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Search of human proteins with 116008194
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116008194 myosin light chain kinase isoform 3A [Homo
sapiens]
(1863 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 3759 0.0
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 3736 0.0
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 3437 0.0
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 3413 0.0
gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens] 313 1e-84
gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens] 306 9e-83
gi|110349719 titin isoform N2-A [Homo sapiens] 295 3e-79
gi|110349717 titin isoform novex-2 [Homo sapiens] 295 3e-79
gi|110349713 titin isoform novex-1 [Homo sapiens] 295 3e-79
gi|110349715 titin isoform N2-B [Homo sapiens] 295 3e-79
gi|146219832 myosin light chain kinase 3 [Homo sapiens] 236 2e-61
gi|167466233 myosin light chain kinase family, member 4 [Homo sa... 221 7e-57
gi|14993776 skeletal myosin light chain kinase [Homo sapiens] 220 1e-56
gi|89363047 death-associated protein kinase 1 [Homo sapiens] 200 9e-51
gi|4557511 death-associated protein kinase 3 [Homo sapiens] 191 6e-48
gi|14670383 death-associated kinase 2 [Homo sapiens] 189 3e-47
gi|157785645 SPEG complex locus [Homo sapiens] 186 2e-46
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens] 185 4e-46
gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens] 185 4e-46
gi|118572606 hemicentin 1 [Homo sapiens] 179 2e-44
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 171 5e-42
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 171 5e-42
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 171 5e-42
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 158 5e-38
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 158 5e-38
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 154 6e-37
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 154 6e-37
gi|109150416 peroxidasin [Homo sapiens] 152 2e-36
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 151 7e-36
gi|4758194 serine/threonine kinase 17B [Homo sapiens] 147 1e-34
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 3759 bits (9749), Expect = 0.0
Identities = 1863/1863 (100%), Positives = 1863/1863 (100%)
Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG
Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP
Sbjct: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT
Sbjct: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
Query: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV
Sbjct: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
Sbjct: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ
Sbjct: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV
Sbjct: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
Query: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
Sbjct: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
Query: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
Sbjct: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
Query: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
Sbjct: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG
Sbjct: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT
Sbjct: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
Sbjct: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
Sbjct: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
Sbjct: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE
Sbjct: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
Sbjct: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA
Sbjct: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
Sbjct: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
Sbjct: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL 1680
LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL
Sbjct: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL 1680
Query: 1681 SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1740
SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED
Sbjct: 1681 SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1740
Query: 1741 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1800
VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE
Sbjct: 1741 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1800
Query: 1801 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE
Sbjct: 1801 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
Query: 1861 EEE 1863
EEE
Sbjct: 1861 EEE 1863
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 3736 bits (9687), Expect = 0.0
Identities = 1863/1914 (97%), Positives = 1863/1914 (97%), Gaps = 51/1914 (2%)
Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG
Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP
Sbjct: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT
Sbjct: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
Query: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV
Sbjct: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
Sbjct: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ
Sbjct: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV
Sbjct: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
Query: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
Sbjct: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
Query: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
Sbjct: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
Query: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
Sbjct: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG
Sbjct: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT
Sbjct: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
Sbjct: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
Sbjct: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
Sbjct: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE
Sbjct: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
Sbjct: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA
Sbjct: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
Sbjct: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
Sbjct: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL-------------------------- 1654
LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL
Sbjct: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1680
Query: 1655 -------------------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1689
NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM
Sbjct: 1681 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1740
Query: 1690 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1749
ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV
Sbjct: 1741 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1800
Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809
AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD
Sbjct: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860
Query: 1810 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1861 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914
>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
Length = 1794
Score = 3437 bits (8911), Expect = 0.0
Identities = 1739/1863 (93%), Positives = 1749/1863 (93%), Gaps = 69/1863 (3%)
Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA
Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA-- 358
Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
PGLG V+S + R R + FP +
Sbjct: 359 --------------------------PGLG---VLSPSGEERKRPAPPRPATFPTRQPGL 389
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
SQ+V ++ R + G F E P S EV E+ + C
Sbjct: 390 GSQDVV-SKAANRRIPMEGQRDSAFPKF-ESKPQ-----SQEVKENQTVKFRC------- 435
Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
E LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT
Sbjct: 436 ------------------------EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 471
Query: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV
Sbjct: 472 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
Sbjct: 532 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 591
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ
Sbjct: 592 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 651
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV
Sbjct: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG
Sbjct: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 771
Query: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
Sbjct: 772 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831
Query: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
Sbjct: 832 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 891
Query: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
Sbjct: 892 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 951
Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG
Sbjct: 952 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1011
Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT
Sbjct: 1012 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1071
Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
Sbjct: 1072 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1131
Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
Sbjct: 1132 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1191
Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
Sbjct: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE
Sbjct: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
Sbjct: 1312 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA
Sbjct: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1431
Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
Sbjct: 1432 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1491
Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
Sbjct: 1492 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1551
Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL 1680
LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL
Sbjct: 1552 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL 1611
Query: 1681 SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1740
SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED
Sbjct: 1612 SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1671
Query: 1741 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1800
VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE
Sbjct: 1672 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1731
Query: 1801 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE
Sbjct: 1732 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1791
Query: 1861 EEE 1863
EEE
Sbjct: 1792 EEE 1794
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 3413 bits (8849), Expect = 0.0
Identities = 1739/1914 (90%), Positives = 1749/1914 (91%), Gaps = 120/1914 (6%)
Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA
Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA-- 358
Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
PGLG V+S + R R + FP +
Sbjct: 359 --------------------------PGLG---VLSPSGEERKRPAPPRPATFPTRQPGL 389
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
SQ+V ++ R + G F E P S EV E+ + C
Sbjct: 390 GSQDVV-SKAANRRIPMEGQRDSAFPKF-ESKPQ-----SQEVKENQTVKFRC------- 435
Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
E LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT
Sbjct: 436 ------------------------EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 471
Query: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV
Sbjct: 472 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
Sbjct: 532 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 591
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ
Sbjct: 592 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 651
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV
Sbjct: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG
Sbjct: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 771
Query: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
Sbjct: 772 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831
Query: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
Sbjct: 832 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 891
Query: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
Sbjct: 892 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 951
Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG
Sbjct: 952 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1011
Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT
Sbjct: 1012 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1071
Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
Sbjct: 1072 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1131
Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
Sbjct: 1132 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1191
Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
Sbjct: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE
Sbjct: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
Sbjct: 1312 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA
Sbjct: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1431
Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
Sbjct: 1432 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1491
Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
Sbjct: 1492 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1551
Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL-------------------------- 1654
LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL
Sbjct: 1552 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1611
Query: 1655 -------------------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1689
NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM
Sbjct: 1612 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1671
Query: 1690 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1749
ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV
Sbjct: 1672 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1731
Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809
AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD
Sbjct: 1732 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1791
Query: 1810 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1792 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1845
>gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens]
Length = 154
Score = 313 bits (802), Expect = 1e-84
Identities = 154/154 (100%), Positives = 154/154 (100%)
Query: 1710 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1769
MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60
Query: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 61 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
Query: 1830 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 121 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
Score = 71.6 bits (174), Expect = 7e-12
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
I V +D KYTC+A N G T EL VE
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
Score = 68.6 bits (166), Expect = 6e-11
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 2/119 (1%)
Query: 602 EKKSSRKSEYLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
E + +L VA KP P F + + DL+V++GS ++ G P PEV+W +
Sbjct: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
Query: 661 NEIQESEDFHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718
I+ES F + SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 145
Score = 62.0 bits (149), Expect = 5e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
F E +P + P F+ + + V EG RF CKI G P P+V W K + ++
Sbjct: 36 FLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 91
Query: 204 SARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 92 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
Score = 60.5 bits (145), Expect = 2e-08
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 567
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 58.5 bits (140), Expect = 6e-08
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 381 TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
T P L S++ VS+A + E + P F + EV E +F C++ G
Sbjct: 18 TSPLNAEKLESEEDVSQAFLEAVAEE--KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 75
Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
P PEV WF + +R Y++ G+ L + D Y+C A N+ G+ +C+
Sbjct: 76 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 135
Query: 501 TLQVERL 507
L VE +
Sbjct: 136 ELIVETM 142
Score = 52.4 bits (124), Expect = 4e-06
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1150
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
Score = 45.4 bits (106), Expect = 5e-04
Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 2/124 (1%)
Query: 690 TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 749
T E S +V + V E +P+F R + G + C I G P
Sbjct: 18 TSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD 77
Query: 750 PTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
P V W +D +++ +++ HF++ +ED +L++ V +Y N +GE +C
Sbjct: 78 PEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
Query: 809 LMLQ 812
L+++
Sbjct: 137 LIVE 140
Score = 32.7 bits (73), Expect = 3.4
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
Query: 1293 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1327
+ I++ + CG YT N LG L V
Sbjct: 104 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 139
>gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens]
Length = 153
Score = 306 bits (785), Expect = 9e-83
Identities = 153/154 (99%), Positives = 153/154 (99%), Gaps = 1/154 (0%)
Query: 1710 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1769
MAMISGLSGRKSSTGSPTSPLNAEKLESE DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 59
Query: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 60 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 119
Query: 1830 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 120 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
Score = 71.6 bits (174), Expect = 7e-12
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
I V +D KYTC+A N G T EL VE
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
Score = 67.8 bits (164), Expect = 1e-10
Identities = 39/110 (35%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
Query: 611 YLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
+L VA KP P F + + DL+V++GS ++ G P PEV+W + I+ES F
Sbjct: 35 FLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94
Query: 670 HFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718
+ SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 144
Score = 63.5 bits (153), Expect = 2e-09
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 5/119 (4%)
Query: 137 SKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
S+ + F E +P + P F+ + + V EG RF CKI G P P+V W K
Sbjct: 28 SEDVSQAFLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
Query: 197 GNVPLQPSARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
+ ++ S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
Score = 60.5 bits (145), Expect = 2e-08
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 567
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 56.6 bits (135), Expect = 2e-07
Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
Query: 381 TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
T P L S+DV S+A + E + P F + EV E +F C++ G
Sbjct: 18 TSPLNAEKLESEDV-SQAFLEAVAEE--KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 74
Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
P PEV WF + +R Y++ G+ L + D Y+C A N+ G+ +C+
Sbjct: 75 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 134
Query: 501 TLQVERL 507
L VE +
Sbjct: 135 ELIVETM 141
Score = 52.4 bits (124), Expect = 4e-06
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1150
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 713 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
++PH +P+F R + G + C I G P P V W +D +++ +++ HF++
Sbjct: 42 EKPH--VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDY 98
Query: 773 NED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
+ED +L++ V +Y N +GE +C L+++
Sbjct: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
Score = 32.7 bits (73), Expect = 3.4
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
Query: 1293 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1327
+ I++ + CG YT N LG L V
Sbjct: 103 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 138
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 295 bits (755), Expect = 3e-79
Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154
AP FK++L++++V L C+V+ P + W GK + K+ I +G
Sbjct: 30927 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 30986
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
+ I +D +Y+ A N G + + V+
Sbjct: 30987 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 31020
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
P K +P + +R GE V + +G TW K
Sbjct: 31021 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 31064
Query: 1275 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
+ I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP
Sbjct: 31065 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 31124
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393
P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V +
Sbjct: 31125 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 31183
Query: 1394 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453
L Y+FRV A N +G S+PS+ SE T E + E D+ EV +
Sbjct: 31184 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 31240
Query: 1454 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513
++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+
Sbjct: 31241 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 31299
Query: 1514 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573
N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E +
Sbjct: 31300 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 31359
Query: 1574 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633
+++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV
Sbjct: 31360 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 31419
Query: 1634 NYEPIGYATDMWSIGVICYIL--------------------------------------- 1654
++ + ATDMWS+G + Y+L
Sbjct: 31420 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 31479
Query: 1655 ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1702
+R+ ++ LQHPWL + + + K + + ++Y +K N V
Sbjct: 31480 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 31538
Query: 1703 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1762
+ R+S I +S G + + +E VS + AV EE HVK
Sbjct: 31539 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 31586
Query: 1763 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
+ CKIE Y +V W+ + + S ++I Y EDG L + D+
Sbjct: 31587 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 31631
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
DD Y CK VN GE + AEL V+ + E
Sbjct: 31632 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 31663
Score = 217 bits (553), Expect = 7e-56
Identities = 286/1264 (22%), Positives = 491/1264 (38%), Gaps = 198/1264 (15%)
Query: 31 EAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
+APA F+ + I++G EG G P VTW +NG +T R C I T
Sbjct: 7865 KAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQR----CNITTTE 7920
Query: 90 SLVIHAVHE---EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
I + ED G+Y C N SG + ++ +
Sbjct: 7921 KSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE--------------------- 7959
Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
PP F +L V V G C++ G P+ V+W KG+ L+P+
Sbjct: 7960 -------------PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTT 8006
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKA 266
+ +N + L + V+ +D G Y C N G+ S S L++Q SF R+ +
Sbjct: 8007 YKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE-QKLPPSFSRQLR- 8064
Query: 267 TNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCK 326
DV++ V + + + E + S W + +P K
Sbjct: 8065 ---DVQETVGLPVVFDCAISGSEPISVS-------------WYKDGKP----------LK 8098
Query: 327 DSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 386
DSP QT L T++ + R S +G+ P
Sbjct: 8099 DSPNV--QTSFLDNTATLNIFKTDR-------------SLAGQYSCTATNP--------- 8134
Query: 387 PGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVA 446
+GS + ++ R I EG+ P F+ + + ++ F C V+G +V+
Sbjct: 8135 --IGS----ASSSARLILTEGKNP---PFFDIRLAPVDAVVGESADFECHVTGTQPIKVS 8185
Query: 447 WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-E 505
W + +R G ++ S +L +LK DSG Y+C A N G+ SC+ L + E
Sbjct: 8186 WAKDSREIR-SGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKE 8244
Query: 506 RLAVMEVAPSFSSVLKDCAV-IEGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTC 561
RL + PSF+ L + EG F L+ V G+ + W N QP T
Sbjct: 8245 RL----IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITF 8300
Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
+ L ++ A D G YTC N G C++ + + E P KP
Sbjct: 8301 KNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE--------------PKKP- 8345
Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
P+F Q L+ + V +G V ++ V G+ P + WL G EI+ S+ F L
Sbjct: 8346 -PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLE 8404
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH-----------DGTQPWFISKPRSV 730
+++V D+G Y C+A N AG T++ +T+++ DG + +F+S+P+S+
Sbjct: 8405 LRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDG-RLFFVSEPQSI 8463
Query: 731 TASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790
+ + GDP P V W + G + Q D L ++ +G
Sbjct: 8464 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSG 8523
Query: 791 QYEILLKNRVGECSCQVSLMLQNSSARALPRG--REPASCEDLCGGGVGADGGGSDRYGS 848
Y + N GE V+L + + G R + G G + D
Sbjct: 8524 LYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEE-EEIDIMEL 8582
Query: 849 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTK 908
L+ P + + D RG+L+ +Q EE + E+E+++ R +K +
Sbjct: 8583 LKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIE-RSERDEKEFEE 8641
Query: 909 TLSEDDLKEIPAEQMDFRANLQRQVKPK---TVSEEERKVHSPQQVDFRSVLAKKGTSKT 965
+S + E + +++ Q K V E + K++ P+ + KGT K
Sbjct: 8642 LVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPE----IKLSWYKGTEKL 8697
Query: 966 PVPEKVPPPKPATPDFRSVLGGKKKLPAEN----GSSSAETLNAKAVESSKPLSNAQPSG 1021
+P+ S+ G + L +N + + + S+K L+ +P+
Sbjct: 8698 ---------EPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAK-LTVIEPAW 8747
Query: 1022 P--LKPVGNAKPAETLK-----PMGNAKP-----AETLKPMGNAKP--DENLKSASKEEL 1067
L+ V K +T + N K LKP G K + + + ++
Sbjct: 8748 ERHLQDV-TLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADV 8806
Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
+ + + CK T E R E++ F +++Q++ V+E + +C+VS D A
Sbjct: 8807 RAEDQGQYTCKYEDL-ETSAELRIEAEPI--QFTKRIQNIVVSEHQSATFECEVSFD-DA 8862
Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAK-NDAGQAECSCQVT 1186
+ W L ++ +G ++I P+D G+Y +A+ G+A + ++
Sbjct: 8863 IVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELY 8922
Query: 1187 VDDAPASENTKAPEM-KSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMP-PQIIQFP 1244
+ K P++ SR P ++P ++ P + PP A P P ++ P
Sbjct: 8923 LTTKEIKLELKPPDIPDSRVPIPTMP----------IRAVPPEEIPPVVAPPIPLLLPTP 8972
Query: 1245 EDQK 1248
E++K
Sbjct: 8973 EEKK 8976
Score = 189 bits (480), Expect = 2e-47
Identities = 207/837 (24%), Positives = 323/837 (38%), Gaps = 133/837 (15%)
Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85
S+ + E P F P + +GA E ++G P V+W+++ + + SG ++ + +
Sbjct: 7392 SLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI---M 7448
Query: 86 RGTFSLVIHAVHEE--DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
F IH ++ + D G+Y C+ATN G+ T GS A +
Sbjct: 7449 SENFLTSIHILNVDAADIGEYQCKATNDVGSD------TCVGSIALK------------- 7489
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL-Q 202
PP+F KL + G+ + I G V W K + +
Sbjct: 7490 ---------------APPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVR 7534
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA---------------- 246
S + +S + L+ V + G YTC + N +G A
Sbjct: 7535 ESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPES 7594
Query: 247 -----------ELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSK 295
E ++ G + + ++ K SD + +++ +K S L + A
Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKIS-FFNKVSGLKIINVAPSD- 7652
Query: 296 NCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE 355
S ++ Q ++S S + S RT P + +K + L + V E
Sbjct: 7653 ---------SGVYSFEVQNPVGKDSCTASLQVSDRTVPPS-FTRKLKETNGLSGSSVVME 7702
Query: 356 PRAPGLGVLSPS----GEE----RKRPAPPRPATFPTRQPGL---GSQDVVSKAANRRIP 404
+ G +S S G E RK T L S D A N
Sbjct: 7703 CKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATN---- 7758
Query: 405 MEGQRDSAFP-------KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457
M G + + P F KP +V V F V G P V+WF + +
Sbjct: 7759 MAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPG 7818
Query: 458 EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517
+ ED+ + L L T SG Y+C SN G+ SC+ L ++ A F
Sbjct: 7819 DRCNVSLEDSVAE-LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA------KFV 7871
Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDAL 574
L D ++ +G+ +L+ + GTP +TW NG P Q T A L I +
Sbjct: 7872 KRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSST 7931
Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
ED G Y C ENA G+ SCSA + + E P F++ L +KV
Sbjct: 7932 VEDAGQYNCYIENASGKDSCSAQILILEP-------------------PYFVKQLEPVKV 7972
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
G ++ Q++G P V W +++ + + R +L +V D+G Y
Sbjct: 7973 SVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYI 8032
Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHW 754
C+A NS GEV LTVQE P F + R V ++G V+ CAI+G +V W
Sbjct: 8033 CKAENSVGEVSASTFLTVQE--QKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSW 8090
Query: 755 LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
+DGK L KD+ + + ++ TL + K AGQY N +G S L+L
Sbjct: 8091 YKDGKPL-KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 8146
Score = 188 bits (478), Expect = 4e-47
Identities = 216/961 (22%), Positives = 369/961 (38%), Gaps = 152/961 (15%)
Query: 414 PKFESKPQ-SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472
P+F K + S+ VK+++ ++ C++ G P+ +V W+ + T ++ + D+ + L
Sbjct: 7305 PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVA-VL 7363
Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
+ DSG Y+C A NA G S S +L+V+ + P LK G D
Sbjct: 7364 EMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLK------GADVH 7417
Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENAL 589
L+C ++GTP ++W + + ++ + E + +HI + D G Y C A N +
Sbjct: 7418 LECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDV 7477
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G +C + + AP P F++ LSD+ + G +V + + G
Sbjct: 7478 GSDTCVGSIALK--------------AP-----PRFVKKLSDISTVVGKEVQLQTTIEGA 7518
Query: 650 PPPEVIWLHNGNEI-QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 708
P V+W + EI +ES++ +L V P + G YTC+ N AG A
Sbjct: 7519 EPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFA 7578
Query: 709 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF 768
L+V EP + KP S+ + G + + C +AG P + W +DGK L D +
Sbjct: 7579 TLSVLEPAT-----IVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDN-KY 7632
Query: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRG--REPA 826
++ V L + V P +G Y ++N VG+ SC SL + S R +P R+
Sbjct: 7633 KISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV---SDRTVPPSFTRKLK 7689
Query: 827 SCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEA 886
L G V + YGS P W E G ++ K + +T A
Sbjct: 7690 ETNGLSGSSVVME---CKVYGS-----PPISVSWFHE--GNEISSGRKYQTTLTDNT-CA 7738
Query: 887 IRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVH 946
+ +E+ D D ++T D+ P TV E V
Sbjct: 7739 LTVNMLEESDSGDY--TCIATNMAGSDECS-----------------APLTVREPPSFVQ 7779
Query: 947 SPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVL--GGKKKLPAENGSSSAETLN 1004
P +D VL + T + + PP + S L G + + E+ + E +
Sbjct: 7780 KPDPMD---VLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFD 7836
Query: 1005 AKAVES-------SKPLSNAQPSGPLKPVGNAKPAETL--------KPM-------GNAK 1042
+S S A + L AK + L KP+ G
Sbjct: 7837 VDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPP 7896
Query: 1043 PAETLKPMG-NAKPDE--NLKSASKEELKKDVKNDV------NCKRGHAGTTDNEKRSES 1093
+ T K G N P + N+ + K + + + V NC +A D+
Sbjct: 7897 ISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQIL 7956
Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153
P F ++L+ V V+ G LQCQ++ P + W L+ T + ++
Sbjct: 7957 ILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVA 8016
Query: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
++ + D G Y C A+N G+ S +TV +
Sbjct: 8017 TLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE------------------------ 8052
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
+PP + D + G V ++G++PI+ +W K
Sbjct: 8053 --------------------QKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYK 8092
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
K +++S +++ +N + L I + G Y+ N +GS + L + + +P
Sbjct: 8093 DGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNP 8152
Query: 1334 P 1334
P
Sbjct: 8153 P 8153
Score = 183 bits (465), Expect = 1e-45
Identities = 200/829 (24%), Positives = 321/829 (38%), Gaps = 119/829 (14%)
Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
VD P+F +N GA+ E +V G V W I SG ++
Sbjct: 5791 VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKY---- 5846
Query: 84 GIRGTFS-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ TFS L ++++ D G YTC A N +G+ + LTV+
Sbjct: 5847 --QTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE------------- 5891
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
PP F + + V G+ F+ I G P +V W +G
Sbjct: 5892 ---------------------PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA 5930
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS--- 255
L R ++ ++ + LE+ ++ G YTC+V N +G+AS + L ++ +
Sbjct: 5931 RELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLK 5990
Query: 256 --------ANRSFVRETKATNS-----DVRKEVTNVISKES-KLDSLEAAAKSKNCSSPQ 301
+S + E+ T + +K+ N+ + E + + E + +S +
Sbjct: 5991 RLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTK 6050
Query: 302 RGGSPPWAANSQPQPPRE--SKLESCKDSPRTAPQ-TPVLQKTSSSITLQAARVQPEPRA 358
R ++ + + R+ L S + P + P+ S++LQ
Sbjct: 6051 RDAG-QYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQC----QVAGT 6105
Query: 359 PGLGVLSPSGEERKRPAPPRPATFPTRQPGL--------GSQDVVSKA------ANRRIP 404
P + V G+ + RP P F L S + KA A+ +
Sbjct: 6106 PEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTV 6165
Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
Q P F + + E V C ++G +V W+ +G +R E +
Sbjct: 6166 FRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSF 6225
Query: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524
D L +L+ SG YSC+ASN G S S L + +P F
Sbjct: 6226 VD-NVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTARE---PKKSPFFDIKPVSID 6281
Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTY 581
VI G+ +C V G RITW + + I+ + TC L I D G Y
Sbjct: 6282 VIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQY 6341
Query: 582 TCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-MDGSQV 640
TC A N +G+ CSA ++V E P F++ L KV G +
Sbjct: 6342 TCQATNDVGKDMCSAQLSVKE-------------------PPKFVKKLEASKVAKQGESI 6382
Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
+ ++SG+P +V W N +E+ ES ++ + L I E ED+G Y CEA N
Sbjct: 6383 QLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNG 6442
Query: 701 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA 760
G+ LTV+ P P F KP V A G V++ C I+G P V W++D K
Sbjct: 6443 VGDASCSTALTVKAP-----PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQ 6497
Query: 761 LCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--CSCQV 807
+ +++ F++ +L + ++ G+Y N VG CSC V
Sbjct: 6498 V-RNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSV 6545
Score = 183 bits (464), Expect = 2e-45
Identities = 195/836 (23%), Positives = 324/836 (38%), Gaps = 132/836 (15%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+ + E P+F+ P L + G F +RG P +V W R + + G R C I
Sbjct: 5887 LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDR----CNIY 5942
Query: 87 ---GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
L + + G+YTC +N +G T L F K+
Sbjct: 5943 FEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRL-----FVKE------------- 5984
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
P F +L V+ G+ TG VTW K +
Sbjct: 5985 ----------------PAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITT 6028
Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA--------------------- 242
S + ++ +LEI + D G Y+C + N +G+
Sbjct: 6029 SEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPL 6088
Query: 243 ------SMSAELSIQGLDSANRSFVR-ETKATNS-DVRKEVTN-----VISKESKLDSLE 289
S+S + + G S+ + +TK + + R TN V +K + DS E
Sbjct: 6089 EAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGE 6148
Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQ-KTSSSITLQ 348
K++N S + + PP S KD +T L + + S +Q
Sbjct: 6149 YTCKAEN-SIGTASSKTVFRIQERQLPP--SFARQLKDIEQTVGLPVTLTCRLNGSAPIQ 6205
Query: 349 AARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIP---- 404
+ GVL E + AT Q L S +A+ +
Sbjct: 6206 VCWYRD-------GVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASS 6258
Query: 405 ---MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI 461
+ + P F+ KP S +V ++ F C V+G + W + +R G+
Sbjct: 6259 SARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIR-PGGNY 6317
Query: 462 EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLK 521
+ + +L +LK DSG Y+C A+N G+ CS L V+ P F L+
Sbjct: 6318 TITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE------PPKFVKKLE 6371
Query: 522 DCAVI-EGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAELHIQDALPE 576
V +G+ L+C + G+P +++W N + +Y S + VA L I +A E
Sbjct: 6372 ASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINS-VALLTINEASAE 6430
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
D G Y C A N +G SCS +TV AP P+F Q S + +
Sbjct: 6431 DSGDYICEAHNGVGDASCSTALTVK--------------AP-----PVFTQKPSPVGALK 6471
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
GS V + ++SG PP EV+W+ + +++ S+ F + SL I + D G Y C+
Sbjct: 6472 GSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCK 6531
Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
A N G + +EP P F+ K + +G +V + + G +V WL+
Sbjct: 6532 ATNEVGSDTCSCSVKFKEP-----PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLK 6586
Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG--ECSCQVSLM 810
D + +++ + + +++ TL L + ++G+Y +KN G ECS ++++
Sbjct: 6587 DRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVL 6642
Score = 176 bits (446), Expect = 2e-43
Identities = 181/789 (22%), Positives = 290/789 (36%), Gaps = 142/789 (17%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
M + AP L + G AKF ++ P + W + G+ I + C IR
Sbjct: 3450 MEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIR 3505
Query: 87 GT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
+ SL I D G+YTC+A+N G+ T LTV ++
Sbjct: 3506 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAY---------------- 3549
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
PP F ++ + G+ +F C +TG P + W K L P
Sbjct: 3550 ----------------PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSP 3593
Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263
S +S+ +LE+ + D GVY+C N G AEL I +D + F++E
Sbjct: 3594 SPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII--IDKPH--FIKE 3649
Query: 264 TKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLE 323
+ S + K+V E ++D R + W+ + Q PP + +
Sbjct: 3650 LEPVQSAINKKV----HLECQVDE-------------DRKVTVTWSKDGQKLPPGKD-YK 3691
Query: 324 SCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFP 383
C + + P+ + S G V + S E AT
Sbjct: 3692 ICFEDKIATLEIPLAKLKDS----------------GTYVCTASNEAGSSSC---SATVT 3732
Query: 384 TRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESK-PQSQEVKENQTVKFRCEVSGIPK 442
R+P P F K S + ++ + C++ G P
Sbjct: 3733 VREP--------------------------PSFVKKVDPSYLMLPGESARLHCKLKGSPV 3766
Query: 443 PEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL 502
+V WF + + ++ +Y L + + DSG+YSC A N G SCS +
Sbjct: 3767 IQVTWFKNNKEL-SESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 3825
Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RS 559
V++ PSF L+ ++ G + +LQC V GT I+W + + I+ + R
Sbjct: 3826 ------VIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRL 3879
Query: 560 TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSK 619
+ + L I D G Y C+ N +G+ C A + E
Sbjct: 3880 FSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKE----------------- 3922
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
P F++ + DL + G VT+ V G+ P V W+ I+E
Sbjct: 3923 --PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAV 3980
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
L I +V G YTC A N AG + L V+EP I + + + G
Sbjct: 3981 LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAK-----IIERAELIQVTAGDPAT 4035
Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
+ +AG P W +DG+ L + + + +V L + +GQY + N
Sbjct: 4036 LEYTVAGTPELKPKWYKDGRPLVA-SKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNE 4094
Query: 800 VGECSCQVS 808
VG SC+ +
Sbjct: 4095 VGSSSCETT 4103
Score = 172 bits (437), Expect = 2e-42
Identities = 123/402 (30%), Positives = 180/402 (44%), Gaps = 34/402 (8%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P F KPQSQ+V N V+ + V G + WF + + + V++D S L
Sbjct: 4768 PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELH-SGAARSVWKDDTSTSLE 4826
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
L A+ DSGTY C SN G + TL V+ PS VL++ GQ
Sbjct: 4827 LFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRN-----GQSTTF 4881
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
+C + GTP R++W L+G I + + G+A I A E+ GTY C A N G
Sbjct: 4882 ECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAG 4941
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
SCS + V E P F++ L ++V+ S V + +V+G P
Sbjct: 4942 TASCSIELKVKEP-------------------PTFIRELKPVEVVKYSDVELECEVTGTP 4982
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
P EV WL N EI+ S+ + R + +L I + P DTG Y C N G +
Sbjct: 4983 PFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRV 5042
Query: 711 TVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV 770
++EP P FI K + T L S +AG P ++ WL+D + L +D + +
Sbjct: 5043 ALKEP-----PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVY-I 5096
Query: 771 LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
+ V TL ++ V H+G+Y KN G C L++Q
Sbjct: 5097 SFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138
Score = 165 bits (417), Expect = 4e-40
Identities = 182/788 (23%), Positives = 302/788 (38%), Gaps = 136/788 (17%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E P+FI N ++A F+ V G P +TW ++ Q + + +
Sbjct: 5044 LKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISF-VDSV 5102
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
+L I +V G+YTC+A N SG + L V+
Sbjct: 5103 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE----------------------- 5139
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
P + K V V E C + G P+ +V WLK + PS S
Sbjct: 5140 -----------PAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFS 5188
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
+S +N + I V + D G YT V N G +S A L + + SF + K T
Sbjct: 5189 MSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLD-QNIPPSFTK--KLTK 5245
Query: 269 SDVRKEVTNVISKESKLD-SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
D K + + I E K+ SL +A+ W + + C +
Sbjct: 5246 MD--KVLGSSIHMECKVSGSLPISAQ--------------WFKDGKEISTSAKYRLVCHE 5289
Query: 328 SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQP 387
+ + + +++ T + + V + G+ + PP P RQ
Sbjct: 5290 RSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK---------EPPSFLVKPGRQQ 5340
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
+ V KA + P F+ K F+ +V + P+
Sbjct: 5341 AIPDSTVEFKAILK----------GTPPFKIK------------WFKDDVELVSGPKCFI 5378
Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
LEG+ + +L L +G Y+C +N G SC+ L V
Sbjct: 5379 GLEGS----------------TSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE- 5421
Query: 508 AVMEVAPSFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEA 563
P F L+ +++ G L+C + G+P R+ W N + + R T
Sbjct: 5422 -----PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFID 5476
Query: 564 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 623
VA + + + ED G + C A+N G SCS V V E PV S P P
Sbjct: 5477 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP----------PVFSSFP--P 5524
Query: 624 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 683
I ++ + ++V++ ++SG PP EV+W + +++ S+ + + S+ I
Sbjct: 5525 I-------VETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHIL 5577
Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 743
V D G Y C+A N G + ++EP P F+SK S+T G+ + +
Sbjct: 5578 NVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEP-----PRFVSKLNSLTVVAGEPAELQAS 5632
Query: 744 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 803
I G V WL++ + + +++ + + E+V TL K +P +AG+Y +KN G
Sbjct: 5633 IEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMR 5692
Query: 804 SCQVSLML 811
+LM+
Sbjct: 5693 ENMATLMV 5700
Score = 164 bits (416), Expect = 6e-40
Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%)
Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
+VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++
Sbjct: 32748 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 32807
Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
+ S K+ Q T+ + A E S P T L
Sbjct: 32808 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 32862
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y
Sbjct: 32863 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 32922
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285
TC V N +G S S +L+I+ + V K + + V++E++ + ++
Sbjct: 32923 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 32982
Query: 286 DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
EA ++ SK S + S + +K + RT +
Sbjct: 32983 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 33042
Query: 337 VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388
T SI + R+ + G GV + EE + T +Q
Sbjct: 33043 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 33100
Query: 389 LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
+ + +SK + + + S P F S+P+SQ + E Q V F CE+SG
Sbjct: 33101 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 33160
Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
P PE+ WF P+ ++ + + L + A DSG Y+ A N +GQ CS
Sbjct: 33161 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 33217
Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560
T + L ++E PS VL+ D LQ S + Q +Q + S
Sbjct: 33218 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 33259
Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613
EA + A + ++ ++ ++S S+++ + S +
Sbjct: 33260 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 33319
Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671
A + P SD+ + +G +T+ +G P PEV W G +I QE FH
Sbjct: 33320 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 33379
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
E +L I +V +D G YT N G
Sbjct: 33380 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 33410
Score = 163 bits (413), Expect = 1e-39
Identities = 181/791 (22%), Positives = 289/791 (36%), Gaps = 144/791 (18%)
Query: 31 EAPAFILPPRN-LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
E P FI P L ++ G + FE ++ G P+ +V+W+ +G IT+ + + I G
Sbjct: 4859 EPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISF-IDGLA 4917
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
+ I E+ G Y CEA N +G ++EL V+
Sbjct: 4918 TFQISGARVENSGTYVCEARNDAGTASCSIELKVKE------------------------ 4953
Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
PP F +L V V + C++TG P +VTWLK N ++ S + ++
Sbjct: 4954 ----------PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTL 5003
Query: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269
+++ + L I + D G Y C+V N G S S ++++ SF+++ + T
Sbjct: 5004 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK----EPPSFIKKIENT-- 5057
Query: 270 DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP----WAANSQPQPPRESKLESC 325
T V+ + S A GSPP W + Q ++ S
Sbjct: 5058 ------TTVLKSSATFQSTVA-------------GSPPISITWLKDDQILDEDDNVYISF 5098
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
DS T V S T QA + SG ER A +
Sbjct: 5099 VDSVATLQIRSVDNGHSGRYTCQAK--------------NESGVERCY------AFLLVQ 5138
Query: 386 QPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEV 445
+P +V KA +S +V E + C V+G P+ +V
Sbjct: 5139 EPA----QIVEKA----------------------KSVDVTEKDPMTLECVVAGTPELKV 5172
Query: 446 AWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
W +G + +E+ + + + +DSG Y+ N G SC L
Sbjct: 5173 KWLKDGKQIVPSRYFSMSFENNVASFR-IQSVMKQDSGQYTFKVENDFGSSSCDAYL--- 5228
Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCE 562
R+ + PSF+ L + G ++C V G+ W +G+ I + R C
Sbjct: 5229 RVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCH 5288
Query: 563 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622
L + + ED YTC N G +CS +TV E
Sbjct: 5289 ERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE-------------------P 5329
Query: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682
P FL + + S V + G PP ++ W + E+ G+ L +
Sbjct: 5330 PSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNL 5389
Query: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK-PRSVTASLGQSVLIS 741
V TG YTC N G +L V EP P F+ K S G S +
Sbjct: 5390 YSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEP-----PKFVKKLEASKIVKAGDSSRLE 5444
Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
C IAG P V W R+ L + + + + V + + + +G + +N G
Sbjct: 5445 CKIAGSPEIRVVWFRNEHEL-PASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAG 5503
Query: 802 ECSCQVSLMLQ 812
SC ++++
Sbjct: 5504 STSCSTKVIVK 5514
Score = 159 bits (402), Expect = 2e-38
Identities = 114/408 (27%), Positives = 182/408 (44%), Gaps = 16/408 (3%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P+ + Q V+ + +F +SG P+P+++W+ E + + D + L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3297
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526
L++A D+ Y+C A N G + S +L VE V+ P+ + L+D
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3357
Query: 527 EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583
EGQ QC V GT + +++W + P ++ R T +L I +A PED GTYT
Sbjct: 3358 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3416
Query: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
+A NA+GQVS +A +++ +S + AP+ + + L+V G T
Sbjct: 3417 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFT 3476
Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
++ P W G EI ES+ SL I D G YTC+A N G
Sbjct: 3477 CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 3536
Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
V A LTV E + P F+S+P+S+T +G++ C + G P W +DG AL
Sbjct: 3537 VSCTATLTVTEAY---PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAAL-S 3592
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
+ ++ + E+ L L + G Y N+ G CQ L++
Sbjct: 3593 PSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII 3640
Score = 156 bits (395), Expect = 2e-37
Identities = 172/788 (21%), Positives = 296/788 (37%), Gaps = 148/788 (18%)
Query: 29 LTEAPAFILP-PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
+TE P F+ + +K G +++ E ++ G PE +V W RN + + ++ + I
Sbjct: 5419 VTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTF-IDS 5477
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
+ ++ + ED G + CEA N +G+ + ++ V+
Sbjct: 5478 VAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK----------------------- 5514
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
P ++ PP T +K ++ C+++G P +V W K L+ S +
Sbjct: 5515 ----EPPVFSSFPPIVET------LKNAEVS-LECELSGTPPFEVVWYKDKRQLRSSKKY 5563
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
++ KN + I V+ D+G Y C N G + + +
Sbjct: 5564 KIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL----------------- 5606
Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP---PWAANSQPQPPRESKLES 324
KE +SK + L + A + + G P W + K E
Sbjct: 5607 -----KEPPRFVSKLNSLTVV--AGEPAELQASIEGAQPIFVQWL---------KEKEEV 5650
Query: 325 CKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPT 384
++S + + TLQ A+ +P + + G R+ AT
Sbjct: 5651 IRESENIR-----ITFVENVATLQFAKAEPANAGKYICQIKNDGGMRE-----NMATLMV 5700
Query: 385 RQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPE 444
+P + +V KA PM V +T C+V+G P+
Sbjct: 5701 LEPAV----IVEKAG----PM------------------TVTVGETCTLECKVAGTPELS 5734
Query: 445 VAWFLEGTPV-RRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ 503
V W+ +G + Q+ Y S L +L +D+GTY+ N G+ SC+ +
Sbjct: 5735 VEWYKDGKLLTSSQKHKFSFYNKISS--LRILSVERQDAGTYTFQVQNNVGKSSCTAVVD 5792
Query: 504 VERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITW------LLNGQPIQYA 557
V A V PSF+ LK+ + G +L+C V G+ + W +++G Q
Sbjct: 5793 VSDRA---VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQ-- 5847
Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
+T V L + D G YTC+A N G C A +TV E
Sbjct: 5848 -TTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE--------------- 5891
Query: 618 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 677
P F++ L+V+ G VT T + G PP +V W E+ + + + T
Sbjct: 5892 ----PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTV 5947
Query: 678 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737
L + + +G YTC N+AG+ L V+EP F+ + + G+S
Sbjct: 5948 AELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEP-----AAFLKRLSDHSVEPGKS 6002
Query: 738 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797
+++ G +V W +DG + + ++ E L + AGQY ++
Sbjct: 6003 IILESTYTGTLPISVTWKKDGFNI-TTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIE 6061
Query: 798 NRVGECSC 805
N G C
Sbjct: 6062 NEAGRDVC 6069
Score = 152 bits (384), Expect = 3e-36
Identities = 153/659 (23%), Positives = 252/659 (38%), Gaps = 74/659 (11%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP+ +L V V+ G+ RF I+GRPQP+++W K L + L
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3297
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
+ +D VYTC N G A+ SA LS++ V E + + ++ +I
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVSPDQEMPVYPPAII 3348
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQP-QPPRESKLESCKDSPRTAPQTPVL 338
+ + E C W + + +P R ++ +D+ +
Sbjct: 3349 TPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQ-------- 3400
Query: 339 QKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKA 398
L+ A PE V S + + A P + ++ +
Sbjct: 3401 --------LEIAEAYPEDEGTYTFVASNAVGQVSSTA-----NLSLEAP----ESILHER 3443
Query: 399 ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE 458
+ I ME + A P + K + EV KF CE+ P WF G + +
Sbjct: 3444 IEQEIEMEMK---AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESD 3500
Query: 459 GSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSS 518
+ L +L+ + D G Y+C ASN G +SC+ TL V P+F S
Sbjct: 3501 -KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTE----AYPPTFLS 3555
Query: 519 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI---QDALP 575
K G+ C+V GTPV W +G + + + + HI +
Sbjct: 3556 RPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTI 3615
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
+D G Y+C A N G C A + + +K P F++ L ++
Sbjct: 3616 QDRGVYSCKASNKFGADICQAELIIIDK-------------------PHFIKELEPVQSA 3656
Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 695
+V + QV + V W +G ++ +D+ +L I +D+GTY C
Sbjct: 3657 INKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVC 3716
Query: 696 EAWNSAGEVRTQAVLTVQEPHDGTQPWFISK-PRSVTASLGQSVLISCAIAGDPFPTVHW 754
A N AG A +TV+EP P F+ K S G+S + C + G P V W
Sbjct: 3717 TASNEAGSSSCSATVTVREP-----PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTW 3771
Query: 755 LRDGKALCK-DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
++ K L + +T + +E + + KV+ +G Y N VG SC ++++
Sbjct: 3772 FKNNKELSESNTVRMYFVNSEAILDITDVKVE--DSGSYSCEAVNDVGSDSCSTEIVIK 3828
Score = 150 bits (378), Expect = 1e-35
Identities = 184/788 (23%), Positives = 286/788 (36%), Gaps = 141/788 (17%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91
AP F P RN+ T + + ++ G +V+W ++G+ I + R+ + + GT SL
Sbjct: 4112 APFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRI-AFVEGTASL 4170
Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVET 151
I V D G +TC ATN G++ + L V+
Sbjct: 4171 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE-------------------------- 4204
Query: 152 RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE 211
PP F TK G V G G + W KGN L +++
Sbjct: 4205 --------PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITK 4256
Query: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV 271
+ LE++ V D G YTC V N +G SA L ++ +FV + + +
Sbjct: 4257 EALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK----EPATFVEKLEPSQLLK 4312
Query: 272 RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP----WAANSQPQPPRESKLESCKD 327
+ + T + K + G+PP W AN RE K ES K
Sbjct: 4313 KGDATQLACKVT--------------------GTPPIKITWFAND-----REIK-ESSKH 4346
Query: 328 SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQP 387
T VL+ T I SGE Q
Sbjct: 4347 RMSFVESTAVLRLTDVGI-------------------EDSGE-----------YMCEAQN 4376
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
GS S + P F K E KP EV + V EV+G P E+ W
Sbjct: 4377 EAGSDHCSSIVIVKESPY-------FTK-EFKP--IEVLKEYDVMLLAEVAGTPPFEITW 4426
Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
F + T + R + + L +LK D+G Y C +N G CS R+
Sbjct: 4427 FKDNT-ILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICS-----ARV 4480
Query: 508 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAG 564
+ E PSF ++ + + G Q +++G+ +TWL + I R T E
Sbjct: 4481 TLRE-PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENN 4539
Query: 565 VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
VA L++ + G Y C A+N G CSA ++V K A I
Sbjct: 4540 VASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV------------------KEPATI 4581
Query: 625 FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684
+ +S + V G T+ V+ SG W +G E+ + T L I
Sbjct: 4582 TEEAVS-IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIIS 4640
Query: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744
+D+G YT E N G +A + V + P F K + + + G + + C +
Sbjct: 4641 TEKKDSGEYTFEVQNDVGRSSCKARINVLDLI--IPPSFTKKLKKMDSIKGSFIDLECIV 4698
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
AG ++ W +D + + + + F L + +++ +G Y N+ G
Sbjct: 4699 AGSHPISIQWFKDDQEISASEKYKFSFHDNTAF-LEISQLEGTDSGTYTCSATNKAGHNQ 4757
Query: 805 CQVSLMLQ 812
C L ++
Sbjct: 4758 CSGHLTVK 4765
Score = 149 bits (375), Expect = 3e-35
Identities = 114/402 (28%), Positives = 173/402 (43%), Gaps = 34/402 (8%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P FE P S EV ++ F + G P +V WF + E ED + L
Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTE-LE 6892
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
L + + +SG YSC +N G SC+ L V+ A +F L D +V G VL
Sbjct: 6893 LFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPA------TFVKRLADFSVETGSPIVL 6946
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALPEDHGTYTCLAENAL 589
+ + GTP ++W+ + I + C + E L I ++ ED+ Y+CL EN
Sbjct: 6947 EATYTGTPPISVSWIKDEYLISQSER-CSITMTEKSTILEILESTIEDYAQYSCLIENEA 7005
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
GQ C A V+V E P F++ L ++ + G T+ +V G
Sbjct: 7006 GQDICEALVSVLEP-------------------PYFIEPLEHVEAVIGEPATLQCKVDGT 7046
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
P + W +++ + + + + SL I +V D G Y+C+A NS G V + AV
Sbjct: 7047 PEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAV 7106
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
L ++ P+F K + V +LG V C I G V W +DG L KD + +
Sbjct: 7107 LVIKARK--LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDG-VLLKDDANLQ 7163
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
+V TL + + H GQY N +G S L+L
Sbjct: 7164 TSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLIL 7205
Score = 143 bits (360), Expect = 2e-33
Identities = 101/400 (25%), Positives = 178/400 (44%), Gaps = 35/400 (8%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P F+ KP S ++ ++ F+C V+G ++ W + +R G+ ++ + L
Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIR-PGGNYKMTLVENTATLT 7270
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV- 532
+LK D+G Y+C ASN G+ SCS L V+ P F L+ +++ +F
Sbjct: 7271 VLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE------PPRFIKKLEPSRIVKQDEFTR 7324
Query: 533 LQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
+C + G+P ++ W + IQ + R + VA L + + ED G YTC A NA
Sbjct: 7325 YECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAA 7384
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G S S + V E PIF + ++ + G+ V + ++ G
Sbjct: 7385 GSASSSTSLKVKEP-------------------PIFRKKPHPIETLKGADVHLECELQGT 7425
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
PP V W + E++ + + S+ I V D G Y C+A N G
Sbjct: 7426 PPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGS 7485
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
+ ++ P P F+ K ++ +G+ V + I G +V W +D + +++ +
Sbjct: 7486 IALKAP-----PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIW 7540
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
+ +E++ TL +V+P +AG+Y +KN G C +L
Sbjct: 7541 ISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATL 7580
Score = 141 bits (356), Expect = 5e-33
Identities = 118/449 (26%), Positives = 181/449 (40%), Gaps = 52/449 (11%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P F S+P+S + KF C V+G P E W +G + + + + H L
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSP-NWRISDAENKHILE 3609
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
L +D G YSC ASN G C Q E + + + P F L+ + L
Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADIC----QAELIIIDK--PHFIKELEPVQSAINKKVHL 3663
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
+C V +TW +GQ + + E +A L I A +D GTY C A N G
Sbjct: 3664 ECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAG 3723
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
SCSA VTV E S ++ V PS P G + ++ G+P
Sbjct: 3724 SSSCSATVTVREPPS-----FVKKVDPSYLMLP-------------GESARLHCKLKGSP 3765
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
+V W N E+ ES ++ L I +V ED+G+Y+CEA N G +
Sbjct: 3766 VIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 3825
Query: 711 TVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV 770
++EP P FI G + L+ C ++G + W +D K + + + + +
Sbjct: 3826 VIKEP-----PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQI-RSSKKYRL 3879
Query: 771 LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML------------------Q 812
+ + L + G+YE ++ N VG+C C + +L Q
Sbjct: 3880 FSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQ 3939
Query: 813 NSSARALPRGREPASCEDLCGGGVGADGG 841
+ +A RG EP S + G V + G
Sbjct: 3940 TVTLQAAVRGSEPISVTWMKGQEVIREDG 3968
Score = 140 bits (353), Expect = 1e-32
Identities = 165/790 (20%), Positives = 277/790 (35%), Gaps = 139/790 (17%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+ + E P FI + + + + + + E V G P +VTW +N + I S ++ L +
Sbjct: 4949 LKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRV- 5007
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
F+L I D G+Y C +N G+ + + ++
Sbjct: 5008 SVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE--------------------- 5046
Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
PP F K+ F + G P +TWLK + L
Sbjct: 5047 -------------PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDN 5093
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKA 266
V +S + + L+I V+ G YTC N SG A L +Q
Sbjct: 5094 VYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ--------------- 5138
Query: 267 TNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCK 326
E ++ K +D E + C G+P E K++ K
Sbjct: 5139 -------EPAQIVEKAKSVDVTEKDPMTLECVV---AGTP------------ELKVKWLK 5176
Query: 327 DSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 386
D + P +++ + R+Q + SG+ TF
Sbjct: 5177 DGKQIVPSRYFSMSFENNVA--SFRIQSVMK-------QDSGQ----------YTFKVEN 5217
Query: 387 P-GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEV 445
G S D + ++ IP P F K + ++ C+VSG
Sbjct: 5218 DFGSSSCDAYLRVLDQNIP---------PSFTKKLTKMDKVLGSSIHMECKVSGSLPISA 5268
Query: 446 AWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
WF +G + V + S L + D+ Y+C SN G +CS L V+
Sbjct: 5269 QWFKDGKEISTSAKYRLVCHER-SVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327
Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CE 562
V P + D V + ++GTP +I W + + E
Sbjct: 5328 EPPSFLVKPGRQQAIPDSTV------EFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLE 5381
Query: 563 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622
+ L++ G YTC N +G SC+ + V E
Sbjct: 5382 GSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE-------------------P 5422
Query: 623 PIFLQGLSDLKVMD-GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
P F++ L K++ G + +++G+P V+W N +E+ S+ + + +
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQ 5482
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
+ + ED+G + CEA N AG + V+EP P F S P V V +
Sbjct: 5483 MNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP-----PVFSSFPPIVETLKNAEVSLE 5537
Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
C ++G P V W +D + L + + +++ ++ + V G+Y +N VG
Sbjct: 5538 CELSGTPPFEVVWYKDKRQL-RSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG 5596
Query: 802 E--CSCQVSL 809
C C V L
Sbjct: 5597 SDTCVCTVKL 5606
Score = 137 bits (345), Expect = 1e-31
Identities = 113/395 (28%), Positives = 167/395 (42%), Gaps = 50/395 (12%)
Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS---GTYSCTASN 491
C+V+G VAWF E T + S Y+ S +C L+ + DS G Y+C A+N
Sbjct: 5821 CKVAGSSPISVAWFHEKTKIV----SGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAAN 5876
Query: 492 AQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551
G C L V+ PSF + V+ G++ +RGTP ++ W
Sbjct: 5877 VAGSDECRAVLTVQE------PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA 5930
Query: 552 QPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 608
+ + E VAEL + + G YTC+ N GQ SC+ + V E
Sbjct: 5931 RELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE------ 5984
Query: 609 SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668
P A FL+ LSD V G + + +G P V W +G I SE
Sbjct: 5985 -----------PAA--FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEK 6031
Query: 669 FHFEQRGTQHSLCIQEVF---PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
+ T CI E+ D G Y+CE N AG A+++ EP P+F++
Sbjct: 6032 CNIV---TTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEP-----PYFVT 6083
Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
+ + A++G SV + C +AG P TV W + G + T + +V TLV KV
Sbjct: 6084 ELEPLEAAVGDSVSLQCQVAGTPEITVSWYK-GDTKLRPTPEYRTYFTNNVATLVFNKVN 6142
Query: 786 PWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
+G+Y +N +G S + +Q R LP
Sbjct: 6143 INDSGEYTCKAENSIGTASSKTVFRIQE---RQLP 6174
Score = 136 bits (343), Expect = 2e-31
Identities = 107/403 (26%), Positives = 170/403 (42%), Gaps = 30/403 (7%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P F ++ + E +V +C+V+G P+ V+W+ +G R Y L
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWY-KGDTKLRPTPEYRTYFTNNVATLV 6137
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
K DSG Y+C A N+ G S +++ ++ PSF+ LKD G L
Sbjct: 6138 FNKVNINDSGEYTCKAENSIGTASSKTVFRIQE---RQLPPSFARQLKDIEQTVGLPVTL 6194
Query: 534 QCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG 590
C + G+ ++ W +G + + +++ VA L I G Y+C A N LG
Sbjct: 6195 TCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLG 6254
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
S SA +T E K S P KP + + V+ G V+G
Sbjct: 6255 TASSSARLTAREPKKS-------PFFDIKPVS---------IDVIAGESADFECHVTGAQ 6298
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
P + W + EI+ ++ G L I +V D+G YTC+A N G+ A L
Sbjct: 6299 PMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 6358
Query: 711 TVQEPHDGTQPWFISK-PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
+V+EP P F+ K S A G+S+ + C I+G P V W R+ L ++ +
Sbjct: 6359 SVKEP-----PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSEL-HESWKYN 6412
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
+ V L + + +G Y N VG+ SC +L ++
Sbjct: 6413 MSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455
Score = 136 bits (342), Expect = 2e-31
Identities = 119/403 (29%), Positives = 165/403 (40%), Gaps = 33/403 (8%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P+F K V+ R V G V W + V R+ + + L
Sbjct: 6551 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQ 6610
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
L +SG Y C N G CS L V A + P + V G F L
Sbjct: 6611 LGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKP------EPMTVTTGNPFAL 6664
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
+C V GTP W +G+ + T VA L I A D G Y+ +N++G
Sbjct: 6665 ECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVG 6724
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
+ +C+ V+VH S+ ++P P F++ L D+ + G+ V + +VSG+
Sbjct: 6725 KSNCT--VSVHV------SDRIVP--------PSFIRKLKDVNAILGASVVLECRVSGSA 6768
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
P V W +GNEI +L + + P DTG YTC A N AG AVL
Sbjct: 6769 PISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVL 6828
Query: 711 TVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV 770
TVQEP P F P SV G S+ + I G P V W + + L G
Sbjct: 6829 TVQEP-----PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELV--PGESCN 6881
Query: 771 LQNEDVFT-LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
+ ED T L L +VQP +G Y L+ N G SC L ++
Sbjct: 6882 ISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924
Score = 134 bits (336), Expect = 1e-30
Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%)
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
S + P + S+ P + Q V + KF + +G P+P W +G +
Sbjct: 32834 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 32893
Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
Q G ++ ED G +L + K T DSG Y+CT N+ G +S S L ++
Sbjct: 32894 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 32942
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+KD E Q Q + TP + ++ + Q A + E ++E Q+ L
Sbjct: 32943 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 32994
Query: 576 -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631
++ + ++E + S + VHE+ K+S+ SE + A K + +
Sbjct: 32995 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 33047
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + +G ++ + ++G +V W+ NG E+ SE++ + G+ +L I++ D G
Sbjct: 33048 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 33105
Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
TC + G V+ Q LT+ + P FIS+PRS + GQ+VL +C I+G+P P
Sbjct: 33106 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 33164
Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
+ W ++ + + + + ++ +V++L ++ +G+Y I KN G+CS SLM+
Sbjct: 33165 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223
Query: 812 QNSSARALPRGREPA 826
LP EP+
Sbjct: 33224 -------LPLVEEPS 33231
Score = 130 bits (327), Expect = 1e-29
Identities = 102/386 (26%), Positives = 168/386 (43%), Gaps = 33/386 (8%)
Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
V F C ++G +V+W+ +G + + + +++ L +L+ G Y+C+AS
Sbjct: 7133 VAFECRINGSEPLQVSWYKDGV-LLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSAS 7191
Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 550
N G S S L L+ EV P F + G+ +C V GT +ITW +
Sbjct: 7192 NPLGTASSSAKLI---LSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKD 7248
Query: 551 GQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607
+ I+ + T A L + D G YTC A N G+ SCSA + V E
Sbjct: 7249 NREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEP---- 7304
Query: 608 KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM-TVQVSGNPPPEVIWLHNGNEIQES 666
P F++ L +++ + T ++ G+P +V+W + EIQES
Sbjct: 7305 ---------------PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQES 7349
Query: 667 EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK 726
F + L + + ED+G YTCEA N+AG + L V+EP P F K
Sbjct: 7350 SKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEP-----PIFRKK 7404
Query: 727 PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQP 786
P + G V + C + G P V W +D + L + ++++ + ++ + V
Sbjct: 7405 PHPIETLKGADVHLECELQGTPPFHVSWYKDKREL-RSGKKYKIMSENFLTSIHILNVDA 7463
Query: 787 WHAGQYEILLKNRVGECSCQVSLMLQ 812
G+Y+ N VG +C S+ L+
Sbjct: 7464 ADIGEYQCKATNDVGSDTCVGSIALK 7489
Score = 129 bits (325), Expect = 2e-29
Identities = 105/407 (25%), Positives = 168/407 (41%), Gaps = 33/407 (8%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P+F SK S V + + + + G V W E V R+ +I + L
Sbjct: 5610 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQ 5669
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQV-ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
KA ++G Y C N G TL V E ++E A + V G+
Sbjct: 5670 FAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMT-------VTVGETCT 5722
Query: 533 LQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
L+C V GTP + W +G+ + Q + + ++ L I +D GTYT +N +
Sbjct: 5723 LECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNV 5782
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G+ SC+A V V ++ P F + L + + G+ + +V+G+
Sbjct: 5783 GKSSCTAVVDVSDRA----------------VPPSFTRRLKNTGGVLGASCILECKVAGS 5826
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
P V W H +I + +L + + D G YTC A N AG +AV
Sbjct: 5827 SPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAV 5886
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
LTVQEP P F+ +P + G++V + I G P V+W R + L K
Sbjct: 5887 LTVQEP-----PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG-DRCN 5940
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
+ + V L L + +G+Y ++ N G+ SC L ++ +A
Sbjct: 5941 IYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAA 5987
Score = 125 bits (314), Expect = 4e-28
Identities = 107/395 (27%), Positives = 171/395 (43%), Gaps = 37/395 (9%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEG-SIEVYEDAGSHYLCLLKARTRDSG 483
V+ + +G P V+W + + + E SI + E S L +L++ D
Sbjct: 6938 VETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEK--STILEILESTIEDYA 6995
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
YSC N GQ C E L + P F L+ + G+ LQC V GTP
Sbjct: 6996 QYSCLIENEAGQDIC------EALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEI 7049
Query: 544 RITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
RI+W ++ A + + VA L I D G Y+C A+N++G V+ SA + +
Sbjct: 7050 RISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVI 7109
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
+K LP P F + L D+ G V +++G+ P +V W +G
Sbjct: 7110 KARK--------LP--------PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDG 7153
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPED---TGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
+++ + Q H++ ++ D G Y C A N G + A L + E H+
Sbjct: 7154 VLLKDDANL---QTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSE-HE 7209
Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
P+F KP SV +LG+S C + G + W +D + + + G++++ E+
Sbjct: 7210 -VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREI-RPGGNYKMTLVENTA 7267
Query: 778 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
TL + KV AGQY N G+ SC L +Q
Sbjct: 7268 TLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 7302
Score = 122 bits (306), Expect = 3e-27
Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++
Sbjct: 30151 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 30207
Query: 795 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848
+L+N+ G+ + + + + S P G P +D+ V AD GG+D G
Sbjct: 30208 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 30263
Query: 849 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906
+ W + VRG +++ E R Q L + V+
Sbjct: 30264 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 30321
Query: 907 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963
KT L+ + P E +D + + + +V + ++ + K +
Sbjct: 30322 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 30380
Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022
KT + + PD + ++ A+N +ET A + V P G
Sbjct: 30381 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 30436
Query: 1023 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070
L+ + +K + TL KP K D K ++KE +K
Sbjct: 30437 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 30496
Query: 1071 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
+N+ R T + K + G AP +++++DV G+ L CQ
Sbjct: 30497 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 30555
Query: 1121 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180
+ P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E
Sbjct: 30556 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 30615
Query: 1181 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
S ++ + P P P K
Sbjct: 30616 TSSKLLLQATPQFH---------------------------------PGYPLK------- 30635
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299
E G ++ L G TW +K +Q SE++ +EN+E+ + L +
Sbjct: 30636 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 30691
Query: 1300 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG
Sbjct: 30692 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 30751
Query: 1360 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P +
Sbjct: 30752 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 30811
Query: 1418 ESELTTVGEKPEEP 1431
S + + E+P
Sbjct: 30812 VSSVVIIKSPFEKP 30825
Score = 121 bits (303), Expect = 7e-27
Identities = 105/406 (25%), Positives = 179/406 (44%), Gaps = 37/406 (9%)
Query: 409 RDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAG 468
RD A P F ++ + N T + C+++G V+WF +G + + + + G
Sbjct: 4109 RDIA-PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE-G 4166
Query: 469 SHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEG 528
+ L +++ D+G ++C A+N+ G S L +++ PSF + V+ G
Sbjct: 4167 TASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL------IVQEPPSFVTKPGSKDVLPG 4220
Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLA 585
L+ + +G+ I W + + S T EA + L + D GTYTC
Sbjct: 4221 SAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKV 4280
Query: 586 ENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQ 645
N G V CSA + V E + ++ + PS+ LK D +Q + +
Sbjct: 4281 SNVAGGVECSANLFVKEPAT-----FVEKLEPSQL-----------LKKGDATQ--LACK 4322
Query: 646 VSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVR 705
V+G PP ++ W N EI+ES + L + +V ED+G Y CEA N AG
Sbjct: 4323 VTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDH 4382
Query: 706 TQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
+++ V+E P+F + + + V++ +AG P + W +D L
Sbjct: 4383 CSSIVIVKE-----SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGR 4437
Query: 766 GHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--CSCQVSL 809
+ +Q+ V +LK V AG+Y+ + N VG CS +V+L
Sbjct: 4438 KYKTFIQDHLVSLQILKFVAA-DAGEYQCRVTNEVGSSICSARVTL 4482
Score = 118 bits (295), Expect = 6e-26
Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)
Query: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680
T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L
Sbjct: 941 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 1000
Query: 681 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714
I+E F ED+G +TC A N AG V T L VQ
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 715 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
P + P+FI+KP G SV+ C + G+P P V+W + G
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 760 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ +
Sbjct: 1121 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1177
Query: 817 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875
L + ++ + V + G PG+ + + E+E + + K
Sbjct: 1178 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1232
Query: 876 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932
V R + E+ QE F + L K++ KT E+ L+E E+M +
Sbjct: 1233 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1288
Query: 933 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981
V+ S + ++ + + ++ V S P+P +++ + DF
Sbjct: 1289 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1344
Query: 982 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035
R+ L LP + G +A N K NA SG P P+G TL
Sbjct: 1345 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1396
Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095
+P+ + +L P ++ + A + + + S+ +
Sbjct: 1397 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1453
Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152
P F K EG+ +V P W +G+ + T +++ ++G+
Sbjct: 1454 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1513
Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212
S+ I A P D G + VA+N AG++ S +TV+
Sbjct: 1514 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1550
Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
+ + P ++ ++ ++ G +E+ + TG W+
Sbjct: 1551 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1590
Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327
K I ++ +++E ++ + L I + + YT NK G + + +VN+ V
Sbjct: 1591 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1650
Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348
+P+P P GT A +I + L
Sbjct: 1651 FAEPEPERKLIIPRGTYRAKEIAAPEL 1677
Score = 117 bits (294), Expect = 8e-26
Identities = 105/405 (25%), Positives = 166/405 (40%), Gaps = 38/405 (9%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYED-AGSHYL 472
P F K +S T F+ + G V W + + + +E+ S YL
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYL 4545
Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLA-VMEVAPSFSSVLKDCAVIEGQDF 531
++ + G Y C A N G CS L V+ A + E A S V +G
Sbjct: 4546 SGIEVK--HDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSID-------VTQGDPA 4596
Query: 532 VLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587
LQ GT W +GQ + +Y S + V+ L I +D G YT +N
Sbjct: 4597 TLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDT-VSILKIISTEKKDSGEYTFEVQN 4655
Query: 588 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
+G+ SC A + V + ++P P F + L + + GS + + V+
Sbjct: 4656 DVGRSSCKARINV--------LDLIIP--------PSFTKKLKKMDSIKGSFIDLECIVA 4699
Query: 648 GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 707
G+ P + W + EI SE + F L I ++ D+GTYTC A N AG +
Sbjct: 4700 GSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCS 4759
Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
LTV+EP P+F+ KP+S + V + + G T+ W +D K L
Sbjct: 4760 GHLTVKEP-----PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAAR 4814
Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
V +++ +L L + +G Y L N VG + + +L ++
Sbjct: 4815 -SVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK 4858
Score = 115 bits (289), Expect = 3e-25
Identities = 104/403 (25%), Positives = 159/403 (39%), Gaps = 34/403 (8%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P F K QTV + V G V W ++G V R++G I++ G L
Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTW-MKGQEVIREDGKIKMSFSNGVAVLI 3982
Query: 474 LLKARTRDSGTYSCTASNAQG-QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
+ + G Y+C A N G Q S + E ++E A V G
Sbjct: 3983 IPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQ-------VTAGDPAT 4035
Query: 533 LQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
L+ +V GTP + W +G+P+ + R + + VA+L A D G YT N +
Sbjct: 4036 LEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEV 4095
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G SC TV ++ AP F + L ++ + + +++G+
Sbjct: 4096 GSSSCETTFTVLDRD----------------IAPFFTKPLRNVDSVVNGTCRLDCKIAGS 4139
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
P V W +G EI S+ + SL I V D G +TC A NS G +
Sbjct: 4140 LPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGA 4199
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
L VQEP P F++KP S G +V + G T+ W + K L G
Sbjct: 4200 LIVQEP-----PSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSG-GSCY 4253
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
+ + +L L V+ +G Y + N G C +L ++
Sbjct: 4254 ITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK 4296
Score = 115 bits (288), Expect = 4e-25
Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483
+ E Q + + ++G +V W L G + E Y +GS +K A RD G
Sbjct: 33050 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 33105
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
+C + +G + C + L + + + AP+F S + + EGQ+ + C + G P P
Sbjct: 33106 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 33163
Query: 544 RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
I W N PI + + V L I++A D G YT A+N GQ S +A + V
Sbjct: 33164 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
LP+ +P+ + L+ D + GS + +VQ+S + +
Sbjct: 33224 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 33269
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
+ + F Q +QE F E + + N ++ + ++ G
Sbjct: 33270 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 33328
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779
P + P ++ G+ + ++CA G+P P V W G+ + ++ G F + +D+ TL
Sbjct: 33329 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 33388
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813
++ VQ G Y + L N G S V++ +++
Sbjct: 33389 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 33422
Score = 115 bits (287), Expect = 5e-25
Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
F +++ + EG F CK++G P P++ W K R+ E+ M L+
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1343
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282
G+AS+ + + + +F K N I
Sbjct: 1344 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1376
Query: 283 SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342
KL +E AA G+P + +P S++ S SPR+ ++P+
Sbjct: 1377 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1415
Query: 343 SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402
R+ P +P R PA PA PG ++ R
Sbjct: 1416 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1454
Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
P F KP S + E QT +F +V G P PE WF +G +
Sbjct: 1455 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1505
Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
V ++ G+ L ++ A DSG ++ A N G+ S S L VE + +V P F LK+
Sbjct: 1506 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1564
Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577
+ EG ++ G P P I WL N P +Y + E G A L I + +D
Sbjct: 1565 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1624
Query: 578 HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617
YT A N G+ C V V + + + ++P AP
Sbjct: 1625 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1684
Query: 618 -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662
K P F + L+ L++ +++ G+P V WLH+G
Sbjct: 1685 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1744
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714
++ + SL + D+G TC A N G T A L V++
Sbjct: 1745 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1804
Query: 715 ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744
H+G +P + P V G++ C +
Sbjct: 1805 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1864
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G
Sbjct: 1865 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1922
Query: 805 CQVSLMLQNSS--ARALPRGREP 825
+V L +Q L R EP
Sbjct: 1923 HKVKLEIQQREDFRSVLRRAPEP 1945
Score = 113 bits (282), Expect = 2e-24
Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
+K S RK E L + AP + +V G + V P EV W HNG
Sbjct: 32353 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 32412
Query: 662 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682
E+QES D H + GT ++C
Sbjct: 32413 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 32472
Query: 683 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718
+ VFPE T T EA +S EV++Q T + H
Sbjct: 32473 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 32532
Query: 719 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752
+ ++KPRS+T G+S SC G+P PTV
Sbjct: 32533 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 32592
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q
Sbjct: 32593 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 32651
Query: 813 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848
+ + ++ R + P +++
Sbjct: 32652 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 32711
Query: 849 LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
L P + +L+ E +++ VL+ + T + +++ Q +
Sbjct: 32712 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 32771
Query: 901 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954
++ L+E D + EI E + NLQ + K++ E+ K+ ++ D +
Sbjct: 32772 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 32831
Query: 955 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983
S + +K K P P P P+P T D ++
Sbjct: 32832 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 32891
Query: 984 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015
+ GGK KL + G SS+ L KA++ ++
Sbjct: 32892 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 32951
Query: 1016 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067
+ Q + + P A E + A +E +K M AK E L + ASK EE+
Sbjct: 32952 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 33008
Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
KK + H T + SE T K + + EG++L+L+ ++
Sbjct: 33009 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 33066
Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ W LNG L ++ GS +++I++A D G+ C++K G +C +T+
Sbjct: 33067 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 33126
Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247
+ E+ SDA P I P Q
Sbjct: 33127 ----------SKEL----------------SDA-----------------PAFISQPRSQ 33143
Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
+ G++V +++G W K I S ++ + S N L I A G
Sbjct: 33144 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 33203
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S
Sbjct: 33204 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 33263
Query: 1368 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423
+ S++ + + + S + Q + E + + + G S +Q S++
Sbjct: 33264 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 33321
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEV 1447
G + PK E SD E +V
Sbjct: 33322 AGIRGIPPKIEALPSDISIDEGKV 33345
Score = 112 bits (279), Expect = 4e-24
Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
+N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E
Sbjct: 1298 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1357
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
D G YT A+N G + +L VE A LG P TL R +P +R I
Sbjct: 1358 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1415
Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
P F K EGQ R
Sbjct: 1416 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1475
Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
F K+ GRP P+ W G + V +++G Q L I D G +T + N
Sbjct: 1476 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1535
Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
+G++S+S L+++ ++ FV + K N I + S+L+ A + N
Sbjct: 1536 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1584
Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
W NS P + ++E K + V Q
Sbjct: 1585 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1638
Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
T + ++ +PEP ++ P G R K A P P Q D+
Sbjct: 1639 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1695
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453
K ++ P F+ K S +K F C ++ G P V W +G P
Sbjct: 1696 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1744
Query: 454 VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502
+ + + + G L A +RDSG +C A+N G S TL
Sbjct: 1745 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1803
Query: 503 -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536
++E L M + + V D V+EG+ +C
Sbjct: 1804 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1863
Query: 537 VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594
V G P P++ W LNGQ I+ ++ G+ L I D D G AEN G +
Sbjct: 1864 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1923
Query: 595 SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
+ + +++ R +L AP +P + G +V + T + E
Sbjct: 1924 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1975
Query: 654 VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694
V+ L I +ESE+ F++R + S E + E
Sbjct: 1976 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 2035
Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738
E + E+ + + E T P F + +S T G
Sbjct: 2036 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2095
Query: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
+ G P P W ++G + + + ++V LV++ V + + N
Sbjct: 2096 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2155
Query: 799 RVGECSCQVSLMLQ 812
GE S L++Q
Sbjct: 2156 IAGETSSHAFLLVQ 2169
Score = 111 bits (278), Expect = 6e-24
Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
+PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L
Sbjct: 18898 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 18956
Query: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355
I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+
Sbjct: 18957 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 19016
Query: 1356 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE
Sbjct: 19017 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 19076
Query: 1415 PSQESELTTVGE--KPEEPKD 1433
P ++ P EPK+
Sbjct: 19077 PLTSPKMVAQFPFGVPSEPKN 19097
Score = 110 bits (275), Expect = 1e-23
Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567
AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I + G Y+ A N GQ + +A + V K+E AP P F+Q
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168
Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713
ED+GTY+ A NS G + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 109 bits (272), Expect = 3e-23
Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)
Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58
Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
S L I AV + + G+Y+ +ATNGSG T EL V+ A
Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PP F +L + V++G R ++TG P P V + + +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
+S++ + L I +D G Y+ N G+A+ +AEL +QG
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ +A S R+T+ + + ++ + E +D AA + +P R PP +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263
Query: 312 SQPQPP 317
P PP
Sbjct: 264 RSPTPP 269
Score = 109 bits (272), Expect = 3e-23
Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y
Sbjct: 13702 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 13761
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y +
Sbjct: 13762 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 13820
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426
E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T +
Sbjct: 13821 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 13880
Query: 1427 KPEEPKDEVEVSD 1439
P P +E SD
Sbjct: 13881 DPPGPPTRLEPSD 13893
Score = 105 bits (262), Expect = 4e-22
Identities = 101/411 (24%), Positives = 157/411 (38%), Gaps = 48/411 (11%)
Query: 415 KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
+F + +V E + F CEVS P V W + ++ + I++ ++ H L +
Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3116
Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
R D+G Y+ A + +L V S+ K+ VIE Q V++
Sbjct: 3117 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3167
Query: 535 CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
V V W +G I + + E + + I + D G YT +A
Sbjct: 3168 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3224
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
+R S L AP P LQ L + V G +SG
Sbjct: 3225 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3265
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
P P++ W + F G +++L + E FPED YTCEA N G T A
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3325
Query: 710 LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
L+V+ P D P + I+ + S GQ C ++G + +D K
Sbjct: 3326 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3383
Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
K + F + Q ED + L + + P G Y + N VG+ S +L L+
Sbjct: 3384 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3434
Score = 102 bits (253), Expect = 5e-21
Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
+++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A
Sbjct: 26876 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 26935
Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
+ + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG
Sbjct: 26936 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 26995
Query: 1361 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
+ + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP
Sbjct: 26996 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 27052
Query: 1417 QESEL 1421
+ +
Sbjct: 27053 ESDSV 27057
Score = 101 bits (252), Expect = 6e-21
Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)
Query: 1236 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
+PP + ++ E V+AG +V + G T W +I+ EH VE
Sbjct: 17506 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 17565
Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352
S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW
Sbjct: 17566 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 17625
Query: 1353 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411
DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G
Sbjct: 17626 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 17685
Query: 1412 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469
P +S T K P P + V+D E V + + ++ +Y +E R
Sbjct: 17686 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 17743
Query: 1470 LGSGKFGQV 1478
+GK+ +V
Sbjct: 17744 EVTGKWVRV 17752
Score = 101 bits (252), Expect = 6e-21
Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++
Sbjct: 22540 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 22596
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL
Sbjct: 22597 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 22656
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N
Sbjct: 22657 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 22716
Query: 1410 YGTSEPSQESELTTVGE--KPEEPK 1432
YG EP + + P+ PK
Sbjct: 22717 YGVGEPLESEPVVAKNPFVVPDAPK 22741
Score = 101 bits (251), Expect = 8e-21
Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)
Query: 1243 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302
F + VRAG S+ LF G T W K + S + +++ S LT+ +
Sbjct: 28363 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 28420
Query: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362
G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+
Sbjct: 28421 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 28479
Query: 1363 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421
+ Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E
Sbjct: 28480 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 28539
Query: 1422 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471
E+P P+ D V+ S +P+ D + QK SDF+ +E
Sbjct: 28540 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 28598
Query: 1472 SGKFGQVFRLVEK 1484
V RLVEK
Sbjct: 28599 KQLTFTVERLVEK 28611
Score = 100 bits (250), Expect = 1e-20
Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L +
Sbjct: 21465 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 21524
Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
+ G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG
Sbjct: 21525 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 21584
Query: 1361 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
+ + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP +
Sbjct: 21585 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 21644
Query: 1420 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471
+ V P+ PK+ EV D P+ D + IN Y +E R
Sbjct: 21645 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 21694
Query: 1472 SGKFGQVFRLVEKKT 1486
K GQ + KKT
Sbjct: 21695 -DKAGQRWIKCNKKT 21708
Score = 100 bits (249), Expect = 1e-20
Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y
Sbjct: 22159 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 22218
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y +
Sbjct: 22219 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 22278
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
E D++ TW+ + AT T+ L EY+FR+ A N YG S
Sbjct: 22279 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 22324
Score = 100 bits (248), Expect = 2e-20
Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)
Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567
V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A
Sbjct: 1289 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1348
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623
L I LPED G YT A N G CS + V Y L PV+ + +P
Sbjct: 1349 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1408
Query: 624 -------------------------------------------------IFLQGLSDLKV 634
+F+ K
Sbjct: 1409 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1468
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G
Sbjct: 1469 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1527
Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
+T A N AG +LTV+ +P F+ K ++V G + + G+P P +
Sbjct: 1528 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1587
Query: 753 HWLRD 757
WL++
Sbjct: 1588 VWLKN 1592
Score = 100 bits (248), Expect = 2e-20
Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A++ S +L +V +PL FI P ++ + E AKFE V P+
Sbjct: 11818 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 11868
Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
W + Q IT RF L+ G + + + A +E + + E + SG
Sbjct: 11869 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 11927
Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
+ VT + F +L + KT F
Sbjct: 11928 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 11987
Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
+++ I E P F KL E C+I+ P
Sbjct: 11988 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 12047
Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248
V W K ++PS + ++L + + D+G YTC G+ K S ++
Sbjct: 12048 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 12104
Query: 249 ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287
S++ +++ F ET+ + D+ + I +E K+ S
Sbjct: 12105 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 12162
Query: 288 LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341
L NC Q GG AAN + K L KD TA +T
Sbjct: 12163 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 12218
Query: 342 SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395
S L+ +++P + + P E + R + G +
Sbjct: 12219 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 12268
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
+K + + +F + Q V+E T CEVS +V WF GT +
Sbjct: 12269 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 12325
Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
+ + E+ D L + D TY+C A + + SC+ L V+
Sbjct: 12326 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 12375
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572
F L D V E + +C + ++ W +G I+ + + V L I
Sbjct: 12376 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 12434
Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632
L +D Y+C A S +TV E+++ +F + L+++
Sbjct: 12435 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 12472
Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
+V + + + +VS P EVIW EI E+ + G + L IQ ED G
Sbjct: 12473 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 12531
Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
Y C +S RT + V E FISKP+++ G+ C+I+ + FP V
Sbjct: 12532 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 12582
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796
W RD K L + ++V+ + LV+K G Y +++
Sbjct: 12583 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 12625
Score = 100 bits (248), Expect = 2e-20
Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288
MPP I E +V G +V + K+ G T TW K ++ + H+
Sbjct: 16116 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 16174
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348
++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + +
Sbjct: 16175 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 16234
Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407
TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A
Sbjct: 16235 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 16294
Query: 1408 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
N YG EP + +PE ++ V + D V ++T+N E+ D
Sbjct: 16295 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 16343
Score = 99.8 bits (247), Expect = 2e-20
Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%)
Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343
E + +K PQR S P +P P E+ +++ ++KT+
Sbjct: 739 ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 796
Query: 344 SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403
T + V PR SP K P G + ++ +A +
Sbjct: 797 LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 842
Query: 404 PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463
E S+ K ++ VK ++T R P P+ F + + E +EV
Sbjct: 843 QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 898
Query: 464 YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523
++ G + + R+ A+ + VE + P+ S LK+
Sbjct: 899 KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 952
Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580
VIEG+ L+C + G P P +TW I+ + + T ++G+A L I++A ED G
Sbjct: 953 TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 1012
Query: 581 YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614
+TC A N G VS S ++ V EK+++ +E
Sbjct: 1013 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1072
Query: 615 -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671
P +P AP F+ K+++G V QV GNP P V W +G + + +
Sbjct: 1073 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1132
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
++ + L I F +D G YT N GE A L + ++
Sbjct: 1133 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1178
Score = 99.4 bits (246), Expect = 3e-20
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++
Sbjct: 23623 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 23679
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351
+ L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+
Sbjct: 23680 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 23739
Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410
W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y
Sbjct: 23740 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 23799
Query: 1411 GTSEPSQES 1419
G EP + +
Sbjct: 23800 GVGEPLESA 23808
Score = 97.8 bits (242), Expect = 9e-20
Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%)
Query: 426 KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+E VK+ C++ + +V W+ + E YED G L + D GT
Sbjct: 31580 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 31638
Query: 485 YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522
Y C N G+ S C T++ + + ++E P F+ L +
Sbjct: 31639 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 31698
Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576
G++ ++ P P +TW +GQ I+ + + G+ +L I +
Sbjct: 31699 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 31758
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
D YT +A N G+ SC A +TV L P P+F + L++ + +
Sbjct: 31759 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 31808
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695
G V ++VSG PPP + W +G + + G ++L I++ PEDTG Y
Sbjct: 31809 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 31868
Query: 696 EAWNSAGEVRTQAVLTVQ 713
A N+AG QA L V+
Sbjct: 31869 TATNTAGSTSCQAHLQVE 31886
Score = 97.4 bits (241), Expect = 1e-19
Identities = 69/251 (27%), Positives = 116/251 (46%), Gaps = 39/251 (15%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G AS+ + S S +R+ + ++P F + P ++ + G +A FE V G
Sbjct: 6243 GQYSCSASNPLGTASSS---ARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQP 6299
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
++TW ++ + I GG + + C + T L I V + D G+YTC+ATN G + +L
Sbjct: 6300 MRITWSKDNKEIRPGGNYTITC-VGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 6358
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-GRVVVKEGQMGRF 180
+V+ PPKF KL V K+G+ +
Sbjct: 6359 SVKE----------------------------------PPKFVKKLEASKVAKQGESIQL 6384
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
CKI+G P+ +V+W + + L S + ++S N + +L I+ + +D G Y C NG G
Sbjct: 6385 ECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVG 6444
Query: 241 KASMSAELSIQ 251
AS S L+++
Sbjct: 6445 DASCSTALTVK 6455
Score = 97.4 bits (241), Expect = 1e-19
Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y
Sbjct: 27575 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 27634
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T++++N + + + + P P G +I++ S+ LSW +GG + YSI
Sbjct: 27635 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 27694
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 27695 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 27742
Score = 97.4 bits (241), Expect = 1e-19
Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI
Sbjct: 32374 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 32433
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278
+ DD G Y + N G+AS A L + G D + R + V E+T
Sbjct: 32434 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 32493
Query: 279 --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
+S K +EA++ + S + + S + ++++S ++ +
Sbjct: 32494 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 32550
Query: 337 VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396
+K +++ AAR+ +PR+ + GE + PT L V+S
Sbjct: 32551 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 32602
Query: 397 KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450
+A ++ + + + S S E V EN K E + I K V
Sbjct: 32603 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 32660
Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509
+P R + V +K+ R S S + + + + T +V+ L V
Sbjct: 32661 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 32714
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563
P + LK A + L C V + + +TW +G+ ++ +
Sbjct: 32715 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 32771
Query: 564 GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609
G EL I + D G Y C G Q A+ ++HEK KS +K+
Sbjct: 32772 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 32831
Query: 610 EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
++P AP + + GL D V S V+ +G P P IW +G
Sbjct: 32832 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 32891
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
I + + + L I + D+G YTC NSAG V + LT++ D
Sbjct: 32892 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 32946
Score = 96.7 bits (239), Expect = 2e-19
Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y +
Sbjct: 19367 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 19425
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
+ +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P
Sbjct: 19426 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 19473
Score = 96.7 bits (239), Expect = 2e-19
Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%)
Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
K + I+KTS + + R + E AF + I EG + + G + V
Sbjct: 33018 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 33068
Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
W NG +T+ + G+ G+ +L I D G TC + G + +LT+
Sbjct: 33069 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 33126
Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
SK L D APA ++P + EGQ F+C+
Sbjct: 33127 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 33156
Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S
Sbjct: 33157 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 33216
Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
+A L + L V + V+ + S SL+ +++S S+ +
Sbjct: 33217 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 33259
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
+ S ++S E K S ++ Q ++ +SSS +
Sbjct: 33260 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 33304
Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
G+ + + E S + KA R IP PK E+ P
Sbjct: 33305 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 33336
Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480
+ E + + C +G P PEV W G + QE G + L ++ + +
Sbjct: 33337 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 33396
Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERL 507
D G Y+ + N G S + + + +
Sbjct: 33397 DGGLYTLSLGNEFGSDSATVNIHIRSI 33423
Score = 96.3 bits (238), Expect = 2e-19
Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)
Query: 1228 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
P T PP + + F + +R GE+ L G+ +G +W K + E + +
Sbjct: 16808 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 16867
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346
+ + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++
Sbjct: 16868 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 16927
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405
+ +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+
Sbjct: 16928 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 16987
Query: 1406 AINVYGTSEPSQESELTT-----VGEKPEEP 1431
A N+YG S+P + V + P++P
Sbjct: 16988 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 17018
Score = 95.9 bits (237), Expect = 3e-19
Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
+G + + + K P P I D V GE + + T +W K
Sbjct: 14366 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 14422
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P
Sbjct: 14423 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 14482
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392
ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+
Sbjct: 14483 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 14541
Query: 1393 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449
DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + +
Sbjct: 14542 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 14600
Query: 1450 RTVTINTEQKVSDFYDIEERLGSGK 1474
+ + K+ + I E++ G+
Sbjct: 14601 KPPLYDGGSKIMGY--IIEKIAKGE 14623
Score = 95.9 bits (237), Expect = 3e-19
Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%)
Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561
++A +E+ P ++ EG C + ++TW + ++ + T
Sbjct: 31561 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 31619
Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608
E GVA L+++D D GTY C N G+ S A + V KK R+
Sbjct: 31620 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 31679
Query: 609 SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
++ + L P + T P++ + G V V ++ +P P V W +G +I+ +
Sbjct: 31680 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 31734
Query: 668 D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720
+ + FE + L I V +D YT A N GE +A LTV P D T +
Sbjct: 31735 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 31794
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
P F + GQSV ++G P PT+ W +DG+ L + + D + L
Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 31854
Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
++ P G Y + N G SCQ L ++
Sbjct: 31855 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 31886
Score = 95.5 bits (236), Expect = 4e-19
Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)
Query: 1249 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G
Sbjct: 20390 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 20449
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY
Sbjct: 20450 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 20508
Query: 1368 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
+E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q +
Sbjct: 20509 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 20565
Query: 1424 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
V P P ++ EVS+ V T T++ ++ V D
Sbjct: 20566 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 20598
Score = 94.7 bits (234), Expect = 7e-19
Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VRAG S+ +F + G TW K I +EN+E+ + L I + G +
Sbjct: 20788 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 20845
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y +
Sbjct: 20846 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 20904
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E
Sbjct: 20905 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 20964
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478
P P D + + D + + + + K++ + +R GS ++ +
Sbjct: 20965 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 21014
Score = 94.7 bits (234), Expect = 7e-19
Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++
Sbjct: 25786 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 25842
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L
Sbjct: 25843 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 25902
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N
Sbjct: 25903 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 25962
Query: 1410 YGTSEP 1415
YG EP
Sbjct: 25963 YGVGEP 25968
Score = 94.4 bits (233), Expect = 9e-19
Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
+RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y
Sbjct: 29458 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 29515
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y +
Sbjct: 29516 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 29574
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E
Sbjct: 29575 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 29634
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
P P ++EV D V TVT+ E+ + D
Sbjct: 29635 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 29661
Score = 94.0 bits (232), Expect = 1e-18
Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y
Sbjct: 25406 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 25465
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y +
Sbjct: 25466 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 25524
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E
Sbjct: 25525 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 25582
Query: 1428 PEEP 1431
P P
Sbjct: 25583 PFSP 25586
Score = 93.2 bits (230), Expect = 2e-18
Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 1250 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301
+AG + + + G +W K +K +++ H ++E +EN S + I +
Sbjct: 15823 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 15882
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+ H G Y++ +NK G + A + V+D P PP SDI S LSW DGG
Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 15941
Query: 1362 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + +
Sbjct: 15942 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 16001
Query: 1421 LTTVGEK--PEEPKDEVEV 1437
TT + P +P ++++
Sbjct: 16002 RTTARDPIYPPDPPIKLKI 16020
Score = 92.8 bits (229), Expect = 3e-18
Identities = 60/220 (27%), Positives = 102/220 (46%), Gaps = 36/220 (16%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F L P ++ + G + F+ V G ++TW ++ + I GG + + + T +L
Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTL-VENTATLT 7270
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
+ V + D G+YTC A+N +G + +L V+
Sbjct: 7271 VLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE--------------------------- 7303
Query: 153 PSIWGECPPKFATKLGRV-VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE 211
PP+F KL +VK+ + R+ CKI G P+ +V W K +Q S++ +S
Sbjct: 7304 -------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF 7356
Query: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
+ + VLE+H ++ +D G YTC N +G AS S L ++
Sbjct: 7357 VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396
Score = 92.4 bits (228), Expect = 4e-18
Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
+ P F +L +K A FE R+ G P V W +G+P+ + R + G
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1759
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
SL + D G TC ATN G + L V E S ++ P K L
Sbjct: 1760 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1819
Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
+ ++ G + P V V EG+ RF C++TG PQP+V W
Sbjct: 1820 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1879
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
++ S R V +G+ L+I D G N G +L IQ + RS
Sbjct: 1880 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1937
Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
+R + + E K+D ++K +R +
Sbjct: 1938 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1997
Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
SK + + T V K+ ++ + EE+K A
Sbjct: 1998 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2057
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
T PT +P +I + ++ PK + QSQ V + FR V
Sbjct: 2058 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2102
Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
G P PE W+ G + R + + + L + DS + A N G+ S
Sbjct: 2103 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2162
Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557
L V+ ++ +F+ L+D E P ++ W +G +
Sbjct: 2163 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2218
Query: 558 --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
R + V L I D Y+C V V ++ ++ ++
Sbjct: 2219 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2264
Query: 616 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672
A + F++ L D++V + + VS PE I W HN E++ + +
Sbjct: 2265 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2315
Query: 673 QRGTQHSLCIQEVFPEDTGTYT 694
R + +L +++V ED G Y+
Sbjct: 2316 SRRGRQNLTVKDVTKEDQGEYS 2337
Score = 92.4 bits (228), Expect = 4e-18
Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290
P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++
Sbjct: 24705 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 24761
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ L + + G Y L + N G++ + + V+D+P PP G + + + L
Sbjct: 24762 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 24821
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N
Sbjct: 24822 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 24881
Query: 1410 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438
YG EP + +T KP P EVS
Sbjct: 24882 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 24911
Score = 92.4 bits (228), Expect = 4e-18
Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
T + TV+ T + MP + I P AG VEL + G P +W
Sbjct: 29723 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 29776
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
+++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP
Sbjct: 29777 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 29836
Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394
G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L
Sbjct: 29837 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 29896
Query: 1395 LPDHEYKFRVRAINVYG 1411
+EY FRV A N +G
Sbjct: 29897 TEGNEYVFRVAATNRFG 29913
Score = 92.0 bits (227), Expect = 5e-18
Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+P+T P + +N+ + EG + E + GYP P VTW+R I S F +
Sbjct: 938 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 995
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
G L+I ED G++TC A N +G + L V+ S + V++ T R
Sbjct: 996 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1055
Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
F S V T S+ E P F TK + EG F C++ G P+P V W
Sbjct: 1056 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1115
Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
K VPL R VS +++ G L I DD G YT +V N G+ S SA L
Sbjct: 1116 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 92.0 bits (227), Expect = 5e-18
Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
+AGE V++ G P T TW K K + +EN+++ S LTI + G Y
Sbjct: 27284 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 27343
Query: 1310 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I
Sbjct: 27344 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 27402
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E
Sbjct: 27403 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 27462
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474
P P ++ + D + + + + ++++ + ER G G+
Sbjct: 27463 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 27506
Score = 91.7 bits (226), Expect = 6e-18
Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y
Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 23300
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y +
Sbjct: 23301 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 23360
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
+ D+ W + AT T+ V L EY+FR+ A N YG S
Sbjct: 23361 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 23406
Score = 91.3 bits (225), Expect = 8e-18
Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)
Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301
KV+AGE V + VTG W K I++ +V SE ++L+I A
Sbjct: 15409 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 15468
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS
Sbjct: 15469 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 15527
Query: 1362 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418
+ Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ +
Sbjct: 15528 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 15587
Query: 1419 SEL 1421
++
Sbjct: 15588 DKV 15590
Score = 91.3 bits (225), Expect = 8e-18
Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)
Query: 1226 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
P P PP++I +Q ++ G+++ L + G TW K +
Sbjct: 17204 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 17263
Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
+ V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+
Sbjct: 17264 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 17320
Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401
IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y
Sbjct: 17321 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 17380
Query: 1402 FRVRAINVYG 1411
FRV A N YG
Sbjct: 17381 FRVAAENQYG 17390
Score = 91.3 bits (225), Expect = 8e-18
Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)
Query: 1232 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
PKA +PP+I + +KV RA ++ LF + G W R + +
Sbjct: 21849 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 21906
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
+E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++
Sbjct: 21907 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 21965
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
+S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV
Sbjct: 21966 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 22025
Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431
A N YG P++ +E E+P P
Sbjct: 22026 LAENEYGIGLPAETAESVKASERPLPP 22052
Score = 90.5 bits (223), Expect = 1e-17
Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)
Query: 1249 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
V AG + + V+G P T TW M R QE+ +E + S + I ++ H G
Sbjct: 16536 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 16592
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y
Sbjct: 16593 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 16651
Query: 1367 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
IE +S + W + T + VQ L+ Y FR+ A N G + SE +
Sbjct: 16652 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 16711
Query: 1426 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475
E PE P+D +EV EV TVT+ D Y +E RL G+ KF
Sbjct: 16712 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 16763
Query: 1476 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524
K T + + KE + +S +N + K C
Sbjct: 16764 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 16805
Score = 90.1 bits (222), Expect = 2e-17
Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
+RAG S+ LF + G W K +I+++ + V +S + L + + G Y
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 23011
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y +
Sbjct: 23012 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 23070
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E
Sbjct: 23071 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 23130
Query: 1428 PEEP 1431
P+ P
Sbjct: 23131 PQPP 23134
Score = 90.1 bits (222), Expect = 2e-17
Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)
Query: 1228 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278
P P +++++P+ D++ + G V G + T PI C W K + I
Sbjct: 30118 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 30177
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G
Sbjct: 30178 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 30235
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397
DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L +
Sbjct: 30236 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 30295
Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454
EY FRV A N +G S+P + E T PE P + EV D + + +
Sbjct: 30296 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 30355
Query: 1455 NTEQKVSDFY 1464
+ +V+ +Y
Sbjct: 30356 DGGSRVTGYY 30365
Score = 89.4 bits (220), Expect = 3e-17
Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)
Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679
AP F Q L + V++GS T +SG P PEV W +G I S +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122
Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
+ + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 800 VGECSCQVSLMLQ 812
VG + L++Q
Sbjct: 182 VGRATSTAELLVQ 194
Score = 89.0 bits (219), Expect = 4e-17
Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%)
Query: 408 QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467
Q++ P P+ V E +T +FRC V+G P+P+V W+L G +R+ + Y+
Sbjct: 1835 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1892
Query: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527
G HYL ++ ++ D+G TA N +G + L++++ F SVL+
Sbjct: 1893 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1946
Query: 528 GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+ V LQ V+ P + L + I + + E+ EL +
Sbjct: 1947 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 2004
Query: 576 EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618
+ G Y + E L + W E+K + E + +
Sbjct: 2005 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2064
Query: 619 KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
KP AP + + V GS V+V G P PE W NG +I+ S+
Sbjct: 2065 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2124
Query: 670 H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728
+ + L I++V ED+ + +A N AGE + A L VQ T F + +
Sbjct: 2125 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2181
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758
V A ++ +PF V W +DG
Sbjct: 2182 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2211
Score = 87.8 bits (216), Expect = 9e-17
Identities = 69/286 (24%), Positives = 118/286 (41%), Gaps = 46/286 (16%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F ++L+ V V + + L+C+V+ PP + W N + ++++K L+ S+ ++ I
Sbjct: 4955 PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHI 5014
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA----SENTKAPEMKSRRPKSSL--- 1210
K P D G Y+C+ N+ G CS +V + + P+ ENT S +S++
Sbjct: 5015 TKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGS 5074
Query: 1211 PPVLGT-------------------ESDATVKKKPAPKTPP------------------- 1232
PP+ T +S AT++ +
Sbjct: 5075 PPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAF 5134
Query: 1233 -KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
P QI++ + V + + L V GT + W+K KQI S + + N
Sbjct: 5135 LLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENN 5194
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
+ I + ++ G YT VEN GS L V+D+ PP+ T
Sbjct: 5195 VASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFT 5240
Score = 87.8 bits (216), Expect = 9e-17
Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)
Query: 1232 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285
PK + P I + VRAG + LF V G TW K +++ +
Sbjct: 18597 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 18653
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+
Sbjct: 18654 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 18712
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
+S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV
Sbjct: 18713 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 18772
Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431
A+N YG P+ + + EP
Sbjct: 18773 TAVNEYGPGVPTDVPKPVLASDPLSEP 18799
Score = 87.8 bits (216), Expect = 9e-17
Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)
Query: 1228 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
P P P I+ PE + +RAG ++ L+ V G P TW K +
Sbjct: 19675 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 19734
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
++ + +++++ + L + G Y L +EN G ++ + + V+D P PP
Sbjct: 19735 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 19793
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397
+I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L
Sbjct: 19794 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 19853
Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428
Y FRV A N YG +P + + + P
Sbjct: 19854 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 19884
Score = 87.8 bits (216), Expect = 9e-17
Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)
Query: 1237 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
PP+I + +KV RA ++ LF + G W K + ++ ++E + + +
Sbjct: 25104 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 25161
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW
Sbjct: 25162 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 25220
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG
Sbjct: 25221 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280
Query: 1413 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
P++ +E V E P P V +V T TI E+ SD
Sbjct: 25281 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 25322
Score = 87.0 bits (214), Expect = 2e-16
Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VRAG S + G TW R++ + ++ +++E N ++L+I + G Y
Sbjct: 24036 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 24093
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I
Sbjct: 24094 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 24152
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
+ +S K + +++ C TSF V++L Y FRV A N +G P + + E
Sbjct: 24153 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 24212
Query: 1428 PEEP 1431
P P
Sbjct: 24213 PSPP 24216
Score = 87.0 bits (214), Expect = 2e-16
Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y
Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y +
Sbjct: 24383 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 24442
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
E D+ TW + AT T+ + L EY+FR+ A N YG S P
Sbjct: 24443 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 24490
Score = 86.7 bits (213), Expect = 2e-16
Identities = 66/269 (24%), Positives = 109/269 (40%), Gaps = 60/269 (22%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F QK V +G ++LQC++S PP ++W + K ++ +K ++ + S+ I
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHI 6517
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
D G Y C A N+ G CSC V
Sbjct: 6518 LNLEASDVGEYHCKATNEVGSDTCSCSV-------------------------------- 6545
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
K PP+ ++ D G++VEL V G QPI+ W+K R +
Sbjct: 6546 ---------------KFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGE 6590
Query: 1278 -IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV------VDK 1330
I+ESE+ ++ +N + L + + + G Y ++N G R+ LTV ++K
Sbjct: 6591 VIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEK 6650
Query: 1331 PDP---PAGTPCASD---IRSSSLTLSWY 1353
P+P G P A + + L+ W+
Sbjct: 6651 PEPMTVTTGNPFALECVVTGTPELSAKWF 6679
Score = 85.9 bits (211), Expect = 3e-16
Identities = 73/292 (25%), Positives = 125/292 (42%), Gaps = 41/292 (14%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ VA + S +L V+ E P + + + ++ G A+F + G P+
Sbjct: 3216 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3267
Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P+++W++ Q +++G + FL D ++L++ ED YTCEA N G +
Sbjct: 3268 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3324
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
L+VE P V + PP T L V EGQ R
Sbjct: 3325 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3363
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F C+++G +V+W + ++PS +++ LEI +D G YT + N
Sbjct: 3364 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3422
Query: 240 GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291
G+ S +A LS++ A S + E ++ + VI + K++ LE A
Sbjct: 3423 GQVSSTANLSLE----APESILHERIEQEIEMEMKAAPVIKR--KIEPLEVA 3468
Score = 85.5 bits (210), Expect = 4e-16
Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472
P F QS V E T F +SG P PEV+WF +G + +++ G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531
+ +SG YS A+N GQ T E L E A P+F L+ V +G
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
LQ V G P P + + +G IQ + + + E + L I +A PED GTY+ A N+
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616
+G+ + +A + V E+ ++K++ ++ A
Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211
Score = 85.5 bits (210), Expect = 4e-16
Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I D G++T A N +G ++V LTVE AVE
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1551
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
+ P F KL V +KEG + TG P P + WLK + + P ++ +
Sbjct: 1552 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1607
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
G L+I D YT +N +G+ + +++++
Sbjct: 1608 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648
Score = 84.0 bits (206), Expect = 1e-15
Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
+ G + +W K + + VE+S + L + ++ G YT+ ++N G+++
Sbjct: 20006 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
+++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W
Sbjct: 20066 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 20125
Query: 1381 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
A+ + T+F V L EY FRV A N YG E
Sbjct: 20126 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 20160
Score = 83.6 bits (205), Expect = 2e-15
Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 1237 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
PP+I FP VRAG ++++ ++G T + ++ + E +
Sbjct: 26473 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 26532
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
+ + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W
Sbjct: 26533 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 26592
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G
Sbjct: 26593 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 26652
Query: 1413 SE 1414
S+
Sbjct: 26653 SD 26654
Score = 83.2 bits (204), Expect = 2e-15
Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)
Query: 1238 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
P I++F + +++GES+ + V G TW K +I++ +M++ + +
Sbjct: 27955 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 28014
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W
Sbjct: 28015 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 28074
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G
Sbjct: 28075 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 28134
Query: 1413 SEP 1415
P
Sbjct: 28135 GRP 28137
Score = 82.8 bits (203), Expect = 3e-15
Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)
Query: 882 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938
H EE+ QQ + +++ ++S ++E + PA + + + VKP+ +
Sbjct: 722 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 772
Query: 939 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997
SE K + + S + K T V P+ A+P F K +P
Sbjct: 773 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 829
Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055
A + K LS + + + + A T+KP AE L A
Sbjct: 830 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 886
Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095
+ KS + E+KK+V + GTT E+R E
Sbjct: 887 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 940
Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + +
Sbjct: 941 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 1000
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
I +A ED G + C A N+AG SC V V + E T E + K +
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
+D ++ ++ A P A P I P QK+ G SV +V G W K
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1117
Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325
+ KV N + G KL I + G YT++V NK G A +L
Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 82.4 bits (202), Expect = 4e-15
Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%)
Query: 405 MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457
++G++ + K + +P Q+V E V+ +VS + E W +G V+
Sbjct: 2340 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2398
Query: 458 EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517
+ + + D SH L + D+G YS T L S + +V +V + P
Sbjct: 2399 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2450
Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574
LKD VIEG VL+C V V + W LN + I+ ++ + L I
Sbjct: 2451 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2508
Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
D G Y + +G+V + ++V + K ++GL DL
Sbjct: 2509 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2544
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
+ V V++S + +V+W EI+ S + E G + L + + +D G YT
Sbjct: 2545 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2603
Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753
AGE T LTV ISKP T + Q + C +A +P
Sbjct: 2604 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2651
Query: 754 WLRDGKAL 761
WLRDGK L
Sbjct: 2652 WLRDGKHL 2659
Score = 82.4 bits (202), Expect = 4e-15
Identities = 61/234 (26%), Positives = 96/234 (41%), Gaps = 46/234 (19%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F ++L+ V A KK+ L+CQV D T+ W+ +G+ L K + E + ++ I
Sbjct: 3644 PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEI 3703
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
A +D G Y C A N+AG + CS VTV + P
Sbjct: 3704 PLAKLKDSGTYVCTASNEAGSSSCSATVTVREPP-------------------------- 3737
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+ VKK + P + P GES L K+ G+ I TW K K+
Sbjct: 3738 --SFVKK-----------VDPSYLMLP-------GESARLHCKLKGSPVIQVTWFKNNKE 3777
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ ES +++ + + L I + E G Y+ N +GS + + + P
Sbjct: 3778 LSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 3831
Score = 82.4 bits (202), Expect = 4e-15
Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)
Query: 1086 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
D E R++ + AP K QD+ V GK L + + P A W + L T
Sbjct: 12987 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 13046
Query: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
+++ S + +K D+G YK V +N G+AE + V D P
Sbjct: 13047 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 13091
Query: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
PV E T + + ++ + G S ++ G V
Sbjct: 13092 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 13128
Query: 1265 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322
+ I TW+ + + E + G + + + G + +N + +R
Sbjct: 13129 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 13188
Query: 1323 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W
Sbjct: 13189 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 13241
Query: 1383 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
T R+ S V D++ EY FRVRA N G +PS + V + E P V ++
Sbjct: 13242 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 13301
Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493
D+ + V + + I ER GK + +LV + T KV K
Sbjct: 13302 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 13361
Query: 1494 FFKAYSAKEKENIRQEISIMNCL 1516
+ SA+ K + I+ L
Sbjct: 13362 YLYRVSAENKAGVSDPSEILGPL 13384
Score = 82.4 bits (202), Expect = 4e-15
Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG S + G W K ++ + V+ +++ + LTI A + G Y
Sbjct: 26198 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 26255
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I
Sbjct: 26256 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 26314
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E +++ K W + C S+ V +L Y FRV N +G P++ E + EK
Sbjct: 26315 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 26374
Query: 1428 PEEPK 1432
P P+
Sbjct: 26375 PSPPE 26379
Score = 82.4 bits (202), Expect = 4e-15
Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G
Sbjct: 30907 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 30966
Query: 662 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
EI + + ++ +G H L I V +D Y A N G V A L V+ P
Sbjct: 30967 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 31026
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L
Sbjct: 31027 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 31085
Query: 780 VLKK-VQPWHAGQYEILLKNRVG 801
V V+ AG Y + KNR G
Sbjct: 31086 VFPNGVERKDAGFYVVCAKNRFG 31108
Score = 82.0 bits (201), Expect = 5e-15
Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)
Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
R D+M L E P F LP N G +F + +PEP VTW+++GQ I G +
Sbjct: 31679 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 31738
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ + +G + L I++V +D +YT A N G +LTV L P
Sbjct: 31739 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 31791
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
TL P F L +EGQ F +++G P P + W K
Sbjct: 31792 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 31832
Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
PL + + E L I +D G Y N +G S A L ++ L
Sbjct: 31833 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 31892
Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
+ F + + V+K++ + L E+
Sbjct: 31893 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 31924
Score = 81.6 bits (200), Expect = 6e-15
Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306
V+AG+++ L V G W K + + S +K++ + SK ++ A++ G
Sbjct: 18213 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 18272
Query: 1307 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y
Sbjct: 18273 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 18331
Query: 1367 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423
+E ++ W AT + V L+ +EY FRVRA N GT P++ + T
Sbjct: 18332 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 18391
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464
+KP P D EV+ ++E V + + + ++ ++
Sbjct: 18392 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 18431
Score = 81.6 bits (200), Expect = 6e-15
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)
Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L
Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 30591
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
+ ED G YTC A N GEV T + L +Q P + K + A +G ++ +
Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 30649
Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800
G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N
Sbjct: 30650 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 30708
Query: 801 GECSCQVSLMLQN 813
G + + +Q+
Sbjct: 30709 GTVDAILDVEIQD 30721
Score = 81.3 bits (199), Expect = 8e-15
Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%)
Query: 416 FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
F + Q KE T+ F CE S P +V W+ +G V + ++ D H+L +
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2233
Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
L T D+ YSC + + + +L V F L+D V E L+
Sbjct: 2234 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2287
Query: 535 CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
C V + W N ++ T G L ++D ED G Y+ + +
Sbjct: 2288 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2342
Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
KK++ K + KP LQGLSD KV +G V + V+VS
Sbjct: 2343 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2384
Query: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707
E +W+ +G E+Q S+ H H L I+++ ED G Y+ +++G V
Sbjct: 2385 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2443
Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
+V I+ + V G ++ C ++ +V W + + + K
Sbjct: 2444 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2490
Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
+ + LV+ + G Y++++ RV E +C +S+
Sbjct: 2491 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2530
Score = 80.9 bits (198), Expect = 1e-14
Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+ E ++ F E+S P W L+G + R + E+ + G +L L K + +G
Sbjct: 11408 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 11465
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
A NA + L V E+ F+ LKD V E + +C + T
Sbjct: 11466 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 11514
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601
+ W I+ + + HI D+ +D G YT E + S +VT
Sbjct: 11515 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 11572
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
K F+ L D V +G T ++S + V+W N
Sbjct: 11573 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 11611
Query: 662 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
++ S G H L ++EV +D + E+ + A L V E P
Sbjct: 11612 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 11663
Query: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
+F K TA + + C ++ D V W +DG+ + + + + L +
Sbjct: 11664 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 11720
Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837
KK G+Y C C N + A L + +P ++ G
Sbjct: 11721 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 11771
Query: 838 ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889
+ D +G W +GQ D E + K + T + + +A
Sbjct: 11772 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 11827
Query: 890 QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949
+ L ++L + LS D+K ++ F + R+ PKT R + Q
Sbjct: 11828 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 11877
Query: 950 QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007
++ D R L K GT + V + A F + + +G E + K
Sbjct: 11878 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 11931
Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067
+ K ++ + + V + +K N + T + + + + + S + ++L
Sbjct: 11932 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 11990
Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
D + + + G + K + +G P F KLQD E +++LQC++S A
Sbjct: 11991 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 12046
Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ W +GK +K +K ++ +G + ++KAL D G Y C D G + S ++ +
Sbjct: 12047 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 12102
Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
+D E+K RP S+ V+ TE+
Sbjct: 12103 EDR---------EIKLVRPLHSV-EVMETET 12123
Score = 80.9 bits (198), Expect = 1e-14
Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PPKA + ++ + +RAG + L V G W K K++ E + ++ +
Sbjct: 29043 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 29100
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ I + G YTL V+N G++ V + V+D P P G S + TL
Sbjct: 29101 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 29159
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N
Sbjct: 29160 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 29219
Query: 1410 YG-----TSEPSQESELTTVGEKPEEPKD 1433
YG SEP T+ P P++
Sbjct: 29220 YGPGVPVESEPIVARNSFTIPSPPGIPEE 29248
Score = 79.7 bits (195), Expect = 2e-14
Identities = 54/230 (23%), Positives = 92/230 (40%), Gaps = 47/230 (20%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+F +KL+DV+ G ++L+C+VS P ++ W +G + + S ++C++++
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 6800
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
P D G+Y CVA N AG ECS +TV + P+ E T
Sbjct: 6801 SLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQT--------------------- 6839
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
P+ +V G S+ + GT P W K ++
Sbjct: 6840 --------------------------PDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRE 6873
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+ E + + ++L + + G Y+ LV N GS +L V
Sbjct: 6874 LVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV 6923
Score = 79.7 bits (195), Expect = 2e-14
Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
+AG+++++ V G T TW K + +++++ + E + + L I + G Y
Sbjct: 21078 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 21137
Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
L N +G + + V D P PP G ++ S +T SW DGG + +Y +E
Sbjct: 21138 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 21197
Query: 1370 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411
+ + + TW ELA T T++ L EY+FRV+A N YG
Sbjct: 21198 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 21240
Score = 79.3 bits (194), Expect = 3e-14
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 1738 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1797
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1272 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1330
Query: 1798 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1331 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382
Score = 79.3 bits (194), Expect = 3e-14
Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%)
Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R
Sbjct: 2066 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2125
Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
LVI V ED +A N +G L V+ AKQL
Sbjct: 2126 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2173
Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199
F +L VV KE M F C+ T P +V W K +
Sbjct: 2174 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2212
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
+ + + + L I ++ D Y+C++V +A+L ++G A
Sbjct: 2213 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2268
Query: 260 FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
FV+E + E+ ++S E+ + +E + K + +RG +
Sbjct: 2269 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2328
Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363
+ E K +CK + P +LQ S + VQ E + GV
Sbjct: 2329 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2387
Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420
G+E +P+ + L +D+ + A IP G S S
Sbjct: 2388 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2446
Query: 421 QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
+K+ ++ C+VS V W+L + + + ++ L +
Sbjct: 2447 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2505
Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
+ D G Y G++ + L VE++ ++ L+D E Q+ V +
Sbjct: 2506 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2554
Query: 536 SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
+ + + + W + I+ + + + +L + + + +D G YT A G+
Sbjct: 2555 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2609
Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
S +TV A SKP L+D V + + +V+ NP
Sbjct: 2610 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2648
Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+ WL +G + + + E G + L I +D G YT + S +T A L V
Sbjct: 2649 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2704
Query: 713 QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
+ I K +++T + Q + + + V W+++G L
Sbjct: 2705 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2747
Score = 79.0 bits (193), Expect = 4e-14
Identities = 59/265 (22%), Positives = 102/265 (38%), Gaps = 48/265 (18%)
Query: 1074 DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL 1133
+ CK + +D S + P F +KL D+ GK++ LQ + P +++W
Sbjct: 7468 EYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFK 7527
Query: 1134 N-GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
+ G+ ++ + I +S ++ ++ + P + G Y C KNDAG EC ++V +
Sbjct: 7528 DKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE--- 7584
Query: 1193 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1252
P I++ PE KV G
Sbjct: 7585 --------------------------------------------PATIVEKPESIKVTTG 7600
Query: 1253 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1312
++ L V GT ++ W K K++ K+ S L I+ G Y+ V
Sbjct: 7601 DTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEV 7660
Query: 1313 ENKLGSRQAQVNLTVVDKPDPPAGT 1337
+N +G +L V D+ PP+ T
Sbjct: 7661 QNPVGKDSCTASLQVSDRTVPPSFT 7685
Score = 79.0 bits (193), Expect = 4e-14
Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471
P+F ++ + V+F ++ P+P V W+ G ++ + + D G +
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 31749
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528
L + T D Y+ A N G+ SC L V + P F +L + EG
Sbjct: 31750 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 31809
Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584
Q + V G P P + W +GQP+ + G+ LHI+D LPED G Y
Sbjct: 31810 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 31869
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEY 611
A N G SC A + V E+ +K E+
Sbjct: 31870 ATNTAGSTSCQAHLQV-ERLRYKKQEF 31895
Score = 78.6 bits (192), Expect = 5e-14
Identities = 67/283 (23%), Positives = 111/283 (39%), Gaps = 60/283 (21%)
Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1151
+ Q P+F ++L+DV G ++ C +S P ++ W +GK LK + + S +
Sbjct: 8051 QEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDN 8110
Query: 1152 LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP 1211
+++I K G Y C A N G A S ++ + +E P R L
Sbjct: 8111 TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL-----TEGKNPPFFDIR-----LA 8160
Query: 1212 PVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
PV DA V GES + VTGTQPI +W
Sbjct: 8161 PV-----DAVV-----------------------------GESADFECHVTGTQPIKVSW 8186
Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
K ++I+ ++ EN + LT+L + G YT N++G L + ++
Sbjct: 8187 AKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERL 8246
Query: 1332 DPPAGTPCASD----------------IRSSSLTLSWYGSSYD 1358
PP+ T S+ S +T++WY ++ +
Sbjct: 8247 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIE 8289
Score = 78.6 bits (192), Expect = 5e-14
Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)
Query: 1225 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276
+P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K
Sbjct: 14664 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 14721
Query: 1277 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310
++QE E + ++NS+ G S+L + + + G Y +
Sbjct: 14722 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 14781
Query: 1311 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370
VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E
Sbjct: 14782 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 14840
Query: 1371 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
D + W + +T R ++V L+ EY FRVRA N +G P L V +
Sbjct: 14841 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 14898
Query: 1428 PEEPKD 1433
P P D
Sbjct: 14899 PFGPPD 14904
Score = 78.2 bits (191), Expect = 7e-14
Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%)
Query: 36 ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94
I P +++ + EG A E +V V W+ N + I R + ++GT LVI+
Sbjct: 2448 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2505
Query: 95 AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154
H D G Y G + L+VE
Sbjct: 2506 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2533
Query: 155 IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214
K L + E Q F +++ V W + ++PS++ +
Sbjct: 2534 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2585
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272
+ L + + +DD G YT +G+ S +L++ G + ++ +T A + +
Sbjct: 2586 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2640
Query: 273 KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329
EV N SK L + + N S G A K+ + K S
Sbjct: 2641 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2700
Query: 330 RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378
+ + ++KT ++T+ + P G+ GV+ S E+
Sbjct: 2701 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2760
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
+ + + + V R + + K KP+ EN TV F VS
Sbjct: 2761 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2819
Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
P V WF + ++ + + + H L L D+G Y+ GQL C
Sbjct: 2820 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2873
Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
L VE L + + +K+ V E + +C V VP + WL NG I+ +
Sbjct: 2874 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2925
Query: 559 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
+ + +L I + ED YT + N QVS + VT
Sbjct: 2926 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2967
Query: 616 APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674
PI + L D+ + +T V V+ WL NG EI+ ++ +
Sbjct: 2968 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 3019
Query: 675 GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
HSL I+ V D YT AG+ + A L V+ H F + +
Sbjct: 3020 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3071
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
+ + C ++ +P TV W++D + L + T ++ + + V L++ + AG+Y +
Sbjct: 3072 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3129
Query: 795 LLKNRV 800
+ V
Sbjct: 3130 VAGGNV 3135
Score = 78.2 bits (191), Expect = 7e-14
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)
Query: 1228 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
P T A + P + F + +V + + TG T TW K ++ + +K
Sbjct: 13383 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 13442
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI
Sbjct: 13443 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 13501
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404
S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V
Sbjct: 13502 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 13561
Query: 1405 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433
A N G EP+ E ++T P+ P++
Sbjct: 13562 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 13593
Score = 78.2 bits (191), Expect = 7e-14
Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
PA ++L V ++ +L + D + I L K + F + + + ++
Sbjct: 28546 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 28605
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
E+ + + ++ AKNDAG +E P+ + V+
Sbjct: 28606 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 28637
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+K+ T + Q+I +AG + ++G TW +
Sbjct: 28638 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 28687
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G
Sbjct: 28688 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 28747
Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396
S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L
Sbjct: 28748 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 28807
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
EY FRV + N +G S+P + + + + E P P
Sbjct: 28808 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 28840
Score = 77.4 bits (189), Expect = 1e-13
Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%)
Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
S+DVV + G + A P F +KP Q++ E +V F C+V G PKP V W
Sbjct: 1059 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1118
Query: 451 GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509
G P+ + + G L + D+G Y+ N G+ S S +L +E
Sbjct: 1119 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1177
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567
+ S +L V FV + V G P + + + ++ +A+
Sbjct: 1178 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1233
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625
+ ++ + + + E + ++ T E+ + + + + ++ S+ F
Sbjct: 1234 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1293
Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683
+ + ++++G VT ++SG P P++ W +G I+ E + F Q G + SL I
Sbjct: 1294 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1352
Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732
V PED G YT A N G L V+ P +I PRSV+
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1412
Query: 733 S 733
S
Sbjct: 1413 S 1413
Score = 77.4 bits (189), Expect = 1e-13
Identities = 62/218 (28%), Positives = 93/218 (42%), Gaps = 32/218 (14%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
E P FI P ++ G A + +V G PE +++W++ + S + + S
Sbjct: 7018 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFK-NNVAS 7076
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
LVI+ V D G+Y+C+A N GA + L ++ A++L
Sbjct: 7077 LVINKVDHSDVGEYSCKADNSVGAVASSAVLVIK---ARKL------------------- 7114
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
PP FA KL V G F C+I G QV+W K V L+ A + S
Sbjct: 7115 ---------PPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTS 7165
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
+ + L+I +Q +G Y C N G AS SA+L
Sbjct: 7166 FVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 7203
Score = 77.0 bits (188), Expect = 2e-13
Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI
Sbjct: 23230 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 23289
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++ +D G Y N GQ S ++ D P + K P
Sbjct: 23290 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 23332
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
D + + PP QI + ++ T W
Sbjct: 23333 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 23376
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332
+ + +KV + G++ + + EN+ G A + +V +P
Sbjct: 23377 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 23424
Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385
PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT
Sbjct: 23425 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 23478
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
T F Q+L EY+FRV A N+ G + S+ SE + + P
Sbjct: 23479 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 23524
Score = 76.6 bits (187), Expect = 2e-13
Identities = 66/242 (27%), Positives = 101/242 (41%), Gaps = 22/242 (9%)
Query: 13 SKTSLSVDPSRVDS----MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
+ SLSV+ V S MP+ PA I P ++ EG A+F+ RV G + +V+W+
Sbjct: 3322 TSASLSVEVPEVVSPDQEMPVYP-PAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYS 3379
Query: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
+ I RF T+ L I + ED G YT A+N G T L++E
Sbjct: 3380 KDKKIKPS-RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP-- 3436
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
L +R +E + + P K+ + V G + +F+C+I P
Sbjct: 3437 --------ESILHER-----IEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAP 3483
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
+ W K + S + S+ + LEI D G YTC N G S +A L
Sbjct: 3484 NVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 3543
Query: 249 SI 250
++
Sbjct: 3544 TV 3545
Score = 76.6 bits (187), Expect = 2e-13
Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+
Sbjct: 12825 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 12883
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206
+D Y C ++ +A + + V+ +AP ++ E+ +
Sbjct: 12884 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 12943
Query: 1207 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241
++++ V G + + K + + A P+I
Sbjct: 12944 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 13003
Query: 1242 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301
+D V G+ + + W K + + ++ + + IL A+
Sbjct: 13004 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 13060
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+ G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS
Sbjct: 13061 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 13119
Query: 1362 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418
+ Y +E D KTW LAT R+ S F V L EY FRV A N GT EP +
Sbjct: 13120 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 13178
Query: 1419 SELTTVGEKPEEPKDEVEVSDDD 1441
K + P + V+ D
Sbjct: 13179 DNPVEARSKYDVPGPPLNVTITD 13201
Score = 76.3 bits (186), Expect = 3e-13
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 1721 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1779
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 905 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964
Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 965 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023
Query: 1840 ATCTAELIVETMEEGEGE 1857
+ + L V+ EE E E
Sbjct: 1024 VSTSCYLAVQVSEEFEKE 1041
Score = 76.3 bits (186), Expect = 3e-13
Identities = 62/234 (26%), Positives = 97/234 (41%), Gaps = 48/234 (20%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+F + L+ + G LLQC+VS P I W + K ++++K L + SL + I
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEI 3890
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
D G Y+CV N+ G +C C T
Sbjct: 3891 FSFNSADVGEYECVVANEVG--KCGCMAT------------------------------- 3917
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+K+ PP ++ +D G++V L V G++PI+ TWMK ++
Sbjct: 3918 --HLLKE------------PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEV 3963
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
I+E +K+ S + L I + G YT L EN+ GS Q V +V +P
Sbjct: 3964 IREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS-QTSVGELIVKEP 4016
Score = 75.9 bits (185), Expect = 3e-13
Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)
Query: 1052 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105
N++P ++LK +E + D + + + +A G ++ + SE+ P +
Sbjct: 14335 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 14394
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D
Sbjct: 14395 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 14454
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
G+Y +N G A S V V P ++K+ SD T
Sbjct: 14455 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 14496
Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
PP+ G PI ++ R++ ++
Sbjct: 14497 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 14528
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343
V + EN T+ + + NK+G + N + P P P ++
Sbjct: 14529 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 14588
Query: 1344 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395
+ ++T++W YDGGS + Y IE + WK C ++ + L
Sbjct: 14589 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 14645
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442
EY+FRVRA N G SEPS+ + T + + PK +EV DE
Sbjct: 14646 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 14696
Score = 74.7 bits (182), Expect = 8e-13
Identities = 69/308 (22%), Positives = 120/308 (38%), Gaps = 73/308 (23%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F V + ++ L+C++S PP ++W + + L+++K ++ + S+ I
Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHI 5576
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
D G Y C A+N+ G C C
Sbjct: 5577 LNVDTSDIGEYHCKAQNEVGSDTCVC---------------------------------- 5602
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
TVK K PP+ + V AGE EL + G QPI W+K +++
Sbjct: 5603 ---TVKLKE----------PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEE 5649
Query: 1278 -IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL------TVVDK 1330
I+ESE++++ EN + L A + G Y ++N G R+ L +V+K
Sbjct: 5650 VIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEK 5709
Query: 1331 PDP---PAGTPCASDIR---SSSLTLSWYG-------------SSYDGGSAVQSYSIEIW 1371
P G C + + + L++ WY S Y+ S+++ S+E
Sbjct: 5710 AGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQ 5769
Query: 1372 DSANKTWK 1379
D+ T++
Sbjct: 5770 DAGTYTFQ 5777
Score = 74.3 bits (181), Expect = 1e-12
Identities = 59/236 (25%), Positives = 93/236 (39%), Gaps = 29/236 (12%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
PA LQD +EG+ QC+VS + W K +K ++F ++Q + I
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+A PED G Y VA N GQ + ++++ P+S L + E
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLE----------------APESILHERIEQE 3447
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+ +K P K E +V G + ++ + W K ++
Sbjct: 3448 IEMEMKAAPVIKRKI------------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE 3495
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
I ES+ + +S+ S L IL + CG YT N+ GS LTV + P
Sbjct: 3496 IYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 3551
Score = 73.9 bits (180), Expect = 1e-12
Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
VKE Q V F CEV+ + WF + I + +D + L + A D
Sbjct: 12651 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 12708
Query: 485 YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
Y+ + +N +G+ + + L VE + V P LKD +E + C V V
Sbjct: 12709 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 12763
Query: 544 RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
+ W NG+ + + H I+D D G Y VT
Sbjct: 12764 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 12807
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
+ KS +E L+ AP++ F++ L D V + + Q+S V W NG
Sbjct: 12808 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 12859
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719
EI+E + + FE+ G+ H L I++ +D Y C + +++A L V+E P +
Sbjct: 12860 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 12915
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
+P P+ + + G V+ + D V WLR+ + + H +++ + L
Sbjct: 12916 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 12968
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVS 808
+ ++P G+Y + K++ +++
Sbjct: 12969 QICDIKPRDQGEYRFIAKDKEARAKLELA 12997
Score = 73.9 bits (180), Expect = 1e-12
Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V+V G L + +S P + + +G LK T ++++++++ D G
Sbjct: 26486 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 26545
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224
Y+ A N +G + + V D P P V+ TE T+K
Sbjct: 26546 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 26591
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+P PK + + I+ ++ S ++ +V+ T + T MK K E+
Sbjct: 26592 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 26641
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344
+EN + + + S V L P PP+ TP +++
Sbjct: 26642 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 26682
Query: 1345 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402
S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F
Sbjct: 26683 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 26742
Query: 1403 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
RV A N G +PS SE + E P++ V ++D + + ++ + K++
Sbjct: 26743 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 26801
Query: 1463 FYDIEER 1469
Y +E R
Sbjct: 26802 -YIVERR 26807
Score = 73.2 bits (178), Expect = 2e-12
Identities = 87/395 (22%), Positives = 147/395 (37%), Gaps = 84/395 (21%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+F +KL+ + +G + L+C V+ P +I W + + + ++ S + + I
Sbjct: 4675 PSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEI 4734
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+ D G Y C A N AG +CS +TV +
Sbjct: 4735 SQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE---------------------------- 4766
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
PP ++ P+ Q V V+L V GT P+T W K K+
Sbjct: 4767 -------------------PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKE 4807
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV------VDKP 1331
+ V + + L + AA+ G Y + N +G+ ++ L V + KP
Sbjct: 4808 LHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKP 4867
Query: 1332 DP------PAGTPCASDIRSS-SLTLSWYGSSYDGG--SAVQSYSIEIWDSANKTWKELA 1382
P T I + + +SWY DG +A+Q + I D LA
Sbjct: 4868 SPVLVLRNGQSTTFECQITGTPKIRVSWY---LDGNEITAIQKHGISFIDG-------LA 4917
Query: 1383 TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL----TTVGE-KPEE--PKDEV 1435
T F + ++ + A N GT+ S E ++ T + E KP E +V
Sbjct: 4918 T-----FQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDV 4972
Query: 1436 EVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERL 1470
E+ + P + + N E + S Y + +R+
Sbjct: 4973 ELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRV 5007
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328
R+++ ++ +++ G+ L + ++ + + EN+ G S + T +
Sbjct: 30267 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 30326
Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386
+ P+PP+ P D+ SS++LSW DGGS V Y IE +++ W +
Sbjct: 30327 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 30386
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437
T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+
Sbjct: 30387 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 30439
Score = 72.4 bits (176), Expect = 4e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)
Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++
Sbjct: 15098 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 15153
Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347
N S+L I A ++ G Y + N GS+ A + V D P P R
Sbjct: 15154 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 15213
Query: 1348 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407
L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A
Sbjct: 15214 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 15272
Query: 1408 NVYGTSEPSQESELTTV 1424
N +G P + + V
Sbjct: 15273 NKFGCGPPVEIGPILAV 15289
Score = 72.0 bits (175), Expect = 5e-12
Identities = 59/235 (25%), Positives = 95/235 (40%), Gaps = 48/235 (20%)
Query: 1098 PAFKQKLQDVHVA-EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
P F +KL+ VA +G+ + L+C++S P + W N L + +S S+ ++
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLT 6423
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
I +A ED G Y C A N G A CS +TV KAP + +++P
Sbjct: 6424 INEASAEDSGDYICEAHNGVGDASCSTALTV---------KAPPVFTQKPS--------- 6465
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
P A+ G V L +++GT P W+K RK
Sbjct: 6466 ---------------PVGAL--------------KGSDVILQCEISGTPPFEVVWVKDRK 6496
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
Q++ S+ K+ + + L IL G Y N++GS ++ + P
Sbjct: 6497 QVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP 6551
Score = 72.0 bits (175), Expect = 5e-12
Identities = 103/475 (21%), Positives = 169/475 (35%), Gaps = 98/475 (20%)
Query: 993 AENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKP--MGNAKPAETL--K 1048
A NG A A V++ P+ +PS PVG K ++ + + P E + K
Sbjct: 6439 AHNGVGDASCSTALTVKAP-PVFTQKPS----PVGALKGSDVILQCEISGTPPFEVVWVK 6493
Query: 1049 PMGNAKPDENLKSASKE--------ELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAF 1100
+ + K SK L+ + +CK + +D S P F
Sbjct: 6494 DRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRF 6553
Query: 1101 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIEK 1159
+KL D G + L+ V P +++W + G+ ++ ++ +S ++ ++ +
Sbjct: 6554 VKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGS 6613
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
+ G Y C KNDAG ECS +TV +
Sbjct: 6614 PEASNSGKYICQIKNDAGMRECSAVLTVLE------------------------------ 6643
Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
P +II+ PE V G L VTGT ++ W K +++
Sbjct: 6644 -----------------PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELS 6686
Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1339
+ + L I A G Y+ V+N +G V++ V D+ PP+
Sbjct: 6687 ADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRK 6746
Query: 1340 ASDIR---------------SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
D+ S+ +++ W+ DG V + S N C
Sbjct: 6747 LKDVNAILGASVVLECRVSGSAPISVGWF---QDGNEIVSGPKCQSSFSEN-------VC 6796
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKP--EEPKDEVEV 1437
+ N+ L P + A NV G+ E S + TV E P E+ D VEV
Sbjct: 6797 ---TLNLSLLEPSDTGIYTCVAANVAGSDEC---SAVLTVQEPPSFEQTPDSVEV 6845
Score = 71.6 bits (174), Expect = 7e-12
Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
+D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T
Sbjct: 27164 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 27222
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+
Sbjct: 27223 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 27276
Score = 71.2 bits (173), Expect = 9e-12
Identities = 63/276 (22%), Positives = 108/276 (39%), Gaps = 48/276 (17%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFI--LPPRNLCIKEGATAKFEGRVRGY 59
G AS+ K S S + + E P FI L P + +K+ ++E ++ G
Sbjct: 7280 GQYTCYASNIAGKDSCSAQ------LGVQEPPRFIKKLEPSRI-VKQDEFTRYECKIGGS 7332
Query: 60 PEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
PE +V W+++ I +F + + L +H + ED G YTCEA N +G+ +
Sbjct: 7333 PEIKVLWYKDETEIQESSKFRMSF-VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 7391
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
L V+ PP F K + +G
Sbjct: 7392 SLKVKE----------------------------------PPIFRKKPHPIETLKGADVH 7417
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
C++ G P V+W K L+ + + +N + + I V+ D+G Y C N
Sbjct: 7418 LECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDV 7477
Query: 240 GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEV 275
G + ++++ A FV++ ++ V KEV
Sbjct: 7478 GSDTCVGSIALK----APPRFVKKLSDISTVVGKEV 7509
Score = 71.2 bits (173), Expect = 9e-12
Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324
P T W++ K + +V+ N K + +L EN G + +
Sbjct: 13924 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 13972
Query: 1325 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
+ + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W
Sbjct: 13973 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 14032
Query: 1381 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437
+A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV
Sbjct: 14033 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 14092
Score = 70.9 bits (172), Expect = 1e-11
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P
Sbjct: 1526 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1584
Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P + W +N I + ++ G +G +L I + +D YT A N +G
Sbjct: 1585 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1643
Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
++ VE FA+ + + G +AP +E +G + P
Sbjct: 1644 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1703
Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
F KL + +K F C++T G P V WL PL+ + R+ + + G L+
Sbjct: 1704 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1763
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
D G+ TC N G SA L ++ +S V E++
Sbjct: 1764 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1805
Score = 70.9 bits (172), Expect = 1e-11
Identities = 60/249 (24%), Positives = 94/249 (37%), Gaps = 46/249 (18%)
Query: 1098 PAFKQKLQD-VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
P+F ++L + V EG L+ +V+ P T+ W N ++ T ++ + + +
Sbjct: 8249 PSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQ 8308
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
+ KA D GLY C NDAG A C+ + +
Sbjct: 8309 VRKAGMNDAGLYTCKVSNDAGSALCTSSIVI----------------------------- 8339
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
K P K PP Q V GE V+L V G++PI W+K +
Sbjct: 8340 ------------KEPKK---PPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGR 8384
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD-PPA 1335
+I+ S+ + + L + + G Y N GS + +T+ DKP PA
Sbjct: 8385 EIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPA 8444
Query: 1336 GTPCASDIR 1344
A D R
Sbjct: 8445 TKKAAVDGR 8453
Score = 70.9 bits (172), Expect = 1e-11
Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G
Sbjct: 27573 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 27632
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y + N C++ V P + T P K + P
Sbjct: 27633 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 27663
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283
I+F E + +SV L V G ITC ++ R+ Q +
Sbjct: 27664 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 27705
Query: 1284 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337
M + + K+ L E+ + + EN+ G Q V+ +V K P PP G
Sbjct: 27706 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 27762
Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395
P ++ S ++L+W YDGGS V + +E + + W+++ T + L+
Sbjct: 27763 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 27822
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455
+Y+FRV A N G S PS S+ T+ P +P + D V T+T+
Sbjct: 27823 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 27874
Query: 1456 TEQKVSD------FYDIEERLGSGKF 1475
+ D Y IE+R G+ ++
Sbjct: 27875 WNPPLRDGGSKIVGYSIEKRQGNERW 27900
Score = 70.5 bits (171), Expect = 1e-11
Identities = 51/205 (24%), Positives = 79/205 (38%), Gaps = 32/205 (15%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106
G FE R+ G QV+W+++G + L + +L I + G+Y C
Sbjct: 7130 GFPVAFECRINGSEPLQVSWYKDGVLLKDDAN-LQTSFVHNVATLQILQTDQSHIGQYNC 7188
Query: 107 EATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATK 166
A+N G + +L + E PP F K
Sbjct: 7189 SASNPLGTASSSAKLILSEH-------------------------------EVPPFFDLK 7217
Query: 167 LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226
V + G+ G F C +TG ++TW K N ++P ++ L + V +
Sbjct: 7218 PVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKG 7277
Query: 227 DVGVYTCLVVNGSGKASMSAELSIQ 251
D G YTC N +GK S SA+L +Q
Sbjct: 7278 DAGQYTCYASNIAGKDSCSAQLGVQ 7302
Score = 70.5 bits (171), Expect = 1e-11
Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A + I+ L+V +D F +P +++ + E A+FE + E
Sbjct: 11464 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 11512
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W + I S +F + + LVI+ +D G YT E
Sbjct: 11513 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 11557
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
VEG K R + KF + L VKEG+ F
Sbjct: 11558 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 11594
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C+++ + V W K + L S V +S + LE+ V DD+ V +
Sbjct: 11595 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 11649
Query: 242 ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283
S +A+L + D + + A D V K+V K+
Sbjct: 11650 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 11709
Query: 284 KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337
K D L K K +G G+ AN + R K+E P + V
Sbjct: 11710 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 11764
Query: 338 LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397
+ I L V + + G + + E Q G+ + +V +
Sbjct: 11765 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 11823
Query: 398 AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456
AAN + + P P S +V E KF CEVS PK W L+GT
Sbjct: 11824 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 11880
Query: 457 QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516
+ E+ +D H + + A D Y A + +L + + F
Sbjct: 11881 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 11931
Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576
+ LKD E + V + + R+ W N Q + RS + +QD
Sbjct: 11932 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 11982
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
T+ L+ + Q+ A SE L V P F L D ++
Sbjct: 11983 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 12031
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
+V + ++S P V W +G EI+ S++ + G + L +++ D G YTC+
Sbjct: 12032 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 12090
Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
G +T L +++ + + SV ++ I+ D +W
Sbjct: 12091 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 12141
Query: 757 DGKALCKDTGHFEVLQNEDVFTLVL 781
G+AL + T E+ + + +LVL
Sbjct: 12142 KGEALLQ-TPDCEIKEEGKIHSLVL 12165
Score = 70.5 bits (171), Expect = 1e-11
Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L + V G K+ L V+ P I WT LK K I + +V+I +
Sbjct: 13697 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 13756
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y A N G+A +V V D P PP +D T +
Sbjct: 13757 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 13798
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
PP+ +I + +++ E W K ++++
Sbjct: 13799 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 13842
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339
K T L +E+ + + EN G Q + +T + DPP G P
Sbjct: 13843 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 13889
Query: 1340 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396
SDI ++TL+W DGGS + Y +E D W + T++ V+ L
Sbjct: 13890 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 13949
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
+Y+FRV A N+ G +PS+ +E + + + P
Sbjct: 13950 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 13984
Score = 70.1 bits (170), Expect = 2e-11
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1815
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 69.7 bits (169), Expect = 3e-11
Identities = 51/223 (22%), Positives = 89/223 (39%), Gaps = 38/223 (17%)
Query: 26 SMPLTEAPAFI--LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
++ + E P+F+ + P L + G +A+ +++G P QVTW +N + ++ +
Sbjct: 3730 TVTVREPPSFVKKVDPSYLMLP-GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYF 3788
Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
+ L I V ED G Y+CEA N G+ + E+ ++
Sbjct: 3789 -VNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE------------------ 3829
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
PP F L + G C+++G +++W K ++
Sbjct: 3830 ----------------PPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRS 3873
Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
S + + + + LEI N DVG Y C+V N GK A
Sbjct: 3874 SKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMA 3916
Score = 69.3 bits (168), Expect = 3e-11
Identities = 61/269 (22%), Positives = 98/269 (36%), Gaps = 61/269 (22%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+F+Q V V G L + PP + W + L + +S E + + +
Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELEL 6893
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+ P + G Y C+ NDAG A C+ + V +
Sbjct: 6894 FEVQPLESGDYSCLVTNDAGSASCTTHLFVKEP--------------------------- 6926
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
AT K+ A D V G + L TGT PI+ +W+K
Sbjct: 6927 --ATFVKRLA------------------DFSVETGSPIVLEATYTGTPPISVSWIKDEYL 6966
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP------ 1331
I +SE + +E + L IL + E Y+ L+EN+ G + ++V++ P
Sbjct: 6967 ISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPL 7026
Query: 1332 -------DPPAGTPCASDIRSSSLTLSWY 1353
PA C D + + +SWY
Sbjct: 7027 EHVEAVIGEPATLQCKVD-GTPEIRISWY 7054
Score = 69.3 bits (168), Expect = 3e-11
Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)
Query: 1217 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
ESD V + P P TP A+ + + V G S + + + + W
Sbjct: 23410 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 23469
Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
K K I K +N E G + + + EN +G +A N
Sbjct: 23470 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 23518
Query: 1332 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387
DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T
Sbjct: 23519 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 23578
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438
F V L D Y+FRV A N G S+PS + T ++ E P +D + V+
Sbjct: 23579 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 23638
Query: 1439 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495
+ E D + T + + +IEE F+ L+ K ++ G++
Sbjct: 23639 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 23698
Query: 1496 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554
+A + ++ + +++ P+ VQ EK ++ + GG + E
Sbjct: 23699 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 23758
Query: 1555 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598
E + E + +++ EG EY+ + IM VNK G
Sbjct: 23759 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 23800
Score = 69.3 bits (168), Expect = 3e-11
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Query: 1306 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357
GC Y + EN G ++ DP P P D +++T++W +
Sbjct: 26050 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 26109
Query: 1358 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS
Sbjct: 26110 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 26169
Query: 1417 QESELTTVGEKPEEPKDEVE 1436
S+ E+ EEP +++
Sbjct: 26170 DSSDPQIAKEREEEPLFDID 26189
Score = 69.3 bits (168), Expect = 3e-11
Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%)
Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
E S ++EVT + E + + + A + + S+ + R SP +
Sbjct: 32229 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 32288
Query: 311 --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368
S+PQP E + ++ + SP TP + PR+P SP
Sbjct: 32289 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 32323
Query: 369 EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423
ER R A F +R + + K + R+ + Q+ P+ + +S
Sbjct: 32324 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 32383
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
V Q +F V P EV W+ G ++ + I +G L +L T DSG
Sbjct: 32384 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 32442
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542
TY +N +G+ S TL V G D+ S R V
Sbjct: 32443 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 32480
Query: 543 PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
PR + + YA S+ EA + ++ + E + + +A ++ +A
Sbjct: 32481 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 32540
Query: 597 WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
++ EK ++RK + L A L + V +G + G P P V
Sbjct: 32541 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 32592
Query: 655 IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714
WL G + S + + I V D G Y+ NS G+ + LT+Q+
Sbjct: 32593 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 32652
Score = 69.3 bits (168), Expect = 3e-11
Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L AP L R+ + G +F V+ P +V W+ NG + + G
Sbjct: 32370 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 32428
Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
+L I H +D G Y T + T G R V EL
Sbjct: 32429 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 32488
Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
T ++A K+ + S ++ + + ETR S+
Sbjct: 32489 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 32547
Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
+ TK + V EG+ RFSC G P P VTWL+ L SAR
Sbjct: 32548 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 32607
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
V+ EI V D G Y+ +V N GK L+IQ ++ V E KA
Sbjct: 32608 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 32660
Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
S R V S E ++ S EA K SP+ P P + + E +
Sbjct: 32661 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 32711
Query: 328 SPRTAP 333
P +AP
Sbjct: 32712 LPVSAP 32717
Score = 68.9 bits (167), Expect = 4e-11
Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)
Query: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
P KL V V G + L+ V P + WT + T+ + +
Sbjct: 18201 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 18260
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213
S+ KA D G Y A N AG V V D P N K ++ S R
Sbjct: 18261 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 18312
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
TV P P+ + I++ E +++ W
Sbjct: 18313 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 18345
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330
+ + G+ +T L E+ + + ENK+G+ + V+ K
Sbjct: 18346 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 18393
Query: 1331 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
PDPP T + + +T+ W YDGG ++ Y +E + + W + +
Sbjct: 18394 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 18449
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
VQ+LLPDHEY+FRV+A N G EPS S V + P EP
Sbjct: 18450 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 18496
Score = 68.6 bits (166), Expect = 6e-11
Identities = 57/219 (26%), Positives = 88/219 (40%), Gaps = 35/219 (15%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P+FI +++ GA+ E RV G V W ++G I SG + +L
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFS-ENVCTLN 6799
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
+ + D G YTC A N +G+ + + LTV+
Sbjct: 6800 LSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE--------------------------- 6832
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212
PP F V V G F+ I G P +V W KG+ L P ++S +
Sbjct: 6833 -------PPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLE 6885
Query: 213 NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
+ + LE+ V + G Y+CLV N +G AS + L ++
Sbjct: 6886 DFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924
Score = 68.6 bits (166), Expect = 6e-11
Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI
Sbjct: 25395 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 25454
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++A ED G Y+ N AG + V D P PP
Sbjct: 25455 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 25496
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+ + PP+ QI + ++K + + TW +
Sbjct: 25497 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 25540
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333
+ + +K+ GS+ + + EN+ G + VV + P
Sbjct: 25541 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 25588
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386
P GTP S++ ++W DGGS V Y +E +W ANK
Sbjct: 25589 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 25643
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446
T V L Y++RV A N+ G + S+ E P +P + EV++ K
Sbjct: 25644 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 25702
Query: 1447 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475
+ + + K++ + L G++
Sbjct: 25703 LKWSKPHYDGGAKITGYIVERRELPDGRW 25731
Score = 68.6 bits (166), Expect = 6e-11
Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)
Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+
Sbjct: 33127 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 33186
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194
++ S+ I A D G Y AKN GQ + + V + P+ E
Sbjct: 33187 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 33246
Query: 1195 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235
++++ +M + + ++S + + + + K A + +
Sbjct: 33247 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 33306
Query: 1236 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
+PP+I P D + G+ + + TG TW
Sbjct: 33307 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 33366
Query: 1276 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ +
Sbjct: 33367 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 68.2 bits (165), Expect = 7e-11
Identities = 50/235 (21%), Positives = 84/235 (35%), Gaps = 45/235 (19%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
AP K+K++ + VA G C++ S P W G+ + + + + S+
Sbjct: 3455 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 3514
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
I + D G Y C A N+ G C+ +TV +A
Sbjct: 3515 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEA-------------------------- 3548
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
PP + P+ G++ + VTGT I W K
Sbjct: 3549 -------------------YPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGA 3589
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ S + ++ ++EN L + + G Y+ NK G+ Q L ++DKP
Sbjct: 3590 ALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKP 3644
Score = 68.2 bits (165), Expect = 7e-11
Identities = 48/162 (29%), Positives = 76/162 (46%), Gaps = 12/162 (7%)
Query: 1693 KWQKTGNAVRA-----IGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLE 1747
KW K G + A I +++A + S +G T ++ E S + + L+
Sbjct: 4049 KWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLD 4108
Query: 1748 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
+ P+F+K +R+++ V R DCKI G V WFKD + I S ++I
Sbjct: 4109 R------DIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIA 4162
Query: 1808 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ E G SL I V +D +TC+A NS+G + LIV+
Sbjct: 4163 FVE-GTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ 4203
Score = 68.2 bits (165), Expect = 7e-11
Identities = 60/273 (21%), Positives = 101/273 (36%), Gaps = 63/273 (23%)
Query: 1097 APA-FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
APA F ++L D + +GK L+L+ + PP ++ W NG + ++ ++ +
Sbjct: 7866 APAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAIL 7925
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1215
I + ED G Y C +N +G+ CS Q+ + +
Sbjct: 7926 EIPSSTVEDAGQYNCYIENASGKDSCSAQILILE-------------------------- 7959
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
PP ++ E KV G+S L ++ GT I +W K
Sbjct: 7960 ---------------------PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGD 7998
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
+++ + K+ N + L G Y EN +G A LTV ++ PP+
Sbjct: 7999 TKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPS 8058
Query: 1336 ------------GTPCASDIR---SSSLTLSWY 1353
G P D S +++SWY
Sbjct: 8059 FSRQLRDVQETVGLPVVFDCAISGSEPISVSWY 8091
Score = 67.4 bits (163), Expect = 1e-10
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 1737 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 67.4 bits (163), Expect = 1e-10
Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154
P Q+LQ V V GK +S P I W + L T KF+ QE +L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3298
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
+ +A PED +Y C AKND G A S ++V+ PE+ S P +P
Sbjct: 3299 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3341
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
PP II +D G+ +V+GT + +W
Sbjct: 3342 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3380
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
K+I+ S ++ E+ +L I A E G YT + N +G + NL++
Sbjct: 3381 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Score = 67.0 bits (162), Expect = 2e-10
Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
++ + V G + + P T WT +G +KT + + + ++I+ L
Sbjct: 17517 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 17576
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y+ N AG + +TV D P P + + T T+
Sbjct: 17577 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 17624
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
+P P P I E Q R + +G V+
Sbjct: 17625 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 17655
Query: 1284 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336
+GS T L GC + + ENK+G + V K P P G
Sbjct: 17656 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 17708
Query: 1337 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390
P +DI ++ T+SW DGGS + Y +E W NKT F
Sbjct: 17709 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 17763
Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
V L + Y+FRV A N+ G S+PS S+
Sbjct: 17764 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 17793
Score = 67.0 bits (162), Expect = 2e-10
Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224
A+N +G + ++ V D P + K +M S R S P L G+E +
Sbjct: 19367 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 19426
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
K P A +V+ T PIT ++ K I+ E+
Sbjct: 19427 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 19459
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340
+ + ENK G + K DPP P
Sbjct: 19460 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 19496
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
S+I +T+SW + DGGS + Y +E ++ W ++ + L
Sbjct: 19497 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 19556
Query: 1399 EYKFRVRAINVYGTSEPSQESE 1420
EY+FRV AIN G +PS S+
Sbjct: 19557 EYEFRVTAINKAGPGKPSDASK 19578
Score = 66.6 bits (161), Expect = 2e-10
Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 48/235 (20%)
Query: 1098 PAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
P F +K V V G+ +CQ++ P + W L+G + + +S L +
Sbjct: 4861 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQ 4920
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
I A E+ G Y C A+NDAG A CS ++ V + P T E+K
Sbjct: 4921 ISGARVENSGTYVCEARNDAGTASCSIELKVKEPP----TFIRELK-------------- 4962
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
P +++++ + VEL +VTGT P TW+K +
Sbjct: 4963 --------------------PVEVVKYSD---------VELECEVTGTPPFEVTWLKNNR 4993
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+I+ S+ + + + L I G Y +V N+ GS + + + P
Sbjct: 4994 EIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPP 5048
Score = 66.6 bits (161), Expect = 2e-10
Identities = 60/261 (22%), Positives = 98/261 (37%), Gaps = 47/261 (18%)
Query: 1074 DVNCKRGHAGTTDNEK---RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII 1130
+ CK ++ T + K R + + P+F ++L+D+ G + L C+++ P +
Sbjct: 6148 EYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVC 6207
Query: 1131 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
W +G L+ + + S ++ ++ I + G Y C A N G A S ++T
Sbjct: 6208 WYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLT---- 6263
Query: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
+R PK S P P V
Sbjct: 6264 ------------AREPKKS----------------------------PFFDIKPVSIDVI 6283
Query: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310
AGES + VTG QP+ TW K K+I+ + + N L IL + G YT
Sbjct: 6284 AGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTC 6343
Query: 1311 LVENKLGSRQAQVNLTVVDKP 1331
N +G L+V + P
Sbjct: 6344 QATNDVGKDMCSAQLSVKEPP 6364
Score = 66.6 bits (161), Expect = 2e-10
Identities = 50/237 (21%), Positives = 87/237 (36%), Gaps = 43/237 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F +L V G+ +C V+ P + W + + +++ +S + +++
Sbjct: 8153 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTV 8212
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
K D G Y C A N+ G+ C+ Q+ + + +PP
Sbjct: 8213 LKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER------------------LIPPSFTKR 8254
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
TV++ G S +L G+V G+QPIT W K +
Sbjct: 8255 LSETVEETE-------------------------GNSFKLEGRVAGSQPITVAWYKNNIE 8289
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
IQ + + ++ N L + A G YT V N GS ++ + + PP
Sbjct: 8290 IQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 8346
Score = 66.6 bits (161), Expect = 2e-10
Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)
Query: 1083 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134
G +D S+ Q ++ L D+ K L+++ S P ++W+
Sbjct: 26164 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 26223
Query: 1135 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
L+T ++ + S S++IE A D G Y +N A + V V D P
Sbjct: 26224 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 26279
Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254
PP T D T + A + + PE+
Sbjct: 26280 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 26304
Query: 1255 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312
G P+ ++ R + S+ V + N ++L+ + Y V
Sbjct: 26305 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 26353
Query: 1313 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E
Sbjct: 26354 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 26412
Query: 1370 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429
+ K W + A +ST V L + EY FRV A N G S+P + + E+ E
Sbjct: 26413 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 26472
Query: 1430 EPKDEVE 1436
P+ +++
Sbjct: 26473 PPEIDMK 26479
Score = 66.2 bits (160), Expect = 3e-10
Identities = 60/253 (23%), Positives = 98/253 (38%), Gaps = 44/253 (17%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+ + E P F+ P++ + + + V G + W ++ + + SG +
Sbjct: 4762 LTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDT 4821
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
T SL + A D G Y C+ +N G L F K+
Sbjct: 4822 ST-SLELFAAKATDSGTYICQLSNDVGTATSKATL-----FVKE---------------- 4859
Query: 147 PAVETRPSIWGECPPKFATKLGRVVV-KEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
PP+F K V+V + GQ F C+ITG P+ +V+W +
Sbjct: 4860 -------------PPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQ 4906
Query: 206 RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
+ +S +G+ +I G ++ G Y C N +G AS S EL ++ +F+RE K
Sbjct: 4907 KHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK----EPPTFIRELK 4962
Query: 266 ATN----SDVRKE 274
SDV E
Sbjct: 4963 PVEVVKYSDVELE 4975
Score = 65.9 bits (159), Expect = 4e-10
Identities = 38/113 (33%), Positives = 58/113 (51%), Gaps = 15/113 (13%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P+F + ++ V G +A F+C + G +V W KD + IR +QI Y E+ + L
Sbjct: 8153 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLEN-SAHLT 8211
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAEL--------------IVETMEEGEG 1856
+ V D +YTC AVN +G+ +CTA+L + ET+EE EG
Sbjct: 8212 VLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEG 8264
Score = 65.9 bits (159), Expect = 4e-10
Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 15172
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y A N G + +V V D P P L PV+ T +
Sbjct: 15173 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 15218
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
P+ + + II+ +D K+ T QPI E+E K
Sbjct: 15219 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 15254
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342
+ +T L QE+ + ++ +NK G ++ + VD PP ++
Sbjct: 15255 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 15305
Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400
S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y
Sbjct: 15306 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 15365
Query: 1401 KFRVRAINVYGTSEPS 1416
+FRV+A+N G SEPS
Sbjct: 15366 EFRVKAVNEIGESEPS 15381
Score = 65.9 bits (159), Expect = 4e-10
Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 21535
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A N G A+ V V D P P V S+ V P
Sbjct: 21536 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 21582
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
A + I+Q E ++ W ++Q ++
Sbjct: 21583 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 21613
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346
K+T L E+ + ++ NK G + + V+ PDPP P + I
Sbjct: 21614 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 21669
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+
Sbjct: 21670 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 21729
Query: 1405 RAINVYGTSEPSQES 1419
A N G S PS S
Sbjct: 21730 MAENAAGISAPSPTS 21744
Score = 65.9 bits (159), Expect = 4e-10
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW +
Sbjct: 22016 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 22074
Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q
Sbjct: 22075 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 22134
Query: 1418 ES 1419
S
Sbjct: 22135 LS 22136
Score = 65.9 bits (159), Expect = 4e-10
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T
Sbjct: 29342 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 29400
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K
Sbjct: 29401 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 29454
Score = 65.5 bits (158), Expect = 5e-10
Identities = 54/234 (23%), Positives = 84/234 (35%), Gaps = 44/234 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F +KL+DVH G + +C+++ P + W +G LK + S ++ ++ I
Sbjct: 7116 PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQI 7175
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+ G Y C A N G A S ++ + +
Sbjct: 7176 LQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE-------------------------- 7209
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+PP P + GES VTGT PI TW K ++
Sbjct: 7210 ------------------VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNRE 7251
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
I+ + K+ EN + LT+L + G YT N G L V + P
Sbjct: 7252 IRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPP 7305
Score = 65.5 bits (158), Expect = 5e-10
Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
+AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G
Sbjct: 30926 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 30985
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
L+I +V ++D Y ATN G+ T L VE L
Sbjct: 30986 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 31027
Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
PK +G V G++ +G+P P +TW KG + + V
Sbjct: 31028 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 31076
Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
L +GV + D G Y N G + EL + + R
Sbjct: 31077 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 31130
Query: 269 SDVRKEVTNVISKESKLD 286
SDV ++ N+ E D
Sbjct: 31131 SDVSRDSVNLTWTEPASD 31148
Score = 64.7 bits (156), Expect = 8e-10
Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+ K + G+ L ++ V P I W +G+ LK T + + + + + I
Sbjct: 24312 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 24371
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++ +D G Y A N AG A + V V + P PPV
Sbjct: 24372 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 24413
Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
D + PP QI + +++ T TW
Sbjct: 24414 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 24457
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331
+ + +K+ + G++ + + EN+ G + V+ +P
Sbjct: 24458 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 24505
Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389
PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F
Sbjct: 24506 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 24564
Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
L EY+F+V A N+ G +PS+ SE + + P
Sbjct: 24565 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 24606
Score = 64.7 bits (156), Expect = 8e-10
Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)
Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R
Sbjct: 32538 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 32596
Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
GQ +++ R + + TF I +V D G Y+ N G ++ LT++ +
Sbjct: 32597 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 32654
Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
K + P K+ R +P ET+P+ +
Sbjct: 32655 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 32714
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
PPK L KE + + +C + +VTW K L+ + +G
Sbjct: 32715 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 32772
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
L+I+ + + D G Y C + G + + + Q S + + ++ SD +
Sbjct: 32773 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 32832
Query: 275 VTNVISK 281
+ V K
Sbjct: 32833 ESTVTRK 32839
Score = 64.3 bits (155), Expect = 1e-09
Identities = 52/224 (23%), Positives = 85/224 (37%), Gaps = 33/224 (14%)
Query: 29 LTEAPAFILPPRNLC-IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
+ + PA I+ L + G A E V G PE + W+++G+P+ + ++ +
Sbjct: 4012 IVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFK-NN 4070
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
L ++ D G+YT E +N G+ T V+ + + F+ P
Sbjct: 4071 VAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFT------------VLDRDIAPFFTKP 4118
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
+ G C R CKI G +V+W K + S R
Sbjct: 4119 LRNVDSVVNGTC-------------------RLDCKIAGSLPMRVSWFKDGKEIAASDRY 4159
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
++ G LEI V+ +D G +TC N G S L +Q
Sbjct: 4160 RIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ 4203
Score = 64.3 bits (155), Expect = 1e-09
Identities = 69/307 (22%), Positives = 116/307 (37%), Gaps = 64/307 (20%)
Query: 1054 KPDENLKS------ASKEELKKDVKND--VNCKRGHA-GTTDNEKR--SESQGTAPAFKQ 1102
+ DENL++ A+ + L+ D+ + +C + GT + R + +P F
Sbjct: 6216 RDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDI 6275
Query: 1103 KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALP 1162
K + V G+ +C V+ P I W+ + K ++ ++ G+ + I K
Sbjct: 6276 KPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGK 6335
Query: 1163 EDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATV 1222
D G Y C A ND G+ CS Q++V +
Sbjct: 6336 GDSGQYTCQATNDVGKDMCSAQLSVKE--------------------------------- 6362
Query: 1223 KKKPAPKTPPKAAMPPQIIQFPEDQKV-RAGESVELFGKVTGTQPITCTWMKFRKQIQES 1281
PP+ ++ E KV + GES++L K++G+ I +W + ++ ES
Sbjct: 6363 --------------PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHES 6408
Query: 1282 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP-----DPPAG 1336
+ + + LTI A E G Y N +G LTV P P G
Sbjct: 6409 WKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVG 6468
Query: 1337 TPCASDI 1343
SD+
Sbjct: 6469 ALKGSDV 6475
Score = 64.3 bits (155), Expect = 1e-09
Identities = 31/114 (27%), Positives = 63/114 (55%), Gaps = 7/114 (6%)
Query: 1736 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
E+ +D+ +A + + PYF + + +E V G A CK++G P+ + W+K+
Sbjct: 7004 EAGQDICEALVSVLEP------PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEH 7057
Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+R + +++ + ++ SL+I+ V D +Y+CKA NS+G +A L+++
Sbjct: 7058 TKLRSAPAYKMQF-KNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIK 7110
Score = 64.3 bits (155), Expect = 1e-09
Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VR G+++ + +V G TW K K + + + + +L I A + G Y
Sbjct: 17920 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 17979
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ +N G Q + V+D+P P +++ + T+SW +GGS + ++ +
Sbjct: 17980 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 18038
Query: 1369 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425
E K W +A+ + +LL ++EY FRV A N G P+ E++ +
Sbjct: 18039 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 18097
Query: 1426 -EKPEEPKD 1433
++P EP++
Sbjct: 18098 IDRPGEPEN 18106
Score = 64.3 bits (155), Expect = 1e-09
Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)
Query: 1215 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269
G +S+ V + P P PP PP I+ D SV L K TG PIT
Sbjct: 20161 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 20209
Query: 1270 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
++F R + K K+T L E+ + ++ N G + +
Sbjct: 20210 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 20267
Query: 1328 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
V DP P G P +I +S+TL W YDGG + Y +E D +K+W +
Sbjct: 20268 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 20327
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431
+F V DL+ +Y+FR+RA N G S PS+ +E ++ E P
Sbjct: 20328 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 20376
Score = 63.9 bits (154), Expect = 1e-09
Identities = 67/331 (20%), Positives = 125/331 (37%), Gaps = 69/331 (20%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
+P F ++ + + V + ++L +V+ PP I W + L++ + + L S+
Sbjct: 4392 SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQ 4451
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
I K + D G Y+C N+ G + CS +VT+ +
Sbjct: 4452 ILKFVAADAGEYQCRVTNEVGSSICSARVTLRE--------------------------- 4484
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
PP I+ E G + + G+ PIT TW+K
Sbjct: 4485 --------------------PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSD 4524
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP----- 1331
+I E +++++ N + L + +H G Y +N G ++ L+V +
Sbjct: 4525 EITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEE 4584
Query: 1332 ----DPPAGTPCASDIRSS---SLTLSWY--GSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
D G P ++ S +T W+ G GS Y I + D+ + K ++
Sbjct: 4585 AVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGS---KYKISVTDTVS-ILKIIS 4640
Query: 1383 TCRSTS----FNVQDLLPDHEYKFRVRAINV 1409
T + S F VQ+ + K R+ +++
Sbjct: 4641 TEKKDSGEYTFEVQNDVGRSSCKARINVLDL 4671
Score = 63.9 bits (154), Expect = 1e-09
Identities = 43/163 (26%), Positives = 73/163 (44%), Gaps = 14/163 (8%)
Query: 1693 KWQKTGNAVRA-----IGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLE 1747
KW K G + I +++++ +S K +G T E + DV ++ +
Sbjct: 4611 KWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYT-------FEVQNDVGRSSCK 4663
Query: 1748 A-VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
A + + P F+K ++ ++ ++GS +C + G + WFKDDQ I S ++
Sbjct: 4664 ARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKF 4723
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ D L IS + G D YTC A N G C+ L V+
Sbjct: 4724 SF-HDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 4765
Score = 63.9 bits (154), Expect = 1e-09
Identities = 53/230 (23%), Positives = 85/230 (36%), Gaps = 44/230 (19%)
Query: 1102 QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKAL 1161
+K + V V E + L+C V+ P + W +GK + +++ +S E ++ S I+ +
Sbjct: 5145 EKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVM 5204
Query: 1162 PEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT 1221
+D G Y +ND G + C + V D ++PP T
Sbjct: 5205 KQDSGQYTFKVENDFGSSSCDAYLRVLD------------------QNIPP------SFT 5240
Query: 1222 VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQES 1281
K K G S+ + KV+G+ PI+ W K K+I S
Sbjct: 5241 KKLTKMDKV--------------------LGSSIHMECKVSGSLPISAQWFKDGKEISTS 5280
Query: 1282 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
++ E L + E YT V N G LTV + P
Sbjct: 5281 AKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPP 5330
Score = 63.9 bits (154), Expect = 1e-09
Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
QE C Y + EN+ G Q + V + P PP G D+ +S++LSW +
Sbjct: 23098 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 23156
Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P
Sbjct: 23157 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 23214
Score = 63.5 bits (153), Expect = 2e-09
Identities = 87/403 (21%), Positives = 150/403 (37%), Gaps = 89/403 (22%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ +LV HI+ L+V PA+ +++ +KEG T + P
Sbjct: 8725 GNYRLVCGPHIASAKLTVIE-----------PAWERHLQDVTLKEGQTCTMTCQF-SVPN 8772
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
+ W RNG+ + GR + + L I V ED+G+YTC+ + + + EL
Sbjct: 8773 VKSEWFRNGRILKPQGRHKTEVEHK-VHKLTIADVRAEDQGQYTCKYED----LETSAEL 8827
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
+E P +F ++ +VV E Q F
Sbjct: 8828 RIEAE---------------------------------PIQFTKRIQNIVVSEHQSATFE 8854
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV-VNGSG 240
C+++ VTW KG L S + + + IH V DD GVY+ + + G
Sbjct: 8855 CEVS-FDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRG 8913
Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
+A +AEL + T +++ E+ +S++ ++
Sbjct: 8914 EARSTAELYL----------------TTKEIKLELKPPDIPDSRVPIPTMPIRA------ 8951
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
PP PP L + ++ P ++ T ++ A +V +P+
Sbjct: 8952 ----VPPEEIPPVVAPPIPLLLPTPEEK---KPPPKRIEVTKKAVKKDAKKVVAKPKE-- 9002
Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403
++P E K+P PP P + P + DV SKA +I
Sbjct: 9003 ---MTPREEIVKKPPPP-TTLIPAKAPEI--IDVSSKAEEVKI 9039
Score = 63.5 bits (153), Expect = 2e-09
Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271
S+ TV + P K P P + + +V+ E + G +V G + + W
Sbjct: 22329 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 22387
Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+K K K E G + + + G +G V P
Sbjct: 22388 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 22438
Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389
P G P A + +S+TL W +YDGGS + Y +E + W + + T F
Sbjct: 22439 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 22498
Query: 1390 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432
V L+ DH Y+FRV A N G SEPS+ + T ++ + P+
Sbjct: 22499 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 22542
Score = 63.5 bits (153), Expect = 2e-09
Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+
Sbjct: 26887 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 26946
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
+N G A + +V + D P P + T T+ +P P
Sbjct: 26947 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 26993
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
A + I++ E +V W SEH++ E
Sbjct: 26994 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 27023
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
T + E+ + + NK G + + +VV K P PP G P + I +
Sbjct: 27024 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 27080
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404
S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV
Sbjct: 27081 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 27140
Query: 1405 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439
A+N G S+ SE + P P ++ ++D
Sbjct: 27141 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 27177
Score = 63.2 bits (152), Expect = 2e-09
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383
P P P D SS++L W + DGGS ++ Y +E+ + WK + T
Sbjct: 15704 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 15763
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D
Sbjct: 15764 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 15818
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383
+ KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ +
Sbjct: 17110 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 17168
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432
C T + V L YKFRV A+N G S+P+ E V ++ E P+
Sbjct: 17169 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 17217
Score = 63.2 bits (152), Expect = 2e-09
Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)
Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063
K V +S PLS P L+ K + TL L P+ G AK D + S
Sbjct: 18788 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 18838
Query: 1064 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104
+EE D + + + + G + +K E++G A +Q L
Sbjct: 18839 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 18898
Query: 1105 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
+ + + GKKL ++ V P T W + T+ + + + S + I
Sbjct: 18899 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 18958
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215
+ +D G Y A+N +G +V V DAP PP +
Sbjct: 18959 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 19003
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
++DA P + + I+ E V G+ V VT T +
Sbjct: 19004 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 19054
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
K I E++ +EN G L K+ AQ V +P
Sbjct: 19055 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 19099
Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388
T D + ++W DGGS + Y IE +W AN T RST
Sbjct: 19100 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 19150
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
+ L+ EY FR+ A+N G+S PS+ +E T P +P + EV D
Sbjct: 19151 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 19200
Score = 63.2 bits (152), Expect = 2e-09
Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)
Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G
Sbjct: 31580 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 31638
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C+ N G EL V+G +++ +T+ + +T + E PP+F
Sbjct: 31639 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 31692
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
L G+ RF IT P+P VTW K ++P + + G+ L I
Sbjct: 31693 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 31752
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ V DD YT + N G+ S A+L++
Sbjct: 31753 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 62.8 bits (151), Expect = 3e-09
Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)
Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143
D EK+ + P FK+KL + + +C+++ DP + W +GK L+
Sbjct: 1696 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1750
Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203
+ + E CS+ A D G+ C A N G S + V D E + E +
Sbjct: 1751 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1806
Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263
+ L + E A T K P I+ +PE +V GE+ +VTG
