++F ++SG A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 S---FPEA-----LSQKQTADNCPGTGRQQPFM---VFIDLCLKNRTLDECLTHLLEWGK 170
S FPE +++K+ D T +QPF+ V +DL LK DE ++L+E K
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGL-STEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVK 200
Query: 171 QRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMR 230
++K +L +CCK+L++F MP+ I +L MV+LD I+++EV C W+L TL KF+PYLGQM
Sbjct: 201 RKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMI 260
Query: 231 NLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCL 290
NLR+L+L +I AS+ I P+ + Q+IA+FTSQFL L Q L + S+ FL G LDQLLR +
Sbjct: 261 NLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 291 QASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATL 350
LE + +T+C LSE D+ HLS PS+ QL L L GV LT SPEPL LLE+ ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 351 QTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLEL 410
Q L ++CGI D QL A+LP LS CSQL+T SF GN IS++AL++LL+H +GLS L+ L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 411 YPAPLESY-DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEP 469
YP PLESY D G L R A L A L + L +L +P ++ PCP CG R YD EP
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
Query: 470 SHCLC 474
C C
Sbjct: 501 ILCPC 505
>gi|46249367 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 454 bits (1168), Expect = e-128
Identities = 255/485 (52%), Positives = 329/485 (67%), Gaps = 16/485 (3%)
Query: 5 APPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRL 64
+P RL+ELA Q LL+D+ALAI+ +E LPRELFP LFM AF R +TLK MVQAWPFT L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKSPHL--ESLKSVLEGVDVLLTQEVRPRQSKLQVLDLR-NVDENFCDIFSGATA 121
PLG LMK HL E+ K+VL+G+DVLL QEVRPR+ KLQVLDLR N ++F ++SG A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 S---FPEA-----LSQKQTADNCPGTGRQQPFM---VFIDLCLKNRTLDECLTHLLEWGK 170
S FPE +++K+ D T +QPF+ V +DL LK DE ++L+E K
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGL-STEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVK 200
Query: 171 QRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMR 230
++K +L +CCK+L++F MP+ I +L MV+LD I+++EV C W+L TL KF+PYLGQM
Sbjct: 201 RKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMI 260
Query: 231 NLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCL 290
NLR+L+L +I AS+ I P+ + Q+IA+FTSQFL L Q L + S+ FL G LDQLLR +
Sbjct: 261 NLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 291 QASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATL 350
LE + +T+C LSE D+ HLS PS+ QL L L GV LT SPEPL LLE+ ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 351 QTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLEL 410
Q L ++CGI D QL A+LP LS CSQL+T SF GN IS++AL++LL+H +GLS L+ L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 411 YPAPLESY-DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEP 469
YP PLESY D G L R A L A L + L +L +P ++ PCP CG R YD EP
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
Query: 470 SHCLC 474
C C
Sbjct: 501 ILCPC 505
>gi|5174641 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 454 bits (1168), Expect = e-128
Identities = 255/485 (52%), Positives = 329/485 (67%), Gaps = 16/485 (3%)
Query: 5 APPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRL 64
+P RL+ELA Q LL+D+ALAI+ +E LPRELFP LFM AF R +TLK MVQAWPFT L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKSPHL--ESLKSVLEGVDVLLTQEVRPRQSKLQVLDLR-NVDENFCDIFSGATA 121
PLG LMK HL E+ K+VL+G+DVLL QEVRPR+ KLQVLDLR N ++F ++SG A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 S---FPEA-----LSQKQTADNCPGTGRQQPFM---VFIDLCLKNRTLDECLTHLLEWGK 170
S FPE +++K+ D T +QPF+ V +DL LK DE ++L+E K
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGL-STEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVK 200
Query: 171 QRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMR 230
++K +L +CCK+L++F MP+ I +L MV+LD I+++EV C W+L TL KF+PYLGQM
Sbjct: 201 RKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMI 260
Query: 231 NLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCL 290
NLR+L+L +I AS+ I P+ + Q+IA+FTSQFL L Q L + S+ FL G LDQLLR +
Sbjct: 261 NLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 291 QASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATL 350
LE + +T+C LSE D+ HLS PS+ QL L L GV LT SPEPL LLE+ ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 351 QTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLEL 410
Q L ++CGI D QL A+LP LS CSQL+T SF GN IS++AL++LL+H +GLS L+ L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 411 YPAPLESY-DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEP 469
YP PLESY D G L R A L A L + L +L +P ++ PCP CG R YD EP
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
Query: 470 SHCLC 474
C C
Sbjct: 501 ILCPC 505
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 450 bits (1157), Expect = e-126
Identities = 258/478 (53%), Positives = 327/478 (68%), Gaps = 11/478 (2%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LFMEAFSRR +TL MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
FT LPLGSLMK+ HLE+LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A FPE S++QTA++CP G QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
CC +L + PI + + L ++ L+ IQE+E+ + K YL +M+NLRKLV
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVF- 239
Query: 239 NIRASAC--IPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294
S C DN+ G+ +A+F+S FL+L++ Q L + ++F GHL+QL+RCLQ L
Sbjct: 240 ----SRCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPL 295
Query: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354
E + +T L E D+K LS PS+ LK L+L V L S EPL LLE++ A+L+TL
Sbjct: 296 ENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLI 355
Query: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414
LE C I SQLSAILP LSRCSQL+TF F N +S+ AL++LLRHT GLSKLSLE YPAP
Sbjct: 356 LEGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAP 415
