Guide to the Human Genome
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Search of human proteins with 116063536

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116063536 coenzyme Q5 homolog, methyltransferase [Homo
sapiens]
         (327 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116063536 coenzyme Q5 homolog, methyltransferase [Homo sapiens]    667   0.0  
gi|40018642 hypothetical protein LOC79133 isoform 1 [Homo sapiens]     41   0.002
gi|12758125 ribosomal RNA processing 8, methyltransferase, homol...    36   0.053
gi|42542403 CGI-01 protein isoform 1 [Homo sapiens]                    33   0.26 
gi|223005862 echinoderm microtubule associated protein like 6 [H...    32   0.59 
gi|153945707 endothelin converting enzyme 2 isoform C [Homo sapi...    32   0.59 
gi|42542405 CGI-01 protein isoform 2 [Homo sapiens]                    32   0.77 
gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo s...    31   1.3  
gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo s...    31   1.3  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    30   2.9  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    30   2.9  
gi|44955929 calmodulin regulated spectrin-associated protein 1-l...    30   3.8  
gi|210032790 hypothetical protein LOC27146 [Homo sapiens]              29   6.5  
gi|193794843 BEN domain containing 2 [Homo sapiens]                    29   6.5  
gi|169203189 PREDICTED: hypothetical protein LOC338667 [Homo sap...    28   8.5  
gi|169203683 PREDICTED: hypothetical protein LOC338667 [Homo sap...    28   8.5  
gi|169202109 PREDICTED: hypothetical protein LOC338667 [Homo sap...    28   8.5  

>gi|116063536 coenzyme Q5 homolog, methyltransferase [Homo sapiens]
          Length = 327

 Score =  667 bits (1720), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MAAPGSCALWSYCGRGWSRAMRGCQLLGLRSSWPGDLLSARLLSQEKRAAETHFGFETVS 60
           MAAPGSCALWSYCGRGWSRAMRGCQLLGLRSSWPGDLLSARLLSQEKRAAETHFGFETVS
Sbjct: 1   MAAPGSCALWSYCGRGWSRAMRGCQLLGLRSSWPGDLLSARLLSQEKRAAETHFGFETVS 60

Query: 61  EEEKGGKVYQVFESVAKKYDVMNDMMSLGIHRVWKDLLLWKMHPLPGTQLLDVAGGTGDI 120
           EEEKGGKVYQVFESVAKKYDVMNDMMSLGIHRVWKDLLLWKMHPLPGTQLLDVAGGTGDI
Sbjct: 61  EEEKGGKVYQVFESVAKKYDVMNDMMSLGIHRVWKDLLLWKMHPLPGTQLLDVAGGTGDI 120

Query: 121 AFRFLNYVQSQHQRKQKRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVVCDINKEMLKVG 180
           AFRFLNYVQSQHQRKQKRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVVCDINKEMLKVG
Sbjct: 121 AFRFLNYVQSQHQRKQKRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVVCDINKEMLKVG 180

Query: 181 KQKALAQGYRAGLAWVLGDAEELPFDDDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGG 240
           KQKALAQGYRAGLAWVLGDAEELPFDDDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGG
Sbjct: 181 KQKALAQGYRAGLAWVLGDAEELPFDDDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGG 240

Query: 241 RFLCLEFSQVNNPLISRLYDLYSFQVIPVLGEVIAGDWKSYQYLVESIRRFPSQEEFKDM 300
           RFLCLEFSQVNNPLISRLYDLYSFQVIPVLGEVIAGDWKSYQYLVESIRRFPSQEEFKDM
Sbjct: 241 RFLCLEFSQVNNPLISRLYDLYSFQVIPVLGEVIAGDWKSYQYLVESIRRFPSQEEFKDM 300

Query: 301 IEDAGFHKVTYESLTSGIVAIHSGFKL 327
           IEDAGFHKVTYESLTSGIVAIHSGFKL
Sbjct: 301 IEDAGFHKVTYESLTSGIVAIHSGFKL 327


>gi|40018642 hypothetical protein LOC79133 isoform 1 [Homo sapiens]
          Length = 345

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 18/48 (37%), Positives = 29/48 (60%)

Query: 196 VLGDAEELPFDDDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGGRFL 243
           VL D E LPF ++ FD+   +  +  V  + +AL++ H +LKP G F+
Sbjct: 138 VLADEEFLPFKENTFDLVVSSLSLHWVNDLPRALEQIHYILKPDGVFI 185


>gi|12758125 ribosomal RNA processing 8, methyltransferase, homolog
           [Homo sapiens]
          Length = 456

 Score = 35.8 bits (81), Expect = 0.053
 Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 8/66 (12%)

