BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239740950 PREDICTED: similar to mitogen-activated protein kinase 8 interacting protein 1 [Homo sapiens] (442 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239740950 PREDICTED: similar to mitogen-activated protein kin... 909 0.0 gi|169211037 PREDICTED: similar to mitogen-activated protein kin... 837 0.0 gi|4885433 mitogen-activated protein kinase 8 interacting protei... 643 0.0 gi|6912492 mitogen-activated protein kinase 8 interacting protei... 352 5e-97 gi|7706537 mitogen-activated protein kinase 8 interacting protei... 352 5e-97 gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom... 61 2e-09 gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein i... 43 5e-04 gi|50511947 cajalin 2 isoform b [Homo sapiens] 42 9e-04 gi|50511945 cajalin 2 isoform a [Homo sapiens] 42 9e-04 gi|10047134 cajalin 2 isoform c [Homo sapiens] 42 9e-04 gi|140161500 ankyrin repeat and sterile alpha motif domain conta... 42 0.001 gi|194473700 Src homology 3 domain-containing guanine nucleotide... 40 0.004 gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens] 39 0.007 gi|10863899 numb homolog (Drosophila)-like [Homo sapiens] 39 0.009 gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens] 38 0.021 gi|90403598 mesoderm posterior 2 homolog [Homo sapiens] 37 0.027 gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens] 37 0.036 gi|54144629 numb homolog isoform 4 [Homo sapiens] 37 0.047 gi|20070356 numb homolog isoform 3 [Homo sapiens] 37 0.047 gi|50083291 amyloid beta A4 precursor protein-binding, family B,... 36 0.061 gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo ... 36 0.061 gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo s... 36 0.061 gi|18093112 ABT1-associated protein [Homo sapiens] 36 0.061 gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ... 35 0.10 gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ... 35 0.10 gi|54144627 numb homolog isoform 2 [Homo sapiens] 35 0.14 gi|54144625 numb homolog isoform 1 [Homo sapiens] 35 0.14 gi|49640014 ubiquitin associated and SH3 domain containing, A sh... 35 0.14 gi|9507221 ubiquitin associated and SH3 domain containing, A lon... 35 0.14 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 35 0.14 >gi|239740950 PREDICTED: similar to mitogen-activated protein kinase 8 interacting protein 1 [Homo sapiens] Length = 442 Score = 909 bits (2348), Expect = 0.0 Identities = 442/442 (100%), Positives = 442/442 (100%) Query: 1 MLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGP 60 MLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGP Sbjct: 1 MLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGP 60 Query: 61 GSGDTYRPKRPTTLNLFPQVQLSQDTLNNNSLGKKYKQPRPHHRSRHLHQQPTLLVDEHA 120 GSGDTYRPKRPTTLNLFPQVQLSQDTLNNNSLGKKYKQPRPHHRSRHLHQQPTLLVDEHA Sbjct: 61 GSGDTYRPKRPTTLNLFPQVQLSQDTLNNNSLGKKYKQPRPHHRSRHLHQQPTLLVDEHA 120 Query: 121 QLELVSLRPCFGDYSDESDSAIVYDNCVSVSSPYESAIGEEYEEASRPQPPACLSKDSTP 180 QLELVSLRPCFGDYSDESDSAIVYDNCVSVSSPYESAIGEEYEEASRPQPPACLSKDSTP Sbjct: 121 QLELVSLRPCFGDYSDESDSAIVYDNCVSVSSPYESAIGEEYEEASRPQPPACLSKDSTP 180 Query: 181 DEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHRTIFRFVPRHEDEPEL 240 DEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHRTIFRFVPRHEDEPEL Sbjct: 181 DEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHRTIFRFVPRHEDEPEL 240 Query: 241 EVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVTKEPEHMAALAKNSDWVDQFRV 300 EVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVTKEPEHMAALAKNSDWVDQFRV Sbjct: 241 EVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVTKEPEHMAALAKNSDWVDQFRV 300 Query: 301 KFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQE 360 KFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQE Sbjct: 301 KFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQE 360 Query: 361 AKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTKALAESVGR 420 AKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTKALAESVGR Sbjct: 361 AKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTKALAESVGR 420 Query: 421 AFQQFHKQFVEYTCPTEDIYLE 442 AFQQFHKQFVEYTCPTEDIYLE Sbjct: 421 AFQQFHKQFVEYTCPTEDIYLE 442 >gi|169211037 PREDICTED: similar to mitogen-activated protein kinase 8 interacting protein 1 [Homo sapiens] Length = 423 Score = 837 bits (2162), Expect = 0.0 Identities = 418/442 (94%), Positives = 420/442 (95%), Gaps = 19/442 (4%) Query: 1 MLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGP 60 MLQMDLIDATGDTPGAE EDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGP Sbjct: 1 MLQMDLIDATGDTPGAE---EDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGP 57 Query: 61 GSGDTYRPKRPTTLNLFPQVQLSQDTLNNNSLGKKYKQPRPHHRSRHLHQQPTLLVDEHA 120 GSGDTYRPKRPTTLNLFPQVQLSQDTLNNNSLGKK SRHLHQQPTLL Sbjct: 58 GSGDTYRPKRPTTLNLFPQVQLSQDTLNNNSLGKK---------SRHLHQQPTLL----- 103 Query: 121 QLELVSLRPCFGDYSDESDSAIVYDNCVSVSSPYESAIGEEYEEASRPQPPACLSKDSTP 180 ELVSLRPCF DYSDESDSAIVYDNC SVSSPYESAIGEEYEEASRPQPPACLSKDSTP Sbjct: 104 --ELVSLRPCFRDYSDESDSAIVYDNCASVSSPYESAIGEEYEEASRPQPPACLSKDSTP 161 Query: 181 DEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHRTIFRFVPRHEDEPEL 240 DEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHRTIFRFVPRHEDEPEL Sbjct: 162 DEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHRTIFRFVPRHEDEPEL 221 Query: 241 EVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVTKEPEHMAALAKNSDWVDQFRV 300 EVDDPLLVELQAEDYWYEAYNMRTGARG FTAYYAIEVTKEPEHMAALAKNSDWVDQFRV Sbjct: 222 EVDDPLLVELQAEDYWYEAYNMRTGARGIFTAYYAIEVTKEPEHMAALAKNSDWVDQFRV 281 Query: 301 KFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQE 360 KFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIG+KADDSQE Sbjct: 282 KFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGIKADDSQE 341 Query: 361 AKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTKALAESVGR 420 AKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTKALAESVGR Sbjct: 342 AKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTKALAESVGR 401 Query: 421 AFQQFHKQFVEYTCPTEDIYLE 442 AFQQFHKQFVEYTCPTE+IYLE Sbjct: 402 AFQQFHKQFVEYTCPTENIYLE 423 >gi|4885433 mitogen-activated protein kinase 8 interacting protein 1 [Homo sapiens] Length = 711 Score = 643 bits (1658), Expect = 0.0 Identities = 333/422 (78%), Positives = 345/422 (81%), Gaps = 25/422 (5%) Query: 24 DEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSG---DTYRPKRPTTLNLFPQV 80 D + AA AG P +E S +++ PG G P P P+ Sbjct: 312 DPDPAAYPSTAGRPHPSISEEEEGFDCLSSPERAEPPGGGWRGSLGEPPPP------PRA 365 Query: 81 QLSQDTLNNNSLGKKYKQPRPHHRSRHLHQQPTLLVDEHAQLELVSLRPCFGDYSDESDS 140 LS DT + KY TL+VDEHAQLELVSLRPCFGDYSDESDS Sbjct: 366 SLSSDTSALSYDSVKY----------------TLVVDEHAQLELVSLRPCFGDYSDESDS 409 Query: 141 AIVYDNCVSVSSPYESAIGEEYEEASRPQPPACLSKDSTPDEPDVHFSKKFLNIFMSGRS 200 A