Sbjct: 1807 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1866
Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323
W + I++S+ +V + L I+ + G + EN G + +V
Sbjct: 1867 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1925
Query: 1324 NLTVVDKPD 1332
L + + D
Sbjct: 1926 KLEIQQRED 1934
Score = 62.8 bits (151), Expect = 3e-09
Identities = 54/228 (23%), Positives = 80/228 (35%), Gaps = 35/228 (15%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E P F+ +L G T + VRG VTW + + I G+ + G
Sbjct: 3920 LKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGV 3978
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
L+I V GKYTC A N +G++ EL V+
Sbjct: 3979 AVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKE----------------------- 4015
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
P K + + V G + G P+ + W K PL S +
Sbjct: 4016 -----------PAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYR 4064
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256
+S KN + L+ + D G YT + N G +S ++ D A
Sbjct: 4065 ISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIA 4112
Score = 62.8 bits (151), Expect = 3e-09
Identities = 58/246 (23%), Positives = 97/246 (39%), Gaps = 46/246 (18%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E P+FI + G TA F+ ++G VTW ++ IT D IR T
Sbjct: 4482 LREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITE------DDNIRMT 4535
Query: 89 F-----SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
F SL + + + GKY C+A N +G ++ + L+V+
Sbjct: 4536 FENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK------------------- 4576
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
PA T ++ + V +G K +G + W K L
Sbjct: 4577 --EPATITEEAV-------------SIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTL 4621
Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263
++ +S + + +L+I + D G YT V N G++S A +++ L SF ++
Sbjct: 4622 GSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDL-IIPPSFTKK 4680
Query: 264 TKATNS 269
K +S
Sbjct: 4681 LKKMDS 4686
Score = 62.8 bits (151), Expect = 3e-09
Identities = 57/244 (23%), Positives = 86/244 (35%), Gaps = 35/244 (14%)
Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
V ++ L E P F+ +L + G A+ + + G V W + + + +
Sbjct: 5601 VCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRIT 5660
Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
+ +L + GKY C+ N G R+ L V
Sbjct: 5661 FVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMV-------------------- 5700
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
PAV K G + V G+ CK+ G P+ V W K L
Sbjct: 5701 -LEPAV-------------IVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTS 5746
Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263
S + S N + L I V + D G YT V N GK+S +A + + + SF R
Sbjct: 5747 SQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSD-RAVPPSFTRR 5805
Query: 264 TKAT 267
K T
Sbjct: 5806 LKNT 5809
Score = 62.8 bits (151), Expect = 3e-09
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386
KP PP P DI SS+ LSW YDGG +Q Y +E D + W
Sbjct: 22837 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 22895
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
T+ V+ LL HEY FR+ AIN G E + V EK E P ++++
Sbjct: 22896 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 22946
Score = 62.4 bits (150), Expect = 4e-09
Identities = 53/248 (21%), Positives = 95/248 (38%), Gaps = 47/248 (18%)
Query: 1099 AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158
AF ++L D V GK ++L+ + P ++ W +G + T++ + C + I
Sbjct: 5987 AFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEIL 6046
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
+ D G Y C +N+AG+ C V+ + PP TE
Sbjct: 6047 NSTKRDAGQYSCEIENEAGRDVCGALVSTLE---------------------PPYFVTEL 6085
Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
+ P +AA+ G+SV L +V GT IT +W K ++
Sbjct: 6086 E-----------PLEAAV---------------GDSVSLQCQVAGTPEITVSWYKGDTKL 6119
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
+ + + + N + L G YT EN +G+ ++ + ++ PP+
Sbjct: 6120 RPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFAR 6179
Query: 1339 CASDIRSS 1346
DI +
Sbjct: 6180 QLKDIEQT 6187
Score = 62.4 bits (150), Expect = 4e-09
Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G
Sbjct: 20786 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 20843
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
+ + N +GK S ++++ LD+ +R T T V +TN
Sbjct: 20844 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 20901
Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
I ++ ++ A K C+ G S A N +P ++
Sbjct: 20902 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 20961
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
++P ++ T S+++L P+P+ G ++ E +R + T T
Sbjct: 20962 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 21016
Query: 386 QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425
GL Q + +A R P E + + P+ + + Q++
Sbjct: 21017 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 21076
Query: 426 -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
K +K V G PKP V W +G + +Q + A S L + + DSG
Sbjct: 21077 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 21135
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522
Y TA N G++ T+QV + P F V D
Sbjct: 21136 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 21174
Score = 62.4 bits (150), Expect = 4e-09
Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569
AP +KD G+ L C + G P+P I W G+ + +R + + L
Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 30591
Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628
+ ED G YTC+A N +G+V S S+ LL P P P+ +
Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 30638
Query: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
+ GS + + V G P P + W H +Q SE+ E L ++ V +
Sbjct: 30639 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 30694
Query: 689 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
G Y + N G V A+L V+ +P + P + A L S +IS
Sbjct: 30695 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 30743
Score = 62.0 bits (149), Expect = 5e-09
Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I +D G +TC VN +G S S L++Q + F +ET A VT
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1049
Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
+ E K ++S + + + Q G P A
Sbjct: 1050 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1081
Score = 62.0 bits (149), Expect = 5e-09
Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329
+++ + V + TI + H + ++ +NK G + + +
Sbjct: 16256 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 16315
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383
P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A
Sbjct: 16316 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 16374
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
S+ V L+ +Y+FRV AIN G S S+ T + P
Sbjct: 16375 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 16422
Score = 62.0 bits (149), Expect = 5e-09
Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y AKN +G A+ S V V D P P +L T+ + T+
Sbjct: 17978 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 18021
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
+ P D G IT +++RK Q+ +
Sbjct: 18022 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 18052
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340
+ L A E+ + + ENK+G ++ + + +D+P P A
Sbjct: 18053 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 18110
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
D + + L W YDGGS SY +E + W+ + + + T + V + +
Sbjct: 18111 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 18169
Query: 1399 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
Y+FRV+ N G S+ + E+ V E ++P ++++S
Sbjct: 18170 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 18208
Score = 61.6 bits (148), Expect = 7e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)
Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143
T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++
Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149
Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194
+SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA +
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209
Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238
+ E + R + + S ATV+ K P+ PPK + PP
Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269
Query: 1239 QI 1240
I
Sbjct: 270 SI 271
Score = 61.6 bits (148), Expect = 7e-09
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
II D ++T A N G ++ + L VE +E
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1551
Score = 61.6 bits (148), Expect = 7e-09
Identities = 48/217 (22%), Positives = 87/217 (40%), Gaps = 36/217 (16%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
E P+F+ P + + G+ + +G + W + + + SGG + + S
Sbjct: 4204 EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALES-S 4262
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L ++ V D G YTC+ +N +G + + L F K+
Sbjct: 4263 LELYLVKTSDSGTYTCKVSNVAGGVECSANL-----FVKE-------------------- 4297
Query: 151 TRPSIWGECPPKFATKL-GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
P F KL ++K+G + +CK+TG P ++TW + ++ S++ +
Sbjct: 4298 ---------PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRM 4348
Query: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
S VL + V +D G Y C N +G S+
Sbjct: 4349 SFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSS 4385
Score = 61.6 bits (148), Expect = 7e-09
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 1308 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364
+ ++ EN G + + +D DPP G P +I ++TL W Y GG +
Sbjct: 21331 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 21389
Query: 1365 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421
SY +E D N W + F V L D Y+FRV A N G S PS+ S+
Sbjct: 21390 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 21449
Query: 1422 TTVGEKPEEPKDEVEVSDDD 1441
T + E PK +V+V D
Sbjct: 21450 ITCRDDVEAPKIKVDVKFKD 21469
Score = 61.6 bits (148), Expect = 7e-09
Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
PAFK V G+ L + P + W + LK T + + ++I
Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 22207
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+ A ED G Y N AG+A + V V D P PP +
Sbjct: 22208 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 22249
Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
D T PP K G S+ + V T TW
Sbjct: 22250 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 22291
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331
S ++ TI A R + GC + + EN+ G S TV P
Sbjct: 22292 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 22338
Query: 1332 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387
P GTP + S+ + W DGGS V Y +E + + W +L T
Sbjct: 22339 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 22398
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
F L EY+FRV A N+ G +PS+ SE V P +P E +
Sbjct: 22399 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 22457
Query: 1448 DYRTVTINTEQKVSDFYDIEERLGSGKF 1475
++ T + K++ + ++ L G++
Sbjct: 22458 QWKKPTYDGGSKITGYIVEKKELPEGRW 22485
Score = 61.6 bits (148), Expect = 7e-09
Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P +K + VH E K+ + P TI W + L T + + S+S+
Sbjct: 22547 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 22603
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+ A+ D G Y AKN AG+ + V V D P PE P V+
Sbjct: 22604 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 22646
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275
S T +K PP II + +++ E+ L V Q ++C
Sbjct: 22647 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 22696
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330
KV G++ T + ++ NK G + + VV K
Sbjct: 22697 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 22736
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388
PD P P + + S+ + W + DGGS + Y +E D W
Sbjct: 22737 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 22795
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
V L+ +H+Y+FRV A N G SEPS S
Sbjct: 22796 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 22826
Score = 61.6 bits (148), Expect = 7e-09
Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
W+K K + K + G + + + G +G V
Sbjct: 24551 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 24601
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388
P P G P A I +++TL W +YDGGS + Y +E D + W + T
Sbjct: 24602 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 24661
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
F V L+ D Y+FRV A N G SEPS S T ++ + P ++
Sbjct: 24662 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 24710
Score = 61.6 bits (148), Expect = 7e-09
Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W +
Sbjct: 28145 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 28200
Query: 1381 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435
+ + R T F V L +EY+F V A N G S S L E P P V
Sbjct: 28201 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 28260
Query: 1436 EVSDDDEKEPEVDY 1449
+V+D + +++
Sbjct: 28261 KVTDTSKTTVSLEW 28274
Score = 61.2 bits (147), Expect = 9e-09
Identities = 27/81 (33%), Positives = 51/81 (62%), Gaps = 1/81 (1%)
Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
++ G +AR CK++G P +V WFK+++ + ES ++ Y + L I+DV +D
Sbjct: 3749 MLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRM-YFVNSEAILDITDVKVEDSGS 3807
Query: 1829 YTCKAVNSLGEATCTAELIVE 1849
Y+C+AVN +G +C+ E++++
Sbjct: 3808 YSCEAVNDVGSDSCSTEIVIK 3828
Score = 61.2 bits (147), Expect = 9e-09
Identities = 49/235 (20%), Positives = 90/235 (38%), Gaps = 48/235 (20%)
Query: 1098 PAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
P F +KL+ + + G L+C+++ P ++W N L + ++ S+ +
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQ 5482
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
+ ED G + C A+N AG CS +V V + P SS PP++ T
Sbjct: 5483 MNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVF--------------SSFPPIVET 5528
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
+A V L +++GT P W K ++
Sbjct: 5529 LKNA---------------------------------EVSLECELSGTPPFEVVWYKDKR 5555
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
Q++ S+ K+ + + + IL G Y +N++GS + + + P
Sbjct: 5556 QLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP 5610
Score = 61.2 bits (147), Expect = 9e-09
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC
Sbjct: 25002 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 25058
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
+ F V L + EY FR+ AIN G EP+ E+ E P+ E++
Sbjct: 25059 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 25110
Score = 61.2 bits (147), Expect = 9e-09
Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+HV G+ + L ++ PP W G L+ ++ + + + ++I + D G
Sbjct: 29748 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 29807
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223
Y KN G + +V + D P P+ E DAT +
Sbjct: 29808 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 29852
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
+P P+ A + +++ + + G + ++ +T + KF + + +E+
Sbjct: 29853 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 29902
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
+ + A + G Y +++++ ++ + + P PP T D+
Sbjct: 29903 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 29943
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396
+TL+WY DGGS V Y +E W NK + RST L
Sbjct: 29944 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 29998
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432
EY+ RV AIN G+ +PS+ S+ + KP+ P+
Sbjct: 29999 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 30040
Score = 60.8 bits (146), Expect = 1e-08
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3338 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3396
Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
D L I++ +D+ YT A N++G+ + TA L +E E E E+E
Sbjct: 3397 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447
Score = 60.5 bits (145), Expect = 2e-08
Identities = 60/238 (25%), Positives = 90/238 (37%), Gaps = 41/238 (17%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F Q L V V+EG+ + L C V P I W G+ +K + S + +
Sbjct: 8346 PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLEL 8405
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
D G Y C A N AG S+ TK
Sbjct: 8406 RDVAKADSGDYVCKASNVAG---------------SDTTK-------------------- 8430
Query: 1218 SDATVKKKPA--PKTPPKAAMPPQIIQFPEDQKVRAGE--SVELFGKVTGTQPITCTWMK 1273
S T+K KPA P T KAA+ ++ E Q +R E + KV G W K
Sbjct: 8431 SKVTIKDKPAVAPATK-KAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK 8489
Query: 1274 FR-KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
+ +Q+ + + + + +KL I + G Y + N+ G ++ VNL V ++
Sbjct: 8490 GKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 8547
Score = 60.5 bits (145), Expect = 2e-08
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T
Sbjct: 19589 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 19647
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
F V L+ D +Y+FRV A+N G S+PS
Sbjct: 19648 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 19676
Score = 60.5 bits (145), Expect = 2e-08
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 1325 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
+ ++P PP D SS L+W +DGGS + Y +E+ + W E
Sbjct: 28540 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 28598
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
+ +F V+ L+ EY+FRV+A N G SEP + + E EP
Sbjct: 28599 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 28645
Score = 60.5 bits (145), Expect = 2e-08
Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P + + K + + C++ G P P++ W+ G + Q ++ D +H L
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 30591
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
++ D G Y+C A+N G++ S L ++ A + P + K + G L
Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 30648
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589
G PVP +TW + +Q + + T E H+ ++ + H G Y N
Sbjct: 30649 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 30708
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G V V + +K P KPT PI ++ L + + +S
Sbjct: 30709 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 30745
Query: 650 PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702
PP + W+ N E +E ++ + C E+ G Y A N+ G
Sbjct: 30746 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 30805
Query: 703 ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
+ +V+ ++ P + +P KP ++TA SC +A P
Sbjct: 30806 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 30847
Score = 60.5 bits (145), Expect = 2e-08
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G
Sbjct: 32847 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 32905
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
F L IH D G YTC N +G+ + +LT++
Sbjct: 32906 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 32942
Score = 60.1 bits (144), Expect = 2e-08
Identities = 72/302 (23%), Positives = 123/302 (40%), Gaps = 31/302 (10%)
Query: 313 QPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER- 371
+P+P E+++++ K P TP+ ++ +T+ + E +AP P G +
Sbjct: 11020 EPKPKPEAEVKTIKPPPVEPEPTPI----AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKG 11075
Query: 372 --KRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQ 429
K+ P A +PG G + +A P Q + KF + + + E++
Sbjct: 11076 VPKKTPSPIEAERRKLRPGSGGEKPPDEA-----PFTYQLKAVPLKFVKEIKDIILTESE 11130
Query: 430 TVK----FRCEVSGIPKPEVA-WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V F C VS P + W +G+ +R + D L ++ + D+G
Sbjct: 11131 FVGSSAIFECLVS--PSTAITTWMKDGSNIR-ESPKHRFIADGKDRKLHIIDVQLSDAGE 11187
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+C + + + L VE L V V ++ ++ V++GQ L C +
Sbjct: 11188 YTCVLRLGNKEKTSTAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCELNKER--D 11241
Query: 545 ITWLLNGQPIQYARSTCEAGVA----ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
+ W +G+ + GV L I DA D GTYT ENA + CS+ V V
Sbjct: 11242 VVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKV 11300
Query: 601 HE 602
E
Sbjct: 11301 VE 11302
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384
V KP PP G P D SS++++W YDGGS + Y +EI W+ + A
Sbjct: 21753 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 21811
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
++TS+ + L + EYK R+ A+N G EP+
Sbjct: 21812 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 21843
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
W K K + MKV + G Y + EN G + + V
Sbjct: 25633 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 25681
Query: 1331 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386
DP P G P ++I S++L W YDGG+ + Y +E + + W + +
Sbjct: 25682 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 25741
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D
Sbjct: 25742 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 25797
Score = 59.7 bits (143), Expect = 3e-08
Identities = 52/241 (21%), Positives = 87/241 (36%), Gaps = 54/241 (22%)
Query: 1084 TTDNEKRSESQGTA------PAFKQKLQDVHVA-EGKKLLLQCQVSSDPPATIIWTLNGK 1136
T NE S S P+F +K+ ++ G+ L C++ P + W N K
Sbjct: 3717 TASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNK 3776
Query: 1137 TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT 1196
L + + + S + I ED G Y C A ND G CS ++ + +
Sbjct: 3777 ELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE------- 3829
Query: 1197 KAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1256
PP I+ E + G +
Sbjct: 3830 ----------------------------------------PPSFIKTLEPADIVRGTNAL 3849
Query: 1257 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKL 1316
L +V+GT P +W K +KQI+ S+ ++ + ++ L I + G Y +V N++
Sbjct: 3850 LQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEV 3909
Query: 1317 G 1317
G
Sbjct: 3910 G 3910
Score = 59.3 bits (142), Expect = 3e-08
Identities = 73/351 (20%), Positives = 128/351 (36%), Gaps = 64/351 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+F +K++ G Q + P T+ W + + I ++ E ++ S+ +
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYL 4545
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA----------------PASENTK---A 1198
+ G Y C AKNDAG CS ++V + PA+ K
Sbjct: 4546 SGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGT 4605
Query: 1199 PEMKSRRPKSSLPPVLGTESDATV------------KKKPAP-----------KTPPKAA 1235
E+ ++ K LG++ +V +KK + ++ KA
Sbjct: 4606 KEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKAR 4665
Query: 1236 M-------PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
+ PP + + G ++L V G+ PI+ W K ++I SE K
Sbjct: 4666 INVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSF 4725
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP---DPPAGTPCASDIR- 1344
+N + L I G YT NK G Q +LTV + P + P + R
Sbjct: 4726 HDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRV 4785
Query: 1345 --------SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST 1387
++ +T+ W+ + + S + +W T EL ++T
Sbjct: 4786 QLKALVGGTAPMTIKWFKDNKELHSGA---ARSVWKDDTSTSLELFAAKAT 4833
Score = 59.3 bits (142), Expect = 3e-08
Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
PYF K + ++V G +A C++ G P+ V W+K D +R + +++ + + +L+
Sbjct: 7961 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHF-RNNVATLV 8019
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ V +D +Y CKA NS+GE + + L V+
Sbjct: 8020 FNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051
Score = 58.9 bits (141), Expect = 4e-08
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 2/128 (1%)
Query: 1721 SSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 1780
++ G +S N LE+ E + +E E + P + I LEV G A+F C+
Sbjct: 3420 NAVGQVSSTANLS-LEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCE 3478
Query: 1781 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
I+ P+ WFK + I ES I + + SL I D +YTCKA N G
Sbjct: 3479 IQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSV 3537
Query: 1841 TCTAELIV 1848
+CTA L V
Sbjct: 3538 SCTATLTV 3545
Score = 58.9 bits (141), Expect = 4e-08
Identities = 51/237 (21%), Positives = 86/237 (36%), Gaps = 44/237 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F +L+ + A G + LQCQV+ P T+ W L+ T ++ ++
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVF 6138
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
K D G Y C A+N +GT
Sbjct: 6139 NKVNINDSGEYTCKAENS--------------------------------------IGTA 6160
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
S TV + + +PP + +D + G V L ++ G+ PI W +
Sbjct: 6161 SSKTVFR------IQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVL 6214
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
+++ E+++ +N + L IL H G Y+ N LG+ + LT + P
Sbjct: 6215 LRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSP 6271
Score = 58.9 bits (141), Expect = 4e-08
Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 4/157 (2%)
Query: 1693 KWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEE 1752
KW K G + + + ++ + +SG K +P S E + V + A +
Sbjct: 7618 KWFKDGKELTSDNKYK-ISFFNKVSGLKIINVAP-SDSGVYSFEVQNPVGKDSCTASLQV 7675
Query: 1753 KPH-VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
V P F++ +++ + GS+ +CK+ G P V WF + I R +Q D
Sbjct: 7676 SDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTL-TD 7734
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
C+L ++ + D YTC A N G C+A L V
Sbjct: 7735 NTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 7771
Score = 58.9 bits (141), Expect = 4e-08
Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)
Query: 1131 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189
W T+K TK + EGSL +++ A+N GQ++ + ++D
Sbjct: 14130 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 14173
Query: 1190 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249
+ +++T + PP D T + PPK I ++ ++K
Sbjct: 14174 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 14224
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
R G W+K K + +V + G+++ + G
Sbjct: 14225 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 14265
Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
+G + ++ P P P +D + ++W +GGS + Y
Sbjct: 14266 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 14319
Query: 1367 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
+E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE
Sbjct: 14320 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 14379
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456
+ +P ++E D E E V +R V + T
Sbjct: 14380 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 14417
Score = 58.9 bits (141), Expect = 4e-08
Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G+ L+ V P TI W K ++ + + + ++ A+ D G Y
Sbjct: 23637 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 23696
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
A N AG V V D P P V G S+ K
Sbjct: 23697 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 23739
Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
+PP I + +++ E+ L V ++ +T
Sbjct: 23740 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 23775
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343
N K+T L E+ + ++ NK G + + V+ K P PP ++I
Sbjct: 23776 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 23830
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401
S+T+ W DGGS + Y +E D + W + R T V L DHEY+
Sbjct: 23831 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 23890
Query: 1402 FRVRAINVYGTSEPS 1416
FRV A N G EPS
Sbjct: 23891 FRVSAENAAGVGEPS 23905
Score = 58.5 bits (140), Expect = 6e-08
Identities = 60/273 (21%), Positives = 100/273 (36%), Gaps = 48/273 (17%)
Query: 1061 SASKEELKKDVKNDVN--CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQ 1118
+AS E ++ D+ + N C+ ++ + + + P+F K V G + L+
Sbjct: 4167 TASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLK 4226
Query: 1119 CQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1178
P TI W K L + +++E S+ + D G Y C N AG
Sbjct: 4227 STFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGG 4286
Query: 1179 AECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPP 1238
ECS + V + AT +K P
Sbjct: 4287 VECSANLFV-----------------------------KEPATFVEKLEP---------- 4307
Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298
Q ++ G++ +L KVTGT PI TW ++I+ES ++ E+ + L +
Sbjct: 4308 -------SQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLT 4360
Query: 1299 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
E G Y +N+ GS + V + P
Sbjct: 4361 DVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP 4393
Score = 58.5 bits (140), Expect = 6e-08
Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V E + +F C ++ + V W +G + + ++ D H L + ++ D G
Sbjct: 11497 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 11553
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+ + +G+ + + RL V + F S L+D V EG+ C + +
Sbjct: 11554 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 11603
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
+ W N + +R+ + + H + + E L +S V E
Sbjct: 11604 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 11651
Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
S+ + + L P F L D ++ ++T+ +VS + P V W +G EI
Sbjct: 11652 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 11702
Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
S + + G + L I++ +D G Y C+ G +T+A +TV+ + +
Sbjct: 11703 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 11753
Query: 725 SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781
KP V +G++ ++ P VH W G+ L + E++++ L+L
Sbjct: 11754 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 11809
Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827
Q G+ N + +V + S + + REP +
Sbjct: 11810 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 11869
Query: 828 CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884
L G + G DR+ ++ G + ++ ED + + +HT
Sbjct: 11870 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 11922
Query: 885 --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938
E IR + + L +D+ K+ V T LS D+++ + + N QR ++V
Sbjct: 11923 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 11974
Query: 939 S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997
S ++E K HS + F+ L+ TS+ V + + KL G
Sbjct: 11975 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 12017
Query: 998 S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055
+ + + VE + + + S PV K + +KP NA
Sbjct: 12018 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 12064
Query: 1056 DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112
+K+ K+ LKK +K+D+ GT + + + + L V V E
Sbjct: 12065 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 12121
Query: 1113 KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ + ++S D W L G+ L T + +EG + S+ + + G
Sbjct: 12122 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 12174
Score = 58.5 bits (140), Expect = 6e-08
Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)
Query: 1090 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147
R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + +
Sbjct: 24699 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 24758
Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207
++ ++ + D G Y N G V V D P P
Sbjct: 24759 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 24805
Query: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267
V G ++ P A + II+ E ++
Sbjct: 24806 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 24847
Query: 1268 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+W + ++Q + K+T L E+ + ++ NK G + + V
Sbjct: 24848 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 24893
Query: 1328 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381
KP P TP S I S+ ++W DGG+ ++ Y +E D W +
Sbjct: 24894 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 24953
Query: 1382 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
T V L H Y+FRV A N G EPS+ S
Sbjct: 24954 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 24991
Score = 58.5 bits (140), Expect = 6e-08
Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T +
Sbjct: 30531 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 30589
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + +ED G YTC ATN G + + +L ++ + G P+ K G
Sbjct: 30590 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 30640
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
G R GRP P +TW G LQ S +++
Sbjct: 30641 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 30678
Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
L + V + G Y + N G ++ IQ D V E N
Sbjct: 30679 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 30738
Query: 269 SDV 271
S V
Sbjct: 30739 SAV 30741
Score = 58.5 bits (140), Expect = 6e-08
Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386
+KP P G P + + S ++W + DGG+ +++Y +E + W + T R
Sbjct: 30823 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 30881
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE
Sbjct: 30882 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 30932
Score = 58.5 bits (140), Expect = 6e-08
Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156
P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++
Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 31854
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214
I LPED G Y+ A N AG C + V+ + K+ E R + + L
Sbjct: 31855 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 31914
Query: 1215 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250
GTES +A V KPA T K +I + E++K+R
Sbjct: 31915 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 31969
Score = 58.2 bits (139), Expect = 8e-08
Identities = 42/230 (18%), Positives = 82/230 (35%), Gaps = 47/230 (20%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+F ++L++ G +L+C+V+ P ++ W + + + ++C++ +
Sbjct: 5800 PSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL 5859
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
D G Y CVA N AG EC +TV + P+
Sbjct: 5860 NSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPS------------------------- 5894
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
++ PE +V G++V + GT P W + ++
Sbjct: 5895 ----------------------FVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARE 5932
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+ + + + + ++L + G YT +V N G L V
Sbjct: 5933 LVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 5982
Score = 58.2 bits (139), Expect = 8e-08
Identities = 55/284 (19%), Positives = 97/284 (34%), Gaps = 65/284 (22%)
Query: 1057 ENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1116
+N+ + L + C + +D + + P+F ++ + + V GK +
Sbjct: 5852 DNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVT 5911
Query: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE---------DRGL 1167
+ PP + W + L +G C++ E + E G
Sbjct: 5912 FTSVIRGTPPFKVNWFRGARELV---------KGDRCNIYFEDTVAELELFNIDISQSGE 5962
Query: 1168 YKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPA 1227
Y CV N+AGQA C+ ++ V +
Sbjct: 5963 YTCVVSNNAGQASCTTRLFVKE-------------------------------------- 5984
Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
P ++ D V G+S+ L TGT PI+ TW K I SE +
Sbjct: 5985 ---------PAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIV 6035
Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+E L IL + + G Y+ +EN+ G ++ ++ P
Sbjct: 6036 TTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPP 6079
Score = 58.2 bits (139), Expect = 8e-08
Identities = 49/237 (20%), Positives = 84/237 (35%), Gaps = 44/237 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F + L+ V G+ LQC+V P I W L++ + + ++ S+ I
Sbjct: 7020 PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 7079
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
K D G Y C A N G S + + K+R+
Sbjct: 7080 NKVDHSDVGEYSCKADNSVGAVASSAVLVI--------------KARK------------ 7113
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+PP + +D G V ++ G++P+ +W K
Sbjct: 7114 ------------------LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVL 7155
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
+++ +++ N + L IL Q H G Y N LG+ + L + + PP
Sbjct: 7156 LKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPP 7212
Score = 57.8 bits (138), Expect = 1e-07
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1816
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1082 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1141
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+IS DD +YT N GE + +A L+ E
Sbjct: 1142 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1174
Score = 57.8 bits (138), Expect = 1e-07
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 50/233 (21%)
Query: 1102 QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT---KFIILSQEGSLCSVSIE 1158
+K + V G+ L+C+V+ P ++ W +GK L ++ KF ++ SL +S+E
Sbjct: 5708 EKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVE 5767
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
+ +D G Y +N+ G++ C+ V V D
Sbjct: 5768 R---QDAGTYTFQVQNNVGKSSCTAVVDVSD----------------------------- 5795
Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
A+PP + ++ G S L KV G+ PI+ W + +I
Sbjct: 5796 ---------------RAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKI 5840
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ S+N L + + G YT + N GS + + LTV + P
Sbjct: 5841 VSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPP 5893
Score = 57.8 bits (138), Expect = 1e-07
Identities = 51/227 (22%), Positives = 84/227 (37%), Gaps = 41/227 (18%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+ + E P+F P ++ + G + F +RG P +V W + + + G C I
Sbjct: 6828 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGE----SCNIS 6883
Query: 87 ---GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
L + V + G Y+C TN +G+ T L F K+
Sbjct: 6884 LEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHL-----FVKE------------- 6925
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
P F +L V+ G TG P V+W+K +
Sbjct: 6926 ----------------PATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQ 6969
Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
S R S++ +LEI +D Y+CL+ N +G+ A +S+
Sbjct: 6970 SERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSV 7016
Score = 57.8 bits (138), Expect = 1e-07
Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
+ ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V
Sbjct: 24187 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 24246
Query: 1366 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
Y +E+ + W +A + + V L EY+FRV+A N G S+P
Sbjct: 24247 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 24296
Score = 57.8 bits (138), Expect = 1e-07
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 1739 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 31773 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 31832
Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 31833 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 31892
Query: 1856 GEGEEEEE 1863
E + +EE
Sbjct: 31893 QEFKSKEE 31900
Score = 57.4 bits (137), Expect = 1e-07
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1816
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3296
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Score = 57.4 bits (137), Expect = 1e-07
Identities = 50/237 (21%), Positives = 87/237 (36%), Gaps = 47/237 (19%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F +K+ D+ G+ + LQ V P ++ W + ++ I +S + + I
Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLII 3983
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
G Y C+A+N+AG Q +V + E
Sbjct: 3984 PDVQISFGGKYTCLAENEAGS-----QTSVGELIVKE----------------------- 4015
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
P +II+ E +V AG+ L V GT + W K +
Sbjct: 4016 -------------------PAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRP 4056
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
+ S+ ++ N ++L +A G YT + N++GS + TV+D+ P
Sbjct: 4057 LVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAP 4113
Score = 57.4 bits (137), Expect = 1e-07
Identities = 28/93 (30%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
Query: 1758 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
P F K + +V +G + + +CKI G P+ +V WF++D + ES + + + + L
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF-INSVALL 6422
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
I++ +D Y C+A N +G+A+C+ L V+
Sbjct: 6423 TINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455
Score = 57.4 bits (137), Expect = 1e-07
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F K +E ++G+ +C+++G P V W+KD + +R + ++I E+ S+
Sbjct: 7399 PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI-MSENFLTSIH 7457
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
I +V D +Y CKA N +G TC + ++
Sbjct: 7458 ILNVDAADIGEYQCKATNDVGSDTCVGSIALK 7489
Score = 57.4 bits (137), Expect = 1e-07
Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
V KP PP D +S+TL+W YDGGS + Y +EI + + W+ +
Sbjct: 23917 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 23975
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1442
R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E
Sbjct: 23976 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 24029
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Query: 1302 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358
QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D
Sbjct: 25263 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 25322
Query: 1359 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q
Sbjct: 25323 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 25381
Score = 57.0 bits (136), Expect = 2e-07
Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 8/160 (5%)
Query: 1693 KWQKTGNAVRAIGRLSSMAMISGLSG-RKSSTGSPTSPLNAEKLESEEDVSQ--AFLEAV 1749
KW K G + R SM+ + ++ R S S K+E++ S A+L +
Sbjct: 5173 KWLKDGKQI-VPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVL 5231
Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809
+ P P F+K + ++ V GS+ +CK+ G WFKD + I S +++
Sbjct: 5232 DQNIP---PSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCH 5288
Query: 1810 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
E + SL ++++ +D A YTCK N G+ C+ L V+
Sbjct: 5289 E-RSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327
Score = 57.0 bits (136), Expect = 2e-07
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
PYF + LE G + C++ G P+ V W+K D +R + ++ Y + +L+
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYR-TYFTNNVATLV 6137
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEAT 1841
+ V +D +YTCKA NS+G A+
Sbjct: 6138 FNKVNINDSGEYTCKAENSIGTAS 6161
Score = 57.0 bits (136), Expect = 2e-07
Identities = 55/269 (20%), Positives = 96/269 (35%), Gaps = 62/269 (23%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F ++L D V G ++L+ + PP ++ W + + ++ ++ + I +
Sbjct: 6929 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 6988
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
+ ED Y C+ +N+AGQ C V+V +
Sbjct: 6989 STIEDYAQYSCLIENEAGQDICEALVSVLE------------------------------ 7018
Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
PP I+ E + GE L KV GT I +W K +++
Sbjct: 7019 -----------------PPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLR 7061
Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----- 1334
+ K++ N + L I G Y+ +N +G+ + L + + PP
Sbjct: 7062 SAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARK 7121
Query: 1335 -------AGTPCASDIR---SSSLTLSWY 1353
G P A + R S L +SWY
Sbjct: 7122 LKDVHETLGFPVAFECRINGSEPLQVSWY 7150
Score = 57.0 bits (136), Expect = 2e-07
Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
Query: 1758 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
P F K + +V + R++CKI G P+ +V+W+KD+ I+ES F++ + D L
Sbjct: 7305 PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF-VDSVAVL 7363
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ ++ +D YTC+A N+ G A+ + L V+
Sbjct: 7364 EMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396
Score = 56.6 bits (135), Expect = 2e-07
Identities = 50/225 (22%), Positives = 79/225 (35%), Gaps = 32/225 (14%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+ + E I P + + G E V G PE W ++G+ +++ + + I
Sbjct: 6639 LTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITF-IN 6697
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
SL I D+G Y+ E N G TV + V DR
Sbjct: 6698 KVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVS-----------------DRI-- 6738
Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
PP F KL V G C+++G V W + + +
Sbjct: 6739 ------------VPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPK 6786
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
S + L + + D G+YTC+ N +G SA L++Q
Sbjct: 6787 CQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 6831
Score = 56.6 bits (135), Expect = 2e-07
Identities = 53/224 (23%), Positives = 87/224 (38%), Gaps = 41/224 (18%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
E F+ + ++ G+ E G P V+W ++ I+ R C I T
Sbjct: 6925 EPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSER----CSITMTEK 6980
Query: 91 LVIHAVHE---EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
I + E ED +Y+C N +G + + + +VS
Sbjct: 6981 STILEILESTIEDYAQYSCLIENEAG---------------QDICEALVS---------- 7015
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
+E PP F L V G+ CK+ G P+ +++W K + L+ +
Sbjct: 7016 VLE---------PPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAY 7066
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
+ KN + L I+ V+ DVG Y+C N G + SA L I+
Sbjct: 7067 KMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIK 7110
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y
Sbjct: 16536 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 16593
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
+AKN+AG+ + + V V D P T P + S
Sbjct: 16594 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 16633
Query: 1229 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
++ F PED G PIT ++ +++ V
Sbjct: 16634 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 16667
Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341
+ T+ Q + + EN +G + +A V + P+ P
Sbjct: 16668 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 16726
Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399
++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L
Sbjct: 16727 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 16786
Query: 1400 YKFRVRAINVYGTSEPS 1416
Y++RV A+N+ G +PS
Sbjct: 16787 YEYRVSAVNIVGQGKPS 16803
Score = 56.6 bits (135), Expect = 2e-07
Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + ++ V P T+ W + LK T+ + + ++I + + D G Y
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 21139
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A+N G+ + V D P PP + D
Sbjct: 21140 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 21170
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
+ + F D G V Q + TW++ + + +
Sbjct: 21171 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 21219
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
++LT Q + + +N+ G + +V P PP GTP + +
Sbjct: 21220 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 21273
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV
Sbjct: 21274 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 21333
Query: 1405 RAINVYGTSEPSQESE 1420
A N+ G S+PS+ SE
Sbjct: 21334 IAENMAGKSKPSKPSE 21349
Score = 56.6 bits (135), Expect = 2e-07
Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)
Query: 1057 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115
E L ++ E + KND A ++ K + + TA Q + G
Sbjct: 28606 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 28665
Query: 1116 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
+ +S P + W L LK T + ++ +++++ ++ D G Y +N
Sbjct: 28666 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 28725
Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
AG S V V P P + V +++ V PK
Sbjct: 28726 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 28772
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
+ I++ E T W ++ ++ K+
Sbjct: 28773 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 28802
Query: 1296 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351
T L E+ + + EN+ G S+ + + + P P P + + ++++++
Sbjct: 28803 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 28860
Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N
Sbjct: 28861 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 28920
Query: 1410 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
G S+ S+ S + + P + EV+D
Sbjct: 28921 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 28949
Score = 56.2 bits (134), Expect = 3e-07
Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F++ + ++GS C+I G P EVVW KD + +R S+ F+I + + SL
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKIT-SKHFDTSLH 6516
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1846
I ++ D +Y CKA N +G TC+ +
Sbjct: 6517 ILNLEASDVGEYHCKATNEVGSDTCSCSV 6545
Score = 56.2 bits (134), Expect = 3e-07
Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Query: 1740 DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
+VS + V E+K + P FS+ +RD++ G FDC I G V W+KD + ++
Sbjct: 8041 EVSASTFLTVQEQK--LPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLK 8098
Query: 1800 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+S + Q + D +L I +Y+C A N +G A+ +A LI+
Sbjct: 8099 DSPNVQTSF-LDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 8146
Score = 56.2 bits (134), Expect = 3e-07
Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387
P P P +D S +L+W YDGG + Y +E ++ W + T R T
Sbjct: 20672 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 20731
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+
Sbjct: 20732 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 20782
Query: 1448 DYRTVTINTEQKVSDFYDIEER 1469
RT+ + + F I+ R
Sbjct: 20783 -RRTLVVRAGLSIRIFVPIKGR 20803
Score = 55.8 bits (133), Expect = 4e-07
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 1726 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1783
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1807 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1866
Query: 1784 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1867 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1924
Query: 1844 AELIVETMEE 1853
+L ++ E+
Sbjct: 1925 VKLEIQQRED 1934
Score = 55.8 bits (133), Expect = 4e-07
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 1306 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
GC + ++ EN+ G + V + P PP DI S+++L+W +DG
Sbjct: 20934 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 20992
Query: 1360 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
GS + Y IE + W + T + V++L EY F+V A+N G S P +ES
Sbjct: 20993 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 21051
Query: 1420 ELTTVGEKPEEPK 1432
V E+ P+
Sbjct: 21052 RPVIVKEQTMLPE 21064
Score = 55.5 bits (132), Expect = 5e-07
Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
AP F Q LQ V V EG + +S P + W +G+ + T+ + +S
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
++I + G Y A N +GQA + ++ V A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
PP +Q + VR G V L +VTG + +
Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
+IQ S ++ + L I A E G Y++ N +G + L V + + P
Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Query: 1335 A 1335
A
Sbjct: 201 A 201
Score = 55.5 bits (132), Expect = 5e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F + L G AA+F C + G P E +W KD ++ S +++I D + L
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRIS-DAENKHILE 3609
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+S++ D Y+CKA N G C AELI+
Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADICQAELII 3640
Score = 55.5 bits (132), Expect = 5e-07
Identities = 67/319 (21%), Positives = 123/319 (38%), Gaps = 53/319 (16%)
Query: 1082 AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT 1141
+ + D R Q P+F +KL + G + ++C+VS P + W +GK + T+
Sbjct: 5221 SSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTS 5280
Query: 1142 -KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
K+ ++ E S+ S+ + ED Y C N AG CS +TV + P S K P
Sbjct: 5281 AKYRLVCHERSV-SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE-PPSFLVK-PG 5337
Query: 1201 MKSRRPKSSL---------PP---------------------VLGTESDATVKKKPAPKT 1230
+ P S++ PP + G+ S + A KT
Sbjct: 5338 RQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKT 5397
Query: 1231 PPKAAM------------------PPQIIQFPEDQK-VRAGESVELFGKVTGTQPITCTW 1271
PP+ ++ E K V+AG+S L K+ G+ I W
Sbjct: 5398 GQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVW 5457
Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ ++ S+ ++ ++ + + + E G + +N GS + V + P
Sbjct: 5458 FRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 5517
Query: 1332 DPPAGTPCASDIRSSSLTL 1350
+ P ++++ ++L
Sbjct: 5518 VFSSFPPIVETLKNAEVSL 5536
Score = 55.5 bits (132), Expect = 5e-07
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
+P P+F ++V+ G +A F+C + G + W KD++ IR ++ I G
Sbjct: 6266 EPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITC--VG 6323
Query: 1813 NC-SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
N L I V D +YTC+A N +G+ C+A+L V+
Sbjct: 6324 NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVK 6361
Score = 55.5 bits (132), Expect = 5e-07
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1812
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 30924 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 30983
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
LII+ V DD Y +A N G + TA L VE
Sbjct: 30984 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 31020
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 33192
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
I + D KYT KA N G+ + TA L+V + E
Sbjct: 33193 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 33228
Score = 55.1 bits (131), Expect = 6e-07
Identities = 41/159 (25%), Positives = 71/159 (44%), Gaps = 5/159 (3%)
Query: 1691 RRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVA 1750
R W GN + AI + ++ I GL+ + S G+ E+ D A
Sbjct: 4892 RVSWYLDGNEITAIQK-HGISFIDGLATFQIS-GARVENSGTYVCEARNDAGTA--SCSI 4947
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
E K P F + ++ +EVV+ S +C++ G P EV W K+++ IR S+ + + D
Sbjct: 4948 ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLT-DR 5006
Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+L I+ D +Y C N G +C+ + ++
Sbjct: 5007 VSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK 5045
Score = 55.1 bits (131), Expect = 6e-07
Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 1/85 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P FS +E ++ + +C++ G P EVVW+KD + +R S+ ++I ++ + S+
Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKI-ASKNFHTSIH 5575
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATC 1842
I +V D +Y CKA N +G TC
Sbjct: 5576 ILNVDTSDIGEYHCKAQNEVGSDTC 5600
Score = 55.1 bits (131), Expect = 6e-07
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388
P PP P +D SS L W DGGS V Y +E + + W++ R T
Sbjct: 16422 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 16479
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D
Sbjct: 16480 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 16532
Score = 55.1 bits (131), Expect = 6e-07
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386
KP P P D + L W DGGS + Y +E W + R
Sbjct: 17802 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 17861
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
+F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D
Sbjct: 17862 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 17916
Score = 55.1 bits (131), Expect = 6e-07
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268
TES + K K P PP++ + +++ E G +TG + +
Sbjct: 18382 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 18439
Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
W+ K MKV+N +H + + EN++G + + V
Sbjct: 18440 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 18488
Query: 1329 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378
DP P G P D S+TL W YDGG+ + Y +E+ S ++ W
Sbjct: 18489 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 18548
Query: 1379 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
K A F V L + EY+FRV A N G P++ E E E P+ ++
Sbjct: 18549 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 18608
Query: 1436 EVS 1438
+ S
Sbjct: 18609 DAS 18611
Score = 55.1 bits (131), Expect = 6e-07
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399
D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L +
Sbjct: 29645 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 29704
Query: 1400 YKFRVRAINVYGTSEPSQESELTTV 1424
Y FR+RA N G SEP + TV
Sbjct: 29705 YLFRIRAQNEKGVSEPRETVTAVTV 29729
Score = 55.1 bits (131), Expect = 6e-07
Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567
AP F L++ V + L C V G P P + W G+ I +Y + G +
Sbjct: 30927 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 30986
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I +D Y A N G VS +A + V P+K P L+
Sbjct: 30987 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 31032
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP
Sbjct: 31033 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 31088
Query: 688 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734
+D G Y A N G + V V +P G + +S+ + AS
Sbjct: 31089 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 31148
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA 760
G S + + + WLR G+A
Sbjct: 31149 GGSKITNYIVEKCATTAERWLRVGQA 31174
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383
PDPP I +++ LSW DGGS V Y +E WD + + W++
Sbjct: 16012 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 16070
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431
F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P
Sbjct: 16071 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 16117
Score = 54.7 bits (130), Expect = 8e-07
Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101
+ G + K + G P P + W+++ + + + L C + T L + + DR
Sbjct: 26885 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 26940
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
G Y + N G+ T+ + + G P+ KT+ E +W
Sbjct: 26941 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 26992
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204
K+ +V++ + R + + +KGN + +P
Sbjct: 26993 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 27052
Query: 205 ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260
SV KN G+ + + + VV A +++S ++ D + +
Sbjct: 27053 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 27112
Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
+ K T D R++VT + + + C+ G P +P
Sbjct: 27113 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 27158
Query: 321 KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378
K D P + + T SSITL ++ + G V GEE +
Sbjct: 27159 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 27218
Query: 379 PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421
T + PG+ VS A + P+E P+
Sbjct: 27219 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 27278
Query: 422 -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478
S K + V+ G P P V W + + GS Y E+ S L +
Sbjct: 27279 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 27334
Query: 479 TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528
TR D+G Y T N G+ S T+ V ++L V V+ ++L D +I+G
Sbjct: 27335 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 27393
Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
++ + + TW + + + D + + LAEN
Sbjct: 27394 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 27444
Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637
+G E PV ++ API + D DG
Sbjct: 27445 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 27490
Query: 638 SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697
V V E W H G I ++ + Q Q L + + G
Sbjct: 27491 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 27547
Query: 698 WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
+ G + + ++ E P VT +G +V + G P P++ WL+D
Sbjct: 27548 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 27600
Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817
G L K++ + E+ TL +K + H G+Y ++L N V C V + +
Sbjct: 27601 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 27657
Query: 818 ALPRG 822
+ P+G
Sbjct: 27658 SKPKG 27662
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)
Query: 1308 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
+ + EN G S T+ P P GTP D+ ++TL W DGGS +
Sbjct: 27829 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 27888
Query: 1366 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419
YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S
Sbjct: 27889 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 27944
Query: 1420 ELTTVGEKPEEP 1431
+ ++ P
Sbjct: 27945 GIIMTRDENVPP 27956
Score = 54.3 bits (129), Expect = 1e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 1746 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1547 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1603
Query: 1806 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1604 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1659
Score = 54.3 bits (129), Expect = 1e-06
Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%)
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
G+ + +V K + R+ + G R KF S + Q VKE +T F CE+S K V W
Sbjct: 11552 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 11606
Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
F + ++ + + +H L + + D +L
Sbjct: 11607 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 11656
Query: 508 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565
V+E P F+ L D +E + L+C V VP + W +G+ I S G+
Sbjct: 11657 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 11714
Query: 566 AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
L I+ A +D G Y C G A VTV + + KP
Sbjct: 11715 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 11756
Query: 625 FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684
L ++V G +++S P W G + S D + G +H L +
Sbjct: 11757 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 11811
Query: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744
TG + +A N+ ++ A L V+E FI+ V C +
Sbjct: 11812 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 11863
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782
+ +P T WL+ + + D FE++++ ++V+K
Sbjct: 11864 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 11899
Score = 54.3 bits (129), Expect = 1e-06
Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158
F+ KL + G+ L + S P + W + L+ + I + +L I
Sbjct: 16824 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 16879
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
KA D G Y V +N G + CQV V D P PPV
Sbjct: 16880 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 16921
Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
D K P I +K G+ V + + + TC K K +
Sbjct: 16922 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 16977
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
+ +++ ++EN Y + S +A+ V D PD P T
Sbjct: 16978 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 17022
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395
D S ++W +DGG + +Y +E ++ +K W + T F V DLL
Sbjct: 17023 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 17077
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448
+Y+FRV A N G +PS S+ + +P V D VD
Sbjct: 17078 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 17130
Score = 54.3 bits (129), Expect = 1e-06
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QL PV++K L PP F V G+ + GRP
Sbjct: 22133 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 22175
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A
Sbjct: 22176 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 22229
Score = 54.3 bits (129), Expect = 1e-06
Identities = 26/77 (33%), Positives = 44/77 (57%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y
Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 23300
Query: 232 TCLVVNGSGKASMSAEL 248
V N G+ + S E+
Sbjct: 23301 GITVANVVGQKTASIEI 23317
Score = 54.3 bits (129), Expect = 1e-06
Identities = 25/72 (34%), Positives = 40/72 (55%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G+ + + GRP+P ++W+K PL+ + RV+V E VL I N+DD G Y
Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382
Query: 232 TCLVVNGSGKAS 243
T N +G A+
Sbjct: 24383 TVTATNSAGTAT 24394
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1814
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 31748
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 31749 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 53.9 bits (128), Expect = 1e-06
Identities = 51/230 (22%), Positives = 81/230 (35%), Gaps = 35/230 (15%)
Query: 22 SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLL 81
+R++ + L P+F + + +G+ E V G + W ++ Q I++ ++
Sbjct: 4664 ARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKF 4723
Query: 82 DCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG 141
F L I + D G YTC ATN +G Q + LTV+
Sbjct: 4724 SFHDNTAF-LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE---------------- 4766
Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
PP F K V + + G + W K N L
Sbjct: 4767 ------------------PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKEL 4808
Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
A SV + + LE+ D G Y C + N G A+ A L ++
Sbjct: 4809 HSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK 4858
Score = 53.9 bits (128), Expect = 1e-06
Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 23011
Query: 232 TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260
T + N SG + SA ++++ LD+ +
Sbjct: 23012 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 23069
Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311
V + +AT VTN K+D L+ A P + P A
Sbjct: 23070 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 23129
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363
PQPP + ++ + + T S I +Q + R L
Sbjct: 23130 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 23188
Query: 364 LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411
+ + GEE K + PR P + ++D+V +
Sbjct: 23189 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 23229
Query: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
P + S V+ Q +K +SG PKP + W +G P+ +Q I V +
Sbjct: 23230 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 23286
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCS 499
L + + D G Y T +N GQ + S
Sbjct: 23287 LSIKETHKDDGGQYGITVANVVGQKTAS 23314
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 32841 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 32900
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 32901 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 32950
Score = 53.5 bits (127), Expect = 2e-06
Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
PYF+K + +EV++ ++ G P E+ WFKD+ +R R ++ + +D SL
Sbjct: 4393 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYK-TFIQDHLVSLQ 4451
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1846
I D +Y C+ N +G + C+A +
Sbjct: 4452 ILKFVAADAGEYQCRVTNEVGSSICSARV 4480
Score = 53.5 bits (127), Expect = 2e-06
Identities = 53/245 (21%), Positives = 82/245 (33%), Gaps = 35/245 (14%)
Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
V S+ L P F+ ++ G + + + G V W ++ I +
Sbjct: 7483 VGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWIS 7542
Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
+L V + GKYTC+ N +G ++ L+V
Sbjct: 7543 YSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE------------------ 7584
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
P K + V G C + G P+ W K L
Sbjct: 7585 ----------------PATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTS 7628
Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263
+ +S N + L+I V D GVY+ V N GK S +A L + + SF R+
Sbjct: 7629 DNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSD-RTVPPSFTRK 7687
Query: 264 TKATN 268
K TN
Sbjct: 7688 LKETN 7692
Score = 53.5 bits (127), Expect = 2e-06
Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 6/110 (5%)
Query: 1746 LEAVAEEKPHVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 1804
LE AE + +P F+K I+++ V E +A F+C++ + D V W+K + ES+ +
Sbjct: 8821 LETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEV-SFDDAIVTWYKGPTELTESQKY 8879
Query: 1805 QIDYDEDGNCS-LIISDVCGDDDAKYTCKA-VNSLGEATCTAELIVETME 1852
++ DG C + I +V DD+ Y+ A + GEA TAEL + T E
Sbjct: 8880 --NFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKE 8927
Score = 53.1 bits (126), Expect = 2e-06
Identities = 25/93 (26%), Positives = 54/93 (58%), Gaps = 2/93 (2%)
Query: 1758 PYFSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
P F K + ++V+ G ++R +CKI G P+ VVWF+++ + S +++ + D +
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTF-IDSVAVI 5481
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
++++ +D + C+A N G +C+ ++IV+
Sbjct: 5482 QMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 5514
Score = 53.1 bits (126), Expect = 2e-06
Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R GRP P++TW + + +V + + L I +++D G
Sbjct: 24034 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 24091
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D
Sbjct: 24092 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 24143
Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328
AK KN +R + AN + + S K+E+ +
Sbjct: 24144 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 24202
Query: 329 ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375
P + P L +TS+S+ + R G V + P G E K
Sbjct: 24203 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 24261
Query: 376 PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423
GL S KA N + +P+ + + P + +
Sbjct: 24262 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 24321
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
++ + +K V G P+P ++W +G P+ +Q + V E A S L + + D G
Sbjct: 24322 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 24380
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
Y+ TA+N+ G + + ++ V V P F V D VI
Sbjct: 24381 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 24424
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G
Sbjct: 27968 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 28027
Query: 230 VYTCLVVNGSGKASMSAELSIQ 251
VYT N SG A ++ +Q
Sbjct: 28028 VYTVEAKNASGSAKAEIKVKVQ 28049
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 30592
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+++ +D+ YTC A N +GE +++L+++
Sbjct: 30593 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 30623
Score = 52.8 bits (125), Expect = 3e-06
Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
+G A + CK+ G P ++ WF +D+ I+ES ++ + E L ++DV +D +Y
Sbjct: 4313 KGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVE-STAVLRLTDVGIEDSGEYM 4371
Query: 1831 CKAVNSLGEATCTAELIVE 1849
C+A N G C++ +IV+
Sbjct: 4372 CEAQNEAGSDHCSSIVIVK 4390
Score = 52.8 bits (125), Expect = 3e-06
Identities = 37/113 (32%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
Query: 1737 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
S E S + VA ++P P F K I + V S+A F + G P + W KDDQ
Sbjct: 5030 SNEGGSCSCSTRVALKEP---PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQ 5086
Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ E + I + D +L I V +YTC+A N G C A L+V+
Sbjct: 5087 ILDEDDNVYISF-VDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138
Score = 52.8 bits (125), Expect = 3e-06
Identities = 50/235 (21%), Positives = 84/235 (35%), Gaps = 48/235 (20%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F K V +A G+ +C V+ P I W + + ++ ++ + ++++
Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTV 7271
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
K D G Y C A N AG+ CS Q+ V +
Sbjct: 7272 LKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE---------------------------- 7303
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRK 1276
PP+ I+ E + V+ E K+ G+ I W K
Sbjct: 7304 -------------------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDET 7344
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+IQES ++ ++ + L + E G YT N GS + +L V + P
Sbjct: 7345 EIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 7399
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
PT + + V G V + + ++G PPP W G++++ESE E
Sbjct: 29736 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 29795
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734
L I+E DTG YT E N G T V+ + +P T P I + S+T S
Sbjct: 29796 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 29855
Query: 735 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790
G + L + WL +++ + T F L + + + + G
Sbjct: 29856 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 29915
Query: 791 QYEILLKNRVGECSCQVSL 809
Y L++ V EC + +
Sbjct: 29916 SY---LQSEVIECRSSIRI 29931
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G
Sbjct: 1081 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1140
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
LVI +D G+YT N G + L E +
Sbjct: 1141 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1177
Score = 52.4 bits (124), Expect = 4e-06
Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F KT+ ++V G+ A C++ G E+ WFKD + IR S+ +++ + + L
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRL-FSQKSLVCLE 3889
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTA 1844
I D +Y C N +G+ C A
Sbjct: 3890 IFSFNSADVGEYECVVANEVGKCGCMA 3916
Score = 52.4 bits (124), Expect = 4e-06
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 1730 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1789
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 22121 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 22179
Query: 1790 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 22180 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 22237
Score = 52.4 bits (124), Expect = 4e-06
Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280
K P TP PP+ P + SV L K G +T +++ ++ +
Sbjct: 30315 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 30374
Query: 1281 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332
H K + + +T L E+ + ++ +N +G S + + VV DKP
Sbjct: 30375 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 30432
Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390
P S I S+TL W DGG + Y +E S + WK+ + F
Sbjct: 30433 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 30491
Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438
+ LL EY+FRV A N G S P S +++LT+ GE P K+ +V+
Sbjct: 30492 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 30543
Score = 52.4 bits (124), Expect = 4e-06
Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P F+ + ++ V+ C+V+G PKP V W+ +G + + E G ++
Sbjct: 30928 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 30987
Query: 474 LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
++ + T D T Y A+N G +S + +L+VE A + + P + + G+
Sbjct: 30988 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 31046
Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587
++ G P P ITW GQ + + V P +D G Y A+N
Sbjct: 31047 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 31105
Query: 588 ALG 590
G
Sbjct: 31106 RFG 31108
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G
Sbjct: 31578 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 31637
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
Y C VVN G+ S AEL ++G+ + R T
Sbjct: 31638 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 31672
Score = 52.0 bits (123), Expect = 5e-06
Identities = 54/233 (23%), Positives = 82/233 (35%), Gaps = 48/233 (20%)
Query: 1100 FKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158
F +KL+ + + G L C+V+ PP I W N + +K + +S S + +
Sbjct: 4301 FVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLT 4360
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
ED G Y C A+N+AG CS V V ++P
Sbjct: 4361 DVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPY-------------------------- 4394
Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
T + KP +V V L +V GT P TW K +
Sbjct: 4395 -FTKEFKPI--------------------EVLKEYDVMLLAEVAGTPPFEITWFKDNTIL 4433
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ K ++ L IL G Y V N++GS +T+ + P
Sbjct: 4434 RSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPP 4486
Score = 52.0 bits (123), Expect = 5e-06
Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
++ H+ G L L + P + W + T I ++ GS + I A ED
Sbjct: 17226 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 17283
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
G+Y +N AG S +V V D P P+ + +S K
Sbjct: 17284 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 17331
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+P G SV V + W ++ H
Sbjct: 17332 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 17369
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341
+E L +AA EN+ G + DP P G P
Sbjct: 17370 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 17417
Query: 1342 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
D+ + ++L W DGGS + Y +E + + W + T + V L
Sbjct: 17418 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 17477
Query: 1400 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
Y+FRV+A N+ G P + EK P E++V
Sbjct: 17478 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 17514
Score = 52.0 bits (123), Expect = 5e-06
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R
Sbjct: 27968 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 28026
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G YT EA N SG+ + +++ V+ + K +G + G++ +
Sbjct: 28027 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 28070
Score = 51.6 bits (122), Expect = 7e-06
Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%)
Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469
++A P F + QS V++ V+ + V+GIP P V ++ +G + + ++ ++
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158
Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
+ L + +A DSGTYS A+N+ G+ + + L V+
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 51.6 bits (122), Expect = 7e-06
Identities = 51/244 (20%), Positives = 83/244 (34%), Gaps = 55/244 (22%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSV 1155
AP F + L++V L C+++ P + W +GK + + ++ I EG+ S+
Sbjct: 4112 APFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGT-ASL 4170
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1215
I + D G + C A N G + S + V +
Sbjct: 4171 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE-------------------------- 4204
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
PP + P + V G +V L G+ P+T W K
Sbjct: 4205 ---------------------PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGN 4243
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL------TVVD 1329
K++ + S L + + G YT V N G + NL T V+
Sbjct: 4244 KELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVE 4303
Query: 1330 KPDP 1333
K +P
Sbjct: 4304 KLEP 4307
Score = 51.6 bits (122), Expect = 7e-06
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
+ ++V E +C + G P+ +V W KD + I SR+F + + E+ S I V
Sbjct: 5148 KSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSF-ENNVASFRIQSVMKQ 5206
Query: 1825 DDAKYTCKAVNSLGEATCTAELIV 1848
D +YT K N G ++C A L V
Sbjct: 5207 DSGQYTFKVENDFGSSSCDAYLRV 5230
Score = 51.6 bits (122), Expect = 7e-06
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327
W K K + + H KV G + + EN G +
Sbjct: 26716 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 26764
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
+D +PP +DI +S++LSW ++DGGS + Y +E D + W +
Sbjct: 26765 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 26823
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417
T F + L + +Y+FRV A N G+ S PS+
Sbjct: 26824 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 26856
Score = 51.2 bits (121), Expect = 9e-06
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
V P F + ++D+ + G++ +C++ G V WF+D I Q + E+ C+
Sbjct: 6739 VPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN-VCT 6797
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L +S + D YTC A N G C+A L V+
Sbjct: 6798 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 6831
Score = 51.2 bits (121), Expect = 9e-06
Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1816
P F K + D+ V G + IEG VVWFKD + +RES + I Y E+ +L
Sbjct: 7492 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSEN-IATL 7550
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
S V + KYTC+ N G C A L V
Sbjct: 7551 QFSRVEPANAGKYTCQIKNDAGMQECFATLSV 7582
Score = 51.2 bits (121), Expect = 9e-06
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385
+ P PP P +D S+++ L W +++GG + Y ++ W +
Sbjct: 15000 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 15057
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
+ V+++ +YK RV A+N G P E++ TV E E P E++VS
Sbjct: 15058 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 15109
Score = 50.8 bits (120), Expect = 1e-05
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
V P F++ +++ V G++ +CK+ G V WF + I +Q + D C+
Sbjct: 5798 VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTF-SDNVCT 5856
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L ++ + D YTC A N G C A L V+
Sbjct: 5857 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQ 5890
Score = 50.8 bits (120), Expect = 1e-05
Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)
Query: 1125 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183
PP T+ W + K L + + S ++I + D G Y +N G+ + S
Sbjct: 27299 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 27358
Query: 1184 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238
V V D PA+ + SR + L PP++ S + ++K+ A K
Sbjct: 27359 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 27410
Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298
TW + + ++ SE
Sbjct: 27411 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 27436
Query: 1299 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356
+ +L EN++G + V + PA S D +S+ LSW
Sbjct: 27437 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 27487
Query: 1357 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
+DGGS + Y +E +TW ++ V L +FRV A N G S+P
Sbjct: 27488 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 27547
Query: 1417 QESELTTVGEKPEEPKDEVEVSD 1439
+ TV E P EV++SD
Sbjct: 27548 TIGPI-TVKELIITP--EVDLSD 27567
Score = 50.8 bits (120), Expect = 1e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343
SE K+T L E+ + ++ EN G A L +P P G P +D
Sbjct: 28208 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 28265
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401
++++L W +DGG + Y IE+ + W ++ C T + V DL EYK
Sbjct: 28266 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 28325
Query: 1402 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
FRV AIN G + + + ++ P+ +++ +
Sbjct: 28326 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 28362
Score = 50.4 bits (119), Expect = 2e-05
Identities = 31/92 (33%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F K + DL + G + G V W K + IRE ++ + +G LI
Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGVAVLI 3982
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
I DV KYTC A N G T ELIV+
Sbjct: 3983 IPDVQISFGGKYTCLAENEAGSQTSVGELIVK 4014
Score = 50.4 bits (119), Expect = 2e-05
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
Query: 1742 SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 1801
S A L A + P P+F++ ++D+ G F+C+I G +V W+KD +++
Sbjct: 7103 SSAVLVIKARKLP---PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDD 7159
Query: 1802 RHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
+ Q + + +L I +Y C A N LG A+ +A+LI+ E
Sbjct: 7160 ANLQTSFVHN-VATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE 7209
Score = 50.1 bits (118), Expect = 2e-05
Identities = 55/281 (19%), Positives = 99/281 (35%), Gaps = 50/281 (17%)
Query: 1041 AKPAETLKPMGNAKPD--ENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAP 1098
AK ++P GN K EN + + ++ K C + D+ P
Sbjct: 7246 AKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPP 7305
Query: 1099 AFKQKLQDVHVAEGKKLL-LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
F +KL+ + + + +C++ P ++W + ++ + +S S+ + +
Sbjct: 7306 RFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM 7365
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
ED G Y C A N AG A S + V + PP+
Sbjct: 7366 HNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE---------------------PPIF--- 7401
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+KKP P K G V L ++ GT P +W K +++
Sbjct: 7402 -----RKKPHPIETLK------------------GADVHLECELQGTPPFHVSWYKDKRE 7438
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGS 1318
++ + K+ + + + IL G Y N +GS
Sbjct: 7439 LRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS 7479
Score = 50.1 bits (118), Expect = 2e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
G P + + VT LG++ +SC I G P P + W R GK L + + +++ +
Sbjct: 30530 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 30588
Query: 778 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
TL + + G Y + N VGE L+LQ
Sbjct: 30589 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 30623
Score = 49.7 bits (117), Expect = 3e-05
Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
V P+F +++ G + F C + G ++ W KD++ IR ++++ E+ +
Sbjct: 7210 VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVEN-TAT 7268
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L + V D +YTC A N G+ +C+A+L V+
Sbjct: 7269 LTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 7302
Score = 49.7 bits (117), Expect = 3e-05
Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)
Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
S P E + E P F L + VK G +TG+P+P++TW K ++ L+
Sbjct: 13673 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 13732
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
R+++ + I + D G Y VN G+A+ E+++
Sbjct: 13733 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 13792
Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
D N S + D ++TN + + DS
Sbjct: 13793 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 13827
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
P PP G P S+ +SW +GGS + Y +E + + W ++
Sbjct: 15599 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 15657
Query: 1385 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439
+ FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D
Sbjct: 15658 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 15715
Score = 49.7 bits (117), Expect = 3e-05
Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + L V PP I W+ L+ + + + E D G Y
Sbjct: 19708 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 19767
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
+N G+ E + V V D P PPV T + + P
Sbjct: 19768 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 19809
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
P II + ++ + K T C+ FR V N E
Sbjct: 19810 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 19852
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348
G + + EN+ G V P G +RS SS
Sbjct: 19853 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 19900
Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408
++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N
Sbjct: 19901 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 19959
Query: 1409 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
G P SE+T V +D+V D D K
Sbjct: 19960 ENGEGTP---SEITVVA------RDDVVAPDLDLK 19985
Score = 49.7 bits (117), Expect = 3e-05
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+
Sbjct: 23238 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 23296
Query: 789 AGQYEILLKNRVGECSCQVSLM 810
GQY I + N VG+ + + ++
Sbjct: 23297 GGQYGITVANVVGQKTASIEIV 23318
Score = 49.7 bits (117), Expect = 3e-05
Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G
Sbjct: 25117 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 25174
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
Y + N SG S +A ++++ LDS + +RE K + D ++TN
Sbjct: 25175 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 25232
Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
I ++ + A + NC+ Q G S + + + E+ +
Sbjct: 25233 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 25292
Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
+ P P + T +T A ++ E + G V + K + T
Sbjct: 25293 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 25352
Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431
GL G + V AA R P E KP + VK + +
Sbjct: 25353 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 25412
Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
K G P+ V W +G + ++ + V L + +A D GTY SN
Sbjct: 25413 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 25471
Query: 492 AQGQLSCSWTLQV 504
+ G ++ T+ V
Sbjct: 25472 SAGSITVPITIIV 25484
Score = 49.3 bits (116), Expect = 4e-05
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F K I + G A F ++G V W KD I E + ++ + E+ SL
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTF-ENNVASLY 4544
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+S + D KY C+A N G C+A L V+
Sbjct: 4545 LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK 4576
Score = 49.3 bits (116), Expect = 4e-05
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 19364
Query: 230 VYTCLVVNGSGKASMSAELSI 250
YT N SG S + +L +
Sbjct: 19365 DYTITAENSSGSKSATIKLKV 19385
Score = 48.9 bits (115), Expect = 5e-05
Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)
Query: 1131 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D
Sbjct: 20413 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 20472
Query: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
P PP S+ + +K TPP I + +++
Sbjct: 20473 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 20512
Query: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310
E+ L W + IQ H+ + + G++ + H G
Sbjct: 20513 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 20553
Query: 1311 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
G + +VD+ P P P S++ ++ T+SW DGGS + Y +
Sbjct: 20554 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 20608
Query: 1369 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426
E + + W + V L Y+FRV A N G PS+ S+ + +
Sbjct: 20609 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 20668
Query: 1427 K--PEEPKDEVEVSDDDEK 1443
P P V+D +K
Sbjct: 20669 AAYPPGPPSNPHVTDTTKK 20687
Score = 48.5 bits (114), Expect = 6e-05
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)
Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
I++T++++ P S P+T A +PPR L +K G + V G P P
Sbjct: 19267 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 19325
Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++
Sbjct: 19326 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 19382
Query: 121 LTV 123
L V
Sbjct: 19383 LKV 19385
Score = 48.5 bits (114), Expect = 6e-05
Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)
Query: 1325 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
+ +D PP P +D +S++L+W +GGS V Y IE+ W +
Sbjct: 30024 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 30081
Query: 1383 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
C +T +++ H EY+FRV A N G EP++ V E E P E++
Sbjct: 30082 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 30139
Score = 48.1 bits (113), Expect = 8e-05
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566
+ + PS ++ G+D ++ V G P P I+W+ +G+P+ Q R E A
Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 24367
Query: 567 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
LHI++ +D G YT A N+ G + + V V EK
Sbjct: 24368 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 24404
Score = 48.1 bits (113), Expect = 8e-05
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QLG PV+++ +E +PS+ E P F T VK + + GRP
Sbjct: 25380 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 25422
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ +
Sbjct: 25423 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 25480
Query: 249 SIQGLD 254
+I LD
Sbjct: 25481 TIIVLD 25486
Score = 48.1 bits (113), Expect = 8e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)
Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
C TN ELT + + + V ++ D S P+ T P I + PP+
Sbjct: 25734 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 25789
Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
+ +VVK G++ + + I GRP P ++W K + ++ AR + + +L +
Sbjct: 25790 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 25849
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ D G Y + N +G S++ +
Sbjct: 25850 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 25879
Score = 48.1 bits (113), Expect = 8e-05
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)
Query: 1700 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1759
AV + + S M S + KS L++ + + ++ A LE + E+
Sbjct: 32495 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 32554
Query: 1760 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
T+ R + V EG +ARF C +G P P V W + Q + S Q+ +
Sbjct: 32555 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 32613
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ IS V D+ Y+ NS G+ L ++
Sbjct: 32614 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 32651
Score = 47.8 bits (112), Expect = 1e-04
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1808
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1696 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1754
Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+E G CSL D TC+A N G +A LIV+
Sbjct: 1755 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1795
Score = 47.8 bits (112), Expect = 1e-04
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F K LEV+ G F I G P +V WF+ + + + I Y ED L
Sbjct: 5893 PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNI-YFEDTVAELE 5951
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ ++ +YTC N+ G+A+CT L V+
Sbjct: 5952 LFNIDISQSGEYTCVVSNNAGQASCTTRLFVK 5983
Score = 47.8 bits (112), Expect = 1e-04
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 1263 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322
G P+T ++ ++++ KV + + T+ Q + + NK G +
Sbjct: 13515 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573
Query: 1323 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376
VN+ T PDPP D ++S+ L+W DGGS ++ Y +E +
Sbjct: 13574 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 13632
Query: 1377 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
W T V L Y +RV+A+N G S+PS+ +E + E P+ +
Sbjct: 13633 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 13692
Query: 1436 EV 1437
+V
Sbjct: 13693 DV 13694
Score = 47.8 bits (112), Expect = 1e-04
Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%)
Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478
K ++ + G P P+ +W +G + ++G ++ EDA S + + + +
Sbjct: 15823 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 15882
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531
+G YS TA N GQ + + ++V + L V ++ + +G D
Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 15941
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
++G + + T ++G+ C G + D L E + AEN G
Sbjct: 15942 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 15992
Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
V ++ ++R P+ P P +K+ G TV +S PP
Sbjct: 15993 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 16035
Query: 652 PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
+ W G + + + ++ + ++++ + +A
Sbjct: 16036 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 16094
Query: 699 NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756
N+AG + A + + P I + G +V I I G PFPT+ W +
Sbjct: 16095 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 16154
Query: 757 ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
D K H L +D TLV+ + + G Y I N +G S ++ L
Sbjct: 16155 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 16211
Score = 47.8 bits (112), Expect = 1e-04
Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)
Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630
P D + +A NA+G +S S+ S ++ V P P + GL
Sbjct: 27920 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 27969
Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
+ G + + V G P P V W +G EI++ + SL +++ +
Sbjct: 27970 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 28026
Query: 691 GTYTCEAWNSAGEVRTQAVLTVQE 714
G YT EA N++G + + + VQ+
Sbjct: 28027 GVYTVEAKNASGSAKAEIKVKVQD 28050
Score = 47.4 bits (111), Expect = 1e-04
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
++ + P F++ ++D+E G C++ G +V W++D +R+ + Q + D
Sbjct: 6169 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSF-VD 6227
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1846
+L I +Y+C A N LG A+ +A L
Sbjct: 6228 NVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 6262
Score = 47.4 bits (111), Expect = 1e-04
Identities = 47/244 (19%), Positives = 83/244 (34%), Gaps = 35/244 (14%)
Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85
S+ E P F+ + G + V G+ V W ++ + I
Sbjct: 6544 SVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFI 6603
Query: 86 RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
+L + + + GKY C+ N +G R+ + LTV
Sbjct: 6604 DNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLE-------------------- 6643
Query: 146 APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
P + K + V G C +TG P+ W K L +
Sbjct: 6644 --------------PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADS 6689
Query: 206 RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
+ ++ N + L+I D G+Y+ V N GK++ + + + SF+R+ K
Sbjct: 6690 KHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSD-RIVPPSFIRKLK 6748
Query: 266 ATNS 269
N+
Sbjct: 6749 DVNA 6752
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
+++P PP +SD SS+ L W DGGS + Y IE + W +
Sbjct: 13289 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 13347
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
++ V L ++Y +RV A N G S+PS+ T + EP ++ D
Sbjct: 13348 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 13402
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)
Query: 574 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632
+P++ T T L E A Q A V+ S S+ + +A + P + + S L
Sbjct: 19246 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 19305
Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689
V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D
Sbjct: 19306 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 19362
Query: 690 TGTYTCEAWNSAG 702
+G YT A NS+G
Sbjct: 19363 SGDYTITAENSSG 19375
Score = 47.4 bits (111), Expect = 1e-04
Identities = 25/82 (30%), Positives = 36/82 (43%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
+ KE R I G+P P V+W KG PL RVSV L ++ + D G
Sbjct: 19993 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 20052
Query: 231 YTCLVVNGSGKASMSAELSIQG 252
YT + N +G + + + G
Sbjct: 20053 YTITLKNVAGTKEGTISIKVVG 20074
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T
Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 24367
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
L I +++D GKYT ATN +G + + V
Sbjct: 24368 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 1731 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 27932 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 27991
Query: 1791 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 27992 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049
Score = 47.4 bits (111), Expect = 1e-04
Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
I+ G+ + V G PEP++ W + + + + L G R T VI D G
Sbjct: 29059 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 29116
Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
KYT N SG + V+V + V S G+ VS+ ++ +S P + I
Sbjct: 29117 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 29175
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
+ T V+ EG+ S +T + +V + P P + +N
Sbjct: 29176 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 29235
Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
+ G+ ++ G ++ ++ E+S +D + +R T+
Sbjct: 29236 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 29295
Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
D R +VT+++ + C R + A NS+P S SC++
Sbjct: 29296 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 29338
Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
P +AP+ V+ T SI+L + + +G + E+ A
Sbjct: 29339 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 29396
Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420
R F +G + AA + ++G + + E +P
Sbjct: 29397 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 29453
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479
++ ++ +++ VSG P P + W +G + S + + S+ L ++ K
Sbjct: 29454 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 29509
Query: 480 RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
D+G Y+ A N G+ S + ++V + V EV+ ++ + I+G
Sbjct: 29510 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 29565
Query: 533 LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590
G PV I + T + I + + L EN G
Sbjct: 29566 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 29619
Query: 591 --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
S V V E +P+ P+K L+V+D ++ T+T ++
Sbjct: 29620 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 29655
Query: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705
P L++G + GT+ + + + P E T T E +R
Sbjct: 29656 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 29710
Query: 706 TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752
Q V EP + + R ++ G+ V + IAG P P
Sbjct: 29711 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 29770
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
W G L +++ V + V L +++ G+Y + LKN G S + +++
Sbjct: 29771 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 29829
Query: 813 NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
+ A ++ EP + GG G ++ + RPGW
Sbjct: 29830 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 29879
Score = 47.4 bits (111), Expect = 1e-04
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387
P PP G P + + W DGG+ + +Y ++ + + W + T
Sbjct: 29240 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 29298
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
V L+ +Y+FRV A+N G SEPS+ S + E P
Sbjct: 29299 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 29342
Score = 47.4 bits (111), Expect = 1e-04
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
V + S S++ ++P +P E + + + I+ GA+ + V G P P
Sbjct: 29420 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 29477
Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V
Sbjct: 29478 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 29534
Score = 47.0 bits (110), Expect = 2e-04
Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)
Query: 1111 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169
EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+
Sbjct: 31581 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 31640
Query: 1170 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228
C ND G+ ++ V + + RR T+KK K
Sbjct: 31641 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 31680
Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285
T PP+ ++ GE+V +T TW K ++I+ ++ K
Sbjct: 31681 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 31740
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334
E+ + +LTI + + YT++ NK G + LTV P P
Sbjct: 31741 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 31800
Query: 1335 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
G +IR S + TL W DG +IEI +
Sbjct: 31801 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 31851
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
+ +++D LP+ +RV A N G++ ++ + K +E K + E +K+
Sbjct: 31852 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 31908
Query: 1445 PEVDYRTVTI 1454
+ R I
Sbjct: 31909 IDKTLRMAEI 31918
Score = 46.6 bits (109), Expect = 2e-04
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 29/217 (13%)
Query: 1651 CYILNRLDCTQCLQH------PWLMKDTKNMEAKKLSKDRMKKYMARR-----KWQKTGN 1699
C N+ QC H P+ ++ ++ + ++ ++K + KW K
Sbjct: 4747 CSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNK 4806
Query: 1700 -----AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV--AEE 1752
A R++ + + + + + + +G+ L+ DV A +A +E
Sbjct: 4807 ELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLS-------NDVGTATSKATLFVKE 4859
Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
P + K L + G + F+C+I G P V W+ D I + I + DG
Sbjct: 4860 PPQ---FIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISF-IDG 4915
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ IS ++ Y C+A N G A+C+ EL V+
Sbjct: 4916 LATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 4952
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/95 (24%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Query: 1756 VKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
+ P F+K + + +E EG++ + + ++ G V W+K++ I+ + + +I + ++
Sbjct: 8247 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITF-KNNTL 8305
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L + +D YTCK N G A CT+ ++++
Sbjct: 8306 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 8340
Score = 46.2 bits (108), Expect = 3e-04
Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444
GLG D IP+E Q P E + E VK TV+F + G+P P
Sbjct: 17489 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 17541
Query: 445 VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504
W +G+ ++ E V D S L + RD+G Y T SNA G + + L V
Sbjct: 17542 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
LP KE + + + ++G P P V+W + P+ + R ++ T +L+++
Sbjct: 19987 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 20045
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125
+ D GKYT N +G ++ T+ + V G
Sbjct: 20046 QKSDAGKYTITLKNVAGTKEGTISIKVVG 20074
Score = 46.2 bits (108), Expect = 3e-04
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 1717 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1771
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 32681 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 32740
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 32741 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 32791
Query: 1832 K 1832
+
Sbjct: 32792 E 32792
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I +
Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2510
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188
D G YK + G+ E +C ++V+
Sbjct: 2511 DEGPYKLI----VGRVETNCNLSVE 2531
Score = 45.8 bits (107), Expect = 4e-04
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1816
P F K + D + G A +EG+ VVW KD + IRES + +I + D +L
Sbjct: 6551 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISF-IDNIATL 6609
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+ + KY C+ N G C+A L V
Sbjct: 6610 QLGSPEASNSGKYICQIKNDAGMRECSAVLTV 6641
Score = 45.8 bits (107), Expect = 4e-04
Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
Query: 1748 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
++ ++P P F + + + V EG + C ++G + W K + I+ S
Sbjct: 8336 SIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFS 8395
Query: 1808 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ G L + DV D Y CKA N G T +++ ++
Sbjct: 8396 F-ASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK 8436
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 12372 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 12427
Query: 1814 CSLIISDVCGDDDAKYTCK 1832
L+I+ DD+A+Y+C+
Sbjct: 12428 RILVINKCLLDDEAEYSCE 12446
Score = 45.8 bits (107), Expect = 4e-04
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565
++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G
Sbjct: 27957 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 28013
Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
L ++DA + G YT A+NA G V V +
Sbjct: 28014 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 28050
Score = 45.4 bits (106), Expect = 5e-04
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3054 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3110
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ L+I D KYT A G TA+L VE
Sbjct: 3111 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3143
Score = 45.4 bits (106), Expect = 5e-04
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F +T +EV+ G + F I G P +V WFK + + I ED L
Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISL-EDFVTELE 6892
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ +V + Y+C N G A+CT L V+
Sbjct: 6893 LFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924
Score = 45.4 bits (106), Expect = 5e-04
Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%)
Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
RQ TV+ EG+ K V + G P ET+P E A +L G
Sbjct: 15059 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 15113
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ + G+ R +TGRP P W K L RV + L I + D G
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 15172
Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
Y N G +A L ++ + + + + D E+T I
Sbjct: 15173 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 15232
Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
K++K+ + +E + + G + ++ + PP E D
Sbjct: 15233 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 15292
Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
P T+P+ ++T S+ITL EPR+ G + E++R P
Sbjct: 15293 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 15348
Query: 382 FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423
PT + + D KA N +P+ Q D P + + +
Sbjct: 15349 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 15408
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478
+VK + V +V+G+P P++ W T + + ++++ ++ S L + KA
Sbjct: 15409 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 15468
Query: 479 TRDSGTYSCTASNAQGQL 496
D GTY+ TASN G +
Sbjct: 15469 REDKGTYTVTASNRLGSV 15486
Score = 45.4 bits (106), Expect = 5e-04
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%)
Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567
+V P+FSS +V GQD ++ + G P P ITW +G P++ T +
Sbjct: 23231 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 23286
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I++ +D G Y N +GQ + S + +K P P P+
Sbjct: 23287 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 23333
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPP 651
+S ++ +S NPP
Sbjct: 23334 DVS----------AESITLSWNPP 23347
Score = 45.4 bits (106), Expect = 5e-04
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
+ G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y
Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382
Query: 694 TCEAWNSAG-EVRTQAVLTVQEP 715
T A NSAG +V+ +++P
Sbjct: 24383 TVTATNSAGTATENLSVIVLEKP 24405
Score = 45.1 bits (105), Expect = 7e-04
Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+K G + E V G P P + W ++G+ + + + T +LV D G
Sbjct: 21473 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 21531
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160
YT ATN G FAK + V G + V + + P
Sbjct: 21532 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 21578
Query: 161 P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215
P K+ +V++ + R + + QVT LK L+ + RV K G+
Sbjct: 21579 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 21637
Query: 216 -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256
VL ++ D + C S S ++ D A
Sbjct: 21638 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 21697
Query: 257 NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315
+ +++ K T +D+R +V+ + E + + A + SP +P
Sbjct: 21698 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 21757
Query: 316 PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366
PP + L++ + S A P+ S PE P A GL S
Sbjct: 21758 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 21816
Query: 367 SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423
+ + + GLG +V KA +R +P E + D+ K +
Sbjct: 21817 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 21871
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481
++ T++ + G P PEV W + E + ++ S Y L+ D
Sbjct: 21872 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 21925
Query: 482 SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
SG Y T N+ G S ++V + L V EV + ++ D +++G +
Sbjct: 21926 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 21985
Query: 535 CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593
V R + + C ++ D L E Y LAEN G +
Sbjct: 21986 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 22034
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
A K S R P+ P K T +MD ++ +V +S P
Sbjct: 22035 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 22073
Query: 654 VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
H+G + +G+ + + C E T T + + V Q +
Sbjct: 22074 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 22129
Query: 713 QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
+P + P I+K + T G+ + + G P P V W +D L
Sbjct: 22130 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 22188
Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
K T E+ L +K G Y + L N GE
Sbjct: 22189 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 22228
Score = 45.1 bits (105), Expect = 7e-04
Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)
Query: 1228 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284
P PP A P++ + +R E G I W+ K R I +
Sbjct: 28837 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 28891
Query: 1285 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
KV E K+T L E+ Y L + +A + + D P G P +D+
Sbjct: 28892 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 28950
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398
S+++L W +YDGGS V Y IE + + + W + F V L
Sbjct: 28951 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 29010
Query: 1399 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
Y+FRV A N G S+ S+ + T ++ PK E++
Sbjct: 29011 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 29049
Score = 44.7 bits (104), Expect = 9e-04
Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%)
Query: 656 WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
W+ +G+ I+ES F G L I +V D G YTC E + A L V+E
Sbjct: 11151 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210
Query: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
+ + VT GQ + +SC + + V W +DGK + + G
Sbjct: 11211 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 11265
Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810
+ L + AG Y + ++N ECS V ++
Sbjct: 11266 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 11301
Score = 44.7 bits (104), Expect = 9e-04
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386
P P G P D+ S+++L W +DGGS + Y +E W T
Sbjct: 19189 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 19248
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
+ L +Y+FR A S PS+ S+ T+ + P+ ++ V+
Sbjct: 19249 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 19300
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
L +K G T +F +RG P P W +G I + + ++ FS L I
Sbjct: 17520 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 17576
Query: 100 DRGKYTCEATNGSGARQVTVELTV 123
D G+Y +N +G++ V V LTV
Sbjct: 17577 DTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)
Query: 601 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
+EK S + +PV A P F + V+ G + + V G P P V W +
Sbjct: 22125 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 22184
Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718
++++ + E L I++ ED G Y + NSAGE + T V+ + +P
Sbjct: 22185 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 22244
Query: 719 TQP 721
T P
Sbjct: 22245 TGP 22247
Score = 43.9 bits (102), Expect = 0.001
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
+ V G +CK+ G P+ V W+KD + + S+ + + + SL I V D
Sbjct: 5713 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLRILSVERQDA 5771
Query: 1827 AKYTCKAVNSLGEATCTA 1844
YT + N++G+++CTA
Sbjct: 5772 GTYTFQVQNNVGKSSCTA 5789
Score = 43.9 bits (102), Expect = 0.001
Identities = 54/235 (22%), Positives = 90/235 (38%), Gaps = 42/235 (17%)
Query: 20 DPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRF 79
D S ++ + P F P + +G+ + + G P +V W ++ + + + +F
Sbjct: 6445 DASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKF 6504
Query: 80 LLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPVVS 137
+ T SL I + D G+Y C+ATN GS +V+ F K+L S
Sbjct: 6505 KITSKHFDT-SLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSD--TS 6561
Query: 138 KTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK- 196
+GD AVE R + G P V WLK
Sbjct: 6562 TLIGD-----AVELRAIVEGFQP-----------------------------ISVVWLKD 6587
Query: 197 -GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
G V ++ S +S + + L++ + G Y C + N +G SA L++
Sbjct: 6588 RGEV-IRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTV 6641
Score = 43.9 bits (102), Expect = 0.001
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
++V G +C + G P+ WFKD + + ++I + + L I +V D
Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS-GLKIINVAPSDS 7653
Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
Y+ + N +G+ +CTA L V
Sbjct: 7654 GVYSFEVQNPVGKDSCTASLQV 7675
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F + ++V+ G+ F ++G P V WFK + + ED L
Sbjct: 7775 PSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSL-EDSVAELE 7833
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ DV +YTC N G+A+CT L ++
Sbjct: 7834 LFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 7865
Score = 43.9 bits (102), Expect = 0.001
Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+V+ G R + GRP P+VTW K + + V + M L I +DD G
Sbjct: 18616 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 18674
Query: 230 VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279
Y+ +VN +G+ ++ + + + S V +T +D +VT+ I
Sbjct: 18675 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 18734
Query: 280 SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311
++ + D A P P A++
Sbjct: 18735 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 18794
Query: 312 --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365
S+P PPR+ ++ + T P L+ K IT QP R V+
Sbjct: 18795 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 18854
Query: 366 ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413
G++ K R A + P G V +A + +P
Sbjct: 18855 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 18899
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
PK P+ +K + ++ V G P P W +G + V++ S L
Sbjct: 18900 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 18957
Query: 474 LLKARTRDSGTYSCTASNAQG 494
+ +DSG YS TA N+ G
Sbjct: 18958 IKDVTRKDSGYYSLTAENSSG 18978
Score = 43.9 bits (102), Expect = 0.001
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L
Sbjct: 18899 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 18957
Query: 220 IHGVNQDDVGVYTCLVVNGSG 240
I V + D G Y+ N SG
Sbjct: 18958 IKDVTRKDSGYYSLTAENSSG 18978
Score = 43.5 bits (101), Expect = 0.002
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
KP+F K + ++ +C+++ V W KD Q + + ++I + ED +L
Sbjct: 3643 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICF-EDKIATL 3701
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
I D Y C A N G ++C+A + V
Sbjct: 3702 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 3733
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)
Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
VK V ++ +SK S +V P R D P + F+ ++EG +++G P
Sbjct: 16091 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 16144
Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
P +TW + N +P+ T + ++D T +LVI D G YT A N
Sbjct: 16145 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 16200
Query: 111 GSGARQVTVELTVEG 125
G + L V G
Sbjct: 16201 NLGTASKEMRLNVLG 16215
Score = 43.1 bits (100), Expect = 0.003
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2883 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2940
Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2941 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2984
Score = 43.1 bits (100), Expect = 0.003
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1819
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 16126 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 16184
Query: 1820 DVCGDDDAKYTCKAVNSLGEAT 1841
D YT AVN+LG A+
Sbjct: 16185 QSRRSDTGLYTITAVNNLGTAS 16206
Score = 43.1 bits (100), Expect = 0.003
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
Y N SG A SA +++ LD + K TN V KE IS E+ LD+
Sbjct: 17978 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 18028
Score = 43.1 bits (100), Expect = 0.003
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 18888 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 18947
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 18948 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 18988
Score = 43.1 bits (100), Expect = 0.003
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 1731 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1787
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 22517 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 22573
Query: 1788 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 22574 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 22632
Query: 1848 V 1848
V
Sbjct: 22633 V 22633
Score = 43.1 bits (100), Expect = 0.003
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390
P PP S + S+TL W DGGS + Y IE + + W +
Sbjct: 25983 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 26041
Query: 1391 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421
V+ L EY++RV A N G S PS+ S L
Sbjct: 26042 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 26074
Score = 42.7 bits (99), Expect = 0.003
Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)
Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150
+G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G
Sbjct: 2263 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2319
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
+++++ ED+G Y V
Sbjct: 2320 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2339
Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
+ G ++ +K KP P I+Q DQKV G+ V+L KV+ + +
Sbjct: 2340 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2387
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD
Sbjct: 2388 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2447
Query: 1331 PDP 1333
P
Sbjct: 2448 ITP 2450
Score = 42.7 bits (99), Expect = 0.003
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 1760 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1813
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 11117 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 11174
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
+I DV D +YTC E T TA+L+VE +
Sbjct: 11175 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)
Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
+ + TV G Q + V++K S P+ T P + PKF
Sbjct: 23576 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 23634
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
+VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D
Sbjct: 23635 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 23692
Query: 228 VGVYTCLVVNGSGKASMSAELSI 250
G Y N +G S + +
Sbjct: 23693 GGQYILRASNVAGSKSFPVNVKV 23715
Score = 42.4 bits (98), Expect = 0.004
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107
+KS K +++ K + + +N + H G + + T+ A F++ ++D+
Sbjct: 3008 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3067
Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167
V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G
Sbjct: 3068 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3126
Query: 1168 YKCVAKNDAGQAE 1180
Y VA + A+
Sbjct: 3127 YTVVAGGNVSTAK 3139
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
+K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y
Sbjct: 17230 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 17287
Query: 232 TCLVVNGSGKASMSAELSI 250
+ V N +G ++S ++ +
Sbjct: 17288 SLTVENPAGSKTVSVKVLV 17306
Score = 42.4 bits (98), Expect = 0.004
Identities = 21/72 (29%), Positives = 34/72 (47%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++++ G R + GRP P++TW K NV L+ + + + L VN+ D G
Sbjct: 19703 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 19762
Query: 230 VYTCLVVNGSGK 241
Y + N GK
Sbjct: 19763 KYILTLENSCGK 19774
Score = 42.4 bits (98), Expect = 0.004
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + + V G P P V W +++++ +FE T L I E D+G Y
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 21139
Query: 697 AWNSAGEVRTQAVLTVQ 713
A N GEV V+T+Q
Sbjct: 21140 ARNIVGEVGD--VITIQ 21154
Score = 42.4 bits (98), Expect = 0.004
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576
KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+
Sbjct: 22550 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 22609
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633
D G Y A+N G+ S VTV+ K R P P P+ + G++ K
Sbjct: 22610 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 22656
Query: 634 -----VMDGSQVTMTVQVSGNPPPEVIW 656
+ DG + V ++W
Sbjct: 22657 AWKPPLQDGGSDIINYIVERRETSRLVW 22684
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 23229 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 23283
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
+L I + DD +Y N +G+ T + E++
Sbjct: 23284 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 23318
Score = 42.4 bits (98), Expect = 0.004
Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 736 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795
+ + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+
Sbjct: 25410 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 25468
Query: 796 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
+ N G + +++++ + P + SC+ +
Sbjct: 25469 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 25504
Score = 42.0 bits (97), Expect = 0.006
Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158
F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I
Sbjct: 12287 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 12344
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
PED Y C DA + SC + V
Sbjct: 12345 DCTPEDIKTYTC----DAKDFKTSCNLNV 12369
Score = 42.0 bits (97), Expect = 0.006
Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E F N+ + E T K V P +V W++ + I GR+ + R
Sbjct: 12459 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 12517
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
LVI H ED G Y C + +V V
Sbjct: 12518 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 12548
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
E +F +K + + EG+ F C I+ P V W + + L+ +
Sbjct: 12549 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 12598
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V +VL + D+G Y +V G A +A L++
Sbjct: 12599 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 12636
Score = 42.0 bits (97), Expect = 0.006
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578
G+ + V G P+P+I W N I+ + EL I A+ ED
Sbjct: 15413 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 15472
Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKS 605
GTYT A N LG V + V V+++ S
Sbjct: 15473 GTYTVTASNRLGSVFRNVHVEVYDRPS 15499
Score = 42.0 bits (97), Expect = 0.006
Identities = 26/93 (27%), Positives = 39/93 (41%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
P+ + ++ + L V G+ V + G P P W +G+EI+ E + E
Sbjct: 17508 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 17567
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
L I+ DTG Y N+AG LTV
Sbjct: 17568 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 42.0 bits (97), Expect = 0.006
Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%)
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
V G P P+V W G ++G +++ + +L + + DSG YS T N G+
Sbjct: 18630 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 18687
Query: 497 SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
+ ++V L V +V + V +G V V R TW
Sbjct: 18688 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 18745
Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
+ T E H+ + +P + + A N G V K S
Sbjct: 18746 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 18793
Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666
+ L S+P P + ++ +++T PP L +G +
Sbjct: 18794 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 18835
Query: 667 ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716
E+ R T++S+ ++++ TG + A N+ G + V E
Sbjct: 18836 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 18894
Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
+ P I P +T G+ + I + G P PT W + G+ + H V + +
Sbjct: 18895 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 18953
Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
L++K V +G Y + +N G + ++ +++ ++ P
Sbjct: 18954 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 18997
Score = 42.0 bits (97), Expect = 0.006
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+T G +V + + G P PTV W +DG L K ++ ++ TL L V +
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 19363
Query: 790 GQYEILLKNRVGECSCQVSL 809
G Y I +N G S + L
Sbjct: 19364 GDYTITAENSSGSKSATIKL 19383
Score = 42.0 bits (97), Expect = 0.006
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
VV+ G R GRP P W K + L S R + + L + N++D G
Sbjct: 28368 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 28425
Query: 231 YTCLVVNGSGKASMSAELSI 250
YT V N SG S++ + +
Sbjct: 28426 YTLTVENNSGSKSITFTVKV 28445
Score = 42.0 bits (97), Expect = 0.006
Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639
+ LA+NA G +S + T + + EY AP K L G DL + GS
Sbjct: 29014 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 29064
Query: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
+ + V G P P++IW E+ E + G + + I+ D+G YT N
Sbjct: 29065 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 29124
Query: 700 SAGEVRTQAVLTVQEPHDGTQP 721
++G T+AV + + D P
Sbjct: 29125 ASG---TKAVSVMVKVLDSPGP 29143
Score = 42.0 bits (97), Expect = 0.006
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
T D ++ P E + G+ V ++ G + G+P+P++ W KG+
Sbjct: 29036 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 29085
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
L +VS+ I ++ D G YT V N SG ++S + + LDS
Sbjct: 29086 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 29140
Score = 41.6 bits (96), Expect = 0.007
Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
+N+ + E TA FE V + P + W +NG I +F + ++G L+I
Sbjct: 2889 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2945
Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
ED +YT N + +TV E+TV EG K L
Sbjct: 2946 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 3005
Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
V K+ GD F A + +++ E +F +
Sbjct: 3006 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3065
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
+ V E + F C+++ P V W+K + LQ + R+ + ++ + L I D
Sbjct: 3066 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3124
Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
G YT + +G +A+L ++G D RS +E +
Sbjct: 3125 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3157
Score = 41.6 bits (96), Expect = 0.007
Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V + Q + CE++ + +V W +G V + G I L + A D+GT
Sbjct: 11224 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 11281
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+ T NA L CS ++V V + ++D V + C + P
Sbjct: 11282 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 11335
Query: 545 ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
I W + +P + L I++A+PED Y E A +T
Sbjct: 11336 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 11391
Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
+ E R+ E L P+ D+ + + + ++S P W
Sbjct: 11392 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 11432
Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
G ++ S + G + L + +V + G +A N+ T A+LTV+E
Sbjct: 11433 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 11484
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
+ F + VT + C + + V W + G + K + F+++ + L
Sbjct: 11485 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 11541
Query: 780 VLKKVQPWHAGQY 792
V+ Q G Y
Sbjct: 11542 VINDSQFDDEGVY 11554
Score = 41.6 bits (96), Expect = 0.007
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 12522
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1862
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 12523 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 12570
Score = 41.6 bits (96), Expect = 0.007
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
A+ ISK S S P + + E P + P+ + + G T + E V G P P +
Sbjct: 23600 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 23657
Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
W R + I R C I+ T L++ D G+Y A+N +G++ V +
Sbjct: 23658 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 23713
Query: 122 TV 123
V
Sbjct: 23714 KV 23715
Score = 41.6 bits (96), Expect = 0.007
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++VK G + GRP P V W K + L+ A V ++ L I N++D G
Sbjct: 26196 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 26253
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
YT + N AS++ L ++ LD+ T T DV KE
Sbjct: 26254 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 26292
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+K ++++ + V G P P V WF +G + ++ ++E+ + GS L + A G
Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 28028
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514
Y+ A NA G ++V+ V P
Sbjct: 28029 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 28058
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1813
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 33385
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
+LII DV D YT N G + T + + ++
Sbjct: 33386 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 33423
Score = 41.2 bits (95), Expect = 0.010
Identities = 24/96 (25%), Positives = 43/96 (44%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+C P + ++V EG+ P P V+W K ++ S R+++ +
Sbjct: 14384 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 14443
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
LE+ + D G+YT + N G A+ S + + GL
Sbjct: 14444 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 14479
Score = 41.2 bits (95), Expect = 0.010
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Query: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570
P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L +
Sbjct: 14387 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 14446
Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTV 600
++ D G YT EN LG + S V V
Sbjct: 14447 PKSVRADAGIYTITLENKLGSATASINVKV 14476
Score = 41.2 bits (95), Expect = 0.010
Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%)
Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454
VSK + P + QR P + K + EV+E V ++ G+P P + WF P
Sbjct: 16099 VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 16155
Query: 455 RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
++ + V D + L C L ++R D+G Y+ TA N G S L V
Sbjct: 16156 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 16215
Query: 507 LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557
V P F SV D + +G + + R TW+ ++ +P
Sbjct: 16216 RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 16271
Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
C + +L L + +A+N G + + + ++ + +P AP
Sbjct: 16272 -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 16320
Query: 618 SKPT 621
KPT
Sbjct: 16321 DKPT 16324
Score = 41.2 bits (95), Expect = 0.010
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 17515 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 17573
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIV 1848
D +Y N+ G T L V
Sbjct: 17574 LRRDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 41.2 bits (95), Expect = 0.010
Identities = 23/80 (28%), Positives = 36/80 (45%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+ G++ ++ I G P P V W +DGK L + E+ TLV+K
Sbjct: 24717 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 24776
Query: 790 GQYEILLKNRVGECSCQVSL 809
GQY + L N G S +++
Sbjct: 24777 GQYILKLSNVGGTKSIPITV 24796
Score = 41.2 bits (95), Expect = 0.010
Identities = 26/85 (30%), Positives = 34/85 (40%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V + G L+L V P IIWT K L + + L G + I+ D G
Sbjct: 29057 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 29116
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191
Y KN +G S V V D+P
Sbjct: 29117 KYTLTVKNASGTKAVSVMVKVLDSP 29141
Score = 40.8 bits (94), Expect = 0.012
Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F K + D V GS + G P V W KD+ I +S I E I+
Sbjct: 6929 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 6988
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
+D A+Y+C N G+ C E +V +E
Sbjct: 6989 STI-EDYAQYSCLIENEAGQDIC--EALVSVLE 7018
Score = 40.8 bits (94), Expect = 0.012
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Query: 604 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W
Sbjct: 13671 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 13730
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+++ + E + ++ I + DTGTY EA N G R AV+ V
Sbjct: 13731 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 13778
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 13695 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 13753
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIV 1848
D Y +AVN G AT E+ V
Sbjct: 13754 KRSDTGTYIIEAVNVCGRATAVVEVNV 13780
Score = 40.8 bits (94), Expect = 0.012
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389
P PP + I ++ L W DGGS + +Y +E D K W+ + T + T
Sbjct: 14084 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 14142
Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSE 1414
V L Y FRV A N G S+
Sbjct: 14143 TVTPLTEGSLYVFRVAAENAIGQSD 14167
Score = 40.8 bits (94), Expect = 0.012
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P IL P + IK G + E V G P P W + + + + + L+
Sbjct: 18899 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 18957
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I V +D G Y+ A N SG +++ V
Sbjct: 18958 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 18988
Score = 40.8 bits (94), Expect = 0.012
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%)
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
++ +A N +G +S L V +A + + P+F + V+ G+D + G P
Sbjct: 22118 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 22176
Query: 543 PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
P +TW + P+ Q R E+ + L I+DA ED G Y N+ G+ + V
Sbjct: 22177 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 22236
Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPI 624
V +K P PT P+
Sbjct: 22237 VLDK-------------PGPPTGPV 22248
Score = 40.8 bits (94), Expect = 0.012
Identities = 20/81 (24%), Positives = 39/81 (48%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G
Sbjct: 22553 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 22612
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y N +G+ S++ + +
Sbjct: 22613 NYILKAKNVAGERSVTVNVKV 22633
Score = 40.8 bits (94), Expect = 0.012
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+
Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 23299
Query: 104 YTCEATNGSGARQVTVEL 121
Y N G + ++E+
Sbjct: 23300 YGITVANVVGQKTASIEI 23317
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 24310 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 24368
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I + DD KYT A NS G AT +IV
Sbjct: 24369 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/74 (31%), Positives = 33/74 (44%)
Query: 639 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
Q+ + V G P V W +G ++E+ + T SL I+E ED GTY
Sbjct: 25411 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 25470
Query: 699 NSAGEVRTQAVLTV 712
NSAG + + V
Sbjct: 25471 NSAGSITVPITIIV 25484
Score = 40.8 bits (94), Expect = 0.012
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)
Query: 711 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757
+V EP + T P + PR + G+ + I+ IAG P P + W +D
Sbjct: 25767 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 25826
Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
G + ++ E++ ++ L +K GQY + LKN G S V+
Sbjct: 25827 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 25876
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 12287 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 12344
Query: 1820 DVCGDDDAKYTCKA 1833
D +D YTC A
Sbjct: 12345 DCTPEDIKTYTCDA 12358
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ ++ G T + RV+G PEP +TW + G+ + R L + L I D
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 17976
Query: 102 GKYTCEATNGSGARQ 116
GKY A N SG Q
Sbjct: 17977 GKYIISAKNSSGHAQ 17991
Score = 40.4 bits (93), Expect = 0.016
Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V+ QT++ V G P+P++ W EG + R E +++ +D L + +A D G
Sbjct: 17920 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 17978
Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
Y +A N+ G S + V + L V V ++ + + G + V
Sbjct: 17979 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 18038
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596
+P Q S + V + I+ + L + + AEN +G
Sbjct: 18039 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 18082
Query: 597 WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650
T+ K +L + P +P P +L + D + + ++ G
Sbjct: 18083 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 18130
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705
P + H ++ S+D+ +G+ + + + + N GE V+
Sbjct: 18131 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 18188
Query: 706 TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763
T+ V+ + D +P K V T G ++ + + G PFP V W +D A
Sbjct: 18189 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 18245
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
+ ++ D L K + G+Y + N G
Sbjct: 18246 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 18283
Score = 40.4 bits (93), Expect = 0.016
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
VK V V G P P V+W +GT ++ EG I++ L L +DSG
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 19365
Query: 485 YSCTASNAQGQLSCSWTLQV 504
Y+ TA N+ G S + L+V
Sbjct: 19366 YTITAENSSGSKSATIKLKV 19385
Score = 40.4 bits (93), Expect = 0.016
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%)
Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
S++ G ++ +++ R+++ P F + V G+ F L+ V G P+P I WL
Sbjct: 23608 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 23661
Query: 550 NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
+ I+ + + CE A L ++DA+ D G Y A N G S V V ++
Sbjct: 23662 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 23718
Query: 606 SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633
P P P+ + G++ K
Sbjct: 23719 -----------PGPPEGPVQVTGVTSEK 23735
Score = 40.0 bits (92), Expect = 0.021
Identities = 46/201 (22%), Positives = 72/201 (35%), Gaps = 29/201 (14%)
Query: 1691 RRKWQKTGNAVRAIGRLS-----SMAMISGLSGRKSSTGS----PTSPLNAEKLESEEDV 1741
R +W K G ++ R S A++ K+ +G ++ ++ +S+ +
Sbjct: 8376 RIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTI 8435
Query: 1742 SQAFLEAVAEEKPHV--KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
A A +K V + +F + + VVE + A F K+ G P P V W K
Sbjct: 8436 KDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL 8495
Query: 1800 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE---- 1855
+ + L I D D Y C A N GE L V+ ++ E
Sbjct: 8496 NQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEG 8555
Query: 1856 --------------GEGEEEE 1862
G GEEEE
Sbjct: 8556 DLRAMLKKTPILKKGAGEEEE 8576
Score = 40.0 bits (92), Expect = 0.021
Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 21/180 (11%)
Query: 7 VASSHISKTSLSVDPSRVDSMPLTEAPA------FILPPRNLCIKEGATAKFEGRVRGYP 60
VA S +K+ +++ + P T+ A F+ P+++ + E TA F +V G P
Sbjct: 8423 VAGSDTTKSKVTIKDKPAVA-PATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDP 8481
Query: 61 EPQVTWHR-NGQPITSGGR-FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
P V W + + + GGR F+ G L I + D G Y C A N G +
Sbjct: 8482 IPNVKWTKGKWRQLNQGGRVFIHQKGDEA--KLEIRDTTKTDSGLYRCVAFNEHGEIESN 8539
Query: 119 VELTV---------EGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLG 168
V L V EG L + P++ K G+ +E ++ + K+A G
Sbjct: 8540 VNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPKEYEKYARMYG 8599
Score = 40.0 bits (92), Expect = 0.021
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)
Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
DP+ V L E P IL R IK G T + ++G P P+VTW + +
Sbjct: 17199 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 17258
Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ R +D G+ + +A H ED G Y+ N +G++ V+V++ V
Sbjct: 17259 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 17306
Score = 40.0 bits (92), Expect = 0.021
Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
VK T++ V G P PEVAW + T + R +++ A S L KA+ D
Sbjct: 18213 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 18271
Query: 483 GTYSCTASNAQGQLSCSWTLQV 504
G Y TA+N G T+ V
Sbjct: 18272 GKYVVTATNTAGSFVAYATVNV 18293
Score = 40.0 bits (92), Expect = 0.021
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)
Query: 598 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
V V+EK S +P VA P S V G + + V +SG P P + W
Sbjct: 23204 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 23263
Query: 657 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715
+G ++++ + +L I+E +D G Y N G+ + ++T+ +P
Sbjct: 23264 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 23323
Score = 40.0 bits (92), Expect = 0.021
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575
KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D +
Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
D G Y N G S V V ++ P P P+ + G++
Sbjct: 24774 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 24815
Score = 40.0 bits (92), Expect = 0.021
Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%)
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Q+ V+ +++ G P P W P +++ L +
Sbjct: 28365 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 28421
Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
D+G Y+ T N G S ++T++V + +V ++++ D +++G +
Sbjct: 28422 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 28481
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
V R +W Q C + +++ LAE
Sbjct: 28482 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 28521
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
SA V+E E P+ ++ AP L V+D S+ + +
Sbjct: 28522 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 28565
Query: 654 VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700
WL H+G Q+ DF E T Q + ++ + + + +A N
Sbjct: 28566 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 28623
Query: 701 AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
AG + + ++EP + T + +T G I I+G P P V W
Sbjct: 28624 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 28683
Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
+ L K+T + +D TL +K +G+Y + L+N G + V++++
Sbjct: 28684 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 28742
Query: 817 RAL-PRGREPASCED-LCGGGVGADGGGSD 844
P S E + G DGGG++
Sbjct: 28743 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 28772
Score = 39.7 bits (91), Expect = 0.028
Identities = 71/346 (20%), Positives = 136/346 (39%), Gaps = 57/346 (16%)
Query: 869 VRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRAN 928
++ + K++V + E +VE + G+K K L E K P E++ ++
Sbjct: 10900 LKAIPKKKVPEKPQVPE-----KVELTPLKVPGGEKKVRKLLPER--KPEPKEEVVLKSV 10952
Query: 929 LQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTSKTPVPEKVPPP 974
L++ + +PK ++ KV P ++V+ +V ++ K P P KVP
Sbjct: 10953 LRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--RKIPEPTKVPEI 11010
Query: 975 KPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAET 1034
KPA P LPA E A+ P +P+ PV P
Sbjct: 11011 KPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIAAPV--TVPVVG 11054
Query: 1035 LKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQ 1094
K A E KP G P + + + ++ + + G + + +
Sbjct: 11055 KKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLK 11111
Query: 1095 GTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKTLKTT---KFII 1145
F ++++D+ + E G + +C VS P+T I W +G ++ + +FI
Sbjct: 11112 AVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSNIRESPKHRFIA 11168
Query: 1146 LSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
++ L + ++ + D G Y CV + + + ++ V++ P
Sbjct: 11169 DGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 11211
Score = 39.7 bits (91), Expect = 0.028
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 1737 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 11991 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 12049
Query: 1791 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 12050 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 12089
Score = 39.7 bits (91), Expect = 0.028
Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)
Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
PSR + ++ EAP L + L +K G + V G PEP++TW + +
Sbjct: 13672 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 13731
Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
R ++ + ++ I D G Y EA N G VE+ V
Sbjct: 13732 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 13780
Score = 39.7 bits (91), Expect = 0.028
Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V E + + +P P V+W +G V+ + + + D S +L + K+ D+G
Sbjct: 14398 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 14456
Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
Y+ T N G + S ++V + + ++ S + + +G +L +
Sbjct: 14457 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 14516
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
R T++ P+ + V +D +P + A N +G
Sbjct: 14517 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 14560
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
E PV P P D++V + + MT+ + PP L
Sbjct: 14561 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 14604
Query: 658 HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712
++G +G + C + + P TYT + E VR + +
Sbjct: 14605 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 14662
Query: 713 QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
EP T P P S+ G + + +I+G P+PT+ W++D
Sbjct: 14663 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 14716
Score = 39.7 bits (91), Expect = 0.028
Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L I+ G GR G P+P+V+W ++ + R + T +L D
Sbjct: 16828 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 16886
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
GKY N +G+R+ ++ V + G PV + F + W
Sbjct: 16887 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 16938
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221
+K+ ++++ ++G+ V + + + +VS + + IH
Sbjct: 16939 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 16987
Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273
N G+ LV + SM A+ + D+ ++ V E ++ D K
Sbjct: 16988 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 17040
Query: 274 EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317
+TN I ++ + S A +K+ C R + P PP
Sbjct: 17041 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 17100
Query: 318 RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373
+ +K K SP P+ S +T Q R + G V G+E R
Sbjct: 17101 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 17160
Query: 374 PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420
A P + P T+ G +D K + G+ D A K +P
Sbjct: 17161 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 17220
Query: 421 -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
+ Q +K T++ + G+P P+V W E + I+V GS L +
Sbjct: 17221 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 17277
Query: 476 KARTRDSGTYSCTASNAQGQLSCS 499
A D G YS T N G + S
Sbjct: 17278 NAAHEDGGIYSLTVENPAGSKTVS 17301
Score = 39.7 bits (91), Expect = 0.028
Identities = 23/81 (28%), Positives = 34/81 (41%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VVK G RF I G P P W ++ +V N VL I + D G
Sbjct: 17520 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 17579
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y V N +G +++ L++
Sbjct: 17580 EYQITVSNAAGSKTVAVHLTV 17600
Score = 39.7 bits (91), Expect = 0.028
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
+++ A + + + P V EAP L + + ++ G +A+ +G P
Sbjct: 23993 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 24052
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P++TW R T + ++ G+ T L I D GKY + N SG++ V
Sbjct: 24053 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 24109
Query: 121 LTV 123
+ V
Sbjct: 24110 VKV 24112
Score = 39.7 bits (91), Expect = 0.028
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V + G L L VS PP I W+ G L + I ++ SL + ++K D G
Sbjct: 29456 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 29513
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191
Y A+N +G+ + V V D P
Sbjct: 29514 KYTIEAENQSGKKSATVLVKVYDTP 29538
Score = 39.3 bits (90), Expect = 0.036
Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779
P F +SV G + I+G P P V W RDG+ + T ++ ++ L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839
+ V ++G+Y + N G+ + L+++ +A P + L +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116
Query: 840 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893
G R G P + DG +++ L ++ E
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 894 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953
++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D
Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231
Query: 954 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005
RS+ + G + +P K PP P P RS + K +L + S
Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287
Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032
S P+ + + P PV + PA
Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310
Score = 39.3 bits (90), Expect = 0.036
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 14376 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 14435
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
D + L + D YT N LG AT + + V
Sbjct: 14436 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 14476
Score = 39.3 bits (90), Expect = 0.036
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)
Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575
SV ++ G+ + V G PVP W + R + +EL I+DAL
Sbjct: 15109 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 15168
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
+DHG Y A N+ G +A V V + +L + P + L SD +
Sbjct: 15169 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 15223
Query: 636 DGSQVT 641
GS++T
Sbjct: 15224 GGSEIT 15229
Score = 39.3 bits (90), Expect = 0.036
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785
G + I I G P P W DGKA KD H E +N V +++ + +
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 15882
Query: 786 PWHAGQYEILLKNRVGE--CSCQVSLM 810
H G+Y I KN+ G+ +C+V +M
Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVM 15909
Score = 39.3 bits (90), Expect = 0.036
Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 668 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
D HFE G H + + G ++ E S G + + V P P +
Sbjct: 22495 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 22551
Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
++ G+S + I G P PT+ W++ + L +T E+ + +L +K
Sbjct: 22552 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 22607
Query: 786 PWHAGQYEILLKNRVGECSCQVSL 809
+G Y + KN GE S V++
Sbjct: 22608 RVDSGNYILKAKNVAGERSVTVNV 22631
Score = 38.9 bits (89), Expect = 0.047
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
++V +G A K G + WFKD Q + ++I + + IIS D
Sbjct: 4588 IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTE-KKDS 4646
Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
+YT + N +G ++C A + V
Sbjct: 4647 GEYTFEVQNDVGRSSCKARINV 4668
Score = 38.9 bits (89), Expect = 0.047
Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 1/81 (1%)
Query: 1768 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
+ + S F ++G P ++ WFKDD + I E L + V
Sbjct: 5340 QAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGL-EGSTSFLNLYSVDASKTG 5398
Query: 1828 KYTCKAVNSLGEATCTAELIV 1848
+YTC N +G +CT L+V
Sbjct: 5399 QYTCHVTNDVGSDSCTTMLLV 5419
Score = 38.9 bits (89), Expect = 0.047
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ V G + + +V G P P++ W G + + Q + L I+E D G
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977
Query: 692 TYTCEAWNSAGEVRTQAVLTV 712
Y A NS+G + A++ V
Sbjct: 17978 KYIISAKNSSGHAQGSAIVNV 17998
Score = 38.9 bits (89), Expect = 0.047
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
SV A G+ V + G P PTV W +D K L D + + + L + +V
Sbjct: 27280 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 27338
Query: 789 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
G+Y + ++N VGE SS ++ PA+C+ L
Sbjct: 27339 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 27372
Score = 38.9 bits (89), Expect = 0.047
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584
G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT +
Sbjct: 27578 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 27637
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
+NA+ +++ V L P PSKP PI
Sbjct: 27638 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 27664
Score = 38.5 bits (88), Expect = 0.062
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
G E+ T + PAP P PP ++ ++ V GESV L ++G T TW +
Sbjct: 921 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 978
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
QI+ S ++ ++L I A E G +T N+ G+ L V
Sbjct: 979 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 38.5 bits (88), Expect = 0.062
Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 614 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
PV ++P P + + +++M G + + V+G P P +W E+ + +
Sbjct: 15092 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 15150
Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
+ GT+ L I++ +D G Y A NS G
Sbjct: 15151 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 15183
Score = 38.5 bits (88), Expect = 0.062
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
L +K G T + E VRG P P+V W ++ +T R +D + FSL
Sbjct: 18211 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 18268
Query: 99 EDRGKYTCEATNGSGA 114
D GKY ATN +G+
Sbjct: 18269 SDGGKYVVTATNTAGS 18284
Score = 38.5 bits (88), Expect = 0.062
Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%)
Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
IP EG+ D+ K + ++ T++ V G P P++ W +R + G ++
Sbjct: 19689 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 19741
Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515
+ +L D+G Y T N+ G+ + ++V + V E++
Sbjct: 19742 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 19801
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+ V + +I+G ++ V+ R +W + T E + +
Sbjct: 19802 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 19852
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
+ AEN G + + +R + V S+ P+ DLKV
Sbjct: 19853 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 19893
Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691
S+ + ++ G P G+ I DF E+ Q SL +Q + T
Sbjct: 19894 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 19947
Query: 692 ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744
T+ A N GE T + +TV D P K A + + I
Sbjct: 19948 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 20006
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
G P P+V W + L DT V + TL++ Q AG+Y I LKN G
Sbjct: 20007 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065
Query: 805 CQVSL 809
+S+
Sbjct: 20066 GTISI 20070
Score = 38.5 bits (88), Expect = 0.062
Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
PAF L + G K + G P P VTWH++ P+ R + L
Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 22206
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I ED G Y + TN +G T+ + V G + + D +
Sbjct: 22207 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 22261
Query: 153 PSIWGECPPKF 163
WG PPK+
Sbjct: 22262 ---WG--PPKY 22267
Score = 38.5 bits (88), Expect = 0.062
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 23632 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 23690
Query: 1824 DDDAKYTCKAVNSLG 1838
D +Y +A N G
Sbjct: 23691 IDGGQYILRASNVAG 23705
Score = 38.5 bits (88), Expect = 0.062
Identities = 22/83 (26%), Positives = 37/83 (44%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ K G I+GRP P+VTW + L+ + RVS++ L + + D G
Sbjct: 28657 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 28716
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y + N +G + S + + G
Sbjct: 28717 RYFLTLENTAGVKTFSVTVVVIG 28739
Score = 38.1 bits (87), Expect = 0.081
Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)
Query: 541 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
PV W+ +N +PI+ + E GV +P+ A NA+G
Sbjct: 14325 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 14368
Query: 600 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
+ S SE ++ P KPT + D+ V++G ++++ V P P V W
Sbjct: 14369 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 14422
Query: 659 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717
+G E++ S+ + L + + D G YT N G V + P
Sbjct: 14423 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 14480
Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771
P K +T S SC + +P P +H++ + + + T + V+
Sbjct: 14481 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 14530
Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
E+ + +K + P + + N+VG
Sbjct: 14531 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 14560
Score = 37.7 bits (86), Expect = 0.11
Identities = 51/198 (25%), Positives = 74/198 (37%), Gaps = 45/198 (22%)
Query: 47 GATAKFEGRVRGYPEPQVT-WHRNGQPITSGG--RFLLDCGIRGTFSLVIHAVHEEDRGK 103
G++A FE V P +T W ++G I RF+ D R L I V D G+
Sbjct: 11133 GSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDR---KLHIIDVQLSDAGE 11187
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
YTC G+ + T +L VE E P +F
Sbjct: 11188 YTCVLRLGNKEKTSTAKLVVE---------------------------------ELPVRF 11214
Query: 164 ATKLGR-VVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEIH 221
L V V +GQ SC++ + V W K G + ++ R+ M+ L I+
Sbjct: 11215 VKTLEEEVTVVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTIN 11272
Query: 222 GVNQDDVGVYTCLVVNGS 239
+ D G YT V N +
Sbjct: 11273 DADDTDAGTYTVTVENAN 11290
Score = 37.7 bits (86), Expect = 0.11
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
Query: 620 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672
PT + L D +KV G V + V+G P P++ W N I++ D
Sbjct: 15395 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 15454
Query: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
+ + L I + ED GTYT A N G V
Sbjct: 15455 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 15486
Score = 37.7 bits (86), Expect = 0.11
Identities = 20/73 (27%), Positives = 33/73 (45%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V++K G+ R ++GRP P + W K L+ +A++ + + L + D G
Sbjct: 21471 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 21530
Query: 230 VYTCLVVNGSGKA 242
YT N G A
Sbjct: 21531 AYTLTATNPGGFA 21543
Score = 37.7 bits (86), Expect = 0.11
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
+AP L P+ + + G T E +RG P P V W ++G+ + + R + I+
Sbjct: 24703 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 24762
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
T +LV+ D G+Y + +N G + + + + V
Sbjct: 24763 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 24798
Score = 37.7 bits (86), Expect = 0.11
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)
Query: 617 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663
PS+ T PI ++ + D+K D G + + ++G P P + W +G EI
Sbjct: 25771 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 25830
Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
+E L +++ DTG Y N AG
Sbjct: 25831 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 25869
Score = 37.7 bits (86), Expect = 0.11
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
+ G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y
Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 28029
Query: 1169 KCVAKNDAGQAECSCQVTVDDAP 1191
AKN +G A+ +V V D P
Sbjct: 28030 TVEAKNASGSAKAEIKVKVQDTP 28052
Score = 37.4 bits (85), Expect = 0.14
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1825
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 15170
Query: 1826 DAKYTCKAVNSLGEATCTAELIV 1848
+Y A NS G A + V
Sbjct: 15171 HGRYVITATNSCGSKFAAARVEV 15193
Score = 37.4 bits (85), Expect = 0.14
Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 17976
Query: 790 GQYEILLKNRVG 801
G+Y I KN G
Sbjct: 17977 GKYIISAKNSSG 17988
Score = 37.4 bits (85), Expect = 0.14
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584
G + L +V G P+P ++W +G +P + + + + L + +D G YT
Sbjct: 19310 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 19369
Query: 585 AENALGQVSCSAWVTVHEK 603
AEN+ G S + + V +K
Sbjct: 19370 AENSSGSKSATIKLKVLDK 19388
Score = 37.4 bits (85), Expect = 0.14
Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
VDP R+ P + + + G + K + + G P P + W + Q +++ R
Sbjct: 22538 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 22589
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ T SL + D G Y +A N +G R VTV + V G V+S
Sbjct: 22590 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 22648
Query: 139 TLGDR 143
++
Sbjct: 22649 VTAEK 22653
Score = 37.4 bits (85), Expect = 0.14
Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480
V+ + + G P PE+ W R+EG +V + G +Y L +
Sbjct: 24036 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 24088
Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
D+G Y N+ G S T++V + LAV EV + ++ + +I+G V
Sbjct: 24089 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 24148
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
+ R YA + + +++ + +AEN G
Sbjct: 24149 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 24196
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
V V + + +E P P K T + D SQ + ++ PE
Sbjct: 24197 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 24237
Query: 654 VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703
H+G + +GT+ +C V +G + +A+N G+
Sbjct: 24238 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 24293
Query: 704 VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
+ + D T QP + + G+ + I + G P P + W++DG+ L
Sbjct: 24294 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 24352
Query: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
K T V + L +K+ G+Y + N G + +S+++
Sbjct: 24353 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401
Score = 37.4 bits (85), Expect = 0.14
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 1740 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 26167 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 26225
Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 26226 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 26276
Score = 37.4 bits (85), Expect = 0.14
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ +
Sbjct: 26482 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 26540
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
D G+Y A N SG + + + V G V+S
Sbjct: 26541 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 26580
Score = 37.4 bits (85), Expect = 0.14
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y +
Sbjct: 27973 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 28031
Query: 795 LLKNRVGECSCQVSLMLQNSSARAL 819
KN G ++ + +Q++ + +
Sbjct: 28032 EAKNASGSAKAEIKVKVQDTPGKVV 28056
Score = 37.0 bits (84), Expect = 0.18
Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)
Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137
+ H G + + P + V V EG+ +C+V+ P + W LNG+
Sbjct: 1821 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1880
Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195
++ +K + +G + + I D G K A+N G E ++ + S
Sbjct: 1881 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1939
Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
+APE RP+ + + + +P T K + + + +KV ES
Sbjct: 1940 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1995
Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290
EL K + IT +K RK+ + E + K +E
Sbjct: 1996 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2055
Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340
G K+TI L+ E + + +G A + VV KPDP
Sbjct: 2056 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2109
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400
WY + IE D W E C ++D+ +
Sbjct: 2110 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2147
Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451
V+AIN+ G + Q +L T ++ ++ KD + + + EP V +
Sbjct: 2148 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2207
Query: 1452 VTINTEQKVSDFY 1464
E D Y
Sbjct: 2208 YKDGMEVHEGDKY 2220
Score = 37.0 bits (84), Expect = 0.18
Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%)
Query: 935 PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994
P+ V E + K+ Q+ DFRSVL + P P+ P+F GK + +
Sbjct: 1917 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1962
Query: 995 NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054
+T K V K + + K E + + + T + A
Sbjct: 1963 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 2013
Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101
LKS K+E +++ + H T+ EK++ E + T P FK
Sbjct: 2014 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2073
Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152
+++Q V +G + +V P W NG K ++ + E ++
Sbjct: 2074 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2133
Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178
C + I ED A N AG+
Sbjct: 2134 CELVIRDVTAEDSASIMVKAINIAGE 2159
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + VSG PPP V W N NE ++ E S+ I+ G Y+
Sbjct: 16539 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 16596
Query: 697 AWNSAGEVRTQAVLTV 712
A N AGE + ++ V
Sbjct: 16597 AKNEAGERKKTIIVDV 16612
Score = 37.0 bits (84), Expect = 0.18
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 1763 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1819
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 17913 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 17969
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTA 1844
+ D KY A NS G A +A
Sbjct: 17970 EAVRADHGKYIISAKNSSGHAQGSA 17994
Score = 37.0 bits (84), Expect = 0.18
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 1749 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1802
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 18187 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 18246
Query: 1803 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
++ D + S ++ D KY A N+ G A + V
Sbjct: 18247 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293
Score = 37.0 bits (84), Expect = 0.18
Identities = 22/92 (23%), Positives = 40/92 (43%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + G ++ + V G P P W +E+ S + + L I++V +D+G
Sbjct: 18908 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 18967
Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723
Y+ A NS+G + + V + QP F
Sbjct: 18968 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 18999
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 23008
Query: 1827 AKYTCKAVNSLG 1838
KYT NS G
Sbjct: 23009 GKYTLTLENSSG 23020
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 1758 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 26928
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
S++I D + Y K N++G A+ T
Sbjct: 26929 SILIKDADRLNSGCYELKLRNAMGSASAT 26957
Score = 37.0 bits (84), Expect = 0.18
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V + G + I+G+P P + W K + LQ +A V V + + I ++ + G
Sbjct: 26882 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 26941
Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254
Y + N G A SA + +Q LD
Sbjct: 26942 CYELKLRNAMGSA--SATIRVQILD 26964
Score = 36.6 bits (83), Expect = 0.23
Identities = 17/77 (22%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
++P + + ++D+ + EG C+ P+ + WF++ + ++ + + + +
Sbjct: 8743 IEPAWERHLQDVTLKEGQTCTMTCQFS-VPNVKSEWFRNGRILKPQGRHKTEVEHKVH-K 8800
Query: 1816 LIISDVCGDDDAKYTCK 1832
L I+DV +D +YTCK
Sbjct: 8801 LTIADVRAEDQGQYTCK 8817
Score = 36.6 bits (83), Expect = 0.23
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)
Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
RF A E R + PK T +VV G+ P+ + W K N PL
Sbjct: 12982 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 13041
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ +E+ ++LE + D G Y ++ N GKA L +
Sbjct: 13042 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 13086
Score = 36.6 bits (83), Expect = 0.23
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
V+EG KI G P P +TW K P +P + V + N + V L I
Sbjct: 16128 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 16186
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
+ D G+YT VN G AS L++ G
Sbjct: 16187 RRSDTGLYTITAVNNLGTASKEMRLNVLG 16215
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586
G L ++G P P++TW + AR ++L I++A ED G Y+ E
Sbjct: 17233 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 17292
Query: 587 NALGQVSCSAWVTVHEK 603
N G + S V V +K
Sbjct: 17293 NPAGSKTVSVKVLVLDK 17309
Score = 36.6 bits (83), Expect = 0.23
Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643
A+N G +S + T + K EY P PT L + G + +
Sbjct: 20350 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 20400
Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
+ + G P P+ W G +I+ S+ T L I+ +D G YT A N G
Sbjct: 20401 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 20460
Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
+TV + P IS + A+L
Sbjct: 20461 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 20491
Score = 36.6 bits (83), Expect = 0.23
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y
Sbjct: 26488 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 26547
Query: 694 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725
A NS+G + ++ + P T P IS
Sbjct: 26548 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 26580
Score = 36.6 bits (83), Expect = 0.23
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 1743 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 28631 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 28689
Query: 1800 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 28690 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 28737
Score = 36.2 bits (82), Expect = 0.31
Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F K + D + +G + G P V W K+ ++ S+ I E + L I
Sbjct: 7870 FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK-SAILEIP 7928
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+D +Y C N+ G+ +C+A++++
Sbjct: 7929 SSTVEDAGQYNCYIENASGKDSCSAQILI 7957
Score = 36.2 bits (82), Expect = 0.31
Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 1076 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128
NC+ G D N K S P + L+DV V G+ C++S +
Sbjct: 12167 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 12225
Query: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
+ W L GK L+ + ++ EG + ++++ ED G + AK+
Sbjct: 12226 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 12271
Score = 36.2 bits (82), Expect = 0.31
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%)
Query: 438 SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
SG PKP+V+WF + V ++ + + L +KA+ DSG Y N+ G
Sbjct: 16843 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 16901
Query: 498 CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
+ V V P SF V KD VI
Sbjct: 16902 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 16931
Score = 36.2 bits (82), Expect = 0.31
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
++ + G++ + + G P PT+ WLR K + +++ E+ + L++K
Sbjct: 23634 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 23692
Query: 789 AGQYEILLKNRVGECSCQVSL 809
GQY + N G S V++
Sbjct: 23693 GGQYILRASNVAGSKSFPVNV 23713
Score = 35.8 bits (81), Expect = 0.40
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1816
P F + L VV G A IEG V W K+ ++ IRES + +I + E+ +L
Sbjct: 5610 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVEN-VATL 5668
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+ + KY C+ N G A L+V
Sbjct: 5669 QFAKAEPANAGKYICQIKNDGGMRENMATLMV 5700
Score = 35.8 bits (81), Expect = 0.40
Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDD 1825
+ V G+ +C + G P+ WFKD + + +S+H ++ + + +++ D
Sbjct: 6654 MTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEM--SD 6711
Query: 1826 DAKYTCKAVNSLGEATCTAELIV 1848
Y+ + NS+G++ CT + V
Sbjct: 6712 KGLYSFEVKNSVGKSNCTVSVHV 6734
Score = 35.8 bits (81), Expect = 0.40
Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
T S ++ + E ++ +A N G + ++ L V + D P
Sbjct: 15351 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 15395
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
++ R S+ G+ + VK G+ +TG P P++ W K ++
Sbjct: 15396 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 15445
Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
+ VS L I ++D G YT N G + + + S R+
Sbjct: 15446 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 15505
Query: 261 VRETKA 266
V + KA
Sbjct: 15506 VTDIKA 15511
Score = 35.8 bits (81), Expect = 0.40
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G +V I G P PT W DG + K H+ V + L +K G+Y+I
Sbjct: 17525 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 17583
Query: 795 LLKNRVGECSCQVSL 809
+ N G + V L
Sbjct: 17584 TVSNAAGSKTVAVHL 17598
Score = 35.8 bits (81), Expect = 0.40
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
EAP +L P L IK G T + G P P+ +W + G+ I +
Sbjct: 20374 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 20433
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ + +A + D G+YT ATN G + V++TV
Sbjct: 20434 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 20469
Score = 35.8 bits (81), Expect = 0.40
Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584
G + ++ V G P P +TW Q ++ + A L+I + + D G Y
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 21139
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
A N +G+V + VH+ P PT PI
Sbjct: 21140 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 21166
Score = 35.8 bits (81), Expect = 0.40
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 23010
Query: 104 YTCEATNGSGARQVTVELTV 123
YT N SG + V + V
Sbjct: 23011 YTLTLENSSGTKSAFVTVRV 23030
Score = 35.8 bits (81), Expect = 0.40
Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P+ LP +K K + +G P+ V W ++GQ + R + T SL
Sbjct: 25395 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-SLS 25453
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I +ED G Y +N +G+ +TV +T+
Sbjct: 25454 IKEASKEDVGTYELCVSNSAGS--ITVPITI 25482
Score = 35.8 bits (81), Expect = 0.40
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 1782 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 27296 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 27352
Score = 35.8 bits (81), Expect = 0.40
Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)
Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142
+T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + +
Sbjct: 33315 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 33374
Query: 1143 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ L ++ I +D GLY N+ G + + +
Sbjct: 33375 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 35.4 bits (80), Expect = 0.52
Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F + L ++ V+E + L C+VS P A +IW + + T + EG + I+
Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 12523
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
A ED G Y C R P S +D
Sbjct: 12524 AHLEDAGNYNC---------------------------------RLPSS--------RTD 12542
Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
VK + + I P++ ++ GE E ++ + W + K ++
Sbjct: 12543 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 12592
Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
+ V L + A + G Y ++V G+ +A +LTV++K
Sbjct: 12593 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 12639
Score = 35.4 bits (80), Expect = 0.52
Identities = 16/82 (19%), Positives = 37/82 (45%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
++ ++ G+ + + +G+P+P+V+W K + R + LE + D
Sbjct: 16827 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 16886
Query: 229 GVYTCLVVNGSGKASMSAELSI 250
G Y +V N +G ++++
Sbjct: 16887 GKYCVVVENSTGSRKGFCQVNV 16908
Score = 35.4 bits (80), Expect = 0.52
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)
Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676
KP + L G+ L V G + + V G P PEV W + ++ S + R
Sbjct: 18200 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 18257
Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+ + D G Y A N+AG A + V
Sbjct: 18258 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293
Score = 35.4 bits (80), Expect = 0.52
Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)
Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
+ +A+NA G +S + T + K E LP P + + V G
Sbjct: 23593 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 23643
Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
+ V G P P + WL EI+ES + + L +++ D G Y A N
Sbjct: 23644 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 23703
Query: 701 AG 702
AG
Sbjct: 23704 AG 23705
Score = 35.4 bits (80), Expect = 0.52
Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ +K G K + G P P ++W ++G I R + T L + D
Sbjct: 25799 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 25857
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
G+Y N +G R V V V G ++ ++ S P + I
Sbjct: 25858 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 25917
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205
K T + EG++ SCK+T LKGN + +P
Sbjct: 25918 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 25970
Query: 206 RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
V++ + V LEI V ++ + + C S S + I+ + +
Sbjct: 25971 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 26028
Query: 260 FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314
+VR K D+R + T + E ++ + AA S S R P + P
Sbjct: 26029 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 26084
Query: 315 QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373
PP + K+ +S K + A P+ + + + + S G E
Sbjct: 26085 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 26144
Query: 374 PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
A + R +G+ D S +++ +I E + + F ++ VK +
Sbjct: 26145 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 26203
Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
G P P V W T +R + ++ + S L + A DSG Y+ T
Sbjct: 26204 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 26260
Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526
N S + ++V + V K+ AV+
Sbjct: 26261 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 26296
Score = 35.4 bits (80), Expect = 0.52
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V++G + R + I G+P P W K + A ++ SE + L I ++ D G
Sbjct: 30146 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 30203
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y ++ N GK ++ ++ + G
Sbjct: 30204 TYDLVLENKCGKKAVYIKVRVIG 30226
Score = 35.4 bits (80), Expect = 0.52
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1816
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 32374 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 32431
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
I D DD Y N GEA+ A L V
Sbjct: 32432 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463
Score = 35.0 bits (79), Expect = 0.68
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 11842 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 11899
Query: 1820 DVCGDDDAKYTCKA 1833
+D+AKY +A
Sbjct: 11900 SAAFEDEAKYMFEA 11913
Score = 35.0 bits (79), Expect = 0.68
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
R+VV G + R ++G+P P VTW L A + + + V I +
Sbjct: 16533 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 16590
Query: 229 GVYTCLVVNGSGK 241
GVY+ L N +G+
Sbjct: 16591 GVYSLLAKNEAGE 16603
Score = 35.0 bits (79), Expect = 0.68
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
++ G + VRG P P+VTW + G + G L+D LVI +D
Sbjct: 18618 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 18673
Query: 102 GKYTCEATNGSGARQVTVELTV 123
GKY+ N +G + V V + V
Sbjct: 18674 GKYSLTLVNPAGEKAVFVNVRV 18695
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 19363
Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
YT A NS G + T +L V
Sbjct: 19364 GDYTITAENSSGSKSATIKLKV 19385
Score = 35.0 bits (79), Expect = 0.68
Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 615 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
VA AP + L+GL DL + + S + + + G P P V W + +
Sbjct: 19972 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 20031
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721
E +L + + D G YT N AG + T ++ V +P T P
Sbjct: 20032 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 20082
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
D + AP + P+I K G +V + I G+P P+ +W K +
Sbjct: 20371 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 20420
Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
+PS ++ +L I + D G YT N G
Sbjct: 20421 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 20459
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
+V G ++ + I+G P P V RDG L K T F + T+ LK+
Sbjct: 26485 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 26543
Query: 789 AGQYEILLKNRVGECSCQVSLML 811
AG+YEI N G +++++
Sbjct: 26544 AGRYEITAANSSGTTKAFINIVV 26566
Score = 35.0 bits (79), Expect = 0.68
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565
V+++ ++ V+K A G L+ + G P P I W + + +Q C +
Sbjct: 26871 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 26927
Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
A + I+DA + G Y NA+G S + V + +K
Sbjct: 26928 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 26965
Score = 34.7 bits (78), Expect = 0.89
Identities = 18/82 (21%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
++V G A + + G P+ + W+KD + + S+ ++I + ++ L D
Sbjct: 4026 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDS 4084
Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
+YT + N +G ++C V
Sbjct: 4085 GQYTFEISNEVGSSSCETTFTV 4106
Score = 34.7 bits (78), Expect = 0.89
Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%)
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
V P+ W G PV + + E+ G Y Y A N QG
Sbjct: 13624 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 13670
Query: 497 SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553
S T +++ + E F V L V G L +V G P P+ITW
Sbjct: 13671 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 13730
Query: 554 I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
+ Q R T E + + I D+ D GTY A N G+ + V V +K
Sbjct: 13731 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 13783
Score = 34.7 bits (78), Expect = 0.89
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + G P P + W+ E+ + + SL +++ D+G Y +
Sbjct: 22558 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 22617
Query: 697 AWNSAGE 703
A N AGE
Sbjct: 22618 AKNVAGE 22624
Score = 34.7 bits (78), Expect = 0.89
Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%)
Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451
+SK ++ P+ + + P+ P+ ++ V +T + +V G P P + W L G
Sbjct: 23604 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 23662
Query: 452 TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
+ E+ L + A D G Y ASN G S
Sbjct: 23663 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 23708
Score = 34.7 bits (78), Expect = 0.89
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ AT + ++G PEP+V W + +T + + +F+ LVI V D G
Sbjct: 25119 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 25174
Query: 103 KYTCEATNGSGARQVTVELTV 123
+Y N SG++ V + V
Sbjct: 25175 RYNLTLENNSGSKTAFVNVRV 25195
Score = 34.7 bits (78), Expect = 0.89
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 25393 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 25451
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I + +D Y NS G T +IV
Sbjct: 25452 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 25484
Score = 34.3 bits (77), Expect = 1.2
Identities = 47/193 (24%), Positives = 71/193 (36%), Gaps = 18/193 (9%)
Query: 1666 PWLMKDTKNMEAKKLSKDRMKKYMA-----RRKWQKTGNAVRAIGRLSSMAMISGLSG-- 1718
P+ K +N+++ R+ +A R W K G + A R +A + G +
Sbjct: 4113 PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYR-IAFVEGTASLE 4171
Query: 1719 --RKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAAR 1776
R + A +D S A + V E V SK +V+ GSA
Sbjct: 4172 IIRVDMNDAGNFTCRATNSVGSKDSSGALI--VQEPPSFVTKPGSK-----DVLPGSAVC 4224
Query: 1777 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 1836
+G + WFK ++ + I E SL + V D YTCK N
Sbjct: 4225 LKSTFQGSTPLTIRWFKGNKELVSGGSCYIT-KEALESSLELYLVKTSDSGTYTCKVSNV 4283
Query: 1837 LGEATCTAELIVE 1849
G C+A L V+
Sbjct: 4284 AGGVECSANLFVK 4296
Score = 34.3 bits (77), Expect = 1.2
Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Query: 1720 KSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKT-IRDLE---VVEGSAA 1775
K S T L E++E E + F E V+ + + T I+D+E V++ + A
Sbjct: 8614 KQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDA 8673
Query: 1776 RFDCKIE-GYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
F+ I+ YP+ ++ W+K + + S F+I D D
Sbjct: 8674 VFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGD 8710
Score = 34.3 bits (77), Expect = 1.2
Identities = 45/214 (21%), Positives = 87/214 (40%), Gaps = 40/214 (18%)
Query: 879 TRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLK-EIPA----------EQMDFRA 927
+R+ EE ++ +V ++ + ++ +K S + E+ ++ ++PA E+M F +
Sbjct: 9193 SRRMEEEKVQVTKVPEVS-KKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFAS 9251
Query: 928 NLQRQVK---PKTVSE--EERKVH---------SPQQVDFRSVLAKKGTSKTPVPEKVPP 973
+ + +V P+ E E K+H P+ + A + + P+P+KV P
Sbjct: 9252 HTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEP 9311
Query: 974 PKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQ-PSGPLKPVGNAKPA 1032
P P P+ KK +P E V +P + + P P KPV K
Sbjct: 9312 PAPKVPEV-----PKKPVPEEK--------KPVPVPKKEPAAPPKVPEVPKKPVPEEKIP 9358
Query: 1033 ETLKPMGNAKPAETLKPMGNAKPDENLKSASKEE 1066
+ A PA+ + +E + ++ E
Sbjct: 9359 VPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQRE 9392
Score = 34.3 bits (77), Expect = 1.2
Identities = 35/139 (25%), Positives = 57/139 (41%), Gaps = 25/139 (17%)
Query: 136 VSKTLGDRFSAPAVETRPSIWGECPP--------------KFATKLGRVVVKE----GQM 177
V K A + RP GE PP KF ++ +++ E G
Sbjct: 11076 VPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSS 11135
Query: 178 GRFSCKITGRPQPQVT-WLK--GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
F C ++ P +T W+K N+ P R K+ + L I V D G YTC+
Sbjct: 11136 AIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKD--RKLHIIDVQLSDAGEYTCV 11191
Query: 235 VVNGSGKASMSAELSIQGL 253
+ G+ + + +A+L ++ L
Sbjct: 11192 LRLGNKEKTSTAKLVVEEL 11210
Score = 34.3 bits (77), Expect = 1.2
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 12646 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 12703
Query: 1824 DDDAKYTCKAVNSLGE-ATCTAELIVE 1849
DD A Y N GE A LIVE
Sbjct: 12704 DDQANYNVSLTNHRGENVKSAANLIVE 12730
Score = 34.3 bits (77), Expect = 1.2
Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%)
Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470
+A PK ++ Q V + + PK E WF E P+ + +I+ + S
Sbjct: 12997 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 13053
Query: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523
+L+A+ D G Y N G+ L+ V L V E S+ +
Sbjct: 13054 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 13112
Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLL 549
+ +G ++ V + R TW+L
Sbjct: 13113 PLTDGGSKIIGYVVERRDIKRKTWVL 13138
Score = 34.3 bits (77), Expect = 1.2
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
G+ L S +K +S DPS + PLT AF+ P +L K+G +
Sbjct: 13359 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 13416
Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
GYP P TW + + +G R + + LVI D+G YT + N
Sbjct: 13417 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 13471
Score = 34.3 bits (77), Expect = 1.2
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
G + VK G R + G+P P+V W K L S RV + + + +
Sbjct: 18209 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 18268
Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250
D G Y N +G A +++
Sbjct: 18269 SDGGKYVVTATNTAGSFVAYATVNV 18293
Score = 34.3 bits (77), Expect = 1.2
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 1761 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 24028 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 24083
Query: 1821 VCGDDDA-KYTCKAVNSLG 1838
C +DA KY K NS G
Sbjct: 24084 NCDRNDAGKYILKLENSSG 24102
Score = 34.3 bits (77), Expect = 1.2
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
P V + E P + L R + +++G + ++G P P W + GQ I+
Sbjct: 30122 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 30179
Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
R ++ T LVI D G Y N G + V +++ V GS
Sbjct: 30180 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 30227
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+ G + I ++G P PTV W + + L ++ + ++V+K Q H
Sbjct: 16534 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 16590
Query: 790 GQYEILLKNRVGE 802
G Y +L KN GE
Sbjct: 16591 GVYSLLAKNEAGE 16603
Score = 33.9 bits (76), Expect = 1.5
Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%)
Query: 537 VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
+RG PVP W +G I ++ + + L I++ L D G Y NA G +
Sbjct: 17534 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 17593
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
+ +TV + P PT PI ++D + MT +S PP +
Sbjct: 17594 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 17630
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 21534
Query: 1832 KAVNSLGEA 1840
A N G A
Sbjct: 21535 TATNPGGFA 21543
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)
Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
+P+ V P E +LPP + + I+ T + ++G P P+V W R+
Sbjct: 21841 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 21898
Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
G L I T S L++ V+ D GKY N SG++ V + V
Sbjct: 21899 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 21948
Score = 33.9 bits (76), Expect = 1.5
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + G + + V + G P PEV W EI+++ T SL + V D+G
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 23009
Query: 692 TYTCEAWNSAG 702
YT NS+G
Sbjct: 23010 KYTLTLENSSG 23020
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
+++ P V + +T E +P + ++ G E +G P+P ++W ++G P+
Sbjct: 27547 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 27606
Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
F+ +L I +E GKYT N ++ V +TV
Sbjct: 27607 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 27651
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 1745 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1794
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 29428 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 29482
Query: 1795 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 29483 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 29529
Score = 33.5 bits (75), Expect = 2.0
Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 3/132 (2%)
Query: 916 KEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTP-VPEK-VPP 973
KE+ E++ F + V+ V EEE +H ++ + K P VP K VP
Sbjct: 9901 KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPE 9960
Query: 974 PKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAE 1033
K P + K+P E E + + KP P P KPV K
Sbjct: 9961 EKKPVPVPKKKEAPPAKVP-EVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPV 10019
Query: 1034 TLKPMGNAKPAE 1045
+ A PA+
Sbjct: 10020 PVPKKVEAPPAK 10031
Score = 33.5 bits (75), Expect = 2.0
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 11576 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 11633
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+V DD ++ + + E + TA+L V
Sbjct: 11634 EVTLDDISQIKAQ----VKELSSTAQLKV 11658
Score = 33.5 bits (75), Expect = 2.0
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 11931 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 11988
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCT 1843
D+ DD ++ +A+ EA T
Sbjct: 11989 DLSIDDTSQIRVEAMGMSSEAKLT 12012
Score = 33.5 bits (75), Expect = 2.0
Identities = 20/72 (27%), Positives = 32/72 (44%)
Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
TG P+P TW G+ L+ RV + + L I + D G+YT + N S
Sbjct: 13419 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 13478
Query: 245 SAELSIQGLDSA 256
++++ SA
Sbjct: 13479 EIDVNVIARPSA 13490
Score = 33.5 bits (75), Expect = 2.0
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)
Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
S IS+ ++ DP P L ++ + EG R P P V+WH++
Sbjct: 14372 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 14423
Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
G+ + + R + V +V D G YT N G+ ++ + V G
Sbjct: 14424 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 14478
Score = 33.5 bits (75), Expect = 2.0
Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582
G L+ VRG P P + W + RS A ++ + A D G Y
Sbjct: 18216 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 18275
Query: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
A N G A V V +K ++ ++ V+ + T
Sbjct: 18276 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 18314
Score = 33.5 bits (75), Expect = 2.0
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
+ L ++ G T + V+G P P++TW + + R LD I+ T F + V
Sbjct: 19701 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 19756
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
++ D GKY N G ++ T+ + V
Sbjct: 19757 NKYDAGKYILTLENSCGKKEYTIVVKV 19783
Score = 33.5 bits (75), Expect = 2.0
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
VK V S S S DP E P F + + L +K GA+ RG P
Sbjct: 26157 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 26214
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P V W + + + R +D T SL I + D GKYT N A +T+
Sbjct: 26215 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 26271
Query: 121 LTV 123
+ V
Sbjct: 26272 VKV 26274
Score = 33.5 bits (75), Expect = 2.0
Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572
S + K V G F + RG PVP + W +P R+ + L I++
Sbjct: 26190 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 26246
Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTV 600
A D G YT +N L S + V V
Sbjct: 26247 ANRNDSGKYTLTIQNVLSAASLTLVVKV 26274
Score = 33.5 bits (75), Expect = 2.0
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G
Sbjct: 26196 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 26253
Query: 692 TYTCEAWN 699
YT N
Sbjct: 26254 KYTLTIQN 26261
Score = 33.1 bits (74), Expect = 2.6
Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G KL+ + +LSV+ ++ I R+L E FE + +
Sbjct: 2513 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2560
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W+ + I ++ ++ + + L + + ++D GKYT A G + +L
Sbjct: 2561 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2615
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
TV G +SK L D+ V E Q F
Sbjct: 2616 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2640
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C++ P + WL+ L + + + L I DD+G YT V
Sbjct: 2641 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2699
Query: 242 ASMSAE 247
A + E
Sbjct: 2700 AKLKVE 2705
Score = 33.1 bits (74), Expect = 2.6
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 1725 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1770
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 11616 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 11675
Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 11676 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 11732
Query: 1831 CKAVNSLGEATCTAE 1845
C +A T E
Sbjct: 11733 CDCGTDKTKANVTVE 11747
Score = 33.1 bits (74), Expect = 2.6
Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%)
Query: 442 KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501
K EV W L V Q ++ + H L + + RD G Y A + + +
Sbjct: 12939 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 12995
Query: 502 LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561
+ AP + +D V G+ + P W +P+
Sbjct: 12996 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 13047
Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQ 591
A I +A D G Y + +N G+
Sbjct: 13048 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 13077
Score = 33.1 bits (74), Expect = 2.6
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160
+ V G+ + + V+ P I W+ N + K T + +++E + +SI KA
Sbjct: 15408 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 15467
Query: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
+ ED+G Y A N G + V V D P+
Sbjct: 15468 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 15499
Score = 33.1 bits (74), Expect = 2.6
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 17226 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 17282
Query: 1825 DDAKYTCKAVNSLGEATCTAELIV 1848
D Y+ N G T + +++V
Sbjct: 17283 DGGIYSLTVENPAGSKTVSVKVLV 17306
Score = 33.1 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575
+D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D +
Sbjct: 25796 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 25854
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
D G Y +N G S + V +K P P P+ + GL+
Sbjct: 25855 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 25896
Score = 33.1 bits (74), Expect = 2.6
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ GA+ + +G P P W + ++ D +FS L + + D G
Sbjct: 28369 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 28424
Query: 103 KYTCEATNGSGARQVTVELTV 123
KYT N SG++ +T + V
Sbjct: 28425 KYTLTVENNSGSKSITFTVKV 28445
Score = 32.7 bits (73), Expect = 3.4
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2362 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2419
Query: 1824 DDDAKYTCKAVNSLGEAT 1841
+D Y+ + +LG +T
Sbjct: 2420 EDAGNYSF-TIPALGLST 2436
Score = 32.7 bits (73), Expect = 3.4
Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F K + D V G + + G V W KD +I S I E C L I
Sbjct: 5988 FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEK-TCILEIL 6046
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
+ D +Y+C+ N G C A +V T+E
Sbjct: 6047 NSTKRDAGQYSCEIENEAGRDVCGA--LVSTLE 6077
Score = 32.7 bits (73), Expect = 3.4
Identities = 50/218 (22%), Positives = 85/218 (38%), Gaps = 16/218 (7%)
Query: 860 WLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIP 919
W E+ E V + R E + E + + EV + ++ +K+ + K +
Sbjct: 9495 WSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIIS------KRVE 9548
Query: 920 AEQMDFRANLQRQV--KPKTVSE-EERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKP 976
AE + ++++ KPK ++ EE + + V KK + P EKVPPPK
Sbjct: 9549 AEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPK- 9607
Query: 977 ATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKP-AETL 1035
P+ +KK+P + E L AK E ++ + A P A
Sbjct: 9608 -VPEEPKKPVPEKKVPPK-VIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVP 9665
Query: 1036 KPMGNAKPAE---TLKPMGNAKPDENLKSASKEELKKD 1070
+ A P E LKP +P + K +K++
Sbjct: 9666 EEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEE 9703
Score = 32.7 bits (73), Expect = 3.4
Identities = 76/338 (22%), Positives = 111/338 (32%), Gaps = 62/338 (18%)
Query: 932 QVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSK--------TPVPEKVPPPKPATPDFRS 983
+V K V E++ V +P++V+ + K TPVP+KV P P P R
Sbjct: 10034 EVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKRE 10093
Query: 984 VLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKP 1043
+ LP E E + V + L + P + + E L P
Sbjct: 10094 PVPVPVALPQEEEVLFEEEI----VPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPP 10149
Query: 1044 AETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQK 1103
E P E + +EE+ +VK V P K+K
Sbjct: 10150 EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKV----------------PVPAPVPEIKKK 10193
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI------ 1157
+ + V KK PPA + K IIL +E + V +
Sbjct: 10194 VTEKKVVIPKK-------EEAPPAKV---PEVPKKVEEKRIILPKEEEVLPVEVTEEPEE 10243
Query: 1158 ----EKALPEDRGLYK-----------CVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202
E+ +PE+ + V K +A V+ PA + K PE K
Sbjct: 10244 EPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEK 10303
Query: 1203 SRRP--KSSLPPVLGTESDATVKKKPAPKTPPKAAMPP 1238
P K PP E V +K P K A+PP
Sbjct: 10304 VPVPVQKKEAPPAKVPEVPKKVPEKKV-LVPKKEAVPP 10340
Score = 32.7 bits (73), Expect = 3.4
Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163
G ++ + + P W +GK K K + L + + I +
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 15884
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
G Y AKN AGQ +C+V V D P
Sbjct: 15885 HTGKYSITAKNKAGQKTANCRVKVMDVP 15912
Score = 32.7 bits (73), Expect = 3.4
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1830
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 29062 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 29119
Query: 1831 CKAVNSLG 1838
N+ G
Sbjct: 29120 LTVKNASG 29127
Score = 32.3 bits (72), Expect = 4.4
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 1765 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 12559 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 12614
Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
D Y V +G A A L V
Sbjct: 12615 LQDMGTY----VVMVGAARAAAHLTV 12636
Score = 32.3 bits (72), Expect = 4.4
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 614 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
P+ AP + L L + G +T + SG P P+V W + ++ E + H
Sbjct: 16808 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 16867
Query: 672 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702
+ T +L ++++ + D+G Y NS G
Sbjct: 16868 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 16898
Score = 32.3 bits (72), Expect = 4.4
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575
KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+
Sbjct: 21468 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 21526
Query: 576 EDHGTYTCLAENALG 590
D G YT A N G
Sbjct: 21527 RDSGAYTLTATNPGG 21541
Score = 32.3 bits (72), Expect = 4.4
Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584
G + + + G P+P++T +G P++ AE +++++++ D G Y
Sbjct: 26491 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 26550
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635
A N+ G + V ++ P PT P+ + +++ V
Sbjct: 26551 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 26597
Query: 636 DGSQVT 641
GSQVT
Sbjct: 26598 GGSQVT 26603
Score = 32.3 bits (72), Expect = 4.4
Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
P + L+ +K G+ V + +SG P P + W + E+Q + E S
Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 26929
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
+ I++ ++G Y + N+ G A + VQ
Sbjct: 26930 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 26961
Score = 32.3 bits (72), Expect = 4.4
Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
+P + + + G + + G P P +W G + R ++ + L I
Sbjct: 29743 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 29801
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
D G+YT E N +G T+++ +
Sbjct: 29802 TIRDTGEYTLELKNVTGTTSETIKVII 29828
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 1760 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2233
Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ D Y+C V T TA+LIVE
Sbjct: 2234 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2263
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)
Query: 1694 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1746
W K G V+ I + S M +I ++ K G+ + + A L + VS +
Sbjct: 2388 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2445
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
+ + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2446 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2492
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 1763 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1819
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 18611 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 18666
Query: 1820 DVCGDDDAKYTCKAVNSLGE 1839
+ DD KY+ VN GE
Sbjct: 18667 NSTRDDSGKYSLTLVNPAGE 18686
Score = 32.0 bits (71), Expect = 5.8
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786
R++ G S+ I I G P P V W +D L K+ + E N + FT L++ +
Sbjct: 20784 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 20839
Query: 787 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819
+ G++ + ++N G+ S V++ + ++ L
Sbjct: 20840 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 20872
Score = 32.0 bits (71), Expect = 5.8
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773
Query: 1824 DDDAKYTCKAVN 1835
D +Y K N
Sbjct: 24774 TDGGQYILKLSN 24785
Score = 32.0 bits (71), Expect = 5.8
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
K G+ + + G P P+VTW + R + + +L + D G+Y
Sbjct: 28660 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 28718
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
N +G + +V + V G G VS + E+ WGE
Sbjct: 28719 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 28770
Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+
Sbjct: 28771 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 28823
Score = 31.6 bits (70), Expect = 7.6
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 19996 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 20054
Query: 1831 CKAVNSLG--EATCTAELI 1847
N G E T + +++
Sbjct: 20055 ITLKNVAGTKEGTISIKVV 20073
Score = 31.6 bits (70), Expect = 7.6
Identities = 19/80 (23%), Positives = 30/80 (37%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V +T ++ G P P+V W +G + +E+ L + D G
Sbjct: 24719 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778
Query: 485 YSCTASNAQGQLSCSWTLQV 504
Y SN G S T++V
Sbjct: 24779 YILKLSNVGGTKSIPITVKV 24798
Score = 31.6 bits (70), Expect = 7.6
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694
G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y
Sbjct: 24722 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 24780
Query: 695 CEAWNSAG 702
+ N G
Sbjct: 24781 LKLSNVGG 24788
Score = 31.2 bits (69), Expect = 9.9
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 1158 EKALPEDRGLYKCVAKND--AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1215
EK +P + K V + + A E ++ V+ E + PE + R P + +P VL
Sbjct: 10447 EKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVE-----EKVRVPE-EPRVPPTKVPEVLP 10500
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPED 1246
+ KK P P A PP++ + P++
Sbjct: 10501 PKEVVPEKKVPVPPAKKPEAPPPKVPEAPKE 10531
Score = 31.2 bits (69), Expect = 9.9
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 1076 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1135
NC+ + T K E A F K Q++ + EG+K C +S + + W +
Sbjct: 12533 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 12588
Query: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
KTL++ + +G + ++ A +D G Y + G A + +TV
Sbjct: 12589 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 12636
Score = 31.2 bits (69), Expect = 9.9
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 20784 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 20840
Query: 1825 DDAKYTCKAVNSLGE 1839
D K+ N G+
Sbjct: 20841 DTGKFVMTIENPAGK 20855
Score = 31.2 bits (69), Expect = 9.9
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 685
L V G + + V + G P PEV W L N I+ +E F L I E
Sbjct: 20786 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 20837
Query: 686 FPEDTGTYTCEAWNSAGE 703
DTG + N AG+
Sbjct: 20838 NRYDTGKFVMTIENPAGK 20855
Score = 31.2 bits (69), Expect = 9.9
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1830
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 21137
Query: 1831 CKAVNSLGE 1839
A N +GE
Sbjct: 21138 LTARNIVGE 21146
Score = 31.2 bits (69), Expect = 9.9
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
+V G++ + ++G P PT+ W +DGK L + T E+ + LV K
Sbjct: 21470 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 21528
Query: 789 AGQYEILLKNRVG 801
+G Y + N G
Sbjct: 21529 SGAYTLTATNPGG 21541
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 25796 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 25854
Query: 1824 DDDAKYTCKAVNSLG 1838
D +Y N G
Sbjct: 25855 RDTGQYVLTLKNVAG 25869
Score = 31.2 bits (69), Expect = 9.9
Identities = 19/71 (26%), Positives = 30/71 (42%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V V+ G + I+G+P P+VT + VPL+ + R + + + D G
Sbjct: 26486 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 26545
Query: 230 VYTCLVVNGSG 240
Y N SG
Sbjct: 26546 RYEITAANSSG 26556
Score = 31.2 bits (69), Expect = 9.9
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1830
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 28372 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 28427
Query: 1831 CKAVNSLGEATCT 1843
N+ G + T
Sbjct: 28428 LTVENNSGSKSIT 28440
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 583
V +G L ++G P P W GQ I + A EL I++A D GTY
Sbjct: 30148 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 30207
Query: 584 LAENALGQ 591
+ EN G+
Sbjct: 30208 VLENKCGK 30215
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 295 bits (755), Expect = 3e-79
Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154
AP FK++L++++V L C+V+ P + W GK + K+ I +G
Sbjct: 24622 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24681
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
+ I +D +Y+ A N G + + V+
Sbjct: 24682 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24715
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
P K +P + +R GE V + +G TW K
Sbjct: 24716 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24759
Query: 1275 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
+ I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP
Sbjct: 24760 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24819
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393
P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V +
Sbjct: 24820 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24878
Query: 1394 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453
L Y+FRV A N +G S+PS+ SE T E + E D+ EV +
Sbjct: 24879 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24935
Query: 1454 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513
++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+
Sbjct: 24936 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24994
Query: 1514 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573
N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E +
Sbjct: 24995 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 25054
Query: 1574 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633
+++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV
Sbjct: 25055 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 25114
Query: 1634 NYEPIGYATDMWSIGVICYIL--------------------------------------- 1654
++ + ATDMWS+G + Y+L
Sbjct: 25115 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 25174
Query: 1655 ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1702
+R+ ++ LQHPWL + + + K + + ++Y +K N V
Sbjct: 25175 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25233
Query: 1703 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1762
+ R+S I +S G + + +E VS + AV EE HVK
Sbjct: 25234 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25281
Query: 1763 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
+ CKIE Y +V W+ + + S ++I Y EDG L + D+
Sbjct: 25282 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25326
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
DD Y CK VN GE + AEL V+ + E
Sbjct: 25327 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25358
Score = 164 bits (416), Expect = 6e-40
Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%)
Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
+VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++
Sbjct: 26443 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26502
Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
+ S K+ Q T+ + A E S P T L
Sbjct: 26503 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26557
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y
Sbjct: 26558 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26617
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285
TC V N +G S S +L+I+ + V K + + V++E++ + ++
Sbjct: 26618 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 26677
Query: 286 DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
EA ++ SK S + S + +K + RT +
Sbjct: 26678 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 26737
Query: 337 VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388
T SI + R+ + G GV + EE + T +Q
Sbjct: 26738 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26795
Query: 389 LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
+ + +SK + + + S P F S+P+SQ + E Q V F CE+SG
Sbjct: 26796 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 26855
Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
P PE+ WF P+ ++ + + L + A DSG Y+ A N +GQ CS
Sbjct: 26856 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 26912
Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560
T + L ++E PS VL+ D LQ S + Q +Q + S
Sbjct: 26913 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 26954
Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613
EA + A + ++ ++ ++S S+++ + S +
Sbjct: 26955 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 27014
Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671
A + P SD+ + +G +T+ +G P PEV W G +I QE FH
Sbjct: 27015 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 27074
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
E +L I +V +D G YT N G
Sbjct: 27075 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 27105
Score = 158 bits (400), Expect = 4e-38
Identities = 188/837 (22%), Positives = 311/837 (37%), Gaps = 176/837 (21%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ VA + S +L V+ E P + + + ++ G A+F + G P+
Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221
Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P+++W++ Q +++G + FL D ++L++ ED YTCEA N G +
Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
L+VE P V + PP T L V EGQ R
Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F C+++G +V+W + ++PS +++ LEI +D G YT + N
Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376
Query: 240 GKASMSAELS--IQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
G+ S +A LS +Q LD +++ DVR+ + +S E+ K
Sbjct: 3377 GQVSSTANLSLEVQALD---------RQSSGKDVRESAKSQAVADSSFTKEESKISQKEI 3427
Query: 298 SSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEP- 356
S Q G S + + V + S S AA VQ
Sbjct: 3428 KSFQ-GSSYEY-------------------------EVQVFESVSQSSIHTAASVQDTQL 3461
Query: 357 -RAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPK 415
L ++ S E K A + +T + L QDV K +
Sbjct: 3462 CHTASLSQIAESTELSKECA--KESTGEAPKIFLHLQDVTVKCGD--------------- 3504
Query: 416 FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
T +F C + +V W EG + E ++ ++ +L +
Sbjct: 3505 --------------TAQFLCVLKDDSFIDVTWTHEGAKIEESE-RLKQSQNGNIQFLTIC 3549
Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
+ D G YSC N G+ + S AV+ V + S+L +
Sbjct: 3550 NVQLVDQGLYSCIVHNDCGERTTS--------AVLSVEGAPESILHE------------- 3588
Query: 536 SVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQD-ALPEDHGTYTCLAENALGQVSC 594
RI + + +++ S A LH + L + + T L+E+
Sbjct: 3589 --------RIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSES------- 3633
Query: 595 SAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
V+ K + E T PIF++ +S+ + G T++V V G P P++
Sbjct: 3634 ----PVYPTKFDSEKE---------GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKI 3680
Query: 655 IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ- 713
W NG + S D+ F G HSL I ED G YTC A N G+ A L +
Sbjct: 3681 QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3740
Query: 714 --EPHDGTQ-----------------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHW 754
E H T+ P F+ + + + + G + + G+P PTV W
Sbjct: 3741 KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTW 3800
Query: 755 LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
++ K LC + + T ++ Q +G Y +N +GE +C L++
Sbjct: 3801 FKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 134 bits (336), Expect = 1e-30
Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%)
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
S + P + S+ P + Q V + KF + +G P+P W +G +
Sbjct: 26529 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 26588
Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
Q G ++ ED G +L + K T DSG Y+CT N+ G +S S L ++
Sbjct: 26589 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 26637
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+KD E Q Q + TP + ++ + Q A + E ++E Q+ L
Sbjct: 26638 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 26689
Query: 576 -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631
++ + ++E + S + VHE+ K+S+ SE + A K + +
Sbjct: 26690 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 26742
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + +G ++ + ++G +V W+ NG E+ SE++ + G+ +L I++ D G
Sbjct: 26743 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26800
Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
TC + G V+ Q LT+ + P FIS+PRS + GQ+VL +C I+G+P P
Sbjct: 26801 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26859
Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
+ W ++ + + + + ++ +V++L ++ +G+Y I KN G+CS SLM+
Sbjct: 26860 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918
Query: 812 QNSSARALPRGREPA 826
LP EP+
Sbjct: 26919 -------LPLVEEPS 26926
Score = 122 bits (306), Expect = 3e-27
Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++
Sbjct: 23846 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23902
Query: 795 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848
+L+N+ G+ + + + + S P G P +D+ V AD GG+D G
Sbjct: 23903 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23958
Query: 849 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906
+ W + VRG +++ E R Q L + V+
Sbjct: 23959 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 24016
Query: 907 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963
KT L+ + P E +D + + + +V + ++ + K +
Sbjct: 24017 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 24075
Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022
KT + + PD + ++ A+N +ET A + V P G
Sbjct: 24076 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 24131
Query: 1023 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070
L+ + +K + TL KP K D K ++KE +K
Sbjct: 24132 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 24191
Query: 1071 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
+N+ R T + K + G AP +++++DV G+ L CQ
Sbjct: 24192 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24250
Query: 1121 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180
+ P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E
Sbjct: 24251 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24310
Query: 1181 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
S ++ + P P P K
Sbjct: 24311 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24330
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299
E G ++ L G TW +K +Q SE++ +EN+E+ + L +
Sbjct: 24331 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24386
Query: 1300 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG
Sbjct: 24387 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24446
Query: 1360 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P +
Sbjct: 24447 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24506
Query: 1418 ESELTTVGEKPEEP 1431
S + + E+P
Sbjct: 24507 VSSVVIIKSPFEKP 24520
Score = 118 bits (295), Expect = 6e-26
Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)
Query: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680
T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 681 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714
I+E F ED+G +TC A N AG V T L VQ
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 715 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
P + P+FI+KP G SV+ C + G+P P V+W + G
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 760 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ +
Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131
Query: 817 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875
L + ++ + V + G PG+ + + E+E + + K
Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186
Query: 876 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932
V R + E+ QE F + L K++ KT E+ L+E E+M +
Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242
Query: 933 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981
V+ S + ++ + + ++ V S P+P +++ + DF
Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298
Query: 982 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035
R+ L LP + G +A N K NA SG P P+G TL
Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350
Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095
+P+ + +L P ++ + A + + + S+ +
Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407
Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152
P F K EG+ +V P W +G+ + T +++ ++G+
Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467
Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212
S+ I A P D G + VA+N AG++ S +TV+
Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504
Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
+ + P ++ ++ ++ G +E+ + TG W+
Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544
Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327
K I ++ +++E ++ + L I + + YT NK G + + +VN+ V
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604
Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348
+P+P P GT A +I + L
Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631
Score = 115 bits (288), Expect = 4e-25
Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483
+ E Q + + ++G +V W L G + E Y +GS +K A RD G
Sbjct: 26745 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 26800
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
+C + +G + C + L + + + AP+F S + + EGQ+ + C + G P P
Sbjct: 26801 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26858
Query: 544 RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
I W N PI + + V L I++A D G YT A+N GQ S +A + V
Sbjct: 26859 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
LP+ +P+ + L+ D + GS + +VQ+S + +
Sbjct: 26919 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 26964
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
+ + F Q +QE F E + + N ++ + ++ G
Sbjct: 26965 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 27023
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779
P + P ++ G+ + ++CA G+P P V W G+ + ++ G F + +D+ TL
Sbjct: 27024 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 27083
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813
++ VQ G Y + L N G S V++ +++
Sbjct: 27084 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27117
Score = 115 bits (287), Expect = 5e-25
Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
F +++ + EG F CK++G P P++ W K R+ E+ M L+
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1297
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282
G+AS+ + + + +F K N I
Sbjct: 1298 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1330
Query: 283 SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342
KL +E AA G+P + +P S++ S SPR+ ++P+
Sbjct: 1331 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1369
Query: 343 SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402
R+ P +P R PA PA PG ++ R
Sbjct: 1370 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1408
Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
P F KP S + E QT +F +V G P PE WF +G +
Sbjct: 1409 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1459
Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
V ++ G+ L ++ A DSG ++ A N G+ S S L VE + +V P F LK+
Sbjct: 1460 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1518
Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577
+ EG ++ G P P I WL N P +Y + E G A L I + +D
Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578
Query: 578 HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617
YT A N G+ C V V + + + ++P AP
Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1638
Query: 618 -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662
K P F + L+ L++ +++ G+P V WLH+G
Sbjct: 1639 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714