Query: 199 DAEELPFDDDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGGRFLCLEFSQVNNPLISRL 258
           D  ++P +D+  D+      +   T+I   L+EA+RVLKPGG     E S       SR 
Sbjct: 346 DMAQVPLEDESVDVAVFCLSLMG-TNIRDFLEEANRVLKPGGLLKVAEVS-------SRF 397

Query: 259 YDLYSF 264
            D+ +F
Sbjct: 398 EDVRTF 403


>gi|42542403 CGI-01 protein isoform 1 [Homo sapiens]
          Length = 699

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 23/99 (23%), Positives = 48/99 (48%), Gaps = 11/99 (11%)

Query: 162 LGGSRVVVCDINKEMLKVGKQKALAQGYRAGLAWVLGDAEELPFDDDKFDIYTIAFGI-- 219
           +G   +V  DI++ ++K  K+    +  R  ++++  D  ++ F D  F +      +  
Sbjct: 69  VGYRDIVNIDISEVVIKQMKECNATR--RPQMSFLKMDMTQMEFPDASFQVVLDKGTLDA 126

Query: 220 -------RNVTHIDQALQEAHRVLKPGGRFLCLEFSQVN 251
                  + +  +D+ L E  RVL+ GGR+LC+  +Q +
Sbjct: 127 VLTDEEEKTLQQVDRMLAEVGRVLQVGGRYLCISLAQAH 165


>gi|223005862 echinoderm microtubule associated protein like 6 [Homo
            sapiens]
          Length = 1958

 Score = 32.3 bits (72), Expect = 0.59
 Identities = 47/168 (27%), Positives = 63/168 (37%), Gaps = 29/168 (17%)

Query: 161  SLGGSRVVVCDINKEMLKV---GKQKALAQGYRAGLAWVLGDAEELPFDDDKFDIYTIAF 217
            +LG   ++V   N E+L++   G    L QG+  G  W L     LP      D  T+  
Sbjct: 965  TLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPICATVSDDKTLRI 1024

Query: 218  GIRNVTHIDQALQEAHRVLKPGGRFLCLEFSQVNNPLISRLYDLYSFQVIPVLGEVIAGD 277
               +  H   A+    R LK GGR  C  FS     L   L D  SF V+          
Sbjct: 1025 WELSAQHRMLAV----RKLKKGGR--CCAFSPDGKALAVGLND-GSFLVVN--------- 1068

Query: 278  WKSYQYLVESIRRFPSQEEFKDMIEDAGFHKVTYESLTSGIVAIHSGF 325
                    +++    S    K+MI D  F K T + L    VA H  F
Sbjct: 1069 -------ADTVEDMVSFHHRKEMISDIKFSKDTGKYLA---VASHDNF 1106


>gi|153945707 endothelin converting enzyme 2 isoform C [Homo
           sapiens]
          Length = 255

 Score = 32.3 bits (72), Expect = 0.59
 Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 15/68 (22%)

Query: 193 LAWVLGDAEELPFDDDKFDIY-------TIAFGIRN--------VTHIDQALQEAHRVLK 237
           L W   D  +L F    FD+         +  G R+        V  +DQ L E  RVL 
Sbjct: 107 LRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLV 166

Query: 238 PGGRFLCL 245
           PGGRF+ +
Sbjct: 167 PGGRFISM 174


>gi|42542405 CGI-01 protein isoform 2 [Homo sapiens]
          Length = 613

 Score = 32.0 bits (71), Expect = 0.77
 Identities = 12/32 (37%), Positives = 21/32 (65%)

Query: 220 RNVTHIDQALQEAHRVLKPGGRFLCLEFSQVN 251
           + +  +D+ L E  RVL+ GGR+LC+  +Q +
Sbjct: 48  KTLQQVDRMLAEVGRVLQVGGRYLCISLAQAH 79


>gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo
           sapiens]
          Length = 1075

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 17/39 (43%), Positives = 23/39 (58%)

Query: 137 KRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVVCDINKE 175
           K+Q  A  N   EE+A+ Y+N ED L  S V   D+N+E
Sbjct: 542 KKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEE 580


>gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo
           sapiens]
          Length = 1133

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 17/39 (43%), Positives = 23/39 (58%)

Query: 137 KRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVVCDINKE 175
           K+Q  A  N   EE+A+ Y+N ED L  S V   D+N+E
Sbjct: 600 KKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEE 638


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 38/148 (25%), Positives = 63/148 (42%), Gaps = 16/148 (10%)

Query: 23   GCQLLGLRSSWPGDLLSARLLSQEKRAAETHFGFETVSEEEKG--------GKVYQVFES 74
            GCQ   L S +   LL  ++L Q K   E     +++ E E          G  ++ F++
Sbjct: 3661 GCQATQLTSRYQALLL--QVLEQIKFLEEE---IQSLEESESSLSSYSDWYGSTHKNFKN 3715