VYDNC SVSSPYESAIGEEYEEA RPQPPACLS+DSTPDEPDVHFSKKFLN+FMSGRS Sbjct: 410 ATVYDNCASVSSPYESAIGEEYEEAPRPQPPACLSEDSTPDEPDVHFSKKFLNVFMSGRS 469 Query: 201 RSSSAESFGLFSCIINREEQEQTHRTIFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAY 260 RSSSAESFGLFSCIIN EEQEQTHR IFRFVPRHEDE ELEVDDPLLVELQAEDYWYEAY Sbjct: 470 RSSSAESFGLFSCIINGEEQEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAY 529 Query: 261 NMRTGARGFFTAYYAIEVTKEPEHMAALAKNSDWVDQFRVKFLGSVQVPYHKGDVVLSAA 320 NMRTGARG F AYYAIEVTKEPEHMAALAKNSDWVDQFRVKFLGSVQVPYHKG+ VL AA Sbjct: 530 NMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWVDQFRVKFLGSVQVPYHKGNDVLCAA 589 Query: 321 MQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISFRGY 380 MQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISF GY Sbjct: 590 MQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISFCGY 649 Query: 381 HPKNNKYFGFITKHLADHRFACHVFVSEDSTKALAESVGRAFQQFHKQFVEYTCPTEDIY 440 HPKNNKYFGFITKH ADHRFACHVFVSEDSTKALAESVGRAFQQF+KQFVEYTCPTEDIY Sbjct: 650 HPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIY 709 Query: 441 LE 442 LE Sbjct: 710 LE 711 Score = 192 bits (489), Expect = 4e-49 Identities = 93/96 (96%), Positives = 94/96 (97%) Query: 1 MLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGP 60 MLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGP Sbjct: 91 MLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGP 150 Query: 61 GSGDTYRPKRPTTLNLFPQVQLSQDTLNNNSLGKKY 96 GSGDTYRPKRPTTLNLFPQV SQDTLNNNSLGKK+ Sbjct: 151 GSGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKH 186 >gi|6912492 mitogen-activated protein kinase 8 interacting protein 2 isoform 1 [Homo sapiens] Length = 824 Score = 352 bits (902), Expect = 5e-97 Identities = 179/337 (53%), Positives = 233/337 (69%), Gaps = 31/337 (9%) Query: 113 TLLVDEHAQLELVSLRPCFG-DYSDESDSAIVYDNCVSVSSPYESAIGEEYEEASRPQPP 171 TL+VDEH QLELVSLR C G + E DS EAS + Sbjct: 512 TLVVDEHTQLELVSLRRCAGLGHDSEEDSG---------------------GEASEEEAG 550 Query: 172 ACL------SKDSTPDEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHR 225 A L S D++PD PD+ FSKKFLN+F++ SRSSS ESFGLFSC++N EE+EQTHR Sbjct: 551 AALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHR 610 Query: 226 TIFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVTKEPEHM 285 +FRF+PRH DE EL+VDDP+LVE + +D+W+ +NMRTG RG F A+YA V + + Sbjct: 611 AVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDL 670 Query: 286 AALAKNSDWVDQFRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEIS 345 ++ WV++F V+FLGSV+VP H+G+ +L AAMQKIAT R+LTVH PP+SC LEIS Sbjct: 671 LGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEIS 730 Query: 346 VRGVKIGVKADDSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVF 405 +RGVK+ + + +CSHFFQ+KNISF G HP+N+ YFGFITKH RFACHVF Sbjct: 731 LRGVKLSLSGGGPE---FQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVF 787 Query: 406 VSEDSTKALAESVGRAFQQFHKQFVEYTCPTEDIYLE 442 VS++S + +A+SVGRAF +++++ + Y CPTEDIYLE Sbjct: 788 VSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 824 Score = 34.7 bits (78), Expect = 0.18 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 4/74 (5%) Query: 17 EDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNL 76 +++EEDD++E G + + G +P S + + G S + RPTTL L Sbjct: 86 DNEEEDDEDEEEEEEEEEGDGEGQEGGDPGS--EAPAPGPLIPSPSVEEPHKHRPTTLRL 143 Query: 77 FPQVQLSQDTLNNN 90 +QD+LNNN Sbjct: 144 --TTLGAQDSLNNN 155 >gi|7706537 mitogen-activated