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Search of human proteins with 23592238
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23592238 glucose transporter 14 [Homo sapiens]
(520 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23592238 glucose transporter 14 [Homo sapiens] 1025 0.0
gi|5902090 solute carrier family 2 (facilitated glucose transpor... 924 0.0
gi|166795299 solute carrier family 2 (facilitated glucose transp... 618 e-177
gi|4507011 glucose transporter 4 [Homo sapiens] 541 e-154
gi|4557851 solute carrier family 2 (facilitated glucose transpor... 482 e-136
gi|134053883 intestinal facilitative glucose transporter 7 [Homo... 353 2e-97
gi|4507013 solute carrier family 2 (facilitated glucose/fructose... 350 1e-96
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ... 323 3e-88
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ... 323 3e-88
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi... 286 2e-77
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] 284 2e-76
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] 284 2e-76
gi|21361449 solute carrier family 2 (facilitated glucose transpo... 202 6e-52
gi|203098995 solute carrier family 2 (facilitated glucose transp... 162 9e-40
gi|207447703 solute carrier family 2 (facilitated glucose/fructo... 149 6e-36
gi|223029432 solute carrier family 2 (facilitated glucose transp... 142 6e-34
gi|223029430 solute carrier family 2 (facilitated glucose transp... 140 3e-33
gi|21553331 solute carrier family 2 (facilitated glucose transpo... 125 1e-28
gi|13540547 solute carrier family 2 member 10 [Homo sapiens] 96 6e-20
gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 65 1e-10
gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 60 5e-09
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 59 1e-08
gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 57 3e-08
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 56 7e-08
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 56 9e-08
gi|8923870 solute carrier family 22 member 11 [Homo sapiens] 49 1e-05
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens] 46 9e-05
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 45 1e-04
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 45 1e-04
gi|31542327 solute carrier family 22, member 16 [Homo sapiens] 45 2e-04
>gi|23592238 glucose transporter 14 [Homo sapiens]
Length = 520
Score = 1025 bits (2650), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MEFHNGGHVSGIGGFLVSLTSRMKPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPET 60
MEFHNGGHVSGIGGFLVSLTSRMKPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPET
Sbjct: 1 MEFHNGGHVSGIGGFLVSLTSRMKPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPET 60
Query: 61 IIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLI 120
IIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLI
Sbjct: 61 IIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLI 120
Query: 121 VNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGT 180
VNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGT
Sbjct: 121 VNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGT 180
Query: 181 LNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINR 240
LNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINR
Sbjct: 181 LNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINR 240
Query: 241 KKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVL 300
KKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVL
Sbjct: 241 KKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVL 300
Query: 301 QLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHM 360
QLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHM
Sbjct: 301 QLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHM 360
Query: 361 IGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQG 420
IGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQG
Sbjct: 361 IGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQG 420
Query: 421 PRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGR 480
PRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGR
Sbjct: 421 PRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGR 480
Query: 481 TFEDITRAFEGQAHGADRSGKDGVMGMNSIEPAKETTTNV 520
TFEDITRAFEGQAHGADRSGKDGVMGMNSIEPAKETTTNV
Sbjct: 481 TFEDITRAFEGQAHGADRSGKDGVMGMNSIEPAKETTTNV 520
>gi|5902090 solute carrier family 2 (facilitated glucose
transporter), member 3 [Homo sapiens]
Length = 496
Score = 924 bits (2388), Expect = 0.0
Identities = 469/494 (94%), Positives = 482/494 (97%)
Query: 27 TLAVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNL 86
T VTPALIFAITVATIGSFQFGYNTGVINAPE IIKEFINKTLTDK NAPPSEVLLT+L
Sbjct: 3 TQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSL 62
Query: 87 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLIL 146
WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLA TGGC MGLCK+A+SVEMLIL
Sbjct: 63 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLIL 122
Query: 147 GRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEE 206
GRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIV+GILVAQIFGLE ILGSEE
Sbjct: 123 GRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEE 182
Query: 207 LWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEM 266
LWP+LLGFTILPAILQSAALP CPESPRFLLINRK+EENA +ILQRLWGTQDVSQDIQEM
Sbjct: 183 LWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEM 242
Query: 267 KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ 326
KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ
Sbjct: 243 KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ 302
Query: 327 QPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGM 386
+PIYATI AGVVNTIFT++SLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLK++YNGM
Sbjct: 303 EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGM 362
Query: 387 SFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 446
SFVCIGAILVFVA FEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS
Sbjct: 363 SFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 422
Query: 447 AAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVMG 506
AA+YLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVM
Sbjct: 423 AAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVME 482
Query: 507 MNSIEPAKETTTNV 520
MNSIEPAKETTTNV
Sbjct: 483 MNSIEPAKETTTNV 496
>gi|166795299 solute carrier family 2 (facilitated glucose
transporter), member 1 [Homo sapiens]
Length = 492
Score = 618 bits (1593), Expect = e-177
Identities = 306/481 (63%), Positives = 381/481 (79%), Gaps = 1/481 (0%)
