Guide to the Human Genome
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Search of human proteins with 239740946

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239740946 PREDICTED: hypothetical protein XP_002344104
isoform 1 [Homo sapiens]
         (430 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239740946 PREDICTED: hypothetical protein XP_002344104 isofor...   828   0.0  
gi|239740944 PREDICTED: hypothetical protein XP_002344105 isofor...   828   0.0  
gi|239740942 PREDICTED: hypothetical protein XP_002344106 isofor...   828   0.0  
gi|32698714 hypothetical protein LOC284058 [Homo sapiens]             823   0.0  
gi|40217794 hypothetical protein LOC151050 [Homo sapiens]              47   3e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         42   8e-04
gi|21493045 A-kinase anchor protein 6 [Homo sapiens]                   37   0.026
gi|4502805 chromogranin A precursor [Homo sapiens]                     37   0.045
gi|8923040 CDKN2A interacting protein [Homo sapiens]                   34   0.22 
gi|8922940 gamma-taxilin [Homo sapiens]                                34   0.29 
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]           33   0.38 
gi|46852390 coiled-coil domain containing 6 [Homo sapiens]             33   0.38 
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  33   0.38 
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        33   0.50 
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    33   0.50 
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   33   0.65 
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]          33   0.65 
gi|206725422 G protein-coupled receptor kinase interacting ArfGA...    32   0.85 
gi|17149830 G protein-coupled receptor kinase interacting ArfGAP...    32   0.85 
gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo s...    32   1.1  
gi|51173722 bromodomain and PHD finger-containing protein 1 isof...    32   1.1  
gi|51173720 bromodomain and PHD finger-containing protein 1 isof...    32   1.1  
gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo s...    32   1.5  
gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo sap...    32   1.5  
gi|221316754 exophilin 5 isoform c [Homo sapiens]                      32   1.5  
gi|221316751 exophilin 5 isoform b [Homo sapiens]                      32   1.5  
gi|5803145 ralA binding protein 1 [Homo sapiens]                       32   1.5  
gi|221316747 exophilin 5 isoform a [Homo sapiens]                      32   1.5  
gi|46409304 glutamate-rich 1 [Homo sapiens]                            32   1.5  
gi|90403581 meiosis defective 1 [Homo sapiens]                         32   1.5  

>gi|239740946 PREDICTED: hypothetical protein XP_002344104 isoform 1
           [Homo sapiens]
          Length = 430

 Score =  828 bits (2138), Expect = 0.0
 Identities = 430/430 (100%), Positives = 430/430 (100%)

Query: 1   MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 60
           MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
Sbjct: 1   MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 60

Query: 61  LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYEL 120
           LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYEL
Sbjct: 61  LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYEL 120

Query: 121 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 180
           RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
Sbjct: 121 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 180

Query: 181 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQP 240
           RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQP
Sbjct: 181 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQP 240

Query: 241 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 300
           ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
Sbjct: 241 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 300

Query: 301 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 360
           LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
Sbjct: 301 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 360

Query: 361 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 420
           TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
Sbjct: 361 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 420

Query: 421 ADPEQRHVPL 430
           ADPEQRHVPL
Sbjct: 421 ADPEQRHVPL 430


>gi|239740944 PREDICTED: hypothetical protein XP_002344105 isoform 2
           [Homo sapiens]
          Length = 430

 Score =  828 bits (2138), Expect = 0.0
 Identities = 430/430 (100%), Positives = 430/430 (100%)

Query: 1   MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 60
           MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
Sbjct: 1   MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 60

Query: 61  LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYEL 120
           LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYEL
Sbjct: 61  LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYEL 120

Query: 121 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 180
           RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
Sbjct: 121 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 180

Query: 181 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQP 240
           RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQP
Sbjct: 181 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQP 240

Query: 241 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 300
           ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
Sbjct: 241 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 300

Query: 301 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 360
           LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
Sbjct: 301 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 360

Query: 361 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 420
           TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
Sbjct: 361 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 420

Query: 421 ADPEQRHVPL 430
           ADPEQRHVPL
Sbjct: 421 ADPEQRHVPL 430


>gi|239740942 PREDICTED: hypothetical protein XP_002344106 isoform 3
           [Homo sapiens]
          Length = 430

 Score =  828 bits (2138), Expect = 0.0
 Identities = 430/430 (100%), Positives = 430/430 (100%)

Query: 1   MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 60
           MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
Sbjct: 1   MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 60

Query: 61  LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYEL 120
           LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYEL
Sbjct: 61  LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYEL 120

Query: 121 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 180
           RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
Sbjct: 121 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 180

Query: 181 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQP 240
           RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQP
Sbjct: 181 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQP 240

Query: 241 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 300
           ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
Sbjct: 241 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 300

Query: 301 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 360
           LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
Sbjct: 301 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 360

Query: 361 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 420
           TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
Sbjct: 361 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 420

Query: 421 ADPEQRHVPL 430
           ADPEQRHVPL
Sbjct: 421 ADPEQRHVPL 430


>gi|32698714 hypothetical protein LOC284058 [Homo sapiens]
          Length = 1105

 Score =  823 bits (2127), Expect = 0.0
 Identities = 428/430 (99%), Positives = 429/430 (99%)

Query: 1   MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 60
           MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
Sbjct: 1   MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 60