Query: 75   VAKKYDVMNDMMSLGIHRVWKDLLLWKMHPLPGTQLLDVAGGTGDIAFRFLNYVQSQHQR 134
            VA K D ++ +M +G      ++LL  M    G  LL  A   G+ A ++L   +++  R
Sbjct: 3716 VATKIDKVDTVM-MGKKLKTLEVLLKDMEK--GHSLLKSAREKGERAVKYLEEGEAERLR 3772

Query: 135  KQKRQLRAQQNLSWEEIAKEYQNEEDSL 162
            K+      Q       + KE+   E  L
Sbjct: 3773 KEIHDHMEQLKELTSTVRKEHMTLEKGL 3800


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 38/148 (25%), Positives = 63/148 (42%), Gaps = 16/148 (10%)

Query: 23   GCQLLGLRSSWPGDLLSARLLSQEKRAAETHFGFETVSEEEKG--------GKVYQVFES 74
            GCQ   L S +   LL  ++L Q K   E     +++ E E          G  ++ F++
Sbjct: 3676 GCQATQLTSRYQALLL--QVLEQIKFLEEE---IQSLEESESSLSSYSDWYGSTHKNFKN 3730

Query: 75   VAKKYDVMNDMMSLGIHRVWKDLLLWKMHPLPGTQLLDVAGGTGDIAFRFLNYVQSQHQR 134
            VA K D ++ +M +G      ++LL  M    G  LL  A   G+ A ++L   +++  R
Sbjct: 3731 VATKIDKVDTVM-MGKKLKTLEVLLKDMEK--GHSLLKSAREKGERAVKYLEEGEAERLR 3787

Query: 135  KQKRQLRAQQNLSWEEIAKEYQNEEDSL 162
            K+      Q       + KE+   E  L
Sbjct: 3788 KEIHDHMEQLKELTSTVRKEHMTLEKGL 3815


>gi|44955929 calmodulin regulated spectrin-associated protein 1-like
           1 [Homo sapiens]
          Length = 1478

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 8/70 (11%)

Query: 175 EMLKVGKQKALAQGYRAGLAWVLGDAEELPFDDDKFDIYTIAF---GIRNVTHIDQALQE 231
           EM+ + K  A AQ Y A        A +LP+D +   +Y I      ++++   +Q L+E
Sbjct: 150 EMVSIEKVIACAQQYSAFF-----QATDLPYDIEDAVMYWINKVNEHLKDIMEQEQKLKE 204

Query: 232 AHRVLKPGGR 241
            H V  PGG+
Sbjct: 205 HHTVEAPGGQ 214


>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
          Length = 1060

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 16/77 (20%), Positives = 39/77 (50%)

Query: 111 LDVAGGTGDIAFRFLNYVQSQHQRKQKRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVVC 170
           L +   T  +  + L     Q  ++++ +++AQQ L  E + +E   ++ +  G +  + 
Sbjct: 693 LQIQHQTHRLELQALEEKARQELQEERERMQAQQALLLESLRQELSEQQAACSGHQKDLE 752

Query: 171 DINKEMLKVGKQKALAQ 187
            +  E+  +G+Q+A +Q
Sbjct: 753 ALQAELRALGRQQASSQ 769


>gi|193794843 BEN domain containing 2 [Homo sapiens]
          Length = 799

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 15/37 (40%), Positives = 18/37 (48%)

Query: 10  WSYCGRGWSRAMRGCQLLGLRSSWPGDLLSARLLSQE 46
           WSY GR W      C +L L  +     LSAR L Q+
Sbjct: 660 WSYFGRPWRNIRMPCSVLTLAKTKSCASLSARYLIQK 696


>gi|169203189 PREDICTED: hypothetical protein LOC338667 [Homo
           sapiens]
          Length = 859

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 4/39 (10%)

Query: 1   MAAPGSCA--LWSYCGRG--WSRAMRGCQLLGLRSSWPG 35
           +A P  C   LW   GR   WS A  G Q + L   WPG
Sbjct: 456 LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPG 494


>gi|169203683 PREDICTED: hypothetical protein LOC338667 [Homo
           sapiens]
          Length = 859

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 4/39 (10%)

Query: 1   MAAPGSCA--LWSYCGRG--WSRAMRGCQLLGLRSSWPG 35
           +A P  C   LW   GR   WS A  G Q + L   WPG
Sbjct: 456 LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPG 494


>gi|169202109 PREDICTED: hypothetical protein LOC338667 [Homo
           sapiens]
          Length = 859

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 4/39 (10%)

Query: 1   MAAPGSCA--LWSYCGRG--WSRAMRGCQLLGLRSSWPG 35
           +A P  C   LW   GR   WS A  G Q + L   WPG
Sbjct: 456 LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPG 494


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,883,927
Number of Sequences: 37866
Number of extensions: 540178
Number of successful extensions: 1474
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1465
Number of HSP's gapped (non-prelim): 17
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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