++ + SL + D+G TC A N G T A L V++
Sbjct: 1699 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1758
Query: 715 ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744
H+G +P + P V G++ C +
Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1818
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G
Sbjct: 1819 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1876
Query: 805 CQVSLMLQNSS--ARALPRGREP 825
+V L +Q L R EP
Sbjct: 1877 HKVKLEIQQREDFRSVLRRAPEP 1899
Score = 113 bits (282), Expect = 2e-24
Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
+K S RK E L + AP + +V G + V P EV W HNG
Sbjct: 26048 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 26107
Query: 662 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682
E+QES D H + GT ++C
Sbjct: 26108 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 26167
Query: 683 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718
+ VFPE T T EA +S EV++Q T + H
Sbjct: 26168 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26227
Query: 719 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752
+ ++KPRS+T G+S SC G+P PTV
Sbjct: 26228 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26287
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q
Sbjct: 26288 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26346
Query: 813 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848
+ + ++ R + P +++
Sbjct: 26347 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26406
Query: 849 LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
L P + +L+ E +++ VL+ + T + +++ Q +
Sbjct: 26407 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26466
Query: 901 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954
++ L+E D + EI E + NLQ + K++ E+ K+ ++ D +
Sbjct: 26467 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26526
Query: 955 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983
S + +K K P P P P+P T D ++
Sbjct: 26527 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26586
Query: 984 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015
+ GGK KL + G SS+ L KA++ ++
Sbjct: 26587 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26646
Query: 1016 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067
+ Q + + P A E + A +E +K M AK E L + ASK EE+
Sbjct: 26647 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26703
Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
KK + H T + SE T K + + EG++L+L+ ++
Sbjct: 26704 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26761
Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ W LNG L ++ GS +++I++A D G+ C++K G +C +T+
Sbjct: 26762 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26821
Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247
+ E+ SDA P I P Q
Sbjct: 26822 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26838
Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
+ G++V +++G W K I S ++ + S N L I A G
Sbjct: 26839 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26898
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S
Sbjct: 26899 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26958
Query: 1368 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423
+ S++ + + + S + Q + E + + + G S +Q S++
Sbjct: 26959 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 27016
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEV 1447
G + PK E SD E +V
Sbjct: 27017 AGIRGIPPKIEALPSDISIDEGKV 27040
Score = 112 bits (279), Expect = 4e-24
Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
+N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E
Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
D G YT A+N G + +L VE A LG P TL R +P +R I
Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369
Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
P F K EGQ R
Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429
Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
F K+ GRP P+ W G + V +++G Q L I D G +T + N
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489
Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
+G++S+S L+++ ++ FV + K N I + S+L+ A + N
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538
Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
W NS P + ++E K + V Q
Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592
Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
T + ++ +PEP ++ P G R K A P P Q D+
Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453
K ++ P F+ K S +K F C ++ G P V W +G P
Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698
Query: 454 VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502
+ + + + G L A +RDSG +C A+N G S TL
Sbjct: 1699 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757
Query: 503 -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536
++E L M + + V D V+EG+ +C
Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817
Query: 537 VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594
V G P P++ W LNGQ I+ ++ G+ L I D D G AEN G +
Sbjct: 1818 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1877
Query: 595 SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
+ + +++ R +L AP +P + G +V + T + E
Sbjct: 1878 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1929
Query: 654 VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694
V+ L I +ESE+ F++R + S E + E
Sbjct: 1930 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 1989
Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738
E + E+ + + E T P F + +S T G
Sbjct: 1990 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2049
Query: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
+ G P P W ++G + + + ++V LV++ V + + N
Sbjct: 2050 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2109
Query: 799 RVGECSCQVSLMLQ 812
GE S L++Q
Sbjct: 2110 IAGETSSHAFLLVQ 2123
Score = 111 bits (278), Expect = 6e-24
Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
+PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L
Sbjct: 12593 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12651
Query: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355
I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+
Sbjct: 12652 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12711
Query: 1356 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE
Sbjct: 12712 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12771
Query: 1415 PSQESELTTVGE--KPEEPKD 1433
P ++ P EPK+
Sbjct: 12772 PLTSPKMVAQFPFGVPSEPKN 12792
Score = 110 bits (275), Expect = 1e-23
Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567
AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I + G Y+ A N GQ + +A + V K+E AP P F+Q
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168
Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713
ED+GTY+ A NS G + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 109 bits (272), Expect = 3e-23
Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)
Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58
Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
S L I AV + + G+Y+ +ATNGSG T EL V+ A
Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PP F +L + V++G R ++TG P P V + + +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
+S++ + L I +D G Y+ N G+A+ +AEL +QG
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ +A S R+T+ + + ++ + E +D AA + +P R PP +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263
Query: 312 SQPQPP 317
P PP
Sbjct: 264 RSPTPP 269
Score = 109 bits (272), Expect = 3e-23
Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y
Sbjct: 7397 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7456
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y +
Sbjct: 7457 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7515
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426
E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T +
Sbjct: 7516 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7575
Query: 1427 KPEEPKDEVEVSD 1439
P P +E SD
Sbjct: 7576 DPPGPPTRLEPSD 7588
Score = 105 bits (262), Expect = 4e-22
Identities = 101/411 (24%), Positives = 157/411 (38%), Gaps = 48/411 (11%)
Query: 415 KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
+F + +V E + F CEVS P V W + ++ + I++ ++ H L +
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3070
Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
R D+G Y+ A + +L V S+ K+ VIE Q V++
Sbjct: 3071 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3121
Query: 535 CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
V V W +G I + + E + + I + D G YT +A
Sbjct: 3122 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3178
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
+R S L AP P LQ L + V G +SG
Sbjct: 3179 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3219
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
P P++ W + F G +++L + E FPED YTCEA N G T A
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279
Query: 710 LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
L+V+ P D P + I+ + S GQ C ++G + +D K
Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3337
Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
K + F + Q ED + L + + P G Y + N VG+ S +L L+
Sbjct: 3338 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3388
Score = 104 bits (259), Expect = 9e-22
Identities = 102/419 (24%), Positives = 172/419 (41%), Gaps = 48/419 (11%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P+ + Q V+ + +F +SG P+P+++W+ E + + D + L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3251
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526
L++A D+ Y+C A N G + S +L VE V+ P+ + L+D
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311
Query: 527 EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583
EGQ QC V GT + +++W + P ++ R T +L I +A PED GTYT
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370
Query: 584 LAENALGQVSCSAWVTVHEK--------KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
+A NA+GQVS +A +++ + K R+S VA S T ++K
Sbjct: 3371 VASNAVGQVSSTANLSLEVQALDRQSSGKDVRESAKSQAVADSSFTKEESKISQKEIKSF 3430
Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 695
GS VQV + I H +Q+++ H+ + ++ + C
Sbjct: 3431 QGSSYEYEVQVFESVSQSSI--HTAASVQDTQ--------LCHTASLSQIAESTELSKEC 3480
Query: 696 EAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWL 755
A S GE P + VT G + C + D F V W
Sbjct: 3481 -AKESTGEA----------------PKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWT 3523
Query: 756 RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
+G A +++ + QN ++ L + VQ G Y ++ N GE + L ++ +
Sbjct: 3524 HEG-AKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGA 3581
Score = 102 bits (253), Expect = 5e-21
Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
+++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A
Sbjct: 20571 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20630
Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
+ + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG
Sbjct: 20631 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20690
Query: 1361 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
+ + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP
Sbjct: 20691 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20747
Query: 1417 QESEL 1421
+ +
Sbjct: 20748 ESDSV 20752
Score = 101 bits (252), Expect = 6e-21
Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)
Query: 1236 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
+PP + ++ E V+AG +V + G T W +I+ EH VE
Sbjct: 11201 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11260
Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352
S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW
Sbjct: 11261 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11320
Query: 1353 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411
DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G
Sbjct: 11321 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11380
Query: 1412 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469
P +S T K P P + V+D E V + + ++ +Y +E R
Sbjct: 11381 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11438
Query: 1470 LGSGKFGQV 1478
+GK+ +V
Sbjct: 11439 EVTGKWVRV 11447
Score = 101 bits (252), Expect = 6e-21
Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++
Sbjct: 16235 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16291
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL
Sbjct: 16292 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16351
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N
Sbjct: 16352 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16411
Query: 1410 YGTSEPSQESELTTVGE--KPEEPK 1432
YG EP + + P+ PK
Sbjct: 16412 YGVGEPLESEPVVAKNPFVVPDAPK 16436
Score = 101 bits (251), Expect = 8e-21
Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)
Query: 1243 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302
F + VRAG S+ LF G T W K + S + +++ S LT+ +
Sbjct: 22058 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 22115
Query: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362
G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+
Sbjct: 22116 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 22174
Query: 1363 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421
+ Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E
Sbjct: 22175 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22234
Query: 1422 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471
E+P P+ D V+ S +P+ D + QK SDF+ +E
Sbjct: 22235 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22293
Query: 1472 SGKFGQVFRLVEK 1484
V RLVEK
Sbjct: 22294 KQLTFTVERLVEK 22306
Score = 100 bits (250), Expect = 1e-20
Identities = 133/588 (22%), Positives = 220/588 (37%), Gaps = 101/588 (17%)
Query: 63 QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119
+V W+ + + S +F L D + T++LVI V+ ED +G+Y CEA N SG +
Sbjct: 4463 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4519
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
+LTV A PV+ + K+ + V G + +
Sbjct: 4520 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4547
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F+C+I P + W K + S + S+ + LEI D G YTC N
Sbjct: 4548 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4607
Query: 240 GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294
G S +A L ++ G + R + E K + ++EV +V+ K + + + K
Sbjct: 4608 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4664
Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
+ P PP P+P E ++ + R P+ + + +I L A +P
Sbjct: 4665 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4718
Query: 355 EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414
+P A + P E P P T P ++ +AA + P++G
Sbjct: 4719 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4777
Query: 415 KFES-----KPQSQEVKENQTVKFRCEVSGIP---------------------------- 441
E+ +P S K F ++ +P
Sbjct: 4778 PIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLV 4837
Query: 442 KPEVA---WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
P A W +G+ + R+ D L ++ + D+G Y+C + +
Sbjct: 4838 SPSTAITTWMKDGSNI-RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTS 4896
Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
+ L VE L V V ++ ++ V++GQ L C + + W +G+ +
Sbjct: 4897 TAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKP 4950
Query: 559 STCEAGV----AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
GV L I DA D GTYT ENA + CS+ V V E
Sbjct: 4951 GRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKVVE 4997
Score = 100 bits (250), Expect = 1e-20
Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L +
Sbjct: 15160 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15219
Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
+ G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG
Sbjct: 15220 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15279
Query: 1361 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
+ + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP +
Sbjct: 15280 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15339
Query: 1420 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471
+ V P+ PK+ EV D P+ D + IN Y +E R
Sbjct: 15340 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15389
Query: 1472 SGKFGQVFRLVEKKT 1486
K GQ + KKT
Sbjct: 15390 -DKAGQRWIKCNKKT 15403
Score = 100 bits (249), Expect = 1e-20
Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y
Sbjct: 15854 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15913
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y +
Sbjct: 15914 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15973
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
E D++ TW+ + AT T+ L EY+FR+ A N YG S
Sbjct: 15974 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 16019
Score = 100 bits (248), Expect = 2e-20
Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)
Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567
V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A
Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623
L I LPED G YT A N G CS + V Y L PV+ + +P
Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362
Query: 624 -------------------------------------------------IFLQGLSDLKV 634
+F+ K
Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481
Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
+T A N AG +LTV+ +P F+ K ++V G + + G+P P +
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541
Query: 753 HWLRD 757
WL++
Sbjct: 1542 VWLKN 1546
Score = 100 bits (248), Expect = 2e-20
Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A++ S +L +V +PL FI P ++ + E AKFE V P+
Sbjct: 5513 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5563
Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
W + Q IT RF L+ G + + + A +E + + E + SG
Sbjct: 5564 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5622
Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
+ VT + F +L + KT F
Sbjct: 5623 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5682
Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
+++ I E P F KL E C+I+ P
Sbjct: 5683 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5742
Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248
V W K ++PS + ++L + + D+G YTC G+ K S ++
Sbjct: 5743 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 5799
Query: 249 ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287
S++ +++ F ET+ + D+ + I +E K+ S
Sbjct: 5800 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 5857
Query: 288 LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341
L NC Q GG AAN + K L KD TA +T
Sbjct: 5858 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 5913
Query: 342 SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395
S L+ +++P + + P E + R + G +
Sbjct: 5914 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 5963
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
+K + + +F + Q V+E T CEVS +V WF GT +
Sbjct: 5964 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 6020
Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
+ + E+ D L + D TY+C A + + SC+ L V+
Sbjct: 6021 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 6070
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572
F L D V E + +C + ++ W +G I+ + + V L I
Sbjct: 6071 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 6129
Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632
L +D Y+C A S +TV E+++ +F + L+++
Sbjct: 6130 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 6167
Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
+V + + + +VS P EVIW EI E+ + G + L IQ ED G
Sbjct: 6168 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6226
Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
Y C +S RT + V E FISKP+++ G+ C+I+ + FP V
Sbjct: 6227 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 6277
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796
W RD K L + ++V+ + LV+K G Y +++
Sbjct: 6278 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 6320
Score = 100 bits (248), Expect = 2e-20
Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288
MPP I E +V G +V + K+ G T TW K ++ + H+
Sbjct: 9811 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9869
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348
++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + +
Sbjct: 9870 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9929
Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407
TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A
Sbjct: 9930 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9989
Query: 1408 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
N YG EP + +PE ++ V + D V ++T+N E+ D
Sbjct: 9990 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 10038
Score = 99.8 bits (247), Expect = 2e-20
Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%)
Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343
E + +K PQR S P +P P E+ +++ ++KT+
Sbjct: 693 ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 750
Query: 344 SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403
T + V PR SP K P G + ++ +A +
Sbjct: 751 LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 796
Query: 404 PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463
E S+ K ++ VK ++T R P P+ F + + E +EV
Sbjct: 797 QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 852
Query: 464 YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523
++ G + + R+ A+ + VE + P+ S LK+
Sbjct: 853 KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 906
Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580
VIEG+ L+C + G P P +TW I+ + + T ++G+A L I++A ED G
Sbjct: 907 TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 966
Query: 581 YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614
+TC A N G VS S ++ V EK+++ +E
Sbjct: 967 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1026
Query: 615 -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671
P +P AP F+ K+++G V QV GNP P V W +G + + +
Sbjct: 1027 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1086
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
++ + L I F +D G YT N GE A L + ++
Sbjct: 1087 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132
Score = 99.4 bits (246), Expect = 3e-20
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++
Sbjct: 17318 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17374
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351
+ L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+
Sbjct: 17375 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17434
Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410
W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y
Sbjct: 17435 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17494
Query: 1411 GTSEPSQES 1419
G EP + +
Sbjct: 17495 GVGEPLESA 17503
Score = 97.8 bits (242), Expect = 9e-20
Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%)
Query: 426 KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+E VK+ C++ + +V W+ + E YED G L + D GT
Sbjct: 25275 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 25333
Query: 485 YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522
Y C N G+ S C T++ + + ++E P F+ L +
Sbjct: 25334 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 25393
Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576
G++ ++ P P +TW +GQ I+ + + G+ +L I +
Sbjct: 25394 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25453
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
D YT +A N G+ SC A +TV L P P+F + L++ + +
Sbjct: 25454 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 25503
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695
G V ++VSG PPP + W +G + + G ++L I++ PEDTG Y
Sbjct: 25504 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25563
Query: 696 EAWNSAGEVRTQAVLTVQ 713
A N+AG QA L V+
Sbjct: 25564 TATNTAGSTSCQAHLQVE 25581
Score = 97.4 bits (241), Expect = 1e-19
Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y
Sbjct: 21270 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21329
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T++++N + + + + P P G +I++ S+ LSW +GG + YSI
Sbjct: 21330 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21389
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 21390 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21437
Score = 97.4 bits (241), Expect = 1e-19
Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI
Sbjct: 26069 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 26128
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278
+ DD G Y + N G+AS A L + G D + R + V E+T
Sbjct: 26129 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 26188
Query: 279 --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
+S K +EA++ + S + + S + ++++S ++ +
Sbjct: 26189 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 26245
Query: 337 VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396
+K +++ AAR+ +PR+ + GE + PT L V+S
Sbjct: 26246 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 26297
Query: 397 KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450
+A ++ + + + S S E V EN K E + I K V
Sbjct: 26298 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 26355
Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509
+P R + V +K+ R S S + + + + T +V+ L V
Sbjct: 26356 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26409
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563
P + LK A + L C V + + +TW +G+ ++ +
Sbjct: 26410 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26466
Query: 564 GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609
G EL I + D G Y C G Q A+ ++HEK KS +K+
Sbjct: 26467 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26526
Query: 610 EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
++P AP + + GL D V S V+ +G P P IW +G
Sbjct: 26527 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26586
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
I + + + L I + D+G YTC NSAG V + LT++ D
Sbjct: 26587 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26641
Score = 96.7 bits (239), Expect = 2e-19
Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 13061
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y +
Sbjct: 13062 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 13120
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
+ +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P
Sbjct: 13121 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 13168
Score = 96.7 bits (239), Expect = 2e-19
Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%)
Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
K + I+KTS + + R + E AF + I EG + + G + V
Sbjct: 26713 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26763
Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
W NG +T+ + G+ G+ +L I D G TC + G + +LT+
Sbjct: 26764 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26821
Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
SK L D APA ++P + EGQ F+C+
Sbjct: 26822 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26851
Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S
Sbjct: 26852 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26911
Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
+A L + L V + V+ + S SL+ +++S S+ +
Sbjct: 26912 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26954
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
+ S ++S E K S ++ Q ++ +SSS +
Sbjct: 26955 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26999
Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
G+ + + E S + KA R IP PK E+ P
Sbjct: 27000 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 27031
Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480
+ E + + C +G P PEV W G + QE G + L ++ + +
Sbjct: 27032 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 27091
Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERL 507
D G Y+ + N G S + + + +
Sbjct: 27092 DGGLYTLSLGNEFGSDSATVNIHIRSI 27118
Score = 96.3 bits (238), Expect = 2e-19
Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)
Query: 1228 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
P T PP + + F + +R GE+ L G+ +G +W K + E + +
Sbjct: 10503 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10562
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346
+ + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++
Sbjct: 10563 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10622
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405
+ +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+
Sbjct: 10623 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10682
Query: 1406 AINVYGTSEPSQESELTT-----VGEKPEEP 1431
A N+YG S+P + V + P++P
Sbjct: 10683 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10713
Score = 95.9 bits (237), Expect = 3e-19
Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
+G + + + K P P I D V GE + + T +W K
Sbjct: 8061 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 8117
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P
Sbjct: 8118 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 8177
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392
ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+
Sbjct: 8178 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8236
Query: 1393 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449
DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + +
Sbjct: 8237 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8295
Query: 1450 RTVTINTEQKVSDFYDIEERLGSGK 1474
+ + K+ + I E++ G+
Sbjct: 8296 KPPLYDGGSKIMGY--IIEKIAKGE 8318
Score = 95.9 bits (237), Expect = 3e-19
Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%)
Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561
++A +E+ P ++ EG C + ++TW + ++ + T
Sbjct: 25256 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25314
Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608
E GVA L+++D D GTY C N G+ S A + V KK R+
Sbjct: 25315 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25374
Query: 609 SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
++ + L P + T P++ + G V V ++ +P P V W +G +I+ +
Sbjct: 25375 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25429
Query: 668 D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720
+ + FE + L I V +D YT A N GE +A LTV P D T +
Sbjct: 25430 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25489
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
P F + GQSV ++G P PT+ W +DG+ L + + D + L
Sbjct: 25490 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25549
Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
++ P G Y + N G SCQ L ++
Sbjct: 25550 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25581
Score = 95.5 bits (236), Expect = 4e-19
Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)
Query: 1249 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G
Sbjct: 14085 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14144
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY
Sbjct: 14145 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14203
Query: 1368 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
+E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q +
Sbjct: 14204 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14260
Query: 1424 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
V P P ++ EVS+ V T T++ ++ V D
Sbjct: 14261 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14293
Score = 94.7 bits (234), Expect = 7e-19
Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VRAG S+ +F + G TW K I +EN+E+ + L I + G +
Sbjct: 14483 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14540
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y +
Sbjct: 14541 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14599
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E
Sbjct: 14600 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14659
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478
P P D + + D + + + + K++ + +R GS ++ +
Sbjct: 14660 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14709
Score = 94.7 bits (234), Expect = 7e-19
Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++
Sbjct: 19481 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19537
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L
Sbjct: 19538 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19597
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N
Sbjct: 19598 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19657
Query: 1410 YGTSEP 1415
YG EP
Sbjct: 19658 YGVGEP 19663
Score = 94.4 bits (233), Expect = 9e-19
Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
+RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y
Sbjct: 23153 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23210
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y +
Sbjct: 23211 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23269
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E
Sbjct: 23270 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23329
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
P P ++EV D V TVT+ E+ + D
Sbjct: 23330 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23356
Score = 94.0 bits (232), Expect = 1e-18
Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y
Sbjct: 19101 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19160
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y +
Sbjct: 19161 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19219
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E
Sbjct: 19220 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19277
Query: 1428 PEEP 1431
P P
Sbjct: 19278 PFSP 19281
Score = 93.2 bits (230), Expect = 2e-18
Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 1250 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301
+AG + + + G +W K +K +++ H ++E +EN S + I +
Sbjct: 9518 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9577
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+ H G Y++ +NK G + A + V+D P PP SDI S LSW DGG
Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9636
Query: 1362 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + +
Sbjct: 9637 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9696
Query: 1421 LTTVGEK--PEEPKDEVEV 1437
TT + P +P ++++
Sbjct: 9697 RTTARDPIYPPDPPIKLKI 9715
Score = 92.4 bits (228), Expect = 4e-18
Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
+ P F +L +K A FE R+ G P V W +G+P+ + R + G
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
SL + D G TC ATN G + L V E S ++ P K L
Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773
Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
+ ++ G + P V V EG+ RF C++TG PQP+V W
Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
++ S R V +G+ L+I D G N G +L IQ + RS
Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891
Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
+R + + E K+D ++K +R +
Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951
Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
SK + + T V K+ ++ + EE+K A
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
T PT +P +I + ++ PK + QSQ V + FR V
Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2056
Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
G P PE W+ G + R + + + L + DS + A N G+ S
Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2116
Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557
L V+ ++ +F+ L+D E P ++ W +G +
Sbjct: 2117 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2172
Query: 558 --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
R + V L I D Y+C V V ++ ++ ++
Sbjct: 2173 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2218
Query: 616 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672
A + F++ L D++V + + VS PE I W HN E++ + +
Sbjct: 2219 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2269
Query: 673 QRGTQHSLCIQEVFPEDTGTYT 694
R + +L +++V ED G Y+
Sbjct: 2270 SRRGRQNLTVKDVTKEDQGEYS 2291
Score = 92.4 bits (228), Expect = 4e-18
Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290
P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++
Sbjct: 18400 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18456
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ L + + G Y L + N G++ + + V+D+P PP G + + + L
Sbjct: 18457 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18516
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N
Sbjct: 18517 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18576
Query: 1410 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438
YG EP + +T KP P EVS
Sbjct: 18577 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18606
Score = 92.4 bits (228), Expect = 4e-18
Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
T + TV+ T + MP + I P AG VEL + G P +W
Sbjct: 23418 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23471
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
+++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP
Sbjct: 23472 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23531
Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394
G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L
Sbjct: 23532 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23591
Query: 1395 LPDHEYKFRVRAINVYG 1411
+EY FRV A N +G
Sbjct: 23592 TEGNEYVFRVAATNRFG 23608
Score = 92.0 bits (227), Expect = 5e-18
Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+P+T P + +N+ + EG + E + GYP P VTW+R I S F +
Sbjct: 892 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
G L+I ED G++TC A N +G + L V+ S + V++ T R
Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009
Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
F S V T S+ E P F TK + EG F C++ G P+P V W
Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069
Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
K VPL R VS +++ G L I DD G YT +V N G+ S SA L
Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 92.0 bits (227), Expect = 5e-18
Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
+AGE V++ G P T TW K K + +EN+++ S LTI + G Y
Sbjct: 20979 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 21038
Query: 1310 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I
Sbjct: 21039 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21097
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E
Sbjct: 21098 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 21157
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474
P P ++ + D + + + + ++++ + ER G G+
Sbjct: 21158 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21201
Score = 91.7 bits (226), Expect = 6e-18
Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y
Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16995
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y +
Sbjct: 16996 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 17055
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
+ D+ W + AT T+ V L EY+FR+ A N YG S
Sbjct: 17056 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17101
Score = 91.3 bits (225), Expect = 8e-18
Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)
Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301
KV+AGE V + VTG W K I++ +V SE ++L+I A
Sbjct: 9104 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9163
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS
Sbjct: 9164 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9222
Query: 1362 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418
+ Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ +
Sbjct: 9223 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9282
Query: 1419 SEL 1421
++
Sbjct: 9283 DKV 9285
Score = 91.3 bits (225), Expect = 8e-18
Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)
Query: 1226 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
P P PP++I +Q ++ G+++ L + G TW K +
Sbjct: 10899 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10958
Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
+ V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+
Sbjct: 10959 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 11015
Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401
IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y
Sbjct: 11016 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 11075
Query: 1402 FRVRAINVYG 1411
FRV A N YG
Sbjct: 11076 FRVAAENQYG 11085
Score = 91.3 bits (225), Expect = 8e-18
Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)
Query: 1232 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
PKA +PP+I + +KV RA ++ LF + G W R + +
Sbjct: 15544 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15601
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
+E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++
Sbjct: 15602 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15660
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
+S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV
Sbjct: 15661 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15720
Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431
A N YG P++ +E E+P P
Sbjct: 15721 LAENEYGIGLPAETAESVKASERPLPP 15747
Score = 90.5 bits (223), Expect = 1e-17
Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)
Query: 1249 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
V AG + + V+G P T TW M R QE+ +E + S + I ++ H G
Sbjct: 10231 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10287
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y
Sbjct: 10288 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10346
Query: 1367 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
IE +S + W + T + VQ L+ Y FR+ A N G + SE +
Sbjct: 10347 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10406
Query: 1426 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475
E PE P+D +EV EV TVT+ D Y +E RL G+ KF
Sbjct: 10407 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10458
Query: 1476 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524
K T + + KE + +S +N + K C
Sbjct: 10459 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10500
Score = 90.1 bits (222), Expect = 2e-17
Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
+RAG S+ LF + G W K +I+++ + V +S + L + + G Y
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16706
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y +
Sbjct: 16707 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16765
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E
Sbjct: 16766 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16825
Query: 1428 PEEP 1431
P+ P
Sbjct: 16826 PQPP 16829
Score = 90.1 bits (222), Expect = 2e-17
Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)
Query: 1228 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278
P P +++++P+ D++ + G V G + T PI C W K + I
Sbjct: 23813 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23872
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G
Sbjct: 23873 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23930
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397
DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L +
Sbjct: 23931 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23990
Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454
EY FRV A N +G S+P + E T PE P + EV D + + +
Sbjct: 23991 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 24050
Query: 1455 NTEQKVSDFY 1464
+ +V+ +Y
Sbjct: 24051 DGGSRVTGYY 24060
Score = 89.4 bits (220), Expect = 3e-17
Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)
Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679
AP F Q L + V++GS T +SG P PEV W +G I S +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122
Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
+ + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 800 VGECSCQVSLMLQ 812
VG + L++Q
Sbjct: 182 VGRATSTAELLVQ 194
Score = 89.0 bits (219), Expect = 4e-17
Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%)
Query: 408 QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467
Q++ P P+ V E +T +FRC V+G P+P+V W+L G +R+ + Y+
Sbjct: 1789 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1846
Query: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527
G HYL ++ ++ D+G TA N +G + L++++ F SVL+
Sbjct: 1847 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1900
Query: 528 GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+ V LQ V+ P + L + I + + E+ EL +
Sbjct: 1901 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 1958
Query: 576 EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618
+ G Y + E L + W E+K + E + +
Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2018
Query: 619 KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
KP AP + + V GS V+V G P PE W NG +I+ S+
Sbjct: 2019 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2078
Query: 670 H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728
+ + L I++V ED+ + +A N AGE + A L VQ T F + +
Sbjct: 2079 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2135
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758
V A ++ +PF V W +DG
Sbjct: 2136 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2165
Score = 87.8 bits (216), Expect = 9e-17
Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)
Query: 1232 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285
PK + P I + VRAG + LF V G TW K +++ +
Sbjct: 12292 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12348
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+
Sbjct: 12349 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12407
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
+S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV
Sbjct: 12408 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12467
Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431
A+N YG P+ + + EP
Sbjct: 12468 TAVNEYGPGVPTDVPKPVLASDPLSEP 12494
Score = 87.8 bits (216), Expect = 9e-17
Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)
Query: 1228 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
P P P I+ PE + +RAG ++ L+ V G P TW K +
Sbjct: 13370 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13429
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
++ + +++++ + L + G Y L +EN G ++ + + V+D P PP
Sbjct: 13430 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13488
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397
+I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L
Sbjct: 13489 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13548
Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428
Y FRV A N YG +P + + + P
Sbjct: 13549 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13579
Score = 87.8 bits (216), Expect = 9e-17
Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)
Query: 1237 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
PP+I + +KV RA ++ LF + G W K + ++ ++E + + +
Sbjct: 18799 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18856
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW
Sbjct: 18857 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18915
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG
Sbjct: 18916 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975
Query: 1413 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
P++ +E V E P P V +V T TI E+ SD
Sbjct: 18976 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 19017
Score = 87.0 bits (214), Expect = 2e-16
Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VRAG S + G TW R++ + ++ +++E N ++L+I + G Y
Sbjct: 17731 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17788
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I
Sbjct: 17789 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17847
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
+ +S K + +++ C TSF V++L Y FRV A N +G P + + E
Sbjct: 17848 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17907
Query: 1428 PEEP 1431
P P
Sbjct: 17908 PSPP 17911
Score = 87.0 bits (214), Expect = 2e-16
Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y
Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y +
Sbjct: 18078 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 18137
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
E D+ TW + AT T+ + L EY+FR+ A N YG S P
Sbjct: 18138 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 18185
Score = 85.5 bits (210), Expect = 4e-16
Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472
P F QS V E T F +SG P PEV+WF +G + +++ G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531
+ +SG YS A+N GQ T E L E A P+F L+ V +G
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
LQ V G P P + + +G IQ + + + E + L I +A PED GTY+ A N+
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616
+G+ + +A + V E+ ++K++ ++ A
Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211
Score = 85.5 bits (210), Expect = 4e-16
Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I D G++T A N +G ++V LTVE AVE
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
+ P F KL V +KEG + TG P P + WLK + + P ++ +
Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
G L+I D YT +N +G+ + +++++
Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602
Score = 84.0 bits (206), Expect = 1e-15
Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
+ G + +W K + + VE+S + L + ++ G YT+ ++N G+++
Sbjct: 13701 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
+++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W
Sbjct: 13761 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13820
Query: 1381 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
A+ + T+F V L EY FRV A N YG E
Sbjct: 13821 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13855
Score = 83.6 bits (205), Expect = 2e-15
Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 1237 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
PP+I FP VRAG ++++ ++G T + ++ + E +
Sbjct: 20168 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20227
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
+ + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W
Sbjct: 20228 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20287
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G
Sbjct: 20288 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20347
Query: 1413 SE 1414
S+
Sbjct: 20348 SD 20349
Score = 83.2 bits (204), Expect = 2e-15
Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)
Query: 1238 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
P I++F + +++GES+ + V G TW K +I++ +M++ + +
Sbjct: 21650 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21709
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W
Sbjct: 21710 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21769
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G
Sbjct: 21770 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21829
Query: 1413 SEP 1415
P
Sbjct: 21830 GRP 21832
Score = 82.8 bits (203), Expect = 3e-15
Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)
Query: 882 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938
H EE+ QQ + +++ ++S ++E + PA + + + VKP+ +
Sbjct: 676 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726
Query: 939 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997
SE K + + S + K T V P+ A+P F K +P
Sbjct: 727 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783
Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055
A + K LS + + + + A T+KP AE L A
Sbjct: 784 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840
Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095
+ KS + E+KK+V + GTT E+R E
Sbjct: 841 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894
Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + +
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
I +A ED G + C A N+AG SC V V + E T E + K +
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
+D ++ ++ A P A P I P QK+ G SV +V G W K
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071
Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325
+ KV N + G KL I + G YT++V NK G A +L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 82.4 bits (202), Expect = 4e-15
Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%)
Query: 405 MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457
++G++ + K + +P Q+V E V+ +VS + E W +G V+
Sbjct: 2294 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2352
Query: 458 EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517
+ + + D SH L + D+G YS T L S + +V +V + P
Sbjct: 2353 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2404
Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574
LKD VIEG VL+C V V + W LN + I+ ++ + L I
Sbjct: 2405 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2462
Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
D G Y + +G+V + ++V + K ++GL DL
Sbjct: 2463 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2498
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
+ V V++S + +V+W EI+ S + E G + L + + +D G YT
Sbjct: 2499 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2557
Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753
AGE T LTV ISKP T + Q + C +A +P
Sbjct: 2558 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2605
Query: 754 WLRDGKAL 761
WLRDGK L
Sbjct: 2606 WLRDGKHL 2613
Score = 82.4 bits (202), Expect = 4e-15
Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)
Query: 1086 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
D E R++ + AP K QD+ V GK L + + P A W + L T
Sbjct: 6682 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6741
Query: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
+++ S + +K D+G YK V +N G+AE + V D P
Sbjct: 6742 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6786
Query: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
PV E T + + ++ + G S ++ G V
Sbjct: 6787 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6823
Query: 1265 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322
+ I TW+ + + E + G + + + G + +N + +R
Sbjct: 6824 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6883
Query: 1323 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W
Sbjct: 6884 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6936
Query: 1383 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
T R+ S V D++ EY FRVRA N G +PS + V + E P V ++
Sbjct: 6937 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6996
Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493
D+ + V + + I ER GK + +LV + T KV K
Sbjct: 6997 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 7056
Query: 1494 FFKAYSAKEKENIRQEISIMNCL 1516
+ SA+ K + I+ L
Sbjct: 7057 YLYRVSAENKAGVSDPSEILGPL 7079
Score = 82.4 bits (202), Expect = 4e-15
Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG S + G W K ++ + V+ +++ + LTI A + G Y
Sbjct: 19893 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19950
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I
Sbjct: 19951 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 20009
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E +++ K W + C S+ V +L Y FRV N +G P++ E + EK
Sbjct: 20010 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 20069
Query: 1428 PEEPK 1432
P P+
Sbjct: 20070 PSPPE 20074
Score = 82.4 bits (202), Expect = 4e-15
Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G
Sbjct: 24602 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24661
Query: 662 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
EI + + ++ +G H L I V +D Y A N G V A L V+ P
Sbjct: 24662 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24721
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L
Sbjct: 24722 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24780
Query: 780 VLKK-VQPWHAGQYEILLKNRVG 801
V V+ AG Y + KNR G
Sbjct: 24781 VFPNGVERKDAGFYVVCAKNRFG 24803
Score = 82.0 bits (201), Expect = 5e-15
Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)
Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
R D+M L E P F LP N G +F + +PEP VTW+++GQ I G +
Sbjct: 25374 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25433
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ + +G + L I++V +D +YT A N G +LTV L P
Sbjct: 25434 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25486
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
TL P F L +EGQ F +++G P P + W K
Sbjct: 25487 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25527
Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
PL + + E L I +D G Y N +G S A L ++ L
Sbjct: 25528 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25587
Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
+ F + + V+K++ + L E+
Sbjct: 25588 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25619
Score = 81.6 bits (200), Expect = 6e-15
Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306
V+AG+++ L V G W K + + S +K++ + SK ++ A++ G
Sbjct: 11908 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11967
Query: 1307 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y
Sbjct: 11968 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 12026
Query: 1367 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423
+E ++ W AT + V L+ +EY FRVRA N GT P++ + T
Sbjct: 12027 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 12086
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464
+KP P D EV+ ++E V + + + ++ ++
Sbjct: 12087 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12126
Score = 81.6 bits (200), Expect = 6e-15
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)
Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L
Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24286
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
+ ED G YTC A N GEV T + L +Q P + K + A +G ++ +
Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24344
Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800
G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N
Sbjct: 24345 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24403
Query: 801 GECSCQVSLMLQN 813
G + + +Q+
Sbjct: 24404 GTVDAILDVEIQD 24416
Score = 81.3 bits (199), Expect = 8e-15
Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%)
Query: 416 FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
F + Q KE T+ F CE S P +V W+ +G V + ++ D H+L +
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2187
Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
L T D+ YSC + + + +L V F L+D V E L+
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2241
Query: 535 CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
C V + W N ++ T G L ++D ED G Y+ + +
Sbjct: 2242 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2296
Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
KK++ K + KP LQGLSD KV +G V + V+VS
Sbjct: 2297 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2338
Query: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707
E +W+ +G E+Q S+ H H L I+++ ED G Y+ +++G V
Sbjct: 2339 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2397
Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
+V I+ + V G ++ C ++ +V W + + + K
Sbjct: 2398 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2444
Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
+ + LV+ + G Y++++ RV E +C +S+
Sbjct: 2445 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2484
Score = 80.9 bits (198), Expect = 1e-14
Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+ E ++ F E+S P W L+G + R + E+ + G +L L K + +G
Sbjct: 5103 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 5160
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
A NA + L V E+ F+ LKD V E + +C + T
Sbjct: 5161 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 5209
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601
+ W I+ + + HI D+ +D G YT E + S +VT
Sbjct: 5210 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 5267
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
K F+ L D V +G T ++S + V+W N
Sbjct: 5268 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 5306
Query: 662 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
++ S G H L ++EV +D + E+ + A L V E P
Sbjct: 5307 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 5358
Query: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
+F K TA + + C ++ D V W +DG+ + + + + L +
Sbjct: 5359 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 5415
Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837
KK G+Y C C N + A L + +P ++ G
Sbjct: 5416 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 5466
Query: 838 ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889
+ D +G W +GQ D E + K + T + + +A
Sbjct: 5467 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 5522
Query: 890 QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949
+ L ++L + LS D+K ++ F + R+ PKT R + Q
Sbjct: 5523 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 5572
Query: 950 QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007
++ D R L K GT + V + A F + + +G E + K
Sbjct: 5573 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 5626
Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067
+ K ++ + + V + +K N + T + + + + + S + ++L
Sbjct: 5627 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 5685
Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
D + + + G + K + +G P F KLQD E +++LQC++S A
Sbjct: 5686 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 5741
Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ W +GK +K +K ++ +G + ++KAL D G Y C D G + S ++ +
Sbjct: 5742 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5797
Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
+D E+K RP S+ V+ TE+
Sbjct: 5798 EDR---------EIKLVRPLHSV-EVMETET 5818
Score = 80.9 bits (198), Expect = 1e-14
Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PPKA + ++ + +RAG + L V G W K K++ E + ++ +
Sbjct: 22738 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22795
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ I + G YTL V+N G++ V + V+D P P G S + TL
Sbjct: 22796 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22854
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N
Sbjct: 22855 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22914
Query: 1410 YG-----TSEPSQESELTTVGEKPEEPKD 1433
YG SEP T+ P P++
Sbjct: 22915 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22943
Score = 79.7 bits (195), Expect = 2e-14
Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
+AG+++++ V G T TW K + +++++ + E + + L I + G Y
Sbjct: 14773 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14832
Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
L N +G + + V D P PP G ++ S +T SW DGG + +Y +E
Sbjct: 14833 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14892
Query: 1370 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411
+ + + TW ELA T T++ L EY+FRV+A N YG
Sbjct: 14893 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14935
Score = 79.3 bits (194), Expect = 3e-14
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 1738 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1797
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284
Query: 1798 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 79.3 bits (194), Expect = 3e-14
Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%)
Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R
Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079
Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
LVI V ED +A N +G L V+ AKQL
Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127
Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199
F +L VV KE M F C+ T P +V W K +
Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
+ + + + L I ++ D Y+C++V +A+L ++G A
Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2222
Query: 260 FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
FV+E + E+ ++S E+ + +E + K + +RG +
Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282
Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363
+ E K +CK + P +LQ S + VQ E + GV
Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341
Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420
G+E +P+ + L +D+ + A IP G S S
Sbjct: 2342 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400
Query: 421 QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
+K+ ++ C+VS V W+L + + + ++ L +
Sbjct: 2401 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2459
Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
+ D G Y G++ + L VE++ ++ L+D E Q+ V +
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2508
Query: 536 SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
+ + + + W + I+ + + + +L + + + +D G YT A G+
Sbjct: 2509 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2563
Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
S +TV A SKP L+D V + + +V+ NP
Sbjct: 2564 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2602
Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+ WL +G + + + E G + L I +D G YT + S +T A L V
Sbjct: 2603 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2658
Query: 713 QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
+ I K +++T + Q + + + V W+++G L
Sbjct: 2659 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701
Score = 79.0 bits (193), Expect = 4e-14
Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471
P+F ++ + V+F ++ P+P V W+ G ++ + + D G +
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25444
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528
L + T D Y+ A N G+ SC L V + P F +L + EG
Sbjct: 25445 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 25504
Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584
Q + V G P P + W +GQP+ + G+ LHI+D LPED G Y
Sbjct: 25505 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 25564
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEY 611
A N G SC A + V E+ +K E+
Sbjct: 25565 ATNTAGSTSCQAHLQV-ERLRYKKQEF 25590
Score = 78.6 bits (192), Expect = 5e-14
Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)
Query: 1225 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276
+P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K
Sbjct: 8359 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8416
Query: 1277 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310
++QE E + ++NS+ G S+L + + + G Y +
Sbjct: 8417 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8476
Query: 1311 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370
VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E
Sbjct: 8477 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8535
Query: 1371 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
D + W + +T R ++V L+ EY FRVRA N +G P L V +
Sbjct: 8536 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8593
Query: 1428 PEEPKD 1433
P P D
Sbjct: 8594 PFGPPD 8599
Score = 78.2 bits (191), Expect = 7e-14
Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%)
Query: 36 ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94
I P +++ + EG A E +V V W+ N + I R + ++GT LVI+
Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2459
Query: 95 AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154
H D G Y G + L+VE
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2487
Query: 155 IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214
K L + E Q F +++ V W + ++PS++ +
Sbjct: 2488 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2539
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272
+ L + + +DD G YT +G+ S +L++ G + ++ +T A + +
Sbjct: 2540 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2594
Query: 273 KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329
EV N SK L + + N S G A K+ + K S
Sbjct: 2595 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2654
Query: 330 RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378
+ + ++KT ++T+ + P G+ GV+ S E+
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2714
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
+ + + + V R + + K KP+ EN TV F VS
Sbjct: 2715 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2773
Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
P V WF + ++ + + + H L L D+G Y+ GQL C
Sbjct: 2774 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2827
Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
L VE L + + +K+ V E + +C V VP + WL NG I+ +
Sbjct: 2828 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2879
Query: 559 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
+ + +L I + ED YT + N QVS + VT
Sbjct: 2880 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2921
Query: 616 APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674
PI + L D+ + +T V V+ WL NG EI+ ++ +
Sbjct: 2922 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 2973
Query: 675 GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
HSL I+ V D YT AG+ + A L V+ H F + +
Sbjct: 2974 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3025
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
+ + C ++ +P TV W++D + L + T ++ + + V L++ + AG+Y +
Sbjct: 3026 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083
Query: 795 LLKNRV 800
+ V
Sbjct: 3084 VAGGNV 3089
Score = 78.2 bits (191), Expect = 7e-14
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)
Query: 1228 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
P T A + P + F + +V + + TG T TW K ++ + +K
Sbjct: 7078 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7137
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI
Sbjct: 7138 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7196
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404
S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V
Sbjct: 7197 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7256
Query: 1405 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433
A N G EP+ E ++T P+ P++
Sbjct: 7257 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7288
Score = 78.2 bits (191), Expect = 7e-14
Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
PA ++L V ++ +L + D + I L K + F + + + ++
Sbjct: 22241 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22300
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
E+ + + ++ AKNDAG +E P+ + V+
Sbjct: 22301 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22332
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+K+ T + Q+I +AG + ++G TW +
Sbjct: 22333 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22382
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G
Sbjct: 22383 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22442
Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396
S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L
Sbjct: 22443 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22502
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
EY FRV + N +G S+P + + + + E P P
Sbjct: 22503 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22535
Score = 77.4 bits (189), Expect = 1e-13
Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%)
Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
S+DVV + G + A P F +KP Q++ E +V F C+V G PKP V W
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072
Query: 451 GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509
G P+ + + G L + D+G Y+ N G+ S S +L +E
Sbjct: 1073 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567
+ S +L V FV + V G P + + + ++ +A+
Sbjct: 1132 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625
+ ++ + + + E + ++ T E+ + + + + ++ S+ F
Sbjct: 1188 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1247
Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683
+ + ++++G VT ++SG P P++ W +G I+ E + F Q G + SL I
Sbjct: 1248 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1306
Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732
V PED G YT A N G L V+ P +I PRSV+
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366
Query: 733 S 733
S
Sbjct: 1367 S 1367
Score = 77.0 bits (188), Expect = 2e-13
Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI
Sbjct: 16925 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16984
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++ +D G Y N GQ S ++ D P + K P
Sbjct: 16985 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 17027
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
D + + PP QI + ++ T W
Sbjct: 17028 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 17071
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332
+ + +KV + G++ + + EN+ G A + +V +P
Sbjct: 17072 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 17119
Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385
PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT
Sbjct: 17120 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 17173
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
T F Q+L EY+FRV A N+ G + S+ SE + + P
Sbjct: 17174 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17219
Score = 76.6 bits (187), Expect = 2e-13
Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+
Sbjct: 6520 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6578
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206
+D Y C ++ +A + + V+ +AP ++ E+ +
Sbjct: 6579 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6638
Query: 1207 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241
++++ V G + + K + + A P+I
Sbjct: 6639 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6698
Query: 1242 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301
+D V G+ + + W K + + ++ + + IL A+
Sbjct: 6699 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6755
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+ G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS
Sbjct: 6756 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6814
Query: 1362 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418
+ Y +E D KTW LAT R+ S F V L EY FRV A N GT EP +
Sbjct: 6815 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6873
Query: 1419 SELTTVGEKPEEPKDEVEVSDDD 1441
K + P + V+ D
Sbjct: 6874 DNPVEARSKYDVPGPPLNVTITD 6896
Score = 76.3 bits (186), Expect = 3e-13
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 1721 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1779
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918
Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977
Query: 1840 ATCTAELIVETMEEGEGE 1857
+ + L V+ EE E E
Sbjct: 978 VSTSCYLAVQVSEEFEKE 995
Score = 75.9 bits (185), Expect = 3e-13
Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%)
Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678
K P+ L D +G V +T ++ EV W + E F Q +
Sbjct: 4431 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4488
Query: 679 SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737
+L I +V ED G Y CEA N +G+ T A LTV + P K + +LG
Sbjct: 4489 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4545
Query: 738 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797
+C I P W + G+ + ++ + ++ + +L + + Q G+Y
Sbjct: 4546 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4604
Query: 798 NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
N G SC +L + R L R+P E++ S+
Sbjct: 4605 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4651
Query: 854 PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 913
P + +E + E V K+ + + + EV + R+ +K+ T +
Sbjct: 4652 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4704
Query: 914 DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 970
IP + + + +V KP V E + +P V V+ KK +K P E
Sbjct: 4705 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4761
Query: 971 VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 1027
P P + G KK P+ + + E P + + PLK V
Sbjct: 4762 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4814
Query: 1028 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1073
K + +G++ E L A K N++ + K D K+
Sbjct: 4815 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4874
Query: 1074 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1124
+ C + G+ T K + K ++V V +G+ L L C+++ +
Sbjct: 4875 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4934
Query: 1125 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1183
++W +GK ++ I+ G + +++I A D G Y +N A ECS
Sbjct: 4935 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4991
Query: 1184 QVTV 1187
V V
Sbjct: 4992 CVKV 4995
Score = 75.9 bits (185), Expect = 3e-13
Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)
Query: 1052 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105
N++P ++LK +E + D + + + +A G ++ + SE+ P +
Sbjct: 8030 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 8089
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D
Sbjct: 8090 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8149
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
G+Y +N G A S V V P ++K+ SD T
Sbjct: 8150 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 8191
Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
PP+ G PI ++ R++ ++
Sbjct: 8192 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8223
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343
V + EN T+ + + NK+G + N + P P P ++
Sbjct: 8224 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8283
Query: 1344 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395
+ ++T++W YDGGS + Y IE + WK C ++ + L
Sbjct: 8284 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8340
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442
EY+FRVRA N G SEPS+ + T + + PK +EV DE
Sbjct: 8341 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8391
Score = 73.9 bits (180), Expect = 1e-12
Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
VKE Q V F CEV+ + WF + I + +D + L + A D
Sbjct: 6346 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 6403
Query: 485 YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
Y+ + +N +G+ + + L VE + V P LKD +E + C V V
Sbjct: 6404 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 6458
Query: 544 RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
+ W NG+ + + H I+D D G Y VT
Sbjct: 6459 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 6502
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
+ KS +E L+ AP++ F++ L D V + + Q+S V W NG
Sbjct: 6503 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 6554
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719
EI+E + + FE+ G+ H L I++ +D Y C + +++A L V+E P +
Sbjct: 6555 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 6610
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
+P P+ + + G V+ + D V WLR+ + + H +++ + L
Sbjct: 6611 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 6663
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVS 808
+ ++P G+Y + K++ +++
Sbjct: 6664 QICDIKPRDQGEYRFIAKDKEARAKLELA 6692
Score = 73.9 bits (180), Expect = 1e-12
Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V+V G L + +S P + + +G LK T ++++++++ D G
Sbjct: 20181 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20240
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224
Y+ A N +G + + V D P P V+ TE T+K
Sbjct: 20241 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20286
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+P PK + + I+ ++ S ++ +V+ T + T MK K E+
Sbjct: 20287 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20336
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344
+EN + + + S V L P PP+ TP +++
Sbjct: 20337 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20377
Query: 1345 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402
S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F
Sbjct: 20378 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20437
Query: 1403 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
RV A N G +PS SE + E P++ V ++D + + ++ + K++
Sbjct: 20438 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20496
Query: 1463 FYDIEER 1469
Y +E R
Sbjct: 20497 -YIVERR 20502
Score = 73.6 bits (179), Expect = 2e-12
Identities = 33/91 (36%), Positives = 56/91 (61%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328
R+++ ++ +++ G+ L + ++ + + EN+ G S + T +
Sbjct: 23962 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 24021
Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386
+ P+PP+ P D+ SS++LSW DGGS V Y IE +++ W +
Sbjct: 24022 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 24081
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437
T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+
Sbjct: 24082 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 24134
Score = 72.4 bits (176), Expect = 4e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)
Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++
Sbjct: 8793 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8848
Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347
N S+L I A ++ G Y + N GS+ A + V D P P R
Sbjct: 8849 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8908
Query: 1348 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407
L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A
Sbjct: 8909 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8967
Query: 1408 NVYGTSEPSQESELTTV 1424
N +G P + + V
Sbjct: 8968 NKFGCGPPVEIGPILAV 8984
Score = 71.6 bits (174), Expect = 7e-12
Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
+D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T
Sbjct: 20859 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20917
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+
Sbjct: 20918 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20971
Score = 71.2 bits (173), Expect = 9e-12
Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324
P T W++ K + +V+ N K + +L EN G + +
Sbjct: 7619 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7667
Query: 1325 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
+ + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W
Sbjct: 7668 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7727
Query: 1381 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437
+A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV
Sbjct: 7728 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7787
Score = 70.9 bits (172), Expect = 1e-11
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P
Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538
Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P + W +N I + ++ G +G +L I + +D YT A N +G
Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597
Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
++ VE FA+ + + G +AP +E +G + P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657
Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
F KL + +K F C++T G P V WL PL+ + R+ + + G L+
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
D G+ TC N G SA L ++ +S V E++
Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759
Score = 70.9 bits (172), Expect = 1e-11
Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%)
Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
SE +GT P F +++ + ++ G L V P I W NG L + +G
Sbjct: 3642 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3701
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
S+ I ED G Y C+A ND G+ CS + + N+K K
Sbjct: 3702 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3747
Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
TE+++ V K P PP ++ + + G V G T T
Sbjct: 3748 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3799
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329
W K KQ+ S + + ++ NGS I+ ++E G Y EN LG L V+
Sbjct: 3800 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3859
Query: 1330 KPDPPAGTPC 1339
+ TPC
Sbjct: 3860 EDTDMTDTPC 3869
Score = 70.9 bits (172), Expect = 1e-11
Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G
Sbjct: 21268 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21327
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y + N C++ V P + T P K + P
Sbjct: 21328 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21358
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283
I+F E + +SV L V G ITC ++ R+ Q +
Sbjct: 21359 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21400
Query: 1284 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337
M + + K+ L E+ + + EN+ G Q V+ +V K P PP G
Sbjct: 21401 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21457
Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395
P ++ S ++L+W YDGGS V + +E + + W+++ T + L+
Sbjct: 21458 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21517
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455
+Y+FRV A N G S PS S+ T+ P +P + D V T+T+
Sbjct: 21518 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21569
Query: 1456 TEQKVSD------FYDIEERLGSGKF 1475
+ D Y IE+R G+ ++
Sbjct: 21570 WNPPLRDGGSKIVGYSIEKRQGNERW 21595
Score = 70.5 bits (171), Expect = 1e-11
Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A + I+ L+V +D F +P +++ + E A+FE + E
Sbjct: 5159 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5207
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W + I S +F + + LVI+ +D G YT E
Sbjct: 5208 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5252
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
VEG K R + KF + L VKEG+ F
Sbjct: 5253 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5289
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C+++ + V W K + L S V +S + LE+ V DD+ V +
Sbjct: 5290 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 5344
Query: 242 ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283
S +A+L + D + + A D V K+V K+
Sbjct: 5345 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 5404
Query: 284 KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337
K D L K K +G G+ AN + R K+E P + V
Sbjct: 5405 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 5459
Query: 338 LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397
+ I L V + + G + + E Q G+ + +V +
Sbjct: 5460 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 5518
Query: 398 AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456
AAN + + P P S +V E KF CEVS PK W L+GT
Sbjct: 5519 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 5575
Query: 457 QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516
+ E+ +D H + + A D Y A + +L + + F
Sbjct: 5576 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 5626
Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576
+ LKD E + V + + R+ W N Q + RS + +QD
Sbjct: 5627 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 5677
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
T+ L+ + Q+ A SE L V P F L D ++
Sbjct: 5678 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 5726
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
+V + ++S P V W +G EI+ S++ + G + L +++ D G YTC+
Sbjct: 5727 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 5785
Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
G +T L +++ + + SV ++ I+ D +W
Sbjct: 5786 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 5836
Query: 757 DGKALCKDTGHFEVLQNEDVFTLVL 781
G+AL + T E+ + + +LVL
Sbjct: 5837 KGEALLQ-TPDCEIKEEGKIHSLVL 5860
Score = 70.5 bits (171), Expect = 1e-11
Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L + V G K+ L V+ P I WT LK K I + +V+I +
Sbjct: 7392 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7451
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y A N G+A +V V D P PP +D T +
Sbjct: 7452 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7493
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
PP+ +I + +++ E W K ++++
Sbjct: 7494 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7537
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339
K T L +E+ + + EN G Q + +T + DPP G P
Sbjct: 7538 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7584
Query: 1340 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396
SDI ++TL+W DGGS + Y +E D W + T++ V+ L
Sbjct: 7585 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7644
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
+Y+FRV A N+ G +PS+ +E + + + P
Sbjct: 7645 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7679
Score = 70.1 bits (170), Expect = 2e-11
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1815
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 69.3 bits (168), Expect = 3e-11
Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)
Query: 1217 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
ESD V + P P TP A+ + + V G S + + + + W
Sbjct: 17105 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 17164
Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
K K I K +N E G + + + EN +G +A N
Sbjct: 17165 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17213
Query: 1332 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387
DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T
Sbjct: 17214 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17273
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438
F V L D Y+FRV A N G S+PS + T ++ E P +D + V+
Sbjct: 17274 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17333
Query: 1439 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495
+ E D + T + + +IEE F+ L+ K ++ G++
Sbjct: 17334 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17393
Query: 1496 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554
+A + ++ + +++ P+ VQ EK ++ + GG + E
Sbjct: 17394 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17453
Query: 1555 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598
E + E + +++ EG EY+ + IM VNK G
Sbjct: 17454 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17495
Score = 69.3 bits (168), Expect = 3e-11
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Query: 1306 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357
GC Y + EN G ++ DP P P D +++T++W +
Sbjct: 19745 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19804
Query: 1358 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS
Sbjct: 19805 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19864
Query: 1417 QESELTTVGEKPEEPKDEVE 1436
S+ E+ EEP +++
Sbjct: 19865 DSSDPQIAKEREEEPLFDID 19884
Score = 69.3 bits (168), Expect = 3e-11
Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%)
Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
E S ++EVT + E + + + A + + S+ + R SP +
Sbjct: 25924 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25983
Query: 311 --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368
S+PQP E + ++ + SP TP + PR+P SP
Sbjct: 25984 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 26018
Query: 369 EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423
ER R A F +R + + K + R+ + Q+ P+ + +S
Sbjct: 26019 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 26078
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
V Q +F V P EV W+ G ++ + I +G L +L T DSG
Sbjct: 26079 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 26137
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542
TY +N +G+ S TL V G D+ S R V
Sbjct: 26138 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 26175
Query: 543 PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
PR + + YA S+ EA + ++ + E + + +A ++ +A
Sbjct: 26176 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 26235
Query: 597 WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
++ EK ++RK + L A L + V +G + G P P V
Sbjct: 26236 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26287
Query: 655 IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714
WL G + S + + I V D G Y+ NS G+ + LT+Q+
Sbjct: 26288 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 26347
Score = 69.3 bits (168), Expect = 3e-11
Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L AP L R+ + G +F V+ P +V W+ NG + + G
Sbjct: 26065 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 26123
Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
+L I H +D G Y T + T G R V EL
Sbjct: 26124 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 26183
Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
T ++A K+ + S ++ + + ETR S+
Sbjct: 26184 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26242
Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
+ TK + V EG+ RFSC G P P VTWL+ L SAR
Sbjct: 26243 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26302
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
V+ EI V D G Y+ +V N GK L+IQ ++ V E KA
Sbjct: 26303 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26355
Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
S R V S E ++ S EA K SP+ P P + + E +
Sbjct: 26356 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26406
Query: 328 SPRTAP 333
P +AP
Sbjct: 26407 LPVSAP 26412
Score = 68.9 bits (167), Expect = 4e-11
Identities = 55/191 (28%), Positives = 77/191 (40%), Gaps = 11/191 (5%)
Query: 444 EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTASNAQGQLSCSWTL 502
EV W+ E V E + +D ++ L + K T D G Y C A N G+ + S L
Sbjct: 4463 EVNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4521
Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE 562
V V AP ++ V G C ++ P R W G+ I Y C
Sbjct: 4522 TV----VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCS 4576
Query: 563 AG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
++ L I D G YTC A N G VSC+A +TV +K LLP
Sbjct: 4577 IRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKP 4636
Query: 619 KPTAPIFLQGL 629
+P + L+ +
Sbjct: 4637 EPKEEVVLKSV 4647
Score = 68.9 bits (167), Expect = 4e-11
Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)
Query: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
P KL V V G + L+ V P + WT + T+ + +
Sbjct: 11896 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11955
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213
S+ KA D G Y A N AG V V D P N K ++ S R
Sbjct: 11956 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 12007
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
TV P P+ + I++ E +++ W
Sbjct: 12008 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 12040
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330
+ + G+ +T L E+ + + ENK+G+ + V+ K
Sbjct: 12041 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 12088
Query: 1331 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
PDPP T + + +T+ W YDGG ++ Y +E + + W + +
Sbjct: 12089 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 12144
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
VQ+LLPDHEY+FRV+A N G EPS S V + P EP
Sbjct: 12145 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 12191
Score = 68.6 bits (166), Expect = 6e-11
Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI
Sbjct: 19090 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 19149
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++A ED G Y+ N AG + V D P PP
Sbjct: 19150 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 19191
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+ + PP+ QI + ++K + + TW +
Sbjct: 19192 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19235
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333
+ + +K+ GS+ + + EN+ G + VV + P
Sbjct: 19236 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19283
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386
P GTP S++ ++W DGGS V Y +E +W ANK
Sbjct: 19284 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19338
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446
T V L Y++RV A N+ G + S+ E P +P + EV++ K
Sbjct: 19339 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19397
Query: 1447 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475
+ + + K++ + L G++
Sbjct: 19398 LKWSKPHYDGGAKITGYIVERRELPDGRW 19426
Score = 68.6 bits (166), Expect = 6e-11
Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)
Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+
Sbjct: 26822 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26881
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194
++ S+ I A D G Y AKN GQ + + V + P+ E
Sbjct: 26882 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26941
Query: 1195 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235
++++ +M + + ++S + + + + K A + +
Sbjct: 26942 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 27001
Query: 1236 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
+PP+I P D + G+ + + TG TW
Sbjct: 27002 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 27061
Query: 1276 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ +
Sbjct: 27062 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115
Score = 68.2 bits (165), Expect = 7e-11
Identities = 86/356 (24%), Positives = 138/356 (38%), Gaps = 82/356 (23%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154
P Q+LQ V V GK +S P I W + L T KF+ QE +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
+ +A PED +Y C AKND G A S ++V+ PE+ S P +P
Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
PP II +D G+ +V+GT + +W
Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV-VDKPDP 1333
K+I+ S ++ E+ +L I A E G YT + N +G + NL++ V D
Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDR 3394
Query: 1334 PAGTPCASDIRSSSLT--------------------LSWYGSSYDGGSAVQSYSIEIWDS 1373
+ D+R S+ + S+ GSSY+ Y +++++S
Sbjct: 3395 QSS---GKDVRESAKSQAVADSSFTKEESKISQKEIKSFQGSSYE-------YEVQVFES 3444
Query: 1374 ANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429
++ + T+ +VQD H + ++E S+E + GE P+
Sbjct: 3445 VSQ------SSIHTAASVQDTQLCHTASLS----QIAESTELSKECAKESTGEAPK 3490
Score = 67.4 bits (163), Expect = 1e-10
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 1737 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 67.0 bits (162), Expect = 2e-10
Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
++ + V G + + P T WT +G +KT + + + ++I+ L
Sbjct: 11212 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11271
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y+ N AG + +TV D P P + + T T+
Sbjct: 11272 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11319
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
+P P P I E Q R + +G V+
Sbjct: 11320 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11350
Query: 1284 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336
+GS T L GC + + ENK+G + V K P P G
Sbjct: 11351 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11403
Query: 1337 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390
P +DI ++ T+SW DGGS + Y +E W NKT F
Sbjct: 11404 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11458
Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
V L + Y+FRV A N+ G S+PS S+
Sbjct: 11459 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11488
Score = 67.0 bits (162), Expect = 2e-10
Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 13061
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224
A+N +G + ++ V D P + K +M S R S P L G+E +
Sbjct: 13062 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 13121
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
K P A +V+ T PIT ++ K I+ E+
Sbjct: 13122 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 13154
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340
+ + ENK G + K DPP P
Sbjct: 13155 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 13191
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
S+I +T+SW + DGGS + Y +E ++ W ++ + L
Sbjct: 13192 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13251
Query: 1399 EYKFRVRAINVYGTSEPSQESE 1420
EY+FRV AIN G +PS S+
Sbjct: 13252 EYEFRVTAINKAGPGKPSDASK 13273
Score = 66.6 bits (161), Expect = 2e-10
Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)
Query: 1083 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134
G +D S+ Q ++ L D+ K L+++ S P ++W+
Sbjct: 19859 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19918
Query: 1135 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
L+T ++ + S S++IE A D G Y +N A + V V D P
Sbjct: 19919 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19974
Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254
PP T D T + A + + PE+
Sbjct: 19975 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19999
Query: 1255 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312
G P+ ++ R + S+ V + N ++L+ + Y V
Sbjct: 20000 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 20048
Query: 1313 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E
Sbjct: 20049 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 20107
Query: 1370 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429
+ K W + A +ST V L + EY FRV A N G S+P + + E+ E
Sbjct: 20108 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 20167
Query: 1430 EPKDEVE 1436
P+ +++
Sbjct: 20168 PPEIDMK 20174
Score = 65.9 bits (159), Expect = 4e-10
Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8867
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y A N G + +V V D P P L PV+ T +
Sbjct: 8868 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8913
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
P+ + + II+ +D K+ T QPI E+E K
Sbjct: 8914 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8949
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342
+ +T L QE+ + ++ +NK G ++ + VD PP ++
Sbjct: 8950 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 9000
Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400
S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y
Sbjct: 9001 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 9060
Query: 1401 KFRVRAINVYGTSEPS 1416
+FRV+A+N G SEPS
Sbjct: 9061 EFRVKAVNEIGESEPS 9076
Score = 65.9 bits (159), Expect = 4e-10
Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15230
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A N G A+ V V D P P V S+ V P
Sbjct: 15231 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15277
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
A + I+Q E ++ W ++Q ++
Sbjct: 15278 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15308
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346
K+T L E+ + ++ NK G + + V+ PDPP P + I
Sbjct: 15309 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15364
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+
Sbjct: 15365 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15424
Query: 1405 RAINVYGTSEPSQES 1419
A N G S PS S
Sbjct: 15425 MAENAAGISAPSPTS 15439
Score = 65.9 bits (159), Expect = 4e-10
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW +
Sbjct: 15711 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15769
Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q
Sbjct: 15770 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15829
Query: 1418 ES 1419
S
Sbjct: 15830 LS 15831
Score = 65.9 bits (159), Expect = 4e-10
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T
Sbjct: 23037 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 23095
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K
Sbjct: 23096 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 23149
Score = 65.5 bits (158), Expect = 5e-10
Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
+AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G
Sbjct: 24621 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24680
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
L+I +V ++D Y ATN G+ T L VE L
Sbjct: 24681 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24722
Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
PK +G V G++ +G+P P +TW KG + + V
Sbjct: 24723 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24771
Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
L +GV + D G Y N G + EL + + R
Sbjct: 24772 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24825
Query: 269 SDVRKEVTNVISKESKLD 286
SDV ++ N+ E D
Sbjct: 24826 SDVSRDSVNLTWTEPASD 24843
Score = 64.7 bits (156), Expect = 8e-10
Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+ K + G+ L ++ V P I W +G+ LK T + + + + + I
Sbjct: 18007 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 18066
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++ +D G Y A N AG A + V V + P PPV
Sbjct: 18067 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 18108
Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
D + PP QI + +++ T TW
Sbjct: 18109 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 18152
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331
+ + +K+ + G++ + + EN+ G + V+ +P
Sbjct: 18153 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18200
Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389
PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F
Sbjct: 18201 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18259
Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
L EY+F+V A N+ G +PS+ SE + + P
Sbjct: 18260 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18301
Score = 64.7 bits (156), Expect = 8e-10
Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)
Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R
Sbjct: 26233 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26291
Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
GQ +++ R + + TF I +V D G Y+ N G ++ LT++ +
Sbjct: 26292 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26349
Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
K + P K+ R +P ET+P+ +
Sbjct: 26350 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26409
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
PPK L KE + + +C + +VTW K L+ + +G
Sbjct: 26410 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26467
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
L+I+ + + D G Y C + G + + + Q S + + ++ SD +
Sbjct: 26468 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26527
Query: 275 VTNVISK 281
+ V K
Sbjct: 26528 ESTVTRK 26534
Score = 64.3 bits (155), Expect = 1e-09
Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VR G+++ + +V G TW K K + + + + +L I A + G Y
Sbjct: 11615 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11674
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ +N G Q + V+D+P P +++ + T+SW +GGS + ++ +
Sbjct: 11675 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11733
Query: 1369 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425
E K W +A+ + +LL ++EY FRV A N G P+ E++ +
Sbjct: 11734 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11792
Query: 1426 -EKPEEPKD 1433
++P EP++
Sbjct: 11793 IDRPGEPEN 11801
Score = 64.3 bits (155), Expect = 1e-09
Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)
Query: 1215 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269
G +S+ V + P P PP PP I+ D SV L K TG PIT
Sbjct: 13856 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13904
Query: 1270 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
++F R + K K+T L E+ + ++ N G + +
Sbjct: 13905 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13962
Query: 1328 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
V DP P G P +I +S+TL W YDGG + Y +E D +K+W +
Sbjct: 13963 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 14022
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431
+F V DL+ +Y+FR+RA N G S PS+ +E ++ E P
Sbjct: 14023 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14071
Score = 63.9 bits (154), Expect = 1e-09
Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
QE C Y + EN+ G Q + V + P PP G D+ +S++LSW +
Sbjct: 16793 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16851
Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P
Sbjct: 16852 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16909
Score = 63.5 bits (153), Expect = 2e-09
Identities = 95/427 (22%), Positives = 150/427 (35%), Gaps = 53/427 (12%)
Query: 1088 EKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILS 1147
E ES G AP LQDV V G C + D + WT G ++ ++ + S
Sbjct: 3479 ECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQS 3538
Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS------ENTKAPEM 1201
Q G++ ++I D+GLY C+ ND G+ S ++V+ AP S E EM
Sbjct: 3539 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEIEMEM 3598
Query: 1202 K----------------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPE 1245
K + S + L S++ V P K P I+
Sbjct: 3599 KEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEVS 3656
Query: 1246 DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHC 1305
+ + G+ L V G W + S K + L IL + E
Sbjct: 3657 NADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDE 3716
Query: 1306 GCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY-------- 1357
G YT + N G L + K + T S + S L +
Sbjct: 3717 GEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPI 3776
Query: 1358 ---DGGSAVQSYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHEY 1400
G A+ Y++ + TW K+L T S +F V D +
Sbjct: 3777 RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 3836
Query: 1401 KFRVRAINVYGTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINT 1456
+ +A N+ G S + E E T + + P + K E +D + P +++
Sbjct: 3837 LYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDS 3896
Query: 1457 EQKVSDF 1463
EQ+++ F
Sbjct: 3897 EQEIATF 3903
Score = 63.5 bits (153), Expect = 2e-09
Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271
S+ TV + P K P P + + +V+ E + G +V G + + W
Sbjct: 16024 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 16082
Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+K K K E G + + + G +G V P
Sbjct: 16083 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 16133
Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389
P G P A + +S+TL W +YDGGS + Y +E + W + + T F
Sbjct: 16134 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16193
Query: 1390 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432
V L+ DH Y+FRV A N G SEPS+ + T ++ + P+
Sbjct: 16194 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16237
Score = 63.5 bits (153), Expect = 2e-09
Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+
Sbjct: 20582 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20641
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
+N G A + +V + D P P + T T+ +P P
Sbjct: 20642 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20688
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
A + I++ E +V W SEH++ E
Sbjct: 20689 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20718
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
T + E+ + + NK G + + +VV K P PP G P + I +
Sbjct: 20719 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20775
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404
S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV
Sbjct: 20776 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20835
Query: 1405 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439
A+N G S+ SE + P P ++ ++D
Sbjct: 20836 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20872
Score = 63.2 bits (152), Expect = 2e-09
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383
P P P D SS++L W + DGGS ++ Y +E+ + WK + T
Sbjct: 9399 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9458
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D
Sbjct: 9459 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9513
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383
+ KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ +
Sbjct: 10805 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10863
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432
C T + V L YKFRV A+N G S+P+ E V ++ E P+
Sbjct: 10864 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10912
Score = 63.2 bits (152), Expect = 2e-09
Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)
Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063
K V +S PLS P L+ K + TL L P+ G AK D + S
Sbjct: 12483 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12533
Query: 1064 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104
+EE D + + + + G + +K E++G A +Q L
Sbjct: 12534 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12593
Query: 1105 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
+ + + GKKL ++ V P T W + T+ + + + S + I
Sbjct: 12594 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12653
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215
+ +D G Y A+N +G +V V DAP PP +
Sbjct: 12654 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12698
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
++DA P + + I+ E V G+ V VT T +
Sbjct: 12699 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12749
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
K I E++ +EN G L K+ AQ V +P
Sbjct: 12750 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12794
Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388
T D + ++W DGGS + Y IE +W AN T RST
Sbjct: 12795 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12845
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
+ L+ EY FR+ A+N G+S PS+ +E T P +P + EV D
Sbjct: 12846 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12895
Score = 63.2 bits (152), Expect = 2e-09
Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)
Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G
Sbjct: 25275 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25333
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C+ N G EL V+G +++ +T+ + +T + E PP+F
Sbjct: 25334 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25387
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
L G+ RF IT P+P VTW K ++P + + G+ L I
Sbjct: 25388 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25447
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ V DD YT + N G+ S A+L++
Sbjct: 25448 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 62.8 bits (151), Expect = 3e-09
Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)
Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143
D EK+ + P FK+KL + + +C+++ DP + W +GK L+
Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704
Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203
+ + E CS+ A D G+ C A N G S + V D E + E +
Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760
Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263
+ L + E A T K P I+ +PE +V GE+ +VTG
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323
W + I++S+ +V + L I+ + G + EN G + +V
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879
Query: 1324 NLTVVDKPD 1332
L + + D
Sbjct: 1880 KLEIQQRED 1888
Score = 62.8 bits (151), Expect = 3e-09
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386
KP PP P DI SS+ LSW YDGG +Q Y +E D + W
Sbjct: 16532 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16590
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
T+ V+ LL HEY FR+ AIN G E + V EK E P ++++
Sbjct: 16591 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16641
Score = 62.4 bits (150), Expect = 4e-09
Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G
Sbjct: 14481 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14538
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
+ + N +GK S ++++ LD+ +R T T V +TN
Sbjct: 14539 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14596
Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
I ++ ++ A K C+ G S A N +P ++
Sbjct: 14597 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14656
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
++P ++ T S+++L P+P+ G ++ E +R + T T
Sbjct: 14657 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 14711
Query: 386 QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425
GL Q + +A R P E + + P+ + + Q++
Sbjct: 14712 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14771
Query: 426 -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
K +K V G PKP V W +G + +Q + A S L + + DSG
Sbjct: 14772 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 14830
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522
Y TA N G++ T+QV + P F V D
Sbjct: 14831 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 14869
Score = 62.4 bits (150), Expect = 4e-09
Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569
AP +KD G+ L C + G P+P I W G+ + +R + + L
Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24286
Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628
+ ED G YTC+A N +G+V S S+ LL P P P+ +
Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24333
Query: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
+ GS + + V G P P + W H +Q SE+ E L ++ V +
Sbjct: 24334 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24389
Query: 689 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
G Y + N G V A+L V+ +P + P + A L S +IS
Sbjct: 24390 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24438
Score = 62.0 bits (149), Expect = 5e-09
Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I +D G +TC VN +G S S L++Q + F +ET A VT
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003
Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
+ E K ++S + + + Q G P A
Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035
Score = 62.0 bits (149), Expect = 5e-09
Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329
+++ + V + TI + H + ++ +NK G + + +
Sbjct: 9951 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 10010
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383
P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A
Sbjct: 10011 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 10069
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
S+ V L+ +Y+FRV AIN G S S+ T + P
Sbjct: 10070 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 10117
Score = 62.0 bits (149), Expect = 5e-09
Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y AKN +G A+ S V V D P P +L T+ + T+
Sbjct: 11673 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11716
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
+ P D G IT +++RK Q+ +
Sbjct: 11717 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11747
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340
+ L A E+ + + ENK+G ++ + + +D+P P A
Sbjct: 11748 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11805
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
D + + L W YDGGS SY +E + W+ + + + T + V + +
Sbjct: 11806 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11864
Query: 1399 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
Y+FRV+ N G S+ + E+ V E ++P ++++S
Sbjct: 11865 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11903
Score = 61.6 bits (148), Expect = 7e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)
Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143
T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++
Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149
Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194
+SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA +
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209
Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238
+ E + R + + S ATV+ K P+ PPK + PP
Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269
Query: 1239 QI 1240
I
Sbjct: 270 SI 271
Score = 61.6 bits (148), Expect = 7e-09
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
II D ++T A N G ++ + L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505
Score = 61.6 bits (148), Expect = 7e-09
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 1308 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364
+ ++ EN G + + +D DPP G P +I ++TL W Y GG +
Sbjct: 15026 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 15084
Query: 1365 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421
SY +E D N W + F V L D Y+FRV A N G S PS+ S+
Sbjct: 15085 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 15144
Query: 1422 TTVGEKPEEPKDEVEVSDDD 1441
T + E PK +V+V D
Sbjct: 15145 ITCRDDVEAPKIKVDVKFKD 15164
Score = 61.6 bits (148), Expect = 7e-09
Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
PAFK V G+ L + P + W + LK T + + ++I
Sbjct: 15843 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15902
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+ A ED G Y N AG+A + V V D P PP +
Sbjct: 15903 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15944
Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
D T PP K G S+ + V T TW
Sbjct: 15945 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15986
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331
S ++ TI A R + GC + + EN+ G S TV P
Sbjct: 15987 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 16033
Query: 1332 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387
P GTP + S+ + W DGGS V Y +E + + W +L T
Sbjct: 16034 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 16093
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
F L EY+FRV A N+ G +PS+ SE V P +P E +
Sbjct: 16094 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 16152
Query: 1448 DYRTVTINTEQKVSDFYDIEERLGSGKF 1475
++ T + K++ + ++ L G++
Sbjct: 16153 QWKKPTYDGGSKITGYIVEKKELPEGRW 16180
Score = 61.6 bits (148), Expect = 7e-09
Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P +K + VH E K+ + P TI W + L T + + S+S+
Sbjct: 16242 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16298
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+ A+ D G Y AKN AG+ + V V D P PE P V+
Sbjct: 16299 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16341
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275
S T +K PP II + +++ E+ L V Q ++C
Sbjct: 16342 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16391
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330
KV G++ T + ++ NK G + + VV K
Sbjct: 16392 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16431
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388
PD P P + + S+ + W + DGGS + Y +E D W
Sbjct: 16432 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16490
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
V L+ +H+Y+FRV A N G SEPS S
Sbjct: 16491 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16521
Score = 61.6 bits (148), Expect = 7e-09
Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
W+K K + K + G + + + G +G V
Sbjct: 18246 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18296
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388
P P G P A I +++TL W +YDGGS + Y +E D + W + T
Sbjct: 18297 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18356
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
F V L+ D Y+FRV A N G SEPS S T ++ + P ++
Sbjct: 18357 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18405
Score = 61.6 bits (148), Expect = 7e-09
Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W +
Sbjct: 21840 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21895
Query: 1381 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435
+ + R T F V L +EY+F V A N G S S L E P P V
Sbjct: 21896 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21955
Query: 1436 EVSDDDEKEPEVDY 1449
+V+D + +++
Sbjct: 21956 KVTDTSKTTVSLEW 21969
Score = 61.2 bits (147), Expect = 9e-09
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC
Sbjct: 18697 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18753
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
+ F V L + EY FR+ AIN G EP+ E+ E P+ E++
Sbjct: 18754 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18805
Score = 61.2 bits (147), Expect = 9e-09
Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+HV G+ + L ++ PP W G L+ ++ + + + ++I + D G
Sbjct: 23443 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23502
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223
Y KN G + +V + D P P+ E DAT +
Sbjct: 23503 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23547
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
+P P+ A + +++ + + G + ++ +T + KF + + +E+
Sbjct: 23548 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23597
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
+ + A + G Y +++++ ++ + + P PP T D+
Sbjct: 23598 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23638
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396
+TL+WY DGGS V Y +E W NK + RST L
Sbjct: 23639 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23693
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432
EY+ RV AIN G+ +PS+ S+ + KP+ P+
Sbjct: 23694 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23735
Score = 60.5 bits (145), Expect = 2e-08
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T
Sbjct: 13284 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13342
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
F V L+ D +Y+FRV A+N G S+PS
Sbjct: 13343 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13371
Score = 60.5 bits (145), Expect = 2e-08
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 1325 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
+ ++P PP D SS L+W +DGGS + Y +E+ + W E
Sbjct: 22235 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22293
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
+ +F V+ L+ EY+FRV+A N G SEP + + E EP
Sbjct: 22294 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22340
Score = 60.5 bits (145), Expect = 2e-08
Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P + + K + + C++ G P P++ W+ G + Q ++ D +H L
Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 24286
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
++ D G Y+C A+N G++ S L ++ A + P + K + G L
Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 24343
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589
G PVP +TW + +Q + + T E H+ ++ + H G Y N
Sbjct: 24344 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24403
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G V V + +K P KPT PI ++ L + + +S
Sbjct: 24404 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 24440
Query: 650 PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702
PP + W+ N E +E ++ + C E+ G Y A N+ G
Sbjct: 24441 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 24500
Query: 703 ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
+ +V+ ++ P + +P KP ++TA SC +A P
Sbjct: 24501 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 24542
Score = 60.5 bits (145), Expect = 2e-08
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G
Sbjct: 26542 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26600
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
F L IH D G YTC N +G+ + +LT++
Sbjct: 26601 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26637
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384
V KP PP G P D SS++++W YDGGS + Y +EI W+ + A
Sbjct: 15448 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15506
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
++TS+ + L + EYK R+ A+N G EP+
Sbjct: 15507 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15538
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
W K K + MKV + G Y + EN G + + V
Sbjct: 19328 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19376
Query: 1331 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386
DP P G P ++I S++L W YDGG+ + Y +E + + W + +
Sbjct: 19377 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19436
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D
Sbjct: 19437 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19492
Score = 59.7 bits (143), Expect = 3e-08
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
EK P F K + + ++ G A + G P P++ WF + + S ++ +D D
Sbjct: 3643 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3702
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
+ SLII +D+ +YTC A N G+ C+A L + + EG + E E
Sbjct: 3703 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3751
Score = 58.9 bits (141), Expect = 4e-08
Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME-EGEGEGEEEEE 1863
D L I++ +D+ YT A N++G+ + TA L +E + + G++ E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRE 3403
Score = 58.9 bits (141), Expect = 4e-08
Identities = 75/315 (23%), Positives = 117/315 (37%), Gaps = 29/315 (9%)
Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
++ + DS + +P ++ E++ + EVS +L+ TPV + S V
Sbjct: 4332 LQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVS 4391
Query: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524
++ L + + +S + S T A ++ + E + E P + L D
Sbjct: 4392 DEKQDESLKPSEEK-EESSSESGTEEVATVKIQ-----EAEGGLIKEDGPMIHTPLVDTV 4445
Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDH-GT 580
EG L S+ T + W + + + + + L I EDH G
Sbjct: 4446 SEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4503
Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
Y C A N G+ + SA +TV K AP+ + + L+V G
Sbjct: 4504 YVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIEPLEVALGHLA 4546
Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
T ++ P W G EI ES+ SL I D G YTC+A N
Sbjct: 4547 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4606
Query: 701 AGEVRTQAVLTVQEP 715
G V A LTV P
Sbjct: 4607 YGSVSCTATLTVTVP 4621
Score = 58.9 bits (141), Expect = 4e-08
Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)
Query: 1131 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189
W T+K TK + EGSL +++ A+N GQ++ + ++D
Sbjct: 7825 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7868
Query: 1190 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249
+ +++T + PP D T + PPK I ++ ++K
Sbjct: 7869 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7919
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
R G W+K K + +V + G+++ + G
Sbjct: 7920 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7960
Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
+G + ++ P P P +D + ++W +GGS + Y
Sbjct: 7961 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 8014
Query: 1367 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
+E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE
Sbjct: 8015 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 8074
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456
+ +P ++E D E E V +R V + T
Sbjct: 8075 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 8112
Score = 58.9 bits (141), Expect = 4e-08
Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G+ L+ V P TI W K ++ + + + ++ A+ D G Y
Sbjct: 17332 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17391
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
A N AG V V D P P V G S+ K
Sbjct: 17392 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17434
Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
+PP I + +++ E+ L V ++ +T
Sbjct: 17435 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17470
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343
N K+T L E+ + ++ NK G + + V+ K P PP ++I
Sbjct: 17471 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17525
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401
S+T+ W DGGS + Y +E D + W + R T V L DHEY+
Sbjct: 17526 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17585
Query: 1402 FRVRAINVYGTSEPS 1416
FRV A N G EPS
Sbjct: 17586 FRVSAENAAGVGEPS 17600
Score = 58.5 bits (140), Expect = 6e-08
Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V E + +F C ++ + V W +G + + ++ D H L + ++ D G
Sbjct: 5192 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 5248
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+ + +G+ + + RL V + F S L+D V EG+ C + +
Sbjct: 5249 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 5298
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
+ W N + +R+ + + H + + E L +S V E
Sbjct: 5299 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 5346
Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
S+ + + L P F L D ++ ++T+ +VS + P V W +G EI
Sbjct: 5347 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 5397
Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
S + + G + L I++ +D G Y C+ G +T+A +TV+ + +
Sbjct: 5398 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 5448
Query: 725 SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781
KP V +G++ ++ P VH W G+ L + E++++ L+L
Sbjct: 5449 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 5504
Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827
Q G+ N + +V + S + + REP +
Sbjct: 5505 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 5564
Query: 828 CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884
L G + G DR+ ++ G + ++ ED + + +HT
Sbjct: 5565 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 5617
Query: 885 --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938
E IR + + L +D+ K+ V T LS D+++ + + N QR ++V
Sbjct: 5618 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 5669
Query: 939 S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997
S ++E K HS + F+ L+ TS+ V + + KL G
Sbjct: 5670 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 5712
Query: 998 S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055
+ + + VE + + + S PV K + +KP NA
Sbjct: 5713 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 5759
Query: 1056 DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112
+K+ K+ LKK +K+D+ GT + + + + L V V E
Sbjct: 5760 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 5816
Query: 1113 KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ + ++S D W L G+ L T + +EG + S+ + + G
Sbjct: 5817 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 5869
Score = 58.5 bits (140), Expect = 6e-08
Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)
Query: 1090 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147
R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + +
Sbjct: 18394 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18453
Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207
++ ++ + D G Y N G V V D P P
Sbjct: 18454 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18500
Query: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267
V G ++ P A + II+ E ++
Sbjct: 18501 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18542
Query: 1268 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+W + ++Q + K+T L E+ + ++ NK G + + V
Sbjct: 18543 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18588
Query: 1328 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381
KP P TP S I S+ ++W DGG+ ++ Y +E D W +
Sbjct: 18589 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18648
Query: 1382 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
T V L H Y+FRV A N G EPS+ S
Sbjct: 18649 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18686
Score = 58.5 bits (140), Expect = 6e-08
Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T +
Sbjct: 24226 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24284
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + +ED G YTC ATN G + + +L ++ + G P+ K G
Sbjct: 24285 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24335
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
G R GRP P +TW G LQ S +++
Sbjct: 24336 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24373
Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
L + V + G Y + N G ++ IQ D V E N
Sbjct: 24374 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24433
Query: 269 SDV 271
S V
Sbjct: 24434 SAV 24436
Score = 58.5 bits (140), Expect = 6e-08
Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386
+KP P G P + + S ++W + DGG+ +++Y +E + W + T R
Sbjct: 24518 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24576
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE
Sbjct: 24577 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24627
Score = 58.5 bits (140), Expect = 6e-08
Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156
P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++
Sbjct: 25490 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25549
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214
I LPED G Y+ A N AG C + V+ + K+ E R + + L
Sbjct: 25550 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25609
Query: 1215 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250
GTES +A V KPA T K +I + E++K+R
Sbjct: 25610 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25664
Score = 57.8 bits (138), Expect = 1e-07
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1816
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+IS DD +YT N GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 1e-07
Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
+ ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V
Sbjct: 17882 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17941
Query: 1366 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
Y +E+ + W +A + + V L EY+FRV+A N G S+P
Sbjct: 17942 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17991
Score = 57.8 bits (138), Expect = 1e-07
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 1739 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25468 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25527
Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25528 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25587
Query: 1856 GEGEEEEE 1863
E + +EE
Sbjct: 25588 QEFKSKEE 25595
Score = 57.4 bits (137), Expect = 1e-07
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1816
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 57.4 bits (137), Expect = 1e-07
Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
V KP PP D +S+TL+W YDGGS + Y +EI + + W+ +
Sbjct: 17612 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17670
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1442
R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E
Sbjct: 17671 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 17724
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Query: 1302 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358
QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D
Sbjct: 18958 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 19017
Query: 1359 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q
Sbjct: 19018 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19076
Score = 56.6 bits (135), Expect = 2e-07
Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%)
Query: 921 EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 978
E+MD + Q+ V+P T E E K + S ++V + +V ++ K TPV + V +
Sbjct: 4334 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4392
Query: 979 P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 1033
S+ ++K + + S + E K E+ L + GP+ P+ + E
Sbjct: 4393 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4450
Query: 1034 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1083
+ NAK DE K + V + VN + H G
Sbjct: 4451 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4509
Query: 1084 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1138
T + K + + AP K+K++ + VA G C++ S P W G+ +
Sbjct: 4510 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4569
Query: 1139 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1198
+ + + S+ I + D G Y C A N+ G C+ +TV P E
Sbjct: 4570 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4628
Query: 1199 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
+ R+P+ VL + ++K+P PK PK + PE + E V
Sbjct: 4629 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4684
Query: 1256 EL 1257
E+
Sbjct: 4685 EV 4686
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y
Sbjct: 10231 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10288
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
+AKN+AG+ + + V V D P T P + S
Sbjct: 10289 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10328
Query: 1229 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
++ F PED G PIT ++ +++ V
Sbjct: 10329 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10362
Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341
+ T+ Q + + EN +G + +A V + P+ P
Sbjct: 10363 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10421
Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399
++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L
Sbjct: 10422 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10481
Query: 1400 YKFRVRAINVYGTSEPS 1416
Y++RV A+N+ G +PS
Sbjct: 10482 YEYRVSAVNIVGQGKPS 10498
Score = 56.6 bits (135), Expect = 2e-07
Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + ++ V P T+ W + LK T+ + + ++I + + D G Y
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14834
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A+N G+ + V D P PP + D
Sbjct: 14835 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14865
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
+ + F D G V Q + TW++ + + +
Sbjct: 14866 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14914
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
++LT Q + + +N+ G + +V P PP GTP + +
Sbjct: 14915 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14968
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV
Sbjct: 14969 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 15028
Query: 1405 RAINVYGTSEPSQESE 1420
A N+ G S+PS+ SE
Sbjct: 15029 IAENMAGKSKPSKPSE 15044
Score = 56.6 bits (135), Expect = 2e-07
Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)
Query: 1057 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115
E L ++ E + KND A ++ K + + TA Q + G
Sbjct: 22301 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22360
Query: 1116 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
+ +S P + W L LK T + ++ +++++ ++ D G Y +N
Sbjct: 22361 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22420
Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
AG S V V P P + V +++ V PK
Sbjct: 22421 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22467
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
+ I++ E T W ++ ++ K+
Sbjct: 22468 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22497
Query: 1296 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351
T L E+ + + EN+ G S+ + + + P P P + + ++++++
Sbjct: 22498 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22555
Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N
Sbjct: 22556 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22615
Query: 1410 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
G S+ S+ S + + P + EV+D
Sbjct: 22616 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22644
Score = 56.2 bits (134), Expect = 3e-07
Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387
P P P +D S +L+W YDGG + Y +E ++ W + T R T
Sbjct: 14367 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14426
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+
Sbjct: 14427 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14477
Query: 1448 DYRTVTINTEQKVSDFYDIEER 1469
RT+ + + F I+ R
Sbjct: 14478 -RRTLVVRAGLSIRIFVPIKGR 14498
Score = 55.8 bits (133), Expect = 4e-07
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 1726 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1783
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1784 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878
Query: 1844 AELIVETMEE 1853
+L ++ E+
Sbjct: 1879 VKLEIQQRED 1888
Score = 55.8 bits (133), Expect = 4e-07
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 1306 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
GC + ++ EN+ G + V + P PP DI S+++L+W +DG
Sbjct: 14629 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14687
Query: 1360 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
GS + Y IE + W + T + V++L EY F+V A+N G S P +ES
Sbjct: 14688 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14746
Query: 1420 ELTTVGEKPEEPK 1432
V E+ P+
Sbjct: 14747 RPVIVKEQTMLPE 14759
Score = 55.5 bits (132), Expect = 5e-07
Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
AP F Q LQ V V EG + +S P + W +G+ + T+ + +S
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
++I + G Y A N +GQA + ++ V A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
PP +Q + VR G V L +VTG + +
Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
+IQ S ++ + L I A E G Y++ N +G + L V + + P
Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Query: 1335 A 1335
A
Sbjct: 201 A 201
Score = 55.5 bits (132), Expect = 5e-07
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1812
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24619 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24678
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
LII+ V DD Y +A N G + TA L VE
Sbjct: 24679 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24715
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26887
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26888 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26923
Score = 55.1 bits (131), Expect = 6e-07
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388
P PP P +D SS L W DGGS V Y +E + + W++ R T
Sbjct: 10117 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 10174
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D
Sbjct: 10175 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10227
Score = 55.1 bits (131), Expect = 6e-07
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386
KP P P D + L W DGGS + Y +E W + R
Sbjct: 11497 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11556
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
+F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D
Sbjct: 11557 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11611
Score = 55.1 bits (131), Expect = 6e-07
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268
TES + K K P PP++ + +++ E G +TG + +
Sbjct: 12077 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 12134
Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
W+ K MKV+N +H + + EN++G + + V
Sbjct: 12135 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 12183
Query: 1329 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378
DP P G P D S+TL W YDGG+ + Y +E+ S ++ W
Sbjct: 12184 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12243
Query: 1379 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
K A F V L + EY+FRV A N G P++ E E E P+ ++
Sbjct: 12244 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12303
Query: 1436 EVS 1438
+ S
Sbjct: 12304 DAS 12306
Score = 55.1 bits (131), Expect = 6e-07
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399
D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L +
Sbjct: 23340 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23399
Query: 1400 YKFRVRAINVYGTSEPSQESELTTV 1424
Y FR+RA N G SEP + TV
Sbjct: 23400 YLFRIRAQNEKGVSEPRETVTAVTV 23424
Score = 55.1 bits (131), Expect = 6e-07
Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567
AP F L++ V + L C V G P P + W G+ I +Y + G +
Sbjct: 24622 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24681
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I +D Y A N G VS +A + V P+K P L+
Sbjct: 24682 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24727
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP
Sbjct: 24728 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24783
Query: 688 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734
+D G Y A N G + V V +P G + +S+ + AS
Sbjct: 24784 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24843
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA 760
G S + + + WLR G+A
Sbjct: 24844 GGSKITNYIVEKCATTAERWLRVGQA 24869
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383
PDPP I +++ LSW DGGS V Y +E WD + + W++
Sbjct: 9707 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9765
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431
F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P
Sbjct: 9766 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9812
Score = 54.7 bits (130), Expect = 8e-07
Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101
+ G + K + G P P + W+++ + + + L C + T L + + DR
Sbjct: 20580 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 20635
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
G Y + N G+ T+ + + G P+ KT+ E +W
Sbjct: 20636 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 20687
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204
K+ +V++ + R + + +KGN + +P
Sbjct: 20688 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 20747
Query: 205 ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260
SV KN G+ + + + VV A +++S ++ D + +
Sbjct: 20748 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 20807
Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
+ K T D R++VT + + + C+ G P +P
Sbjct: 20808 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 20853
Query: 321 KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378
K D P + + T SSITL ++ + G V GEE +
Sbjct: 20854 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20913
Query: 379 PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421
T + PG+ VS A + P+E P+
Sbjct: 20914 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 20973
Query: 422 -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478
S K + V+ G P P V W + + GS Y E+ S L +
Sbjct: 20974 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 21029
Query: 479 TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528
TR D+G Y T N G+ S T+ V ++L V V+ ++L D +I+G
Sbjct: 21030 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 21088
Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
++ + + TW + + + D + + LAEN
Sbjct: 21089 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 21139
Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637
+G E PV ++ API + D DG
Sbjct: 21140 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 21185
Query: 638 SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697
V V E W H G I ++ + Q Q L + + G
Sbjct: 21186 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 21242
Query: 698 WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
+ G + + ++ E P VT +G +V + G P P++ WL+D
Sbjct: 21243 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 21295
Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817
G L K++ + E+ TL +K + H G+Y ++L N V C V + +
Sbjct: 21296 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 21352
Query: 818 ALPRG 822
+ P+G
Sbjct: 21353 SKPKG 21357
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)
Query: 1308 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
+ + EN G S T+ P P GTP D+ ++TL W DGGS +
Sbjct: 21524 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21583
Query: 1366 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419
YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S
Sbjct: 21584 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21639
Query: 1420 ELTTVGEKPEEP 1431
+ ++ P
Sbjct: 21640 GIIMTRDENVPP 21651
Score = 54.3 bits (129), Expect = 1e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 1746 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 1806 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 1e-06
Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%)
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
G+ + +V K + R+ + G R KF S + Q VKE +T F CE+S K V W
Sbjct: 5247 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 5301
Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
F + ++ + + +H L + + D +L
Sbjct: 5302 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 5351
Query: 508 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565
V+E P F+ L D +E + L+C V VP + W +G+ I S G+
Sbjct: 5352 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 5409
Query: 566 AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
L I+ A +D G Y C G A VTV + + KP
Sbjct: 5410 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 5451
Query: 625 FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684
L ++V G +++S P W G + S D + G +H L +
Sbjct: 5452 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 5506
Query: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744
TG + +A N+ ++ A L V+E FI+ V C +
Sbjct: 5507 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 5558
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782
+ +P T WL+ + + D FE++++ ++V+K
Sbjct: 5559 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 5594
Score = 54.3 bits (129), Expect = 1e-06
Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158
F+ KL + G+ L + S P + W + L+ + I + +L I
Sbjct: 10519 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10574
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
KA D G Y V +N G + CQV V D P PPV
Sbjct: 10575 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10616
Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
D K P I +K G+ V + + + TC K K +
Sbjct: 10617 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10672
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
+ +++ ++EN Y + S +A+ V D PD P T
Sbjct: 10673 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10717
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395
D S ++W +DGG + +Y +E ++ +K W + T F V DLL
Sbjct: 10718 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10772
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448
+Y+FRV A N G +PS S+ + +P V D VD
Sbjct: 10773 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10825
Score = 54.3 bits (129), Expect = 1e-06
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QL PV++K L PP F V G+ + GRP
Sbjct: 15828 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15870
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A
Sbjct: 15871 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15924
Score = 54.3 bits (129), Expect = 1e-06
Identities = 26/77 (33%), Positives = 44/77 (57%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y
Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16995
Query: 232 TCLVVNGSGKASMSAEL 248
V N G+ + S E+
Sbjct: 16996 GITVANVVGQKTASIEI 17012
Score = 54.3 bits (129), Expect = 1e-06
Identities = 25/72 (34%), Positives = 40/72 (55%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G+ + + GRP+P ++W+K PL+ + RV+V E VL I N+DD G Y
Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077
Query: 232 TCLVVNGSGKAS 243
T N +G A+
Sbjct: 18078 TVTATNSAGTAT 18089
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1814
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25443
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25444 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 53.9 bits (128), Expect = 1e-06
Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 1736 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
+S + + A L V P +K + I LEV G A+F C+I+ P+ WFK
Sbjct: 4511 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4566
Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
+ I ES I + + SL I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4567 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4624
Score = 53.9 bits (128), Expect = 1e-06
Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16706
Query: 232 TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260
T + N SG + SA ++++ LD+ +
Sbjct: 16707 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 16764
Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311
V + +AT VTN K+D L+ A P + P A
Sbjct: 16765 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 16824
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363
PQPP + ++ + + T S I +Q + R L
Sbjct: 16825 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16883
Query: 364 LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411
+ + GEE K + PR P + ++D+V +
Sbjct: 16884 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 16924
Query: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
P + S V+ Q +K +SG PKP + W +G P+ +Q I V +
Sbjct: 16925 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 16981
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCS 499
L + + D G Y T +N GQ + S
Sbjct: 16982 LSIKETHKDDGGQYGITVANVVGQKTAS 17009
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26536 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26595
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26596 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26645
Score = 53.1 bits (126), Expect = 2e-06
Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R GRP P++TW + + +V + + L I +++D G
Sbjct: 17729 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17786
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D
Sbjct: 17787 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17838
Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328
AK KN +R + AN + + S K+E+ +
Sbjct: 17839 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17897
Query: 329 ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375
P + P L +TS+S+ + R G V + P G E K
Sbjct: 17898 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 17956
Query: 376 PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423
GL S KA N + +P+ + + P + +
Sbjct: 17957 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 18016
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
++ + +K V G P+P ++W +G P+ +Q + V E A S L + + D G
Sbjct: 18017 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 18075
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
Y+ TA+N+ G + + ++ V V P F V D VI
Sbjct: 18076 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 18119
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G
Sbjct: 21663 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21722
Query: 230 VYTCLVVNGSGKASMSAELSIQ 251
VYT N SG A ++ +Q
Sbjct: 21723 VYTVEAKNASGSAKAEIKVKVQ 21744
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24287
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24288 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24318
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
PT + + V G V + + ++G PPP W G++++ESE E
Sbjct: 23431 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23490
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734
L I+E DTG YT E N G T V+ + +P T P I + S+T S
Sbjct: 23491 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23550
Query: 735 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790
G + L + WL +++ + T F L + + + + G
Sbjct: 23551 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23610
Query: 791 QYEILLKNRVGECSCQVSL 809
Y L++ V EC + +
Sbjct: 23611 SY---LQSEVIECRSSIRI 23626
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
LVI +D G+YT N G + L E +
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131
Score = 52.4 bits (124), Expect = 4e-06
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 1730 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1789
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 15816 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15874
Query: 1790 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 15875 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15932
Score = 52.4 bits (124), Expect = 4e-06
Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280
K P TP PP+ P + SV L K G +T +++ ++ +
Sbjct: 24010 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 24069
Query: 1281 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332
H K + + +T L E+ + ++ +N +G S + + VV DKP
Sbjct: 24070 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 24127
Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390
P S I S+TL W DGG + Y +E S + WK+ + F
Sbjct: 24128 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 24186
Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438
+ LL EY+FRV A N G S P S +++LT+ GE P K+ +V+
Sbjct: 24187 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24238
Score = 52.4 bits (124), Expect = 4e-06
Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P F+ + ++ V+ C+V+G PKP V W+ +G + + E G ++
Sbjct: 24623 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24682
Query: 474 LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
++ + T D T Y A+N G +S + +L+VE A + + P + + G+
Sbjct: 24683 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 24741
Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587
++ G P P ITW GQ + + V P +D G Y A+N
Sbjct: 24742 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 24800
Query: 588 ALG 590
G
Sbjct: 24801 RFG 24803
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G
Sbjct: 25273 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25332
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
Y C VVN G+ S AEL ++G+ + R T
Sbjct: 25333 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25367
Score = 52.0 bits (123), Expect = 5e-06
Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
++ H+ G L L + P + W + T I ++ GS + I A ED
Sbjct: 10921 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10978
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
G+Y +N AG S +V V D P P+ + +S K
Sbjct: 10979 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 11026
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+P G SV V + W ++ H
Sbjct: 11027 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 11064
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341
+E L +AA EN+ G + DP P G P
Sbjct: 11065 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 11112
Query: 1342 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
D+ + ++L W DGGS + Y +E + + W + T + V L
Sbjct: 11113 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 11172
Query: 1400 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
Y+FRV+A N+ G P + EK P E++V
Sbjct: 11173 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11209
Score = 52.0 bits (123), Expect = 5e-06
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R
Sbjct: 21663 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21721
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G YT EA N SG+ + +++ V+ + K +G + G++ +
Sbjct: 21722 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21765
Score = 51.6 bits (122), Expect = 7e-06
Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%)
Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469
++A P F + QS V++ V+ + V+GIP P V ++ +G + + ++ ++
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158
Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
+ L + +A DSGTYS A+N+ G+ + + L V+
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 51.6 bits (122), Expect = 7e-06
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327
W K K + + H KV G + + EN G +
Sbjct: 20411 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20459
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
+D +PP +DI +S++LSW ++DGGS + Y +E D + W +
Sbjct: 20460 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20518
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417
T F + L + +Y+FRV A N G+ S PS+
Sbjct: 20519 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20551
Score = 51.2 bits (121), Expect = 9e-06
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385
+ P PP P +D S+++ L W +++GG + Y ++ W +
Sbjct: 8695 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8752
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
+ V+++ +YK RV A+N G P E++ TV E E P E++VS
Sbjct: 8753 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8804
Score = 50.8 bits (120), Expect = 1e-05
Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)
Query: 1125 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183
PP T+ W + K L + + S ++I + D G Y +N G+ + S
Sbjct: 20994 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 21053
Query: 1184 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238
V V D PA+ + SR + L PP++ S + ++K+ A K
Sbjct: 21054 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 21105
Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298
TW + + ++ SE
Sbjct: 21106 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 21131
Query: 1299 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356
+ +L EN++G + V + PA S D +S+ LSW
Sbjct: 21132 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 21182
Query: 1357 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
+DGGS + Y +E +TW ++ V L +FRV A N G S+P
Sbjct: 21183 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21242
Query: 1417 QESELTTVGEKPEEPKDEVEVSD 1439
+ TV E P EV++SD
Sbjct: 21243 TIGPI-TVKELIITP--EVDLSD 21262
Score = 50.8 bits (120), Expect = 1e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343
SE K+T L E+ + ++ EN G A L +P P G P +D
Sbjct: 21903 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21960
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401
++++L W +DGG + Y IE+ + W ++ C T + V DL EYK
Sbjct: 21961 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 22020
Query: 1402 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
FRV AIN G + + + ++ P+ +++ +
Sbjct: 22021 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 22057
Score = 50.1 bits (118), Expect = 2e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
G P + + VT LG++ +SC I G P P + W R GK L + + +++ +
Sbjct: 24225 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24283
Query: 778 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
TL + + G Y + N VGE L+LQ
Sbjct: 24284 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24318
Score = 49.7 bits (117), Expect = 3e-05
Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)
Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
S P E + E P F L + VK G +TG+P+P++TW K ++ L+
Sbjct: 7368 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7427
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
R+++ + I + D G Y VN G+A+ E+++
Sbjct: 7428 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7487
Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
D N S + D ++TN + + DS
Sbjct: 7488 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7522
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
P PP G P S+ +SW +GGS + Y +E + + W ++
Sbjct: 9294 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9352
Query: 1385 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439
+ FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D
Sbjct: 9353 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9410
Score = 49.7 bits (117), Expect = 3e-05
Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + L V PP I W+ L+ + + + E D G Y
Sbjct: 13403 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13462
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
+N G+ E + V V D P PPV T + + P
Sbjct: 13463 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13504
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
P II + ++ + K T C+ FR V N E
Sbjct: 13505 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13547
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348
G + + EN+ G V P G +RS SS
Sbjct: 13548 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13595
Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408
++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N
Sbjct: 13596 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13654
Query: 1409 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
G P SE+T V +D+V D D K
Sbjct: 13655 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13680
Score = 49.7 bits (117), Expect = 3e-05
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+
Sbjct: 16933 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16991
Query: 789 AGQYEILLKNRVGECSCQVSLM 810
GQY I + N VG+ + + ++
Sbjct: 16992 GGQYGITVANVVGQKTASIEIV 17013
Score = 49.7 bits (117), Expect = 3e-05
Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G
Sbjct: 18812 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18869
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
Y + N SG S +A ++++ LDS + +RE K + D ++TN
Sbjct: 18870 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18927
Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
I ++ + A + NC+ Q G S + + + E+ +
Sbjct: 18928 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18987
Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
+ P P + T +T A ++ E + G V + K + T
Sbjct: 18988 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 19047
Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431
GL G + V AA R P E KP + VK + +
Sbjct: 19048 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 19107
Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
K G P+ V W +G + ++ + V L + +A D GTY SN
Sbjct: 19108 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 19166
Query: 492 AQGQLSCSWTLQV 504
+ G ++ T+ V
Sbjct: 19167 SAGSITVPITIIV 19179
Score = 49.3 bits (116), Expect = 4e-05
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 13059
Query: 230 VYTCLVVNGSGKASMSAELSI 250
YT N SG S + +L +
Sbjct: 13060 DYTITAENSSGSKSATIKLKV 13080
Score = 48.9 bits (115), Expect = 5e-05
Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)
Query: 1131 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D
Sbjct: 14108 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14167
Query: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
P PP S+ + +K TPP I + +++
Sbjct: 14168 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14207
Query: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310
E+ L W + IQ H+ + + G++ + H G
Sbjct: 14208 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14248
Query: 1311 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
G + +VD+ P P P S++ ++ T+SW DGGS + Y +
Sbjct: 14249 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14303
Query: 1369 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426
E + + W + V L Y+FRV A N G PS+ S+ + +
Sbjct: 14304 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14363
Query: 1427 K--PEEPKDEVEVSDDDEK 1443
P P V+D +K
Sbjct: 14364 AAYPPGPPSNPHVTDTTKK 14382
Score = 48.5 bits (114), Expect = 6e-05
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)
Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
I++T++++ P S P+T A +PPR L +K G + V G P P
Sbjct: 12962 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 13020
Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++
Sbjct: 13021 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 13077
Query: 121 LTV 123
L V
Sbjct: 13078 LKV 13080
Score = 48.5 bits (114), Expect = 6e-05
Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)
Query: 1325 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
+ +D PP P +D +S++L+W +GGS V Y IE+ W +
Sbjct: 23719 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23776
Query: 1383 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
C +T +++ H EY+FRV A N G EP++ V E E P E++
Sbjct: 23777 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23834
Score = 48.1 bits (113), Expect = 8e-05
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566
+ + PS ++ G+D ++ V G P P I+W+ +G+P+ Q R E A
Sbjct: 18003 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 18062
Query: 567 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
LHI++ +D G YT A N+ G + + V V EK
Sbjct: 18063 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 18099
Score = 48.1 bits (113), Expect = 8e-05
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QLG PV+++ +E +PS+ E P F T VK + + GRP
Sbjct: 19075 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 19117
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ +
Sbjct: 19118 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 19175
Query: 249 SIQGLD 254
+I LD
Sbjct: 19176 TIIVLD 19181
Score = 48.1 bits (113), Expect = 8e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)
Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
C TN ELT + + + V ++ D S P+ T P I + PP+
Sbjct: 19429 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19484
Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
+ +VVK G++ + + I GRP P ++W K + ++ AR + + +L +
Sbjct: 19485 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19544
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ D G Y + N +G S++ +
Sbjct: 19545 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19574
Score = 48.1 bits (113), Expect = 8e-05
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)
Query: 1700 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1759
AV + + S M S + KS L++ + + ++ A LE + E+
Sbjct: 26190 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26249
Query: 1760 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
T+ R + V EG +ARF C +G P P V W + Q + S Q+ +
Sbjct: 26250 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26308
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ IS V D+ Y+ NS G+ L ++
Sbjct: 26309 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26346
Score = 47.8 bits (112), Expect = 1e-04
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1808
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.8 bits (112), Expect = 1e-04
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 1263 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322
G P+T ++ ++++ KV + + T+ Q + + NK G +
Sbjct: 7210 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268
Query: 1323 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376
VN+ T PDPP D ++S+ L+W DGGS ++ Y +E +
Sbjct: 7269 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7327
Query: 1377 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
W T V L Y +RV+A+N G S+PS+ +E + E P+ +
Sbjct: 7328 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7387
Query: 1436 EV 1437
+V
Sbjct: 7388 DV 7389
Score = 47.8 bits (112), Expect = 1e-04
Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%)
Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478
K ++ + G P P+ +W +G + ++G ++ EDA S + + + +
Sbjct: 9518 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9577
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531
+G YS TA N GQ + + ++V + L V ++ + +G D
Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 9636
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
++G + + T ++G+ C G + D L E + AEN G
Sbjct: 9637 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 9687
Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
V ++ ++R P+ P P +K+ G TV +S PP
Sbjct: 9688 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 9730
Query: 652 PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
+ W G + + + ++ + ++++ + +A
Sbjct: 9731 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 9789
Query: 699 NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756
N+AG + A + + P I + G +V I I G PFPT+ W +
Sbjct: 9790 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 9849
Query: 757 ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
D K H L +D TLV+ + + G Y I N +G S ++ L
Sbjct: 9850 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9906
Score = 47.8 bits (112), Expect = 1e-04
Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)
Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630
P D + +A NA+G +S S+ S ++ V P P + GL
Sbjct: 21615 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21664
Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
+ G + + V G P P V W +G EI++ + SL +++ +
Sbjct: 21665 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21721
Query: 691 GTYTCEAWNSAGEVRTQAVLTVQE 714
G YT EA N++G + + + VQ+
Sbjct: 21722 GVYTVEAKNASGSAKAEIKVKVQD 21745
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
+++P PP +SD SS+ L W DGGS + Y IE + W +
Sbjct: 6984 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 7042
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
++ V L ++Y +RV A N G S+PS+ T + EP ++ D
Sbjct: 7043 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 7097
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)
Query: 574 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632
+P++ T T L E A Q A V+ S S+ + +A + P + + S L
Sbjct: 12941 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 13000
Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689
V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D
Sbjct: 13001 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 13057
Query: 690 TGTYTCEAWNSAG 702
+G YT A NS+G
Sbjct: 13058 SGDYTITAENSSG 13070
Score = 47.4 bits (111), Expect = 1e-04
Identities = 25/82 (30%), Positives = 36/82 (43%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
+ KE R I G+P P V+W KG PL RVSV L ++ + D G
Sbjct: 13688 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13747
Query: 231 YTCLVVNGSGKASMSAELSIQG 252
YT + N +G + + + G
Sbjct: 13748 YTITLKNVAGTKEGTISIKVVG 13769
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T
Sbjct: 18003 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 18062
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
L I +++D GKYT ATN +G + + V
Sbjct: 18063 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 1731 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 21627 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21686
Query: 1791 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21687 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744
Score = 47.4 bits (111), Expect = 1e-04
Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
I+ G+ + V G PEP++ W + + + + L G R T VI D G
Sbjct: 22754 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22811
Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
KYT N SG + V+V + V S G+ VS+ ++ +S P + I
Sbjct: 22812 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22870
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
+ T V+ EG+ S +T + +V + P P + +N
Sbjct: 22871 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22930
Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
+ G+ ++ G ++ ++ E+S +D + +R T+
Sbjct: 22931 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22990
Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
D R +VT+++ + C R + A NS+P S SC++
Sbjct: 22991 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 23033
Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
P +AP+ V+ T SI+L + + +G + E+ A
Sbjct: 23034 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 23091
Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420
R F +G + AA + ++G + + E +P
Sbjct: 23092 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 23148
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479
++ ++ +++ VSG P P + W +G + S + + S+ L ++ K
Sbjct: 23149 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 23204
Query: 480 RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
D+G Y+ A N G+ S + ++V + V EV+ ++ + I+G
Sbjct: 23205 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 23260
Query: 533 LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590
G PV I + T + I + + L EN G
Sbjct: 23261 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23314
Query: 591 --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
S V V E +P+ P+K L+V+D ++ T+T ++
Sbjct: 23315 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 23350
Query: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705
P L++G + GT+ + + + P E T T E +R
Sbjct: 23351 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23405
Query: 706 TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752
Q V EP + + R ++ G+ V + IAG P P
Sbjct: 23406 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 23465
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
W G L +++ V + V L +++ G+Y + LKN G S + +++
Sbjct: 23466 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 23524
Query: 813 NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
+ A ++ EP + GG G ++ + RPGW
Sbjct: 23525 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 23574
Score = 47.4 bits (111), Expect = 1e-04
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387
P PP G P + + W DGG+ + +Y ++ + + W + T
Sbjct: 22935 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22993
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
V L+ +Y+FRV A+N G SEPS+ S + E P
Sbjct: 22994 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 23037
Score = 47.4 bits (111), Expect = 1e-04
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
V + S S++ ++P +P E + + + I+ GA+ + V G P P
Sbjct: 23115 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 23172
Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V
Sbjct: 23173 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23229
Score = 47.0 bits (110), Expect = 2e-04
Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%)
Query: 988 KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 1045
++++ + +GS E + VES +S + S V K + +A ++
Sbjct: 4333 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4392
Query: 1046 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1105
K + KP E + +S E ++V V + G + P L
Sbjct: 4393 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4442
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1164
D EG + L +++ + W K + + + Q+ + ++ I+K ED
Sbjct: 4443 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4500
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
+G Y C A ND+G+ S ++TV K
Sbjct: 4501 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4525
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+ AP K E +V G + ++ + W K ++I ES+
Sbjct: 4526 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4575
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+ +S+ S L IL + CG YT N+ GS LTV
Sbjct: 4576 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618
Score = 47.0 bits (110), Expect = 2e-04
Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%)
Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 810
V+W + K + D F+ LQ+++ +TLV+ KV H G+Y N G+ + L
Sbjct: 4464 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4522
Query: 811 LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 870
+ +A + R EP ++ G + ++R W G+ + E D +R
Sbjct: 4523 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4578
Query: 871 G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 917
+L+ +V + ++T +A + L G+K K L E K
Sbjct: 4579 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4636
Query: 918 IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 963
P E++ ++ L++ + +PK ++ KV P ++V+ +V ++
Sbjct: 4637 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4694
Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 1023
K P P KVP KPA P LPA E A+ P +P+
Sbjct: 4695 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4740
Query: 1024 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1083
PV P K A E KP G P + + + ++ + + G
Sbjct: 4741 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4795
Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1137
+ + + F ++++D+ + E G + +C VS P+T I W +G
Sbjct: 4796 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4852
Query: 1138 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
++ + +FI ++ L + ++ + D G Y CV + + + ++ V++ P
Sbjct: 4853 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4906
Score = 47.0 bits (110), Expect = 2e-04
Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)
Query: 1111 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169
EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+
Sbjct: 25276 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25335
Query: 1170 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228
C ND G+ ++ V + + RR T+KK K
Sbjct: 25336 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25375
Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285
T PP+ ++ GE+V +T TW K ++I+ ++ K
Sbjct: 25376 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25435
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334
E+ + +LTI + + YT++ NK G + LTV P P
Sbjct: 25436 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25495
Query: 1335 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
G +IR S + TL W DG +IEI +
Sbjct: 25496 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25546
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
+ +++D LP+ +RV A N G++ ++ + K +E K + E +K+
Sbjct: 25547 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25603
Query: 1445 PEVDYRTVTI 1454
+ R I
Sbjct: 25604 IDKTLRMAEI 25613
Score = 46.2 bits (108), Expect = 3e-04
Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+ + + +G A FE V G P P VTW + + + + + + G+ + +
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144
++ ED G Y C+A N G EL V P +K+ +
Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3886
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PAVE S + AT + ++K + + +++ + L +PL
Sbjct: 3887 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3941
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260
S+ E++ + + + C +NGS S L +Q + S ++F
Sbjct: 3942 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3990
Query: 261 VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ ET+A SD K + +S E +++SL + P+ G P
Sbjct: 3991 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 4044
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353
S +PP S L S + +P+ + T+ +TLQ Q
Sbjct: 4045 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 4087
Score = 46.2 bits (108), Expect = 3e-04
Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444
GLG D IP+E Q P E + E VK TV+F + G+P P
Sbjct: 11184 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 11236
Query: 445 VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504
W +G+ ++ E V D S L + RD+G Y T SNA G + + L V
Sbjct: 11237 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
LP KE + + + ++G P P V+W + P+ + R ++ T +L+++
Sbjct: 13682 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13740
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125
+ D GKYT N +G ++ T+ + V G
Sbjct: 13741 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13769
Score = 46.2 bits (108), Expect = 3e-04
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 1717 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1771
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 26376 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26435
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 26436 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26486
Query: 1832 K 1832
+
Sbjct: 26487 E 26487
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I +
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188
D G YK + G+ E +C ++V+
Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 6067 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6122
Query: 1814 CSLIISDVCGDDDAKYTCK 1832
L+I+ DD+A+Y+C+
Sbjct: 6123 RILVINKCLLDDEAEYSCE 6141
Score = 45.8 bits (107), Expect = 4e-04
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565
++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G
Sbjct: 21652 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21708
Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
L ++DA + G YT A+NA G V V +
Sbjct: 21709 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21745
Score = 45.4 bits (106), Expect = 5e-04
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 45.4 bits (106), Expect = 5e-04
Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%)
Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
RQ TV+ EG+ K V + G P ET+P E A +L G
Sbjct: 8754 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8808
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ + G+ R +TGRP P W K L RV + L I + D G
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8867
Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
Y N G +A L ++ + + + + D E+T I
Sbjct: 8868 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8927
Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
K++K+ + +E + + G + ++ + PP E D
Sbjct: 8928 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8987
Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
P T+P+ ++T S+ITL EPR+ G + E++R P
Sbjct: 8988 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 9043
Query: 382 FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423
PT + + D KA N +P+ Q D P + + +
Sbjct: 9044 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 9103
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478
+VK + V +V+G+P P++ W T + + ++++ ++ S L + KA
Sbjct: 9104 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9163
Query: 479 TRDSGTYSCTASNAQGQL 496
D GTY+ TASN G +
Sbjct: 9164 REDKGTYTVTASNRLGSV 9181
Score = 45.4 bits (106), Expect = 5e-04
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%)
Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567
+V P+FSS +V GQD ++ + G P P ITW +G P++ T +
Sbjct: 16926 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16981
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I++ +D G Y N +GQ + S + +K P P P+
Sbjct: 16982 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 17028
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPP 651
+S ++ +S NPP
Sbjct: 17029 DVS----------AESITLSWNPP 17042
Score = 45.4 bits (106), Expect = 5e-04
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
+ G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y
Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077
Query: 694 TCEAWNSAG-EVRTQAVLTVQEP 715
T A NSAG +V+ +++P
Sbjct: 18078 TVTATNSAGTATENLSVIVLEKP 18100
Score = 45.1 bits (105), Expect = 7e-04
Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+K G + E V G P P + W ++G+ + + + T +LV D G
Sbjct: 15168 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15226
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160
YT ATN G FAK + V G + V + + P
Sbjct: 15227 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15273
Query: 161 P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215
P K+ +V++ + R + + QVT LK L+ + RV K G+
Sbjct: 15274 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15332
Query: 216 -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256
VL ++ D + C S S ++ D A
Sbjct: 15333 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 15392
Query: 257 NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315
+ +++ K T +D+R +V+ + E + + A + SP +P
Sbjct: 15393 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 15452
Query: 316 PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366
PP + L++ + S A P+ S PE P A GL S
Sbjct: 15453 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 15511
Query: 367 SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423
+ + + GLG +V KA +R +P E + D+ K +
Sbjct: 15512 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 15566
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481
++ T++ + G P PEV W + E + ++ S Y L+ D
Sbjct: 15567 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 15620
Query: 482 SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
SG Y T N+ G S ++V + L V EV + ++ D +++G +
Sbjct: 15621 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15680
Query: 535 CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593
V R + + C ++ D L E Y LAEN G +
Sbjct: 15681 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 15729
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
A K S R P+ P K T +MD ++ +V +S P
Sbjct: 15730 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 15768
Query: 654 VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
H+G + +G+ + + C E T T + + V Q +
Sbjct: 15769 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 15824
Query: 713 QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
+P + P I+K + T G+ + + G P P V W +D L
Sbjct: 15825 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15883
Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
K T E+ L +K G Y + L N GE
Sbjct: 15884 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 15923
Score = 45.1 bits (105), Expect = 7e-04
Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)
Query: 1228 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284
P PP A P++ + +R E G I W+ K R I +
Sbjct: 22532 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22586
Query: 1285 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
KV E K+T L E+ Y L + +A + + D P G P +D+
Sbjct: 22587 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22645
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398
S+++L W +YDGGS V Y IE + + + W + F V L
Sbjct: 22646 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22705
Query: 1399 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
Y+FRV A N G S+ S+ + T ++ PK E++
Sbjct: 22706 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22744
Score = 44.7 bits (104), Expect = 9e-04
Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%)
Query: 656 WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
W+ +G+ I+ES F G L I +V D G YTC E + A L V+E
Sbjct: 4846 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905
Query: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
+ + VT GQ + +SC + + V W +DGK + + G
Sbjct: 4906 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 4960
Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810
+ L + AG Y + ++N ECS V ++
Sbjct: 4961 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 4996
Score = 44.7 bits (104), Expect = 9e-04
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386
P P G P D+ S+++L W +DGGS + Y +E W T
Sbjct: 12884 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12943
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
+ L +Y+FR A S PS+ S+ T+ + P+ ++ V+
Sbjct: 12944 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12995
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
L +K G T +F +RG P P W +G I + + ++ FS L I
Sbjct: 11215 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11271
Query: 100 DRGKYTCEATNGSGARQVTVELTV 123
D G+Y +N +G++ V V LTV
Sbjct: 11272 DTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)
Query: 601 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
+EK S + +PV A P F + V+ G + + V G P P V W +
Sbjct: 15820 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15879
Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718
++++ + E L I++ ED G Y + NSAGE + T V+ + +P
Sbjct: 15880 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15939
Query: 719 TQP 721
T P
Sbjct: 15940 TGP 15942
Score = 43.9 bits (102), Expect = 0.001
Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+V+ G R + GRP P+VTW K + + V + M L I +DD G
Sbjct: 12311 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12369
Query: 230 VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279
Y+ +VN +G+ ++ + + + S V +T +D +VT+ I
Sbjct: 12370 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 12429
Query: 280 SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311
++ + D A P P A++
Sbjct: 12430 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 12489
Query: 312 --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365
S+P PPR+ ++ + T P L+ K IT QP R V+
Sbjct: 12490 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 12549
Query: 366 ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413
G++ K R A + P G V +A + +P
Sbjct: 12550 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 12594
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
PK P+ +K + ++ V G P P W +G + V++ S L
Sbjct: 12595 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 12652
Query: 474 LLKARTRDSGTYSCTASNAQG 494
+ +DSG YS TA N+ G
Sbjct: 12653 IKDVTRKDSGYYSLTAENSSG 12673
Score = 43.9 bits (102), Expect = 0.001
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L
Sbjct: 12594 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12652
Query: 220 IHGVNQDDVGVYTCLVVNGSG 240
I V + D G Y+ N SG
Sbjct: 12653 IKDVTRKDSGYYSLTAENSSG 12673
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)
Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
VK V ++ +SK S +V P R D P + F+ ++EG +++G P
Sbjct: 9786 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9839
Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
P +TW + N +P+ T + ++D T +LVI D G YT A N
Sbjct: 9840 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9895
Query: 111 GSGARQVTVELTVEG 125
G + L V G
Sbjct: 9896 NLGTASKEMRLNVLG 9910
Score = 43.1 bits (100), Expect = 0.003
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 0.003
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1819
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9821 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9879
Query: 1820 DVCGDDDAKYTCKAVNSLGEAT 1841
D YT AVN+LG A+
Sbjct: 9880 QSRRSDTGLYTITAVNNLGTAS 9901
Score = 43.1 bits (100), Expect = 0.003
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
Y N SG A SA +++ LD + K TN V KE IS E+ LD+
Sbjct: 11673 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11723
Score = 43.1 bits (100), Expect = 0.003
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12583 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12642
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12643 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12683
Score = 43.1 bits (100), Expect = 0.003
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 1731 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1787
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 16212 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16268
Query: 1788 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 16269 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16327
Query: 1848 V 1848
V
Sbjct: 16328 V 16328
Score = 43.1 bits (100), Expect = 0.003
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390
P PP S + S+TL W DGGS + Y IE + + W +
Sbjct: 19678 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19736
Query: 1391 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421
V+ L EY++RV A N G S PS+ S L
Sbjct: 19737 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19769
Score = 42.7 bits (99), Expect = 0.003
Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)
Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150
+G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
+++++ ED+G Y V
Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293
Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
+ G ++ +K KP P I+Q DQKV G+ V+L KV+ + +
Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401
Query: 1331 PDP 1333
P
Sbjct: 2402 ITP 2404
Score = 42.7 bits (99), Expect = 0.003
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 1760 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1813
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4812 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4869
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
+I DV D +YTC E T TA+L+VE +
Sbjct: 4870 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)
Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
+ + TV G Q + V++K S P+ T P + PKF
Sbjct: 17271 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17329
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
+VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D
Sbjct: 17330 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17387
Query: 228 VGVYTCLVVNGSGKASMSAELSI 250
G Y N +G S + +
Sbjct: 17388 GGQYILRASNVAGSKSFPVNVKV 17410
Score = 42.4 bits (98), Expect = 0.004
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107
+KS K +++ K + + +N + H G + + T+ A F++ ++D+
Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021
Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167
V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G
Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080
Query: 1168 YKCVAKNDAGQAE 1180
Y VA + A+
Sbjct: 3081 YTVVAGGNVSTAK 3093
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
+K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y
Sbjct: 10925 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10982
Query: 232 TCLVVNGSGKASMSAELSI 250
+ V N +G ++S ++ +
Sbjct: 10983 SLTVENPAGSKTVSVKVLV 11001
Score = 42.4 bits (98), Expect = 0.004
Identities = 21/72 (29%), Positives = 34/72 (47%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++++ G R + GRP P++TW K NV L+ + + + L VN+ D G
Sbjct: 13398 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13457
Query: 230 VYTCLVVNGSGK 241
Y + N GK
Sbjct: 13458 KYILTLENSCGK 13469
Score = 42.4 bits (98), Expect = 0.004
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + + V G P P V W +++++ +FE T L I E D+G Y
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14834
Query: 697 AWNSAGEVRTQAVLTVQ 713
A N GEV V+T+Q
Sbjct: 14835 ARNIVGEVGD--VITIQ 14849
Score = 42.4 bits (98), Expect = 0.004
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576
KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+
Sbjct: 16245 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16304
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633
D G Y A+N G+ S VTV+ K R P P P+ + G++ K
Sbjct: 16305 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16351
Query: 634 -----VMDGSQVTMTVQVSGNPPPEVIW 656
+ DG + V ++W
Sbjct: 16352 AWKPPLQDGGSDIINYIVERRETSRLVW 16379
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16924 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16978
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
+L I + DD +Y N +G+ T + E++
Sbjct: 16979 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 17013
Score = 42.4 bits (98), Expect = 0.004
Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 736 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795
+ + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+
Sbjct: 19105 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19163
Query: 796 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
+ N G + +++++ + P + SC+ +
Sbjct: 19164 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19199
Score = 42.0 bits (97), Expect = 0.006
Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158
F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I
Sbjct: 5982 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 6039
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
PED Y C DA + SC + V
Sbjct: 6040 DCTPEDIKTYTC----DAKDFKTSCNLNV 6064
Score = 42.0 bits (97), Expect = 0.006
Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E F N+ + E T K V P +V W++ + I GR+ + R
Sbjct: 6154 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6212
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
LVI H ED G Y C + +V V
Sbjct: 6213 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6243
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
E +F +K + + EG+ F C I+ P V W + + L+ +
Sbjct: 6244 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6293
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V +VL + D+G Y +V G A +A L++
Sbjct: 6294 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6331
Score = 42.0 bits (97), Expect = 0.006
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578
G+ + V G P+P+I W N I+ + EL I A+ ED
Sbjct: 9108 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 9167
Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKS 605
GTYT A N LG V + V V+++ S
Sbjct: 9168 GTYTVTASNRLGSVFRNVHVEVYDRPS 9194
Score = 42.0 bits (97), Expect = 0.006
Identities = 26/93 (27%), Positives = 39/93 (41%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
P+ + ++ + L V G+ V + G P P W +G+EI+ E + E
Sbjct: 11203 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11262
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
L I+ DTG Y N+AG LTV
Sbjct: 11263 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 42.0 bits (97), Expect = 0.006
Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%)
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
V G P P+V W G ++G +++ + +L + + DSG YS T N G+
Sbjct: 12325 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 12382
Query: 497 SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
+ ++V L V +V + V +G V V R TW
Sbjct: 12383 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 12440
Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
+ T E H+ + +P + + A N G V K S
Sbjct: 12441 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 12488
Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666
+ L S+P P + ++ +++T PP L +G +
Sbjct: 12489 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 12530
Query: 667 ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716
E+ R T++S+ ++++ TG + A N+ G + V E
Sbjct: 12531 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 12589
Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
+ P I P +T G+ + I + G P PT W + G+ + H V + +
Sbjct: 12590 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 12648
Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
L++K V +G Y + +N G + ++ +++ ++ P
Sbjct: 12649 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 12692
Score = 42.0 bits (97), Expect = 0.006
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+T G +V + + G P PTV W +DG L K ++ ++ TL L V +
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 13058
Query: 790 GQYEILLKNRVGECSCQVSL 809
G Y I +N G S + L
Sbjct: 13059 GDYTITAENSSGSKSATIKL 13078
Score = 42.0 bits (97), Expect = 0.006
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
VV+ G R GRP P W K + L S R + + L + N++D G
Sbjct: 22063 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 22120
Query: 231 YTCLVVNGSGKASMSAELSI 250
YT V N SG S++ + +
Sbjct: 22121 YTLTVENNSGSKSITFTVKV 22140
Score = 42.0 bits (97), Expect = 0.006
Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639
+ LA+NA G +S + T + + EY AP K L G DL + GS
Sbjct: 22709 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22759
Query: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
+ + V G P P++IW E+ E + G + + I+ D+G YT N
Sbjct: 22760 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22819
Query: 700 SAGEVRTQAVLTVQEPHDGTQP 721
++G T+AV + + D P
Sbjct: 22820 ASG---TKAVSVMVKVLDSPGP 22838
Score = 42.0 bits (97), Expect = 0.006
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
T D ++ P E + G+ V ++ G + G+P+P++ W KG+
Sbjct: 22731 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22780
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
L +VS+ I ++ D G YT V N SG ++S + + LDS
Sbjct: 22781 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22835
Score = 41.6 bits (96), Expect = 0.007
Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
+N+ + E TA FE V + P + W +NG I +F + ++G L+I
Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899
Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
ED +YT N + +TV E+TV EG K L
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959
Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
V K+ GD F A + +++ E +F +
Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
+ V E + F C+++ P V W+K + LQ + R+ + ++ + L I D
Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078
Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
G YT + +G +A+L ++G D RS +E +
Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3111
Score = 41.6 bits (96), Expect = 0.007
Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V + Q + CE++ + +V W +G V + G I L + A D+GT
Sbjct: 4919 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 4976
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+ T NA L CS ++V V + ++D V + C + P
Sbjct: 4977 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 5030
Query: 545 ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
I W + +P + L I++A+PED Y E A +T
Sbjct: 5031 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 5086
Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
+ E R+ E L P+ D+ + + + ++S P W
Sbjct: 5087 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 5127
Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
G ++ S + G + L + +V + G +A N+ T A+LTV+E
Sbjct: 5128 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 5179
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
+ F + VT + C + + V W + G + K + F+++ + L
Sbjct: 5180 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 5236
Query: 780 VLKKVQPWHAGQY 792
V+ Q G Y
Sbjct: 5237 VINDSQFDDEGVY 5249
Score = 41.6 bits (96), Expect = 0.007
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6217
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1862
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6218 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6265
Score = 41.6 bits (96), Expect = 0.007
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
A+ ISK S S P + + E P + P+ + + G T + E V G P P +
Sbjct: 17295 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17352
Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
W R + I R C I+ T L++ D G+Y A+N +G++ V +
Sbjct: 17353 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17408
Query: 122 TV 123
V
Sbjct: 17409 KV 17410
Score = 41.6 bits (96), Expect = 0.007
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++VK G + GRP P V W K + L+ A V ++ L I N++D G
Sbjct: 19891 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19948
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
YT + N AS++ L ++ LD+ T T DV KE
Sbjct: 19949 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19987
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+K ++++ + V G P P V WF +G + ++ ++E+ + GS L + A G
Sbjct: 21665 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 21723
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514
Y+ A NA G ++V+ V P
Sbjct: 21724 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 21753
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1813
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 27022 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27080
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
+LII DV D YT N G + T + + ++
Sbjct: 27081 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27118
Score = 41.2 bits (95), Expect = 0.010
Identities = 24/96 (25%), Positives = 43/96 (44%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+C P + ++V EG+ P P V+W K ++ S R+++ +
Sbjct: 8079 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8138
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
LE+ + D G+YT + N G A+ S + + GL
Sbjct: 8139 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8174
Score = 41.2 bits (95), Expect = 0.010
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Query: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570
P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L +
Sbjct: 8082 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 8141
Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTV 600
++ D G YT EN LG + S V V
Sbjct: 8142 PKSVRADAGIYTITLENKLGSATASINVKV 8171
Score = 41.2 bits (95), Expect = 0.010
Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%)
Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454
VSK + P + QR P + K + EV+E V ++ G+P P + WF P
Sbjct: 9794 VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 9850
Query: 455 RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
++ + V D + L C L ++R D+G Y+ TA N G S L V
Sbjct: 9851 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9910
Query: 507 LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557
V P F SV D + +G + + R TW+ ++ +P
Sbjct: 9911 RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 9966
Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
C + +L L + +A+N G + + + ++ + +P AP
Sbjct: 9967 -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 10015
Query: 618 SKPT 621
KPT
Sbjct: 10016 DKPT 10019
Score = 41.2 bits (95), Expect = 0.010
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11210 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11268
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIV 1848
D +Y N+ G T L V
Sbjct: 11269 LRRDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 41.2 bits (95), Expect = 0.010
Identities = 23/80 (28%), Positives = 36/80 (45%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+ G++ ++ I G P P V W +DGK L + E+ TLV+K
Sbjct: 18412 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18471
Query: 790 GQYEILLKNRVGECSCQVSL 809
GQY + L N G S +++
Sbjct: 18472 GQYILKLSNVGGTKSIPITV 18491
Score = 41.2 bits (95), Expect = 0.010
Identities = 26/85 (30%), Positives = 34/85 (40%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V + G L+L V P IIWT K L + + L G + I+ D G
Sbjct: 22752 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22811
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191
Y KN +G S V V D+P
Sbjct: 22812 KYTLTVKNASGTKAVSVMVKVLDSP 22836
Score = 40.8 bits (94), Expect = 0.012
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Query: 604 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W
Sbjct: 7366 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7425
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+++ + E + ++ I + DTGTY EA N G R AV+ V
Sbjct: 7426 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7473
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 7390 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7448
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIV 1848
D Y +AVN G AT E+ V
Sbjct: 7449 KRSDTGTYIIEAVNVCGRATAVVEVNV 7475
Score = 40.8 bits (94), Expect = 0.012
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389
P PP + I ++ L W DGGS + +Y +E D K W+ + T + T
Sbjct: 7779 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7837
Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSE 1414
V L Y FRV A N G S+
Sbjct: 7838 TVTPLTEGSLYVFRVAAENAIGQSD 7862
Score = 40.8 bits (94), Expect = 0.012
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P IL P + IK G + E V G P P W + + + + + L+
Sbjct: 12594 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12652
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I V +D G Y+ A N SG +++ V
Sbjct: 12653 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12683
Score = 40.8 bits (94), Expect = 0.012
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%)
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
++ +A N +G +S L V +A + + P+F + V+ G+D + G P
Sbjct: 15813 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 15871
Query: 543 PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
P +TW + P+ Q R E+ + L I+DA ED G Y N+ G+ + V
Sbjct: 15872 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 15931
Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPI 624
V +K P PT P+
Sbjct: 15932 VLDK-------------PGPPTGPV 15943
Score = 40.8 bits (94), Expect = 0.012
Identities = 20/81 (24%), Positives = 39/81 (48%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G
Sbjct: 16248 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16307
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y N +G+ S++ + +
Sbjct: 16308 NYILKAKNVAGERSVTVNVKV 16328
Score = 40.8 bits (94), Expect = 0.012
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+
Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16994
Query: 104 YTCEATNGSGARQVTVEL 121
Y N G + ++E+
Sbjct: 16995 YGITVANVVGQKTASIEI 17012
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 18005 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 18063
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I + DD KYT A NS G AT +IV
Sbjct: 18064 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/74 (31%), Positives = 33/74 (44%)
Query: 639 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
Q+ + V G P V W +G ++E+ + T SL I+E ED GTY
Sbjct: 19106 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 19165
Query: 699 NSAGEVRTQAVLTV 712
NSAG + + V
Sbjct: 19166 NSAGSITVPITIIV 19179
Score = 40.8 bits (94), Expect = 0.012
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)
Query: 711 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757
+V EP + T P + PR + G+ + I+ IAG P P + W +D
Sbjct: 19462 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19521
Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
G + ++ E++ ++ L +K GQY + LKN G S V+
Sbjct: 19522 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19571
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 5982 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 6039
Query: 1820 DVCGDDDAKYTCKA 1833
D +D YTC A
Sbjct: 6040 DCTPEDIKTYTCDA 6053
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ ++ G T + RV+G PEP +TW + G+ + R L + L I D
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11671
Query: 102 GKYTCEATNGSGARQ 116
GKY A N SG Q
Sbjct: 11672 GKYIISAKNSSGHAQ 11686
Score = 40.4 bits (93), Expect = 0.016
Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V+ QT++ V G P+P++ W EG + R E +++ +D L + +A D G
Sbjct: 11615 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 11673
Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
Y +A N+ G S + V + L V V ++ + + G + V
Sbjct: 11674 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 11733
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596
+P Q S + V + I+ + L + + AEN +G
Sbjct: 11734 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 11777
Query: 597 WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650
T+ K +L + P +P P +L + D + + ++ G
Sbjct: 11778 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 11825
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705
P + H ++ S+D+ +G+ + + + + N GE V+
Sbjct: 11826 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 11883
Query: 706 TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763
T+ V+ + D +P K V T G ++ + + G PFP V W +D A
Sbjct: 11884 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11940
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
+ ++ D L K + G+Y + N G
Sbjct: 11941 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11978
Score = 40.4 bits (93), Expect = 0.016
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
VK V V G P P V+W +GT ++ EG I++ L L +DSG
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 13060
Query: 485 YSCTASNAQGQLSCSWTLQV 504
Y+ TA N+ G S + L+V
Sbjct: 13061 YTITAENSSGSKSATIKLKV 13080
Score = 40.4 bits (93), Expect = 0.016
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%)
Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
S++ G ++ +++ R+++ P F + V G+ F L+ V G P+P I WL
Sbjct: 17303 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 17356
Query: 550 NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
+ I+ + + CE A L ++DA+ D G Y A N G S V V ++
Sbjct: 17357 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 17413
Query: 606 SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633
P P P+ + G++ K
Sbjct: 17414 -----------PGPPEGPVQVTGVTSEK 17430
Score = 40.0 bits (92), Expect = 0.021
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)
Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
DP+ V L E P IL R IK G T + ++G P P+VTW + +
Sbjct: 10894 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10953
Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ R +D G+ + +A H ED G Y+ N +G++ V+V++ V
Sbjct: 10954 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 11001
Score = 40.0 bits (92), Expect = 0.021
Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
VK T++ V G P PEVAW + T + R +++ A S L KA+ D
Sbjct: 11908 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 11966
Query: 483 GTYSCTASNAQGQLSCSWTLQV 504
G Y TA+N G T+ V
Sbjct: 11967 GKYVVTATNTAGSFVAYATVNV 11988
Score = 40.0 bits (92), Expect = 0.021
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)
Query: 598 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
V V+EK S +P VA P S V G + + V +SG P P + W
Sbjct: 16899 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16958
Query: 657 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715
+G ++++ + +L I+E +D G Y N G+ + ++T+ +P
Sbjct: 16959 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 17018
Score = 40.0 bits (92), Expect = 0.021
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575
KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D +
Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18468
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
D G Y N G S V V ++ P P P+ + G++
Sbjct: 18469 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18510
Score = 40.0 bits (92), Expect = 0.021
Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%)
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Q+ V+ +++ G P P W P +++ L +
Sbjct: 22060 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 22116
Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
D+G Y+ T N G S ++T++V + +V ++++ D +++G +
Sbjct: 22117 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 22176
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
V R +W Q C + +++ LAE
Sbjct: 22177 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 22216
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
SA V+E E P+ ++ AP L V+D S+ + +
Sbjct: 22217 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 22260
Query: 654 VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700
WL H+G Q+ DF E T Q + ++ + + + +A N
Sbjct: 22261 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 22318
Query: 701 AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
AG + + ++EP + T + +T G I I+G P P V W
Sbjct: 22319 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 22378
Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
+ L K+T + +D TL +K +G+Y + L+N G + V++++
Sbjct: 22379 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 22437
Query: 817 RAL-PRGREPASCED-LCGGGVGADGGGSD 844
P S E + G DGGG++
Sbjct: 22438 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22467
Score = 39.7 bits (91), Expect = 0.028
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103
G AKF ++ P + W + G+ I + C IR + SL I D G+
Sbjct: 4543 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4598
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
YTC+A+N G+ T LTV G+ V K L +R P E
Sbjct: 4599 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4641
Score = 39.7 bits (91), Expect = 0.028
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 1737 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 5686 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5744
Query: 1791 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5745 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5784
Score = 39.7 bits (91), Expect = 0.028
Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)
Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
PSR + ++ EAP L + L +K G + V G PEP++TW + +
Sbjct: 7367 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7426
Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
R ++ + ++ I D G Y EA N G VE+ V
Sbjct: 7427 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7475
Score = 39.7 bits (91), Expect = 0.028
Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V E + + +P P V+W +G V+ + + + D S +L + K+ D+G
Sbjct: 8093 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 8151
Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
Y+ T N G + S ++V + + ++ S + + +G +L +
Sbjct: 8152 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 8211
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
R T++ P+ + V +D +P + A N +G
Sbjct: 8212 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 8255
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
E PV P P D++V + + MT+ + PP L
Sbjct: 8256 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 8299
Query: 658 HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712
++G +G + C + + P TYT + E VR + +
Sbjct: 8300 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 8357
Query: 713 QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
EP T P P S+ G + + +I+G P+PT+ W++D
Sbjct: 8358 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 8411
Score = 39.7 bits (91), Expect = 0.028
Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L I+ G GR G P+P+V+W ++ + R + T +L D
Sbjct: 10523 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10581
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
GKY N +G+R+ ++ V + G PV + F + W
Sbjct: 10582 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 10633
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221
+K+ ++++ ++G+ V + + + +VS + + IH
Sbjct: 10634 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10682
Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273
N G+ LV + SM A+ + D+ ++ V E ++ D K
Sbjct: 10683 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 10735
Query: 274 EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317
+TN I ++ + S A +K+ C R + P PP
Sbjct: 10736 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 10795
Query: 318 RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373
+ +K K SP P+ S +T Q R + G V G+E R
Sbjct: 10796 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 10855
Query: 374 PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420
A P + P T+ G +D K + G+ D A K +P
Sbjct: 10856 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 10915
Query: 421 -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
+ Q +K T++ + G+P P+V W E + I+V GS L +
Sbjct: 10916 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 10972
Query: 476 KARTRDSGTYSCTASNAQGQLSCS 499
A D G YS T N G + S
Sbjct: 10973 NAAHEDGGIYSLTVENPAGSKTVS 10996
Score = 39.7 bits (91), Expect = 0.028
Identities = 23/81 (28%), Positives = 34/81 (41%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VVK G RF I G P P W ++ +V N VL I + D G
Sbjct: 11215 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11274
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y V N +G +++ L++
Sbjct: 11275 EYQITVSNAAGSKTVAVHLTV 11295
Score = 39.7 bits (91), Expect = 0.028
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
+++ A + + + P V EAP L + + ++ G +A+ +G P
Sbjct: 17688 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17747
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P++TW R T + ++ G+ T L I D GKY + N SG++ V
Sbjct: 17748 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17804
Query: 121 LTV 123
+ V
Sbjct: 17805 VKV 17807
Score = 39.7 bits (91), Expect = 0.028
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V + G L L VS PP I W+ G L + I ++ SL + ++K D G
Sbjct: 23151 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23208
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191
Y A+N +G+ + V V D P
Sbjct: 23209 KYTIEAENQSGKKSATVLVKVYDTP 23233
Score = 39.3 bits (90), Expect = 0.036
Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779
P F +SV G + I+G P P V W RDG+ + T ++ ++ L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839
+ V ++G+Y + N G+ + L+++ +A P + L +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116
Query: 840 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893
G R G P + DG +++ L ++ E
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 894 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953
++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D
Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231
Query: 954 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005
RS+ + G + +P K PP P P RS + K +L + S
Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287
Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032
S P+ + + P PV + PA
Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310
Score = 39.3 bits (90), Expect = 0.036
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 8071 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8130
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
D + L + D YT N LG AT + + V
Sbjct: 8131 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8171
Score = 39.3 bits (90), Expect = 0.036
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)
Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575
SV ++ G+ + V G PVP W + R + +EL I+DAL
Sbjct: 8804 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8863
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
+DHG Y A N+ G +A V V + +L + P + L SD +
Sbjct: 8864 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8918
Query: 636 DGSQVT 641
GS++T
Sbjct: 8919 GGSEIT 8924
Score = 39.3 bits (90), Expect = 0.036
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785
G + I I G P P W DGKA KD H E +N V +++ + +
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9577
Query: 786 PWHAGQYEILLKNRVGE--CSCQVSLM 810
H G+Y I KN+ G+ +C+V +M
Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVM 9604
Score = 39.3 bits (90), Expect = 0.036
Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 668 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
D HFE G H + + G ++ E S G + + V P P +
Sbjct: 16190 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16246
Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
++ G+S + I G P PT+ W++ + L +T E+ + +L +K
Sbjct: 16247 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16302
Query: 786 PWHAGQYEILLKNRVGECSCQVSL 809
+G Y + KN GE S V++
Sbjct: 16303 RVDSGNYILKAKNVAGERSVTVNV 16326
Score = 38.9 bits (89), Expect = 0.047
Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809
A+E P ++D+ V G A+F C ++ +V W + I ES ++
Sbjct: 3481 AKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESE--RLKQS 3538
Query: 1810 EDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
++GN L I +V D Y+C N GE T +A L VE E
Sbjct: 3539 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPE 3583
Score = 38.9 bits (89), Expect = 0.047
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ V G + + +V G P P++ W G + + Q + L I+E D G
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672
Query: 692 TYTCEAWNSAGEVRTQAVLTV 712
Y A NS+G + A++ V
Sbjct: 11673 KYIISAKNSSGHAQGSAIVNV 11693
Score = 38.9 bits (89), Expect = 0.047
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
SV A G+ V + G P PTV W +D K L D + + + L + +V
Sbjct: 20975 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 21033
Query: 789 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
G+Y + ++N VGE SS ++ PA+C+ L
Sbjct: 21034 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 21067
Score = 38.9 bits (89), Expect = 0.047
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584
G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT +
Sbjct: 21273 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21332
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
+NA+ +++ V L P PSKP PI
Sbjct: 21333 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21359
Score = 38.5 bits (88), Expect = 0.062
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
G E+ T + PAP P PP ++ ++ V GESV L ++G T TW +
Sbjct: 875 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
QI+ S ++ ++L I A E G +T N+ G+ L V
Sbjct: 933 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 38.5 bits (88), Expect = 0.062
Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 614 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
PV ++P P + + +++M G + + V+G P P +W E+ + +
Sbjct: 8787 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8845
Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
+ GT+ L I++ +D G Y A NS G
Sbjct: 8846 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8878
Score = 38.5 bits (88), Expect = 0.062
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
L +K G T + E VRG P P+V W ++ +T R +D + FSL
Sbjct: 11906 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11963
Query: 99 EDRGKYTCEATNGSGA 114
D GKY ATN +G+
Sbjct: 11964 SDGGKYVVTATNTAGS 11979