Query: 61  LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYEL 120
           LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFS QTVLKSHPLLSQSYEL
Sbjct: 61  LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL 120

Query: 121 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 180
           RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
Sbjct: 121 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 180

Query: 181 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQP 240
           RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYS+NSTANKSSVNSMEQP
Sbjct: 181 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP 240

Query: 241 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 300
           ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
Sbjct: 241 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 300

Query: 301 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 360
           LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
Sbjct: 301 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 360

Query: 361 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 420
           TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
Sbjct: 361 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 420

Query: 421 ADPEQRHVPL 430
           ADPEQRHVPL
Sbjct: 421 ADPEQRHVPL 430


>gi|40217794 hypothetical protein LOC151050 [Homo sapiens]
          Length = 987

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 9/142 (6%)

Query: 283 RITALLRRQADIESRARRLQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRS 342
           R+   + +Q  + S+ARR QK LQ++ AK V +H   Q+   ++    +LP +++    +
Sbjct: 223 RLLHCVSKQKILLSQARRTQKHLQMLLAKHVVKHYGQQMKLSMKH---QLPKMKTFHEPT 279

Query: 343 QLMLTRKAEAALRKAASETTTSEGLSNFLKSNSISE----ELERFTASGIANLRCSEQAF 398
            ++     +    K    T T+E        N  +     E++RF  S    L   E+  
Sbjct: 280 TILGNSLPKCTEIKPEVNTLTAENKLWDDAKNGFARCTAAEIQRFAFSATGLLSHVEEGL 339

Query: 399 DSDVTDSSSGGESDIEEEELTR 420
           DSD TDSSS  + D++E  L +
Sbjct: 340 DSDATDSSS--DDDLDEYTLRK 359


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 10/140 (7%)

Query: 150  PQAPVNGLAKKLTKSSTHSDHDNSTSLNGGKRALTSSALHGGEMGGSESGDLKG------ 203
            P++P    A++           +S+S +G   + +SS+  G E  G E GD  G      
Sbjct: 2541 PKSPDKAQAEQ---DGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGT 2597

Query: 204  GMTNCTLPH-RSLDVEHTTLYSDNSTANKSSVNSMEQPALQGSSRLSPGTDSSSNLGGVK 262
            G  NC+    R+     ++  S +S+++ SS +S    +   SS  S  + SSS+     
Sbjct: 2598 GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2657

Query: 263  LEGKKSPLSSILFSALDSDT 282
                 S  SS   S  D D+
Sbjct: 2658 SSSSSSSSSSSSSSTTDEDS 2677


>gi|21493045 A-kinase anchor protein 6 [Homo sapiens]
          Length = 2319

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 10/129 (7%)

Query: 155  NGLAKKLTKSSTHSDHDNSTSLNGGKRALTSSALHGGEM---GGSESGDLKGGMTNCTLP 211
            N L K L+K S+ S   +   L GG   +   A HGG+M    GSESG +  G T  T  
Sbjct: 1318 NVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTN 1377

Query: 212  H-----RSLDVEHTTLYSDNSTANK-SSVNSMEQPAL-QGSSRLSPGTDSSSNLGGVKLE 264
                   ++D   + L +++       +VN ++Q    +G S   P +  SS      + 
Sbjct: 1378 SEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVN 1437

Query: 265  GKKSPLSSI 273
            GK   L+SI
Sbjct: 1438 GKVGDLNSI 1446


>gi|4502805 chromogranin A precursor [Homo sapiens]
          Length = 457

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 36/163 (22%)

Query: 269 PLSSILFSALDSDTRITALLRRQADIESRARRLQKRLQ--VVQAKQVERHIQHQLGGFLE 326
           P+S   F  L  D RI ++LR Q         L K LQ   +Q  +   H Q +  GF +
Sbjct: 51  PVSQECFETLRGDERILSILRHQ--------NLLKELQDLALQGAKERAHQQKKHSGFED 102

Query: 327 KTLSKLPNLESLRPRSQLMLTRKAEAALRKAASETTTSEGLSNFLKSNSISEELERFTAS 386
           +              S+++  + ++A L++A  E ++ +     ++    S+E E+   S
Sbjct: 103 EL-------------SEVLENQSSQAELKEAVEEPSSKD----VMEKREDSKEAEK---S 142

Query: 387 GIANLRCSEQAFDSDVTDS------SSGGESDIEEEELTRADP 423
           G A      QA    + +S       + GE + EEEE T   P
Sbjct: 143 GEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEEATNTHP 185


>gi|8923040 CDKN2A interacting protein [Homo sapiens]
          Length = 580

 Score = 34.3 bits (77), Expect = 0.22
 Identities = 52/215 (24%), Positives = 85/215 (39%), Gaps = 15/215 (6%)

Query: 134 SLENLRTMNTSGQTALPQAP-VNGLAK--KLTKSSTHSDHDNSTSLNGGKRALTSSALHG 190
           S+ +  T   SG+ +  +AP  +G A    L KSS +S    ST       +   SAL G
Sbjct: 217 SVSSQVTTAGSGKASEAEAPDKHGSASFVSLLKSSVNSHMTQSTDSRQQSGSPKKSALEG 276