Query: 23 MKPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVL 82
M+P + +T L+ A+ A +GS QFGYNTGVINAP+ +I+EF N+T +
Sbjct: 1 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT 60
Query: 83 LTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVE 142
LT LWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML++NLLA LMG K+ +S E
Sbjct: 61 LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE 120
Query: 143 MLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELIL 202
MLILGR +IG++CGL TGFVPMY+GE+SPTALRGA GTL+QLGIV+GIL+AQ+FGL+ I+
Sbjct: 121 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM 180
Query: 203 GSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQD 262
G+++LWP+LL +PA+LQ LP CPESPRFLLINR +E A +L++L GT DV+ D
Sbjct: 181 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD 240
Query: 263 IQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKD 322
+QEMK+ES +M +EK+VT+LELFR +YRQPI+I++VLQLSQQLSGINAVFYYST IF+
Sbjct: 241 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK 300
Query: 323 AGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNH 382
AGVQQP+YATI +G+VNT FT++SLF+VERAGRRTLH+IGL GMA C+ LMT++L L
Sbjct: 301 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ 360
Query: 383 YNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGL 442
MS++ I AI FVA FE+GPGPIPWFIVAELFSQGPRPAA+AVAG SNWTSNF+VG+
Sbjct: 361 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420
Query: 443 LFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF-EGQAHGADRSGK 501
F G YVFIIFT L+ F FT+FKVPET+GRTF++I F +G A +D++ +
Sbjct: 421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE 480
Query: 502 D 502
+
Sbjct: 481 E 481
>gi|4507011 glucose transporter 4 [Homo sapiens]
Length = 509
Score = 541 bits (1395), Expect = e-154
Identities = 280/470 (59%), Positives = 348/470 (74%), Gaps = 4/470 (0%)
Query: 24 KPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKT-LTDKANAPPSEV- 81
+P VT L+ A+ A +GS QFGYN GVINAP+ +I++ N+T L + PS +
Sbjct: 14 EPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIP 73
Query: 82 --LLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAE 139
LT LW+LSVAIFSVGGMI SF +G+ GR+ +ML+ N+LA GG LMGL A
Sbjct: 74 PGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAA 133
Query: 140 SVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLE 199
S EMLILGR +IG + GL +G VPMY+GEI+PT LRGA GTLNQL IVIGIL+AQ+ GLE
Sbjct: 134 SYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLE 193
Query: 200 LILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDV 259
+LG+ LWP+LLG T+LPA+LQ LP CPESPR+L I + E A + L+RL G DV
Sbjct: 194 SLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADV 253
Query: 260 SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGI 319
S + E+KDE ++ +E+ +++L+L ++RQP+II++VLQLSQQLSGINAVFYYST I
Sbjct: 254 SGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSI 313
Query: 320 FKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLL 379
F+ AGV QP YATI AGVVNT+FTL+S+ LVERAGRRTLH++GL GM C+ LMTV+LLL
Sbjct: 314 FETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLL 373
Query: 380 KNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFL 439
MS+V I AI FVA FEIGPGPIPWFIVAELFSQGPRPAAMAVAG SNWTSNF+
Sbjct: 374 LERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFI 433
Query: 440 VGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 489
+G+ F A +G YVF++F L+ F FTF +VPETRGRTF+ I+ AF
Sbjct: 434 IGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAF 483
>gi|4557851 solute carrier family 2 (facilitated glucose
transporter), member 2 [Homo sapiens]
Length = 524
Score = 482 bits (1240), Expect = e-136
Identities = 249/503 (49%), Positives = 338/503 (67%), Gaps = 34/503 (6%)
Query: 30 VTPALIFAITVATIGSFQFGYNTGVINAPETII--------------KEFINK------- 68
VT L+F + A +GSFQFGY+ GVINAP+ +I ++ IN
Sbjct: 6 VTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINSTD 65
Query: 69 ---TLTDKANAPPSE----------VLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRR 115
T++ N P+ L+T LWSLSV+ F+VGGM SF G + GR
Sbjct: 66 ELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRI 125
Query: 116 NSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALR 175
+ML+ N+L+ G LMG K+ S ++I GR + GL+CGL +G VPMYIGEI+PTALR
Sbjct: 126 KAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALR 185
Query: 176 GAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRF 235
GA GT +QL IV GIL++QI GLE ILG+ +LW +LLG + + AILQS L CPESPR+
Sbjct: 186 GALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRY 245
Query: 236 LLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPII 295
L I +E A + L+RL G DV++DI EM+ E S E++V++++LF SSYRQPI+
Sbjct: 246 LYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPIL 305
Query: 296 ISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGR 355
++++L ++QQ SGIN +FYYST IF+ AG+ +P+YATI G VN +FT +S+FLVE+AGR
Sbjct: 306 VALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGR 365
Query: 356 RTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAE 415
R+L +IG+ GM C+ M+V L+L N ++ MS+V + AI +FV+ FEIGPGPIPWF+VAE
Sbjct: 366 RSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAE 425
Query: 416 LFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVP 475
FSQGPRPAA+A+A SNWT NF+V L F A + G YVF +F G L+ F FTFFKVP
Sbjct: 426 FFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVP 485
Query: 476 ETRGRTFEDITRAFEGQAHGADR 498
ET+G++FE+I F+ ++ A R
Sbjct: 486 ETKGKSFEEIAAEFQKKSGSAHR 508
>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
sapiens]
Length = 512
Score = 353 bits (906), Expect = 2e-97
Identities = 190/491 (38%), Positives = 290/491 (59%), Gaps = 5/491 (1%)
Query: 32 PALIFAITVATIGS-FQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLS 90
P L+ A A GS FQ+GYN V+N P + K F N+T ++ L+ LWS +
Sbjct: 21 PTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCT 80
Query: 91 VAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLV 150
V++F +GG++GS VGL V+ GR+ ++LI N+ A LMG+ K+A++ E+++ R+V
Sbjct: 81 VSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVV 140
Query: 151 IGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPV 210
+G+ G+ +PMY+GE++P LRG GT+ ++ +++G+ +AQIF L+ ILG+ WPV
Sbjct: 141 LGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPV 200
Query: 211 LLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDES 270
LL T +PA+LQ LP PESPR+ LI + E A + L+RL G D+ ++++M+ E+
Sbjct: 201 LLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEA 260
Query: 271 ARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ--QP 328
E ++VL L + S R ++ IVL QQLSGINA+ YY+ I+ AGV+