Score = 38.5 bits (88), Expect = 0.062
Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%)
Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
IP EG+ D+ K + ++ T++ V G P P++ W +R + G ++
Sbjct: 13384 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 13436
Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515
+ +L D+G Y T N+ G+ + ++V + V E++
Sbjct: 13437 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 13496
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+ V + +I+G ++ V+ R +W + T E + +
Sbjct: 13497 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 13547
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
+ AEN G + + +R + V S+ P+ DLKV
Sbjct: 13548 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 13588
Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691
S+ + ++ G P G+ I DF E+ Q SL +Q + T
Sbjct: 13589 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 13642
Query: 692 ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744
T+ A N GE T + +TV D P K A + + I
Sbjct: 13643 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13701
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
G P P+V W + L DT V + TL++ Q AG+Y I LKN G
Sbjct: 13702 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760
Query: 805 CQVSL 809
+S+
Sbjct: 13761 GTISI 13765
Score = 38.5 bits (88), Expect = 0.062
Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
PAF L + G K + G P P VTWH++ P+ R + L
Sbjct: 15843 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15901
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I ED G Y + TN +G T+ + V G + + D +
Sbjct: 15902 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15956
Query: 153 PSIWGECPPKF 163
WG PPK+
Sbjct: 15957 ---WG--PPKY 15962
Score = 38.5 bits (88), Expect = 0.062
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17327 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17385
Query: 1824 DDDAKYTCKAVNSLG 1838
D +Y +A N G
Sbjct: 17386 IDGGQYILRASNVAG 17400
Score = 38.5 bits (88), Expect = 0.062
Identities = 22/83 (26%), Positives = 37/83 (44%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ K G I+GRP P+VTW + L+ + RVS++ L + + D G
Sbjct: 22352 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22411
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y + N +G + S + + G
Sbjct: 22412 RYFLTLENTAGVKTFSVTVVVIG 22434
Score = 38.1 bits (87), Expect = 0.081
Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)
Query: 541 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
PV W+ +N +PI+ + E GV +P+ A NA+G
Sbjct: 8020 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 8063
Query: 600 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
+ S SE ++ P KPT + D+ V++G ++++ V P P V W
Sbjct: 8064 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 8117
Query: 659 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717
+G E++ S+ + L + + D G YT N G V + P
Sbjct: 8118 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 8175
Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771
P K +T S SC + +P P +H++ + + + T + V+
Sbjct: 8176 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8225
Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
E+ + +K + P + + N+VG
Sbjct: 8226 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8255
Score = 37.7 bits (86), Expect = 0.11
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
Query: 620 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672
PT + L D +KV G V + V+G P P++ W N I++ D
Sbjct: 9090 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 9149
Query: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
+ + L I + ED GTYT A N G V
Sbjct: 9150 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 9181
Score = 37.7 bits (86), Expect = 0.11
Identities = 20/73 (27%), Positives = 33/73 (45%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V++K G+ R ++GRP P + W K L+ +A++ + + L + D G
Sbjct: 15166 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15225
Query: 230 VYTCLVVNGSGKA 242
YT N G A
Sbjct: 15226 AYTLTATNPGGFA 15238
Score = 37.7 bits (86), Expect = 0.11
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
+AP L P+ + + G T E +RG P P V W ++G+ + + R + I+
Sbjct: 18398 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18457
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
T +LV+ D G+Y + +N G + + + + V
Sbjct: 18458 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18493
Score = 37.7 bits (86), Expect = 0.11
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)
Query: 617 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663
PS+ T PI ++ + D+K D G + + ++G P P + W +G EI
Sbjct: 19466 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19525
Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
+E L +++ DTG Y N AG
Sbjct: 19526 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19564
Score = 37.7 bits (86), Expect = 0.11
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
+ G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y
Sbjct: 21665 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21724
Query: 1169 KCVAKNDAGQAECSCQVTVDDAP 1191
AKN +G A+ +V V D P
Sbjct: 21725 TVEAKNASGSAKAEIKVKVQDTP 21747
Score = 37.4 bits (85), Expect = 0.14
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1825
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8865
Query: 1826 DAKYTCKAVNSLGEATCTAELIV 1848
+Y A NS G A + V
Sbjct: 8866 HGRYVITATNSCGSKFAAARVEV 8888
Score = 37.4 bits (85), Expect = 0.14
Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11671
Query: 790 GQYEILLKNRVG 801
G+Y I KN G
Sbjct: 11672 GKYIISAKNSSG 11683
Score = 37.4 bits (85), Expect = 0.14
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584
G + L +V G P+P ++W +G +P + + + + L + +D G YT
Sbjct: 13005 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 13064
Query: 585 AENALGQVSCSAWVTVHEK 603
AEN+ G S + + V +K
Sbjct: 13065 AENSSGSKSATIKLKVLDK 13083
Score = 37.4 bits (85), Expect = 0.14
Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
VDP R+ P + + + G + K + + G P P + W + Q +++ R
Sbjct: 16233 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16284
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ T SL + D G Y +A N +G R VTV + V G V+S
Sbjct: 16285 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16343
Query: 139 TLGDR 143
++
Sbjct: 16344 VTAEK 16348
Score = 37.4 bits (85), Expect = 0.14
Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480
V+ + + G P PE+ W R+EG +V + G +Y L +
Sbjct: 17731 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 17783
Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
D+G Y N+ G S T++V + LAV EV + ++ + +I+G V
Sbjct: 17784 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 17843
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
+ R YA + + +++ + +AEN G
Sbjct: 17844 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 17891
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
V V + + +E P P K T + D SQ + ++ PE
Sbjct: 17892 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 17932
Query: 654 VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703
H+G + +GT+ +C V +G + +A+N G+
Sbjct: 17933 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 17988
Query: 704 VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
+ + D T QP + + G+ + I + G P P + W++DG+ L
Sbjct: 17989 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 18047
Query: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
K T V + L +K+ G+Y + N G + +S+++
Sbjct: 18048 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096
Score = 37.4 bits (85), Expect = 0.14
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 1740 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 19862 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19920
Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 19921 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19971
Score = 37.4 bits (85), Expect = 0.14
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ +
Sbjct: 20177 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20235
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
D G+Y A N SG + + + V G V+S
Sbjct: 20236 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20275
Score = 37.4 bits (85), Expect = 0.14
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y +
Sbjct: 21668 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21726
Query: 795 LLKNRVGECSCQVSLMLQNSSARAL 819
KN G ++ + +Q++ + +
Sbjct: 21727 EAKNASGSAKAEIKVKVQDTPGKVV 21751
Score = 37.0 bits (84), Expect = 0.18
Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)
Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137
+ H G + + P + V V EG+ +C+V+ P + W LNG+
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834
Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195
++ +K + +G + + I D G K A+N G E ++ + S
Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893
Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
+APE RP+ + + + +P T K + + + +KV ES
Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949
Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290
EL K + IT +K RK+ + E + K +E
Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009
Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340
G K+TI L+ E + + +G A + VV KPDP
Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400
WY + IE D W E C ++D+ +
Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101
Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451
V+AIN+ G + Q +L T ++ ++ KD + + + EP V +
Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161
Query: 1452 VTINTEQKVSDFY 1464
E D Y
Sbjct: 2162 YKDGMEVHEGDKY 2174
Score = 37.0 bits (84), Expect = 0.18
Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%)
Query: 935 PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994
P+ V E + K+ Q+ DFRSVL + P P+ P+F GK + +
Sbjct: 1871 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1916
Query: 995 NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054
+T K V K + + K E + + + T + A
Sbjct: 1917 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 1967
Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101
LKS K+E +++ + H T+ EK++ E + T P FK
Sbjct: 1968 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2027
Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152
+++Q V +G + +V P W NG K ++ + E ++
Sbjct: 2028 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2087
Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178
C + I ED A N AG+
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGE 2113
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + VSG PPP V W N NE ++ E S+ I+ G Y+
Sbjct: 10234 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10291
Query: 697 AWNSAGEVRTQAVLTV 712
A N AGE + ++ V
Sbjct: 10292 AKNEAGERKKTIIVDV 10307
Score = 37.0 bits (84), Expect = 0.18
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 1763 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1819
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11608 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11664
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTA 1844
+ D KY A NS G A +A
Sbjct: 11665 EAVRADHGKYIISAKNSSGHAQGSA 11689
Score = 37.0 bits (84), Expect = 0.18
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 1749 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1802
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11882 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11941
Query: 1803 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
++ D + S ++ D KY A N+ G A + V
Sbjct: 11942 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988
Score = 37.0 bits (84), Expect = 0.18
Identities = 22/92 (23%), Positives = 40/92 (43%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + G ++ + V G P P W +E+ S + + L I++V +D+G
Sbjct: 12603 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12662
Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723
Y+ A NS+G + + V + QP F
Sbjct: 12663 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12694
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16703
Query: 1827 AKYTCKAVNSLG 1838
KYT NS G
Sbjct: 16704 GKYTLTLENSSG 16715
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 1758 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20623
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
S++I D + Y K N++G A+ T
Sbjct: 20624 SILIKDADRLNSGCYELKLRNAMGSASAT 20652
Score = 37.0 bits (84), Expect = 0.18
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V + G + I+G+P P + W K + LQ +A V V + + I ++ + G
Sbjct: 20577 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20636
Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254
Y + N G A SA + +Q LD
Sbjct: 20637 CYELKLRNAMGSA--SATIRVQILD 20659
Score = 36.6 bits (83), Expect = 0.23
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)
Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
RF A E R + PK T +VV G+ P+ + W K N PL
Sbjct: 6677 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6736
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ +E+ ++LE + D G Y ++ N GKA L +
Sbjct: 6737 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6781
Score = 36.6 bits (83), Expect = 0.23
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
V+EG KI G P P +TW K P +P + V + N + V L I
Sbjct: 9823 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9881
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
+ D G+YT VN G AS L++ G
Sbjct: 9882 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9910
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586
G L ++G P P++TW + AR ++L I++A ED G Y+ E
Sbjct: 10928 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 10987
Query: 587 NALGQVSCSAWVTVHEK 603
N G + S V V +K
Sbjct: 10988 NPAGSKTVSVKVLVLDK 11004
Score = 36.6 bits (83), Expect = 0.23
Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643
A+N G +S + T + K EY P PT L + G + +
Sbjct: 14045 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 14095
Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
+ + G P P+ W G +I+ S+ T L I+ +D G YT A N G
Sbjct: 14096 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 14155
Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
+TV + P IS + A+L
Sbjct: 14156 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 14186
Score = 36.6 bits (83), Expect = 0.23
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y
Sbjct: 20183 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20242
Query: 694 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725
A NS+G + ++ + P T P IS
Sbjct: 20243 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20275
Score = 36.6 bits (83), Expect = 0.23
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 1743 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22326 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22384
Query: 1800 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22385 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22432
Score = 36.2 bits (82), Expect = 0.31
Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 1076 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128
NC+ G D N K S P + L+DV V G+ C++S +
Sbjct: 5862 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5920
Query: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
+ W L GK L+ + ++ EG + ++++ ED G + AK+
Sbjct: 5921 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5966
Score = 36.2 bits (82), Expect = 0.31
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%)
Query: 438 SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
SG PKP+V+WF + V ++ + + L +KA+ DSG Y N+ G
Sbjct: 10538 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 10596
Query: 498 CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
+ V V P SF V KD VI
Sbjct: 10597 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 10626
Score = 36.2 bits (82), Expect = 0.31
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
++ + G++ + + G P PT+ WLR K + +++ E+ + L++K
Sbjct: 17329 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17387
Query: 789 AGQYEILLKNRVGECSCQVSL 809
GQY + N G S V++
Sbjct: 17388 GGQYILRASNVAGSKSFPVNV 17408
Score = 35.8 bits (81), Expect = 0.40
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P T L V +EG + + IT + V W N + + + L I
Sbjct: 4435 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4492
Query: 221 HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250
VN +D G Y C +N SGK + SA+L++
Sbjct: 4493 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4523
Score = 35.8 bits (81), Expect = 0.40
Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
T S ++ + E ++ +A N G + ++ L V + D P
Sbjct: 9046 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 9090
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
++ R S+ G+ + VK G+ +TG P P++ W K ++
Sbjct: 9091 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 9140
Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
+ VS L I ++D G YT N G + + + S R+
Sbjct: 9141 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9200
Query: 261 VRETKA 266
V + KA
Sbjct: 9201 VTDIKA 9206
Score = 35.8 bits (81), Expect = 0.40
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G +V I G P PT W DG + K H+ V + L +K G+Y+I
Sbjct: 11220 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11278
Query: 795 LLKNRVGECSCQVSL 809
+ N G + V L
Sbjct: 11279 TVSNAAGSKTVAVHL 11293
Score = 35.8 bits (81), Expect = 0.40
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
EAP +L P L IK G T + G P P+ +W + G+ I +
Sbjct: 14069 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14128
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ + +A + D G+YT ATN G + V++TV
Sbjct: 14129 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 14164
Score = 35.8 bits (81), Expect = 0.40
Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584
G + ++ V G P P +TW Q ++ + A L+I + + D G Y
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14834
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
A N +G+V + VH+ P PT PI
Sbjct: 14835 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14861
Score = 35.8 bits (81), Expect = 0.40
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16705
Query: 104 YTCEATNGSGARQVTVELTV 123
YT N SG + V + V
Sbjct: 16706 YTLTLENSSGTKSAFVTVRV 16725
Score = 35.8 bits (81), Expect = 0.40
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P+ LP +K K + +G P+ V W ++GQ + R + + SL
Sbjct: 19090 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSS-KTVTSLS 19148
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I +ED G Y +N +G+ +TV +T+
Sbjct: 19149 IKEASKEDVGTYELCVSNSAGS--ITVPITI 19177
Score = 35.8 bits (81), Expect = 0.40
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 1782 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20991 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 21047
Score = 35.8 bits (81), Expect = 0.40
Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)
Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142
+T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + +
Sbjct: 27010 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 27069
Query: 1143 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ L ++ I +D GLY N+ G + + +
Sbjct: 27070 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115
Score = 35.4 bits (80), Expect = 0.52
Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F + L ++ V+E + L C+VS P A +IW + + T + EG + I+
Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6218
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
A ED G Y C R P S +D
Sbjct: 6219 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6237
Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
VK + + I P++ ++ GE E ++ + W + K ++
Sbjct: 6238 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6287
Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
+ V L + A + G Y ++V G+ +A +LTV++K
Sbjct: 6288 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6334
Score = 35.4 bits (80), Expect = 0.52
Identities = 16/82 (19%), Positives = 37/82 (45%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
++ ++ G+ + + +G+P+P+V+W K + R + LE + D
Sbjct: 10522 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10581
Query: 229 GVYTCLVVNGSGKASMSAELSI 250
G Y +V N +G ++++
Sbjct: 10582 GKYCVVVENSTGSRKGFCQVNV 10603
Score = 35.4 bits (80), Expect = 0.52
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)
Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676
KP + L G+ L V G + + V G P PEV W + ++ S + R
Sbjct: 11895 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11952
Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+ + D G Y A N+AG A + V
Sbjct: 11953 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988
Score = 35.4 bits (80), Expect = 0.52
Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)
Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
+ +A+NA G +S + T + K E LP P + + V G
Sbjct: 17288 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17338
Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
+ V G P P + WL EI+ES + + L +++ D G Y A N
Sbjct: 17339 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17398
Query: 701 AG 702
AG
Sbjct: 17399 AG 17400
Score = 35.4 bits (80), Expect = 0.52
Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ +K G K + G P P ++W ++G I R + T L + D
Sbjct: 19494 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19552
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
G+Y N +G R V V V G ++ ++ S P + I
Sbjct: 19553 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19612
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205
K T + EG++ SCK+T LKGN + +P
Sbjct: 19613 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 19665
Query: 206 RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
V++ + V LEI V ++ + + C S S + I+ + +
Sbjct: 19666 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 19723
Query: 260 FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314
+VR K D+R + T + E ++ + AA S S R P + P
Sbjct: 19724 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 19779
Query: 315 QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373
PP + K+ +S K + A P+ + + + + S G E
Sbjct: 19780 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 19839
Query: 374 PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
A + R +G+ D S +++ +I E + + F ++ VK +
Sbjct: 19840 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19898
Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
G P P V W T +R + ++ + S L + A DSG Y+ T
Sbjct: 19899 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 19955
Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526
N S + ++V + V K+ AV+
Sbjct: 19956 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 19991
Score = 35.4 bits (80), Expect = 0.52
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V++G + R + I G+P P W K + A ++ SE + L I ++ D G
Sbjct: 23841 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23898
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y ++ N GK ++ ++ + G
Sbjct: 23899 TYDLVLENKCGKKAVYIKVRVIG 23921
Score = 35.4 bits (80), Expect = 0.52
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1816
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 26069 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26126
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
I D DD Y N GEA+ A L V
Sbjct: 26127 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158
Score = 35.0 bits (79), Expect = 0.68
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5537 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5594
Query: 1820 DVCGDDDAKYTCKA 1833
+D+AKY +A
Sbjct: 5595 SAAFEDEAKYMFEA 5608
Score = 35.0 bits (79), Expect = 0.68
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
R+VV G + R ++G+P P VTW L A + + + V I +
Sbjct: 10228 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10285
Query: 229 GVYTCLVVNGSGK 241
GVY+ L N +G+
Sbjct: 10286 GVYSLLAKNEAGE 10298
Score = 35.0 bits (79), Expect = 0.68
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
++ G + VRG P P+VTW + G + G L+D LVI +D
Sbjct: 12313 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12368
Query: 102 GKYTCEATNGSGARQVTVELTV 123
GKY+ N +G + V V + V
Sbjct: 12369 GKYSLTLVNPAGEKAVFVNVRV 12390
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 13058
Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
YT A NS G + T +L V
Sbjct: 13059 GDYTITAENSSGSKSATIKLKV 13080
Score = 35.0 bits (79), Expect = 0.68
Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 615 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
VA AP + L+GL DL + + S + + + G P P V W + +
Sbjct: 13667 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13726
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721
E +L + + D G YT N AG + T ++ V +P T P
Sbjct: 13727 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13777
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
D + AP + P+I K G +V + I G+P P+ +W K +
Sbjct: 14066 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 14115
Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
+PS ++ +L I + D G YT N G
Sbjct: 14116 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14154
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
+V G ++ + I+G P P V RDG L K T F + T+ LK+
Sbjct: 20180 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20238
Query: 789 AGQYEILLKNRVGECSCQVSLML 811
AG+YEI N G +++++
Sbjct: 20239 AGRYEITAANSSGTTKAFINIVV 20261
Score = 35.0 bits (79), Expect = 0.68
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565
V+++ ++ V+K A G L+ + G P P I W + + +Q C +
Sbjct: 20566 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 20622
Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
A + I+DA + G Y NA+G S + V + +K
Sbjct: 20623 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20660
Score = 34.7 bits (78), Expect = 0.89
Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%)
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
V P+ W G PV + + E+ G Y Y A N QG
Sbjct: 7319 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 7365
Query: 497 SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553
S T +++ + E F V L V G L +V G P P+ITW
Sbjct: 7366 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7425
Query: 554 I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
+ Q R T E + + I D+ D GTY A N G+ + V V +K
Sbjct: 7426 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7478
Score = 34.7 bits (78), Expect = 0.89
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + G P P + W+ E+ + + SL +++ D+G Y +
Sbjct: 16253 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16312
Query: 697 AWNSAGE 703
A N AGE
Sbjct: 16313 AKNVAGE 16319
Score = 34.7 bits (78), Expect = 0.89
Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%)
Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451
+SK ++ P+ + + P+ P+ ++ V +T + +V G P P + W L G
Sbjct: 17299 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 17357
Query: 452 TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
+ E+ L + A D G Y ASN G S
Sbjct: 17358 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 17403
Score = 34.7 bits (78), Expect = 0.89
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ AT + ++G PEP+V W + +T + + +F+ LVI V D G
Sbjct: 18814 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18869
Query: 103 KYTCEATNGSGARQVTVELTV 123
+Y N SG++ V + V
Sbjct: 18870 RYNLTLENNSGSKTAFVNVRV 18890
Score = 34.7 bits (78), Expect = 0.89
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 19088 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19146
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I + +D Y NS G T +IV
Sbjct: 19147 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19179
Score = 34.3 bits (77), Expect = 1.2
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6341 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6398
Query: 1824 DDDAKYTCKAVNSLGE-ATCTAELIVE 1849
DD A Y N GE A LIVE
Sbjct: 6399 DDQANYNVSLTNHRGENVKSAANLIVE 6425
Score = 34.3 bits (77), Expect = 1.2
Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%)
Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470
+A PK ++ Q V + + PK E WF E P+ + +I+ + S
Sbjct: 6692 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 6748
Query: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523
+L+A+ D G Y N G+ L+ V L V E S+ +
Sbjct: 6749 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 6807
Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLL 549
+ +G ++ V + R TW+L
Sbjct: 6808 PLTDGGSKIIGYVVERRDIKRKTWVL 6833
Score = 34.3 bits (77), Expect = 1.2
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
G+ L S +K +S DPS + PLT AF+ P +L K+G +
Sbjct: 7054 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 7111
Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
GYP P TW + + +G R + + LVI D+G YT + N
Sbjct: 7112 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 7166
Score = 34.3 bits (77), Expect = 1.2
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
G + VK G R + G+P P+V W K L S RV + + + +
Sbjct: 11904 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11963
Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250
D G Y N +G A +++
Sbjct: 11964 SDGGKYVVTATNTAGSFVAYATVNV 11988
Score = 34.3 bits (77), Expect = 1.2
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 1761 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17723 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17778
Query: 1821 VCGDDDA-KYTCKAVNSLG 1838
C +DA KY K NS G
Sbjct: 17779 NCDRNDAGKYILKLENSSG 17797
Score = 34.3 bits (77), Expect = 1.2
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
P V + E P + L R + +++G + ++G P P W + GQ I+
Sbjct: 23817 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23874
Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
R ++ T LVI D G Y N G + V +++ V GS
Sbjct: 23875 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23922
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+ G + I ++G P PTV W + + L ++ + ++V+K Q H
Sbjct: 10229 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10285
Query: 790 GQYEILLKNRVGE 802
G Y +L KN GE
Sbjct: 10286 GVYSLLAKNEAGE 10298
Score = 33.9 bits (76), Expect = 1.5
Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%)
Query: 537 VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
+RG PVP W +G I ++ + + L I++ L D G Y NA G +
Sbjct: 11229 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11288
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
+ +TV + P PT PI ++D + MT +S PP +
Sbjct: 11289 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 11325
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15229
Query: 1832 KAVNSLGEA 1840
A N G A
Sbjct: 15230 TATNPGGFA 15238
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)
Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
+P+ V P E +LPP + + I+ T + ++G P P+V W R+
Sbjct: 15536 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15593
Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
G L I T S L++ V+ D GKY N SG++ V + V
Sbjct: 15594 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15643
Score = 33.9 bits (76), Expect = 1.5
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + G + + V + G P PEV W EI+++ T SL + V D+G
Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16704
Query: 692 TYTCEAWNSAG 702
YT NS+G
Sbjct: 16705 KYTLTLENSSG 16715
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
+++ P V + +T E +P + ++ G E +G P+P ++W ++G P+
Sbjct: 21242 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21301
Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
F+ +L I +E GKYT N ++ V +TV
Sbjct: 21302 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21346
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 1745 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1794
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 23123 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23177
Query: 1795 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 23178 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23224
Score = 33.5 bits (75), Expect = 2.0
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5271 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5328
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+V DD ++ + + E + TA+L V
Sbjct: 5329 EVTLDDISQIKAQ----VKELSSTAQLKV 5353
Score = 33.5 bits (75), Expect = 2.0
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5626 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5683
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCT 1843
D+ DD ++ +A+ EA T
Sbjct: 5684 DLSIDDTSQIRVEAMGMSSEAKLT 5707
Score = 33.5 bits (75), Expect = 2.0
Identities = 20/72 (27%), Positives = 32/72 (44%)
Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
TG P+P TW G+ L+ RV + + L I + D G+YT + N S
Sbjct: 7114 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7173
Query: 245 SAELSIQGLDSA 256
++++ SA
Sbjct: 7174 EIDVNVIARPSA 7185
Score = 33.5 bits (75), Expect = 2.0
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)
Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
S IS+ ++ DP P L ++ + EG R P P V+WH++
Sbjct: 8067 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 8118
Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
G+ + + R + V +V D G YT N G+ ++ + V G
Sbjct: 8119 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 8173
Score = 33.5 bits (75), Expect = 2.0
Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582
G L+ VRG P P + W + RS A ++ + A D G Y
Sbjct: 11911 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11970
Query: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
A N G A V V +K ++ ++ V+ + T
Sbjct: 11971 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 12009
Score = 33.5 bits (75), Expect = 2.0
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
+ L ++ G T + V+G P P++TW + + R LD I+ T F + V
Sbjct: 13396 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13451
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
++ D GKY N G ++ T+ + V
Sbjct: 13452 NKYDAGKYILTLENSCGKKEYTIVVKV 13478
Score = 33.5 bits (75), Expect = 2.0
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
VK V S S S DP E P F + + L +K GA+ RG P
Sbjct: 19852 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19909
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P V W + + + R +D T SL I + D GKYT N A +T+
Sbjct: 19910 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19966
Query: 121 LTV 123
+ V
Sbjct: 19967 VKV 19969
Score = 33.5 bits (75), Expect = 2.0
Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572
S + K V G F + RG PVP + W +P R+ + L I++
Sbjct: 19885 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19941
Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTV 600
A D G YT +N L S + V V
Sbjct: 19942 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19969
Score = 33.5 bits (75), Expect = 2.0
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G
Sbjct: 19891 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19948
Query: 692 TYTCEAWN 699
YT N
Sbjct: 19949 KYTLTIQN 19956
Score = 33.1 bits (74), Expect = 2.6
Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G KL+ + +LSV+ ++ I R+L E FE + +
Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W+ + I ++ ++ + + L + + ++D GKYT A G + +L
Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
TV G +SK L D+ V E Q F
Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C++ P + WL+ L + + + L I DD+G YT V
Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653
Query: 242 ASMSAE 247
A + E
Sbjct: 2654 AKLKVE 2659
Score = 33.1 bits (74), Expect = 2.6
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 1725 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1770
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 5311 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5370
Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 5371 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5427
Query: 1831 CKAVNSLGEATCTAE 1845
C +A T E
Sbjct: 5428 CDCGTDKTKANVTVE 5442
Score = 33.1 bits (74), Expect = 2.6
Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%)
Query: 442 KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501
K EV W L V Q ++ + H L + + RD G Y A + + +
Sbjct: 6634 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 6690
Query: 502 LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561
+ AP + +D V G+ + P W +P+
Sbjct: 6691 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 6742
Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQ 591
A I +A D G Y + +N G+
Sbjct: 6743 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6772
Score = 33.1 bits (74), Expect = 2.6
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160
+ V G+ + + V+ P I W+ N + K T + +++E + +SI KA
Sbjct: 9103 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 9162
Query: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
+ ED+G Y A N G + V V D P+
Sbjct: 9163 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9194
Score = 33.1 bits (74), Expect = 2.6
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10921 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10977
Query: 1825 DDAKYTCKAVNSLGEATCTAELIV 1848
D Y+ N G T + +++V
Sbjct: 10978 DGGIYSLTVENPAGSKTVSVKVLV 11001
Score = 33.1 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575
+D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D +
Sbjct: 19491 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19549
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
D G Y +N G S + V +K P P P+ + GL+
Sbjct: 19550 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19591
Score = 33.1 bits (74), Expect = 2.6
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ GA+ + +G P P W + ++ D +FS L + + D G
Sbjct: 22064 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 22119
Query: 103 KYTCEATNGSGARQVTVELTV 123
KYT N SG++ +T + V
Sbjct: 22120 KYTLTVENNSGSKSITFTVKV 22140
Score = 32.7 bits (73), Expect = 3.4
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 1824 DDDAKYTCKAVNSLGEAT 1841
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 3.4
Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163
G ++ + + P W +GK K K + L + + I +
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9579
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
G Y AKN AGQ +C+V V D P
Sbjct: 9580 HTGKYSITAKNKAGQKTANCRVKVMDVP 9607
Score = 32.7 bits (73), Expect = 3.4
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1830
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22757 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22814
Query: 1831 CKAVNSLG 1838
N+ G
Sbjct: 22815 LTVKNASG 22822
Score = 32.3 bits (72), Expect = 4.4
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 1765 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6254 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6309
Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
D Y V +G A A L V
Sbjct: 6310 LQDMGTY----VVMVGAARAAAHLTV 6331
Score = 32.3 bits (72), Expect = 4.4
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 614 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
P+ AP + L L + G +T + SG P P+V W + ++ E + H
Sbjct: 10503 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10562
Query: 672 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702
+ T +L ++++ + D+G Y NS G
Sbjct: 10563 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10593
Score = 32.3 bits (72), Expect = 4.4
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575
KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+
Sbjct: 15163 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15221
Query: 576 EDHGTYTCLAENALG 590
D G YT A N G
Sbjct: 15222 RDSGAYTLTATNPGG 15236
Score = 32.3 bits (72), Expect = 4.4
Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584
G + + + G P+P++T +G P++ AE +++++++ D G Y
Sbjct: 20186 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20245
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635
A N+ G + V ++ P PT P+ + +++ V
Sbjct: 20246 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20292
Query: 636 DGSQVT 641
GSQVT
Sbjct: 20293 GGSQVT 20298
Score = 32.3 bits (72), Expect = 4.4
Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
P + L+ +K G+ V + +SG P P + W + E+Q + E S
Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20624
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
+ I++ ++G Y + N+ G A + VQ
Sbjct: 20625 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20656
Score = 32.3 bits (72), Expect = 4.4
Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
+P + + + G + + G P P +W G + R ++ + L I
Sbjct: 23438 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23496
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
D G+YT E N +G T+++ +
Sbjct: 23497 TIRDTGEYTLELKNVTGTTSETIKVII 23523
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 1760 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187
Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ D Y+C V T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)
Query: 1694 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1746
W K G V+ I + S M +I ++ K G+ + + A L + VS +
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
+ + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 1763 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1819
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12306 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12361
Query: 1820 DVCGDDDAKYTCKAVNSLGE 1839
+ DD KY+ VN GE
Sbjct: 12362 NSTRDDSGKYSLTLVNPAGE 12381
Score = 32.0 bits (71), Expect = 5.8
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786
R++ G S+ I I G P P V W +D L K+ + E N + FT L++ +
Sbjct: 14479 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14534
Query: 787 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819
+ G++ + ++N G+ S V++ + ++ L
Sbjct: 14535 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14567
Score = 32.0 bits (71), Expect = 5.8
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18468
Query: 1824 DDDAKYTCKAVN 1835
D +Y K N
Sbjct: 18469 TDGGQYILKLSN 18480
Score = 32.0 bits (71), Expect = 5.8
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
K G+ + + G P P+VTW + R + + +L + D G+Y
Sbjct: 22355 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22413
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
N +G + +V + V G G VS + E+ WGE
Sbjct: 22414 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22465
Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+
Sbjct: 22466 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22518
Score = 31.6 bits (70), Expect = 7.6
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13691 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13749
Query: 1831 CKAVNSLG--EATCTAELI 1847
N G E T + +++
Sbjct: 13750 ITLKNVAGTKEGTISIKVV 13768
Score = 31.6 bits (70), Expect = 7.6
Identities = 19/80 (23%), Positives = 30/80 (37%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V +T ++ G P P+V W +G + +E+ L + D G
Sbjct: 18414 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473
Query: 485 YSCTASNAQGQLSCSWTLQV 504
Y SN G S T++V
Sbjct: 18474 YILKLSNVGGTKSIPITVKV 18493
Score = 31.6 bits (70), Expect = 7.6
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694
G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y
Sbjct: 18417 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18475
Query: 695 CEAWNSAG 702
+ N G
Sbjct: 18476 LKLSNVGG 18483
Score = 31.2 bits (69), Expect = 9.9
Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 1733 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 1779
E L+ E+ ++ E+ EE VK P + D EG
Sbjct: 4397 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4456
Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 1838
I EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G
Sbjct: 4457 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4513
Query: 1839 EATCTAELIV 1848
+ +A+L V
Sbjct: 4514 KTATSAKLTV 4523
Score = 31.2 bits (69), Expect = 9.9
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 1076 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1135
NC+ + T K E A F K Q++ + EG+K C +S + + W +
Sbjct: 6228 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 6283
Query: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
KTL++ + +G + ++ A +D G Y + G A + +TV
Sbjct: 6284 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 6331
Score = 31.2 bits (69), Expect = 9.9
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14479 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14535
Query: 1825 DDAKYTCKAVNSLGE 1839
D K+ N G+
Sbjct: 14536 DTGKFVMTIENPAGK 14550
Score = 31.2 bits (69), Expect = 9.9
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 685
L V G + + V + G P PEV W L N I+ +E F L I E
Sbjct: 14481 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 14532
Query: 686 FPEDTGTYTCEAWNSAGE 703
DTG + N AG+
Sbjct: 14533 NRYDTGKFVMTIENPAGK 14550
Score = 31.2 bits (69), Expect = 9.9
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1830
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14832
Query: 1831 CKAVNSLGE 1839
A N +GE
Sbjct: 14833 LTARNIVGE 14841
Score = 31.2 bits (69), Expect = 9.9
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
+V G++ + ++G P PT+ W +DGK L + T E+ + LV K
Sbjct: 15165 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 15223
Query: 789 AGQYEILLKNRVG 801
+G Y + N G
Sbjct: 15224 SGAYTLTATNPGG 15236
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19491 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19549
Query: 1824 DDDAKYTCKAVNSLG 1838
D +Y N G
Sbjct: 19550 RDTGQYVLTLKNVAG 19564
Score = 31.2 bits (69), Expect = 9.9
Identities = 19/71 (26%), Positives = 30/71 (42%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V V+ G + I+G+P P+VT + VPL+ + R + + + D G
Sbjct: 20181 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20240
Query: 230 VYTCLVVNGSG 240
Y N SG
Sbjct: 20241 RYEITAANSSG 20251
Score = 31.2 bits (69), Expect = 9.9
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1830
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 22067 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 22122
Query: 1831 CKAVNSLGEATCT 1843
N+ G + T
Sbjct: 22123 LTVENNSGSKSIT 22135
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 583
V +G L ++G P P W GQ I + A EL I++A D GTY
Sbjct: 23843 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 23902
Query: 584 LAENALGQ 591
+ EN G+
Sbjct: 23903 VLENKCGK 23910
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 295 bits (755), Expect = 3e-79
Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154
AP FK++L++++V L C+V+ P + W GK + K+ I +G
Sbjct: 24555 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24614
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
+ I +D +Y+ A N G + + V+
Sbjct: 24615 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24648
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
P K +P + +R GE V + +G TW K
Sbjct: 24649 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24692
Query: 1275 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
+ I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP
Sbjct: 24693 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24752
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393
P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V +
Sbjct: 24753 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24811
Query: 1394 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453
L Y+FRV A N +G S+PS+ SE T E + E D+ EV +
Sbjct: 24812 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24868
Query: 1454 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513
++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+
Sbjct: 24869 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24927
Query: 1514 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573
N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E +
Sbjct: 24928 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 24987
Query: 1574 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633
+++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV
Sbjct: 24988 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 25047
Query: 1634 NYEPIGYATDMWSIGVICYIL--------------------------------------- 1654
++ + ATDMWS+G + Y+L
Sbjct: 25048 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 25107
Query: 1655 ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1702
+R+ ++ LQHPWL + + + K + + ++Y +K N V
Sbjct: 25108 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25166
Query: 1703 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1762
+ R+S I +S G + + +E VS + AV EE HVK
Sbjct: 25167 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25214
Query: 1763 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
+ CKIE Y +V W+ + + S ++I Y EDG L + D+
Sbjct: 25215 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25259
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
DD Y CK VN GE + AEL V+ + E
Sbjct: 25260 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25291
Score = 164 bits (416), Expect = 6e-40
Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%)
Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
+VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++
Sbjct: 26376 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26435
Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
+ S K+ Q T+ + A E S P T L
Sbjct: 26436 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26490
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y
Sbjct: 26491 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26550
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285
TC V N +G S S +L+I+ + V K + + V++E++ + ++
Sbjct: 26551 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 26610
Query: 286 DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
EA ++ SK S + S + +K + RT +
Sbjct: 26611 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 26670
Query: 337 VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388
T SI + R+ + G GV + EE + T +Q
Sbjct: 26671 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26728
Query: 389 LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
+ + +SK + + + S P F S+P+SQ + E Q V F CE+SG
Sbjct: 26729 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 26788
Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
P PE+ WF P+ ++ + + L + A DSG Y+ A N +GQ CS
Sbjct: 26789 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 26845
Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560
T + L ++E PS VL+ D LQ S + Q +Q + S
Sbjct: 26846 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 26887
Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613
EA + A + ++ ++ ++S S+++ + S +
Sbjct: 26888 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 26947
Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671
A + P SD+ + +G +T+ +G P PEV W G +I QE FH
Sbjct: 26948 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 27007
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
E +L I +V +D G YT N G
Sbjct: 27008 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 27038
Score = 144 bits (364), Expect = 6e-34
Identities = 102/320 (31%), Positives = 157/320 (49%), Gaps = 23/320 (7%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P+ + Q V+ + +F +SG P+P+++W+ E + + D + L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3251
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526
L++A D+ Y+C A N G + S +L VE V+ P+ + L+D
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311
Query: 527 EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583
EGQ QC V GT + +++W + P ++ R T +L I +A PED GTYT
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370
Query: 584 LAENALGQVSCSAWVTVH------EKKSSRKSEYLLPVAPSKPTA---PIFLQGLSDLKV 634
+A NA+GQVS +A +++ E S+ + L V+ K P F+Q LS L+V
Sbjct: 3371 VASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRV 3430
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHSLCIQEVFPEDTGT 692
+G V +VSG P PE+ W HN I ++D FHFE+ + I + + E G
Sbjct: 3431 HNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQ 3490
Query: 693 YTCEAWNSAGEVRTQAVLTV 712
Y+C+A NSAGE A LTV
Sbjct: 3491 YSCKAANSAGEATCAATLTV 3510
Score = 143 bits (360), Expect = 2e-33
Identities = 126/488 (25%), Positives = 194/488 (39%), Gaps = 100/488 (20%)
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEG-SIEVYEDAGSHYLCLLKART 479
Q E Q +F+C VSG +V+W+ + ++ + +ED ++ L + +A
Sbjct: 3306 QDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED--TYQLEIAEAYP 3362
Query: 480 RDSGTYSCTASNAQGQLSCSWTLQVERLAVMEV----------------------APSFS 517
D GTY+ ASNA GQ+S + L +E + E PSF
Sbjct: 3363 EDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFI 3422
Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAELHIQD 572
L V G+ V G P P I W N Q I + G+A + I D
Sbjct: 3423 QPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVD 3482
Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTV---------HEK-------------------- 603
A E G Y+C A N+ G+ +C+A +TV HE+
Sbjct: 3483 AYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAE 3542
Query: 604 ---------KSSRKSEYL-----LPVAPSK------PTAPIFLQGLSDLKVMDGSQVTMT 643
+ S+ +E L PV P+K T PIF++ +S+ + G T++
Sbjct: 3543 EEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLS 3602
Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
V V G P P++ W NG + S D+ F G HSL I ED G YTC A N G+
Sbjct: 3603 VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGK 3662
Query: 704 VRTQAVLTVQ---EPHDGTQ-----------------PWFISKPRSVTASLGQSVLISCA 743
A L + E H T+ P F+ + + + + G +
Sbjct: 3663 TICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYT 3722
Query: 744 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 803
+ G+P PTV W ++ K LC + + T ++ Q +G Y +N +GE
Sbjct: 3723 VVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGES 3782
Query: 804 SCQVSLML 811
+C L++
Sbjct: 3783 TCAAELLV 3790
Score = 139 bits (349), Expect = 3e-32
Identities = 149/661 (22%), Positives = 246/661 (37%), Gaps = 102/661 (15%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ VA + S +L V+ E P + + + ++ G A+F + G P+
Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221
Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P+++W++ Q +++G + FL D ++L++ ED YTCEA N G +
Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
L+VE P V + PP T L V EGQ R
Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F C+++G +V+W + ++PS +++ LEI +D G YT + N
Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376
Query: 240 GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE---------SKLDSLEA 290
G+ S +A LS++G E +NS ++ KE L SL
Sbjct: 3377 GQVSSTANLSLEGFSKF------EENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRV 3430
Query: 291 AAKSKNCSSPQRGGSP----PWAANSQPQPPRESKLESCKDS------------PRTAPQ 334
+ G P W N Q P + + ++S A Q
Sbjct: 3431 HNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQ 3490
Query: 335 TPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATF-PTRQPGLGSQD 393
S+ AA + P+AP + +E + ++F + GL S +
Sbjct: 3491 YSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAE 3550
Query: 394 VVSKAANRRIPM-----------EGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPK 442
+ N + + + +++ P F + + ++ V GIPK
Sbjct: 3551 LQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPK 3610
Query: 443 PEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL 502
P++ WF G + + D H L +L + D G Y+C ASN G+ CS L
Sbjct: 3611 PKIQWFFNGV-LLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYL 3669
Query: 503 QVE-----------RLAVME--------VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
++ AV + P F LK +G + + +V G P P
Sbjct: 3670 KINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAP 3729
Query: 544 RITWLLNGQ----PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
+TW + + Y G + D ED G Y C AEN LG+ +C+A +
Sbjct: 3730 TVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELL 3789
Query: 600 V 600
V
Sbjct: 3790 V 3790
Score = 134 bits (336), Expect = 1e-30
Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%)
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
S + P + S+ P + Q V + KF + +G P+P W +G +
Sbjct: 26462 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 26521
Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
Q G ++ ED G +L + K T DSG Y+CT N+ G +S S L ++
Sbjct: 26522 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 26570
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+KD E Q Q + TP + ++ + Q A + E ++E Q+ L
Sbjct: 26571 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 26622
Query: 576 -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631
++ + ++E + S + VHE+ K+S+ SE + A K + +
Sbjct: 26623 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 26675
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + +G ++ + ++G +V W+ NG E+ SE++ + G+ +L I++ D G
Sbjct: 26676 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26733
Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
TC + G V+ Q LT+ + P FIS+PRS + GQ+VL +C I+G+P P
Sbjct: 26734 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26792
Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
+ W ++ + + + + ++ +V++L ++ +G+Y I KN G+CS SLM+
Sbjct: 26793 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851
Query: 812 QNSSARALPRGREPA 826
LP EP+
Sbjct: 26852 -------LPLVEEPS 26859
Score = 122 bits (306), Expect = 3e-27
Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++
Sbjct: 23779 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23835
Query: 795 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848
+L+N+ G+ + + + + S P G P +D+ V AD GG+D G
Sbjct: 23836 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23891
Query: 849 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906
+ W + VRG +++ E R Q L + V+
Sbjct: 23892 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 23949
Query: 907 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963
KT L+ + P E +D + + + +V + ++ + K +
Sbjct: 23950 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 24008
Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022
KT + + PD + ++ A+N +ET A + V P G
Sbjct: 24009 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 24064
Query: 1023 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070
L+ + +K + TL KP K D K ++KE +K
Sbjct: 24065 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 24124
Query: 1071 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
+N+ R T + K + G AP +++++DV G+ L CQ
Sbjct: 24125 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24183
Query: 1121 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180
+ P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E
Sbjct: 24184 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24243
Query: 1181 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
S ++ + P P P K
Sbjct: 24244 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24263
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299
E G ++ L G TW +K +Q SE++ +EN+E+ + L +
Sbjct: 24264 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24319
Query: 1300 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG
Sbjct: 24320 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24379
Query: 1360 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P +
Sbjct: 24380 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24439
Query: 1418 ESELTTVGEKPEEP 1431
S + + E+P
Sbjct: 24440 VSSVVIIKSPFEKP 24453
Score = 118 bits (295), Expect = 6e-26
Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)
Query: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680
T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 681 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714
I+E F ED+G +TC A N AG V T L VQ
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 715 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
P + P+FI+KP G SV+ C + G+P P V+W + G
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 760 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ +
Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131
Query: 817 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875
L + ++ + V + G PG+ + + E+E + + K
Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186
Query: 876 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932
V R + E+ QE F + L K++ KT E+ L+E E+M +
Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242
Query: 933 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981
V+ S + ++ + + ++ V S P+P +++ + DF
Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298
Query: 982 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035
R+ L LP + G +A N K NA SG P P+G TL
Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350
Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095
+P+ + +L P ++ + A + + + S+ +
Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407
Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152
P F K EG+ +V P W +G+ + T +++ ++G+
Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467
Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212
S+ I A P D G + VA+N AG++ S +TV+
Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504
Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
+ + P ++ ++ ++ G +E+ + TG W+
Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544
Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327
K I ++ +++E ++ + L I + + YT NK G + + +VN+ V
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604
Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348
+P+P P GT A +I + L
Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631
Score = 115 bits (288), Expect = 4e-25
Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483
+ E Q + + ++G +V W L G + E Y +GS +K A RD G
Sbjct: 26678 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 26733
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
+C + +G + C + L + + + AP+F S + + EGQ+ + C + G P P
Sbjct: 26734 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26791
Query: 544 RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
I W N PI + + V L I++A D G YT A+N GQ S +A + V
Sbjct: 26792 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
LP+ +P+ + L+ D + GS + +VQ+S + +
Sbjct: 26852 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 26897
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
+ + F Q +QE F E + + N ++ + ++ G
Sbjct: 26898 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 26956
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779
P + P ++ G+ + ++CA G+P P V W G+ + ++ G F + +D+ TL
Sbjct: 26957 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 27016
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813
++ VQ G Y + L N G S V++ +++
Sbjct: 27017 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27050
Score = 115 bits (287), Expect = 5e-25
Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
F +++ + EG F CK++G P P++ W K R+ E+ M L+
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1297
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282
G+AS+ + + + +F K N I
Sbjct: 1298 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1330
Query: 283 SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342
KL +E AA G+P + +P S++ S SPR+ ++P+
Sbjct: 1331 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1369
Query: 343 SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402
R+ P +P R PA PA PG ++ R
Sbjct: 1370 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1408
Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
P F KP S + E QT +F +V G P PE WF +G +
Sbjct: 1409 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1459
Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
V ++ G+ L ++ A DSG ++ A N G+ S S L VE + +V P F LK+
Sbjct: 1460 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1518
Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577
+ EG ++ G P P I WL N P +Y + E G A L I + +D
Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578
Query: 578 HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617
YT A N G+ C V V + + + ++P AP
Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1638
Query: 618 -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662
K P F + L+ L++ +++ G+P V WLH+G
Sbjct: 1639 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714
++ + SL + D+G TC A N G T A L V++
Sbjct: 1699 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1758
Query: 715 ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744
H+G +P + P V G++ C +
Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1818
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G
Sbjct: 1819 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1876
Query: 805 CQVSLMLQNSS--ARALPRGREP 825
+V L +Q L R EP
Sbjct: 1877 HKVKLEIQQREDFRSVLRRAPEP 1899
Score = 113 bits (282), Expect = 2e-24
Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
+K S RK E L + AP + +V G + V P EV W HNG
Sbjct: 25981 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 26040
Query: 662 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682
E+QES D H + GT ++C
Sbjct: 26041 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 26100
Query: 683 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718
+ VFPE T T EA +S EV++Q T + H
Sbjct: 26101 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26160
Query: 719 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752
+ ++KPRS+T G+S SC G+P PTV
Sbjct: 26161 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26220
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q
Sbjct: 26221 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26279
Query: 813 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848
+ + ++ R + P +++
Sbjct: 26280 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26339
Query: 849 LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
L P + +L+ E +++ VL+ + T + +++ Q +
Sbjct: 26340 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26399
Query: 901 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954
++ L+E D + EI E + NLQ + K++ E+ K+ ++ D +
Sbjct: 26400 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26459
Query: 955 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983
S + +K K P P P P+P T D ++
Sbjct: 26460 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26519
Query: 984 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015
+ GGK KL + G SS+ L KA++ ++
Sbjct: 26520 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26579
Query: 1016 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067
+ Q + + P A E + A +E +K M AK E L + ASK EE+
Sbjct: 26580 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26636
Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
KK + H T + SE T K + + EG++L+L+ ++
Sbjct: 26637 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26694
Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ W LNG L ++ GS +++I++A D G+ C++K G +C +T+
Sbjct: 26695 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26754
Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247
+ E+ SDA P I P Q
Sbjct: 26755 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26771
Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
+ G++V +++G W K I S ++ + S N L I A G
Sbjct: 26772 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26831
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S
Sbjct: 26832 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26891
Query: 1368 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423
+ S++ + + + S + Q + E + + + G S +Q S++
Sbjct: 26892 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 26949
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEV 1447
G + PK E SD E +V
Sbjct: 26950 AGIRGIPPKIEALPSDISIDEGKV 26973
Score = 112 bits (279), Expect = 4e-24
Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
+N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E
Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
D G YT A+N G + +L VE A LG P TL R +P +R I
Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369
Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
P F K EGQ R
Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429
Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
F K+ GRP P+ W G + V +++G Q L I D G +T + N
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489
Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
+G++S+S L+++ ++ FV + K N I + S+L+ A + N
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538
Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
W NS P + ++E K + V Q
Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592
Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
T + ++ +PEP ++ P G R K A P P Q D+
Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453
K ++ P F+ K S +K F C ++ G P V W +G P
Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698
Query: 454 VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502
+ + + + G L A +RDSG +C A+N G S TL
Sbjct: 1699 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757
Query: 503 -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536
++E L M + + V D V+EG+ +C
Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817
Query: 537 VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594
V G P P++ W LNGQ I+ ++ G+ L I D D G AEN G +
Sbjct: 1818 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1877
Query: 595 SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
+ + +++ R +L AP +P + G +V + T + E
Sbjct: 1878 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1929
Query: 654 VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694
V+ L I +ESE+ F++R + S E + E
Sbjct: 1930 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 1989
Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738
E + E+ + + E T P F + +S T G
Sbjct: 1990 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2049
Query: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
+ G P P W ++G + + + ++V LV++ V + + N
Sbjct: 2050 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2109
Query: 799 RVGECSCQVSLMLQ 812
GE S L++Q
Sbjct: 2110 IAGETSSHAFLLVQ 2123
Score = 111 bits (278), Expect = 6e-24
Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
+PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L
Sbjct: 12526 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12584
Query: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355
I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+
Sbjct: 12585 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12644
Query: 1356 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE
Sbjct: 12645 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12704
Query: 1415 PSQESELTTVGE--KPEEPKD 1433
P ++ P EPK+
Sbjct: 12705 PLTSPKMVAQFPFGVPSEPKN 12725
Score = 110 bits (275), Expect = 1e-23
Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567
AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I + G Y+ A N GQ + +A + V K+E AP P F+Q
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168
Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713
ED+GTY+ A NS G + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 109 bits (272), Expect = 3e-23
Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)
Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58
Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
S L I AV + + G+Y+ +ATNGSG T EL V+ A
Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PP F +L + V++G R ++TG P P V + + +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
+S++ + L I +D G Y+ N G+A+ +AEL +QG
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ +A S R+T+ + + ++ + E +D AA + +P R PP +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263
Query: 312 SQPQPP 317
P PP
Sbjct: 264 RSPTPP 269
Score = 109 bits (272), Expect = 3e-23
Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y
Sbjct: 7330 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7389
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y +
Sbjct: 7390 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7448
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426
E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T +
Sbjct: 7449 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7508
Query: 1427 KPEEPKDEVEVSD 1439
P P +E SD
Sbjct: 7509 DPPGPPTRLEPSD 7521
Score = 106 bits (264), Expect = 2e-22
Identities = 102/414 (24%), Positives = 158/414 (38%), Gaps = 48/414 (11%)
Query: 415 KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
+F + +V E + F CEVS P V W + ++ + I++ ++ H L +
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3070
Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
R D+G Y+ A + +L V S+ K+ VIE Q V++
Sbjct: 3071 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3121
Query: 535 CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
V V W +G I + + E + + I + D G YT +A
Sbjct: 3122 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3178
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
+R S L AP P LQ L + V G +SG
Sbjct: 3179 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3219
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
P P++ W + F G +++L + E FPED YTCEA N G T A
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279
Query: 710 LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
L+V+ P D P + I+ + S GQ C ++G + +D K
Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3337
Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSS 815
K + F + Q ED + L + + P G Y + N VG+ S +L L+ S
Sbjct: 3338 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFS 3391
Score = 102 bits (253), Expect = 5e-21
Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
+++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A
Sbjct: 20504 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20563
Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
+ + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG
Sbjct: 20564 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20623
Query: 1361 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
+ + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP
Sbjct: 20624 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20680
Query: 1417 QESEL 1421
+ +
Sbjct: 20681 ESDSV 20685
Score = 101 bits (252), Expect = 6e-21
Identities = 114/459 (24%), Positives = 183/459 (39%), Gaps = 56/459 (12%)
Query: 384 TRQPGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIP 441
TR G VV+ + ++ +EG RD + + Q E K+ V+F +
Sbjct: 3073 TRMSDAGKYTVVAGGNVSTAKLFVEG-RDVRIRSIKKEVQVIE-KQRAVVEFEVNEDDV- 3129
Query: 442 KPEVAWFLEGTPVRRQEGSIEVYE-DAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
+ W+ +G + Q Y + H + + + R D+G Y+ A G+ S
Sbjct: 3130 --DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA----GRNRSSV 3183
Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA--- 557
TL V P L+ V G+ + G P P+I+W Q +
Sbjct: 3184 TLYVNA----PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3239
Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
+ + L + +A PED YTC A+N G + SA ++V E + +PV P
Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEMPVYP 3298
Query: 618 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 677
P + L D +G +VSG +V W +I+ S F Q
Sbjct: 3299 -----PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDT 3352
Query: 678 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ------------------------ 713
+ L I E +PED GTYT A N+ G+V + A L+++
Sbjct: 3353 YQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKK 3412
Query: 714 EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL--CKD-TGHFEV 770
EP G +P FI S+ G++V ++G P P + W + + + KD HFE
Sbjct: 3413 EPL-GQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFE- 3470
Query: 771 LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
++ + +++ HAGQY N GE +C +L
Sbjct: 3471 -ESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATL 3508
Score = 101 bits (252), Expect = 6e-21
Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)
Query: 1236 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
+PP + ++ E V+AG +V + G T W +I+ EH VE
Sbjct: 11134 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11193
Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352
S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW
Sbjct: 11194 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11253
Query: 1353 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411
DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G
Sbjct: 11254 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11313
Query: 1412 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469
P +S T K P P + V+D E V + + ++ +Y +E R
Sbjct: 11314 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11371
Query: 1470 LGSGKFGQV 1478
+GK+ +V
Sbjct: 11372 EVTGKWVRV 11380
Score = 101 bits (252), Expect = 6e-21
Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++
Sbjct: 16168 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16224
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL
Sbjct: 16225 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16284
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N
Sbjct: 16285 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16344
Query: 1410 YGTSEPSQESELTTVGE--KPEEPK 1432
YG EP + + P+ PK
Sbjct: 16345 YGVGEPLESEPVVAKNPFVVPDAPK 16369
Score = 101 bits (251), Expect = 8e-21
Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)
Query: 1243 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302
F + VRAG S+ LF G T W K + S + +++ S LT+ +
Sbjct: 21991 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 22048
Query: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362
G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+
Sbjct: 22049 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 22107
Query: 1363 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421
+ Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E
Sbjct: 22108 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22167
Query: 1422 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471
E+P P+ D V+ S +P+ D + QK SDF+ +E
Sbjct: 22168 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22226
Query: 1472 SGKFGQVFRLVEK 1484
V RLVEK
Sbjct: 22227 KQLTFTVERLVEK 22239
Score = 100 bits (250), Expect = 1e-20
Identities = 133/588 (22%), Positives = 220/588 (37%), Gaps = 101/588 (17%)
Query: 63 QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119
+V W+ + + S +F L D + T++LVI V+ ED +G+Y CEA N SG +
Sbjct: 4396 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4452
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
+LTV A PV+ + K+ + V G + +
Sbjct: 4453 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4480
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F+C+I P + W K + S + S+ + LEI D G YTC N
Sbjct: 4481 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4540
Query: 240 GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294
G S +A L ++ G + R + E K + ++EV +V+ K + + + K
Sbjct: 4541 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4597
Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
+ P PP P+P E ++ + R P+ + + +I L A +P
Sbjct: 4598 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4651
Query: 355 EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414
+P A + P E P P T P ++ +AA + P++G
Sbjct: 4652 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4710
Query: 415 KFES-----KPQSQEVKENQTVKFRCEVSGIP---------------------------- 441
E+ +P S K F ++ +P
Sbjct: 4711 PIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLV 4770
Query: 442 KPEVA---WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
P A W +G+ + R+ D L ++ + D+G Y+C + +
Sbjct: 4771 SPSTAITTWMKDGSNI-RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTS 4829
Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
+ L VE L V V ++ ++ V++GQ L C + + W +G+ +
Sbjct: 4830 TAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKP 4883
Query: 559 STCEAGV----AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
GV L I DA D GTYT ENA + CS+ V V E
Sbjct: 4884 GRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKVVE 4930
Score = 100 bits (250), Expect = 1e-20
Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L +
Sbjct: 15093 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15152
Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
+ G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG
Sbjct: 15153 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15212
Query: 1361 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
+ + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP +
Sbjct: 15213 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15272
Query: 1420 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471
+ V P+ PK+ EV D P+ D + IN Y +E R
Sbjct: 15273 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15322
Query: 1472 SGKFGQVFRLVEKKT 1486
K GQ + KKT
Sbjct: 15323 -DKAGQRWIKCNKKT 15336
Score = 100 bits (249), Expect = 1e-20
Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y
Sbjct: 15787 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15846
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y +
Sbjct: 15847 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15906
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
E D++ TW+ + AT T+ L EY+FR+ A N YG S
Sbjct: 15907 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 15952
Score = 100 bits (248), Expect = 2e-20
Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)
Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567
V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A
Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623
L I LPED G YT A N G CS + V Y L PV+ + +P
Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362
Query: 624 -------------------------------------------------IFLQGLSDLKV 634
+F+ K
Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481
Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
+T A N AG +LTV+ +P F+ K ++V G + + G+P P +
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541
Query: 753 HWLRD 757
WL++
Sbjct: 1542 VWLKN 1546
Score = 100 bits (248), Expect = 2e-20
Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A++ S +L +V +PL FI P ++ + E AKFE V P+
Sbjct: 5446 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5496
Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
W + Q IT RF L+ G + + + A +E + + E + SG
Sbjct: 5497 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5555
Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
+ VT + F +L + KT F
Sbjct: 5556 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5615
Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
+++ I E P F KL E C+I+ P
Sbjct: 5616 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5675
Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248
V W K ++PS + ++L + + D+G YTC G+ K S ++
Sbjct: 5676 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 5732
Query: 249 ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287
S++ +++ F ET+ + D+ + I +E K+ S
Sbjct: 5733 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 5790
Query: 288 LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341
L NC Q GG AAN + K L KD TA +T
Sbjct: 5791 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 5846
Query: 342 SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395
S L+ +++P + + P E + R + G +
Sbjct: 5847 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 5896
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
+K + + +F + Q V+E T CEVS +V WF GT +
Sbjct: 5897 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 5953
Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
+ + E+ D L + D TY+C A + + SC+ L V+
Sbjct: 5954 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 6003
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572
F L D V E + +C + ++ W +G I+ + + V L I
Sbjct: 6004 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 6062
Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632
L +D Y+C A S +TV E+++ +F + L+++
Sbjct: 6063 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 6100
Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
+V + + + +VS P EVIW EI E+ + G + L IQ ED G
Sbjct: 6101 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6159
Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
Y C +S RT + V E FISKP+++ G+ C+I+ + FP V
Sbjct: 6160 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 6210
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796
W RD K L + ++V+ + LV+K G Y +++
Sbjct: 6211 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 6253
Score = 100 bits (248), Expect = 2e-20
Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288
MPP I E +V G +V + K+ G T TW K ++ + H+
Sbjct: 9744 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9802
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348
++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + +
Sbjct: 9803 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9862
Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407
TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A
Sbjct: 9863 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9922
Query: 1408 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
N YG EP + +PE ++ V + D V ++T+N E+ D
Sbjct: 9923 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 9971
Score = 99.8 bits (247), Expect = 2e-20
Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%)
Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343
E + +K PQR S P +P P E+ +++ ++KT+
Sbjct: 693 ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 750
Query: 344 SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403
T + V PR SP K P G + ++ +A +
Sbjct: 751 LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 796
Query: 404 PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463
E S+ K ++ VK ++T R P P+ F + + E +EV
Sbjct: 797 QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 852
Query: 464 YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523
++ G + + R+ A+ + VE + P+ S LK+
Sbjct: 853 KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 906
Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580
VIEG+ L+C + G P P +TW I+ + + T ++G+A L I++A ED G
Sbjct: 907 TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 966
Query: 581 YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614
+TC A N G VS S ++ V EK+++ +E
Sbjct: 967 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1026
Query: 615 -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671
P +P AP F+ K+++G V QV GNP P V W +G + + +
Sbjct: 1027 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1086
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
++ + L I F +D G YT N GE A L + ++
Sbjct: 1087 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132
Score = 99.4 bits (246), Expect = 3e-20
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++
Sbjct: 17251 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17307
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351
+ L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+
Sbjct: 17308 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17367
Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410
W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y
Sbjct: 17368 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17427
Query: 1411 GTSEPSQES 1419
G EP + +
Sbjct: 17428 GVGEPLESA 17436
Score = 97.8 bits (242), Expect = 9e-20
Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%)
Query: 426 KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+E VK+ C++ + +V W+ + E YED G L + D GT
Sbjct: 25208 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 25266
Query: 485 YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522
Y C N G+ S C T++ + + ++E P F+ L +
Sbjct: 25267 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 25326
Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576
G++ ++ P P +TW +GQ I+ + + G+ +L I +
Sbjct: 25327 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25386
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
D YT +A N G+ SC A +TV L P P+F + L++ + +
Sbjct: 25387 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 25436
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695
G V ++VSG PPP + W +G + + G ++L I++ PEDTG Y
Sbjct: 25437 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25496
Query: 696 EAWNSAGEVRTQAVLTVQ 713
A N+AG QA L V+
Sbjct: 25497 TATNTAGSTSCQAHLQVE 25514
Score = 97.4 bits (241), Expect = 1e-19
Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y
Sbjct: 21203 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21262
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T++++N + + + + P P G +I++ S+ LSW +GG + YSI
Sbjct: 21263 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21322
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 21323 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21370
Score = 97.4 bits (241), Expect = 1e-19
Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI
Sbjct: 26002 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 26061
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278
+ DD G Y + N G+AS A L + G D + R + V E+T
Sbjct: 26062 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 26121
Query: 279 --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
+S K +EA++ + S + + S + ++++S ++ +
Sbjct: 26122 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 26178
Query: 337 VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396
+K +++ AAR+ +PR+ + GE + PT L V+S
Sbjct: 26179 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 26230
Query: 397 KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450
+A ++ + + + S S E V EN K E + I K V
Sbjct: 26231 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 26288
Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509
+P R + V +K+ R S S + + + + T +V+ L V
Sbjct: 26289 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26342
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563
P + LK A + L C V + + +TW +G+ ++ +
Sbjct: 26343 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26399
Query: 564 GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609
G EL I + D G Y C G Q A+ ++HEK KS +K+
Sbjct: 26400 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26459
Query: 610 EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
++P AP + + GL D V S V+ +G P P IW +G
Sbjct: 26460 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26519
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
I + + + L I + D+G YTC NSAG V + LT++ D
Sbjct: 26520 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26574
Score = 96.7 bits (239), Expect = 2e-19
Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12994
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y +
Sbjct: 12995 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 13053
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
+ +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P
Sbjct: 13054 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 13101
Score = 96.7 bits (239), Expect = 2e-19
Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%)
Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
K + I+KTS + + R + E AF + I EG + + G + V
Sbjct: 26646 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26696
Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
W NG +T+ + G+ G+ +L I D G TC + G + +LT+
Sbjct: 26697 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26754
Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
SK L D APA ++P + EGQ F+C+
Sbjct: 26755 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26784
Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S
Sbjct: 26785 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26844
Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
+A L + L V + V+ + S SL+ +++S S+ +
Sbjct: 26845 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26887
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
+ S ++S E K S ++ Q ++ +SSS +
Sbjct: 26888 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26932
Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
G+ + + E S + KA R IP PK E+ P
Sbjct: 26933 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 26964
Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480
+ E + + C +G P PEV W G + QE G + L ++ + +
Sbjct: 26965 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 27024
Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERL 507
D G Y+ + N G S + + + +
Sbjct: 27025 DGGLYTLSLGNEFGSDSATVNIHIRSI 27051
Score = 96.3 bits (238), Expect = 2e-19
Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)
Query: 1228 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
P T PP + + F + +R GE+ L G+ +G +W K + E + +
Sbjct: 10436 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10495
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346
+ + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++
Sbjct: 10496 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10555
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405
+ +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+
Sbjct: 10556 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10615
Query: 1406 AINVYGTSEPSQESELTT-----VGEKPEEP 1431
A N+YG S+P + V + P++P
Sbjct: 10616 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10646
Score = 95.9 bits (237), Expect = 3e-19
Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
+G + + + K P P I D V GE + + T +W K
Sbjct: 7994 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 8050
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P
Sbjct: 8051 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 8110
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392
ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+
Sbjct: 8111 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8169
Query: 1393 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449
DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + +
Sbjct: 8170 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8228
Query: 1450 RTVTINTEQKVSDFYDIEERLGSGK 1474
+ + K+ + I E++ G+
Sbjct: 8229 KPPLYDGGSKIMGY--IIEKIAKGE 8251
Score = 95.9 bits (237), Expect = 3e-19
Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%)
Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561
++A +E+ P ++ EG C + ++TW + ++ + T
Sbjct: 25189 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25247
Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608
E GVA L+++D D GTY C N G+ S A + V KK R+
Sbjct: 25248 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25307
Query: 609 SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
++ + L P + T P++ + G V V ++ +P P V W +G +I+ +
Sbjct: 25308 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25362
Query: 668 D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720
+ + FE + L I V +D YT A N GE +A LTV P D T +
Sbjct: 25363 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25422
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
P F + GQSV ++G P PT+ W +DG+ L + + D + L
Sbjct: 25423 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25482
Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
++ P G Y + N G SCQ L ++
Sbjct: 25483 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25514
Score = 95.5 bits (236), Expect = 4e-19
Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)
Query: 1249 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G
Sbjct: 14018 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14077
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY
Sbjct: 14078 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14136
Query: 1368 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
+E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q +
Sbjct: 14137 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14193
Query: 1424 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
V P P ++ EVS+ V T T++ ++ V D
Sbjct: 14194 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14226
Score = 94.7 bits (234), Expect = 7e-19
Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VRAG S+ +F + G TW K I +EN+E+ + L I + G +
Sbjct: 14416 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14473
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y +
Sbjct: 14474 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14532
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E
Sbjct: 14533 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14592
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478
P P D + + D + + + + K++ + +R GS ++ +
Sbjct: 14593 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14642
Score = 94.7 bits (234), Expect = 7e-19
Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++
Sbjct: 19414 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19470
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L
Sbjct: 19471 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19530
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N
Sbjct: 19531 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19590
Query: 1410 YGTSEP 1415
YG EP
Sbjct: 19591 YGVGEP 19596
Score = 94.4 bits (233), Expect = 9e-19
Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
+RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y
Sbjct: 23086 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23143
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y +
Sbjct: 23144 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23202
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E
Sbjct: 23203 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23262
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
P P ++EV D V TVT+ E+ + D
Sbjct: 23263 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23289
Score = 94.0 bits (232), Expect = 1e-18
Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y
Sbjct: 19034 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19093
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y +
Sbjct: 19094 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19152
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E
Sbjct: 19153 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19210
Query: 1428 PEEP 1431
P P
Sbjct: 19211 PFSP 19214
Score = 93.2 bits (230), Expect = 2e-18
Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 1250 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301
+AG + + + G +W K +K +++ H ++E +EN S + I +
Sbjct: 9451 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9510
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+ H G Y++ +NK G + A + V+D P PP SDI S LSW DGG
Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9569
Query: 1362 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + +
Sbjct: 9570 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9629
Query: 1421 LTTVGEK--PEEPKDEVEV 1437
TT + P +P ++++
Sbjct: 9630 RTTARDPIYPPDPPIKLKI 9648
Score = 92.4 bits (228), Expect = 4e-18
Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
+ P F +L +K A FE R+ G P V W +G+P+ + R + G
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
SL + D G TC ATN G + L V E S ++ P K L
Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773
Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
+ ++ G + P V V EG+ RF C++TG PQP+V W
Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
++ S R V +G+ L+I D G N G +L IQ + RS
Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891
Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
+R + + E K+D ++K +R +
Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951
Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
SK + + T V K+ ++ + EE+K A
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
T PT +P +I + ++ PK + QSQ V + FR V
Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2056
Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
G P PE W+ G + R + + + L + DS + A N G+ S
Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2116
Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557
L V+ ++ +F+ L+D E P ++ W +G +
Sbjct: 2117 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2172
Query: 558 --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
R + V L I D Y+C V V ++ ++ ++
Sbjct: 2173 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2218
Query: 616 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672
A + F++ L D++V + + VS PE I W HN E++ + +
Sbjct: 2219 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2269
Query: 673 QRGTQHSLCIQEVFPEDTGTYT 694
R + +L +++V ED G Y+
Sbjct: 2270 SRRGRQNLTVKDVTKEDQGEYS 2291
Score = 92.4 bits (228), Expect = 4e-18
Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290
P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++
Sbjct: 18333 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18389
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ L + + G Y L + N G++ + + V+D+P PP G + + + L
Sbjct: 18390 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18449
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N
Sbjct: 18450 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18509
Query: 1410 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438
YG EP + +T KP P EVS
Sbjct: 18510 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18539
Score = 92.4 bits (228), Expect = 4e-18
Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
T + TV+ T + MP + I P AG VEL + G P +W
Sbjct: 23351 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23404
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
+++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP
Sbjct: 23405 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23464
Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394
G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L
Sbjct: 23465 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23524
Query: 1395 LPDHEYKFRVRAINVYG 1411
+EY FRV A N +G
Sbjct: 23525 TEGNEYVFRVAATNRFG 23541
Score = 92.0 bits (227), Expect = 5e-18
Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+P+T P + +N+ + EG + E + GYP P VTW+R I S F +
Sbjct: 892 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
G L+I ED G++TC A N +G + L V+ S + V++ T R
Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009
Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
F S V T S+ E P F TK + EG F C++ G P+P V W
Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069
Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
K VPL R VS +++ G L I DD G YT +V N G+ S SA L
Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 92.0 bits (227), Expect = 5e-18
Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
+AGE V++ G P T TW K K + +EN+++ S LTI + G Y
Sbjct: 20912 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 20971
Query: 1310 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I
Sbjct: 20972 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21030
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E
Sbjct: 21031 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 21090
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474
P P ++ + D + + + + ++++ + ER G G+
Sbjct: 21091 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21134
Score = 91.7 bits (226), Expect = 6e-18
Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y
Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16928
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y +
Sbjct: 16929 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 16988
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
+ D+ W + AT T+ V L EY+FR+ A N YG S
Sbjct: 16989 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17034
Score = 91.3 bits (225), Expect = 8e-18
Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)
Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301
KV+AGE V + VTG W K I++ +V SE ++L+I A
Sbjct: 9037 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9096
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS
Sbjct: 9097 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9155
Query: 1362 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418
+ Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ +
Sbjct: 9156 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9215
Query: 1419 SEL 1421
++
Sbjct: 9216 DKV 9218
Score = 91.3 bits (225), Expect = 8e-18
Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)
Query: 1226 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
P P PP++I +Q ++ G+++ L + G TW K +
Sbjct: 10832 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10891
Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
+ V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+
Sbjct: 10892 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 10948
Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401
IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y
Sbjct: 10949 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 11008
Query: 1402 FRVRAINVYG 1411
FRV A N YG
Sbjct: 11009 FRVAAENQYG 11018
Score = 91.3 bits (225), Expect = 8e-18
Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)
Query: 1232 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
PKA +PP+I + +KV RA ++ LF + G W R + +
Sbjct: 15477 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15534
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
+E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++
Sbjct: 15535 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15593
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
+S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV
Sbjct: 15594 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15653
Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431
A N YG P++ +E E+P P
Sbjct: 15654 LAENEYGIGLPAETAESVKASERPLPP 15680
Score = 90.5 bits (223), Expect = 1e-17
Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)
Query: 1249 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
V AG + + V+G P T TW M R QE+ +E + S + I ++ H G
Sbjct: 10164 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10220
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y
Sbjct: 10221 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10279
Query: 1367 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
IE +S + W + T + VQ L+ Y FR+ A N G + SE +
Sbjct: 10280 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10339
Query: 1426 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475
E PE P+D +EV EV TVT+ D Y +E RL G+ KF
Sbjct: 10340 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10391
Query: 1476 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524
K T + + KE + +S +N + K C
Sbjct: 10392 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10433
Score = 90.1 bits (222), Expect = 2e-17
Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
+RAG S+ LF + G W K +I+++ + V +S + L + + G Y
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16639
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y +
Sbjct: 16640 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16698
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E
Sbjct: 16699 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16758
Query: 1428 PEEP 1431
P+ P
Sbjct: 16759 PQPP 16762
Score = 90.1 bits (222), Expect = 2e-17
Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)
Query: 1228 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278
P P +++++P+ D++ + G V G + T PI C W K + I
Sbjct: 23746 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23805
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G
Sbjct: 23806 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23863
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397
DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L +
Sbjct: 23864 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23923
Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454
EY FRV A N +G S+P + E T PE P + EV D + + +
Sbjct: 23924 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 23983
Query: 1455 NTEQKVSDFY 1464
+ +V+ +Y
Sbjct: 23984 DGGSRVTGYY 23993
Score = 89.4 bits (220), Expect = 3e-17
Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)
Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679
AP F Q L + V++GS T +SG P PEV W +G I S +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122
Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
+ + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 800 VGECSCQVSLMLQ 812
VG + L++Q
Sbjct: 182 VGRATSTAELLVQ 194
Score = 89.0 bits (219), Expect = 4e-17
Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%)
Query: 408 QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467
Q++ P P+ V E +T +FRC V+G P+P+V W+L G +R+ + Y+
Sbjct: 1789 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1846
Query: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527
G HYL ++ ++ D+G TA N +G + L++++ F SVL+
Sbjct: 1847 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1900
Query: 528 GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+ V LQ V+ P + L + I + + E+ EL +
Sbjct: 1901 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 1958
Query: 576 EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618
+ G Y + E L + W E+K + E + +
Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2018
Query: 619 KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
KP AP + + V GS V+V G P PE W NG +I+ S+
Sbjct: 2019 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2078
Query: 670 H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728
+ + L I++V ED+ + +A N AGE + A L VQ T F + +
Sbjct: 2079 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2135
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758
V A ++ +PF V W +DG
Sbjct: 2136 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2165
Score = 87.8 bits (216), Expect = 9e-17
Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)
Query: 1232 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285
PK + P I + VRAG + LF V G TW K +++ +
Sbjct: 12225 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12281
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+
Sbjct: 12282 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12340
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
+S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV
Sbjct: 12341 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12400
Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431
A+N YG P+ + + EP
Sbjct: 12401 TAVNEYGPGVPTDVPKPVLASDPLSEP 12427
Score = 87.8 bits (216), Expect = 9e-17
Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)
Query: 1228 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
P P P I+ PE + +RAG ++ L+ V G P TW K +
Sbjct: 13303 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13362
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
++ + +++++ + L + G Y L +EN G ++ + + V+D P PP
Sbjct: 13363 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13421
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397
+I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L
Sbjct: 13422 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13481
Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428
Y FRV A N YG +P + + + P
Sbjct: 13482 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13512
Score = 87.8 bits (216), Expect = 9e-17
Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)
Query: 1237 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
PP+I + +KV RA ++ LF + G W K + ++ ++E + + +
Sbjct: 18732 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18789
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW
Sbjct: 18790 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18848
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG
Sbjct: 18849 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908
Query: 1413 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
P++ +E V E P P V +V T TI E+ SD
Sbjct: 18909 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 18950
Score = 87.0 bits (214), Expect = 2e-16
Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VRAG S + G TW R++ + ++ +++E N ++L+I + G Y
Sbjct: 17664 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17721
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I
Sbjct: 17722 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17780
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
+ +S K + +++ C TSF V++L Y FRV A N +G P + + E
Sbjct: 17781 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17840
Query: 1428 PEEP 1431
P P
Sbjct: 17841 PSPP 17844
Score = 87.0 bits (214), Expect = 2e-16
Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y
Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y +
Sbjct: 18011 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 18070
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
E D+ TW + AT T+ + L EY+FR+ A N YG S P
Sbjct: 18071 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 18118
Score = 85.5 bits (210), Expect = 4e-16
Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472
P F QS V E T F +SG P PEV+WF +G + +++ G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531
+ +SG YS A+N GQ T E L E A P+F L+ V +G
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
LQ V G P P + + +G IQ + + + E + L I +A PED GTY+ A N+
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616
+G+ + +A + V E+ ++K++ ++ A
Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211
Score = 85.5 bits (210), Expect = 4e-16
Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I D G++T A N +G ++V LTVE AVE
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
+ P F KL V +KEG + TG P P + WLK + + P ++ +
Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
G L+I D YT +N +G+ + +++++
Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602
Score = 84.0 bits (206), Expect = 1e-15
Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
+ G + +W K + + VE+S + L + ++ G YT+ ++N G+++
Sbjct: 13634 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
+++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W
Sbjct: 13694 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13753
Query: 1381 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
A+ + T+F V L EY FRV A N YG E
Sbjct: 13754 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13788
Score = 83.6 bits (205), Expect = 2e-15
Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 1237 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
PP+I FP VRAG ++++ ++G T + ++ + E +
Sbjct: 20101 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20160
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
+ + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W
Sbjct: 20161 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20220
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G
Sbjct: 20221 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20280
Query: 1413 SE 1414
S+
Sbjct: 20281 SD 20282
Score = 83.2 bits (204), Expect = 2e-15
Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)
Query: 1238 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
P I++F + +++GES+ + V G TW K +I++ +M++ + +
Sbjct: 21583 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21642
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W
Sbjct: 21643 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21702
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G
Sbjct: 21703 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21762
Query: 1413 SEP 1415
P
Sbjct: 21763 GRP 21765
Score = 82.8 bits (203), Expect = 3e-15
Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)
Query: 882 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938
H EE+ QQ + +++ ++S ++E + PA + + + VKP+ +
Sbjct: 676 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726
Query: 939 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997
SE K + + S + K T V P+ A+P F K +P
Sbjct: 727 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783
Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055
A + K LS + + + + A T+KP AE L A
Sbjct: 784 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840
Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095
+ KS + E+KK+V + GTT E+R E
Sbjct: 841 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894
Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + +
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
I +A ED G + C A N+AG SC V V + E T E + K +
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
+D ++ ++ A P A P I P QK+ G SV +V G W K
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071
Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325
+ KV N + G KL I + G YT++V NK G A +L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 82.4 bits (202), Expect = 4e-15
Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%)
Query: 405 MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457
++G++ + K + +P Q+V E V+ +VS + E W +G V+
Sbjct: 2294 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2352
Query: 458 EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517
+ + + D SH L + D+G YS T L S + +V +V + P
Sbjct: 2353 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2404
Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574
LKD VIEG VL+C V V + W LN + I+ ++ + L I
Sbjct: 2405 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2462
Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
D G Y + +G+V + ++V + K ++GL DL
Sbjct: 2463 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2498
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
+ V V++S + +V+W EI+ S + E G + L + + +D G YT
Sbjct: 2499 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2557
Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753
AGE T LTV ISKP T + Q + C +A +P
Sbjct: 2558 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2605
Query: 754 WLRDGKAL 761
WLRDGK L
Sbjct: 2606 WLRDGKHL 2613
Score = 82.4 bits (202), Expect = 4e-15
Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)
Query: 1086 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
D E R++ + AP K QD+ V GK L + + P A W + L T
Sbjct: 6615 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6674
Query: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
+++ S + +K D+G YK V +N G+AE + V D P
Sbjct: 6675 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6719
Query: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
PV E T + + ++ + G S ++ G V
Sbjct: 6720 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6756
Query: 1265 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322
+ I TW+ + + E + G + + + G + +N + +R
Sbjct: 6757 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6816
Query: 1323 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W
Sbjct: 6817 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6869
Query: 1383 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
T R+ S V D++ EY FRVRA N G +PS + V + E P V ++
Sbjct: 6870 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6929
Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493
D+ + V + + I ER GK + +LV + T KV K
Sbjct: 6930 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 6989
Query: 1494 FFKAYSAKEKENIRQEISIMNCL 1516
+ SA+ K + I+ L
Sbjct: 6990 YLYRVSAENKAGVSDPSEILGPL 7012
Score = 82.4 bits (202), Expect = 4e-15
Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG S + G W K ++ + V+ +++ + LTI A + G Y
Sbjct: 19826 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19883
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I
Sbjct: 19884 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 19942
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E +++ K W + C S+ V +L Y FRV N +G P++ E + EK
Sbjct: 19943 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 20002
Query: 1428 PEEPK 1432
P P+
Sbjct: 20003 PSPPE 20007
Score = 82.4 bits (202), Expect = 4e-15
Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G
Sbjct: 24535 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24594
Query: 662 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
EI + + ++ +G H L I V +D Y A N G V A L V+ P
Sbjct: 24595 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24654
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L
Sbjct: 24655 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24713
Query: 780 VLKK-VQPWHAGQYEILLKNRVG 801
V V+ AG Y + KNR G
Sbjct: 24714 VFPNGVERKDAGFYVVCAKNRFG 24736
Score = 82.0 bits (201), Expect = 5e-15
Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)
Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
R D+M L E P F LP N G +F + +PEP VTW+++GQ I G +
Sbjct: 25307 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25366
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ + +G + L I++V +D +YT A N G +LTV L P
Sbjct: 25367 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25419
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
TL P F L +EGQ F +++G P P + W K
Sbjct: 25420 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25460
Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
PL + + E L I +D G Y N +G S A L ++ L
Sbjct: 25461 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25520
Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
+ F + + V+K++ + L E+
Sbjct: 25521 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25552
Score = 81.6 bits (200), Expect = 6e-15
Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306
V+AG+++ L V G W K + + S +K++ + SK ++ A++ G
Sbjct: 11841 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11900
Query: 1307 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y
Sbjct: 11901 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 11959
Query: 1367 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423
+E ++ W AT + V L+ +EY FRVRA N GT P++ + T
Sbjct: 11960 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 12019
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464
+KP P D EV+ ++E V + + + ++ ++
Sbjct: 12020 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12059
Score = 81.6 bits (200), Expect = 6e-15
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)
Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L
Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24219
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
+ ED G YTC A N GEV T + L +Q P + K + A +G ++ +
Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24277
Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800
G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N
Sbjct: 24278 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24336
Query: 801 GECSCQVSLMLQN 813
G + + +Q+
Sbjct: 24337 GTVDAILDVEIQD 24349
Score = 81.3 bits (199), Expect = 8e-15
Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%)
Query: 416 FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
F + Q KE T+ F CE S P +V W+ +G V + ++ D H+L +
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2187
Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
L T D+ YSC + + + +L V F L+D V E L+
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2241
Query: 535 CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
C V + W N ++ T G L ++D ED G Y+ + +
Sbjct: 2242 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2296
Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
KK++ K + KP LQGLSD KV +G V + V+VS
Sbjct: 2297 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2338
Query: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707
E +W+ +G E+Q S+ H H L I+++ ED G Y+ +++G V
Sbjct: 2339 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2397
Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
+V I+ + V G ++ C ++ +V W + + + K
Sbjct: 2398 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2444
Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
+ + LV+ + G Y++++ RV E +C +S+
Sbjct: 2445 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2484
Score = 80.9 bits (198), Expect = 1e-14
Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+ E ++ F E+S P W L+G + R + E+ + G +L L K + +G
Sbjct: 5036 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 5093
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
A NA + L V E+ F+ LKD V E + +C + T
Sbjct: 5094 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 5142
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601
+ W I+ + + HI D+ +D G YT E + S +VT
Sbjct: 5143 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 5200
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
K F+ L D V +G T ++S + V+W N
Sbjct: 5201 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 5239
Query: 662 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
++ S G H L ++EV +D + E+ + A L V E P
Sbjct: 5240 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 5291
Query: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
+F K TA + + C ++ D V W +DG+ + + + + L +
Sbjct: 5292 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 5348
Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837
KK G+Y C C N + A L + +P ++ G
Sbjct: 5349 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 5399
Query: 838 ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889
+ D +G W +GQ D E + K + T + + +A
Sbjct: 5400 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 5455
Query: 890 QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949
+ L ++L + LS D+K ++ F + R+ PKT R + Q
Sbjct: 5456 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 5505
Query: 950 QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007
++ D R L K GT + V + A F + + +G E + K
Sbjct: 5506 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 5559
Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067
+ K ++ + + V + +K N + T + + + + + S + ++L
Sbjct: 5560 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 5618
Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
D + + + G + K + +G P F KLQD E +++LQC++S A
Sbjct: 5619 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 5674
Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ W +GK +K +K ++ +G + ++KAL D G Y C D G + S ++ +
Sbjct: 5675 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5730
Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
+D E+K RP S+ V+ TE+
Sbjct: 5731 EDR---------EIKLVRPLHSV-EVMETET 5751
Score = 80.9 bits (198), Expect = 1e-14
Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PPKA + ++ + +RAG + L V G W K K++ E + ++ +
Sbjct: 22671 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22728
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ I + G YTL V+N G++ V + V+D P P G S + TL
Sbjct: 22729 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22787
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N
Sbjct: 22788 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22847
Query: 1410 YG-----TSEPSQESELTTVGEKPEEPKD 1433
YG SEP T+ P P++
Sbjct: 22848 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22876
Score = 79.7 bits (195), Expect = 2e-14
Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
+AG+++++ V G T TW K + +++++ + E + + L I + G Y
Sbjct: 14706 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14765
Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
L N +G + + V D P PP G ++ S +T SW DGG + +Y +E
Sbjct: 14766 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14825
Query: 1370 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411
+ + + TW ELA T T++ L EY+FRV+A N YG
Sbjct: 14826 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14868
Score = 79.3 bits (194), Expect = 3e-14
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 1738 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1797
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284
Query: 1798 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 79.3 bits (194), Expect = 3e-14
Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%)
Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R
Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079
Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
LVI V ED +A N +G L V+ AKQL
Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127
Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199
F +L VV KE M F C+ T P +V W K +
Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
+ + + + L I ++ D Y+C++V +A+L ++G A
Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2222
Query: 260 FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
FV+E + E+ ++S E+ + +E + K + +RG +
Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282
Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363
+ E K +CK + P +LQ S + VQ E + GV
Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341
Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420
G+E +P+ + L +D+ + A IP G S S
Sbjct: 2342 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400
Query: 421 QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
+K+ ++ C+VS V W+L + + + ++ L +
Sbjct: 2401 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2459
Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
+ D G Y G++ + L VE++ ++ L+D E Q+ V +
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2508
Query: 536 SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
+ + + + W + I+ + + + +L + + + +D G YT A G+
Sbjct: 2509 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2563
Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
S +TV A SKP L+D V + + +V+ NP
Sbjct: 2564 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2602
Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+ WL +G + + + E G + L I +D G YT + S +T A L V
Sbjct: 2603 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2658
Query: 713 QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
+ I K +++T + Q + + + V W+++G L
Sbjct: 2659 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701
Score = 79.0 bits (193), Expect = 4e-14
Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471
P+F ++ + V+F ++ P+P V W+ G ++ + + D G +
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25377
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528
L + T D Y+ A N G+ SC L V + P F +L + EG
Sbjct: 25378 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 25437
Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584
Q + V G P P + W +GQP+ + G+ LHI+D LPED G Y
Sbjct: 25438 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 25497
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEY 611
A N G SC A + V E+ +K E+
Sbjct: 25498 ATNTAGSTSCQAHLQV-ERLRYKKQEF 25523
Score = 78.6 bits (192), Expect = 5e-14
Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)
Query: 1225 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276
+P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K
Sbjct: 8292 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8349
Query: 1277 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310
++QE E + ++NS+ G S+L + + + G Y +
Sbjct: 8350 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8409
Query: 1311 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370
VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E
Sbjct: 8410 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8468
Query: 1371 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
D + W + +T R ++V L+ EY FRVRA N +G P L V +
Sbjct: 8469 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8526
Query: 1428 PEEPKD 1433
P P D
Sbjct: 8527 PFGPPD 8532
Score = 78.2 bits (191), Expect = 7e-14
Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%)
Query: 36 ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94
I P +++ + EG A E +V V W+ N + I R + ++GT LVI+
Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2459
Query: 95 AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154
H D G Y G + L+VE
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2487
Query: 155 IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214
K L + E Q F +++ V W + ++PS++ +
Sbjct: 2488 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2539
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272
+ L + + +DD G YT +G+ S +L++ G + ++ +T A + +
Sbjct: 2540 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2594
Query: 273 KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329
EV N SK L + + N S G A K+ + K S
Sbjct: 2595 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2654
Query: 330 RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378
+ + ++KT ++T+ + P G+ GV+ S E+
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2714
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
+ + + + V R + + K KP+ EN TV F VS
Sbjct: 2715 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2773
Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
P V WF + ++ + + + H L L D+G Y+ GQL C
Sbjct: 2774 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2827
Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
L VE L + + +K+ V E + +C V VP + WL NG I+ +
Sbjct: 2828 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2879
Query: 559 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
+ + +L I + ED YT + N QVS + VT
Sbjct: 2880 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2921
Query: 616 APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674
PI + L D+ + +T V V+ WL NG EI+ ++ +
Sbjct: 2922 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 2973
Query: 675 GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
HSL I+ V D YT AG+ + A L V+ H F + +
Sbjct: 2974 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3025
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
+ + C ++ +P TV W++D + L + T ++ + + V L++ + AG+Y +
Sbjct: 3026 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083
Query: 795 LLKNRV 800
+ V
Sbjct: 3084 VAGGNV 3089
Score = 78.2 bits (191), Expect = 7e-14
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)
Query: 1228 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
P T A + P + F + +V + + TG T TW K ++ + +K
Sbjct: 7011 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7070
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI
Sbjct: 7071 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7129
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404
S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V
Sbjct: 7130 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7189
Query: 1405 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433
A N G EP+ E ++T P+ P++
Sbjct: 7190 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7221
Score = 78.2 bits (191), Expect = 7e-14
Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
PA ++L V ++ +L + D + I L K + F + + + ++
Sbjct: 22174 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22233
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
E+ + + ++ AKNDAG +E P+ + V+
Sbjct: 22234 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22265
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+K+ T + Q+I +AG + ++G TW +
Sbjct: 22266 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22315
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G
Sbjct: 22316 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22375
Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396
S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L
Sbjct: 22376 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22435
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
EY FRV + N +G S+P + + + + E P P
Sbjct: 22436 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22468
Score = 77.4 bits (189), Expect = 1e-13
Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%)
Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
S+DVV + G + A P F +KP Q++ E +V F C+V G PKP V W
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072
Query: 451 GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509
G P+ + + G L + D+G Y+ N G+ S S +L +E
Sbjct: 1073 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567
+ S +L V FV + V G P + + + ++ +A+
Sbjct: 1132 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625
+ ++ + + + E + ++ T E+ + + + + ++ S+ F
Sbjct: 1188 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1247
Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683
+ + ++++G VT ++SG P P++ W +G I+ E + F Q G + SL I
Sbjct: 1248 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1306
Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732
V PED G YT A N G L V+ P +I PRSV+
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366
Query: 733 S 733
S
Sbjct: 1367 S 1367
Score = 77.0 bits (188), Expect = 2e-13
Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI
Sbjct: 16858 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16917
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++ +D G Y N GQ S ++ D P + K P
Sbjct: 16918 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 16960
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
D + + PP QI + ++ T W
Sbjct: 16961 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 17004
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332
+ + +KV + G++ + + EN+ G A + +V +P
Sbjct: 17005 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 17052
Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385
PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT
Sbjct: 17053 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 17106
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
T F Q+L EY+FRV A N+ G + S+ SE + + P
Sbjct: 17107 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17152
Score = 76.6 bits (187), Expect = 2e-13
Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+
Sbjct: 6453 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6511
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206
+D Y C ++ +A + + V+ +AP ++ E+ +
Sbjct: 6512 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6571
Query: 1207 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241
++++ V G + + K + + A P+I
Sbjct: 6572 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6631
Query: 1242 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301
+D V G+ + + W K + + ++ + + IL A+
Sbjct: 6632 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6688
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+ G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS
Sbjct: 6689 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6747
Query: 1362 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418
+ Y +E D KTW LAT R+ S F V L EY FRV A N GT EP +
Sbjct: 6748 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6806
Query: 1419 SELTTVGEKPEEPKDEVEVSDDD 1441
K + P + V+ D
Sbjct: 6807 DNPVEARSKYDVPGPPLNVTITD 6829
Score = 76.3 bits (186), Expect = 3e-13
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 1721 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1779
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918
Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977
Query: 1840 ATCTAELIVETMEEGEGE 1857
+ + L V+ EE E E
Sbjct: 978 VSTSCYLAVQVSEEFEKE 995
Score = 75.9 bits (185), Expect = 3e-13
Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%)
Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678
K P+ L D +G V +T ++ EV W + E F Q +
Sbjct: 4364 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4421
Query: 679 SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737
+L I +V ED G Y CEA N +G+ T A LTV + P K + +LG
Sbjct: 4422 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4478
Query: 738 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797
+C I P W + G+ + ++ + ++ + +L + + Q G+Y
Sbjct: 4479 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4537
Query: 798 NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
N G SC +L + R L R+P E++ S+
Sbjct: 4538 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4584
Query: 854 PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 913
P + +E + E V K+ + + + EV + R+ +K+ T +
Sbjct: 4585 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4637
Query: 914 DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 970
IP + + + +V KP V E + +P V V+ KK +K P E
Sbjct: 4638 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4694
Query: 971 VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 1027
P P + G KK P+ + + E P + + PLK V
Sbjct: 4695 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4747
Query: 1028 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1073
K + +G++ E L A K N++ + K D K+
Sbjct: 4748 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4807
Query: 1074 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1124
+ C + G+ T K + K ++V V +G+ L L C+++ +
Sbjct: 4808 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4867
Query: 1125 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1183
++W +GK ++ I+ G + +++I A D G Y +N A ECS
Sbjct: 4868 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4924
Query: 1184 QVTV 1187
V V
Sbjct: 4925 CVKV 4928
Score = 75.9 bits (185), Expect = 3e-13
Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)
Query: 1052 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105
N++P ++LK +E + D + + + +A G ++ + SE+ P +
Sbjct: 7963 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 8022
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D
Sbjct: 8023 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8082
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
G+Y +N G A S V V P ++K+ SD T
Sbjct: 8083 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 8124
Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
PP+ G PI ++ R++ ++
Sbjct: 8125 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8156
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343
V + EN T+ + + NK+G + N + P P P ++
Sbjct: 8157 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8216
Query: 1344 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395
+ ++T++W YDGGS + Y IE + WK C ++ + L
Sbjct: 8217 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8273
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442
EY+FRVRA N G SEPS+ + T + + PK +EV DE
Sbjct: 8274 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8324
Score = 73.9 bits (180), Expect = 1e-12
Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
VKE Q V F CEV+ + WF + I + +D + L + A D
Sbjct: 6279 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 6336
Query: 485 YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
Y+ + +N +G+ + + L VE + V P LKD +E + C V V
Sbjct: 6337 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 6391
Query: 544 RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
+ W NG+ + + H I+D D G Y VT
Sbjct: 6392 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 6435
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
+ KS +E L+ AP++ F++ L D V + + Q+S V W NG
Sbjct: 6436 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 6487
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719
EI+E + + FE+ G+ H L I++ +D Y C + +++A L V+E P +
Sbjct: 6488 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 6543
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
+P P+ + + G V+ + D V WLR+ + + H +++ + L
Sbjct: 6544 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 6596
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVS 808
+ ++P G+Y + K++ +++
Sbjct: 6597 QICDIKPRDQGEYRFIAKDKEARAKLELA 6625
Score = 73.9 bits (180), Expect = 1e-12
Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V+V G L + +S P + + +G LK T ++++++++ D G
Sbjct: 20114 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20173
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224
Y+ A N +G + + V D P P V+ TE T+K
Sbjct: 20174 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20219
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+P PK + + I+ ++ S ++ +V+ T + T MK K E+
Sbjct: 20220 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20269
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344
+EN + + + S V L P PP+ TP +++
Sbjct: 20270 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20310
Query: 1345 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402
S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F
Sbjct: 20311 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20370
Query: 1403 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
RV A N G +PS SE + E P++ V ++D + + ++ + K++
Sbjct: 20371 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20429
Query: 1463 FYDIEER 1469
Y +E R
Sbjct: 20430 -YIVERR 20435
Score = 73.6 bits (179), Expect = 2e-12
Identities = 33/91 (36%), Positives = 56/91 (61%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLV 3790
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328
R+++ ++ +++ G+ L + ++ + + EN+ G S + T +
Sbjct: 23895 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 23954
Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386
+ P+PP+ P D+ SS++LSW DGGS V Y IE +++ W +
Sbjct: 23955 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 24014
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437
T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+
Sbjct: 24015 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 24067
Score = 72.4 bits (176), Expect = 4e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)
Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++
Sbjct: 8726 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8781
Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347
N S+L I A ++ G Y + N GS+ A + V D P P R
Sbjct: 8782 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8841
Query: 1348 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407
L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A
Sbjct: 8842 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8900
Query: 1408 NVYGTSEPSQESELTTV 1424
N +G P + + V
Sbjct: 8901 NKFGCGPPVEIGPILAV 8917
Score = 71.6 bits (174), Expect = 7e-12
Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 16/152 (10%)
Query: 1700 AVRAIGRLSSMAMIS--GLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK 1757
A A+G++SS A +S G S + +T + ++ +E + Q K
Sbjct: 3372 ASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQ-------------K 3418
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCSL 1816
P F + + L V G RF ++ G P PE+ WF + Q I ++ ++E G +
Sbjct: 3419 PSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALM 3478
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+I D + +Y+CKA NS GEATC A L V
Sbjct: 3479 LIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510
Score = 71.6 bits (174), Expect = 7e-12
Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
+D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T
Sbjct: 20792 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20850
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+
Sbjct: 20851 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20904
Score = 71.2 bits (173), Expect = 9e-12
Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324
P T W++ K + +V+ N K + +L EN G + +
Sbjct: 7552 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7600
Query: 1325 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
+ + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W
Sbjct: 7601 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7660
Query: 1381 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437
+A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV
Sbjct: 7661 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7720
Score = 70.9 bits (172), Expect = 1e-11
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P
Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538
Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P + W +N I + ++ G +G +L I + +D YT A N +G
Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597
Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
++ VE FA+ + + G +AP +E +G + P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657
Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
F KL + +K F C++T G P V WL PL+ + R+ + + G L+
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
D G+ TC N G SA L ++ +S V E++
Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759
Score = 70.9 bits (172), Expect = 1e-11
Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%)
Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
SE +GT P F +++ + ++ G L V P I W NG L + +G
Sbjct: 3575 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3634
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
S+ I ED G Y C+A ND G+ CS + + N+K K
Sbjct: 3635 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3680
Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
TE+++ V K P PP ++ + + G V G T T
Sbjct: 3681 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3732
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329
W K KQ+ S + + ++ NGS I+ ++E G Y EN LG L V+
Sbjct: 3733 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3792
Query: 1330 KPDPPAGTPC 1339
+ TPC
Sbjct: 3793 EDTDMTDTPC 3802
Score = 70.9 bits (172), Expect = 1e-11
Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G
Sbjct: 21201 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21260
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y + N C++ V P + T P K + P
Sbjct: 21261 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21291
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283
I+F E + +SV L V G ITC ++ R+ Q +
Sbjct: 21292 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21333
Query: 1284 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337
M + + K+ L E+ + + EN+ G Q V+ +V K P PP G
Sbjct: 21334 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21390
Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395
P ++ S ++L+W YDGGS V + +E + + W+++ T + L+
Sbjct: 21391 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21450
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455
+Y+FRV A N G S PS S+ T+ P +P + D V T+T+
Sbjct: 21451 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21502
Query: 1456 TEQKVSD------FYDIEERLGSGKF 1475
+ D Y IE+R G+ ++
Sbjct: 21503 WNPPLRDGGSKIVGYSIEKRQGNERW 21528
Score = 70.5 bits (171), Expect = 1e-11
Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A + I+ L+V +D F +P +++ + E A+FE + E
Sbjct: 5092 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5140
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W + I S +F + + LVI+ +D G YT E
Sbjct: 5141 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5185
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
VEG K R + KF + L VKEG+ F
Sbjct: 5186 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5222
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C+++ + V W K + L S V +S + LE+ V DD+ V +
Sbjct: 5223 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 5277
Query: 242 ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283
S +A+L + D + + A D V K+V K+
Sbjct: 5278 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 5337
Query: 284 KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337
K D L K K +G G+ AN + R K+E P + V
Sbjct: 5338 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 5392
Query: 338 LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397
+ I L V + + G + + E Q G+ + +V +
Sbjct: 5393 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 5451
Query: 398 AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456
AAN + + P P S +V E KF CEVS PK W L+GT
Sbjct: 5452 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 5508
Query: 457 QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516
+ E+ +D H + + A D Y A + +L + + F
Sbjct: 5509 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 5559
Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576
+ LKD E + V + + R+ W N Q + RS + +QD
Sbjct: 5560 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 5610
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
T+ L+ + Q+ A SE L V P F L D ++
Sbjct: 5611 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 5659
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
+V + ++S P V W +G EI+ S++ + G + L +++ D G YTC+
Sbjct: 5660 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 5718
Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
G +T L +++ + + SV ++ I+ D +W
Sbjct: 5719 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 5769
Query: 757 DGKALCKDTGHFEVLQNEDVFTLVL 781
G+AL + T E+ + + +LVL
Sbjct: 5770 KGEALLQ-TPDCEIKEEGKIHSLVL 5793
Score = 70.5 bits (171), Expect = 1e-11
Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L + V G K+ L V+ P I WT LK K I + +V+I +
Sbjct: 7325 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7384
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y A N G+A +V V D P PP +D T +
Sbjct: 7385 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7426
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
PP+ +I + +++ E W K ++++
Sbjct: 7427 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7470
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339
K T L +E+ + + EN G Q + +T + DPP G P
Sbjct: 7471 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7517
Query: 1340 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396
SDI ++TL+W DGGS + Y +E D W + T++ V+ L
Sbjct: 7518 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7577
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
+Y+FRV A N+ G +PS+ +E + + + P
Sbjct: 7578 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7612
Score = 70.1 bits (170), Expect = 2e-11
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1815
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 70.1 bits (170), Expect = 2e-11
Identities = 59/236 (25%), Positives = 92/236 (38%), Gaps = 24/236 (10%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
PA LQD +EG+ QC+VS + W K +K ++F ++Q + I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDD-APASENTKAPEMKSRRPKSSLPPVLGT 1216
+A PED G Y VA N GQ + ++++ + ENT +
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWH-------------V 3404
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
+ KK+P P IQ +V GE+V +V+G W ++
Sbjct: 3405 SLSVSFKKEP-------LGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQ 3457
Query: 1277 QIQESEHM--KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
I ++ + E S + + I+ A EH G Y+ N G LTV K
Sbjct: 3458 LILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPK 3513
Score = 69.3 bits (168), Expect = 3e-11
Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)
Query: 1217 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
ESD V + P P TP A+ + + V G S + + + + W
Sbjct: 17038 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 17097
Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
K K I K +N E G + + + EN +G +A N
Sbjct: 17098 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17146
Query: 1332 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387
DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T
Sbjct: 17147 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17206
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438
F V L D Y+FRV A N G S+PS + T ++ E P +D + V+
Sbjct: 17207 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17266
Query: 1439 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495
+ E D + T + + +IEE F+ L+ K ++ G++
Sbjct: 17267 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17326
Query: 1496 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554
+A + ++ + +++ P+ VQ EK ++ + GG + E
Sbjct: 17327 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17386
Query: 1555 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598
E + E + +++ EG EY+ + IM VNK G
Sbjct: 17387 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17428
Score = 69.3 bits (168), Expect = 3e-11
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Query: 1306 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357
GC Y + EN G ++ DP P P D +++T++W +
Sbjct: 19678 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19737
Query: 1358 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS
Sbjct: 19738 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19797
Query: 1417 QESELTTVGEKPEEPKDEVE 1436
S+ E+ EEP +++
Sbjct: 19798 DSSDPQIAKEREEEPLFDID 19817
Score = 69.3 bits (168), Expect = 3e-11
Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%)
Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
E S ++EVT + E + + + A + + S+ + R SP +
Sbjct: 25857 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25916
Query: 311 --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368
S+PQP E + ++ + SP TP + PR+P SP
Sbjct: 25917 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 25951
Query: 369 EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423
ER R A F +R + + K + R+ + Q+ P+ + +S
Sbjct: 25952 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 26011
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
V Q +F V P EV W+ G ++ + I +G L +L T DSG
Sbjct: 26012 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 26070
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542
TY +N +G+ S TL V G D+ S R V
Sbjct: 26071 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 26108
Query: 543 PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
PR + + YA S+ EA + ++ + E + + +A ++ +A
Sbjct: 26109 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 26168
Query: 597 WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
++ EK ++RK + L A L + V +G + G P P V
Sbjct: 26169 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26220
Query: 655 IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714
WL G + S + + I V D G Y+ NS G+ + LT+Q+
Sbjct: 26221 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 26280
Score = 69.3 bits (168), Expect = 3e-11
Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L AP L R+ + G +F V+ P +V W+ NG + + G
Sbjct: 25998 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 26056
Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
+L I H +D G Y T + T G R V EL
Sbjct: 26057 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 26116
Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
T ++A K+ + S ++ + + ETR S+
Sbjct: 26117 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26175
Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
+ TK + V EG+ RFSC G P P VTWL+ L SAR
Sbjct: 26176 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26235
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
V+ EI V D G Y+ +V N GK L+IQ ++ V E KA
Sbjct: 26236 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26288
Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
S R V S E ++ S EA K SP+ P P + + E +
Sbjct: 26289 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26339
Query: 328 SPRTAP 333
P +AP
Sbjct: 26340 LPVSAP 26345
Score = 68.9 bits (167), Expect = 4e-11
Identities = 55/191 (28%), Positives = 77/191 (40%), Gaps = 11/191 (5%)
Query: 444 EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTASNAQGQLSCSWTL 502
EV W+ E V E + +D ++ L + K T D G Y C A N G+ + S L
Sbjct: 4396 EVNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4454
Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE 562
V V AP ++ V G C ++ P R W G+ I Y C
Sbjct: 4455 TV----VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCS 4509
Query: 563 AG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
++ L I D G YTC A N G VSC+A +TV +K LLP
Sbjct: 4510 IRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKP 4569
Query: 619 KPTAPIFLQGL 629
+P + L+ +
Sbjct: 4570 EPKEEVVLKSV 4580
Score = 68.9 bits (167), Expect = 4e-11
Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)
Query: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
P KL V V G + L+ V P + WT + T+ + +
Sbjct: 11829 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11888
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213
S+ KA D G Y A N AG V V D P N K ++ S R
Sbjct: 11889 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 11940
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
TV P P+ + I++ E +++ W
Sbjct: 11941 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 11973
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330
+ + G+ +T L E+ + + ENK+G+ + V+ K
Sbjct: 11974 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 12021
Query: 1331 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
PDPP T + + +T+ W YDGG ++ Y +E + + W + +
Sbjct: 12022 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 12077
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
VQ+LLPDHEY+FRV+A N G EPS S V + P EP
Sbjct: 12078 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 12124
Score = 68.6 bits (166), Expect = 6e-11
Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI
Sbjct: 19023 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 19082
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++A ED G Y+ N AG + V D P PP
Sbjct: 19083 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 19124
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+ + PP+ QI + ++K + + TW +
Sbjct: 19125 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19168
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333
+ + +K+ GS+ + + EN+ G + VV + P
Sbjct: 19169 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19216
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386
P GTP S++ ++W DGGS V Y +E +W ANK
Sbjct: 19217 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19271
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446
T V L Y++RV A N+ G + S+ E P +P + EV++ K
Sbjct: 19272 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19330
Query: 1447 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475
+ + + K++ + L G++
Sbjct: 19331 LKWSKPHYDGGAKITGYIVERRELPDGRW 19359
Score = 68.6 bits (166), Expect = 6e-11
Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)
Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+
Sbjct: 26755 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26814
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194
++ S+ I A D G Y AKN GQ + + V + P+ E
Sbjct: 26815 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26874
Query: 1195 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235
++++ +M + + ++S + + + + K A + +
Sbjct: 26875 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26934
Query: 1236 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
+PP+I P D + G+ + + TG TW
Sbjct: 26935 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26994
Query: 1276 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ +
Sbjct: 26995 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048
Score = 67.4 bits (163), Expect = 1e-10
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 1737 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 67.4 bits (163), Expect = 1e-10
Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154
P Q+LQ V V GK +S P I W + L T KF+ QE +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
+ +A PED +Y C AKND G A S ++V+ PE+ S P +P
Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
PP II +D G+ +V+GT + +W
Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
K+I+ S ++ E+ +L I A E G YT + N +G + NL++
Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Score = 67.0 bits (162), Expect = 2e-10
Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
++ + V G + + P T WT +G +KT + + + ++I+ L
Sbjct: 11145 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11204
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y+ N AG + +TV D P P + + T T+
Sbjct: 11205 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11252
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
+P P P I E Q R + +G V+
Sbjct: 11253 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11283
Query: 1284 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336
+GS T L GC + + ENK+G + V K P P G
Sbjct: 11284 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11336
Query: 1337 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390
P +DI ++ T+SW DGGS + Y +E W NKT F
Sbjct: 11337 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11391
Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
V L + Y+FRV A N+ G S+PS S+
Sbjct: 11392 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11421
Score = 67.0 bits (162), Expect = 2e-10
Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12994
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224
A+N +G + ++ V D P + K +M S R S P L G+E +
Sbjct: 12995 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 13054
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
K P A +V+ T PIT ++ K I+ E+
Sbjct: 13055 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 13087
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340
+ + ENK G + K DPP P
Sbjct: 13088 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 13124
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
S+I +T+SW + DGGS + Y +E ++ W ++ + L
Sbjct: 13125 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13184
Query: 1399 EYKFRVRAINVYGTSEPSQESE 1420
EY+FRV AIN G +PS S+
Sbjct: 13185 EYEFRVTAINKAGPGKPSDASK 13206
Score = 66.6 bits (161), Expect = 2e-10
Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)
Query: 1083 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134
G +D S+ Q ++ L D+ K L+++ S P ++W+
Sbjct: 19792 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19851
Query: 1135 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
L+T ++ + S S++IE A D G Y +N A + V V D P
Sbjct: 19852 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19907
Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254
PP T D T + A + + PE+
Sbjct: 19908 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19932
Query: 1255 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312
G P+ ++ R + S+ V + N ++L+ + Y V
Sbjct: 19933 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 19981
Query: 1313 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E
Sbjct: 19982 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 20040
Query: 1370 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429
+ K W + A +ST V L + EY FRV A N G S+P + + E+ E
Sbjct: 20041 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 20100
Query: 1430 EPKDEVE 1436
P+ +++
Sbjct: 20101 PPEIDMK 20107
Score = 65.9 bits (159), Expect = 4e-10
Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8800
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y A N G + +V V D P P L PV+ T +
Sbjct: 8801 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8846
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
P+ + + II+ +D K+ T QPI E+E K
Sbjct: 8847 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8882
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342
+ +T L QE+ + ++ +NK G ++ + VD PP ++
Sbjct: 8883 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 8933
Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400
S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y
Sbjct: 8934 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 8993
Query: 1401 KFRVRAINVYGTSEPS 1416
+FRV+A+N G SEPS
Sbjct: 8994 EFRVKAVNEIGESEPS 9009
Score = 65.9 bits (159), Expect = 4e-10
Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15163
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A N G A+ V V D P P V S+ V P
Sbjct: 15164 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15210
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
A + I+Q E ++ W ++Q ++
Sbjct: 15211 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15241
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346
K+T L E+ + ++ NK G + + V+ PDPP P + I
Sbjct: 15242 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15297
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+
Sbjct: 15298 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15357
Query: 1405 RAINVYGTSEPSQES 1419
A N G S PS S
Sbjct: 15358 MAENAAGISAPSPTS 15372
Score = 65.9 bits (159), Expect = 4e-10
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW +
Sbjct: 15644 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15702
Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q
Sbjct: 15703 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15762
Query: 1418 ES 1419
S
Sbjct: 15763 LS 15764
Score = 65.9 bits (159), Expect = 4e-10
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T
Sbjct: 22970 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 23028
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K
Sbjct: 23029 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 23082
Score = 65.5 bits (158), Expect = 5e-10
Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
+AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G
Sbjct: 24554 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24613
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
L+I +V ++D Y ATN G+ T L VE L
Sbjct: 24614 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24655
Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
PK +G V G++ +G+P P +TW KG + + V
Sbjct: 24656 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24704
Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
L +GV + D G Y N G + EL + + R
Sbjct: 24705 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24758
Query: 269 SDVRKEVTNVISKESKLD 286
SDV ++ N+ E D
Sbjct: 24759 SDVSRDSVNLTWTEPASD 24776
Score = 64.7 bits (156), Expect = 8e-10
Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+ K + G+ L ++ V P I W +G+ LK T + + + + + I
Sbjct: 17940 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17999
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++ +D G Y A N AG A + V V + P PPV
Sbjct: 18000 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 18041
Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
D + PP QI + +++ T TW
Sbjct: 18042 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 18085
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331
+ + +K+ + G++ + + EN+ G + V+ +P
Sbjct: 18086 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18133
Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389
PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F
Sbjct: 18134 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18192
Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
L EY+F+V A N+ G +PS+ SE + + P
Sbjct: 18193 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18234
Score = 64.7 bits (156), Expect = 8e-10
Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)
Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R
Sbjct: 26166 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26224
Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
GQ +++ R + + TF I +V D G Y+ N G ++ LT++ +
Sbjct: 26225 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26282
Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
K + P K+ R +P ET+P+ +
Sbjct: 26283 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26342
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
PPK L KE + + +C + +VTW K L+ + +G
Sbjct: 26343 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26400
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
L+I+ + + D G Y C + G + + + Q S + + ++ SD +
Sbjct: 26401 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26460
Query: 275 VTNVISK 281
+ V K
Sbjct: 26461 ESTVTRK 26467
Score = 64.3 bits (155), Expect = 1e-09
Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VR G+++ + +V G TW K K + + + + +L I A + G Y
Sbjct: 11548 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11607
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ +N G Q + V+D+P P +++ + T+SW +GGS + ++ +
Sbjct: 11608 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11666
Query: 1369 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425
E K W +A+ + +LL ++EY FRV A N G P+ E++ +
Sbjct: 11667 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11725
Query: 1426 -EKPEEPKD 1433
++P EP++
Sbjct: 11726 IDRPGEPEN 11734
Score = 64.3 bits (155), Expect = 1e-09
Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)
Query: 1215 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269
G +S+ V + P P PP PP I+ D SV L K TG PIT
Sbjct: 13789 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13837
Query: 1270 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
++F R + K K+T L E+ + ++ N G + +
Sbjct: 13838 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13895
Query: 1328 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
V DP P G P +I +S+TL W YDGG + Y +E D +K+W +
Sbjct: 13896 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 13955
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431
+F V DL+ +Y+FR+RA N G S PS+ +E ++ E P
Sbjct: 13956 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14004
Score = 63.9 bits (154), Expect = 1e-09
Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
QE C Y + EN+ G Q + V + P PP G D+ +S++LSW +
Sbjct: 16726 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16784
Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P
Sbjct: 16785 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16842
Score = 63.5 bits (153), Expect = 2e-09
Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271
S+ TV + P K P P + + +V+ E + G +V G + + W
Sbjct: 15957 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 16015
Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+K K K E G + + + G +G V P
Sbjct: 16016 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 16066
Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389
P G P A + +S+TL W +YDGGS + Y +E + W + + T F
Sbjct: 16067 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16126
Query: 1390 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432
V L+ DH Y+FRV A N G SEPS+ + T ++ + P+
Sbjct: 16127 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16170
Score = 63.5 bits (153), Expect = 2e-09
Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+
Sbjct: 20515 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20574
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
+N G A + +V + D P P + T T+ +P P
Sbjct: 20575 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20621
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
A + I++ E +V W SEH++ E
Sbjct: 20622 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20651
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
T + E+ + + NK G + + +VV K P PP G P + I +
Sbjct: 20652 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20708
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404
S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV
Sbjct: 20709 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20768
Query: 1405 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439
A+N G S+ SE + P P ++ ++D
Sbjct: 20769 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20805
Score = 63.2 bits (152), Expect = 2e-09
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383
P P P D SS++L W + DGGS ++ Y +E+ + WK + T
Sbjct: 9332 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9391
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D
Sbjct: 9392 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9446
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383
+ KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ +
Sbjct: 10738 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10796
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432
C T + V L YKFRV A+N G S+P+ E V ++ E P+
Sbjct: 10797 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10845
Score = 63.2 bits (152), Expect = 2e-09
Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)
Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063
K V +S PLS P L+ K + TL L P+ G AK D + S
Sbjct: 12416 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12466
Query: 1064 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104
+EE D + + + + G + +K E++G A +Q L
Sbjct: 12467 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12526
Query: 1105 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
+ + + GKKL ++ V P T W + T+ + + + S + I
Sbjct: 12527 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12586
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215
+ +D G Y A+N +G +V V DAP PP +
Sbjct: 12587 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12631
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
++DA P + + I+ E V G+ V VT T +
Sbjct: 12632 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12682
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
K I E++ +EN G L K+ AQ V +P
Sbjct: 12683 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12727
Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388
T D + ++W DGGS + Y IE +W AN T RST
Sbjct: 12728 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12778
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
+ L+ EY FR+ A+N G+S PS+ +E T P +P + EV D
Sbjct: 12779 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12828
Score = 63.2 bits (152), Expect = 2e-09
Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)
Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G
Sbjct: 25208 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25266
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C+ N G EL V+G +++ +T+ + +T + E PP+F
Sbjct: 25267 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25320
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
L G+ RF IT P+P VTW K ++P + + G+ L I
Sbjct: 25321 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25380
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ V DD YT + N G+ S A+L++
Sbjct: 25381 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 62.8 bits (151), Expect = 3e-09
Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)
Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143
D EK+ + P FK+KL + + +C+++ DP + W +GK L+
Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704
Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203
+ + E CS+ A D G+ C A N G S + V D E + E +
Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760
Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263
+ L + E A T K P I+ +PE +V GE+ +VTG
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323
W + I++S+ +V + L I+ + G + EN G + +V
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879
Query: 1324 NLTVVDKPD 1332
L + + D
Sbjct: 1880 KLEIQQRED 1888
Score = 62.8 bits (151), Expect = 3e-09
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386
KP PP P DI SS+ LSW YDGG +Q Y +E D + W
Sbjct: 16465 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16523
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
T+ V+ LL HEY FR+ AIN G E + V EK E P ++++
Sbjct: 16524 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16574
Score = 62.4 bits (150), Expect = 4e-09
Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G
Sbjct: 14414 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14471
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
+ + N +GK S ++++ LD+ +R T T V +TN
Sbjct: 14472 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14529
Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
I ++ ++ A K C+ G S A N +P ++
Sbjct: 14530 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14589
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
++P ++ T S+++L P+P+ G ++ E +R + T T
Sbjct: 14590 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 14644
Query: 386 QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425
GL Q + +A R P E + + P+ + + Q++
Sbjct: 14645 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14704
Query: 426 -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
K +K V G PKP V W +G + +Q + A S L + + DSG
Sbjct: 14705 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 14763
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522
Y TA N G++ T+QV + P F V D
Sbjct: 14764 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 14802
Score = 62.4 bits (150), Expect = 4e-09
Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569
AP +KD G+ L C + G P+P I W G+ + +R + + L
Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24219
Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628
+ ED G YTC+A N +G+V S S+ LL P P P+ +
Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24266
Query: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
+ GS + + V G P P + W H +Q SE+ E L ++ V +
Sbjct: 24267 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24322
Query: 689 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
G Y + N G V A+L V+ +P + P + A L S +IS
Sbjct: 24323 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24371
Score = 62.0 bits (149), Expect = 5e-09
Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I +D G +TC VN +G S S L++Q + F +ET A VT
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003
Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
+ E K ++S + + + Q G P A
Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035
Score = 62.0 bits (149), Expect = 5e-09
Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329
+++ + V + TI + H + ++ +NK G + + +
Sbjct: 9884 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9943
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383
P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A
Sbjct: 9944 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 10002
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
S+ V L+ +Y+FRV AIN G S S+ T + P
Sbjct: 10003 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 10050
Score = 62.0 bits (149), Expect = 5e-09
Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y AKN +G A+ S V V D P P +L T+ + T+
Sbjct: 11606 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11649
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
+ P D G IT +++RK Q+ +
Sbjct: 11650 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11680
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340
+ L A E+ + + ENK+G ++ + + +D+P P A
Sbjct: 11681 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11738
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
D + + L W YDGGS SY +E + W+ + + + T + V + +
Sbjct: 11739 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11797
Query: 1399 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
Y+FRV+ N G S+ + E+ V E ++P ++++S
Sbjct: 11798 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11836
Score = 61.6 bits (148), Expect = 7e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)
Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143
T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++
Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149
Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194
+SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA +
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209
Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238
+ E + R + + S ATV+ K P+ PPK + PP
Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269
Query: 1239 QI 1240
I
Sbjct: 270 SI 271
Score = 61.6 bits (148), Expect = 7e-09
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
II D ++T A N G ++ + L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505
Score = 61.6 bits (148), Expect = 7e-09
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 1308 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364
+ ++ EN G + + +D DPP G P +I ++TL W Y GG +
Sbjct: 14959 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 15017
Query: 1365 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421
SY +E D N W + F V L D Y+FRV A N G S PS+ S+
Sbjct: 15018 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 15077
Query: 1422 TTVGEKPEEPKDEVEVSDDD 1441
T + E PK +V+V D
Sbjct: 15078 ITCRDDVEAPKIKVDVKFKD 15097
Score = 61.6 bits (148), Expect = 7e-09
Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
PAFK V G+ L + P + W + LK T + + ++I
Sbjct: 15776 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15835
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+ A ED G Y N AG+A + V V D P PP +
Sbjct: 15836 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15877
Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
D T PP K G S+ + V T TW
Sbjct: 15878 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15919
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331
S ++ TI A R + GC + + EN+ G S TV P
Sbjct: 15920 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 15966
Query: 1332 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387
P GTP + S+ + W DGGS V Y +E + + W +L T
Sbjct: 15967 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 16026
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
F L EY+FRV A N+ G +PS+ SE V P +P E +
Sbjct: 16027 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 16085
Query: 1448 DYRTVTINTEQKVSDFYDIEERLGSGKF 1475
++ T + K++ + ++ L G++
Sbjct: 16086 QWKKPTYDGGSKITGYIVEKKELPEGRW 16113
Score = 61.6 bits (148), Expect = 7e-09
Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P +K + VH E K+ + P TI W + L T + + S+S+
Sbjct: 16175 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16231
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+ A+ D G Y AKN AG+ + V V D P PE P V+
Sbjct: 16232 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16274
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275
S T +K PP II + +++ E+ L V Q ++C
Sbjct: 16275 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16324
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330
KV G++ T + ++ NK G + + VV K
Sbjct: 16325 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16364
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388
PD P P + + S+ + W + DGGS + Y +E D W
Sbjct: 16365 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16423
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
V L+ +H+Y+FRV A N G SEPS S
Sbjct: 16424 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16454
Score = 61.6 bits (148), Expect = 7e-09
Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
W+K K + K + G + + + G +G V
Sbjct: 18179 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18229
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388
P P G P A I +++TL W +YDGGS + Y +E D + W + T
Sbjct: 18230 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18289
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
F V L+ D Y+FRV A N G SEPS S T ++ + P ++
Sbjct: 18290 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18338
Score = 61.6 bits (148), Expect = 7e-09
Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W +
Sbjct: 21773 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21828
Query: 1381 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435
+ + R T F V L +EY+F V A N G S S L E P P V
Sbjct: 21829 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21888
Query: 1436 EVSDDDEKEPEVDY 1449
+V+D + +++
Sbjct: 21889 KVTDTSKTTVSLEW 21902
Score = 61.2 bits (147), Expect = 9e-09
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC
Sbjct: 18630 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18686
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
+ F V L + EY FR+ AIN G EP+ E+ E P+ E++
Sbjct: 18687 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18738
Score = 61.2 bits (147), Expect = 9e-09
Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+HV G+ + L ++ PP W G L+ ++ + + + ++I + D G
Sbjct: 23376 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23435
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223
Y KN G + +V + D P P+ E DAT +
Sbjct: 23436 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23480
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
+P P+ A + +++ + + G + ++ +T + KF + + +E+
Sbjct: 23481 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23530
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
+ + A + G Y +++++ ++ + + P PP T D+
Sbjct: 23531 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23571
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396
+TL+WY DGGS V Y +E W NK + RST L
Sbjct: 23572 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23626
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432
EY+ RV AIN G+ +PS+ S+ + KP+ P+
Sbjct: 23627 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23668
Score = 60.5 bits (145), Expect = 2e-08
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T
Sbjct: 13217 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13275
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
F V L+ D +Y+FRV A+N G S+PS
Sbjct: 13276 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13304
Score = 60.5 bits (145), Expect = 2e-08
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 1325 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
+ ++P PP D SS L+W +DGGS + Y +E+ + W E
Sbjct: 22168 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22226
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
+ +F V+ L+ EY+FRV+A N G SEP + + E EP
Sbjct: 22227 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22273
Score = 60.5 bits (145), Expect = 2e-08
Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P + + K + + C++ G P P++ W+ G + Q ++ D +H L
Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 24219
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
++ D G Y+C A+N G++ S L ++ A + P + K + G L
Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 24276
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589
G PVP +TW + +Q + + T E H+ ++ + H G Y N
Sbjct: 24277 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24336
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G V V + +K P KPT PI ++ L + + +S
Sbjct: 24337 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 24373
Query: 650 PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702
PP + W+ N E +E ++ + C E+ G Y A N+ G
Sbjct: 24374 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 24433
Query: 703 ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
+ +V+ ++ P + +P KP ++TA SC +A P
Sbjct: 24434 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 24475
Score = 60.5 bits (145), Expect = 2e-08
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G
Sbjct: 26475 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26533
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
F L IH D G YTC N +G+ + +LT++
Sbjct: 26534 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26570
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384
V KP PP G P D SS++++W YDGGS + Y +EI W+ + A
Sbjct: 15381 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15439
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
++TS+ + L + EYK R+ A+N G EP+
Sbjct: 15440 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15471
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
W K K + MKV + G Y + EN G + + V
Sbjct: 19261 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19309
Query: 1331 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386
DP P G P ++I S++L W YDGG+ + Y +E + + W + +
Sbjct: 19310 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19369
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D
Sbjct: 19370 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19425
Score = 59.7 bits (143), Expect = 3e-08
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
EK P F K + + ++ G A + G P P++ WF + + S ++ +D D
Sbjct: 3576 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3635
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
+ SLII +D+ +YTC A N G+ C+A L + + EG + E E
Sbjct: 3636 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3684
Score = 58.9 bits (141), Expect = 4e-08
Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
D L I++ +D+ YT A N++G+ + TA L +E + E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFE 3394
Score = 58.9 bits (141), Expect = 4e-08
Identities = 75/315 (23%), Positives = 117/315 (37%), Gaps = 29/315 (9%)
Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
++ + DS + +P ++ E++ + EVS +L+ TPV + S V
Sbjct: 4265 LQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVS 4324
Query: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524
++ L + + +S + S T A ++ + E + E P + L D
Sbjct: 4325 DEKQDESLKPSEEK-EESSSESGTEEVATVKIQ-----EAEGGLIKEDGPMIHTPLVDTV 4378
Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDH-GT 580
EG L S+ T + W + + + + + L I EDH G
Sbjct: 4379 SEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4436
Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
Y C A N G+ + SA +TV K AP+ + + L+V G
Sbjct: 4437 YVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIEPLEVALGHLA 4479
Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
T ++ P W G EI ES+ SL I D G YTC+A N
Sbjct: 4480 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4539
Query: 701 AGEVRTQAVLTVQEP 715
G V A LTV P
Sbjct: 4540 YGSVSCTATLTVTVP 4554
Score = 58.9 bits (141), Expect = 4e-08
Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)
Query: 1131 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189
W T+K TK + EGSL +++ A+N GQ++ + ++D
Sbjct: 7758 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7801
Query: 1190 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249
+ +++T + PP D T + PPK I ++ ++K
Sbjct: 7802 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7852
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
R G W+K K + +V + G+++ + G
Sbjct: 7853 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7893
Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
+G + ++ P P P +D + ++W +GGS + Y
Sbjct: 7894 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 7947
Query: 1367 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
+E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE
Sbjct: 7948 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 8007
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456
+ +P ++E D E E V +R V + T
Sbjct: 8008 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 8045
Score = 58.9 bits (141), Expect = 4e-08
Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G+ L+ V P TI W K ++ + + + ++ A+ D G Y
Sbjct: 17265 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17324
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
A N AG V V D P P V G S+ K
Sbjct: 17325 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17367
Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
+PP I + +++ E+ L V ++ +T
Sbjct: 17368 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17403
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343
N K+T L E+ + ++ NK G + + V+ K P PP ++I
Sbjct: 17404 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17458
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401
S+T+ W DGGS + Y +E D + W + R T V L DHEY+
Sbjct: 17459 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17518
Query: 1402 FRVRAINVYGTSEPS 1416
FRV A N G EPS
Sbjct: 17519 FRVSAENAAGVGEPS 17533
Score = 58.5 bits (140), Expect = 6e-08
Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V E + +F C ++ + V W +G + + ++ D H L + ++ D G
Sbjct: 5125 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 5181
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+ + +G+ + + RL V + F S L+D V EG+ C + +
Sbjct: 5182 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 5231
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
+ W N + +R+ + + H + + E L +S V E
Sbjct: 5232 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 5279
Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
S+ + + L P F L D ++ ++T+ +VS + P V W +G EI
Sbjct: 5280 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 5330
Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
S + + G + L I++ +D G Y C+ G +T+A +TV+ + +
Sbjct: 5331 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 5381
Query: 725 SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781
KP V +G++ ++ P VH W G+ L + E++++ L+L
Sbjct: 5382 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 5437
Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827
Q G+ N + +V + S + + REP +
Sbjct: 5438 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 5497
Query: 828 CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884
L G + G DR+ ++ G + ++ ED + + +HT
Sbjct: 5498 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 5550
Query: 885 --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938
E IR + + L +D+ K+ V T LS D+++ + + N QR ++V
Sbjct: 5551 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 5602
Query: 939 S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997
S ++E K HS + F+ L+ TS+ V + + KL G
Sbjct: 5603 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 5645
Query: 998 S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055
+ + + VE + + + S PV K + +KP NA
Sbjct: 5646 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 5692
Query: 1056 DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112
+K+ K+ LKK +K+D+ GT + + + + L V V E
Sbjct: 5693 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 5749
Query: 1113 KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ + ++S D W L G+ L T + +EG + S+ + + G
Sbjct: 5750 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 5802
Score = 58.5 bits (140), Expect = 6e-08
Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)
Query: 1090 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147
R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + +
Sbjct: 18327 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18386
Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207
++ ++ + D G Y N G V V D P P
Sbjct: 18387 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18433
Query: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267
V G ++ P A + II+ E ++
Sbjct: 18434 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18475
Query: 1268 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+W + ++Q + K+T L E+ + ++ NK G + + V
Sbjct: 18476 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18521
Query: 1328 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381
KP P TP S I S+ ++W DGG+ ++ Y +E D W +
Sbjct: 18522 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18581
Query: 1382 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
T V L H Y+FRV A N G EPS+ S
Sbjct: 18582 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18619
Score = 58.5 bits (140), Expect = 6e-08
Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T +
Sbjct: 24159 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24217
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + +ED G YTC ATN G + + +L ++ + G P+ K G
Sbjct: 24218 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24268
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
G R GRP P +TW G LQ S +++
Sbjct: 24269 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24306
Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
L + V + G Y + N G ++ IQ D V E N
Sbjct: 24307 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24366
Query: 269 SDV 271
S V
Sbjct: 24367 SAV 24369
Score = 58.5 bits (140), Expect = 6e-08
Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386
+KP P G P + + S ++W + DGG+ +++Y +E + W + T R
Sbjct: 24451 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24509
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE
Sbjct: 24510 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24560
Score = 58.5 bits (140), Expect = 6e-08
Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156
P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++
Sbjct: 25423 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25482
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214
I LPED G Y+ A N AG C + V+ + K+ E R + + L
Sbjct: 25483 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25542
Query: 1215 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250
GTES +A V KPA T K +I + E++K+R
Sbjct: 25543 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25597
Score = 57.8 bits (138), Expect = 1e-07
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1816
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+IS DD +YT N GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 1e-07
Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
+ ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V
Sbjct: 17815 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17874
Query: 1366 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
Y +E+ + W +A + + V L EY+FRV+A N G S+P
Sbjct: 17875 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17924
Score = 57.8 bits (138), Expect = 1e-07
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 1739 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25401 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25460
Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25461 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25520
Query: 1856 GEGEEEEE 1863
E + +EE
Sbjct: 25521 QEFKSKEE 25528
Score = 57.4 bits (137), Expect = 1e-07
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1816
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 57.4 bits (137), Expect = 1e-07
Identities = 96/428 (22%), Positives = 149/428 (34%), Gaps = 56/428 (13%)
Query: 1090 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1149
+ E G P+F Q L + V G+ + +VS P I W N + + TK ++ E
Sbjct: 3411 KKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFE 3470
Query: 1150 GS--LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV-DDAPAS------ENTKAPE 1200
S + + I A E G Y C A N AG+A C+ +TV AP S E E
Sbjct: 3471 ESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEME 3530
Query: 1201 MK----------------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFP 1244
MK + S + L S++ V P K P I+
Sbjct: 3531 MKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEV 3588
Query: 1245 EDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEH 1304
+ + G+ L V G W + S K + L IL + E
Sbjct: 3589 SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLED 3648
Query: 1305 CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY------- 1357
G YT + N G L + K + T S + S L +
Sbjct: 3649 EGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKP 3708
Query: 1358 ----DGGSAVQSYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHE 1399
G A+ Y++ + TW K+L T S +F V D +
Sbjct: 3709 IRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDS 3768
Query: 1400 YKFRVRAINVYGTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455
+ +A N+ G S + E E T + + P + K E +D + P ++
Sbjct: 3769 GLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALD 3828
Query: 1456 TEQKVSDF 1463
+EQ+++ F
Sbjct: 3829 SEQEIATF 3836
Score = 57.4 bits (137), Expect = 1e-07
Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
V KP PP D +S+TL+W YDGGS + Y +EI + + W+ +
Sbjct: 17545 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17603
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1442
R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E
Sbjct: 17604 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 17657
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Query: 1302 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358
QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D
Sbjct: 18891 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 18950
Query: 1359 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q
Sbjct: 18951 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19009
Score = 56.6 bits (135), Expect = 2e-07
Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%)
Query: 921 EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 978
E+MD + Q+ V+P T E E K + S ++V + +V ++ K TPV + V +
Sbjct: 4267 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4325
Query: 979 P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 1033
S+ ++K + + S + E K E+ L + GP+ P+ + E
Sbjct: 4326 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4383
Query: 1034 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1083
+ NAK DE K + V + VN + H G
Sbjct: 4384 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4442
Query: 1084 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1138
T + K + + AP K+K++ + VA G C++ S P W G+ +
Sbjct: 4443 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4502
Query: 1139 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1198
+ + + S+ I + D G Y C A N+ G C+ +TV P E
Sbjct: 4503 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4561
Query: 1199 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
+ R+P+ VL + ++K+P PK PK + PE + E V
Sbjct: 4562 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4617
Query: 1256 EL 1257
E+
Sbjct: 4618 EV 4619
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y
Sbjct: 10164 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10221
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
+AKN+AG+ + + V V D P T P + S
Sbjct: 10222 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10261
Query: 1229 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
++ F PED G PIT ++ +++ V
Sbjct: 10262 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10295
Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341
+ T+ Q + + EN +G + +A V + P+ P
Sbjct: 10296 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10354
Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399
++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L
Sbjct: 10355 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10414
Query: 1400 YKFRVRAINVYGTSEPS 1416
Y++RV A+N+ G +PS
Sbjct: 10415 YEYRVSAVNIVGQGKPS 10431
Score = 56.6 bits (135), Expect = 2e-07
Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + ++ V P T+ W + LK T+ + + ++I + + D G Y
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14767
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A+N G+ + V D P PP + D
Sbjct: 14768 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14798
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
+ + F D G V Q + TW++ + + +
Sbjct: 14799 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14847
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
++LT Q + + +N+ G + +V P PP GTP + +
Sbjct: 14848 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14901
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV
Sbjct: 14902 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 14961
Query: 1405 RAINVYGTSEPSQESE 1420
A N+ G S+PS+ SE
Sbjct: 14962 IAENMAGKSKPSKPSE 14977
Score = 56.6 bits (135), Expect = 2e-07
Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)
Query: 1057 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115
E L ++ E + KND A ++ K + + TA Q + G
Sbjct: 22234 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22293
Query: 1116 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
+ +S P + W L LK T + ++ +++++ ++ D G Y +N
Sbjct: 22294 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22353
Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
AG S V V P P + V +++ V PK
Sbjct: 22354 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22400
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
+ I++ E T W ++ ++ K+
Sbjct: 22401 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22430
Query: 1296 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351
T L E+ + + EN+ G S+ + + + P P P + + ++++++
Sbjct: 22431 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22488
Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N
Sbjct: 22489 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22548
Query: 1410 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
G S+ S+ S + + P + EV+D
Sbjct: 22549 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22577
Score = 56.2 bits (134), Expect = 3e-07
Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387
P P P +D S +L+W YDGG + Y +E ++ W + T R T
Sbjct: 14300 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14359
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+
Sbjct: 14360 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14410
Query: 1448 DYRTVTINTEQKVSDFYDIEER 1469
RT+ + + F I+ R
Sbjct: 14411 -RRTLVVRAGLSIRIFVPIKGR 14431
Score = 55.8 bits (133), Expect = 4e-07
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 1726 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1783
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1784 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878
Query: 1844 AELIVETMEE 1853
+L ++ E+
Sbjct: 1879 VKLEIQQRED 1888
Score = 55.8 bits (133), Expect = 4e-07
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 1306 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
GC + ++ EN+ G + V + P PP DI S+++L+W +DG
Sbjct: 14562 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14620
Query: 1360 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
GS + Y IE + W + T + V++L EY F+V A+N G S P +ES
Sbjct: 14621 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14679
Query: 1420 ELTTVGEKPEEPK 1432
V E+ P+
Sbjct: 14680 RPVIVKEQTMLPE 14692
Score = 55.5 bits (132), Expect = 5e-07
Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
AP F Q LQ V V EG + +S P + W +G+ + T+ + +S
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
++I + G Y A N +GQA + ++ V A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
PP +Q + VR G V L +VTG + +
Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
+IQ S ++ + L I A E G Y++ N +G + L V + + P
Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Query: 1335 A 1335
A
Sbjct: 201 A 201
Score = 55.5 bits (132), Expect = 5e-07
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1812
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24552 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24611
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
LII+ V DD Y +A N G + TA L VE
Sbjct: 24612 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24648
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26820
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26821 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26856
Score = 55.1 bits (131), Expect = 6e-07
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388
P PP P +D SS L W DGGS V Y +E + + W++ R T
Sbjct: 10050 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 10107
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D
Sbjct: 10108 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10160
Score = 55.1 bits (131), Expect = 6e-07
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386
KP P P D + L W DGGS + Y +E W + R
Sbjct: 11430 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11489
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
+F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D
Sbjct: 11490 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11544
Score = 55.1 bits (131), Expect = 6e-07
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268
TES + K K P PP++ + +++ E G +TG + +
Sbjct: 12010 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 12067
Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
W+ K MKV+N +H + + EN++G + + V
Sbjct: 12068 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 12116
Query: 1329 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378
DP P G P D S+TL W YDGG+ + Y +E+ S ++ W
Sbjct: 12117 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12176
Query: 1379 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
K A F V L + EY+FRV A N G P++ E E E P+ ++
Sbjct: 12177 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12236
Query: 1436 EVS 1438
+ S
Sbjct: 12237 DAS 12239
Score = 55.1 bits (131), Expect = 6e-07
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399
D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L +
Sbjct: 23273 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23332
Query: 1400 YKFRVRAINVYGTSEPSQESELTTV 1424
Y FR+RA N G SEP + TV
Sbjct: 23333 YLFRIRAQNEKGVSEPRETVTAVTV 23357
Score = 55.1 bits (131), Expect = 6e-07
Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567
AP F L++ V + L C V G P P + W G+ I +Y + G +
Sbjct: 24555 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24614
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I +D Y A N G VS +A + V P+K P L+
Sbjct: 24615 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24660
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP
Sbjct: 24661 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24716
Query: 688 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734
+D G Y A N G + V V +P G + +S+ + AS
Sbjct: 24717 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24776
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA 760
G S + + + WLR G+A
Sbjct: 24777 GGSKITNYIVEKCATTAERWLRVGQA 24802
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383
PDPP I +++ LSW DGGS V Y +E WD + + W++
Sbjct: 9640 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9698
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431
F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P
Sbjct: 9699 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9745
Score = 54.7 bits (130), Expect = 8e-07
Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101
+ G + K + G P P + W+++ + + + L C + T L + + DR
Sbjct: 20513 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 20568
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
G Y + N G+ T+ + + G P+ KT+ E +W
Sbjct: 20569 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 20620
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204
K+ +V++ + R + + +KGN + +P
Sbjct: 20621 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 20680
Query: 205 ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260
SV KN G+ + + + VV A +++S ++ D + +
Sbjct: 20681 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 20740
Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
+ K T D R++VT + + + C+ G P +P
Sbjct: 20741 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 20786
Query: 321 KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378
K D P + + T SSITL ++ + G V GEE +
Sbjct: 20787 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20846
Query: 379 PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421
T + PG+ VS A + P+E P+
Sbjct: 20847 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 20906
Query: 422 -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478
S K + V+ G P P V W + + GS Y E+ S L +
Sbjct: 20907 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 20962
Query: 479 TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528
TR D+G Y T N G+ S T+ V ++L V V+ ++L D +I+G
Sbjct: 20963 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 21021
Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
++ + + TW + + + D + + LAEN
Sbjct: 21022 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 21072
Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637
+G E PV ++ API + D DG
Sbjct: 21073 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 21118
Query: 638 SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697
V V E W H G I ++ + Q Q L + + G
Sbjct: 21119 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 21175
Query: 698 WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
+ G + + ++ E P VT +G +V + G P P++ WL+D
Sbjct: 21176 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 21228
Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817
G L K++ + E+ TL +K + H G+Y ++L N V C V + +
Sbjct: 21229 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 21285
Query: 818 ALPRG 822
+ P+G
Sbjct: 21286 SKPKG 21290
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)
Query: 1308 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
+ + EN G S T+ P P GTP D+ ++TL W DGGS +
Sbjct: 21457 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21516
Query: 1366 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419
YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S
Sbjct: 21517 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21572
Query: 1420 ELTTVGEKPEEP 1431
+ ++ P
Sbjct: 21573 GIIMTRDENVPP 21584
Score = 54.3 bits (129), Expect = 1e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 1746 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 1806 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 1e-06
Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%)
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
G+ + +V K + R+ + G R KF S + Q VKE +T F CE+S K V W
Sbjct: 5180 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 5234
Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
F + ++ + + +H L + + D +L
Sbjct: 5235 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 5284
Query: 508 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565
V+E P F+ L D +E + L+C V VP + W +G+ I S G+
Sbjct: 5285 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 5342
Query: 566 AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
L I+ A +D G Y C G A VTV + + KP
Sbjct: 5343 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 5384
Query: 625 FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684
L ++V G +++S P W G + S D + G +H L +
Sbjct: 5385 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 5439
Query: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744
TG + +A N+ ++ A L V+E FI+ V C +
Sbjct: 5440 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 5491
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782
+ +P T WL+ + + D FE++++ ++V+K
Sbjct: 5492 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 5527
Score = 54.3 bits (129), Expect = 1e-06
Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158
F+ KL + G+ L + S P + W + L+ + I + +L I
Sbjct: 10452 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10507
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
KA D G Y V +N G + CQV V D P PPV
Sbjct: 10508 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10549
Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
D K P I +K G+ V + + + TC K K +
Sbjct: 10550 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10605
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
+ +++ ++EN Y + S +A+ V D PD P T
Sbjct: 10606 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10650
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395
D S ++W +DGG + +Y +E ++ +K W + T F V DLL
Sbjct: 10651 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10705
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448
+Y+FRV A N G +PS S+ + +P V D VD
Sbjct: 10706 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10758
Score = 54.3 bits (129), Expect = 1e-06
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QL PV++K L PP F V G+ + GRP
Sbjct: 15761 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15803
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A
Sbjct: 15804 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15857
Score = 54.3 bits (129), Expect = 1e-06
Identities = 26/77 (33%), Positives = 44/77 (57%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y
Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16928
Query: 232 TCLVVNGSGKASMSAEL 248
V N G+ + S E+
Sbjct: 16929 GITVANVVGQKTASIEI 16945
Score = 54.3 bits (129), Expect = 1e-06
Identities = 25/72 (34%), Positives = 40/72 (55%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G+ + + GRP+P ++W+K PL+ + RV+V E VL I N+DD G Y
Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010
Query: 232 TCLVVNGSGKAS 243
T N +G A+
Sbjct: 18011 TVTATNSAGTAT 18022
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1814
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25376
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25377 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 53.9 bits (128), Expect = 1e-06
Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 1736 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
+S + + A L V P +K + I LEV G A+F C+I+ P+ WFK
Sbjct: 4444 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4499
Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
+ I ES I + + SL I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4500 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4557
Score = 53.9 bits (128), Expect = 1e-06
Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16639
Query: 232 TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260
T + N SG + SA ++++ LD+ +
Sbjct: 16640 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 16697
Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311
V + +AT VTN K+D L+ A P + P A
Sbjct: 16698 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 16757
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363
PQPP + ++ + + T S I +Q + R L
Sbjct: 16758 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16816
Query: 364 LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411
+ + GEE K + PR P + ++D+V +
Sbjct: 16817 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 16857
Query: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
P + S V+ Q +K +SG PKP + W +G P+ +Q I V +
Sbjct: 16858 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 16914
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCS 499
L + + D G Y T +N GQ + S
Sbjct: 16915 LSIKETHKDDGGQYGITVANVVGQKTAS 16942
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26469 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26528
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26529 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26578
Score = 53.1 bits (126), Expect = 2e-06
Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R GRP P++TW + + +V + + L I +++D G
Sbjct: 17662 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17719
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D
Sbjct: 17720 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17771
Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328
AK KN +R + AN + + S K+E+ +
Sbjct: 17772 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17830
Query: 329 ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375
P + P L +TS+S+ + R G V + P G E K
Sbjct: 17831 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 17889
Query: 376 PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423
GL S KA N + +P+ + + P + +
Sbjct: 17890 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 17949
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
++ + +K V G P+P ++W +G P+ +Q + V E A S L + + D G
Sbjct: 17950 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 18008
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
Y+ TA+N+ G + + ++ V V P F V D VI
Sbjct: 18009 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 18052
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G
Sbjct: 21596 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21655
Query: 230 VYTCLVVNGSGKASMSAELSIQ 251
VYT N SG A ++ +Q
Sbjct: 21656 VYTVEAKNASGSAKAEIKVKVQ 21677
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24220
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24221 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24251
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
PT + + V G V + + ++G PPP W G++++ESE E
Sbjct: 23364 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23423
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734
L I+E DTG YT E N G T V+ + +P T P I + S+T S
Sbjct: 23424 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23483
Query: 735 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790
G + L + WL +++ + T F L + + + + G
Sbjct: 23484 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23543
Query: 791 QYEILLKNRVGECSCQVSL 809
Y L++ V EC + +
Sbjct: 23544 SY---LQSEVIECRSSIRI 23559
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
LVI +D G+YT N G + L E +
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131
Score = 52.4 bits (124), Expect = 4e-06
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 1730 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1789
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 15749 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15807
Query: 1790 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 15808 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15865
Score = 52.4 bits (124), Expect = 4e-06
Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280
K P TP PP+ P + SV L K G +T +++ ++ +
Sbjct: 23943 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 24002
Query: 1281 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332
H K + + +T L E+ + ++ +N +G S + + VV DKP
Sbjct: 24003 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 24060
Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390
P S I S+TL W DGG + Y +E S + WK+ + F
Sbjct: 24061 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 24119
Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438
+ LL EY+FRV A N G S P S +++LT+ GE P K+ +V+
Sbjct: 24120 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24171
Score = 52.4 bits (124), Expect = 4e-06
Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P F+ + ++ V+ C+V+G PKP V W+ +G + + E G ++
Sbjct: 24556 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24615
Query: 474 LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
++ + T D T Y A+N G +S + +L+VE A + + P + + G+
Sbjct: 24616 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 24674
Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587
++ G P P ITW GQ + + V P +D G Y A+N
Sbjct: 24675 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 24733
Query: 588 ALG 590
G
Sbjct: 24734 RFG 24736
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G
Sbjct: 25206 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25265
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
Y C VVN G+ S AEL ++G+ + R T
Sbjct: 25266 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25300
Score = 52.0 bits (123), Expect = 5e-06
Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
++ H+ G L L + P + W + T I ++ GS + I A ED
Sbjct: 10854 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10911
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
G+Y +N AG S +V V D P P+ + +S K
Sbjct: 10912 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 10959
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+P G SV V + W ++ H
Sbjct: 10960 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 10997
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341
+E L +AA EN+ G + DP P G P
Sbjct: 10998 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 11045
Query: 1342 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
D+ + ++L W DGGS + Y +E + + W + T + V L
Sbjct: 11046 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 11105
Query: 1400 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
Y+FRV+A N+ G P + EK P E++V
Sbjct: 11106 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11142
Score = 52.0 bits (123), Expect = 5e-06
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R
Sbjct: 21596 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21654
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G YT EA N SG+ + +++ V+ + K +G + G++ +
Sbjct: 21655 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21698
Score = 51.6 bits (122), Expect = 7e-06
Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%)
Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469
++A P F + QS V++ V+ + V+GIP P V ++ +G + + ++ ++
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158
Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
+ L + +A DSGTYS A+N+ G+ + + L V+
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 51.6 bits (122), Expect = 7e-06
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327
W K K + + H KV G + + EN G +
Sbjct: 20344 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20392
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
+D +PP +DI +S++LSW ++DGGS + Y +E D + W +
Sbjct: 20393 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20451
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417
T F + L + +Y+FRV A N G+ S PS+
Sbjct: 20452 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20484
Score = 51.2 bits (121), Expect = 9e-06
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385
+ P PP P +D S+++ L W +++GG + Y ++ W +
Sbjct: 8628 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8685
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
+ V+++ +YK RV A+N G P E++ TV E E P E++VS
Sbjct: 8686 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8737
Score = 50.8 bits (120), Expect = 1e-05
Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)
Query: 1125 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183
PP T+ W + K L + + S ++I + D G Y +N G+ + S
Sbjct: 20927 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 20986
Query: 1184 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238
V V D PA+ + SR + L PP++ S + ++K+ A K
Sbjct: 20987 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 21038
Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298
TW + + ++ SE
Sbjct: 21039 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 21064
Query: 1299 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356
+ +L EN++G + V + PA S D +S+ LSW
Sbjct: 21065 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 21115
Query: 1357 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
+DGGS + Y +E +TW ++ V L +FRV A N G S+P
Sbjct: 21116 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21175
Query: 1417 QESELTTVGEKPEEPKDEVEVSD 1439
+ TV E P EV++SD
Sbjct: 21176 TIGPI-TVKELIITP--EVDLSD 21195
Score = 50.8 bits (120), Expect = 1e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343
SE K+T L E+ + ++ EN G A L +P P G P +D
Sbjct: 21836 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21893
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401
++++L W +DGG + Y IE+ + W ++ C T + V DL EYK
Sbjct: 21894 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 21953
Query: 1402 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
FRV AIN G + + + ++ P+ +++ +
Sbjct: 21954 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 21990
Score = 50.1 bits (118), Expect = 2e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
G P + + VT LG++ +SC I G P P + W R GK L + + +++ +
Sbjct: 24158 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24216
Query: 778 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
TL + + G Y + N VGE L+LQ
Sbjct: 24217 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24251