Query: 191 GEMGGSESGDL-------KGGMTNCTLPHRSLDVEHTTLYSD--NSTANKSSVNSM--EQ 239
                S+S            G +   LP  S      T  S   + T++++SV+S   + 
Sbjct: 277 SSASASQSSSEIEVPLLGSSGSSEVELPLLSSKPSSETASSGLTSKTSSEASVSSSVAKN 336

Query: 240 PALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRAR 299
            +  G+S L+P + SS+N   +  +      +S+L S   S T   +L+ +   + S ++
Sbjct: 337 SSSSGTSLLTPKSSSSTNTSLLTSKSTSQVAASLLASKSSSQTS-GSLVSKSTSLASVSQ 395

Query: 300 RLQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPN 334
              K        Q+      Q      K   KL N
Sbjct: 396 LASKSSSQTSTSQLPSKSTSQSSESSVKFSCKLTN 430


>gi|8922940 gamma-taxilin [Homo sapiens]
          Length = 528

 Score = 33.9 bits (76), Expect = 0.29
 Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 15/150 (10%)

Query: 244 GSSRLSPGT---DSSSNLGGVKLEGKKSPLSSILFSALDS-DTRITALLRRQADIESRAR 299
           G +R  P     DS  N    K  GK+  L     + L + + ++ AL ++ AD+   +R
Sbjct: 112 GEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESR 171

Query: 300 RLQKRLQVVQAKQVE-----RHIQHQLGGFLEKTLSKLPNLESL-RPRSQLMLTRKAEAA 353
            +QK+++++Q KQ +      H+Q +      K +     LESL R   +   T K E  
Sbjct: 172 SVQKQMKILQKKQAQIVKEKVHLQSE----HSKAILARSKLESLCRELQRHNKTLKEENM 227

Query: 354 LRKAASETTTSEGLSNF-LKSNSISEELER 382
            +    E    E  ++F +  + I  +LE+
Sbjct: 228 QQAREEEERRKEATAHFQITLDEIQAQLEQ 257


>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
          Length = 1958

 Score = 33.5 bits (75), Expect = 0.38
 Identities = 48/203 (23%), Positives = 85/203 (41%), Gaps = 25/203 (12%)

Query: 91   PSKESLKLQGVF-STQTVLKSHPLLSQSYELRAELLGRQPVLEFSLENLRTMNTSGQTAL 149
            PS    +L  VF   + V + H    +  +  +E LGR+  +  + EN    +T    + 
Sbjct: 1430 PSSSEDELDNVFFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKEN----STRKDPST 1485

Query: 150  PQAPVNGLAKKLTKSST-----HSDHDNSTSLN-------GGKRALTSSALHGGEMGGSE 197
             +     L K+ T S       +S H+ S +L+          R+L +      E  GS+
Sbjct: 1486 TKDEKISLGKESTPSEEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSD 1545

Query: 198  SGDLKGGMTNCTLPHRSL------DVEHTTLYSDNST--ANKSSVNSMEQPALQGSSRLS 249
            SG L    +  +L   S+      + +H+   ++ ST  ++ S+ +S        SSRLS
Sbjct: 1546 SGTLLSTSSQASLARFSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLS 1605

Query: 250  PGTDSSSNLGGVKLEGKKSPLSS 272
            P   S +   G + + ++S L S
Sbjct: 1606 PEVQSVAESKGDEADDERSELIS 1628


>gi|46852390 coiled-coil domain containing 6 [Homo sapiens]
          Length = 474

 Score = 33.5 bits (75), Expect = 0.38
 Identities = 40/195 (20%), Positives = 82/195 (42%), Gaps = 8/195 (4%)

Query: 157 LAKKLTKSSTHSDHDNSTSLNGGKRALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLD 216
           +A   ++S T     NS+S    + + +S++  GG  GG   G   GG+         L 
Sbjct: 1   MADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELT 60

Query: 217 VEHTTLYSDNSTAN-KSSVNSMEQPALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILF 275
               +L  +N     +     ++  ALQ  +R       +S     + E ++  +S+ LF
Sbjct: 61  NRLASLQQENKVLKIELETYKLKCKALQEENR---DLRKASVTIQARAEQEEEFISNTLF 117

Query: 276 SALDS--DTRITALLRRQADIESRARRLQKRLQVVQAK--QVERHIQHQLGGFLEKTLSK 331
             + +    + T  +  + + E     L ++L  +Q +  ++E+H++ +    + K + K
Sbjct: 118 KKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKK 177

Query: 332 LPNLESLRPRSQLML 346
           +  LE+     QL L
Sbjct: 178 IKKLENDTISKQLTL 192


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 33.5 bits (75), Expect = 0.38
 Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 21/149 (14%)

Query: 291  QADIESRARRLQKRLQ-----------VVQAKQVERHIQHQLG-----GFLEKTLSKLPN 334
            + ++E   R +QKR Q           ++   ++E+ ++H          +EKTL K   
Sbjct: 1374 ECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLK--R 1431

Query: 335  LESLRPRSQLMLTRKAEAALRKAASETTT---SEGLSNFLKSNSISEELERFTASGIANL 391
               LR   +L+   ++E +  K  ++      ++   + L++ S +EELER       NL
Sbjct: 1432 RSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNL 1491

Query: 392  RCSEQAFDSDVTDSSSGGESDIEEEELTR 420
              ++Q   S   D+    +  I++EE+ +
Sbjct: 1492 VKADQQLRSLQADAKDLEQHKIKQEEILK 1520