Sbjct: 261 RAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAAHS 320
Query: 329 IYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSF 388
Y T+ +GVVN + T+ S LVER GRR L + G G ++TV LL +N +S+
Sbjct: 321 QYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSY 380
Query: 389 VCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAA 448
+ I + ++A IGP P+P + E+F Q R AA V G +W +NF++G LFPS
Sbjct: 381 LGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQ 440
Query: 449 YYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVM--G 506
+GAY FIIF G + + + +PET+G+TF +I R F + K+ + G
Sbjct: 441 EAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEKEETIDAG 500
Query: 507 MNSIEPAKETT 517
+ PAKET+
Sbjct: 501 PPTASPAKETS 511
>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 1 [Homo sapiens]
Length = 501
Score = 350 bits (899), Expect = 1e-96
Identities = 184/463 (39%), Positives = 277/463 (59%), Gaps = 3/463 (0%)
Query: 30 VTPALIFAITVATIGS-FQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWS 88
+T L A +A GS FQ+GYN +N+P ++++F N+T + + LT LWS
Sbjct: 13 LTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWS 72
Query: 89 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGR 148
++V++F GG IGS VG VN+FGR+ ++L N+ + LMG ++A S E++I+ R
Sbjct: 73 VTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISR 132
Query: 149 LVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELW 208
L++G+ G+ + VPMY+GE++P LRGA G + QL I +GILVAQIFGL +L + + W
Sbjct: 133 LLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGW 192
Query: 209 PVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKD 268
P+LLG T +PA LQ LP PESPR+LLI +K E A + LQ L G V +++ E++
Sbjct: 193 PILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQ 252
Query: 269 ESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV--Q 326
E ++VL+LFR+ S R ++ IVL QQLSG+NA++YY+ I+ AGV +
Sbjct: 253 EDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEE 312
Query: 327 QPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGM 386
Y T G VN + T ++F+VE GRR L ++G ++T +L L++ + M
Sbjct: 313 HVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWM 372
Query: 387 SFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 446
++ I ++ +V +GP PIP ++ E+F Q RP+A V G +W SNF VGL+FP
Sbjct: 373 PYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPF 432
Query: 447 AAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 489
LG Y FI+F + + F VPET+ +TF +I + F
Sbjct: 433 IQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIF 475
>gi|47933389 solute carrier family 2, member 9 protein isoform 2
[Homo sapiens]
Length = 511
Score = 323 bits (827), Expect = 3e-88
Identities = 171/458 (37%), Positives = 262/458 (57%), Gaps = 2/458 (0%)
Query: 34 LIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAI 93
L+ ++ A SF +GYN V+NAP IK F N++ + P LT LWS++V+I
Sbjct: 28 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 87
Query: 94 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGL 153
F++GG++G+ V + GR++++L N A + LM A + EMLI+GR ++G+
Sbjct: 88 FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 147
Query: 154 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLG 213
G+ +PMY+ EISP +RG+ G + + I IG+ Q+ GL +LG E WP L G
Sbjct: 148 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 207
Query: 214 FTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARM 273
++PA++Q +LP P+SPR+LL+ + E A + Q G DVSQ+++E+ ES
Sbjct: 208 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 267
Query: 274 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV--QQPIYA 331
+ V+VLEL R R ++ IV QL G+NA+++Y+ IF AG+ + Y
Sbjct: 268 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 327
Query: 332 TISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCI 391
T+S G + T+ + S ++E GRR L + G G M +T++L L++H + ++ I
Sbjct: 328 TLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSI 387
Query: 392 GAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYL 451
IL +A F GPG IP+ + E F Q RPAA +AG NW SNF VGLLFP L
Sbjct: 388 VGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSL 447
Query: 452 GAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 489
Y F++F IT + +F +PET+ RT+ +I++AF
Sbjct: 448 DTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAF 485
>gi|47933387 solute carrier family 2, member 9 protein isoform 1
[Homo sapiens]
Length = 540
Score = 323 bits (827), Expect = 3e-88
Identities = 171/458 (37%), Positives = 262/458 (57%), Gaps = 2/458 (0%)
Query: 34 LIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAI 93
L+ ++ A SF +GYN V+NAP IK F N++ + P LT LWS++V+I
Sbjct: 57 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 116
Query: 94 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGL 153
F++GG++G+ V + GR++++L N A + LM A + EMLI+GR ++G+
Sbjct: 117 FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 176
Query: 154 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLG 213
G+ +PMY+ EISP +RG+ G + + I IG+ Q+ GL +LG E WP L G
Sbjct: 177 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 236
Query: 214 FTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARM 273
++PA++Q +LP P+SPR+LL+ + E A + Q G DVSQ+++E+ ES
Sbjct: 237 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 296
Query: 274 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV--QQPIYA 331
+ V+VLEL R R ++ IV QL G+NA+++Y+ IF AG+ + Y
Sbjct: 297 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 356
Query: 332 TISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCI 391
T+S G + T+ + S ++E GRR L + G G M +T++L L++H + ++ I
Sbjct: 357 TLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSI 416
Query: 392 GAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYL 451
IL +A F GPG IP+ + E F Q RPAA +AG NW SNF VGLLFP L
Sbjct: 417 VGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSL 476
Query: 452 GAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 489
Y F++F IT + +F +PET+ RT+ +I++AF
Sbjct: 477 DTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAF 514
>gi|190684655 glucose transporter protein 10 isoform a [Homo
sapiens]
Length = 503
Score = 286 bits (733), Expect = 2e-77
Identities = 159/472 (33%), Positives = 261/472 (55%), Gaps = 3/472 (0%)
Query: 19 LTSRMKPHTLAVTPALIFAITVATIG-SFQFGYNTGVINAPETIIKEFINKTLTDKANAP 77
L ++P T L+ I A IG +FQFGYN +INAP I+EF N+T + P
Sbjct: 5 LEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 64
Query: 78 PSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKI 137
+ L+ +WSL V+++ +GG+ G+ G GR+ S+L+ N+ + L G +
Sbjct: 65 LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 124