Score = 49.7 bits (117), Expect = 3e-05
Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)
Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
S P E + E P F L + VK G +TG+P+P++TW K ++ L+
Sbjct: 7301 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7360
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
R+++ + I + D G Y VN G+A+ E+++
Sbjct: 7361 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7420
Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
D N S + D ++TN + + DS
Sbjct: 7421 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7455
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
P PP G P S+ +SW +GGS + Y +E + + W ++
Sbjct: 9227 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9285
Query: 1385 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439
+ FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D
Sbjct: 9286 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9343
Score = 49.7 bits (117), Expect = 3e-05
Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + L V PP I W+ L+ + + + E D G Y
Sbjct: 13336 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13395
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
+N G+ E + V V D P PPV T + + P
Sbjct: 13396 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13437
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
P II + ++ + K T C+ FR V N E
Sbjct: 13438 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13480
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348
G + + EN+ G V P G +RS SS
Sbjct: 13481 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13528
Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408
++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N
Sbjct: 13529 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13587
Query: 1409 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
G P SE+T V +D+V D D K
Sbjct: 13588 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13613
Score = 49.7 bits (117), Expect = 3e-05
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+
Sbjct: 16866 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16924
Query: 789 AGQYEILLKNRVGECSCQVSLM 810
GQY I + N VG+ + + ++
Sbjct: 16925 GGQYGITVANVVGQKTASIEIV 16946
Score = 49.7 bits (117), Expect = 3e-05
Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G
Sbjct: 18745 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18802
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
Y + N SG S +A ++++ LDS + +RE K + D ++TN
Sbjct: 18803 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18860
Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
I ++ + A + NC+ Q G S + + + E+ +
Sbjct: 18861 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18920
Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
+ P P + T +T A ++ E + G V + K + T
Sbjct: 18921 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 18980
Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431
GL G + V AA R P E KP + VK + +
Sbjct: 18981 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 19040
Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
K G P+ V W +G + ++ + V L + +A D GTY SN
Sbjct: 19041 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 19099
Query: 492 AQGQLSCSWTLQV 504
+ G ++ T+ V
Sbjct: 19100 SAGSITVPITIIV 19112
Score = 49.3 bits (116), Expect = 4e-05
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12992
Query: 230 VYTCLVVNGSGKASMSAELSI 250
YT N SG S + +L +
Sbjct: 12993 DYTITAENSSGSKSATIKLKV 13013
Score = 48.9 bits (115), Expect = 5e-05
Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)
Query: 1131 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D
Sbjct: 14041 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14100
Query: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
P PP S+ + +K TPP I + +++
Sbjct: 14101 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14140
Query: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310
E+ L W + IQ H+ + + G++ + H G
Sbjct: 14141 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14181
Query: 1311 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
G + +VD+ P P P S++ ++ T+SW DGGS + Y +
Sbjct: 14182 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14236
Query: 1369 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426
E + + W + V L Y+FRV A N G PS+ S+ + +
Sbjct: 14237 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14296
Query: 1427 K--PEEPKDEVEVSDDDEK 1443
P P V+D +K
Sbjct: 14297 AAYPPGPPSNPHVTDTTKK 14315
Score = 48.5 bits (114), Expect = 6e-05
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)
Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
I++T++++ P S P+T A +PPR L +K G + V G P P
Sbjct: 12895 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 12953
Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++
Sbjct: 12954 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 13010
Query: 121 LTV 123
L V
Sbjct: 13011 LKV 13013
Score = 48.5 bits (114), Expect = 6e-05
Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)
Query: 1325 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
+ +D PP P +D +S++L+W +GGS V Y IE+ W +
Sbjct: 23652 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23709
Query: 1383 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
C +T +++ H EY+FRV A N G EP++ V E E P E++
Sbjct: 23710 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23767
Score = 48.1 bits (113), Expect = 8e-05
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566
+ + PS ++ G+D ++ V G P P I+W+ +G+P+ Q R E A
Sbjct: 17936 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17995
Query: 567 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
LHI++ +D G YT A N+ G + + V V EK
Sbjct: 17996 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 18032
Score = 48.1 bits (113), Expect = 8e-05
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QLG PV+++ +E +PS+ E P F T VK + + GRP
Sbjct: 19008 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 19050
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ +
Sbjct: 19051 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 19108
Query: 249 SIQGLD 254
+I LD
Sbjct: 19109 TIIVLD 19114
Score = 48.1 bits (113), Expect = 8e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)
Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
C TN ELT + + + V ++ D S P+ T P I + PP+
Sbjct: 19362 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19417
Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
+ +VVK G++ + + I GRP P ++W K + ++ AR + + +L +
Sbjct: 19418 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19477
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ D G Y + N +G S++ +
Sbjct: 19478 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19507
Score = 48.1 bits (113), Expect = 8e-05
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)
Query: 1700 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1759
AV + + S M S + KS L++ + + ++ A LE + E+
Sbjct: 26123 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26182
Query: 1760 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
T+ R + V EG +ARF C +G P P V W + Q + S Q+ +
Sbjct: 26183 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26241
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ IS V D+ Y+ NS G+ L ++
Sbjct: 26242 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26279
Score = 47.8 bits (112), Expect = 1e-04
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1808
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.8 bits (112), Expect = 1e-04
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 1263 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322
G P+T ++ ++++ KV + + T+ Q + + NK G +
Sbjct: 7143 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201
Query: 1323 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376
VN+ T PDPP D ++S+ L+W DGGS ++ Y +E +
Sbjct: 7202 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7260
Query: 1377 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
W T V L Y +RV+A+N G S+PS+ +E + E P+ +
Sbjct: 7261 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7320
Query: 1436 EV 1437
+V
Sbjct: 7321 DV 7322
Score = 47.8 bits (112), Expect = 1e-04
Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%)
Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478
K ++ + G P P+ +W +G + ++G ++ EDA S + + + +
Sbjct: 9451 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9510
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531
+G YS TA N GQ + + ++V + L V ++ + +G D
Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 9569
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
++G + + T ++G+ C G + D L E + AEN G
Sbjct: 9570 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 9620
Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
V ++ ++R P+ P P +K+ G TV +S PP
Sbjct: 9621 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 9663
Query: 652 PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
+ W G + + + ++ + ++++ + +A
Sbjct: 9664 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 9722
Query: 699 NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756
N+AG + A + + P I + G +V I I G PFPT+ W +
Sbjct: 9723 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 9782
Query: 757 ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
D K H L +D TLV+ + + G Y I N +G S ++ L
Sbjct: 9783 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9839
Score = 47.8 bits (112), Expect = 1e-04
Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)
Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630
P D + +A NA+G +S S+ S ++ V P P + GL
Sbjct: 21548 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21597
Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
+ G + + V G P P V W +G EI++ + SL +++ +
Sbjct: 21598 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21654
Query: 691 GTYTCEAWNSAGEVRTQAVLTVQE 714
G YT EA N++G + + + VQ+
Sbjct: 21655 GVYTVEAKNASGSAKAEIKVKVQD 21678
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
+++P PP +SD SS+ L W DGGS + Y IE + W +
Sbjct: 6917 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 6975
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
++ V L ++Y +RV A N G S+PS+ T + EP ++ D
Sbjct: 6976 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 7030
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)
Query: 574 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632
+P++ T T L E A Q A V+ S S+ + +A + P + + S L
Sbjct: 12874 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 12933
Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689
V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D
Sbjct: 12934 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 12990
Query: 690 TGTYTCEAWNSAG 702
+G YT A NS+G
Sbjct: 12991 SGDYTITAENSSG 13003
Score = 47.4 bits (111), Expect = 1e-04
Identities = 25/82 (30%), Positives = 36/82 (43%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
+ KE R I G+P P V+W KG PL RVSV L ++ + D G
Sbjct: 13621 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13680
Query: 231 YTCLVVNGSGKASMSAELSIQG 252
YT + N +G + + + G
Sbjct: 13681 YTITLKNVAGTKEGTISIKVVG 13702
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T
Sbjct: 17936 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17995
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
L I +++D GKYT ATN +G + + V
Sbjct: 17996 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 1731 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 21560 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21619
Query: 1791 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21620 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677
Score = 47.4 bits (111), Expect = 1e-04
Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
I+ G+ + V G PEP++ W + + + + L G R T VI D G
Sbjct: 22687 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22744
Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
KYT N SG + V+V + V S G+ VS+ ++ +S P + I
Sbjct: 22745 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22803
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
+ T V+ EG+ S +T + +V + P P + +N
Sbjct: 22804 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22863
Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
+ G+ ++ G ++ ++ E+S +D + +R T+
Sbjct: 22864 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22923
Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
D R +VT+++ + C R + A NS+P S SC++
Sbjct: 22924 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 22966
Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
P +AP+ V+ T SI+L + + +G + E+ A
Sbjct: 22967 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 23024
Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420
R F +G + AA + ++G + + E +P
Sbjct: 23025 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 23081
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479
++ ++ +++ VSG P P + W +G + S + + S+ L ++ K
Sbjct: 23082 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 23137
Query: 480 RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
D+G Y+ A N G+ S + ++V + V EV+ ++ + I+G
Sbjct: 23138 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 23193
Query: 533 LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590
G PV I + T + I + + L EN G
Sbjct: 23194 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23247
Query: 591 --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
S V V E +P+ P+K L+V+D ++ T+T ++
Sbjct: 23248 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 23283
Query: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705
P L++G + GT+ + + + P E T T E +R
Sbjct: 23284 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23338
Query: 706 TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752
Q V EP + + R ++ G+ V + IAG P P
Sbjct: 23339 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 23398
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
W G L +++ V + V L +++ G+Y + LKN G S + +++
Sbjct: 23399 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 23457
Query: 813 NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
+ A ++ EP + GG G ++ + RPGW
Sbjct: 23458 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 23507
Score = 47.4 bits (111), Expect = 1e-04
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387
P PP G P + + W DGG+ + +Y ++ + + W + T
Sbjct: 22868 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22926
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
V L+ +Y+FRV A+N G SEPS+ S + E P
Sbjct: 22927 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 22970
Score = 47.4 bits (111), Expect = 1e-04
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
V + S S++ ++P +P E + + + I+ GA+ + V G P P
Sbjct: 23048 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 23105
Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V
Sbjct: 23106 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23162
Score = 47.0 bits (110), Expect = 2e-04
Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%)
Query: 988 KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 1045
++++ + +GS E + VES +S + S V K + +A ++
Sbjct: 4266 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4325
Query: 1046 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1105
K + KP E + +S E ++V V + G + P L
Sbjct: 4326 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4375
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1164
D EG + L +++ + W K + + + Q+ + ++ I+K ED
Sbjct: 4376 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4433
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
+G Y C A ND+G+ S ++TV K
Sbjct: 4434 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4458
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+ AP K E +V G + ++ + W K ++I ES+
Sbjct: 4459 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4508
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+ +S+ S L IL + CG YT N+ GS LTV
Sbjct: 4509 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4551
Score = 47.0 bits (110), Expect = 2e-04
Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%)
Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 810
V+W + K + D F+ LQ+++ +TLV+ KV H G+Y N G+ + L
Sbjct: 4397 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4455
Query: 811 LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 870
+ +A + R EP ++ G + ++R W G+ + E D +R
Sbjct: 4456 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4511
Query: 871 G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 917
+L+ +V + ++T +A + L G+K K L E K
Sbjct: 4512 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4569
Query: 918 IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 963
P E++ ++ L++ + +PK ++ KV P ++V+ +V ++
Sbjct: 4570 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4627
Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 1023
K P P KVP KPA P LPA E A+ P +P+
Sbjct: 4628 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4673
Query: 1024 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1083
PV P K A E KP G P + + + ++ + + G
Sbjct: 4674 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4728
Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1137
+ + + F ++++D+ + E G + +C VS P+T I W +G
Sbjct: 4729 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4785
Query: 1138 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
++ + +FI ++ L + ++ + D G Y CV + + + ++ V++ P
Sbjct: 4786 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4839
Score = 47.0 bits (110), Expect = 2e-04
Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)
Query: 1111 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169
EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+
Sbjct: 25209 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25268
Query: 1170 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228
C ND G+ ++ V + + RR T+KK K
Sbjct: 25269 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25308
Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285
T PP+ ++ GE+V +T TW K ++I+ ++ K
Sbjct: 25309 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25368
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334
E+ + +LTI + + YT++ NK G + LTV P P
Sbjct: 25369 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25428
Query: 1335 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
G +IR S + TL W DG +IEI +
Sbjct: 25429 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25479
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
+ +++D LP+ +RV A N G++ ++ + K +E K + E +K+
Sbjct: 25480 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25536
Query: 1445 PEVDYRTVTI 1454
+ R I
Sbjct: 25537 IDKTLRMAEI 25546
Score = 46.2 bits (108), Expect = 3e-04
Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+ + + +G A FE V G P P VTW + + + + + + G+ + +
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144
++ ED G Y C+A N G EL V P +K+ +
Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3819
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PAVE S + AT + ++K + + +++ + L +PL
Sbjct: 3820 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3874
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260
S+ E++ + + + C +NGS S L +Q + S ++F
Sbjct: 3875 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3923
Query: 261 VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ ET+A SD K + +S E +++SL + P+ G P
Sbjct: 3924 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 3977
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353
S +PP S L S + +P+ + T+ +TLQ Q
Sbjct: 3978 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 4020
Score = 46.2 bits (108), Expect = 3e-04
Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444
GLG D IP+E Q P E + E VK TV+F + G+P P
Sbjct: 11117 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 11169
Query: 445 VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504
W +G+ ++ E V D S L + RD+G Y T SNA G + + L V
Sbjct: 11170 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
LP KE + + + ++G P P V+W + P+ + R ++ T +L+++
Sbjct: 13615 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13673
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125
+ D GKYT N +G ++ T+ + V G
Sbjct: 13674 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13702
Score = 46.2 bits (108), Expect = 3e-04
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 1717 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1771
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 26309 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26368
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 26369 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26419
Query: 1832 K 1832
+
Sbjct: 26420 E 26420
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I +
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188
D G YK + G+ E +C ++V+
Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 6000 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6055
Query: 1814 CSLIISDVCGDDDAKYTCK 1832
L+I+ DD+A+Y+C+
Sbjct: 6056 RILVINKCLLDDEAEYSCE 6074
Score = 45.8 bits (107), Expect = 4e-04
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565
++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G
Sbjct: 21585 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21641
Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
L ++DA + G YT A+NA G V V +
Sbjct: 21642 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21678
Score = 45.4 bits (106), Expect = 5e-04
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 45.4 bits (106), Expect = 5e-04
Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%)
Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
RQ TV+ EG+ K V + G P ET+P E A +L G
Sbjct: 8687 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8741
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ + G+ R +TGRP P W K L RV + L I + D G
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8800
Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
Y N G +A L ++ + + + + D E+T I
Sbjct: 8801 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8860
Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
K++K+ + +E + + G + ++ + PP E D
Sbjct: 8861 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8920
Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
P T+P+ ++T S+ITL EPR+ G + E++R P
Sbjct: 8921 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 8976
Query: 382 FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423
PT + + D KA N +P+ Q D P + + +
Sbjct: 8977 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 9036
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478
+VK + V +V+G+P P++ W T + + ++++ ++ S L + KA
Sbjct: 9037 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9096
Query: 479 TRDSGTYSCTASNAQGQL 496
D GTY+ TASN G +
Sbjct: 9097 REDKGTYTVTASNRLGSV 9114
Score = 45.4 bits (106), Expect = 5e-04
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%)
Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567
+V P+FSS +V GQD ++ + G P P ITW +G P++ T +
Sbjct: 16859 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16914
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I++ +D G Y N +GQ + S + +K P P P+
Sbjct: 16915 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 16961
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPP 651
+S ++ +S NPP
Sbjct: 16962 DVS----------AESITLSWNPP 16975
Score = 45.4 bits (106), Expect = 5e-04
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
+ G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y
Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010
Query: 694 TCEAWNSAG-EVRTQAVLTVQEP 715
T A NSAG +V+ +++P
Sbjct: 18011 TVTATNSAGTATENLSVIVLEKP 18033
Score = 45.1 bits (105), Expect = 7e-04
Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+K G + E V G P P + W ++G+ + + + T +LV D G
Sbjct: 15101 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15159
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160
YT ATN G FAK + V G + V + + P
Sbjct: 15160 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15206
Query: 161 P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215
P K+ +V++ + R + + QVT LK L+ + RV K G+
Sbjct: 15207 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15265
Query: 216 -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256
VL ++ D + C S S ++ D A
Sbjct: 15266 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 15325
Query: 257 NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315
+ +++ K T +D+R +V+ + E + + A + SP +P
Sbjct: 15326 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 15385
Query: 316 PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366
PP + L++ + S A P+ S PE P A GL S
Sbjct: 15386 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 15444
Query: 367 SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423
+ + + GLG +V KA +R +P E + D+ K +
Sbjct: 15445 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 15499
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481
++ T++ + G P PEV W + E + ++ S Y L+ D
Sbjct: 15500 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 15553
Query: 482 SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
SG Y T N+ G S ++V + L V EV + ++ D +++G +
Sbjct: 15554 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15613
Query: 535 CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593
V R + + C ++ D L E Y LAEN G +
Sbjct: 15614 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 15662
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
A K S R P+ P K T +MD ++ +V +S P
Sbjct: 15663 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 15701
Query: 654 VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
H+G + +G+ + + C E T T + + V Q +
Sbjct: 15702 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 15757
Query: 713 QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
+P + P I+K + T G+ + + G P P V W +D L
Sbjct: 15758 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15816
Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
K T E+ L +K G Y + L N GE
Sbjct: 15817 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 15856
Score = 45.1 bits (105), Expect = 7e-04
Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)
Query: 1228 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284
P PP A P++ + +R E G I W+ K R I +
Sbjct: 22465 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22519
Query: 1285 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
KV E K+T L E+ Y L + +A + + D P G P +D+
Sbjct: 22520 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22578
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398
S+++L W +YDGGS V Y IE + + + W + F V L
Sbjct: 22579 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22638
Query: 1399 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
Y+FRV A N G S+ S+ + T ++ PK E++
Sbjct: 22639 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22677
Score = 44.7 bits (104), Expect = 9e-04
Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%)
Query: 656 WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
W+ +G+ I+ES F G L I +V D G YTC E + A L V+E
Sbjct: 4779 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838
Query: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
+ + VT GQ + +SC + + V W +DGK + + G
Sbjct: 4839 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 4893
Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810
+ L + AG Y + ++N ECS V ++
Sbjct: 4894 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 4929
Score = 44.7 bits (104), Expect = 9e-04
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386
P P G P D+ S+++L W +DGGS + Y +E W T
Sbjct: 12817 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12876
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
+ L +Y+FR A S PS+ S+ T+ + P+ ++ V+
Sbjct: 12877 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12928
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
L +K G T +F +RG P P W +G I + + ++ FS L I
Sbjct: 11148 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11204
Query: 100 DRGKYTCEATNGSGARQVTVELTV 123
D G+Y +N +G++ V V LTV
Sbjct: 11205 DTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)
Query: 601 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
+EK S + +PV A P F + V+ G + + V G P P V W +
Sbjct: 15753 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15812
Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718
++++ + E L I++ ED G Y + NSAGE + T V+ + +P
Sbjct: 15813 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15872
Query: 719 TQP 721
T P
Sbjct: 15873 TGP 15875
Score = 43.9 bits (102), Expect = 0.001
Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+V+ G R + GRP P+VTW K + + V + M L I +DD G
Sbjct: 12244 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12302
Query: 230 VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279
Y+ +VN +G+ ++ + + + S V +T +D +VT+ I
Sbjct: 12303 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 12362
Query: 280 SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311
++ + D A P P A++
Sbjct: 12363 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 12422
Query: 312 --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365
S+P PPR+ ++ + T P L+ K IT QP R V+
Sbjct: 12423 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 12482
Query: 366 ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413
G++ K R A + P G V +A + +P
Sbjct: 12483 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 12527
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
PK P+ +K + ++ V G P P W +G + V++ S L
Sbjct: 12528 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 12585
Query: 474 LLKARTRDSGTYSCTASNAQG 494
+ +DSG YS TA N+ G
Sbjct: 12586 IKDVTRKDSGYYSLTAENSSG 12606
Score = 43.9 bits (102), Expect = 0.001
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L
Sbjct: 12527 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12585
Query: 220 IHGVNQDDVGVYTCLVVNGSG 240
I V + D G Y+ N SG
Sbjct: 12586 IKDVTRKDSGYYSLTAENSSG 12606
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)
Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
VK V ++ +SK S +V P R D P + F+ ++EG +++G P
Sbjct: 9719 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9772
Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
P +TW + N +P+ T + ++D T +LVI D G YT A N
Sbjct: 9773 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9828
Query: 111 GSGARQVTVELTVEG 125
G + L V G
Sbjct: 9829 NLGTASKEMRLNVLG 9843
Score = 43.1 bits (100), Expect = 0.003
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 0.003
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1819
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9754 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9812
Query: 1820 DVCGDDDAKYTCKAVNSLGEAT 1841
D YT AVN+LG A+
Sbjct: 9813 QSRRSDTGLYTITAVNNLGTAS 9834
Score = 43.1 bits (100), Expect = 0.003
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
Y N SG A SA +++ LD + K TN V KE IS E+ LD+
Sbjct: 11606 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11656
Score = 43.1 bits (100), Expect = 0.003
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12516 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12575
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12576 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12616
Score = 43.1 bits (100), Expect = 0.003
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 1731 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1787
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 16145 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16201
Query: 1788 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 16202 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16260
Query: 1848 V 1848
V
Sbjct: 16261 V 16261
Score = 43.1 bits (100), Expect = 0.003
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390
P PP S + S+TL W DGGS + Y IE + + W +
Sbjct: 19611 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19669
Query: 1391 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421
V+ L EY++RV A N G S PS+ S L
Sbjct: 19670 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19702
Score = 42.7 bits (99), Expect = 0.003
Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)
Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150
+G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
+++++ ED+G Y V
Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293
Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
+ G ++ +K KP P I+Q DQKV G+ V+L KV+ + +
Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401
Query: 1331 PDP 1333
P
Sbjct: 2402 ITP 2404
Score = 42.7 bits (99), Expect = 0.003
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 1760 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1813
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4745 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4802
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
+I DV D +YTC E T TA+L+VE +
Sbjct: 4803 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)
Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
+ + TV G Q + V++K S P+ T P + PKF
Sbjct: 17204 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17262
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
+VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D
Sbjct: 17263 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17320
Query: 228 VGVYTCLVVNGSGKASMSAELSI 250
G Y N +G S + +
Sbjct: 17321 GGQYILRASNVAGSKSFPVNVKV 17343
Score = 42.4 bits (98), Expect = 0.004
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107
+KS K +++ K + + +N + H G + + T+ A F++ ++D+
Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021
Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167
V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G
Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080
Query: 1168 YKCVAKNDAGQAE 1180
Y VA + A+
Sbjct: 3081 YTVVAGGNVSTAK 3093
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
+K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y
Sbjct: 10858 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10915
Query: 232 TCLVVNGSGKASMSAELSI 250
+ V N +G ++S ++ +
Sbjct: 10916 SLTVENPAGSKTVSVKVLV 10934
Score = 42.4 bits (98), Expect = 0.004
Identities = 21/72 (29%), Positives = 34/72 (47%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++++ G R + GRP P++TW K NV L+ + + + L VN+ D G
Sbjct: 13331 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13390
Query: 230 VYTCLVVNGSGK 241
Y + N GK
Sbjct: 13391 KYILTLENSCGK 13402
Score = 42.4 bits (98), Expect = 0.004
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + + V G P P V W +++++ +FE T L I E D+G Y
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14767
Query: 697 AWNSAGEVRTQAVLTVQ 713
A N GEV V+T+Q
Sbjct: 14768 ARNIVGEVGD--VITIQ 14782
Score = 42.4 bits (98), Expect = 0.004
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576
KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+
Sbjct: 16178 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16237
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633
D G Y A+N G+ S VTV+ K R P P P+ + G++ K
Sbjct: 16238 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16284
Query: 634 -----VMDGSQVTMTVQVSGNPPPEVIW 656
+ DG + V ++W
Sbjct: 16285 AWKPPLQDGGSDIINYIVERRETSRLVW 16312
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16857 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16911
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
+L I + DD +Y N +G+ T + E++
Sbjct: 16912 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16946
Score = 42.4 bits (98), Expect = 0.004
Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 736 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795
+ + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+
Sbjct: 19038 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19096
Query: 796 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
+ N G + +++++ + P + SC+ +
Sbjct: 19097 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19132
Score = 42.0 bits (97), Expect = 0.006
Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158
F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I
Sbjct: 5915 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 5972
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
PED Y C DA + SC + V
Sbjct: 5973 DCTPEDIKTYTC----DAKDFKTSCNLNV 5997
Score = 42.0 bits (97), Expect = 0.006
Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E F N+ + E T K V P +V W++ + I GR+ + R
Sbjct: 6087 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6145
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
LVI H ED G Y C + +V V
Sbjct: 6146 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6176
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
E +F +K + + EG+ F C I+ P V W + + L+ +
Sbjct: 6177 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6226
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V +VL + D+G Y +V G A +A L++
Sbjct: 6227 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6264
Score = 42.0 bits (97), Expect = 0.006
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578
G+ + V G P+P+I W N I+ + EL I A+ ED
Sbjct: 9041 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 9100
Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKS 605
GTYT A N LG V + V V+++ S
Sbjct: 9101 GTYTVTASNRLGSVFRNVHVEVYDRPS 9127
Score = 42.0 bits (97), Expect = 0.006
Identities = 26/93 (27%), Positives = 39/93 (41%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
P+ + ++ + L V G+ V + G P P W +G+EI+ E + E
Sbjct: 11136 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11195
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
L I+ DTG Y N+AG LTV
Sbjct: 11196 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 42.0 bits (97), Expect = 0.006
Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%)
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
V G P P+V W G ++G +++ + +L + + DSG YS T N G+
Sbjct: 12258 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 12315
Query: 497 SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
+ ++V L V +V + V +G V V R TW
Sbjct: 12316 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 12373
Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
+ T E H+ + +P + + A N G V K S
Sbjct: 12374 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 12421
Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666
+ L S+P P + ++ +++T PP L +G +
Sbjct: 12422 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 12463
Query: 667 ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716
E+ R T++S+ ++++ TG + A N+ G + V E
Sbjct: 12464 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 12522
Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
+ P I P +T G+ + I + G P PT W + G+ + H V + +
Sbjct: 12523 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 12581
Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
L++K V +G Y + +N G + ++ +++ ++ P
Sbjct: 12582 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 12625
Score = 42.0 bits (97), Expect = 0.006
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+T G +V + + G P PTV W +DG L K ++ ++ TL L V +
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12991
Query: 790 GQYEILLKNRVGECSCQVSL 809
G Y I +N G S + L
Sbjct: 12992 GDYTITAENSSGSKSATIKL 13011
Score = 42.0 bits (97), Expect = 0.006
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
VV+ G R GRP P W K + L S R + + L + N++D G
Sbjct: 21996 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 22053
Query: 231 YTCLVVNGSGKASMSAELSI 250
YT V N SG S++ + +
Sbjct: 22054 YTLTVENNSGSKSITFTVKV 22073
Score = 42.0 bits (97), Expect = 0.006
Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639
+ LA+NA G +S + T + + EY AP K L G DL + GS
Sbjct: 22642 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22692
Query: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
+ + V G P P++IW E+ E + G + + I+ D+G YT N
Sbjct: 22693 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22752
Query: 700 SAGEVRTQAVLTVQEPHDGTQP 721
++G T+AV + + D P
Sbjct: 22753 ASG---TKAVSVMVKVLDSPGP 22771
Score = 42.0 bits (97), Expect = 0.006
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
T D ++ P E + G+ V ++ G + G+P+P++ W KG+
Sbjct: 22664 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22713
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
L +VS+ I ++ D G YT V N SG ++S + + LDS
Sbjct: 22714 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22768
Score = 41.6 bits (96), Expect = 0.007
Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
+N+ + E TA FE V + P + W +NG I +F + ++G L+I
Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899
Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
ED +YT N + +TV E+TV EG K L
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959
Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
V K+ GD F A + +++ E +F +
Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
+ V E + F C+++ P V W+K + LQ + R+ + ++ + L I D
Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078
Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
G YT + +G +A+L ++G D RS +E +
Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3111
Score = 41.6 bits (96), Expect = 0.007
Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V + Q + CE++ + +V W +G V + G I L + A D+GT
Sbjct: 4852 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 4909
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+ T NA L CS ++V V + ++D V + C + P
Sbjct: 4910 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 4963
Query: 545 ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
I W + +P + L I++A+PED Y E A +T
Sbjct: 4964 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 5019
Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
+ E R+ E L P+ D+ + + + ++S P W
Sbjct: 5020 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 5060
Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
G ++ S + G + L + +V + G +A N+ T A+LTV+E
Sbjct: 5061 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 5112
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
+ F + VT + C + + V W + G + K + F+++ + L
Sbjct: 5113 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 5169
Query: 780 VLKKVQPWHAGQY 792
V+ Q G Y
Sbjct: 5170 VINDSQFDDEGVY 5182
Score = 41.6 bits (96), Expect = 0.007
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6150
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1862
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6151 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6198
Score = 41.6 bits (96), Expect = 0.007
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
A+ ISK S S P + + E P + P+ + + G T + E V G P P +
Sbjct: 17228 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17285
Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
W R + I R C I+ T L++ D G+Y A+N +G++ V +
Sbjct: 17286 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17341
Query: 122 TV 123
V
Sbjct: 17342 KV 17343
Score = 41.6 bits (96), Expect = 0.007
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++VK G + GRP P V W K + L+ A V ++ L I N++D G
Sbjct: 19824 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19881
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
YT + N AS++ L ++ LD+ T T DV KE
Sbjct: 19882 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19920
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+K ++++ + V G P P V WF +G + ++ ++E+ + GS L + A G
Sbjct: 21598 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 21656
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514
Y+ A NA G ++V+ V P
Sbjct: 21657 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 21686
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1813
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 26955 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27013
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
+LII DV D YT N G + T + + ++
Sbjct: 27014 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27051
Score = 41.2 bits (95), Expect = 0.010
Identities = 24/96 (25%), Positives = 43/96 (44%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+C P + ++V EG+ P P V+W K ++ S R+++ +
Sbjct: 8012 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8071
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
LE+ + D G+YT + N G A+ S + + GL
Sbjct: 8072 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8107
Score = 41.2 bits (95), Expect = 0.010
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Query: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570
P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L +
Sbjct: 8015 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 8074
Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTV 600
++ D G YT EN LG + S V V
Sbjct: 8075 PKSVRADAGIYTITLENKLGSATASINVKV 8104
Score = 41.2 bits (95), Expect = 0.010
Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%)
Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454
VSK + P + QR P + K + EV+E V ++ G+P P + WF P
Sbjct: 9727 VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 9783
Query: 455 RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
++ + V D + L C L ++R D+G Y+ TA N G S L V
Sbjct: 9784 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9843
Query: 507 LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557
V P F SV D + +G + + R TW+ ++ +P
Sbjct: 9844 RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 9899
Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
C + +L L + +A+N G + + + ++ + +P AP
Sbjct: 9900 -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 9948
Query: 618 SKPT 621
KPT
Sbjct: 9949 DKPT 9952
Score = 41.2 bits (95), Expect = 0.010
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11143 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11201
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIV 1848
D +Y N+ G T L V
Sbjct: 11202 LRRDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 41.2 bits (95), Expect = 0.010
Identities = 23/80 (28%), Positives = 36/80 (45%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+ G++ ++ I G P P V W +DGK L + E+ TLV+K
Sbjct: 18345 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18404
Query: 790 GQYEILLKNRVGECSCQVSL 809
GQY + L N G S +++
Sbjct: 18405 GQYILKLSNVGGTKSIPITV 18424
Score = 41.2 bits (95), Expect = 0.010
Identities = 26/85 (30%), Positives = 34/85 (40%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V + G L+L V P IIWT K L + + L G + I+ D G
Sbjct: 22685 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22744
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191
Y KN +G S V V D+P
Sbjct: 22745 KYTLTVKNASGTKAVSVMVKVLDSP 22769
Score = 40.8 bits (94), Expect = 0.012
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Query: 604 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W
Sbjct: 7299 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7358
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+++ + E + ++ I + DTGTY EA N G R AV+ V
Sbjct: 7359 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7406
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 7323 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7381
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIV 1848
D Y +AVN G AT E+ V
Sbjct: 7382 KRSDTGTYIIEAVNVCGRATAVVEVNV 7408
Score = 40.8 bits (94), Expect = 0.012
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389
P PP + I ++ L W DGGS + +Y +E D K W+ + T + T
Sbjct: 7712 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7770
Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSE 1414
V L Y FRV A N G S+
Sbjct: 7771 TVTPLTEGSLYVFRVAAENAIGQSD 7795
Score = 40.8 bits (94), Expect = 0.012
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P IL P + IK G + E V G P P W + + + + + L+
Sbjct: 12527 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12585
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I V +D G Y+ A N SG +++ V
Sbjct: 12586 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12616
Score = 40.8 bits (94), Expect = 0.012
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%)
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
++ +A N +G +S L V +A + + P+F + V+ G+D + G P
Sbjct: 15746 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 15804
Query: 543 PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
P +TW + P+ Q R E+ + L I+DA ED G Y N+ G+ + V
Sbjct: 15805 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 15864
Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPI 624
V +K P PT P+
Sbjct: 15865 VLDK-------------PGPPTGPV 15876
Score = 40.8 bits (94), Expect = 0.012
Identities = 20/81 (24%), Positives = 39/81 (48%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G
Sbjct: 16181 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16240
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y N +G+ S++ + +
Sbjct: 16241 NYILKAKNVAGERSVTVNVKV 16261
Score = 40.8 bits (94), Expect = 0.012
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+
Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16927
Query: 104 YTCEATNGSGARQVTVEL 121
Y N G + ++E+
Sbjct: 16928 YGITVANVVGQKTASIEI 16945
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 17938 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17996
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I + DD KYT A NS G AT +IV
Sbjct: 17997 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/74 (31%), Positives = 33/74 (44%)
Query: 639 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
Q+ + V G P V W +G ++E+ + T SL I+E ED GTY
Sbjct: 19039 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 19098
Query: 699 NSAGEVRTQAVLTV 712
NSAG + + V
Sbjct: 19099 NSAGSITVPITIIV 19112
Score = 40.8 bits (94), Expect = 0.012
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)
Query: 711 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757
+V EP + T P + PR + G+ + I+ IAG P P + W +D
Sbjct: 19395 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19454
Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
G + ++ E++ ++ L +K GQY + LKN G S V+
Sbjct: 19455 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19504
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 5915 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 5972
Query: 1820 DVCGDDDAKYTCKA 1833
D +D YTC A
Sbjct: 5973 DCTPEDIKTYTCDA 5986
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ ++ G T + RV+G PEP +TW + G+ + R L + L I D
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11604
Query: 102 GKYTCEATNGSGARQ 116
GKY A N SG Q
Sbjct: 11605 GKYIISAKNSSGHAQ 11619
Score = 40.4 bits (93), Expect = 0.016
Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V+ QT++ V G P+P++ W EG + R E +++ +D L + +A D G
Sbjct: 11548 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 11606
Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
Y +A N+ G S + V + L V V ++ + + G + V
Sbjct: 11607 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 11666
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596
+P Q S + V + I+ + L + + AEN +G
Sbjct: 11667 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 11710
Query: 597 WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650
T+ K +L + P +P P +L + D + + ++ G
Sbjct: 11711 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 11758
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705
P + H ++ S+D+ +G+ + + + + N GE V+
Sbjct: 11759 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 11816
Query: 706 TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763
T+ V+ + D +P K V T G ++ + + G PFP V W +D A
Sbjct: 11817 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11873
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
+ ++ D L K + G+Y + N G
Sbjct: 11874 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11911
Score = 40.4 bits (93), Expect = 0.016
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
VK V V G P P V+W +GT ++ EG I++ L L +DSG
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 12993
Query: 485 YSCTASNAQGQLSCSWTLQV 504
Y+ TA N+ G S + L+V
Sbjct: 12994 YTITAENSSGSKSATIKLKV 13013
Score = 40.4 bits (93), Expect = 0.016
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%)
Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
S++ G ++ +++ R+++ P F + V G+ F L+ V G P+P I WL
Sbjct: 17236 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 17289
Query: 550 NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
+ I+ + + CE A L ++DA+ D G Y A N G S V V ++
Sbjct: 17290 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 17346
Query: 606 SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633
P P P+ + G++ K
Sbjct: 17347 -----------PGPPEGPVQVTGVTSEK 17363
Score = 40.0 bits (92), Expect = 0.021
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)
Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
DP+ V L E P IL R IK G T + ++G P P+VTW + +
Sbjct: 10827 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10886
Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ R +D G+ + +A H ED G Y+ N +G++ V+V++ V
Sbjct: 10887 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 10934
Score = 40.0 bits (92), Expect = 0.021
Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
VK T++ V G P PEVAW + T + R +++ A S L KA+ D
Sbjct: 11841 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 11899
Query: 483 GTYSCTASNAQGQLSCSWTLQV 504
G Y TA+N G T+ V
Sbjct: 11900 GKYVVTATNTAGSFVAYATVNV 11921
Score = 40.0 bits (92), Expect = 0.021
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)
Query: 598 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
V V+EK S +P VA P S V G + + V +SG P P + W
Sbjct: 16832 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16891
Query: 657 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715
+G ++++ + +L I+E +D G Y N G+ + ++T+ +P
Sbjct: 16892 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 16951
Score = 40.0 bits (92), Expect = 0.021
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575
KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D +
Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18401
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
D G Y N G S V V ++ P P P+ + G++
Sbjct: 18402 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18443
Score = 40.0 bits (92), Expect = 0.021
Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%)
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Q+ V+ +++ G P P W P +++ L +
Sbjct: 21993 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 22049
Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
D+G Y+ T N G S ++T++V + +V ++++ D +++G +
Sbjct: 22050 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 22109
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
V R +W Q C + +++ LAE
Sbjct: 22110 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 22149
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
SA V+E E P+ ++ AP L V+D S+ + +
Sbjct: 22150 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 22193
Query: 654 VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700
WL H+G Q+ DF E T Q + ++ + + + +A N
Sbjct: 22194 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 22251
Query: 701 AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
AG + + ++EP + T + +T G I I+G P P V W
Sbjct: 22252 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 22311
Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
+ L K+T + +D TL +K +G+Y + L+N G + V++++
Sbjct: 22312 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 22370
Query: 817 RAL-PRGREPASCED-LCGGGVGADGGGSD 844
P S E + G DGGG++
Sbjct: 22371 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22400
Score = 39.7 bits (91), Expect = 0.028
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103
G AKF ++ P + W + G+ I + C IR + SL I D G+
Sbjct: 4476 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4531
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
YTC+A+N G+ T LTV G+ V K L +R P E
Sbjct: 4532 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4574
Score = 39.7 bits (91), Expect = 0.028
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 1737 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 5619 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5677
Query: 1791 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5678 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5717
Score = 39.7 bits (91), Expect = 0.028
Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)
Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
PSR + ++ EAP L + L +K G + V G PEP++TW + +
Sbjct: 7300 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7359
Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
R ++ + ++ I D G Y EA N G VE+ V
Sbjct: 7360 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7408
Score = 39.7 bits (91), Expect = 0.028
Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V E + + +P P V+W +G V+ + + + D S +L + K+ D+G
Sbjct: 8026 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 8084
Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
Y+ T N G + S ++V + + ++ S + + +G +L +
Sbjct: 8085 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 8144
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
R T++ P+ + V +D +P + A N +G
Sbjct: 8145 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 8188
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
E PV P P D++V + + MT+ + PP L
Sbjct: 8189 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 8232
Query: 658 HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712
++G +G + C + + P TYT + E VR + +
Sbjct: 8233 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 8290
Query: 713 QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
EP T P P S+ G + + +I+G P+PT+ W++D
Sbjct: 8291 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 8344
Score = 39.7 bits (91), Expect = 0.028
Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L I+ G GR G P+P+V+W ++ + R + T +L D
Sbjct: 10456 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10514
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
GKY N +G+R+ ++ V + G PV + F + W
Sbjct: 10515 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 10566
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221
+K+ ++++ ++G+ V + + + +VS + + IH
Sbjct: 10567 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10615
Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273
N G+ LV + SM A+ + D+ ++ V E ++ D K
Sbjct: 10616 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 10668
Query: 274 EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317
+TN I ++ + S A +K+ C R + P PP
Sbjct: 10669 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 10728
Query: 318 RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373
+ +K K SP P+ S +T Q R + G V G+E R
Sbjct: 10729 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 10788
Query: 374 PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420
A P + P T+ G +D K + G+ D A K +P
Sbjct: 10789 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 10848
Query: 421 -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
+ Q +K T++ + G+P P+V W E + I+V GS L +
Sbjct: 10849 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 10905
Query: 476 KARTRDSGTYSCTASNAQGQLSCS 499
A D G YS T N G + S
Sbjct: 10906 NAAHEDGGIYSLTVENPAGSKTVS 10929
Score = 39.7 bits (91), Expect = 0.028
Identities = 23/81 (28%), Positives = 34/81 (41%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VVK G RF I G P P W ++ +V N VL I + D G
Sbjct: 11148 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11207
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y V N +G +++ L++
Sbjct: 11208 EYQITVSNAAGSKTVAVHLTV 11228
Score = 39.7 bits (91), Expect = 0.028
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
+++ A + + + P V EAP L + + ++ G +A+ +G P
Sbjct: 17621 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17680
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P++TW R T + ++ G+ T L I D GKY + N SG++ V
Sbjct: 17681 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17737
Query: 121 LTV 123
+ V
Sbjct: 17738 VKV 17740
Score = 39.7 bits (91), Expect = 0.028
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V + G L L VS PP I W+ G L + I ++ SL + ++K D G
Sbjct: 23084 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23141
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191
Y A+N +G+ + V V D P
Sbjct: 23142 KYTIEAENQSGKKSATVLVKVYDTP 23166
Score = 39.3 bits (90), Expect = 0.036
Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779
P F +SV G + I+G P P V W RDG+ + T ++ ++ L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839
+ V ++G+Y + N G+ + L+++ +A P + L +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116
Query: 840 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893
G R G P + DG +++ L ++ E
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 894 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953
++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D
Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231
Query: 954 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005
RS+ + G + +P K PP P P RS + K +L + S
Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287
Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032
S P+ + + P PV + PA
Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310
Score = 39.3 bits (90), Expect = 0.036
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 8004 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8063
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
D + L + D YT N LG AT + + V
Sbjct: 8064 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8104
Score = 39.3 bits (90), Expect = 0.036
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)
Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575
SV ++ G+ + V G PVP W + R + +EL I+DAL
Sbjct: 8737 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8796
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
+DHG Y A N+ G +A V V + +L + P + L SD +
Sbjct: 8797 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8851
Query: 636 DGSQVT 641
GS++T
Sbjct: 8852 GGSEIT 8857
Score = 39.3 bits (90), Expect = 0.036
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785
G + I I G P P W DGKA KD H E +N V +++ + +
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9510
Query: 786 PWHAGQYEILLKNRVGE--CSCQVSLM 810
H G+Y I KN+ G+ +C+V +M
Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVM 9537
Score = 39.3 bits (90), Expect = 0.036
Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 668 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
D HFE G H + + G ++ E S G + + V P P +
Sbjct: 16123 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16179
Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
++ G+S + I G P PT+ W++ + L +T E+ + +L +K
Sbjct: 16180 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16235
Query: 786 PWHAGQYEILLKNRVGECSCQVSL 809
+G Y + KN GE S V++
Sbjct: 16236 RVDSGNYILKAKNVAGERSVTVNV 16259
Score = 38.9 bits (89), Expect = 0.047
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ V G + + +V G P P++ W G + + Q + L I+E D G
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605
Query: 692 TYTCEAWNSAGEVRTQAVLTV 712
Y A NS+G + A++ V
Sbjct: 11606 KYIISAKNSSGHAQGSAIVNV 11626
Score = 38.9 bits (89), Expect = 0.047
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
SV A G+ V + G P PTV W +D K L D + + + L + +V
Sbjct: 20908 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 20966
Query: 789 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
G+Y + ++N VGE SS ++ PA+C+ L
Sbjct: 20967 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 21000
Score = 38.9 bits (89), Expect = 0.047
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584
G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT +
Sbjct: 21206 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21265
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
+NA+ +++ V L P PSKP PI
Sbjct: 21266 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21292
Score = 38.5 bits (88), Expect = 0.062
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
G E+ T + PAP P PP ++ ++ V GESV L ++G T TW +
Sbjct: 875 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
QI+ S ++ ++L I A E G +T N+ G+ L V
Sbjct: 933 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 38.5 bits (88), Expect = 0.062
Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 614 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
PV ++P P + + +++M G + + V+G P P +W E+ + +
Sbjct: 8720 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8778
Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
+ GT+ L I++ +D G Y A NS G
Sbjct: 8779 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8811
Score = 38.5 bits (88), Expect = 0.062
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
L +K G T + E VRG P P+V W ++ +T R +D + FSL
Sbjct: 11839 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11896
Query: 99 EDRGKYTCEATNGSGA 114
D GKY ATN +G+
Sbjct: 11897 SDGGKYVVTATNTAGS 11912
Score = 38.5 bits (88), Expect = 0.062
Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%)
Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
IP EG+ D+ K + ++ T++ V G P P++ W +R + G ++
Sbjct: 13317 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 13369
Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515
+ +L D+G Y T N+ G+ + ++V + V E++
Sbjct: 13370 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 13429
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+ V + +I+G ++ V+ R +W + T E + +
Sbjct: 13430 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 13480
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
+ AEN G + + +R + V S+ P+ DLKV
Sbjct: 13481 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 13521
Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691
S+ + ++ G P G+ I DF E+ Q SL +Q + T
Sbjct: 13522 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 13575
Query: 692 ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744
T+ A N GE T + +TV D P K A + + I
Sbjct: 13576 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13634
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
G P P+V W + L DT V + TL++ Q AG+Y I LKN G
Sbjct: 13635 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693
Query: 805 CQVSL 809
+S+
Sbjct: 13694 GTISI 13698
Score = 38.5 bits (88), Expect = 0.062
Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
PAF L + G K + G P P VTWH++ P+ R + L
Sbjct: 15776 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15834
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I ED G Y + TN +G T+ + V G + + D +
Sbjct: 15835 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15889
Query: 153 PSIWGECPPKF 163
WG PPK+
Sbjct: 15890 ---WG--PPKY 15895
Score = 38.5 bits (88), Expect = 0.062
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17260 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17318
Query: 1824 DDDAKYTCKAVNSLG 1838
D +Y +A N G
Sbjct: 17319 IDGGQYILRASNVAG 17333
Score = 38.5 bits (88), Expect = 0.062
Identities = 22/83 (26%), Positives = 37/83 (44%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ K G I+GRP P+VTW + L+ + RVS++ L + + D G
Sbjct: 22285 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22344
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y + N +G + S + + G
Sbjct: 22345 RYFLTLENTAGVKTFSVTVVVIG 22367
Score = 38.1 bits (87), Expect = 0.081
Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)
Query: 541 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
PV W+ +N +PI+ + E GV +P+ A NA+G
Sbjct: 7953 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 7996
Query: 600 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
+ S SE ++ P KPT + D+ V++G ++++ V P P V W
Sbjct: 7997 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 8050
Query: 659 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717
+G E++ S+ + L + + D G YT N G V + P
Sbjct: 8051 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 8108
Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771
P K +T S SC + +P P +H++ + + + T + V+
Sbjct: 8109 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8158
Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
E+ + +K + P + + N+VG
Sbjct: 8159 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8188
Score = 37.7 bits (86), Expect = 0.11
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
Query: 620 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672
PT + L D +KV G V + V+G P P++ W N I++ D
Sbjct: 9023 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 9082
Query: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
+ + L I + ED GTYT A N G V
Sbjct: 9083 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 9114
Score = 37.7 bits (86), Expect = 0.11
Identities = 20/73 (27%), Positives = 33/73 (45%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V++K G+ R ++GRP P + W K L+ +A++ + + L + D G
Sbjct: 15099 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15158
Query: 230 VYTCLVVNGSGKA 242
YT N G A
Sbjct: 15159 AYTLTATNPGGFA 15171
Score = 37.7 bits (86), Expect = 0.11
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
+AP L P+ + + G T E +RG P P V W ++G+ + + R + I+
Sbjct: 18331 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18390
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
T +LV+ D G+Y + +N G + + + + V
Sbjct: 18391 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18426
Score = 37.7 bits (86), Expect = 0.11
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)
Query: 617 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663
PS+ T PI ++ + D+K D G + + ++G P P + W +G EI
Sbjct: 19399 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19458
Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
+E L +++ DTG Y N AG
Sbjct: 19459 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19497
Score = 37.7 bits (86), Expect = 0.11
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
+ G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y
Sbjct: 21598 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21657
Query: 1169 KCVAKNDAGQAECSCQVTVDDAP 1191
AKN +G A+ +V V D P
Sbjct: 21658 TVEAKNASGSAKAEIKVKVQDTP 21680
Score = 37.4 bits (85), Expect = 0.14
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1825
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8798
Query: 1826 DAKYTCKAVNSLGEATCTAELIV 1848
+Y A NS G A + V
Sbjct: 8799 HGRYVITATNSCGSKFAAARVEV 8821
Score = 37.4 bits (85), Expect = 0.14
Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11604
Query: 790 GQYEILLKNRVG 801
G+Y I KN G
Sbjct: 11605 GKYIISAKNSSG 11616
Score = 37.4 bits (85), Expect = 0.14
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584
G + L +V G P+P ++W +G +P + + + + L + +D G YT
Sbjct: 12938 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12997
Query: 585 AENALGQVSCSAWVTVHEK 603
AEN+ G S + + V +K
Sbjct: 12998 AENSSGSKSATIKLKVLDK 13016
Score = 37.4 bits (85), Expect = 0.14
Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
VDP R+ P + + + G + K + + G P P + W + Q +++ R
Sbjct: 16166 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16217
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ T SL + D G Y +A N +G R VTV + V G V+S
Sbjct: 16218 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16276
Query: 139 TLGDR 143
++
Sbjct: 16277 VTAEK 16281
Score = 37.4 bits (85), Expect = 0.14
Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480
V+ + + G P PE+ W R+EG +V + G +Y L +
Sbjct: 17664 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 17716
Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
D+G Y N+ G S T++V + LAV EV + ++ + +I+G V
Sbjct: 17717 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 17776
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
+ R YA + + +++ + +AEN G
Sbjct: 17777 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 17824
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
V V + + +E P P K T + D SQ + ++ PE
Sbjct: 17825 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 17865
Query: 654 VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703
H+G + +GT+ +C V +G + +A+N G+
Sbjct: 17866 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 17921
Query: 704 VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
+ + D T QP + + G+ + I + G P P + W++DG+ L
Sbjct: 17922 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 17980
Query: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
K T V + L +K+ G+Y + N G + +S+++
Sbjct: 17981 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029
Score = 37.4 bits (85), Expect = 0.14
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 1740 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 19795 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19853
Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 19854 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19904
Score = 37.4 bits (85), Expect = 0.14
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ +
Sbjct: 20110 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20168
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
D G+Y A N SG + + + V G V+S
Sbjct: 20169 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20208
Score = 37.4 bits (85), Expect = 0.14
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y +
Sbjct: 21601 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21659
Query: 795 LLKNRVGECSCQVSLMLQNSSARAL 819
KN G ++ + +Q++ + +
Sbjct: 21660 EAKNASGSAKAEIKVKVQDTPGKVV 21684
Score = 37.0 bits (84), Expect = 0.18
Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)
Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137
+ H G + + P + V V EG+ +C+V+ P + W LNG+
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834
Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195
++ +K + +G + + I D G K A+N G E ++ + S
Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893
Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
+APE RP+ + + + +P T K + + + +KV ES
Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949
Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290
EL K + IT +K RK+ + E + K +E
Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009
Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340
G K+TI L+ E + + +G A + VV KPDP
Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400
WY + IE D W E C ++D+ +
Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101
Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451
V+AIN+ G + Q +L T ++ ++ KD + + + EP V +
Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161
Query: 1452 VTINTEQKVSDFY 1464
E D Y
Sbjct: 2162 YKDGMEVHEGDKY 2174
Score = 37.0 bits (84), Expect = 0.18
Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%)
Query: 935 PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994
P+ V E + K+ Q+ DFRSVL + P P+ P+F GK + +
Sbjct: 1871 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1916
Query: 995 NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054
+T K V K + + K E + + + T + A
Sbjct: 1917 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 1967
Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101
LKS K+E +++ + H T+ EK++ E + T P FK
Sbjct: 1968 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2027
Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152
+++Q V +G + +V P W NG K ++ + E ++
Sbjct: 2028 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2087
Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178
C + I ED A N AG+
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGE 2113
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + VSG PPP V W N NE ++ E S+ I+ G Y+
Sbjct: 10167 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10224
Query: 697 AWNSAGEVRTQAVLTV 712
A N AGE + ++ V
Sbjct: 10225 AKNEAGERKKTIIVDV 10240
Score = 37.0 bits (84), Expect = 0.18
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 1763 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1819
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11541 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11597
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTA 1844
+ D KY A NS G A +A
Sbjct: 11598 EAVRADHGKYIISAKNSSGHAQGSA 11622
Score = 37.0 bits (84), Expect = 0.18
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 1749 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1802
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11815 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11874
Query: 1803 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
++ D + S ++ D KY A N+ G A + V
Sbjct: 11875 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921
Score = 37.0 bits (84), Expect = 0.18
Identities = 22/92 (23%), Positives = 40/92 (43%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + G ++ + V G P P W +E+ S + + L I++V +D+G
Sbjct: 12536 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12595
Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723
Y+ A NS+G + + V + QP F
Sbjct: 12596 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12627
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16636
Query: 1827 AKYTCKAVNSLG 1838
KYT NS G
Sbjct: 16637 GKYTLTLENSSG 16648
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 1758 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20556
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
S++I D + Y K N++G A+ T
Sbjct: 20557 SILIKDADRLNSGCYELKLRNAMGSASAT 20585
Score = 37.0 bits (84), Expect = 0.18
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V + G + I+G+P P + W K + LQ +A V V + + I ++ + G
Sbjct: 20510 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20569
Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254
Y + N G A SA + +Q LD
Sbjct: 20570 CYELKLRNAMGSA--SATIRVQILD 20592
Score = 36.6 bits (83), Expect = 0.23
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)
Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
RF A E R + PK T +VV G+ P+ + W K N PL
Sbjct: 6610 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6669
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ +E+ ++LE + D G Y ++ N GKA L +
Sbjct: 6670 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6714
Score = 36.6 bits (83), Expect = 0.23
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
V+EG KI G P P +TW K P +P + V + N + V L I
Sbjct: 9756 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9814
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
+ D G+YT VN G AS L++ G
Sbjct: 9815 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9843
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586
G L ++G P P++TW + AR ++L I++A ED G Y+ E
Sbjct: 10861 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 10920
Query: 587 NALGQVSCSAWVTVHEK 603
N G + S V V +K
Sbjct: 10921 NPAGSKTVSVKVLVLDK 10937
Score = 36.6 bits (83), Expect = 0.23
Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643
A+N G +S + T + K EY P PT L + G + +
Sbjct: 13978 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 14028
Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
+ + G P P+ W G +I+ S+ T L I+ +D G YT A N G
Sbjct: 14029 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 14088
Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
+TV + P IS + A+L
Sbjct: 14089 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 14119
Score = 36.6 bits (83), Expect = 0.23
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y
Sbjct: 20116 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20175
Query: 694 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725
A NS+G + ++ + P T P IS
Sbjct: 20176 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20208
Score = 36.6 bits (83), Expect = 0.23
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 1743 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22259 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22317
Query: 1800 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22318 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22365
Score = 36.2 bits (82), Expect = 0.31
Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 1076 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128
NC+ G D N K S P + L+DV V G+ C++S +
Sbjct: 5795 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5853
Query: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
+ W L GK L+ + ++ EG + ++++ ED G + AK+
Sbjct: 5854 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5899
Score = 36.2 bits (82), Expect = 0.31
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%)
Query: 438 SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
SG PKP+V+WF + V ++ + + L +KA+ DSG Y N+ G
Sbjct: 10471 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 10529
Query: 498 CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
+ V V P SF V KD VI
Sbjct: 10530 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 10559
Score = 36.2 bits (82), Expect = 0.31
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
++ + G++ + + G P PT+ WLR K + +++ E+ + L++K
Sbjct: 17262 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17320
Query: 789 AGQYEILLKNRVGECSCQVSL 809
GQY + N G S V++
Sbjct: 17321 GGQYILRASNVAGSKSFPVNV 17341
Score = 35.8 bits (81), Expect = 0.40
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P T L V +EG + + IT + V W N + + + L I
Sbjct: 4368 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4425
Query: 221 HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250
VN +D G Y C +N SGK + SA+L++
Sbjct: 4426 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4456
Score = 35.8 bits (81), Expect = 0.40
Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
T S ++ + E ++ +A N G + ++ L V + D P
Sbjct: 8979 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 9023
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
++ R S+ G+ + VK G+ +TG P P++ W K ++
Sbjct: 9024 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 9073
Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
+ VS L I ++D G YT N G + + + S R+
Sbjct: 9074 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9133
Query: 261 VRETKA 266
V + KA
Sbjct: 9134 VTDIKA 9139
Score = 35.8 bits (81), Expect = 0.40
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G +V I G P PT W DG + K H+ V + L +K G+Y+I
Sbjct: 11153 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11211
Query: 795 LLKNRVGECSCQVSL 809
+ N G + V L
Sbjct: 11212 TVSNAAGSKTVAVHL 11226
Score = 35.8 bits (81), Expect = 0.40
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
EAP +L P L IK G T + G P P+ +W + G+ I +
Sbjct: 14002 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14061
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ + +A + D G+YT ATN G + V++TV
Sbjct: 14062 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 14097
Score = 35.8 bits (81), Expect = 0.40
Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584
G + ++ V G P P +TW Q ++ + A L+I + + D G Y
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14767
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
A N +G+V + VH+ P PT PI
Sbjct: 14768 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14794
Score = 35.8 bits (81), Expect = 0.40
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16638
Query: 104 YTCEATNGSGARQVTVELTV 123
YT N SG + V + V
Sbjct: 16639 YTLTLENSSGTKSAFVTVRV 16658
Score = 35.8 bits (81), Expect = 0.40
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P+ LP +K K + +G P+ V W ++GQ + R + + SL
Sbjct: 19023 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSS-KTVTSLS 19081
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I +ED G Y +N +G+ +TV +T+
Sbjct: 19082 IKEASKEDVGTYELCVSNSAGS--ITVPITI 19110
Score = 35.8 bits (81), Expect = 0.40
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 1782 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20924 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20980
Score = 35.8 bits (81), Expect = 0.40
Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)
Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142
+T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + +
Sbjct: 26943 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 27002
Query: 1143 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ L ++ I +D GLY N+ G + + +
Sbjct: 27003 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048
Score = 35.4 bits (80), Expect = 0.52
Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F + L ++ V+E + L C+VS P A +IW + + T + EG + I+
Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6151
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
A ED G Y C R P S +D
Sbjct: 6152 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6170
Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
VK + + I P++ ++ GE E ++ + W + K ++
Sbjct: 6171 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6220
Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
+ V L + A + G Y ++V G+ +A +LTV++K
Sbjct: 6221 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6267
Score = 35.4 bits (80), Expect = 0.52
Identities = 16/82 (19%), Positives = 37/82 (45%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
++ ++ G+ + + +G+P+P+V+W K + R + LE + D
Sbjct: 10455 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10514
Query: 229 GVYTCLVVNGSGKASMSAELSI 250
G Y +V N +G ++++
Sbjct: 10515 GKYCVVVENSTGSRKGFCQVNV 10536
Score = 35.4 bits (80), Expect = 0.52
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)
Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676
KP + L G+ L V G + + V G P PEV W + ++ S + R
Sbjct: 11828 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11885
Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+ + D G Y A N+AG A + V
Sbjct: 11886 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921
Score = 35.4 bits (80), Expect = 0.52
Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)
Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
+ +A+NA G +S + T + K E LP P + + V G
Sbjct: 17221 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17271
Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
+ V G P P + WL EI+ES + + L +++ D G Y A N
Sbjct: 17272 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17331
Query: 701 AG 702
AG
Sbjct: 17332 AG 17333
Score = 35.4 bits (80), Expect = 0.52
Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ +K G K + G P P ++W ++G I R + T L + D
Sbjct: 19427 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19485
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
G+Y N +G R V V V G ++ ++ S P + I
Sbjct: 19486 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19545
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205
K T + EG++ SCK+T LKGN + +P
Sbjct: 19546 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 19598
Query: 206 RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
V++ + V LEI V ++ + + C S S + I+ + +
Sbjct: 19599 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 19656
Query: 260 FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314
+VR K D+R + T + E ++ + AA S S R P + P
Sbjct: 19657 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 19712
Query: 315 QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373
PP + K+ +S K + A P+ + + + + S G E
Sbjct: 19713 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 19772
Query: 374 PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
A + R +G+ D S +++ +I E + + F ++ VK +
Sbjct: 19773 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19831
Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
G P P V W T +R + ++ + S L + A DSG Y+ T
Sbjct: 19832 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 19888
Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526
N S + ++V + V K+ AV+
Sbjct: 19889 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 19924
Score = 35.4 bits (80), Expect = 0.52
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V++G + R + I G+P P W K + A ++ SE + L I ++ D G
Sbjct: 23774 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23831
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y ++ N GK ++ ++ + G
Sbjct: 23832 TYDLVLENKCGKKAVYIKVRVIG 23854
Score = 35.4 bits (80), Expect = 0.52
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1816
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 26002 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26059
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
I D DD Y N GEA+ A L V
Sbjct: 26060 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091
Score = 35.0 bits (79), Expect = 0.68
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5470 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5527
Query: 1820 DVCGDDDAKYTCKA 1833
+D+AKY +A
Sbjct: 5528 SAAFEDEAKYMFEA 5541
Score = 35.0 bits (79), Expect = 0.68
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
R+VV G + R ++G+P P VTW L A + + + V I +
Sbjct: 10161 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10218
Query: 229 GVYTCLVVNGSGK 241
GVY+ L N +G+
Sbjct: 10219 GVYSLLAKNEAGE 10231
Score = 35.0 bits (79), Expect = 0.68
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
++ G + VRG P P+VTW + G + G L+D LVI +D
Sbjct: 12246 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12301
Query: 102 GKYTCEATNGSGARQVTVELTV 123
GKY+ N +G + V V + V
Sbjct: 12302 GKYSLTLVNPAGEKAVFVNVRV 12323
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12991
Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
YT A NS G + T +L V
Sbjct: 12992 GDYTITAENSSGSKSATIKLKV 13013
Score = 35.0 bits (79), Expect = 0.68
Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 615 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
VA AP + L+GL DL + + S + + + G P P V W + +
Sbjct: 13600 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13659
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721
E +L + + D G YT N AG + T ++ V +P T P
Sbjct: 13660 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13710
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
D + AP + P+I K G +V + I G+P P+ +W K +
Sbjct: 13999 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 14048
Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
+PS ++ +L I + D G YT N G
Sbjct: 14049 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14087
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
+V G ++ + I+G P P V RDG L K T F + T+ LK+
Sbjct: 20113 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20171
Query: 789 AGQYEILLKNRVGECSCQVSLML 811
AG+YEI N G +++++
Sbjct: 20172 AGRYEITAANSSGTTKAFINIVV 20194
Score = 35.0 bits (79), Expect = 0.68
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565
V+++ ++ V+K A G L+ + G P P I W + + +Q C +
Sbjct: 20499 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 20555
Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
A + I+DA + G Y NA+G S + V + +K
Sbjct: 20556 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20593
Score = 34.7 bits (78), Expect = 0.89
Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%)
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
V P+ W G PV + + E+ G Y Y A N QG
Sbjct: 7252 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 7298
Query: 497 SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553
S T +++ + E F V L V G L +V G P P+ITW
Sbjct: 7299 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7358
Query: 554 I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
+ Q R T E + + I D+ D GTY A N G+ + V V +K
Sbjct: 7359 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7411
Score = 34.7 bits (78), Expect = 0.89
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + G P P + W+ E+ + + SL +++ D+G Y +
Sbjct: 16186 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16245
Query: 697 AWNSAGE 703
A N AGE
Sbjct: 16246 AKNVAGE 16252
Score = 34.7 bits (78), Expect = 0.89
Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%)
Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451
+SK ++ P+ + + P+ P+ ++ V +T + +V G P P + W L G
Sbjct: 17232 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 17290
Query: 452 TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
+ E+ L + A D G Y ASN G S
Sbjct: 17291 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 17336
Score = 34.7 bits (78), Expect = 0.89
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ AT + ++G PEP+V W + +T + + +F+ LVI V D G
Sbjct: 18747 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18802
Query: 103 KYTCEATNGSGARQVTVELTV 123
+Y N SG++ V + V
Sbjct: 18803 RYNLTLENNSGSKTAFVNVRV 18823
Score = 34.7 bits (78), Expect = 0.89
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 19021 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19079
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I + +D Y NS G T +IV
Sbjct: 19080 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19112
Score = 34.3 bits (77), Expect = 1.2
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6274 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6331
Query: 1824 DDDAKYTCKAVNSLGE-ATCTAELIVE 1849
DD A Y N GE A LIVE
Sbjct: 6332 DDQANYNVSLTNHRGENVKSAANLIVE 6358
Score = 34.3 bits (77), Expect = 1.2
Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%)
Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470
+A PK ++ Q V + + PK E WF E P+ + +I+ + S
Sbjct: 6625 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 6681
Query: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523
+L+A+ D G Y N G+ L+ V L V E S+ +
Sbjct: 6682 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 6740
Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLL 549
+ +G ++ V + R TW+L
Sbjct: 6741 PLTDGGSKIIGYVVERRDIKRKTWVL 6766
Score = 34.3 bits (77), Expect = 1.2
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
G+ L S +K +S DPS + PLT AF+ P +L K+G +
Sbjct: 6987 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 7044
Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
GYP P TW + + +G R + + LVI D+G YT + N
Sbjct: 7045 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 7099
Score = 34.3 bits (77), Expect = 1.2
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
G + VK G R + G+P P+V W K L S RV + + + +
Sbjct: 11837 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11896
Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250
D G Y N +G A +++
Sbjct: 11897 SDGGKYVVTATNTAGSFVAYATVNV 11921
Score = 34.3 bits (77), Expect = 1.2
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 1761 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17656 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17711
Query: 1821 VCGDDDA-KYTCKAVNSLG 1838
C +DA KY K NS G
Sbjct: 17712 NCDRNDAGKYILKLENSSG 17730
Score = 34.3 bits (77), Expect = 1.2
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
P V + E P + L R + +++G + ++G P P W + GQ I+
Sbjct: 23750 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23807
Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
R ++ T LVI D G Y N G + V +++ V GS
Sbjct: 23808 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23855
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+ G + I ++G P PTV W + + L ++ + ++V+K Q H
Sbjct: 10162 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10218
Query: 790 GQYEILLKNRVGE 802
G Y +L KN GE
Sbjct: 10219 GVYSLLAKNEAGE 10231
Score = 33.9 bits (76), Expect = 1.5
Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%)
Query: 537 VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
+RG PVP W +G I ++ + + L I++ L D G Y NA G +
Sbjct: 11162 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11221
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
+ +TV + P PT PI ++D + MT +S PP +
Sbjct: 11222 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 11258
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15162
Query: 1832 KAVNSLGEA 1840
A N G A
Sbjct: 15163 TATNPGGFA 15171
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)
Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
+P+ V P E +LPP + + I+ T + ++G P P+V W R+
Sbjct: 15469 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15526
Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
G L I T S L++ V+ D GKY N SG++ V + V
Sbjct: 15527 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15576
Score = 33.9 bits (76), Expect = 1.5
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + G + + V + G P PEV W EI+++ T SL + V D+G
Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16637
Query: 692 TYTCEAWNSAG 702
YT NS+G
Sbjct: 16638 KYTLTLENSSG 16648
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
+++ P V + +T E +P + ++ G E +G P+P ++W ++G P+
Sbjct: 21175 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21234
Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
F+ +L I +E GKYT N ++ V +TV
Sbjct: 21235 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21279
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 1745 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1794
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 23056 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23110
Query: 1795 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 23111 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23157
Score = 33.5 bits (75), Expect = 2.0
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5204 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5261
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+V DD ++ + + E + TA+L V
Sbjct: 5262 EVTLDDISQIKAQ----VKELSSTAQLKV 5286
Score = 33.5 bits (75), Expect = 2.0
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5559 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5616
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCT 1843
D+ DD ++ +A+ EA T
Sbjct: 5617 DLSIDDTSQIRVEAMGMSSEAKLT 5640
Score = 33.5 bits (75), Expect = 2.0
Identities = 20/72 (27%), Positives = 32/72 (44%)
Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
TG P+P TW G+ L+ RV + + L I + D G+YT + N S
Sbjct: 7047 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7106
Query: 245 SAELSIQGLDSA 256
++++ SA
Sbjct: 7107 EIDVNVIARPSA 7118
Score = 33.5 bits (75), Expect = 2.0
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)
Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
S IS+ ++ DP P L ++ + EG R P P V+WH++
Sbjct: 8000 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 8051
Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
G+ + + R + V +V D G YT N G+ ++ + V G
Sbjct: 8052 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 8106
Score = 33.5 bits (75), Expect = 2.0
Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582
G L+ VRG P P + W + RS A ++ + A D G Y
Sbjct: 11844 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11903
Query: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
A N G A V V +K ++ ++ V+ + T
Sbjct: 11904 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 11942
Score = 33.5 bits (75), Expect = 2.0
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
+ L ++ G T + V+G P P++TW + + R LD I+ T F + V
Sbjct: 13329 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13384
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
++ D GKY N G ++ T+ + V
Sbjct: 13385 NKYDAGKYILTLENSCGKKEYTIVVKV 13411
Score = 33.5 bits (75), Expect = 2.0
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
VK V S S S DP E P F + + L +K GA+ RG P
Sbjct: 19785 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19842
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P V W + + + R +D T SL I + D GKYT N A +T+
Sbjct: 19843 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19899
Query: 121 LTV 123
+ V
Sbjct: 19900 VKV 19902
Score = 33.5 bits (75), Expect = 2.0
Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572
S + K V G F + RG PVP + W +P R+ + L I++
Sbjct: 19818 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19874
Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTV 600
A D G YT +N L S + V V
Sbjct: 19875 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19902
Score = 33.5 bits (75), Expect = 2.0
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G
Sbjct: 19824 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19881
Query: 692 TYTCEAWN 699
YT N
Sbjct: 19882 KYTLTIQN 19889
Score = 33.1 bits (74), Expect = 2.6
Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G KL+ + +LSV+ ++ I R+L E FE + +
Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W+ + I ++ ++ + + L + + ++D GKYT A G + +L
Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
TV G +SK L D+ V E Q F
Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C++ P + WL+ L + + + L I DD+G YT V
Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653
Query: 242 ASMSAE 247
A + E
Sbjct: 2654 AKLKVE 2659
Score = 33.1 bits (74), Expect = 2.6
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 1725 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1770
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 5244 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5303
Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 5304 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5360
Query: 1831 CKAVNSLGEATCTAE 1845
C +A T E
Sbjct: 5361 CDCGTDKTKANVTVE 5375
Score = 33.1 bits (74), Expect = 2.6
Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%)
Query: 442 KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501
K EV W L V Q ++ + H L + + RD G Y A + + +
Sbjct: 6567 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 6623
Query: 502 LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561
+ AP + +D V G+ + P W +P+
Sbjct: 6624 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 6675
Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQ 591
A I +A D G Y + +N G+
Sbjct: 6676 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6705
Score = 33.1 bits (74), Expect = 2.6
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160
+ V G+ + + V+ P I W+ N + K T + +++E + +SI KA
Sbjct: 9036 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 9095
Query: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
+ ED+G Y A N G + V V D P+
Sbjct: 9096 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9127
Score = 33.1 bits (74), Expect = 2.6
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10854 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10910
Query: 1825 DDAKYTCKAVNSLGEATCTAELIV 1848
D Y+ N G T + +++V
Sbjct: 10911 DGGIYSLTVENPAGSKTVSVKVLV 10934
Score = 33.1 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575
+D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D +
Sbjct: 19424 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19482
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
D G Y +N G S + V +K P P P+ + GL+
Sbjct: 19483 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19524
Score = 33.1 bits (74), Expect = 2.6
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ GA+ + +G P P W + ++ D +FS L + + D G
Sbjct: 21997 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 22052
Query: 103 KYTCEATNGSGARQVTVELTV 123
KYT N SG++ +T + V
Sbjct: 22053 KYTLTVENNSGSKSITFTVKV 22073
Score = 32.7 bits (73), Expect = 3.4
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 1824 DDDAKYTCKAVNSLGEAT 1841
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 3.4
Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163
G ++ + + P W +GK K K + L + + I +
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9512
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
G Y AKN AGQ +C+V V D P
Sbjct: 9513 HTGKYSITAKNKAGQKTANCRVKVMDVP 9540
Score = 32.7 bits (73), Expect = 3.4
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1830
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22690 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22747
Query: 1831 CKAVNSLG 1838
N+ G
Sbjct: 22748 LTVKNASG 22755
Score = 32.3 bits (72), Expect = 4.4
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 1765 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6187 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6242
Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
D Y V +G A A L V
Sbjct: 6243 LQDMGTY----VVMVGAARAAAHLTV 6264
Score = 32.3 bits (72), Expect = 4.4
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 614 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
P+ AP + L L + G +T + SG P P+V W + ++ E + H
Sbjct: 10436 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10495
Query: 672 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702
+ T +L ++++ + D+G Y NS G
Sbjct: 10496 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10526
Score = 32.3 bits (72), Expect = 4.4
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575
KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+
Sbjct: 15096 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15154
Query: 576 EDHGTYTCLAENALG 590
D G YT A N G
Sbjct: 15155 RDSGAYTLTATNPGG 15169
Score = 32.3 bits (72), Expect = 4.4
Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584
G + + + G P+P++T +G P++ AE +++++++ D G Y
Sbjct: 20119 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20178
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635
A N+ G + V ++ P PT P+ + +++ V
Sbjct: 20179 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20225
Query: 636 DGSQVT 641
GSQVT
Sbjct: 20226 GGSQVT 20231
Score = 32.3 bits (72), Expect = 4.4
Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
P + L+ +K G+ V + +SG P P + W + E+Q + E S
Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20557
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
+ I++ ++G Y + N+ G A + VQ
Sbjct: 20558 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20589
Score = 32.3 bits (72), Expect = 4.4
Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
+P + + + G + + G P P +W G + R ++ + L I
Sbjct: 23371 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23429
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
D G+YT E N +G T+++ +
Sbjct: 23430 TIRDTGEYTLELKNVTGTTSETIKVII 23456
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 1760 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187
Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ D Y+C V T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)
Query: 1694 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1746
W K G V+ I + S M +I ++ K G+ + + A L + VS +
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
+ + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 1763 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1819
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12239 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12294
Query: 1820 DVCGDDDAKYTCKAVNSLGE 1839
+ DD KY+ VN GE
Sbjct: 12295 NSTRDDSGKYSLTLVNPAGE 12314
Score = 32.0 bits (71), Expect = 5.8
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786
R++ G S+ I I G P P V W +D L K+ + E N + FT L++ +
Sbjct: 14412 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14467
Query: 787 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819
+ G++ + ++N G+ S V++ + ++ L
Sbjct: 14468 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14500
Score = 32.0 bits (71), Expect = 5.8
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18401
Query: 1824 DDDAKYTCKAVN 1835
D +Y K N
Sbjct: 18402 TDGGQYILKLSN 18413
Score = 32.0 bits (71), Expect = 5.8
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
K G+ + + G P P+VTW + R + + +L + D G+Y
Sbjct: 22288 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22346
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
N +G + +V + V G G VS + E+ WGE
Sbjct: 22347 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22398
Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+
Sbjct: 22399 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22451
Score = 31.6 bits (70), Expect = 7.6
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13624 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13682
Query: 1831 CKAVNSLG--EATCTAELI 1847
N G E T + +++
Sbjct: 13683 ITLKNVAGTKEGTISIKVV 13701
Score = 31.6 bits (70), Expect = 7.6
Identities = 19/80 (23%), Positives = 30/80 (37%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V +T ++ G P P+V W +G + +E+ L + D G
Sbjct: 18347 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406
Query: 485 YSCTASNAQGQLSCSWTLQV 504
Y SN G S T++V
Sbjct: 18407 YILKLSNVGGTKSIPITVKV 18426
Score = 31.6 bits (70), Expect = 7.6
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694
G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y
Sbjct: 18350 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18408
Query: 695 CEAWNSAG 702
+ N G
Sbjct: 18409 LKLSNVGG 18416
Score = 31.2 bits (69), Expect = 9.9
Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 1733 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 1779
E L+ E+ ++ E+ EE VK P + D EG
Sbjct: 4330 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4389
Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 1838
I EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G
Sbjct: 4390 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4446
Query: 1839 EATCTAELIV 1848
+ +A+L V
Sbjct: 4447 KTATSAKLTV 4456
Score = 31.2 bits (69), Expect = 9.9
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 1076 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1135
NC+ + T K E A F K Q++ + EG+K C +S + + W +
Sbjct: 6161 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 6216
Query: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
KTL++ + +G + ++ A +D G Y + G A + +TV
Sbjct: 6217 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 6264
Score = 31.2 bits (69), Expect = 9.9
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14412 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14468
Query: 1825 DDAKYTCKAVNSLGE 1839
D K+ N G+
Sbjct: 14469 DTGKFVMTIENPAGK 14483
Score = 31.2 bits (69), Expect = 9.9
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 685
L V G + + V + G P PEV W L N I+ +E F L I E
Sbjct: 14414 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 14465
Query: 686 FPEDTGTYTCEAWNSAGE 703
DTG + N AG+
Sbjct: 14466 NRYDTGKFVMTIENPAGK 14483
Score = 31.2 bits (69), Expect = 9.9
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1830
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14765
Query: 1831 CKAVNSLGE 1839
A N +GE
Sbjct: 14766 LTARNIVGE 14774
Score = 31.2 bits (69), Expect = 9.9
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
+V G++ + ++G P PT+ W +DGK L + T E+ + LV K
Sbjct: 15098 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 15156
Query: 789 AGQYEILLKNRVG 801
+G Y + N G
Sbjct: 15157 SGAYTLTATNPGG 15169
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19424 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19482
Query: 1824 DDDAKYTCKAVNSLG 1838
D +Y N G
Sbjct: 19483 RDTGQYVLTLKNVAG 19497
Score = 31.2 bits (69), Expect = 9.9
Identities = 19/71 (26%), Positives = 30/71 (42%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V V+ G + I+G+P P+VT + VPL+ + R + + + D G
Sbjct: 20114 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20173
Query: 230 VYTCLVVNGSG 240
Y N SG
Sbjct: 20174 RYEITAANSSG 20184
Score = 31.2 bits (69), Expect = 9.9
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1830
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 22000 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 22055
Query: 1831 CKAVNSLGEATCT 1843
N+ G + T
Sbjct: 22056 LTVENNSGSKSIT 22068
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 583
V +G L ++G P P W GQ I + A EL I++A D GTY
Sbjct: 23776 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 23835
Query: 584 LAENALGQ 591
+ EN G+
Sbjct: 23836 VLENKCGK 23843
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 295 bits (755), Expect = 3e-79
Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154
AP FK++L++++V L C+V+ P + W GK + K+ I +G
Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
+ I +D +Y+ A N G + + V+
Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24523
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
P K +P + +R GE V + +G TW K
Sbjct: 24524 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24567
Query: 1275 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
+ I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP
Sbjct: 24568 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24627
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393
P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V +
Sbjct: 24628 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24686
Query: 1394 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453
L Y+FRV A N +G S+PS+ SE T E + E D+ EV +
Sbjct: 24687 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24743
Query: 1454 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513
++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+
Sbjct: 24744 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24802
Query: 1514 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573
N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E +
Sbjct: 24803 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 24862
Query: 1574 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633
+++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV
Sbjct: 24863 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 24922
Query: 1634 NYEPIGYATDMWSIGVICYIL--------------------------------------- 1654
++ + ATDMWS+G + Y+L
Sbjct: 24923 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 24982
Query: 1655 ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1702
+R+ ++ LQHPWL + + + K + + ++Y +K N V
Sbjct: 24983 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25041
Query: 1703 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1762
+ R+S I +S G + + +E VS + AV EE HVK
Sbjct: 25042 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25089
Query: 1763 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
+ CKIE Y +V W+ + + S ++I Y EDG L + D+
Sbjct: 25090 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25134
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
DD Y CK VN GE + AEL V+ + E
Sbjct: 25135 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25166
Score = 164 bits (416), Expect = 6e-40
Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%)
Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
+VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++
Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26310
Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
+ S K+ Q T+ + A E S P T L
Sbjct: 26311 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26365
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y
Sbjct: 26366 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26425
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285
TC V N +G S S +L+I+ + V K + + V++E++ + ++
Sbjct: 26426 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 26485
Query: 286 DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
EA ++ SK S + S + +K + RT +
Sbjct: 26486 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 26545
Query: 337 VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388
T SI + R+ + G GV + EE + T +Q
Sbjct: 26546 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26603
Query: 389 LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
+ + +SK + + + S P F S+P+SQ + E Q V F CE+SG
Sbjct: 26604 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 26663
Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
P PE+ WF P+ ++ + + L + A DSG Y+ A N +GQ CS
Sbjct: 26664 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 26720
Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560
T + L ++E PS VL+ D LQ S + Q +Q + S
Sbjct: 26721 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 26762
Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613
EA + A + ++ ++ ++S S+++ + S +
Sbjct: 26763 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 26822
Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671
A + P SD+ + +G +T+ +G P PEV W G +I QE FH
Sbjct: 26823 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 26882
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
E +L I +V +D G YT N G
Sbjct: 26883 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 26913
Score = 155 bits (391), Expect = 5e-37
Identities = 124/475 (26%), Positives = 201/475 (42%), Gaps = 79/475 (16%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P+ + Q V+ + +F +SG P+P+++W+ E + + D + L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3251
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526
L++A D+ Y+C A N G + S +L VE V+ P+ + L+D
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311
Query: 527 EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583
EGQ QC V GT + +++W + P ++ R T +L I +A PED GTYT
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370
Query: 584 LAENALGQVSCSAWVTVHEKKS------------------------------------SR 607
+A NA+GQVS +A +++ +S S+
Sbjct: 3371 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 3430
Query: 608 KSEYL-----LPVAPSK------PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
+E L PV P+K T PIF++ +S+ + G T++V V G P P++ W
Sbjct: 3431 INETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQW 3490
Query: 657 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ--- 713
NG + S D+ F G HSL I ED G YTC A N G+ A L +
Sbjct: 3491 FFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG 3550
Query: 714 EPHDGTQ-----------------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
E H T+ P F+ + + + + G + + G+P PTV W +
Sbjct: 3551 EGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFK 3610
Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
+ K LC + + T ++ Q +G Y +N +GE +C L++
Sbjct: 3611 ENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 134 bits (336), Expect = 1e-30
Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%)
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
S + P + S+ P + Q V + KF + +G P+P W +G +
Sbjct: 26337 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 26396
Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
Q G ++ ED G +L + K T DSG Y+CT N+ G +S S L ++
Sbjct: 26397 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 26445
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+KD E Q Q + TP + ++ + Q A + E ++E Q+ L
Sbjct: 26446 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 26497
Query: 576 -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631
++ + ++E + S + VHE+ K+S+ SE + A K + +
Sbjct: 26498 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 26550
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + +G ++ + ++G +V W+ NG E+ SE++ + G+ +L I++ D G
Sbjct: 26551 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26608
Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
TC + G V+ Q LT+ + P FIS+PRS + GQ+VL +C I+G+P P
Sbjct: 26609 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26667
Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
+ W ++ + + + + ++ +V++L ++ +G+Y I KN G+CS SLM+
Sbjct: 26668 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726
Query: 812 QNSSARALPRGREPA 826
LP EP+
Sbjct: 26727 -------LPLVEEPS 26734
Score = 122 bits (306), Expect = 3e-27
Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++
Sbjct: 23654 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23710
Query: 795 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848
+L+N+ G+ + + + + S P G P +D+ V AD GG+D G
Sbjct: 23711 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23766
Query: 849 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906
+ W + VRG +++ E R Q L + V+
Sbjct: 23767 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 23824
Query: 907 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963
KT L+ + P E +D + + + +V + ++ + K +
Sbjct: 23825 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 23883
Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022
KT + + PD + ++ A+N +ET A + V P G
Sbjct: 23884 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 23939
Query: 1023 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070
L+ + +K + TL KP K D K ++KE +K
Sbjct: 23940 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 23999
Query: 1071 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
+N+ R T + K + G AP +++++DV G+ L CQ
Sbjct: 24000 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24058
Query: 1121 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180
+ P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E
Sbjct: 24059 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24118
Query: 1181 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
S ++ + P P P K
Sbjct: 24119 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24138
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299
E G ++ L G TW +K +Q SE++ +EN+E+ + L +
Sbjct: 24139 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24194
Query: 1300 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG
Sbjct: 24195 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24254
Query: 1360 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P +
Sbjct: 24255 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24314
Query: 1418 ESELTTVGEKPEEP 1431
S + + E+P
Sbjct: 24315 VSSVVIIKSPFEKP 24328
Score = 118 bits (295), Expect = 6e-26
Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)
Query: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680
T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 681 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714
I+E F ED+G +TC A N AG V T L VQ
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 715 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
P + P+FI+KP G SV+ C + G+P P V+W + G
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 760 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ +
Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131
Query: 817 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875
L + ++ + V + G PG+ + + E+E + + K
Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186
Query: 876 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932
V R + E+ QE F + L K++ KT E+ L+E E+M +
Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242
Query: 933 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981
V+ S + ++ + + ++ V S P+P +++ + DF
Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298
Query: 982 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035
R+ L LP + G +A N K NA SG P P+G TL
Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350
Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095
+P+ + +L P ++ + A + + + S+ +
Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407
Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152
P F K EG+ +V P W +G+ + T +++ ++G+
Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467
Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212
S+ I A P D G + VA+N AG++ S +TV+
Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504
Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
+ + P ++ ++ ++ G +E+ + TG W+
Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544
Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327
K I ++ +++E ++ + L I + + YT NK G + + +VN+ V
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604
Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348
+P+P P GT A +I + L
Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631
Score = 115 bits (288), Expect = 4e-25
Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483
+ E Q + + ++G +V W L G + E Y +GS +K A RD G
Sbjct: 26553 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 26608
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
+C + +G + C + L + + + AP+F S + + EGQ+ + C + G P P
Sbjct: 26609 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26666
Query: 544 RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
I W N PI + + V L I++A D G YT A+N GQ S +A + V
Sbjct: 26667 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
LP+ +P+ + L+ D + GS + +VQ+S + +
Sbjct: 26727 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 26772
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
+ + F Q +QE F E + + N ++ + ++ G
Sbjct: 26773 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 26831
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779
P + P ++ G+ + ++CA G+P P V W G+ + ++ G F + +D+ TL
Sbjct: 26832 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 26891
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813
++ VQ G Y + L N G S V++ +++
Sbjct: 26892 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 26925
Score = 115 bits (287), Expect = 5e-25
Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
F +++ + EG F CK++G P P++ W K R+ E+ M L+
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1297
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282
G+AS+ + + + +F K N I
Sbjct: 1298 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1330
Query: 283 SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342
KL +E AA G+P + +P S++ S SPR+ ++P+
Sbjct: 1331 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1369
Query: 343 SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402
R+ P +P R PA PA PG ++ R
Sbjct: 1370 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1408
Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
P F KP S + E QT +F +V G P PE WF +G +
Sbjct: 1409 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1459
Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
V ++ G+ L ++ A DSG ++ A N G+ S S L VE + +V P F LK+
Sbjct: 1460 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1518
Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577
+ EG ++ G P P I WL N P +Y + E G A L I + +D
Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578
Query: 578 HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617
YT A N G+ C V V + + + ++P AP
Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1638
Query: 618 -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662
K P F + L+ L++ +++ G+P V WLH+G
Sbjct: 1639 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714
++ + SL + D+G TC A N G T A L V++
Sbjct: 1699 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1758
Query: 715 ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744
H+G +P + P V G++ C +
Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1818
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G
Sbjct: 1819 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1876
Query: 805 CQVSLMLQNSS--ARALPRGREP 825
+V L +Q L R EP
Sbjct: 1877 HKVKLEIQQREDFRSVLRRAPEP 1899
Score = 113 bits (282), Expect = 2e-24
Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
+K S RK E L + AP + +V G + V P EV W HNG
Sbjct: 25856 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 25915
Query: 662 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682
E+QES D H + GT ++C
Sbjct: 25916 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 25975
Query: 683 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718
+ VFPE T T EA +S EV++Q T + H
Sbjct: 25976 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26035
Query: 719 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752
+ ++KPRS+T G+S SC G+P PTV
Sbjct: 26036 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26095
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q
Sbjct: 26096 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154
Query: 813 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848
+ + ++ R + P +++
Sbjct: 26155 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26214
Query: 849 LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
L P + +L+ E +++ VL+ + T + +++ Q +
Sbjct: 26215 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26274
Query: 901 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954
++ L+E D + EI E + NLQ + K++ E+ K+ ++ D +
Sbjct: 26275 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26334
Query: 955 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983
S + +K K P P P P+P T D ++
Sbjct: 26335 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26394
Query: 984 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015
+ GGK KL + G SS+ L KA++ ++
Sbjct: 26395 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26454
Query: 1016 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067
+ Q + + P A E + A +E +K M AK E L + ASK EE+
Sbjct: 26455 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26511
Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
KK + H T + SE T K + + EG++L+L+ ++
Sbjct: 26512 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26569
Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ W LNG L ++ GS +++I++A D G+ C++K G +C +T+
Sbjct: 26570 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26629
Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247
+ E+ SDA P I P Q
Sbjct: 26630 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26646
Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
+ G++V +++G W K I S ++ + S N L I A G
Sbjct: 26647 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26706
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S
Sbjct: 26707 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26766
Query: 1368 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423
+ S++ + + + S + Q + E + + + G S +Q S++
Sbjct: 26767 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 26824
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEV 1447
G + PK E SD E +V
Sbjct: 26825 AGIRGIPPKIEALPSDISIDEGKV 26848
Score = 112 bits (279), Expect = 4e-24
Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
+N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E
Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
D G YT A+N G + +L VE A LG P TL R +P +R I
Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369
Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
P F K EGQ R
Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429
Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
F K+ GRP P+ W G + V +++G Q L I D G +T + N
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489
Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
+G++S+S L+++ ++ FV + K N I + S+L+ A + N
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538
Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
W NS P + ++E K + V Q
Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592
Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
T + ++ +PEP ++ P G R K A P P Q D+
Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453
K ++ P F+ K S +K F C ++ G P V W +G P
Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698
Query: 454 VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502
+ + + + G L A +RDSG +C A+N G S TL
Sbjct: 1699 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757
Query: 503 -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536
++E L M + + V D V+EG+ +C
Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817
Query: 537 VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594
V G P P++ W LNGQ I+ ++ G+ L I D D G AEN G +
Sbjct: 1818 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1877
Query: 595 SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
+ + +++ R +L AP +P + G +V + T + E
Sbjct: 1878 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1929
Query: 654 VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694
V+ L I +ESE+ F++R + S E + E
Sbjct: 1930 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 1989
Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738
E + E+ + + E T P F + +S T G
Sbjct: 1990 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2049
Query: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
+ G P P W ++G + + + ++V LV++ V + + N
Sbjct: 2050 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2109
Query: 799 RVGECSCQVSLMLQ 812
GE S L++Q
Sbjct: 2110 IAGETSSHAFLLVQ 2123
Score = 111 bits (278), Expect = 6e-24
Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
+PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L
Sbjct: 12401 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12459
Query: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355
I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+
Sbjct: 12460 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12519
Query: 1356 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE
Sbjct: 12520 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12579
Query: 1415 PSQESELTTVGE--KPEEPKD 1433
P ++ P EPK+
Sbjct: 12580 PLTSPKMVAQFPFGVPSEPKN 12600
Score = 110 bits (275), Expect = 1e-23
Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567
AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I + G Y+ A N GQ + +A + V K+E AP P F+Q
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168
Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713
ED+GTY+ A NS G + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 109 bits (272), Expect = 3e-23
Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)
Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58
Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
S L I AV + + G+Y+ +ATNGSG T EL V+ A
Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PP F +L + V++G R ++TG P P V + + +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
+S++ + L I +D G Y+ N G+A+ +AEL +QG
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ +A S R+T+ + + ++ + E +D AA + +P R PP +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263
Query: 312 SQPQPP 317
P PP
Sbjct: 264 RSPTPP 269
Score = 109 bits (272), Expect = 3e-23
Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7264
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y +
Sbjct: 7265 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7323
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426
E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T +
Sbjct: 7324 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7383
Query: 1427 KPEEPKDEVEVSD 1439
P P +E SD
Sbjct: 7384 DPPGPPTRLEPSD 7396
Score = 105 bits (262), Expect = 4e-22
Identities = 101/411 (24%), Positives = 157/411 (38%), Gaps = 48/411 (11%)
Query: 415 KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
+F + +V E + F CEVS P V W + ++ + I++ ++ H L +
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3070
Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
R D+G Y+ A + +L V S+ K+ VIE Q V++
Sbjct: 3071 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3121
Query: 535 CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
V V W +G I + + E + + I + D G YT +A
Sbjct: 3122 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3178
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
+R S L AP P LQ L + V G +SG
Sbjct: 3179 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3219
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
P P++ W + F G +++L + E FPED YTCEA N G T A
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279
Query: 710 LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
L+V+ P D P + I+ + S GQ C ++G + +D K
Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3337
Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
K + F + Q ED + L + + P G Y + N VG+ S +L L+
Sbjct: 3338 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3388
Score = 104 bits (260), Expect = 7e-22
Identities = 104/484 (21%), Positives = 179/484 (36%), Gaps = 53/484 (10%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP+ +L V V+ G+ RF I+GRPQP+++W K L + L
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
+ +D VYTC N G A+ SA LS++ V E + + ++ +I
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVSPDQEMPVYPPAII 3302
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQP-QPPRESKLESCKDSPRTAPQTPVL 338
+ + E C W + + +P R ++ +D+ +
Sbjct: 3303 TPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYP 3362
Query: 339 QKTSSSITLQAARVQPEPRAPGLGVLSPSG-------EERKRPAPPRPATF-PTRQPGLG 390
+ + + + V L + +P +E + ++F + GL
Sbjct: 3363 EDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLH 3422
Query: 391 SQDVVSKAANRRIPM-----------EGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSG 439
S ++ N + + + +++ P F + + ++ V G
Sbjct: 3423 SAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIG 3482
Query: 440 IPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCS 499
IPKP++ WF G + V+ D H L +L + D G Y+C ASN G+ CS
Sbjct: 3483 IPKPKIQWFFNGVLLTPSADYKFVF-DGDDHSLIILFTKLEDEGEYTCMASNDYGKTICS 3541
Query: 500 WTLQVE-----------RLAVME--------VAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
L++ AV + P F LK +G + + +V G
Sbjct: 3542 AYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGE 3601
Query: 541 PVPRITWLLNGQ----PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
P P +TW + + Y G + D ED G Y C AEN LG+ +C+A
Sbjct: 3602 PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAA 3661
Query: 597 WVTV 600
+ V
Sbjct: 3662 ELLV 3665
Score = 102 bits (253), Expect = 5e-21
Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
+++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A
Sbjct: 20379 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20438
Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
+ + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG
Sbjct: 20439 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20498
Query: 1361 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
+ + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP
Sbjct: 20499 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20555
Query: 1417 QESEL 1421
+ +
Sbjct: 20556 ESDSV 20560
Score = 101 bits (252), Expect = 6e-21
Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)
Query: 1236 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
+PP + ++ E V+AG +V + G T W +I+ EH VE
Sbjct: 11009 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11068
Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352
S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW
Sbjct: 11069 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11128
Query: 1353 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411
DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G
Sbjct: 11129 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11188
Query: 1412 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469
P +S T K P P + V+D E V + + ++ +Y +E R
Sbjct: 11189 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11246
Query: 1470 LGSGKFGQV 1478
+GK+ +V
Sbjct: 11247 EVTGKWVRV 11255
Score = 101 bits (252), Expect = 6e-21
Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++
Sbjct: 16043 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16099
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL
Sbjct: 16100 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16159
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N
Sbjct: 16160 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16219
Query: 1410 YGTSEPSQESELTTVGE--KPEEPK 1432
YG EP + + P+ PK
Sbjct: 16220 YGVGEPLESEPVVAKNPFVVPDAPK 16244
Score = 101 bits (251), Expect = 8e-21
Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)
Query: 1243 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302
F + VRAG S+ LF G T W K + S + +++ S LT+ +
Sbjct: 21866 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 21923
Query: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362
G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+
Sbjct: 21924 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 21982
Query: 1363 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421
+ Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E
Sbjct: 21983 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22042
Query: 1422 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471
E+P P+ D V+ S +P+ D + QK SDF+ +E
Sbjct: 22043 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22101
Query: 1472 SGKFGQVFRLVEK 1484
V RLVEK
Sbjct: 22102 KQLTFTVERLVEK 22114
Score = 100 bits (250), Expect = 1e-20
Identities = 133/588 (22%), Positives = 220/588 (37%), Gaps = 101/588 (17%)
Query: 63 QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119
+V W+ + + S +F L D + T++LVI V+ ED +G+Y CEA N SG +
Sbjct: 4271 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4327
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
+LTV A PV+ + K+ + V G + +
Sbjct: 4328 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4355
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F+C+I P + W K + S + S+ + LEI D G YTC N
Sbjct: 4356 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4415
Query: 240 GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294
G S +A L ++ G + R + E K + ++EV +V+ K + + + K
Sbjct: 4416 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4472
Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
+ P PP P+P E ++ + R P+ + + +I L A +P
Sbjct: 4473 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4526
Query: 355 EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414
+P A + P E P P T P ++ +AA + P++G
Sbjct: 4527 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4585
Query: 415 KFES-----KPQSQEVKENQTVKFRCEVSGIP---------------------------- 441
E+ +P S K F ++ +P
Sbjct: 4586 PIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLV 4645
Query: 442 KPEVA---WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
P A W +G+ + R+ D L ++ + D+G Y+C + +
Sbjct: 4646 SPSTAITTWMKDGSNI-RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTS 4704
Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
+ L VE L V V ++ ++ V++GQ L C + + W +G+ +
Sbjct: 4705 TAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKP 4758
Query: 559 STCEAGV----AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
GV L I DA D GTYT ENA + CS+ V V E
Sbjct: 4759 GRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKVVE 4805
Score = 100 bits (250), Expect = 1e-20
Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)
Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L +
Sbjct: 14968 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15027
Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
+ G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG
Sbjct: 15028 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15087
Query: 1361 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
+ + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP +
Sbjct: 15088 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15147
Query: 1420 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471
+ V P+ PK+ EV D P+ D + IN Y +E R
Sbjct: 15148 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15197
Query: 1472 SGKFGQVFRLVEKKT 1486
K GQ + KKT
Sbjct: 15198 -DKAGQRWIKCNKKT 15211
Score = 100 bits (249), Expect = 1e-20
Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y
Sbjct: 15662 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15721
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y +
Sbjct: 15722 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15781
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
E D++ TW+ + AT T+ L EY+FR+ A N YG S
Sbjct: 15782 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 15827
Score = 100 bits (248), Expect = 2e-20
Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)
Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567
V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A
Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623
L I LPED G YT A N G CS + V Y L PV+ + +P
Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362
Query: 624 -------------------------------------------------IFLQGLSDLKV 634
+F+ K
Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481
Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
+T A N AG +LTV+ +P F+ K ++V G + + G+P P +
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541
Query: 753 HWLRD 757
WL++
Sbjct: 1542 VWLKN 1546
Score = 100 bits (248), Expect = 2e-20
Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A++ S +L +V +PL FI P ++ + E AKFE V P+
Sbjct: 5321 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5371
Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
W + Q IT RF L+ G + + + A +E + + E + SG
Sbjct: 5372 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5430
Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
+ VT + F +L + KT F
Sbjct: 5431 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5490
Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
+++ I E P F KL E C+I+ P
Sbjct: 5491 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5550
Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248
V W K ++PS + ++L + + D+G YTC G+ K S ++
Sbjct: 5551 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 5607
Query: 249 ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287
S++ +++ F ET+ + D+ + I +E K+ S
Sbjct: 5608 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 5665
Query: 288 LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341
L NC Q GG AAN + K L KD TA +T
Sbjct: 5666 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 5721
Query: 342 SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395
S L+ +++P + + P E + R + G +
Sbjct: 5722 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 5771
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
+K + + +F + Q V+E T CEVS +V WF GT +
Sbjct: 5772 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 5828
Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
+ + E+ D L + D TY+C A + + SC+ L V+
Sbjct: 5829 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 5878
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572
F L D V E + +C + ++ W +G I+ + + V L I
Sbjct: 5879 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 5937
Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632
L +D Y+C A S +TV E+++ +F + L+++
Sbjct: 5938 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 5975
Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
+V + + + +VS P EVIW EI E+ + G + L IQ ED G
Sbjct: 5976 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6034
Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
Y C +S RT + V E FISKP+++ G+ C+I+ + FP V
Sbjct: 6035 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 6085
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796
W RD K L + ++V+ + LV+K G Y +++
Sbjct: 6086 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 6128
Score = 100 bits (248), Expect = 2e-20
Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288
MPP I E +V G +V + K+ G T TW K ++ + H+
Sbjct: 9619 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9677
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348
++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + +
Sbjct: 9678 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9737
Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407
TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A
Sbjct: 9738 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9797
Query: 1408 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
N YG EP + +PE ++ V + D V ++T+N E+ D
Sbjct: 9798 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 9846
Score = 99.8 bits (247), Expect = 2e-20
Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%)
Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343
E + +K PQR S P +P P E+ +++ ++KT+
Sbjct: 693 ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 750
Query: 344 SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403
T + V PR SP K P G + ++ +A +
Sbjct: 751 LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 796
Query: 404 PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463
E S+ K ++ VK ++T R P P+ F + + E +EV
Sbjct: 797 QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 852
Query: 464 YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523
++ G + + R+ A+ + VE + P+ S LK+
Sbjct: 853 KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 906
Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580
VIEG+ L+C + G P P +TW I+ + + T ++G+A L I++A ED G
Sbjct: 907 TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 966
Query: 581 YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614
+TC A N G VS S ++ V EK+++ +E
Sbjct: 967 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1026
Query: 615 -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671
P +P AP F+ K+++G V QV GNP P V W +G + + +
Sbjct: 1027 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1086
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
++ + L I F +D G YT N GE A L + ++
Sbjct: 1087 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132
Score = 99.4 bits (246), Expect = 3e-20
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++
Sbjct: 17126 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17182
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351
+ L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+
Sbjct: 17183 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17242
Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410
W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y
Sbjct: 17243 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17302
Query: 1411 GTSEPSQES 1419
G EP + +
Sbjct: 17303 GVGEPLESA 17311
Score = 97.8 bits (242), Expect = 9e-20
Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%)
Query: 426 KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+E VK+ C++ + +V W+ + E YED G L + D GT
Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 25141
Query: 485 YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522
Y C N G+ S C T++ + + ++E P F+ L +
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 25201
Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576
G++ ++ P P +TW +GQ I+ + + G+ +L I +
Sbjct: 25202 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25261
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
D YT +A N G+ SC A +TV L P P+F + L++ + +
Sbjct: 25262 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 25311
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695
G V ++VSG PPP + W +G + + G ++L I++ PEDTG Y
Sbjct: 25312 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25371
Query: 696 EAWNSAGEVRTQAVLTVQ 713
A N+AG QA L V+
Sbjct: 25372 TATNTAGSTSCQAHLQVE 25389
Score = 97.4 bits (241), Expect = 1e-19
Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y
Sbjct: 21078 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21137
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T++++N + + + + P P G +I++ S+ LSW +GG + YSI
Sbjct: 21138 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21197
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 21198 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21245
Score = 97.4 bits (241), Expect = 1e-19
Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 25936
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278
+ DD G Y + N G+AS A L + G D + R + V E+T
Sbjct: 25937 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 25996
Query: 279 --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
+S K +EA++ + S + + S + ++++S ++ +
Sbjct: 25997 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 26053
Query: 337 VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396
+K +++ AAR+ +PR+ + GE + PT L V+S
Sbjct: 26054 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 26105
Query: 397 KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450
+A ++ + + + S S E V EN K E + I K V
Sbjct: 26106 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 26163
Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509
+P R + V +K+ R S S + + + + T +V+ L V
Sbjct: 26164 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26217
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563
P + LK A + L C V + + +TW +G+ ++ +
Sbjct: 26218 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26274
Query: 564 GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609
G EL I + D G Y C G Q A+ ++HEK KS +K+
Sbjct: 26275 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26334
Query: 610 EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
++P AP + + GL D V S V+ +G P P IW +G
Sbjct: 26335 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26394
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
I + + + L I + D+G YTC NSAG V + LT++ D
Sbjct: 26395 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26449
Score = 96.7 bits (239), Expect = 2e-19
Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y +
Sbjct: 12870 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 12928
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
+ +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P
Sbjct: 12929 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 12976
Score = 96.7 bits (239), Expect = 2e-19
Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%)
Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
K + I+KTS + + R + E AF + I EG + + G + V
Sbjct: 26521 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26571
Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
W NG +T+ + G+ G+ +L I D G TC + G + +LT+
Sbjct: 26572 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26629
Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
SK L D APA ++P + EGQ F+C+
Sbjct: 26630 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26659
Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S
Sbjct: 26660 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26719
Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
+A L + L V + V+ + S SL+ +++S S+ +
Sbjct: 26720 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26762
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
+ S ++S E K S ++ Q ++ +SSS +
Sbjct: 26763 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26807
Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
G+ + + E S + KA R IP PK E+ P
Sbjct: 26808 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 26839
Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480
+ E + + C +G P PEV W G + QE G + L ++ + +
Sbjct: 26840 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 26899
Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERL 507
D G Y+ + N G S + + + +
Sbjct: 26900 DGGLYTLSLGNEFGSDSATVNIHIRSI 26926
Score = 96.3 bits (238), Expect = 2e-19
Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)
Query: 1228 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
P T PP + + F + +R GE+ L G+ +G +W K + E + +
Sbjct: 10311 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10370
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346
+ + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++
Sbjct: 10371 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10430
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405
+ +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+
Sbjct: 10431 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10490
Query: 1406 AINVYGTSEPSQESELTT-----VGEKPEEP 1431
A N+YG S+P + V + P++P
Sbjct: 10491 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10521
Score = 95.9 bits (237), Expect = 3e-19
Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
+G + + + K P P I D V GE + + T +W K
Sbjct: 7869 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 7925
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P
Sbjct: 7926 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 7985
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392
ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+
Sbjct: 7986 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8044
Query: 1393 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449
DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + +
Sbjct: 8045 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8103
Query: 1450 RTVTINTEQKVSDFYDIEERLGSGK 1474
+ + K+ + I E++ G+
Sbjct: 8104 KPPLYDGGSKIMGY--IIEKIAKGE 8126
Score = 95.9 bits (237), Expect = 3e-19
Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%)
Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561
++A +E+ P ++ EG C + ++TW + ++ + T
Sbjct: 25064 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25122
Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608
E GVA L+++D D GTY C N G+ S A + V KK R+
Sbjct: 25123 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25182
Query: 609 SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
++ + L P + T P++ + G V V ++ +P P V W +G +I+ +
Sbjct: 25183 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25237
Query: 668 D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720
+ + FE + L I V +D YT A N GE +A LTV P D T +
Sbjct: 25238 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25297
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
P F + GQSV ++G P PT+ W +DG+ L + + D + L
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25357
Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
++ P G Y + N G SCQ L ++
Sbjct: 25358 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389
Score = 95.5 bits (236), Expect = 4e-19
Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)
Query: 1249 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G
Sbjct: 13893 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 13952
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY
Sbjct: 13953 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14011
Query: 1368 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
+E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q +
Sbjct: 14012 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14068
Query: 1424 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
V P P ++ EVS+ V T T++ ++ V D
Sbjct: 14069 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14101
Score = 94.7 bits (234), Expect = 7e-19
Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VRAG S+ +F + G TW K I +EN+E+ + L I + G +
Sbjct: 14291 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14348
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y +
Sbjct: 14349 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14407
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E
Sbjct: 14408 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14467
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478
P P D + + D + + + + K++ + +R GS ++ +
Sbjct: 14468 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14517
Score = 94.7 bits (234), Expect = 7e-19
Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++
Sbjct: 19289 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19345
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L
Sbjct: 19346 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19405
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N
Sbjct: 19406 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19465
Query: 1410 YGTSEP 1415
YG EP
Sbjct: 19466 YGVGEP 19471
Score = 94.4 bits (233), Expect = 9e-19
Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
+RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y
Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23018
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y +
Sbjct: 23019 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23077
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E
Sbjct: 23078 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23137
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
P P ++EV D V TVT+ E+ + D
Sbjct: 23138 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23164
Score = 94.0 bits (232), Expect = 1e-18
Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y
Sbjct: 18909 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 18968
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y +
Sbjct: 18969 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19027
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E
Sbjct: 19028 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19085
Query: 1428 PEEP 1431
P P
Sbjct: 19086 PFSP 19089
Score = 93.2 bits (230), Expect = 2e-18
Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 1250 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301
+AG + + + G +W K +K +++ H ++E +EN S + I +
Sbjct: 9326 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9385
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+ H G Y++ +NK G + A + V+D P PP SDI S LSW DGG
Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9444
Query: 1362 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + +
Sbjct: 9445 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9504
Query: 1421 LTTVGEK--PEEPKDEVEV 1437
TT + P +P ++++
Sbjct: 9505 RTTARDPIYPPDPPIKLKI 9523
Score = 92.4 bits (228), Expect = 4e-18
Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
+ P F +L +K A FE R+ G P V W +G+P+ + R + G
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
SL + D G TC ATN G + L V E S ++ P K L
Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773
Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
+ ++ G + P V V EG+ RF C++TG PQP+V W
Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
++ S R V +G+ L+I D G N G +L IQ + RS
Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891
Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
+R + + E K+D ++K +R +
Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951
Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
SK + + T V K+ ++ + EE+K A
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
T PT +P +I + ++ PK + QSQ V + FR V
Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2056
Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
G P PE W+ G + R + + + L + DS + A N G+ S
Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2116
Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557
L V+ ++ +F+ L+D E P ++ W +G +
Sbjct: 2117 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2172
Query: 558 --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
R + V L I D Y+C V V ++ ++ ++
Sbjct: 2173 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2218
Query: 616 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672
A + F++ L D++V + + VS PE I W HN E++ + +
Sbjct: 2219 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2269
Query: 673 QRGTQHSLCIQEVFPEDTGTYT 694
R + +L +++V ED G Y+
Sbjct: 2270 SRRGRQNLTVKDVTKEDQGEYS 2291
Score = 92.4 bits (228), Expect = 4e-18
Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290
P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++
Sbjct: 18208 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18264
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ L + + G Y L + N G++ + + V+D+P PP G + + + L
Sbjct: 18265 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18324
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N
Sbjct: 18325 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18384
Query: 1410 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438
YG EP + +T KP P EVS
Sbjct: 18385 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18414
Score = 92.4 bits (228), Expect = 4e-18
Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
T + TV+ T + MP + I P AG VEL + G P +W
Sbjct: 23226 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23279
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
+++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP
Sbjct: 23280 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23339
Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394
G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L
Sbjct: 23340 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23399
Query: 1395 LPDHEYKFRVRAINVYG 1411
+EY FRV A N +G
Sbjct: 23400 TEGNEYVFRVAATNRFG 23416
Score = 92.0 bits (227), Expect = 5e-18
Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+P+T P + +N+ + EG + E + GYP P VTW+R I S F +
Sbjct: 892 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
G L+I ED G++TC A N +G + L V+ S + V++ T R
Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009
Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
F S V T S+ E P F TK + EG F C++ G P+P V W
Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069
Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
K VPL R VS +++ G L I DD G YT +V N G+ S SA L
Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 92.0 bits (227), Expect = 5e-18
Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
+AGE V++ G P T TW K K + +EN+++ S LTI + G Y
Sbjct: 20787 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 20846
Query: 1310 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I
Sbjct: 20847 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 20905
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E
Sbjct: 20906 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 20965
Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474
P P ++ + D + + + + ++++ + ER G G+
Sbjct: 20966 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21009
Score = 91.7 bits (226), Expect = 6e-18
Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y
Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16803
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y +
Sbjct: 16804 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 16863
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
+ D+ W + AT T+ V L EY+FR+ A N YG S
Sbjct: 16864 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 16909
Score = 91.3 bits (225), Expect = 8e-18
Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)
Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301
KV+AGE V + VTG W K I++ +V SE ++L+I A
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS
Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9030
Query: 1362 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418
+ Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ +
Sbjct: 9031 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9090
Query: 1419 SEL 1421
++
Sbjct: 9091 DKV 9093
Score = 91.3 bits (225), Expect = 8e-18
Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)
Query: 1226 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
P P PP++I +Q ++ G+++ L + G TW K +
Sbjct: 10707 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10766
Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
+ V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+
Sbjct: 10767 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 10823
Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401
IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y
Sbjct: 10824 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 10883
Query: 1402 FRVRAINVYG 1411
FRV A N YG
Sbjct: 10884 FRVAAENQYG 10893
Score = 91.3 bits (225), Expect = 8e-18
Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)
Query: 1232 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
PKA +PP+I + +KV RA ++ LF + G W R + +
Sbjct: 15352 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15409
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
+E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++
Sbjct: 15410 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15468
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
+S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV
Sbjct: 15469 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15528
Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431
A N YG P++ +E E+P P
Sbjct: 15529 LAENEYGIGLPAETAESVKASERPLPP 15555
Score = 90.5 bits (223), Expect = 1e-17
Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)
Query: 1249 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
V AG + + V+G P T TW M R QE+ +E + S + I ++ H G
Sbjct: 10039 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10095
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y
Sbjct: 10096 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10154
Query: 1367 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
IE +S + W + T + VQ L+ Y FR+ A N G + SE +
Sbjct: 10155 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10214
Query: 1426 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475
E PE P+D +EV EV TVT+ D Y +E RL G+ KF
Sbjct: 10215 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10266
Query: 1476 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524
K T + + KE + +S +N + K C
Sbjct: 10267 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10308
Score = 90.1 bits (222), Expect = 2e-17
Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
+RAG S+ LF + G W K +I+++ + V +S + L + + G Y
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16514
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y +
Sbjct: 16515 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16573
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E
Sbjct: 16574 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16633
Query: 1428 PEEP 1431
P+ P
Sbjct: 16634 PQPP 16637
Score = 90.1 bits (222), Expect = 2e-17
Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)
Query: 1228 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278
P P +++++P+ D++ + G V G + T PI C W K + I
Sbjct: 23621 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23680
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G
Sbjct: 23681 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23738
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397
DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L +
Sbjct: 23739 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23798
Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454
EY FRV A N +G S+P + E T PE P + EV D + + +
Sbjct: 23799 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 23858
Query: 1455 NTEQKVSDFY 1464
+ +V+ +Y
Sbjct: 23859 DGGSRVTGYY 23868
Score = 89.4 bits (220), Expect = 3e-17
Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)
Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679
AP F Q L + V++GS T +SG P PEV W +G I S +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122
Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
+ + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 800 VGECSCQVSLMLQ 812
VG + L++Q
Sbjct: 182 VGRATSTAELLVQ 194
Score = 89.0 bits (219), Expect = 4e-17
Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%)
Query: 408 QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467
Q++ P P+ V E +T +FRC V+G P+P+V W+L G +R+ + Y+
Sbjct: 1789 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1846
Query: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527
G HYL ++ ++ D+G TA N +G + L++++ F SVL+
Sbjct: 1847 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1900
Query: 528 GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+ V LQ V+ P + L + I + + E+ EL +
Sbjct: 1901 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 1958
Query: 576 EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618
+ G Y + E L + W E+K + E + +
Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2018
Query: 619 KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
KP AP + + V GS V+V G P PE W NG +I+ S+
Sbjct: 2019 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2078
Query: 670 H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728
+ + L I++V ED+ + +A N AGE + A L VQ T F + +
Sbjct: 2079 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2135
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758
V A ++ +PF V W +DG
Sbjct: 2136 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2165
Score = 87.8 bits (216), Expect = 9e-17
Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)
Query: 1232 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285
PK + P I + VRAG + LF V G TW K +++ +
Sbjct: 12100 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12156
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+
Sbjct: 12157 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12215
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
+S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV
Sbjct: 12216 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12275
Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431
A+N YG P+ + + EP
Sbjct: 12276 TAVNEYGPGVPTDVPKPVLASDPLSEP 12302
Score = 87.8 bits (216), Expect = 9e-17
Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)
Query: 1228 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
P P P I+ PE + +RAG ++ L+ V G P TW K +
Sbjct: 13178 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13237
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
++ + +++++ + L + G Y L +EN G ++ + + V+D P PP
Sbjct: 13238 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13296
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397
+I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L
Sbjct: 13297 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13356
Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428
Y FRV A N YG +P + + + P
Sbjct: 13357 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13387
Score = 87.8 bits (216), Expect = 9e-17
Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)
Query: 1237 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
PP+I + +KV RA ++ LF + G W K + ++ ++E + + +
Sbjct: 18607 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18664
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW
Sbjct: 18665 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18723
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG
Sbjct: 18724 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783
Query: 1413 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
P++ +E V E P P V +V T TI E+ SD
Sbjct: 18784 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 18825
Score = 87.0 bits (214), Expect = 2e-16
Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VRAG S + G TW R++ + ++ +++E N ++L+I + G Y
Sbjct: 17539 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17596
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I
Sbjct: 17597 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17655
Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
+ +S K + +++ C TSF V++L Y FRV A N +G P + + E
Sbjct: 17656 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17715
Query: 1428 PEEP 1431
P P
Sbjct: 17716 PSPP 17719
Score = 87.0 bits (214), Expect = 2e-16
Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y +
Sbjct: 17886 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 17945
Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
E D+ TW + AT T+ + L EY+FR+ A N YG S P
Sbjct: 17946 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 17993
Score = 85.9 bits (211), Expect = 3e-16
Identities = 67/238 (28%), Positives = 104/238 (43%), Gaps = 21/238 (8%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG- 77
V P++ DS P FI N I G A V G P+P++ W NG +T
Sbjct: 3443 VYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSAD 3502
Query: 78 -RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVV 136
+F+ D SL+I ED G+YTC A+N G T+ ++ K +
Sbjct: 3503 YKFVFD---GDDHSLIILFTKLEDEGEYTCMASNDYGK-------TICSAYLK-----IN 3547
Query: 137 SKTLGDRFS---APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVT 193
SK G + + + ++ + G CPP F +L + +G F + G P P VT
Sbjct: 3548 SKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3607
Query: 194 WLKGNVPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
W K N L S + + NG ++ ++D G+Y C N G+++ +AEL +
Sbjct: 3608 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 85.5 bits (210), Expect = 4e-16
Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472
P F QS V E T F +SG P PEV+WF +G + +++ G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531
+ +SG YS A+N GQ T E L E A P+F L+ V +G
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
LQ V G P P + + +G IQ + + + E + L I +A PED GTY+ A N+
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616
+G+ + +A + V E+ ++K++ ++ A
Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211
Score = 85.5 bits (210), Expect = 4e-16
Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I D G++T A N +G ++V LTVE AVE
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
+ P F KL V +KEG + TG P P + WLK + + P ++ +
Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
G L+I D YT +N +G+ + +++++
Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602
Score = 84.0 bits (206), Expect = 1e-15
Identities = 65/256 (25%), Positives = 111/256 (43%), Gaps = 35/256 (13%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ VA + S +L V+ E P + + + ++ G A+F + G P+
Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221
Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P+++W++ Q +++G + FL D ++L++ ED YTCEA N G +
Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
L+VE P V + PP T L V EGQ R
Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F C+++G +V+W + ++PS +++ LEI +D G YT + N
Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376
Query: 240 GKASMSAELSIQGLDS 255
G+ S +A LS++ +S
Sbjct: 3377 GQVSSTANLSLEAPES 3392
Score = 84.0 bits (206), Expect = 1e-15
Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
+ G + +W K + + VE+S + L + ++ G YT+ ++N G+++
Sbjct: 13509 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
+++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W
Sbjct: 13569 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13628
Query: 1381 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
A+ + T+F V L EY FRV A N YG E
Sbjct: 13629 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13663
Score = 83.6 bits (205), Expect = 2e-15
Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 1237 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
PP+I FP VRAG ++++ ++G T + ++ + E +
Sbjct: 19976 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20035
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
+ + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W
Sbjct: 20036 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20095
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G
Sbjct: 20096 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20155
Query: 1413 SE 1414
S+
Sbjct: 20156 SD 20157
Score = 83.2 bits (204), Expect = 2e-15
Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)
Query: 1238 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
P I++F + +++GES+ + V G TW K +I++ +M++ + +
Sbjct: 21458 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21517
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W
Sbjct: 21518 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21577
Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G
Sbjct: 21578 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21637
Query: 1413 SEP 1415
P
Sbjct: 21638 GRP 21640
Score = 82.8 bits (203), Expect = 3e-15
Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)
Query: 882 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938
H EE+ QQ + +++ ++S ++E + PA + + + VKP+ +
Sbjct: 676 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726
Query: 939 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997
SE K + + S + K T V P+ A+P F K +P
Sbjct: 727 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783
Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055
A + K LS + + + + A T+KP AE L A
Sbjct: 784 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840
Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095
+ KS + E+KK+V + GTT E+R E
Sbjct: 841 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894
Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + +
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
I +A ED G + C A N+AG SC V V + E T E + K +
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
+D ++ ++ A P A P I P QK+ G SV +V G W K
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071
Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325
+ KV N + G KL I + G YT++V NK G A +L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 82.4 bits (202), Expect = 4e-15
Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%)
Query: 405 MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457
++G++ + K + +P Q+V E V+ +VS + E W +G V+
Sbjct: 2294 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2352
Query: 458 EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517
+ + + D SH L + D+G YS T L S + +V +V + P
Sbjct: 2353 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2404
Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574
LKD VIEG VL+C V V + W LN + I+ ++ + L I
Sbjct: 2405 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2462
Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
D G Y + +G+V + ++V + K ++GL DL
Sbjct: 2463 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2498
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
+ V V++S + +V+W EI+ S + E G + L + + +D G YT
Sbjct: 2499 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2557
Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753
AGE T LTV ISKP T + Q + C +A +P
Sbjct: 2558 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2605
Query: 754 WLRDGKAL 761
WLRDGK L
Sbjct: 2606 WLRDGKHL 2613
Score = 82.4 bits (202), Expect = 4e-15
Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)
Query: 1086 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
D E R++ + AP K QD+ V GK L + + P A W + L T
Sbjct: 6490 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6549
Query: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
+++ S + +K D+G YK V +N G+AE + V D P
Sbjct: 6550 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6594
Query: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
PV E T + + ++ + G S ++ G V
Sbjct: 6595 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6631
Query: 1265 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322
+ I TW+ + + E + G + + + G + +N + +R
Sbjct: 6632 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6691
Query: 1323 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W
Sbjct: 6692 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6744
Query: 1383 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
T R+ S V D++ EY FRVRA N G +PS + V + E P V ++
Sbjct: 6745 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6804
Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493
D+ + V + + I ER GK + +LV + T KV K
Sbjct: 6805 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 6864
Query: 1494 FFKAYSAKEKENIRQEISIMNCL 1516
+ SA+ K + I+ L
Sbjct: 6865 YLYRVSAENKAGVSDPSEILGPL 6887
Score = 82.4 bits (202), Expect = 4e-15
Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
V+AG S + G W K ++ + V+ +++ + LTI A + G Y
Sbjct: 19701 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19758
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I
Sbjct: 19759 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 19817
Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
E +++ K W + C S+ V +L Y FRV N +G P++ E + EK
Sbjct: 19818 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 19877
Query: 1428 PEEPK 1432
P P+
Sbjct: 19878 PSPPE 19882
Score = 82.4 bits (202), Expect = 4e-15
Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G
Sbjct: 24410 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24469
Query: 662 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
EI + + ++ +G H L I V +D Y A N G V A L V+ P
Sbjct: 24470 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24529
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L
Sbjct: 24530 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24588
Query: 780 VLKK-VQPWHAGQYEILLKNRVG 801
V V+ AG Y + KNR G
Sbjct: 24589 VFPNGVERKDAGFYVVCAKNRFG 24611
Score = 82.0 bits (201), Expect = 5e-15
Identities = 87/338 (25%), Positives = 138/338 (40%), Gaps = 26/338 (7%)
Query: 384 TRQPGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIP 441
TR G VV+ + ++ +EG RD + + Q E K+ V+F +
Sbjct: 3073 TRMSDAGKYTVVAGGNVSTAKLFVEG-RDVRIRSIKKEVQVIE-KQRAVVEFEVNEDDV- 3129
Query: 442 KPEVAWFLEGTPVRRQEGSIEVYE-DAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
+ W+ +G + Q Y + H + + + R D+G Y+ A G+ S
Sbjct: 3130 --DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA----GRNRSSV 3183
Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA--- 557
TL V P L+ V G+ + G P P+I+W Q +
Sbjct: 3184 TLYVNA----PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3239
Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
+ + L + +A PED YTC A+N G + SA ++V E + +PV P
Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEMPVYP 3298
Query: 618 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 677
P + L D +G +VSG +V W +I+ S F Q
Sbjct: 3299 -----PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDT 3352
Query: 678 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
+ L I E +PED GTYT A N+ G+V + A L+++ P
Sbjct: 3353 YQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3390
Score = 82.0 bits (201), Expect = 5e-15
Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)
Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
R D+M L E P F LP N G +F + +PEP VTW+++GQ I G +
Sbjct: 25182 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25241
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ + +G + L I++V +D +YT A N G +LTV L P
Sbjct: 25242 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25294
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
TL P F L +EGQ F +++G P P + W K
Sbjct: 25295 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25335
Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
PL + + E L I +D G Y N +G S A L ++ L
Sbjct: 25336 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25395
Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
+ F + + V+K++ + L E+
Sbjct: 25396 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25427
Score = 81.6 bits (200), Expect = 6e-15
Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306
V+AG+++ L V G W K + + S +K++ + SK ++ A++ G
Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11775
Query: 1307 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y
Sbjct: 11776 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 11834
Query: 1367 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423
+E ++ W AT + V L+ +EY FRVRA N GT P++ + T
Sbjct: 11835 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 11894
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464
+KP P D EV+ ++E V + + + ++ ++
Sbjct: 11895 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 11934
Score = 81.6 bits (200), Expect = 6e-15
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)
Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
+ ED G YTC A N GEV T + L +Q P + K + A +G ++ +
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24152
Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800
G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N
Sbjct: 24153 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24211
Query: 801 GECSCQVSLMLQN 813
G + + +Q+
Sbjct: 24212 GTVDAILDVEIQD 24224
Score = 81.3 bits (199), Expect = 8e-15
Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%)
Query: 416 FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
F + Q KE T+ F CE S P +V W+ +G V + ++ D H+L +
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2187
Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
L T D+ YSC + + + +L V F L+D V E L+
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2241
Query: 535 CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
C V + W N ++ T G L ++D ED G Y+ + +
Sbjct: 2242 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2296
Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
KK++ K + KP LQGLSD KV +G V + V+VS
Sbjct: 2297 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2338
Query: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707
E +W+ +G E+Q S+ H H L I+++ ED G Y+ +++G V
Sbjct: 2339 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2397
Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
+V I+ + V G ++ C ++ +V W + + + K
Sbjct: 2398 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2444
Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
+ + LV+ + G Y++++ RV E +C +S+
Sbjct: 2445 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2484
Score = 80.9 bits (198), Expect = 1e-14
Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+ E ++ F E+S P W L+G + R + E+ + G +L L K + +G
Sbjct: 4911 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 4968
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
A NA + L V E+ F+ LKD V E + +C + T
Sbjct: 4969 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 5017
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601
+ W I+ + + HI D+ +D G YT E + S +VT
Sbjct: 5018 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 5075
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
K F+ L D V +G T ++S + V+W N
Sbjct: 5076 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 5114
Query: 662 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
++ S G H L ++EV +D + E+ + A L V E P
Sbjct: 5115 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 5166
Query: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
+F K TA + + C ++ D V W +DG+ + + + + L +
Sbjct: 5167 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 5223
Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837
KK G+Y C C N + A L + +P ++ G
Sbjct: 5224 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 5274
Query: 838 ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889
+ D +G W +GQ D E + K + T + + +A
Sbjct: 5275 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 5330
Query: 890 QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949
+ L ++L + LS D+K ++ F + R+ PKT R + Q
Sbjct: 5331 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 5380
Query: 950 QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007
++ D R L K GT + V + A F + + +G E + K
Sbjct: 5381 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 5434
Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067
+ K ++ + + V + +K N + T + + + + + S + ++L
Sbjct: 5435 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 5493
Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
D + + + G + K + +G P F KLQD E +++LQC++S A
Sbjct: 5494 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 5549
Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ W +GK +K +K ++ +G + ++KAL D G Y C D G + S ++ +
Sbjct: 5550 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5605
Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
+D E+K RP S+ V+ TE+
Sbjct: 5606 EDR---------EIKLVRPLHSV-EVMETET 5626
Score = 80.9 bits (198), Expect = 1e-14
Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)
Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
PPKA + ++ + +RAG + L V G W K K++ E + ++ +
Sbjct: 22546 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22603
Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
+ I + G YTL V+N G++ V + V+D P P G S + TL
Sbjct: 22604 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22662
Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
+W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N
Sbjct: 22663 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22722
Query: 1410 YG-----TSEPSQESELTTVGEKPEEPKD 1433
YG SEP T+ P P++
Sbjct: 22723 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22751
Score = 79.7 bits (195), Expect = 2e-14
Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
+AG+++++ V G T TW K + +++++ + E + + L I + G Y
Sbjct: 14581 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14640
Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
L N +G + + V D P PP G ++ S +T SW DGG + +Y +E
Sbjct: 14641 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14700
Query: 1370 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411
+ + + TW ELA T T++ L EY+FRV+A N YG
Sbjct: 14701 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14743
Score = 79.3 bits (194), Expect = 3e-14
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 1738 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1797
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284
Query: 1798 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 79.3 bits (194), Expect = 3e-14
Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%)
Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R
Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079
Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
LVI V ED +A N +G L V+ AKQL
Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127
Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199
F +L VV KE M F C+ T P +V W K +
Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
+ + + + L I ++ D Y+C++V +A+L ++G A
Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2222
Query: 260 FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
FV+E + E+ ++S E+ + +E + K + +RG +
Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282
Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363
+ E K +CK + P +LQ S + VQ E + GV
Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341
Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420
G+E +P+ + L +D+ + A IP G S S
Sbjct: 2342 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400
Query: 421 QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
+K+ ++ C+VS V W+L + + + ++ L +
Sbjct: 2401 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2459
Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
+ D G Y G++ + L VE++ ++ L+D E Q+ V +
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2508
Query: 536 SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
+ + + + W + I+ + + + +L + + + +D G YT A G+
Sbjct: 2509 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2563
Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
S +TV A SKP L+D V + + +V+ NP
Sbjct: 2564 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2602
Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+ WL +G + + + E G + L I +D G YT + S +T A L V
Sbjct: 2603 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2658
Query: 713 QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
+ I K +++T + Q + + + V W+++G L
Sbjct: 2659 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701
Score = 79.0 bits (193), Expect = 4e-14
Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471
P+F ++ + V+F ++ P+P V W+ G ++ + + D G +
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25252
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528
L + T D Y+ A N G+ SC L V + P F +L + EG
Sbjct: 25253 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 25312
Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584
Q + V G P P + W +GQP+ + G+ LHI+D LPED G Y
Sbjct: 25313 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 25372
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEY 611
A N G SC A + V E+ +K E+
Sbjct: 25373 ATNTAGSTSCQAHLQV-ERLRYKKQEF 25398
Score = 78.6 bits (192), Expect = 5e-14
Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)
Query: 1225 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276
+P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K
Sbjct: 8167 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8224
Query: 1277 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310
++QE E + ++NS+ G S+L + + + G Y +
Sbjct: 8225 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8284
Query: 1311 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370
VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E
Sbjct: 8285 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8343
Query: 1371 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
D + W + +T R ++V L+ EY FRVRA N +G P L V +
Sbjct: 8344 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8401
Query: 1428 PEEPKD 1433
P P D
Sbjct: 8402 PFGPPD 8407
Score = 78.2 bits (191), Expect = 7e-14
Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%)
Query: 36 ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94
I P +++ + EG A E +V V W+ N + I R + ++GT LVI+
Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2459
Query: 95 AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154
H D G Y G + L+VE
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2487
Query: 155 IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214
K L + E Q F +++ V W + ++PS++ +
Sbjct: 2488 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2539
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272
+ L + + +DD G YT +G+ S +L++ G + ++ +T A + +
Sbjct: 2540 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2594
Query: 273 KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329
EV N SK L + + N S G A K+ + K S
Sbjct: 2595 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2654
Query: 330 RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378
+ + ++KT ++T+ + P G+ GV+ S E+
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2714
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
+ + + + V R + + K KP+ EN TV F VS
Sbjct: 2715 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2773
Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
P V WF + ++ + + + H L L D+G Y+ GQL C
Sbjct: 2774 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2827
Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
L VE L + + +K+ V E + +C V VP + WL NG I+ +
Sbjct: 2828 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2879
Query: 559 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
+ + +L I + ED YT + N QVS + VT
Sbjct: 2880 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2921
Query: 616 APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674
PI + L D+ + +T V V+ WL NG EI+ ++ +
Sbjct: 2922 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 2973
Query: 675 GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
HSL I+ V D YT AG+ + A L V+ H F + +
Sbjct: 2974 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3025
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
+ + C ++ +P TV W++D + L + T ++ + + V L++ + AG+Y +
Sbjct: 3026 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083
Query: 795 LLKNRV 800
+ V
Sbjct: 3084 VAGGNV 3089
Score = 78.2 bits (191), Expect = 7e-14
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)
Query: 1228 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
P T A + P + F + +V + + TG T TW K ++ + +K
Sbjct: 6886 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 6945
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI
Sbjct: 6946 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7004
Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404
S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V
Sbjct: 7005 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7064
Query: 1405 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433
A N G EP+ E ++T P+ P++
Sbjct: 7065 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7096
Score = 78.2 bits (191), Expect = 7e-14
Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
PA ++L V ++ +L + D + I L K + F + + + ++
Sbjct: 22049 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22108
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
E+ + + ++ AKNDAG +E P+ + V+
Sbjct: 22109 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22140
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+K+ T + Q+I +AG + ++G TW +
Sbjct: 22141 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22190
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G
Sbjct: 22191 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22250
Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396
S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L
Sbjct: 22251 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22310
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
EY FRV + N +G S+P + + + + E P P
Sbjct: 22311 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22343
Score = 77.4 bits (189), Expect = 1e-13
Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%)
Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
S+DVV + G + A P F +KP Q++ E +V F C+V G PKP V W
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072
Query: 451 GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509
G P+ + + G L + D+G Y+ N G+ S S +L +E
Sbjct: 1073 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567
+ S +L V FV + V G P + + + ++ +A+
Sbjct: 1132 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625
+ ++ + + + E + ++ T E+ + + + + ++ S+ F
Sbjct: 1188 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1247
Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683
+ + ++++G VT ++SG P P++ W +G I+ E + F Q G + SL I
Sbjct: 1248 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1306
Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732
V PED G YT A N G L V+ P +I PRSV+
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366
Query: 733 S 733
S
Sbjct: 1367 S 1367
Score = 77.0 bits (188), Expect = 2e-13
Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI
Sbjct: 16733 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16792
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++ +D G Y N GQ S ++ D P + K P
Sbjct: 16793 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 16835
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
D + + PP QI + ++ T W
Sbjct: 16836 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 16879
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332
+ + +KV + G++ + + EN+ G A + +V +P
Sbjct: 16880 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 16927
Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385
PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT
Sbjct: 16928 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 16981
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
T F Q+L EY+FRV A N+ G + S+ SE + + P
Sbjct: 16982 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17027
Score = 76.6 bits (187), Expect = 2e-13
Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+
Sbjct: 6328 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6386
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206
+D Y C ++ +A + + V+ +AP ++ E+ +
Sbjct: 6387 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6446
Query: 1207 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241
++++ V G + + K + + A P+I
Sbjct: 6447 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6506
Query: 1242 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301
+D V G+ + + W K + + ++ + + IL A+
Sbjct: 6507 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6563
Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
+ G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS
Sbjct: 6564 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6622
Query: 1362 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418
+ Y +E D KTW LAT R+ S F V L EY FRV A N GT EP +
Sbjct: 6623 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6681
Query: 1419 SELTTVGEKPEEPKDEVEVSDDD 1441
K + P + V+ D
Sbjct: 6682 DNPVEARSKYDVPGPPLNVTITD 6704
Score = 76.3 bits (186), Expect = 3e-13
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 1721 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1779
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918
Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977
Query: 1840 ATCTAELIVETMEEGEGE 1857
+ + L V+ EE E E
Sbjct: 978 VSTSCYLAVQVSEEFEKE 995
Score = 75.9 bits (185), Expect = 3e-13
Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%)
Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678
K P+ L D +G V +T ++ EV W + E F Q +
Sbjct: 4239 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4296
Query: 679 SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737
+L I +V ED G Y CEA N +G+ T A LTV + P K + +LG
Sbjct: 4297 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4353
Query: 738 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797
+C I P W + G+ + ++ + ++ + +L + + Q G+Y
Sbjct: 4354 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4412
Query: 798 NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
N G SC +L + R L R+P E++ S+
Sbjct: 4413 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4459
Query: 854 PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 913
P + +E + E V K+ + + + EV + R+ +K+ T +
Sbjct: 4460 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4512
Query: 914 DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 970
IP + + + +V KP V E + +P V V+ KK +K P E
Sbjct: 4513 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4569
Query: 971 VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 1027
P P + G KK P+ + + E P + + PLK V
Sbjct: 4570 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4622
Query: 1028 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1073
K + +G++ E L A K N++ + K D K+
Sbjct: 4623 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4682
Query: 1074 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1124
+ C + G+ T K + K ++V V +G+ L L C+++ +
Sbjct: 4683 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4742
Query: 1125 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1183
++W +GK ++ I+ G + +++I A D G Y +N A ECS
Sbjct: 4743 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4799
Query: 1184 QVTV 1187
V V
Sbjct: 4800 CVKV 4803
Score = 75.9 bits (185), Expect = 3e-13
Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)
Query: 1052 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105
N++P ++LK +E + D + + + +A G ++ + SE+ P +
Sbjct: 7838 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 7897
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D
Sbjct: 7898 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 7957
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
G+Y +N G A S V V P ++K+ SD T
Sbjct: 7958 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 7999
Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
PP+ G PI ++ R++ ++
Sbjct: 8000 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8031
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343
V + EN T+ + + NK+G + N + P P P ++
Sbjct: 8032 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8091
Query: 1344 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395
+ ++T++W YDGGS + Y IE + WK C ++ + L
Sbjct: 8092 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8148
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442
EY+FRVRA N G SEPS+ + T + + PK +EV DE
Sbjct: 8149 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8199
Score = 73.9 bits (180), Expect = 1e-12
Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
VKE Q V F CEV+ + WF + I + +D + L + A D
Sbjct: 6154 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 6211
Query: 485 YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
Y+ + +N +G+ + + L VE + V P LKD +E + C V V
Sbjct: 6212 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 6266
Query: 544 RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
+ W NG+ + + H I+D D G Y VT
Sbjct: 6267 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 6310
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
+ KS +E L+ AP++ F++ L D V + + Q+S V W NG
Sbjct: 6311 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 6362
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719
EI+E + + FE+ G+ H L I++ +D Y C + +++A L V+E P +
Sbjct: 6363 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 6418
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
+P P+ + + G V+ + D V WLR+ + + H +++ + L
Sbjct: 6419 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 6471
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVS 808
+ ++P G+Y + K++ +++
Sbjct: 6472 QICDIKPRDQGEYRFIAKDKEARAKLELA 6500
Score = 73.9 bits (180), Expect = 1e-12
Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V+V G L + +S P + + +G LK T ++++++++ D G
Sbjct: 19989 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20048
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224
Y+ A N +G + + V D P P V+ TE T+K
Sbjct: 20049 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20094
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+P PK + + I+ ++ S ++ +V+ T + T MK K E+
Sbjct: 20095 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20144
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344
+EN + + + S V L P PP+ TP +++
Sbjct: 20145 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20185
Query: 1345 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402
S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F
Sbjct: 20186 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20245
Query: 1403 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
RV A N G +PS SE + E P++ V ++D + + ++ + K++
Sbjct: 20246 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20304
Query: 1463 FYDIEER 1469
Y +E R
Sbjct: 20305 -YIVERR 20310
Score = 73.6 bits (179), Expect = 2e-12
Identities = 33/91 (36%), Positives = 56/91 (61%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328
R+++ ++ +++ G+ L + ++ + + EN+ G S + T +
Sbjct: 23770 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 23829
Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386
+ P+PP+ P D+ SS++LSW DGGS V Y IE +++ W +
Sbjct: 23830 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 23889
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437
T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+
Sbjct: 23890 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 23942
Score = 72.4 bits (176), Expect = 4e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)
Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++
Sbjct: 8601 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8656
Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347
N S+L I A ++ G Y + N GS+ A + V D P P R
Sbjct: 8657 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8716
Query: 1348 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407
L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A
Sbjct: 8717 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8775
Query: 1408 NVYGTSEPSQESELTTV 1424
N +G P + + V
Sbjct: 8776 NKFGCGPPVEIGPILAV 8792
Score = 71.6 bits (174), Expect = 7e-12
Identities = 74/293 (25%), Positives = 111/293 (37%), Gaps = 39/293 (13%)
Query: 13 SKTSLSVDPSRVDS----MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
+ SLSV+ V S MP+ PA I P ++ EG A+F+ RV G + +V+W+
Sbjct: 3276 TSASLSVEVPEVVSPDQEMPVYP-PAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYS 3333
Query: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE---- 124
+ I RF T+ L I + ED G YT A+N G T L++E
Sbjct: 3334 KDKKIKPS-RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES 3392
Query: 125 ---------------------------GSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
G + +L +++TL +P T+
Sbjct: 3393 ILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEK 3452
Query: 158 E-CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
E P F ++ + G + S + G P+P++ W V L PSA
Sbjct: 3453 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 3512
Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269
L I +D G YTC+ N GK SA L I ++ E+ S
Sbjct: 3513 SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKS 3565
Score = 71.6 bits (174), Expect = 7e-12
Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
+D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T
Sbjct: 20667 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20725
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+
Sbjct: 20726 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20779
Score = 71.2 bits (173), Expect = 9e-12
Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324
P T W++ K + +V+ N K + +L EN G + +
Sbjct: 7427 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7475
Query: 1325 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
+ + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W
Sbjct: 7476 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7535
Query: 1381 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437
+A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV
Sbjct: 7536 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7595
Score = 70.9 bits (172), Expect = 1e-11
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P
Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538
Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P + W +N I + ++ G +G +L I + +D YT A N +G
Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597
Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
++ VE FA+ + + G +AP +E +G + P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657
Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
F KL + +K F C++T G P V WL PL+ + R+ + + G L+
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
D G+ TC N G SA L ++ +S V E++
Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759
Score = 70.9 bits (172), Expect = 1e-11
Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%)
Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
SE +GT P F +++ + ++ G L V P I W NG L + +G
Sbjct: 3450 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3509
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
S+ I ED G Y C+A ND G+ CS + + N+K K
Sbjct: 3510 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3555
Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
TE+++ V K P PP ++ + + G V G T T
Sbjct: 3556 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3607
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329
W K KQ+ S + + ++ NGS I+ ++E G Y EN LG L V+
Sbjct: 3608 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3667
Query: 1330 KPDPPAGTPC 1339
+ TPC
Sbjct: 3668 EDTDMTDTPC 3677
Score = 70.9 bits (172), Expect = 1e-11
Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G
Sbjct: 21076 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21135
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y + N C++ V P + T P K + P
Sbjct: 21136 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21166
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283
I+F E + +SV L V G ITC ++ R+ Q +
Sbjct: 21167 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21208
Query: 1284 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337
M + + K+ L E+ + + EN+ G Q V+ +V K P PP G
Sbjct: 21209 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21265
Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395
P ++ S ++L+W YDGGS V + +E + + W+++ T + L+
Sbjct: 21266 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21325
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455
+Y+FRV A N G S PS S+ T+ P +P + D V T+T+
Sbjct: 21326 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21377
Query: 1456 TEQKVSD------FYDIEERLGSGKF 1475
+ D Y IE+R G+ ++
Sbjct: 21378 WNPPLRDGGSKIVGYSIEKRQGNERW 21403
Score = 70.5 bits (171), Expect = 1e-11
Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A + I+ L+V +D F +P +++ + E A+FE + E
Sbjct: 4967 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5015
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W + I S +F + + LVI+ +D G YT E
Sbjct: 5016 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5060
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
VEG K R + KF + L VKEG+ F
Sbjct: 5061 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5097
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C+++ + V W K + L S V +S + LE+ V DD+ V +
Sbjct: 5098 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 5152
Query: 242 ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283
S +A+L + D + + A D V K+V K+
Sbjct: 5153 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 5212
Query: 284 KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337
K D L K K +G G+ AN + R K+E P + V
Sbjct: 5213 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 5267
Query: 338 LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397
+ I L V + + G + + E Q G+ + +V +
Sbjct: 5268 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 5326
Query: 398 AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456
AAN + + P P S +V E KF CEVS PK W L+GT
Sbjct: 5327 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 5383
Query: 457 QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516
+ E+ +D H + + A D Y A + +L + + F
Sbjct: 5384 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 5434
Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576
+ LKD E + V + + R+ W N Q + RS + +QD
Sbjct: 5435 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 5485
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
T+ L+ + Q+ A SE L V P F L D ++
Sbjct: 5486 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 5534
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
+V + ++S P V W +G EI+ S++ + G + L +++ D G YTC+
Sbjct: 5535 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 5593
Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
G +T L +++ + + SV ++ I+ D +W
Sbjct: 5594 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 5644
Query: 757 DGKALCKDTGHFEVLQNEDVFTLVL 781
G+AL + T E+ + + +LVL
Sbjct: 5645 KGEALLQ-TPDCEIKEEGKIHSLVL 5668
Score = 70.5 bits (171), Expect = 1e-11
Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L + V G K+ L V+ P I WT LK K I + +V+I +
Sbjct: 7200 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7259
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y A N G+A +V V D P PP +D T +
Sbjct: 7260 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7301
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
PP+ +I + +++ E W K ++++
Sbjct: 7302 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7345
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339
K T L +E+ + + EN G Q + +T + DPP G P
Sbjct: 7346 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7392
Query: 1340 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396
SDI ++TL+W DGGS + Y +E D W + T++ V+ L
Sbjct: 7393 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7452
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
+Y+FRV A N+ G +PS+ +E + + + P
Sbjct: 7453 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7487
Score = 70.1 bits (170), Expect = 2e-11
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1815
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 69.3 bits (168), Expect = 3e-11
Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)
Query: 1217 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
ESD V + P P TP A+ + + V G S + + + + W
Sbjct: 16913 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 16972
Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
K K I K +N E G + + + EN +G +A N
Sbjct: 16973 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17021
Query: 1332 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387
DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T
Sbjct: 17022 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17081
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438
F V L D Y+FRV A N G S+PS + T ++ E P +D + V+
Sbjct: 17082 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17141
Query: 1439 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495
+ E D + T + + +IEE F+ L+ K ++ G++
Sbjct: 17142 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17201
Query: 1496 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554
+A + ++ + +++ P+ VQ EK ++ + GG + E
Sbjct: 17202 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17261
Query: 1555 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598
E + E + +++ EG EY+ + IM VNK G
Sbjct: 17262 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17303
Score = 69.3 bits (168), Expect = 3e-11
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Query: 1306 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357
GC Y + EN G ++ DP P P D +++T++W +
Sbjct: 19553 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19612
Query: 1358 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS
Sbjct: 19613 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19672
Query: 1417 QESELTTVGEKPEEPKDEVE 1436
S+ E+ EEP +++
Sbjct: 19673 DSSDPQIAKEREEEPLFDID 19692
Score = 69.3 bits (168), Expect = 3e-11
Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%)
Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
E S ++EVT + E + + + A + + S+ + R SP +
Sbjct: 25732 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25791
Query: 311 --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368
S+PQP E + ++ + SP TP + PR+P SP
Sbjct: 25792 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 25826
Query: 369 EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423
ER R A F +R + + K + R+ + Q+ P+ + +S
Sbjct: 25827 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 25886
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
V Q +F V P EV W+ G ++ + I +G L +L T DSG
Sbjct: 25887 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 25945
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542
TY +N +G+ S TL V G D+ S R V
Sbjct: 25946 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 25983
Query: 543 PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
PR + + YA S+ EA + ++ + E + + +A ++ +A
Sbjct: 25984 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 26043
Query: 597 WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
++ EK ++RK + L A L + V +G + G P P V
Sbjct: 26044 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26095
Query: 655 IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714
WL G + S + + I V D G Y+ NS G+ + LT+Q+
Sbjct: 26096 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 26155
Score = 69.3 bits (168), Expect = 3e-11
Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L AP L R+ + G +F V+ P +V W+ NG + + G
Sbjct: 25873 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 25931
Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
+L I H +D G Y T + T G R V EL
Sbjct: 25932 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 25991
Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
T ++A K+ + S ++ + + ETR S+
Sbjct: 25992 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26050
Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
+ TK + V EG+ RFSC G P P VTWL+ L SAR
Sbjct: 26051 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26110
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
V+ EI V D G Y+ +V N GK L+IQ ++ V E KA
Sbjct: 26111 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26163
Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
S R V S E ++ S EA K SP+ P P + + E +
Sbjct: 26164 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26214
Query: 328 SPRTAP 333
P +AP
Sbjct: 26215 LPVSAP 26220
Score = 68.9 bits (167), Expect = 4e-11
Identities = 55/191 (28%), Positives = 77/191 (40%), Gaps = 11/191 (5%)
Query: 444 EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTASNAQGQLSCSWTL 502
EV W+ E V E + +D ++ L + K T D G Y C A N G+ + S L
Sbjct: 4271 EVNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4329
Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE 562
V V AP ++ V G C ++ P R W G+ I Y C
Sbjct: 4330 TV----VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCS 4384
Query: 563 AG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
++ L I D G YTC A N G VSC+A +TV +K LLP
Sbjct: 4385 IRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKP 4444
Query: 619 KPTAPIFLQGL 629
+P + L+ +
Sbjct: 4445 EPKEEVVLKSV 4455
Score = 68.9 bits (167), Expect = 4e-11
Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)
Query: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
P KL V V G + L+ V P + WT + T+ + +
Sbjct: 11704 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11763
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213
S+ KA D G Y A N AG V V D P N K ++ S R
Sbjct: 11764 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 11815
Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
TV P P+ + I++ E +++ W
Sbjct: 11816 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 11848
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330
+ + G+ +T L E+ + + ENK+G+ + V+ K
Sbjct: 11849 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 11896
Query: 1331 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
PDPP T + + +T+ W YDGG ++ Y +E + + W + +
Sbjct: 11897 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 11952
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
VQ+LLPDHEY+FRV+A N G EPS S V + P EP
Sbjct: 11953 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 11999
Score = 68.6 bits (166), Expect = 6e-11
Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI
Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 18957
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++A ED G Y+ N AG + V D P PP
Sbjct: 18958 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 18999
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
+ + PP+ QI + ++K + + TW +
Sbjct: 19000 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19043
Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333
+ + +K+ GS+ + + EN+ G + VV + P
Sbjct: 19044 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19091
Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386
P GTP S++ ++W DGGS V Y +E +W ANK
Sbjct: 19092 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19146
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446
T V L Y++RV A N+ G + S+ E P +P + EV++ K
Sbjct: 19147 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19205
Query: 1447 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475
+ + + K++ + L G++
Sbjct: 19206 LKWSKPHYDGGAKITGYIVERRELPDGRW 19234
Score = 68.6 bits (166), Expect = 6e-11
Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)
Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+
Sbjct: 26630 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26689
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194
++ S+ I A D G Y AKN GQ + + V + P+ E
Sbjct: 26690 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26749
Query: 1195 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235
++++ +M + + ++S + + + + K A + +
Sbjct: 26750 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26809
Query: 1236 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
+PP+I P D + G+ + + TG TW
Sbjct: 26810 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26869
Query: 1276 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ +
Sbjct: 26870 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 67.4 bits (163), Expect = 1e-10
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 1737 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 67.4 bits (163), Expect = 1e-10
Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154
P Q+LQ V V GK +S P I W + L T KF+ QE +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
+ +A PED +Y C AKND G A S ++V+ PE+ S P +P
Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
PP II +D G+ +V+GT + +W
Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
K+I+ S ++ E+ +L I A E G YT + N +G + NL++
Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Score = 67.0 bits (162), Expect = 2e-10
Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
++ + V G + + P T WT +G +KT + + + ++I+ L
Sbjct: 11020 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11079
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y+ N AG + +TV D P P + + T T+
Sbjct: 11080 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11127
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
+P P P I E Q R + +G V+
Sbjct: 11128 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11158
Query: 1284 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336
+GS T L GC + + ENK+G + V K P P G
Sbjct: 11159 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11211
Query: 1337 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390
P +DI ++ T+SW DGGS + Y +E W NKT F
Sbjct: 11212 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11266
Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
V L + Y+FRV A N+ G S+PS S+
Sbjct: 11267 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11296
Score = 67.0 bits (162), Expect = 2e-10
Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224
A+N +G + ++ V D P + K +M S R S P L G+E +
Sbjct: 12870 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 12929
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
K P A +V+ T PIT ++ K I+ E+
Sbjct: 12930 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 12962
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340
+ + ENK G + K DPP P
Sbjct: 12963 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 12999
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
S+I +T+SW + DGGS + Y +E ++ W ++ + L
Sbjct: 13000 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13059
Query: 1399 EYKFRVRAINVYGTSEPSQESE 1420
EY+FRV AIN G +PS S+
Sbjct: 13060 EYEFRVTAINKAGPGKPSDASK 13081
Score = 66.6 bits (161), Expect = 2e-10
Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)
Query: 1083 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134
G +D S+ Q ++ L D+ K L+++ S P ++W+
Sbjct: 19667 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19726
Query: 1135 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
L+T ++ + S S++IE A D G Y +N A + V V D P
Sbjct: 19727 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19782
Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254
PP T D T + A + + PE+
Sbjct: 19783 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19807
Query: 1255 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312
G P+ ++ R + S+ V + N ++L+ + Y V
Sbjct: 19808 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 19856
Query: 1313 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E
Sbjct: 19857 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 19915
Query: 1370 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429
+ K W + A +ST V L + EY FRV A N G S+P + + E+ E
Sbjct: 19916 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 19975
Query: 1430 EPKDEVE 1436
P+ +++
Sbjct: 19976 PPEIDMK 19982
Score = 65.9 bits (159), Expect = 4e-10
Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8675
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y A N G + +V V D P P L PV+ T +
Sbjct: 8676 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8721