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 33.1 bits (74), Expect = 0.50
 Identities = 61/296 (20%), Positives = 105/296 (35%), Gaps = 32/296 (10%)

Query: 25   PSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPSLDFRNNPTKEDLGKLQPLVASYLC 84
            P+ST +PG +E +    +  ++ G+    +        F ++ T    G+      S   
Sbjct: 1288 PASTTTPGLSEES--TTVYSSSRGSTETTV--------FPHSTTTSVHGEEPTTFHSRPA 1337

Query: 85   SDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYELRAELLGRQPVLEFSLENLRTMNTS 144
            S  T++ +++S    G+    T     P  +Q+      L       +   E+    ++S
Sbjct: 1338 STHTTLFTEDSTT-SGLTEESTAFPGSPASTQT-----GLPATLTTADLGEESTTFPSSS 1391

Query: 145  GQTALPQAPV----NGLAKKLTKSSTHSDHDNSTSLNGGKRALTSSALHGGEMGGSESGD 200
            G T    +P     +GL  + T S        +T+L G     + S           S D
Sbjct: 1392 GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 1451

Query: 201  L---------KGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQPALQGSSR--LS 249
                       G     +  H      HTT + D++T +  S       + QGS+   LS
Sbjct: 1452 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 1511

Query: 250  PGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARRLQKRL 305
            PG+ ++S+LG        SP      + L  DT  + L+       S    L   L
Sbjct: 1512 PGSTTASSLGQQSTTFHSSP-GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 1566



 Score = 32.3 bits (72), Expect = 0.85
 Identities = 67/286 (23%), Positives = 107/286 (37%), Gaps = 30/286 (10%)

Query: 5    APALTDAAAE---AHHIRFKLAPPSSTLS---PGSAENNGNANILIAANGTKRKAIAAED 58
            AP+ T A  E   ++H     + P ST +   P S+  +G +    A++ ++        
Sbjct: 3511 APSTTSALVEEPTSYH-----SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 3565

Query: 59   PSLDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSY 118
            P+     + T   LG+      S    + T++P   S    G+    T   S P  S + 
Sbjct: 3566 PA----RSTTSVLLGESTTSPISSGSMETTALPG--STTTPGLSEKSTTFHSSPR-SPAT 3618

Query: 119  ELRAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVN-GLAKKLTKSSTHSDHDNSTSLN 177
             L         V E S  +     ++  TA P +    GL++  T S +     ++T L 
Sbjct: 3619 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 3678

Query: 178  GGKRALTSS--ALHGGEMGGSESGDLKGGMTNC-------TLPHRSLDVEHTTLYSDNST 228
                   SS  +       GS    L  G T         T  H S    HTTL+ D++T
Sbjct: 3679 ASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTT 3738

Query: 229  ANKSSVNSMEQPALQGSSR--LSPGTDSSSNLGGVKLEGKKSPLSS 272
            ++     S    +  GS R  LSP + +S  L G     +  P S+
Sbjct: 3739 SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 3784



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 61/296 (20%), Positives = 104/296 (35%), Gaps = 32/296 (10%)

Query: 25   PSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPSLDFRNNPTKEDLGKLQPLVASYLC 84
            P+ST +PG +E +    +  ++ G+    +        F  + T    G+      S   
Sbjct: 2845 PASTTTPGLSEES--TTVYSSSPGSTETTV--------FPRSTTTSVRGEEPTTFHSRPA 2894

Query: 85   SDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYELRAELLGRQPVLEFSLENLRTMNTS 144
            S  T++ +++S    G+    T     P  +Q+      L       +   E+    ++S
Sbjct: 2895 STHTTLFTEDSTT-SGLTEESTAFPGSPASTQT-----GLPATLTTADLGEESTTFPSSS 2948

Query: 145  GQTALPQAPV----NGLAKKLTKSSTHSDHDNSTSLNGGKRALTSSALHGGEMGGSESGD 200
            G T    +P     +GL  + T S        +T+L G     + S           S D
Sbjct: 2949 GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 3008

Query: 201  L---------KGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQPALQGSSR--LS 249
                       G     +  H      HTT + D++T +  S       + QGS+   LS
Sbjct: 3009 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLS 3068

Query: 250  PGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARRLQKRL 305
            PG+ ++S+LG        SP      + L  DT  + L+       S    L   L
Sbjct: 3069 PGSTTASSLGQQSTTFHSSP-GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 3123



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 65/298 (21%), Positives = 102/298 (34%), Gaps = 36/298 (12%)

Query: 25   PSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPSLDFRNN-PTKEDLGKLQPLVASYL 83
            P+ST +PG +E +    +  ++ G+    +     +   R   PT             + 
Sbjct: 3928 PASTTTPGLSEES--TTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFT 3985

Query: 84   CSDVTSVPSKESLKLQGV-FSTQTVLKSHPLLSQSYELRAELLGRQPVLEFSLENLRTMN 142
                TS  ++ES    G   STQT L +         L    LG         E+    +
Sbjct: 3986 EDSTTSGLTEESTAFPGSPASTQTGLPA--------TLTTADLGE--------ESTTFPS 4029

Query: 143  TSGQTALPQAPV----NGLAKKLTKSSTHSDHDNSTSLNGGKRALTSSALHGGEMGGSES 198
            +SG T    +P     +GL  + T S        +T+L G     + S           S
Sbjct: 4030 SSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 4089