Query: 138 AESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFG 197
A S EM++LGRL++G+ G+ PMY+GE +P LRGA + + +GI++ Q+ G
Sbjct: 125 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 184
Query: 198 LELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQ 257
L +LG + WP+LL ++P LQ A+LP PESPR+LLI+ E L+RL G+
Sbjct: 185 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 244
Query: 258 DVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYST 317
D++ +++E+++E A + ELF+ + R+ + +VL + +L G ++V+ Y++
Sbjct: 245 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 304
Query: 318 GIFKDAGVQQP--IYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTV 375
+F+ AGV + YA I G + ++S ++ER GRR L + G M ++ TV
Sbjct: 305 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 364
Query: 376 SLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWT 435
+L L++ + ++ + I F+ F IGP + + ELF Q RPAA V G W
Sbjct: 365 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 424
Query: 436 SNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 487
LVGL FP L ++++ F G + +T +PET+G+TF++I++
Sbjct: 425 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 476
>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
Length = 496
Score = 284 bits (726), Expect = 2e-76
Identities = 156/457 (34%), Positives = 256/457 (56%), Gaps = 3/457 (0%)
Query: 34 LIFAITVATIG-SFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVA 92
L+ I A IG +FQFGYN +INAP I+EF N+T + P + L+ +WSL V+
Sbjct: 13 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 72
Query: 93 IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIG 152
++ +GG+ G+ G GR+ S+L+ N+ + L G + A S EM++LGRL++G
Sbjct: 73 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 132
Query: 153 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLL 212
+ G+ PMY+GE +P LRGA + + +GI++ Q+ GL +LG + WP+LL
Sbjct: 133 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 192
Query: 213 GFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESAR 272
++P LQ A+LP PESPR+LLI+ E L+RL G+ D++ +++E+++E A
Sbjct: 193 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 252
Query: 273 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQP--IY 330
+ ELF+ + R+ + +VL + +L G ++V+ Y++ +F+ AGV + Y
Sbjct: 253 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 312
Query: 331 ATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVC 390
A I G + ++S ++ER GRR L + G M ++ TV+L L++ + ++
Sbjct: 313 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 372
Query: 391 IGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYY 450
+ I F+ F IGP + + ELF Q RPAA V G W LVGL FP
Sbjct: 373 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 432
Query: 451 LGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 487
L ++++ F G + +T +PET+G+TF++I++
Sbjct: 433 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 469
>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
Length = 499
Score = 284 bits (726), Expect = 2e-76
Identities = 156/457 (34%), Positives = 256/457 (56%), Gaps = 3/457 (0%)
Query: 34 LIFAITVATIG-SFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVA 92
L+ I A IG +FQFGYN +INAP I+EF N+T + P + L+ +WSL V+
Sbjct: 16 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75
Query: 93 IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIG 152
++ +GG+ G+ G GR+ S+L+ N+ + L G + A S EM++LGRL++G
Sbjct: 76 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135
Query: 153 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLL 212
+ G+ PMY+GE +P LRGA + + +GI++ Q+ GL +LG + WP+LL
Sbjct: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195
Query: 213 GFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESAR 272
++P LQ A+LP PESPR+LLI+ E L+RL G+ D++ +++E+++E A
Sbjct: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255
Query: 273 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQP--IY 330
+ ELF+ + R+ + +VL + +L G ++V+ Y++ +F+ AGV + Y
Sbjct: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315
Query: 331 ATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVC 390
A I G + ++S ++ER GRR L + G M ++ TV+L L++ + ++
Sbjct: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375
Query: 391 IGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYY 450
+ I F+ F IGP + + ELF Q RPAA V G W LVGL FP
Sbjct: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435
Query: 451 LGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 487
L ++++ F G + +T +PET+G+TF++I++
Sbjct: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 472
>gi|21361449 solute carrier family 2 (facilitated glucose
transporter), member 8 [Homo sapiens]
Length = 477
Score = 202 bits (514), Expect = 6e-52
Identities = 146/481 (30%), Positives = 236/481 (49%), Gaps = 51/481 (10%)
Query: 34 LIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAI 93
+ A A +G FG+ G + ++ APP+ L S A+
Sbjct: 26 VFLAAFAAALGPLSFGFALGYSSPAIPSLQRA----------APPAPRLDDAAASWFGAV 75
Query: 94 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGL 153
++G G G V+R GR+ S+L+ ++ G + A+ V ML+ GRL+ GL
Sbjct: 76 VTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAG---FAVITAAQDVWMLLGGRLLTGL 132
Query: 154 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLG 213
CG+ + P+YI EI+ A+RG G+ QL +V+GIL+A + G L E W +LG
Sbjct: 133 ACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVL----EWRWLAVLG 188
Query: 214 FTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARM 273
+P L + PE+PRFLL +++E A L+ LWG++ +D ++S +
Sbjct: 189 --CVPPSLMLLLMCFMPETPRFLLTQHRRQE-AMAALRFLWGSEQGWEDPPIGAEQSFHL 245
Query: 274 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATI 333
+ L R +P II + L QQLSG+NAV +Y+ IF++A + A++
Sbjct: 246 A---------LLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASV 296
Query: 334 SAGVVNTIFTLLSLFLVERAGRRTLHMI---------------------GLGGMAFCSTL 372
GV+ +FT ++ +++RAGRR L ++ G G + +
Sbjct: 297 VVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAIS 356
Query: 373 MTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCS 432
VS + G++++ +G++ +F+A F +G GPIPW +++E+F + A + +
Sbjct: 357 APVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLT 416
Query: 433 NWTSNFLVGLLFPSAAYYLGAY-VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEG 491
NW FLV F S L Y F + + F I + FT F VPET+G+T E IT FEG
Sbjct: 417 NWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEG 476
Query: 492 Q 492
+
Sbjct: 477 R 477
>gi|203098995 solute carrier family 2 (facilitated glucose
transporter), member 13 [Homo sapiens]
Length = 648
Score = 162 bits (409), Expect = 9e-40