protein kinase 8 interacting protein 2 isoform 2 [Homo sapiens] Length = 797 Score = 352 bits (902), Expect = 5e-97 Identities = 179/337 (53%), Positives = 233/337 (69%), Gaps = 31/337 (9%) Query: 113 TLLVDEHAQLELVSLRPCFG-DYSDESDSAIVYDNCVSVSSPYESAIGEEYEEASRPQPP 171 TL+VDEH QLELVSLR C G + E DS EAS + Sbjct: 485 TLVVDEHTQLELVSLRRCAGLGHDSEEDSG---------------------GEASEEEAG 523 Query: 172 ACL------SKDSTPDEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHR 225 A L S D++PD PD+ FSKKFLN+F++ SRSSS ESFGLFSC++N EE+EQTHR Sbjct: 524 AALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHR 583 Query: 226 TIFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVTKEPEHM 285 +FRF+PRH DE EL+VDDP+LVE + +D+W+ +NMRTG RG F A+YA V + + Sbjct: 584 AVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDL 643 Query: 286 AALAKNSDWVDQFRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEIS 345 ++ WV++F V+FLGSV+VP H+G+ +L AAMQKIAT R+LTVH PP+SC LEIS Sbjct: 644 LGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEIS 703 Query: 346 VRGVKIGVKADDSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVF 405 +RGVK+ + + +CSHFFQ+KNISF G HP+N+ YFGFITKH RFACHVF Sbjct: 704 LRGVKLSLSGGGPE---FQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVF 760 Query: 406 VSEDSTKALAESVGRAFQQFHKQFVEYTCPTEDIYLE 442 VS++S + +A+SVGRAF +++++ + Y CPTEDIYLE Sbjct: 761 VSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 797 Score = 34.7 bits (78), Expect = 0.18 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 4/74 (5%) Query: 17 EDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNL 76 +++EEDD++E G + + G +P S + + G S + RPTTL L Sbjct: 59 DNEEEDDEDEEEEEEEEEGDGEGQEGGDPGS--EAPAPGPLIPSPSVEEPHKHRPTTLRL 116 Query: 77 FPQVQLSQDTLNNN 90 +QD+LNNN Sbjct: 117 --TTLGAQDSLNNN 128 >gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo sapiens] Length = 304 Score = 60.8 bits (146), Expect = 2e-09 Identities = 42/135 (31%), Positives = 66/135 (48%), Gaps = 8/135 (5%) Query: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCV-LEISVRGVKIGVKAD 356 + KFLGS +V KG V+ A++K+ R + V L+IS+ GVKI Sbjct: 27 YNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKI----- 81 Query: 357 DSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTKALAE 416 E K + H QL ISF + + F FI K ++ C+VF SE + + Sbjct: 82 --LEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITL 139 Query: 417 SVGRAFQQFHKQFVE 431 ++G+AF +++F+E Sbjct: 140 TIGQAFDLAYRKFLE 154 >gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein isoform 1 [Homo sapiens] Length = 506 Score = 43.1 bits (100), Expect = 5e-04 Identities = 40/156 (25%), Positives = 70/156 (44%), Gaps = 21/156 (13%) Query: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPS----SCVLEISVRGVKIGV 353 F K++GS+ VP V + AAM RR+ F + + +SV GVK+ + Sbjct: 32 FEAKYVGSLDVPRPNSRVEIVAAM------RRIRYEFKAKNIKKKKVSIMVSVDGVKVIL 85 Query: 354 KADDSQEAKGNKCSHFFQLK---------NISFRGYHPKNNKYFGFITKHLADHRFACHV 404 K K + + K I + + ++ K F +I + A + F C+V Sbjct: 86 KKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNV 145 Query: 405 FVSEDSTKA--LAESVGRAFQQFHKQFVEYTCPTED 438 F S+ ++A + +VG+AF+ HK +++T D Sbjct: 146 FKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNAD 181 >gi|50511947 cajalin 2 isoform b [Homo sapiens] Length = 510 Score = 42.4 bits (98), Expect = 9e-04 Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 10/129 (7%) Query: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKI-ATTRRLTVHFNPPSSCVLEISVRGVKIGVKAD 356 ++ +LGS+ + +G A K+ A ++ T + +L +S +GVK Sbjct: 312 YKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKF----- 366 Query: 357 DSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTKA--L 414 +A +++NIS P++ F +ITK L + CHVF + D A + Sbjct: 367 --IDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEI 424 Query: 415 AESVGRAFQ 423 ++G+AF+ Sbjct: 425 ILTLGQAFE 433 >gi|50511945 cajalin 2 isoform a [Homo sapiens] Length = 1248 Score = 42.4 bits (98), Expect = 9e-04 Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 10/129 (7%) Query: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKI-ATTRRLTVHFNPPSSCVLEISVRGVKIGVKAD 356 ++ +LGS+ + +G A K+ A ++ T + +L +S +GVK Sbjct: 1062 YKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKF----- 1116 Query: 357 DSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTKA--L 414 +A +++NIS P++ F +ITK L + CHVF + D A + Sbjct: 1117 --IDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEI 1174 Query: 415 AESVGRAFQ 423 ++G+AF+ Sbjct: 1175 ILTLGQAFE 1183 >gi|10047134 cajalin 2 isoform c [Homo sapiens] Length = 414 Score = 42.4 bits (98), Expect = 9e-04 Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 10/129 (7%) Query: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKI-ATTRRLTVHFNPPSSCVLEISVRGVKIGVKAD 356 ++ +LGS+ + +G A K+ A ++ T + +L +S +GVK Sbjct: 228 YKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKF----- 282 Query: 357 DSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTKA--L 414 +A +++NIS P++ F +ITK L + CHVF + D A + Sbjct: 283 --IDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEI 340 Query: 415 AESVGRAFQ 423 ++G+AF+ Sbjct: 341 ILTLGQAFE 349 >gi|140161500 ankyrin repeat and sterile alpha motif domain containing 1 [Homo sapiens] Length = 1134 Score = 41.6 bits (96), Expect = 0.001 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 12/128 (9%) Query: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADD 357 + +LGS+ + +G A K+ R+ T H + +L I+ +GVK Sbjct: 942 YEANYLGSMLIKDLRGTESTQDACAKM---RKSTEHMKKIPTIILSITYKGVKF------ 992 Query: 358 SQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVF--VSEDSTKALA 415 +A +++NIS P++ F +ITK L CHVF V + T + Sbjct: 993 -IDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEII 1051 Query: 416 ESVGRAFQ 423 ++G+AF+ Sbjct: 1052 LTLGQAFE 1059 >gi|194473700 Src homology 3 domain-containing guanine nucleotide exchange factor [Homo sapiens] Length = 871 Score = 40.0 bits (92), Expect = 0.004 Identities = 19/50 (38%), Positives = 27/50 (54%) Query: 230 FVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVT 279 F + DE L+V D +L+ + D WYE +R G RG+F A E+T Sbjct: 800 FTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEIT 849 >gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens] Length = 888 Score = 39.3 bits (90), Expect = 0.007 Identities = 19/54 (35%), Positives = 28/54 (51%) Query: 227 IFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVTK 280 I+ + PR EDE EL + LV + +D W++ +M T G F Y VT+ Sbjct: 453 IYPYTPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVAPVTR 506 Score = 35.4 bits (80), Expect = 0.10 Identities = 16/49 (32%), Positives = 25/49 (51%) Query: 222 QTHRTIFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFF 270 + HR + + P+ E E EL+ D + V + ED W++ R G G F Sbjct: 832 ERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLF 880 >gi|10863899 numb homolog (Drosophila)-like [Homo sapiens] Length = 609 Score = 38.9 bits (89), Expect = 0.009 Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 14/126 (11%) Query: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADD 357 F V++LG V+V +G V A++K+ R +V VL +S G+++ DD Sbjct: 80 FPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSV------KSVLWVSADGLRV---VDD 130 Query: 358 SQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVS-EDSTKALAE 416 K ++ +SF +K F +I + R+ CH F++ +DS + L+ Sbjct: 131 ----KTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSH 186 Query: 417 SVGRAF 422 +VG AF Sbjct: 187 AVGCAF 192 >gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens] Length = 882 Score = 37.7 bits (86), Expect = 0.021 Identities = 18/66 (27%), Positives = 33/66 (50%) Query: 227 IFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVTKEPEHMA 286 ++ + P+ DE EL + V + +D W++ ++RTG G F Y V++ P A Sbjct: 472 LYAYKPQKSDELELHKGEMYRVLEKCQDGWFKGASLRTGVSGVFPGNYVTPVSRVPAGGA 531 Query: 287 ALAKNS 292 +N+ Sbjct: 532 GPPRNN 537 Score = 34.7 bits (78), Expect = 0.18 Identities = 16/49 (32%), Positives = 25/49 (51%) Query: 222 QTHRTIFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFF 270 + +R + + P+ E E EL+ D + V + ED WY+ R G G F Sbjct: 826 ERYRVVVSYPPQSEAEIELKEGDIVFVHKKREDGWYKGTLQRNGRTGLF 874 >gi|90403598 mesoderm posterior 2 homolog [Homo sapiens] Length = 397 Score = 37.4 bits (85), Expect = 0.027 Identities = 16/32 (50%), Positives = 20/32 (62%) Query: 32 PGAGPPKAESGQEPASRGQGQSQGQSQGPGSG 63 P GP +A++ E +GQGQ QGQ QG G G Sbjct: 166 PDRGPAEAQTQAEGQGQGQGQGQGQGQGQGQG 197 Score = 32.7 bits (73), Expect = 0.68 Identities = 15/34 (44%), Positives = 18/34 (52%) Query: 30 RRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSG 63 R P +AE + +GQGQ QGQ QG G G Sbjct: 168 RGPAEAQTQAEGQGQGQGQGQGQGQGQGQGQGQG 201 >gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens] Length = 1597 Score = 37.0 bits (84), Expect = 0.036 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 230 FVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVTKEPEHMAALA 289 + PR DE LE D ++V Q+ D W E + G RG+F +E PE A Sbjct: 1521 YKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGERGWFPV-QQVEFISNPEVRAQNL 1579 Query: 290 KNSDWVDQFRVKFL 303 K + V +++ + Sbjct: 1580 KEAHRVKTAKLQLV 1593 >gi|54144629 numb homolog isoform 4 [Homo sapiens] Length = 592 Score = 36.6 bits (83), Expect = 0.047 Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 14/126 (11%) Query: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADD 357 F VK+LG V+V +G + A++++ T + V VL +S G+++ Sbjct: 39 FPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAV------KAVLWVSADGLRV------ 86 Query: 358 SQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVS-EDSTKALAE 416 + K ++ +SF ++ F +I + R+ CH F++ +D+ + L+ Sbjct: 87 -VDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSH 145 Query: 417 SVGRAF 422 +VG AF Sbjct: 146 AVGCAF 151 >gi|20070356 numb homolog isoform 3 [Homo sapiens] Length = 640 Score = 36.6 bits (83), Expect = 0.047 Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 14/126 (11%) Query: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADD 357 F VK+LG V+V +G + A++++ T + V VL +S G+++ Sbjct: 39 FPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAV------KAVLWVSADGLRV------ 86 Query: 358 SQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVS-EDSTKALAE 