Query: 199  GDL---------KGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQPALQGSSR-- 247
             D           G     +  H      HTT + D++T +  S       + QGS+   
Sbjct: 4090 PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEAT 4149

Query: 248  LSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARRLQKRL 305
            LSPG+ ++S+LG        SP      + L  DT  + L+       S    L   L
Sbjct: 4150 LSPGSTTASSLGQQSTTFHSSP-GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 4206



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 65/287 (22%), Positives = 111/287 (38%), Gaps = 32/287 (11%)

Query: 5    APALTDAAAE---AHHIRFKLAPPSSTLS---PGSAENNGNANILIAANGTKRKAIAAED 58
            AP+ T A  E   ++H     + P ST +   P S+  +G +    A++ ++        
Sbjct: 871  APSTTSALVEEPTSYH-----SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 925

Query: 59   PSLDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSY 118
            P+     + T   LG+      S    + T++P   S    G+    T   S P  S + 
Sbjct: 926  PA----RSTTSVLLGESTTSPISSGSMETTALPG--STTTPGLSERSTTFHSSPR-SPAT 978

Query: 119  ELRAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVN-GLAKKLTKSSTHSDHDN----- 172
             L         V E S  +     ++  TA P +    GL++  T S +     +     
Sbjct: 979  TLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 1038

Query: 173  -STSLNGGKRALTSSALHGGE----MGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNS 227
             ST+ +G  +  T+S    G     +    +  L  G  + T  H +    HTTL+ D++
Sbjct: 1039 ASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF-HSNPGSTHTTLFPDST 1097

Query: 228  TANKSSVNSMEQPALQGSSR--LSPGTDSSSNLGGVKLEGKKSPLSS 272
            T++     S    +  GS R  LSP + +S  L G     +  P S+
Sbjct: 1098 TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 1144



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 30/114 (26%), Positives = 45/114 (39%), Gaps = 8/114 (7%)

Query: 161  LTKSSTHSDHDNSTSLNGGKRALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHT 220
            L  S+T S     ++ +      T +AL  G       G         T  H S    HT
Sbjct: 2120 LPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQ------ESTTFHSSPGSTHT 2173

Query: 221  TLYSDNSTANKSSVNSMEQPALQGSSR--LSPGTDSSSNLGGVKLEGKKSPLSS 272
            TL+ D++T++     S    +  GS R  LSP + +S  L G     +  P S+
Sbjct: 2174 TLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 2227



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 30/114 (26%), Positives = 45/114 (39%), Gaps = 8/114 (7%)

Query: 161  LTKSSTHSDHDNSTSLNGGKRALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHT 220
            L  S+T S     ++ +      T +AL  G       G         T  H S    HT
Sbjct: 2594 LPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQ------ESTTFHSSPGSTHT 2647

Query: 221  TLYSDNSTANKSSVNSMEQPALQGSSR--LSPGTDSSSNLGGVKLEGKKSPLSS 272
            TL+ D++T++     S    +  GS R  LSP + +S  L G     +  P S+
Sbjct: 2648 TLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPAST 2701


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 33.1 bits (74), Expect = 0.50
 Identities = 61/296 (20%), Positives = 105/296 (35%), Gaps = 32/296 (10%)

Query: 25   PSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPSLDFRNNPTKEDLGKLQPLVASYLC 84
            P+ST +PG +E +    +  ++ G+    +        F ++ T    G+      S   
Sbjct: 775  PASTTTPGLSEES--TTVYSSSRGSTETTV--------FPHSTTTSVHGEEPTTFHSRPA 824

Query: 85   SDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSYELRAELLGRQPVLEFSLENLRTMNTS 144
            S  T++ +++S    G+    T     P  +Q+      L       +   E+    ++S
Sbjct: 825  STHTTLFTEDSTT-SGLTEESTAFPGSPASTQT-----GLPATLTTADLGEESTTFPSSS 878

Query: 145  GQTALPQAPV----NGLAKKLTKSSTHSDHDNSTSLNGGKRALTSSALHGGEMGGSESGD 200
            G T    +P     +GL  + T S        +T+L G     + S           S D
Sbjct: 879  GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 938

Query: 201  L---------KGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQPALQGSSR--LS 249
                       G     +  H      HTT + D++T +  S       + QGS+   LS
Sbjct: 939  ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 998

Query: 250  PGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARRLQKRL 305
            PG+ ++S+LG        SP      + L  DT  + L+       S    L   L
Sbjct: 999  PGSTTASSLGQQSTTFHSSP-GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 1053



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 65/287 (22%), Positives = 111/287 (38%), Gaps = 32/287 (11%)

Query: 5   APALTDAAAE---AHHIRFKLAPPSSTLS---PGSAENNGNANILIAANGTKRKAIAAED 58
           AP+ T A  E   ++H     + P ST +   P S+  +G +    A++ ++        
Sbjct: 358 APSTTSALVEEPTSYH-----SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 412

Query: 59  PSLDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSTQTVLKSHPLLSQSY 118
           P+     + T   LG+      S    + T++P   S    G+    T   S P  S + 
Sbjct: 413 PA----RSTTSVLLGESTTSPISSGSMETTALPG--STTTPGLSERSTTFHSSPR-SPAT 465