Identities = 113/357 (31%), Positives = 179/357 (50%), Gaps = 27/357 (7%)
Query: 31 TPALIFAITV-ATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSL 89
TPA ++ + V + +G F FGY+TGV++ ++K ++ L LW
Sbjct: 77 TPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKR---------------QLSLDALWQE 121
Query: 90 SVAIFSVGGMIGSFSVGLFVNR-FGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGR 148
+ +VG S G +N FGRR ++L+ + L G ++ A + E L+ GR
Sbjct: 122 LLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAA---ANNKETLLAGR 178
Query: 149 LVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELW 208
LV+GL G+ + VP+YI E+SP LRG T+N L I G A + ++ W
Sbjct: 179 LVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGW 238
Query: 209 PVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKD 268
+LG +PA++Q PESPR+ LI + + + A RIL ++ G Q + ++ +K+
Sbjct: 239 RYMLGLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKN 297
Query: 269 ESARMSQEKQVTVLELFRVSSY---RQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV 325
+E + R+ SY R+ +I+ LQ+ QQLSGIN + YYS I + +GV
Sbjct: 298 NIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGV 357
Query: 326 QQPIYATISAGV---VNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLL 379
+ A A V N IFTL+ ++LVE+ GRR L L G ++ + +L
Sbjct: 358 EDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVL 414
Score = 64.7 bits (156), Expect = 2e-10
Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Query: 387 SFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 446
S+ + +++++ F G GP+PW + +E++ R A + NW N LV L F
Sbjct: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565
Query: 447 AAYYLGAY-VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKD 502
A YL Y F ++ GF L F + +PET+G+ E+I F+ + S D
Sbjct: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSD 622
>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 2 [Homo sapiens]
Length = 244
Score = 149 bits (376), Expect = 6e-36
Identities = 74/176 (42%), Positives = 113/176 (64%), Gaps = 1/176 (0%)
Query: 30 VTPALIFAITVATIGS-FQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWS 88
+T L A +A GS FQ+GYN +N+P ++++F N+T + + LT LWS
Sbjct: 13 LTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWS 72
Query: 89 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGR 148
++V++F GG IGS VG VN+FGR+ ++L N+ + LMG ++A S E++I+ R
Sbjct: 73 VTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISR 132
Query: 149 LVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGS 204
L++G+ G+ + VPMY+GE++P LRGA G + QL I +GILVAQIFGL +L +
Sbjct: 133 LLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLAN 188
>gi|223029432 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 1 [Homo sapiens]
Length = 507
Score = 142 bits (359), Expect = 6e-34
Identities = 130/484 (26%), Positives = 216/484 (44%), Gaps = 51/484 (10%)
Query: 34 LIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAI 93
+ A A +G+F FGY V +P + + ++L + S+ S ++
Sbjct: 38 VFLATFAAVLGNFSFGYAL-VYTSP---VIPALERSLDPDLHLTKSQA------SWFGSV 87
Query: 94 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGL 153
F++G G S + + GR+ S++ + +A G LM A + ML+LGR + G
Sbjct: 88 FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG---AHGLWMLLLGRTLTGF 144
Query: 154 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLG 213
GL +P+Y+ EI+P +RGA G QL V G L ++ L L+L W L
Sbjct: 145 AGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL--SLYALGLLLP----WRWLAV 198
Query: 214 FTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQ-DVSQDIQEMKDESAR 272
P ++ L P SPRFLL +R ++E A R L L GT DV + ++++D R
Sbjct: 199 AGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRR 257
Query: 273 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYAT 332
Q +V+ E R +PI ++++++L QQL+GI + Y IF V P
Sbjct: 258 --QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD 314
Query: 333 IS-AGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSL------LLKNHYNG 385
+ G V + L++ ++ AGR+ L + M + + + + L N G
Sbjct: 315 AAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTAG 374
Query: 386 -------------------MSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAM 426
++ V + A ++F+ + +G GPI W +++E+ R A
Sbjct: 375 LESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVAS 434
Query: 427 AVAGCSNWTSNFLVGLLFPSAAYYLGAYV-FIIFTGFLITFLAFTFFKVPETRGRTFEDI 485
+ ++W + F++ F G V F F + L FT VPET+GR+ E I
Sbjct: 435 GLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 494
Query: 486 TRAF 489
F
Sbjct: 495 ESFF 498
>gi|223029430 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 2 [Homo sapiens]
Length = 445
Score = 140 bits (353), Expect = 3e-33
Identities = 125/459 (27%), Positives = 203/459 (44%), Gaps = 63/459 (13%)
Query: 34 LIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAI 93
+ A A +G+F FGY V +P + + ++L + S+ S ++
Sbjct: 38 VFLATFAAVLGNFSFGYAL-VYTSP---VIPALERSLDPDLHLTKSQA------SWFGSV 87
Query: 94 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGL 153
F++G G S + + GR+ S++ + +A G LM A + ML+LGR + G
Sbjct: 88 FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG---AHGLWMLLLGRTLTGF 144
Query: 154 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLG 213
GL +P+Y+ EI+P +RGA G QL V G L ++ L L+L W L
Sbjct: 145 AGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL--SLYALGLLLP----WRWLAV 198
Query: 214 FTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQ-DVSQDIQEMKDESAR 272
P ++ L P SPRFLL +R ++E A R L L GT DV + ++++D R
Sbjct: 199 AGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRR 257
Query: 273 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYAT 332
Q +V+ E R +PI ++++++L QQL+GI + Y IF V P
Sbjct: 258 --QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD 314
Query: 333 IS-AGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCI 391
+ G V + L++ ++ AGR+
Sbjct: 315 AAIVGAVRLLSVLIAALTMDLAGRK----------------------------------- 339
Query: 392 GAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYL 451
+L+FV+ + +G GPI W +++E+ R A + ++W + F++ F
Sbjct: 340 --VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTF 397
Query: 452 GAYV-FIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 489
G V F F + L FT VPET+GR+ E I F
Sbjct: 398 GLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFF 436
>gi|21553331 solute carrier family 2 (facilitated glucose
transporter), member 12 [Homo sapiens]
Length = 617
Score = 125 bits (313), Expect = 1e-28
Identities = 96/354 (27%), Positives = 177/354 (50%), Gaps = 28/354 (7%)
Query: 41 ATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMI 100
A + GY G+I+ IK + + ++ + V+ +G ++