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
P+ + + II+ +D K+ T QPI E+E K
Sbjct: 8722 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8757
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342
+ +T L QE+ + ++ +NK G ++ + VD PP ++
Sbjct: 8758 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 8808
Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400
S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y
Sbjct: 8809 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 8868
Query: 1401 KFRVRAINVYGTSEPS 1416
+FRV+A+N G SEPS
Sbjct: 8869 EFRVKAVNEIGESEPS 8884
Score = 65.9 bits (159), Expect = 4e-10
Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15038
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A N G A+ V V D P P V S+ V P
Sbjct: 15039 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15085
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
A + I+Q E ++ W ++Q ++
Sbjct: 15086 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15116
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346
K+T L E+ + ++ NK G + + V+ PDPP P + I
Sbjct: 15117 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15172
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+
Sbjct: 15173 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15232
Query: 1405 RAINVYGTSEPSQES 1419
A N G S PS S
Sbjct: 15233 MAENAAGISAPSPTS 15247
Score = 65.9 bits (159), Expect = 4e-10
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW +
Sbjct: 15519 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15577
Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q
Sbjct: 15578 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15637
Query: 1418 ES 1419
S
Sbjct: 15638 LS 15639
Score = 65.9 bits (159), Expect = 4e-10
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T
Sbjct: 22845 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 22903
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K
Sbjct: 22904 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 22957
Score = 65.5 bits (158), Expect = 5e-10
Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
+AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G
Sbjct: 24429 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24488
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
L+I +V ++D Y ATN G+ T L VE L
Sbjct: 24489 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24530
Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
PK +G V G++ +G+P P +TW KG + + V
Sbjct: 24531 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24579
Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
L +GV + D G Y N G + EL + + R
Sbjct: 24580 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24633
Query: 269 SDVRKEVTNVISKESKLD 286
SDV ++ N+ E D
Sbjct: 24634 SDVSRDSVNLTWTEPASD 24651
Score = 64.7 bits (156), Expect = 8e-10
Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+ K + G+ L ++ V P I W +G+ LK T + + + + + I
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17874
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
++ +D G Y A N AG A + V V + P PPV
Sbjct: 17875 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 17916
Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
D + PP QI + +++ T TW
Sbjct: 17917 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 17960
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331
+ + +K+ + G++ + + EN+ G + V+ +P
Sbjct: 17961 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18008
Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389
PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F
Sbjct: 18009 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18067
Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
L EY+F+V A N+ G +PS+ SE + + P
Sbjct: 18068 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18109
Score = 64.7 bits (156), Expect = 8e-10
Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)
Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R
Sbjct: 26041 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26099
Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
GQ +++ R + + TF I +V D G Y+ N G ++ LT++ +
Sbjct: 26100 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26157
Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
K + P K+ R +P ET+P+ +
Sbjct: 26158 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26217
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
PPK L KE + + +C + +VTW K L+ + +G
Sbjct: 26218 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26275
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
L+I+ + + D G Y C + G + + + Q S + + ++ SD +
Sbjct: 26276 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26335
Query: 275 VTNVISK 281
+ V K
Sbjct: 26336 ESTVTRK 26342
Score = 64.3 bits (155), Expect = 1e-09
Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)
Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
VR G+++ + +V G TW K K + + + + +L I A + G Y
Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11482
Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
+ +N G Q + V+D+P P +++ + T+SW +GGS + ++ +
Sbjct: 11483 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11541
Query: 1369 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425
E K W +A+ + +LL ++EY FRV A N G P+ E++ +
Sbjct: 11542 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11600
Query: 1426 -EKPEEPKD 1433
++P EP++
Sbjct: 11601 IDRPGEPEN 11609
Score = 64.3 bits (155), Expect = 1e-09
Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)
Query: 1215 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269
G +S+ V + P P PP PP I+ D SV L K TG PIT
Sbjct: 13664 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13712
Query: 1270 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
++F R + K K+T L E+ + ++ N G + +
Sbjct: 13713 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13770
Query: 1328 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
V DP P G P +I +S+TL W YDGG + Y +E D +K+W +
Sbjct: 13771 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 13830
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431
+F V DL+ +Y+FR+RA N G S PS+ +E ++ E P
Sbjct: 13831 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 13879
Score = 63.9 bits (154), Expect = 1e-09
Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
QE C Y + EN+ G Q + V + P PP G D+ +S++LSW +
Sbjct: 16601 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16659
Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P
Sbjct: 16660 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16717
Score = 63.5 bits (153), Expect = 2e-09
Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271
S+ TV + P K P P + + +V+ E + G +V G + + W
Sbjct: 15832 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 15890
Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+K K K E G + + + G +G V P
Sbjct: 15891 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 15941
Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389
P G P A + +S+TL W +YDGGS + Y +E + W + + T F
Sbjct: 15942 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16001
Query: 1390 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432
V L+ DH Y+FRV A N G SEPS+ + T ++ + P+
Sbjct: 16002 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16045
Score = 63.5 bits (153), Expect = 2e-09
Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+
Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20449
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
+N G A + +V + D P P + T T+ +P P
Sbjct: 20450 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20496
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
A + I++ E +V W SEH++ E
Sbjct: 20497 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20526
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
T + E+ + + NK G + + +VV K P PP G P + I +
Sbjct: 20527 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20583
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404
S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV
Sbjct: 20584 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20643
Query: 1405 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439
A+N G S+ SE + P P ++ ++D
Sbjct: 20644 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20680
Score = 63.2 bits (152), Expect = 2e-09
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383
P P P D SS++L W + DGGS ++ Y +E+ + WK + T
Sbjct: 9207 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9266
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D
Sbjct: 9267 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9321
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383
+ KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ +
Sbjct: 10613 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10671
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432
C T + V L YKFRV A+N G S+P+ E V ++ E P+
Sbjct: 10672 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10720
Score = 63.2 bits (152), Expect = 2e-09
Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)
Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063
K V +S PLS P L+ K + TL L P+ G AK D + S
Sbjct: 12291 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12341
Query: 1064 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104
+EE D + + + + G + +K E++G A +Q L
Sbjct: 12342 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12401
Query: 1105 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
+ + + GKKL ++ V P T W + T+ + + + S + I
Sbjct: 12402 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12461
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215
+ +D G Y A+N +G +V V DAP PP +
Sbjct: 12462 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12506
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
++DA P + + I+ E V G+ V VT T +
Sbjct: 12507 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12557
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
K I E++ +EN G L K+ AQ V +P
Sbjct: 12558 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12602
Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388
T D + ++W DGGS + Y IE +W AN T RST
Sbjct: 12603 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12653
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
+ L+ EY FR+ A+N G+S PS+ +E T P +P + EV D
Sbjct: 12654 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12703
Score = 63.2 bits (152), Expect = 2e-09
Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)
Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G
Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25141
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C+ N G EL V+G +++ +T+ + +T + E PP+F
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25195
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
L G+ RF IT P+P VTW K ++P + + G+ L I
Sbjct: 25196 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25255
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ V DD YT + N G+ S A+L++
Sbjct: 25256 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 62.8 bits (151), Expect = 3e-09
Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)
Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143
D EK+ + P FK+KL + + +C+++ DP + W +GK L+
Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704
Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203
+ + E CS+ A D G+ C A N G S + V D E + E +
Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760
Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263
+ L + E A T K P I+ +PE +V GE+ +VTG
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323
W + I++S+ +V + L I+ + G + EN G + +V
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879
Query: 1324 NLTVVDKPD 1332
L + + D
Sbjct: 1880 KLEIQQRED 1888
Score = 62.8 bits (151), Expect = 3e-09
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386
KP PP P DI SS+ LSW YDGG +Q Y +E D + W
Sbjct: 16340 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16398
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
T+ V+ LL HEY FR+ AIN G E + V EK E P ++++
Sbjct: 16399 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16449
Score = 62.4 bits (150), Expect = 4e-09
Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G
Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14346
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
+ + N +GK S ++++ LD+ +R T T V +TN
Sbjct: 14347 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14404
Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
I ++ ++ A K C+ G S A N +P ++
Sbjct: 14405 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14464
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
++P ++ T S+++L P+P+ G ++ E +R + T T
Sbjct: 14465 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 14519
Query: 386 QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425
GL Q + +A R P E + + P+ + + Q++
Sbjct: 14520 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14579
Query: 426 -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
K +K V G PKP V W +G + +Q + A S L + + DSG
Sbjct: 14580 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 14638
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522
Y TA N G++ T+QV + P F V D
Sbjct: 14639 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 14677
Score = 62.4 bits (150), Expect = 4e-09
Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569
AP +KD G+ L C + G P+P I W G+ + +R + + L
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094
Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628
+ ED G YTC+A N +G+V S S+ LL P P P+ +
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24141
Query: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
+ GS + + V G P P + W H +Q SE+ E L ++ V +
Sbjct: 24142 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24197
Query: 689 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
G Y + N G V A+L V+ +P + P + A L S +IS
Sbjct: 24198 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24246
Score = 62.0 bits (149), Expect = 5e-09
Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I +D G +TC VN +G S S L++Q + F +ET A VT
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003
Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
+ E K ++S + + + Q G P A
Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035
Score = 62.0 bits (149), Expect = 5e-09
Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329
+++ + V + TI + H + ++ +NK G + + +
Sbjct: 9759 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9818
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383
P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A
Sbjct: 9819 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 9877
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
S+ V L+ +Y+FRV AIN G S S+ T + P
Sbjct: 9878 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 9925
Score = 62.0 bits (149), Expect = 5e-09
Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y AKN +G A+ S V V D P P +L T+ + T+
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11524
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
+ P D G IT +++RK Q+ +
Sbjct: 11525 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11555
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340
+ L A E+ + + ENK+G ++ + + +D+P P A
Sbjct: 11556 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11613
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
D + + L W YDGGS SY +E + W+ + + + T + V + +
Sbjct: 11614 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11672
Query: 1399 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
Y+FRV+ N G S+ + E+ V E ++P ++++S
Sbjct: 11673 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11711
Score = 61.6 bits (148), Expect = 7e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)
Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143
T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++
Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149
Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194
+SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA +
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209
Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238
+ E + R + + S ATV+ K P+ PPK + PP
Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269
Query: 1239 QI 1240
I
Sbjct: 270 SI 271
Score = 61.6 bits (148), Expect = 7e-09
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
II D ++T A N G ++ + L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505
Score = 61.6 bits (148), Expect = 7e-09
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 1308 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364
+ ++ EN G + + +D DPP G P +I ++TL W Y GG +
Sbjct: 14834 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 14892
Query: 1365 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421
SY +E D N W + F V L D Y+FRV A N G S PS+ S+
Sbjct: 14893 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 14952
Query: 1422 TTVGEKPEEPKDEVEVSDDD 1441
T + E PK +V+V D
Sbjct: 14953 ITCRDDVEAPKIKVDVKFKD 14972
Score = 61.6 bits (148), Expect = 7e-09
Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
PAFK V G+ L + P + W + LK T + + ++I
Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15710
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+ A ED G Y N AG+A + V V D P PP +
Sbjct: 15711 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15752
Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
D T PP K G S+ + V T TW
Sbjct: 15753 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15794
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331
S ++ TI A R + GC + + EN+ G S TV P
Sbjct: 15795 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 15841
Query: 1332 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387
P GTP + S+ + W DGGS V Y +E + + W +L T
Sbjct: 15842 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 15901
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
F L EY+FRV A N+ G +PS+ SE V P +P E +
Sbjct: 15902 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 15960
Query: 1448 DYRTVTINTEQKVSDFYDIEERLGSGKF 1475
++ T + K++ + ++ L G++
Sbjct: 15961 QWKKPTYDGGSKITGYIVEKKELPEGRW 15988
Score = 61.6 bits (148), Expect = 7e-09
Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P +K + VH E K+ + P TI W + L T + + S+S+
Sbjct: 16050 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16106
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
+ A+ D G Y AKN AG+ + V V D P PE P V+
Sbjct: 16107 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16149
Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275
S T +K PP II + +++ E+ L V Q ++C
Sbjct: 16150 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16199
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330
KV G++ T + ++ NK G + + VV K
Sbjct: 16200 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16239
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388
PD P P + + S+ + W + DGGS + Y +E D W
Sbjct: 16240 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16298
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
V L+ +H+Y+FRV A N G SEPS S
Sbjct: 16299 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16329
Score = 61.6 bits (148), Expect = 7e-09
Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
W+K K + K + G + + + G +G V
Sbjct: 18054 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18104
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388
P P G P A I +++TL W +YDGGS + Y +E D + W + T
Sbjct: 18105 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18164
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
F V L+ D Y+FRV A N G SEPS S T ++ + P ++
Sbjct: 18165 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18213
Score = 61.6 bits (148), Expect = 7e-09
Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)
Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W +
Sbjct: 21648 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21703
Query: 1381 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435
+ + R T F V L +EY+F V A N G S S L E P P V
Sbjct: 21704 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21763
Query: 1436 EVSDDDEKEPEVDY 1449
+V+D + +++
Sbjct: 21764 KVTDTSKTTVSLEW 21777
Score = 61.2 bits (147), Expect = 9e-09
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC
Sbjct: 18505 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18561
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
+ F V L + EY FR+ AIN G EP+ E+ E P+ E++
Sbjct: 18562 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18613
Score = 61.2 bits (147), Expect = 9e-09
Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+HV G+ + L ++ PP W G L+ ++ + + + ++I + D G
Sbjct: 23251 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23310
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223
Y KN G + +V + D P P+ E DAT +
Sbjct: 23311 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23355
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
+P P+ A + +++ + + G + ++ +T + KF + + +E+
Sbjct: 23356 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23405
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
+ + A + G Y +++++ ++ + + P PP T D+
Sbjct: 23406 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23446
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396
+TL+WY DGGS V Y +E W NK + RST L
Sbjct: 23447 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23501
Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432
EY+ RV AIN G+ +PS+ S+ + KP+ P+
Sbjct: 23502 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23543
Score = 60.8 bits (146), Expect = 1e-08
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
D L I++ +D+ YT A N++G+ + TA L +E E E E+E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3401
Score = 60.5 bits (145), Expect = 2e-08
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T
Sbjct: 13092 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13150
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
F V L+ D +Y+FRV A+N G S+PS
Sbjct: 13151 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13179
Score = 60.5 bits (145), Expect = 2e-08
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 1325 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
+ ++P PP D SS L+W +DGGS + Y +E+ + W E
Sbjct: 22043 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22101
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
+ +F V+ L+ EY+FRV+A N G SEP + + E EP
Sbjct: 22102 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22148
Score = 60.5 bits (145), Expect = 2e-08
Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P + + K + + C++ G P P++ W+ G + Q ++ D +H L
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 24094
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
++ D G Y+C A+N G++ S L ++ A + P + K + G L
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 24151
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589
G PVP +TW + +Q + + T E H+ ++ + H G Y N
Sbjct: 24152 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24211
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G V V + +K P KPT PI ++ L + + +S
Sbjct: 24212 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 24248
Query: 650 PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702
PP + W+ N E +E ++ + C E+ G Y A N+ G
Sbjct: 24249 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 24308
Query: 703 ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
+ +V+ ++ P + +P KP ++TA SC +A P
Sbjct: 24309 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 24350
Score = 60.5 bits (145), Expect = 2e-08
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G
Sbjct: 26350 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26408
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
F L IH D G YTC N +G+ + +LT++
Sbjct: 26409 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26445
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384
V KP PP G P D SS++++W YDGGS + Y +EI W+ + A
Sbjct: 15256 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15314
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
++TS+ + L + EYK R+ A+N G EP+
Sbjct: 15315 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15346
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
W K K + MKV + G Y + EN G + + V
Sbjct: 19136 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19184
Query: 1331 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386
DP P G P ++I S++L W YDGG+ + Y +E + + W + +
Sbjct: 19185 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19244
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D
Sbjct: 19245 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19300
Score = 59.7 bits (143), Expect = 3e-08
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
EK P F K + + ++ G A + G P P++ WF + + S ++ +D D
Sbjct: 3451 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3510
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
+ SLII +D+ +YTC A N G+ C+A L + + EG + E E
Sbjct: 3511 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3559
Score = 58.9 bits (141), Expect = 4e-08
Identities = 75/315 (23%), Positives = 117/315 (37%), Gaps = 29/315 (9%)
Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
++ + DS + +P ++ E++ + EVS +L+ TPV + S V
Sbjct: 4140 LQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVS 4199
Query: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524
++ L + + +S + S T A ++ + E + E P + L D
Sbjct: 4200 DEKQDESLKPSEEK-EESSSESGTEEVATVKIQ-----EAEGGLIKEDGPMIHTPLVDTV 4253
Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDH-GT 580
EG L S+ T + W + + + + + L I EDH G
Sbjct: 4254 SEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4311
Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
Y C A N G+ + SA +TV K AP+ + + L+V G
Sbjct: 4312 YVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIEPLEVALGHLA 4354
Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
T ++ P W G EI ES+ SL I D G YTC+A N
Sbjct: 4355 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4414
Query: 701 AGEVRTQAVLTVQEP 715
G V A LTV P
Sbjct: 4415 YGSVSCTATLTVTVP 4429
Score = 58.9 bits (141), Expect = 4e-08
Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)
Query: 1131 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189
W T+K TK + EGSL +++ A+N GQ++ + ++D
Sbjct: 7633 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7676
Query: 1190 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249
+ +++T + PP D T + PPK I ++ ++K
Sbjct: 7677 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7727
Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
R G W+K K + +V + G+++ + G
Sbjct: 7728 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7768
Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
+G + ++ P P P +D + ++W +GGS + Y
Sbjct: 7769 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 7822
Query: 1367 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
+E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE
Sbjct: 7823 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 7882
Query: 1424 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456
+ +P ++E D E E V +R V + T
Sbjct: 7883 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 7920
Score = 58.9 bits (141), Expect = 4e-08
Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G+ L+ V P TI W K ++ + + + ++ A+ D G Y
Sbjct: 17140 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17199
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
A N AG V V D P P V G S+ K
Sbjct: 17200 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17242
Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
+PP I + +++ E+ L V ++ +T
Sbjct: 17243 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17278
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343
N K+T L E+ + ++ NK G + + V+ K P PP ++I
Sbjct: 17279 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17333
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401
S+T+ W DGGS + Y +E D + W + R T V L DHEY+
Sbjct: 17334 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17393
Query: 1402 FRVRAINVYGTSEPS 1416
FRV A N G EPS
Sbjct: 17394 FRVSAENAAGVGEPS 17408
Score = 58.5 bits (140), Expect = 6e-08
Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V E + +F C ++ + V W +G + + ++ D H L + ++ D G
Sbjct: 5000 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 5056
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+ + +G+ + + RL V + F S L+D V EG+ C + +
Sbjct: 5057 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 5106
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
+ W N + +R+ + + H + + E L +S V E
Sbjct: 5107 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 5154
Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
S+ + + L P F L D ++ ++T+ +VS + P V W +G EI
Sbjct: 5155 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 5205
Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
S + + G + L I++ +D G Y C+ G +T+A +TV+ + +
Sbjct: 5206 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 5256
Query: 725 SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781
KP V +G++ ++ P VH W G+ L + E++++ L+L
Sbjct: 5257 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 5312
Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827
Q G+ N + +V + S + + REP +
Sbjct: 5313 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 5372
Query: 828 CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884
L G + G DR+ ++ G + ++ ED + + +HT
Sbjct: 5373 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 5425
Query: 885 --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938
E IR + + L +D+ K+ V T LS D+++ + + N QR ++V
Sbjct: 5426 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 5477
Query: 939 S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997
S ++E K HS + F+ L+ TS+ V + + KL G
Sbjct: 5478 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 5520
Query: 998 S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055
+ + + VE + + + S PV K + +KP NA
Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 5567
Query: 1056 DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112
+K+ K+ LKK +K+D+ GT + + + + L V V E
Sbjct: 5568 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 5624
Query: 1113 KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ + ++S D W L G+ L T + +EG + S+ + + G
Sbjct: 5625 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 5677
Score = 58.5 bits (140), Expect = 6e-08
Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)
Query: 1090 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147
R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + +
Sbjct: 18202 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18261
Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207
++ ++ + D G Y N G V V D P P
Sbjct: 18262 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18308
Query: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267
V G ++ P A + II+ E ++
Sbjct: 18309 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18350
Query: 1268 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+W + ++Q + K+T L E+ + ++ NK G + + V
Sbjct: 18351 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18396
Query: 1328 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381
KP P TP S I S+ ++W DGG+ ++ Y +E D W +
Sbjct: 18397 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18456
Query: 1382 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
T V L H Y+FRV A N G EPS+ S
Sbjct: 18457 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18494
Score = 58.5 bits (140), Expect = 6e-08
Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T +
Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24092
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + +ED G YTC ATN G + + +L ++ + G P+ K G
Sbjct: 24093 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24143
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
G R GRP P +TW G LQ S +++
Sbjct: 24144 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24181
Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
L + V + G Y + N G ++ IQ D V E N
Sbjct: 24182 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24241
Query: 269 SDV 271
S V
Sbjct: 24242 SAV 24244
Score = 58.5 bits (140), Expect = 6e-08
Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386
+KP P G P + + S ++W + DGG+ +++Y +E + W + T R
Sbjct: 24326 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24384
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE
Sbjct: 24385 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24435
Score = 58.5 bits (140), Expect = 6e-08
Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156
P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25357
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214
I LPED G Y+ A N AG C + V+ + K+ E R + + L
Sbjct: 25358 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25417
Query: 1215 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250
GTES +A V KPA T K +I + E++K+R
Sbjct: 25418 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25472
Score = 57.8 bits (138), Expect = 1e-07
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1816
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+IS DD +YT N GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 1e-07
Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
+ ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V
Sbjct: 17690 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17749
Query: 1366 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
Y +E+ + W +A + + V L EY+FRV+A N G S+P
Sbjct: 17750 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17799
Score = 57.8 bits (138), Expect = 1e-07
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 1739 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25276 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25335
Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25336 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25395
Query: 1856 GEGEEEEE 1863
E + +EE
Sbjct: 25396 QEFKSKEE 25403
Score = 57.4 bits (137), Expect = 1e-07
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1816
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 57.4 bits (137), Expect = 1e-07
Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
V KP PP D +S+TL+W YDGGS + Y +EI + + W+ +
Sbjct: 17420 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17478
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1442
R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E
Sbjct: 17479 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 17532
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Query: 1302 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358
QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D
Sbjct: 18766 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 18825
Query: 1359 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q
Sbjct: 18826 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 18884
Score = 56.6 bits (135), Expect = 2e-07
Identities = 92/417 (22%), Positives = 146/417 (35%), Gaps = 55/417 (13%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
PA LQD +EG+ QC+VS + W K +K ++F ++Q + I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS------ENTKAPEMK--------- 1202
+A PED G Y VA N GQ + +++ +AP S E EMK
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSL-EAPESILHERIEQEIEMEMKEFSSSFLSA 3416
Query: 1203 -------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
+ S + L S++ V P K P I+ + + G+
Sbjct: 3417 EEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEVSNADISMGDVA 3474
Query: 1256 ELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENK 1315
L V G W + S K + L IL + E G YT + N
Sbjct: 3475 TLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASND 3534
Query: 1316 LGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY-----------DGGSAVQ 1364
G L + K + T S + S L + G A+
Sbjct: 3535 YGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIF 3594
Query: 1365 SYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHEYKFRVRAINVY 1410
Y++ + TW K+L T S +F V D + + +A N+
Sbjct: 3595 EYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENML 3654
Query: 1411 GTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDF 1463
G S + E E T + + P + K E +D + P +++EQ+++ F
Sbjct: 3655 GESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDSEQEIATF 3711
Score = 56.6 bits (135), Expect = 2e-07
Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%)
Query: 921 EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 978
E+MD + Q+ V+P T E E K + S ++V + +V ++ K TPV + V +
Sbjct: 4142 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4200
Query: 979 P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 1033
S+ ++K + + S + E K E+ L + GP+ P+ + E
Sbjct: 4201 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4258
Query: 1034 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1083
+ NAK DE K + V + VN + H G
Sbjct: 4259 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4317
Query: 1084 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1138
T + K + + AP K+K++ + VA G C++ S P W G+ +
Sbjct: 4318 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4377
Query: 1139 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1198
+ + + S+ I + D G Y C A N+ G C+ +TV P E
Sbjct: 4378 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4436
Query: 1199 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
+ R+P+ VL + ++K+P PK PK + PE + E V
Sbjct: 4437 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4492
Query: 1256 EL 1257
E+
Sbjct: 4493 EV 4494
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y
Sbjct: 10039 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10096
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
+AKN+AG+ + + V V D P T P + S
Sbjct: 10097 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10136
Query: 1229 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
++ F PED G PIT ++ +++ V
Sbjct: 10137 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10170
Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341
+ T+ Q + + EN +G + +A V + P+ P
Sbjct: 10171 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10229
Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399
++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L
Sbjct: 10230 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10289
Query: 1400 YKFRVRAINVYGTSEPS 1416
Y++RV A+N+ G +PS
Sbjct: 10290 YEYRVSAVNIVGQGKPS 10306
Score = 56.6 bits (135), Expect = 2e-07
Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + ++ V P T+ W + LK T+ + + ++I + + D G Y
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A+N G+ + V D P PP + D
Sbjct: 14643 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14673
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
+ + F D G V Q + TW++ + + +
Sbjct: 14674 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14722
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
++LT Q + + +N+ G + +V P PP GTP + +
Sbjct: 14723 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14776
Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV
Sbjct: 14777 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 14836
Query: 1405 RAINVYGTSEPSQESE 1420
A N+ G S+PS+ SE
Sbjct: 14837 IAENMAGKSKPSKPSE 14852
Score = 56.6 bits (135), Expect = 2e-07
Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)
Query: 1057 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115
E L ++ E + KND A ++ K + + TA Q + G
Sbjct: 22109 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22168
Query: 1116 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
+ +S P + W L LK T + ++ +++++ ++ D G Y +N
Sbjct: 22169 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22228
Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
AG S V V P P + V +++ V PK
Sbjct: 22229 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22275
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
+ I++ E T W ++ ++ K+
Sbjct: 22276 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22305
Query: 1296 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351
T L E+ + + EN+ G S+ + + + P P P + + ++++++
Sbjct: 22306 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22363
Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N
Sbjct: 22364 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22423
Query: 1410 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
G S+ S+ S + + P + EV+D
Sbjct: 22424 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22452
Score = 56.2 bits (134), Expect = 3e-07
Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387
P P P +D S +L+W YDGG + Y +E ++ W + T R T
Sbjct: 14175 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14234
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+
Sbjct: 14235 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14285
Query: 1448 DYRTVTINTEQKVSDFYDIEER 1469
RT+ + + F I+ R
Sbjct: 14286 -RRTLVVRAGLSIRIFVPIKGR 14306
Score = 55.8 bits (133), Expect = 4e-07
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 1726 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1783
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1784 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878
Query: 1844 AELIVETMEE 1853
+L ++ E+
Sbjct: 1879 VKLEIQQRED 1888
Score = 55.8 bits (133), Expect = 4e-07
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 1306 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
GC + ++ EN+ G + V + P PP DI S+++L+W +DG
Sbjct: 14437 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14495
Query: 1360 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
GS + Y IE + W + T + V++L EY F+V A+N G S P +ES
Sbjct: 14496 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14554
Query: 1420 ELTTVGEKPEEPK 1432
V E+ P+
Sbjct: 14555 RPVIVKEQTMLPE 14567
Score = 55.5 bits (132), Expect = 5e-07
Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
AP F Q LQ V V EG + +S P + W +G+ + T+ + +S
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
++I + G Y A N +GQA + ++ V A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
PP +Q + VR G V L +VTG + +
Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140
Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
+IQ S ++ + L I A E G Y++ N +G + L V + + P
Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Query: 1335 A 1335
A
Sbjct: 201 A 201
Score = 55.5 bits (132), Expect = 5e-07
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1812
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24427 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24486
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
LII+ V DD Y +A N G + TA L VE
Sbjct: 24487 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26695
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26696 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26731
Score = 55.1 bits (131), Expect = 6e-07
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388
P PP P +D SS L W DGGS V Y +E + + W++ R T
Sbjct: 9925 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 9982
Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D
Sbjct: 9983 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10035
Score = 55.1 bits (131), Expect = 6e-07
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386
KP P P D + L W DGGS + Y +E W + R
Sbjct: 11305 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11364
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
+F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D
Sbjct: 11365 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11419
Score = 55.1 bits (131), Expect = 6e-07
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268
TES + K K P PP++ + +++ E G +TG + +
Sbjct: 11885 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 11942
Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
W+ K MKV+N +H + + EN++G + + V
Sbjct: 11943 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 11991
Query: 1329 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378
DP P G P D S+TL W YDGG+ + Y +E+ S ++ W
Sbjct: 11992 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12051
Query: 1379 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
K A F V L + EY+FRV A N G P++ E E E P+ ++
Sbjct: 12052 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12111
Query: 1436 EVS 1438
+ S
Sbjct: 12112 DAS 12114
Score = 55.1 bits (131), Expect = 6e-07
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399
D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L +
Sbjct: 23148 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23207
Query: 1400 YKFRVRAINVYGTSEPSQESELTTV 1424
Y FR+RA N G SEP + TV
Sbjct: 23208 YLFRIRAQNEKGVSEPRETVTAVTV 23232
Score = 55.1 bits (131), Expect = 6e-07
Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567
AP F L++ V + L C V G P P + W G+ I +Y + G +
Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I +D Y A N G VS +A + V P+K P L+
Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24535
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP
Sbjct: 24536 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24591
Query: 688 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734
+D G Y A N G + V V +P G + +S+ + AS
Sbjct: 24592 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24651
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA 760
G S + + + WLR G+A
Sbjct: 24652 GGSKITNYIVEKCATTAERWLRVGQA 24677
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383
PDPP I +++ LSW DGGS V Y +E WD + + W++
Sbjct: 9515 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9573
Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431
F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P
Sbjct: 9574 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9620
Score = 54.7 bits (130), Expect = 8e-07
Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101
+ G + K + G P P + W+++ + + + L C + T L + + DR
Sbjct: 20388 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 20443
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
G Y + N G+ T+ + + G P+ KT+ E +W
Sbjct: 20444 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 20495
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204
K+ +V++ + R + + +KGN + +P
Sbjct: 20496 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 20555
Query: 205 ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260
SV KN G+ + + + VV A +++S ++ D + +
Sbjct: 20556 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 20615
Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
+ K T D R++VT + + + C+ G P +P
Sbjct: 20616 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 20661
Query: 321 KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378
K D P + + T SSITL ++ + G V GEE +
Sbjct: 20662 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20721
Query: 379 PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421
T + PG+ VS A + P+E P+
Sbjct: 20722 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 20781
Query: 422 -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478
S K + V+ G P P V W + + GS Y E+ S L +
Sbjct: 20782 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 20837
Query: 479 TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528
TR D+G Y T N G+ S T+ V ++L V V+ ++L D +I+G
Sbjct: 20838 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 20896
Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
++ + + TW + + + D + + LAEN
Sbjct: 20897 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 20947
Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637
+G E PV ++ API + D DG
Sbjct: 20948 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 20993
Query: 638 SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697
V V E W H G I ++ + Q Q L + + G
Sbjct: 20994 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 21050
Query: 698 WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
+ G + + ++ E P VT +G +V + G P P++ WL+D
Sbjct: 21051 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 21103
Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817
G L K++ + E+ TL +K + H G+Y ++L N V C V + +
Sbjct: 21104 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 21160
Query: 818 ALPRG 822
+ P+G
Sbjct: 21161 SKPKG 21165
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)
Query: 1308 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
+ + EN G S T+ P P GTP D+ ++TL W DGGS +
Sbjct: 21332 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21391
Query: 1366 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419
YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S
Sbjct: 21392 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21447
Query: 1420 ELTTVGEKPEEP 1431
+ ++ P
Sbjct: 21448 GIIMTRDENVPP 21459
Score = 54.3 bits (129), Expect = 1e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 1746 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 1806 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 1e-06
Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%)
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
G+ + +V K + R+ + G R KF S + Q VKE +T F CE+S K V W
Sbjct: 5055 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 5109
Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
F + ++ + + +H L + + D +L
Sbjct: 5110 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 5159
Query: 508 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565
V+E P F+ L D +E + L+C V VP + W +G+ I S G+
Sbjct: 5160 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 5217
Query: 566 AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
L I+ A +D G Y C G A VTV + + KP
Sbjct: 5218 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 5259
Query: 625 FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684
L ++V G +++S P W G + S D + G +H L +
Sbjct: 5260 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 5314
Query: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744
TG + +A N+ ++ A L V+E FI+ V C +
Sbjct: 5315 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 5366
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782
+ +P T WL+ + + D FE++++ ++V+K
Sbjct: 5367 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 5402
Score = 54.3 bits (129), Expect = 1e-06
Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158
F+ KL + G+ L + S P + W + L+ + I + +L I
Sbjct: 10327 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10382
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
KA D G Y V +N G + CQV V D P PPV
Sbjct: 10383 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10424
Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
D K P I +K G+ V + + + TC K K +
Sbjct: 10425 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10480
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
+ +++ ++EN Y + S +A+ V D PD P T
Sbjct: 10481 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10525
Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395
D S ++W +DGG + +Y +E ++ +K W + T F V DLL
Sbjct: 10526 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10580
Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448
+Y+FRV A N G +PS S+ + +P V D VD
Sbjct: 10581 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10633
Score = 54.3 bits (129), Expect = 1e-06
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QL PV++K L PP F V G+ + GRP
Sbjct: 15636 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15678
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A
Sbjct: 15679 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15732
Score = 54.3 bits (129), Expect = 1e-06
Identities = 26/77 (33%), Positives = 44/77 (57%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y
Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16803
Query: 232 TCLVVNGSGKASMSAEL 248
V N G+ + S E+
Sbjct: 16804 GITVANVVGQKTASIEI 16820
Score = 54.3 bits (129), Expect = 1e-06
Identities = 25/72 (34%), Positives = 40/72 (55%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G+ + + GRP+P ++W+K PL+ + RV+V E VL I N+DD G Y
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885
Query: 232 TCLVVNGSGKAS 243
T N +G A+
Sbjct: 17886 TVTATNSAGTAT 17897
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1814
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25251
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 53.9 bits (128), Expect = 1e-06
Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 1736 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
+S + + A L V P +K + I LEV G A+F C+I+ P+ WFK
Sbjct: 4319 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4374
Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
+ I ES I + + SL I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4375 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4432
Score = 53.9 bits (128), Expect = 1e-06
Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16514
Query: 232 TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260
T + N SG + SA ++++ LD+ +
Sbjct: 16515 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 16572
Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311
V + +AT VTN K+D L+ A P + P A
Sbjct: 16573 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 16632
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363
PQPP + ++ + + T S I +Q + R L
Sbjct: 16633 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16691
Query: 364 LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411
+ + GEE K + PR P + ++D+V +
Sbjct: 16692 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 16732
Query: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
P + S V+ Q +K +SG PKP + W +G P+ +Q I V +
Sbjct: 16733 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 16789
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCS 499
L + + D G Y T +N GQ + S
Sbjct: 16790 LSIKETHKDDGGQYGITVANVVGQKTAS 16817
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26344 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26403
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26404 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26453
Score = 53.1 bits (126), Expect = 2e-06
Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R GRP P++TW + + +V + + L I +++D G
Sbjct: 17537 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17594
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D
Sbjct: 17595 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17646
Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328
AK KN +R + AN + + S K+E+ +
Sbjct: 17647 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17705
Query: 329 ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375
P + P L +TS+S+ + R G V + P G E K
Sbjct: 17706 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 17764
Query: 376 PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423
GL S KA N + +P+ + + P + +
Sbjct: 17765 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 17824
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
++ + +K V G P+P ++W +G P+ +Q + V E A S L + + D G
Sbjct: 17825 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 17883
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
Y+ TA+N+ G + + ++ V V P F V D VI
Sbjct: 17884 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 17927
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G
Sbjct: 21471 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21530
Query: 230 VYTCLVVNGSGKASMSAELSIQ 251
VYT N SG A ++ +Q
Sbjct: 21531 VYTVEAKNASGSAKAEIKVKVQ 21552
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24096 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24126
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
PT + + V G V + + ++G PPP W G++++ESE E
Sbjct: 23239 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23298
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734
L I+E DTG YT E N G T V+ + +P T P I + S+T S
Sbjct: 23299 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23358
Query: 735 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790
G + L + WL +++ + T F L + + + + G
Sbjct: 23359 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23418
Query: 791 QYEILLKNRVGECSCQVSL 809
Y L++ V EC + +
Sbjct: 23419 SY---LQSEVIECRSSIRI 23434
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
LVI +D G+YT N G + L E +
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131
Score = 52.4 bits (124), Expect = 4e-06
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 1730 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1789
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 15624 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15682
Query: 1790 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 15683 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15740
Score = 52.4 bits (124), Expect = 4e-06
Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280
K P TP PP+ P + SV L K G +T +++ ++ +
Sbjct: 23818 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 23877
Query: 1281 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332
H K + + +T L E+ + ++ +N +G S + + VV DKP
Sbjct: 23878 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 23935
Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390
P S I S+TL W DGG + Y +E S + WK+ + F
Sbjct: 23936 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 23994
Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438
+ LL EY+FRV A N G S P S +++LT+ GE P K+ +V+
Sbjct: 23995 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24046
Score = 52.4 bits (124), Expect = 4e-06
Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P F+ + ++ V+ C+V+G PKP V W+ +G + + E G ++
Sbjct: 24431 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24490
Query: 474 LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
++ + T D T Y A+N G +S + +L+VE A + + P + + G+
Sbjct: 24491 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 24549
Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587
++ G P P ITW GQ + + V P +D G Y A+N
Sbjct: 24550 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 24608
Query: 588 ALG 590
G
Sbjct: 24609 RFG 24611
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G
Sbjct: 25081 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25140
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
Y C VVN G+ S AEL ++G+ + R T
Sbjct: 25141 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25175
Score = 52.0 bits (123), Expect = 5e-06
Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
++ H+ G L L + P + W + T I ++ GS + I A ED
Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10786
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
G+Y +N AG S +V V D P P+ + +S K
Sbjct: 10787 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 10834
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+P G SV V + W ++ H
Sbjct: 10835 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 10872
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341
+E L +AA EN+ G + DP P G P
Sbjct: 10873 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 10920
Query: 1342 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
D+ + ++L W DGGS + Y +E + + W + T + V L
Sbjct: 10921 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 10980
Query: 1400 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
Y+FRV+A N+ G P + EK P E++V
Sbjct: 10981 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11017
Score = 52.0 bits (123), Expect = 5e-06
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R
Sbjct: 21471 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21529
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G YT EA N SG+ + +++ V+ + K +G + G++ +
Sbjct: 21530 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21573
Score = 51.6 bits (122), Expect = 7e-06
Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%)
Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469
++A P F + QS V++ V+ + V+GIP P V ++ +G + + ++ ++
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158
Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
+ L + +A DSGTYS A+N+ G+ + + L V+
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 51.6 bits (122), Expect = 7e-06
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327
W K K + + H KV G + + EN G +
Sbjct: 20219 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20267
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
+D +PP +DI +S++LSW ++DGGS + Y +E D + W +
Sbjct: 20268 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20326
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417
T F + L + +Y+FRV A N G+ S PS+
Sbjct: 20327 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20359
Score = 51.2 bits (121), Expect = 9e-06
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385
+ P PP P +D S+++ L W +++GG + Y ++ W +
Sbjct: 8503 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8560
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
+ V+++ +YK RV A+N G P E++ TV E E P E++VS
Sbjct: 8561 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8612
Score = 50.8 bits (120), Expect = 1e-05
Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)
Query: 1125 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183
PP T+ W + K L + + S ++I + D G Y +N G+ + S
Sbjct: 20802 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 20861
Query: 1184 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238
V V D PA+ + SR + L PP++ S + ++K+ A K
Sbjct: 20862 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 20913
Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298
TW + + ++ SE
Sbjct: 20914 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 20939
Query: 1299 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356
+ +L EN++G + V + PA S D +S+ LSW
Sbjct: 20940 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 20990
Query: 1357 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
+DGGS + Y +E +TW ++ V L +FRV A N G S+P
Sbjct: 20991 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21050
Query: 1417 QESELTTVGEKPEEPKDEVEVSD 1439
+ TV E P EV++SD
Sbjct: 21051 TIGPI-TVKELIITP--EVDLSD 21070
Score = 50.8 bits (120), Expect = 1e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343
SE K+T L E+ + ++ EN G A L +P P G P +D
Sbjct: 21711 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21768
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401
++++L W +DGG + Y IE+ + W ++ C T + V DL EYK
Sbjct: 21769 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 21828
Query: 1402 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
FRV AIN G + + + ++ P+ +++ +
Sbjct: 21829 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 21865
Score = 50.1 bits (118), Expect = 2e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
G P + + VT LG++ +SC I G P P + W R GK L + + +++ +
Sbjct: 24033 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24091
Query: 778 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
TL + + G Y + N VGE L+LQ
Sbjct: 24092 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24126
Score = 49.7 bits (117), Expect = 3e-05
Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)
Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
S P E + E P F L + VK G +TG+P+P++TW K ++ L+
Sbjct: 7176 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7235
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
R+++ + I + D G Y VN G+A+ E+++
Sbjct: 7236 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7295
Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
D N S + D ++TN + + DS
Sbjct: 7296 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7330
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
P PP G P S+ +SW +GGS + Y +E + + W ++
Sbjct: 9102 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9160
Query: 1385 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439
+ FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D
Sbjct: 9161 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9218
Score = 49.7 bits (117), Expect = 3e-05
Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + L V PP I W+ L+ + + + E D G Y
Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13270
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
+N G+ E + V V D P PPV T + + P
Sbjct: 13271 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13312
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
P II + ++ + K T C+ FR V N E
Sbjct: 13313 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13355
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348
G + + EN+ G V P G +RS SS
Sbjct: 13356 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13403
Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408
++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N
Sbjct: 13404 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13462
Query: 1409 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
G P SE+T V +D+V D D K
Sbjct: 13463 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13488
Score = 49.7 bits (117), Expect = 3e-05
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+
Sbjct: 16741 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16799
Query: 789 AGQYEILLKNRVGECSCQVSLM 810
GQY I + N VG+ + + ++
Sbjct: 16800 GGQYGITVANVVGQKTASIEIV 16821
Score = 49.7 bits (117), Expect = 3e-05
Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G
Sbjct: 18620 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18677
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
Y + N SG S +A ++++ LDS + +RE K + D ++TN
Sbjct: 18678 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18735
Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
I ++ + A + NC+ Q G S + + + E+ +
Sbjct: 18736 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18795
Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
+ P P + T +T A ++ E + G V + K + T
Sbjct: 18796 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 18855
Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431
GL G + V AA R P E KP + VK + +
Sbjct: 18856 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 18915
Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
K G P+ V W +G + ++ + V L + +A D GTY SN
Sbjct: 18916 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 18974
Query: 492 AQGQLSCSWTLQV 504
+ G ++ T+ V
Sbjct: 18975 SAGSITVPITIIV 18987
Score = 49.3 bits (116), Expect = 4e-05
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12867
Query: 230 VYTCLVVNGSGKASMSAELSI 250
YT N SG S + +L +
Sbjct: 12868 DYTITAENSSGSKSATIKLKV 12888
Score = 48.9 bits (115), Expect = 5e-05
Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)
Query: 1131 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D
Sbjct: 13916 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 13975
Query: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
P PP S+ + +K TPP I + +++
Sbjct: 13976 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14015
Query: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310
E+ L W + IQ H+ + + G++ + H G
Sbjct: 14016 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14056
Query: 1311 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
G + +VD+ P P P S++ ++ T+SW DGGS + Y +
Sbjct: 14057 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14111
Query: 1369 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426
E + + W + V L Y+FRV A N G PS+ S+ + +
Sbjct: 14112 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14171
Query: 1427 K--PEEPKDEVEVSDDDEK 1443
P P V+D +K
Sbjct: 14172 AAYPPGPPSNPHVTDTTKK 14190
Score = 48.5 bits (114), Expect = 6e-05
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)
Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
I++T++++ P S P+T A +PPR L +K G + V G P P
Sbjct: 12770 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 12828
Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++
Sbjct: 12829 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 12885
Query: 121 LTV 123
L V
Sbjct: 12886 LKV 12888
Score = 48.5 bits (114), Expect = 6e-05
Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)
Query: 1325 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
+ +D PP P +D +S++L+W +GGS V Y IE+ W +
Sbjct: 23527 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23584
Query: 1383 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
C +T +++ H EY+FRV A N G EP++ V E E P E++
Sbjct: 23585 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23642
Score = 48.1 bits (113), Expect = 8e-05
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566
+ + PS ++ G+D ++ V G P P I+W+ +G+P+ Q R E A
Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17870
Query: 567 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
LHI++ +D G YT A N+ G + + V V EK
Sbjct: 17871 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 17907
Score = 48.1 bits (113), Expect = 8e-05
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QLG PV+++ +E +PS+ E P F T VK + + GRP
Sbjct: 18883 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 18925
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ +
Sbjct: 18926 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 18983
Query: 249 SIQGLD 254
+I LD
Sbjct: 18984 TIIVLD 18989
Score = 48.1 bits (113), Expect = 8e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)
Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
C TN ELT + + + V ++ D S P+ T P I + PP+
Sbjct: 19237 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19292
Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
+ +VVK G++ + + I GRP P ++W K + ++ AR + + +L +
Sbjct: 19293 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19352
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ D G Y + N +G S++ +
Sbjct: 19353 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19382
Score = 48.1 bits (113), Expect = 8e-05
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)
Query: 1700 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1759
AV + + S M S + KS L++ + + ++ A LE + E+
Sbjct: 25998 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26057
Query: 1760 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
T+ R + V EG +ARF C +G P P V W + Q + S Q+ +
Sbjct: 26058 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26116
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ IS V D+ Y+ NS G+ L ++
Sbjct: 26117 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154
Score = 47.8 bits (112), Expect = 1e-04
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1808
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.8 bits (112), Expect = 1e-04
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 1263 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322
G P+T ++ ++++ KV + + T+ Q + + NK G +
Sbjct: 7018 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076
Query: 1323 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376
VN+ T PDPP D ++S+ L+W DGGS ++ Y +E +
Sbjct: 7077 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7135
Query: 1377 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
W T V L Y +RV+A+N G S+PS+ +E + E P+ +
Sbjct: 7136 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7195
Query: 1436 EV 1437
+V
Sbjct: 7196 DV 7197
Score = 47.8 bits (112), Expect = 1e-04
Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%)
Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478
K ++ + G P P+ +W +G + ++G ++ EDA S + + + +
Sbjct: 9326 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9385
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531
+G YS TA N GQ + + ++V + L V ++ + +G D
Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 9444
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
++G + + T ++G+ C G + D L E + AEN G
Sbjct: 9445 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 9495
Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
V ++ ++R P+ P P +K+ G TV +S PP
Sbjct: 9496 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 9538
Query: 652 PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
+ W G + + + ++ + ++++ + +A
Sbjct: 9539 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 9597
Query: 699 NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756
N+AG + A + + P I + G +V I I G PFPT+ W +
Sbjct: 9598 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 9657
Query: 757 ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
D K H L +D TLV+ + + G Y I N +G S ++ L
Sbjct: 9658 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9714
Score = 47.8 bits (112), Expect = 1e-04
Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)
Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630
P D + +A NA+G +S S+ S ++ V P P + GL
Sbjct: 21423 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21472
Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
+ G + + V G P P V W +G EI++ + SL +++ +
Sbjct: 21473 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21529
Query: 691 GTYTCEAWNSAGEVRTQAVLTVQE 714
G YT EA N++G + + + VQ+
Sbjct: 21530 GVYTVEAKNASGSAKAEIKVKVQD 21553
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
+++P PP +SD SS+ L W DGGS + Y IE + W +
Sbjct: 6792 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 6850
Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
++ V L ++Y +RV A N G S+PS+ T + EP ++ D
Sbjct: 6851 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 6905
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)
Query: 574 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632
+P++ T T L E A Q A V+ S S+ + +A + P + + S L
Sbjct: 12749 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 12808
Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689
V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D
Sbjct: 12809 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 12865
Query: 690 TGTYTCEAWNSAG 702
+G YT A NS+G
Sbjct: 12866 SGDYTITAENSSG 12878
Score = 47.4 bits (111), Expect = 1e-04
Identities = 25/82 (30%), Positives = 36/82 (43%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
+ KE R I G+P P V+W KG PL RVSV L ++ + D G
Sbjct: 13496 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13555
Query: 231 YTCLVVNGSGKASMSAELSIQG 252
YT + N +G + + + G
Sbjct: 13556 YTITLKNVAGTKEGTISIKVVG 13577
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T
Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17870
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
L I +++D GKYT ATN +G + + V
Sbjct: 17871 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 1731 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 21435 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21494
Query: 1791 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21495 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552
Score = 47.4 bits (111), Expect = 1e-04
Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
I+ G+ + V G PEP++ W + + + + L G R T VI D G
Sbjct: 22562 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22619
Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
KYT N SG + V+V + V S G+ VS+ ++ +S P + I
Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22678
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
+ T V+ EG+ S +T + +V + P P + +N
Sbjct: 22679 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22738
Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
+ G+ ++ G ++ ++ E+S +D + +R T+
Sbjct: 22739 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22798
Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
D R +VT+++ + C R + A NS+P S SC++
Sbjct: 22799 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 22841
Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
P +AP+ V+ T SI+L + + +G + E+ A
Sbjct: 22842 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 22899
Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420
R F +G + AA + ++G + + E +P
Sbjct: 22900 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 22956
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479
++ ++ +++ VSG P P + W +G + S + + S+ L ++ K
Sbjct: 22957 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 23012
Query: 480 RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
D+G Y+ A N G+ S + ++V + V EV+ ++ + I+G
Sbjct: 23013 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 23068
Query: 533 LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590
G PV I + T + I + + L EN G
Sbjct: 23069 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23122
Query: 591 --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
S V V E +P+ P+K L+V+D ++ T+T ++
Sbjct: 23123 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 23158
Query: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705
P L++G + GT+ + + + P E T T E +R
Sbjct: 23159 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23213
Query: 706 TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752
Q V EP + + R ++ G+ V + IAG P P
Sbjct: 23214 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 23273
Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
W G L +++ V + V L +++ G+Y + LKN G S + +++
Sbjct: 23274 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 23332
Query: 813 NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
+ A ++ EP + GG G ++ + RPGW
Sbjct: 23333 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 23382
Score = 47.4 bits (111), Expect = 1e-04
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387
P PP G P + + W DGG+ + +Y ++ + + W + T
Sbjct: 22743 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22801
Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
V L+ +Y+FRV A+N G SEPS+ S + E P
Sbjct: 22802 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 22845
Score = 47.4 bits (111), Expect = 1e-04
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
V + S S++ ++P +P E + + + I+ GA+ + V G P P
Sbjct: 22923 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 22980
Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V
Sbjct: 22981 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23037
Score = 47.0 bits (110), Expect = 2e-04
Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%)
Query: 988 KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 1045
++++ + +GS E + VES +S + S V K + +A ++
Sbjct: 4141 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4200
Query: 1046 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1105
K + KP E + +S E ++V V + G + P L
Sbjct: 4201 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4250
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1164
D EG + L +++ + W K + + + Q+ + ++ I+K ED
Sbjct: 4251 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4308
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
+G Y C A ND+G+ S ++TV K
Sbjct: 4309 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4333
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+ AP K E +V G + ++ + W K ++I ES+
Sbjct: 4334 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4383
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+ +S+ S L IL + CG YT N+ GS LTV
Sbjct: 4384 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426
Score = 47.0 bits (110), Expect = 2e-04
Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%)
Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 810
V+W + K + D F+ LQ+++ +TLV+ KV H G+Y N G+ + L
Sbjct: 4272 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4330
Query: 811 LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 870
+ +A + R EP ++ G + ++R W G+ + E D +R
Sbjct: 4331 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4386
Query: 871 G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 917
+L+ +V + ++T +A + L G+K K L E K
Sbjct: 4387 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4444
Query: 918 IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 963
P E++ ++ L++ + +PK ++ KV P ++V+ +V ++
Sbjct: 4445 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4502
Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 1023
K P P KVP KPA P LPA E A+ P +P+
Sbjct: 4503 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4548
Query: 1024 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1083
PV P K A E KP G P + + + ++ + + G
Sbjct: 4549 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4603
Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1137
+ + + F ++++D+ + E G + +C VS P+T I W +G
Sbjct: 4604 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4660
Query: 1138 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
++ + +FI ++ L + ++ + D G Y CV + + + ++ V++ P
Sbjct: 4661 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4714
Score = 47.0 bits (110), Expect = 2e-04
Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)
Query: 1111 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169
EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25143
Query: 1170 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228
C ND G+ ++ V + + RR T+KK K
Sbjct: 25144 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25183
Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285
T PP+ ++ GE+V +T TW K ++I+ ++ K
Sbjct: 25184 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25243
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334
E+ + +LTI + + YT++ NK G + LTV P P
Sbjct: 25244 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25303
Query: 1335 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
G +IR S + TL W DG +IEI +
Sbjct: 25304 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25354
Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
+ +++D LP+ +RV A N G++ ++ + K +E K + E +K+
Sbjct: 25355 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25411
Query: 1445 PEVDYRTVTI 1454
+ R I
Sbjct: 25412 IDKTLRMAEI 25421
Score = 46.2 bits (108), Expect = 3e-04
Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+ + + +G A FE V G P P VTW + + + + + + G+ + +
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144
++ ED G Y C+A N G EL V P +K+ +
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3694
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PAVE S + AT + ++K + + +++ + L +PL
Sbjct: 3695 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3749
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260
S+ E++ + + + C +NGS S L +Q + S ++F
Sbjct: 3750 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3798
Query: 261 VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ ET+A SD K + +S E +++SL + P+ G P
Sbjct: 3799 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 3852
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353
S +PP S L S + +P+ + T+ +TLQ Q
Sbjct: 3853 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 3895
Score = 46.2 bits (108), Expect = 3e-04
Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444
GLG D IP+E Q P E + E VK TV+F + G+P P
Sbjct: 10992 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 11044
Query: 445 VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504
W +G+ ++ E V D S L + RD+G Y T SNA G + + L V
Sbjct: 11045 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
LP KE + + + ++G P P V+W + P+ + R ++ T +L+++
Sbjct: 13490 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13548
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125
+ D GKYT N +G ++ T+ + V G
Sbjct: 13549 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13577
Score = 46.2 bits (108), Expect = 3e-04
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 1717 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1771
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 26184 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26243
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 26244 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26294
Query: 1832 K 1832
+
Sbjct: 26295 E 26295
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I +
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188
D G YK + G+ E +C ++V+
Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 5875 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 5930
Query: 1814 CSLIISDVCGDDDAKYTCK 1832
L+I+ DD+A+Y+C+
Sbjct: 5931 RILVINKCLLDDEAEYSCE 5949
Score = 45.8 bits (107), Expect = 4e-04
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565
++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G
Sbjct: 21460 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21516
Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
L ++DA + G YT A+NA G V V +
Sbjct: 21517 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21553
Score = 45.4 bits (106), Expect = 5e-04
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 45.4 bits (106), Expect = 5e-04
Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%)
Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
RQ TV+ EG+ K V + G P ET+P E A +L G
Sbjct: 8562 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8616
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ + G+ R +TGRP P W K L RV + L I + D G
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8675
Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
Y N G +A L ++ + + + + D E+T I
Sbjct: 8676 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8735
Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
K++K+ + +E + + G + ++ + PP E D
Sbjct: 8736 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8795
Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
P T+P+ ++T S+ITL EPR+ G + E++R P
Sbjct: 8796 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 8851
Query: 382 FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423
PT + + D KA N +P+ Q D P + + +
Sbjct: 8852 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 8911
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478
+VK + V +V+G+P P++ W T + + ++++ ++ S L + KA
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971
Query: 479 TRDSGTYSCTASNAQGQL 496
D GTY+ TASN G +
Sbjct: 8972 REDKGTYTVTASNRLGSV 8989
Score = 45.4 bits (106), Expect = 5e-04
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%)
Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567
+V P+FSS +V GQD ++ + G P P ITW +G P++ T +
Sbjct: 16734 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16789
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
L I++ +D G Y N +GQ + S + +K P P P+
Sbjct: 16790 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 16836
Query: 628 GLSDLKVMDGSQVTMTVQVSGNPP 651
+S ++ +S NPP
Sbjct: 16837 DVS----------AESITLSWNPP 16850
Score = 45.4 bits (106), Expect = 5e-04
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
+ G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885
Query: 694 TCEAWNSAG-EVRTQAVLTVQEP 715
T A NSAG +V+ +++P
Sbjct: 17886 TVTATNSAGTATENLSVIVLEKP 17908
Score = 45.1 bits (105), Expect = 7e-04
Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+K G + E V G P P + W ++G+ + + + T +LV D G
Sbjct: 14976 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15034
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160
YT ATN G FAK + V G + V + + P
Sbjct: 15035 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15081
Query: 161 P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215
P K+ +V++ + R + + QVT LK L+ + RV K G+
Sbjct: 15082 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15140
Query: 216 -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256
VL ++ D + C S S ++ D A
Sbjct: 15141 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 15200
Query: 257 NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315
+ +++ K T +D+R +V+ + E + + A + SP +P
Sbjct: 15201 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 15260
Query: 316 PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366
PP + L++ + S A P+ S PE P A GL S
Sbjct: 15261 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 15319
Query: 367 SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423
+ + + GLG +V KA +R +P E + D+ K +
Sbjct: 15320 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 15374
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481
++ T++ + G P PEV W + E + ++ S Y L+ D
Sbjct: 15375 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 15428
Query: 482 SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
SG Y T N+ G S ++V + L V EV + ++ D +++G +
Sbjct: 15429 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15488
Query: 535 CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593
V R + + C ++ D L E Y LAEN G +
Sbjct: 15489 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 15537
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
A K S R P+ P K T +MD ++ +V +S P
Sbjct: 15538 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 15576
Query: 654 VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
H+G + +G+ + + C E T T + + V Q +
Sbjct: 15577 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 15632
Query: 713 QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
+P + P I+K + T G+ + + G P P V W +D L
Sbjct: 15633 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15691
Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
K T E+ L +K G Y + L N GE
Sbjct: 15692 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 15731
Score = 45.1 bits (105), Expect = 7e-04
Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)
Query: 1228 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284
P PP A P++ + +R E G I W+ K R I +
Sbjct: 22340 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22394
Query: 1285 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
KV E K+T L E+ Y L + +A + + D P G P +D+
Sbjct: 22395 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22453
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398
S+++L W +YDGGS V Y IE + + + W + F V L
Sbjct: 22454 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22513
Query: 1399 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
Y+FRV A N G S+ S+ + T ++ PK E++
Sbjct: 22514 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22552
Score = 44.7 bits (104), Expect = 9e-04
Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%)
Query: 656 WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
W+ +G+ I+ES F G L I +V D G YTC E + A L V+E
Sbjct: 4654 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713
Query: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
+ + VT GQ + +SC + + V W +DGK + + G
Sbjct: 4714 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 4768
Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810
+ L + AG Y + ++N ECS V ++
Sbjct: 4769 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 4804
Score = 44.7 bits (104), Expect = 9e-04
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386
P P G P D+ S+++L W +DGGS + Y +E W T
Sbjct: 12692 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12751
Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
+ L +Y+FR A S PS+ S+ T+ + P+ ++ V+
Sbjct: 12752 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12803
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
L +K G T +F +RG P P W +G I + + ++ FS L I
Sbjct: 11023 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11079
Query: 100 DRGKYTCEATNGSGARQVTVELTV 123
D G+Y +N +G++ V V LTV
Sbjct: 11080 DTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)
Query: 601 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
+EK S + +PV A P F + V+ G + + V G P P V W +
Sbjct: 15628 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15687
Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718
++++ + E L I++ ED G Y + NSAGE + T V+ + +P
Sbjct: 15688 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15747
Query: 719 TQP 721
T P
Sbjct: 15748 TGP 15750
Score = 43.9 bits (102), Expect = 0.001
Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+V+ G R + GRP P+VTW K + + V + M L I +DD G
Sbjct: 12119 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12177
Query: 230 VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279
Y+ +VN +G+ ++ + + + S V +T +D +VT+ I
Sbjct: 12178 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 12237
Query: 280 SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311
++ + D A P P A++
Sbjct: 12238 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 12297
Query: 312 --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365
S+P PPR+ ++ + T P L+ K IT QP R V+
Sbjct: 12298 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 12357
Query: 366 ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413
G++ K R A + P G V +A + +P
Sbjct: 12358 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 12402
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
PK P+ +K + ++ V G P P W +G + V++ S L
Sbjct: 12403 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 12460
Query: 474 LLKARTRDSGTYSCTASNAQG 494
+ +DSG YS TA N+ G
Sbjct: 12461 IKDVTRKDSGYYSLTAENSSG 12481
Score = 43.9 bits (102), Expect = 0.001
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L
Sbjct: 12402 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12460
Query: 220 IHGVNQDDVGVYTCLVVNGSG 240
I V + D G Y+ N SG
Sbjct: 12461 IKDVTRKDSGYYSLTAENSSG 12481
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)
Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
VK V ++ +SK S +V P R D P + F+ ++EG +++G P
Sbjct: 9594 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9647
Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
P +TW + N +P+ T + ++D T +LVI D G YT A N
Sbjct: 9648 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9703
Query: 111 GSGARQVTVELTVEG 125
G + L V G
Sbjct: 9704 NLGTASKEMRLNVLG 9718
Score = 43.1 bits (100), Expect = 0.003
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 0.003
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1819
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9629 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9687
Query: 1820 DVCGDDDAKYTCKAVNSLGEAT 1841
D YT AVN+LG A+
Sbjct: 9688 QSRRSDTGLYTITAVNNLGTAS 9709
Score = 43.1 bits (100), Expect = 0.003
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
Y N SG A SA +++ LD + K TN V KE IS E+ LD+
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11531
Score = 43.1 bits (100), Expect = 0.003
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12391 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12450
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12451 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12491
Score = 43.1 bits (100), Expect = 0.003
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 1731 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1787
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 16020 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16076
Query: 1788 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 16077 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16135
Query: 1848 V 1848
V
Sbjct: 16136 V 16136
Score = 43.1 bits (100), Expect = 0.003
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390
P PP S + S+TL W DGGS + Y IE + + W +
Sbjct: 19486 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19544
Query: 1391 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421
V+ L EY++RV A N G S PS+ S L
Sbjct: 19545 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19577
Score = 42.7 bits (99), Expect = 0.003
Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)
Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150
+G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
+++++ ED+G Y V
Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293
Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
+ G ++ +K KP P I+Q DQKV G+ V+L KV+ + +
Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341
Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401
Query: 1331 PDP 1333
P
Sbjct: 2402 ITP 2404
Score = 42.7 bits (99), Expect = 0.003
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 1760 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1813
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4620 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4677
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
+I DV D +YTC E T TA+L+VE +
Sbjct: 4678 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)
Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
+ + TV G Q + V++K S P+ T P + PKF
Sbjct: 17079 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17137
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
+VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D
Sbjct: 17138 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17195
Query: 228 VGVYTCLVVNGSGKASMSAELSI 250
G Y N +G S + +
Sbjct: 17196 GGQYILRASNVAGSKSFPVNVKV 17218
Score = 42.4 bits (98), Expect = 0.004
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107
+KS K +++ K + + +N + H G + + T+ A F++ ++D+
Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021
Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167
V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G
Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080
Query: 1168 YKCVAKNDAGQAE 1180
Y VA + A+
Sbjct: 3081 YTVVAGGNVSTAK 3093
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
+K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y
Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10790
Query: 232 TCLVVNGSGKASMSAELSI 250
+ V N +G ++S ++ +
Sbjct: 10791 SLTVENPAGSKTVSVKVLV 10809
Score = 42.4 bits (98), Expect = 0.004
Identities = 21/72 (29%), Positives = 34/72 (47%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++++ G R + GRP P++TW K NV L+ + + + L VN+ D G
Sbjct: 13206 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13265
Query: 230 VYTCLVVNGSGK 241
Y + N GK
Sbjct: 13266 KYILTLENSCGK 13277
Score = 42.4 bits (98), Expect = 0.004
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + + V G P P V W +++++ +FE T L I E D+G Y
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642
Query: 697 AWNSAGEVRTQAVLTVQ 713
A N GEV V+T+Q
Sbjct: 14643 ARNIVGEVGD--VITIQ 14657
Score = 42.4 bits (98), Expect = 0.004
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576
KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+
Sbjct: 16053 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16112
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633
D G Y A+N G+ S VTV+ K R P P P+ + G++ K
Sbjct: 16113 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16159
Query: 634 -----VMDGSQVTMTVQVSGNPPPEVIW 656
+ DG + V ++W
Sbjct: 16160 AWKPPLQDGGSDIINYIVERRETSRLVW 16187
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16732 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16786
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
+L I + DD +Y N +G+ T + E++
Sbjct: 16787 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16821
Score = 42.4 bits (98), Expect = 0.004
Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 736 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795
+ + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+
Sbjct: 18913 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 18971
Query: 796 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
+ N G + +++++ + P + SC+ +
Sbjct: 18972 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19007
Score = 42.0 bits (97), Expect = 0.006
Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158
F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 5847
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
PED Y C DA + SC + V
Sbjct: 5848 DCTPEDIKTYTC----DAKDFKTSCNLNV 5872
Score = 42.0 bits (97), Expect = 0.006
Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E F N+ + E T K V P +V W++ + I GR+ + R
Sbjct: 5962 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6020
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
LVI H ED G Y C + +V V
Sbjct: 6021 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6051
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
E +F +K + + EG+ F C I+ P V W + + L+ +
Sbjct: 6052 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6101
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V +VL + D+G Y +V G A +A L++
Sbjct: 6102 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6139
Score = 42.0 bits (97), Expect = 0.006
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578
G+ + V G P+P+I W N I+ + EL I A+ ED
Sbjct: 8916 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 8975
Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKS 605
GTYT A N LG V + V V+++ S
Sbjct: 8976 GTYTVTASNRLGSVFRNVHVEVYDRPS 9002
Score = 42.0 bits (97), Expect = 0.006
Identities = 26/93 (27%), Positives = 39/93 (41%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
P+ + ++ + L V G+ V + G P P W +G+EI+ E + E
Sbjct: 11011 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11070
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
L I+ DTG Y N+AG LTV
Sbjct: 11071 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 42.0 bits (97), Expect = 0.006
Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%)
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
V G P P+V W G ++G +++ + +L + + DSG YS T N G+
Sbjct: 12133 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 12190
Query: 497 SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
+ ++V L V +V + V +G V V R TW
Sbjct: 12191 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 12248
Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
+ T E H+ + +P + + A N G V K S
Sbjct: 12249 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 12296
Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666
+ L S+P P + ++ +++T PP L +G +
Sbjct: 12297 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 12338
Query: 667 ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716
E+ R T++S+ ++++ TG + A N+ G + V E
Sbjct: 12339 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 12397
Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
+ P I P +T G+ + I + G P PT W + G+ + H V + +
Sbjct: 12398 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 12456
Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
L++K V +G Y + +N G + ++ +++ ++ P
Sbjct: 12457 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 12500
Score = 42.0 bits (97), Expect = 0.006
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+T G +V + + G P PTV W +DG L K ++ ++ TL L V +
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12866
Query: 790 GQYEILLKNRVGECSCQVSL 809
G Y I +N G S + L
Sbjct: 12867 GDYTITAENSSGSKSATIKL 12886
Score = 42.0 bits (97), Expect = 0.006
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
VV+ G R GRP P W K + L S R + + L + N++D G
Sbjct: 21871 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 21928
Query: 231 YTCLVVNGSGKASMSAELSI 250
YT V N SG S++ + +
Sbjct: 21929 YTLTVENNSGSKSITFTVKV 21948
Score = 42.0 bits (97), Expect = 0.006
Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639
+ LA+NA G +S + T + + EY AP K L G DL + GS
Sbjct: 22517 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22567
Query: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
+ + V G P P++IW E+ E + G + + I+ D+G YT N
Sbjct: 22568 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22627
Query: 700 SAGEVRTQAVLTVQEPHDGTQP 721
++G T+AV + + D P
Sbjct: 22628 ASG---TKAVSVMVKVLDSPGP 22646
Score = 42.0 bits (97), Expect = 0.006
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
T D ++ P E + G+ V ++ G + G+P+P++ W KG+
Sbjct: 22539 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22588
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
L +VS+ I ++ D G YT V N SG ++S + + LDS
Sbjct: 22589 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22643
Score = 41.6 bits (96), Expect = 0.007
Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
+N+ + E TA FE V + P + W +NG I +F + ++G L+I
Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899
Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
ED +YT N + +TV E+TV EG K L
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959
Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
V K+ GD F A + +++ E +F +
Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
+ V E + F C+++ P V W+K + LQ + R+ + ++ + L I D
Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078
Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
G YT + +G +A+L ++G D RS +E +
Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3111
Score = 41.6 bits (96), Expect = 0.007
Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V + Q + CE++ + +V W +G V + G I L + A D+GT
Sbjct: 4727 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 4784
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+ T NA L CS ++V V + ++D V + C + P
Sbjct: 4785 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 4838
Query: 545 ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
I W + +P + L I++A+PED Y E A +T
Sbjct: 4839 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 4894
Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
+ E R+ E L P+ D+ + + + ++S P W
Sbjct: 4895 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 4935
Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
G ++ S + G + L + +V + G +A N+ T A+LTV+E
Sbjct: 4936 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 4987
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
+ F + VT + C + + V W + G + K + F+++ + L
Sbjct: 4988 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 5044
Query: 780 VLKKVQPWHAGQY 792
V+ Q G Y
Sbjct: 5045 VINDSQFDDEGVY 5057
Score = 41.6 bits (96), Expect = 0.007
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6025
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1862
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6026 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6073
Score = 41.6 bits (96), Expect = 0.007
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
A+ ISK S S P + + E P + P+ + + G T + E V G P P +
Sbjct: 17103 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17160
Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
W R + I R C I+ T L++ D G+Y A+N +G++ V +
Sbjct: 17161 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17216
Query: 122 TV 123
V
Sbjct: 17217 KV 17218
Score = 41.6 bits (96), Expect = 0.007
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++VK G + GRP P V W K + L+ A V ++ L I N++D G
Sbjct: 19699 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19756
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
YT + N AS++ L ++ LD+ T T DV KE
Sbjct: 19757 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19795
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+K ++++ + V G P P V WF +G + ++ ++E+ + GS L + A G
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 21531
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514
Y+ A NA G ++V+ V P
Sbjct: 21532 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 21561
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1813
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 26888
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
+LII DV D YT N G + T + + ++
Sbjct: 26889 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 26926
Score = 41.2 bits (95), Expect = 0.010
Identities = 24/96 (25%), Positives = 43/96 (44%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+C P + ++V EG+ P P V+W K ++ S R+++ +
Sbjct: 7887 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 7946
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
LE+ + D G+YT + N G A+ S + + GL
Sbjct: 7947 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 7982
Score = 41.2 bits (95), Expect = 0.010
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Query: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570
P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L +
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 7949
Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTV 600
++ D G YT EN LG + S V V
Sbjct: 7950 PKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 41.2 bits (95), Expect = 0.010
Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%)
Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454
VSK + P + QR P + K + EV+E V ++ G+P P + WF P
Sbjct: 9602 VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 9658
Query: 455 RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
++ + V D + L C L ++R D+G Y+ TA N G S L V
Sbjct: 9659 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9718
Query: 507 LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557
V P F SV D + +G + + R TW+ ++ +P
Sbjct: 9719 RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 9774
Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
C + +L L + +A+N G + + + ++ + +P AP
Sbjct: 9775 -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 9823
Query: 618 SKPT 621
KPT
Sbjct: 9824 DKPT 9827
Score = 41.2 bits (95), Expect = 0.010
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11018 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11076
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIV 1848
D +Y N+ G T L V
Sbjct: 11077 LRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 41.2 bits (95), Expect = 0.010
Identities = 23/80 (28%), Positives = 36/80 (45%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+ G++ ++ I G P P V W +DGK L + E+ TLV+K
Sbjct: 18220 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18279
Query: 790 GQYEILLKNRVGECSCQVSL 809
GQY + L N G S +++
Sbjct: 18280 GQYILKLSNVGGTKSIPITV 18299
Score = 41.2 bits (95), Expect = 0.010
Identities = 26/85 (30%), Positives = 34/85 (40%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V + G L+L V P IIWT K L + + L G + I+ D G
Sbjct: 22560 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22619
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191
Y KN +G S V V D+P
Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVLDSP 22644
Score = 40.8 bits (94), Expect = 0.012
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Query: 604 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W
Sbjct: 7174 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7233
Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+++ + E + ++ I + DTGTY EA N G R AV+ V
Sbjct: 7234 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7281
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 7198 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7256
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIV 1848
D Y +AVN G AT E+ V
Sbjct: 7257 KRSDTGTYIIEAVNVCGRATAVVEVNV 7283
Score = 40.8 bits (94), Expect = 0.012
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389
P PP + I ++ L W DGGS + +Y +E D K W+ + T + T
Sbjct: 7587 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7645
Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSE 1414
V L Y FRV A N G S+
Sbjct: 7646 TVTPLTEGSLYVFRVAAENAIGQSD 7670
Score = 40.8 bits (94), Expect = 0.012
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P IL P + IK G + E V G P P W + + + + + L+
Sbjct: 12402 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12460
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I V +D G Y+ A N SG +++ V
Sbjct: 12461 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12491
Score = 40.8 bits (94), Expect = 0.012
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%)
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
++ +A N +G +S L V +A + + P+F + V+ G+D + G P
Sbjct: 15621 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 15679
Query: 543 PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
P +TW + P+ Q R E+ + L I+DA ED G Y N+ G+ + V
Sbjct: 15680 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 15739
Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPI 624
V +K P PT P+
Sbjct: 15740 VLDK-------------PGPPTGPV 15751
Score = 40.8 bits (94), Expect = 0.012
Identities = 20/81 (24%), Positives = 39/81 (48%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G
Sbjct: 16056 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16115
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y N +G+ S++ + +
Sbjct: 16116 NYILKAKNVAGERSVTVNVKV 16136
Score = 40.8 bits (94), Expect = 0.012
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+
Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16802
Query: 104 YTCEATNGSGARQVTVEL 121
Y N G + ++E+
Sbjct: 16803 YGITVANVVGQKTASIEI 16820
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 17813 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17871
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I + DD KYT A NS G AT +IV
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/74 (31%), Positives = 33/74 (44%)
Query: 639 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
Q+ + V G P V W +G ++E+ + T SL I+E ED GTY
Sbjct: 18914 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 18973
Query: 699 NSAGEVRTQAVLTV 712
NSAG + + V
Sbjct: 18974 NSAGSITVPITIIV 18987
Score = 40.8 bits (94), Expect = 0.012
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)
Query: 711 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757
+V EP + T P + PR + G+ + I+ IAG P P + W +D
Sbjct: 19270 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19329
Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
G + ++ E++ ++ L +K GQY + LKN G S V+
Sbjct: 19330 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19379
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 5847
Query: 1820 DVCGDDDAKYTCKA 1833
D +D YTC A
Sbjct: 5848 DCTPEDIKTYTCDA 5861
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ ++ G T + RV+G PEP +TW + G+ + R L + L I D
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11479
Query: 102 GKYTCEATNGSGARQ 116
GKY A N SG Q
Sbjct: 11480 GKYIISAKNSSGHAQ 11494
Score = 40.4 bits (93), Expect = 0.016
Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V+ QT++ V G P+P++ W EG + R E +++ +D L + +A D G
Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 11481
Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
Y +A N+ G S + V + L V V ++ + + G + V
Sbjct: 11482 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 11541
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596
+P Q S + V + I+ + L + + AEN +G
Sbjct: 11542 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 11585
Query: 597 WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650
T+ K +L + P +P P +L + D + + ++ G
Sbjct: 11586 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 11633
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705
P + H ++ S+D+ +G+ + + + + N GE V+
Sbjct: 11634 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 11691
Query: 706 TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763
T+ V+ + D +P K V T G ++ + + G PFP V W +D A
Sbjct: 11692 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11748
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
+ ++ D L K + G+Y + N G
Sbjct: 11749 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11786
Score = 40.4 bits (93), Expect = 0.016
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
VK V V G P P V+W +GT ++ EG I++ L L +DSG
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 12868
Query: 485 YSCTASNAQGQLSCSWTLQV 504
Y+ TA N+ G S + L+V
Sbjct: 12869 YTITAENSSGSKSATIKLKV 12888
Score = 40.4 bits (93), Expect = 0.016
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%)
Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
S++ G ++ +++ R+++ P F + V G+ F L+ V G P+P I WL
Sbjct: 17111 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 17164
Query: 550 NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
+ I+ + + CE A L ++DA+ D G Y A N G S V V ++
Sbjct: 17165 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 17221
Query: 606 SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633
P P P+ + G++ K
Sbjct: 17222 -----------PGPPEGPVQVTGVTSEK 17238
Score = 40.0 bits (92), Expect = 0.021
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)
Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
DP+ V L E P IL R IK G T + ++G P P+VTW + +
Sbjct: 10702 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10761
Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ R +D G+ + +A H ED G Y+ N +G++ V+V++ V
Sbjct: 10762 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 10809
Score = 40.0 bits (92), Expect = 0.021
Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
VK T++ V G P PEVAW + T + R +++ A S L KA+ D
Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 11774
Query: 483 GTYSCTASNAQGQLSCSWTLQV 504
G Y TA+N G T+ V
Sbjct: 11775 GKYVVTATNTAGSFVAYATVNV 11796
Score = 40.0 bits (92), Expect = 0.021
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)
Query: 598 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
V V+EK S +P VA P S V G + + V +SG P P + W
Sbjct: 16707 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16766
Query: 657 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715
+G ++++ + +L I+E +D G Y N G+ + ++T+ +P
Sbjct: 16767 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 16826
Score = 40.0 bits (92), Expect = 0.021
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575
KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D +
Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18276
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
D G Y N G S V V ++ P P P+ + G++
Sbjct: 18277 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18318
Score = 40.0 bits (92), Expect = 0.021
Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%)
Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Q+ V+ +++ G P P W P +++ L +
Sbjct: 21868 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 21924
Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
D+G Y+ T N G S ++T++V + +V ++++ D +++G +
Sbjct: 21925 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 21984
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
V R +W Q C + +++ LAE
Sbjct: 21985 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 22024
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
SA V+E E P+ ++ AP L V+D S+ + +
Sbjct: 22025 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 22068
Query: 654 VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700
WL H+G Q+ DF E T Q + ++ + + + +A N
Sbjct: 22069 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 22126
Query: 701 AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
AG + + ++EP + T + +T G I I+G P P V W
Sbjct: 22127 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 22186
Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
+ L K+T + +D TL +K +G+Y + L+N G + V++++
Sbjct: 22187 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 22245
Query: 817 RAL-PRGREPASCED-LCGGGVGADGGGSD 844
P S E + G DGGG++
Sbjct: 22246 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22275
Score = 39.7 bits (91), Expect = 0.028
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103
G AKF ++ P + W + G+ I + C IR + SL I D G+
Sbjct: 4351 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4406
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
YTC+A+N G+ T LTV G+ V K L +R P E
Sbjct: 4407 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4449
Score = 39.7 bits (91), Expect = 0.028
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 1737 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 5494 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5552
Query: 1791 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5553 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5592
Score = 39.7 bits (91), Expect = 0.028
Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)
Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
PSR + ++ EAP L + L +K G + V G PEP++TW + +
Sbjct: 7175 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7234
Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
R ++ + ++ I D G Y EA N G VE+ V
Sbjct: 7235 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283
Score = 39.7 bits (91), Expect = 0.028
Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V E + + +P P V+W +G V+ + + + D S +L + K+ D+G
Sbjct: 7901 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 7959
Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
Y+ T N G + S ++V + + ++ S + + +G +L +
Sbjct: 7960 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 8019
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
R T++ P+ + V +D +P + A N +G
Sbjct: 8020 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 8063
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
E PV P P D++V + + MT+ + PP L
Sbjct: 8064 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 8107
Query: 658 HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712
++G +G + C + + P TYT + E VR + +
Sbjct: 8108 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 8165
Query: 713 QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
EP T P P S+ G + + +I+G P+PT+ W++D
Sbjct: 8166 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 8219
Score = 39.7 bits (91), Expect = 0.028
Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L I+ G GR G P+P+V+W ++ + R + T +L D
Sbjct: 10331 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10389
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
GKY N +G+R+ ++ V + G PV + F + W
Sbjct: 10390 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 10441
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221
+K+ ++++ ++G+ V + + + +VS + + IH
Sbjct: 10442 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10490
Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273
N G+ LV + SM A+ + D+ ++ V E ++ D K
Sbjct: 10491 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 10543
Query: 274 EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317
+TN I ++ + S A +K+ C R + P PP
Sbjct: 10544 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 10603
Query: 318 RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373
+ +K K SP P+ S +T Q R + G V G+E R
Sbjct: 10604 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 10663
Query: 374 PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420
A P + P T+ G +D K + G+ D A K +P
Sbjct: 10664 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 10723
Query: 421 -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
+ Q +K T++ + G+P P+V W E + I+V GS L +
Sbjct: 10724 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 10780
Query: 476 KARTRDSGTYSCTASNAQGQLSCS 499
A D G YS T N G + S
Sbjct: 10781 NAAHEDGGIYSLTVENPAGSKTVS 10804
Score = 39.7 bits (91), Expect = 0.028
Identities = 23/81 (28%), Positives = 34/81 (41%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VVK G RF I G P P W ++ +V N VL I + D G
Sbjct: 11023 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11082
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y V N +G +++ L++
Sbjct: 11083 EYQITVSNAAGSKTVAVHLTV 11103
Score = 39.7 bits (91), Expect = 0.028
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
+++ A + + + P V EAP L + + ++ G +A+ +G P
Sbjct: 17496 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17555
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P++TW R T + ++ G+ T L I D GKY + N SG++ V
Sbjct: 17556 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17612
Query: 121 LTV 123
+ V
Sbjct: 17613 VKV 17615
Score = 39.7 bits (91), Expect = 0.028
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V + G L L VS PP I W+ G L + I ++ SL + ++K D G
Sbjct: 22959 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23016
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191
Y A+N +G+ + V V D P
Sbjct: 23017 KYTIEAENQSGKKSATVLVKVYDTP 23041
Score = 39.3 bits (90), Expect = 0.036
Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779
P F +SV G + I+G P P V W RDG+ + T ++ ++ L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839
+ V ++G+Y + N G+ + L+++ +A P + L +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116
Query: 840 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893
G R G P + DG +++ L ++ E
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 894 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953
++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D
Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231
Query: 954 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005
RS+ + G + +P K PP P P RS + K +L + S
Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287
Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032
S P+ + + P PV + PA
Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310
Score = 39.3 bits (90), Expect = 0.036
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 7879 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 7938
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
D + L + D YT N LG AT + + V
Sbjct: 7939 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 39.3 bits (90), Expect = 0.036
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)
Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575
SV ++ G+ + V G PVP W + R + +EL I+DAL
Sbjct: 8612 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8671
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
+DHG Y A N+ G +A V V + +L + P + L SD +
Sbjct: 8672 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8726
Query: 636 DGSQVT 641
GS++T
Sbjct: 8727 GGSEIT 8732
Score = 39.3 bits (90), Expect = 0.036
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785
G + I I G P P W DGKA KD H E +N V +++ + +
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9385
Query: 786 PWHAGQYEILLKNRVGE--CSCQVSLM 810
H G+Y I KN+ G+ +C+V +M
Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVM 9412
Score = 39.3 bits (90), Expect = 0.036
Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 668 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
D HFE G H + + G ++ E S G + + V P P +
Sbjct: 15998 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16054
Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
++ G+S + I G P PT+ W++ + L +T E+ + +L +K
Sbjct: 16055 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16110
Query: 786 PWHAGQYEILLKNRVGECSCQVSL 809
+G Y + KN GE S V++
Sbjct: 16111 RVDSGNYILKAKNVAGERSVTVNV 16134
Score = 38.9 bits (89), Expect = 0.047
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ V G + + +V G P P++ W G + + Q + L I+E D G
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480
Query: 692 TYTCEAWNSAGEVRTQAVLTV 712
Y A NS+G + A++ V
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNV 11501
Score = 38.9 bits (89), Expect = 0.047
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
SV A G+ V + G P PTV W +D K L D + + + L + +V
Sbjct: 20783 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 20841
Query: 789 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
G+Y + ++N VGE SS ++ PA+C+ L
Sbjct: 20842 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 20875
Score = 38.9 bits (89), Expect = 0.047
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584
G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT +
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21140
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
+NA+ +++ V L P PSKP PI
Sbjct: 21141 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21167
Score = 38.5 bits (88), Expect = 0.062
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
G E+ T + PAP P PP ++ ++ V GESV L ++G T TW +
Sbjct: 875 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
QI+ S ++ ++L I A E G +T N+ G+ L V
Sbjct: 933 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 38.5 bits (88), Expect = 0.062
Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 614 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
PV ++P P + + +++M G + + V+G P P +W E+ + +
Sbjct: 8595 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8653
Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
+ GT+ L I++ +D G Y A NS G
Sbjct: 8654 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8686
Score = 38.5 bits (88), Expect = 0.062
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
L +K G T + E VRG P P+V W ++ +T R +D + FSL
Sbjct: 11714 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11771
Query: 99 EDRGKYTCEATNGSGA 114
D GKY ATN +G+
Sbjct: 11772 SDGGKYVVTATNTAGS 11787
Score = 38.5 bits (88), Expect = 0.062
Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%)
Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
IP EG+ D+ K + ++ T++ V G P P++ W +R + G ++
Sbjct: 13192 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 13244
Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515
+ +L D+G Y T N+ G+ + ++V + V E++
Sbjct: 13245 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 13304
Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
+ V + +I+G ++ V+ R +W + T E + +
Sbjct: 13305 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 13355
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
+ AEN G + + +R + V S+ P+ DLKV
Sbjct: 13356 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 13396
Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691
S+ + ++ G P G+ I DF E+ Q SL +Q + T
Sbjct: 13397 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 13450
Query: 692 ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744
T+ A N GE T + +TV D P K A + + I
Sbjct: 13451 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13509
Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
G P P+V W + L DT V + TL++ Q AG+Y I LKN G
Sbjct: 13510 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568
Query: 805 CQVSL 809
+S+
Sbjct: 13569 GTISI 13573
Score = 38.5 bits (88), Expect = 0.062
Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
PAF L + G K + G P P VTWH++ P+ R + L
Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15709
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I ED G Y + TN +G T+ + V G + + D +
Sbjct: 15710 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15764
Query: 153 PSIWGECPPKF 163
WG PPK+
Sbjct: 15765 ---WG--PPKY 15770
Score = 38.5 bits (88), Expect = 0.062
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17135 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17193
Query: 1824 DDDAKYTCKAVNSLG 1838
D +Y +A N G
Sbjct: 17194 IDGGQYILRASNVAG 17208
Score = 38.5 bits (88), Expect = 0.062
Identities = 22/83 (26%), Positives = 37/83 (44%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ K G I+GRP P+VTW + L+ + RVS++ L + + D G
Sbjct: 22160 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22219
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y + N +G + S + + G
Sbjct: 22220 RYFLTLENTAGVKTFSVTVVVIG 22242
Score = 38.1 bits (87), Expect = 0.081
Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)
Query: 541 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
PV W+ +N +PI+ + E GV +P+ A NA+G
Sbjct: 7828 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 7871
Query: 600 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
+ S SE ++ P KPT + D+ V++G ++++ V P P V W
Sbjct: 7872 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 7925
Query: 659 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717
+G E++ S+ + L + + D G YT N G V + P
Sbjct: 7926 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 7983
Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771
P K +T S SC + +P P +H++ + + + T + V+
Sbjct: 7984 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8033
Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
E+ + +K + P + + N+VG
Sbjct: 8034 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8063
Score = 37.7 bits (86), Expect = 0.11
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
Query: 620 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672
PT + L D +KV G V + V+G P P++ W N I++ D
Sbjct: 8898 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 8957
Query: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
+ + L I + ED GTYT A N G V
Sbjct: 8958 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 8989
Score = 37.7 bits (86), Expect = 0.11
Identities = 20/73 (27%), Positives = 33/73 (45%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V++K G+ R ++GRP P + W K L+ +A++ + + L + D G
Sbjct: 14974 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15033
Query: 230 VYTCLVVNGSGKA 242
YT N G A
Sbjct: 15034 AYTLTATNPGGFA 15046
Score = 37.7 bits (86), Expect = 0.11
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
+AP L P+ + + G T E +RG P P V W ++G+ + + R + I+
Sbjct: 18206 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18265
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
T +LV+ D G+Y + +N G + + + + V
Sbjct: 18266 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18301
Score = 37.7 bits (86), Expect = 0.11
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)
Query: 617 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663
PS+ T PI ++ + D+K D G + + ++G P P + W +G EI
Sbjct: 19274 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19333
Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
+E L +++ DTG Y N AG
Sbjct: 19334 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19372
Score = 37.7 bits (86), Expect = 0.11
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
+ G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21532
Query: 1169 KCVAKNDAGQAECSCQVTVDDAP 1191
AKN +G A+ +V V D P
Sbjct: 21533 TVEAKNASGSAKAEIKVKVQDTP 21555
Score = 37.4 bits (85), Expect = 0.14
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1825
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8673
Query: 1826 DAKYTCKAVNSLGEATCTAELIV 1848
+Y A NS G A + V
Sbjct: 8674 HGRYVITATNSCGSKFAAARVEV 8696
Score = 37.4 bits (85), Expect = 0.14
Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11479
Query: 790 GQYEILLKNRVG 801
G+Y I KN G
Sbjct: 11480 GKYIISAKNSSG 11491
Score = 37.4 bits (85), Expect = 0.14
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584
G + L +V G P+P ++W +G +P + + + + L + +D G YT
Sbjct: 12813 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12872
Query: 585 AENALGQVSCSAWVTVHEK 603
AEN+ G S + + V +K
Sbjct: 12873 AENSSGSKSATIKLKVLDK 12891
Score = 37.4 bits (85), Expect = 0.14
Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
VDP R+ P + + + G + K + + G P P + W + Q +++ R
Sbjct: 16041 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16092
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ T SL + D G Y +A N +G R VTV + V G V+S
Sbjct: 16093 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16151
Query: 139 TLGDR 143
++
Sbjct: 16152 VTAEK 16156
Score = 37.4 bits (85), Expect = 0.14
Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480
V+ + + G P PE+ W R+EG +V + G +Y L +
Sbjct: 17539 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 17591
Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
D+G Y N+ G S T++V + LAV EV + ++ + +I+G V
Sbjct: 17592 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 17651
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
+ R YA + + +++ + +AEN G
Sbjct: 17652 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 17699
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
V V + + +E P P K T + D SQ + ++ PE
Sbjct: 17700 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 17740
Query: 654 VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703
H+G + +GT+ +C V +G + +A+N G+
Sbjct: 17741 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 17796
Query: 704 VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
+ + D T QP + + G+ + I + G P P + W++DG+ L
Sbjct: 17797 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 17855
Query: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
K T V + L +K+ G+Y + N G + +S+++
Sbjct: 17856 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 37.4 bits (85), Expect = 0.14
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 1740 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 19670 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19728
Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 19729 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19779
Score = 37.4 bits (85), Expect = 0.14
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ +
Sbjct: 19985 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20043
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
D G+Y A N SG + + + V G V+S
Sbjct: 20044 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20083
Score = 37.4 bits (85), Expect = 0.14
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y +
Sbjct: 21476 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21534
Query: 795 LLKNRVGECSCQVSLMLQNSSARAL 819
KN G ++ + +Q++ + +
Sbjct: 21535 EAKNASGSAKAEIKVKVQDTPGKVV 21559
Score = 37.0 bits (84), Expect = 0.18
Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)
Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137
+ H G + + P + V V EG+ +C+V+ P + W LNG+
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834
Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195
++ +K + +G + + I D G K A+N G E ++ + S
Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893
Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
+APE RP+ + + + +P T K + + + +KV ES
Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949
Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290
EL K + IT +K RK+ + E + K +E
Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009
Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340
G K+TI L+ E + + +G A + VV KPDP
Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063
Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400
WY + IE D W E C ++D+ +
Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101
Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451
V+AIN+ G + Q +L T ++ ++ KD + + + EP V +
Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161
Query: 1452 VTINTEQKVSDFY 1464
E D Y
Sbjct: 2162 YKDGMEVHEGDKY 2174
Score = 37.0 bits (84), Expect = 0.18
Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%)
Query: 935 PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994
P+ V E + K+ Q+ DFRSVL + P P+ P+F GK + +
Sbjct: 1871 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1916
Query: 995 NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054
+T K V K + + K E + + + T + A
Sbjct: 1917 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 1967
Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101
LKS K+E +++ + H T+ EK++ E + T P FK
Sbjct: 1968 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2027
Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152
+++Q V +G + +V P W NG K ++ + E ++
Sbjct: 2028 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2087
Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178
C + I ED A N AG+
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGE 2113
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + VSG PPP V W N NE ++ E S+ I+ G Y+
Sbjct: 10042 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10099
Query: 697 AWNSAGEVRTQAVLTV 712
A N AGE + ++ V
Sbjct: 10100 AKNEAGERKKTIIVDV 10115
Score = 37.0 bits (84), Expect = 0.18
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 1763 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1819
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11416 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11472
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTA 1844
+ D KY A NS G A +A
Sbjct: 11473 EAVRADHGKYIISAKNSSGHAQGSA 11497
Score = 37.0 bits (84), Expect = 0.18
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 1749 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1802
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11690 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11749
Query: 1803 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
++ D + S ++ D KY A N+ G A + V
Sbjct: 11750 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796
Score = 37.0 bits (84), Expect = 0.18
Identities = 22/92 (23%), Positives = 40/92 (43%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + G ++ + V G P P W +E+ S + + L I++V +D+G
Sbjct: 12411 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12470
Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723
Y+ A NS+G + + V + QP F
Sbjct: 12471 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12502
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16511
Query: 1827 AKYTCKAVNSLG 1838
KYT NS G
Sbjct: 16512 GKYTLTLENSSG 16523
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 1758 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20431
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
S++I D + Y K N++G A+ T
Sbjct: 20432 SILIKDADRLNSGCYELKLRNAMGSASAT 20460
Score = 37.0 bits (84), Expect = 0.18
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V + G + I+G+P P + W K + LQ +A V V + + I ++ + G
Sbjct: 20385 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20444
Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254
Y + N G A SA + +Q LD
Sbjct: 20445 CYELKLRNAMGSA--SATIRVQILD 20467
Score = 36.6 bits (83), Expect = 0.23
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)
Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
RF A E R + PK T +VV G+ P+ + W K N PL
Sbjct: 6485 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6544
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ +E+ ++LE + D G Y ++ N GKA L +
Sbjct: 6545 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6589
Score = 36.6 bits (83), Expect = 0.23
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
V+EG KI G P P +TW K P +P + V + N + V L I
Sbjct: 9631 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9689
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
+ D G+YT VN G AS L++ G
Sbjct: 9690 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9718
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586
G L ++G P P++TW + AR ++L I++A ED G Y+ E
Sbjct: 10736 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 10795
Query: 587 NALGQVSCSAWVTVHEK 603
N G + S V V +K
Sbjct: 10796 NPAGSKTVSVKVLVLDK 10812
Score = 36.6 bits (83), Expect = 0.23
Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643
A+N G +S + T + K EY P PT L + G + +
Sbjct: 13853 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 13903
Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
+ + G P P+ W G +I+ S+ T L I+ +D G YT A N G
Sbjct: 13904 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 13963
Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
+TV + P IS + A+L
Sbjct: 13964 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 13994
Score = 36.6 bits (83), Expect = 0.23
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y
Sbjct: 19991 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20050
Query: 694 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725
A NS+G + ++ + P T P IS
Sbjct: 20051 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20083
Score = 36.6 bits (83), Expect = 0.23
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 1743 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22134 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22192
Query: 1800 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22193 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22240
Score = 36.2 bits (82), Expect = 0.31
Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 1076 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128
NC+ G D N K S P + L+DV V G+ C++S +
Sbjct: 5670 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5728
Query: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
+ W L GK L+ + ++ EG + ++++ ED G + AK+
Sbjct: 5729 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5774
Score = 36.2 bits (82), Expect = 0.31
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%)
Query: 438 SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
SG PKP+V+WF + V ++ + + L +KA+ DSG Y N+ G
Sbjct: 10346 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 10404
Query: 498 CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
+ V V P SF V KD VI
Sbjct: 10405 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 10434
Score = 36.2 bits (82), Expect = 0.31
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
++ + G++ + + G P PT+ WLR K + +++ E+ + L++K
Sbjct: 17137 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17195
Query: 789 AGQYEILLKNRVGECSCQVSL 809
GQY + N G S V++
Sbjct: 17196 GGQYILRASNVAGSKSFPVNV 17216
Score = 35.8 bits (81), Expect = 0.40
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P T L V +EG + + IT + V W N + + + L I
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4300
Query: 221 HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250
VN +D G Y C +N SGK + SA+L++
Sbjct: 4301 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4331
Score = 35.8 bits (81), Expect = 0.40
Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
T S ++ + E ++ +A N G + ++ L V + D P
Sbjct: 8854 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 8898
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
++ R S+ G+ + VK G+ +TG P P++ W K ++
Sbjct: 8899 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 8948
Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
+ VS L I ++D G YT N G + + + S R+
Sbjct: 8949 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9008
Query: 261 VRETKA 266
V + KA
Sbjct: 9009 VTDIKA 9014
Score = 35.8 bits (81), Expect = 0.40
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
G +V I G P PT W DG + K H+ V + L +K G+Y+I
Sbjct: 11028 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11086
Query: 795 LLKNRVGECSCQVSL 809
+ N G + V L
Sbjct: 11087 TVSNAAGSKTVAVHL 11101
Score = 35.8 bits (81), Expect = 0.40
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
EAP +L P L IK G T + G P P+ +W + G+ I +
Sbjct: 13877 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 13936
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ + +A + D G+YT ATN G + V++TV
Sbjct: 13937 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 13972
Score = 35.8 bits (81), Expect = 0.40
Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584
G + ++ V G P P +TW Q ++ + A L+I + + D G Y
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
A N +G+V + VH+ P PT PI
Sbjct: 14643 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14669
Score = 35.8 bits (81), Expect = 0.40
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16513
Query: 104 YTCEATNGSGARQVTVELTV 123
YT N SG + V + V
Sbjct: 16514 YTLTLENSSGTKSAFVTVRV 16533
Score = 35.8 bits (81), Expect = 0.40
Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P+ LP +K K + +G P+ V W ++GQ + R + T SL
Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-SLS 18956
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I +ED G Y +N +G+ +TV +T+
Sbjct: 18957 IKEASKEDVGTYELCVSNSAGS--ITVPITI 18985
Score = 35.8 bits (81), Expect = 0.40
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 1782 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20855
Score = 35.8 bits (81), Expect = 0.40
Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)
Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142
+T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + +
Sbjct: 26818 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 26877
Query: 1143 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ L ++ I +D GLY N+ G + + +
Sbjct: 26878 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 35.4 bits (80), Expect = 0.52
Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F + L ++ V+E + L C+VS P A +IW + + T + EG + I+
Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6026
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
A ED G Y C R P S +D
Sbjct: 6027 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6045
Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
VK + + I P++ ++ GE E ++ + W + K ++
Sbjct: 6046 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6095
Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
+ V L + A + G Y ++V G+ +A +LTV++K
Sbjct: 6096 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6142
Score = 35.4 bits (80), Expect = 0.52
Identities = 16/82 (19%), Positives = 37/82 (45%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
++ ++ G+ + + +G+P+P+V+W K + R + LE + D
Sbjct: 10330 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10389
Query: 229 GVYTCLVVNGSGKASMSAELSI 250
G Y +V N +G ++++
Sbjct: 10390 GKYCVVVENSTGSRKGFCQVNV 10411
Score = 35.4 bits (80), Expect = 0.52
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)
Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676
KP + L G+ L V G + + V G P PEV W + ++ S + R
Sbjct: 11703 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11760
Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+ + D G Y A N+AG A + V
Sbjct: 11761 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796
Score = 35.4 bits (80), Expect = 0.52
Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)
Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
+ +A+NA G +S + T + K E LP P + + V G
Sbjct: 17096 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17146
Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
+ V G P P + WL EI+ES + + L +++ D G Y A N
Sbjct: 17147 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17206
Query: 701 AG 702
AG
Sbjct: 17207 AG 17208
Score = 35.4 bits (80), Expect = 0.52
Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ +K G K + G P P ++W ++G I R + T L + D
Sbjct: 19302 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19360
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
G+Y N +G R V V V G ++ ++ S P + I
Sbjct: 19361 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19420
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205
K T + EG++ SCK+T LKGN + +P
Sbjct: 19421 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 19473
Query: 206 RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
V++ + V LEI V ++ + + C S S + I+ + +
Sbjct: 19474 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 19531
Query: 260 FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314
+VR K D+R + T + E ++ + AA S S R P + P
Sbjct: 19532 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 19587
Query: 315 QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373
PP + K+ +S K + A P+ + + + + S G E
Sbjct: 19588 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 19647
Query: 374 PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
A + R +G+ D S +++ +I E + + F ++ VK +
Sbjct: 19648 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19706
Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
G P P V W T +R + ++ + S L + A DSG Y+ T
Sbjct: 19707 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 19763
Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526
N S + ++V + V K+ AV+
Sbjct: 19764 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 19799
Score = 35.4 bits (80), Expect = 0.52
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V++G + R + I G+P P W K + A ++ SE + L I ++ D G
Sbjct: 23649 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23706
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y ++ N GK ++ ++ + G
Sbjct: 23707 TYDLVLENKCGKKAVYIKVRVIG 23729
Score = 35.4 bits (80), Expect = 0.52
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1816
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 25934
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
I D DD Y N GEA+ A L V
Sbjct: 25935 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
Score = 35.0 bits (79), Expect = 0.68
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5345 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5402
Query: 1820 DVCGDDDAKYTCKA 1833
+D+AKY +A
Sbjct: 5403 SAAFEDEAKYMFEA 5416
Score = 35.0 bits (79), Expect = 0.68
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
R+VV G + R ++G+P P VTW L A + + + V I +
Sbjct: 10036 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10093
Query: 229 GVYTCLVVNGSGK 241
GVY+ L N +G+
Sbjct: 10094 GVYSLLAKNEAGE 10106
Score = 35.0 bits (79), Expect = 0.68
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
++ G + VRG P P+VTW + G + G L+D LVI +D
Sbjct: 12121 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12176
Query: 102 GKYTCEATNGSGARQVTVELTV 123
GKY+ N +G + V V + V
Sbjct: 12177 GKYSLTLVNPAGEKAVFVNVRV 12198
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12866
Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
YT A NS G + T +L V
Sbjct: 12867 GDYTITAENSSGSKSATIKLKV 12888
Score = 35.0 bits (79), Expect = 0.68
Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 615 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
VA AP + L+GL DL + + S + + + G P P V W + +
Sbjct: 13475 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13534
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721
E +L + + D G YT N AG + T ++ V +P T P
Sbjct: 13535 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13585
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
D + AP + P+I K G +V + I G+P P+ +W K +
Sbjct: 13874 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 13923
Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
+PS ++ +L I + D G YT N G
Sbjct: 13924 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
+V G ++ + I+G P P V RDG L K T F + T+ LK+
Sbjct: 19988 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20046
Query: 789 AGQYEILLKNRVGECSCQVSLML 811
AG+YEI N G +++++
Sbjct: 20047 AGRYEITAANSSGTTKAFINIVV 20069
Score = 35.0 bits (79), Expect = 0.68
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565
V+++ ++ V+K A G L+ + G P P I W + + +Q C +
Sbjct: 20374 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 20430
Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
A + I+DA + G Y NA+G S + V + +K
Sbjct: 20431 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20468
Score = 34.7 bits (78), Expect = 0.89
Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%)
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
V P+ W G PV + + E+ G Y Y A N QG
Sbjct: 7127 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 7173
Query: 497 SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553
S T +++ + E F V L V G L +V G P P+ITW
Sbjct: 7174 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7233
Query: 554 I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
+ Q R T E + + I D+ D GTY A N G+ + V V +K
Sbjct: 7234 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7286
Score = 34.7 bits (78), Expect = 0.89
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
G + + G P P + W+ E+ + + SL +++ D+G Y +
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16120
Query: 697 AWNSAGE 703
A N AGE
Sbjct: 16121 AKNVAGE 16127
Score = 34.7 bits (78), Expect = 0.89
Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%)
Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451
+SK ++ P+ + + P+ P+ ++ V +T + +V G P P + W L G
Sbjct: 17107 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 17165
Query: 452 TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
+ E+ L + A D G Y ASN G S
Sbjct: 17166 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 17211
Score = 34.7 bits (78), Expect = 0.89
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ AT + ++G PEP+V W + +T + + +F+ LVI V D G
Sbjct: 18622 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18677
Query: 103 KYTCEATNGSGARQVTVELTV 123
+Y N SG++ V + V
Sbjct: 18678 RYNLTLENNSGSKTAFVNVRV 18698
Score = 34.7 bits (78), Expect = 0.89
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 18896 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 18954
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I + +D Y NS G T +IV
Sbjct: 18955 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 18987
Score = 34.3 bits (77), Expect = 1.2
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6149 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6206
Query: 1824 DDDAKYTCKAVNSLGE-ATCTAELIVE 1849
DD A Y N GE A LIVE
Sbjct: 6207 DDQANYNVSLTNHRGENVKSAANLIVE 6233
Score = 34.3 bits (77), Expect = 1.2
Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%)
Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470
+A PK ++ Q V + + PK E WF E P+ + +I+ + S
Sbjct: 6500 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 6556
Query: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523
+L+A+ D G Y N G+ L+ V L V E S+ +
Sbjct: 6557 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 6615
Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLL 549
+ +G ++ V + R TW+L
Sbjct: 6616 PLTDGGSKIIGYVVERRDIKRKTWVL 6641
Score = 34.3 bits (77), Expect = 1.2
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
G+ L S +K +S DPS + PLT AF+ P +L K+G +
Sbjct: 6862 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 6919
Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
GYP P TW + + +G R + + LVI D+G YT + N
Sbjct: 6920 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 6974
Score = 34.3 bits (77), Expect = 1.2
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
G + VK G R + G+P P+V W K L S RV + + + +
Sbjct: 11712 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11771
Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250
D G Y N +G A +++
Sbjct: 11772 SDGGKYVVTATNTAGSFVAYATVNV 11796
Score = 34.3 bits (77), Expect = 1.2
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 1761 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17531 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17586
Query: 1821 VCGDDDA-KYTCKAVNSLG 1838
C +DA KY K NS G
Sbjct: 17587 NCDRNDAGKYILKLENSSG 17605
Score = 34.3 bits (77), Expect = 1.2
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
P V + E P + L R + +++G + ++G P P W + GQ I+
Sbjct: 23625 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23682
Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
R ++ T LVI D G Y N G + V +++ V GS
Sbjct: 23683 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23730
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
+ G + I ++G P PTV W + + L ++ + ++V+K Q H
Sbjct: 10037 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10093
Query: 790 GQYEILLKNRVGE 802
G Y +L KN GE
Sbjct: 10094 GVYSLLAKNEAGE 10106
Score = 33.9 bits (76), Expect = 1.5
Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%)
Query: 537 VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
+RG PVP W +G I ++ + + L I++ L D G Y NA G +
Sbjct: 11037 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11096
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
+ +TV + P PT PI ++D + MT +S PP +
Sbjct: 11097 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 11133
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15037
Query: 1832 KAVNSLGEA 1840
A N G A
Sbjct: 15038 TATNPGGFA 15046
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)
Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
+P+ V P E +LPP + + I+ T + ++G P P+V W R+
Sbjct: 15344 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15401
Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
G L I T S L++ V+ D GKY N SG++ V + V
Sbjct: 15402 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15451
Score = 33.9 bits (76), Expect = 1.5
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
+ + G + + V + G P PEV W EI+++ T SL + V D+G
Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16512
Query: 692 TYTCEAWNSAG 702
YT NS+G
Sbjct: 16513 KYTLTLENSSG 16523
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
+++ P V + +T E +P + ++ G E +G P+P ++W ++G P+
Sbjct: 21050 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21109
Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
F+ +L I +E GKYT N ++ V +TV
Sbjct: 21110 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21154
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 1745 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1794
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 22931 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 22985
Query: 1795 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 22986 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23032
Score = 33.5 bits (75), Expect = 2.0
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5079 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5136
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+V DD ++ + + E + TA+L V
Sbjct: 5137 EVTLDDISQIKAQ----VKELSSTAQLKV 5161
Score = 33.5 bits (75), Expect = 2.0
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5434 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5491
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCT 1843
D+ DD ++ +A+ EA T
Sbjct: 5492 DLSIDDTSQIRVEAMGMSSEAKLT 5515
Score = 33.5 bits (75), Expect = 2.0
Identities = 20/72 (27%), Positives = 32/72 (44%)
Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
TG P+P TW G+ L+ RV + + L I + D G+YT + N S
Sbjct: 6922 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 6981
Query: 245 SAELSIQGLDSA 256
++++ SA
Sbjct: 6982 EIDVNVIARPSA 6993
Score = 33.5 bits (75), Expect = 2.0
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)
Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
S IS+ ++ DP P L ++ + EG R P P V+WH++
Sbjct: 7875 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 7926
Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
G+ + + R + V +V D G YT N G+ ++ + V G
Sbjct: 7927 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 7981
Score = 33.5 bits (75), Expect = 2.0
Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582
G L+ VRG P P + W + RS A ++ + A D G Y
Sbjct: 11719 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11778
Query: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
A N G A V V +K ++ ++ V+ + T
Sbjct: 11779 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 11817
Score = 33.5 bits (75), Expect = 2.0
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
+ L ++ G T + V+G P P++TW + + R LD I+ T F + V
Sbjct: 13204 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13259
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
++ D GKY N G ++ T+ + V
Sbjct: 13260 NKYDAGKYILTLENSCGKKEYTIVVKV 13286
Score = 33.5 bits (75), Expect = 2.0
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
VK V S S S DP E P F + + L +K GA+ RG P
Sbjct: 19660 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19717
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P V W + + + R +D T SL I + D GKYT N A +T+
Sbjct: 19718 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19774
Query: 121 LTV 123
+ V
Sbjct: 19775 VKV 19777
Score = 33.5 bits (75), Expect = 2.0
Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572
S + K V G F + RG PVP + W +P R+ + L I++
Sbjct: 19693 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19749
Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTV 600
A D G YT +N L S + V V
Sbjct: 19750 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19777
Score = 33.5 bits (75), Expect = 2.0
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G
Sbjct: 19699 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19756
Query: 692 TYTCEAWN 699
YT N
Sbjct: 19757 KYTLTIQN 19764
Score = 33.1 bits (74), Expect = 2.6
Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G KL+ + +LSV+ ++ I R+L E FE + +
Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W+ + I ++ ++ + + L + + ++D GKYT A G + +L
Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
TV G +SK L D+ V E Q F
Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C++ P + WL+ L + + + L I DD+G YT V
Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653
Query: 242 ASMSAE 247
A + E
Sbjct: 2654 AKLKVE 2659
Score = 33.1 bits (74), Expect = 2.6
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 1725 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1770
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 5119 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5178
Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 5179 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5235
Query: 1831 CKAVNSLGEATCTAE 1845
C +A T E
Sbjct: 5236 CDCGTDKTKANVTVE 5250
Score = 33.1 bits (74), Expect = 2.6
Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%)
Query: 442 KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501
K EV W L V Q ++ + H L + + RD G Y A + + +
Sbjct: 6442 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 6498
Query: 502 LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561
+ AP + +D V G+ + P W +P+
Sbjct: 6499 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 6550
Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQ 591
A I +A D G Y + +N G+
Sbjct: 6551 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6580
Score = 33.1 bits (74), Expect = 2.6
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160
+ V G+ + + V+ P I W+ N + K T + +++E + +SI KA
Sbjct: 8911 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 8970
Query: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
+ ED+G Y A N G + V V D P+
Sbjct: 8971 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9002
Score = 33.1 bits (74), Expect = 2.6
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10785
Query: 1825 DDAKYTCKAVNSLGEATCTAELIV 1848
D Y+ N G T + +++V
Sbjct: 10786 DGGIYSLTVENPAGSKTVSVKVLV 10809
Score = 33.1 bits (74), Expect = 2.6
Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575
+D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D +
Sbjct: 19299 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19357
Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
D G Y +N G S + V +K P P P+ + GL+
Sbjct: 19358 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19399
Score = 33.1 bits (74), Expect = 2.6
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ GA+ + +G P P W + ++ D +FS L + + D G
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 21927
Query: 103 KYTCEATNGSGARQVTVELTV 123
KYT N SG++ +T + V
Sbjct: 21928 KYTLTVENNSGSKSITFTVKV 21948
Score = 32.7 bits (73), Expect = 3.4
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 1824 DDDAKYTCKAVNSLGEAT 1841
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 3.4
Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163
G ++ + + P W +GK K K + L + + I +
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9387
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
G Y AKN AGQ +C+V V D P
Sbjct: 9388 HTGKYSITAKNKAGQKTANCRVKVMDVP 9415
Score = 32.7 bits (73), Expect = 3.4
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1830
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22622
Query: 1831 CKAVNSLG 1838
N+ G
Sbjct: 22623 LTVKNASG 22630
Score = 32.3 bits (72), Expect = 4.4
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 1765 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6062 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6117
Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
D Y V +G A A L V
Sbjct: 6118 LQDMGTY----VVMVGAARAAAHLTV 6139
Score = 32.3 bits (72), Expect = 4.4
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 614 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
P+ AP + L L + G +T + SG P P+V W + ++ E + H
Sbjct: 10311 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10370
Query: 672 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702
+ T +L ++++ + D+G Y NS G
Sbjct: 10371 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10401
Score = 32.3 bits (72), Expect = 4.4
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575
KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+
Sbjct: 14971 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15029
Query: 576 EDHGTYTCLAENALG 590
D G YT A N G
Sbjct: 15030 RDSGAYTLTATNPGG 15044
Score = 32.3 bits (72), Expect = 4.4
Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)
Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584
G + + + G P+P++T +G P++ AE +++++++ D G Y
Sbjct: 19994 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20053
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635
A N+ G + V ++ P PT P+ + +++ V
Sbjct: 20054 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20100
Query: 636 DGSQVT 641
GSQVT
Sbjct: 20101 GGSQVT 20106
Score = 32.3 bits (72), Expect = 4.4
Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
P + L+ +K G+ V + +SG P P + W + E+Q + E S
Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20432
Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
+ I++ ++G Y + N+ G A + VQ
Sbjct: 20433 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20464
Score = 32.3 bits (72), Expect = 4.4
Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
+P + + + G + + G P P +W G + R ++ + L I
Sbjct: 23246 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23304
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
D G+YT E N +G T+++ +
Sbjct: 23305 TIRDTGEYTLELKNVTGTTSETIKVII 23331
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 1760 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187
Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ D Y+C V T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)
Query: 1694 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1746
W K G V+ I + S M +I ++ K G+ + + A L + VS +
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399
Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
+ + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 1763 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1819
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12114 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12169
Query: 1820 DVCGDDDAKYTCKAVNSLGE 1839
+ DD KY+ VN GE
Sbjct: 12170 NSTRDDSGKYSLTLVNPAGE 12189
Score = 32.0 bits (71), Expect = 5.8
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786
R++ G S+ I I G P P V W +D L K+ + E N + FT L++ +
Sbjct: 14287 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14342
Query: 787 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819
+ G++ + ++N G+ S V++ + ++ L
Sbjct: 14343 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14375
Score = 32.0 bits (71), Expect = 5.8
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18276
Query: 1824 DDDAKYTCKAVN 1835
D +Y K N
Sbjct: 18277 TDGGQYILKLSN 18288
Score = 32.0 bits (71), Expect = 5.8
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
K G+ + + G P P+VTW + R + + +L + D G+Y
Sbjct: 22163 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22221
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
N +G + +V + V G G VS + E+ WGE
Sbjct: 22222 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22273
Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+
Sbjct: 22274 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22326
Score = 31.6 bits (70), Expect = 7.6
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13557
Query: 1831 CKAVNSLG--EATCTAELI 1847
N G E T + +++
Sbjct: 13558 ITLKNVAGTKEGTISIKVV 13576
Score = 31.6 bits (70), Expect = 7.6
Identities = 19/80 (23%), Positives = 30/80 (37%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V +T ++ G P P+V W +G + +E+ L + D G
Sbjct: 18222 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281
Query: 485 YSCTASNAQGQLSCSWTLQV 504
Y SN G S T++V
Sbjct: 18282 YILKLSNVGGTKSIPITVKV 18301
Score = 31.6 bits (70), Expect = 7.6
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694
G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y
Sbjct: 18225 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283
Query: 695 CEAWNSAG 702
+ N G
Sbjct: 18284 LKLSNVGG 18291
Score = 31.2 bits (69), Expect = 9.9
Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 1733 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 1779
E L+ E+ ++ E+ EE VK P + D EG
Sbjct: 4205 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4264
Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 1838
I EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G
Sbjct: 4265 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4321
Query: 1839 EATCTAELIV 1848
+ +A+L V
Sbjct: 4322 KTATSAKLTV 4331
Score = 31.2 bits (69), Expect = 9.9
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 1076 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1135
NC+ + T K E A F K Q++ + EG+K C +S + + W +
Sbjct: 6036 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 6091
Query: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
KTL++ + +G + ++ A +D G Y + G A + +TV
Sbjct: 6092 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 6139
Score = 31.2 bits (69), Expect = 9.9
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14287 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14343
Query: 1825 DDAKYTCKAVNSLGE 1839
D K+ N G+
Sbjct: 14344 DTGKFVMTIENPAGK 14358
Score = 31.2 bits (69), Expect = 9.9
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 685
L V G + + V + G P PEV W L N I+ +E F L I E
Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 14340
Query: 686 FPEDTGTYTCEAWNSAGE 703
DTG + N AG+
Sbjct: 14341 NRYDTGKFVMTIENPAGK 14358
Score = 31.2 bits (69), Expect = 9.9
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1830
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14640
Query: 1831 CKAVNSLGE 1839
A N +GE
Sbjct: 14641 LTARNIVGE 14649
Score = 31.2 bits (69), Expect = 9.9
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
+V G++ + ++G P PT+ W +DGK L + T E+ + LV K
Sbjct: 14973 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 15031
Query: 789 AGQYEILLKNRVG 801
+G Y + N G
Sbjct: 15032 SGAYTLTATNPGG 15044
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 1765 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19299 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19357
Query: 1824 DDDAKYTCKAVNSLG 1838
D +Y N G
Sbjct: 19358 RDTGQYVLTLKNVAG 19372
Score = 31.2 bits (69), Expect = 9.9
Identities = 19/71 (26%), Positives = 30/71 (42%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V V+ G + I+G+P P+VT + VPL+ + R + + + D G
Sbjct: 19989 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20048
Query: 230 VYTCLVVNGSG 240
Y N SG
Sbjct: 20049 RYEITAANSSG 20059
Score = 31.2 bits (69), Expect = 9.9
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1830
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 21875 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 21930
Query: 1831 CKAVNSLGEATCT 1843
N+ G + T
Sbjct: 21931 LTVENNSGSKSIT 21943
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 583
V +G L ++G P P W GQ I + A EL I++A D GTY
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 23710
Query: 584 LAENALGQ 591
+ EN G+
Sbjct: 23711 VLENKCGK 23718
>gi|146219832 myosin light chain kinase 3 [Homo sapiens]
Length = 819
Score = 236 bits (601), Expect = 2e-61
Identities = 149/364 (40%), Positives = 195/364 (53%), Gaps = 72/364 (19%)
Query: 1411 GTSEPSQES------ELTTVGEKPEEPKDEVEVSDDDEKEPE-VDYRTVTINTEQKVSDF 1463
G EP Q+ V P + V DD P ++R V++ E +S
Sbjct: 454 GNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSPAPPAPFEHRVVSVK-ETSISAG 512
Query: 1464 YDI--EERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKL 1521
Y++ E LG G+FGQV R EK T A K K SAK++E+++ EI+IMN L H L
Sbjct: 513 YEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNL 572
Query: 1522 VQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGI 1581
+Q DAFE K + +V+E V GGELF+RI DE + LTE + + + RQI EGV Y+H+ I
Sbjct: 573 IQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYI 632
Query: 1582 VHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYA 1641
+HLDLKPENI+CVN+TG +IK+IDFGLARR + LKV FGTPEF+APEV+NYE + +
Sbjct: 633 LHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFP 692
Query: 1642 TDMWSIGVICYIL------------------------------------------NRL-- 1657
TDMWS+GVI Y+L +RL
Sbjct: 693 TDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLV 752
Query: 1658 -------DCTQCLQHPWLMKDTKNMEAK-KLSKDRMK------KYMARRKWQKTGNAVRA 1703
TQCL+H WL N+ AK SK R+K KY+A+RKW+K V A
Sbjct: 753 KEKSCRMSATQCLKHEWL----NNLPAKASRSKTRLKSQLLLQKYIAQRKWKKHFYVVTA 808
Query: 1704 IGRL 1707
RL
Sbjct: 809 ANRL 812
>gi|167466233 myosin light chain kinase family, member 4 [Homo
sapiens]
Length = 388
Score = 221 bits (562), Expect = 7e-57
Identities = 122/287 (42%), Positives = 175/287 (60%), Gaps = 15/287 (5%)
Query: 1448 DYRTVTINTEQKVSDFYDIE--ERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN 1505
D+R VT + V+ FY + E LG G+FGQV + E T A K K K+KE
Sbjct: 89 DHRIVTAK-QGAVNSFYTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEE 147
Query: 1506 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 1565
++ EIS+MN L H L+Q DAFE K +IV+V+E V GGELF+RIIDE + LTE + I +
Sbjct: 148 VKNEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILF 207
Query: 1566 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTP 1625
M+QI EG+ ++H+ I+HLDLKPENI+CVN+ +IK+IDFGLARR + LKV FGTP
Sbjct: 208 MKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTP 267
Query: 1626 EFVAPEVINYEPIGYATDMWSIGVICYIL-----------NRLDCTQCLQHPWLMKDTKN 1674
EF+APEV+NY+ + + TDMWS+GVI Y+L + L W ++D +
Sbjct: 268 EFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEF 327
Query: 1675 MEAKKLSKDRMKKYMARRK-WQKTGNAVRAIGRLSSMAMISGLSGRK 1720
+ + +K+ + K + + K W+ + + LS + S L+ +K
Sbjct: 328 QDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHSRLNAQK 374
>gi|14993776 skeletal myosin light chain kinase [Homo sapiens]
Length = 596
Score = 220 bits (560), Expect = 1e-56
Identities = 132/358 (36%), Positives = 186/358 (51%), Gaps = 56/358 (15%)
Query: 1415 PSQESELTTVGEKPEEPKDEVEVSDDDEKEPE-VDYRTVTINTEQKVSDF-YDIEERLGS 1472
PS++SE+ +D ++ DD P +R V + T S+F + +E LG
Sbjct: 234 PSEKSEVGQALCLTAREEDCFQILDDCPPPPAPFPHRMVELRTGNVSSEFSMNSKEALGG 293
Query: 1473 GKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKA 1532
GKFG V +EK T A K K + K+KE + EI +MN L+H L+Q A E
Sbjct: 294 GKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIETPH 353
Query: 1533 NIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIM 1592
IV+ +E + GGELFERI+DED+ LTE + + ++RQI +G+ ++HK ++HLDLKPENI+
Sbjct: 354 EIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENIL 413
Query: 1593 CVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1652
CVN TG +K+IDFGLARR LKV FGTPEF++PEV+NY+ I TDMWS+GVI Y
Sbjct: 414 CVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGVITY 473
Query: 1653 IL---------------------------------------------------NRLDCTQ 1661
+L R++ Q
Sbjct: 474 MLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQ 533
Query: 1662 CLQHPW---LMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGL 1716
CL HPW L + K + S+ +KKY+ +R+W+K AV A R ++ L
Sbjct: 534 CLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGAL 591
>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
Length = 1430
Score = 200 bits (509), Expect = 9e-51
Identities = 122/364 (33%), Positives = 188/364 (51%), Gaps = 72/364 (19%)
Query: 1452 VTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKE------KEN 1505
+T+ ++ V D+YD E LGSG+F V + EK T +A KF K K +E+
Sbjct: 1 MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRED 60
Query: 1506 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 1565
I +E+SI+ + HP ++ + +E K +++++LE+V+GGELF+ + +++ LTE E ++
Sbjct: 61 IEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKE-SLTEEEATEF 119
Query: 1566 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKT--GTRIKLIDFGLARRLENAGSLKVLFG 1623
++QI GV Y+H I H DLKPENIM +++ RIK+IDFGLA +++ K +FG
Sbjct: 120 LKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFG 179
Query: 1624 TPEFVAPEVINYEPIGYATDMWSIGVICYIL----------------------------- 1654
TPEFVAPE++NYEP+G DMWSIGVI YIL
Sbjct: 180 TPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDE 239
Query: 1655 ----------------------NRLDCTQCLQHPWLM-KDTKNMEAKKLS---KDRMKKY 1688
R+ LQHPW+ KDT+ ++K S ++ KK+
Sbjct: 240 YFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKF 299
Query: 1689 MARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEA 1748
AR+KW+++ + RLS S LS S L+ E + V +A + A
Sbjct: 300 AARKKWKQSVRLISLCQRLSR----SFLSRSNMSVARSDDTLD----EEDSFVMKAIIHA 351
Query: 1749 VAEE 1752
+ ++
Sbjct: 352 INDD 355
>gi|4557511 death-associated protein kinase 3 [Homo sapiens]
Length = 454
Score = 191 bits (485), Expect = 6e-48
Identities = 95/206 (46%), Positives = 138/206 (66%), Gaps = 9/206 (4%)
Query: 1457 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFK------AYSAKEKENIRQEI 1510
++ V D Y++ E LGSG+F V + +K T K +A KF K + +E I +E+
Sbjct: 6 QEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREV 65
Query: 1511 SIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQIS 1570
+I+ + HP ++ D FE K ++V++LE+VSGGELF+ + +++ LTE E ++++QI
Sbjct: 66 NILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKE-SLTEDEATQFLKQIL 124
Query: 1571 EGVEYIHKQGIVHLDLKPENIMCVNKT--GTRIKLIDFGLARRLENAGSLKVLFGTPEFV 1628
+GV Y+H + I H DLKPENIM ++K RIKLIDFG+A ++E K +FGTPEFV
Sbjct: 125 DGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFV 184
Query: 1629 APEVINYEPIGYATDMWSIGVICYIL 1654
APE++NYEP+G DMWSIGVI YIL
Sbjct: 185 APEIVNYEPLGLEADMWSIGVITYIL 210
>gi|14670383 death-associated kinase 2 [Homo sapiens]
Length = 370
Score = 189 bits (479), Expect = 3e-47
Identities = 97/206 (47%), Positives = 136/206 (66%), Gaps = 9/206 (4%)
Query: 1457 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAK------EKENIRQEI 1510
+QKV DFYDI E LGSG+F V + EK T +A KF K ++ +E I +E+
Sbjct: 16 QQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREV 75
Query: 1511 SIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQIS 1570
SI+ + H ++ D +E + ++V++LE+VSGGELF+ + ++ L+E E +++QI
Sbjct: 76 SILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE-SLSEEEATSFIKQIL 134
Query: 1571 EGVEYIHKQGIVHLDLKPENIMCVNKTGT--RIKLIDFGLARRLENAGSLKVLFGTPEFV 1628
+GV Y+H + I H DLKPENIM ++K IKLIDFGLA +E+ K +FGTPEFV
Sbjct: 135 DGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFV 194
Query: 1629 APEVINYEPIGYATDMWSIGVICYIL 1654
APE++NYEP+G DMWSIGVI YIL
Sbjct: 195 APEIVNYEPLGLEADMWSIGVITYIL 220
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 186 bits (471), Expect = 2e-46
Identities = 141/480 (29%), Positives = 206/480 (42%), Gaps = 69/480 (14%)
Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQ 423
LSP EE P P T PT +P S + NRR G + A P F+ Q
Sbjct: 831 LSPP-EEFPEPGETWPRT-PTMKP--------SPSQNRRSSDTGSK--APPTFKVSLMDQ 878
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
V+E Q V V G PKP V+W PVR + + G L +L A D+G
Sbjct: 879 SVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAG 938
Query: 484 TYSCTASNAQGQLSCSWTLQV----ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 539
Y+C A N G C L+V E ++ +AP L+D V G+ + +C V G
Sbjct: 939 FYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAP-----LQDVDVGAGEMALFECLVAG 993
Query: 540 TPVPRITWLLNGQPIQYARSTC----EAGVAELHIQDALPEDHGTYTCLAENALGQVSCS 595
+ WL G+ +Q A C + +L + +D G YTC A +++CS
Sbjct: 994 PTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCS 1053
Query: 596 AWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI 655
A +TV PS AP+F + L D++V++G ++SG PPP V
Sbjct: 1054 ARLTVR---------------PS--LAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVT 1096
Query: 656 WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
W H G ++ESE+ Q G HSL I V ED G Y A N+ G+ A L V+EP
Sbjct: 1097 WTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEP 1156
Query: 716 HDGTQ--------------------------PWFISKPRSVTASLGQSVLISCAIAGDPF 749
P F+ + + L + ++ C + G P+
Sbjct: 1157 RTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPY 1216
Query: 750 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
PT+ W +G + + + + Q DV LV V P HAG Y+ ++ N++G+ +C L
Sbjct: 1217 PTISWFHNGHRI-QSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHL 1275
Score = 167 bits (422), Expect = 1e-40
Identities = 167/632 (26%), Positives = 245/632 (38%), Gaps = 82/632 (12%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P F L VVV G C IT P PQV+W K L+ R+ + + L +
Sbjct: 722 PVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLL 781
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
D G Y N G+A+ +A L+++ + S +T S
Sbjct: 782 REARAADAGSYMATATNELGQATCAASLTVR------------PGGSTSPFSSPIT---S 826
Query: 281 KESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK 340
E L E P+ G + P +P P + + D+ AP T +
Sbjct: 827 DEEYLSPPE--------EFPEPGETWPRTPTMKPSPSQNRR---SSDTGSKAPPTFKVSL 875
Query: 341 TSSSI-----TLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPG------- 388
S+ + + RVQ EP+ P + L ++P P F G
Sbjct: 876 MDQSVREGQDVIMSIRVQGEPK-PVVSWL-----RNRQPVRPDQRRFAEEAEGGLCRLRI 929
Query: 389 LGSQD-----VVSKAANR--------RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRC 435
L ++ KA N R+ + +S + Q +V + F C
Sbjct: 930 LAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFEC 989
Query: 436 EVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQ 495
V+G EV W G ++ +++ D L L DSG Y+C S A+ +
Sbjct: 990 LVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDE 1049
Query: 496 LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ 555
L+CS L V +AP F+ +L+D V+EG+ C + GTP P +TW G P++
Sbjct: 1050 LTCSARLTVRP----SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPME 1105
Query: 556 YA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS-----SR 607
+ R + G+ LHI ED G Y A N GQ CSA + V E ++ S
Sbjct: 1106 ESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSS 1165
Query: 608 KSEYLLPVAPSKP--------TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
K E + P P +P + P FL+ L DL+V + + QV+G P P + W HN
Sbjct: 1166 KLEKM-PSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHN 1224
Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE----P 715
G+ IQ S+D Q H L V P+ G Y N G+ A L V + P
Sbjct: 1225 GHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGP 1284
Query: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGD 747
DG R VT + + AI D
Sbjct: 1285 PDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPD 1316
Score = 146 bits (368), Expect = 2e-34
Identities = 153/593 (25%), Positives = 229/593 (38%), Gaps = 106/593 (17%)
Query: 295 KNCSSPQRGGSPPWAAN---SQPQPPRESKLESCKDSPRTAP-QTPVLQKTSSSITLQAA 350
+ C SP PP AA+ ++ + P K E + R P TP L+ + TL+
Sbjct: 605 QECRSPV----PPPAADPPEARTKAPPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKN 660
Query: 351 RVQPEPRAPGLGVLSPSGEERKRPAPPRPATF-PTRQPGLGSQDVVSKAANRRIPMEGQR 409
R PE E+R R P + P + G SQ +A +E
Sbjct: 661 RAGPE------------AEKRLRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPELESSD 708
Query: 410 DSAF---------PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGS 460
DS P FE Q+ V V +C ++ P P+V+W +G+ +R EG
Sbjct: 709 DSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALR-SEGR 767
Query: 461 IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE--------------- 505
+ + + H L L +AR D+G+Y TA+N GQ +C+ +L V
Sbjct: 768 LLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSD 827
Query: 506 ------------------RLAVMEVAPS---------------FSSVLKDCAVIEGQDFV 532
R M+ +PS F L D +V EGQD +
Sbjct: 828 EEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVI 887
Query: 533 LQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAELHIQDALPEDHGTYTCLAENA 588
+ V+G P P ++WL N QP++ + E G+ L I A D G YTC A N
Sbjct: 888 MSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNE 947
Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
G C A + V SR L P L D+ V G V+G
Sbjct: 948 YGARQCEARLEVRAHPESRSLAVLAP--------------LQDVDVGAGEMALFECLVAG 993
Query: 649 NPPPEVIWLHNGNEIQESE---DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVR 705
EV WL G +Q + HF+ G + L + V +D+G YTC+ + E+
Sbjct: 994 PTDVEVDWLCRGRLLQPALLKCKMHFD--GRKCKLLLTSVHEDDSGVYTCKLSTAKDELT 1051
Query: 706 TQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
A LTV+ P F V G++ C I+G P P V W G + +++
Sbjct: 1052 CSARLTVR---PSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPM-EES 1107
Query: 766 GHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 818
+ + Q+ + +L + V G Y + N G+ C L ++ A
Sbjct: 1108 ENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAA 1160
Score = 144 bits (364), Expect = 6e-34
Identities = 98/356 (27%), Positives = 168/356 (47%), Gaps = 58/356 (16%)
Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLH 1517
+++SDFYDI + +G G F + R+VE+ + +A KF + AK K + R+E ++ L
Sbjct: 1595 RRLSDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPS-QAKPKASARREARLLARLQ 1653
Query: 1518 HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIH 1577
H ++ +AFE + +V+V E+ + EL ERI + + E E YMRQ+ EG+ Y+H
Sbjct: 1654 HDCVLYFHEAFERRRGLVIVTELCTE-ELLERIARKP-TVCESEIRAYMRQVLEGIHYLH 1711
Query: 1578 KQGIVHLDLKPENIMCVNKTG--TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635
+ ++HLD+KPEN++ + ++++ DFG A+ L +GTPEFVAPE++N
Sbjct: 1712 QSHVLHLDVKPENLLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQ 1771
Query: 1636 EPIGYATDMWSIGVICY------------------------------------------- 1652
P+ TD+W +GV+ +
Sbjct: 1772 SPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGF 1831
Query: 1653 -----ILNRLDCT--QCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIG 1705
+ +RL T + L+HPW K E +S D +K +++RR+WQ++ + +
Sbjct: 1832 LIKVLVQDRLRPTAEETLEHPWFKTQAKGAE---VSTDHLKLFLSRRRWQRSQISYKCHL 1888
Query: 1706 RLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFS 1761
L + + + P P + L S D + LE + ++P FS
Sbjct: 1889 VLRPIPELLRAPPERVWVTMPRRPPPSGGLSSSSDSEEEELEELPSVPRPLQPEFS 1944
Score = 124 bits (312), Expect = 7e-28
Identities = 177/805 (21%), Positives = 286/805 (35%), Gaps = 119/805 (14%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F + + ++EG RV+G P+P V+W RN QP+ R + G L
Sbjct: 869 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I A D G YTC+A N GARQ L V S++L
Sbjct: 929 ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAH--------PESRSLA----------- 969
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212
L V V G+M F C + G +V WL LQP+
Sbjct: 970 ----------VLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHF 1019
Query: 213 NGMQV-LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV 271
+G + L + V++DD GVYTC + + + SA L+++ S F R +
Sbjct: 1020 DGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVR--PSLAPLFTRLLE------ 1071
Query: 272 RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP----WAANSQPQPPRESKLESCKD 327
++ LE A +C G+PP W P E+
Sbjct: 1072 ------------DVEVLEGRAARFDCKI---SGTPPPVVTWTHFGCPMEESENLR----- 1111
Query: 328 SPRTAPQTPVLQKTSSSITLQAARVQPEPRAP-GLGVLSPSGE---------ERKRPAPP 377
L++ +L A V E + ++ G+ E R A
Sbjct: 1112 ----------LRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAAS 1161
Query: 378 RPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS-AFPKFESKPQSQEVKENQTVKFRCE 436
P++ + P + + P +G+ + + P F Q EV + C+
Sbjct: 1162 GPSSKLEKMPSIPEE-----------PEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQ 1210
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGS-IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQ 495
V+G+P P ++WF G ++ + + Y D H L + +G Y +N G+
Sbjct: 1211 VTGLPYPTISWFHNGHRIQSSDDRRMTQYRDV--HRLVFPAVGPQHAGVYKSVIANKLGK 1268
Query: 496 LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ 555
+C L V +V P + G+ L + P + ++ +
Sbjct: 1269 AAC-----YAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWN----PPRSLDMAIDPDSLT 1319
Query: 556 YARSTCEAGVAE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE--YL 612
Y G + + L E T L + + K S SE L
Sbjct: 1320 YTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQL 1379
Query: 613 LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 672
L P+ AP L + V++G ++TV + + +V+W + E+ +E
Sbjct: 1380 LEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYE 1438
Query: 673 QR---GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729
Q+ L I V D G TC A N G L + E P F S
Sbjct: 1439 LSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-----PRFESIMED 1493
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
V G++ + + G P P + W +D + L ++ H + E+ +LV+
Sbjct: 1494 VEVGAGETARFAVVVEGKPLPDIMWYKD-EVLLTESSHVSFVYEENECSLVVLSTGAQDG 1552
Query: 790 GQYEILLKNRVGECSCQVSLMLQNS 814
G Y +N GE SC+ L + ++
Sbjct: 1553 GVYTCTAQNLAGEVSCKAELAVHSA 1577
Score = 120 bits (301), Expect = 1e-26
Identities = 141/591 (23%), Positives = 211/591 (35%), Gaps = 81/591 (13%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91
AP F ++ + EG A+F+ ++ G P P VTW G P+ L G SL
Sbjct: 1063 APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQD-GGLHSL 1121
Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVET 151
I V ED G Y A N G + +L VE G S L S P
Sbjct: 1122 HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGP---SSKLEKMPSIPEEPE 1178
Query: 152 RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE 211
+ + P F L + V + C++TG P P ++W +Q S +++
Sbjct: 1179 QGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQ 1238
Query: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV 271
+ L V GVY ++ N GKA+ A L +V + D
Sbjct: 1239 YRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHL-----------YVTDVVPGPPDG 1287
Query: 272 RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRT 331
+V V + L W PPR + DS
Sbjct: 1288 APQVVAVTGRMVTLT---------------------W------NPPRSLDMAIDPDSLTY 1320
Query: 332 APQTPVLQKTSSSITLQAARVQPEPRAPGLG--------VLSPSGEERKRPAPPRPATFP 383
Q VL + + R +P A GL VLS + + +P+PP
Sbjct: 1321 TVQHQVLGSDQWTALVTGLR-EPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPP------ 1373
Query: 384 TRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKP 443
S+ V ++ G P KP V E Q + +
Sbjct: 1374 -------SEPV-------QLLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQ 1419
Query: 444 EVAWFLEGTPVRRQEGSIEVYEDAGSHY-LCLLKARTRDSGTYSCTASNAQGQLSCSWTL 502
V G + + G E+ + Y L + + RD G +CTA N G +CS TL
Sbjct: 1420 VVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTL 1479
Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARS 559
++ AP F S+++D V G+ V G P+P I W + + +
Sbjct: 1480 ELAE------APRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSF 1533
Query: 560 TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
E L + +D G YTC A+N G+VSC A + VH +++ + E
Sbjct: 1534 VYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVE 1584
Score = 117 bits (293), Expect = 1e-25
Identities = 91/331 (27%), Positives = 147/331 (44%), Gaps = 25/331 (7%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
AP F + L+DV V EG+ C++S PP + WT G ++ ++ + L Q+G L S+
Sbjct: 1063 APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLH 1122
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
I ED GLY A N GQA CS Q+ V++ P + P S L
Sbjct: 1123 IAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEE---------PRTAASGPSSKL------ 1167
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
E ++ ++P + ++ P ++ +D +V + L +VTG T +W
Sbjct: 1168 EKMPSIPEEPEQGELERLSI-PDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGH 1226
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD-KPDPPA 1335
+IQ S+ ++ + +L A +H G Y ++ NKLG +L V D P PP
Sbjct: 1227 RIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPD 1286
Query: 1336 GTPCASDIRSSSLTLSW-----YGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSF 1389
G P + +TL+W + D S +Y+++ + W L T R +
Sbjct: 1287 GAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSL--TYTVQHQVLGSDQWTALVTGLREPGW 1344
Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
L ++ FRV + V +S+PS SE
Sbjct: 1345 AATGLRKGVQHIFRVLSTTVKSSSKPSPPSE 1375
Score = 112 bits (281), Expect = 3e-24
Identities = 76/245 (31%), Positives = 123/245 (50%), Gaps = 13/245 (5%)
Query: 1415 PSQESELTTVGEKPEEPKDEVEVS--DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGS 1472
P E T V + P EV S P + T+ QK F + + R
Sbjct: 2918 PEPPPEPTKVTVQSLSPAKEVVSSPGSSPRSSPRPEGTTLRQGPPQKPYTFLEEKAR--- 2974
Query: 1473 GKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKA 1532
G+FG V E T + + K Y+A+ K + QE ++ LHH +++ +A+
Sbjct: 2975 GRFGVVRACRENATGRTFVAKIVP-YAAEGKRRVLQEYEVLRTLHHERIMSLHEAYITPR 3033
Query: 1533 NIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIM 1592
+V++ E EL + D F +E + YM Q+ +G++Y+H ++HLD+KP+N++
Sbjct: 3034 YLVLIAESCGNRELLCGLSDR-FRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLL 3092
Query: 1593 CVNKTGTRIKLIDFGLARRLENAGSLKVL---FGTPEFVAPEVINYEPIGYATDMWSIGV 1649
+K++DFG A+ N +L+ L GT EF+APE++ EPIG ATD+W GV
Sbjct: 3093 LAPDNA--LKIVDFGSAQPY-NPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGV 3149
Query: 1650 ICYIL 1654
+ YI+
Sbjct: 3150 LTYIM 3154
Score = 111 bits (277), Expect = 8e-24
Identities = 110/463 (23%), Positives = 180/463 (38%), Gaps = 52/463 (11%)
Query: 916 KEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPK 975
+E+ RA LQR P+ E R+V +P + P +
Sbjct: 508 EELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDE 567
Query: 976 PATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETL 1035
P P R G + P E + + S+ + + P P + A T
Sbjct: 568 PGRPRSRGPAGRTE--PGEGPQQEVRRRDQFPLTRSRAIQECRSPVP-PPAADPPEARTK 624
Query: 1036 KPMGNAK--PAETLKPM--------GNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTT 1085
P G + PA+ ++ + G A P K+ + E +K ++ + G G
Sbjct: 625 APPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGPE-EDGPWGPW 683
Query: 1086 DNE-KRSESQGT-------------------------APAFKQKLQDVHVAEGKKLLLQC 1119
D RS+ +G AP F+ LQ+V VA G +LL+C
Sbjct: 684 DRRGARSQGKGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKC 743
Query: 1120 QVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQA 1179
++++PP + W +G L++ ++L EG ++ + +A D G Y A N+ GQA
Sbjct: 744 IITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQA 803
Query: 1180 ECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPK------ 1233
C+ +TV ++ +P S PP E T + P K P
Sbjct: 804 TCAASLTVRPGGSTSPFSSPITSDEEYLS--PPEEFPEPGETWPRTPTMKPSPSQNRRSS 861
Query: 1234 ---AAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
+ PP DQ VR G+ V + +V G +W++ R+ ++ + E +E
Sbjct: 862 DTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAE 921
Query: 1291 NG-SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
G +L ILAA + G YT N+ G+RQ + L V P+
Sbjct: 922 GGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPE 964
Score = 107 bits (266), Expect = 1e-22
Identities = 95/352 (26%), Positives = 140/352 (39%), Gaps = 47/352 (13%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH--- 569
AP F L++ V G D +L+C + P P+++W +G ++ E H
Sbjct: 721 APVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLL 780
Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS--------SRKSEYLLP------- 614
+++A D G+Y A N LGQ +C+A +TV S + EYL P
Sbjct: 781 LREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEP 840
Query: 615 --VAPSKPT------------------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
P PT P F L D V +G V M+++V G P P V
Sbjct: 841 GETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVV 900
Query: 655 IWLHNGNEIQ-ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
WL N ++ + F E G L I D G YTC+A N G + +A L V+
Sbjct: 901 SWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVR 960
Query: 714 EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK----ALCKDTGHFE 769
+ ++ + V G+ L C +AG V WL G+ AL K HF+
Sbjct: 961 AHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFD 1020
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 821
+ + L+L V +G Y L E +C L ++ S A R
Sbjct: 1021 GRKCK----LLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTR 1068
Score = 99.8 bits (247), Expect = 2e-20
Identities = 74/244 (30%), Positives = 103/244 (42%), Gaps = 26/244 (10%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC-GIRGTF 89
EAP F +P +N+ + GA + + P PQV+WH++G + S GR LL G R T
Sbjct: 720 EAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHT- 778
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE-GSFAKQLGQPVVSK----TLGDRF 144
L++ D G Y ATN G LTV G P+ S + + F
Sbjct: 779 -LLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEF 837
Query: 145 SAPAVETRP----------------SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
P ET P + PP F L V+EGQ S ++ G P
Sbjct: 838 PEPG-ETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEP 896
Query: 189 QPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247
+P V+WL+ P++P R E + G+ L I + D G YTC VN G A
Sbjct: 897 KPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEAR 956
Query: 248 LSIQ 251
L ++
Sbjct: 957 LEVR 960
Score = 86.7 bits (213), Expect = 2e-16
Identities = 65/231 (28%), Positives = 100/231 (43%), Gaps = 38/231 (16%)
Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
V + P + + A + P +++ + G A FE V G + +V W G+ + LL C
Sbjct: 959 VRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPA---LLKC 1015
Query: 84 GIR---GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
+ L++ +VHE+D G YTC+ + + LTV
Sbjct: 1016 KMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTV----------------- 1058
Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVP 200
RPS+ P F L V V EG+ RF CKI+G P P VTW P
Sbjct: 1059 -----------RPSL----APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCP 1103
Query: 201 LQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
++ S + + + G+ L I V +D G+Y VN G+A SA+L ++
Sbjct: 1104 MEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154
Score = 85.1 bits (209), Expect = 6e-16
Identities = 44/108 (40%), Positives = 61/108 (56%), Gaps = 4/108 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F + D+EV G ARF +EG P P+++W+KD+ + ES H Y+E+ CSL+
Sbjct: 1485 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEEN-ECSLV 1543
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 1862
+ D YTC A N GE +C AEL V +T E EG GE+E+
Sbjct: 1544 VLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDED 1591
Score = 78.2 bits (191), Expect = 7e-14
Identities = 41/97 (42%), Positives = 59/97 (60%), Gaps = 1/97 (1%)
Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
+P + P F++ + D+EV+EG AARFDCKI G P P V W + ES + ++ D G
Sbjct: 1059 RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQD-GG 1117
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
SL I+ V +D+ Y AVN+ G+A C+A+L VE
Sbjct: 1118 LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154
Score = 64.7 bits (156), Expect = 8e-10
Identities = 59/230 (25%), Positives = 85/230 (36%), Gaps = 37/230 (16%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH--RNGQPITSGGRFLLDCGIR 86
L EAPA + P + + EG A + E QV W R G + L
Sbjct: 1386 LEEAPAMLDKPDIVYVVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYELSQPDD 1444
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
+ L I V D G TC A N G + +V L + +
Sbjct: 1445 DQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-------------------- 1484
Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
P+F + + V V G+ RF+ + G+P P + W K V L S+
Sbjct: 1485 --------------PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSH 1530
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256
VS + L + D GVYTC N +G+ S AEL++ +A
Sbjct: 1531 VSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTA 1580
Score = 60.8 bits (146), Expect = 1e-08
Identities = 47/165 (28%), Positives = 71/165 (43%), Gaps = 18/165 (10%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ--PIQYARSTCEAGVAELHI 570
AP F LK+ AV G D L+ V GTP P + W +GQ P +C L +
Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSC------LWL 95
Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
+ +D G Y+C+A+N G+ SC A +TV E S +E ++ + T + L+
Sbjct: 96 RRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAED--DISDVQGTQRLELRDDG 153
Query: 631 DLKVMDGSQVTMT--------VQVSGNPPPEVIWLHNGNEIQESE 667
G T+ V+G +V W +G + E E
Sbjct: 154 AFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQE 198
Score = 59.3 bits (142), Expect = 3e-08
Identities = 52/252 (20%), Positives = 87/252 (34%), Gaps = 47/252 (18%)
Query: 1088 EKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF-IIL 1146
E R+ + + A LQDV V G+ L +C V+ + W G+ L+ +
Sbjct: 958 EVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKM 1017
Query: 1147 SQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
+G C + + +D G+Y C + CS ++TV
Sbjct: 1018 HFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTV------------------- 1058
Query: 1207 KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQP 1266
+ ++ P + ED +V G + K++GT P
Sbjct: 1059 --------------------------RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPP 1092
Query: 1267 ITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT 1326
TW F ++ESE++++ L I E G Y + N G L
Sbjct: 1093 PVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQL- 1151
Query: 1327 VVDKPDPPAGTP 1338
V++P A P
Sbjct: 1152 YVEEPRTAASGP 1163
Score = 57.0 bits (136), Expect = 2e-07
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Query: 1720 KSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1779
K PTSP +LES +D + A E+P P F ++++ V G+ C
Sbjct: 693 KGRRARPTSP----ELESSDDSYVS-----AGEEPLEAPVFEIPLQNVVVAPGADVLLKC 743
Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
I P P+V W KD ++R + + + + +L++ + D Y A N LG+
Sbjct: 744 IITANPPPQVSWHKDGSALRSEGRLLLRAEGERH-TLLLREARAADAGSYMATATNELGQ 802
Query: 1840 ATCTAELIV 1848
ATC A L V
Sbjct: 803 ATCAASLTV 811
Score = 57.0 bits (136), Expect = 2e-07
Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 13/228 (5%)
Query: 972 PPPKPATPDFRSVLG--GKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 1029
PPP+ + S L G+ L AE + A+A ++ ++ A +G A
Sbjct: 749 PPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATAT-----NELGQA 803
Query: 1030 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1089
A +L +P + P + + + EE + + + N +
Sbjct: 804 TCAASL----TVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRR 859
Query: 1090 RSESQGTAP-AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
S++ AP FK L D V EG+ +++ +V +P + W N + ++ + +
Sbjct: 860 SSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEE 919
Query: 1149 -EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195
EG LC + I A D G Y C A N+ G +C ++ V P S +
Sbjct: 920 AEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRS 967
Score = 55.1 bits (131), Expect = 6e-07
Identities = 32/96 (33%), Positives = 42/96 (43%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F ++ D V EG +++G P P V W ++ Q +R + + E G C L
Sbjct: 869 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
I D YTCKAVN G C A L V E
Sbjct: 929 ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPE 964
Score = 53.1 bits (126), Expect = 2e-06
Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
AP+FL+ L + V GS V + V VSG P P + W +G + L
Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAP-------EPSCLW 94
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
++ +D G Y+C A N G +AVLTV E D
Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGD 130
Score = 53.1 bits (126), Expect = 2e-06
Identities = 41/188 (21%), Positives = 74/188 (39%), Gaps = 4/188 (2%)
Query: 343 SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAA 399
+ + QA P + G + SG + R + P + GL ++ +
Sbjct: 2509 NQLAAQAGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLSASVQ 2568
Query: 400 NRRIPMEGQRDSAFPK-FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE 458
+ +S FP F K + Q + E + C + P P ++W + +R +
Sbjct: 2569 EELGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEP 2628
Query: 459 GSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSS 518
I V G L + +A R +G Y C+A+N G ++ S T+ V R+ P
Sbjct: 2629 SVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVPQ 2688
Query: 519 VLKDCAVI 526
+D A++
Sbjct: 2689 TYQDTALV 2696
Score = 53.1 bits (126), Expect = 2e-06
Identities = 51/178 (28%), Positives = 79/178 (44%), Gaps = 14/178 (7%)
Query: 1017 AQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSASKEELKKDVKND 1074
A +G P + +E G++ P E+ + G ++P ++ K S L V+ +
Sbjct: 2512 AAQAGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKD-KGLSPPNLSASVQEE 2570
Query: 1075 VNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN 1134
+ GH RSES P F KL+D + EG+ L C ++ P I W +
Sbjct: 2571 L----GHQYV-----RSESD-FPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKD 2620
Query: 1135 GKTLKTT-KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
K+L++ II+S + +SI +A GLY+C A N G SC V V P
Sbjct: 2621 KKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVP 2678
Score = 52.4 bits (124), Expect = 4e-06
Identities = 55/209 (26%), Positives = 80/209 (38%), Gaps = 45/209 (21%)
Query: 368 GEERKRPAPPRPATFPTR-QPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVK 426
GE+ APP P P R + G G V+ A P F ++ V
Sbjct: 9 GEDAGTRAPPSPGVPPKRAKVGAGGGAPVAVAGA-------------PVFLRPLKNAAVC 55
Query: 427 ENQTVKFRCEVSGIPKPEVAWFLEGT--PVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V+ R VSG P+P + WF +G P E S L L + +D+G
Sbjct: 56 AGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSC----------LWLRRCGAQDAGV 105
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE------------GQDFV 532
YSC A N +G+ SC L V + E A S ++ +E G D +
Sbjct: 106 YSCMAQNERGRASCEAVLTVLEVGDSETAEDDISDVQGTQRLELRDDGAFSTPTGGSDTL 165
Query: 533 L-------QCSVRGTPVPRITWLLNGQPI 554
+ SV GT +++W +GQ +
Sbjct: 166 VGTSLDTPPTSVTGTSEEQVSWWGSGQTV 194
Score = 49.7 bits (117), Expect = 3e-05
Identities = 26/94 (27%), Positives = 43/94 (45%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
AP F+ ++DV V G+ V P I+W + L + + E + CS+
Sbjct: 1484 APRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLV 1543
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
+ +D G+Y C A+N AG+ C ++ V A
Sbjct: 1544 VLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSA 1577
Score = 49.3 bits (116), Expect = 4e-05
Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 11/161 (6%)
Query: 1699 NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLES-EEDVSQAFLEAVAEEKPHVK 1757
+AV G+ A + R +++G P+S L EK+ S E+ Q LE ++
Sbjct: 1137 SAVNTHGQAHCSAQLYVEEPRTAASG-PSSKL--EKMPSIPEEPEQGELERLSI------ 1187
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F + ++DLEV A +C++ G P P + WF + I+ S ++ D + L+
Sbjct: 1188 PDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVH-RLV 1246
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1858
V Y N LG+A C A L V + G +G
Sbjct: 1247 FPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDG 1287
Score = 48.5 bits (114), Expect = 6e-05
Identities = 26/85 (30%), Positives = 43/85 (50%)
Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
++D++V G A F+C + G D EV W + ++ + + + C L+++ V
Sbjct: 974 LQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHE 1033
Query: 1824 DDDAKYTCKAVNSLGEATCTAELIV 1848
DD YTCK + E TC+A L V
Sbjct: 1034 DDSGVYTCKLSTAKDELTCSARLTV 1058
Score = 48.1 bits (113), Expect = 8e-05
Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 7/124 (5%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
K L P +S ++ + V + + PP F KL V+ EG+ C P
Sbjct: 2556 KGLSPPNLSASVQEELGHQYVRSE----SDFPPVFHIKLKDQVLLEGEAATLLCLPAACP 2611
Query: 189 QPQVTWLKGNVPL--QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
P ++W+K L +PS + VS K+G Q+L I + G+Y C N G + S
Sbjct: 2612 APHISWMKDKKSLRSEPSV-IIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSC 2670
Query: 247 ELSI 250
+++
Sbjct: 2671 TVAV 2674
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F + +++ V GS R + G P P + WF+D Q + + +C +
Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPA-------PEPSCLWL 95
Query: 1818 ISDVCGDDDA-KYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
CG DA Y+C A N G A+C A L V +E G+ E E++
Sbjct: 96 RR--CGAQDAGVYSCMAQNERGRASCEAVLTV--LEVGDSETAEDD 137
Score = 46.6 bits (109), Expect = 2e-04
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 4/91 (4%)
Query: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS----TCEAGVAELH 569
P F LKD ++EG+ L C P P I+W+ + + ++ S +C+ G L
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643
Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
I A G Y C A N LG ++ S V V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
Score = 45.1 bits (105), Expect = 7e-04
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 7/101 (6%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
AP F + L++ V G + L+ VS P ++ W +G+ L + E S +
Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAP-----APEPSC--LW 94
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK 1197
+ + +D G+Y C+A+N+ G+A C +TV + SE +
Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAE 135
Score = 45.1 bits (105), Expect = 7e-04
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 5/103 (4%)
Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR--FLLDC 83
++ L EAP F ++ + G TA+F V G P P + W+++ +T F+ +
Sbjct: 1478 TLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYE- 1536
Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
SLV+ + +D G YTC A N +G EL V +
Sbjct: 1537 --ENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSA 1577
Score = 44.7 bits (104), Expect = 9e-04
Identities = 28/91 (30%), Positives = 38/91 (41%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F ++D ++EG AA C P P + W KD +S+R I +DG L
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
I Y C A N LG T + + V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
Score = 42.7 bits (99), Expect = 0.003
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 8/92 (8%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91
AP F+ P +N + G+ + V G P+P + W R+GQ LL L
Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQ--------LLPAPAPEPSCL 93
Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ +D G Y+C A N G LTV
Sbjct: 94 WLRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125
Score = 42.7 bits (99), Expect = 0.003
Identities = 60/258 (23%), Positives = 101/258 (39%), Gaps = 21/258 (8%)
Query: 1176 AGQAECSCQVTVDDAPASENTKAP-EMKSR---------RPKSSLPPVLGTESDATVKKK 1225
AG S + +A A+ + AP E +SR + K PP L A+V+++
Sbjct: 2515 AGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLS----ASVQEE 2570
Query: 1226 PAPK-TPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
+ ++ PP +DQ + GE+ L +WMK +K ++ +
Sbjct: 2571 LGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSV 2630
Query: 1285 KVENSENGSKL-TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
+ + ++G +L +I A + H G Y N LGS + + V P A
Sbjct: 2631 IIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVPQTY 2690
Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKF 1402
+ ++L L G S A +Y++E W +++ +NV L +F
Sbjct: 2691 QDTALVLWKPGDS----RAPCTYTLERRVDGESVWHPVSSGIPDCYYNVTHLPVGVTVRF 2746
Query: 1403 RVRAINVYGTSEPSQESE 1420
RV N G S SE
Sbjct: 2747 RVACANRAGQGPFSNSSE 2764
Score = 40.0 bits (92), Expect = 0.021
Identities = 26/93 (27%), Positives = 36/93 (38%)
Query: 1235 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSK 1294
A P+ ED +V AGE+ V G W K + ES H+ EN
Sbjct: 1482 AEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECS 1541
Query: 1295 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
L +L+ + G YT +N G + L V
Sbjct: 1542 LVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 1574
Score = 38.9 bits (89), Expect = 0.047
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 9/91 (9%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLE 219
P F L V G R ++G PQP + W + G + P+ S L
Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSC--------LW 94
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ D GVY+C+ N G+AS A L++
Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125
Score = 37.7 bits (86), Expect = 0.11
Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 8/89 (8%)
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
P F+ ++ G V + ++G P P++ W RDG+ L + L
Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPA--------PEPSCLW 94
Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSL 809
L++ AG Y + +N G SC+ L
Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVL 123
Score = 34.3 bits (77), Expect = 1.2
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 2/91 (2%)
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
P F K + G++ + C A P P + W++D K+L + V + L
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643
Query: 781 LKKVQPWHAGQYEILLKNRVGE--CSCQVSL 809
+ + HAG YE N +G SC V++
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
Score = 33.1 bits (74), Expect = 2.6
Identities = 30/141 (21%), Positives = 54/141 (38%), Gaps = 20/141 (14%)
Query: 1219 DATVKKKPAPKTPPKAAM-------------PPQIIQFPEDQKVRAGESVELFGKVTGTQ 1265
DA + P+P PPK A P ++ ++ V AG V L V+GT
Sbjct: 11 DAGTRAPPSPGVPPKRAKVGAGGGAPVAVAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTP 70
Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325
+ W + + + + S L + + G Y+ + +N+ G + L
Sbjct: 71 QPSLRWFRDGQLLPAP-------APEPSCLWLRRCGAQDAGVYSCMAQNERGRASCEAVL 123
Query: 1326 TVVDKPDPPAGTPCASDIRSS 1346
TV++ D SD++ +
Sbjct: 124 TVLEVGDSETAEDDISDVQGT 144
Score = 32.0 bits (71), Expect = 5.8
Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 13/101 (12%)
Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH--FQIDYDEDGNCSLIISDVCGDDD 1826
VVEG A + + +VVW ++ E+R +++ +D L I V D
Sbjct: 1401 VVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDM 1459
Query: 1827 AKYTCKAVNSLGEATCTA----------ELIVETMEEGEGE 1857
TC A N G TC+ E I+E +E G GE
Sbjct: 1460 GALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVGAGE 1500
Score = 32.0 bits (71), Expect = 5.8
Identities = 19/91 (20%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLC 681
P+F L D +++G T+ + P P + W+ + ++ E + + L
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
I G Y C A N G + + + V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
Length = 2986
Score = 185 bits (469), Expect = 4e-46
Identities = 156/588 (26%), Positives = 244/588 (41%), Gaps = 98/588 (16%)
Query: 1194 ENTKAPEMKS-RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMP---PQIIQ--FPE-- 1245
ENT E R+PK L + + + ++ P +M P IQ PE
Sbjct: 2415 ENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFL 2474
Query: 1246 ----DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK----VENSENGS-KLT 1296
D G++V L KV G T TW + I ++++ V + ++G L
Sbjct: 2475 VPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLK 2534
Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1356
I + G YT + N G+ + V P P P A + +S+ L W S
Sbjct: 2535 ICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAP-NRPIAQERSCTSVILRWLPPS 2593
Query: 1357 YDGGSAVQSYSIEIWDSANKTWKE-LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
G + Y++E + ++ W++ +A+ T ++DL P Y+FRV A N +G S P
Sbjct: 2594 STGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLP 2653
Query: 1416 SQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRT--VTINTEQKVSDFYDIEERLGSG 1473
S+ SE + PE D TI+ ++ Y +G G
Sbjct: 2654 SEPSEFVRL--------------------PEYDAAADGATISWKENFDSAYTELNEIGRG 2693
Query: 1474 KFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN 1533
+F V + + K TRK A KF K+KE E +++ L HP+ + D +E +
Sbjct: 2694 RFSIVKKCIHKATRKDVAVKFVSK-KMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTS 2752
Query: 1534 IVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMC 1593
+++LE++ G L + +++ D EL E + Y+R I E ++Y+H + HLD+KPEN++
Sbjct: 2753 YILILELMDDGRLLDYLMNHD-ELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLI 2811
Query: 1594 VNKTGT-RIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1652
+ R+KLID A ++ + L G PEF APEVI P+ TD+WSIGV+ Y
Sbjct: 2812 DLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTY 2871
Query: 1653 IL---------------------------------------------------NRLDCTQ 1661
++ R
Sbjct: 2872 VMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAAT 2931
Query: 1662 CLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSS 1709
CLQHPWL + L R+ ++ RRK Q N VR I + S
Sbjct: 2932 CLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQ---NDVRPIPNVKS 2976
Score = 71.2 bits (173), Expect = 9e-12
Identities = 45/122 (36%), Positives = 58/122 (47%), Gaps = 18/122 (14%)
Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--------QYARST 560
+ EVAP F L D + G +LQC V G P P ITW Q I Y S+
Sbjct: 2466 IQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSS 2525
Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 620
C++G L I + +P+D G YTC+A N G S SA V V +P AP++P
Sbjct: 2526 CDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG----------VPAAPNRP 2575
Query: 621 TA 622
A
Sbjct: 2576 IA 2577
Score = 60.1 bits (144), Expect = 2e-08
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL----QPSARVS 208
P+ E P+F L V G CK+ GRP+P +TW + + SA +
Sbjct: 2463 PNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYT 2522
Query: 209 VSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA-NRSFVRETKA 266
VS +G L+I + D G+YTC+ N G S SA + +QG+ +A NR +E
Sbjct: 2523 VSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSC 2582
Query: 267 TNSDVR 272
T+ +R
Sbjct: 2583 TSVILR 2588
Score = 58.9 bits (141), Expect = 4e-08
Identities = 58/241 (24%), Positives = 89/241 (36%), Gaps = 37/241 (15%)
Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNA-KPAETLKPMGNAKPAETLKPMGNAKPD 1056
S E + AV QP+ P P L P+ A AE+ G+ K
Sbjct: 2343 SQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAAESSD--GSIKKS 2400
Query: 1057 ---ENLKSASKEELKKDVKN---------DVNCKRGHAGTTDNEKRSES----------- 1093
L+ + E++ KN D+ + T++ + SE
Sbjct: 2401 CSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEI 2460
Query: 1094 ------QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK----- 1142
Q AP F L DV G ++LQC+V P TI W + + T
Sbjct: 2461 LNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSAT 2520
Query: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202
+ + S + ++ I +P+D G+Y C+A ND G S V V PA+ N + +
Sbjct: 2521 YTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQER 2580
Query: 1203 S 1203
S
Sbjct: 2581 S 2581
Score = 50.1 bits (118), Expect = 2e-05
Identities = 59/224 (26%), Positives = 96/224 (42%), Gaps = 30/224 (13%)
Query: 598 VTVHEKKSSRKSEY----------LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
V+V E SS +SE +L + AP FL L D+ + G V + +V
Sbjct: 2436 VSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVC 2495
Query: 648 GNPPPEVIWLHNGNEIQESEDFHFEQRGT-----QHSLCIQEVFPEDTGTYTCEAWNSAG 702
G P P + W I ++++ + + +L I + P+D+G YTC A N G
Sbjct: 2496 GRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHG 2555
Query: 703 EVRTQAVLTVQ-EPHDGTQPWFISKPRSVTAS----LGQSVLISCAIAGDPFPTVHWLRD 757
T A + VQ P +P I++ RS T+ L S +C I+G TV + +
Sbjct: 2556 TTSTSATVKVQGVPAAPNRP--IAQERSCTSVILRWLPPSSTGNCTISG---YTVEYREE 2610
Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
G + + + V D + LV++ + P Q+ + N G
Sbjct: 2611 GSQIWQQS----VASTLDTY-LVIEDLSPGCPYQFRVSASNPWG 2649
Score = 45.8 bits (107), Expect = 4e-04
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI----TSGGRFLLDCGIRG 87
AP F++P ++ G T + +V G P+P +TW Q I S + + G
Sbjct: 2470 APEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSG 2529
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
+L I + +D G YTC ATN G + + V+G
Sbjct: 2530 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG 2567
Score = 45.4 bits (106), Expect = 5e-04
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 4/98 (4%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD----ED 1811
V P F + D+ + G CK+ G P P + W DQ+I ++ + Y +
Sbjct: 2469 VAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDS 2528
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
G +L I ++ D YTC A N G + +A + V+
Sbjct: 2529 GEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQ 2566
Score = 44.7 bits (104), Expect = 9e-04
Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 430 TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYE----DAGSHYLCLLKARTRDSGTY 485
TV +C+V G PKP + W + + S Y D+G L + +DSG Y
Sbjct: 2487 TVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIY 2546
Query: 486 SCTASNAQGQLSCSWTLQVE 505
+C A+N G S S T++V+
Sbjct: 2547 TCIATNDHGTTSTSATVKVQ 2566
Score = 35.0 bits (79), Expect = 0.68
Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 6/101 (5%)
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-----NED 775
P F+ VT LG +V++ C + G P PT+ W + + DT + +
Sbjct: 2471 PEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNIL-DTDNSSATYTVSSCDSG 2529
Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
TL + + P +G Y + N G S ++ +Q A
Sbjct: 2530 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPA 2570
>gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]
Length = 1289
Score = 185 bits (469), Expect = 4e-46
Identities = 156/588 (26%), Positives = 244/588 (41%), Gaps = 98/588 (16%)
Query: 1194 ENTKAPEMKS-RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMP---PQIIQ--FPE-- 1245
ENT E R+PK L + + + ++ P +M P IQ PE
Sbjct: 718 ENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFL 777
Query: 1246 ----DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK----VENSENGS-KLT 1296
D G++V L KV G T TW + I ++++ V + ++G L
Sbjct: 778 VPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLK 837
Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1356
I + G YT + N G+ + V P P P A + +S+ L W S
Sbjct: 838 ICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAP-NRPIAQERSCTSVILRWLPPS 896
Query: 1357 YDGGSAVQSYSIEIWDSANKTWKE-LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
G + Y++E + ++ W++ +A+ T ++DL P Y+FRV A N +G S P
Sbjct: 897 STGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLP 956
Query: 1416 SQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRT--VTINTEQKVSDFYDIEERLGSG 1473
S+ SE + PE D TI+ ++ Y +G G
Sbjct: 957 SEPSEFVRL--------------------PEYDAAADGATISWKENFDSAYTELNEIGRG 996
Query: 1474 KFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN 1533
+F V + + K TRK A KF K+KE E +++ L HP+ + D +E +
Sbjct: 997 RFSIVKKCIHKATRKDVAVKFVSK-KMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTS 1055
Query: 1534 IVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMC 1593
+++LE++ G L + +++ D EL E + Y+R I E ++Y+H + HLD+KPEN++
Sbjct: 1056 YILILELMDDGRLLDYLMNHD-ELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLI 1114
Query: 1594 VNKTGT-RIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1652
+ R+KLID A ++ + L G PEF APEVI P+ TD+WSIGV+ Y
Sbjct: 1115 DLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTY 1174
Query: 1653 IL---------------------------------------------------NRLDCTQ 1661
++ R
Sbjct: 1175 VMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAAT 1234
Query: 1662 CLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSS 1709
CLQHPWL + L R+ ++ RRK Q N VR I + S
Sbjct: 1235 CLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQ---NDVRPIPNVKS 1279
Score = 71.2 bits (173), Expect = 9e-12
Identities = 45/122 (36%), Positives = 58/122 (47%), Gaps = 18/122 (14%)
Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--------QYARST 560
+ EVAP F L D + G +LQC V G P P ITW Q I Y S+
Sbjct: 769 IQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSS 828
Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 620
C++G L I + +P+D G YTC+A N G S SA V V +P AP++P
Sbjct: 829 CDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG----------VPAAPNRP 878
Query: 621 TA 622
A
Sbjct: 879 IA 880
Score = 60.1 bits (144), Expect = 2e-08
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL----QPSARVS 208
P+ E P+F L V G CK+ GRP+P +TW + + SA +
Sbjct: 766 PNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYT 825
Query: 209 VSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA-NRSFVRETKA 266
VS +G L+I + D G+YTC+ N G S SA + +QG+ +A NR +E
Sbjct: 826 VSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSC 885
Query: 267 TNSDVR 272
T+ +R
Sbjct: 886 TSVILR 891
Score = 58.9 bits (141), Expect = 4e-08
Identities = 58/241 (24%), Positives = 89/241 (36%), Gaps = 37/241 (15%)
Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNA-KPAETLKPMGNAKPAETLKPMGNAKPD 1056
S E + AV QP+ P P L P+ A AE+ G+ K
Sbjct: 646 SQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAAESSD--GSIKKS 703
Query: 1057 ---ENLKSASKEELKKDVKN---------DVNCKRGHAGTTDNEKRSES----------- 1093
L+ + E++ KN D+ + T++ + SE
Sbjct: 704 CSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEI 763
Query: 1094 ------QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK----- 1142
Q AP F L DV G ++LQC+V P TI W + + T
Sbjct: 764 LNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSAT 823
Query: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202
+ + S + ++ I +P+D G+Y C+A ND G S V V PA+ N + +
Sbjct: 824 YTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQER 883
Query: 1203 S 1203
S
Sbjct: 884 S 884
Score = 50.1 bits (118), Expect = 2e-05
Identities = 59/224 (26%), Positives = 96/224 (42%), Gaps = 30/224 (13%)
Query: 598 VTVHEKKSSRKSEY----------LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
V+V E SS +SE +L + AP FL L D+ + G V + +V
Sbjct: 739 VSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVC 798
Query: 648 GNPPPEVIWLHNGNEIQESEDFHFEQRGT-----QHSLCIQEVFPEDTGTYTCEAWNSAG 702
G P P + W I ++++ + + +L I + P+D+G YTC A N G
Sbjct: 799 GRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHG 858
Query: 703 EVRTQAVLTVQ-EPHDGTQPWFISKPRSVTAS----LGQSVLISCAIAGDPFPTVHWLRD 757
T A + VQ P +P I++ RS T+ L S +C I+G TV + +
Sbjct: 859 TTSTSATVKVQGVPAAPNRP--IAQERSCTSVILRWLPPSSTGNCTISG---YTVEYREE 913
Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
G + + + V D + LV++ + P Q+ + N G
Sbjct: 914 GSQIWQQS----VASTLDTY-LVIEDLSPGCPYQFRVSASNPWG 952
Score = 45.8 bits (107), Expect = 4e-04
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI----TSGGRFLLDCGIRG 87
AP F++P ++ G T + +V G P+P +TW Q I S + + G
Sbjct: 773 APEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSG 832
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
+L I + +D G YTC ATN G + + V+G
Sbjct: 833 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG 870
Score = 45.4 bits (106), Expect = 5e-04
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 4/98 (4%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD----ED 1811
V P F + D+ + G CK+ G P P + W DQ+I ++ + Y +
Sbjct: 772 VAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDS 831
Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
G +L I ++ D YTC A N G + +A + V+
Sbjct: 832 GEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQ 869
Score = 44.7 bits (104), Expect = 9e-04
Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 430 TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYE----DAGSHYLCLLKARTRDSGTY 485
TV +C+V G PKP + W + + S Y D+G L + +DSG Y
Sbjct: 790 TVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIY 849
Query: 486 SCTASNAQGQLSCSWTLQVE 505
+C A+N G S S T++V+
Sbjct: 850 TCIATNDHGTTSTSATVKVQ 869
Score = 35.0 bits (79), Expect = 0.68
Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 6/101 (5%)
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-----NED 775