Query: 119 ELRAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVN-GLAKKLTKSSTHSDHDN----- 172
            L         V E S  +     ++  TA P +    GL++  T S +     +     
Sbjct: 466 TLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 525

Query: 173 -STSLNGGKRALTSSALHGGE----MGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNS 227
            ST+ +G  +  T+S    G     +    +  L  G  + T  H +    HTTL+ D++
Sbjct: 526 ASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF-HSNPGSTHTTLFPDST 584

Query: 228 TANKSSVNSMEQPALQGSSR--LSPGTDSSSNLGGVKLEGKKSPLSS 272
           T++     S    +  GS R  LSP + +S  L G     +  P S+
Sbjct: 585 TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 631


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 32.7 bits (73), Expect = 0.65
 Identities = 37/164 (22%), Positives = 70/164 (42%), Gaps = 6/164 (3%)

Query: 161 LTKSSTHSDHDNSTSLNGGKRALTSSALHGGEMGGSESGDLKGGMTNCTLPH----RSLD 216
           + +S+T +  ++S + NG   +  SS L  G   G  SGD    ++   L H    ++L 
Sbjct: 2   MQESATETISNSSMNQNG--MSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQ 59

Query: 217 VEHTTLYSDNSTANKSSVNSMEQPALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFS 276
                L    ++  KS  +S +Q  LQ    ++  T        ++   ++  LS     
Sbjct: 60  AARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQ 119

Query: 277 ALDSDTRITALLRRQADIESRARRLQKRLQVVQAKQVERHIQHQ 320
           AL    +   L ++Q     + ++ Q  LQ++Q +Q ++  Q Q
Sbjct: 120 ALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQ 163


>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
          Length = 1711

 Score = 32.7 bits (73), Expect = 0.65
 Identities = 44/181 (24%), Positives = 77/181 (42%), Gaps = 24/181 (13%)

Query: 196 SESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQPALQGSSRLSPGTDSS 255
           S+ G LK  M + TL  +  DV+    +S    A +  +  +EQ  L+ S +L   T + 
Sbjct: 410 SDRGSLKSIMQSNTLT-KDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTV 468

Query: 256 SNLGGV------------------KLEGKKSPLSSILFSALDSDTRITALLRRQA-DIES 296
            +L G                   ++E  K+ ++    + L+     T  LR++  D   
Sbjct: 469 QSLHGSSRALSNSNRDKEIKKLNEEIERLKNKIADS--NRLERQLEDTVALRQEREDSTQ 526

Query: 297 RARRLQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRK 356
           R R L+K+ +VV+ ++ E H   QL    E+  S+   L+    + +L L   +E   R 
Sbjct: 527 RLRGLEKQHRVVRQEKEELH--KQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERM 584

Query: 357 A 357
           A
Sbjct: 585 A 585


>gi|206725422 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 5 [Homo sapiens]
          Length = 729

 Score = 32.3 bits (72), Expect = 0.85
 Identities = 36/161 (22%), Positives = 66/161 (40%), Gaps = 19/161 (11%)

Query: 197 ESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQPALQ---GSSRLSPGTD 253
           +   L G   N  L  ++++ +H+    DN   +  SV S E   L+     +      D
Sbjct: 358 QGSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKSLD 417

Query: 254 SSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARRLQKRLQVVQA--- 310
           S  + G V ++        +  + + S+ +I  L++   ++    R +QK+LQ +Q+   
Sbjct: 418 SDLSDGPVTVQ----EFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQKKLQTLQSENS 473

Query: 311 ---KQVERHI-QHQLGGFLEKT-----LSKLPNLESLRPRS 342
              KQ   ++ Q Q G     T     L + P+    RP S
Sbjct: 474 NLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMS 514


>gi|17149830 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 1 [Homo sapiens]
          Length = 759

 Score = 32.3 bits (72), Expect = 0.85
 Identities = 36/161 (22%), Positives = 66/161 (40%), Gaps = 19/161 (11%)

Query: 197 ESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQPALQ---GSSRLSPGTD 253
           +   L G   N  L  ++++ +H+    DN   +  SV S E   L+     +      D
Sbjct: 358 QGSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKSLD 417

Query: 254 SSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARRLQKRLQVVQA--- 310
           S  + G V ++        +  + + S+ +I  L++   ++    R +QK+LQ +Q+   
Sbjct: 418 SDLSDGPVTVQ----EFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQKKLQTLQSENS 473

Query: 311 ---KQVERHI-QHQLGGFLEKT-----LSKLPNLESLRPRS 342
              KQ   ++ Q Q G     T     L + P+    RP S
Sbjct: 474 NLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMS 514


>gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo
           sapiens]
          Length = 444

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 8/107 (7%)

Query: 319 HQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASET-TTSEGLSNFL-----K 372
           H  GG  +K L  +  L+  +P S  +++R + ++ R+A SET   S+ LS        K
Sbjct: 128 HLEGGSDQKDL--VQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHK 185

Query: 373 SNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELT 419
           S+SIS   +   A  +    C E++  S+ T + S  + D    ++T
Sbjct: 186 SDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVYQVT 232


>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform 2
            [Homo sapiens]
          Length = 1214

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 12/123 (9%)