Sbjct: 47 AAVSGLLVGYELGIISGALLQIKTLLALSCHEQ--------------EMVVSSLVIGALL 92
Query: 101 GSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTG 160
S + G+ ++R+GRR ++++ + L G ++ L + S +LI+GR+ IG+ L +
Sbjct: 93 ASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLIL---SLSYTVLIVGRIAIGVSISLSSI 149
Query: 161 FVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAI 220
+YI EI+P RG +LN+L IVIGIL A I W + G I +
Sbjct: 150 ATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNY-AFANVFHGWKYMFGLVIPLGV 208
Query: 221 LQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVT 280
LQ+ A+ P SPRFL++ + +E A+++L RL D ++++ +K + + E Q +
Sbjct: 209 LQAIAMYFLPPSPRFLVM-KGQEGAASKVLGRLRALSDTTEELTVIK---SSLKDEYQYS 264
Query: 281 VLELFR-VSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISA---G 336
+LFR + R I+I + L Q++G + +Y++ + K G Q A++++ G
Sbjct: 265 FWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVG 324
Query: 337 VVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVC 390
VV I T+ + LV+ G +T IG MA ++L+T+ ++ N + + +C
Sbjct: 325 VVKVISTIPATLLVDHVGSKTFLCIGSSVMA--ASLVTMGIVNLNIHMNFTHIC 376
Score = 73.6 bits (179), Expect = 4e-13
Identities = 36/102 (35%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Query: 386 MSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFP 445
+ ++ + ++LV+VA F IG GP+PW +++E+F G R AMA+ NW N L+ L F
Sbjct: 460 LKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFL 519
Query: 446 SAAYYLG-AYVFIIFTGFLITFLAFTFFKVPETRGRTFEDIT 486
+ +G +V I+T + L F +PET+G + E I+
Sbjct: 520 TVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQIS 561
>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
Length = 541
Score = 96.3 bits (238), Expect = 6e-20
Identities = 92/341 (26%), Positives = 152/341 (44%), Gaps = 43/341 (12%)
Query: 32 PALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSV 91
P L +V+ +G FGY VI+ + L + E L+ +L
Sbjct: 6 PVLPLCASVSLLGGLTFGYELAVISGA------LLPLQLDFGLSCLEQEFLVGSLL---- 55
Query: 92 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVI 151
+G ++ S G ++ +GR+ ++L NL+ G +GL A S+ L+LGR V+
Sbjct: 56 ----LGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAVV 108
Query: 152 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVL 211
G L + +Y+ E+ RG +L + GI +GIL++ L G+ W +
Sbjct: 109 GFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYAL-AGTPWGWRHM 167
Query: 212 LGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESA 271
G+ PA+LQS +L L + +E AT +D+ I E+
Sbjct: 168 FGWATAPAVLQSLSL---------LFLPAGTDETATH--------KDL---IPLQGGEAP 207
Query: 272 RMSQEK-QVTVLELFRV-SSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV---Q 326
++ + + + L+LFR + R + + L L QQL+G V Y++ IF G
Sbjct: 208 KLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGS 267
Query: 327 QPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMA 367
+ A++ G V TL ++ LV+RAGRR L + G MA
Sbjct: 268 SAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMA 308
Score = 60.5 bits (145), Expect = 4e-09
Identities = 28/98 (28%), Positives = 53/98 (54%), Gaps = 1/98 (1%)
Query: 394 ILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLG- 452
++VFV+ F G GP+ W +++E++ R A A NW +N + L F +G
Sbjct: 416 LMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGL 475
Query: 453 AYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE 490
++ F+++ + L F + VPET+G++ +I + F+
Sbjct: 476 SWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQ 513
>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
Length = 557
Score = 65.5 bits (158), Expect = 1e-10
Identities = 107/417 (25%), Positives = 180/417 (43%), Gaps = 62/417 (14%)
Query: 89 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGR 148
L++++F VG ++GSF G +RFGR+N +L V + TG + + +++ EM ++
Sbjct: 144 LTISLFFVGVLLGSFISGQLSDRFGRKN-VLFVTMGMQTGFSFLQI--FSKNFEMFVVLF 200
Query: 149 LVIGLFCGLCTGFVPMYI--GEISPTALRGAFGTLNQLGIVIGILVAQIFG---LELILG 203
+++G+ G + +V ++ EI ++R F TL G+ + FG L L
Sbjct: 201 VLVGM--GQISNYVAAFVLGTEILGKSVRIIFSTL-------GVCIFYAFGYMVLPLFAY 251
Query: 204 SEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQ-- 261
W +LL +P +L A PESPR+ LI++ + E A I+++ +
Sbjct: 252 FIRDWRMLLVALTMPGVLCVALWWFIPESPRW-LISQGRFEEAEVIIRKAAKANGIVVPS 310
Query: 262 ---DIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLS-------QQLSGINA 311
D E++D S++ Q +L+L R + R I+SI+L ++ L N
Sbjct: 311 TIFDPSELQDLSSKKQQSH--NILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNL 368
Query: 312 VFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCST 371
F A V+ P Y + LL +L R T + LGG S
Sbjct: 369 HGDIFVNCFLSAMVEVPAY---------VLAWLLLQYLPRRYSMAT--ALFLGG----SV 413
Query: 372 LMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPG-PIPWFIVAELFSQGPRPAAMAVAG 430
L+ + L+ + Y + +LV V F + + + AEL+ R + V+
Sbjct: 414 LLFMQLVPPDLY------YLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSS 467
Query: 431 CSNWTSNFLVGLLFPSAAYYLGAY---VFIIFTGFLITFLAFTFFKVPETRGRTFED 484
T++ L +L P YLGAY + I G L A +PE+ G D
Sbjct: 468 ----TASRLGSILSPYFV-YLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPD 519
>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
Length = 551
Score = 60.1 bits (144), Expect = 5e-09
Identities = 102/407 (25%), Positives = 178/407 (43%), Gaps = 44/407 (10%)
Query: 89 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGR 148
L+ ++F VG ++GSF G +RFGR+N +L + TG + + I S EM +
Sbjct: 144 LTTSLFFVGVLLGSFVSGQLSDRFGRKN-VLFATMAVQTGFSFLQIFSI--SWEMFTVLF 200
Query: 149 LVIGLFCGLCTGFVPMYI--GEISPTALRGAFGTLNQLG-IVIGILVAQIFGLELILGSE 205
+++G+ G + +V +I EI ++R F TL +G ++ +F +
Sbjct: 201 VIVGM--GQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFI----- 253
Query: 206 ELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQD--I 263
W +LL +P +L PESPR+L+ R+ E A I+Q+ +++ I
Sbjct: 254 RDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFRE-AEDIIQKAAKMNNIAVPAVI 312
Query: 264 QEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDA 323
+ +E + Q+K +L+LFR + I+S++L + + G A+ + + DA
Sbjct: 313 FDSVEELNPLKQQK-AFILDLFRTRNIAIMTIMSLLLWMLTSV-GYFALSLDAPNLHGDA 370
Query: 324 GVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTL--HMIGLGGMAFCSTLMTVSLLLKN 381
+ + A I T + LL RR + ++ GG L+ + L+ +
Sbjct: 371 YLNCFLSALIEIPAYITAWLLL-----RTLPRRYIIAAVLFWGG----GVLLFIQLVPVD 421
Query: 382 HYNGMSFVCIGAILVFVACFEIGPG-PIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLV 440
+Y F+ IG LV + F I + + AEL+ R A+ V ++ V
Sbjct: 422 YY----FLSIG--LVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTAS-----RV 470
Query: 441 GLLFPSAAYYLGAY---VFIIFTGFLITFLAFTFFKVPETRGRTFED 484
G + YLGAY + I G L + PE+ G T +