P F+ VT LG +V++ C + G P PT+ W + + DT + +
Sbjct: 774 PEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNIL-DTDNSSATYTVSSCDSG 832
Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
TL + + P +G Y + N G S ++ +Q A
Sbjct: 833 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPA 873
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 179 bits (454), Expect = 2e-44
Identities = 185/766 (24%), Positives = 292/766 (38%), Gaps = 155/766 (20%)
Query: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
E R G P PQ+ W +NG P+ L G ++ A D YTC A+N +
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSSHIRLLAA--GQVIRIVRA-QVSDVAVYTCVASNRA 3419
Query: 113 GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLG--RV 170
G L V FA PP +G +
Sbjct: 3420 GVDNKHYNLQV---FA-------------------------------PPNMDNSMGTEEI 3445
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
V +G +C G P P + WL+ PL A ++VS +GM VL++ +D G
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST-HGM-VLQLLKAETEDSGK 3503
Query: 231 YTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
YTC+ N +G+ S L + + S+ +E++ +++ +L +
Sbjct: 3504 YTCIASNEAGEVSKHFILKV----------LEPPHINGSEEHEEISVIVNNPLELTCI-- 3551
Query: 291 AAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
A+ P P K+ KD R PQT +Q L+ +
Sbjct: 3552 -------------------ASGIPAP----KMTWMKDG-RPLPQTDQVQTLGGGEVLRIS 3587
Query: 351 RVQPEPRAPGLGVLS-PSGEERKRPAPPRPATFPTR---QPGLGSQDVVSKAANRRIPME 406
Q E + S P+G++ K + R P + D
Sbjct: 3588 TAQVEDTGRYTCLASSPAGDDDKE--------YLVRVHVPPNIAGTD------------- 3626
Query: 407 GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYED 466
+P+ V N+ V C+ +P P + W G R + + V
Sbjct: 3627 ------------EPRDITVLRNRQVTLECKSDAVPPPVITWLRNG---ERLQATPRVRIL 3671
Query: 467 AGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526
+G YL + A D+ Y+C ASN G+ + + L V V P+ + ++
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVIL 3725
Query: 527 EGQDFVLQCSVRGTPVPRITWLLNGQPI--QYAR-STCEAGVAELHIQDALPEDHGTYTC 583
+ VL+C G P PRITW +G + +AR S E G LHIQ A D G Y C
Sbjct: 3726 LNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 3783
Query: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
+A NA G R+ + + V PS P +++ V+ Q T+
Sbjct: 3784 MATNAAGT-------------DRRRIDLQVHVPPSIAPGP------TNMTVIVNVQTTLA 3824
Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
+ +G P P + W NG+ + ++ + + + SL I +DT TY C N AG+
Sbjct: 3825 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 3884
Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
+ LTVQ P P +P + +I+C +G PFP++HW ++G L
Sbjct: 3885 DKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLP 3939
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
+ +L + + L Q HAG+Y + +N G V+L
Sbjct: 3940 RGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTL 3982
Score = 152 bits (385), Expect = 2e-36
Identities = 185/803 (23%), Positives = 298/803 (37%), Gaps = 129/803 (16%)
Query: 60 PEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P P +TW ++G P+ + L I +D G+YTCEATN +G +
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSIS---ENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNY 2187
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
+ + P+I G + +L ++ V EG +
Sbjct: 2188 NVNIW--------------------------VPPNIGG------SDELTQLTVIEGNLIS 2215
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
C+ +G P P + W K P+ + V +G + L+I + D +Y+C+ N +
Sbjct: 2216 LLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVA 2275
Query: 240 GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKS----- 294
G A L + ++R T TNS T +I K SLE +
Sbjct: 2276 GTAKKEYNLQV---------YIRPT-ITNSG--SHPTEIIVTRGKSISLECEVQGIPPPT 2323
Query: 295 ---------------------------KNCSSPQRGGSPPWAANSQPQPPRESKLE---- 323
KN G A N ++ L
Sbjct: 2324 VTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2383
Query: 324 -SCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLG---VLSPSGEERKRPAPPRP 379
S + R+ V++K S S+T +A+ + P P +S S R
Sbjct: 2384 PSIIGNHRSPENISVVEKNSVSLTCEASGI-PLPSITWFKDGWPVSLSNSVRILSGGRML 2442
Query: 380 ATFPTRQPGLGSQD-VVSKAANRRIPMEGQRDSAFPKF--ESKPQSQEVKENQTVKFRCE 436
T G VV AA + G P E+ + +VKE Q+V CE
Sbjct: 2443 RLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCE 2502
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
V+G P PE+ W +G P++ E + +G +L + + +G Y+C AS+ G
Sbjct: 2503 VTGNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHK 2559
Query: 497 SCSWTLQVERLAVMEVAPSFSSV-----LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551
S S++L V V+P+ + V +D VI L C P ITW +G
Sbjct: 2560 SRSFSLNV------FVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDG 2613
Query: 552 QPIQYARS-TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
P++ R+ G L I +A ++ G Y+C+A N G++ V V+ K +
Sbjct: 2614 TPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGD 2673
Query: 611 YLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH 670
P K ++K+ + +T+ + P + W +G ++ + +
Sbjct: 2674 LWGPGLSPK-----------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVN 2722
Query: 671 FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS----- 725
G H+L I+E DTG YTC A N AGE + +Q P + W I
Sbjct: 2723 IAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDT 2780
Query: 726 --KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKK 783
+ + + + C P PT+ W +DG L T +VL L + +
Sbjct: 2781 GRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPL---TSSDKVLILPGGRVLQIPR 2837
Query: 784 VQPWHAGQYEILLKNRVGECSCQ 806
+ AG+Y + N GE S Q
Sbjct: 2838 AKVEDAGRYTCVAVNEAGEDSLQ 2860
Score = 152 bits (383), Expect = 4e-36
Identities = 185/775 (23%), Positives = 275/775 (35%), Gaps = 135/775 (17%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR-NGQPITSGGRFLLDCGIRGTFSL 91
P FI P ++ ++ G+ V+GYPEP + W R + PI S + T +L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVET 151
I + D+G Y CEA N G Q +TV G AP +
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTG------------------LVAPLIGI 894
Query: 152 RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI-TGRPQPQVTWLKGNVPLQPSARVSVS 210
PS+ V EGQ C + G P P+ W+K + L + ++V
Sbjct: 895 SPSVAN--------------VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR 940
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSD 270
L I V D G YTC+ N +G + + + + L +
Sbjct: 941 SDGS---LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHG----------- 986
Query: 271 VRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPR 330
+ L ++E + C A+ P+P
Sbjct: 987 -----------QQILSTIEGIPVTLPCK-----------ASGNPKP-------------- 1010
Query: 331 TAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLG 390
+ + K I+ +A+ L V+SP GEE T G
Sbjct: 1011 ----SVIWSKKGELISTSSAKFSAGADG-SLYVVSPGGEESGEYV-----CTATNTAGYA 1060
Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
+ V R QR + + KP V + V CEV +P P + W E
Sbjct: 1061 KRKVQLTVYVRPRVFGDQRGLS----QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE 1116
Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510
T + + +GS + + + RT DSG Y C A+N G ++ + L V
Sbjct: 1117 -TQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVH----- 1168
Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELH 569
V P K V GQ + C+ +GTP+P ITW G + L
Sbjct: 1169 -VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS 1227
Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 629
I A P D G YTC+A N G + V E + E P F + +
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLE--------PPYNTTFQERV 1279
Query: 630 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE-DFHFEQRGTQHSLCIQEVFPE 688
++ ++ G P P + WLHNG E+ E + GT L I V P
Sbjct: 1280 AN------QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGT--LLVIASVTPY 1331
Query: 689 DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR--SVTASLGQSVLISCAIAG 746
D G Y C A N AG + L V P P K + +V+ L Q + C + G
Sbjct: 1332 DNGEYICVAVNEAGTTERKYNLKVHVP-----PVIKDKEQVTNVSVLLNQLTNLFCEVEG 1386
Query: 747 DPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
P P + W +D + ++ + + N + L L + P AG+Y N G
Sbjct: 1387 TPSPIIMWYKDNVQV-TESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIAG 1438
Score = 149 bits (376), Expect = 2e-35
Identities = 189/804 (23%), Positives = 285/804 (35%), Gaps = 137/804 (17%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
PR++ + E + P P +TW RNG+ + + R + G R L I+
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR---YLQINNADL 3684
Query: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
D YTC A+N +G LTV P+I G
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILTVN--------------------------VPPNIKGG 3718
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS-ARVSVSEKNGMQV 217
P L + V E C G P P++TW K L + AR S+ E NG
Sbjct: 3719 -PQSLVILLNKSTVLE-------CIAEGVPTPRITWRKDGAVLAGNHARYSILE-NGF-- 3767
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ-------------------------- 251
L I + D G Y C+ N +G +L +
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEA 3827
Query: 252 -GLDSANRSFVRETKATNSDVRKEVTNVISKESKL---DSLEAAAKSKNCSSPQRGGSPP 307
G+ + ++ + N D + ++S S + S++ A + C+ G
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA-TYECTVTNGAGDDK 3886
Query: 308 WAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAAR-----VQPEPRAPGLG 362
+ Q P S + D T V+ T+S + + ++ PR G
Sbjct: 3887 RTVDLTVQVP-PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR 3945
Query: 363 VLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK----AANRRIPMEGQRDSAFPKFES 418
+LS E T+ G V++ +A+R + + P +
Sbjct: 3946 ILSSGAIE----------ILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP---PVIQP 3992
Query: 419 KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
+P V N + CE +G P P + W EG V + V G L + +A
Sbjct: 3993 QPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAV 4049
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
D+GTY C A N G L V+ V P S LK+ + + L C
Sbjct: 4050 REDAGTYMCVAQNPAGTALGKIKLNVQ------VPPVISPHLKEYVIAVDKPITLSCEAD 4103
Query: 539 GTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWV 598
G P P ITW +G+ I + L I P D G YTC+A N G S S +
Sbjct: 4104 GLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Query: 599 TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
TVH R +E V + SQ + G P P + W
Sbjct: 4164 TVHVPPRIRSTE-------------------GHYTVNENSQAILPCVADGIPTPAINWKK 4204
Query: 659 NGNEIQE-SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
+ + + E G L ++ V ED+G YTC A N+AGE LTV
Sbjct: 4205 DNVLLANLLGKYTAEPYG---ELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVH---- 4257
Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
P F P V+ + G+ + +SC G P P + W + + HF+ +
Sbjct: 4258 -VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII---PAHFDSVNGHS-- 4311
Query: 778 TLVLKKVQPWHAGQYEILLKNRVG 801
LV+++V +G Y +N VG
Sbjct: 4312 ELVIERVSKEDSGTYVCTAENSVG 4335
Score = 149 bits (375), Expect = 3e-35
Identities = 119/423 (28%), Positives = 179/423 (42%), Gaps = 42/423 (9%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P+ S V EN C GIP P + W + + G E G L
Sbjct: 4169 PRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTA-EPYGE--LI 4225
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
L DSG Y+C A+NA G+ + + +L V V P+F+ + D ++ +G+ L
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVH------VLPTFTELPGDVSLNKGEQLRL 4279
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
C G P+P++TW N I A G +EL I+ ED GTY C AEN++G V
Sbjct: 4280 SCKATGIPLPKLTWTFNNNIIP-AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVK 4338
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
+V V E K +Y PS P+ G + +V G+P P
Sbjct: 4339 AIGFVYVKEPPVF-KGDY-----PSNWIEPL------------GGNAILNCEVKGDPTPT 4380
Query: 654 VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
+ W G +I+ S H ++ SL I ED G YTC A N AG V LT+Q
Sbjct: 4381 IQWNRKGVDIEIS---HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437
Query: 714 EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN 773
P P +P + G ++++C G+P PT+ W R G ++ D VL N
Sbjct: 4438 SP-----PIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWD-DRVNVLSN 4491
Query: 774 EDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCG 833
+L + Q ++E + +N +G +V +++Q + +C CG
Sbjct: 4492 N---SLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQVHG--GFSQWSAWRACSVTCG 4546
Query: 834 GGV 836
G+
Sbjct: 4547 KGI 4549
Score = 144 bits (364), Expect = 6e-34
Identities = 110/403 (27%), Positives = 171/403 (42%), Gaps = 41/403 (10%)
Query: 414 PKFESKPQSQEVK--ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH- 470
P ++ ++E+ + + C G P P +AW +G P+ ++ + +H
Sbjct: 3434 PNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPL-----GLDAHLTVSTHG 3488
Query: 471 -YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQ 529
L LLKA T DSG Y+C ASN G++S + L+V + + S ++ +VI
Sbjct: 3489 MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKV----LEPPHINGSEEHEEISVIVNN 3544
Query: 530 DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-LHIQDALPEDHGTYTCLAENA 588
L C G P P++TW+ +G+P+ G E L I A ED G YTCLA +
Sbjct: 3545 PLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSP 3604
Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
G V VH +P + P D+ V+ QVT+ +
Sbjct: 3605 AGDDDKEYLVRVH-----------VPPNIAGTDEP------RDITVLRNRQVTLECKSDA 3647
Query: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 708
PPP + WL NG +Q + G L I DT YTC A N AG+ +
Sbjct: 3648 VPPPVITWLRNGERLQATPRVRILSGG--RYLQINNADLGDTANYTCVASNIAGKTTREF 3705
Query: 709 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF 768
+LTV P P P+S+ L +S ++ C G P P + W +DG L + +
Sbjct: 3706 ILTVNVP-----PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARY 3760
Query: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
+L+N L ++ G+Y + N G ++ L +
Sbjct: 3761 SILENG---FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 139 bits (351), Expect = 2e-32
Identities = 106/390 (27%), Positives = 171/390 (43%), Gaps = 43/390 (11%)
Query: 420 PQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKART 479
P V N+ V C+V G P P++ WF +G P+ + ++E+ + L L AR
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--QVLHLKNARR 1517
Query: 480 RDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS--SVLKDCAVIEGQDFVLQCSV 537
D G Y CT SNA G+ + L + + PS +V D +V+ L+C
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIY------IPPSIKGGNVTTDISVLINSLIKLECET 1571
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAE-LHIQDALPEDHGTYTCLAENALGQVSCSA 596
RG P+P ITW +GQPI + + LHI A D TYTC N G
Sbjct: 1572 RGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA---- 1627
Query: 597 WVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
+KS Y+ P+ P+ + +V+ +T+ + +GNP P + W
Sbjct: 1628 ------EKSFHVDVYVPPMIEGNLATPL------NKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 657 LHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
L +G ++ +++ E G + + QE+ D G Y C A + AGE + + V P
Sbjct: 1676 LKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVLVP 1732
Query: 716 ---HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
G + + + + + C + G P PT+ WL+DG+ + + G F++L
Sbjct: 1733 PAIEGGDETSYF------IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDG-FKILL 1785
Query: 773 NEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
N LV+ + Q + G Y + N G+
Sbjct: 1786 NGR--KLVIAQAQVSNTGLYRCMAANTAGD 1813
Score = 137 bits (345), Expect = 1e-31
Identities = 105/389 (26%), Positives = 162/389 (41%), Gaps = 31/389 (7%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P V N V+ CE GIP P + W +G+PV ++V +G L
Sbjct: 2012 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILA 2069
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
L A+ D+G Y+C A NA G+ L+V V P+ ++ +V+ Q L
Sbjct: 2070 LTSAQISDTGRYTCVAVNAAGEKQRDIDLRV------YVPPNIMGEEQNVSVLISQAVEL 2123
Query: 534 QCSVRGTPVPRITWLLNGQP-IQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
C P P +TWL +G P ++ + + L I+DA +D G YTC A N G+
Sbjct: 2124 LCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKT 2183
Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
+ V + + S+ L+ L V++G+ +++ + SG PPP
Sbjct: 2184 EKNYNVNIWVPPNIGGSD-----------------ELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+IW G+ + L I D Y+C A N AG + + L V
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Query: 713 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
T S P + + G+S+ + C + G P PTV W++DG L K G E+L
Sbjct: 2287 YIRPTITNSG--SHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG-VEILD 2343
Query: 773 NEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
+ L LK + G+Y + N G
Sbjct: 2344 EGHI--LQLKNIHVSDTGRYVCVAVNVAG 2370
Score = 136 bits (342), Expect = 2e-31
Identities = 110/392 (28%), Positives = 165/392 (42%), Gaps = 42/392 (10%)
Query: 419 KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
K ++ V N + CEVSG P P+++W P++ ++ V G L +++A+
Sbjct: 2970 KSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIV---PGGRTLQIIRAK 3026
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF----SSVLKDCAVIEGQDFVLQ 534
D G Y+C A N G+ ++L V V PS S L V EG L+
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSLTVY------VPPSIKDHDSESLSVVNVREGTSVSLE 3080
Query: 535 CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCLAENALGQ 591
C P P ITW NG+ I ST +A+ LHI+ A D G Y C A N G+
Sbjct: 3081 CESNAVPPPVITWYKNGRMI--TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGR 3138
Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
+ + V+ +P + P + ++ +S+ VT+T +G PP
Sbjct: 3139 DDKNFHLNVY-----------VPPSIEGPEREVIVETISN-------PVTLTCDATGIPP 3180
Query: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLT 711
P + WL N I+ S+ L I D+G YTC A N G+ + L+
Sbjct: 3181 PTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 3240
Query: 712 VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK-DTGHFEV 770
+Q P P V+ LG++V + C G P P + WL+DGK + +T V
Sbjct: 3241 IQVPPSVAG---AEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRV 3297
Query: 771 LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
N TL + G+Y + N GE
Sbjct: 3298 SANGS--TLNIYGALTSDTGKYTCVATNPAGE 3327
Score = 135 bits (341), Expect = 3e-31
Identities = 154/637 (24%), Positives = 236/637 (37%), Gaps = 78/637 (12%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQV 217
PP V V G+ +C I +TW + + V L AR+
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--- 575
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA-----NRSFVRETK------A 266
LE+ V +D G Y C+V + G ++ S L++Q N+SF ++ A
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSA 635
Query: 267 TNSDVRKEVTNV-----ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321
T K V + + + KN + G A+NS + S
Sbjct: 636 TGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695
Query: 322 LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPAT 381
L ++P+ L IT+ + G+ P + K RP+T
Sbjct: 696 LRYI-EAPKLMVVQSELLVALGDITVMECKTS--------GIPPPQVKWFKGDLELRPST 746
Query: 382 FPTRQPGLG------SQD--------VVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKE 427
F P LG +QD V A R + P F +P ++
Sbjct: 747 FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEI 806
Query: 428 NQTVKFRCEVSGIPKPEVAWF-LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYS 486
V C V G P+P + W L+ P+ + S+ + L +L D GTY
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 487 CTASNAQGQLSCSWTLQVERLA--VMEVAPSFSSVLKDCAVIEGQDFVLQCSV-RGTPVP 543
C A N G++ T+ V L ++ ++PS ++V IEGQ L C++ G P+P
Sbjct: 867 CEAENQFGKIQSETTVTVTGLVAPLIGISPSVANV------IEGQQLTLPCTLLAGNPIP 920
Query: 544 RITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
W+ N + LHI+ +D G YTC+A N G + + V VH
Sbjct: 921 ERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-- 978
Query: 604 KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI 663
P G L ++G VT+ + SGNP P VIW G I
Sbjct: 979 -----------------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI 1021
Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ-EPHDGTQPW 722
S G SL + E++G Y C A N+AG + + LTV P
Sbjct: 1022 STSSAKF--SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQR 1079
Query: 723 FIS--KPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
+S KP ++ G+ V + C + P P + W ++
Sbjct: 1080 GLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE 1116
Score = 135 bits (341), Expect = 3e-31
Identities = 108/404 (26%), Positives = 173/404 (42%), Gaps = 38/404 (9%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
PK + P+ +V+ Q V C G P P + W G+ + +G V G+ L
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGEHHVSNPDGT--LS 1227
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-VAPSFSSVLKDCAVIEGQDFV 532
+ +A D+G Y+C A+N G TL V+ +E + P +++ ++ + Q
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQER--VANQRIE 1285
Query: 533 LQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
C +GTP P I WL NG+ + + S E G L I P D+G Y C+A N
Sbjct: 1286 FPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEA 1344
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G + VH + PV K + ++++ V+ + +V G
Sbjct: 1345 GTTERKYNLKVH----------VPPVIKDK-------EQVTNVSVLLNQLTNLFCEVEGT 1387
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
P P ++W + ++ ES G L + PED G Y+C+A N AG +
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYFN 1445
Query: 710 LTVQEPHDGTQPWFISK--PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
+ V P P I P V+ L + V + C + G PFP +HW +DGK L +
Sbjct: 1446 IDVLVP-----PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPN 1500
Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
E+L V L LK + G+Y+ + N G+ + + L +
Sbjct: 1501 VELLDRGQV--LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 125 bits (314), Expect = 4e-28
Identities = 101/388 (26%), Positives = 156/388 (40%), Gaps = 38/388 (9%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V N ++ C V+G P P + W +G + ++G + L + +A+ ++G
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGL 1802
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSF-SSVLKDCAVIEGQDFVLQCSVRGTPVP 543
Y C A+N G + + V V P+ SS L + V++ + LQC G P P
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVH------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNP 1856
Query: 544 RITWLLNGQPIQYARST--CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 601
ITWL + QP+ A+ ++ L I L ED G YTC+A NA G+ + VH
Sbjct: 1857 SITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 1916
Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
E S + +L + V+ + V + + +GNP P + W +
Sbjct: 1917 EPPSLEDAGKML-----------------NETVLVSNPVQLECKAAGNPVPVITWYKDNR 1959
Query: 662 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
+ S F RG + I+ D G Y C A NSAG L V P
Sbjct: 1960 LLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGATELFYSLQVH-----VAP 2012
Query: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
V + V + C G P P++ WL+DG + + +VL + L L
Sbjct: 2013 SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI--LAL 2070
Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSL 809
Q G+Y + N GE + L
Sbjct: 2071 TSAQISDTGRYTCVAVNAAGEKQRDIDL 2098
Score = 119 bits (298), Expect = 3e-26
Identities = 97/386 (25%), Positives = 155/386 (40%), Gaps = 34/386 (8%)
Query: 420 PQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKART 479
P V + V+ C +GIP P + W +G P+ E + A L + A T
Sbjct: 3253 PSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE-RIRVSANGSTLNIYGALT 3311
Query: 480 RDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 539
D+G Y+C A+N G+ + L V V + + ++C G
Sbjct: 3312 SDTGKYTCVATNPAGEEDRIFNLNVY---VTPTIRGNKDEAEKLMTLVDTSINIECRATG 3368
Query: 540 TPVPRITWLLNGQPIQYARSTCEAGVAE-LHIQDALPEDHGTYTCLAENALGQVSCSAWV 598
TP P+I WL NG P+ + + + I A D YTC+A N G
Sbjct: 3369 TPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG-------- 3420
Query: 599 TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
K L AP + G ++ V+ GS +M G P P + WL
Sbjct: 3421 ------VDNKHYNLQVFAPPNMDNSM---GTEEITVLKGSSTSMACITDGTPAPSMAWLR 3471
Query: 659 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH-- 716
+G + D H L + + ED+G YTC A N AGEV +L V EP
Sbjct: 3472 DGQPL--GLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHI 3529
Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
+G++ + ++ + + ++C +G P P + W++DG+ L T + L +V
Sbjct: 3530 NGSE-----EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL-PQTDQVQTLGGGEV 3583
Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGE 802
+ +V+ G+Y L + G+
Sbjct: 3584 LRISTAQVE--DTGRYTCLASSPAGD 3607
Score = 119 bits (297), Expect = 4e-26
Identities = 108/402 (26%), Positives = 156/402 (38%), Gaps = 48/402 (11%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P P + V N CE +GIPKP + W G + + Y S L
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQ-NSYRLLSSGSLV 3862
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
++ D+ TY CT +N G + L V +V PS + D V + V+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTV------QVPPSIADEPTDFLVTKHAPAVI 3916
Query: 534 QCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDH-GTYTCLAENAL 589
C+ G P P I W NG P +G E+ A +H G YTC+A NA
Sbjct: 3917 TCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEIL---ATQLNHAGRYTCVARNAA 3973
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G + VHE PV +P S+L V+ + + + + +G
Sbjct: 3974 GSAHRHVTLHVHEP----------PVIQPQP---------SELHVILNNPILLPCEATGT 4014
Query: 650 PPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 707
P P + W G + S H G Q S ++ ED GTY C A N AG +
Sbjct: 4015 PSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVR----EDAGTYMCVAQNPAGTALGK 4070
Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
L VQ P P + ++ + + +SC G P P + W +DG+A+ +
Sbjct: 4071 IKLNVQVP-----PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125
Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
VL + +L + VQP AG Y + N G S L
Sbjct: 4126 -RVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 118 bits (296), Expect = 5e-26
Identities = 102/407 (25%), Positives = 169/407 (41%), Gaps = 54/407 (13%)
Query: 420 PQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKART 479
P+ ++K N T+ CE IP ++W+ +G P++ + V A H L + +A+
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDD---HVNIAANGHTLQIKEAQI 2737
Query: 480 RDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI------EGQDFV- 532
D+G Y+C ASN G+ + + ++ V PSF + + ++ E +D +
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQ------VPPSFQKLWEIGNMLDTGRNGEAKDVII 2791
Query: 533 -----LQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPEDHGTYTCLAE 586
L C P P +TW +G P+ + + G L I A ED G YTC+A
Sbjct: 2792 NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAV 2851
Query: 587 NALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK----VMDGSQVTM 642
N G+ S V V L+P PI SDL V+ +
Sbjct: 2852 NEAGEDSLQYDVRV-----------LVP--------PIIKGANSDLPEEVTVLVNKSALI 2892
Query: 643 TVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
SG+P P W +G + E + F G + ++ D G Y C A N+AG
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI--TDIGRYVCVAENTAG 2950
Query: 703 EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
+ L V P P K ++T + + ++C ++G P P + WL++ + +
Sbjct: 2951 SAKKYFNLNVHVPPSVIGP----KSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIK 3006
Query: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
+T V TL + + + G+Y + N+ GE + SL
Sbjct: 3007 LNTNTLIVPGGR---TLQIIRAKVSDGGEYTCIAINQAGESKKKFSL 3050
Score = 115 bits (288), Expect = 4e-25
Identities = 99/390 (25%), Positives = 160/390 (41%), Gaps = 23/390 (5%)
Query: 417 ESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK 476
+ P+ V N CE P + WF +GTP+ E + + G L +L
Sbjct: 2579 DGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPL---ESNRNIRILPGGRTLQILN 2635
Query: 477 ARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVL--KDCAVIEGQDFVLQ 534
A+ ++G YSC A+N G++ + ++V ++ + L K+ + L+
Sbjct: 2636 AQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLE 2695
Query: 535 CSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
C P ++W +GQP++ A L I++A D G YTC+A N G+
Sbjct: 2696 CEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDE 2755
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
V + S +K L + T + V+ + +++ + + PPP
Sbjct: 2756 LDFDVNIQVPPSFQK---LWEIGNMLDTG----RNGEAKDVIINNPISLYCETNAAPPPT 2808
Query: 654 VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
+ W +G+ + S+ G L I ED G YTC A N AGE Q + V
Sbjct: 2809 LTWYKDGHPLTSSDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2866
Query: 714 EPH--DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771
P G P VT + +S LI C +G P P W +DG+ L +D H + L
Sbjct: 2867 VPPIIKGANS---DLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLED-DHHKFL 2922
Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
N + L + Q G+Y + +N G
Sbjct: 2923 SNGRI--LQILNTQITDIGRYVCVAENTAG 2950
Score = 114 bits (285), Expect = 9e-25
Identities = 100/394 (25%), Positives = 163/394 (41%), Gaps = 44/394 (11%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
PK P++Q V C +G PKP++AW + + GS Y L
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFI---VGS-HRYRMTSDGTLF 667
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
+ A +D+G Y C ASN+ G + TL+ AP V + V G V+
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------APKLMVVQSELLVALGDITVM 721
Query: 534 QCSVRGTPVPRITWL---LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG 590
+C G P P++ W L +P + G+ L IQ+ D G YTC+A N G
Sbjct: 722 ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL--LKIQETQDLDAGDYTCVAINEAG 779
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
+ + + V + P+F+Q +D+ + GS VT+ V G P
Sbjct: 780 RATGKITLDV-------------------GSPPVFIQEPADVSMEIGSNVTLPCYVQGYP 820
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQH--SLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 708
P + W N S F +L I ++ D GTY CEA N G+++++
Sbjct: 821 EPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSET 880
Query: 709 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA-IAGDPFPTVHWLRDGKALCKDTGH 767
+TV P P GQ + + C +AG+P P W+++ L ++
Sbjct: 881 TVTVT---GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-- 935
Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
+ ++++ +L +++VQ G+Y + N G
Sbjct: 936 YITVRSDG--SLHIERVQLQDGGEYTCVASNVAG 967
Score = 112 bits (280), Expect = 3e-24
Identities = 89/351 (25%), Positives = 147/351 (41%), Gaps = 39/351 (11%)
Query: 419 KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
K ++ V + V+ C+ +G P P + W+ + R GS + + + A+
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDN---RLLSGSTSMTFLNRGQIIDIESAQ 1982
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
D+G Y C A N+ G ++LQV VAPS S AV+ L+C R
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQVH------VAPSISGSNNMVAVVVNNPVRLECEAR 2036
Query: 539 GTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
G P P +TWL +G P+ + + +G L + A D G YTC+A NA G
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG------ 2090
Query: 597 WVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
EK+ +P P + ++ V+ V + Q PPP + W
Sbjct: 2091 -----EKQRDIDLRVYVP--------PNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTW 2137
Query: 657 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716
L +G+ + + + + L I++ +DTG YTCEA N AG+ + + P
Sbjct: 2138 LKDGHPLLKKPGLSISE--NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Query: 717 D--GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
+ G+ + +T G + + C +G P P + W + G + D+
Sbjct: 2196 NIGGS-----DELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDS 2241
Score = 107 bits (267), Expect = 1e-22
Identities = 81/337 (24%), Positives = 134/337 (39%), Gaps = 35/337 (10%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P F P + + + ++ C+ +GIP P++ W + S+ G L
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVN-----GHSELV 4314
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
+ + DSGTY CTA N+ G + + V+ V + + G + +L
Sbjct: 4315 IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFK-----GDYPSNWIEPLGGNAIL 4369
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
C V+G P P I W G I+ + + G L I + ED G YTC+A N G V
Sbjct: 4370 NCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4429
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
S +T+ P+ +P + + G ++ + Q +G P P
Sbjct: 4430 RSMSLTLQSP----------PIITLEPVETV---------INAGGKIILNCQATGEPQPT 4470
Query: 654 VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
+ W G+ I + + + +SL I + EDT + C A N G V + + VQ
Sbjct: 4471 ITWSRQGHSISWDDRVNVL---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Query: 714 EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFP 750
H G W S R+ + + G+ + + P P
Sbjct: 4528 -VHGGFSQW--SAWRACSVTCGKGIQKRSRLCNQPLP 4561
Score = 104 bits (260), Expect = 7e-22
Identities = 100/384 (26%), Positives = 159/384 (41%), Gaps = 49/384 (12%)
Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
C+ SGIP P+V WF +R S + D L + + + D+G Y+C A N G
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRP---STFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAG 779
Query: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWL-LNGQP 553
+ + TL V V P+ D ++ G + L C V+G P P I W L+ P
Sbjct: 780 RATGKITLDVGSPPVFIQEPA------DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMP 833
Query: 554 IQYARSTCEAGVAELH-----IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 608
I ++R + +++L I + D GTY C AEN G++ VTV
Sbjct: 834 I-FSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV-------- 884
Query: 609 SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQV-SGNPPPEVIWLHNGNEIQESE 667
+ AP+ S V++G Q+T+ + +GNP PE W+ N + ++
Sbjct: 885 ---------TGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 935
Query: 668 DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP 727
G+ H I+ V +D G YTC A N AG + V P
Sbjct: 936 YITVRSDGSLH---IERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-----VLPTIQHGQ 987
Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 787
+ ++ G V + C +G+P P+V W + G+ + + F + ++ V P
Sbjct: 988 QILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYV-----VSPG 1042
Query: 788 --HAGQYEILLKNRVGECSCQVSL 809
+G+Y N G +V L
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQL 1066
Score = 82.8 bits (203), Expect = 3e-15
Identities = 82/353 (23%), Positives = 138/353 (39%), Gaps = 38/353 (10%)
Query: 459 GSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSS 518
G + +++ S L + K D G Y C A ++ G T + + + P
Sbjct: 471 GVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAG------TGRAQTFFDVSEPPPVIQ 524
Query: 519 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA--ELHIQDALPE 576
V + V G+ VL C + +TW N + ++ A +A L ++
Sbjct: 525 VPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFN 584
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
D G Y C+ + G + S ++TV E P K T Q +
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTVQE--------------PPKVTVMPKNQSFT-----G 625
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
GS+V++ +G P P++ W N I S + GT L I+ P+D G Y C
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCL 682
Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
A NSAG + + L E P + + +LG ++ C +G P P V W +
Sbjct: 683 ASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK 737
Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
L T ++ + + L +++ Q AG Y + N G + +++L
Sbjct: 738 GDLELRPST---FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITL 787
Score = 74.7 bits (182), Expect = 8e-13
Identities = 67/274 (24%), Positives = 120/274 (43%), Gaps = 44/274 (16%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
L P+ + IK T E P ++W+++GQP+ S ++ G +L I
Sbjct: 2679 LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANG-HTLQIKEA 2735
Query: 97 HEEDRGKYTCEATNGSGARQVT--VELTVEGSFAK--QLGQPVVSKTLGDRFSAPAVETR 152
D G+YTC A+N +G ++ V + V SF K ++G + + G+
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE---------- 2785
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212
+ V+ + + C+ P P +TW K PL S +V +
Sbjct: 2786 ---------------AKDVIINNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILP- 2828
Query: 213 NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVR 272
G +VL+I +D G YTC+ VN +G+ S+ ++ + K NSD+
Sbjct: 2829 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV--------LVPPIIKGANSDLP 2879
Query: 273 KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP 306
+EVT +++K + ++ L + + + +S Q+ G P
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPR-NSWQKDGQP 2912
Score = 72.4 bits (176), Expect = 4e-12
Identities = 58/218 (26%), Positives = 86/218 (39%), Gaps = 38/218 (17%)
Query: 58 GYPEPQVTWHRNGQPI-TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQ 116
G P P +TW ++ QP+ T+ G + R L I ED G+YTC ATN +G Q
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGR---VLQIAKTLLEDAGRYTCVATNAAGETQ 1908
Query: 117 VTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQ 176
++L V P++E A K+ V
Sbjct: 1909 QHIQLHVH--------------------EPPSLED------------AGKMLNETVLVSN 1936
Query: 177 MGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVV 236
+ CK G P P +TW K N L S S++ N Q+++I D G+Y C+ +
Sbjct: 1937 PVQLECKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQIIDIESAQISDAGIYKCVAI 1994
Query: 237 NGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
N +G + L + S + S N+ VR E
Sbjct: 1995 NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLE 2032
Score = 72.4 bits (176), Expect = 4e-12
Identities = 63/242 (26%), Positives = 95/242 (39%), Gaps = 49/242 (20%)
Query: 1102 QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKAL 1161
+ L V+V EG + L+C+ ++ PP I W NG+ + + + + +G + + I+KA
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAE 3121
Query: 1162 PEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT 1221
D G Y C A N AG+ DD N P P + G E +
Sbjct: 3122 VSDTGQYVCRAINVAGR---------DDKNFHLNVYVP-----------PSIEGPEREVI 3161
Query: 1222 VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQES 1281
V+ P V L TG P T W+K K+I+ S
Sbjct: 3162 VETISNP--------------------------VTLTCDATGIPPPTIAWLKNHKRIENS 3195
Query: 1282 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS 1341
+ ++V GSKL I ++ G YT + N G Q L+ + P AG S
Sbjct: 3196 DSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS-IQVPPSVAGAEIPS 3254
Query: 1342 DI 1343
D+
Sbjct: 3255 DV 3256
Score = 72.0 bits (175), Expect = 5e-12
Identities = 57/212 (26%), Positives = 84/212 (39%), Gaps = 37/212 (17%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
P N+ + E + G P P +TW ++G P++ + G R L +
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR---MLRLMQTTM 2449
Query: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
ED G+YTC N +G + L+V P I GE
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVL--------------------------VPPHIVGE 2483
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
L V VKE Q +C++TG P P++TW K PLQ + +G + L
Sbjct: 2484 ------NTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII--SGGRFL 2535
Query: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+I V G YTCL + +G S S L++
Sbjct: 2536 QITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 71.6 bits (174), Expect = 7e-12
Identities = 58/213 (27%), Positives = 88/213 (41%), Gaps = 38/213 (17%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP-ITSGGRFLLDCGIRGTFSLVIHAVH 97
P + + G + E V+G P P VTW ++G P I + G +LD G L + +H
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG----HILQLKNIH 2354
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
D G+Y C A N +G +L+V AP PSI G
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVH---------------------AP-----PSIIG 2388
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+ V E +C+ +G P P +TW K P+ S V + +G ++
Sbjct: 2389 N-----HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--LSGGRM 2441
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
L + +D G YTC+V N +G+ LS+
Sbjct: 2442 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSV 2474
Score = 71.6 bits (174), Expect = 7e-12
Identities = 57/202 (28%), Positives = 81/202 (40%), Gaps = 34/202 (16%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
P ++ + G + G P P + W ++G+PI SG + G+ +L I+
Sbjct: 3253 PSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS-TLNIYGALT 3311
Query: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
D GKYTC ATN +G DR V P+I G
Sbjct: 3312 SDTGKYTCVATNPAGEE--------------------------DRIFNLNVYVTPTIRGN 3345
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
A KL +V C+ TG P PQ+ WLK +PL S+ + + QV+
Sbjct: 3346 --KDEAEKLMTLV---DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVI 3398
Query: 219 EIHGVNQDDVGVYTCLVVNGSG 240
I DV VYTC+ N +G
Sbjct: 3399 RIVRAQVSDVAVYTCVASNRAG 3420
Score = 70.9 bits (172), Expect = 1e-11
Identities = 53/200 (26%), Positives = 77/200 (38%), Gaps = 38/200 (19%)
Query: 51 KFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
+ E RG P P +TW ++G P++S L + G L + + D G+YTC A N
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 111 GSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
+G +Q ++L V PP + V
Sbjct: 2088 AAGEKQRDIDLRVY----------------------------------VPPNIMGEEQNV 2113
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
V Q C+ P P +TWLK PL +S+SE VL+I D G
Sbjct: 2114 SVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENR--SVLKIEDAQVQDTGR 2171
Query: 231 YTCLVVNGSGKASMSAELSI 250
YTC N +GK + ++I
Sbjct: 2172 YTCEATNVAGKTEKNYNVNI 2191
Score = 70.1 bits (170), Expect = 2e-11
Identities = 59/251 (23%), Positives = 98/251 (39%), Gaps = 46/251 (18%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+ + E P + P+N G+ GYP+P++ W N I R+ +
Sbjct: 606 LTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSD-- 663
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGA-RQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
GT L I +D G Y C A+N +G +Q + +E
Sbjct: 664 GT--LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEA-------------------- 701
Query: 146 APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
PK ++V G + CK +G P PQV W KG++ L+PS
Sbjct: 702 ---------------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Query: 206 RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
+ + G+ L+I D G YTC+ +N +G+A+ L + + F++E
Sbjct: 747 FLIIDPLLGL--LKIQETQDLDAGDYTCVAINEAGRATGKITLDV----GSPPVFIQEPA 800
Query: 266 ATNSDVRKEVT 276
+ ++ VT
Sbjct: 801 DVSMEIGSNVT 811
Score = 70.1 bits (170), Expect = 2e-11
Identities = 58/201 (28%), Positives = 86/201 (42%), Gaps = 38/201 (18%)
Query: 51 KFEGRVRGYPEPQVTWHRNGQPITSGGRFL-LDCGIRGTFSLVIHAVHEEDRGKYTCEAT 109
K E RG P P +TW+++GQPI S + L +D +G + L I D YTC
Sbjct: 1566 KLECETRGLPMPAITWYKDGQPIMSSSQALYID---KGQY-LHIPRAQVSDSATYTCHVA 1621
Query: 110 NGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGR 169
N +G T E SF + P P I G AT L +
Sbjct: 1622 NVAG--------TAEKSFHVDVYVP------------------PMIEGN----LATPLNK 1651
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
VV + CK G P P +TWLK VP++ + + + + G + LEI + D G
Sbjct: 1652 QVVIAHSL-TLECKAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRG 1708
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y C+ + +G+ + E+ +
Sbjct: 1709 QYICVATSVAGEKEIKYEVDV 1729
Score = 70.1 bits (170), Expect = 2e-11
Identities = 56/226 (24%), Positives = 89/226 (39%), Gaps = 41/226 (18%)
Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85
S+ + P F P ++ + +G + + G P P++TW N I + +
Sbjct: 4253 SLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SV 4307
Query: 86 RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G LVI V +ED G Y C A N G F K +G V +
Sbjct: 4308 NGHSELVIERVSKEDSGTYVCTAENSVG-------------FVKAIGFVYVKEP------ 4348
Query: 146 APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
P G+ P + LG + +C++ G P P + W + V ++ S
Sbjct: 4349 -------PVFKGDYPSNWIEPLGGNAI-------LNCEVKGDPTPTIQWNRKGVDIEISH 4394
Query: 206 RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
R+ + G L I+G +D G YTC+ N +G S L++Q
Sbjct: 4395 RI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437
Score = 64.7 bits (156), Expect = 8e-10
Identities = 50/213 (23%), Positives = 78/213 (36%), Gaps = 41/213 (19%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
P N G A V+G P P + W+R G I R G SL I+
Sbjct: 4356 PSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQ----LGNGSLAIYGTVN 4411
Query: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
ED G YTC ATN +G + ++ LT++
Sbjct: 4412 EDAGDYTCVATNEAGVVERSMSLTLQS--------------------------------- 4438
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
PP + V+ G +C+ TG PQP +TW + + RV+V N + +
Sbjct: 4439 -PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIA 4497
Query: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
+ ++D + C+ N G + + +Q
Sbjct: 4498 D---AQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 63.5 bits (153), Expect = 2e-09
Identities = 56/237 (23%), Positives = 89/237 (37%), Gaps = 40/237 (16%)
Query: 33 PAFILPPR--NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
P ++ P+ NL + V G+P P ++W +N QPI L+ + G +
Sbjct: 2963 PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRT 3019
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L I D G+YTC A N +G + LTV + P+++
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV--------------------YVPPSIK 3059
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
S L V V+EG C+ P P +TW K + S V +
Sbjct: 3060 DHDS----------ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL 3109
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI---QGLDSANRSFVRET 264
Q+L I D G Y C +N +G+ + L++ ++ R + ET
Sbjct: 3110 ADG--QMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVET 3164
Score = 63.2 bits (152), Expect = 2e-09
Identities = 73/322 (22%), Positives = 118/322 (36%), Gaps = 63/322 (19%)
Query: 1074 DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL 1133
+ C + T+N+ S P + Q + EG + L C+ S +P ++IW+
Sbjct: 957 EYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSK 1016
Query: 1134 NGKTLKTTKF-IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV----- 1187
G+ + T+ +GSL VS E+ G Y C A N AG A+ Q+TV
Sbjct: 1017 KGELISTSSAKFSAGADGSLYVVS---PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPR 1073
Query: 1188 ---------DDAPASENTKAPEMKSR--RPKSSLPPVLGTESDATVKKKPAPKTP--PKA 1234
D P + A E + KS PP++ + + +P+ P
Sbjct: 1074 VFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG 1133
Query: 1235 AM----------------------------------PPQIIQFPEDQKVRAGESVELFGK 1260
+M PP+I + P+ KV+ G+ V++
Sbjct: 1134 SMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCN 1193
Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
GT TW K + V N + L+I A G YT + N G+ +
Sbjct: 1194 AQGTPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 1321 AQVNLTVVDKP-----DPPAGT 1337
++ L V + P +PP T
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNT 1273
Score = 63.2 bits (152), Expect = 2e-09
Identities = 50/211 (23%), Positives = 82/211 (38%), Gaps = 38/211 (18%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEE 99
L + EG G P P + W + G P+ S GR + G R L I +
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGR---QLQISIAEKS 2262
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC 159
D Y+C A+N +G + L V + T+ + S P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQV-----------YIRPTITNSGSHPT----------- 2300
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
++V G+ C++ G P P VTW+K PL + V + ++ +L+
Sbjct: 2301 ---------EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG--HILQ 2349
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ ++ D G Y C+ VN +G +LS+
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 63.2 bits (152), Expect = 2e-09
Identities = 53/208 (25%), Positives = 74/208 (35%), Gaps = 36/208 (17%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
++EG + E P P +TW++NG+ IT + + L I D G+
Sbjct: 3071 VREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEI---LADGQMLHIKKAEVSDTGQ 3127
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C A N +G L V PSI G
Sbjct: 3128 YVCRAINVAGRDDKNFHLNVY--------------------------VPPSIEGPEREVI 3161
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
+ V +C TG P P + WLK + ++ S + V +G L+I
Sbjct: 3162 VETISNPVT-------LTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARS 3214
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQ 251
D G YTC+ N GKA LSIQ
Sbjct: 3215 QHSDSGNYTCIASNMEGKAQKYYFLSIQ 3242
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/216 (22%), Positives = 84/216 (38%), Gaps = 44/216 (20%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSG--GRFLLDCGIRGTFSLVIHA- 95
P + + E +V+G P P + W ++G+P+ G LLD G V+H
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG------QVLHLK 1513
Query: 96 -VHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154
D+G+Y C +N +G + ++LT+ + P+++
Sbjct: 1514 NARRNDKGRYQCTVSNAAGKQAKDIKLTI--------------------YIPPSIK---- 1549
Query: 155 IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214
G + + ++ + C+ G P P +TW K P+ S++ +K
Sbjct: 1550 -GGNVTTDISVLINSLI-------KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKG- 1600
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Q L I D YTC V N +G A S + +
Sbjct: 1601 -QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 60.1 bits (144), Expect = 2e-08
Identities = 62/258 (24%), Positives = 91/258 (35%), Gaps = 57/258 (22%)
Query: 7 VASSHISKT---------SLSVDPSRVDSMPLTEAPAFILP-PRNLCIKEGATAKFEGRV 56
+ S+H++ T + D R+D P I P P N+ +
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQ--VHVPPSIAPGPTNMTVIVNVQTTLACEA 3827
Query: 57 RGYPEPQVTWHRNGQPIT----SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
G P+P + W +NG + LL G SLVI + +D Y C TNG+
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSG-----SLVIISPSVDDTATYECTVTNGA 3882
Query: 113 GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVV 172
G + TV+LT V+ PSI E TK V+
Sbjct: 3883 GDDKRTVDLT--------------------------VQVPPSIADEPTDFLVTKHAPAVI 3916
Query: 173 KEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYT 232
+C +G P P + W K + L P +G +EI + G YT
Sbjct: 3917 --------TCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYT 3966
Query: 233 CLVVNGSGKASMSAELSI 250
C+ N +G A L +
Sbjct: 3967 CVARNAAGSAHRHVTLHV 3984
Score = 59.7 bits (143), Expect = 3e-08
Identities = 67/296 (22%), Positives = 107/296 (36%), Gaps = 38/296 (12%)
Query: 515 SFSSVLKDCAVIEGQD----FVLQ-----CSVRGTPVPRITWLLNGQPIQYARSTCEAGV 565
SFSS++ D + + + LQ CSV ++++ NG + + E+
Sbjct: 422 SFSSIVPDAPKVTMPEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESAS 481
Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIF 625
L I D G Y C+A ++ G + V E P
Sbjct: 482 VNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEP-------------------PPV 522
Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEV 685
+Q +++ V G + +T + + W N +++ +E SL ++ V
Sbjct: 523 IQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANL-SLELKSV 581
Query: 686 FPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIA 745
D G Y C + G LTVQEP P P++ + + G V I C+
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFLTVQEP-----PKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 746 GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
G P P + W + + G D TL +K P AG Y L N G
Sbjct: 637 GYPKPKIAWTVNDMFI---VGSHRYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAG 688
Score = 59.7 bits (143), Expect = 3e-08
Identities = 47/193 (24%), Positives = 80/193 (41%), Gaps = 31/193 (16%)
Query: 59 YPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
YP +TW ++G P+ S + + G +L I E++ G+Y+C ATN +G
Sbjct: 2602 YPPATITWFKDGTPLESNRNIRI---LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2658
Query: 119 VELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMG 178
E+ V P + + +WG P + K V +K
Sbjct: 2659 YEVKVY---------------------IPPIINKGDLWG---PGLSPK--EVKIKVNNTL 2692
Query: 179 RFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
C+ P ++W K PL+ V+++ NG L+I D G YTC+ N
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAA-NG-HTLQIKEAQISDTGRYTCVASNI 2750
Query: 239 SGKASMSAELSIQ 251
+G+ + +++IQ
Sbjct: 2751 AGEDELDFDVNIQ 2763
Score = 59.3 bits (142), Expect = 3e-08
Identities = 52/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%)
Query: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDA 1176
L C + PP TI W N K ++ + + + + I ++ D G Y C+A N
Sbjct: 3171 LTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNME 3230
Query: 1177 GQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAM 1236
G+A+ +++ P+ V G E
Sbjct: 3231 GKAQKYYFLSIQVPPS--------------------VAGAE------------------- 3251
Query: 1237 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
P D V GE+VEL G W+K K I E ++ S NGS L
Sbjct: 3252 ------IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLN 3305
Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
I A G YT + N G NL V P
Sbjct: 3306 IYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 58.9 bits (141), Expect = 4e-08
Identities = 65/241 (26%), Positives = 91/241 (37%), Gaps = 65/241 (26%)
Query: 7 VASSHISKTSLSVD-PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVT 65
VA S + T L+V P R+ S TE + + E + A G P P +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRS---TEG--------HYTVNENSQAILPCVADGIPTPAIN 4201
Query: 66 WHRNGQPITSGGRFLLDCGIRGTFS------LVIHAVHEEDRGKYTCEATNGSGARQVTV 119
W ++ +L + G ++ L++ V ED G YTC A N +G TV
Sbjct: 4202 WKKDN---------VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTV 4252
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
LTV P F G V + +G+ R
Sbjct: 4253 SLTV----------------------------------HVLPTFTELPGDVSLNKGEQLR 4278
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
SCK TG P P++TW N + P+ SV NG L I V+++D G Y C N
Sbjct: 4279 LSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVIERVSKEDSGTYVCTAENSV 4334
Query: 240 G 240
G
Sbjct: 4335 G 4335
Score = 58.5 bits (140), Expect = 6e-08
Identities = 57/222 (25%), Positives = 91/222 (40%), Gaps = 41/222 (18%)
Query: 56 VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
V G P P + W ++GQ I F + R LVI + G Y C A N +G
Sbjct: 1758 VTGSPPPTIMWLKDGQLIDERDGFKILLNGR---KLVIAQAQVSNTGLYRCMAANTAGDH 1814
Query: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
+ E+TV P+I K + RVVVK
Sbjct: 1815 KKEFEVTVH--------------------------VPPTI------KSSGLSERVVVKYK 1842
Query: 176 QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
+ C G P P +TWLK + P+ +A+ ++ ++ +VL+I +D G YTC+
Sbjct: 1843 PVA-LQCIANGIPNPSITWLKDDQPVN-TAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVA 1900
Query: 236 VNGSGKASMSAELSIQ---GLDSANRSFVRETKATNSDVRKE 274
N +G+ +L + L+ A + + ET ++ V+ E
Sbjct: 1901 TNAAGETQQHIQLHVHEPPSLEDAGK-MLNETVLVSNPVQLE 1941
Score = 58.2 bits (139), Expect = 8e-08
Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 49/218 (22%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
P N + + E + G P P +TW ++G P+ + ++ G + L I + E
Sbjct: 1648 PLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGK---KLEIMSAQE 1704
Query: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
DRG+Y C AT+ +G +++ E+ D PA+E
Sbjct: 1705 IDRGQYICVATSVAGEKEIKYEV--------------------DVLVPPAIEG------- 1737
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV- 217
+ +V + C +TG P P + WLK + E++G ++
Sbjct: 1738 -----GDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG--------QLIDERDGFKIL 1784
Query: 218 -----LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
L I + G+Y C+ N +G E+++
Sbjct: 1785 LNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV 1822
Score = 57.0 bits (136), Expect = 2e-07
Identities = 56/260 (21%), Positives = 88/260 (33%), Gaps = 53/260 (20%)
Query: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV 117
G P P + W +N + I + + + G L I D G YTC A+N G Q
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRI-LSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ- 3234
Query: 118 TVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG-ECPPKFATKLGRVVVKEGQ 176
++ +++ PS+ G E P + LG V
Sbjct: 3235 -------------------------KYYFLSIQVPPSVAGAEIPSDVSVLLGENV----- 3264
Query: 177 MGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVV 236
C G P P + WLK P+ + L I+G D G YTC+
Sbjct: 3265 --ELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVAT 3322
Query: 237 NGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKN 296
N +G+ L++ +V T N D +++ ++ S+ ++
Sbjct: 3323 NPAGEEDRIFNLNV---------YVTPTIRGNKDEAEKLMTLVD-----TSINIECRATG 3368
Query: 297 CSSPQRGGSPPWAANSQPQP 316
PQ W N P P
Sbjct: 3369 TPPPQIN----WLKNGLPLP 3384
Score = 56.6 bits (135), Expect = 2e-07
Identities = 56/244 (22%), Positives = 94/244 (38%), Gaps = 48/244 (19%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG--RFLLDCGIRGTFSLVIHAV 96
P + + +A E G P P+ +W ++GQP+ +FL + I L I
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRI-----LQILNT 2933
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIW 156
D G+Y C A N +G+ + L V PS+
Sbjct: 2934 QITDIGRYVCVAENTAGSAKKYFNLNVH--------------------------VPPSVI 2967
Query: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
G K + V +C+++G P P ++WLK P++ + + G +
Sbjct: 2968 GP-------KSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGR 3018
Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL------SIQGLDSANRSFVRETKATNSD 270
L+I D G YTC+ +N +G++ L SI+ DS + S V + T+
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3078
Query: 271 VRKE 274
+ E
Sbjct: 3079 LECE 3082
Score = 55.8 bits (133), Expect = 4e-07
Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 38/200 (19%)
Query: 51 KFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
+ E + G P P +TW+++ + + SG + RG + I + D G Y C A N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNR-LLSGSTSMTFLN-RGQI-IDIESAQISDAGIYKCVAIN 1995
Query: 111 GSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
+GA ++ F + V PSI G + + V
Sbjct: 1996 SAGATEL--------------------------FYSLQVHVAPSISG------SNNMVAV 2023
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
VV R C+ G P P +TWLK P+ S + +G ++L + D G
Sbjct: 2024 VVNNPV--RLECEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGR 2080
Query: 231 YTCLVVNGSGKASMSAELSI 250
YTC+ VN +G+ +L +
Sbjct: 2081 YTCVAVNAAGEKQRDIDLRV 2100
Score = 55.8 bits (133), Expect = 4e-07
Identities = 52/226 (23%), Positives = 85/226 (37%), Gaps = 48/226 (21%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
++ V GK + L+C+V PP T+ W +G L K + + EG + + ++ D
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSDT 2358
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
G Y CVA N AG + ++V AP P ++G
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSV-HAP-------------------PSIIGNH-------- 2390
Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
+ PE+ V SV L + +G + TW K + S ++
Sbjct: 2391 ----------------RSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVR 2434
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ G L ++ E G YT +V N G + L+V+ P
Sbjct: 2435 I--LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 55.5 bits (132), Expect = 5e-07
Identities = 60/275 (21%), Positives = 100/275 (36%), Gaps = 49/275 (17%)
Query: 1103 KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALP 1162
K+ + V + L+C+ + +P I W + + L + + G + + IE A
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQI 1983
Query: 1163 EDRGLYKCVAKNDAGQAECSCQVTVDDAPA---------------------SENTKAPE- 1200
D G+YKCVA N AG E + V AP+ + AP
Sbjct: 1984 SDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSL 2043
Query: 1201 --MKSRRPKSSLPPVLGTESDATVKKKPAPKTPP---------------------KAAMP 1237
+K P SS L S + + + + +P
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103
Query: 1238 PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1297
P I+ ++ V ++VEL + P T TW+K + + + + SEN S L I
Sbjct: 2104 PNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSI--SENRSVLKI 2161
Query: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
A+ + G YT N G + N+ + P+
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPN 2196
Score = 55.5 bits (132), Expect = 5e-07
Identities = 52/212 (24%), Positives = 82/212 (38%), Gaps = 49/212 (23%)
Query: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDA 1176
L C+ ++ PP T+ W +G L ++ +++ G + + I +A ED G Y CVA N+A
Sbjct: 2797 LYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEA 2854
Query: 1177 GQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL-GTESDATVKKKPAPKTPPKAA 1235
G+ V V +PP++ G SD
Sbjct: 2855 GEDSLQYDVRV---------------------LVPPIIKGANSD---------------- 2877
Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
PE+ V +S + +G+ +W K + + E +H K NG L
Sbjct: 2878 -------LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRIL 2928
Query: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
IL + G Y + EN GS + NL V
Sbjct: 2929 QILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Score = 55.1 bits (131), Expect = 6e-07
Identities = 53/213 (24%), Positives = 79/213 (37%), Gaps = 49/213 (23%)
Query: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
L L+C+ + +P + W +G +K I + G + I A DRG Y CVA +
Sbjct: 1659 LTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATS 1716
Query: 1175 DAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKA 1234
AG+ E +V V PA E G E+ +
Sbjct: 1717 VAGEKEIKYEVDVLVPPAIEG-------------------GDETSYFI------------ 1745
Query: 1235 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSK 1294
V +EL VTG+ P T W+K + I E + K+ NG K
Sbjct: 1746 --------------VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKI--LLNGRK 1789
Query: 1295 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
L I A+ + G Y + N G + + +TV
Sbjct: 1790 LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV 1822
Score = 54.7 bits (130), Expect = 8e-07
Identities = 48/196 (24%), Positives = 77/196 (39%), Gaps = 38/196 (19%)
Query: 56 VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
V G P P + W+++ +T + L + ED G+Y+C+A N +G
Sbjct: 1384 VEGTPSPIIMWYKDNVQVTESSTIQT---VNNGKILKLFRATPEDAGRYSCKAINIAGTS 1440
Query: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
Q + V L P + +G F P + + L R V E
Sbjct: 1441 QKYFNIDV-------LVPPTI---IGTNF---------------PNEVSVVLNRDVALE- 1474
Query: 176 QMGRFSCKITGRPQPQVTWLKGNVPL-QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
C++ G P P + W K PL V + ++ QVL + ++D G Y C
Sbjct: 1475 ------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--QVLHLKNARRNDKGRYQCT 1526
Query: 235 VVNGSGKASMSAELSI 250
V N +GK + +L+I
Sbjct: 1527 VSNAAGKQAKDIKLTI 1542
Score = 54.3 bits (129), Expect = 1e-06
Identities = 51/227 (22%), Positives = 88/227 (38%), Gaps = 39/227 (17%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
++V + L L+C+ + P A++ W +G+ LK+ + ++ G ++ I++A D
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISD 2739
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
G Y CVA N AG+ E V + P+ + + +L T +
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQVPPSFQKL-----------WEIGNMLDTGRNG---- 2784
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
E + V + L+ + P T TW K + S+
Sbjct: 2785 --------------------EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSD-- 2822
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
KV G L I A+ E G YT + N+ G Q ++ V+ P
Sbjct: 2823 KVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPP 2869
Score = 53.5 bits (127), Expect = 2e-06
Identities = 81/391 (20%), Positives = 145/391 (37%), Gaps = 68/391 (17%)
Query: 1029 AKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNE 1088
AK + + P P T P G+ K E S S L C + +
Sbjct: 1114 AKETQLISPFS---PRHTFLPSGSMKITETRTSDSGMYL---------CVATNIAGNVTQ 1161
Query: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILS 1147
+ P ++ + + V G+++ + C P I W+ G T+ + + +
Sbjct: 1162 AVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207
+G+L SI++A P D G+Y CVA N AG E + V + P E+ + P
Sbjct: 1222 PDGTL---SIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP-------- 1270
Query: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267
+ T +++ A Q I+FP K GT
Sbjct: 1271 ----------YNTTFQERVA----------NQRIEFPCPAK--------------GTPKP 1296
Query: 1268 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
T W+ +++ E + E+G+ L I + G Y + N+ G+ + + NL
Sbjct: 1297 TIKWLHNGRELTGRE-PGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNL-- 1353
Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST 1387
K P + + S+ L+ + + S I +W N E +T ++
Sbjct: 1354 --KVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPS-PIIMWYKDNVQVTESSTIQTV 1410
Query: 1388 S----FNVQDLLPDHEYKFRVRAINVYGTSE 1414
+ + P+ ++ +AIN+ GTS+
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTSQ 1441
Score = 53.5 bits (127), Expect = 2e-06
Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 41/201 (20%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV--HEE 99
+ + +G++ G P P + W R+GQP+ + T +V+ + E
Sbjct: 3445 ITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-----THGMVLQLLKAETE 3499
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC 159
D GKYTC A+N +G V F ++ +P P I G
Sbjct: 3500 DSGKYTCIASNEAG--------EVSKHFILKVLEP------------------PHING-- 3531
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
+ + + V +C +G P P++TW+K PL + +V G +VL
Sbjct: 3532 ----SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQT--LGGGEVLR 3585
Query: 220 IHGVNQDDVGVYTCLVVNGSG 240
I +D G YTCL + +G
Sbjct: 3586 ISTAQVEDTGRYTCLASSPAG 3606
Score = 52.4 bits (124), Expect = 4e-06
Identities = 58/250 (23%), Positives = 95/250 (38%), Gaps = 52/250 (20%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSLCSVSIEKALPE 1163
DV V G+ + L C + P I W +GK + + T+ I +S GS +++I AL
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTS 3312
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y CVA N AG+ + + V P + G + +A
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNV--------------------YVTPTIRGNKDEA--- 3349
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
E S+ + + TGT P W+K + S H
Sbjct: 3350 ---------------------EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSH 3388
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPAGTPCAS 1341
+++ + G + I+ A+ YT + N+ G NL V P D GT +
Sbjct: 3389 IRLLAA--GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446
Query: 1342 DIRSSSLTLS 1351
++ SS +++
Sbjct: 3447 VLKGSSTSMA 3456
Score = 51.6 bits (122), Expect = 7e-06
Identities = 50/227 (22%), Positives = 89/227 (39%), Gaps = 43/227 (18%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
+DV V L C+ S PPATI W +G L++ + I + G ++ I A ++
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGR--TLQILNAQEDN 2640
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
G Y CVA N+AG+ +K K +PP++ + D
Sbjct: 2641 AGRYSCVATNEAGEM---------------------IKHYEVKVYIPPII-NKGDLW--- 2675
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
P PK + K++ ++ L + + +W K + ++ +H+
Sbjct: 2676 --GPGLSPK------------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHV 2721
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ + NG L I A+ G YT + N G + ++ + P
Sbjct: 2722 NI--AANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Score = 51.6 bits (122), Expect = 7e-06
Identities = 55/232 (23%), Positives = 79/232 (34%), Gaps = 56/232 (24%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCSV 1155
P + + ++HV +LL C+ + P I W G + T+ +L G +
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG----L 4043
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1215
I +A+ ED G Y CVA+N AG A ++ V P +P +K P L
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI----SPHLKEYVIAVDKPITLS 4099
Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
E+D G P TW K
Sbjct: 4100 CEAD-------------------------------------------GLPPPDITWHKDG 4116
Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+ I ES +V +S L I + G YT + N GS LTV
Sbjct: 4117 RAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 51.6 bits (122), Expect = 7e-06
Identities = 62/279 (22%), Positives = 99/279 (35%), Gaps = 54/279 (19%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P L++ +A K + L C+ PP I W +G+ + + + GSL +
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFV 4138
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP------ 1211
+ P D G Y C+A N AG + S ++TV P +T+ + ++ LP
Sbjct: 4139 Q---PGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI 4195
Query: 1212 --PVLGTESD--------------------------------ATVKKKPAPKTPPKAAMP 1237
P + + D V A + ++
Sbjct: 4196 PTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT 4255
Query: 1238 ----PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG- 1292
P + P D + GE + L K TG TW F I + +S NG
Sbjct: 4256 VHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW-TFNNNIIPAHF----DSVNGH 4310
Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
S+L I +E G Y EN +G +A + V +P
Sbjct: 4311 SELVIERVSKEDSGTYVCTAENSVGFVKA-IGFVYVKEP 4348
Score = 50.8 bits (120), Expect = 1e-05
Identities = 63/278 (22%), Positives = 97/278 (34%), Gaps = 53/278 (19%)
Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1136
C ++ TD + + AP ++ VA G +++C+ S PP + W
Sbjct: 681 CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740
Query: 1137 TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT 1196
L+ + F+I+ + L + I++ D G Y CVA N+AG+A + ++T+D
Sbjct: 741 ELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGRA--TGKITLD-------- 788
Query: 1197 KAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1256
PP IQ P D + G +V
Sbjct: 789 -------------------------------------VGSPPVFIQEPADVSMEIGSNVT 811
Query: 1257 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE--NGSKLTILAARQEHCGCYTLLVEN 1314
L V G T W + S V + L IL G Y EN
Sbjct: 812 LPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAEN 871
Query: 1315 KLGSRQAQVNLTVVDKPDPPAG--TPCASDIRSSSLTL 1350
+ G Q++ +TV P G A+ I LTL
Sbjct: 872 QFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTL 909
Score = 49.7 bits (117), Expect = 3e-05
Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 9/135 (6%)
Query: 679 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 738
+L I +V D G Y C A +SAG R Q V EP P I P +VT + G+
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEP-----PPVIQVPNNVTVTPGERA 537
Query: 739 LISCAIAGDPFPTVHWLR-DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797
+++C I + W R D + L N +L LK V+ AG+Y ++
Sbjct: 538 VLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVS 594
Query: 798 NRVGECSCQVSLMLQ 812
+ G + V L +Q
Sbjct: 595 SEGGSSAASVFLTVQ 609
Score = 49.7 bits (117), Expect = 3e-05
Identities = 51/218 (23%), Positives = 78/218 (35%), Gaps = 51/218 (23%)
Query: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
L L C V+ PP TI+W +G+ + + G + I +A + GLY+C+A N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGR--KLVIAQAQVSNTGLYRCMAAN 1809
Query: 1175 DAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKA 1234
AG + +VTV P +++ G VK KP
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSS------------------GLSERVVVKYKPVALQCIAN 1851
Query: 1235 AMP-PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
+P P I +DQ V + ++K+++S G
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQG----------------------------NLKIQSS--GR 1881
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
L I E G YT + N G Q + L V + P
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 49.7 bits (117), Expect = 3e-05
Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
P +K + S+++ + V EG++ +C+ P P + W+K+ + I ES H +I D
Sbjct: 3056 PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ-- 3113
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
L I D +Y C+A+N G L V EG E
Sbjct: 3114 -MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPERE 3159
Score = 49.7 bits (117), Expect = 3e-05
Identities = 51/216 (23%), Positives = 80/216 (37%), Gaps = 53/216 (24%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G +L C+V DP TI W G ++ + I GSL +I + ED G Y CV
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYTCV 4420
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A N+AG E S +T+ PP++ E
Sbjct: 4421 ATNEAGVVERSMSLTLQS---------------------PPIITLE-------------- 4445
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
P + + AG + L + TG T TW + I + + V ++
Sbjct: 4446 ------------PVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN-- 4491
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+ L I A++E + + N +GS +V + V
Sbjct: 4492 -NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 49.3 bits (116), Expect = 4e-05
Identities = 46/215 (21%), Positives = 77/215 (35%), Gaps = 51/215 (23%)
Query: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDA 1176
+ C V S P T+ + NG TL +++ +E + ++ I K D G Y+C+A + A
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYL---KESASVNLDIAKVTLSDEGFYECIAVSSA 505
Query: 1177 GQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAM 1236
G V +
Sbjct: 506 GTGRAQTFFDVSE----------------------------------------------- 518
Query: 1237 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
PP +IQ P + V GE L + TW + + ++ +E ++ N S L
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LE 577
Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ + + G Y +V ++ GS A V LTV + P
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612
Score = 49.3 bits (116), Expect = 4e-05
Identities = 51/229 (22%), Positives = 82/229 (35%), Gaps = 53/229 (23%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
+++ V E + L C+ S P +I W +G + + + + G + + + + ED
Sbjct: 2394 ENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMED 2451
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
G Y CV +N AG+ ++V
Sbjct: 2452 AGQYTCVVRNAAGEERKIFGLSV------------------------------------- 2474
Query: 1225 KPAPKTPPKAAMPPQII--QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
+PP I+ ED KV+ +SV L +VTG TW K + +QE E
Sbjct: 2475 ----------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524
Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ G L I + H G YT L + G + +L V P
Sbjct: 2525 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSP 2571
Score = 47.8 bits (112), Expect = 1e-04
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
HV P F++ D+ + +G R CK G P P++ W ++ I HF +G+
Sbjct: 4257 HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII--PAHFD---SVNGHS 4311
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
L+I V +D Y C A NS+G
Sbjct: 4312 ELVIERVSKEDSGTYVCTAENSVG 4335
Score = 47.4 bits (111), Expect = 1e-04
Identities = 46/214 (21%), Positives = 78/214 (36%), Gaps = 46/214 (21%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L+DV V E + + L C+V+ +P I W +G+ L+ + + G + I
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVP 2543
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
G Y C+A + AG S + V +P + G SD
Sbjct: 2544 HTGRYTCLASSPAGHKSRSFSLNVFVSPT--------------------IAGVGSDGN-- 2581
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
PED V L + P T TW K ++ + +
Sbjct: 2582 --------------------PEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317
+++ G L IL A++++ G Y+ + N+ G
Sbjct: 2622 IRI--LPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 47.0 bits (110), Expect = 2e-04
Identities = 58/249 (23%), Positives = 93/249 (37%), Gaps = 53/249 (21%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
+++ V +G + C P ++ W +G+ L + +S G + + + KA ED
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMV--LQLLKAETED 3500
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
G Y C+A N+AG E +K +K P P + G+E
Sbjct: 3501 SGKYTCIASNEAG----------------EVSKHFILKVLEP----PHINGSEEH----- 3535
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
E+ V +EL +G TWMK + + +++
Sbjct: 3536 --------------------EEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD-- 3573
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI- 1343
+V+ G L I A+ E G YT L + G + L V P AGT DI
Sbjct: 3574 QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY-LVRVHVPPNIAGTDEPRDIT 3632
Query: 1344 --RSSSLTL 1350
R+ +TL
Sbjct: 3633 VLRNRQVTL 3641
Score = 46.6 bits (109), Expect = 2e-04
Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 3/94 (3%)
Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
HV P + L +EG CK G P P V+W K + I S + +
Sbjct: 978 HVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS---SAKFSAGADG 1034
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
SL + G++ +Y C A N+ G A +L V
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 46.6 bits (109), Expect = 2e-04
Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 3/97 (3%)
Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
HV P T V E S A C +G P P + W KD+ + + Y +
Sbjct: 4166 HVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL---ANLLGKYTAEPYG 4222
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
LI+ +V +D YTC A N+ GE T T L V +
Sbjct: 4223 ELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVL 4259
Score = 45.8 bits (107), Expect = 4e-04
Identities = 61/259 (23%), Positives = 88/259 (33%), Gaps = 55/259 (21%)
Query: 1082 AGTTDNEKRSESQGTAPAFKQKLQ--DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK 1139
AGTT+ K + P K K Q +V V + L C+V P I+W + +
Sbjct: 1344 AGTTER-KYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVT 1402
Query: 1140 TTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1199
+ I G + + + +A PED G Y C A N AG ++ + V
Sbjct: 1403 ESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV------------ 1448
Query: 1200 EMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQII--QFPEDQKVRAGESVEL 1257
+PP II FP + V V L
Sbjct: 1449 -----------------------------------LVPPTIIGTNFPNEVSVVLNRDVAL 1473
Query: 1258 FGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317
+V GT W K K + + VE + G L + AR+ G Y V N G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 1318 SRQAQVNLTVVDKPDPPAG 1336
+ + LT+ P G
Sbjct: 1533 KQAKDIKLTIYIPPSIKGG 1551
Score = 45.8 bits (107), Expect = 4e-04
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE-SRHFQIDYDEDGN 1813
HV P S + + VV + R +C+ G P P + W KD + S Q+ G
Sbjct: 2009 HVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQV---LSGG 2065
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGE 1839
L ++ D +YTC AVN+ GE
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGE 2091
Score = 45.8 bits (107), Expect = 4e-04
Identities = 39/142 (27%), Positives = 55/142 (38%), Gaps = 12/142 (8%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
GD VA++ S+ S+ L P L P I G + G P+
Sbjct: 4415 GDYTCVATNEAGVVERSM------SLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQ 4468
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTV 119
P +TW R G I+ R + SL I +ED ++ C A N GS +V V
Sbjct: 4469 PTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524
Query: 120 ELTVEGSFAKQLGQPVVSKTLG 141
+ V G F++ S T G
Sbjct: 4525 IVQVHGGFSQWSAWRACSVTCG 4546
Score = 45.4 bits (106), Expect = 5e-04
Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 5/118 (4%)
Query: 1082 AGTTDNEKRSESQGTA---PAFKQK-LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137
A T + + E + T P K L + V + K + LQC + P +I W + +
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195
+ T + + Q + I K L ED G Y CVA N AG+ + Q+ V + P+ E+
Sbjct: 1867 VNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLED 1923
Score = 45.4 bits (106), Expect = 5e-04
Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 5/98 (5%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
++ V++GS+ C +G P P + W +D Q + H + L + +D
Sbjct: 3444 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV---STHGMVLQLLKAETED 3500
Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
KYTC A N GE + I++ +E G EE E
Sbjct: 3501 SGKYTCIASNEAGEV--SKHFILKVLEPPHINGSEEHE 3536
Score = 45.1 bits (105), Expect = 7e-04
Identities = 36/155 (23%), Positives = 64/155 (41%), Gaps = 10/155 (6%)
Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
WQK G V GR ++ GL ++ + + + + + + L
Sbjct: 4021 WQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV----- 4075
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
V P S +++ + C+ +G P P++ W KD ++I ES ++ +
Sbjct: 4076 -QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV----LSS 4130
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
SL I+ V D YTC A N G ++ + +L V
Sbjct: 4131 GSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 44.7 bits (104), Expect = 9e-04
Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
+L V G +CK G P P+V WFK D +R S ID L I + D
Sbjct: 710 ELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID---PLLGLLKIQETQDLD 766
Query: 1826 DAKYTCKAVNSLGEAT 1841
YTC A+N G AT
Sbjct: 767 AGDYTCVAINEAGRAT 782
Score = 44.7 bits (104), Expect = 9e-04
Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Query: 1753 KPHVKPYFS--KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
K HV P + + ++ V+ C++EG P P ++W+KD+ + ES Q
Sbjct: 1354 KVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ---TV 1410
Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
+ L + +D +Y+CKA+N G
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAG 1438
Score = 44.7 bits (104), Expect = 9e-04
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
PH+ T+ D++V E + C++ G P PE+ W KD Q ++E I G
Sbjct: 2478 PHIVG--ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHI---ISGG 2532
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
L I++V +YTC A + G + + L V G G +
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSD 2579
Score = 43.9 bits (102), Expect = 0.001
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Query: 1755 HVKPYF-SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
HV P S + + VV+ C G P+P + W KDDQ + ++ + G
Sbjct: 1823 HVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGR 1881
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1859
L I+ +D +YTC A N+ GE +L V E G+
Sbjct: 1882 V-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGK 1926
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/98 (29%), Positives = 39/98 (39%), Gaps = 1/98 (1%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
D+ V+ G C G P P + W KD + I +I +G+ +L I D
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSD 3313
Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
KYTC A N GE L V G +E E+
Sbjct: 3314 TGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351
Score = 43.5 bits (101), Expect = 0.002
Identities = 45/226 (19%), Positives = 82/226 (36%), Gaps = 48/226 (21%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
D+ V + L+C+ P I W +G+ + ++ + +G + I +A D
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDS 1613
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
Y C N AG AE S V V P E A
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLAT-------------------------- 1647
Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
P +++V S+ L K G TW+K ++ +++++
Sbjct: 1648 ------------------PLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR 1689
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+E G KL I++A++ G Y + + G ++ + + V+ P
Sbjct: 1690 IE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPP 1733
Score = 43.5 bits (101), Expect = 0.002
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
+D+ V +++ L+C+ + PP I W NG+ L+ T + + G + I A D
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGD 3686
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAP 1191
Y CVA N AG+ +TV+ P
Sbjct: 3687 TANYTCVASNIAGKTTREFILTVNVPP 3713
Score = 43.1 bits (100), Expect = 0.003
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
D+ V+ S + +C+ G P P + W+KD Q I S Q Y + G L I D
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSD 1612
Query: 1826 DAKYTCKAVNSLG--EATCTAELIVETMEEG 1854
A YTC N G E + ++ V M EG
Sbjct: 1613 SATYTCHVANVAGTAEKSFHVDVYVPPMIEG 1643
Score = 43.1 bits (100), Expect = 0.003
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 1755 HVKP-YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
HV P +L VV + C++ G+P P++ W K++Q I+ + + I G
Sbjct: 2961 HVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGG 3017
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEA 1840
+L I D +YTC A+N GE+
Sbjct: 3018 RTLQIIRAKVSDGGEYTCIAINQAGES 3044
Score = 42.0 bits (97), Expect = 0.006
Identities = 37/153 (24%), Positives = 66/153 (43%), Gaps = 20/153 (13%)
Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESE-EDVSQAFLEAVAEE 1752
W+K G+ V SM + LSG G AEK ++ + + A++
Sbjct: 2230 WKKKGSPVLT----DSMGRVRILSG-----GRQLQISIAEKSDAALYSCVASNVAGTAKK 2280
Query: 1753 KPHVKPYFSKTIR-------DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
+ +++ Y TI ++ V G + +C+++G P P V W KD + +++ +
Sbjct: 2281 EYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVE 2340
Query: 1806 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
I D L + ++ D +Y C AVN G
Sbjct: 2341 I---LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-DYDEDGNCSL 1816
P F + D+ + GS C ++GYP+P + W + D SR F + + +L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 1817 IISDVCGDDDAKYTCKAVNSLGE 1839
I ++ D Y C+A N G+
Sbjct: 853 FILNLWASDKGTYICEAENQFGK 875
Score = 41.6 bits (96), Expect = 0.007
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 3/74 (4%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
D+ V+ S C+ YP + WFKD + +R+ +I G +L I + D+
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI---LPGGRTLQILNAQEDN 2640
Query: 1826 DAKYTCKAVNSLGE 1839
+Y+C A N GE
Sbjct: 2641 AGRYSCVATNEAGE 2654
Score = 40.8 bits (94), Expect = 0.012
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 3/74 (4%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
++ VVE ++ C+ G P P + WFKD + S +I G L + +D
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMED 2451
Query: 1826 DAKYTCKAVNSLGE 1839
+YTC N+ GE
Sbjct: 2452 AGQYTCVVRNAAGE 2465
Score = 40.8 bits (94), Expect = 0.012
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Query: 1755 HVKPYFSKTI--RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
HV P + T RD+ V+ +CK + P P + W ++ + ++ + +I G
Sbjct: 3617 HVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRI---LSG 3673
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEAT 1841
L I++ D A YTC A N G+ T
Sbjct: 3674 GRYLQINNADLGDTANYTCVASNIAGKTT 3702
Score = 40.8 bits (94), Expect = 0.012
Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 1/95 (1%)
Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
HV P + ++ V+ C+ G P P + W K+ + ++ Q Y +
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQN-QNSYRLLSSG 3859
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
SL+I DD A Y C N G+ T +L V+
Sbjct: 3860 SLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894
Score = 40.4 bits (93), Expect = 0.016
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 1108 HVAEGKKLLLQCQV-SSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+V EG++L L C + + +P W N L +I + +GSL IE+ +D G
Sbjct: 900 NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSL---HIERVQLQDGG 956
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASEN 1195
Y CVA N AG + V V P ++
Sbjct: 957 EYTCVASNVAGTNNKTTSVVVHVLPTIQH 985
Score = 40.4 bits (93), Expect = 0.016
Identities = 34/150 (22%), Positives = 58/150 (38%), Gaps = 16/150 (10%)
Query: 1694 WQKTGNAVRAIGR----LSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1749
W K G+ V + LS +++ S + S TG T E + D+
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-------- 2096
Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809
+ + +V P +++ V+ A C+ + P P + W KD + + I
Sbjct: 2097 -DLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSI--- 2152
Query: 1810 EDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
+ L I D D +YTC+A N G+
Sbjct: 2153 SENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 39.7 bits (91), Expect = 0.028
Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 3/93 (3%)
Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
V+ + DC + G P P ++W KD Q I E F+I + L+I+ +
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGL 1802
Query: 1829 YTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
Y C A N+ G+ E+ V + G E
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSE 1835
Score = 39.3 bits (90), Expect = 0.036
Identities = 50/227 (22%), Positives = 81/227 (35%), Gaps = 50/227 (22%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
++V V K L++C S P W +G+ L G + + I D
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRI--LQILNTQITD 2937
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
G Y CVA+N AG A+ + N P P V+G +S
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNL---------NVHVP-----------PSVIGPKS------ 2971
Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
E+ V + L +V+G P +W+K + I+ + +
Sbjct: 2972 --------------------ENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNT 3011
Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ G L I+ A+ G YT + N+ G + + +LTV P
Sbjct: 3012 LI--VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056
Score = 38.9 bits (89), Expect = 0.047
Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 6/100 (6%)
Query: 1740 DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
+VS+ F+ V E PH+ S+ ++ V+ + C G P P++ W KD + +
Sbjct: 3514 EVSKHFILKVLEP-PHING--SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLP 3570
Query: 1800 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
++ Q G L IS +D +YTC A + G+
Sbjct: 3571 QTDQVQ---TLGGGEVLRISTAQVEDTGRYTCLASSPAGD 3607
Score = 38.5 bits (88), Expect = 0.062
Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 10/123 (8%)
Query: 1744 AFLEAVAEEKPHVKPYFSKTIR-------DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
A + AE+ HV Y I + +VV + +CK G P P + W KD
Sbjct: 1621 ANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGV 1680
Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 1856
++ + + +I E G L I D +Y C A + GE E+ V EG
Sbjct: 1681 PVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEG 1737
Query: 1857 EGE 1859
E
Sbjct: 1738 GDE 1740
Score = 38.1 bits (87), Expect = 0.081
Identities = 85/475 (17%), Positives = 153/475 (32%), Gaps = 91/475 (19%)
Query: 877 VETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVK-- 934
V+T ++R + +DFR +K + +DF+ + R V+
Sbjct: 299 VKTSSSGRHSVRITGLSTIDFRAGFSRKPT----------------LDFKKTVSRPVQGI 342
Query: 935 PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPA-----TPDFRSVLGGKK 989
P V + +P ++D +L+ G+S +P K P + DF V +
Sbjct: 343 PTYVLLNTSGISTPARIDLLELLSISGSSLKTIPVKYYPHRKPYGIWNISDF--VPPNEA 400
Query: 990 KLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKP 1049
G + L + SS S+ P P + P L+P ++L P
Sbjct: 401 FFLKVTGYDKDDYLFQRV--SSVSFSSIVPDAPKVTMPEKTPGYYLQPGQIPCSVDSLLP 458
Query: 1050 MG--------NAKPDENLKSASKEELK--KDVKND---VNCKRGHAGTTDNEKRSESQGT 1096
D+ LK ++ L K +D C + T +
Sbjct: 459 FTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
P Q +V V G++ +L C + S + W N + ++ + + +L S+
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANL-SLE 577
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
++ D G Y C+ ++ G + S +TV +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQE--------------------------- 610
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
PP++ P++Q G V + TG W
Sbjct: 611 --------------------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
I S ++ + L I A + G Y L N G+ + L ++ P
Sbjct: 651 FIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
Score = 38.1 bits (87), Expect = 0.081
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
++P ++ T + E V F C +G P P + W + + + R I EDG
Sbjct: 1267 LEPPYNTTFQ--ERVANQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTL- 1322
Query: 1816 LIISDVCGDDDAKYTCKAVNSLG 1838
L+I+ V D+ +Y C AVN G
Sbjct: 1323 LVIASVTPYDNGEYICVAVNEAG 1345
Score = 38.1 bits (87), Expect = 0.081
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
G A +C+++G P P + W + I S + + GN SL I +D YTC
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTC 4419
Query: 1832 KAVNSLGEATCTAELIVET 1850
A N G + L +++
Sbjct: 4420 VATNEAGVVERSMSLTLQS 4438
Score = 37.7 bits (86), Expect = 0.11
Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 1735 LESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD 1794
+ SE S A + +E P V + ++ GS C GYP P++ W +
Sbjct: 593 VSSEGGSSAASVFLTVQEPPKV----TVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN 648
Query: 1795 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
D I S +++ D +L I + D Y C A NS G
Sbjct: 649 DMFIVGSHRYRMTSDG----TLFIKNAAPKDAGIYGCLASNSAG 688
Score = 37.0 bits (84), Expect = 0.18
Identities = 57/271 (21%), Positives = 90/271 (33%), Gaps = 60/271 (22%)
Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1136
C +A TD + P+ ++ V + L C+ + P +I W NG
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGH 3842
Query: 1137 TLKT----TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
L + +LS GSL +S +D Y+C N AG + + +TV
Sbjct: 3843 LLNVDQNQNSYRLLS-SGSLVIIS---PSVDDTATYECTVTNGAGDDKRTVDLTV----- 3893
Query: 1193 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1252
+PP + E + K AP A + FP + G
Sbjct: 3894 ----------------QVPPSIADEPTDFLVTKHAPAVITCTASG---VPFPSIHWTKNG 3934
Query: 1253 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1312
+ L + G + + + + ILA + H G YT +
Sbjct: 3935 --IRLLPRGDGYRIL-----------------------SSGAIEILATQLNHAGRYTCVA 3969
Query: 1313 ENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
N GS V L V +PP P S++
Sbjct: 3970 RNAAGSAHRHVTLHV---HEPPVIQPQPSEL 3997
Score = 36.2 bits (82), Expect = 0.31
Identities = 22/97 (22%), Positives = 41/97 (42%), Gaps = 11/97 (11%)
Query: 1751 EEKPHVKPYFSK--------TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1802
E K ++ P +K + +++++ + +C+ P + W+KD Q ++
Sbjct: 2660 EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDD 2719
Query: 1803 HFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
H I +L I + D +YTC A N GE
Sbjct: 2720 HVNI---AANGHTLQIKEAQISDTGRYTCVASNIAGE 2753
Score = 35.8 bits (81), Expect = 0.40
Identities = 22/89 (24%), Positives = 39/89 (43%), Gaps = 6/89 (6%)
Query: 1763 TIRDLEVVEGSAARF--DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
T+ +E V + + +C+ G P P + W + SI + N SL I+D
Sbjct: 4443 TLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL----SNNSLYIAD 4498
Query: 1821 VCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+D +++ C A N +G +IV+
Sbjct: 4499 AQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 35.4 bits (80), Expect = 0.52
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 3/84 (3%)
Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
HV P + + L+V G C +G P P + W K ++ + + DG
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDG-- 1224
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
+L I D YTC A N G
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAG 1248
Score = 35.0 bits (79), Expect = 0.68
Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 1769 VVEGSAARFDCKI-EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
V+EG C + G P PE W K+ + ++ + + D SL I V D
Sbjct: 901 VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG----SLHIERVQLQDGG 956
Query: 1828 KYTCKAVNSLGEATCTAELIVETM 1851
+YTC A N G T ++V +
Sbjct: 957 EYTCVASNVAGTNNKTTSVVVHVL 980
Score = 35.0 bits (79), Expect = 0.68
Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 7/85 (8%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR--ESRHFQIDYDEDGNCSLIISDVCG 1823
++ V+ G C+++ P P + W K+ Q I RH + + S+ I++
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLP-----SGSMKITETRT 1142
Query: 1824 DDDAKYTCKAVNSLGEATCTAELIV 1848
D Y C A N G T +L V
Sbjct: 1143 SDSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 34.7 bits (78), Expect = 0.89
Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
P +K S ++ V+ +A +C G P P W KD Q + E H + + +G
Sbjct: 2869 PIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHK--FLSNGR 2926
Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEA 1840
I++ D +Y C A N+ G A
Sbjct: 2927 ILQILNTQI-TDIGRYVCVAENTAGSA 2952
Score = 34.7 bits (78), Expect = 0.89
Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 7/115 (6%)
Query: 1732 AEKLESEEDVSQAFLEAVAEEKP-HVKPYFSKTIRDLE---VVE--GSAARFDCKIEGYP 1785
AE ++ + V +A A ++K H+ Y +I E +VE + C G P
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIP 3179
Query: 1786 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
P + W K+ + I S ++ G L I+ D YTC A N G+A
Sbjct: 3180 PPTIAWLKNHKRIENSDSLEVRI-LSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 34.3 bits (77), Expect = 1.2
Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 1/80 (1%)
Query: 1761 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
S + L V+EG+ C+ G P P ++W K + ++ G L IS
Sbjct: 2200 SDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGR-QLQISI 2258
Query: 1821 VCGDDDAKYTCKAVNSLGEA 1840
D A Y+C A N G A
Sbjct: 2259 AEKSDAALYSCVASNVAGTA 2278
Score = 34.3 bits (77), Expect = 1.2
Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 3/72 (4%)
Query: 1768 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
+V+ + C+ P P + W+KD + S I G L I +D
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLI---LPGGRVLQIPRAKVEDAG 2844
Query: 1828 KYTCKAVNSLGE 1839
+YTC AVN GE
Sbjct: 2845 RYTCVAVNEAGE 2856
Score = 34.3 bits (77), Expect = 1.2
Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 3/84 (3%)
Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
+V P + L ++ + +C EG P P + W KD ++ H + E+G
Sbjct: 3710 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDG-AVLAGNHARYSILENG-- 3766
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
L I D +Y C A N+ G
Sbjct: 3767 FLHIQSAHVTDTGRYLCMATNAAG 3790
Score = 33.1 bits (74), Expect = 2.6
Identities = 24/95 (25%), Positives = 35/95 (36%), Gaps = 3/95 (3%)
Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
H P +L V+ + C+ G P P + W K+ ++ S G
Sbjct: 3985 HEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-- 4042
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L IS +D Y C A N G A +L V+
Sbjct: 4043 -LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076
Score = 32.3 bits (72), Expect = 4.4
Identities = 19/90 (21%), Positives = 39/90 (43%), Gaps = 16/90 (17%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-------I 1818
++ VV +C+++G P P++ WFKD + + + D N L+ +
Sbjct: 1462 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPL---------FLGDPNVELLDRGQVLHL 1512
Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+ +D +Y C N+ G+ +L +
Sbjct: 1513 KNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 31.6 bits (70), Expect = 7.6
Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
V+ + + +CK G P P + W+KD++ + S + + G + I D
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNRGQI-IDIESAQISDAGI 1988
Query: 1829 YTCKAVNSLG 1838
Y C A+NS G
Sbjct: 1989 YKCVAINSAG 1998
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 171 bits (434), Expect = 5e-42
Identities = 181/790 (22%), Positives = 294/790 (37%), Gaps = 114/790 (14%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
P L + GA + +G P+P +TWH++GQ +T L+ R T L +
Sbjct: 2311 PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR-----LENNSRATRVLRVR---- 2361
Query: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
D G YTC A + +GA + K+ R AP P+I G
Sbjct: 2362 -DAGLYTCLAESPAGA---------------------IEKSFRVRVQAP-----PNIVGP 2394
Query: 159 CPPKFATKL--GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
P+F L G++V++ C + P P++TW + + LQ A E+ +
Sbjct: 2395 RGPRFVVGLAPGQLVLE--------CSVEAEPAPKITWHRDGIVLQEDAHTQFPERG--R 2444
Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD-----------SANRSFVRETK 265
L++ ++ D G Y+C N +G S++ + I + S N++ + +
Sbjct: 2445 FLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQ 2504
Query: 266 ATNSDV-----RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
A RK+ + + + + L + Q G A++ R+
Sbjct: 2505 ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQG 2564
Query: 321 KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPR--------APGLGVLSPSGEERK 372
+ + P AP L T+ + L P+ L G R
Sbjct: 2565 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 2624
Query: 373 RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVK 432
P+ T P Q + VVS + P V V
Sbjct: 2625 LPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVV 2684
Query: 433 FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNA 492
C +GIP P V+W G + + Y + S L + +A +G Y+C+A N+
Sbjct: 2685 LTCHSTGIPAPTVSWSKAGAQLGARGSG---YRVSPSGALEIGQALPIHAGRYTCSARNS 2741
Query: 493 QGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
G L V+ V++ PS + + ++ +L C G P P ITW G
Sbjct: 2742 AGVAHKHVFLTVQASPVVKPLPSVVRAVAE------EEVLLPCEASGIPRPTITWQKEGL 2795
Query: 553 PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL 612
+ ST +L I A PED G Y C+A+N+ G + V
Sbjct: 2796 NVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ----------- 2844
Query: 613 LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE-DFHF 671
P+ GL DL +GS + + G+P P + W +G + +E F
Sbjct: 2845 --------VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTI 2896
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 731
+ G L ++ + +D GTYTC A N+ G R + LT+ P F + P +
Sbjct: 2897 QPSG---ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL-----VLPVFTTLPGDRS 2948
Query: 732 ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 791
LG + + CA G P P + W + + + + V + + TL V +G
Sbjct: 2949 LRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSEQDGGSTLQRAAVSREDSGT 3003
Query: 792 YEILLKNRVG 801
Y +NRVG
Sbjct: 3004 YVCWAENRVG 3013
Score = 169 bits (429), Expect = 2e-41
Identities = 197/775 (25%), Positives = 290/775 (37%), Gaps = 145/775 (18%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
K +T E P P + W+++GQP+T R + + L I D G+Y
Sbjct: 1461 KVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQV---LGEGRLLQIQPTQVSDSGRY 1517
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
C ATN +G + ++ P + + +GD +A + +R E
Sbjct: 1518 LCVATNVAGEDDQDFNVLIQ--------VPPMFQKVGDFSAAFEILSRE----EEARGGV 1565
Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
T+ +V E C P P +TW + + PL VSV + G +VL+I V
Sbjct: 1566 TEYREIV--ENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ--GGRVLQIPLVR 1621
Query: 225 QDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESK 284
++ G Y+C N G+ + EL V D + V V S
Sbjct: 1622 AENAGRYSCKASNEVGEDWLHYEL-----------LVLTPPVILGDTEELVEEVTVNASS 1670
Query: 285 LDSLEAAAKSKNCSSPQRGGSPP---WAANSQPQPPRESKLESCKDSPRTAPQTPVLQKT 341
SL+ P G P W N P P +P LQ
Sbjct: 1671 TVSLQC---------PALGNPVPTISWLQNGLPFSP-----------------SPRLQVL 1704
Query: 342 SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR 401
LQ + + A + V ++ R P R GL + V +
Sbjct: 1705 EDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLR-VQVPPRIAGLDLEQVTAIL--- 1760
Query: 402 RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI 461
N +V C+V P PEV W+ + + E
Sbjct: 1761 --------------------------NSSVSLPCDVHAHPNPEVTWYKDSQALSLGE--- 1791
Query: 462 EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLK 521
EV+ G+H L L +AR DSG Y+C A NA G+ ++ +L+V+ V P+F +
Sbjct: 1792 EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGR-----DQKLVQLSVL-VPPAFRQAPR 1845
Query: 522 ---DCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPE 576
D ++ G VL C P P +TW +GQP+ A R+ G L IQ+A
Sbjct: 1846 GPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS 1905
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
D G Y+C N G+ + +TV +P P Q +
Sbjct: 1906 DKGLYSCKVSNVAGEAVRTFTLTVQ-----------VPPTFENPKTETVSQ-------VA 1947
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
GS + +T VSG P P V WL + ++ S RG + L + + P GTYTC
Sbjct: 1948 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGR--LQLSRLQPAQAGTYTCV 2005
Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL--------GQSVLISCAIAGDP 748
A N+ E R V+ V + PR ++ + GQ V + C G P
Sbjct: 2006 AENTQAEARKDFVVAV-----------LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQP 2054
Query: 749 FPTVHWLRDGKALCKDTG-HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
P V WL+DG L +D G H D +LVLK ++ AG Y + N GE
Sbjct: 2055 PPDVAWLKDGSPLGQDMGPHLRFYL--DGGSLVLKGLRASDAGAYTCVAHNPAGE 2107
Score = 148 bits (373), Expect = 6e-35
Identities = 110/380 (28%), Positives = 175/380 (46%), Gaps = 44/380 (11%)
Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
C+ G P+P + W +G PV EG + S L + +D+GTY+CTA NA G
Sbjct: 2868 CKARGSPEPNITWDKDGQPVSGAEGKFTIQP---SGELLVKNLEGQDAGTYTCTAENAVG 2924
Query: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
+ L + V P F+++ D ++ G L+C+ RG+P PRI W +N +P+
Sbjct: 2925 RARRRVHLTIL------VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPV 2978
Query: 555 QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP 614
S + G + L ED GTY C AEN +G+ ++V V E
Sbjct: 2979 TEGVSEQDGG-STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKE------------ 3025
Query: 615 VAPSKPTAPIFLQG--LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 672
AP+ LQG S L G + + V G+P P++ W+ +G ++ S H
Sbjct: 3026 -------APV-LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQL 3077
Query: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTA 732
Q G SL I +D G Y C A N G + +L +Q + P F +P+ +T
Sbjct: 3078 QNG---SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQ-----SAPVFQVEPQDMTV 3129
Query: 733 SLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
G V + C G+P PT+ WL+ G+ L + + L + +L L+ V+ AG Y
Sbjct: 3130 RSGDDVALRCQATGEPTPTIEWLQAGQPL-RASRRLRTLPDG---SLWLENVETGDAGTY 3185
Query: 793 EILLKNRVGECSCQVSLMLQ 812
+ + N +G + + L+++
Sbjct: 3186 DCVAHNLLGSATARAFLVVR 3205
Score = 145 bits (366), Expect = 4e-34
Identities = 120/405 (29%), Positives = 178/405 (43%), Gaps = 44/405 (10%)
Query: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
A P + P + V CE SGIP+P + W EG V + +
Sbjct: 2755 ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVST----QVLPGGQ 2810
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
L + A D+G Y C A N+ G L V++V P + L D + EG
Sbjct: 2811 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRL------VVQVPPVIENGLPDLSTTEGSHA 2864
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA-ELHIQDALPEDHGTYTCLAENALG 590
L C RG+P P ITW +GQP+ A + EL +++ +D GTYTC AENA+G
Sbjct: 2865 FLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG 2924
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
+ +T+ +LPV + P D + G ++ + G+P
Sbjct: 2925 RARRRVHLTI----------LVLPVFTTLP---------GDRSLRLGDRLWLRCAARGSP 2965
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
P + W N + E EQ G +L V ED+GTY C A N G RTQAV
Sbjct: 2966 TPRIGWTVNDRPVTEGVS---EQDGGS-TLQRAAVSREDSGTYVCWAENRVG--RTQAVS 3019
Query: 711 TVQEPHDGTQPWFISKPRS-VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
V H P + S + +G S+ + C + GDP P +HW++DG L + +
Sbjct: 3020 FV---HVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL-RGSHLRH 3075
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
LQN +L + + + AG+Y+ L +N +G V L+LQ++
Sbjct: 3076 QLQNG---SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSA 3117
Score = 138 bits (347), Expect = 6e-32
Identities = 185/745 (24%), Positives = 273/745 (36%), Gaps = 117/745 (15%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCG---IRG 87
E PA P NL + A G P+P V W ++GQ + F L G +
Sbjct: 2571 EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLD----FRLQQGAYRLLP 2626
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
+ +L++ A +D ++ C +N G ++TV
Sbjct: 2627 SNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH----------------------- 2663
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
P+I + T + VV+ +C TG P P V+W K L AR
Sbjct: 2664 ---VPPTIADDQTDFTVTMMAPVVL--------TCHSTGIPAPTVSWSKAGAQL--GARG 2710
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------LDSANRSFV 261
S + LEI G YTC N +G A L++Q L S R+
Sbjct: 2711 SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVA 2770
Query: 262 RETKATNSDV----------RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
E + +KE NV + S + + S G A N
Sbjct: 2771 EEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKN 2830
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA--ARVQPEPR------------ 357
S +++L + P P L T S AR PEP
Sbjct: 2831 SAGSAMGKTRLV-VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG 2889
Query: 358 APGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFE 417
A G + PSGE + + A T +++ V +A RR+ + P F
Sbjct: 2890 AEGKFTIQPSGELLVKNLEGQDAGTYT----CTAENAVGRA-RRRVHLT---ILVLPVFT 2941
Query: 418 SKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKA 477
+ P + ++ + RC G P P + W + PV EG V E G L
Sbjct: 2942 TLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVT--EG---VSEQDGGSTLQRAAV 2996
Query: 478 RTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
DSGTY C A N G+ + V+ V++ +FS +++ G L C V
Sbjct: 2997 SREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQ-GEAFSYLVEPV----GGSIQLDCVV 3051
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
RG PVP I W+ +G P++ + + L I +D G Y CLAEN +G
Sbjct: 3052 RGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVA----- 3106
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
K +L + +AP+F D+ V G V + Q +G P P + WL
Sbjct: 3107 ----------KKVVILVL----QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL 3152
Query: 658 HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ-EPH 716
G ++ S G SL ++ V D GTY C A N G +A L V+ EP
Sbjct: 3153 QAGQPLRASRRLRTLPDG---SLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3209
Query: 717 D--GTQPWFISKPRSVTASLGQSVL 739
G+ I+ + A+L SV+
Sbjct: 3210 GSWGSMTGVINGRKFGVATLNTSVM 3234
Score = 134 bits (337), Expect = 8e-31
Identities = 186/829 (22%), Positives = 286/829 (34%), Gaps = 196/829 (23%)
Query: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV 117
G P P + W +NG+P + +GT +L I V + G + C+ATN +G
Sbjct: 524 GSPVPTIQWLQNGRPAEELAG--VQVASQGT-TLHIDHVELDHSGLFACQATNEAGTAGA 580
Query: 118 TVELTVEGSFAK-----QLGQ----------------PVVSKTLGDRFSAPAVE---TRP 153
VE++V G +A +GQ P V + G P VE +
Sbjct: 581 EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPG 640
Query: 154 SIWGE-----------------------------------------------CPPKFATK 166
S+WGE PP
Sbjct: 641 SLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPG 700
Query: 167 LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226
V E C +G P P V+W KG+ P+ V+VS +VL I
Sbjct: 701 PVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLS 758
Query: 227 DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLD 286
D G Y C+ N +G + L + NV + +
Sbjct: 759 DAGSYRCVASNVAGSTELRYGLRV--------------------------NVPPRITLPP 792
Query: 287 SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSS-- 344
SL P +P + P + + +P + TP LQ
Sbjct: 793 SL---------PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV 843
Query: 345 ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPG--LGSQDVVSKAANRR 402
+TL +AR R + V S GE+R + P LG + VS AN
Sbjct: 844 LTLASARASDSGRYSCVAV-SAVGEDR------QDVVLQVHMPPSILGEELNVSVVANES 896
Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
+ +E Q + +P P ++W+ +G P+ + G
Sbjct: 897 VALECQSHA----------------------------MPPPVLSWWKDGRPLEPRPG--- 925
Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
V+ A L + +A D+G Y+C A N G+ + L V V + S + ++
Sbjct: 926 VHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVR- 984
Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHG 579
EG L C RG P P+I+W +GQP+ + + A L++ A G
Sbjct: 985 ----EGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 1040
Query: 580 TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 639
TYTC N +G S + VH +P + P P + + V+
Sbjct: 1041 TYTCECSNVVGNSSQDLQLEVH-----------VPPQIAGPREP-----PTQVSVVQDGV 1084
Query: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
T+ +G PPP V W +G + + +G SL ++ TG Y+C A N
Sbjct: 1085 ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG--QSLHVERAQAAHTGRYSCVAEN 1142
Query: 700 SAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
AG + L+V P + + ++TA+L + + C G P P + W R
Sbjct: 1143 LAGRAERKFELSVLVPPELIGD--LDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR--- 1197
Query: 760 ALCKDTGHFEVLQNEDVFTLV------LKKVQPWHAGQYEILLKNRVGE 802
G V ED + L + + Q +G Y L N GE
Sbjct: 1198 ------GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGE 1240
Score = 128 bits (322), Expect = 5e-29
Identities = 110/377 (29%), Positives = 156/377 (41%), Gaps = 44/377 (11%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V V+ CE G+P P V+W +G P+ Q E S L L DSGT
Sbjct: 2227 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQS-----LEQGPS--LQLEAVGAGDSGT 2279
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
YSC A + G+ + L V +E S + ++ G L C +GTP P
Sbjct: 2280 YSCVAVSEAGEARRHFQLTVMEPPHIED----SGQPTELSLTPGAPMELLCDAQGTPQPN 2335
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
ITW +GQ + + A L ++DA G YTCLAE+ G + S V V
Sbjct: 2336 ITWHKDGQALTRLENNSRA-TRVLRVRDA-----GLYTCLAESPAGAIEKSFRVRVQA-- 2387
Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
P P P F+ GL+ Q+ + V P P++ W +G +Q
Sbjct: 2388 ---------PPNIVGPRGPRFVVGLAP------GQLVLECSVEAEPAPKITWHRDGIVLQ 2432
Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
E F +RG L +Q + D+G Y+C A N+AG + + T P
Sbjct: 2433 EDAHTQFPERG--RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-----TVPTIR 2485
Query: 725 SKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKV 784
S P +V S+ Q+ L+ C G P P V W +D L + FE+L +L ++ V
Sbjct: 2486 SGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPV 2542
Query: 785 QPWHAGQYEILLKNRVG 801
AG Y L N G
Sbjct: 2543 LAQDAGHYLCLASNSAG 2559
Score = 128 bits (321), Expect = 6e-29
Identities = 116/443 (26%), Positives = 177/443 (39%), Gaps = 43/443 (9%)
Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
V+ +C SG+P P+V W + PV ++V ED L + + D G Y C A
Sbjct: 235 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDG--QVLRITGSHVGDEGRYQCVAF 292
Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSF--SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 548
+ GQ + + L+V P+ S+ + AV+E L C RG P P ITW
Sbjct: 293 SPAGQQARDFQLRVH------APPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWF 346
Query: 549 LNGQPIQYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607
+G + + G +L + A D G YTC A NA+G +K++R
Sbjct: 347 KDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAA----------EKATR 396
Query: 608 KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
Y+ P P + K + G V + G+P P + W H G + ES
Sbjct: 397 LDVYVPPTIEGAGGRPYVV------KAVAGRPVALECVARGHPSPTLSWHHEGLPVAESN 450
Query: 668 DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP 727
+ E G+ L ++ +G Y+C A + AGE Q + VQ P Q
Sbjct: 451 ESRLETDGSV--LRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVP---PQLLVAEGL 505
Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 787
VT +GQ + + C +G P PT+ WL++G+ + G Q TL + V+
Sbjct: 506 GQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT---TLHIDHVELD 562
Query: 788 HAGQYEILLKNRVGECSCQVSLMLQNSSARA---LPRGREPASCEDLCGGGVGAD----- 839
H+G + N G +V + + A +P G+ E D
Sbjct: 563 HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 622
Query: 840 GGGSDRYGSLRPGWPARGQGWLE 862
G G+ L GW + G W E
Sbjct: 623 GWGAHPKPPLVEGWCSPGSLWGE 645
Score = 126 bits (316), Expect = 2e-28
Identities = 105/399 (26%), Positives = 166/399 (41%), Gaps = 47/399 (11%)
Query: 413 FPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472
FP ES + V+E CE G+P P+++W +G P+ + ++ + A L
Sbjct: 973 FPLRES--HTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQ-HVSAVGRLL 1029
Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE---RLAVMEVAPSFSSVLKDCAVIEGQ 529
L +A+ GTY+C SN G S L+V ++A P+ SV++D
Sbjct: 1030 YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVA---- 1085
Query: 530 DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV------AELHIQDALPEDHGTYTC 583
L+C+ G P P +TW +GQP+ E G+ LH++ A G Y+C
Sbjct: 1086 --TLECNATGKPPPTVTWERDGQPV-----GAELGLQLQNQGQSLHVERAQAAHTGRYSC 1138
Query: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
+AEN G ++ RK E + V P L L+++ S +T+
Sbjct: 1139 VAENLAG-------------RAERKFELSVLVPPELIGD---LDPLTNITAALHSPLTLL 1182
Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
+ G PPP + W + ED + G L + + +D+G Y+C A N AGE
Sbjct: 1183 CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWM--LKMTQTQEQDSGLYSCLASNEAGE 1240
Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
R + V P + GQ+ + C + G P P + W +DG+ L +
Sbjct: 1241 ARRNFSVEVLVPPSIENE---DLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLAR 1297
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
H + D L + + AG Y + N VGE
Sbjct: 1298 GDAHH---ISPDGVLLQVLQANLSSAGHYSCIAANAVGE 1333
Score = 124 bits (311), Expect = 9e-28
Identities = 113/433 (26%), Positives = 165/433 (38%), Gaps = 53/433 (12%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P E P ++ V EN +V C SG+P P+V+WF PV G V L
Sbjct: 695 PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTVSVDGRVLR 751
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
+ +A+ D+G+Y C ASN G + L+V + + PS V+ L
Sbjct: 752 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPG-----PVLVNTPVRL 806
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
C+ G P P + WL +G P+ A + G L + A D G Y+C+A +A+G
Sbjct: 807 TCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVG 866
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
+ + VH P L ++ V+ V + Q P
Sbjct: 867 EDRQDVVLQVH-------------------MPPSILGEELNVSVVANESVALECQSHAMP 907
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
PP + W +G ++ H + L + D G YTCEA N AG
Sbjct: 908 PPVLSWWKDGRPLEPRPGVHLS--ADKALLQVDRADVWDAGHYTCEALNQAGR------- 958
Query: 711 TVQEPHDGTQPWF-----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
E H W + + ++T G +SC G PFP + W +DG+ L
Sbjct: 959 --SEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL---P 1013
Query: 766 GHFEVLQNEDVF--TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGR 823
G LQ+ L L + Q G Y N VG S + L + A P R
Sbjct: 1014 GEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGP--R 1071
Query: 824 EPASCEDLCGGGV 836
EP + + GV
Sbjct: 1072 EPPTQVSVVQDGV 1084
Score = 119 bits (298), Expect = 3e-26
Identities = 109/396 (27%), Positives = 163/396 (41%), Gaps = 40/396 (10%)
Query: 423 QEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
+E+ EN C+ + IP P++ W+ E P+ + EV G L + R ++
Sbjct: 1569 REIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGD---EVSVLQGGRVLQIPLVRAENA 1625
Query: 483 GTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
G YSC ASN G+ + L V L + ++++ V LQC G PV
Sbjct: 1626 GRYSCKASNEVGEDWLHYELLV--LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPV 1683
Query: 543 PRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
P I+WL NG P + E G L + A D +Y C+AEN G
Sbjct: 1684 PTISWLQNGLPFSPSPRLQVLEDGQV-LQVSTAEVADAASYMCVAENQAG---------- 1732
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
+E L + P L L + + S V++ V +P PEV W +
Sbjct: 1733 -------SAEKLFTLRVQVPPRIAGLD-LEQVTAILNSSVSLPCDVHAHPNPEVTWYKDS 1784
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
+ E+ F GT H+L + D+G YTCEA N+AG + L+V P
Sbjct: 1785 QALSLGEEV-FLLPGT-HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP----- 1837
Query: 721 PWFISKPR----SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
P F PR +V +G ++SC P PTV W +DG+ L + L+
Sbjct: 1838 PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVL-AQRTQALRGGQ- 1895
Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
L +++ Q G Y + N GE +L +Q
Sbjct: 1896 -RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ 1930
Score = 119 bits (297), Expect = 4e-26
Identities = 99/385 (25%), Positives = 157/385 (40%), Gaps = 45/385 (11%)
Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
C V P P++ W +G + QE + + + G +L L T DSG YSCTA NA G
Sbjct: 2412 CSVEAEPAPKITWHRDGIVL--QEDAHTQFPERG-RFLQLQALSTADSGDYSCTARNAAG 2468
Query: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
S ++ +++ + + P +V + Q +L C G P P ++W + P+
Sbjct: 2469 STSVAFRVEIHTVPTIRSGPPAVNVSVN------QTALLPCQADGVPAPLVSWRKDRVPL 2522
Query: 555 QYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 613
E L IQ L +D G Y CLA N+ G S R+ L
Sbjct: 2523 DPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG--------------SDRQGRDLR 2568
Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673
+ P P S+L + + + + SG+P P V+W +G ++ DF +Q
Sbjct: 2569 VLEP-----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL----DFRLQQ 2619
Query: 674 RGTQ----HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729
+ ++L + P+D+ + C N GE +TV P P
Sbjct: 2620 GAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVP-----PTIADDQTD 2674
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
T ++ V+++C G P PTV W + G L + V + L + + P HA
Sbjct: 2675 FTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHA 2731
Query: 790 GQYEILLKNRVGECSCQVSLMLQNS 814
G+Y +N G V L +Q S
Sbjct: 2732 GRYTCSARNSAGVAHKHVFLTVQAS 2756
Score = 118 bits (296), Expect = 5e-26
Identities = 106/388 (27%), Positives = 155/388 (39%), Gaps = 48/388 (12%)
Query: 419 KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
+P + ++ C+ G P+P + W +G + R E + R
Sbjct: 2310 QPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR----------VLR 2359
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
RD+G Y+C A + G + S+ ++V+ + V P + A GQ VL+CSV
Sbjct: 2360 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLA--PGQ-LVLECSVE 2415
Query: 539 GTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
P P+ITW +G +Q A + L +Q D G Y+C A NA G S +
Sbjct: 2416 AEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFR 2475
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
V +H T P G + V + Q G P P V W
Sbjct: 2476 VEIH-------------------TVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWR 2516
Query: 658 HNGNEIQ-ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716
+ + S F G SL IQ V +D G Y C A NSAG R L V EP
Sbjct: 2517 KDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEP- 2572
Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL--CKDTGHFEVLQNE 774
P P ++T + L+ C +G P P V W +DG+ L G + +L +
Sbjct: 2573 ----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 2628
Query: 775 DVFTLVLKKVQPWHAGQYEILLKNRVGE 802
L+L P + Q+E ++ N VGE
Sbjct: 2629 ---ALLLTAPGPQDSAQFECVVSNEVGE 2653
Score = 117 bits (293), Expect = 1e-25
Identities = 108/407 (26%), Positives = 169/407 (41%), Gaps = 39/407 (9%)
Query: 414 PKFESKPQSQEVK--ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
P E++ + +K + QT C V+G P+P++ WF +G P+ R + +
Sbjct: 1253 PSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAH---HISPDGVL 1309
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
L +L+A +G YSC A+NA G+ + + L V LA + + S ++ V
Sbjct: 1310 LQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV-LLAPTILGGAEDSADEEVTVTVNNPI 1368
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
L C P P ITW+ +G P + +R+ G L I +A ED G YTC+ N LG
Sbjct: 1369 SLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 1428
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
E + E L+P + SK P+ G+ ++K S +T+ + P
Sbjct: 1429 -----------EAVKNYHVEVLIPPSISKDD-PLGEVGVKEVKTKVNSTLTLECESWAVP 1476
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE------V 704
PP + W +G + S + G L IQ D+G Y C A N AGE V
Sbjct: 1477 PPTIRWYKDGQPVTPSS--RLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNV 1534
Query: 705 RTQAVLTVQEPHDGTQPW-FISKPRSVTASL--------GQSVLISCAIAGDPFPTVHWL 755
Q Q+ D + + +S+ + + C P P + W
Sbjct: 1535 LIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWY 1594
Query: 756 RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
R+ + L VLQ V + L + + +AG+Y N VGE
Sbjct: 1595 REDQPLSAG-DEVSVLQGGRVLQIPLVRAE--NAGRYSCKASNEVGE 1638
Score = 117 bits (292), Expect = 1e-25
Identities = 105/406 (25%), Positives = 158/406 (38%), Gaps = 50/406 (12%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P S P + V NQT C+ G+P P V+W + P+ + E+ + L
Sbjct: 2482 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS---LR 2538
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
+ +D+G Y C ASN+ G L+V L +APS S++ + +L
Sbjct: 2539 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRV--LEPPAIAPSPSNL----TLTAHTPALL 2592
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDAL------PEDHGTYTCLAEN 587
C G+P P + W +GQ + + + G L +AL P+D + C+ N
Sbjct: 2593 PCEASGSPKPLVVWWKDGQKLDF---RLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 2649
Query: 588 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
+G+ VTVH P +D V + V +T +
Sbjct: 2650 EVGEAHRLYQVTVH-------------------VPPTIADDQTDFTVTMMAPVVLTCHST 2690
Query: 648 GNPPPEVIWLHNGNEI-QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 706
G P P V W G ++ + G +L I + P G YTC A NSAG
Sbjct: 2691 GIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHAGRYTCSARNSAGVAHK 2747
Query: 707 QAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG 766
LTVQ P P V A + VL+ C +G P PT+ W ++G +
Sbjct: 2748 HVFLTVQ-----ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVS 2802
Query: 767 HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
+VL L + P AG Y + KN G + L++Q
Sbjct: 2803 -TQVLPGGQ---LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 2844
Score = 115 bits (289), Expect = 3e-25
Identities = 92/379 (24%), Positives = 158/379 (41%), Gaps = 42/379 (11%)
Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTY 485
+ + V C V G P V+W +G P+ + ++ H L + K + D+G +
Sbjct: 2135 RPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL---HGSGHTLRISKVQLADAGIF 2191
Query: 486 SCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRI 545
+C A++ G ++TLQV+ V+E D V+ G L C RG P+P +
Sbjct: 2192 TCVAASPAGVADRNFTLQVQVPPVLEPV----EFQNDVVVVRGSLVELPCEARGVPLPLV 2247
Query: 546 TWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
+W+ +G+P+ + E G L ++ D GTY+C+A + G+ +TV E
Sbjct: 2248 SWMKDGEPL--LSQSLEQG-PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 2304
Query: 606 SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
S +PT +L + G+ + + G P P + W +G +
Sbjct: 2305 IEDS--------GQPT---------ELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR 2347
Query: 666 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
E+ +S + + D G YTC A + AG + + VQ P + P
Sbjct: 2348 LEN---------NSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGP---R 2395
Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
PR V +++ C++ +P P + W RDG L +D H + + L L+ +
Sbjct: 2396 GPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQED-AHTQFPERGRF--LQLQALS 2452
Query: 786 PWHAGQYEILLKNRVGECS 804
+G Y +N G S
Sbjct: 2453 TADSGDYSCTARNAAGSTS 2471
Score = 114 bits (285), Expect = 9e-25
Identities = 105/389 (26%), Positives = 167/389 (42%), Gaps = 45/389 (11%)
Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
CE GIP P + WF PV E + Y AG L + + + +DSG YSC ASN G
Sbjct: 1183 CEAMGIPPPAIRWFRGEEPVSPGE---DTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 1239
Query: 495 QLSCSWTLQVERLAVMEVAPSFSS--VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
+ +++++V V PS + + + V++GQ L C+V G P P++TW +G+
Sbjct: 1240 EARRNFSVEV------LVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGR 1293
Query: 553 PIQY--ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
P+ A GV L + A G Y+C+A NA+G EK +
Sbjct: 1294 PLARGDAHHISPDGVL-LQVLQANLSSAGHYSCIAANAVG-----------EKTKHFQLS 1341
Query: 611 YLLPVAPSKPTAPIFLQGLSD-----LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
LL AP L G D + V + +++ + P P + W+ +G +
Sbjct: 1342 VLL--------APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEA 1393
Query: 666 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPH-DGTQPWF 723
S + GT H L I ED G YTC N GE V+ V + P P
Sbjct: 1394 SRNIQL-LPGT-HGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLG 1451
Query: 724 ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKK 783
+ V + ++ + C P PT+ W +DG+ + + +VL + L ++
Sbjct: 1452 EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPV-TPSSRLQVLGEGRL--LQIQP 1508
Query: 784 VQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
Q +G+Y + N GE ++++Q
Sbjct: 1509 TQVSDSGRYLCVATNVAGEDDQDFNVLIQ 1537
Score = 110 bits (274), Expect = 2e-23
Identities = 78/289 (26%), Positives = 125/289 (43%), Gaps = 26/289 (8%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V E+ V+ CE G+P P + WF +G + S +V G L L +A++ D+G
Sbjct: 323 VMEDHLVQLLCEARGVPTPNITWFKDGALLPT---STKVVYTRGGRQLQLGRAQSSDAGV 379
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+C ASNA G + L V +E A V+K + G+ L+C RG P P
Sbjct: 380 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVK---AVAGRPVALECVARGHPSPT 436
Query: 545 ITWLLNGQPIQYAR-STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
++W G P+ + S E + L ++ G Y+C+A + G+ V V
Sbjct: 437 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQV- 495
Query: 604 KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI 663
P + +GL + + G + + Q SG+P P + WL NG
Sbjct: 496 ----------------PPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPA 539
Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+E +GT +L I V + +G + C+A N AG + ++V
Sbjct: 540 EELAGVQVASQGT--TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 586
Score = 106 bits (264), Expect = 2e-22
Identities = 121/509 (23%), Positives = 192/509 (37%), Gaps = 60/509 (11%)
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
+ K N T+ CE +P P + W+ +G PV ++V + L + + DSG
Sbjct: 1459 KTKVNSTLTLECESWAVPPPTIRWYKDGQPVT-PSSRLQVLGEG--RLLQIQPTQVSDSG 1515
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA--------------VIEGQ 529
Y C A+N G+ + + ++ + + FS+ + + ++E
Sbjct: 1516 RYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 1575
Query: 530 DFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
L C P P +TW QP+ + G L I E+ G Y+C A N
Sbjct: 1576 PAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNE 1635
Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL----QGLSDLKVMDGSQVTMTV 644
+G+ W+ Y L V T P+ L + + ++ V S V++
Sbjct: 1636 VGE----DWL-----------HYELLVL----TPPVILGDTEELVEEVTVNASSTVSLQC 1676
Query: 645 QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
GNP P + WL NG S + G + EV D +Y C A N AG
Sbjct: 1677 PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV--ADAASYMCVAENQAGSA 1734
Query: 705 RTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
L VQ P P VTA L SV + C + P P V W +D +AL
Sbjct: 1735 EKLFTLRVQVP-----PRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSL 1789
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL-MLQNSSARALPRG 822
EV TL L + + +G Y N G V L +L + R PRG
Sbjct: 1790 GE---EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRG 1846
Query: 823 REPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH 882
+ A + G +D W GQ + + + +RG + ++ Q
Sbjct: 1847 PQDAVLVRV--GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQV 1904
Query: 883 TEEAIRQQEVEQLDFRDLLGKKVSTKTLS 911
+++ + +V ++ G+ V T TL+
Sbjct: 1905 SDKGLYSCKVS-----NVAGEAVRTFTLT 1928
Score = 96.7 bits (239), Expect = 2e-19
Identities = 107/408 (26%), Positives = 149/408 (36%), Gaps = 33/408 (8%)
Query: 419 KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
+P + + V C G P P ++W EG PV E + E GS L L
Sbjct: 411 RPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVA--ESNESRLETDGS-VLRLESPG 467
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
SG YSC AS+ G+ ++++V+ + VA V I GQ L C
Sbjct: 468 EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQV----TTIVGQPLELPCQAS 523
Query: 539 GTPVPRITWLLNGQPIQYARSTCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
G+PVP I WL NG+P + A LHI + G + C A N G
Sbjct: 524 GSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVE 583
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPI-----FLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
V+VH + AP PI + S V PP
Sbjct: 584 VSVHGE-----------WAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPL 632
Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
W G+ E L I++V D G YTC A N AGE + + L V
Sbjct: 633 VEGWCSPGSLWGEPTGIPVAY-SLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKV 691
Query: 713 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
P +P ++K A SV + C +G P P V W + + + G V
Sbjct: 692 LVP-PNIEPGPVNKAVLENA----SVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTV 743
Query: 773 NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
+ D L +++ Q AG Y + N G + L + LP
Sbjct: 744 SVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLP 791
Score = 86.7 bits (213), Expect = 2e-16
Identities = 100/383 (26%), Positives = 142/383 (37%), Gaps = 33/383 (8%)
Query: 435 CEVSGIPKPEVAWFL--EGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNA 492
C G PKP+V W P+ Q G + V E+ L L DSG Y C A+N
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPG-VAVLEEGS---LFLASVSPADSGDYECQATNE 79
Query: 493 QGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAV--IEGQDFVLQCSVRGTPVPRITWL-- 548
G S L V+ V PS + V + GQ L+C G PVP I WL
Sbjct: 80 VGSTSRRAKL------VVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKD 133
Query: 549 --LNGQPIQYARSTCEAGVAELHIQDALPEDHGT-YTCLAENALGQVSCSAWVTVHEKKS 605
L G P+ +A + G ++ L E + + G+ A + K
Sbjct: 134 AQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQPGRSGRRGAQAGGSAQTKAP 193
Query: 606 -----SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD--GSQVTMTVQVSGNPPPEVIWLH 658
+ ++ P A S P P L + +V+ G+ V + SG P P+V W
Sbjct: 194 WXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTK 253
Query: 659 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718
+ + H + + L I D G Y C A++ AG+ L V P
Sbjct: 254 DRQPVLPGGP-HLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAP--- 309
Query: 719 TQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT 778
W ++ V V + C G P P + W +DG L T +V+
Sbjct: 310 PTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTST---KVVYTRGGRQ 366
Query: 779 LVLKKVQPWHAGQYEILLKNRVG 801
L L + Q AG Y N VG
Sbjct: 367 LQLGRAQSSDAGVYTCKASNAVG 389
Score = 85.1 bits (209), Expect = 6e-16
Identities = 95/414 (22%), Positives = 150/414 (36%), Gaps = 61/414 (14%)
Query: 429 QTVKFRCEVSGIPKPEVAWF----LEGTPVR----------RQEGSIEVYEDAGS-HYLC 473
Q++ C+ +G P PE+ W L G P+ Q G + ++ S H+
Sbjct: 112 QSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPR 171
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS-----SVL-----KDC 523
+ R+ G + Q W + +FS SVL ++
Sbjct: 172 IQPGRSGRRG----AQAGGSAQTKAPWXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEV 227
Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTY 581
+ G D LQC G P P++ W + QP+ + L I + D G Y
Sbjct: 228 LGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRY 287
Query: 582 TCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG---LSDLKVMDGS 638
C+A + GQ + + VH AP + G ++ VM+
Sbjct: 288 QCVAFSPAGQQARDFQLRVH--------------------APPTIWGSNETGEVAVMEDH 327
Query: 639 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
V + + G P P + W +G + S + + G Q L + D G YTC+A
Sbjct: 328 LVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQ--LQLGRAQSSDAGVYTCKAS 385
Query: 699 NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDG 758
N+ G L V P T +P V A G+ V + C G P PT+ W +G
Sbjct: 386 NAVGAAEKATRLDVYVP--PTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEG 443
Query: 759 KALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
+ + E D L L+ +G Y + + GE Q S+ +Q
Sbjct: 444 LPVAESN---ESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 494
Score = 77.0 bits (188), Expect = 2e-13
Identities = 95/394 (24%), Positives = 136/394 (34%), Gaps = 60/394 (15%)
Query: 429 QTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCT 488
Q ++ C+ SG P P + W G P G + H + SG ++C
Sbjct: 514 QPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLH---IDHVELDHSGLFACQ 570
Query: 489 ASNAQGQLSCSWTLQVERLAVMEVAPSFSSV---LKDCAVIEGQDFVLQCS--------- 536
A+N G +VE E AP V F C
Sbjct: 571 ATNEAGTAGA----EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGA 626
Query: 537 ------VRGTPVPRITW-LLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
V G P W G P+ Y+ L I+ D G YTC A N
Sbjct: 627 HPKPPLVEGWCSPGSLWGEPTGIPVAYSLPP------PLQIEKVDLRDEGIYTCAATNLA 680
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G+ S R+ + V P+ P+ + V++ + VT+ SG
Sbjct: 681 GE-------------SKREVALKVLVPPNIEPGPV------NKAVLENASVTLECLASGV 721
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
PPP+V W + G L I++ D G+Y C A N AG +
Sbjct: 722 PPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLSDAGSYRCVASNVAGSTELRYG 779
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC-KDTGHF 768
L V P T P + P V V ++C G P PT+ WL+DG + T
Sbjct: 780 LRVNVPPRITLPPSLPGPVLVNT----PVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGL 835
Query: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
+V V TL + +G+Y + + VGE
Sbjct: 836 QVFPGGRVLTLASARAS--DSGRYSCVAVSAVGE 867
Score = 73.9 bits (180), Expect = 1e-12
Identities = 59/214 (27%), Positives = 86/214 (40%), Gaps = 42/214 (19%)
Query: 33 PAFILPPRN----LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
PAF PR + ++ G A PEP VTW+++GQP+ R +RG
Sbjct: 1838 PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQR---TQALRGG 1894
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
L I D+G Y+C+ +N +G T LTV+ + F P
Sbjct: 1895 QRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ---------------VPPTFENPK 1939
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
ET + G P T C ++G P P VTWLK +P++ SA
Sbjct: 1940 TETVSQVAGS--PLVLT----------------CDVSGVPAPTVTWLKDRMPVESSAVHG 1981
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
V + G L++ + G YTC+ N +A
Sbjct: 1982 VVSRGGR--LQLSRLQPAQAGTYTCVAENTQAEA 2013
Score = 72.0 bits (175), Expect = 5e-12
Identities = 59/207 (28%), Positives = 83/207 (40%), Gaps = 42/207 (20%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLL---DCGIRGTFSLVIHAVHEEDRGK 103
GA + + G P PQV W ++ QP+ GG L D + L I H D G+
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV-----LRITGSHVGDEGR 286
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C A + +G + +L V AP P+IWG
Sbjct: 287 YQCVAFSPAGQQARDFQLRVH---------------------AP-----PTIWG------ 314
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
+ + G V V E + + C+ G P P +TW K L S +V V + G Q L++
Sbjct: 315 SNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKV-VYTRGGRQ-LQLGRA 372
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSI 250
D GVYTC N G A + L +
Sbjct: 373 QSSDAGVYTCKASNAVGAAEKATRLDV 399
Score = 69.3 bits (168), Expect = 3e-11
Identities = 57/220 (25%), Positives = 84/220 (38%), Gaps = 35/220 (15%)
Query: 32 APAFIL-PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
AP F L L ++EG RG P P+++W ++GQP+ G L G
Sbjct: 970 APVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL- 1028
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + G YTCE +N G ++L V
Sbjct: 1029 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQL--------------------------EVH 1062
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
P I G P VV++G + C TG+P P VTW + P+ A + +
Sbjct: 1063 VPPQIAGPREPPTQVS----VVQDG-VATLECNATGKPPPTVTWERDGQPV--GAELGLQ 1115
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+N Q L + G Y+C+ N +G+A ELS+
Sbjct: 1116 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSV 1155
Score = 68.6 bits (166), Expect = 6e-11
Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 48/246 (19%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
A + + +T +V V P+ + AF L G + + + VRG P P + W
Sbjct: 3008 AENRVGRTQ-AVSFVHVKEAPVLQGEAFSY----LVEPVGGSIQLDCVVRGDPVPDIHWI 3062
Query: 68 RNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
++G P+ R L G SL IH +D G+Y C A N G + V L ++
Sbjct: 3063 KDGLPLRGSHLRHQLQNG-----SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQ-- 3115
Query: 127 FAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186
SAP + P + V+ G C+ TG
Sbjct: 3116 ------------------SAPVFQVEPQ--------------DMTVRSGDDVALRCQATG 3143
Query: 187 RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
P P + WL+ PL+ S R+ L + V D G Y C+ N G A+ A
Sbjct: 3144 EPTPTIEWLQAGQPLRASRRLRTLPDGS---LWLENVETGDAGTYDCVAHNLLGSATARA 3200
Query: 247 ELSIQG 252
L ++G
Sbjct: 3201 FLVVRG 3206
Score = 68.2 bits (165), Expect = 7e-11
Identities = 57/238 (23%), Positives = 91/238 (38%), Gaps = 52/238 (21%)
Query: 16 SLSVDPSRVDSM-PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
S+ V P + + PLT A + P L + G P P + W R +P++
Sbjct: 1154 SVLVPPELIGDLDPLTNITAALHSPLTLLCE----------AMGIPPPAIRWFRGEEPVS 1203
Query: 75 SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLG 132
G L + G + L + E+D G Y+C A+N G R +VE+ V S +
Sbjct: 1204 PGEDTYL---LAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDL 1260
Query: 133 QPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192
+ V+ V +GQ C +TG PQP++
Sbjct: 1261 EEVIK----------------------------------VLDGQTAHLMCNVTGHPQPKL 1286
Query: 193 TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
TW K PL +S +L++ N G Y+C+ N G+ + +LS+
Sbjct: 1287 TWFKDGRPLARGDAHHISPDG--VLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 1342
Score = 67.4 bits (163), Expect = 1e-10
Identities = 58/214 (27%), Positives = 85/214 (39%), Gaps = 46/214 (21%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG----RFLLDCGIRGTFSLVIHAVHEE 99
+ EG + + G P P V W ++G P+ RF LD G SLV+ +
Sbjct: 2038 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-----SLVLKGLRAS 2092
Query: 100 DRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
D G YTC A N +G AR TV + V P+I
Sbjct: 2093 DAGAYTCVAHNPAGEDARLHTVNVLVP----------------------------PTI-- 2122
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+ A G +V + G++ C + G P V+WLK +PL S R +
Sbjct: 2123 ---KQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSG--HT 2177
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
L I V D G++TC+ + +G A + L +Q
Sbjct: 2178 LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 2211
Score = 65.9 bits (159), Expect = 4e-10
Identities = 56/236 (23%), Positives = 89/236 (37%), Gaps = 36/236 (15%)
Query: 15 TSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
T+L+ + R ++ + P P N + E A+ E G P P V+W + QP++
Sbjct: 677 TNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVS 736
Query: 75 SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQP 134
S + R L I D G Y C A+N +G+ ++ L V
Sbjct: 737 SWMGVTVSVDGR---VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVN---------- 783
Query: 135 VVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
P + PS+ G P T + R +C TG P P + W
Sbjct: 784 ----------VPPRITLPPSLPG--PVLVNTPV-----------RLTCNATGAPSPTLMW 820
Query: 195 LKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
LK P+ P+ + G +VL + D G Y+C+ V+ G+ L +
Sbjct: 821 LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 876
Score = 63.2 bits (152), Expect = 2e-09
Identities = 50/197 (25%), Positives = 79/197 (40%), Gaps = 40/197 (20%)
Query: 59 YPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQ 116
+P P +TW ++G P + L + GT L I +ED G+YTC TN G +
Sbjct: 1377 FPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 1433
Query: 117 VTVELTVEGSFAKQ--LGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE 174
VE+ + S +K LG+ V + TK+ + E
Sbjct: 1434 YHVEVLIPPSISKDDPLGEVGVKEV------------------------KTKVNSTLTLE 1469
Query: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
C+ P P + W K P+ PS+R+ V + ++L+I D G Y C+
Sbjct: 1470 -------CESWAVPPPTIRWYKDGQPVTPSSRLQVLGEG--RLLQIQPTQVSDSGRYLCV 1520
Query: 235 VVNGSGKASMSAELSIQ 251
N +G+ + IQ
Sbjct: 1521 ATNVAGEDDQDFNVLIQ 1537
Score = 62.8 bits (151), Expect = 3e-09
Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 36/213 (16%)
Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
PP + + + A E G P P VTW R+GQP+ G L +G SL +
Sbjct: 1073 PPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV--GAELGLQLQNQGQ-SLHVERAQ 1129
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
G+Y+C A N +G + EL +V P + G
Sbjct: 1130 AAHTGRYSCVAENLAGRAERKFEL--------------------------SVLVPPELIG 1163
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+ P L + C+ G P P + W +G P+ P + G +
Sbjct: 1164 DLDP-----LTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLA--GGWM 1216
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
L++ + D G+Y+CL N +G+A + + +
Sbjct: 1217 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEV 1249
Score = 61.2 bits (147), Expect = 9e-09
Identities = 50/199 (25%), Positives = 80/199 (40%), Gaps = 34/199 (17%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+ +G TA V G+P+P++TW ++G+P+ G + G V+ A + G
Sbjct: 1266 VLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD--GVLLQVLQA-NLSSAGH 1322
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y+C A N G + +L+V L P + LG + E
Sbjct: 1323 YSCIAANAVGEKTKHFQLSV-------LLAPTI---LGGAEDSADEE------------- 1359
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
V V C+ P P +TW+K P + S + + G L+I
Sbjct: 1360 ------VTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNA 1411
Query: 224 NQDDVGVYTCLVVNGSGKA 242
++D G YTC+V N G+A
Sbjct: 1412 QKEDAGQYTCVVTNELGEA 1430
Score = 60.8 bits (146), Expect = 1e-08
Identities = 57/224 (25%), Positives = 80/224 (35%), Gaps = 44/224 (19%)
Query: 31 EAPAFILPPRNLCIKEGATAK---FEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
+AP I+ PR G E V P P++TWHR+G + RG
Sbjct: 2386 QAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFP--ERG 2443
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
F L + A+ D G Y+C A N +G+ V + + + P
Sbjct: 2444 RF-LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH--------------------TVP 2482
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SAR 206
+ + P V V Q C+ G P P V+W K VPL P S R
Sbjct: 2483 TIRSGPP--------------AVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPR 2528
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ + L I V D G Y CL N +G +L +
Sbjct: 2529 FEILPEGS---LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV 2569
Score = 57.4 bits (137), Expect = 1e-07
Identities = 64/279 (22%), Positives = 94/279 (33%), Gaps = 51/279 (18%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
+P K V +++LL C+ S P TI W G + T + G L
Sbjct: 2756 SPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQL---R 2812
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP----- 1211
I A PED G Y C+AKN AG A ++ V P EN + + LP
Sbjct: 2813 IAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARG 2872
Query: 1212 -------------PVLGTESDATVKK--------------------------KPAPKTPP 1232
PV G E T++ + +
Sbjct: 2873 SPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHL 2932
Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
+ P P D+ +R G+ + L G+ W + + E V + G
Sbjct: 2933 TILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGG 2988
Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
S L A +E G Y EN++G QA + V + P
Sbjct: 2989 STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 3027
Score = 56.2 bits (134), Expect = 3e-07
Identities = 53/195 (27%), Positives = 82/195 (42%), Gaps = 41/195 (21%)
Query: 56 VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
VRG P V+W ++G P+ R LL +L I V D G +TC A + +G
Sbjct: 2146 VRGSPPIHVSWLKDGLPLPLSQRTLLH---GSGHTLRISKVQLADAGIFTCVAASPAGV- 2201
Query: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
+ +F Q+ P P +E P +F VVV G
Sbjct: 2202 -------ADRNFTLQVQVP------------PVLE---------PVEFQND---VVVVRG 2230
Query: 176 QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
+ C+ G P P V+W+K PL +S S + G L++ V D G Y+C+
Sbjct: 2231 SLVELPCEARGVPLPLVSWMKDGEPL-----LSQSLEQGPS-LQLEAVGAGDSGTYSCVA 2284
Query: 236 VNGSGKASMSAELSI 250
V+ +G+A +L++
Sbjct: 2285 VSEAGEARRHFQLTV 2299
Score = 55.5 bits (132), Expect = 5e-07
Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 48/201 (23%)
Query: 57 RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQ 116
RG P P +TW ++G + + + + RG L + D G YTC+A+N GA +
Sbjct: 336 RGVPTPNITWFKDGALLPTSTKVVYT---RGGRQLQLGRAQSSDAGVYTCKASNAVGAAE 392
Query: 117 VTVEL------TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
L T+EG+ G+P V K + GR
Sbjct: 393 KATRLDVYVPPTIEGAG----GRPYVVKAVA--------------------------GRP 422
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
V E C G P P ++W +P+ S S E +G VL + + G+
Sbjct: 423 VALE-------CVARGHPSPTLSWHHEGLPVAESNE-SRLETDG-SVLRLESPGEASSGL 473
Query: 231 YTCLVVNGSGKASMSAELSIQ 251
Y+C+ + +G+A + + +Q
Sbjct: 474 YSCVASSPAGEAVLQYSVEVQ 494
Score = 54.7 bits (130), Expect = 8e-07
Identities = 61/259 (23%), Positives = 96/259 (37%), Gaps = 54/259 (20%)
Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQD----VHVAEGKKLLLQCQVSSDPPATIIWT 1132
C+ +A D + S PAF+Q + V V G K +L C+ + P T+ W
Sbjct: 1817 CEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 1876
Query: 1133 LNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
+G+ L + + G + I++A D+GLY C N AG+A + +TV P
Sbjct: 1877 KDGQPLVLAQRTQALRGGQ--RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPT 1934
Query: 1193 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1252
EN K TE+ + V AG
Sbjct: 1935 FENPK------------------TETVSQV----------------------------AG 1948
Query: 1253 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1312
+ L V+G T TW+K R ++ S V + G +L + + G YT +
Sbjct: 1949 SPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVS--RGGRLQLSRLQPAQAGTYTCVA 2006
Query: 1313 ENKLGSRQAQVNLTVVDKP 1331
EN + + V+ P
Sbjct: 2007 ENTQAEARKDFVVAVLVAP 2025
Score = 54.3 bits (129), Expect = 1e-06
Identities = 40/138 (28%), Positives = 61/138 (44%), Gaps = 13/138 (9%)
Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT----QHSLC 681
++GL D+ + G + G P P+V W + SE H Q G + SL
Sbjct: 7 IKGLGDVALTVGLEAG-GCGTHGTPKPQVTWRKGPS----SEPLH-GQPGVAVLEEGSLF 60
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
+ V P D+G Y C+A N G +A L V P + + +V+ GQS+ +
Sbjct: 61 LASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIRED---GRKANVSGMAGQSLTLE 117
Query: 742 CAIAGDPFPTVHWLRDGK 759
C G P P + WL+D +
Sbjct: 118 CDANGFPVPEIVWLKDAQ 135
Score = 53.9 bits (128), Expect = 1e-06
Identities = 60/255 (23%), Positives = 92/255 (36%), Gaps = 54/255 (21%)
Query: 2 GDVKLVASSHISKTSLSVD-----PSRVDSMPLTEAPAFI-LPPRNLCIKEGATAKFEGR 55
G + VAS+ T L P R+ P P + P R C GA
Sbjct: 761 GSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGA------- 813
Query: 56 VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
P P + W ++G P++ G L G L + + D G+Y+C A + G
Sbjct: 814 ----PSPTLMWLKDGNPVSPAGTPGLQV-FPGGRVLTLASARASDSGRYSCVAVSAVGED 868
Query: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
+ V L V PSI GE +L VV
Sbjct: 869 RQDVVLQVH--------------------------MPPSILGE-------ELNVSVVANE 895
Query: 176 QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
+ C+ P P ++W K PL+P V +S + L++ + D G YTC
Sbjct: 896 SVA-LECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEA 952
Query: 236 VNGSGKASMSAELSI 250
+N +G++ L++
Sbjct: 953 LNQAGRSEKHYNLNV 967
Score = 53.9 bits (128), Expect = 1e-06
Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 8/119 (6%)
Query: 1721 SSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 1780
+ G+ T + E+ +D A L A P ++ S R+ V+EG R DC+
Sbjct: 1997 AQAGTYTCVAENTQAEARKDFVVAVLVA-----PRIRS--SGVAREHHVLEGQEVRLDCE 2049
Query: 1781 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
+G P P+V W KD + + + + DG SL++ + D YTC A N GE
Sbjct: 2050 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-SLVLKGLRASDAGAYTCVAHNPAGE 2107
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
+AP F+ + QD+ V G + L+CQ + +P TI W G+ L+ ++ + +GSL
Sbjct: 3116 SAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLE 3175
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
++E D G Y CVA N G A + V P
Sbjct: 3176 NVETG---DAGTYDCVAHNLLGSATARAFLVVRGEP 3208
Score = 53.5 bits (127), Expect = 2e-06
Identities = 67/282 (23%), Positives = 101/282 (35%), Gaps = 62/282 (21%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L V G+ L L CQ S P TI W NG+ + + ++ +G+ ++ I+ +
Sbjct: 505 LGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT--TLHIDHVELD 562
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD--------DAPASENTKAPEMKSRRPKSSLPP--- 1212
GL+ C A N+AG A +V+V + P + E S P + PP
Sbjct: 563 HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 622
Query: 1213 ----------VLGTESDATVKKKP-----APKTPP------------------------- 1232
V G S ++ +P A PP
Sbjct: 623 GWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGE 682
Query: 1233 -------KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
K +PP I P ++ V SV L +G P +W K + + S M
Sbjct: 683 SKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMG 740
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
V S +G L I A+ G Y + N GS + + L V
Sbjct: 741 VTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRV 782
Score = 53.5 bits (127), Expect = 2e-06
Identities = 65/285 (22%), Positives = 107/285 (37%), Gaps = 53/285 (18%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V V + L+C + PP T+ W +G+ + + L +G S+ +E+A G
Sbjct: 1077 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQ--SLHVERAQAAHTG 1134
Query: 1167 LYKCVAKNDAGQAECSCQVTV--------DDAPASENTKA----------------PEMK 1202
Y CVA+N AG+AE +++V D P + T A P ++
Sbjct: 1135 RYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 1194
Query: 1203 SRRPKSSLPPVLGT---------------ESDATVKKKPAPKTPPKA--------AMPPQ 1239
R + + P T E D+ + A +A +PP
Sbjct: 1195 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 1254
Query: 1240 I--IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1297
I E KV G++ L VTG TW K + + + + S +G L +
Sbjct: 1255 IENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHI--SPDGVLLQV 1312
Query: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
L A G Y+ + N +G + L+V+ P G ++D
Sbjct: 1313 LQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 1357
Score = 52.4 bits (124), Expect = 4e-06
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
V P + DL EGS A CK G P+P + W KD Q + + + + +
Sbjct: 2845 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGA---EGKFTIQPSGE 2901
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L++ ++ G D YTC A N++G A L +
Sbjct: 2902 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 2934
Score = 51.2 bits (121), Expect = 9e-06
Identities = 55/233 (23%), Positives = 89/233 (38%), Gaps = 41/233 (17%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
+++V L L+C+ + PP TI W +G+ + + + + EG L + I+
Sbjct: 1455 VKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL--LQIQPTQVS 1512
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP----ASENTKAPEMKSRRPKSSLPPVLGTESD 1219
D G Y CVA N AG+ + V + P + + A E+ SR ++ TE
Sbjct: 1513 DSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGV---TEYR 1569
Query: 1220 ATVKKKPA-PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
V+ PA A PP + + EDQ + AG+ V +
Sbjct: 1570 EIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVL-------------------- 1609
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ G L I R E+ G Y+ N++G L V+ P
Sbjct: 1610 -----------QGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPP 1651
Score = 50.1 bits (118), Expect = 2e-05
Identities = 59/256 (23%), Positives = 96/256 (37%), Gaps = 56/256 (21%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ V +G+ L C V+ P + W +G+ L +S +G L V +A G
Sbjct: 1264 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVL--QANLSSAG 1321
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y C+A N G+ Q++V AP +LG D+
Sbjct: 1322 HYSCIAANAVGEKTKHFQLSVLLAPT--------------------ILGGAEDSA----- 1356
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
E+ V + L + TWMK + S ++++
Sbjct: 1357 -----------------DEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQL 1399
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP----DPPAGTPCASD 1342
+G L IL A++E G YT +V N+LG ++ V+ P D P G +
Sbjct: 1400 LPGTHG--LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKE 1457
Query: 1343 IR---SSSLTL---SW 1352
++ +S+LTL SW
Sbjct: 1458 VKTKVNSTLTLECESW 1473
Score = 49.7 bits (117), Expect = 3e-05
Identities = 43/208 (20%), Positives = 71/208 (34%), Gaps = 40/208 (19%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+ +T + G P P ++W +NG P + R + + L + D
Sbjct: 1666 VNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQV---LEDGQVLQVSTAEVADAAS 1722
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C A N +G+ + L V + PP+
Sbjct: 1723 YMCVAENQAGSAEKLFTLRV----------------------------------QVPPRI 1748
Query: 164 A-TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
A L +V C + P P+VTW K + L V + G L++
Sbjct: 1749 AGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLP--GTHTLQLGR 1806
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSI 250
D G+YTC +N +G+ +LS+
Sbjct: 1807 ARLSDSGMYTCEALNAAGRDQKLVQLSV 1834
Score = 49.7 bits (117), Expect = 3e-05
Identities = 52/234 (22%), Positives = 83/234 (35%), Gaps = 69/234 (29%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + L C V DP I W +G L+ + Q GSL +I + +D G Y+C+
Sbjct: 3042 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSL---TIHRTERDDAGRYQCL 3098
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A+N+ G A+ + + AP +
Sbjct: 3099 AENEMGVAKKVVILVLQSAPVFQVE----------------------------------- 3123
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK------ 1285
P+D VR+G+ V L + TG T W++ + ++ S ++
Sbjct: 3124 ------------PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS 3171
Query: 1286 --VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
+EN E G G Y + N LGS A+ L V +P G+
Sbjct: 3172 LWLENVETGD-----------AGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS 3214
Score = 48.9 bits (115), Expect = 5e-05
Identities = 47/219 (21%), Positives = 77/219 (35%), Gaps = 48/219 (21%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V E + L+C S PP + W + + + + +S +G + + IE+A D G Y
Sbjct: 706 VLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRV--LRIEQAQLSDAGSY 763
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
+CVA N AG E + V+
Sbjct: 764 RCVASNVAGSTELRYGLRVN---------------------------------------- 783
Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
PP+ +PP + V V L TG T W+K + + ++
Sbjct: 784 -VPPRITLPPSL-----PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQV 837
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
G LT+ +AR G Y+ + + +G + V L V
Sbjct: 838 FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 876
Score = 48.5 bits (114), Expect = 6e-05
Identities = 49/220 (22%), Positives = 83/220 (37%), Gaps = 53/220 (24%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G+ + + C V PP + W +G L ++ +L GS ++ I K D G++ CV
Sbjct: 2137 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL--HGSGHTLRISKVQLADAGIFTCV 2194
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A + AG A+ + + V +PPVL
Sbjct: 2195 AASPAGVADRNFTLQV---------------------QVPPVL----------------- 2216
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
+ ++F D V G VEL + G +WMK + E + ++ E
Sbjct: 2217 -------EPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMK------DGEPLLSQSLEQ 2263
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
G L + A G Y+ + ++ G + LTV++ P
Sbjct: 2264 GPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPP 2303
Score = 47.0 bits (110), Expect = 2e-04
Identities = 60/228 (26%), Positives = 89/228 (39%), Gaps = 21/228 (9%)
Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAE---------TLKPMGNAKPDEN 1058
V P + P GP VG A L+ A+PA L+ + + E
Sbjct: 2383 VRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPER 2442
Query: 1059 LKSASKEELKKDVKNDVNCK-RGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLL 1117
+ + L D +C R AG+T R E T P + V+V+ + LL
Sbjct: 2443 GRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-TVPTIRSGPPAVNVSVNQTALL 2501
Query: 1118 QCQVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
CQ P + W + L ++ +F IL EGSL I+ L +D G Y C+A N
Sbjct: 2502 PCQADGVPAPLVSWRKDRVPLDPRSPRFEILP-EGSL---RIQPVLAQDAGHYLCLASNS 2557
Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
AG + V + PA AP + + P +L E+ + K
Sbjct: 2558 AGSDRQGRDLRVLEPPAI----APSPSNLTLTAHTPALLPCEASGSPK 2601
Score = 47.0 bits (110), Expect = 2e-04
Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F +D+ V G C+ G P P + W + Q +R SR + D SL
Sbjct: 3118 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG----SLW 3173
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 1854
+ +V D Y C A N LG AT A L+V +G
Sbjct: 3174 LENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQG 3210
Score = 46.2 bits (108), Expect = 3e-04
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 1768 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
E+VE + A C P P++ W+++DQ + + G L I V ++
Sbjct: 1570 EIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSV---LQGGRVLQIPLVRAENAG 1626
Query: 1828 KYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
+Y+CKA N +GE EL+V T G+ EE
Sbjct: 1627 RYSCKASNEVGEDWLHYELLVLTPPVILGDTEE 1659
Score = 44.3 bits (103), Expect = 0.001
Identities = 60/271 (22%), Positives = 108/271 (39%), Gaps = 53/271 (19%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
+V V E + L C+ P I W +G L T+ ++ ++ G + + +A D
Sbjct: 320 EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGR--QLQLGRAQSSDA 377
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENT--------------KAPEMKSR-RPKSSL 1210
G+Y C A N G AE + ++ V P E A E +R P +L
Sbjct: 378 GVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTL 437
Query: 1211 P------PVLGT-----ESDATVKKKPAP------------KTPPKAA---------MPP 1238
PV + E+D +V + +P +P A +PP
Sbjct: 438 SWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPP 497
Query: 1239 QIIQFPEDQKVR--AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
Q++ +V G+ +EL + +G+ T W++ + +E ++V + G+ L
Sbjct: 498 QLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQV--ASQGTTLH 555
Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
I +H G + N+ G+ A+V ++V
Sbjct: 556 IDHVELDHSGLFACQATNEAGTAGAEVEVSV 586
Score = 44.3 bits (103), Expect = 0.001
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
DV V G + L C+ P + W +G+ L + ++G S+ +E D
Sbjct: 2224 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL----EQGP--SLQLEAVGAGDS 2277
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
G Y CVA ++AG+A Q+TV + P E++ P S P
Sbjct: 2278 GTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTP 2318
Score = 43.5 bits (101), Expect = 0.002
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
++ V+E + C+ G P P + WFKD + S ++ Y G L + D
Sbjct: 320 EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTST--KVVYTRGGR-QLQLGRAQSSD 376
Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1858
YTCKA N++G A L V EG G
Sbjct: 377 AGVYTCKASNAVGAAEKATRLDVYVPPTIEGAG 409
Score = 43.5 bits (101), Expect = 0.002
Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
+V V + + L+CQ + PP + W +G+ L+ + LS + +L + +++A D
Sbjct: 888 NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDA 945
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAP 1191
G Y C A N AG++E + V AP
Sbjct: 946 GHYTCEALNQAGRSEKHYNLNVWVAP 971
Score = 43.5 bits (101), Expect = 0.002
Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
++V++G A C + G+P P++ WFKD + + I D L +
Sbjct: 1264 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD---GVLLQVLQANLSSA 1320
Query: 1827 AKYTCKAVNSLGEAT---CTAELIVETMEEGEGEGEEEE 1862
Y+C A N++GE T + L+ T+ G + +EE
Sbjct: 1321 GHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE 1359
Score = 43.1 bits (100), Expect = 0.003
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Query: 1101 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKA 1160
++ +++V V + LQC +P TI W NG + + + ++G + VS +
Sbjct: 1658 EELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 1717
Query: 1161 LPEDRGLYKCVAKNDAGQAE 1180
D Y CVA+N AG AE
Sbjct: 1718 --ADAASYMCVAENQAGSAE 1735
Score = 42.7 bits (99), Expect = 0.003
Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 7/97 (7%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
D+ VV GS C+ G P P V W KD + + + + SL + V D
Sbjct: 2224 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL-------LSQSLEQGPSLQLEAVGAGD 2276
Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
Y+C AV+ GEA +L V E G+ E
Sbjct: 2277 SGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTE 2313
Score = 42.0 bits (97), Expect = 0.006
Identities = 77/363 (21%), Positives = 129/363 (35%), Gaps = 71/363 (19%)
Query: 987 GKKKLPAENGSSSAETLNA-----KAVESS---KPLSNAQPSGPLKPV-GNAKPAETLKP 1037
G+ +L +++G + E LNA K V+ S P P GP V L
Sbjct: 1805 GRARL-SDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSC 1863
Query: 1038 MGNAKPAETL------KPMGNAKPDENLKSASKEELKKDVKND---VNCKRGHAGTTDNE 1088
+A P T+ +P+ A+ + L+ + E+++ +D +CK +
Sbjct: 1864 ETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR 1923
Query: 1089 KRSESQGTAPAFKQ-KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI-IL 1146
+ + P F+ K + V G L+L C VS P T+ W + ++++ ++
Sbjct: 1924 TFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVV 1983
Query: 1147 SQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
S+ G L + + P G Y CVA+N +A V V AP R
Sbjct: 1984 SRGGRL---QLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP-------------RI 2027
Query: 1207 KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQP 1266
+SS + V G+ V L + G P
Sbjct: 2028 RSS--------------------------------GVAREHHVLEGQEVRLDCEADGQPP 2055
Query: 1267 ITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVN 1324
W+K + + + +G L + R G YT + N G +R VN
Sbjct: 2056 PDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVN 2115
Query: 1325 LTV 1327
+ V
Sbjct: 2116 VLV 2118
Score = 42.0 bits (97), Expect = 0.006
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRES--RHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
G + + DC + G P P++ W KD +R S RH + N SL I DD +Y
Sbjct: 3042 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRH------QLQNGSLTIHRTERDDAGRY 3095
Query: 1830 TCKAVNSLGEATCTAELIVET 1850
C A N +G A L++++
Sbjct: 3096 QCLAENEMGVAKKVVILVLQS 3116
Score = 41.6 bits (96), Expect = 0.007
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
C+ +P P + W KD SR+ Q+ G L I + +D +YTC N LG
Sbjct: 1372 CEALAFPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELG 1428
Query: 1839 EA 1840
EA
Sbjct: 1429 EA 1430
Score = 41.6 bits (96), Expect = 0.007
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
G A C+ + P+P V W+KD Q + ++ Q G L I + D Y+C
Sbjct: 1856 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQA---LRGGQRLEIQEAQVSDKGLYSC 1912
Query: 1832 KAVNSLGEATCTAELIVE 1849
K N GEA T L V+
Sbjct: 1913 KVSNVAGEAVRTFTLTVQ 1930
Score = 40.8 bits (94), Expect = 0.012
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 1766 DLEVVEG---SAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
DLE V S+ C + +P+PEV W+KD Q++ + G +L +
Sbjct: 1752 DLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV---FLLPGTHTLQLGRAR 1808
Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
D YTC+A+N+ G +L V
Sbjct: 1809 LSDSGMYTCEALNAAGRDQKLVQLSV 1834
Score = 40.4 bits (93), Expect = 0.016
Identities = 46/243 (18%), Positives = 84/243 (34%), Gaps = 53/243 (21%)
Query: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
+ E++G +++ + E L C ++ PP + W + L + + Q
Sbjct: 1557 REEEARGGVTEYRE------IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 1610
Query: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208
G + + + +A E+ G Y C A N+ G+ ++ V
Sbjct: 1611 GGRVLQIPLVRA--ENAGRYSCKASNEVGEDWLHYELLV--------------------- 1647
Query: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1268
PPV+ +++ V E+ V A +V L G T
Sbjct: 1648 LTPPVILGDTEELV----------------------EEVTVNASSTVSLQCPALGNPVPT 1685
Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
+W++ S ++V E+G L + A Y + EN+ GS + L V
Sbjct: 1686 ISWLQNGLPFSPSPRLQV--LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQ 1743
Query: 1329 DKP 1331
P
Sbjct: 1744 VPP 1746
Score = 40.0 bits (92), Expect = 0.021
Identities = 26/71 (36%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 182 CKITGRPQPQVTWLKG--NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
C G P+PQVTW KG + PL V+V E+ L + V+ D G Y C N
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGS---LFLASVSPADSGDYECQATNEV 80
Query: 240 GKASMSAELSI 250
G S A+L +
Sbjct: 81 GSTSRRAKLVV 91
Score = 39.3 bits (90), Expect = 0.036
Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 10/120 (8%)
Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1136
C ++ +D + R PA ++ + LL C+ S P ++W +G+
Sbjct: 2552 CLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQ 2611
Query: 1137 TLKTTKFIILSQEGSLCSVSIEKAL-----PEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
L Q+G+ + L P+D ++CV N+ G+A QVTV P
Sbjct: 2612 KLD-----FRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPP 2666
Score = 39.3 bits (90), Expect = 0.036
Identities = 65/278 (23%), Positives = 93/278 (33%), Gaps = 49/278 (17%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSVS 1156
P D V ++L C + P T+ W+ G L +S G+L
Sbjct: 2666 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL---E 2722
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP------------ASENTKAPEMKSR 1204
I +ALP G Y C A+N AG A +TV +P A E P S
Sbjct: 2723 IGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASG 2782
Query: 1205 RP-------KSSLPPVLGTESDA--------------------TVKKKPA----PKTPPK 1233
P K L G + + K A KT
Sbjct: 2783 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLV 2842
Query: 1234 AAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
+PP I D G L K G+ TW K + + +E K +G
Sbjct: 2843 VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEG-KFTIQPSG- 2900
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+L + + G YT EN +G + +V+LT++ P
Sbjct: 2901 ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLP 2938
Score = 38.5 bits (88), Expect = 0.062
Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 15/157 (9%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
++V V + L C+ + P I W +G + ++ I L + I A ED
Sbjct: 1358 EEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNAQKED 1415
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPA-SENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
G Y CV N+ G+A + V V P+ S++ E+ + K+ + L E ++
Sbjct: 1416 AGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESW-- 1473
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
A PP I + + Q V +++ G+
Sbjct: 1474 ----------AVPPPTIRWYKDGQPVTPSSRLQVLGE 1500
Score = 38.1 bits (87), Expect = 0.081
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQ--IDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 1836
C G P P+V W K S E H Q + E+G SL ++ V D Y C+A N
Sbjct: 24 CGTHGTPKPQVTWRKGPSS--EPLHGQPGVAVLEEG--SLFLASVSPADSGDYECQATNE 79
Query: 1837 LGEATCTAELIV 1848
+G + A+L+V
Sbjct: 80 VGSTSRRAKLVV 91
Score = 37.7 bits (86), Expect = 0.11
Identities = 52/250 (20%), Positives = 85/250 (34%), Gaps = 45/250 (18%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
GD A + TS++ RV+ + P P + + TA + G P
Sbjct: 2457 GDYSCTARNAAGSTSVAF---RVE---IHTVPTIRSGPPAVNVSVNQTALLPCQADGVPA 2510
Query: 62 PQVTWHRNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P V+W ++ P+ RF I SL I V +D G Y C A+N +G+ + +
Sbjct: 2511 PLVSWRKDRVPLDPRSPRF----EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD 2566
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
L V PA+ PS + +
Sbjct: 2567 LRV--------------------LEPPAIAPSPS--------------NLTLTAHTPALL 2592
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
C+ +G P+P V W K L + L + D + C+V N G
Sbjct: 2593 PCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVG 2652
Query: 241 KASMSAELSI 250
+A ++++
Sbjct: 2653 EAHRLYQVTV 2662
Score = 37.7 bits (86), Expect = 0.11
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P + + +L + + A C+ G P P VVW+KD Q + + R Q Y + +L+
Sbjct: 2573 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL-DFRLQQGAYRLLPSNALL 2631
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEA 1840
++ D A++ C N +GEA
Sbjct: 2632 LTAPGPQDSAQFECVVSNEVGEA 2654
Score = 37.7 bits (86), Expect = 0.11
Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 13/132 (9%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F D + G +L L+C P I WT+N + + +S++ ++
Sbjct: 2938 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQR 2993
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT- 1216
ED G Y C A+N G+ + V V +AP + + + PV G+
Sbjct: 2994 AAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYL--------VEPVGGSI 3045
Query: 1217 ESDATVKKKPAP 1228
+ D V+ P P
Sbjct: 3046 QLDCVVRGDPVP 3057
Score = 37.4 bits (85), Expect = 0.14
Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 48/146 (32%)
Query: 58 GYPEPQVTWHR-------NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
G P+PQVTW + +GQP G +L+ G SL + +V D G Y C+ATN
Sbjct: 28 GTPKPQVTWRKGPSSEPLHGQP----GVAVLEEG-----SLFLASVSPADSGDYECQATN 78
Query: 111 GSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
G+ +L V + P++ + + V
Sbjct: 79 EVGSTSRRAKLVV--------------------YVPPSI------------REDGRKANV 106
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLK 196
GQ C G P P++ WLK
Sbjct: 107 SGMAGQSLTLECDANGFPVPEIVWLK 132
Score = 37.0 bits (84), Expect = 0.18
Identities = 35/149 (23%), Positives = 56/149 (37%), Gaps = 8/149 (5%)
Query: 1694 WQKTG---NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVA 1750
W K G A R I L + L+ +K G T + E E+ ++ L +
Sbjct: 1384 WMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPS 1443
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
K P +++++ S +C+ P P + W+KD Q + S Q+ +
Sbjct: 1444 ISKDD--PLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGE- 1500
Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
L I D +Y C A N GE
Sbjct: 1501 --GRLLQIQPTQVSDSGRYLCVATNVAGE 1527
Score = 37.0 bits (84), Expect = 0.18
Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 8/105 (7%)
Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
W K G L S ++ G S + + G+ S + SE ++ + E
Sbjct: 2249 WMKDGEP------LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEP 2302
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1798
PH++ T +L + G+ C +G P P + W KD Q++
Sbjct: 2303 PHIEDSGQPT--ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL 2345
Score = 36.6 bits (83), Expect = 0.23
Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 4/92 (4%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRE-SRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
G+ C G P P+V W KD Q + H Q+ EDG I G D+ +Y
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQV--QEDGQVLRITGSHVG-DEGRYQ 288
Query: 1831 CKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
C A + G+ +L V G E E
Sbjct: 289 CVAFSPAGQQARDFQLRVHAPPTIWGSNETGE 320
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
+ VV+ A +C G P P V W +D Q + Q+ ++ SL +
Sbjct: 1077 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQL---QNQGQSLHVERAQAAHT 1133
Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
+Y+C A N G A EL V
Sbjct: 1134 GRYSCVAENLAGRAERKFELSV 1155
Score = 36.6 bits (83), Expect = 0.23
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 3/74 (4%)
Query: 1778 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1837
+C +E P P++ W +D ++E H Q + E G L + + D Y+C A N+
Sbjct: 2411 ECSVEAEPAPKITWHRDGIVLQEDAHTQ--FPERGR-FLQLQALSTADSGDYSCTARNAA 2467
Query: 1838 GEATCTAELIVETM 1851
G + + + T+
Sbjct: 2468 GSTSVAFRVEIHTV 2481
Score = 36.6 bits (83), Expect = 0.23
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
V P F+ D + G C G P P + W +D+ + E ++DG +
Sbjct: 2936 VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS-----EQDGGST 2990
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
L + V +D Y C A N +G + + V+ +GE
Sbjct: 2991 LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 3032
Score = 36.2 bits (82), Expect = 0.31
Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
V+ + R C G P P ++W KD + + + G L ++ D +
Sbjct: 798 VLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-LTLASARASDSGR 856
Query: 1829 YTCKAVNSLGE 1839
Y+C AV+++GE
Sbjct: 857 YSCVAVSAVGE 867
Score = 35.8 bits (81), Expect = 0.40
Identities = 32/153 (20%), Positives = 55/153 (35%), Gaps = 19/153 (12%)
Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
W K GN V +G G + G L + + S + AV E++
Sbjct: 820 WLKDGNPVSP----------AGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDR 869
Query: 1754 P------HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
H+ P ++ VV + +C+ P P + W+KD + + +
Sbjct: 870 QDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLS 929
Query: 1808 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
D+ L + D YTC+A+N G +
Sbjct: 930 ADK---ALLQVDRADVWDAGHYTCEALNQAGRS 959
Score = 35.8 bits (81), Expect = 0.40
Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 5/100 (5%)
Query: 1236 MPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
+PPQI + P V L TG P T TW + + + ++++N G
Sbjct: 1063 VPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQ--G 1120
Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
L + A+ H G Y+ + EN G + + L+V+ P+
Sbjct: 1121 QSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPE 1160
Score = 35.4 bits (80), Expect = 0.52
Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 15/124 (12%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
++ + G + L C P I W +G+ L T+ S+ + V D
Sbjct: 2313 ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL--TRLENNSRATRVLRV-------RDA 2363
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
GLY C+A++ AG E S +V V P + P L VL + +V+ +
Sbjct: 2364 GLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL--VL----ECSVEAE 2417
Query: 1226 PAPK 1229
PAPK
Sbjct: 2418 PAPK 2421
Score = 34.7 bits (78), Expect = 0.89
Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 3/70 (4%)
Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
V+E ++ +C G P P+V WFK Q + S + DG L I D
Sbjct: 706 VLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMGVTVSVDGRV-LRIEQAQLSDAGS 762
Query: 1829 YTCKAVNSLG 1838
Y C A N G
Sbjct: 763 YRCVASNVAG 772
Score = 34.3 bits (77), Expect = 1.2
Identities = 59/265 (22%), Positives = 90/265 (33%), Gaps = 65/265 (24%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPE 1163
Q+V G + LQC S P + WT + + L + + ++G + ++
Sbjct: 225 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV--G 282
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y+CVA + AGQ Q+ V AP P + G+ V
Sbjct: 283 DEGRYQCVAFSPAGQQARDFQLRV-HAP-------------------PTIWGSNETGEV- 321
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
A M ++Q L + G TW K + S
Sbjct: 322 ----------AVMEDHLVQ--------------LLCEARGVPTPNITWFKDGALLPTS-- 355
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP------------ 1331
KV + G +L + A+ G YT N +G+ + L V P
Sbjct: 356 TKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVV 415
Query: 1332 DPPAGTPCASDIRS---SSLTLSWY 1353
AG P A + + S TLSW+
Sbjct: 416 KAVAGRPVALECVARGHPSPTLSWH 440
Score = 33.1 bits (74), Expect = 2.6
Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
C+ G P P + WF+ ++ + + Y G L ++ D Y+C A N G
Sbjct: 1183 CEAMGIPPPAIRWFRGEEPVSPG---EDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 1239
Query: 1839 EATCTAELIVETMEEGEGEGEEEEE 1863
EA VE + E E+ EE
Sbjct: 1240 EA--RRNFSVEVLVPPSIENEDLEE 1262
Score = 32.3 bits (72), Expect = 4.4
Identities = 11/27 (40%), Positives = 16/27 (59%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSI 1798
G + +C G+P PE+VW KD Q +
Sbjct: 111 GQSLTLECDANGFPVPEIVWLKDAQLV 137
Score = 32.0 bits (71), Expect = 5.8
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 3/84 (3%)
Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
H P + V A C+ +G P P V W KD + + R + + +G
Sbjct: 2479 HTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPL-DPRSPRFEILPEG-- 2535
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
SL I V D Y C A NS G
Sbjct: 2536 SLRIQPVLAQDAGHYLCLASNSAG 2559
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 12/101 (11%)
Query: 1751 EEKPHVKPYFS--KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY 1808
+ P VKP S + + + EV+ C+ G P P + W K+ ++ Q+
Sbjct: 2754 QASPVVKPLPSVVRAVAEEEVL------LPCEASGIPRPTITWQKEGLNVATGVSTQVL- 2806
Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L I+ +D Y C A NS G A L+V+
Sbjct: 2807 ---PGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 2844
Score = 31.6 bits (70), Expect = 7.6
Identities = 27/130 (20%), Positives = 49/130 (37%), Gaps = 5/130 (3%)
Query: 1719 RKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFD 1778
R S G +S L + + +A L+ E + + ++ + + + G
Sbjct: 462 RLESPGEASSGLYS--CVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELP 519
Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
C+ G P P + W ++ + E Q+ +L I V D + C+A N G
Sbjct: 520 CQASGSPVPTIQWLQNGRPAEELAGVQV---ASQGTTLHIDHVELDHSGLFACQATNEAG 576
Query: 1839 EATCTAELIV 1848
A E+ V
Sbjct: 577 TAGAEVEVSV 586
Score = 31.6 bits (70), Expect = 7.6
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 3/71 (4%)
Query: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
V GS C + G P P V W KD + S + G L +S + Y
Sbjct: 1946 VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGV-VSRGGR--LQLSRLQPAQAGTY 2002
Query: 1830 TCKAVNSLGEA 1840
TC A N+ EA
Sbjct: 2003 TCVAENTQAEA 2013
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-D 1825
++ V G +C G+P P + W + + ES +++ D S++ + G+
Sbjct: 415 VKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDG----SVLRLESPGEAS 470
Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEE---GEGEGE 1859
Y+C A + GEA + V+ + EG G+
Sbjct: 471 SGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQ 507
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 1/93 (1%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
L V EG C+ G P P++ W KD Q + + + L + +
Sbjct: 981 LTVREGHPTSLSCECRGVPFPKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQE 1039
Query: 1827 AKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1859
YTC+ N +G ++ +L V + G E
Sbjct: 1040 GTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 1072
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 171 bits (434), Expect = 5e-42
Identities = 181/790 (22%), Positives = 294/790 (37%), Gaps = 114/790 (14%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
P L + GA + +G P+P +TWH++GQ +T L+ R T L +
Sbjct: 3502 PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR-----LENNSRATRVLRVR---- 3552
Query: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
D G YTC A + +GA + K+ R AP P+I G
Sbjct: 3553 -DAGLYTCLAESPAGA---------------------IEKSFRVRVQAP-----PNIVGP 3585
Query: 159 CPPKFATKL--GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
P+F L G++V++ C + P P++TW + + LQ A E+ +
Sbjct: 3586 RGPRFVVGLAPGQLVLE--------CSVEAEPAPKITWHRDGIVLQEDAHTQFPERG--R 3635
Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD-----------SANRSFVRETK 265
L++ ++ D G Y+C N +G S++ + I + S N++ + +
Sbjct: 3636 FLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQ 3695
Query: 266 ATNSDV-----RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
A RK+ + + + + L + Q G A++ R+
Sbjct: 3696 ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQG 3755
Query: 321 KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPR--------APGLGVLSPSGEERK 372
+ + P AP L T+ + L P+ L G R
Sbjct: 3756 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 3815
Query: 373 RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVK 432
P+ T P Q + VVS + P V V
Sbjct: 3816 LPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVV 3875
Query: 433 FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNA 492
C +GIP P V+W G + + Y + S L + +A +G Y+C+A N+
Sbjct: 3876 LTCHSTGIPAPTVSWSKAGAQLGARGSG---YRVSPSGALEIGQALPIHAGRYTCSARNS 3932
Query: 493 QGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
G L V+ V++ PS + + ++ +L C G P P ITW G
Sbjct: 3933 AGVAHKHVFLTVQASPVVKPLPSVVRAVAE------EEVLLPCEASGIPRPTITWQKEGL 3986
Query: 553 PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL 612
+ ST +L I A PED G Y C+A+N+ G + V
Sbjct: 3987 NVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ----------- 4035
Query: 613 LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE-DFHF 671
P+ GL DL +GS + + G+P P + W +G + +E F
Sbjct: 4036 --------VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTI 4087
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 731
+ G L ++ + +D GTYTC A N+ G R + LT+ P F + P +
Sbjct: 4088 QPSG---ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL-----VLPVFTTLPGDRS 4139
Query: 732 ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 791
LG + + CA G P P + W + + + + V + + TL V +G
Sbjct: 4140 LRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSEQDGGSTLQRAAVSREDSGT 4194
Query: 792 YEILLKNRVG 801
Y +NRVG
Sbjct: 4195 YVCWAENRVG 4204
Score = 169 bits (429), Expect = 2e-41
Identities = 197/775 (25%), Positives = 290/775 (37%), Gaps = 145/775 (18%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
K +T E P P + W+++GQP+T R + + L I D G+Y
Sbjct: 2652 KVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQV---LGEGRLLQIQPTQVSDSGRY 2708
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
C ATN +G + ++ P + + +GD +A + +R E
Sbjct: 2709 LCVATNVAGEDDQDFNVLIQ--------VPPMFQKVGDFSAAFEILSRE----EEARGGV 2756
Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
T+ +V E C P P +TW + + PL VSV + G +VL+I V
Sbjct: 2757 TEYREIV--ENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ--GGRVLQIPLVR 2812
Query: 225 QDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESK 284
++ G Y+C N G+ + EL V D + V V S
Sbjct: 2813 AENAGRYSCKASNEVGEDWLHYEL-----------LVLTPPVILGDTEELVEEVTVNASS 2861
Query: 285 LDSLEAAAKSKNCSSPQRGGSPP---WAANSQPQPPRESKLESCKDSPRTAPQTPVLQKT 341
SL+ P G P W N P P +P LQ
Sbjct: 2862 TVSLQC---------PALGNPVPTISWLQNGLPFSP-----------------SPRLQVL 2895
Query: 342 SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR 401
LQ + + A + V ++ R P R GL + V +
Sbjct: 2896 EDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLR-VQVPPRIAGLDLEQVTAIL--- 2951
Query: 402 RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI 461
N +V C+V P PEV W+ + + E
Sbjct: 2952 --------------------------NSSVSLPCDVHAHPNPEVTWYKDSQALSLGE--- 2982
Query: 462 EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLK 521
EV+ G+H L L +AR DSG Y+C A NA G+ ++ +L+V+ V P+F +
Sbjct: 2983 EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGR-----DQKLVQLSVL-VPPAFRQAPR 3036
Query: 522 ---DCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPE 576
D ++ G VL C P P +TW +GQP+ A R+ G L IQ+A
Sbjct: 3037 GPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS 3096
Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
D G Y+C N G+ + +TV +P P Q +
Sbjct: 3097 DKGLYSCKVSNVAGEAVRTFTLTVQ-----------VPPTFENPKTETVSQ-------VA 3138
Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
GS + +T VSG P P V WL + ++ S RG + L + + P GTYTC
Sbjct: 3139 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGR--LQLSRLQPAQAGTYTCV 3196
Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL--------GQSVLISCAIAGDP 748
A N+ E R V+ V + PR ++ + GQ V + C G P
Sbjct: 3197 AENTQAEARKDFVVAV-----------LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQP 3245
Query: 749 FPTVHWLRDGKALCKDTG-HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
P V WL+DG L +D G H D +LVLK ++ AG Y + N GE
Sbjct: 3246 PPDVAWLKDGSPLGQDMGPHLRFYL--DGGSLVLKGLRASDAGAYTCVAHNPAGE 3298
Score = 148 bits (374), Expect = 4e-35
Identities = 204/819 (24%), Positives = 292/819 (35%), Gaps = 167/819 (20%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
EAP + + +G K GYP P ++W R Q + R +D +GT
Sbjct: 606 EAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDA--QGT-- 661
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L+I V ED G Y+C+ATN G Q TV L
Sbjct: 662 LIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD------------------------- 696
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
PP + V+V G+ C+ +G P P+V W +G + + + S S
Sbjct: 697 ---------PPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSS 747
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSD 270
K L I + D G YTC VN G AS +L++ ++
Sbjct: 748 GK-----LRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQL------------TE 790
Query: 271 VRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPR 330
+ ++VT + + + L + A + + +RG P +L + + S
Sbjct: 791 LPRDVTVELGRSALL-ACRATGRPPPTVTWRRGDGQPLGL----------RLGAGRGSRS 839
Query: 331 TAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLG 390
P + VL S V PE +AP +
Sbjct: 840 RQPDSGVLFFES---------VAPEDQAPYV---------------------------CE 863
Query: 391 SQDVVSKA-ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEV-SGIPKPEVAWF 448
+++V K A R+ + G A P+ S + V E Q V C V +G P PE W
Sbjct: 864 ARNVFGKVQAEARLIVTGH---APPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWL 920
Query: 449 LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLA 508
+G P+ GS GS L L +A +G YSC A+N G S VE
Sbjct: 921 KDGRPL--PPGSRHSIRADGS--LHLDRALQEHAGRYSCVATNTAG----SQHRDVE--L 970
Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV-AE 567
V++V P EG L C G P P ITW +
Sbjct: 971 VVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGT 1030
Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK--SEY-LLP---------- 614
L I +D G Y C A N +G S ++V+ S+ EY LLP
Sbjct: 1031 LLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQVQ 1090
Query: 615 --------VAPSKPTA-------------PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
S P P G LKV+ G + + GNP P+
Sbjct: 1091 VGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQ 1150
Query: 654 VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
+ W +G +Q RG Q S+ + D G Y CEA NSAG + L V
Sbjct: 1151 LSWSKDGVVLQG--------RGPQGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVL 1202
Query: 714 EPHDGTQPWFISKPRSVTASL-GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
EP W + + + G++ + C G P P V W R G + G V
Sbjct: 1203 EP----PHWGADETSGLLERVAGENASLPCPARGTPKPQVTW-RKGPSSEPLHGQPGVAV 1257
Query: 773 NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
E+ +L L V P +G YE N VG S + L++
Sbjct: 1258 LEE-GSLFLASVSPADSGDYECQATNEVGSTSRRAKLVV 1295
Score = 148 bits (373), Expect = 6e-35
Identities = 110/380 (28%), Positives = 175/380 (46%), Gaps = 44/380 (11%)
Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
C+ G P+P + W +G PV EG + S L + +D+GTY+CTA NA G
Sbjct: 4059 CKARGSPEPNITWDKDGQPVSGAEGKFTIQP---SGELLVKNLEGQDAGTYTCTAENAVG 4115
Query: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
+ L + V P F+++ D ++ G L+C+ RG+P PRI W +N +P+
Sbjct: 4116 RARRRVHLTIL------VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPV 4169
Query: 555 QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP 614
S + G + L ED GTY C AEN +G+ ++V V E
Sbjct: 4170 TEGVSEQDGG-STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKE------------ 4216
Query: 615 VAPSKPTAPIFLQG--LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 672
AP+ LQG S L G + + V G+P P++ W+ +G ++ S H
Sbjct: 4217 -------APV-LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQL 4268
Query: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTA 732
Q G SL I +D G Y C A N G + +L +Q + P F +P+ +T
Sbjct: 4269 QNG---SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQ-----SAPVFQVEPQDMTV 4320
Query: 733 SLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
G V + C G+P PT+ WL+ G+ L + + L + +L L+ V+ AG Y
Sbjct: 4321 RSGDDVALRCQATGEPTPTIEWLQAGQPL-RASRRLRTLPDG---SLWLENVETGDAGTY 4376
Query: 793 EILLKNRVGECSCQVSLMLQ 812
+ + N +G + + L+++
Sbjct: 4377 DCVAHNLLGSATARAFLVVR 4396
Score = 145 bits (366), Expect = 4e-34
Identities = 120/405 (29%), Positives = 178/405 (43%), Gaps = 44/405 (10%)
Query: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
A P + P + V CE SGIP+P + W EG V + +
Sbjct: 3946 ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVST----QVLPGGQ 4001
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
L + A D+G Y C A N+ G L V++V P + L D + EG
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRL------VVQVPPVIENGLPDLSTTEGSHA 4055
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA-ELHIQDALPEDHGTYTCLAENALG 590
L C RG+P P ITW +GQP+ A + EL +++ +D GTYTC AENA+G
Sbjct: 4056 FLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG 4115
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
+ +T+ +LPV + P D + G ++ + G+P
Sbjct: 4116 RARRRVHLTI----------LVLPVFTTLP---------GDRSLRLGDRLWLRCAARGSP 4156
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
P + W N + E EQ G +L V ED+GTY C A N G RTQAV
Sbjct: 4157 TPRIGWTVNDRPVTEGVS---EQDGGS-TLQRAAVSREDSGTYVCWAENRVG--RTQAVS 4210
Query: 711 TVQEPHDGTQPWFISKPRS-VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
V H P + S + +G S+ + C + GDP P +HW++DG L + +
Sbjct: 4211 FV---HVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL-RGSHLRH 4266
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
LQN +L + + + AG+Y+ L +N +G V L+LQ++
Sbjct: 4267 QLQNG---SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSA 4308
Score = 138 bits (347), Expect = 6e-32
Identities = 185/745 (24%), Positives = 273/745 (36%), Gaps = 117/745 (15%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCG---IRG 87
E PA P NL + A G P+P V W ++GQ + F L G +
Sbjct: 3762 EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLD----FRLQQGAYRLLP 3817
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
+ +L++ A +D ++ C +N G ++TV
Sbjct: 3818 SNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH----------------------- 3854
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
P+I + T + VV+ +C TG P P V+W K L AR
Sbjct: 3855 ---VPPTIADDQTDFTVTMMAPVVL--------TCHSTGIPAPTVSWSKAGAQL--GARG 3901
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------LDSANRSFV 261
S + LEI G YTC N +G A L++Q L S R+
Sbjct: 3902 SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVA 3961
Query: 262 RETKATNSDV----------RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
E + +KE NV + S + + S G A N
Sbjct: 3962 EEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKN 4021
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA--ARVQPEPR------------ 357
S +++L + P P L T S AR PEP
Sbjct: 4022 SAGSAMGKTRLV-VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG 4080
Query: 358 APGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFE 417
A G + PSGE + + A T +++ V +A RR+ + P F
Sbjct: 4081 AEGKFTIQPSGELLVKNLEGQDAGTYT----CTAENAVGRA-RRRVHLT---ILVLPVFT 4132
Query: 418 SKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKA 477
+ P + ++ + RC G P P + W + PV EG V E G L
Sbjct: 4133 TLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVT--EG---VSEQDGGSTLQRAAV 4187
Query: 478 RTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
DSGTY C A N G+ + V+ V++ +FS +++ G L C V
Sbjct: 4188 SREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQ-GEAFSYLVEPV----GGSIQLDCVV 4242
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
RG PVP I W+ +G P++ + + L I +D G Y CLAEN +G
Sbjct: 4243 RGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVA----- 4297
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
K +L + +AP+F D+ V G V + Q +G P P + WL
Sbjct: 4298 ----------KKVVILVL----QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL 4343
Query: 658 HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ-EPH 716
G ++ S G SL ++ V D GTY C A N G +A L V+ EP
Sbjct: 4344 QAGQPLRASRRLRTLPDG---SLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 4400
Query: 717 D--GTQPWFISKPRSVTASLGQSVL 739
G+ I+ + A+L SV+
Sbjct: 4401 GSWGSMTGVINGRKFGVATLNTSVM 4425
Score = 134 bits (336), Expect = 1e-30
Identities = 186/829 (22%), Positives = 285/829 (34%), Gaps = 196/829 (23%)
Query: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV 117
G P P + W +NG+P + +GT +L I V + G + C+ATN +G
Sbjct: 1715 GSPVPTIQWLQNGRPAEELAG--VQVASQGT-TLHIDHVELDHSGLFACQATNEAGTAGA 1771
Query: 118 TVELTVEGSFAK-----QLGQ----------------PVVSKTLGDRFSAPAVE---TRP 153
VE++V G +A +GQ P V + G P VE +
Sbjct: 1772 EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPG 1831
Query: 154 SIWGE-----------------------------------------------CPPKFATK 166
S+WGE PP
Sbjct: 1832 SLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPG 1891
Query: 167 LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226
V E C +G P P V+W KG+ P+ V+VS +VL I
Sbjct: 1892 PVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLS 1949
Query: 227 DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLD 286
D G Y C+ N +G + L + NV + +
Sbjct: 1950 DAGSYRCVASNVAGSTELRYGLRV--------------------------NVPPRITLPP 1983
Query: 287 SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSS-- 344
SL P +P + P + + +P + TP LQ
Sbjct: 1984 SL---------PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV 2034
Query: 345 ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPG--LGSQDVVSKAANRR 402
+TL +AR R + V S GE+R + P LG + VS AN
Sbjct: 2035 LTLASARASDSGRYSCVAV-SAVGEDR------QDVVLQVHMPPSILGEELNVSVVANES 2087
Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
+ +E Q + +P P ++W+ +G P+ + G
Sbjct: 2088 VALECQSHA----------------------------MPPPVLSWWKDGRPLEPRPG--- 2116
Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
V+ A L + +A D+G Y+C A N G + L V V + S + ++
Sbjct: 2117 VHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVR- 2175
Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHG 579
EG L C RG P P+I+W +GQP+ + + A L++ A G
Sbjct: 2176 ----EGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 2231
Query: 580 TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 639
TYTC N +G S + VH +P + P P + + V+
Sbjct: 2232 TYTCECSNVVGNSSQDLQLEVH-----------VPPQIAGPREP-----PTQVSVVQDGV 2275
Query: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
T+ +G PPP V W +G + + +G SL ++ TG Y+C A N
Sbjct: 2276 ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG--QSLHVERAQAAHTGRYSCVAEN 2333
Query: 700 SAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
AG + L+V P + + ++TA+L + + C G P P + W R
Sbjct: 2334 LAGRAERKFELSVLVPPELIGD--LDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR--- 2388
Query: 760 ALCKDTGHFEVLQNEDVFTLV------LKKVQPWHAGQYEILLKNRVGE 802
G V ED + L + + Q +G Y L N GE
Sbjct: 2389 ------GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGE 2431
Score = 132 bits (331), Expect = 4e-30
Identities = 130/463 (28%), Positives = 178/463 (38%), Gaps = 55/463 (11%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P+ SQ + VK C SG P P ++W E + QE S ++ DA L
Sbjct: 608 PQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQAL--QEDS-RIHVDA-QGTLI 663
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
+ D+G YSC A+N G + TL PS S+V V G++ VL
Sbjct: 664 IQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD------PPSVSAVNAVVLVAVGEEAVL 717
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
C G P PR+ W G + A +G +L I A D GTYTC A N LG S
Sbjct: 718 VCEASGVPPPRVIWYRGGLEMILAPEGSSSG--KLRIPAAQERDAGTYTCRAVNELGDAS 775
Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
+ V AP + D+ V G + + +G PPP
Sbjct: 776 AEIQLAVGH-------------------APQLTELPRDVTVELGRSALLACRATGRPPPT 816
Query: 654 VIWLH-NGNEIQESEDFHFEQRGTQHS---LCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
V W +G + R Q L + V PED Y CEA N G+V+ +A
Sbjct: 817 VTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEAR 876
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISC-AIAGDPFPTVHWLRDGKALCKDTGHF 768
L V P S +V GQ V + C +AG P P HWL+DG+ L + H
Sbjct: 877 LIVT---GHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHS 933
Query: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASC 828
+L L + HAG+Y + N G V L++Q +P P +
Sbjct: 934 IRADG----SLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQ------VPPRIHPTAT 983
Query: 829 EDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRG 871
+ GV A + G PA W +E + RG
Sbjct: 984 HHITNEGVPAS------LPCVASGVPAPTITWTKETNALTSRG 1020
Score = 128 bits (322), Expect = 5e-29
Identities = 110/377 (29%), Positives = 156/377 (41%), Gaps = 44/377 (11%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V V+ CE G+P P V+W +G P+ Q E S L L DSGT
Sbjct: 3418 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQS-----LEQGPS--LQLEAVGAGDSGT 3470
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
YSC A + G+ + L V +E S + ++ G L C +GTP P
Sbjct: 3471 YSCVAVSEAGEARRHFQLTVMEPPHIED----SGQPTELSLTPGAPMELLCDAQGTPQPN 3526
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
ITW +GQ + + A L ++DA G YTCLAE+ G + S V V
Sbjct: 3527 ITWHKDGQALTRLENNSRA-TRVLRVRDA-----GLYTCLAESPAGAIEKSFRVRVQA-- 3578
Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
P P P F+ GL+ Q+ + V P P++ W +G +Q
Sbjct: 3579 ---------PPNIVGPRGPRFVVGLAP------GQLVLECSVEAEPAPKITWHRDGIVLQ 3623
Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
E F +RG L +Q + D+G Y+C A N+AG + + T P
Sbjct: 3624 EDAHTQFPERG--RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-----TVPTIR 3676
Query: 725 SKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKV 784
S P +V S+ Q+ L+ C G P P V W +D L + FE+L +L ++ V
Sbjct: 3677 SGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPV 3733
Query: 785 QPWHAGQYEILLKNRVG 801
AG Y L N G
Sbjct: 3734 LAQDAGHYLCLASNSAG 3750
Score = 128 bits (321), Expect = 6e-29
Identities = 116/443 (26%), Positives = 177/443 (39%), Gaps = 43/443 (9%)
Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
V+ +C SG+P P+V W + PV ++V ED L + + D G Y C A
Sbjct: 1426 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDG--QVLRITGSHVGDEGRYQCVAF 1483
Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSF--SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 548
+ GQ + + L+V P+ S+ + AV+E L C RG P P ITW
Sbjct: 1484 SPAGQQARDFQLRVH------APPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWF 1537
Query: 549 LNGQPIQYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607
+G + + G +L + A D G YTC A NA+G +K++R
Sbjct: 1538 KDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAA----------EKATR 1587
Query: 608 KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
Y+ P P + K + G V + G+P P + W H G + ES
Sbjct: 1588 LDVYVPPTIEGAGGRPYVV------KAVAGRPVALECVARGHPSPTLSWHHEGLPVAESN 1641
Query: 668 DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP 727
+ E G+ L ++ +G Y+C A + AGE Q + VQ P Q
Sbjct: 1642 ESRLETDGSV--LRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVP---PQLLVAEGL 1696
Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 787
VT +GQ + + C +G P PT+ WL++G+ + G Q TL + V+
Sbjct: 1697 GQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT---TLHIDHVELD 1753
Query: 788 HAGQYEILLKNRVGECSCQVSLMLQNSSARA---LPRGREPASCEDLCGGGVGAD----- 839
H+G + N G +V + + A +P G+ E D
Sbjct: 1754 HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 1813
Query: 840 GGGSDRYGSLRPGWPARGQGWLE 862
G G+ L GW + G W E
Sbjct: 1814 GWGAHPKPPLVEGWCSPGSLWGE 1836
Score = 126 bits (316), Expect = 2e-28
Identities = 105/399 (26%), Positives = 166/399 (41%), Gaps = 47/399 (11%)
Query: 413 FPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472
FP ES + V+E CE G+P P+++W +G P+ + ++ + A L
Sbjct: 2164 FPLRES--HTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQ-HVSAVGRLL 2220
Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE---RLAVMEVAPSFSSVLKDCAVIEGQ 529
L +A+ GTY+C SN G S L+V ++A P+ SV++D
Sbjct: 2221 YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVA---- 2276
Query: 530 DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV------AELHIQDALPEDHGTYTC 583
L+C+ G P P +TW +GQP+ E G+ LH++ A G Y+C
Sbjct: 2277 --TLECNATGKPPPTVTWERDGQPV-----GAELGLQLQNQGQSLHVERAQAAHTGRYSC 2329
Query: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
+AEN G ++ RK E + V P L L+++ S +T+
Sbjct: 2330 VAENLAG-------------RAERKFELSVLVPPELIGD---LDPLTNITAALHSPLTLL 2373
Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
+ G PPP + W + ED + G L + + +D+G Y+C A N AGE
Sbjct: 2374 CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWM--LKMTQTQEQDSGLYSCLASNEAGE 2431
Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
R + V P + GQ+ + C + G P P + W +DG+ L +
Sbjct: 2432 ARRNFSVEVLVPPSIENE---DLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLAR 2488
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
H + D L + + AG Y + N VGE
Sbjct: 2489 GDAHH---ISPDGVLLQVLQANLSSAGHYSCIAANAVGE 2524
Score = 124 bits (311), Expect = 9e-28
Identities = 113/433 (26%), Positives = 165/433 (38%), Gaps = 53/433 (12%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P E P ++ V EN +V C SG+P P+V+WF PV G V L
Sbjct: 1886 PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTVSVDGRVLR 1942
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
+ +A+ D+G+Y C ASN G + L+V + + PS V+ L
Sbjct: 1943 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPG-----PVLVNTPVRL 1997
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
C+ G P P + WL +G P+ A + G L + A D G Y+C+A +A+G
Sbjct: 1998 TCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVG 2057
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
+ + VH P L ++ V+ V + Q P
Sbjct: 2058 EDRQDVVLQVH-------------------MPPSILGEELNVSVVANESVALECQSHAMP 2098
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
PP + W +G ++ H + L + D G YTCEA N AG
Sbjct: 2099 PPVLSWWKDGRPLEPRPGVHLS--ADKALLQVDRADVWDAGHYTCEALNQAGH------- 2149
Query: 711 TVQEPHDGTQPWF-----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
E H W + + ++T G +SC G PFP + W +DG+ L
Sbjct: 2150 --SEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL---P 2204
Query: 766 GHFEVLQNEDVF--TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGR 823
G LQ+ L L + Q G Y N VG S + L + A P R
Sbjct: 2205 GEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGP--R 2262
Query: 824 EPASCEDLCGGGV 836
EP + + GV
Sbjct: 2263 EPPTQVSVVQDGV 2275
Score = 119 bits (298), Expect = 3e-26
Identities = 109/396 (27%), Positives = 163/396 (41%), Gaps = 40/396 (10%)
Query: 423 QEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
+E+ EN C+ + IP P++ W+ E P+ + EV G L + R ++
Sbjct: 2760 REIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGD---EVSVLQGGRVLQIPLVRAENA 2816
Query: 483 GTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
G YSC ASN G+ + L V L + ++++ V LQC G PV
Sbjct: 2817 GRYSCKASNEVGEDWLHYELLV--LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPV 2874
Query: 543 PRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
P I+WL NG P + E G L + A D +Y C+AEN G
Sbjct: 2875 PTISWLQNGLPFSPSPRLQVLEDGQV-LQVSTAEVADAASYMCVAENQAG---------- 2923
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
+E L + P L L + + S V++ V +P PEV W +
Sbjct: 2924 -------SAEKLFTLRVQVPPRIAGLD-LEQVTAILNSSVSLPCDVHAHPNPEVTWYKDS 2975
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
+ E+ F GT H+L + D+G YTCEA N+AG + L+V P
Sbjct: 2976 QALSLGEEV-FLLPGT-HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP----- 3028
Query: 721 PWFISKPR----SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
P F PR +V +G ++SC P PTV W +DG+ L + L+
Sbjct: 3029 PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVL-AQRTQALRGGQ- 3086
Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
L +++ Q G Y + N GE +L +Q
Sbjct: 3087 -RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ 3121
Score = 119 bits (297), Expect = 4e-26
Identities = 99/385 (25%), Positives = 157/385 (40%), Gaps = 45/385 (11%)
Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
C V P P++ W +G + QE + + + G +L L T DSG YSCTA NA G
Sbjct: 3603 CSVEAEPAPKITWHRDGIVL--QEDAHTQFPERG-RFLQLQALSTADSGDYSCTARNAAG 3659
Query: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
S ++ +++ + + P +V + Q +L C G P P ++W + P+
Sbjct: 3660 STSVAFRVEIHTVPTIRSGPPAVNVSVN------QTALLPCQADGVPAPLVSWRKDRVPL 3713
Query: 555 QYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 613
E L IQ L +D G Y CLA N+ G S R+ L
Sbjct: 3714 DPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG--------------SDRQGRDLR 3759
Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673
+ P P S+L + + + + SG+P P V+W +G ++ DF +Q
Sbjct: 3760 VLEP-----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL----DFRLQQ 3810
Query: 674 RGTQ----HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729
+ ++L + P+D+ + C N GE +TV P P
Sbjct: 3811 GAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVP-----PTIADDQTD 3865
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
T ++ V+++C G P PTV W + G L + V + L + + P HA
Sbjct: 3866 FTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHA 3922
Query: 790 GQYEILLKNRVGECSCQVSLMLQNS 814
G+Y +N G V L +Q S
Sbjct: 3923 GRYTCSARNSAGVAHKHVFLTVQAS 3947
Score = 118 bits (296), Expect = 5e-26
Identities = 106/390 (27%), Positives = 145/390 (37%), Gaps = 41/390 (10%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V +T C V G + W + + G + D ++ D G
Sbjct: 528 VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPT---DGGR 584
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y C ASNA G S L V AP S +G + + CS G P P
Sbjct: 585 YQCVASNANGVTRASVWLLVRE------APQVSIHTSSQHFSQGVEVKVSCSASGYPTPH 638
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
I+W Q +Q L IQ PED G Y+C A N +G + VT++
Sbjct: 639 ISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVG--TDQETVTLY--- 693
Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
Y P + S A + V G + + + SG PPP VIW G E+
Sbjct: 694 ------YTDPPSVSAVNAVVL--------VAVGEEAVLVCEASGVPPPRVIWYRGGLEMI 739
Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
+ + + L I D GTYTC A N G+ + L V G P
Sbjct: 740 LAPE-----GSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV-----GHAPQLT 789
Query: 725 SKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-DGK--ALCKDTGHFEVLQNEDVFTLVL 781
PR VT LG+S L++C G P PTV W R DG+ L G + D L
Sbjct: 790 ELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFF 849
Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLML 811
+ V P Y +N G+ + L++
Sbjct: 850 ESVAPEDQAPYVCEARNVFGKVQAEARLIV 879
Score = 118 bits (296), Expect = 5e-26
Identities = 106/388 (27%), Positives = 155/388 (39%), Gaps = 48/388 (12%)
Query: 419 KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
+P + ++ C+ G P+P + W +G + R E + R
Sbjct: 3501 QPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR----------VLR 3550
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
RD+G Y+C A + G + S+ ++V+ + V P + A GQ VL+CSV
Sbjct: 3551 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLA--PGQ-LVLECSVE 3606
Query: 539 GTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
P P+ITW +G +Q A + L +Q D G Y+C A NA G S +
Sbjct: 3607 AEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFR 3666
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
V +H T P G + V + Q G P P V W
Sbjct: 3667 VEIH-------------------TVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWR 3707
Query: 658 HNGNEIQ-ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716
+ + S F G SL IQ V +D G Y C A NSAG R L V EP
Sbjct: 3708 KDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEP- 3763
Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL--CKDTGHFEVLQNE 774
P P ++T + L+ C +G P P V W +DG+ L G + +L +
Sbjct: 3764 ----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 3819
Query: 775 DVFTLVLKKVQPWHAGQYEILLKNRVGE 802
L+L P + Q+E ++ N VGE
Sbjct: 3820 ---ALLLTAPGPQDSAQFECVVSNEVGE 3844
Score = 117 bits (293), Expect = 1e-25
Identities = 108/407 (26%), Positives = 169/407 (41%), Gaps = 39/407 (9%)
Query: 414 PKFESKPQSQEVK--ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
P E++ + +K + QT C V+G P+P++ WF +G P+ R + +
Sbjct: 2444 PSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAH---HISPDGVL 2500
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
L +L+A +G YSC A+NA G+ + + L V LA + + S ++ V
Sbjct: 2501 LQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV-LLAPTILGGAEDSADEEVTVTVNNPI 2559
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
L C P P ITW+ +G P + +R+ G L I +A ED G YTC+ N LG
Sbjct: 2560 SLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 2619
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
E + E L+P + SK P+ G+ ++K S +T+ + P
Sbjct: 2620 -----------EAVKNYHVEVLIPPSISKDD-PLGEVGVKEVKTKVNSTLTLECESWAVP 2667
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE------V 704
PP + W +G + S + G L IQ D+G Y C A N AGE V
Sbjct: 2668 PPTIRWYKDGQPVTPSS--RLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNV 2725
Query: 705 RTQAVLTVQEPHDGTQPW-FISKPRSVTASL--------GQSVLISCAIAGDPFPTVHWL 755
Q Q+ D + + +S+ + + C P P + W
Sbjct: 2726 LIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWY 2785
Query: 756 RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
R+ + L VLQ V + L + + +AG+Y N VGE
Sbjct: 2786 REDQPLSAG-DEVSVLQGGRVLQIPLVRAE--NAGRYSCKASNEVGE 2829
Score = 117 bits (292), Expect = 1e-25
Identities = 105/406 (25%), Positives = 158/406 (38%), Gaps = 50/406 (12%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P S P + V NQT C+ G+P P V+W + P+ + E+ + L
Sbjct: 3673 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS---LR 3729
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
+ +D+G Y C ASN+ G L+V L +APS S++ + +L
Sbjct: 3730 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRV--LEPPAIAPSPSNL----TLTAHTPALL 3783
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDAL------PEDHGTYTCLAEN 587
C G+P P + W +GQ + + + G L +AL P+D + C+ N
Sbjct: 3784 PCEASGSPKPLVVWWKDGQKLDF---RLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 3840
Query: 588 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
+G+ VTVH P +D V + V +T +
Sbjct: 3841 EVGEAHRLYQVTVH-------------------VPPTIADDQTDFTVTMMAPVVLTCHST 3881
Query: 648 GNPPPEVIWLHNGNEI-QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 706
G P P V W G ++ + G +L I + P G YTC A NSAG
Sbjct: 3882 GIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHAGRYTCSARNSAGVAHK 3938
Query: 707 QAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG 766
LTVQ P P V A + VL+ C +G P PT+ W ++G +
Sbjct: 3939 HVFLTVQ-----ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVS 3993
Query: 767 HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
+VL L + P AG Y + KN G + L++Q
Sbjct: 3994 -TQVLPGGQ---LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 4035
Score = 115 bits (289), Expect = 3e-25
Identities = 92/379 (24%), Positives = 158/379 (41%), Gaps = 42/379 (11%)
Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTY 485
+ + V C V G P V+W +G P+ + ++ H L + K + D+G +
Sbjct: 3326 RPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL---HGSGHTLRISKVQLADAGIF 3382
Query: 486 SCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRI 545
+C A++ G ++TLQV+ V+E D V+ G L C RG P+P +
Sbjct: 3383 TCVAASPAGVADRNFTLQVQVPPVLEPV----EFQNDVVVVRGSLVELPCEARGVPLPLV 3438
Query: 546 TWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
+W+ +G+P+ + E G L ++ D GTY+C+A + G+ +TV E
Sbjct: 3439 SWMKDGEPL--LSQSLEQG-PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 3495
Query: 606 SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
S +PT +L + G+ + + G P P + W +G +
Sbjct: 3496 IEDS--------GQPT---------ELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR 3538
Query: 666 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
E+ +S + + D G YTC A + AG + + VQ P + P
Sbjct: 3539 LEN---------NSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGP---R 3586
Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
PR V +++ C++ +P P + W RDG L +D H + + L L+ +
Sbjct: 3587 GPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQED-AHTQFPERGRF--LQLQALS 3643
Query: 786 PWHAGQYEILLKNRVGECS 804
+G Y +N G S
Sbjct: 3644 TADSGDYSCTARNAAGSTS 3662
Score = 114 bits (285), Expect = 9e-25
Identities = 105/389 (26%), Positives = 167/389 (42%), Gaps = 45/389 (11%)
Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
CE GIP P + WF PV E + Y AG L + + + +DSG YSC ASN G
Sbjct: 2374 CEAMGIPPPAIRWFRGEEPVSPGE---DTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 2430
Query: 495 QLSCSWTLQVERLAVMEVAPSFSS--VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
+ +++++V V PS + + + V++GQ L C+V G P P++TW +G+
Sbjct: 2431 EARRNFSVEV------LVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGR 2484
Query: 553 PIQY--ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
P+ A GV L + A G Y+C+A NA+G EK +
Sbjct: 2485 PLARGDAHHISPDGVL-LQVLQANLSSAGHYSCIAANAVG-----------EKTKHFQLS 2532
Query: 611 YLLPVAPSKPTAPIFLQGLSD-----LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
LL AP L G D + V + +++ + P P + W+ +G +
Sbjct: 2533 VLL--------APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEA 2584
Query: 666 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPH-DGTQPWF 723
S + GT H L I ED G YTC N GE V+ V + P P
Sbjct: 2585 SRNIQL-LPGT-HGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLG 2642
Query: 724 ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKK 783
+ V + ++ + C P PT+ W +DG+ + + +VL + L ++
Sbjct: 2643 EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPV-TPSSRLQVLGEGRL--LQIQP 2699
Query: 784 VQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
Q +G+Y + N GE ++++Q
Sbjct: 2700 TQVSDSGRYLCVATNVAGEDDQDFNVLIQ 2728
Score = 110 bits (274), Expect = 2e-23
Identities = 90/360 (25%), Positives = 142/360 (39%), Gaps = 41/360 (11%)
Query: 464 YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523
++++G+ +L+A + GTY CTA + G T + + V+ P +
Sbjct: 473 FQESGNSSWEILRASKAEEGTYECTAVSRAG------TGRAKAQIVVTDPPPQLVPAPNV 526
Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHIQDALPEDHGTYT 582
V G+ VL C V G +TW+ + + + + + L I +P D G Y
Sbjct: 527 TVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQ 586
Query: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 642
C+A NA G S W+ V E AP S G +V +
Sbjct: 587 CVASNANGVTRASVWLLVRE-------------------APQVSIHTSSQHFSQGVEVKV 627
Query: 643 TVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
+ SG P P + W +QE H + +GT L IQ V PED G Y+C+A N G
Sbjct: 628 SCSASGYPTPHISWSRESQALQEDSRIHVDAQGT---LIIQGVAPEDAGNYSCQATNEVG 684
Query: 703 EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
+ L +P P + V ++G+ ++ C +G P P V W R G +
Sbjct: 685 TDQETVTLYYTDP-----PSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEM- 738
Query: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS-SARALPR 821
+ L + Q AG Y N +G+ S ++ L + ++ LPR
Sbjct: 739 -----ILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPR 793
Score = 110 bits (274), Expect = 2e-23
Identities = 78/289 (26%), Positives = 125/289 (43%), Gaps = 26/289 (8%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V E+ V+ CE G+P P + WF +G + S +V G L L +A++ D+G
Sbjct: 1514 VMEDHLVQLLCEARGVPTPNITWFKDGALLPT---STKVVYTRGGRQLQLGRAQSSDAGV 1570
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+C ASNA G + L V +E A V+K + G+ L+C RG P P
Sbjct: 1571 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVK---AVAGRPVALECVARGHPSPT 1627
Query: 545 ITWLLNGQPIQYAR-STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
++W G P+ + S E + L ++ G Y+C+A + G+ V V
Sbjct: 1628 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQV- 1686
Query: 604 KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI 663
P + +GL + + G + + Q SG+P P + WL NG
Sbjct: 1687 ----------------PPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPA 1730
Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+E +GT +L I V + +G + C+A N AG + ++V
Sbjct: 1731 EELAGVQVASQGT--TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 1777
Score = 106 bits (264), Expect = 2e-22
Identities = 121/509 (23%), Positives = 192/509 (37%), Gaps = 60/509 (11%)
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
+ K N T+ CE +P P + W+ +G PV ++V + L + + DSG
Sbjct: 2650 KTKVNSTLTLECESWAVPPPTIRWYKDGQPVT-PSSRLQVLGEG--RLLQIQPTQVSDSG 2706
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA--------------VIEGQ 529
Y C A+N G+ + + ++ + + FS+ + + ++E
Sbjct: 2707 RYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 2766
Query: 530 DFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
L C P P +TW QP+ + G L I E+ G Y+C A N
Sbjct: 2767 PAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNE 2826
Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL----QGLSDLKVMDGSQVTMTV 644
+G+ W+ Y L V T P+ L + + ++ V S V++
Sbjct: 2827 VGE----DWL-----------HYELLVL----TPPVILGDTEELVEEVTVNASSTVSLQC 2867
Query: 645 QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
GNP P + WL NG S + G + EV D +Y C A N AG
Sbjct: 2868 PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV--ADAASYMCVAENQAGSA 2925
Query: 705 RTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
L VQ P P VTA L SV + C + P P V W +D +AL
Sbjct: 2926 EKLFTLRVQVP-----PRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSL 2980
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL-MLQNSSARALPRG 822
EV TL L + + +G Y N G V L +L + R PRG
Sbjct: 2981 GE---EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRG 3037
Query: 823 REPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH 882
+ A + G +D W GQ + + + +RG + ++ Q
Sbjct: 3038 PQDAVLVRV--GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQV 3095
Query: 883 TEEAIRQQEVEQLDFRDLLGKKVSTKTLS 911
+++ + +V ++ G+ V T TL+
Sbjct: 3096 SDKGLYSCKVS-----NVAGEAVRTFTLT 3119
Score = 105 bits (263), Expect = 3e-22
Identities = 172/797 (21%), Positives = 286/797 (35%), Gaps = 153/797 (19%)
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIW 156
H ++ G + E S A + T E T VS+ R A V T P
Sbjct: 472 HFQESGNSSWEILRASKAEEGTYECTA------------VSRAGTGRAKAQIVVTDP--- 516
Query: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
PP+ V V G+ SC++ G +TW++ + + P++ V++ +
Sbjct: 517 ---PPQLVPA-PNVTVSPGETAVLSCRVLGEAPYNLTWVR-DWRVLPASTGRVAQLADLS 571
Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ-----GLDSANRSFVR--ETKATNS 269
LEI G+ D G Y C+ N +G S L ++ + ++++ F + E K + S
Sbjct: 572 -LEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCS 630
Query: 270 DVRKEVTNV--------ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321
++ + ++S++ +P+ G+ A ++ +E+
Sbjct: 631 ASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETV 690
Query: 322 LESCKDSPRTAPQTPVLQKT--SSSITLQAARVQPEPRA----PGLG-VLSPSGEERKRP 374
D P + V+ ++ + A P PR GL +L+P G +
Sbjct: 691 TLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGKL 750
Query: 375 APPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFR 434
P R G + V++ + ++ A P+ P+ V+ ++
Sbjct: 751 RIP---AAQERDAGTYTCRAVNELGDASAEIQLAVGHA-PQLTELPRDVTVELGRSALLA 806
Query: 435 CEVSGIPKPEVAWFL-EGTPVRRQ----EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTA 489
C +G P P V W +G P+ + GS D+G L D Y C A
Sbjct: 807 CRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG--VLFFESVAPEDQAPYVCEA 864
Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV-RGTPVPRITWL 548
N G++ L V A ++A S +V V+EGQ L C V G P+P WL
Sbjct: 865 RNVFGKVQAEARLIVTGHAPPQIASSAPTV----RVLEGQPVSLPCIVLAGRPLPERHWL 920
Query: 549 LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 608
+G+P+ LH+ AL E G Y+C+A N G R
Sbjct: 921 KDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAG-------------SQHRD 967
Query: 609 SEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI-QES 666
E ++ V P PTA + +G ++ SG P P + W N +
Sbjct: 968 VELVVQVPPRIHPTATHHITN-------EGVPASLPCVASGVPAPTITWTKETNALTSRG 1020
Query: 667 EDFHFEQRGT-------------------------------------------------- 676
++ + GT
Sbjct: 1021 PHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLP 1080
Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQ 736
SL + +V D+G Y C A N AG + VL VQ P P PR + +G+
Sbjct: 1081 SGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVP-----PQVQPGPRVLKVLVGE 1135
Query: 737 SVLISCAIAGDPFPTVHWLRDGKAL----CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
++ ++C G+P P + W +DG L + + HF ++ D AG+Y
Sbjct: 1136 ALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRTSD-------------AGRY 1182
Query: 793 EILLKNRVGECSCQVSL 809
N G + +V L
Sbjct: 1183 RCEASNSAGVDAWEVEL 1199
Score = 103 bits (256), Expect = 2e-21
Identities = 99/411 (24%), Positives = 165/411 (40%), Gaps = 64/411 (15%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV--RRQEGSIEVYEDAGSHY 471
P+ + P+ +V + + C G P+P+++W +G + R +GS+ H+
Sbjct: 1120 PQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSV--------HF 1171
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
+ RT D+G Y C ASN+ G +W +++ L +S L + + G++
Sbjct: 1172 AAI---RTSDAGRYRCEASNSAG--VDAWEVELRVLEPPHWGADETSGLLE--RVAGENA 1224
Query: 532 VLQCSVRGTPVPRITWL-------LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584
L C RGTP P++TW L+GQP + E G L + P D G Y C
Sbjct: 1225 SLPCPARGTPKPQVTWRKGPSSEPLHGQP---GVAVLEEG--SLFLASVSPADSGDYECQ 1279
Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTV 644
A N +G S A + V+ S R+ +++ M G +T+
Sbjct: 1280 ATNEVGSTSRRAKLVVYVPPSIRED-----------------GRKANVSGMAGQSLTLEC 1322
Query: 645 QVSGNPPPEVIWLHNGNEI-------QESEDFHFEQRGTQ------HSLCIQEVFPEDTG 691
+G P PE++WL + + D + Q G SL + D+G
Sbjct: 1323 DANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSG 1382
Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
Y+C A N AG + L V P + V G V + C +G P P
Sbjct: 1383 LYSCRAENQAGTAQRDFHLLVLTP---PSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQ 1439
Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
V W +D + + H +V ++ V + V G+Y+ + + G+
Sbjct: 1440 VEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV--GDEGRYQCVAFSPAGQ 1488
Score = 98.6 bits (244), Expect = 5e-20
Identities = 100/403 (24%), Positives = 152/403 (37%), Gaps = 52/403 (12%)
Query: 429 QTVKFRCEVSGIPKPEVAWF----LEGTPVR----------RQEGSIEVYEDAGSHYLCL 474
Q++ C+ +G P PE+ W L G P+ Q G + ++ S L
Sbjct: 1316 QSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQS--LHF 1373
Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
+ + DSG YSC A N G + L V + A + VL + G D LQ
Sbjct: 1374 PRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLG----LAGADVELQ 1429
Query: 535 CSVRGTPVPRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
C G P P++ W + QP+ + L I + D G Y C+A + GQ
Sbjct: 1430 CWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQ 1489
Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG---LSDLKVMDGSQVTMTVQVSGN 649
+ + VH AP + G ++ VM+ V + + G
Sbjct: 1490 ARDFQLRVH--------------------APPTIWGSNETGEVAVMEDHLVQLLCEARGV 1529
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
P P + W +G + S + + G Q L + D G YTC+A N+ G
Sbjct: 1530 PTPNITWFKDGALLPTSTKVVYTRGGRQ--LQLGRAQSSDAGVYTCKASNAVGAAEKATR 1587
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
L V P T +P V A G+ V + C G P PT+ W +G + + E
Sbjct: 1588 LDVYVP--PTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESN---E 1642
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
D L L+ +G Y + + GE Q S+ +Q
Sbjct: 1643 SRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 1685
Score = 96.7 bits (239), Expect = 2e-19
Identities = 107/408 (26%), Positives = 149/408 (36%), Gaps = 33/408 (8%)
Query: 419 KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
+P + + V C G P P ++W EG PV E + E GS L L
Sbjct: 1602 RPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVA--ESNESRLETDGS-VLRLESPG 1658
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
SG YSC AS+ G+ ++++V+ + VA V I GQ L C
Sbjct: 1659 EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQV----TTIVGQPLELPCQAS 1714
Query: 539 GTPVPRITWLLNGQPIQYARSTCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
G+PVP I WL NG+P + A LHI + G + C A N G
Sbjct: 1715 GSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVE 1774
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPI-----FLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
V+VH + AP PI + S V PP
Sbjct: 1775 VSVHGE-----------WAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPL 1823
Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
W G+ E L I++V D G YTC A N AGE + + L V
Sbjct: 1824 VEGWCSPGSLWGEPTGIPVAY-SLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKV 1882
Query: 713 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
P +P ++K A SV + C +G P P V W + + + G V
Sbjct: 1883 LVP-PNIEPGPVNKAVLENA----SVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTV 1934
Query: 773 NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
+ D L +++ Q AG Y + N G + L + LP
Sbjct: 1935 SVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLP 1982
Score = 91.3 bits (225), Expect = 8e-18
Identities = 90/313 (28%), Positives = 127/313 (40%), Gaps = 43/313 (13%)
Query: 454 VRRQEGSIEVYEDAG---SHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510
V R S V+E+ G S L L + + DSG Y CTASN G S + L V+ +
Sbjct: 1063 VNRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQV 1122
Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI 570
+ P VLK V+ G+ L C G P P+++W +G +Q A +
Sbjct: 1123 QPGPR---VLK---VLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRT 1176
Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
DA G Y C A N+ G AW E L V GL
Sbjct: 1177 SDA-----GRYRCEASNSAG---VDAW------------EVELRVLEPPHWGADETSGL- 1215
Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT----QHSLCIQEVF 686
L+ + G ++ G P P+V W + SE H Q G + SL + V
Sbjct: 1216 -LERVAGENASLPCPARGTPKPQVTWRKGPS----SEPLH-GQPGVAVLEEGSLFLASVS 1269
Query: 687 PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAG 746
P D+G Y C+A N G +A L V P + + +V+ GQS+ + C G
Sbjct: 1270 PADSGDYECQATNEVGSTSRRAKLVVYVPPSIRED---GRKANVSGMAGQSLTLECDANG 1326
Query: 747 DPFPTVHWLRDGK 759
P P + WL+D +
Sbjct: 1327 FPVPEIVWLKDAQ 1339
Score = 78.2 bits (191), Expect = 7e-14
Identities = 68/238 (28%), Positives = 93/238 (39%), Gaps = 43/238 (18%)
Query: 20 DPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR-NGQPITSGGR 78
D S + + AP PR++ ++ G +A R G P P VTW R +GQP+ G R
Sbjct: 773 DASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL--GLR 830
Query: 79 FLLDCGIRG----TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQP 134
G R + L +V ED+ Y CEA N G Q
Sbjct: 831 LGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQ------------------ 872
Query: 135 VVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSC-KITGRPQPQVT 193
E R + G PP+ A+ V V EGQ C + GRP P+
Sbjct: 873 --------------AEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERH 918
Query: 194 WLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
WLK PL P +R S+ L + Q+ G Y+C+ N +G EL +Q
Sbjct: 919 WLKDGRPLPPGSRHSIRADGS---LHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQ 973
Score = 77.0 bits (188), Expect = 2e-13
Identities = 95/394 (24%), Positives = 136/394 (34%), Gaps = 60/394 (15%)
Query: 429 QTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCT 488
Q ++ C+ SG P P + W G P G + H + SG ++C
Sbjct: 1705 QPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLH---IDHVELDHSGLFACQ 1761
Query: 489 ASNAQGQLSCSWTLQVERLAVMEVAPSFSSV---LKDCAVIEGQDFVLQCS--------- 536
A+N G +VE E AP V F C
Sbjct: 1762 ATNEAGTAGA----EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGA 1817
Query: 537 ------VRGTPVPRITW-LLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
V G P W G P+ Y+ L I+ D G YTC A N
Sbjct: 1818 HPKPPLVEGWCSPGSLWGEPTGIPVAYSLPP------PLQIEKVDLRDEGIYTCAATNLA 1871
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G+ S R+ + V P+ P+ + V++ + VT+ SG
Sbjct: 1872 GE-------------SKREVALKVLVPPNIEPGPV------NKAVLENASVTLECLASGV 1912
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
PPP+V W + G L I++ D G+Y C A N AG +
Sbjct: 1913 PPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLSDAGSYRCVASNVAGSTELRYG 1970
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC-KDTGHF 768
L V P T P + P V V ++C G P PT+ WL+DG + T