Query: 150  PQAPVNGLAKKLTKS-----STHSDHDNSTSLNGGKRALTSSALHGGEMGGSESGDLKGG 204
            PQ P+    ++  +      S+ SD D+  S       L ++   GG     +S  +   
Sbjct: 931  PQLPIMSSLRQRKRGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVY-- 988

Query: 205  MTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQPALQGSSRLSPGT---DSSSNLGGV 261
              +C+LP  S D E ++  S ++ ++++S    +Q   +G    S GT   DSS +  G 
Sbjct: 989  RNDCSLPRSSSDSESSSSSSSSAASDRTSTTPSKQG--RGKPSFSRGTFPEDSSEDTSGT 1046

Query: 262  KLE 264
            + E
Sbjct: 1047 ENE 1049


>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform 1
            [Homo sapiens]
          Length = 1220

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 12/123 (9%)

Query: 150  PQAPVNGLAKKLTKS-----STHSDHDNSTSLNGGKRALTSSALHGGEMGGSESGDLKGG 204
            PQ P+    ++  +      S+ SD D+  S       L ++   GG     +S  +   
Sbjct: 937  PQLPIMSSLRQRKRGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVY-- 994

Query: 205  MTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQPALQGSSRLSPGT---DSSSNLGGV 261
              +C+LP  S D E ++  S ++ ++++S    +Q   +G    S GT   DSS +  G 
Sbjct: 995  RNDCSLPRSSSDSESSSSSSSSAASDRTSTTPSKQG--RGKPSFSRGTFPEDSSEDTSGT 1052

Query: 262  KLE 264
            + E
Sbjct: 1053 ENE 1055


>gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo
           sapiens]
          Length = 452

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 8/100 (8%)

Query: 319 HQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASET-TTSEGLSNFL-----K 372
           H  GG  +K L  +  L+  +P S  +++R + ++ R+A SET   S+ LS        K
Sbjct: 89  HLEGGSDQKDL--VQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHK 146

Query: 373 SNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESD 412
           S+SIS   +   A  +    C E++  S+ T + S  + D
Sbjct: 147 SDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLD 186


>gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo
           sapiens]
          Length = 497

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 8/100 (8%)

Query: 319 HQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASET-TTSEGLSNFL-----K 372
           H  GG  +K L  +  L+  +P S  +++R + ++ R+A SET   S+ LS        K
Sbjct: 134 HLEGGSDQKDL--VQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHK 191

Query: 373 SNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESD 412
           S+SIS   +   A  +    C E++  S+ T + S  + D
Sbjct: 192 SDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLD 231


>gi|221316754 exophilin 5 isoform c [Homo sapiens]
          Length = 1801

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 57/252 (22%), Positives = 98/252 (38%), Gaps = 21/252 (8%)

Query: 131  LEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGKRALTSSALHG 190
            L+ S+ + +T+ T   TA   +    LA  L + ++     +        R + S  L  
Sbjct: 1126 LKMSVNSDQTLTTENMTAFRLSNRGPLAPTLQEMASVEAAVSLPEEESKAREIFSDNLAK 1185

Query: 191  GEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQ-----PALQ-- 243
              +G SE+   +G        H SL ++   +  + S   + S+NS        PAL   
Sbjct: 1186 TPLGDSENKKERGKKLQSETLHTSLMLQRKNVSEEKSENCQQSINSSNSGPSSLPALSEV 1245

Query: 244  --GSSRLSPGTDSSSNLG-GVKLEGK-KSPLSSILFSALDSDTRITALLRRQADIESRAR 299
              G+S+    +   +  G  +   G  K P      +A+   +  +     + DI +  +
Sbjct: 1246 NIGNSQTRRSSWECTGSGRAIPFTGSGKCPQKDHTSTAVGDGSSGSQPREGRGDIGTNCQ 1305

Query: 300  RLQKRLQVVQAKQVERHI----QHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAAL- 354
            ++  +       QV        + QLG   E+T S  PNLESL+   + +  R  EA + 
Sbjct: 1306 KMTNKTLSHSESQVFALTPALHKLQLG---EETQSDEPNLESLQSEPRELPQRSQEANMT 1362

Query: 355  --RKAASETTTS 364
              RKA  E   S
Sbjct: 1363 ESRKAEDEMQKS 1374


>gi|221316751 exophilin 5 isoform b [Homo sapiens]
          Length = 1913

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 57/252 (22%), Positives = 98/252 (38%), Gaps = 21/252 (8%)

Query: 131  LEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGKRALTSSALHG 190
            L+ S+ + +T+ T   TA   +    LA  L + ++     +        R + S  L  
Sbjct: 1238 LKMSVNSDQTLTTENMTAFRLSNRGPLAPTLQEMASVEAAVSLPEEESKAREIFSDNLAK 1297

Query: 191  GEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQ-----PALQ-- 243
              +G SE+   +G        H SL ++   +  + S   + S+NS        PAL   
Sbjct: 1298 TPLGDSENKKERGKKLQSETLHTSLMLQRKNVSEEKSENCQQSINSSNSGPSSLPALSEV 1357

Query: 244  --GSSRLSPGTDSSSNLG-GVKLEGK-KSPLSSILFSALDSDTRITALLRRQADIESRAR 299
              G+S+    +   +  G  +   G  K P      +A+   +  +     + DI +  +
Sbjct: 1358 NIGNSQTRRSSWECTGSGRAIPFTGSGKCPQKDHTSTAVGDGSSGSQPREGRGDIGTNCQ 1417