Sbjct: 471 GSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPE 517
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 58.9 bits (141), Expect = 1e-08
Identities = 53/177 (29%), Positives = 82/177 (46%), Gaps = 15/177 (8%)
Query: 81 VLLTNLWSLSV--AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIA 138
++ N W L + + +VG IGS S+G +RFGR+ +L L+ A G LM I+
Sbjct: 141 LVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMA---IS 197
Query: 139 ESVEMLILGRLVIGLF--CGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIF 196
+ +++ RL+ GL G G++ I E R G Q+ +G+LV +
Sbjct: 198 PTYTWMLIFRLIQGLVSKAGWLIGYI--LITEFVGRRYRRTVGIFYQVAYTVGLLV--LA 253
Query: 197 GLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRL 253
G+ L W L LP C PESPR+ LI++ K A RI++ +
Sbjct: 254 GVAYALPH---WRWLQFTVALPNFFFLLYYWCIPESPRW-LISQNKNAEAMRIIKHI 306
>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
Length = 556
Score = 57.4 bits (137), Expect = 3e-08
Identities = 96/419 (22%), Positives = 185/419 (44%), Gaps = 40/419 (9%)
Query: 80 EVLLTNLWSLSV--AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMG-LCK 136
+++ N W L + AI ++G + G+F++G +R+GR +++ LL+ G + G +
Sbjct: 145 DLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGR----IVIYLLSCLGVGVTGVVVA 200
Query: 137 IAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIF 196
A + + ++ R + G+F + + EI + R G + Q+ +GI++ +
Sbjct: 201 FAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIII--LP 258
Query: 197 GLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRL--W 254
G+ + + W + LP+ L PESPR+ LI RKK + A +IL+R+
Sbjct: 259 GIAYFIPN---WQGIQLAITLPSFLFLLYYWVVPESPRW-LITRKKGDKALQILRRIAKC 314
Query: 255 GTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFY 314
+ +S + E+ +S + L+L R R+ +I + + +
Sbjct: 315 NGKYLSSNYSEITVTDEEVSNP---SFLDLVRTPQMRKCTLILM-------FAWFTSAVV 364
Query: 315 YSTGIFKDAGVQQPIYAT-ISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLM 373
Y + + + +Y +GVV LL L +ER GRR L +A + L+
Sbjct: 365 YQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRR-LPFAASNIVAGVACLV 423
Query: 374 TVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAV-AGCS 432
T L + + +G + + +A FE I + + +EL+ R +++ +G
Sbjct: 424 TAFLPEGIAWLRTTVATLGRLGITMA-FE-----IVYLVNSELYPTTLRNFGVSLCSGLC 477
Query: 433 NWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRG----RTFEDITR 487
++ LLF AA +L + +I G L + +PET+G T +D+ +
Sbjct: 478 DFGGIIAPFLLFRLAAVWL--ELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEK 534
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 56.2 bits (134), Expect = 7e-08
Identities = 101/443 (22%), Positives = 177/443 (39%), Gaps = 52/443 (11%)
Query: 87 WSLSV--AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEML 144
W L + + + G + GS VG F +RFGR+ +L L+ A G LM + + +
Sbjct: 146 WKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMA---FSPNYMSM 202
Query: 145 ILGRLVIGLFC--GLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELIL 202
+L RL+ GL G+ I E + R + Q+ +G++ + GL L
Sbjct: 203 LLFRLLQGLVSKGNWMAGYT--LITEFVGSGSRRTVAIMYQMAFTVGLVA--LTGLAYAL 258
Query: 203 GSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQD 262
W L LP L C PESPR+LL ++K+ A +I+ ++Q
Sbjct: 259 PH---WRWLQLAVSLPTFLFLLYYWCVPESPRWLL-SQKRNTEAIKIMDH------IAQK 308
Query: 263 IQEMKDESARM-SQEKQVT------VLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYY 315
++ +M S E+ VT +LFR R+ I + L + ++V Y
Sbjct: 309 NGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFT------DSVLYQ 362
Query: 316 STGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGR-RTLHMIGLGGMAFCSTLMT 374
+ A + + +V ++L ++R GR + M L A C ++
Sbjct: 363 GLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIF 422
Query: 375 VSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNW 434
+S L H+ + +C+G + + +A I + AEL+ R + V CS+
Sbjct: 423 ISPDL--HWLNIIIMCVGRMGITIAIQMI------CLVNAELYPTFVRNLGVMV--CSSL 472
Query: 435 TSNFLVGLLFPSAAYYL----GAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE 490
+ G++ P + L A I+F + T +PET+G + + E
Sbjct: 473 CD--IGGIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLL-LPETKGVALPETMKDAE 529
Query: 491 GQAHGADRSGKDGVMGMNSIEPA 513
A + + + EP+
Sbjct: 530 NLGRKAKPKENTIYLKVQTSEPS 552
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 55.8 bits (133), Expect = 9e-08
Identities = 78/325 (24%), Positives = 136/325 (41%), Gaps = 37/325 (11%)
Query: 87 WSLSV--AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEML 144
W L + + + G + GS VG F +RFGR+ +L L+ A G LM + + +
Sbjct: 146 WKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMA---FSPNYMSM 202
Query: 145 ILGRLVIGLFC--GLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELIL 202
+L RL+ GL G+ I E + R + Q+ +G++ + GL L
Sbjct: 203 LLFRLLQGLVSKGNWMAGYT--LITEFVGSGSRRTVAIMYQMAFTVGLVA--LTGLAYAL 258
Query: 203 GSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQD 262
W L LP L C PESPR+LL ++K+ A +I+ ++Q
Sbjct: 259 PH---WRWLQLAVSLPTFLFLLYYWCVPESPRWLL-SQKRNTEAIKIMDH------IAQK 308
Query: 263 IQEMKDESARM-SQEKQVT------VLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYY 315
++ +M S E+ VT +LFR R+ I + L + ++V Y
Sbjct: 309 NGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFT------DSVLYQ 362
Query: 316 STGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGR-RTLHMIGLGGMAFCSTLMT 374
+ A + + +V ++L ++R GR + M L A C ++
Sbjct: 363 GLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIF 422
Query: 375 VSLLLKNHYNGMSFVCIGAILVFVA 399
+S L H+ + +C+G + + +A
Sbjct: 423 ISPDL--HWLNIIIMCVGRMGITIA 445
>gi|8923870 solute carrier family 22 member 11 [Homo sapiens]
Length = 550
Score = 48.9 bits (115), Expect = 1e-05
Identities = 96/435 (22%), Positives = 161/435 (37%), Gaps = 45/435 (10%)
Query: 89 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGR 148
LS +IF G ++GSF GL RFGR+ + L A + G I ++ G
Sbjct: 144 LSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLA----VAGTSTIFAPTFVIYCGL 199
Query: 149 LVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELW 208
+ F G+ F+ + T T+ +G A + GL L W
Sbjct: 200 RFVAAF-GMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRD---W 255
Query: 209 PVLLGFTILPAILQSAALPCCPESPRFLLINRKKEE--NATRILQRLWGTQDVSQDIQEM 266
L +P S PES R+L+I K ++ R + R+ G ++ E+
Sbjct: 256 RTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEV 315
Query: 267 KDESAR---MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDA 323
S + S ++ +VL+LF V R +V+ S +S VF + + +D
Sbjct: 316 LMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQS-LGRDI 374
Query: 324 GVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHY 383
+ Q ++ G V+ + + L+ GRRT I G A + ++L+