416 + K ++ +SF ++ F +I + R+ CH F++ +D+ + L+ Sbjct: 87 -VDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSH 145 Query: 417 SVGRAF 422 +VG AF Sbjct: 146 AVGCAF 151 >gi|50083291 amyloid beta A4 precursor protein-binding, family B, member 2 [Homo sapiens] Length = 736 Score = 36.2 bits (82), Expect = 0.061 Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 12/130 (9%) Query: 292 SDWVDQFRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKI 351 ++ V +F V++LG + V G +L++A++ + T+ N + ++V + Sbjct: 562 TELVQKFHVQYLGMLPVDKPVGMDILNSAIENLMTSS------NKEDWLSVNMNVADATV 615 Query: 352 GVKADDSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDST 411 V ++ ++E +C +++ +SF G K+ F FI + RF CHVF E + Sbjct: 616 TVISEKNEEEVLVEC----RVRFLSFMGVG-KDVHTFAFIMD-TGNQRFECHVFWCEPNA 669 Query: 412 KALAESVGRA 421 ++E+V A Sbjct: 670 GNVSEAVQAA 679 >gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo sapiens] Length = 671 Score = 36.2 bits (82), Expect = 0.061 Identities = 18/55 (32%), Positives = 29/55 (52%) Query: 224 HRTIFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEV 278 +R ++++ P++EDE EL D + V Q +D W+ + RT G F Y V Sbjct: 617 YRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 671 >gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo sapiens] Length = 329 Score = 36.2 bits (82), Expect = 0.061 Identities = 18/55 (32%), Positives = 29/55 (52%) Query: 224 HRTIFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEV 278 +R ++++ P++EDE EL D + V Q +D W+ + RT G F Y V Sbjct: 275 YRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 329 >gi|18093112 ABT1-associated protein [Homo sapiens] Length = 851 Score = 36.2 bits (82), Expect = 0.061 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 12/72 (16%) Query: 9 ATGDTPGAEDDE-EDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYR 67 A+GD G+EDDE ED+DEE K++SG + A +G G+ +T Sbjct: 265 ASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLA-----------RGKGNIETSS 313 Query: 68 PKRPTTLNLFPQ 79 T +LFP+ Sbjct: 314 EDEDDTADLFPE 325 >gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo sapiens] Length = 628 Score = 35.4 bits (80), Expect = 0.10 Identities = 18/68 (26%), Positives = 38/68 (55%), Gaps = 2/68 (2%) Query: 218 EEQEQTHRTIFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIE 277 E + + + F ++P+++DE EL+V D + V + E+ W+E + G G F + + E Sbjct: 60 ERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWE--GVLNGKTGMFPSNFIKE 117 Query: 278 VTKEPEHM 285 ++ E + + Sbjct: 118 LSGESDEL 125 >gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo sapiens] Length = 665 Score = 35.4 bits (80), Expect = 0.10 Identities = 18/68 (26%), Positives = 38/68 (55%), Gaps = 2/68 (2%) Query: 218 EEQEQTHRTIFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIE 277 E + + + F ++P+++DE EL+V D + V + E+ W+E + G G F + + E Sbjct: 97 ERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWE--GVLNGKTGMFPSNFIKE 154 Query: 278 VTKEPEHM 285 ++ E + + Sbjct: 155 LSGESDEL 162 >gi|54144627 numb homolog isoform 2 [Homo sapiens] Length = 603 Score = 35.0 bits (79), Expect = 0.14 Identities = 30/131 (22%), Positives = 59/131 (45%), Gaps = 13/131 (9%) Query: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHF-----NPPSSCVLEISVRGVKIG 352 F VK+LG V+V +G + A++++ R+ F VL +S G+++ Sbjct: 39 FPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRV- 97 Query: 353 VKADDSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVS-EDST 411 + K ++ +SF ++ F +I + R+ CH F++ +D+ Sbjct: 98 ------VDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTG 151 Query: 412 KALAESVGRAF 422 + L+ +VG AF Sbjct: 152 ERLSHAVGCAF 162 >gi|54144625 numb homolog isoform 1 [Homo sapiens] Length = 651 Score = 35.0 bits (79), Expect = 0.14 Identities = 30/131 (22%), Positives = 59/131 (45%), Gaps = 13/131 (9%) Query: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHF-----NPPSSCVLEISVRGVKIG 352 F VK+LG V+V +G + A++++ R+ F VL +S G+++ Sbjct: 39 FPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRV- 97 Query: 353 VKADDSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVS-EDST 411 + K ++ +SF ++ F +I + R+ CH F++ +D+ Sbjct: 98 ------VDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTG 151 Query: 412 KALAESVGRAF 422 + L+ +VG AF Sbjct: 152 ERLSHAVGCAF 162 >gi|49640014 ubiquitin associated and SH3 domain containing, A short form [Homo sapiens] Length = 623 Score = 35.0 bits (79), Expect = 0.14 Identities = 36/141 (25%), Positives = 56/141 (39%), Gaps = 17/141 (12%) Query: 222 QTHRTIFRFVPRHEDEPELEVDDPLLVEL----QAEDYWYEAYNMRTGARGFFTAYYAIE 277 QT R +F++ P++ DE L D + V+ +A + W + RTG RGF Sbjct: 241 QTLRALFQYKPQNVDELTLSPGDYIFVDPTQQDEASEGWVIGISQRTGCRGFL------- 293 Query: 278 VTKEPEHMAALAKNSD-WVDQFRVKFLGSVQVPYHK-GDVVLSAAMQKIATTRRLTVHFN 335 PE+ A SD WV F + + K G+ + + + T R Sbjct: 294 ----PENYTDRASESDTWVKHRMYTFSLATDLNSRKDGEASSRCSGEFLPQTARSLSSLQ 349 Query: 336 PPSSCVLEISVRGVKIGVKAD 356 + V SV V+ G + D Sbjct: 350 ALQATVARKSVLVVRHGERVD 370 >gi|9507221 ubiquitin associated and SH3 domain containing, A long form [Homo sapiens] Length = 661 Score = 35.0 bits (79), Expect = 0.14 Identities = 36/141 (25%), Positives = 56/141 (39%), Gaps = 17/141 (12%) Query: 222 QTHRTIFRFVPRHEDEPELEVDDPLLVEL----QAEDYWYEAYNMRTGARGFFTAYYAIE 277 QT R +F++ P++ DE L D + V+ +A + W + RTG RGF Sbjct: 279 QTLRALFQYKPQNVDELTLSPGDYIFVDPTQQDEASEGWVIGISQRTGCRGFL------- 331 Query: 278 VTKEPEHMAALAKNSD-WVDQFRVKFLGSVQVPYHK-GDVVLSAAMQKIATTRRLTVHFN 335 PE+ A SD WV F + + K G+ + + + T R Sbjct: 332 ----PENYTDRASESDTWVKHRMYTFSLATDLNSRKDGEASSRCSGEFLPQTARSLSSLQ 387 Query: 336 PPSSCVLEISVRGVKIGVKAD 356 + V SV V+ G + D Sbjct: 388 ALQATVARKSVLVVRHGERVD 408 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 35.0 bits (79), Expect = 0.14 Identities = 28/112 (25%), Positives = 44/112 (39%), Gaps = 8/112 (7%) Query: 9 ATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEP-------ASRGQGQSQGQSQGPG 61 AT +D++ D +E++A RP P ++ +G EP A R G Q + P Sbjct: 327 ATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPL 386 Query: 62 SGDTYRPKRPTTLNLFPQVQLSQDTLNNNSLGKKY-KQPRPHHRSRHLHQQP 112 S + P + S + L +S + P+P SRH P Sbjct: 387 SQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,196,364 Number of Sequences: 37866 Number of extensions: 942680 Number of successful extensions: 6889 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 80 Number of HSP's successfully gapped in prelim test: 119 Number of HSP's that attempted gapping in prelim test: 6462 Number of HSP's gapped (non-prelim): 459 length of query: 442 length of database: 18,247,518 effective HSP length: 105 effective length of query: 337 effective length of database: 14,271,588 effective search space: 4809525156 effective search space used: 4809525156 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.