Query: 300  RLQKRLQVVQAKQVERHI----QHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAAL- 354
            ++  +       QV        + QLG   E+T S  PNLESL+   + +  R  EA + 
Sbjct: 1418 KMTNKTLSHSESQVFALTPALHKLQLG---EETQSDEPNLESLQSEPRELPQRSQEANMT 1474

Query: 355  --RKAASETTTS 364
              RKA  E   S
Sbjct: 1475 ESRKAEDEMQKS 1486


>gi|5803145 ralA binding protein 1 [Homo sapiens]
          Length = 655

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 35/161 (21%), Positives = 73/161 (45%), Gaps = 10/161 (6%)

Query: 260 GVKLEGKKSP-LSSILFSALDSDTRITALLRRQADIESRARRLQKRLQVVQAKQVERHIQ 318
           G+K E ++   L + L   L    +  +   R  +++     L+++L+  + ++ E  I 
Sbjct: 397 GIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLWEVQRILTALKRKLREAKRQECETKIA 456

Query: 319 HQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASETTTSEGLSNFLKSNSISE 378
            ++    ++ +SK    E +    +++    A+    +  +E      +  FL+    SE
Sbjct: 457 QEIASLSKEDVSK----EEMNENEEVINILLAQE--NEILTEQEELLAMEQFLRRQIASE 510

Query: 379 --ELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEE 417
             E+ER  A  IA ++  +Q   S+  + SS  ES+ E+EE
Sbjct: 511 KEEIERLRAE-IAEIQSRQQHGRSETEEYSSESESESEDEE 550


>gi|221316747 exophilin 5 isoform a [Homo sapiens]
          Length = 1989

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 57/252 (22%), Positives = 98/252 (38%), Gaps = 21/252 (8%)

Query: 131  LEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGKRALTSSALHG 190
            L+ S+ + +T+ T   TA   +    LA  L + ++     +        R + S  L  
Sbjct: 1314 LKMSVNSDQTLTTENMTAFRLSNRGPLAPTLQEMASVEAAVSLPEEESKAREIFSDNLAK 1373

Query: 191  GEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSDNSTANKSSVNSMEQ-----PALQ-- 243
              +G SE+   +G        H SL ++   +  + S   + S+NS        PAL   
Sbjct: 1374 TPLGDSENKKERGKKLQSETLHTSLMLQRKNVSEEKSENCQQSINSSNSGPSSLPALSEV 1433

Query: 244  --GSSRLSPGTDSSSNLG-GVKLEGK-KSPLSSILFSALDSDTRITALLRRQADIESRAR 299
              G+S+    +   +  G  +   G  K P      +A+   +  +     + DI +  +
Sbjct: 1434 NIGNSQTRRSSWECTGSGRAIPFTGSGKCPQKDHTSTAVGDGSSGSQPREGRGDIGTNCQ 1493

Query: 300  RLQKRLQVVQAKQVERHI----QHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAAL- 354
            ++  +       QV        + QLG   E+T S  PNLESL+   + +  R  EA + 
Sbjct: 1494 KMTNKTLSHSESQVFALTPALHKLQLG---EETQSDEPNLESLQSEPRELPQRSQEANMT 1550

Query: 355  --RKAASETTTS 364
              RKA  E   S
Sbjct: 1551 ESRKAEDEMQKS 1562


>gi|46409304 glutamate-rich 1 [Homo sapiens]
          Length = 443

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 34/148 (22%), Positives = 61/148 (41%), Gaps = 19/148 (12%)

Query: 289 RRQADIESRARRLQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTR 348
           +R+   + ++++  K    V  +Q E   Q  L    EK+  +  +  ++    +  L +
Sbjct: 110 KRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSL--LQEKSQRQHTDGTTISKNKKRKLKK 167

Query: 349 KAEAALRKAASETTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSG 408
           K +   +KAA     + G+S   +    S E E     G+    C E   D+   D +  
Sbjct: 168 KQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGE-----GVGEA-CEEDGVDTSEEDPTLA 221

Query: 409 GESDIE-----------EEELTRADPEQ 425
           GE D++           EE+LTRA  E+
Sbjct: 222 GEEDVKDTREEDGADASEEDLTRARQEE 249


>gi|90403581 meiosis defective 1 [Homo sapiens]
          Length = 1274

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 9/66 (13%)

Query: 98  LQGVFSTQTVLKSHPLLSQSYELRAELLGR--QPVLEF-------SLENLRTMNTSGQTA 148
           L+G+   Q V   HPLL + + L  EL+ R    VLE        S E L  + ++GQ A
Sbjct: 766 LEGIPDLQLVYTHHPLLLRFFLLYPELMSRYGHRVLELWFFWEESSYEELDDVTSAGQPA 825

Query: 149 LPQAPV 154
           LP + V
Sbjct: 826 LPASLV 831


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.124    0.330 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,090,745
Number of Sequences: 37866
Number of extensions: 635555
Number of successful extensions: 2533
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 2424
Number of HSP's gapped (non-prelim): 166
length of query: 430
length of database: 18,247,518
effective HSP length: 105
effective length of query: 325
effective length of database: 14,271,588
effective search space: 4638266100
effective search space used: 4638266100
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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