Sbjct: 375 FLLQALF-----GAVDFLGRATTALLLSFLGRRT---IQAGSQAMAGLAILANMLVPQDL 426
Query: 384 NGMSFV-------CIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTS 436
+ V C G L + ++ AELF P P M G +
Sbjct: 427 QTLRVVFAVLGKGCFGISLTCLTIYK-----------AELF---PTPVRMTADGILHTVG 472
Query: 437 NF--LVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAH 494
++G L + L +++ I F +PET+G D + E Q
Sbjct: 473 RLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKS 532
Query: 495 GADRSGKDGVMGMNS 509
A + + + + S
Sbjct: 533 TAAQGNRQEAVTVES 547
>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
Length = 727
Score = 45.8 bits (107), Expect = 9e-05
Identities = 54/209 (25%), Positives = 84/209 (40%), Gaps = 17/209 (8%)
Query: 92 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVI 151
+I +G M+G+F G ++ GR+ S+LI + G L + + RL+
Sbjct: 195 SIVYLGMMVGAFFWGGLADKVGRKQSLLIC---MSVNGFFAFLSSFVQGYGFFLFCRLLS 251
Query: 152 GLFCGLCTGFVPMYIGEISPTALRGA-FGTLNQLGIVIGILVAQI-------FGLELILG 203
G G V Y E+ RG L ++ GI + + +G +G
Sbjct: 252 GFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMG 311
Query: 204 SE---ELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVS 260
S W V + LP + AL PESPRFLL K +E A IL+ + T +
Sbjct: 312 SAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDE-AWMILKLIHDTNMRA 370
Query: 261 QDIQEMKDESARMSQEKQVTVLELFRVSS 289
+ E ++ KQ+ EL + S
Sbjct: 371 RGQPEKVFTVNKIKTPKQID--ELIEIES 397
>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
sapiens]
Length = 548
Score = 45.4 bits (106), Expect = 1e-04
Identities = 101/409 (24%), Positives = 157/409 (38%), Gaps = 45/409 (11%)
Query: 94 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAE-SVEMLILGRLVIG 152
F G ++G+ + G +RFGRR +L+ A ++GL A S M + R + G
Sbjct: 151 FFAGVLVGAVAFGYLSDRFGRRRLLLV----AYVSTLVLGLASAASVSYVMFAITRTLTG 206
Query: 153 -LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVL 211
G +P+ + E R G L+ G+++ + G + W L
Sbjct: 207 SALAGFTIIVMPLEL-EWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLI-----RDWRWL 260
Query: 212 LGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQ--RLWGTQDVSQDIQEMKDE 269
L LP +L PES R+LL +E +L RL G + V +D +
Sbjct: 261 LLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNG-RPVCEDSFSQEAV 319
Query: 270 SARMSQEKQV---TVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKD-AGV 325
S + E+ V + L+LFR R + +V+ G+N +Y G+ D +G+
Sbjct: 320 SKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWF-----GVNFSYY---GLSLDVSGL 371
Query: 326 QQPIYAT-ISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYN 384
+Y T + G V LL V AGRR L G A LL+ +
Sbjct: 372 GLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALA---FGTRLLVSSDMK 428
Query: 385 GMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLF 444
S V + V F + +EL+ R M + L G L
Sbjct: 429 SWSTV----LAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTA----LVGRLGGSLA 480
Query: 445 PSAAYYLGAYVFI--IFTGFLITFLAFTFFKVPETR----GRTFEDITR 487
P AA G ++ + + G + A T +PETR T +D+ R
Sbjct: 481 PLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVER 529
>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
sapiens]
Length = 546
Score = 45.4 bits (106), Expect = 1e-04
Identities = 101/409 (24%), Positives = 157/409 (38%), Gaps = 45/409 (11%)
Query: 94 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAE-SVEMLILGRLVIG 152
F G ++G+ + G +RFGRR +L+ A ++GL A S M + R + G
Sbjct: 149 FFAGVLVGAVAFGYLSDRFGRRRLLLV----AYVSTLVLGLASAASVSYVMFAITRTLTG 204
Query: 153 -LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVL 211
G +P+ + E R G L+ G+++ + G + W L
Sbjct: 205 SALAGFTIIVMPLEL-EWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLI-----RDWRWL 258
Query: 212 LGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQ--RLWGTQDVSQDIQEMKDE 269
L LP +L PES R+LL +E +L RL G + V +D +
Sbjct: 259 LLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNG-RPVCEDSFSQEAV 317
Query: 270 SARMSQEKQV---TVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKD-AGV 325
S + E+ V + L+LFR R + +V+ G+N +Y G+ D +G+
Sbjct: 318 SKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWF-----GVNFSYY---GLSLDVSGL 369
Query: 326 QQPIYAT-ISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYN 384
+Y T + G V LL V AGRR L G A LL+ +
Sbjct: 370 GLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALA---FGTRLLVSSDMK 426
Query: 385 GMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLF 444
S V + V F + +EL+ R M + L G L
Sbjct: 427 SWSTV----LAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTA----LVGRLGGSLA 478
Query: 445 PSAAYYLGAYVFI--IFTGFLITFLAFTFFKVPETR----GRTFEDITR 487
P AA G ++ + + G + A T +PETR T +D+ R
Sbjct: 479 PLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVER 527
>gi|31542327 solute carrier family 22, member 16 [Homo sapiens]
Length = 577
Score = 44.7 bits (104), Expect = 2e-04
Identities = 90/412 (21%), Positives = 159/412 (38%), Gaps = 65/412 (15%)
Query: 93 IFSVGGMIGSFSVGLFVNRFGRR-------NSMLIVNLLAATGGCLMGLCKIAESVEMLI 145
+F G ++GS + G F +R GRR +SM + + AA + M+
Sbjct: 160 LFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVA 219
Query: 146 LGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSE 205
G LV+G +V +IG S T + +G L+ + G ++ +
Sbjct: 220 SGYLVVGFV------YVMEFIGMKSRTWASVHLHSF----FAVGTLLVALTG--YLVRTW 267
Query: 206 ELWPVLLGFTILPAILQSAALPCC---PESPRFLLINRKKEENATRILQRL--WG----- 255
L+ ++L +P IL CC PE+P F L++ + E A +I+ + W
Sbjct: 268 WLYQMILSTVTVPFIL------CCWVLPETP-FWLLSEGRYEEAQKIVDIMAKWNRASSC 320
Query: 256 --TQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVF 313
++ +S D+Q S Q+ ++ L + S ++ + + ++ +G +
Sbjct: 321 KLSELLSLDLQGPVSNSPTEVQKHNLSYL-FYNWSITKRTLTVWLI-----WFTGSLGFY 374
Query: 314 YYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLM 373
+S G GVV +++ GRRT+ L FCS L
Sbjct: 375 SFSLNSVNLGG--NEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTV----LAYSLFCSALA 428
Query: 374 --TVSLLLKNHYNGMSFVCIGAILVFVACFEIGPG-PIPWFIVAELFSQGPRPAAMAVAG 430
V ++ + HY +G + V F IG + + AEL+ P G
Sbjct: 429 CGVVMVIPQKHY------ILGVVTAMVGKFAIGAAFGLIYLYTAELY---PTIVRSLAVG 479
Query: 431 CSNWTSNFLVGLLFPSAAYYLGAYVFI--IFTGFLITFLAFTFFKVPETRGR 480
+ L +L P + ++FI +F G + K+PET G+
Sbjct: 480 SGSMVCR-LASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGK 530
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.141 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,852,382
Number of Sequences: 37866
Number of extensions: 748183
Number of successful extensions: 2496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2390
Number of HSP's gapped (non-prelim): 77
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.