Query: 415 LESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHC 472
ES ++ + W F L AELM TLR++RQPK I PCP CG S +LE C
Sbjct: 416 EESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 448 bits (1153), Expect = e-126
Identities = 248/479 (51%), Positives = 326/479 (68%), Gaps = 11/479 (2%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MS +AP RLLELA Q LLRDQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL++R+VDENF I+SGA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
+ PEA+S++QT ++CP TG +QP VF+D+CLK +++DE L+ W + R+ +H+
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
CC ++ + M I + +L V D IQ +E+ C P ++ + + YL QM+NLRKL
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
Query: 236 VLFNIRASACIPP-DNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294
+ + +P +++GQ +A F+S FL+L+Y Q L M + F EG+LDQL+RCL++ L
Sbjct: 238 FISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPL 295
Query: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354
E + +T L E DLK L W PS+ QLK+L+L TL EPL LLE+V ATLQTL
Sbjct: 296 ETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLF 355
Query: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414
L DCGI DS+L ILP LSRCS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 356 LVDCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 415
Query: 415 LESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
ES D +G + L AELM+ LR++R+P I F V CP CG+ + LE + CL
Sbjct: 416 RESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCL 474
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 448 bits (1153), Expect = e-126
Identities = 255/476 (53%), Positives = 325/476 (68%), Gaps = 7/476 (1%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LFMEAF RR +TL MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
FT LPLGSLMK+ HLE+LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A FPE +S++QTA++CP G QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
CC +L + PI + + L ++ L+ IQ++E+ + K YL +M+NLRKLV
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 239 NIRASACIPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEM 296
S DN+ G+ + +F+S FL+L++ Q L + ++F GHL+QL+RCLQ LE
Sbjct: 241 RCHHSMS---DNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
Query: 297 VVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLE 356
+ +T L E D+K LS PS+ LK L+L V L S EPL LLE++ A+L+TL LE
Sbjct: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILE 357
Query: 357 DCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLE 416
C I SQLSAILP LS CSQL+TF F N +SM AL++LLRHT GLSKLSLE YPAP E
Sbjct: 358 GCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEE 417
Query: 417 SYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHC 472
S ++ + W FA L AELM TLR++RQPK I PCP CG S +LE C
Sbjct: 418 SLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 446 bits (1146), Expect = e-125
Identities = 248/463 (53%), Positives = 315/463 (68%), Gaps = 5/463 (1%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MS++AP RLLELA Q LLR+Q L I T++ELPRE+FP +FMEAFS RR E LK MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F LPLGSLMK+ HLE+L++VL G+D L+ Q+VRPR+ KLQVLDLR+VDENF I+SGA
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
+ PEA+S++QT ++CP G QP VFIDLCLK TLDECL++L W R+GL+H+
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237
CC ++Q + MP S +L + D IQE+EV L+ KFAPYL QM NLR+L L
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297
F + + I S FL L Y Q L + +S ++ HL+ LLR L+ L
Sbjct: 241 FGYERELYVSV--QWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
Query: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357
+ +D L++ D++ LS PS+ QLKEL L + + EPL LLE+V ATL+TL L+D
Sbjct: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
Query: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417
C I D QL +LP LS CSQL+TF+F GN SM AL++LLRHT GLSKL LELYPAPLES
Sbjct: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
Query: 418 YDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCG 460
D +G + W + AELM+TLR++RQPK I F VPCP CG
Sbjct: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 445 bits (1144), Expect = e-125
Identities = 247/479 (51%), Positives = 325/479 (67%), Gaps = 11/479 (2%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MS +AP RLLELA Q LLRDQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL++R+VDENF I+SGA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
+ PEA+S++QT ++CP TG +QP VF+D+CLK +++DE L+ W + R+ +H+
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
CC ++ + M I + +L V D IQ +E+ C P ++ + + YL QM+NLRKL
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
Query: 236 VLFNIRASACIPP-DNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294
+ + +P +++GQ +A F+S FL+L+Y Q L M + F EG+LDQL+RCL++ L
Sbjct: 238 FISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPL 295
Query: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354
E + +T L E DLK L W PS+ QLK+L+L TL EPL LLE+V ATLQTL
Sbjct: 296 ETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLF 355
Query: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414
L DCGI S+L ILP LSRCS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 356 LVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 415
Query: 415 LESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
ES D +G + L AELM+ LR++R+P I F V CP CG+ + LE + CL
Sbjct: 416 RESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCL 474
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 441 bits (1134), Expect = e-124
Identities = 247/478 (51%), Positives = 320/478 (66%), Gaps = 9/478 (1%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL+LR+VDENF I+SGA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
+ PEA+S++QT ++CP TG +QP VF+D+CLK + +DE L+ W + R+G +H+
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
CC ++ + M I + +L V D IQ +E+ C P +V+F+ YL QMRNLRKL
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSRYLSQMRNLRKL 239
Query: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295
+ + + D++ Q +A F+S L+L+Y Q L + V F GHLDQL+RCL++ LE
Sbjct: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
Query: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355
+ +T L + DLK L PS+ QLK+L+L L EPL LLE+V ATLQTL L
Sbjct: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
Query: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
DCGI DS+L ILP LS CS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
Query: 416 ESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
ES D +G + L AELM+ LR++R+PK I F V CP CG + LE + CL
Sbjct: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 441 bits (1134), Expect = e-124
Identities = 247/478 (51%), Positives = 319/478 (66%), Gaps = 9/478 (1%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL+LR+VDENF I+SGA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
+ PEA+S++QT ++CP TG +QP VF+D+CLK + +DE L+ W + R+G +H+
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
CC ++ + M I + +L V D IQ +E+ C P +V+F YL QMRNLRKL
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFIRYLSQMRNLRKL 239
Query: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295
+ + + D++ Q +A F+S L+L+Y Q L + V F GHLDQL+RCL++ LE
Sbjct: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
Query: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355
+ +T L + DLK L PS+ QLK+L+L L EPL LLE+V ATLQTL L
Sbjct: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
Query: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
DCGI DS+L ILP LS CS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
Query: 416 ESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
ES D +G + L AELM+ LR++R+PK I F V CP CG + LE + CL
Sbjct: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 440 bits (1132), Expect = e-123
Identities = 244/463 (52%), Positives = 311/463 (67%), Gaps = 5/463 (1%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MS+++P RLLELA Q LLR+Q L I ++ELPRE+FP +FMEA S R E LK MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F RLPLGSLMK+PHLE+L++VL+G+D LL Q++RPR+ KLQVLDLR+VD NF I+SGA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A PEA+S++QT ++ P TG QP VFIDLC K TLDECL++L W R+GL+H+
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237
CC ++Q + MP S +L V D IQE+E+ L+ KFAPYL QM NLRKL L
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297
F + + QF+ FL L Y Q L + +S ++ HL+ LLRCL+ L
Sbjct: 241 FGYDDELYV--SGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
Query: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357
+ L++ D++ LS PS+ QLKEL L + + + EPL LLE+V ATL+ L L+D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
Query: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417
C I DSQL +LP LSRCSQL+TF F GN S AL++LL HT GLSKL LELYPAPLE
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
Query: 418 YDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCG 460
D +G + W A + AELM TLR++RQPK I F +PCP CG
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 438 bits (1127), Expect = e-123
Identities = 243/463 (52%), Positives = 310/463 (66%), Gaps = 5/463 (1%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MS+++P RLLELA Q LLR+Q L I ++ELPRE+FP +FMEA S R E LK MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
F RLPLGSLMK+PHLE+L++VL+G+D LL Q++RPR+ KLQVLDLR+VD NF I+SGA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A PEA+ ++QT ++ P TG QP VFIDLC K TLDECL++L W R+GL+H+
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237
CC ++Q + MP S +L V D IQE+E+ L+ KFAPYL QM NLRKL L
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297
F + + QF+ FL L Y Q L + +S ++ HL+ LLRCL+ L
Sbjct: 241 FGYDDELYV--SGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
Query: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357
+ L++ D++ LS PS+ QLKEL L + + + EPL LLE+V ATL+ L L+D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
Query: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417
C I DSQL +LP LSRCSQL+TF F GN S AL++LL HT GLSKL LELYPAPLE
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
Query: 418 YDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCG 460
D +G + W A + AELM TLR++RQPK I F +PCP CG
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 437 bits (1123), Expect = e-122
Identities = 257/481 (53%), Positives = 322/481 (66%), Gaps = 17/481 (3%)
Query: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LF EAFSRR +TL MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
FT LPL SLMK+ HLE LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
A FPEA+S++QTA++CP TG QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
CC +L + PI + + L ++ ++ I E+E+ C P + K YL +M+ L KL
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWP---HLIRKLYCYLKEMKTLCKL 237
Query: 236 VLFNIRASAC--IPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQ 291
V S C DN+ G + RFTS FL+L++ Q L + ++F GHL+QL+RCLQ
Sbjct: 238 VF-----SRCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQ 292
Query: 292 ASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQ 351
LE + +T L E DLK LS PS+ LK L+L V L S EPL LLE++ A+L+
Sbjct: 293 NPLENLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLE 352
Query: 352 TLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELY 411
TL LE C I SQLSAILP LS CSQL+TF F N +S+ AL++LLRHT GLSKLSLE Y
Sbjct: 353 TLVLEGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETY 412
Query: 412 PAPLESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSH 471
PAP ES ++ + W F L AELM TLR+ RQPK I PCP CG S +LE
Sbjct: 413 PAPEESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHL 472
Query: 472 C 472
C
Sbjct: 473 C 473
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,329,510
Number of Sequences: 37866
Number of extensions: 728501
Number of successful extensions: 2278
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2132
Number of HSP's gapped (non-prelim): 75
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.