Sbjct: 1971 LRVNVPPRITLPPSLPGPVLVNT----PVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGL 2026
Query: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
+V V TL + +G+Y + + VGE
Sbjct: 2027 QVFPGGRVLTLASARAS--DSGRYSCVAVSAVGE 2058
Score = 73.9 bits (180), Expect = 1e-12
Identities = 59/214 (27%), Positives = 86/214 (40%), Gaps = 42/214 (19%)
Query: 33 PAFILPPRN----LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
PAF PR + ++ G A PEP VTW+++GQP+ R +RG
Sbjct: 3029 PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQR---TQALRGG 3085
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
L I D+G Y+C+ +N +G T LTV+ + F P
Sbjct: 3086 QRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ---------------VPPTFENPK 3130
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
ET + G P T C ++G P P VTWLK +P++ SA
Sbjct: 3131 TETVSQVAGS--PLVLT----------------CDVSGVPAPTVTWLKDRMPVESSAVHG 3172
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
V + G L++ + G YTC+ N +A
Sbjct: 3173 VVSRGGR--LQLSRLQPAQAGTYTCVAENTQAEA 3204
Score = 72.0 bits (175), Expect = 5e-12
Identities = 59/207 (28%), Positives = 83/207 (40%), Gaps = 42/207 (20%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLL---DCGIRGTFSLVIHAVHEEDRGK 103
GA + + G P PQV W ++ QP+ GG L D + L I H D G+
Sbjct: 1423 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV-----LRITGSHVGDEGR 1477
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C A + +G + +L V AP P+IWG
Sbjct: 1478 YQCVAFSPAGQQARDFQLRVH---------------------AP-----PTIWG------ 1505
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
+ + G V V E + + C+ G P P +TW K L S +V V + G Q L++
Sbjct: 1506 SNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKV-VYTRGGRQ-LQLGRA 1563
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSI 250
D GVYTC N G A + L +
Sbjct: 1564 QSSDAGVYTCKASNAVGAAEKATRLDV 1590
Score = 69.3 bits (168), Expect = 3e-11
Identities = 57/220 (25%), Positives = 84/220 (38%), Gaps = 35/220 (15%)
Query: 32 APAFIL-PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
AP F L L ++EG RG P P+++W ++GQP+ G L G
Sbjct: 2161 APVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL- 2219
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + G YTCE +N G ++L V
Sbjct: 2220 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQL--------------------------EVH 2253
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
P I G P VV++G + C TG+P P VTW + P+ A + +
Sbjct: 2254 VPPQIAGPREPPTQVS----VVQDG-VATLECNATGKPPPTVTWERDGQPV--GAELGLQ 2306
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+N Q L + G Y+C+ N +G+A ELS+
Sbjct: 2307 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSV 2346
Score = 68.6 bits (166), Expect = 6e-11
Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 48/246 (19%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
A + + +T +V V P+ + AF L G + + + VRG P P + W
Sbjct: 4199 AENRVGRTQ-AVSFVHVKEAPVLQGEAFSY----LVEPVGGSIQLDCVVRGDPVPDIHWI 4253
Query: 68 RNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
++G P+ R L G SL IH +D G+Y C A N G + V L ++
Sbjct: 4254 KDGLPLRGSHLRHQLQNG-----SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQ-- 4306
Query: 127 FAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186
SAP + P + V+ G C+ TG
Sbjct: 4307 ------------------SAPVFQVEPQ--------------DMTVRSGDDVALRCQATG 4334
Query: 187 RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
P P + WL+ PL+ S R+ L + V D G Y C+ N G A+ A
Sbjct: 4335 EPTPTIEWLQAGQPLRASRRLRTLPDGS---LWLENVETGDAGTYDCVAHNLLGSATARA 4391
Query: 247 ELSIQG 252
L ++G
Sbjct: 4392 FLVVRG 4397
Score = 68.2 bits (165), Expect = 7e-11
Identities = 57/238 (23%), Positives = 91/238 (38%), Gaps = 52/238 (21%)
Query: 16 SLSVDPSRVDSM-PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
S+ V P + + PLT A + P L + G P P + W R +P++
Sbjct: 2345 SVLVPPELIGDLDPLTNITAALHSPLTLLCE----------AMGIPPPAIRWFRGEEPVS 2394
Query: 75 SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLG 132
G L + G + L + E+D G Y+C A+N G R +VE+ V S +
Sbjct: 2395 PGEDTYL---LAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDL 2451
Query: 133 QPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192
+ V+ V +GQ C +TG PQP++
Sbjct: 2452 EEVIK----------------------------------VLDGQTAHLMCNVTGHPQPKL 2477
Query: 193 TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
TW K PL +S +L++ N G Y+C+ N G+ + +LS+
Sbjct: 2478 TWFKDGRPLARGDAHHISPDG--VLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 2533
Score = 67.4 bits (163), Expect = 1e-10
Identities = 58/214 (27%), Positives = 85/214 (39%), Gaps = 46/214 (21%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG----RFLLDCGIRGTFSLVIHAVHEE 99
+ EG + + G P P V W ++G P+ RF LD G SLV+ +
Sbjct: 3229 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-----SLVLKGLRAS 3283
Query: 100 DRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
D G YTC A N +G AR TV + V P+I
Sbjct: 3284 DAGAYTCVAHNPAGEDARLHTVNVLVP----------------------------PTI-- 3313
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+ A G +V + G++ C + G P V+WLK +PL S R +
Sbjct: 3314 ---KQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSG--HT 3368
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
L I V D G++TC+ + +G A + L +Q
Sbjct: 3369 LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 3402
Score = 65.9 bits (159), Expect = 4e-10
Identities = 56/236 (23%), Positives = 89/236 (37%), Gaps = 36/236 (15%)
Query: 15 TSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
T+L+ + R ++ + P P N + E A+ E G P P V+W + QP++
Sbjct: 1868 TNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVS 1927
Query: 75 SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQP 134
S + R L I D G Y C A+N +G+ ++ L V
Sbjct: 1928 SWMGVTVSVDGR---VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVN---------- 1974
Query: 135 VVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
P + PS+ G P T + R +C TG P P + W
Sbjct: 1975 ----------VPPRITLPPSLPG--PVLVNTPV-----------RLTCNATGAPSPTLMW 2011
Query: 195 LKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
LK P+ P+ + G +VL + D G Y+C+ V+ G+ L +
Sbjct: 2012 LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 2067
Score = 63.2 bits (152), Expect = 2e-09
Identities = 50/197 (25%), Positives = 79/197 (40%), Gaps = 40/197 (20%)
Query: 59 YPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQ 116
+P P +TW ++G P + L + GT L I +ED G+YTC TN G +
Sbjct: 2568 FPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 2624
Query: 117 VTVELTVEGSFAKQ--LGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE 174
VE+ + S +K LG+ V + TK+ + E
Sbjct: 2625 YHVEVLIPPSISKDDPLGEVGVKEV------------------------KTKVNSTLTLE 2660
Query: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
C+ P P + W K P+ PS+R+ V + ++L+I D G Y C+
Sbjct: 2661 -------CESWAVPPPTIRWYKDGQPVTPSSRLQVLGEG--RLLQIQPTQVSDSGRYLCV 2711
Query: 235 VVNGSGKASMSAELSIQ 251
N +G+ + IQ
Sbjct: 2712 ATNVAGEDDQDFNVLIQ 2728
Score = 62.8 bits (151), Expect = 3e-09
Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 36/213 (16%)
Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
PP + + + A E G P P VTW R+GQP+ G L +G SL +
Sbjct: 2264 PPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV--GAELGLQLQNQGQ-SLHVERAQ 2320
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
G+Y+C A N +G + EL +V P + G
Sbjct: 2321 AAHTGRYSCVAENLAGRAERKFEL--------------------------SVLVPPELIG 2354
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+ P L + C+ G P P + W +G P+ P + G +
Sbjct: 2355 DLDP-----LTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLA--GGWM 2407
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
L++ + D G+Y+CL N +G+A + + +
Sbjct: 2408 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEV 2440
Score = 61.6 bits (148), Expect = 7e-09
Identities = 54/213 (25%), Positives = 85/213 (39%), Gaps = 42/213 (19%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIRG 87
+T+ P ++P N+ + G TA RV G +TW R+ + + S GR +
Sbjct: 513 VTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADL-- 570
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
SL I + D G+Y C A+N +G + +V L V + P VS + +
Sbjct: 571 --SLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREA-------PQVSIHTSSQHFSQ 621
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
VE + SC +G P P ++W + + LQ +R+
Sbjct: 622 GVEVK---------------------------VSCSASGYPTPHISWSRESQALQEDSRI 654
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
V + L I GV +D G Y+C N G
Sbjct: 655 HVDAQG---TLIIQGVAPEDAGNYSCQATNEVG 684
Score = 61.2 bits (147), Expect = 9e-09
Identities = 50/199 (25%), Positives = 80/199 (40%), Gaps = 34/199 (17%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+ +G TA V G+P+P++TW ++G+P+ G + G V+ A + G
Sbjct: 2457 VLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD--GVLLQVLQA-NLSSAGH 2513
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y+C A N G + +L+V L P + LG + E
Sbjct: 2514 YSCIAANAVGEKTKHFQLSV-------LLAPTI---LGGAEDSADEE------------- 2550
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
V V C+ P P +TW+K P + S + + G L+I
Sbjct: 2551 ------VTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNA 2602
Query: 224 NQDDVGVYTCLVVNGSGKA 242
++D G YTC+V N G+A
Sbjct: 2603 QKEDAGQYTCVVTNELGEA 2621
Score = 60.8 bits (146), Expect = 1e-08
Identities = 57/224 (25%), Positives = 80/224 (35%), Gaps = 44/224 (19%)
Query: 31 EAPAFILPPRNLCIKEGATAK---FEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
+AP I+ PR G E V P P++TWHR+G + RG
Sbjct: 3577 QAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFP--ERG 3634
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
F L + A+ D G Y+C A N +G+ V + + + P
Sbjct: 3635 RF-LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH--------------------TVP 3673
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SAR 206
+ + P V V Q C+ G P P V+W K VPL P S R
Sbjct: 3674 TIRSGPP--------------AVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPR 3719
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ + L I V D G Y CL N +G +L +
Sbjct: 3720 FEILPEGS---LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV 3760
Score = 60.5 bits (145), Expect = 2e-08
Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 9/153 (5%)
Query: 662 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
E + E+ HF++ G S I + GTY C A + AG R +A + V +P P
Sbjct: 464 EARLGEERHFQESGNS-SWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDP----PP 518
Query: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
+ P +VT S G++ ++SC + G+ + W+RD + L TG L + +L +
Sbjct: 519 QLVPAP-NVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLAD---LSLEI 574
Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
+ P G+Y+ + N G V L+++ +
Sbjct: 575 SGIIPTDGGRYQCVASNANGVTRASVWLLVREA 607
Score = 59.7 bits (143), Expect = 3e-08
Identities = 61/228 (26%), Positives = 82/228 (35%), Gaps = 46/228 (20%)
Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
T+ P+ + + G A G P P+V W+R G +L +
Sbjct: 695 TDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGL------EMILAPEGSSSG 748
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
L I A E D G YTC A N G ++L V
Sbjct: 749 KLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV-------------------------- 782
Query: 150 ETRPSIWGECPPKFATKLGR-VVVKEGQMGRFSCKITGRPQPQVTWLKGN-VPL---QPS 204
G P T+L R V V+ G+ +C+ TGRP P VTW +G+ PL +
Sbjct: 783 -------GHAPQ--LTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGA 833
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252
R S S + VL V +D Y C N GK A L + G
Sbjct: 834 GRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTG 881
Score = 57.4 bits (137), Expect = 1e-07
Identities = 64/279 (22%), Positives = 94/279 (33%), Gaps = 51/279 (18%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
+P K V +++LL C+ S P TI W G + T + G L
Sbjct: 3947 SPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQL---R 4003
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP----- 1211
I A PED G Y C+AKN AG A ++ V P EN + + LP
Sbjct: 4004 IAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARG 4063
Query: 1212 -------------PVLGTESDATVKK--------------------------KPAPKTPP 1232
PV G E T++ + +
Sbjct: 4064 SPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHL 4123
Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
+ P P D+ +R G+ + L G+ W + + E V + G
Sbjct: 4124 TILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGG 4179
Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
S L A +E G Y EN++G QA + V + P
Sbjct: 4180 STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 4218
Score = 56.2 bits (134), Expect = 3e-07
Identities = 53/195 (27%), Positives = 82/195 (42%), Gaps = 41/195 (21%)
Query: 56 VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
VRG P V+W ++G P+ R LL +L I V D G +TC A + +G
Sbjct: 3337 VRGSPPIHVSWLKDGLPLPLSQRTLLH---GSGHTLRISKVQLADAGIFTCVAASPAGV- 3392
Query: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
+ +F Q+ P P +E P +F VVV G
Sbjct: 3393 -------ADRNFTLQVQVP------------PVLE---------PVEFQND---VVVVRG 3421
Query: 176 QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
+ C+ G P P V+W+K PL +S S + G L++ V D G Y+C+
Sbjct: 3422 SLVELPCEARGVPLPLVSWMKDGEPL-----LSQSLEQGPS-LQLEAVGAGDSGTYSCVA 3475
Query: 236 VNGSGKASMSAELSI 250
V+ +G+A +L++
Sbjct: 3476 VSEAGEARRHFQLTV 3490
Score = 55.5 bits (132), Expect = 5e-07
Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 48/201 (23%)
Query: 57 RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQ 116
RG P P +TW ++G + + + + RG L + D G YTC+A+N GA +
Sbjct: 1527 RGVPTPNITWFKDGALLPTSTKVVYT---RGGRQLQLGRAQSSDAGVYTCKASNAVGAAE 1583
Query: 117 VTVEL------TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
L T+EG+ G+P V K + GR
Sbjct: 1584 KATRLDVYVPPTIEGAG----GRPYVVKAVA--------------------------GRP 1613
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
V E C G P P ++W +P+ S S E +G VL + + G+
Sbjct: 1614 VALE-------CVARGHPSPTLSWHHEGLPVAESNE-SRLETDG-SVLRLESPGEASSGL 1664
Query: 231 YTCLVVNGSGKASMSAELSIQ 251
Y+C+ + +G+A + + +Q
Sbjct: 1665 YSCVASSPAGEAVLQYSVEVQ 1685
Score = 54.7 bits (130), Expect = 8e-07
Identities = 55/220 (25%), Positives = 80/220 (36%), Gaps = 53/220 (24%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPI----------------TSGGRFLLDCGIRGTFS 90
G + E G+P P++ W ++ Q + GG LLD G S
Sbjct: 1315 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQ----S 1370
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + E D G Y+C A N +G Q L V
Sbjct: 1371 LHFPRIQEGDSGLYSCRAENQAGTAQRDFHL--------------------------LVL 1404
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
T PS+ G A V+ G C +G P PQV W K P+ P
Sbjct: 1405 TPPSVLG------AGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQV 1458
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+++G QVL I G + D G Y C+ + +G+ + +L +
Sbjct: 1459 QEDG-QVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRV 1497
Score = 54.7 bits (130), Expect = 8e-07
Identities = 61/259 (23%), Positives = 96/259 (37%), Gaps = 54/259 (20%)
Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQD----VHVAEGKKLLLQCQVSSDPPATIIWT 1132
C+ +A D + S PAF+Q + V V G K +L C+ + P T+ W
Sbjct: 3008 CEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 3067
Query: 1133 LNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
+G+ L + + G + I++A D+GLY C N AG+A + +TV P
Sbjct: 3068 KDGQPLVLAQRTQALRGGQ--RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPT 3125
Query: 1193 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1252
EN K TE+ + V AG
Sbjct: 3126 FENPK------------------TETVSQV----------------------------AG 3139
Query: 1253 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1312
+ L V+G T TW+K R ++ S V + G +L + + G YT +
Sbjct: 3140 SPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVS--RGGRLQLSRLQPAQAGTYTCVA 3197
Query: 1313 ENKLGSRQAQVNLTVVDKP 1331
EN + + V+ P
Sbjct: 3198 ENTQAEARKDFVVAVLVAP 3216
Score = 54.3 bits (129), Expect = 1e-06
Identities = 85/345 (24%), Positives = 123/345 (35%), Gaps = 83/345 (24%)
Query: 1076 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1135
+C+ + TD E + P+ V VA G++ +L C+ S PP +IW G
Sbjct: 676 SCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGG 735
Query: 1136 KTLKTTKFIILSQEGSLCS-VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--- 1191
+ IL+ EGS + I A D G Y C A N+ G A Q+ V AP
Sbjct: 736 LEM------ILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLT 789
Query: 1192 ----------------ASENTKAPE----------------------MKSRRPKSSLPPV 1213
A T P +SR+P S V
Sbjct: 790 ELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG---V 846
Query: 1214 LGTESDATVKKKP--------APKTPPKAAM------PPQIIQFPEDQKVRAGESVELFG 1259
L ES A + P K +A + PPQI +V G+ V L
Sbjct: 847 LFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPC 906
Query: 1260 KVTGTQPI-TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGS 1318
V +P+ W+K + + + +GS L + A QEH G Y+ + N GS
Sbjct: 907 IVLAGRPLPERHWLKDGRPLPPGSRHSIR--ADGS-LHLDRALQEHAGRYSCVATNTAGS 963
Query: 1319 RQAQVNLTV-------------VDKPDPPAGTPC-ASDIRSSSLT 1349
+ V L V + PA PC AS + + ++T
Sbjct: 964 QHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTIT 1008
Score = 53.9 bits (128), Expect = 1e-06
Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 8/119 (6%)
Query: 1721 SSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 1780
+ G+ T + E+ +D A L A P ++ S R+ V+EG R DC+
Sbjct: 3188 AQAGTYTCVAENTQAEARKDFVVAVLVA-----PRIRS--SGVAREHHVLEGQEVRLDCE 3240
Query: 1781 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
+G P P+V W KD + + + + DG SL++ + D YTC A N GE
Sbjct: 3241 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-SLVLKGLRASDAGAYTCVAHNPAGE 3298
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
+AP F+ + QD+ V G + L+CQ + +P TI W G+ L+ ++ + +GSL
Sbjct: 4307 SAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLE 4366
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
++E D G Y CVA N G A + V P
Sbjct: 4367 NVETG---DAGTYDCVAHNLLGSATARAFLVVRGEP 4399
Score = 53.5 bits (127), Expect = 2e-06
Identities = 67/282 (23%), Positives = 101/282 (35%), Gaps = 62/282 (21%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L V G+ L L CQ S P TI W NG+ + + ++ +G+ ++ I+ +
Sbjct: 1696 LGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT--TLHIDHVELD 1753
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD--------DAPASENTKAPEMKSRRPKSSLPP--- 1212
GL+ C A N+AG A +V+V + P + E S P + PP
Sbjct: 1754 HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 1813
Query: 1213 ----------VLGTESDATVKKKP-----APKTPP------------------------- 1232
V G S ++ +P A PP
Sbjct: 1814 GWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGE 1873
Query: 1233 -------KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
K +PP I P ++ V SV L +G P +W K + + S M
Sbjct: 1874 SKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMG 1931
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
V S +G L I A+ G Y + N GS + + L V
Sbjct: 1932 VTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRV 1973
Score = 53.5 bits (127), Expect = 2e-06
Identities = 65/285 (22%), Positives = 107/285 (37%), Gaps = 53/285 (18%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V V + L+C + PP T+ W +G+ + + L +G S+ +E+A G
Sbjct: 2268 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQ--SLHVERAQAAHTG 2325
Query: 1167 LYKCVAKNDAGQAECSCQVTV--------DDAPASENTKA----------------PEMK 1202
Y CVA+N AG+AE +++V D P + T A P ++
Sbjct: 2326 RYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 2385
Query: 1203 SRRPKSSLPPVLGT---------------ESDATVKKKPAPKTPPKA--------AMPPQ 1239
R + + P T E D+ + A +A +PP
Sbjct: 2386 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 2445
Query: 1240 I--IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1297
I E KV G++ L VTG TW K + + + + S +G L +
Sbjct: 2446 IENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHI--SPDGVLLQV 2503
Query: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
L A G Y+ + N +G + L+V+ P G ++D
Sbjct: 2504 LQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 2548
Score = 52.8 bits (125), Expect = 3e-06
Identities = 60/255 (23%), Positives = 91/255 (35%), Gaps = 54/255 (21%)
Query: 2 GDVKLVASSHISKTSLSVD-----PSRVDSMPLTEAPAFI-LPPRNLCIKEGATAKFEGR 55
G + VAS+ T L P R+ P P + P R C GA
Sbjct: 1952 GSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGA------- 2004
Query: 56 VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
P P + W ++G P++ G L G L + + D G+Y+C A + G
Sbjct: 2005 ----PSPTLMWLKDGNPVSPAGTPGLQV-FPGGRVLTLASARASDSGRYSCVAVSAVGED 2059
Query: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
+ V L V PSI GE +L VV
Sbjct: 2060 RQDVVLQVH--------------------------MPPSILGE-------ELNVSVVANE 2086
Query: 176 QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
+ C+ P P ++W K PL+P V +S + L++ + D G YTC
Sbjct: 2087 SVA-LECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEA 2143
Query: 236 VNGSGKASMSAELSI 250
+N +G + L++
Sbjct: 2144 LNQAGHSEKHYNLNV 2158
Score = 52.4 bits (124), Expect = 4e-06
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
V P + DL EGS A CK G P+P + W KD Q + + + + +
Sbjct: 4036 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGA---EGKFTIQPSGE 4092
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L++ ++ G D YTC A N++G A L +
Sbjct: 4093 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 4125
Score = 51.2 bits (121), Expect = 9e-06
Identities = 55/233 (23%), Positives = 89/233 (38%), Gaps = 41/233 (17%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
+++V L L+C+ + PP TI W +G+ + + + + EG L + I+
Sbjct: 2646 VKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL--LQIQPTQVS 2703
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP----ASENTKAPEMKSRRPKSSLPPVLGTESD 1219
D G Y CVA N AG+ + V + P + + A E+ SR ++ TE
Sbjct: 2704 DSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGV---TEYR 2760
Query: 1220 ATVKKKPA-PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
V+ PA A PP + + EDQ + AG+ V +
Sbjct: 2761 EIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVL-------------------- 2800
Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ G L I R E+ G Y+ N++G L V+ P
Sbjct: 2801 -----------QGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPP 2842
Score = 50.1 bits (118), Expect = 2e-05
Identities = 59/256 (23%), Positives = 96/256 (37%), Gaps = 56/256 (21%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ V +G+ L C V+ P + W +G+ L +S +G L V +A G
Sbjct: 2455 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVL--QANLSSAG 2512
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y C+A N G+ Q++V AP +LG D+
Sbjct: 2513 HYSCIAANAVGEKTKHFQLSVLLAPT--------------------ILGGAEDSA----- 2547
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
E+ V + L + TWMK + S ++++
Sbjct: 2548 -----------------DEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQL 2590
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP----DPPAGTPCASD 1342
+G L IL A++E G YT +V N+LG ++ V+ P D P G +
Sbjct: 2591 LPGTHG--LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKE 2648
Query: 1343 IR---SSSLTL---SW 1352
++ +S+LTL SW
Sbjct: 2649 VKTKVNSTLTLECESW 2664
Score = 49.7 bits (117), Expect = 3e-05
Identities = 43/208 (20%), Positives = 71/208 (34%), Gaps = 40/208 (19%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+ +T + G P P ++W +NG P + R + + L + D
Sbjct: 2857 VNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQV---LEDGQVLQVSTAEVADAAS 2913
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C A N +G+ + L V + PP+
Sbjct: 2914 YMCVAENQAGSAEKLFTLRV----------------------------------QVPPRI 2939
Query: 164 A-TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
A L +V C + P P+VTW K + L V + G L++
Sbjct: 2940 AGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLP--GTHTLQLGR 2997
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSI 250
D G+YTC +N +G+ +LS+
Sbjct: 2998 ARLSDSGMYTCEALNAAGRDQKLVQLSV 3025
Score = 49.7 bits (117), Expect = 3e-05
Identities = 52/234 (22%), Positives = 83/234 (35%), Gaps = 69/234 (29%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + L C V DP I W +G L+ + Q GSL +I + +D G Y+C+
Sbjct: 4233 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSL---TIHRTERDDAGRYQCL 4289
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A+N+ G A+ + + AP +
Sbjct: 4290 AENEMGVAKKVVILVLQSAPVFQVE----------------------------------- 4314
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK------ 1285
P+D VR+G+ V L + TG T W++ + ++ S ++
Sbjct: 4315 ------------PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS 4362
Query: 1286 --VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
+EN E G G Y + N LGS A+ L V +P G+
Sbjct: 4363 LWLENVETGD-----------AGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS 4405
Score = 49.3 bits (116), Expect = 4e-05
Identities = 60/269 (22%), Positives = 98/269 (36%), Gaps = 50/269 (18%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
+V V+ G+ +L C+V + P + W + + L + + +Q L S+ I +P D
Sbjct: 525 NVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRV-AQLADL-SLEISGIIPTDG 582
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAP---------------------ASENTKAPEMKSR 1204
G Y+CVA N G S + V +AP ++ P +
Sbjct: 583 GRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWS 642
Query: 1205 RPKSSLPPVLGTESDA---TVKKKPAPKTPPKAAM-------------------PPQIIQ 1242
R +L DA + + AP+ + PP +
Sbjct: 643 RESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSA 702
Query: 1243 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302
V GE L + +G P W + ++ + E S +G KL I AA++
Sbjct: 703 VNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEM----ILAPEGSSSG-KLRIPAAQE 757
Query: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
G YT N+LG A++ L V P
Sbjct: 758 RDAGTYTCRAVNELGDASAEIQLAVGHAP 786
Score = 49.3 bits (116), Expect = 4e-05
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 1741 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1800
V++A + + E P V + S +G + C GYP P + W ++ Q+++E
Sbjct: 595 VTRASVWLLVREAPQVSIHTSSQ----HFSQGVEVKVSCSASGYPTPHISWSRESQALQE 650
Query: 1801 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
+ D +LII V +D Y+C+A N +G
Sbjct: 651 DSRIHV----DAQGTLIIQGVAPEDAGNYSCQATNEVG 684
Score = 48.9 bits (115), Expect = 5e-05
Identities = 48/218 (22%), Positives = 78/218 (35%), Gaps = 44/218 (20%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
AP H ++G ++ + C S P I W+ + L+ I + +G+L
Sbjct: 607 APQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLI--- 663
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK-------SS 1209
I+ PED G Y C A N+ G + + + D P+ A + + + S
Sbjct: 664 IQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASG 723
Query: 1210 LPP------------VLGTESDATVKKK-PAPKTPPKAAM-------------------- 1236
+PP +L E ++ K + PA +
Sbjct: 724 VPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVG 783
Query: 1237 -PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
PQ+ + P D V G S L + TG P T TW +
Sbjct: 784 HAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRR 821
Score = 48.9 bits (115), Expect = 5e-05
Identities = 47/219 (21%), Positives = 77/219 (35%), Gaps = 48/219 (21%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V E + L+C S PP + W + + + + +S +G + + IE+A D G Y
Sbjct: 1897 VLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRV--LRIEQAQLSDAGSY 1954
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
+CVA N AG E + V+
Sbjct: 1955 RCVASNVAGSTELRYGLRVN---------------------------------------- 1974
Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
PP+ +PP + V V L TG T W+K + + ++
Sbjct: 1975 -VPPRITLPPSL-----PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQV 2028
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
G LT+ +AR G Y+ + + +G + V L V
Sbjct: 2029 FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 2067
Score = 48.5 bits (114), Expect = 6e-05
Identities = 49/220 (22%), Positives = 83/220 (37%), Gaps = 53/220 (24%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G+ + + C V PP + W +G L ++ +L GS ++ I K D G++ CV
Sbjct: 3328 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL--HGSGHTLRISKVQLADAGIFTCV 3385
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A + AG A+ + + V +PPVL
Sbjct: 3386 AASPAGVADRNFTLQV---------------------QVPPVL----------------- 3407
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
+ ++F D V G VEL + G +WMK + E + ++ E
Sbjct: 3408 -------EPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMK------DGEPLLSQSLEQ 3454
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
G L + A G Y+ + ++ G + LTV++ P
Sbjct: 3455 GPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPP 3494
Score = 47.0 bits (110), Expect = 2e-04
Identities = 60/228 (26%), Positives = 89/228 (39%), Gaps = 21/228 (9%)
Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAE---------TLKPMGNAKPDEN 1058
V P + P GP VG A L+ A+PA L+ + + E
Sbjct: 3574 VRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPER 3633
Query: 1059 LKSASKEELKKDVKNDVNCK-RGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLL 1117
+ + L D +C R AG+T R E T P + V+V+ + LL
Sbjct: 3634 GRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-TVPTIRSGPPAVNVSVNQTALL 3692
Query: 1118 QCQVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
CQ P + W + L ++ +F IL EGSL I+ L +D G Y C+A N
Sbjct: 3693 PCQADGVPAPLVSWRKDRVPLDPRSPRFEILP-EGSL---RIQPVLAQDAGHYLCLASNS 3748
Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
AG + V + PA AP + + P +L E+ + K
Sbjct: 3749 AGSDRQGRDLRVLEPPAI----APSPSNLTLTAHTPALLPCEASGSPK 3792
Score = 47.0 bits (110), Expect = 2e-04
Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F +D+ V G C+ G P P + W + Q +R SR + D SL
Sbjct: 4309 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG----SLW 4364
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 1854
+ +V D Y C A N LG AT A L+V +G
Sbjct: 4365 LENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQG 4401
Score = 46.2 bits (108), Expect = 3e-04
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 1768 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
E+VE + A C P P++ W+++DQ + + G L I V ++
Sbjct: 2761 EIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSV---LQGGRVLQIPLVRAENAG 2817
Query: 1828 KYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
+Y+CKA N +GE EL+V T G+ EE
Sbjct: 2818 RYSCKASNEVGEDWLHYELLVLTPPVILGDTEE 2850
Score = 44.3 bits (103), Expect = 0.001
Identities = 30/84 (35%), Positives = 40/84 (47%), Gaps = 6/84 (7%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ--IDYDEDGNCSLIISDVCGD 1824
LE V G A C G P P+V W K S E H Q + E+G SL ++ V
Sbjct: 1216 LERVAGENASLPCPARGTPKPQVTWRKGPSS--EPLHGQPGVAVLEEG--SLFLASVSPA 1271
Query: 1825 DDAKYTCKAVNSLGEATCTAELIV 1848
D Y C+A N +G + A+L+V
Sbjct: 1272 DSGDYECQATNEVGSTSRRAKLVV 1295
Score = 44.3 bits (103), Expect = 0.001
Identities = 60/271 (22%), Positives = 108/271 (39%), Gaps = 53/271 (19%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
+V V E + L C+ P I W +G L T+ ++ ++ G + + +A D
Sbjct: 1511 EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGR--QLQLGRAQSSDA 1568
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENT--------------KAPEMKSR-RPKSSL 1210
G+Y C A N G AE + ++ V P E A E +R P +L
Sbjct: 1569 GVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTL 1628
Query: 1211 P------PVLGT-----ESDATVKKKPAP------------KTPPKAA---------MPP 1238
PV + E+D +V + +P +P A +PP
Sbjct: 1629 SWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPP 1688
Query: 1239 QIIQFPEDQKVR--AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
Q++ +V G+ +EL + +G+ T W++ + +E ++V + G+ L
Sbjct: 1689 QLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQV--ASQGTTLH 1746
Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
I +H G + N+ G+ A+V ++V
Sbjct: 1747 IDHVELDHSGLFACQATNEAGTAGAEVEVSV 1777
Score = 44.3 bits (103), Expect = 0.001
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
DV V G + L C+ P + W +G+ L + ++G S+ +E D
Sbjct: 3415 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL----EQGP--SLQLEAVGAGDS 3468
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
G Y CVA ++AG+A Q+TV + P E++ P S P
Sbjct: 3469 GTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTP 3509
Score = 43.5 bits (101), Expect = 0.002
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
++ V+E + C+ G P P + WFKD + S ++ Y G L + D
Sbjct: 1511 EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTST--KVVYTRGGR-QLQLGRAQSSD 1567
Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1858
YTCKA N++G A L V EG G
Sbjct: 1568 AGVYTCKASNAVGAAEKATRLDVYVPPTIEGAG 1600
Score = 43.5 bits (101), Expect = 0.002
Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
++V++G A C + G+P P++ WFKD + + I D L +
Sbjct: 2455 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD---GVLLQVLQANLSSA 2511
Query: 1827 AKYTCKAVNSLGEAT---CTAELIVETMEEGEGEGEEEE 1862
Y+C A N++GE T + L+ T+ G + +EE
Sbjct: 2512 GHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE 2550
Score = 43.1 bits (100), Expect = 0.003
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
+V V + + L+CQ + PP + W +G+ L+ + LS + +L + +++A D
Sbjct: 2079 NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDA 2136
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAP 1191
G Y C A N AG +E + V AP
Sbjct: 2137 GHYTCEALNQAGHSEKHYNLNVWVAP 2162
Score = 43.1 bits (100), Expect = 0.003
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Query: 1101 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKA 1160
++ +++V V + LQC +P TI W NG + + + ++G + VS +
Sbjct: 2849 EELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 2908
Query: 1161 LPEDRGLYKCVAKNDAGQAE 1180
D Y CVA+N AG AE
Sbjct: 2909 --ADAASYMCVAENQAGSAE 2926
Score = 42.7 bits (99), Expect = 0.003
Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 7/97 (7%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
D+ VV GS C+ G P P V W KD + + + + SL + V D
Sbjct: 3415 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL-------LSQSLEQGPSLQLEAVGAGD 3467
Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
Y+C AV+ GEA +L V E G+ E
Sbjct: 3468 SGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTE 3504
Score = 42.4 bits (98), Expect = 0.004
Identities = 54/230 (23%), Positives = 83/230 (36%), Gaps = 22/230 (9%)
Query: 1111 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSVSIEKALPEDRGLYK 1169
EG L C S P TI WT L + +S+EG+L I + +D G Y
Sbjct: 989 EGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLL---IAQPSAQDAGAYV 1045
Query: 1170 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPK 1229
C A N G + +++V+ S+ E P SL D+ + A
Sbjct: 1046 CTATNTVGFSSQEMRLSVNRLALSKYVW--EEYGLLPSGSLRLAQVQVGDSGHYECTASN 1103
Query: 1230 TPPKAA--------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQES 1281
A+ +PPQ+ P KV GE+++L G +W K
Sbjct: 1104 PAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSK-------- 1155
Query: 1282 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ + ++ + A R G Y N G +V L V++ P
Sbjct: 1156 DGVVLQGRGPQGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPP 1205
Score = 42.0 bits (97), Expect = 0.006
Identities = 41/171 (23%), Positives = 68/171 (39%), Gaps = 26/171 (15%)
Query: 1689 MARRKWQKTG--------NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1740
+ R W K G +++RA G L + +GR S + T+ D
Sbjct: 914 LPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAG------SQHRD 967
Query: 1741 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1800
V E V + P + P + I + EG A C G P P + W K+ ++
Sbjct: 968 V-----ELVVQVPPRIHPTATHHITN----EGVPASLPCVASGVPAPTITWTKETNAL-T 1017
Query: 1801 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
SR + ++G +L+I+ D Y C A N++G ++ L V +
Sbjct: 1018 SRGPHYNVSKEG--TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRL 1066
Score = 42.0 bits (97), Expect = 0.006
Identities = 77/363 (21%), Positives = 129/363 (35%), Gaps = 71/363 (19%)
Query: 987 GKKKLPAENGSSSAETLNA-----KAVESS---KPLSNAQPSGPLKPV-GNAKPAETLKP 1037
G+ +L +++G + E LNA K V+ S P P GP V L
Sbjct: 2996 GRARL-SDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSC 3054
Query: 1038 MGNAKPAETL------KPMGNAKPDENLKSASKEELKKDVKND---VNCKRGHAGTTDNE 1088
+A P T+ +P+ A+ + L+ + E+++ +D +CK +
Sbjct: 3055 ETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR 3114
Query: 1089 KRSESQGTAPAFKQ-KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI-IL 1146
+ + P F+ K + V G L+L C VS P T+ W + ++++ ++
Sbjct: 3115 TFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVV 3174
Query: 1147 SQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
S+ G L + + P G Y CVA+N +A V V AP R
Sbjct: 3175 SRGGRL---QLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP-------------RI 3218
Query: 1207 KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQP 1266
+SS + V G+ V L + G P
Sbjct: 3219 RSS--------------------------------GVAREHHVLEGQEVRLDCEADGQPP 3246
Query: 1267 ITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVN 1324
W+K + + + +G L + R G YT + N G +R VN
Sbjct: 3247 PDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVN 3306
Query: 1325 LTV 1327
+ V
Sbjct: 3307 VLV 3309
Score = 42.0 bits (97), Expect = 0.006
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRES--RHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
G + + DC + G P P++ W KD +R S RH + N SL I DD +Y
Sbjct: 4233 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRH------QLQNGSLTIHRTERDDAGRY 4286
Query: 1830 TCKAVNSLGEATCTAELIVET 1850
C A N +G A L++++
Sbjct: 4287 QCLAENEMGVAKKVVILVLQS 4307
Score = 41.6 bits (96), Expect = 0.007
Identities = 31/99 (31%), Positives = 42/99 (42%), Gaps = 13/99 (13%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD--------QSIRESRHFQIDYD 1809
P ++ RD+ V G +A C+ G P P V W + D + R SR Q D
Sbjct: 786 PQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPD-- 843
Query: 1810 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+ L V +D A Y C+A N G+ A LIV
Sbjct: 844 ---SGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIV 879
Score = 41.6 bits (96), Expect = 0.007
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
C+ +P P + W KD SR+ Q+ G L I + +D +YTC N LG
Sbjct: 2563 CEALAFPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELG 2619
Query: 1839 EA 1840
EA
Sbjct: 2620 EA 2621
Score = 41.6 bits (96), Expect = 0.007
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
G A C+ + P+P V W+KD Q + ++ Q G L I + D Y+C
Sbjct: 3047 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQA---LRGGQRLEIQEAQVSDKGLYSC 3103
Query: 1832 KAVNSLGEATCTAELIVE 1849
K N GEA T L V+
Sbjct: 3104 KVSNVAGEAVRTFTLTVQ 3121
Score = 40.8 bits (94), Expect = 0.012
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 1766 DLEVVEG---SAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
DLE V S+ C + +P+PEV W+KD Q++ + G +L +
Sbjct: 2943 DLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV---FLLPGTHTLQLGRAR 2999
Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
D YTC+A+N+ G +L V
Sbjct: 3000 LSDSGMYTCEALNAAGRDQKLVQLSV 3025
Score = 40.4 bits (93), Expect = 0.016
Identities = 46/243 (18%), Positives = 84/243 (34%), Gaps = 53/243 (21%)
Query: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
+ E++G +++ + E L C ++ PP + W + L + + Q
Sbjct: 2748 REEEARGGVTEYRE------IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 2801
Query: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208
G + + + +A E+ G Y C A N+ G+ ++ V
Sbjct: 2802 GGRVLQIPLVRA--ENAGRYSCKASNEVGEDWLHYELLV--------------------- 2838
Query: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1268
PPV+ +++ V E+ V A +V L G T
Sbjct: 2839 LTPPVILGDTEELV----------------------EEVTVNASSTVSLQCPALGNPVPT 2876
Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
+W++ S ++V E+G L + A Y + EN+ GS + L V
Sbjct: 2877 ISWLQNGLPFSPSPRLQV--LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQ 2934
Query: 1329 DKP 1331
P
Sbjct: 2935 VPP 2937
Score = 39.3 bits (90), Expect = 0.036
Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 10/120 (8%)
Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1136
C ++ +D + R PA ++ + LL C+ S P ++W +G+
Sbjct: 3743 CLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQ 3802
Query: 1137 TLKTTKFIILSQEGSLCSVSIEKAL-----PEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
L Q+G+ + L P+D ++CV N+ G+A QVTV P
Sbjct: 3803 KLD-----FRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPP 3857
Score = 39.3 bits (90), Expect = 0.036
Identities = 65/278 (23%), Positives = 93/278 (33%), Gaps = 49/278 (17%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSVS 1156
P D V ++L C + P T+ W+ G L +S G+L
Sbjct: 3857 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL---E 3913
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP------------ASENTKAPEMKSR 1204
I +ALP G Y C A+N AG A +TV +P A E P S
Sbjct: 3914 IGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASG 3973
Query: 1205 RP-------KSSLPPVLGTESDA--------------------TVKKKPA----PKTPPK 1233
P K L G + + K A KT
Sbjct: 3974 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLV 4033
Query: 1234 AAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
+PP I D G L K G+ TW K + + +E K +G
Sbjct: 4034 VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEG-KFTIQPSG- 4091
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+L + + G YT EN +G + +V+LT++ P
Sbjct: 4092 ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLP 4129
Score = 38.5 bits (88), Expect = 0.062
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 10/82 (12%)
Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVCGDDD 1826
V G A C+ G P P V+W++ ++ +G+ S L I D
Sbjct: 709 VAVGEEAVLVCEASGVPPPRVIWYRGG--------LEMILAPEGSSSGKLRIPAAQERDA 760
Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
YTC+AVN LG+A+ +L V
Sbjct: 761 GTYTCRAVNELGDASAEIQLAV 782
Score = 38.5 bits (88), Expect = 0.062
Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 15/157 (9%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
++V V + L C+ + P I W +G + ++ I L + I A ED
Sbjct: 2549 EEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNAQKED 2606
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPA-SENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
G Y CV N+ G+A + V V P+ S++ E+ + K+ + L E ++
Sbjct: 2607 AGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESW-- 2664
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
A PP I + + Q V +++ G+
Sbjct: 2665 ----------AVPPPTIRWYKDGQPVTPSSRLQVLGE 2691
Score = 38.1 bits (87), Expect = 0.081
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 12/103 (11%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIR-----ESRHFQIDYDE-------DGNCSLIIS 1819
G + +C G+P PE+VW KD Q + + + + + D SL
Sbjct: 1315 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 1374
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
+ D Y+C+A N G A L+V T G G +E
Sbjct: 1375 RIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQE 1417
Score = 37.7 bits (86), Expect = 0.11
Identities = 33/132 (25%), Positives = 50/132 (37%), Gaps = 12/132 (9%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V G+ L L C +P + W+ +G ++L G SV D G Y
Sbjct: 1131 VLVGEALDLNCVAEGNPEPQLSWSKDG--------VVLQGRGPQGSVHFAAIRTSDAGRY 1182
Query: 1169 KCVAKNDAGQAECSCQVTVDDAP--ASENTKAPEMKSRRPKSSLP-PVLGTESDATVKKK 1225
+C A N AG ++ V + P ++ T + +SLP P GT +K
Sbjct: 1183 RCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKPQVTWRK 1242
Query: 1226 PAPKTPPKAAMP 1237
P + P P
Sbjct: 1243 -GPSSEPLHGQP 1253
Score = 37.7 bits (86), Expect = 0.11
Identities = 52/250 (20%), Positives = 85/250 (34%), Gaps = 45/250 (18%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
GD A + TS++ RV+ + P P + + TA + G P
Sbjct: 3648 GDYSCTARNAAGSTSVAF---RVE---IHTVPTIRSGPPAVNVSVNQTALLPCQADGVPA 3701
Query: 62 PQVTWHRNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P V+W ++ P+ RF I SL I V +D G Y C A+N +G+ + +
Sbjct: 3702 PLVSWRKDRVPLDPRSPRF----EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD 3757
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
L V PA+ PS + +
Sbjct: 3758 LRV--------------------LEPPAIAPSPS--------------NLTLTAHTPALL 3783
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
C+ +G P+P V W K L + L + D + C+V N G
Sbjct: 3784 PCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVG 3843
Query: 241 KASMSAELSI 250
+A ++++
Sbjct: 3844 EAHRLYQVTV 3853
Score = 37.7 bits (86), Expect = 0.11
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P + + +L + + A C+ G P P VVW+KD Q + + R Q Y + +L+
Sbjct: 3764 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL-DFRLQQGAYRLLPSNALL 3822
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEA 1840
++ D A++ C N +GEA
Sbjct: 3823 LTAPGPQDSAQFECVVSNEVGEA 3845
Score = 37.7 bits (86), Expect = 0.11
Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 13/132 (9%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F D + G +L L+C P I WT+N + + +S++ ++
Sbjct: 4129 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQR 4184
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT- 1216
ED G Y C A+N G+ + V V +AP + + + PV G+
Sbjct: 4185 AAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYL--------VEPVGGSI 4236
Query: 1217 ESDATVKKKPAP 1228
+ D V+ P P
Sbjct: 4237 QLDCVVRGDPVP 4248
Score = 37.0 bits (84), Expect = 0.18
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 9/93 (9%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
V P R L+V+ G A +C EG P+P++ W KD ++ S
Sbjct: 1118 VPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQ---------GRGPQGS 1168
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+ + + D +Y C+A NS G EL V
Sbjct: 1169 VHFAAIRTSDAGRYRCEASNSAGVDAWEVELRV 1201
Score = 37.0 bits (84), Expect = 0.18
Identities = 35/149 (23%), Positives = 56/149 (37%), Gaps = 8/149 (5%)
Query: 1694 WQKTG---NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVA 1750
W K G A R I L + L+ +K G T + E E+ ++ L +
Sbjct: 2575 WMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPS 2634
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
K P +++++ S +C+ P P + W+KD Q + S Q+ +
Sbjct: 2635 ISKDD--PLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGE- 2691
Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
L I D +Y C A N GE
Sbjct: 2692 --GRLLQIQPTQVSDSGRYLCVATNVAGE 2718
Score = 37.0 bits (84), Expect = 0.18
Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 8/105 (7%)
Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
W K G L S ++ G S + + G+ S + SE ++ + E
Sbjct: 3440 WMKDGEP------LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEP 3493
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1798
PH++ T +L + G+ C +G P P + W KD Q++
Sbjct: 3494 PHIEDSGQPT--ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL 3536
Score = 36.6 bits (83), Expect = 0.23
Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 4/92 (4%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRE-SRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
G+ C G P P+V W KD Q + H Q+ EDG I G D+ +Y
Sbjct: 1423 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQV--QEDGQVLRITGSHVG-DEGRYQ 1479
Query: 1831 CKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
C A + G+ +L V G E E
Sbjct: 1480 CVAFSPAGQQARDFQLRVHAPPTIWGSNETGE 1511
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
+ VV+ A +C G P P V W +D Q + Q+ ++ SL +
Sbjct: 2268 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQL---QNQGQSLHVERAQAAHT 2324
Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
+Y+C A N G A EL V
Sbjct: 2325 GRYSCVAENLAGRAERKFELSV 2346
Score = 36.6 bits (83), Expect = 0.23
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 3/74 (4%)
Query: 1778 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1837
+C +E P P++ W +D ++E H Q + E G L + + D Y+C A N+
Sbjct: 3602 ECSVEAEPAPKITWHRDGIVLQEDAHTQ--FPERGR-FLQLQALSTADSGDYSCTARNAA 3658
Query: 1838 GEATCTAELIVETM 1851
G + + + T+
Sbjct: 3659 GSTSVAFRVEIHTV 3672
Score = 36.6 bits (83), Expect = 0.23
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
V P F+ D + G C G P P + W +D+ + E ++DG +
Sbjct: 4127 VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS-----EQDGGST 4181
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
L + V +D Y C A N +G + + V+ +GE
Sbjct: 4182 LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 4223
Score = 36.2 bits (82), Expect = 0.31
Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
V+ + R C G P P ++W KD + + + G L ++ D +
Sbjct: 1989 VLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-LTLASARASDSGR 2047
Query: 1829 YTCKAVNSLGE 1839
Y+C AV+++GE
Sbjct: 2048 YSCVAVSAVGE 2058
Score = 35.8 bits (81), Expect = 0.40
Identities = 32/153 (20%), Positives = 55/153 (35%), Gaps = 19/153 (12%)
Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
W K GN V +G G + G L + + S + AV E++
Sbjct: 2011 WLKDGNPVSP----------AGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDR 2060
Query: 1754 P------HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
H+ P ++ VV + +C+ P P + W+KD + + +
Sbjct: 2061 QDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLS 2120
Query: 1808 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
D+ L + D YTC+A+N G +
Sbjct: 2121 ADK---ALLQVDRADVWDAGHYTCEALNQAGHS 2150
Score = 35.8 bits (81), Expect = 0.40
Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 5/100 (5%)
Query: 1236 MPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
+PPQI + P V L TG P T TW + + + ++++N G
Sbjct: 2254 VPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQ--G 2311
Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
L + A+ H G Y+ + EN G + + L+V+ P+
Sbjct: 2312 QSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPE 2351
Score = 35.4 bits (80), Expect = 0.52
Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 15/124 (12%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
++ + G + L C P I W +G+ L T+ S+ + V D
Sbjct: 3504 ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL--TRLENNSRATRVLRV-------RDA 3554
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
GLY C+A++ AG E S +V V P + P L VL + +V+ +
Sbjct: 3555 GLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL--VL----ECSVEAE 3608
Query: 1226 PAPK 1229
PAPK
Sbjct: 3609 PAPK 3612
Score = 34.7 bits (78), Expect = 0.89
Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 3/70 (4%)
Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
V+E ++ +C G P P+V WFK Q + S + DG L I D
Sbjct: 1897 VLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMGVTVSVDGRV-LRIEQAQLSDAGS 1953
Query: 1829 YTCKAVNSLG 1838
Y C A N G
Sbjct: 1954 YRCVASNVAG 1963
Score = 34.3 bits (77), Expect = 1.2
Identities = 59/265 (22%), Positives = 90/265 (33%), Gaps = 65/265 (24%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPE 1163
Q+V G + LQC S P + WT + + L + + ++G + ++
Sbjct: 1416 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV--G 1473
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y+CVA + AGQ Q+ V AP P + G+ V
Sbjct: 1474 DEGRYQCVAFSPAGQQARDFQLRV-HAP-------------------PTIWGSNETGEV- 1512
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
A M ++Q L + G TW K + S
Sbjct: 1513 ----------AVMEDHLVQ--------------LLCEARGVPTPNITWFKDGALLPTS-- 1546
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP------------ 1331
KV + G +L + A+ G YT N +G+ + L V P
Sbjct: 1547 TKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVV 1606
Query: 1332 DPPAGTPCASDIRS---SSLTLSWY 1353
AG P A + + S TLSW+
Sbjct: 1607 KAVAGRPVALECVARGHPSPTLSWH 1631
Score = 33.1 bits (74), Expect = 2.6
Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
C+ G P P + WF+ ++ + + Y G L ++ D Y+C A N G
Sbjct: 2374 CEAMGIPPPAIRWFRGEEPVSPG---EDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 2430
Query: 1839 EATCTAELIVETMEEGEGEGEEEEE 1863
EA VE + E E+ EE
Sbjct: 2431 EA--RRNFSVEVLVPPSIENEDLEE 2453
Score = 32.0 bits (71), Expect = 5.8
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 3/84 (3%)
Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
H P + V A C+ +G P P V W KD + + R + + +G
Sbjct: 3670 HTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPL-DPRSPRFEILPEG-- 3726
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
SL I V D Y C A NS G
Sbjct: 3727 SLRIQPVLAQDAGHYLCLASNSAG 3750
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 12/101 (11%)
Query: 1751 EEKPHVKPYFS--KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY 1808
+ P VKP S + + + EV+ C+ G P P + W K+ ++ Q+
Sbjct: 3945 QASPVVKPLPSVVRAVAEEEVL------LPCEASGIPRPTITWQKEGLNVATGVSTQVL- 3997
Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L I+ +D Y C A NS G A L+V+
Sbjct: 3998 ---PGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 4035
Score = 31.6 bits (70), Expect = 7.6
Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 5/83 (6%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTL--NGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169
G+ L C P + W + + L + + +EGSL S+ P D G Y+
Sbjct: 1221 GENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVS---PADSGDYE 1277
Query: 1170 CVAKNDAGQAECSCQVTVDDAPA 1192
C A N+ G ++ V P+
Sbjct: 1278 CQATNEVGSTSRRAKLVVYVPPS 1300
Score = 31.6 bits (70), Expect = 7.6
Identities = 27/130 (20%), Positives = 49/130 (37%), Gaps = 5/130 (3%)
Query: 1719 RKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFD 1778
R S G +S L + + +A L+ E + + ++ + + + G
Sbjct: 1653 RLESPGEASSGLYS--CVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELP 1710
Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
C+ G P P + W ++ + E Q+ +L I V D + C+A N G
Sbjct: 1711 CQASGSPVPTIQWLQNGRPAEELAGVQV---ASQGTTLHIDHVELDHSGLFACQATNEAG 1767
Query: 1839 EATCTAELIV 1848
A E+ V
Sbjct: 1768 TAGAEVEVSV 1777
Score = 31.6 bits (70), Expect = 7.6
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 3/71 (4%)
Query: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
V GS C + G P P V W KD + S + G L +S + Y
Sbjct: 3137 VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGV-VSRGGR--LQLSRLQPAQAGTY 3193
Query: 1830 TCKAVNSLGEA 1840
TC A N+ EA
Sbjct: 3194 TCVAENTQAEA 3204
Score = 31.2 bits (69), Expect = 9.9
Identities = 23/85 (27%), Positives = 33/85 (38%), Gaps = 3/85 (3%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+H + LL+ C V S P + L + QE S I +A + G
Sbjct: 436 IHGYLHQPLLVSCSVHSALPFRLQLRRGEARLGEERHF---QESGNSSWEILRASKAEEG 492
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191
Y+C A + AG Q+ V D P
Sbjct: 493 TYECTAVSRAGTGRAKAQIVVTDPP 517
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-D 1825
++ V G +C G+P P + W + + ES +++ D S++ + G+
Sbjct: 1606 VKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDG----SVLRLESPGEAS 1661
Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEE---GEGEGE 1859
Y+C A + GEA + V+ + EG G+
Sbjct: 1662 SGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQ 1698
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 1/93 (1%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
L V EG C+ G P P++ W KD Q + + + L + +
Sbjct: 2172 LTVREGHPTSLSCECRGVPFPKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQE 2230
Query: 1827 AKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1859
YTC+ N +G ++ +L V + G E
Sbjct: 2231 GTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 2263
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 171 bits (434), Expect = 5e-42
Identities = 181/790 (22%), Positives = 294/790 (37%), Gaps = 114/790 (14%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
P L + GA + +G P+P +TWH++GQ +T L+ R T L +
Sbjct: 2220 PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR-----LENNSRATRVLRVR---- 2270
Query: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
D G YTC A + +GA + K+ R AP P+I G
Sbjct: 2271 -DAGLYTCLAESPAGA---------------------IEKSFRVRVQAP-----PNIVGP 2303
Query: 159 CPPKFATKL--GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
P+F L G++V++ C + P P++TW + + LQ A E+ +
Sbjct: 2304 RGPRFVVGLAPGQLVLE--------CSVEAEPAPKITWHRDGIVLQEDAHTQFPERG--R 2353
Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD-----------SANRSFVRETK 265
L++ ++ D G Y+C N +G S++ + I + S N++ + +
Sbjct: 2354 FLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQ 2413
Query: 266 ATNSDV-----RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
A RK+ + + + + L + Q G A++ R+
Sbjct: 2414 ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQG 2473
Query: 321 KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPR--------APGLGVLSPSGEERK 372
+ + P AP L T+ + L P+ L G R
Sbjct: 2474 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 2533
Query: 373 RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVK 432
P+ T P Q + VVS + P V V
Sbjct: 2534 LPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVV 2593
Query: 433 FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNA 492
C +GIP P V+W G + + Y + S L + +A +G Y+C+A N+
Sbjct: 2594 LTCHSTGIPAPTVSWSKAGAQLGARGSG---YRVSPSGALEIGQALPIHAGRYTCSARNS 2650
Query: 493 QGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
G L V+ V++ PS + + ++ +L C G P P ITW G
Sbjct: 2651 AGVAHKHVFLTVQASPVVKPLPSVVRAVAE------EEVLLPCEASGIPRPTITWQKEGL 2704
Query: 553 PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL 612
+ ST +L I A PED G Y C+A+N+ G + V
Sbjct: 2705 NVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ----------- 2753
Query: 613 LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE-DFHF 671
P+ GL DL +GS + + G+P P + W +G + +E F
Sbjct: 2754 --------VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTI 2805
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 731
+ G L ++ + +D GTYTC A N+ G R + LT+ P F + P +
Sbjct: 2806 QPSG---ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL-----VLPVFTTLPGDRS 2857
Query: 732 ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 791
LG + + CA G P P + W + + + + V + + TL V +G
Sbjct: 2858 LRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSEQDGGSTLQRAAVSREDSGT 2912
Query: 792 YEILLKNRVG 801
Y +NRVG
Sbjct: 2913 YVCWAENRVG 2922
Score = 170 bits (430), Expect = 1e-41
Identities = 202/801 (25%), Positives = 298/801 (37%), Gaps = 150/801 (18%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
+ PS PL E + + K +T E P P + W+++GQP+T R
Sbjct: 1349 IPPSISKDDPLAEVGV-----KEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSR 1403
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ + L I D G+Y C ATN +G + ++ P + +
Sbjct: 1404 LQV---LGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ--------VPPMFQ 1452
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
+GD +A + +R E T+ +V E C P P +TW + +
Sbjct: 1453 KVGDFSAAFEILSRE----EEARGGVTEYREIV--ENNPAYLYCDTNAIPPPDLTWYRED 1506
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR 258
PL VSV + G +VL+I V ++ G Y+C N G+ + EL
Sbjct: 1507 QPLSAGDEVSVLQ--GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYEL---------- 1554
Query: 259 SFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP---WAANSQPQ 315
V D + V V S SL+ P G P W N P
Sbjct: 1555 -LVLTPPVILGDTEELVEEVTVNASSTVSLQC---------PALGNPVPTISWLQNGLPF 1604
Query: 316 PPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPA 375
P +P LQ LQ + + A + V ++
Sbjct: 1605 SP-----------------SPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLF 1647
Query: 376 PPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRC 435
R P R GL + V + N +V C
Sbjct: 1648 TLR-VQVPPRIAGLDLEQVTAIL-----------------------------NSSVSLPC 1677
Query: 436 EVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQ 495
+V P PEV W+ + + E EV+ G+H L L +AR DSG Y+C A NA G+
Sbjct: 1678 DVHAHPNPEVTWYKDSQALSLGE---EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGR 1734
Query: 496 LSCSWTLQVERLAVMEVAPSFSSVLK---DCAVIE-GQDFVLQCSVRGTPVPRITWLLNG 551
++ +L+V+ V P+F + D ++ G VL C P P +TW +G
Sbjct: 1735 -----DQKLVQLSVL-VPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDG 1788
Query: 552 QPIQYA-RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
QP+ A R+ G L IQ+A D G Y+C N G+ + +TV
Sbjct: 1789 QPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ--------- 1839
Query: 611 YLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH 670
+P P Q + GS + +T VSG P P V WL + ++ S
Sbjct: 1840 --VPPTFENPKTETVSQ-------VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHG 1890
Query: 671 FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSV 730
RG + L + + P GTYTC A N+ E R V+ V + PR
Sbjct: 1891 VVSRGGR--LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAV-----------LVAPRIR 1937
Query: 731 TASL--------GQSVLISCAIAGDPFPTVHWLRDGKALCKDTG-HFEVLQNEDVFTLVL 781
++ + GQ V + C G P P V WL+DG L +D G H D +LVL
Sbjct: 1938 SSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYL--DGGSLVL 1995
Query: 782 KKVQPWHAGQYEILLKNRVGE 802
K ++ AG Y + N GE
Sbjct: 1996 KGLRASDAGAYTCVAHNPAGE 2016
Score = 148 bits (374), Expect = 4e-35
Identities = 110/380 (28%), Positives = 176/380 (46%), Gaps = 44/380 (11%)
Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
C+ G P+P + W +G PV EG + S L + +D+GTY+CTA NA G
Sbjct: 2777 CKARGSPEPNITWDKDGQPVSGAEGKFTIQP---SGELLVKNLEGQDAGTYTCTAENAVG 2833
Query: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
+ L + V P F+++ D ++ G L+C+ RG+P PRI W +N +P+
Sbjct: 2834 RARRRVHLTIL------VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPV 2887
Query: 555 QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP 614
S + G + L ED GTY C AEN +G+ ++V V E
Sbjct: 2888 TEGVSEQDGG-STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKE------------ 2934
Query: 615 VAPSKPTAPIFLQG--LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 672
AP+ LQG S L G + + V G+P P++ W+ +G ++ S H
Sbjct: 2935 -------APV-LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQL 2986
Query: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTA 732
Q G SL I+ +D G Y C A N G + +L +Q + P F +P+ +T
Sbjct: 2987 QNG---SLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQ-----SAPVFQVEPQDMTV 3038
Query: 733 SLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
G V + C G+P PT+ WL+ G+ L + + L + +L L+ V+ AG Y
Sbjct: 3039 RSGDDVALRCQATGEPTPTIEWLQAGQPL-RASRRLRTLPDG---SLWLENVETGDAGTY 3094
Query: 793 EILLKNRVGECSCQVSLMLQ 812
+ + N +G + + L+++
Sbjct: 3095 DCVAHNLLGSATARAFLVVR 3114
Score = 146 bits (369), Expect = 2e-34
Identities = 120/405 (29%), Positives = 179/405 (44%), Gaps = 44/405 (10%)
Query: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
A P + P + V CE SGIP+P + W EG V + +
Sbjct: 2664 ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVST----QVLPGGQ 2719
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
L + A D+G Y C A N+ G L V++V P + L D + EG
Sbjct: 2720 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRL------VVQVPPVIENGLPDLSTTEGSHA 2773
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA-ELHIQDALPEDHGTYTCLAENALG 590
L C RG+P P ITW +GQP+ A + EL +++ +D GTYTC AENA+G
Sbjct: 2774 FLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG 2833
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
+ +T+ +LPV + P D + G ++ + G+P
Sbjct: 2834 RARRRVHLTI----------LVLPVFTTLP---------GDRSLRLGDRLWLRCAARGSP 2874
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
P + W N + E EQ G +L V ED+GTY C A N G RTQAV
Sbjct: 2875 TPRIGWTVNDRPVTEGVS---EQDGGS-TLQRAAVSREDSGTYVCWAENRVG--RTQAVS 2928
Query: 711 TVQEPHDGTQPWFISKPRS-VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
V H P + S + +G S+ + C + GDP P +HW++DG L + +
Sbjct: 2929 FV---HVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL-RGSHLRH 2984
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
LQN +L +++ + AG+Y+ L +N +G V L+LQ++
Sbjct: 2985 QLQNG---SLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSA 3026
Score = 138 bits (348), Expect = 4e-32
Identities = 185/745 (24%), Positives = 274/745 (36%), Gaps = 117/745 (15%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCG---IRG 87
E PA P NL + A G P+P V W ++GQ + F L G +
Sbjct: 2480 EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLD----FRLQQGAYRLLP 2535
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
+ +L++ A +D ++ C +N G ++TV
Sbjct: 2536 SNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH----------------------- 2572
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
P+I + T + VV+ +C TG P P V+W K L AR
Sbjct: 2573 ---VPPTIADDQTDFTVTMMAPVVL--------TCHSTGIPAPTVSWSKAGAQL--GARG 2619
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------LDSANRSFV 261
S + LEI G YTC N +G A L++Q L S R+
Sbjct: 2620 SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVA 2679
Query: 262 RETKATNSDV----------RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
E + +KE NV + S + + S G A N
Sbjct: 2680 EEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKN 2739
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA--ARVQPEPR------------ 357
S +++L + P P L T S AR PEP
Sbjct: 2740 SAGSAMGKTRLV-VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG 2798
Query: 358 APGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFE 417
A G + PSGE + + A T +++ V +A RR+ + P F
Sbjct: 2799 AEGKFTIQPSGELLVKNLEGQDAGTYT----CTAENAVGRA-RRRVHLT---ILVLPVFT 2850
Query: 418 SKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKA 477
+ P + ++ + RC G P P + W + PV EG V E G L
Sbjct: 2851 TLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVT--EG---VSEQDGGSTLQRAAV 2905
Query: 478 RTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
DSGTY C A N G+ + V+ V++ +FS +++ G L C V
Sbjct: 2906 SREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQ-GEAFSYLVEPV----GGSIQLDCVV 2960
Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
RG PVP I W+ +G P++ + + L I+ +D G Y CLAEN +G
Sbjct: 2961 RGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAENEMGVA----- 3015
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
K +L + +AP+F D+ V G V + Q +G P P + WL
Sbjct: 3016 ----------KKVVILVL----QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL 3061
Query: 658 HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ-EPH 716
G ++ S G SL ++ V D GTY C A N G +A L V+ EP
Sbjct: 3062 QAGQPLRASRRLRTLPDG---SLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3118
Query: 717 D--GTQPWFISKPRSVTASLGQSVL 739
G+ I+ + A+L SV+
Sbjct: 3119 GSWGSMTGVINGRKFGVATLNTSVM 3143
Score = 133 bits (335), Expect = 1e-30
Identities = 186/829 (22%), Positives = 285/829 (34%), Gaps = 196/829 (23%)
Query: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV 117
G P P + W +NG+P + +GT +L I V + G + C+ATN +G
Sbjct: 433 GSPVPTIQWLQNGRPAEELAG--VQVASQGT-TLHIDHVELDHSGLFACQATNEAGTAGA 489
Query: 118 TVELTVEGSFAK-----QLGQ----------------PVVSKTLGDRFSAPAVE---TRP 153
VE++V G +A +GQ P V + G P VE +
Sbjct: 490 EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPG 549
Query: 154 SIWGE-----------------------------------------------CPPKFATK 166
S+WGE PP
Sbjct: 550 SLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPG 609
Query: 167 LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226
V E C +G P P V+W KG+ P+ V+VS +VL I
Sbjct: 610 PVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLS 667
Query: 227 DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLD 286
D G Y C+ N +G + L + NV + +
Sbjct: 668 DAGSYRCVASNVAGSTELRYGLRV--------------------------NVPPRITLPP 701
Query: 287 SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSS-- 344
SL P +P + P + + +P + TP LQ
Sbjct: 702 SL---------PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV 752
Query: 345 ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPG--LGSQDVVSKAANRR 402
+TL +AR R + V S GE+R + P LG + VS AN
Sbjct: 753 LTLASARASDSGRYSCVAV-SAVGEDR------QDVVLQVHMPPSILGEELNVSVVANES 805
Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
+ +E Q + +P P ++W+ +G P+ + G
Sbjct: 806 VALECQSHA----------------------------MPPPVLSWWKDGRPLEPRPG--- 834
Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
V+ A L + +A D+G Y+C A N G + L V V + S + ++
Sbjct: 835 VHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVR- 893
Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHG 579
EG L C RG P P+I+W +GQP+ + + A L++ A G
Sbjct: 894 ----EGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 949
Query: 580 TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 639
TYTC N +G S + VH +P + P P + + V+
Sbjct: 950 TYTCECSNVVGNSSQDLQLEVH-----------VPPQIAGPREP-----PTQVSVVQDGV 993
Query: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
T+ +G PPP V W +G + + +G SL ++ TG Y+C A N
Sbjct: 994 ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG--QSLHVERAQAAHTGRYSCVAEN 1051
Query: 700 SAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
AG + L+V P + + ++TA+L + + C G P P + W R
Sbjct: 1052 LAGRAERKFELSVLVPPELIGD--LDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR--- 1106
Query: 760 ALCKDTGHFEVLQNEDVFTLV------LKKVQPWHAGQYEILLKNRVGE 802
G V ED + L + + Q +G Y L N GE
Sbjct: 1107 ------GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGE 1149
Score = 128 bits (322), Expect = 5e-29
Identities = 110/377 (29%), Positives = 156/377 (41%), Gaps = 44/377 (11%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V V+ CE G+P P V+W +G P+ Q E S L L DSGT
Sbjct: 2136 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQS-----LEQGPS--LQLEAVGAGDSGT 2188
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
YSC A + G+ + L V +E S + ++ G L C +GTP P
Sbjct: 2189 YSCVAVSEAGEARRHFQLTVMEPPHIED----SGQPTELSLTPGAPMELLCDAQGTPQPN 2244
Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
ITW +GQ + + A L ++DA G YTCLAE+ G + S V V
Sbjct: 2245 ITWHKDGQALTRLENNSRA-TRVLRVRDA-----GLYTCLAESPAGAIEKSFRVRVQA-- 2296
Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
P P P F+ GL+ Q+ + V P P++ W +G +Q
Sbjct: 2297 ---------PPNIVGPRGPRFVVGLAP------GQLVLECSVEAEPAPKITWHRDGIVLQ 2341
Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
E F +RG L +Q + D+G Y+C A N+AG + + T P
Sbjct: 2342 EDAHTQFPERG--RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-----TVPTIR 2394
Query: 725 SKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKV 784
S P +V S+ Q+ L+ C G P P V W +D L + FE+L +L ++ V
Sbjct: 2395 SGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPV 2451
Query: 785 QPWHAGQYEILLKNRVG 801
AG Y L N G
Sbjct: 2452 LAQDAGHYLCLASNSAG 2468
Score = 128 bits (321), Expect = 6e-29
Identities = 116/443 (26%), Positives = 177/443 (39%), Gaps = 43/443 (9%)
Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
V+ +C SG+P P+V W + PV ++V ED L + + D G Y C A
Sbjct: 144 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDG--QVLRITGSHVGDEGRYQCVAF 201
Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSF--SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 548
+ GQ + + L+V P+ S+ + AV+E L C RG P P ITW
Sbjct: 202 SPAGQQARDFQLRVH------APPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWF 255
Query: 549 LNGQPIQYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607
+G + + G +L + A D G YTC A NA+G +K++R
Sbjct: 256 KDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAA----------EKATR 305
Query: 608 KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
Y+ P P + K + G V + G+P P + W H G + ES
Sbjct: 306 LDVYVPPTIEGAGGRPYVV------KAVAGRPVALECVARGHPSPTLSWHHEGLPVAESN 359
Query: 668 DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP 727
+ E G+ L ++ +G Y+C A + AGE Q + VQ P Q
Sbjct: 360 ESRLETDGSV--LRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVP---PQLLVAEGL 414
Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 787
VT +GQ + + C +G P PT+ WL++G+ + G Q TL + V+
Sbjct: 415 GQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT---TLHIDHVELD 471
Query: 788 HAGQYEILLKNRVGECSCQVSLMLQNSSARA---LPRGREPASCEDLCGGGVGAD----- 839
H+G + N G +V + + A +P G+ E D
Sbjct: 472 HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 531
Query: 840 GGGSDRYGSLRPGWPARGQGWLE 862
G G+ L GW + G W E
Sbjct: 532 GWGAHPKPPLVEGWCSPGSLWGE 554
Score = 127 bits (318), Expect = 1e-28
Identities = 105/399 (26%), Positives = 167/399 (41%), Gaps = 47/399 (11%)
Query: 413 FPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472
FP ES + V+E + CE G+P P+++W +G P+ + ++ + A L
Sbjct: 882 FPLRES--HTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQ-HVSAVGRLL 938
Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE---RLAVMEVAPSFSSVLKDCAVIEGQ 529
L +A+ GTY+C SN G S L+V ++A P+ SV++D
Sbjct: 939 YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVA---- 994
Query: 530 DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV------AELHIQDALPEDHGTYTC 583
L+C+ G P P +TW +GQP+ E G+ LH++ A G Y+C
Sbjct: 995 --TLECNATGKPPPTVTWERDGQPV-----GAELGLQLQNQGQSLHVERAQAAHTGRYSC 1047
Query: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
+AEN G ++ RK E + V P L L+++ S +T+
Sbjct: 1048 VAENLAG-------------RAERKFELSVLVPPELIGD---LDPLTNITAALHSPLTLL 1091
Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
+ G PPP + W + ED + G L + + +D+G Y+C A N AGE
Sbjct: 1092 CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWM--LKMTQTQEQDSGLYSCLASNEAGE 1149
Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
R + V P + GQ+ + C + G P P + W +DG+ L +
Sbjct: 1150 ARRNFSVEVLVPPSIENE---DLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLAR 1206
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
H + D L + + AG Y + N VGE
Sbjct: 1207 GDAHH---ISPDGVLLQVLQANLSSAGHYSCIAANAVGE 1242
Score = 124 bits (311), Expect = 9e-28
Identities = 113/433 (26%), Positives = 165/433 (38%), Gaps = 53/433 (12%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P E P ++ V EN +V C SG+P P+V+WF PV G V L
Sbjct: 604 PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTVSVDGRVLR 660
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
+ +A+ D+G+Y C ASN G + L+V + + PS V+ L
Sbjct: 661 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPG-----PVLVNTPVRL 715
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
C+ G P P + WL +G P+ A + G L + A D G Y+C+A +A+G
Sbjct: 716 TCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVG 775
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
+ + VH P L ++ V+ V + Q P
Sbjct: 776 EDRQDVVLQVH-------------------MPPSILGEELNVSVVANESVALECQSHAMP 816
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
PP + W +G ++ H + L + D G YTCEA N AG
Sbjct: 817 PPVLSWWKDGRPLEPRPGVHLS--ADKALLQVDRADVWDAGHYTCEALNQAGH------- 867
Query: 711 TVQEPHDGTQPWF-----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
E H W + + ++T G +SC G PFP + W +DG+ L
Sbjct: 868 --SEKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPL---P 922
Query: 766 GHFEVLQNEDVF--TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGR 823
G LQ+ L L + Q G Y N VG S + L + A P R
Sbjct: 923 GEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGP--R 980
Query: 824 EPASCEDLCGGGV 836
EP + + GV
Sbjct: 981 EPPTQVSVVQDGV 993
Score = 119 bits (298), Expect = 3e-26
Identities = 109/396 (27%), Positives = 163/396 (41%), Gaps = 40/396 (10%)
Query: 423 QEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
+E+ EN C+ + IP P++ W+ E P+ + EV G L + R ++
Sbjct: 1478 REIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGD---EVSVLQGGRVLQIPLVRAENA 1534
Query: 483 GTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
G YSC ASN G+ + L V L + ++++ V LQC G PV
Sbjct: 1535 GRYSCKASNEVGEDWLHYELLV--LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPV 1592
Query: 543 PRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
P I+WL NG P + E G L + A D +Y C+AEN G
Sbjct: 1593 PTISWLQNGLPFSPSPRLQVLEDGQV-LQVSTAEVADAASYMCVAENQAG---------- 1641
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
+E L + P L L + + S V++ V +P PEV W +
Sbjct: 1642 -------SAEKLFTLRVQVPPRIAGLD-LEQVTAILNSSVSLPCDVHAHPNPEVTWYKDS 1693
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
+ E+ F GT H+L + D+G YTCEA N+AG + L+V P
Sbjct: 1694 QALSLGEEV-FLLPGT-HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP----- 1746
Query: 721 PWFISKPR----SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
P F PR +V +G ++SC P PTV W +DG+ L + L+
Sbjct: 1747 PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVL-AQRTQALRGGQ- 1804
Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
L +++ Q G Y + N GE +L +Q
Sbjct: 1805 -RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ 1839
Score = 119 bits (297), Expect = 4e-26
Identities = 99/385 (25%), Positives = 157/385 (40%), Gaps = 45/385 (11%)
Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
C V P P++ W +G + QE + + + G +L L T DSG YSCTA NA G
Sbjct: 2321 CSVEAEPAPKITWHRDGIVL--QEDAHTQFPERG-RFLQLQALSTADSGDYSCTARNAAG 2377
Query: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
S ++ +++ + + P +V + Q +L C G P P ++W + P+
Sbjct: 2378 STSVAFRVEIHTVPTIRSGPPAVNVSVN------QTALLPCQADGVPAPLVSWRKDRVPL 2431
Query: 555 QYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 613
E L IQ L +D G Y CLA N+ G S R+ L
Sbjct: 2432 DPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG--------------SDRQGRDLR 2477
Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673
+ P P S+L + + + + SG+P P V+W +G ++ DF +Q
Sbjct: 2478 VLEP-----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL----DFRLQQ 2528
Query: 674 RGTQ----HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729
+ ++L + P+D+ + C N GE +TV P P
Sbjct: 2529 GAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVP-----PTIADDQTD 2583
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
T ++ V+++C G P PTV W + G L + V + L + + P HA
Sbjct: 2584 FTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHA 2640
Query: 790 GQYEILLKNRVGECSCQVSLMLQNS 814
G+Y +N G V L +Q S
Sbjct: 2641 GRYTCSARNSAGVAHKHVFLTVQAS 2665
Score = 118 bits (296), Expect = 5e-26
Identities = 106/388 (27%), Positives = 155/388 (39%), Gaps = 48/388 (12%)
Query: 419 KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
+P + ++ C+ G P+P + W +G + R E + R
Sbjct: 2219 QPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR----------VLR 2268
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
RD+G Y+C A + G + S+ ++V+ + V P + A GQ VL+CSV
Sbjct: 2269 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLA--PGQ-LVLECSVE 2324
Query: 539 GTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
P P+ITW +G +Q A + L +Q D G Y+C A NA G S +
Sbjct: 2325 AEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFR 2384
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
V +H T P G + V + Q G P P V W
Sbjct: 2385 VEIH-------------------TVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWR 2425
Query: 658 HNGNEIQ-ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716
+ + S F G SL IQ V +D G Y C A NSAG R L V EP
Sbjct: 2426 KDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEP- 2481
Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL--CKDTGHFEVLQNE 774
P P ++T + L+ C +G P P V W +DG+ L G + +L +
Sbjct: 2482 ----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 2537
Query: 775 DVFTLVLKKVQPWHAGQYEILLKNRVGE 802
L+L P + Q+E ++ N VGE
Sbjct: 2538 ---ALLLTAPGPQDSAQFECVVSNEVGE 2562
Score = 117 bits (294), Expect = 8e-26
Identities = 108/407 (26%), Positives = 169/407 (41%), Gaps = 39/407 (9%)
Query: 414 PKFESKPQSQEVK--ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
P E++ + +K + QT C V+G P+P++ WF +G P+ R + +
Sbjct: 1162 PSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAH---HISPDGVL 1218
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
L +L+A +G YSC A+NA G+ + + L V LA + + S ++ V
Sbjct: 1219 LQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV-LLAPTILGGAEDSADEEVTVTVNNPI 1277
Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
L C P P ITW+ +G P + +R+ G L I +A ED G YTC+ N LG
Sbjct: 1278 SLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 1337
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
E + E L+P + SK P+ G+ ++K S +T+ + P
Sbjct: 1338 -----------EAVKNYHVEVLIPPSISKDD-PLAEVGVKEVKTKVNSTLTLECESWAVP 1385
Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE------V 704
PP + W +G + S + G L IQ D+G Y C A N AGE V
Sbjct: 1386 PPTIRWYKDGQPVTPSS--RLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNV 1443
Query: 705 RTQAVLTVQEPHDGTQPW-FISKPRSVTASL--------GQSVLISCAIAGDPFPTVHWL 755
Q Q+ D + + +S+ + + C P P + W
Sbjct: 1444 LIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWY 1503
Query: 756 RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
R+ + L VLQ V + L + + +AG+Y N VGE
Sbjct: 1504 REDQPLSAG-DEVSVLQGGRVLQIPLVRAE--NAGRYSCKASNEVGE 1547
Score = 117 bits (292), Expect = 1e-25
Identities = 105/406 (25%), Positives = 158/406 (38%), Gaps = 50/406 (12%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P S P + V NQT C+ G+P P V+W + P+ + E+ + L
Sbjct: 2391 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS---LR 2447
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
+ +D+G Y C ASN+ G L+V L +APS S++ + +L
Sbjct: 2448 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRV--LEPPAIAPSPSNL----TLTAHTPALL 2501
Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDAL------PEDHGTYTCLAEN 587
C G+P P + W +GQ + + + G L +AL P+D + C+ N
Sbjct: 2502 PCEASGSPKPLVVWWKDGQKLDF---RLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 2558
Query: 588 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
+G+ VTVH P +D V + V +T +
Sbjct: 2559 EVGEAHRLYQVTVH-------------------VPPTIADDQTDFTVTMMAPVVLTCHST 2599
Query: 648 GNPPPEVIWLHNGNEI-QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 706
G P P V W G ++ + G +L I + P G YTC A NSAG
Sbjct: 2600 GIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHAGRYTCSARNSAGVAHK 2656
Query: 707 QAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG 766
LTVQ P P V A + VL+ C +G P PT+ W ++G +
Sbjct: 2657 HVFLTVQ-----ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVS 2711
Query: 767 HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
+VL L + P AG Y + KN G + L++Q
Sbjct: 2712 -TQVLPGGQ---LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 2753
Score = 115 bits (289), Expect = 3e-25
Identities = 92/379 (24%), Positives = 158/379 (41%), Gaps = 42/379 (11%)
Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTY 485
+ + V C V G P V+W +G P+ + ++ H L + K + D+G +
Sbjct: 2044 RPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL---HGSGHTLRISKVQLADAGIF 2100
Query: 486 SCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRI 545
+C A++ G ++TLQV+ V+E D V+ G L C RG P+P +
Sbjct: 2101 TCVAASPAGVADRNFTLQVQVPPVLEPV----EFQNDVVVVRGSLVELPCEARGVPLPLV 2156
Query: 546 TWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
+W+ +G+P+ + E G L ++ D GTY+C+A + G+ +TV E
Sbjct: 2157 SWMKDGEPL--LSQSLEQG-PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 2213
Query: 606 SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
S +PT +L + G+ + + G P P + W +G +
Sbjct: 2214 IEDS--------GQPT---------ELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR 2256
Query: 666 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
E+ +S + + D G YTC A + AG + + VQ P + P
Sbjct: 2257 LEN---------NSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGP---R 2304
Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
PR V +++ C++ +P P + W RDG L +D H + + L L+ +
Sbjct: 2305 GPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQED-AHTQFPERGRF--LQLQALS 2361
Query: 786 PWHAGQYEILLKNRVGECS 804
+G Y +N G S
Sbjct: 2362 TADSGDYSCTARNAAGSTS 2380
Score = 114 bits (286), Expect = 7e-25
Identities = 105/389 (26%), Positives = 167/389 (42%), Gaps = 45/389 (11%)
Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
CE GIP P + WF PV E + Y AG L + + + +DSG YSC ASN G
Sbjct: 1092 CEAMGIPPPAIRWFRGEEPVSPGE---DTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 1148
Query: 495 QLSCSWTLQVERLAVMEVAPSFSS--VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
+ +++++V V PS + + + V++GQ L C+V G P P++TW +G+
Sbjct: 1149 EARRNFSVEV------LVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGR 1202
Query: 553 PIQY--ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
P+ A GV L + A G Y+C+A NA+G EK +
Sbjct: 1203 PLARGDAHHISPDGVL-LQVLQANLSSAGHYSCIAANAVG-----------EKTKHFQLS 1250
Query: 611 YLLPVAPSKPTAPIFLQGLSD-----LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
LL AP L G D + V + +++ + P P + W+ +G +
Sbjct: 1251 VLL--------APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEA 1302
Query: 666 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPH-DGTQPWF 723
S + GT H L I ED G YTC N GE V+ V + P P
Sbjct: 1303 SRNIQL-LPGT-HGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLA 1360
Query: 724 ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKK 783
+ V + ++ + C P PT+ W +DG+ + + +VL + L ++
Sbjct: 1361 EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPV-TPSSRLQVLGEGRL--LQIQP 1417
Query: 784 VQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
Q +G+Y + N GE ++++Q
Sbjct: 1418 TQVSDSGRYLCVATNVAGEDDQDFNVLIQ 1446
Score = 110 bits (274), Expect = 2e-23
Identities = 78/289 (26%), Positives = 125/289 (43%), Gaps = 26/289 (8%)
Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
V E+ V+ CE G+P P + WF +G + S +V G L L +A++ D+G
Sbjct: 232 VMEDHLVQLLCEARGVPTPNITWFKDGALLPT---STKVVYTRGGRQLQLGRAQSSDAGV 288
Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
Y+C ASNA G + L V +E A V+K + G+ L+C RG P P
Sbjct: 289 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVK---AVAGRPVALECVARGHPSPT 345
Query: 545 ITWLLNGQPIQYAR-STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
++W G P+ + S E + L ++ G Y+C+A + G+ V V
Sbjct: 346 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQV- 404
Query: 604 KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI 663
P + +GL + + G + + Q SG+P P + WL NG
Sbjct: 405 ----------------PPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPA 448
Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
+E +GT +L I V + +G + C+A N AG + ++V
Sbjct: 449 EELAGVQVASQGT--TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 495
Score = 106 bits (265), Expect = 2e-22
Identities = 123/519 (23%), Positives = 195/519 (37%), Gaps = 60/519 (11%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P E + + K N T+ CE +P P + W+ +G PV ++V + L
Sbjct: 1358 PLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVT-PSSRLQVLGEG--RLLQ 1414
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA--------- 524
+ + DSG Y C A+N G+ + + ++ + + FS+ + +
Sbjct: 1415 IQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGV 1474
Query: 525 -----VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPEDH 578
++E L C P P +TW QP+ + G L I E+
Sbjct: 1475 TEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENA 1534
Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL----QGLSDLKV 634
G Y+C A N +G+ W+ Y L V T P+ L + + ++ V
Sbjct: 1535 GRYSCKASNEVGE----DWL-----------HYELLVL----TPPVILGDTEELVEEVTV 1575
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
S V++ GNP P + WL NG S + G + EV D +Y
Sbjct: 1576 NASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV--ADAASYM 1633
Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753
C A N AG L VQ P P VTA L SV + C + P P V
Sbjct: 1634 CVAENQAGSAEKLFTLRVQVP-----PRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVT 1688
Query: 754 WLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL-MLQ 812
W +D +AL EV TL L + + +G Y N G V L +L
Sbjct: 1689 WYKDSQALSLGE---EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLV 1745
Query: 813 NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGV 872
+ R PRG + A + G +D W GQ + + + +RG
Sbjct: 1746 PPAFRQAPRGPQDAVLVRV--GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGG 1803
Query: 873 LKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLS 911
+ ++ Q +++ + +V ++ G+ V T TL+
Sbjct: 1804 QRLEIQEAQVSDKGLYSCKVS-----NVAGEAVRTFTLT 1837
Score = 98.6 bits (244), Expect = 5e-20
Identities = 100/403 (24%), Positives = 152/403 (37%), Gaps = 52/403 (12%)
Query: 429 QTVKFRCEVSGIPKPEVAWF----LEGTPVR----------RQEGSIEVYEDAGSHYLCL 474
Q++ C+ +G P PE+ W L G P+ Q G + ++ S L
Sbjct: 34 QSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQS--LHF 91
Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
+ + DSG YSC A N G + L V + A + VL + G D LQ
Sbjct: 92 PRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLG----LAGADVELQ 147
Query: 535 CSVRGTPVPRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
C G P P++ W + QP+ + L I + D G Y C+A + GQ
Sbjct: 148 CWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQ 207
Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG---LSDLKVMDGSQVTMTVQVSGN 649
+ + VH AP + G ++ VM+ V + + G
Sbjct: 208 ARDFQLRVH--------------------APPTIWGSNETGEVAVMEDHLVQLLCEARGV 247
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
P P + W +G + S + + G Q L + D G YTC+A N+ G
Sbjct: 248 PTPNITWFKDGALLPTSTKVVYTRGGRQ--LQLGRAQSSDAGVYTCKASNAVGAAEKATR 305
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
L V P T +P V A G+ V + C G P PT+ W +G + + E
Sbjct: 306 LDVYVP--PTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESN---E 360
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
D L L+ +G Y + + GE Q S+ +Q
Sbjct: 361 SRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 403
Score = 96.7 bits (239), Expect = 2e-19
Identities = 107/408 (26%), Positives = 149/408 (36%), Gaps = 33/408 (8%)
Query: 419 KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
+P + + V C G P P ++W EG PV E + E GS L L
Sbjct: 320 RPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVA--ESNESRLETDGS-VLRLESPG 376
Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
SG YSC AS+ G+ ++++V+ + VA V I GQ L C
Sbjct: 377 EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQV----TTIVGQPLELPCQAS 432
Query: 539 GTPVPRITWLLNGQPIQYARSTCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
G+PVP I WL NG+P + A LHI + G + C A N G
Sbjct: 433 GSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVE 492
Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPI-----FLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
V+VH + AP PI + S V PP
Sbjct: 493 VSVHGE-----------WAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPL 541
Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
W G+ E L I++V D G YTC A N AGE + + L V
Sbjct: 542 VEGWCSPGSLWGEPTGIPVAY-SLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKV 600
Query: 713 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
P +P ++K A SV + C +G P P V W + + + G V
Sbjct: 601 LVP-PNIEPGPVNKAVLENA----SVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTV 652
Query: 773 NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
+ D L +++ Q AG Y + N G + L + LP
Sbjct: 653 SVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLP 700
Score = 77.0 bits (188), Expect = 2e-13
Identities = 95/394 (24%), Positives = 136/394 (34%), Gaps = 60/394 (15%)
Query: 429 QTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCT 488
Q ++ C+ SG P P + W G P G + H + SG ++C
Sbjct: 423 QPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLH---IDHVELDHSGLFACQ 479
Query: 489 ASNAQGQLSCSWTLQVERLAVMEVAPSFSSV---LKDCAVIEGQDFVLQCS--------- 536
A+N G +VE E AP V F C
Sbjct: 480 ATNEAGTAGA----EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGA 535
Query: 537 ------VRGTPVPRITW-LLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
V G P W G P+ Y+ L I+ D G YTC A N
Sbjct: 536 HPKPPLVEGWCSPGSLWGEPTGIPVAYSLPP------PLQIEKVDLRDEGIYTCAATNLA 589
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
G+ S R+ + V P+ P+ + V++ + VT+ SG
Sbjct: 590 GE-------------SKREVALKVLVPPNIEPGPV------NKAVLENASVTLECLASGV 630
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
PPP+V W + G L I++ D G+Y C A N AG +
Sbjct: 631 PPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLSDAGSYRCVASNVAGSTELRYG 688
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC-KDTGHF 768
L V P T P + P V V ++C G P PT+ WL+DG + T
Sbjct: 689 LRVNVPPRITLPPSLPGPVLVNT----PVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGL 744
Query: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
+V V TL + +G+Y + + VGE
Sbjct: 745 QVFPGGRVLTLASARAS--DSGRYSCVAVSAVGE 776
Score = 72.8 bits (177), Expect = 3e-12
Identities = 74/290 (25%), Positives = 105/290 (36%), Gaps = 40/290 (13%)
Query: 528 GQDFVLQCSVRGTPVPRITWL----LNGQPIQYARSTCEAGVAE------------LHIQ 571
GQ L+C G PVP I WL L G P+ +A + G + LH
Sbjct: 33 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 92
Query: 572 DALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSD 631
D G Y+C AEN G ++++ +LL + P Q +
Sbjct: 93 RIQEGDSGLYSCRAENQAG--------------TAQRDFHLLVLTPPSVLGAGAAQEVLG 138
Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
L G+ V + SG P P+V W + + H + + L I D G
Sbjct: 139 LA---GADVELQCWTSGVPTPQVEWTKDRQPVLPGGP-HLQVQEDGQVLRITGSHVGDEG 194
Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
Y C A++ AG+ L V P W ++ V V + C G P P
Sbjct: 195 RYQCVAFSPAGQQARDFQLRVHAP---PTIWGSNETGEVAVMEDHLVQLLCEARGVPTPN 251
Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
+ W +DG L T +V+ L L + Q AG Y N VG
Sbjct: 252 ITWFKDGALLPTST---KVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVG 298
Score = 72.0 bits (175), Expect = 5e-12
Identities = 59/207 (28%), Positives = 83/207 (40%), Gaps = 42/207 (20%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLL---DCGIRGTFSLVIHAVHEEDRGK 103
GA + + G P PQV W ++ QP+ GG L D + L I H D G+
Sbjct: 141 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV-----LRITGSHVGDEGR 195
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C A + +G + +L V AP P+IWG
Sbjct: 196 YQCVAFSPAGQQARDFQLRVH---------------------AP-----PTIWG------ 223
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
+ + G V V E + + C+ G P P +TW K L S +V V + G Q L++
Sbjct: 224 SNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKV-VYTRGGRQ-LQLGRA 281
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSI 250
D GVYTC N G A + L +
Sbjct: 282 QSSDAGVYTCKASNAVGAAEKATRLDV 308
Score = 70.1 bits (170), Expect = 2e-11
Identities = 57/220 (25%), Positives = 85/220 (38%), Gaps = 35/220 (15%)
Query: 32 APAFIL-PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
AP F L L ++EG + RG P P+++W ++GQP+ G L G
Sbjct: 879 APVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL- 937
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + G YTCE +N G ++L V
Sbjct: 938 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQL--------------------------EVH 971
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
P I G P VV++G + C TG+P P VTW + P+ A + +
Sbjct: 972 VPPQIAGPREPPTQVS----VVQDG-VATLECNATGKPPPTVTWERDGQPV--GAELGLQ 1024
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+N Q L + G Y+C+ N +G+A ELS+
Sbjct: 1025 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSV 1064
Score = 68.2 bits (165), Expect = 7e-11
Identities = 57/238 (23%), Positives = 91/238 (38%), Gaps = 52/238 (21%)
Query: 16 SLSVDPSRVDSM-PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
S+ V P + + PLT A + P L + G P P + W R +P++
Sbjct: 1063 SVLVPPELIGDLDPLTNITAALHSPLTLLCE----------AMGIPPPAIRWFRGEEPVS 1112
Query: 75 SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLG 132
G L + G + L + E+D G Y+C A+N G R +VE+ V S +
Sbjct: 1113 PGEDTYL---LAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDL 1169
Query: 133 QPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192
+ V+ V +GQ C +TG PQP++
Sbjct: 1170 EEVIK----------------------------------VLDGQTAHLMCNVTGHPQPKL 1195
Query: 193 TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
TW K PL +S +L++ N G Y+C+ N G+ + +LS+
Sbjct: 1196 TWFKDGRPLARGDAHHISPDG--VLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 1251
Score = 67.4 bits (163), Expect = 1e-10
Identities = 58/214 (27%), Positives = 85/214 (39%), Gaps = 46/214 (21%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG----RFLLDCGIRGTFSLVIHAVHEE 99
+ EG + + G P P V W ++G P+ RF LD G SLV+ +
Sbjct: 1947 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-----SLVLKGLRAS 2001
Query: 100 DRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
D G YTC A N +G AR TV + V P+I
Sbjct: 2002 DAGAYTCVAHNPAGEDARLHTVNVLVP----------------------------PTI-- 2031
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+ A G +V + G++ C + G P V+WLK +PL S R +
Sbjct: 2032 ---KQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSG--HT 2086
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
L I V D G++TC+ + +G A + L +Q
Sbjct: 2087 LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 2120
Score = 65.9 bits (159), Expect = 4e-10
Identities = 56/236 (23%), Positives = 89/236 (37%), Gaps = 36/236 (15%)
Query: 15 TSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
T+L+ + R ++ + P P N + E A+ E G P P V+W + QP++
Sbjct: 586 TNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVS 645
Query: 75 SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQP 134
S + R L I D G Y C A+N +G+ ++ L V
Sbjct: 646 SWMGVTVSVDGR---VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVN---------- 692
Query: 135 VVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
P + PS+ G P T + R +C TG P P + W
Sbjct: 693 ----------VPPRITLPPSLPG--PVLVNTPV-----------RLTCNATGAPSPTLMW 729
Query: 195 LKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
LK P+ P+ + G +VL + D G Y+C+ V+ G+ L +
Sbjct: 730 LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 785
Score = 65.5 bits (158), Expect = 5e-10
Identities = 61/246 (24%), Positives = 92/246 (37%), Gaps = 48/246 (19%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
A + + +T +V V P+ + AF L G + + + VRG P P + W
Sbjct: 2917 AENRVGRTQ-AVSFVHVKEAPVLQGEAFSY----LVEPVGGSIQLDCVVRGDPVPDIHWI 2971
Query: 68 RNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
++G P+ R L G SL I +D G+Y C A N G + V L ++
Sbjct: 2972 KDGLPLRGSHLRHQLQNG-----SLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQ-- 3024
Query: 127 FAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186
SAP + P + V+ G C+ TG
Sbjct: 3025 ------------------SAPVFQVEPQ--------------DMTVRSGDDVALRCQATG 3052
Query: 187 RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
P P + WL+ PL+ S R+ L + V D G Y C+ N G A+ A
Sbjct: 3053 EPTPTIEWLQAGQPLRASRRLRTLPDGS---LWLENVETGDAGTYDCVAHNLLGSATARA 3109
Query: 247 ELSIQG 252
L ++G
Sbjct: 3110 FLVVRG 3115
Score = 62.8 bits (151), Expect = 3e-09
Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 36/213 (16%)
Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
PP + + + A E G P P VTW R+GQP+ G L +G SL +
Sbjct: 982 PPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV--GAELGLQLQNQGQ-SLHVERAQ 1038
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
G+Y+C A N +G + EL +V P + G
Sbjct: 1039 AAHTGRYSCVAENLAGRAERKFEL--------------------------SVLVPPELIG 1072
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+ P L + C+ G P P + W +G P+ P + G +
Sbjct: 1073 DLDP-----LTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLA--GGWM 1125
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
L++ + D G+Y+CL N +G+A + + +
Sbjct: 1126 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEV 1158
Score = 62.8 bits (151), Expect = 3e-09
Identities = 49/195 (25%), Positives = 79/195 (40%), Gaps = 36/195 (18%)
Query: 59 YPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQ 116
+P P +TW ++G P + L + GT L I +ED G+YTC TN G +
Sbjct: 1286 FPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 1342
Query: 117 VTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQ 176
VE+ + S +K D + V+ + TK+ + E
Sbjct: 1343 YHVEVLIPPSISKD-----------DPLAEVGVK-----------EVKTKVNSTLTLE-- 1378
Query: 177 MGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVV 236
C+ P P + W K P+ PS+R+ V + ++L+I D G Y C+
Sbjct: 1379 -----CESWAVPPPTIRWYKDGQPVTPSSRLQVLGEG--RLLQIQPTQVSDSGRYLCVAT 1431
Query: 237 NGSGKASMSAELSIQ 251
N +G+ + IQ
Sbjct: 1432 NVAGEDDQDFNVLIQ 1446
Score = 61.2 bits (147), Expect = 9e-09
Identities = 50/199 (25%), Positives = 80/199 (40%), Gaps = 34/199 (17%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+ +G TA V G+P+P++TW ++G+P+ G + G V+ A + G
Sbjct: 1175 VLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD--GVLLQVLQA-NLSSAGH 1231
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y+C A N G + +L+V L P + LG + E
Sbjct: 1232 YSCIAANAVGEKTKHFQLSV-------LLAPTI---LGGAEDSADEE------------- 1268
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
V V C+ P P +TW+K P + S + + G L+I
Sbjct: 1269 ------VTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNA 1320
Query: 224 NQDDVGVYTCLVVNGSGKA 242
++D G YTC+V N G+A
Sbjct: 1321 QKEDAGQYTCVVTNELGEA 1339
Score = 60.8 bits (146), Expect = 1e-08
Identities = 57/224 (25%), Positives = 80/224 (35%), Gaps = 44/224 (19%)
Query: 31 EAPAFILPPRNLCIKEGATAK---FEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
+AP I+ PR G E V P P++TWHR+G + RG
Sbjct: 2295 QAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFP--ERG 2352
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
F L + A+ D G Y+C A N +G+ V + + + P
Sbjct: 2353 RF-LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH--------------------TVP 2391
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SAR 206
+ + P V V Q C+ G P P V+W K VPL P S R
Sbjct: 2392 TIRSGPP--------------AVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPR 2437
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ + L I V D G Y CL N +G +L +
Sbjct: 2438 FEILPEGS---LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV 2478
Score = 57.4 bits (137), Expect = 1e-07
Identities = 64/279 (22%), Positives = 94/279 (33%), Gaps = 51/279 (18%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
+P K V +++LL C+ S P TI W G + T + G L
Sbjct: 2665 SPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQL---R 2721
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP----- 1211
I A PED G Y C+AKN AG A ++ V P EN + + LP
Sbjct: 2722 IAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARG 2781
Query: 1212 -------------PVLGTESDATVKK--------------------------KPAPKTPP 1232
PV G E T++ + +
Sbjct: 2782 SPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHL 2841
Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
+ P P D+ +R G+ + L G+ W + + E V + G
Sbjct: 2842 TILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGG 2897
Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
S L A +E G Y EN++G QA + V + P
Sbjct: 2898 STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 2936
Score = 56.2 bits (134), Expect = 3e-07
Identities = 53/195 (27%), Positives = 82/195 (42%), Gaps = 41/195 (21%)
Query: 56 VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
VRG P V+W ++G P+ R LL +L I V D G +TC A + +G
Sbjct: 2055 VRGSPPIHVSWLKDGLPLPLSQRTLLH---GSGHTLRISKVQLADAGIFTCVAASPAGV- 2110
Query: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
+ +F Q+ P P +E P +F VVV G
Sbjct: 2111 -------ADRNFTLQVQVP------------PVLE---------PVEFQND---VVVVRG 2139
Query: 176 QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
+ C+ G P P V+W+K PL +S S + G L++ V D G Y+C+
Sbjct: 2140 SLVELPCEARGVPLPLVSWMKDGEPL-----LSQSLEQGPS-LQLEAVGAGDSGTYSCVA 2193
Query: 236 VNGSGKASMSAELSI 250
V+ +G+A +L++
Sbjct: 2194 VSEAGEARRHFQLTV 2208
Score = 55.5 bits (132), Expect = 5e-07
Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 48/201 (23%)
Query: 57 RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQ 116
RG P P +TW ++G + + + + RG L + D G YTC+A+N GA +
Sbjct: 245 RGVPTPNITWFKDGALLPTSTKVVYT---RGGRQLQLGRAQSSDAGVYTCKASNAVGAAE 301
Query: 117 VTVEL------TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
L T+EG+ G+P V K + GR
Sbjct: 302 KATRLDVYVPPTIEGAG----GRPYVVKAVA--------------------------GRP 331
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
V E C G P P ++W +P+ S S E +G VL + + G+
Sbjct: 332 VALE-------CVARGHPSPTLSWHHEGLPVAESNE-SRLETDG-SVLRLESPGEASSGL 382
Query: 231 YTCLVVNGSGKASMSAELSIQ 251
Y+C+ + +G+A + + +Q
Sbjct: 383 YSCVASSPAGEAVLQYSVEVQ 403
Score = 54.7 bits (130), Expect = 8e-07
Identities = 55/220 (25%), Positives = 80/220 (36%), Gaps = 53/220 (24%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPI----------------TSGGRFLLDCGIRGTFS 90
G + E G+P P++ W ++ Q + GG LLD G S
Sbjct: 33 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQ----S 88
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + E D G Y+C A N +G Q L V
Sbjct: 89 LHFPRIQEGDSGLYSCRAENQAGTAQRDFHL--------------------------LVL 122
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
T PS+ G A V+ G C +G P PQV W K P+ P
Sbjct: 123 TPPSVLG------AGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQV 176
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+++G QVL I G + D G Y C+ + +G+ + +L +
Sbjct: 177 QEDG-QVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRV 215
Score = 54.7 bits (130), Expect = 8e-07
Identities = 61/259 (23%), Positives = 96/259 (37%), Gaps = 54/259 (20%)
Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQD----VHVAEGKKLLLQCQVSSDPPATIIWT 1132
C+ +A D + S PAF+Q + V V G K +L C+ + P T+ W
Sbjct: 1726 CEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 1785
Query: 1133 LNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
+G+ L + + G + I++A D+GLY C N AG+A + +TV P
Sbjct: 1786 KDGQPLVLAQRTQALRGGQ--RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPT 1843
Query: 1193 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1252
EN K TE+ + V AG
Sbjct: 1844 FENPK------------------TETVSQV----------------------------AG 1857
Query: 1253 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1312
+ L V+G T TW+K R ++ S V + G +L + + G YT +
Sbjct: 1858 SPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVS--RGGRLQLSRLQPAQAGTYTCVA 1915
Query: 1313 ENKLGSRQAQVNLTVVDKP 1331
EN + + V+ P
Sbjct: 1916 ENTQAEARKDFVVAVLVAP 1934
Score = 53.9 bits (128), Expect = 1e-06
Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 8/119 (6%)
Query: 1721 SSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 1780
+ G+ T + E+ +D A L A P ++ S R+ V+EG R DC+
Sbjct: 1906 AQAGTYTCVAENTQAEARKDFVVAVLVA-----PRIRS--SGVAREHHVLEGQEVRLDCE 1958
Query: 1781 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
+G P P+V W KD + + + + DG SL++ + D YTC A N GE
Sbjct: 1959 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-SLVLKGLRASDAGAYTCVAHNPAGE 2016
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
+AP F+ + QD+ V G + L+CQ + +P TI W G+ L+ ++ + +GSL
Sbjct: 3025 SAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLE 3084
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
++E D G Y CVA N G A + V P
Sbjct: 3085 NVETG---DAGTYDCVAHNLLGSATARAFLVVRGEP 3117
Score = 53.5 bits (127), Expect = 2e-06
Identities = 67/282 (23%), Positives = 101/282 (35%), Gaps = 62/282 (21%)
Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
L V G+ L L CQ S P TI W NG+ + + ++ +G+ ++ I+ +
Sbjct: 414 LGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT--TLHIDHVELD 471
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD--------DAPASENTKAPEMKSRRPKSSLPP--- 1212
GL+ C A N+AG A +V+V + P + E S P + PP
Sbjct: 472 HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 531
Query: 1213 ----------VLGTESDATVKKKP-----APKTPP------------------------- 1232
V G S ++ +P A PP
Sbjct: 532 GWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGE 591
Query: 1233 -------KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
K +PP I P ++ V SV L +G P +W K + + S M
Sbjct: 592 SKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMG 649
Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
V S +G L I A+ G Y + N GS + + L V
Sbjct: 650 VTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRV 691
Score = 53.5 bits (127), Expect = 2e-06
Identities = 65/285 (22%), Positives = 107/285 (37%), Gaps = 53/285 (18%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
V V + L+C + PP T+ W +G+ + + L +G S+ +E+A G
Sbjct: 986 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQ--SLHVERAQAAHTG 1043
Query: 1167 LYKCVAKNDAGQAECSCQVTV--------DDAPASENTKA----------------PEMK 1202
Y CVA+N AG+AE +++V D P + T A P ++
Sbjct: 1044 RYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 1103
Query: 1203 SRRPKSSLPPVLGT---------------ESDATVKKKPAPKTPPKA--------AMPPQ 1239
R + + P T E D+ + A +A +PP
Sbjct: 1104 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 1163
Query: 1240 I--IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1297
I E KV G++ L VTG TW K + + + + S +G L +
Sbjct: 1164 IENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHI--SPDGVLLQV 1221
Query: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
L A G Y+ + N +G + L+V+ P G ++D
Sbjct: 1222 LQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 1266
Score = 52.8 bits (125), Expect = 3e-06
Identities = 60/255 (23%), Positives = 91/255 (35%), Gaps = 54/255 (21%)
Query: 2 GDVKLVASSHISKTSLSVD-----PSRVDSMPLTEAPAFI-LPPRNLCIKEGATAKFEGR 55
G + VAS+ T L P R+ P P + P R C GA
Sbjct: 670 GSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGA------- 722
Query: 56 VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
P P + W ++G P++ G L G L + + D G+Y+C A + G
Sbjct: 723 ----PSPTLMWLKDGNPVSPAGTPGLQV-FPGGRVLTLASARASDSGRYSCVAVSAVGED 777
Query: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
+ V L V PSI GE +L VV
Sbjct: 778 RQDVVLQVH--------------------------MPPSILGE-------ELNVSVVANE 804
Query: 176 QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
+ C+ P P ++W K PL+P V +S + L++ + D G YTC
Sbjct: 805 SVA-LECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEA 861
Query: 236 VNGSGKASMSAELSI 250
+N +G + L++
Sbjct: 862 LNQAGHSEKHYNLNV 876
Score = 52.4 bits (124), Expect = 4e-06
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
V P + DL EGS A CK G P+P + W KD Q + + + + +
Sbjct: 2754 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGA---EGKFTIQPSGE 2810
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L++ ++ G D YTC A N++G A L +
Sbjct: 2811 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 2843
Score = 51.6 bits (122), Expect = 7e-06
Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 41/239 (17%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P + +++V L L+C+ + PP TI W +G+ + + + + EG L + I
Sbjct: 1358 PLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL--LQI 1415
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP----ASENTKAPEMKSRRPKSSLPPV 1213
+ D G Y CVA N AG+ + V + P + + A E+ SR ++
Sbjct: 1416 QPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGV- 1474
Query: 1214 LGTESDATVKKKPA-PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
TE V+ PA A PP + + EDQ + AG+ V +
Sbjct: 1475 --TEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVL-------------- 1518
Query: 1273 KFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+ G L I R E+ G Y+ N++G L V+ P
Sbjct: 1519 -----------------QGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPP 1560
Score = 49.7 bits (117), Expect = 3e-05
Identities = 52/234 (22%), Positives = 83/234 (35%), Gaps = 69/234 (29%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G + L C V DP I W +G L+ + Q GSL +I + +D G Y+C+
Sbjct: 2951 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSL---TIRRTERDDAGRYQCL 3007
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A+N+ G A+ + + AP +
Sbjct: 3008 AENEMGVAKKVVILVLQSAPVFQVE----------------------------------- 3032
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK------ 1285
P+D VR+G+ V L + TG T W++ + ++ S ++
Sbjct: 3033 ------------PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS 3080
Query: 1286 --VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
+EN E G G Y + N LGS A+ L V +P G+
Sbjct: 3081 LWLENVETGD-----------AGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS 3123
Score = 48.9 bits (115), Expect = 5e-05
Identities = 47/219 (21%), Positives = 77/219 (35%), Gaps = 48/219 (21%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
V E + L+C S PP + W + + + + +S +G + + IE+A D G Y
Sbjct: 615 VLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRV--LRIEQAQLSDAGSY 672
Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
+CVA N AG E + V+
Sbjct: 673 RCVASNVAGSTELRYGLRVN---------------------------------------- 692
Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
PP+ +PP + V V L TG T W+K + + ++
Sbjct: 693 -VPPRITLPPSL-----PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQV 746
Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
G LT+ +AR G Y+ + + +G + V L V
Sbjct: 747 FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 785
Score = 48.5 bits (114), Expect = 6e-05
Identities = 49/220 (22%), Positives = 83/220 (37%), Gaps = 53/220 (24%)
Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
G+ + + C V PP + W +G L ++ +L GS ++ I K D G++ CV
Sbjct: 2046 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL--HGSGHTLRISKVQLADAGIFTCV 2103
Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
A + AG A+ + + V +PPVL
Sbjct: 2104 AASPAGVADRNFTLQV---------------------QVPPVL----------------- 2125
Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
+ ++F D V G VEL + G +WMK + E + ++ E
Sbjct: 2126 -------EPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMK------DGEPLLSQSLEQ 2172
Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
G L + A G Y+ + ++ G + LTV++ P
Sbjct: 2173 GPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPP 2212
Score = 48.1 bits (113), Expect = 8e-05
Identities = 42/181 (23%), Positives = 69/181 (38%), Gaps = 18/181 (9%)
Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI-------QESEDFHFEQRGTQ------HSLC 681
M G +T+ +G P PE++WL + + D + Q G SL
Sbjct: 31 MAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLH 90
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
+ D+G Y+C A N AG + L V P + V G V +
Sbjct: 91 FPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTP---PSVLGAGAAQEVLGLAGADVELQ 147
Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
C +G P P V W +D + + H +V ++ V + V G+Y+ + + G
Sbjct: 148 CWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV--GDEGRYQCVAFSPAG 205
Query: 802 E 802
+
Sbjct: 206 Q 206
Score = 47.8 bits (112), Expect = 1e-04
Identities = 52/234 (22%), Positives = 84/234 (35%), Gaps = 46/234 (19%)
Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
+ V +G+ L C V+ P + W +G+ L +S +G L V +A G
Sbjct: 1173 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVL--QANLSSAG 1230
Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
Y C+A N G+ Q++V AP +LG D+
Sbjct: 1231 HYSCIAANAVGEKTKHFQLSVLLAPT--------------------ILGGAEDSA----- 1265
Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
E+ V + L + TWMK + S ++++
Sbjct: 1266 -----------------DEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQL 1308
Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCA 1340
+G L IL A++E G YT +V N+LG ++ V+ P P A
Sbjct: 1309 LPGTHG--LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLA 1360
Score = 47.0 bits (110), Expect = 2e-04
Identities = 60/228 (26%), Positives = 89/228 (39%), Gaps = 21/228 (9%)
Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAE---------TLKPMGNAKPDEN 1058
V P + P GP VG A L+ A+PA L+ + + E
Sbjct: 2292 VRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPER 2351
Query: 1059 LKSASKEELKKDVKNDVNCK-RGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLL 1117
+ + L D +C R AG+T R E T P + V+V+ + LL
Sbjct: 2352 GRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-TVPTIRSGPPAVNVSVNQTALL 2410
Query: 1118 QCQVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
CQ P + W + L ++ +F IL EGSL I+ L +D G Y C+A N
Sbjct: 2411 PCQADGVPAPLVSWRKDRVPLDPRSPRFEILP-EGSL---RIQPVLAQDAGHYLCLASNS 2466
Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
AG + V + PA AP + + P +L E+ + K
Sbjct: 2467 AGSDRQGRDLRVLEPPAI----APSPSNLTLTAHTPALLPCEASGSPK 2510
Score = 47.0 bits (110), Expect = 2e-04
Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F +D+ V G C+ G P P + W + Q +R SR + D SL
Sbjct: 3027 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG----SLW 3082
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 1854
+ +V D Y C A N LG AT A L+V +G
Sbjct: 3083 LENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQG 3119
Score = 46.2 bits (108), Expect = 3e-04
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 1768 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
E+VE + A C P P++ W+++DQ + + G L I V ++
Sbjct: 1479 EIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSV---LQGGRVLQIPLVRAENAG 1535
Query: 1828 KYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
+Y+CKA N +GE EL+V T G+ EE
Sbjct: 1536 RYSCKASNEVGEDWLHYELLVLTPPVILGDTEE 1568
Score = 44.3 bits (103), Expect = 0.001
Identities = 60/271 (22%), Positives = 108/271 (39%), Gaps = 53/271 (19%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
+V V E + L C+ P I W +G L T+ ++ ++ G + + +A D
Sbjct: 229 EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGR--QLQLGRAQSSDA 286
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENT--------------KAPEMKSR-RPKSSL 1210
G+Y C A N G AE + ++ V P E A E +R P +L
Sbjct: 287 GVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTL 346
Query: 1211 P------PVLGT-----ESDATVKKKPAP------------KTPPKAA---------MPP 1238
PV + E+D +V + +P +P A +PP
Sbjct: 347 SWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPP 406
Query: 1239 QIIQFPEDQKVR--AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
Q++ +V G+ +EL + +G+ T W++ + +E ++V + G+ L
Sbjct: 407 QLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQV--ASQGTTLH 464
Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
I +H G + N+ G+ A+V ++V
Sbjct: 465 IDHVELDHSGLFACQATNEAGTAGAEVEVSV 495
Score = 44.3 bits (103), Expect = 0.001
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
DV V G + L C+ P + W +G+ L + ++G S+ +E D
Sbjct: 2133 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL----EQGP--SLQLEAVGAGDS 2186
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
G Y CVA ++AG+A Q+TV + P E++ P S P
Sbjct: 2187 GTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTP 2227
Score = 43.5 bits (101), Expect = 0.002
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
++ V+E + C+ G P P + WFKD + S ++ Y G L + D
Sbjct: 229 EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTST--KVVYTRGGR-QLQLGRAQSSD 285
Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1858
YTCKA N++G A L V EG G
Sbjct: 286 AGVYTCKASNAVGAAEKATRLDVYVPPTIEGAG 318
Score = 43.5 bits (101), Expect = 0.002
Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
++V++G A C + G+P P++ WFKD + + I D L +
Sbjct: 1173 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD---GVLLQVLQANLSSA 1229
Query: 1827 AKYTCKAVNSLGEAT---CTAELIVETMEEGEGEGEEEE 1862
Y+C A N++GE T + L+ T+ G + +EE
Sbjct: 1230 GHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE 1268
Score = 43.1 bits (100), Expect = 0.003
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
+V V + + L+CQ + PP + W +G+ L+ + LS + +L + +++A D
Sbjct: 797 NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDA 854
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAP 1191
G Y C A N AG +E + V AP
Sbjct: 855 GHYTCEALNQAGHSEKHYNLNVWVAP 880
Score = 43.1 bits (100), Expect = 0.003
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Query: 1101 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKA 1160
++ +++V V + LQC +P TI W NG + + + ++G + VS +
Sbjct: 1567 EELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 1626
Query: 1161 LPEDRGLYKCVAKNDAGQAE 1180
D Y CVA+N AG AE
Sbjct: 1627 --ADAASYMCVAENQAGSAE 1644
Score = 42.7 bits (99), Expect = 0.003
Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 7/97 (7%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
D+ VV GS C+ G P P V W KD + + + + SL + V D
Sbjct: 2133 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL-------LSQSLEQGPSLQLEAVGAGD 2185
Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
Y+C AV+ GEA +L V E G+ E
Sbjct: 2186 SGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTE 2222
Score = 42.0 bits (97), Expect = 0.006
Identities = 77/363 (21%), Positives = 129/363 (35%), Gaps = 71/363 (19%)
Query: 987 GKKKLPAENGSSSAETLNA-----KAVESS---KPLSNAQPSGPLKPV-GNAKPAETLKP 1037
G+ +L +++G + E LNA K V+ S P P GP V L
Sbjct: 1714 GRARL-SDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSC 1772
Query: 1038 MGNAKPAETL------KPMGNAKPDENLKSASKEELKKDVKND---VNCKRGHAGTTDNE 1088
+A P T+ +P+ A+ + L+ + E+++ +D +CK +
Sbjct: 1773 ETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR 1832
Query: 1089 KRSESQGTAPAFKQ-KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI-IL 1146
+ + P F+ K + V G L+L C VS P T+ W + ++++ ++
Sbjct: 1833 TFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVV 1892
Query: 1147 SQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
S+ G L + + P G Y CVA+N +A V V AP R
Sbjct: 1893 SRGGRL---QLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP-------------RI 1936
Query: 1207 KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQP 1266
+SS + V G+ V L + G P
Sbjct: 1937 RSS--------------------------------GVAREHHVLEGQEVRLDCEADGQPP 1964
Query: 1267 ITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVN 1324
W+K + + + +G L + R G YT + N G +R VN
Sbjct: 1965 PDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVN 2024
Query: 1325 LTV 1327
+ V
Sbjct: 2025 VLV 2027
Score = 42.0 bits (97), Expect = 0.006
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRES--RHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
G + + DC + G P P++ W KD +R S RH + N SL I DD +Y
Sbjct: 2951 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRH------QLQNGSLTIRRTERDDAGRY 3004
Query: 1830 TCKAVNSLGEATCTAELIVET 1850
C A N +G A L++++
Sbjct: 3005 QCLAENEMGVAKKVVILVLQS 3025
Score = 41.6 bits (96), Expect = 0.007
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
C+ +P P + W KD SR+ Q+ G L I + +D +YTC N LG
Sbjct: 1281 CEALAFPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELG 1337
Query: 1839 EA 1840
EA
Sbjct: 1338 EA 1339
Score = 41.6 bits (96), Expect = 0.007
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
G A C+ + P+P V W+KD Q + ++ Q G L I + D Y+C
Sbjct: 1765 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQA---LRGGQRLEIQEAQVSDKGLYSC 1821
Query: 1832 KAVNSLGEATCTAELIVE 1849
K N GEA T L V+
Sbjct: 1822 KVSNVAGEAVRTFTLTVQ 1839
Score = 40.8 bits (94), Expect = 0.012
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 1766 DLEVVEG---SAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
DLE V S+ C + +P+PEV W+KD Q++ + G +L +
Sbjct: 1661 DLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV---FLLPGTHTLQLGRAR 1717
Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
D YTC+A+N+ G +L V
Sbjct: 1718 LSDSGMYTCEALNAAGRDQKLVQLSV 1743
Score = 40.4 bits (93), Expect = 0.016
Identities = 46/243 (18%), Positives = 84/243 (34%), Gaps = 53/243 (21%)
Query: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
+ E++G +++ + E L C ++ PP + W + L + + Q
Sbjct: 1466 REEEARGGVTEYRE------IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 1519
Query: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208
G + + + +A E+ G Y C A N+ G+ ++ V
Sbjct: 1520 GGRVLQIPLVRA--ENAGRYSCKASNEVGEDWLHYELLV--------------------- 1556
Query: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1268
PPV+ +++ V E+ V A +V L G T
Sbjct: 1557 LTPPVILGDTEELV----------------------EEVTVNASSTVSLQCPALGNPVPT 1594
Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
+W++ S ++V E+G L + A Y + EN+ GS + L V
Sbjct: 1595 ISWLQNGLPFSPSPRLQV--LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQ 1652
Query: 1329 DKP 1331
P
Sbjct: 1653 VPP 1655
Score = 39.3 bits (90), Expect = 0.036
Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 10/120 (8%)
Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1136
C ++ +D + R PA ++ + LL C+ S P ++W +G+
Sbjct: 2461 CLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQ 2520
Query: 1137 TLKTTKFIILSQEGSLCSVSIEKAL-----PEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
L Q+G+ + L P+D ++CV N+ G+A QVTV P
Sbjct: 2521 KLD-----FRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPP 2575
Score = 39.3 bits (90), Expect = 0.036
Identities = 65/278 (23%), Positives = 93/278 (33%), Gaps = 49/278 (17%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSVS 1156
P D V ++L C + P T+ W+ G L +S G+L
Sbjct: 2575 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL---E 2631
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP------------ASENTKAPEMKSR 1204
I +ALP G Y C A+N AG A +TV +P A E P S
Sbjct: 2632 IGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASG 2691
Query: 1205 RP-------KSSLPPVLGTESDA--------------------TVKKKPA----PKTPPK 1233
P K L G + + K A KT
Sbjct: 2692 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLV 2751
Query: 1234 AAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
+PP I D G L K G+ TW K + + +E K +G
Sbjct: 2752 VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEG-KFTIQPSG- 2809
Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
+L + + G YT EN +G + +V+LT++ P
Sbjct: 2810 ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLP 2847
Score = 38.9 bits (89), Expect = 0.047
Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 15/157 (9%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
++V V + L C+ + P I W +G + ++ I L + I A ED
Sbjct: 1267 EEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNAQKED 1324
Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPA-SENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
G Y CV N+ G+A + V V P+ S++ E+ + K+ + L E ++
Sbjct: 1325 AGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESW-- 1382
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
A PP I + + Q V +++ G+
Sbjct: 1383 ----------AVPPPTIRWYKDGQPVTPSSRLQVLGE 1409
Score = 38.1 bits (87), Expect = 0.081
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 12/103 (11%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIR-----ESRHFQIDYDE-------DGNCSLIIS 1819
G + +C G+P PE+VW KD Q + + + + + D SL
Sbjct: 33 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 92
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
+ D Y+C+A N G A L+V T G G +E
Sbjct: 93 RIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQE 135
Score = 38.1 bits (87), Expect = 0.081
Identities = 51/235 (21%), Positives = 84/235 (35%), Gaps = 55/235 (23%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F D + G +L L+C P I WT+N + + +S++ ++
Sbjct: 2847 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQR 2902
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT- 1216
ED G Y C A+N G+ + V V +AP + + + PV G+
Sbjct: 2903 AAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYL--------VEPVGGSI 2954
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
+ D V+ P P W+K
Sbjct: 2955 QLDCVVRGDPVP---------------------------------------DIHWIKDGL 2975
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
++ S H++ +NGS LTI ++ G Y L EN++G + V L + P
Sbjct: 2976 PLRGS-HLR-HQLQNGS-LTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSAP 3027
Score = 37.7 bits (86), Expect = 0.11
Identities = 52/250 (20%), Positives = 85/250 (34%), Gaps = 45/250 (18%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
GD A + TS++ RV+ + P P + + TA + G P
Sbjct: 2366 GDYSCTARNAAGSTSVAF---RVE---IHTVPTIRSGPPAVNVSVNQTALLPCQADGVPA 2419
Query: 62 PQVTWHRNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P V+W ++ P+ RF I SL I V +D G Y C A+N +G+ + +
Sbjct: 2420 PLVSWRKDRVPLDPRSPRF----EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD 2475
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
L V PA+ PS + +
Sbjct: 2476 LRV--------------------LEPPAIAPSPS--------------NLTLTAHTPALL 2501
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
C+ +G P+P V W K L + L + D + C+V N G
Sbjct: 2502 PCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVG 2561
Query: 241 KASMSAELSI 250
+A ++++
Sbjct: 2562 EAHRLYQVTV 2571
Score = 37.7 bits (86), Expect = 0.11
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P + + +L + + A C+ G P P VVW+KD Q + + R Q Y + +L+
Sbjct: 2482 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL-DFRLQQGAYRLLPSNALL 2540
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEA 1840
++ D A++ C N +GEA
Sbjct: 2541 LTAPGPQDSAQFECVVSNEVGEA 2563
Score = 37.4 bits (85), Expect = 0.14
Identities = 35/149 (23%), Positives = 56/149 (37%), Gaps = 8/149 (5%)
Query: 1694 WQKTG---NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVA 1750
W K G A R I L + L+ +K G T + E E+ ++ L +
Sbjct: 1293 WMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPS 1352
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
K P +++++ S +C+ P P + W+KD Q + S Q+ +
Sbjct: 1353 ISKDD--PLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGE- 1409
Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
L I D +Y C A N GE
Sbjct: 1410 --GRLLQIQPTQVSDSGRYLCVATNVAGE 1436
Score = 37.0 bits (84), Expect = 0.18
Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 8/105 (7%)
Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
W K G L S ++ G S + + G+ S + SE ++ + E
Sbjct: 2158 WMKDGEP------LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEP 2211
Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1798
PH++ T +L + G+ C +G P P + W KD Q++
Sbjct: 2212 PHIEDSGQPT--ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL 2254
Score = 36.6 bits (83), Expect = 0.23
Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 4/92 (4%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRE-SRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
G+ C G P P+V W KD Q + H Q+ EDG I G D+ +Y
Sbjct: 141 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQV--QEDGQVLRITGSHVG-DEGRYQ 197
Query: 1831 CKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
C A + G+ +L V G E E
Sbjct: 198 CVAFSPAGQQARDFQLRVHAPPTIWGSNETGE 229
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
+ VV+ A +C G P P V W +D Q + Q+ ++ SL +
Sbjct: 986 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQL---QNQGQSLHVERAQAAHT 1042
Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
+Y+C A N G A EL V
Sbjct: 1043 GRYSCVAENLAGRAERKFELSV 1064
Score = 36.6 bits (83), Expect = 0.23
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 3/74 (4%)
Query: 1778 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1837
+C +E P P++ W +D ++E H Q + E G L + + D Y+C A N+
Sbjct: 2320 ECSVEAEPAPKITWHRDGIVLQEDAHTQ--FPERGR-FLQLQALSTADSGDYSCTARNAA 2376
Query: 1838 GEATCTAELIVETM 1851
G + + + T+
Sbjct: 2377 GSTSVAFRVEIHTV 2390
Score = 36.6 bits (83), Expect = 0.23
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
V P F+ D + G C G P P + W +D+ + E ++DG +
Sbjct: 2845 VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS-----EQDGGST 2899
Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
L + V +D Y C A N +G + + V+ +GE
Sbjct: 2900 LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 2941
Score = 36.2 bits (82), Expect = 0.31
Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
V+ + R C G P P ++W KD + + + G L ++ D +
Sbjct: 707 VLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-LTLASARASDSGR 765
Query: 1829 YTCKAVNSLGE 1839
Y+C AV+++GE
Sbjct: 766 YSCVAVSAVGE 776
Score = 35.8 bits (81), Expect = 0.40
Identities = 32/153 (20%), Positives = 55/153 (35%), Gaps = 19/153 (12%)
Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
W K GN V +G G + G L + + S + AV E++
Sbjct: 729 WLKDGNPVSP----------AGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDR 778
Query: 1754 P------HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
H+ P ++ VV + +C+ P P + W+KD + + +
Sbjct: 779 QDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLS 838
Query: 1808 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
D+ L + D YTC+A+N G +
Sbjct: 839 ADK---ALLQVDRADVWDAGHYTCEALNQAGHS 868
Score = 35.8 bits (81), Expect = 0.40
Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 5/100 (5%)
Query: 1236 MPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
+PPQI + P V L TG P T TW + + + ++++N G
Sbjct: 972 VPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQ--G 1029
Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
L + A+ H G Y+ + EN G + + L+V+ P+
Sbjct: 1030 QSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPE 1069
Score = 35.4 bits (80), Expect = 0.52
Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 15/124 (12%)
Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
++ + G + L C P I W +G+ L T+ S+ + V D
Sbjct: 2222 ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL--TRLENNSRATRVLRV-------RDA 2272
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
GLY C+A++ AG E S +V V P + P L VL + +V+ +
Sbjct: 2273 GLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL--VL----ECSVEAE 2326
Query: 1226 PAPK 1229
PAPK
Sbjct: 2327 PAPK 2330
Score = 34.7 bits (78), Expect = 0.89
Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 3/70 (4%)
Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
V+E ++ +C G P P+V WFK Q + S + DG L I D
Sbjct: 615 VLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMGVTVSVDGRV-LRIEQAQLSDAGS 671
Query: 1829 YTCKAVNSLG 1838
Y C A N G
Sbjct: 672 YRCVASNVAG 681
Score = 34.3 bits (77), Expect = 1.2
Identities = 59/265 (22%), Positives = 90/265 (33%), Gaps = 65/265 (24%)
Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPE 1163
Q+V G + LQC S P + WT + + L + + ++G + ++
Sbjct: 134 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV--G 191
Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
D G Y+CVA + AGQ Q+ V AP P + G+ V
Sbjct: 192 DEGRYQCVAFSPAGQQARDFQLRV-HAP-------------------PTIWGSNETGEV- 230
Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
A M ++Q L + G TW K + S
Sbjct: 231 ----------AVMEDHLVQ--------------LLCEARGVPTPNITWFKDGALLPTS-- 264
Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP------------ 1331
KV + G +L + A+ G YT N +G+ + L V P
Sbjct: 265 TKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVV 324
Query: 1332 DPPAGTPCASDIRS---SSLTLSWY 1353
AG P A + + S TLSW+
Sbjct: 325 KAVAGRPVALECVARGHPSPTLSWH 349
Score = 33.5 bits (75), Expect = 2.0
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
L V EG R C+ G P P++ W KD Q + + + L + +
Sbjct: 890 LTVREGHPTRLSCECRGVPFPKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQE 948
Query: 1827 AKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1859
YTC+ N +G ++ +L V + G E
Sbjct: 949 GTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 981
Score = 33.1 bits (74), Expect = 2.6
Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
C+ G P P + WF+ ++ + + Y G L ++ D Y+C A N G
Sbjct: 1092 CEAMGIPPPAIRWFRGEEPVSPG---EDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 1148
Query: 1839 EATCTAELIVETMEEGEGEGEEEEE 1863
EA VE + E E+ EE
Sbjct: 1149 EA--RRNFSVEVLVPPSIENEDLEE 1171
Score = 32.0 bits (71), Expect = 5.8
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 3/84 (3%)
Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
H P + V A C+ +G P P V W KD + + R + + +G
Sbjct: 2388 HTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPL-DPRSPRFEILPEG-- 2444
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
SL I V D Y C A NS G
Sbjct: 2445 SLRIQPVLAQDAGHYLCLASNSAG 2468
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 12/101 (11%)
Query: 1751 EEKPHVKPYFS--KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY 1808
+ P VKP S + + + EV+ C+ G P P + W K+ ++ Q+
Sbjct: 2663 QASPVVKPLPSVVRAVAEEEVL------LPCEASGIPRPTITWQKEGLNVATGVSTQVL- 2715
Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
L I+ +D Y C A NS G A L+V+
Sbjct: 2716 ---PGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 2753
Score = 31.6 bits (70), Expect = 7.6
Identities = 27/130 (20%), Positives = 49/130 (37%), Gaps = 5/130 (3%)
Query: 1719 RKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFD 1778
R S G +S L + + +A L+ E + + ++ + + + G
Sbjct: 371 RLESPGEASSGLYS--CVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELP 428
Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
C+ G P P + W ++ + E Q+ +L I V D + C+A N G
Sbjct: 429 CQASGSPVPTIQWLQNGRPAEELAGVQV---ASQGTTLHIDHVELDHSGLFACQATNEAG 485
Query: 1839 EATCTAELIV 1848
A E+ V
Sbjct: 486 TAGAEVEVSV 495
Score = 31.6 bits (70), Expect = 7.6
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 3/71 (4%)
Query: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
V GS C + G P P V W KD + S + G L +S + Y
Sbjct: 1855 VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGV-VSRGGR--LQLSRLQPAQAGTY 1911
Query: 1830 TCKAVNSLGEA 1840
TC A N+ EA
Sbjct: 1912 TCVAENTQAEA 1922
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-D 1825
++ V G +C G+P P + W + + ES +++ D S++ + G+
Sbjct: 324 VKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDG----SVLRLESPGEAS 379
Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEE---GEGEGE 1859
Y+C A + GEA + V+ + EG G+
Sbjct: 380 SGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQ 416
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 158 bits (399), Expect = 5e-38
Identities = 99/324 (30%), Positives = 156/324 (48%), Gaps = 56/324 (17%)
Query: 1460 VSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHP 1519
+SDF+++E LG G V+R +K T+K +A K K +K+ +R EI ++ L HP
Sbjct: 42 LSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK--KTVDKKIVRTEIGVLLRLSHP 99
Query: 1520 KLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQ 1579
+++ + FE I +VLE+V+GGELF+RI+++ + +ER+ ++QI E V Y+H+
Sbjct: 100 NIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGY-YSERDAADAVKQILEAVAYLHEN 158
Query: 1580 GIVHLDLKPENIMCVNKT-GTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPI 1638
GIVH DLKPEN++ +K+ DFGL++ +E+ +K + GTP + APE++
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY 218
Query: 1639 GYATDMWSIGVICYIL-------------------------------------------- 1654
G DMWS+G+I YIL
Sbjct: 219 GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVR 278
Query: 1655 --------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGR 1706
RL Q LQHPW+ N ++ +++++ ARRK + AV A R
Sbjct: 279 KLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSR 338
Query: 1707 LSSMAMISGLSGRKSSTGSPTSPL 1730
L S + G SP+
Sbjct: 339 LGSASSSHGSIQESHKASRDPSPI 362
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 158 bits (399), Expect = 5e-38
Identities = 93/316 (29%), Positives = 158/316 (50%), Gaps = 55/316 (17%)
Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKE-NIRQEISIMNCL 1516
+ + D YD + LG+G F +V +K+T+K+ A K + + KE ++ EI++++ +
Sbjct: 14 EDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKI 73
Query: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576
HP +V D +E ++ +++++VSGGELF+RI+++ F TER+ + + Q+ + V+Y+
Sbjct: 74 KHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGF-YTERDASRLIFQVLDAVKYL 132
Query: 1577 HKQGIVHLDLKPENIMCVN-KTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635
H GIVH DLKPEN++ + ++I + DFGL++ + L GTP +VAPEV+
Sbjct: 133 HDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQ 192
Query: 1636 EPIGYATDMWSIGVICYIL----------------------------------------- 1654
+P A D WSIGVI YIL
Sbjct: 193 KPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDF 252
Query: 1655 ----------NRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1703
R C Q LQHPW+ DT + + +++KK A+ KW++ NA
Sbjct: 253 IRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAV 312
Query: 1704 IGRLSSMAMISGLSGR 1719
+ + + + + G+
Sbjct: 313 VRHMRKLQLGTSQEGQ 328
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 154 bits (390), Expect = 6e-37
Identities = 95/325 (29%), Positives = 156/325 (48%), Gaps = 55/325 (16%)
Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN-IRQEISIMNCL 1516
+ + ++ +E LG+G F +V EK T K++A K + K KE+ I EI+++ +
Sbjct: 17 EDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKI 76
Query: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576
H +V D +E ++ +V+++VSGGELF+RI+++ F TE++ +RQ+ + V Y+
Sbjct: 77 KHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGF-YTEKDASTLIRQVLDAVYYL 135
Query: 1577 HKQGIVHLDLKPENIMCVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635
H+ GIVH DLKPEN++ ++ ++I + DFGL++ + GTP +VAPEV+
Sbjct: 136 HRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ 195
Query: 1636 EPIGYATDMWSIGVICYIL----------------------------------------- 1654
+P A D WSIGVI YIL
Sbjct: 196 KPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDF 255
Query: 1655 ----------NRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1703
R C Q +HPW+ DT N + +++K A+ KW++ NA
Sbjct: 256 IRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAV 315
Query: 1704 IGRLSSMAMISGLSGRKSSTGSPTS 1728
+ + + + S L +S S S
Sbjct: 316 VRHMRKLHLGSSLDSSNASVSSSLS 340
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform 2
[Homo sapiens]
Length = 385
Score = 154 bits (390), Expect = 6e-37
Identities = 95/325 (29%), Positives = 156/325 (48%), Gaps = 55/325 (16%)
Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN-IRQEISIMNCL 1516
+ + ++ +E LG+G F +V EK T K++A K + K KE+ I EI+++ +
Sbjct: 17 EDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKI 76
Query: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576
H +V D +E ++ +V+++VSGGELF+RI+++ F TE++ +RQ+ + V Y+
Sbjct: 77 KHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGF-YTEKDASTLIRQVLDAVYYL 135
Query: 1577 HKQGIVHLDLKPENIMCVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635
H+ GIVH DLKPEN++ ++ ++I + DFGL++ + GTP +VAPEV+
Sbjct: 136 HRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ 195
Query: 1636 EPIGYATDMWSIGVICYIL----------------------------------------- 1654
+P A D WSIGVI YIL
Sbjct: 196 KPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDF 255
Query: 1655 ----------NRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1703
R C Q +HPW+ DT N + +++K A+ KW++ NA
Sbjct: 256 IRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAV 315
Query: 1704 IGRLSSMAMISGLSGRKSSTGSPTS 1728
+ + + + S L +S S S
Sbjct: 316 VRHMRKLHLGSSLDSSNASVSSSLS 340
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 152 bits (385), Expect = 2e-36
Identities = 114/400 (28%), Positives = 172/400 (43%), Gaps = 40/400 (10%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P+ S+PQ +V TV F C G PKPE+ W + + S D G+ L
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGT--LM 303
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVE-RLAVMEVAPSFSSVLKDCAVIEGQDFV 532
+ + D G Y C A N G++ T +V R P+F ++ V+ G+
Sbjct: 304 IQNTQETDQGIYQCMAKNVAGEVK---TQEVTLRYFGSPARPTFVIQPQNTEVLVGESVT 360
Query: 533 LQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
L+CS G P PRI+W + P+ + +G L+IQ+ + D G Y C A N +
Sbjct: 361 LECSATGHPPPRISWTRGDRTPLPVDPRVNITPSG--GLYIQNVVQGDSGEYACSATNNI 418
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
V +A++ V P F D V++G V + GN
Sbjct: 419 DSVHATAFIIVQ-------------------ALPQFTVTPQDRVVIEGQTVDFQCEAKGN 459
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
PPP + W G+++ GT L I V D G Y C+A N G + A
Sbjct: 460 PPPVIAWTKGGSQLSVDRRHLVLSSGT---LRISGVALHDQGQYECQAVNIIGSQKVVAH 516
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
LTVQ P F S P T +G +V + C+ G+P P + W +DG + ++G F
Sbjct: 517 LTVQ---PRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQV-TESGKFH 572
Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
+ + + F L + V P AG+YE + +N +G S + L
Sbjct: 573 I--SPEGF-LTINDVGPADAGRYECVARNTIGSASVSMVL 609
Score = 123 bits (308), Expect = 2e-27
Identities = 85/325 (26%), Positives = 130/325 (40%), Gaps = 29/325 (8%)
Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
+++V + + + + A P F +PQ+ EV ++V C +G P P ++W
Sbjct: 319 AKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRG 378
Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510
+ + + G + +++ DSG Y+C+A+N + + + V+ L
Sbjct: 379 DRTPLPVDPRVNITPSGGLYIQNVVQG---DSGEYACSATNNIDSVHATAFIIVQAL--- 432
Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI 570
P F+ +D VIEGQ QC +G P P I W G + R L I
Sbjct: 433 ---PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRI 489
Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
D G Y C A N +G A +TV + P+F S
Sbjct: 490 SGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR-----------------VTPVFASIPS 532
Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
D V G+ V + G P P + W +G ++ ES FH G L I +V P D
Sbjct: 533 DTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEG---FLTINDVGPADA 589
Query: 691 GTYTCEAWNSAGEVRTQAVLTVQEP 715
G Y C A N+ G VL+V P
Sbjct: 590 GRYECVARNTIGSASVSMVLSVNVP 614
Score = 92.0 bits (227), Expect = 5e-18
Identities = 82/279 (29%), Positives = 117/279 (41%), Gaps = 27/279 (9%)
Query: 344 SITLQ-AARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK----- 397
S+TL+ +A P PR + G+ P PR P+ GL Q+VV
Sbjct: 358 SVTLECSATGHPPPR-----ISWTRGDRTPLPVDPRVNITPSG--GLYIQNVVQGDSGEY 410
Query: 398 AANRRIPMEGQRDSAF------PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEG 451
A + ++ +AF P+F PQ + V E QTV F+CE G P P +AW G
Sbjct: 411 ACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGG 470
Query: 452 TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME 511
+ + + + S L + D G Y C A N G L V+
Sbjct: 471 SQLSVDRRHLVL----SSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQP----R 522
Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ 571
V P F+S+ D V G + L CS +G P P ITW +G + + + L I
Sbjct: 523 VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTIN 582
Query: 572 DALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
D P D G Y C+A N +G S S ++V+ SR +
Sbjct: 583 DVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGD 621
Score = 82.4 bits (202), Expect = 4e-15
Identities = 60/218 (27%), Positives = 93/218 (42%), Gaps = 39/218 (17%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F + P++ + EG T F+ +G P P + W + G ++ R L + + +L
Sbjct: 433 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHL----VLSSGTLR 488
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I V D+G+Y C+A N G+++V LTV QP V+
Sbjct: 489 ISGVALHDQGQYECQAVNIIGSQKVVAHLTV---------QPRVT--------------- 524
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212
P FA+ V+ G + C G P+P +TW K V + S + +S +
Sbjct: 525 --------PVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPE 576
Query: 213 NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
L I+ V D G Y C+ N G AS+S LS+
Sbjct: 577 G---FLTINDVGPADAGRYECVARNTIGSASVSMVLSV 611
Score = 73.2 bits (178), Expect = 2e-12
Identities = 62/227 (27%), Positives = 90/227 (39%), Gaps = 42/227 (18%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI---TSGGRFLLDCGIRG 87
E P P++ + G T F R G P+P++ W RN + T LLD G
Sbjct: 244 ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG--- 300
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
+L+I E D+G Y C A N +G + T E+T+ F +P
Sbjct: 301 --TLMIQNTQETDQGIYQCMAKNVAGEVK-TQEVTLR------------------YFGSP 339
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN-VPLQPSAR 206
A P F + V G+ C TG P P+++W +G+ PL R
Sbjct: 340 A-----------RPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPR 388
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
V+++ G L I V Q D G Y C N +A + +Q L
Sbjct: 389 VNITPSGG---LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL 432
Score = 56.2 bits (134), Expect = 3e-07
Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 4/108 (3%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F P + ++ GA + +G PEP +TW+++G +T G+F I L
Sbjct: 525 PVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKF----HISPEGFLT 580
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
I+ V D G+Y C A N G+ V++ L+V + G P V+ ++
Sbjct: 581 INDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVATSI 628
Score = 53.5 bits (127), Expect = 2e-06
Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 4/96 (4%)
Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
+P V P F+ D V G+ + C +G P+P + W KD + ES F I +
Sbjct: 520 QPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEG-- 577
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
L I+DV D +Y C A N++G A+ + L V
Sbjct: 578 --FLTINDVGPADAGRYECVARNTIGSASVSMVLSV 611
Score = 52.4 bits (124), Expect = 4e-06
Identities = 67/291 (23%), Positives = 104/291 (35%), Gaps = 66/291 (22%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK--TLKTTKFIILSQEGSLCSV 1155
P + QD V G + C+ +P IIW N ++KT + L +G+L
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTL--- 302
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD--DAPA-------SENTKAPEMKSRRP 1206
I+ D+G+Y+C+AKN AG+ + +VT+ +PA +NT+ +S
Sbjct: 303 MIQNTQETDQGIYQCMAKNVAGEVKTQ-EVTLRYFGSPARPTFVIQPQNTEVLVGESVTL 361
Query: 1207 KSSL-----PPVLGTESDATVKKKPAPKTPPKAAMP------------------------ 1237
+ S P + T D T P P P P
Sbjct: 362 ECSATGHPPPRISWTRGDRT----PLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNN 417
Query: 1238 ---------------PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
PQ P+D+ V G++V+ + G P W K Q+
Sbjct: 418 IDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDR 477
Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
V +S L I G Y N +GS++ +LTV + P
Sbjct: 478 RHLVLSS---GTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTP 525
Score = 52.4 bits (124), Expect = 4e-06
Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 6/93 (6%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHFQIDYDEDGNCSL 1816
P F+ T +D V+EG F C+ +G P P + W K + + RH + + +L
Sbjct: 433 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVL-----SSGTL 487
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
IS V D +Y C+AVN +G A L V+
Sbjct: 488 RISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ 520
Score = 50.1 bits (118), Expect = 2e-05
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
EE +P + +D +V G+ F C+ EG P PE++W +++ + +++ +
Sbjct: 239 EELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLD 298
Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
DG +L+I + D Y C A N GE
Sbjct: 299 DG--TLMIQNTQETDQGIYQCMAKNVAGE 325
Score = 47.8 bits (112), Expect = 1e-04
Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 3/98 (3%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P F D V G + L C +P I W +G + + +S EG L +I
Sbjct: 525 PVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFL---TI 581
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195
P D G Y+CVA+N G A S ++V+ S N
Sbjct: 582 NDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRN 619
Score = 46.6 bits (109), Expect = 2e-04
Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 4/114 (3%)
Query: 705 RTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKD 764
R+ A +T +E + +P S+P+ + G +V +C G+P P + WLR+ L
Sbjct: 231 RSVATITPEELNC-ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMK 289
Query: 765 TGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ-VSLMLQNSSAR 817
T L D TL+++ Q G Y+ + KN GE Q V+L S AR
Sbjct: 290 TD--SRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPAR 341
Score = 44.7 bits (104), Expect = 9e-04
Identities = 65/296 (21%), Positives = 100/296 (33%), Gaps = 56/296 (18%)
Query: 1080 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT-L 1138
G T + R P F + Q+ V G+ + L+C + PP I WT +T L
Sbjct: 324 GEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPL 383
Query: 1139 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1198
+ ++ G L I+ + D G Y C A N+ + + V P + T
Sbjct: 384 PVDPRVNITPSGGL---YIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALP--QFTVT 438
Query: 1199 PEMK----------SRRPKSSLPPVL-----GTE----------SDATVK---------- 1223
P+ + K + PPV+ G++ S T++
Sbjct: 439 PQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQG 498
Query: 1224 ------------KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
+K + + P P D V G +V+L G TW
Sbjct: 499 QYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITW 558
Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
K Q+ ES K S G LTI G Y + N +GS + L+V
Sbjct: 559 NKDGVQVTESG--KFHISPEGF-LTINDVGPADAGRYECVARNTIGSASVSMVLSV 611
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 11/101 (10%)
Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS- 1815
+P F ++ EV+ G + +C G+P P + W + D++ + D N +
Sbjct: 341 RPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRT-------PLPVDPRVNITP 393
Query: 1816 ---LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
L I +V D +Y C A N++ TA +IV+ + +
Sbjct: 394 SGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQ 434
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 151 bits (381), Expect = 7e-36
Identities = 88/298 (29%), Positives = 148/298 (49%), Gaps = 53/298 (17%)
Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLH 1517
+K+ FY+++E +G G FG V R+ K + + A KF S + R+ I+ L
Sbjct: 6462 RKLHSFYEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYRER-DILAALS 6520
Query: 1518 HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIH 1577
HP + +D FE + ++++LE+ S EL +R+ + +TE E Y++Q+ EG+ Y+H
Sbjct: 6521 HPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGV-VTEAEVKVYIQQLVEGLHYLH 6579
Query: 1578 KQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEP 1637
G++HLD+KP NI+ V+ IK+ DFG A+ + A +G+PEFV+PE+I P
Sbjct: 6580 SHGVLHLDIKPSNILMVHPAREDIKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNP 6639
Query: 1638 IGYATDMWSIGVICY-----------------ILNRLD---------------------- 1658
+ A+D+W++GVI Y +LN L+
Sbjct: 6640 VSEASDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIK 6699
Query: 1659 ------------CTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAI 1704
QCL HPW +K EA ++ ++K +AR +WQ++ + ++I
Sbjct: 6700 ATLQRAPQARPSAAQCLSHPWFLKSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSI 6757
Score = 143 bits (361), Expect = 1e-33
Identities = 156/641 (24%), Positives = 245/641 (38%), Gaps = 96/641 (14%)
Query: 129 KQLGQPVVSKTLGDRFSA-PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGR 187
K LG P + K +A + R + + P F+ G + G R C + +
Sbjct: 4865 KDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASK 4924
Query: 188 PQPQVTWLKGNVPLQPSARVSVSEK-NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
+ WLK V L + + +G L I G+++ D G YTC V N G+ + SA
Sbjct: 4925 ADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSA 4984
Query: 247 ELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP 306
+ + G +S S + D + + + + S + + S G +
Sbjct: 4985 CVVVSGSESEAES---SSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAE 5041
Query: 307 P-----WAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
P W + + + E+ ++ + + + T I ++ V+ PR +
Sbjct: 5042 PEEPADWQTYREDEHFICIRFEALTEARQAVTRFQEMFATLG-IGVEIKLVEQGPRRVEM 5100
Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
+ ++ PAP P P P L + D A P F ++ Q
Sbjct: 5101 CI------SKETPAPVVP---PEPLPSLLTSD------------------AAPVFLTELQ 5133
Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481
+QEV++ V F C V+G P P V WF +G + + + + G H L + D
Sbjct: 5134 NQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPAD 5193
Query: 482 SGTYSCTASNAQGQLSCSWTLQVERLAV--------MEVAPSFSSV-------------- 519
G Y C A N+ G S L+V+ + E + FS+
Sbjct: 5194 MGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSREQEGTEST 5253
Query: 520 ------------LKDCAVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQ---YARSTCEA 563
L+D V G Q V+G P PR+ W +GQP+ + R T +
Sbjct: 5254 TDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKK 5313
Query: 564 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH------EKKSSRKSEYLLPVAP 617
+ L I ED G Y NA+G SA + V EK +S E L+P
Sbjct: 5314 ILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVP--- 5370
Query: 618 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI------QESEDFHF 671
P L+ + KV GS +T +V+V G P P V WL E ++ +
Sbjct: 5371 -----PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV 5425
Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
QHSL + +V + GTYTC A N+AG+ A L V
Sbjct: 5426 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466
Score = 119 bits (298), Expect = 3e-26
Identities = 106/376 (28%), Positives = 142/376 (37%), Gaps = 61/376 (16%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGS-IEVYEDAGSHYL 472
P F +P S V+E FRC V G P+P V+W +G + +G + V E + L
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASAL 169
Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV----------------------- 509
+ AR RD GTY A N G S + L V+ A
Sbjct: 170 RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229
Query: 510 --MEVAPSF--SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV 565
E AP+ S+ + C V EG+ L C V G P P W +GQ + R
Sbjct: 230 MRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYED 289
Query: 566 AE----LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
A+ L I D G YTC A N +GQ S V V E P
Sbjct: 290 AQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE-----------------PA 332
Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
P F + L DL+V + T +V P E W + S + E+ GT+ L
Sbjct: 333 VP-FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIEEEGTERRLT 390
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
++ V +D Y CE + RT A L VQ PR +G + +
Sbjct: 391 VRNVSADDDAVYICETPEGS---RTVAELAVQ------GNLLRKLPRKTAVRVGDTAMF- 440
Query: 742 CAIAGDPFPTVHWLRD 757
C P VHWLR+
Sbjct: 441 CVELAVPVGPVHWLRN 456
Score = 119 bits (297), Expect = 4e-26
Identities = 93/337 (27%), Positives = 143/337 (42%), Gaps = 32/337 (9%)
Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
M+ + S P+F ++P++ V + C++ G P P+V+W + PV +
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPV-AAGARFRLA 59
Query: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE-RLAVMEVAPSFSSVLKDC 523
+D + L +L DSG Y C A NA G+ + LQV+ A E AP F
Sbjct: 60 QDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSI 119
Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLN----GQPIQYARSTCEAGVAE-LHIQDALPEDH 578
V EG + +C V G+P P ++W + G+P E G A L I+ A P D
Sbjct: 120 RVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDG 179
Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKSS------------------RKSEYLLPVAPSKP 620
GTY AEN LG S +A + V + R+ AP+ P
Sbjct: 180 GTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASP 239
Query: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680
+ G V +G ++ V+G P PE +W +G + E H Q +
Sbjct: 240 PS----TGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR-HVVYEDAQENF 294
Query: 681 CIQEVF--PEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
++ +F D G YTC A N G+ + ++ V+EP
Sbjct: 295 VLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREP 331
Score = 117 bits (294), Expect = 8e-26
Identities = 123/460 (26%), Positives = 197/460 (42%), Gaps = 54/460 (11%)
Query: 1215 GTESDATVKKKPAPKTPPKAAMP-----PQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1269
G E + +KKP + + + P ++ D+ V G+SV L +V+
Sbjct: 7435 GLEKEGPPRKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQA 7494
Query: 1270 TWMKFRKQIQESEHMKVENS-ENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT-V 1327
TW K ++ S + + + +N LTIL E G YT V N LG+ V T V
Sbjct: 7495 TWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGT----VTTTGV 7550
Query: 1328 VDKPDPPAGTPCAS--DIRSSSLTLSWYG-SSYDGGSAVQSYSIEIWDSANKTWKELAT- 1383
+ K + P+ +PC ++ + + L W SY + + S+E +W LA+
Sbjct: 7551 LRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVTYIVQCSLE-----GGSWTTLASD 7605
Query: 1384 ----CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
C TS L Y FR ++ G S SE +G P E E S
Sbjct: 7606 IFDCCYLTS----KLSRGGTYTFRTACVSKAGMGPYSSPSEQVLLGG-PSHLASEEE-SQ 7659
Query: 1440 DDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYS 1499
+P +T T+ + G+F V + EK + + A K Y
Sbjct: 7660 GRSAQPLPSTKTFAFQTQ------------IQRGRFSVVRQCWEKASGRALAAKIIP-YH 7706
Query: 1500 AKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTE 1559
K+K + +E + L HP L Q A+ ++V++LE+ SG EL + E +E
Sbjct: 7707 PKDKTAVLREYEALKGLRHPHLAQLHAAYLSPRHLVLILELCSGPELLP-CLAERASYSE 7765
Query: 1560 RECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLK 1619
E Y+ Q+ +Y+H Q I+HLDL+ EN++ +K++D G A+ L K
Sbjct: 7766 SEVKDYLWQMLSATQYLHNQHILHLDLRSENMIITEY--NLLKVVDLGNAQSLSQE---K 7820
Query: 1620 VLFGTP-----EFVAPEVINYEPIGYATDMWSIGVICYIL 1654
VL E +APE++ + TD+W+IGV +I+
Sbjct: 7821 VLPSDKFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIM 7860
Score = 117 bits (292), Expect = 1e-25
Identities = 287/1336 (21%), Positives = 478/1336 (35%), Gaps = 229/1336 (17%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
P KF L EG C+++ V W KG L+ R + ++ L+
Sbjct: 3449 PAKFTEGLRNEEAVEGATAMLWCELS--KVAPVEWRKGPENLRDGDRYILRQEGTRCELQ 3506
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I G+ D G Y C+ G+ SA L+I+ L + F+ + K N + R+ T V+
Sbjct: 3507 ICGLAMADAGEYLCVC----GQERTSATLTIRALPAR---FIEDVK--NQEAREGATAVL 3557
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVL- 338
E L+S A + + S R G + + + + D T + V
Sbjct: 3558 QCE--LNSA-APVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMAD---TGEYSCVCG 3611
Query: 339 -QKTSSSITLQAARVQ------PEPRAPG--------LGVLSP----SGEERKRPAPPRP 379
++TS+ +T++A ++ E G L ++P G E R
Sbjct: 3612 QERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAPVEWWKGHETLRDGDRHS 3671
Query: 380 ATFPTRQPGLGSQDVVSKAANRRIPMEG-QRDSAFPKFESKP-------QSQEVKENQTV 431
+ L + +V++ A + M G +R SA + P +++E E T
Sbjct: 3672 LRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTA 3731
Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL------CLLKAR---TRDS 482
CE+S + PV ++G E D H L C L+ R D+
Sbjct: 3732 TLWCELS-----------KAAPVEWRKGH-ETLRDGDRHSLRQDGSRCELQIRGLAVVDA 3779
Query: 483 GTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
G YSC GQ S TL V L F +K+ EG VLQC + +
Sbjct: 3780 GEYSCVC----GQERTSATLTVRALPAR-----FIEDVKNQEAREGATAVLQCEL--SKA 3828
Query: 543 PRITWLLNGQPIQYAR--STCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
+ W + ++ S + G EL I D G Y+C+ GQ SA +T
Sbjct: 3829 APVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLT 3884
Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
V AP P+F + L L+ +GS T+ ++S P V+W
Sbjct: 3885 VR--------------APQ----PVFREPLQSLQAEEGSTATLQCELS-EPTATVVWSKG 3925
Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
G ++Q + +G L +Q++ EDTG YTC + G T A LTV
Sbjct: 3926 GLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC----TCGSQATSATLTV----TAA 3977
Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
F+ + + G + + C ++ +V W R G ++++Q+ L
Sbjct: 3978 PVRFLRELQHQEVDEGGTAHLCCELS-RAGASVEW-RKGSLQLFPCAKYQMVQDGAAAEL 4035
Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839
+++ V+ AG Y + S V + R +E LC A+
Sbjct: 4036 LVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLCCQLSDAE 4095
Query: 840 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETR-----------QHTEEAIR 888
G ++ L+ G E R +L ++E + Q T ++R
Sbjct: 4096 SGAVVQW--LKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAASLR 4153
Query: 889 QQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSP 948
E E R L+ +V+ E ++F + R T + +
Sbjct: 4154 VTEPEVTIVRGLVDAEVTAD------------EDVEFSCEVSR--AGATGVQWCLQGLPL 4199
Query: 949 QQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAV 1008
Q + V + G T + V P T F LG + SS+ T+ A V
Sbjct: 4200 QSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFH--LG-------NHASSAQLTVRAPEV 4250
Query: 1009 ESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDEN-LKSASKEE- 1066
+PL + Q + + A + A E +G N + + E+
Sbjct: 4251 TILEPLQDVQ-------LSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQG 4303
Query: 1067 ------LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
L K D H GT +E + + + L++V EG + L +CQ
Sbjct: 4304 TLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNTVVR-GLENVEALEGGEALFECQ 4362
Query: 1121 VSSDPPATIIWTLNGKTLKTTK--FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1178
+S A W L+ + + T++ ++ + G + ++ P+D
Sbjct: 4363 LSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQD-------------- 4408
Query: 1179 AECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPP 1238
SC+VT L + T + TV+
Sbjct: 4409 ---SCRVTF----------------------LAGDMVTSAFLTVR-----------GWRL 4432
Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPI-TCTWMKFRKQIQ-ESEHMKVENSENGSKLT 1296
+I++ ++ VRAG ++ P+ +W +Q + V + L
Sbjct: 4433 EILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALL 4492
Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1356
+ +A+ H G T + + A LTV+ PDPP + S ++TLSW
Sbjct: 4493 LRSAQPHHAGEVTFACRDAV----ASARLTVLGLPDPPEDAEVVAR-SSHTVTLSWAAPM 4547
Query: 1357 YDGGSAVQSYSIEIWDSANKTWK---ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
DGG + Y +E+ + A W+ EL V L P Y+FRV A+ G
Sbjct: 4548 SDGGGGLCGYRVEVKEGATGQWRLCHELVP--GPECVVDGLAPGETYRFRVAAVGPVGAG 4605
Query: 1414 EPSQESELTTVGEKPE 1429
EP + + E P+
Sbjct: 4606 EPVHLPQTVRLAEPPK 4621
Score = 117 bits (292), Expect = 1e-25
Identities = 117/500 (23%), Positives = 199/500 (39%), Gaps = 81/500 (16%)
Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85
++P+ P F + + G T K RV G P+P ++W+++G+ + +L
Sbjct: 6007 ALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDP 6066
Query: 86 RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G+ +L++ ++ D G+Y C A + +G TLG
Sbjct: 6067 DGSCALILDSLTGVDSGQYMCFAASAAGN----------------------CSTLG---- 6100
Query: 146 APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
I + PP+F K+ EG+ +F+C I G P PQ+ W K L
Sbjct: 6101 --------KILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGN 6152
Query: 206 RV-SVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG--LDSANRSFV 261
+ ++SE ++G+ VL I +++D+G+Y C +VN G A SAEL IQ L + +
Sbjct: 6153 KFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 6212
Query: 262 RETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321
+ A D E + E + K P+ G P
Sbjct: 6213 EQLVAAVEDTTLERAD----------QEVTSVLKRLLGPKAPG------------PSTGD 6250
Query: 322 LESCKDSPRTAPQTPVLQKTSSSITLQAARVQP--EPRAPGLGVLSPSGEERKRPAPPRP 379
L PR A P LQ+T S + P PR P + +E + A +
Sbjct: 6251 LTGPGPCPRGA---PALQETGSQPPVTGTSEAPAVPPRVPQPLLHEGPEQEPEAIARAQE 6307
Query: 380 ATFPTRQ-----PGLGSQDVVSKAANRRIPMEGQRDSAFPKFE---SKPQSQEV------ 425
T P R PG G+ +++ + + QR + + ++P S +V
Sbjct: 6308 WTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIEDVQ 6367
Query: 426 -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
+ T +F + G P+P V W+ + + + ++ ++ L L ++D+G
Sbjct: 6368 AQTGGTAQFEAIIEGDPQPSVTWYKDSVQL-VDSTRLSQQQEGTTYSLVLRHVASKDAGV 6426
Query: 485 YSCTASNAQGQLSCSWTLQV 504
Y+C A N GQ+ C L V
Sbjct: 6427 YTCLAQNTGGQVLCKAELLV 6446
Score = 117 bits (292), Expect = 1e-25
Identities = 118/442 (26%), Positives = 176/442 (39%), Gaps = 53/442 (11%)
Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
P FE + + +TVK C V+G PKP ++W+ +G V+ I + + GS L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
L DSG Y C A++A G +CS ++ +++V P F + ++ +EG+D
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAG--NCSTLGKI----LVQVPPRFVNKVRASPFVEGEDAQF 6127
Query: 534 QCSVRGTPVPRITWLLNGQPIQYAR-----STCEAGVAELHIQDALPEDHGTYTCLAENA 588
C++ G P P+I W +G + S +G+ L I+ A ED G Y C N
Sbjct: 6128 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187
Query: 589 LGQVSCSAWVTVH----------------------------EKKSSRKSEYLLPVAPSKP 620
LG SA + + ++ +S L P AP
Sbjct: 6188 LGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTSVLKRLLGPKAPGPS 6247
Query: 621 TAPIFLQGL----SDLKVMDGSQ--VTMTVQVSGNPP--PEVIWLHNGNEIQESEDFHFE 672
T + G + GSQ VT T + PP P+ + LH G E QE E
Sbjct: 6248 TGDLTGPGPCPRGAPALQETGSQPPVTGTSEAPAVPPRVPQPL-LHEGPE-QEPEAIARA 6305
Query: 673 QRGTQHSLCIQEVFP-EDTGTYTCEAWNSAGEVRTQAVLTVQ--EPHDGTQPWFISKPRS 729
Q T +P TG + + TQ T Q + H P
Sbjct: 6306 QEWTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIED 6365
Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
V A G + I GDP P+V W +D L D+ Q ++LVL+ V A
Sbjct: 6366 VQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLV-DSTRLSQQQEGTTYSLVLRHVASKDA 6424
Query: 790 GQYEILLKNRVGECSCQVSLML 811
G Y L +N G+ C+ L++
Sbjct: 6425 GVYTCLAQNTGGQVLCKAELLV 6446
Score = 112 bits (279), Expect = 4e-24
Identities = 106/409 (25%), Positives = 170/409 (41%), Gaps = 51/409 (12%)
Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
+V+E + FRC +S V WFL+ TP+ E + + G H L L + +DSG
Sbjct: 3015 DVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG 3074
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
T A + + + L V E FS L D + EG+D L C +P
Sbjct: 3075 TIYFEAGDQRASAA---------LRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP 3125
Query: 544 RITWLLNGQPIQ---YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
+ W +G+ ++ + + E A+L I A +D G Y C A G S+ V V
Sbjct: 3126 -VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACSSSIVRV 3180
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
H + PV F + L DL+V++G T+ +S P V W +
Sbjct: 3181 HAR----------PVR--------FQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGN 3221
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
N ++ + + Q G L ++ + P+D+G Y+C S G+ T A LTV
Sbjct: 3222 NVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLTV----TALP 3273
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
FI K R+ A+ G + + C ++ V W R G +D + + Q+ + L
Sbjct: 3274 AQFIGKLRNKEATEGATATLRCELS--KAAPVEW-RKGSETLRDGDRYCLRQDGAMCELQ 3330
Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCE 829
++ + A +Y + GE SL ++ A + R R S E
Sbjct: 3331 IRGLAMVDAAEYSCV----CGEERTSASLTIRPMPAHFIGRLRHQESIE 3375
Score = 112 bits (279), Expect = 4e-24
Identities = 90/346 (26%), Positives = 141/346 (40%), Gaps = 43/346 (12%)
Query: 507 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCE 562
L + AP F + L++ V +G C V G P+P + W +G+ ++ Y + +
Sbjct: 5119 LLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178
Query: 563 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH-------------EKKSSRKS 609
G +L I +P D G Y CLAEN++G S A + V E S +
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238
Query: 610 EYLLPVAPSKPTA--------PIFLQGLSDLKVMDGSQVT-MTVQVSGNPPPEVIWLHNG 660
+ L + T P ++ L DL+V G+++ ++V G P P + W +G
Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDG 5298
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
+ S + H+L I V ED+G Y N+ G + A L V+ P + +
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEE 5358
Query: 721 ------------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA-----LCK 763
P + + G S+ S + G P PTVHWLR+ +
Sbjct: 5359 KPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGP 5418
Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
DT + V + +LVL V H G Y + N G+ C SL
Sbjct: 5419 DTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASL 5464
Score = 104 bits (259), Expect = 9e-22
Identities = 133/567 (23%), Positives = 214/567 (37%), Gaps = 80/567 (14%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P+F T+ VV G+ SC+I G P PQV+W K P+ AR +++ + L I
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
+ D G Y C N G+A + L + + ++ + +
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVDA---------------EAACAEQAPHFLL 114
Query: 281 KESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK 340
+ + + E + + C + GGSP A + R + D PR +
Sbjct: 115 RPTSIRVREGSEATFRC---RVGGSPRPAVSWSKDGRRLGE----PDGPRVRVEE---LG 164
Query: 341 TSSSITLQAARVQPEPRAPG---LGVLSPSGEERKRPA--PPRPATFPTRQPGLGSQDVV 395
+S++ ++AAR PR G + +P G A A +PG + ++
Sbjct: 165 EASALRIRAAR----PRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALL 220
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
+ RR M + A P + ++ V E + + C V+G PKPE W +G V
Sbjct: 221 AHLQRRREAMRAEGAPASPP-STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVT 279
Query: 456 RQEGSIEVYEDAGSHY-LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAP 514
+ VYEDA ++ L +L + D G Y+CTASN GQ T + V E A
Sbjct: 280 EGRRHV-VYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ-----TYSSVLVVVREPAV 333
Query: 515 SFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE------L 568
F L+D V E + C V P W + ++ + G+ E L
Sbjct: 334 PFKKRLQDLEVREKESATFLCEV-PQPSTEAAWFKEETRLW---ASAKYGIEEEGTERRL 389
Query: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 628
+++ +D Y C V+ A +K RK+
Sbjct: 390 TVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTA------------------ 431
Query: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
++V D + + + V P V WL N E+ GT+H+L I + E
Sbjct: 432 ---VRVGDTAMFCVELAVPVGP---VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLE 485
Query: 689 DTGTYTCEAWNSAGEVRTQAVLTVQEP 715
D G + AG+ +T V P
Sbjct: 486 DVG----QVAFMAGDCQTSTQFCVSAP 508
Score = 103 bits (256), Expect = 2e-21
Identities = 84/337 (24%), Positives = 132/337 (39%), Gaps = 53/337 (15%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELH 569
AP F + K V G+D L C + G P P+++W + QP+ R + + L
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLT 68
Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 629
I D D G Y C A NA+G+ + + V + A AP FL
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAE------------AACAEQAPHFLLRP 116
Query: 630 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHSLCIQEVFP 687
+ ++V +GS+ T +V G+P P V W +G + E + E+ G +L I+ P
Sbjct: 117 TSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARP 176
Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL------------- 734
D GTY A N G A L V T S+P + TA+L
Sbjct: 177 RDGGTYEVRAENPLGAASAAAALVVDSDAADT----ASRPGTSTAALLAHLQRRREAMRA 232
Query: 735 -------------------GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
G+ +SC + G+P P W +DG+ + + H ++
Sbjct: 233 EGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQE 292
Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
F L + + G Y N VG+ V ++++
Sbjct: 293 NFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR 329
Score = 100 bits (249), Expect = 1e-20
Identities = 189/808 (23%), Positives = 308/808 (38%), Gaps = 116/808 (14%)
Query: 29 LTEAP-AFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
+TE P +F P +++ E E + P V W ++G + +G + +G
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKTMAI--AAQG 2217
Query: 88 TF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD-RFS 145
SL I+ D+G Y C+A + Q + + V+G + + V+++ G+ +F
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTYTLIYRRVLAEDAGEIQFV 2273
Query: 146 APAVETRPSIW-GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
A E+R + E P L + E G C+++ R QV W KG+ LQP
Sbjct: 2274 AENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVS-RASAQVRWFKGSQELQPG 2332
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
+ + + L I V+ +D YTC +G SA+ ++ +S
Sbjct: 2333 PKYELVSDGLYRKLIISDVHAEDEDTYTC----DAGDVKTSAQFFVE-----EQSITIVR 2383
Query: 265 KATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLES 324
+ V + E+ + S+ + Q GG+ + R +
Sbjct: 2384 GLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNV--GLEQEGTVHRLMLRRT 2441
Query: 325 CKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSP-SGEERK--------RPA 375
C S T P + K+ SS L + + P L P +G E + RPA
Sbjct: 2442 C--STMTGPVHFTVGKSRSSARLVVSDIPVVLTRP----LEPKTGRELQSVVLSCDFRPA 2495
Query: 376 PPRPATFPTRQPGLGSQ----DVVSKAANRRI----PMEG-----QRDSAFPKFESKPQS 422
P + P S+ + + A RI P + Q SA E ++
Sbjct: 2496 PKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEA 2555
Query: 423 QEV-----------KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
+EV E F CE+S EV W L G P+ + E+ H
Sbjct: 2556 REVTVTGPLQDAEATEEGWASFSCELSH-EDEEVEWSLNGMPL-YNDSFHEISHKGRRHT 2613
Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
L L + D+G ++ ++S S L+V V+ F L D + E
Sbjct: 2614 LVLKSIQRADAGIVRASSL----KVSTSARLEVRVKPVV-----FLKALDDLSAEERGTL 2664
Query: 532 VLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
LQC V P + W +G P AG L + D PED G YTC
Sbjct: 2665 ALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC----H 2719
Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
+G A V VH+ L V +K L ++V++G + +S
Sbjct: 2720 VGSEETRARVRVHD----------LHVGITK--------RLKTMEVLEGESCSFECVLSH 2761
Query: 649 NPPPE-VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 707
+ +W G + S F ++G ++ L ++E P D G E S + ++
Sbjct: 2762 ESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG----EVVFSVRGLTSK 2817
Query: 708 AVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAI--AGDPFPTVHWLRDGKALCKD 764
A L V+E +P I KP + G+ V + C + AG P VHWL+D KA+ K
Sbjct: 2818 ASLIVRE-----RPAAIIKPLEDQWVAPGEDVELRCELSRAGTP---VHWLKDRKAIRK- 2868
Query: 765 TGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
+ ++V+ + LV++ AG+Y
Sbjct: 2869 SQKYDVVCEGTMAMLVIRGASLKDAGEY 2896
Score = 100 bits (248), Expect = 2e-20
Identities = 166/761 (21%), Positives = 281/761 (36%), Gaps = 124/761 (16%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
L R + + GA A V + +VTW+++G+ ++S + ++ + T LV+
Sbjct: 1355 LAHRKVQAEAGAIATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEA-VGCTRRLVVQQA 1412
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEGS---FAKQLGQPVVSKTLGDRFSAPAVETRP 153
+ D G+Y+CEA G ++++ L V FAK+ QPV +
Sbjct: 1413 CQADTGEYSCEA----GGQRLSFSLDVAEPKVVFAKE--QPVHRE--------------- 1451
Query: 154 SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKN 213
V + G SC++ + Q +V W K L S++V +
Sbjct: 1452 ----------------VQAQAGASTTLSCEVA-QAQTEVMWYKDGKKLSFSSKVRMEAVG 1494
Query: 214 GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI---QGLDSANRSFVRETKA---T 267
+ L + Q G Y+C +G +S L + + + + + RE +A T
Sbjct: 1495 CTRRLVVQQAGQAVAGEYSC----EAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGT 1550
Query: 268 NSDVRKEVTNV------------ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315
++ + EV +S SK+ +EA ++ + G + + +
Sbjct: 1551 SATLSCEVAQAQTEVTWYKDGKKLSSSSKV-RMEAVGCTRRLVVQEAGQADAGEYSCKAG 1609
Query: 316 PPR--------ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPS 367
R E K+ K+ P + S++++ + A+ Q E G S
Sbjct: 1610 DQRLSFHLHVAEPKVVFAKEQPAHR-EVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSS 1668
Query: 368 GEERKRPAPPRPATFPTRQPGLGSQDVVS-KAANRRIPMEGQRDSAFPKFESKPQSQE-- 424
+ + A +Q G S +A +R+ P+ +P +E
Sbjct: 1669 SSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEPQISERPCRREPL 1728
Query: 425 -VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
VKE++ + ++ V W +G +RR + E +H L + A+ DS
Sbjct: 1729 VVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRH-ETASQGDTHTLTVHGAQVLDSA 1787
Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
YSC A+GQ + +QVE EVA F +L+ G L C +
Sbjct: 1788 IYSCRVG-AEGQ---DFPVQVE-----EVAAKFCRLLEPVCGELGGTVTLACEL-SPACA 1837
Query: 544 RITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
+ W ++ + E V L + ED G Y C
Sbjct: 1838 EVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVC----------------- 1880
Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
SR + S P F+ GLS + +G + T VS + V+W +G
Sbjct: 1881 ----ESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDG 1935
Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
+Q SE F Q G HSL I ++ ED G T EA ++ + A L V+E
Sbjct: 1936 ALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGAS----SSAALRVRE----AP 1987
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
F K T SV + + P+P + W R+ AL
Sbjct: 1988 VLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATAL 2027
Score = 97.4 bits (241), Expect = 1e-19
Identities = 189/859 (22%), Positives = 303/859 (35%), Gaps = 167/859 (19%)
Query: 60 PEPQVTWHRNGQPITSGGRFLLDC-GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
P P++ W RN + G + G R LV+H V DRG + CE + ++T
Sbjct: 2014 PWPELRWTRNATALAPGKNVEIHAEGAR--HRLVLHNVGFADRGFFGCETPDDKTQAKLT 2071
Query: 119 VELT-----------------------------VEGSFAKQ-------------LGQPVV 136
VE+ V+GS+ + + P+
Sbjct: 2072 VEMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMH 2131
Query: 137 SKTLGDR---------FSAPAVETRPS-IWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186
+ TL F A V T + E P F+ L VV E + C+++
Sbjct: 2132 TLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELS- 2190
Query: 187 RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
RP V WLK V L+ ++++ + + L I+ D GVY C + A SA
Sbjct: 2191 RPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC----DAHDAQSSA 2246
Query: 247 ELSIQGL------------DSANRSFVRETKATNSDVRKE---VTNVISKESKLDSLEAA 291
+ +QG D+ FV E + + +R + VT V K+ ++E
Sbjct: 2247 SVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKI-AMEKH 2305
Query: 292 AKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSP-RTAPQTPVLQKTSSSITLQAA 350
C + W SQ P K E D R + V + + T A
Sbjct: 2306 RGVLECQVSRASAQVRWFKGSQELQPGP-KYELVSDGLYRKLIISDVHAEDEDTYTCDAG 2364
Query: 351 RVQPEPR--APGLGVLSPSGEERKRPAPPRPATF------PTRQP--------------- 387
V+ + + G + P PA F P+ +P
Sbjct: 2365 DVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGN 2424
Query: 388 -GLGSQDVVSKAANRRI--PMEG--------QRDSA------FPKFESKPQSQEV-KENQ 429
GL + V + RR M G R SA P ++P + +E Q
Sbjct: 2425 VGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQ 2484
Query: 430 TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTA 489
+V C+ PK V W+ + TP+ E ++ + L +L+ D+G Y C A
Sbjct: 2485 SVVLSCDFRPAPKA-VQWYKDDTPLSPSE-KFKMSLEGQMAELRILRLMPADAGVYRCQA 2542
Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
+A S + VE V P L+D E C + + W L
Sbjct: 2543 GSAHS----STEVTVEAREVTVTGP-----LQDAEATEEGWASFSCELSHED-EEVEWSL 2592
Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
NG P+ Y S E L + + +VS SA + V K
Sbjct: 2593 NGMPL-YNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEVRVK------ 2645
Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
PV +FL+ L DL + + + +VS +P V+W +G ++ S+ +
Sbjct: 2646 ----PV--------VFLKALDDLSAEERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKY 2692
Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729
F L + +V PED G YTC G T+A + V + H G + ++
Sbjct: 2693 DFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEETRARVRVHDLHVG----ITKRLKT 2744
Query: 730 VTASLGQSVLISCAI----AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
+ G+S C + A DP W GK + + F+ + + LV+++
Sbjct: 2745 MEVLEGESCSFECVLSHESASDP---AMWTVGGKTV-GSSSRFQATRQGRKYILVVREAA 2800
Query: 786 PWHAGQYEILLKNRVGECS 804
P AG+ ++ + S
Sbjct: 2801 PSDAGEVVFSVRGLTSKAS 2819
Score = 92.8 bits (229), Expect = 3e-18
Identities = 67/245 (27%), Positives = 112/245 (45%), Gaps = 10/245 (4%)
Query: 19 VDPSRVDSMPLTEA-PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
V P + S+ ++A P F+ +N +++G F+ V G P P V W ++G+ +
Sbjct: 5111 VPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDD 5170
Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
++++ +G L+I AV D G Y C A N G EL V+ + + +
Sbjct: 5171 HYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLT-STDYDTAADA 5229
Query: 138 KTLGDRFSAPA-VETRPSIWGECP------PKFATKLGRVVVKEG-QMGRFSCKITGRPQ 189
FSA + +R E P+ +L + V G ++ +F K+ G P
Sbjct: 5230 TESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPA 5289
Query: 190 PQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELS 249
P++ W K PL SA + +++K + LEI V ++D G Y + N G A SA L
Sbjct: 5290 PRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLL 5349
Query: 250 IQGLD 254
++G D
Sbjct: 5350 VRGPD 5354
Score = 91.7 bits (226), Expect = 6e-18
Identities = 59/214 (27%), Positives = 91/214 (42%), Gaps = 15/214 (7%)
Query: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676
P AP FL V G T++ Q+ GNP P+V W + + F Q G
Sbjct: 4 PQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD 63
Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGE--------VRTQAVLTVQEPHDGTQPWFISKPR 728
+ L I ++ D+G Y C A N+ GE V +A Q PH F+ +P
Sbjct: 64 LYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH------FLLRPT 117
Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG-HFEVLQNEDVFTLVLKKVQPW 787
S+ G C + G P P V W +DG+ L + G V + + L ++ +P
Sbjct: 118 SIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPR 177
Query: 788 HAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 821
G YE+ +N +G S +L++ + +A R
Sbjct: 178 DGGTYEVRAENPLGAASAAAALVVDSDAADTASR 211
Score = 90.9 bits (224), Expect = 1e-17
Identities = 103/412 (25%), Positives = 150/412 (36%), Gaps = 37/412 (8%)
Query: 118 TVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS---IWGECPPKFATKLGRVVVKE 174
T+ + VE +Q G V + AP V P + + P F T+L V++
Sbjct: 5081 TLGIGVEIKLVEQ-GPRRVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQD 5139
Query: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTC 233
G F C +TG+P P V W K L+ ++E + G L I V D+GVY C
Sbjct: 5140 GYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRC 5199
Query: 234 LVVNGSGKASMSAELSIQ--------GLDSANRSFVRETKATNSDVRKEVTNVISKESKL 285
L N G +S AEL + D+ S + S +E T + E +L
Sbjct: 5200 LAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSREQEGTESTTDEGQL 5259
Query: 286 DSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDS-PRTAPQTPVLQKTSSS 344
+ + + R P P +L KD P TA +
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAP----RLYWFKDGQPLTASAHIRMTDKKIL 5315
Query: 345 ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIP 404
TL+ V E +S + A A R P + S + +P
Sbjct: 5316 HTLEIISVTREDSGQYAAYISNA-----MGAAYSSARLLVRGPDEPEEKPASDVHEQLVP 5370
Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTP-----VRRQEG 459
P+ + ++VK+ ++ F +V G P P V W E +
Sbjct: 5371 ---------PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTP 5421
Query: 460 SIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME 511
V A H L LL + GTY+C ASNA GQ CS +L V L +E
Sbjct: 5422 GYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473
Score = 87.0 bits (214), Expect = 2e-16
Identities = 67/233 (28%), Positives = 102/233 (43%), Gaps = 31/233 (13%)
Query: 31 EAPAFILPPRNLCIKEGAT-AKFEGRVRGYPEPQVTWHRNGQPITSGGRF-LLDCGIRGT 88
+ P + R+L + G AKF+ +V+GYP P++ W ++GQP+T+ + D I T
Sbjct: 5258 QLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHT 5317
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
++ +V ED G+Y +N GA + L V G + PA
Sbjct: 5318 LEII--SVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE--------------EKPA 5361
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV--------P 200
+ + PP+ + VK+G FS K+ GRP P V WL+ P
Sbjct: 5362 SDVHEQL---VPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGP 5418
Query: 201 LQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
P V+ S + VL V + G YTC+ N +G+A SA L + GL
Sbjct: 5419 DTPGYTVASSAQQHSLVL--LDVGRQHQGTYTCIASNAAGQALCSASLHVSGL 5469
Score = 85.1 bits (209), Expect = 6e-16
Identities = 163/756 (21%), Positives = 268/756 (35%), Gaps = 126/756 (16%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106
G A+FE V W+++G + G L + LV V +D G Y+C
Sbjct: 812 GGPAQFECET-SEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870
Query: 107 EATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATK 166
S F ++ +P V F+ + R
Sbjct: 871 RVGEDSV------------DFRLRVSEPKVV------FAKEQLARR-------------- 898
Query: 167 LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226
++ + G SC++ + Q +VTW K L S++V + + L + Q
Sbjct: 899 --KLQAEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQA 955
Query: 227 DVGVYTCLVVNGSGKASMSAELSIQ------GLDSANRSFVRETKATNSDVRKEVTNVIS 280
D G Y+C +G +S L ++ D S V+ ++ + EV +
Sbjct: 956 DAGEYSC----EAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQT 1011
Query: 281 -----KESKL--DSLEAAAKSKNCSS----PQRGGSPPWAANSQPQPPRES-KLESCKDS 328
K+ K SL+ ++K C Q G + + + + R S +L +
Sbjct: 1012 EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPK 1071
Query: 329 PRTAPQTPVLQKT------SSSITLQAARVQPEPR--APGLGVLSPSGEERKRPAPPRPA 380
A + V + S+ ++ + A+ Q E G + S S + R
Sbjct: 1072 MMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRL 1131
Query: 381 TFPTRQPGLGSQDVVS-KAANRRIPME---GQRDSAFPKFESKPQSQEVKENQTVKFRCE 436
P Q G S +A +R+ + F K +S + + T CE
Sbjct: 1132 VLP--QAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCE 1189
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
V+ P+ EV W+ +G + + + + L + + D+G YSC A +
Sbjct: 1190 VAQ-PQTEVTWYKDGKKLS-SSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSF 1247
Query: 497 SCSWTLQVERLAVMEVAPSFSS---VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553
+L + E F+ V + G L C V +TW +G+
Sbjct: 1248 ---------QLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKK 1297
Query: 554 IQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
+ + R + +L +Q A D G YTC A ++
Sbjct: 1298 LSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA-------------------GGQRLS 1338
Query: 611 YLLPVAPSKPTAPIFLQGLSDLKVMD--GSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668
+ L V S+P A + L+ KV G+ T++ +V+ EV W +G ++ S
Sbjct: 1339 FHLDV--SEPKAVFAKEQLAHRKVQAEAGAIATLSCEVA-QAQTEVTWYKDGKKLSSSSK 1395
Query: 669 FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---HDGTQPWFIS 725
E G L +Q+ DTG Y+CE AG R L V EP QP
Sbjct: 1396 VRMEAVGCTRRLVVQQACQADTGEYSCE----AGGQRLSFSLDVAEPKVVFAKEQP---- 1447
Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
R V A G S +SC +A V W +DGK L
Sbjct: 1448 VHREVQAQAGASTTLSCEVA-QAQTEVMWYKDGKKL 1482
Score = 82.8 bits (203), Expect = 3e-15
Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 32/239 (13%)
Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
+D + AP F+ P+ + G A ++ G P PQV+W ++ QP+ +G RF L
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRL-A 59
Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
+ L I + D G+Y C A N G V L V+ A
Sbjct: 60 QDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAA--------------- 104
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL-Q 202
E P F + + V+EG F C++ G P+P V+W K L +
Sbjct: 105 ------------CAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGE 152
Query: 203 PSA-RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI--QGLDSANR 258
P RV V E L I D G Y N G AS +A L + D+A+R
Sbjct: 153 PDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASR 211
Score = 82.8 bits (203), Expect = 3e-15
Identities = 166/799 (20%), Positives = 279/799 (34%), Gaps = 143/799 (17%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE--E 99
+C KE +A VR P + RN + T G L C + + HE
Sbjct: 3697 MCGKERTSAMLT--VRAMPSKFIEGLRN-EEATEGDTATLWCELSKAAPVEWRKGHETLR 3753
Query: 100 DRGKYTCEATNGSGARQVTVELTVE-GSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
D +++ Q+ V+ G ++ GQ S TL R
Sbjct: 3754 DGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVR--------------A 3799
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
P +F + +EG C+++ V W KG+ L+ R S+ + L
Sbjct: 3800 LPARFIEDVKNQEAREGATAVLQCELS--KAAPVEWRKGSETLRGGDRYSLRQDGTRCEL 3857
Query: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV 278
+IHG++ D G Y+C+ G+ SA L++ +A R+ + ++
Sbjct: 3858 QIHGLSVADTGEYSCV----CGQERTSATLTV--------------RAPQPVFREPLQSL 3899
Query: 279 ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESC----------KDS 328
++E +L+ + G AN + RE +L+ C ++
Sbjct: 3900 QAEEGSTATLQCELSEPTATVVWSKGGLQLQANGR----REPRLQGCTAELVLQDLQRED 3955
Query: 329 PRTAPQTPVLQKTSSSITLQAARV------QPEPRAPG--------LGVLSPSGEERKRP 374
T Q TS+++T+ AA V Q + G L S E RK
Sbjct: 3956 TGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGS 4015
Query: 375 APPRP-ATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF-----------------PKF 416
P A + Q G ++ +V R + E D PKF
Sbjct: 4016 LQLFPCAKYQMVQDGAAAELLV-----RGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKF 4070
Query: 417 ESKPQSQEVKENQTVKFRCEVSGIPKPEVA-WFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
+++ QS E + + C++S V W EG + E+ + L +
Sbjct: 4071 KTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGP-KYEMRSQGATRELLIH 4129
Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
+ +D+G Y+C + S L V E + L D V +D C
Sbjct: 4130 QLEAKDTGEYACVTGGQKTAAS---------LRVTEPEVTIVRGLVDAEVTADEDVEFSC 4180
Query: 536 SVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-----LHIQDALPEDHGTYTCLAENALG 590
V + W L G P+Q + E V + L ++ PED GT + LG
Sbjct: 4181 EVSRAGATGVQWCLQGLPLQ-SNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSF----HLG 4235
Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
+ SA +TV + + L+ L D+++ +G + ++S
Sbjct: 4236 NHASSAQLTVRAPEVT------------------ILEPLQDVQLSEGQDASFQCRLSRAS 4277
Query: 651 PPEVIWLHNGNEIQESE--DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 708
E W G +Q +E D EQ GT H L + +V ED GT + + E + +
Sbjct: 4278 GQEARWALGGVPLQANEMNDITVEQ-GTLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKV 4336
Query: 709 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGH 767
+ + +V A G L C ++ WL D + + +
Sbjct: 4337 T---------AKNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAE 4387
Query: 768 FEVLQNEDVFTLVLKKVQP 786
+N L+LK ++P
Sbjct: 4388 VVFFENGLRHLLLLKNLRP 4406
Score = 82.0 bits (201), Expect = 5e-15
Identities = 55/199 (27%), Positives = 87/199 (43%), Gaps = 9/199 (4%)
Query: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLC 681
P F + L+D G V + +V+G P P + W +G +Q + E +L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
+ + D+G Y C A ++AG T + VQ P P F++K R+ G+ +
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 6128
Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ--NEDVFTLVLKKVQPWHAGQYEILLKNR 799
C I G P+P + W +DG AL F+ L + LV++ G YE L NR
Sbjct: 6129 CTIEGAPYPQIRWYKDG-ALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187
Query: 800 VGECSCQVSLMLQNSSARA 818
+G L +Q+ +A
Sbjct: 6188 LGSARASAELRIQSPMLQA 6206
Score = 79.3 bits (194), Expect = 3e-14
Identities = 156/687 (22%), Positives = 265/687 (38%), Gaps = 117/687 (17%)
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
+ +V W+++G+ ++ + ++ + T LV+ + G+Y+CEA G+++++
Sbjct: 1470 QTEVMWYKDGKKLSFSSKVRMEA-VGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFH 1524
Query: 121 LTV---EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQM 177
L V + FAK+ QP + V + G
Sbjct: 1525 LHVAEPKAVFAKE--QPASRE-------------------------------VQAEAGTS 1551
Query: 178 GRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVN 237
SC++ + Q +VTW K L S++V + + L + Q D G Y+C
Sbjct: 1552 ATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA-- 1608
Query: 238 GSGKASMSAELSIQGL-----DSANRSFVRETKAT---NSDVRKEVTNV--------ISK 281
G + S ++ + A+R E A+ + +V + T V +S
Sbjct: 1609 GDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSS 1668
Query: 282 ESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES------KLESCKDSPRTAPQT 335
SK+ +EA ++ Q G + + + R S +LE + S R +
Sbjct: 1669 SSKV-RVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEP-QISERPCRRE 1726
Query: 336 PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGL-GSQDV 394
P++ K I L A P A + L E R+ + T + G+Q +
Sbjct: 1727 PLVVKEHEDIILTATLATPS--AATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVL 1784
Query: 395 VSKAANRRIPMEGQR-----DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFL 449
S + R+ EGQ + KF + + TV CE+S EV W
Sbjct: 1785 DSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACA-EVVWRC 1843
Query: 450 EGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509
T +R + ++ + L +L R D+G Y C + + S T+ V R+
Sbjct: 1844 GNTQLRVGK-RFQMVAEGPVRSLTVLGLRAEDAGEYVCESRD--DHTSAQLTVSVPRVV- 1899
Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR--STCEAGVAE 567
F S L EG + QC V + V + W +G +Q + + ++G +
Sbjct: 1900 -----KFMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQPSEKFAISQSGASH 1953
Query: 568 -LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626
L I D + ED G T AE A S SA + V E PV +F
Sbjct: 1954 SLTISDLVLEDAGQITVEAEGA----SSSAALRVREA----------PV--------LFK 1991
Query: 627 QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF 686
+ L V + S VT+ V+++ P PE+ W N + ++ G +H L + V
Sbjct: 1992 KKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVG 2050
Query: 687 PEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
D G + CE + +TQA LTV+
Sbjct: 2051 FADRGFFGCE----TPDDKTQAKLTVE 2073
Score = 79.0 bits (193), Expect = 4e-14
Identities = 62/250 (24%), Positives = 112/250 (44%), Gaps = 13/250 (5%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILS--QEGSLCS 1154
AP F +LQ+ V +G + C V+ P ++ W +GK L+ +++ Q+G
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG-HQ 5183
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
+ I +P D G+Y+C+A+N G + ++ VD +T A +S S+ +
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243
Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTGTQPITCTWMK 1273
E + T ++ PQ+++ D +V G + F KV G W K
Sbjct: 5244 SREQEGT-------ESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296
Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
+ + S H+++ + + L I++ +E G Y + N +G+ + L +V PD
Sbjct: 5297 DGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL-LVRGPDE 5355
Query: 1334 PAGTPCASDI 1343
P P ASD+
Sbjct: 5356 PEEKP-ASDV 5364
Score = 78.2 bits (191), Expect = 7e-14
Identities = 153/756 (20%), Positives = 264/756 (34%), Gaps = 107/756 (14%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
L R L + GA+A V + +VTW+++G+ ++S + ++ T LV+
Sbjct: 895 LARRKLQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEA-TGCTRRLVVQQA 952
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIW 156
+ D G+Y+CEA G ++++ L V+ +P V
Sbjct: 953 GQADAGEYSCEA----GGQRLSFHLDVK--------EPKVVFA----------------- 983
Query: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
K V + G SC++ + Q +V W K L S +V V K +
Sbjct: 984 -----KDQVAHSEVQAEAGASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVEAKGCRR 1037
Query: 217 VLEIHGVNQDDVGVYTCLVVN---------GSGKASMSAELSIQGLDSANRSFVRETKAT 267
L + + D G Y+C K + E S+ A
Sbjct: 1038 RLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCE 1097
Query: 268 NSDVRKEVT-----NVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES-K 321
+ + EVT +S SK+ +E ++ PQ G + + + R S
Sbjct: 1098 VAQAQTEVTWYKDGKKLSSSSKV-GMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFH 1156
Query: 322 LESCKDSPRTAPQTPVLQK------TSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPA 375
L + A + V + T++ ++ + A+ Q E G S + +
Sbjct: 1157 LHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEV 1216
Query: 376 PPRPATFPTRQPGLGSQDVVS-KAANRRIPME---GQRDSAFPKFESKPQSQEVKENQTV 431
+Q G S +A +R+ + + + F K + + +
Sbjct: 1217 KGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASA 1276
Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
CEV+ + EV W+ +G + + + L + +A D+G Y+C A
Sbjct: 1277 TLSCEVAQ-AQTEVTWYKDGKKL-SSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEAGG 1334
Query: 492 AQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551
+LS + + + + V + I L C V +TW +G
Sbjct: 1335 Q--RLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIA----TLSCEVAQAQT-EVTWYKDG 1387
Query: 552 QPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 608
+ + + R L +Q A D G Y+C A ++
Sbjct: 1388 KKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA-------------------GGQR 1428
Query: 609 SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668
+ L VA K +++ G+ T++ +V+ EV+W +G ++ S
Sbjct: 1429 LSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVA-QAQTEVMWYKDGKKLSFSSK 1487
Query: 669 FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---HDGTQPWFIS 725
E G L +Q+ G Y+CE AG R L V EP QP
Sbjct: 1488 VRMEAVGCTRRLVVQQAGQAVAGEYSCE----AGSQRLSFHLHVAEPKAVFAKEQP---- 1539
Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
R V A G S +SC +A V W +DGK L
Sbjct: 1540 ASREVQAEAGTSATLSCEVA-QAQTEVTWYKDGKKL 1574
Score = 78.2 bits (191), Expect = 7e-14
Identities = 172/822 (20%), Positives = 308/822 (37%), Gaps = 150/822 (18%)
Query: 60 PEPQ-VTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRGKYTCEATNGSGARQV 117
P P+ V W+++ P++ +F + + G + L I + D G Y C+A + + +V
Sbjct: 2494 PAPKAVQWYKDDTPLSPSEKFKMS--LEGQMAELRILRLMPADAGVYRCQAGSAHSSTEV 2551
Query: 118 TVE---LTVEG-------------SFAKQL------------GQPVVSKTLGD------- 142
TVE +TV G SF+ +L G P+ + + +
Sbjct: 2552 TVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRR 2611
Query: 143 ----------------RFSAPAVETRPSIWGECPPK-FATKLGRVVVKEGQMGRFSCKIT 185
R S+ V T + P F L + +E C+++
Sbjct: 2612 HTLVLKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS 2671
Query: 186 GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245
P+ V W K V L PS + G + L +H V+ +D G+YTC V G
Sbjct: 2672 D-PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHV----GSEETR 2726
Query: 246 AELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRG-- 303
A + + L + + K + + E + S E ++ S P
Sbjct: 2727 ARVRVHDL--------------HVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTV 2772
Query: 304 GSPPWAANSQPQPPRESK---LESCKDSPRTAPQTPV----LQKTSSSITLQ--AARVQP 354
G ++S+ Q R+ + L + +P A + L +S I + AA ++P
Sbjct: 2773 GGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKP 2832
Query: 355 ---EPRAPGLGV-----LSPSGEE----RKRPAPPRPATFPTRQPGLGSQDVVSKAANR- 401
+ APG V LS +G + R A + + G + V+ A+ +
Sbjct: 2833 LEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKD 2892
Query: 402 ----RIPMEGQRDSAFPKFESKPQ-------SQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
+E + +A E K + +V+E T F C+ P V W +
Sbjct: 2893 AGEYTCEVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTW-RK 2950
Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510
G R G + ++ + L + DS TY+C AQ + +Q R+ ++
Sbjct: 2951 GLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQL--LVQGRRVHII 3008
Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI 570
E L+D V EG +C + + W L+ P+ EL+
Sbjct: 3009 ED-------LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLH---------ANELNE 3052
Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
DA P G Y L L Q++ T++ + +++ L V KP+ +F + L+
Sbjct: 3053 IDAQP---GGYHVL---TLRQLALKDSGTIYFEAGDQRASAALRVT-EKPS--VFSRELT 3103
Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
D + +G +T+ + S P V W +G ++ S G + L I +D+
Sbjct: 3104 DATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDS 3162
Query: 691 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFP 750
G Y CE AG + +++ V F + + G + + C ++ P
Sbjct: 3163 GRYKCE----AGGACSSSIVRVH----ARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP 3214
Query: 751 TVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
V W G + + + + Q + LV++ ++P +G+Y
Sbjct: 3215 -VKWCY-GNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRY 3254
Score = 76.6 bits (187), Expect = 2e-13
Identities = 65/234 (27%), Positives = 97/234 (41%), Gaps = 43/234 (18%)
Query: 23 RVDSMPLTEAPAFILPP----RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
R ++M APA PP R + EG A+ V G P+P+ W ++GQ +T G R
Sbjct: 226 RREAMRAEGAPAS--PPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR 283
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
++ + F L I + DRG YTC A+N G +V + V
Sbjct: 284 HVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR-------------- 329
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
PAV F +L + V+E + F C++ +P + W K
Sbjct: 330 -------EPAVP------------FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEE 369
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252
L SA+ + E+ + L + V+ DD VY C GS AEL++QG
Sbjct: 370 TRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTV---AELAVQG 420
Score = 75.9 bits (185), Expect = 3e-13
Identities = 156/751 (20%), Positives = 273/751 (36%), Gaps = 117/751 (15%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC-GIRGTFSLVIHAVHEEDRGKYT 105
GA+A V + +V W+++G+ ++S + ++ G R LV+ + D G Y+
Sbjct: 997 GASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRR--LVVQQAGKTDAGDYS 1053
Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFAT 165
CEA G R S T P + K +
Sbjct: 1054 CEAR-------------------------------GQRVSFRLHITEPKMMFA---KEQS 1079
Query: 166 KLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQ 225
V + G SC++ + Q +VTW K L S++V + K + L + +
Sbjct: 1080 VHNEVQAEAGASAMLSCEVA-QAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGK 1138
Query: 226 DDVGVYTCLVVNGSGKASMSAELSI---QGLDSANRSFVRETKAT-------NSDVRKEV 275
D G Y+C +G +S L I +G+ + +S E +A + +V +
Sbjct: 1139 ADAGEYSC----EAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQ 1194
Query: 276 TNV--------ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCK 326
T V +S SK+ +E ++ Q G + + + R S +L +
Sbjct: 1195 TEVTWYKDGKKLSSSSKV-RMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITE 1253
Query: 327 DSPRTAPQTPVLQKT------SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPA 380
A + V + S++++ + A+ Q E G S + + A
Sbjct: 1254 PKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMR 1313
Query: 381 TFPTRQPGLGSQ-DVVSKAANRRIPME---GQRDSAFPKFESKPQSQEVKENQTVKFRCE 436
+Q G + +A +R+ + + F K + + + + CE
Sbjct: 1314 QLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCE 1373
Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
V+ + EV W+ +G + + + + L + +A D+G YSC A + L
Sbjct: 1374 VAQA-QTEVTWYKDGKKLS-SSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQR--L 1429
Query: 497 SCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY 556
S S + ++ + P V ++ G L C V + W +G+ + +
Sbjct: 1430 SFSLDVAEPKVVFAKEQP----VHREVQAQAGASTTLSCEVAQAQT-EVMWYKDGKKLSF 1484
Query: 557 ARSTCEAGVA---ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 613
+ V L +Q A G Y+C A S++ + L
Sbjct: 1485 SSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA-------------------GSQRLSFHL 1525
Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673
VA K +++ G+ T++ +V+ EV W +G ++ S E
Sbjct: 1526 HVAEPKAVFAKEQPASREVQAEAGTSATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEA 1584
Query: 674 RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---HDGTQPWFISKPRSV 730
G L +QE D G Y+C+ AG+ R L V EP QP R V
Sbjct: 1585 VGCTRRLVVQEAGQADAGEYSCK----AGDQRLSFHLHVAEPKVVFAKEQP----AHREV 1636
Query: 731 TASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
A G S +SC +A V W +DGK L
Sbjct: 1637 QAEAGASATLSCEVA-QAQTEVTWYKDGKKL 1666
Score = 75.5 bits (184), Expect = 5e-13
Identities = 161/754 (21%), Positives = 264/754 (35%), Gaps = 184/754 (24%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG-TFSL 91
P F P ++L +EG+TA + + P V W + G + + GR + ++G T L
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGR--REPRLQGCTAEL 3946
Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVTVELTV---------------------------- 123
V+ + ED G+YTC T GS A T+ +T
Sbjct: 3947 VLQDLQREDTGEYTC--TCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSR 4004
Query: 124 ------------------------EGSFAKQLGQPVVSKTLGD-RFSAPAVETRPSIWGE 158
+G+ A+ L + V + GD ++ S+
Sbjct: 4005 AGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVR 4064
Query: 159 CP-PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVT-WLKGNVPLQPSARVSVSEKNGMQ 216
P PKF T+L + + G + R C+++ V WLK V L + + + +
Sbjct: 4065 VPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATR 4124
Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVT 276
L IH + D G Y C V G K + S +R T+ + VR V
Sbjct: 4125 ELLIHQLEAKDTGEYAC--VTGGQKTAAS---------------LRVTEPEVTIVRGLVD 4167
Query: 277 NVISKESKLDSLEAAAKSKNCSSPQRGGS-PPWAANSQPQPPRESKLESCKD----SPRT 331
++ + ++ +C + G + W P E + +D + R
Sbjct: 4168 AEVTADEDVEF--------SCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRL 4219
Query: 332 APQTPVLQKT-SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLG 390
TP T S + A+ Q RAP + +L P
Sbjct: 4220 KGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEP------------------------ 4255
Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
QDV EGQ D++F S+ QE R + G+P
Sbjct: 4256 LQDVQLS--------EGQ-DASFQCRLSRASGQEA--------RWALGGVP--------- 4289
Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510
++ E + E H L L K D+GT S +CS Q++ A
Sbjct: 4290 ---LQANEMNDITVEQGTLHLLTLHKVTLEDAGTVSFHVG------TCSSEAQLKVTAKN 4340
Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST----CEAGVA 566
V L++ +EG + + +C + V TWLL+ +P+ + + E G+
Sbjct: 4341 TVVRG----LENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLR 4396
Query: 567 E-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIF 625
L +++ P+D T LA G + SA++TV +
Sbjct: 4397 HLLLLKNLRPQDSCRVTFLA----GDMVTSAFLTVRGWRLE------------------I 4434
Query: 626 LQGLSDLKVMDGSQVTMTVQVS-GNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLCIQ 683
L+ L + V G+Q T +S P E W NG +Q + D+ G+ H+L ++
Sbjct: 4435 LEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLR 4494
Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
P G T ++ R + P D
Sbjct: 4495 SAQPHHAGEVTFACRDAVASARLTVLGLPDPPED 4528
Score = 73.6 bits (179), Expect = 2e-12
Identities = 107/500 (21%), Positives = 181/500 (36%), Gaps = 101/500 (20%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR-VSVSEKNGMQVL 218
PP F +L + G+ + +C++TG P+P ++W K +Q + + + +G L
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT----NSDVRKE 274
+ + D G Y C + +G S ++ +Q FV + +A+ D +
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----VPPRFVNKVRASPFVEGEDAQFT 6128
Query: 275 VT---------------NVISKESKLDSLE------------AAAKSK----NCSSPQRG 303
T +++ +K +L AA+K C R
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188
Query: 304 GSPPWAANSQPQPPRESKLESC-KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLG 362
GS +A + Q P E C ++ A + L++ +T R+ P+APG
Sbjct: 6189 GSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTSVLKRLLG-PKAPG-- 6245
Query: 363 VLSPSGEERKRPAP-PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
PS + P P PR A P Q V + +P + E +P+
Sbjct: 6246 ---PSTGDLTGPGPCPRGA--PALQETGSQPPVTGTSEAPAVPPRVPQPLLHEGPEQEPE 6300
Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481
+ + TV R E + P G+ E+ D SH +++ T+
Sbjct: 6301 AIARAQEWTVPIRMEGAAWPGA---------------GTGELLWDVHSH---VVRETTQR 6342
Query: 482 SGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTP 541
+ TY ++ PS ++D G + + G P
Sbjct: 6343 TYTYQAIDTHTARP------------------PSMQVTIEDVQAQTGGTAQFEAIIEGDP 6384
Query: 542 VPRITWLLNGQPIQYARSTC-----EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
P +TW + +Q ST E L ++ +D G YTCLA+N GQV C A
Sbjct: 6385 QPSVTWYKDS--VQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKA 6442
Query: 597 WVTV--------HEKKSSRK 608
+ V EK+S R+
Sbjct: 6443 ELLVLGGDNEPDSEKQSHRR 6462
Score = 71.2 bits (173), Expect = 9e-12
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F +++ EV +G FDC + G P P V WFKD + + E H+ I+ D+ G LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
I+ V D Y C A NS+G ++ AEL V+
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217
Score = 68.6 bits (166), Expect = 6e-11
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
E K P FS T D E G A R +C + D W KD + + RH ID
Sbjct: 4891 EMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG 4950
Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 1862
DG CSL+I+ + D YTC+ N G+ T +A ++V E+ E GE ++
Sbjct: 4951 DGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDD 5005
Score = 68.2 bits (165), Expect = 7e-11
Identities = 138/635 (21%), Positives = 245/635 (38%), Gaps = 100/635 (15%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
P +F KL EG C+++ V W KG+ L+ R + + M L+
Sbjct: 3273 PAQFIGKLRNKEATEGATATLRCELS--KAAPVEWRKGSETLRDGDRYCLRQDGAMCELQ 3330
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I G+ D Y+C+ G+ SA L+I+ + + F+ + S + +
Sbjct: 3331 IRGLAMVDAAEYSCV----CGEERTSASLTIRPMPA---HFIGRLRHQES-IEGATATLR 3382
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVL- 338
+ SK +E ++ R +S Q +L+ C + A + +
Sbjct: 3383 CELSKAAPVEWRKGRESLRDGDR--------HSLRQDGAVCELQICGLAVADAGEYSCVC 3434
Query: 339 --QKTSSSITLQA------ARVQPEPRAPG--------LGVLSPSGEERKRPAPPRPA-T 381
++TS+++T++A ++ E G L ++P E RK P R
Sbjct: 3435 GEERTSATLTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAPV-EWRKGPENLRDGDR 3493
Query: 382 FPTRQPGLGSQ----DVVSKAANRRIPMEGQ-RDSAFPKFESKPQS--QEVKENQ----- 429
+ RQ G + + A + + GQ R SA + P ++VK +
Sbjct: 3494 YILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPARFIEDVKNQEAREGA 3553
Query: 430 TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTA 489
T +CE++ E + +G+ R + +D L + D+G YSC
Sbjct: 3554 TAVLQCELNSAAPVE---WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVC 3610
Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
GQ S L V L + F+ L++ EG VL+C + + + + W
Sbjct: 3611 ----GQERTSAMLTVRALPI-----KFTEGLRNEEATEGATAVLRCEL--SKMAPVEWWK 3659
Query: 550 NGQPIQYA--RSTCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS 606
+ ++ S + G EL I+ + ED G Y C+ G+ SA +TV
Sbjct: 3660 GHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVR----- 3710
Query: 607 RKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES 666
PSK F++GL + + +G T+ ++S P E W +++
Sbjct: 3711 --------AMPSK-----FIEGLRNEEATEGDTATLWCELSKAAPVE--WRKGHETLRDG 3755
Query: 667 EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK 726
+ Q G++ L I+ + D G Y+C G+ RT A LTV+ FI
Sbjct: 3756 DRHSLRQDGSRCELQIRGLAVVDAGEYSC----VCGQERTSATLTVR----ALPARFIED 3807
Query: 727 PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
++ A G + ++ C ++ V W + + L
Sbjct: 3808 VKNQEAREGATAVLQCELS--KAAPVEWRKGSETL 3840
Score = 67.4 bits (163), Expect = 1e-10
Identities = 60/243 (24%), Positives = 96/243 (39%), Gaps = 22/243 (9%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
AP F + + V EG + +C+V P + W+ +G+ L + + + G +
Sbjct: 109 APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168
Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
+ I A P D G Y+ A+N G A + + VD A + RP +S +L
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAAD--------TASRPGTSTAALL 220
Query: 1215 G--TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
++ + AP +PP V G+ L VTG W
Sbjct: 221 AHLQRRREAMRAEGAPASPPSTG--------TRTCTVTEGKHARLSCYVTGEPKPETVWK 272
Query: 1273 KFRKQIQES-EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
K + + E H+ E+++ L IL +Q G YT N +G + V L VV +P
Sbjct: 273 KDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVVVREP 331
Query: 1332 DPP 1334
P
Sbjct: 332 AVP 334
Score = 67.0 bits (162), Expect = 2e-10
Identities = 62/229 (27%), Positives = 82/229 (35%), Gaps = 25/229 (10%)
Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
KF+ +V G P P + WF +G P+ I + + H L ++ DSG Y+ SN
Sbjct: 5279 KFQLKVKGYPAPRLYWFKDGQPL-TASAHIRMTDKKILHTLEIISVTREDSGQYAAYISN 5337
Query: 492 AQGQLSCSWTLQVERLAVME-----------VAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
A G S L V E V P V +G V G
Sbjct: 5338 AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR 5397
Query: 541 PVPRITWLLN---------GQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
PVP + WL G A L + D + GTYTC+A NA GQ
Sbjct: 5398 PVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 5457
Query: 592 VSCSAWVTV----HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
CSA + V ++ + E L+ T I QGL D
Sbjct: 5458 ALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQGLETASFAD 5506
Score = 65.5 bits (158), Expect = 5e-10
Identities = 46/151 (30%), Positives = 68/151 (45%), Gaps = 13/151 (8%)
Query: 114 ARQVTVELTVEGSFAKQLG---------QPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
A++ TV + +EG+ G VV +T ++ A++T + PP
Sbjct: 6305 AQEWTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQAIDTHTAR----PPSMQ 6360
Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
+ V + G +F I G PQP VTW K +V L S R+S ++ L + V
Sbjct: 6361 VTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVA 6420
Query: 225 QDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
D GVYTCL N G+ AEL + G D+
Sbjct: 6421 SKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 6451
Score = 63.9 bits (154), Expect = 1e-09
Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P TI D++ G A+F+ IEG P P V W+KD + +S E SL+
Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLS-QQQEGTTYSLV 6415
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
+ V D YTC A N+ G+ C AEL+V G+ E + E++
Sbjct: 6416 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV---LGGDNEPDSEKQ 6458
Score = 63.5 bits (153), Expect = 2e-09
Identities = 25/92 (27%), Positives = 49/92 (53%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F + + D G + C++ G P P + W+KD ++++ H + D DG+C+LI
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+ + G D +Y C A ++ G + +++V+
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ 6105
Score = 62.0 bits (149), Expect = 5e-09
Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ-IDYDEDGNC 1814
V P F +R VEG A+F C IEG P P++ W+KD + FQ + G
Sbjct: 6106 VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL 6165
Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1850
L+I +D Y C+ VN LG A +AEL +++
Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201
Score = 61.2 bits (147), Expect = 9e-09
Identities = 75/376 (19%), Positives = 137/376 (36%), Gaps = 38/376 (10%)
Query: 413 FPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472
F K + + + + + CEV+ + EV W+ +G + + + + L
Sbjct: 1442 FAKEQPVHREVQAQAGASTTLSCEVAQA-QTEVMWYKDGKKLSFSS-KVRMEAVGCTRRL 1499
Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
+ +A +G YSC A + + LS + + + P+ V + G
Sbjct: 1500 VVQQAGQAVAGEYSCEAGSQR--LSFHLHVAEPKAVFAKEQPASREVQAEA----GTSAT 1553
Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA---ELHIQDALPEDHGTYTCLAENAL 589
L C V +TW +G+ + + V L +Q+A D G Y+C
Sbjct: 1554 LSCEVAQAQT-EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSC------ 1606
Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
K ++ + L VA K +++ G+ T++ +V+
Sbjct: 1607 -------------KAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVA-Q 1652
Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
EV W +G ++ S E G L +Q+ D G Y+CEA R
Sbjct: 1653 AQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLH-- 1710
Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
+ EP +P + + + ++++ +A TV WL+DG + + H E
Sbjct: 1711 VAELEPQISERP---CRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRH-E 1766
Query: 770 VLQNEDVFTLVLKKVQ 785
D TL + Q
Sbjct: 1767 TASQGDTHTLTVHGAQ 1782
Score = 61.2 bits (147), Expect = 9e-09
Identities = 86/385 (22%), Positives = 152/385 (39%), Gaps = 62/385 (16%)
Query: 416 FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
F + + QE E T RCE+S E + +G R + +D L +
Sbjct: 3364 FIGRLRHQESIEGATATLRCELSKAAPVE---WRKGRESLRDGDRHSLRQDGAVCELQIC 3420
Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
D+G YSC G+ S TL V+ L F+ L++ +EG +L C
Sbjct: 3421 GLAVADAGEYSCVC----GEERTSATLTVKALPA-----KFTEGLRNEEAVEGATAMLWC 3471
Query: 536 SVRGTPVPRITW------LLNGQP--IQYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587
+ + V + W L +G ++ + CE + L + DA G Y C+
Sbjct: 3472 EL--SKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADA-----GEYLCVC-- 3522
Query: 588 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
GQ SA +T+ LP F++ + + + +G+ + +++
Sbjct: 3523 --GQERTSATLTIRA----------LPAR--------FIEDVKNQEAREGATAVLQCELN 3562
Query: 648 GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 707
P E W +++ + + Q GT+ L I+ + DTG Y+C G+ RT
Sbjct: 3563 SAAPVE--WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSC----VCGQERTS 3616
Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
A+LTV+ F R+ A+ G + ++ C ++ V W + G +D
Sbjct: 3617 AMLTVR----ALPIKFTEGLRNEEATEGATAVLRCELS--KMAPVEWWK-GHETLRDGDR 3669
Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQY 792
+ Q+ L ++ + AG+Y
Sbjct: 3670 HSLRQDGARCELQIRGLVAEDAGEY 3694
Score = 61.2 bits (147), Expect = 9e-09
Identities = 82/341 (24%), Positives = 117/341 (34%), Gaps = 35/341 (10%)
Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR---- 558
+V + + P FS D G L+C V R WL +G + R
Sbjct: 4887 KVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHI 4946
Query: 559 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
G L I D G YTC N GQV+ SA V V +S +S + +
Sbjct: 4947 DQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDA 5006
Query: 619 KPTAPIFLQGL----SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF---HF 671
A L L S +V D + P W +E E F F
Sbjct: 5007 FRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADW----QTYREDEHFICIRF 5062
Query: 672 EQ--RGTQHSLCIQEVFPE----------DTGTYTCEAWNSAGEVRTQAVLTVQEP---- 715
E Q QE+F + G E S T A + EP
Sbjct: 5063 EALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISK---ETPAPVVPPEPLPSL 5119
Query: 716 -HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNE 774
P F+++ ++ G V C + G P P+V W +DGK L +D + +
Sbjct: 5120 LTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQ 5179
Query: 775 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSS 815
L++ V P G Y L +N +G S + L + +S
Sbjct: 5180 GGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTS 5220
Score = 60.5 bits (145), Expect = 2e-08
Identities = 56/262 (21%), Positives = 103/262 (39%), Gaps = 39/262 (14%)
Query: 1079 RGHAGTTDNE--KRSESQGTAPAFKQKLQDVHVAEGKKLL-LQCQVSSDPPATIIWTLNG 1135
+G+ + + E + + +G P ++L+D+ VA G +L Q +V P + W +G
Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDG 5298
Query: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195
+ L + I ++ + L ++ I ED G Y N G A S ++ V
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV-------- 5350
Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
+ P+ +P S + L +PP++++ +KV+ G S+
Sbjct: 5351 -RGPDEPEEKPASDVHEQL---------------------VPPRMLERFTPKKVKKGSSI 5388
Query: 1256 ELFGKVTGTQPITCTWMKFRKQI------QESEHMKVENSENGSKLTILAARQEHCGCYT 1309
KV G T W++ + ++ V +S L +L ++H G YT
Sbjct: 5389 TFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYT 5448
Query: 1310 LLVENKLGSRQAQVNLTVVDKP 1331
+ N G +L V P
Sbjct: 5449 CIASNAAGQALCSASLHVSGLP 5470
Score = 59.7 bits (143), Expect = 3e-08
Identities = 58/247 (23%), Positives = 88/247 (35%), Gaps = 42/247 (17%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
AP F + + V+ GK L CQ+ +P + W + + + L+Q+G L ++
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLT 68
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
I D G Y C A+N G+A + + VD A
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAAC----------------------- 105
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
A P + P +VR G +V G+ +W K +
Sbjct: 106 -----------------AEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGR 148
Query: 1277 QIQESE--HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
++ E + ++VE S L I AAR G Y + EN LG+ A L V
Sbjct: 149 RLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADT 208
Query: 1335 AGTPCAS 1341
A P S
Sbjct: 209 ASRPGTS 215
Score = 59.7 bits (143), Expect = 3e-08
Identities = 78/327 (23%), Positives = 132/327 (40%), Gaps = 49/327 (14%)
Query: 394 VVSKAANRRIPMEGQRDSAFPK-------FESKPQSQEVKENQTVKFRCEVSGIPKPEVA 446
V+ A + EG SA + F+ K + Q V+E +V E++ P PE+
Sbjct: 1961 VLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTR-PWPELR 2019
Query: 447 WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
W T + + ++E++ + H L L D G + C + + Q T+++ +
Sbjct: 2020 WTRNATALAPGK-NVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQ--AKLTVEMRQ 2076
Query: 507 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA 566
+ ++ + + + A +E Q + V G +W +G Q TC V
Sbjct: 2077 VRLVRGLQAVEAREQGTATMEVQ--LSHADVDG------SWTRDGLRFQQG-PTCHLAVR 2127
Query: 567 ----ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622
L + PED G AE V SA + V E LPV+ S+P
Sbjct: 2128 GPMHTLTLSGLRPEDSGLMVFKAEG----VHTSARLVVTE----------LPVSFSRP-- 2171
Query: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682
L D+ + +VT+ ++S P +V WL +G E++ + +G SL I
Sbjct: 2172 ------LQDVVTTEKEKVTLECELS-RPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTI 2224
Query: 683 QEVFPEDTGTYTCEAWN--SAGEVRTQ 707
D G Y C+A + S+ V+ Q
Sbjct: 2225 YRCEFADQGVYVCDAHDAQSSASVKVQ 2251
Score = 59.7 bits (143), Expect = 3e-08
Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
Query: 1758 PYFSKTIRDLEVVEGSA-ARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
P + +RDL+V G+ A+F K++GYP P + WFKD Q + S H ++ D+ +L
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTL 5318
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
I V +D +Y N++G A +A L+V +E E
Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE 5357
Score = 58.2 bits (139), Expect = 8e-08
Identities = 29/107 (27%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
Query: 712 VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771
+ +P P F+++P++ S+G+ +SC I G+P P V W +D + + F +
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAG-ARFRLA 59
Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 818
Q+ D++ L + + +GQY +N +GE V L + +A A
Sbjct: 60 QDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACA 106
Score = 57.0 bits (136), Expect = 2e-07
Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK-NGMQVLE 219
P F +L V GQ +C+++ +P Q TW K PL+ S+RV +S Q+L
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
I V +D+GVYTC V N G + + L
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551
Score = 55.8 bits (133), Expect = 4e-07
Identities = 44/150 (29%), Positives = 61/150 (40%), Gaps = 9/150 (6%)
Query: 1699 NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP 1758
N + A +++ + S + S G+ T+ L A E + AE P P
Sbjct: 188 NPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMR-------AEGAPASPP 240
Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
S R V EG AR C + G P PE VW KD Q + E R + D N L I
Sbjct: 241 --STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKI 298
Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
D YTC A N +G+ + ++V
Sbjct: 299 LFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 53.9 bits (128), Expect = 1e-06
Identities = 80/295 (27%), Positives = 113/295 (38%), Gaps = 57/295 (19%)
Query: 1067 LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPP 1126
LK + D R + R E + F + L D+ E L LQC+VS DP
Sbjct: 2616 LKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS-DPE 2674
Query: 1127 ATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQV 1185
A ++W +G L + K+ L G+ V + PED GLY C G E +V
Sbjct: 2675 AHVVWRKDGVQLGPSDKYDFLHTAGTRGLV-VHDVSPEDAGLYTC----HVGSEETRARV 2729
Query: 1186 TVDDAPASENTKAPEMKSRRPKS-SLPPVLGTESDA------------------------ 1220
V D + M+ +S S VL ES +
Sbjct: 2730 RVHDLHVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQG 2789
Query: 1221 ----TVKKKPAPK-----------TPPKAAM-----PPQIIQFPEDQKVRAGESVELFGK 1260
V ++ AP KA++ P II+ EDQ V GE VEL +
Sbjct: 2790 RKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCE 2849
Query: 1261 VT--GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVE 1313
++ GT P+ W+K RK I++S+ V + L I A + G YT VE
Sbjct: 2850 LSRAGT-PV--HWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901
Score = 53.1 bits (126), Expect = 2e-06
Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 1/113 (0%)
Query: 603 KKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
+K + + L S AP FL+ LSD V+ G VT+ QVS P + W +G
Sbjct: 7443 RKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAP 7502
Query: 663 IQESEDFHFEQRGTQHS-LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714
++ S L I V ED G YTC N+ G V T VL E
Sbjct: 7503 LESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAE 7555
Score = 53.1 bits (126), Expect = 2e-06
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 4/98 (4%)
Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----L 568
AP+F L D V+ GQ L C V P + TW +G P++ + + + L
Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 7521
Query: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS 606
I + ED G YTC NALG V+ + + E+ SS
Sbjct: 7522 TILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSS 7559
Score = 52.4 bits (124), Expect = 4e-06
Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
Query: 1748 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
A AE+ PH F + V EGS A F C++ G P P V W KD + + E ++
Sbjct: 104 ACAEQAPH----FLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVR 159
Query: 1808 YDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1850
+E G S L I D Y +A N LG A+ A L+V++
Sbjct: 160 VEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203
Score = 52.0 bits (123), Expect = 5e-06
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F + V G A C+I G P P+V W KD Q + F++ D D L
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLT 68
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
I D+ D +Y C+A N++GEA L V+
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100
Score = 51.6 bits (122), Expect = 7e-06
Identities = 74/357 (20%), Positives = 127/357 (35%), Gaps = 59/357 (16%)
Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIIL---SQEGSLCSVSIEKALPEDR 1165
V EGK L C V+ +P +W +G+ + + ++ +QE + + K DR
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ--SDR 306
Query: 1166 GLYKCVAKNDAGQAECSCQVTVDD--APASENTKAPEMKSRRPKSSLPPV---------- 1213
GLY C A N GQ S V V + P + + E++ + + L V
Sbjct: 307 GLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWF 366
Query: 1214 ----------------LGTESDATVKKKPA-------------PKTPPKAAMPPQII-QF 1243
GTE TV+ A +T + A+ ++ +
Sbjct: 367 KEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKL 426
Query: 1244 PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQE 1303
P VR G++ +F W++ ++++ + + LTI E
Sbjct: 427 PRKTAVRVGDTA-MFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLE 485
Query: 1304 HCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSLTLSWYGSSY-DG 1359
G + G Q V PP P +++ SS+ LSW + +
Sbjct: 486 DVGQVAFMA----GDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGER 541
Query: 1360 GSAVQSYSIEIWDSANKTW---KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
+ Y +E TW E + V D+ + ++FRV A+N +G S
Sbjct: 542 PVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQS 598
Score = 51.2 bits (121), Expect = 9e-06
Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106
G TA+FE + G P+P VTW+++ + R L T+SLV+ V +D G YTC
Sbjct: 6371 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTR-LSQQQEGTTYSLVLRHVASKDAGVYTC 6429
Query: 107 EATNGSGARQVTVELTVEG 125
A N G EL V G
Sbjct: 6430 LAQNTGGQVLCKAELLVLG 6448
Score = 50.4 bits (119), Expect = 2e-05
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 3/100 (3%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
P+ + ++DV G + + DP ++ W + L + + QEG+ S+ +
Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVL 6416
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE 1194
+D G+Y C+A+N GQ C ++ V D+ P SE
Sbjct: 6417 RHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSE 6456
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/93 (37%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158
F ++L D + EG+ L L C+ S+ D P + WT +GKTL+ + LS EG + I
Sbjct: 3098 FSRELTDATITEGEDLTLVCETSTCDIP--VCWTKDGKTLRGSARCQLSHEGHRAQLLIT 3155
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
A +D G YKC +AG A S V V P
Sbjct: 3156 GATLQDSGRYKC----EAGGACSSSIVRVHARP 3184
Score = 49.7 bits (117), Expect = 3e-05
Identities = 73/332 (21%), Positives = 116/332 (34%), Gaps = 24/332 (7%)
Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS---GKASMSAE 247
+V W KG +QP R V + Q+L I G +D G Y C + GS A+
Sbjct: 4653 EVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLAQGSICPAAATFQVA 4712
Query: 248 LSIQGLDSANRSFVRETKATNSDVR-----KEVTNVISKESKLDSLEAAAKSKNCSS--P 300
LS +D A + + A D+ +S+E LDS+ + S P
Sbjct: 4713 LSPASVDEAPQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDGRSQRLP 4772
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITL--QAARVQPEPRA 358
Q + E D T+ T S +T +A R P A
Sbjct: 4773 QEAEEVAPDLSEGYSTADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAGRPGTSPLA 4832
Query: 359 PGLGV-LSPSGEERKRPAP---PRPATFPTRQPGLGSQDVVSKAANRRIPMEG------Q 408
+G +PS + +++ P RP LG + A + +G
Sbjct: 4833 SKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGDPSMDKAAVKIQAAFKGYKVRKEM 4892
Query: 409 RDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR-RQEGSIEVYEDA 467
+ P F E + ++ C V+ W +G + + I+ D
Sbjct: 4893 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGD- 4951
Query: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQLSCS 499
G+ L + D+G Y+C SN GQ++ S
Sbjct: 4952 GTCSLLITGLDRADAGCYTCQVSNKFGQVTHS 4983
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 16/125 (12%)
Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE-G 1150
+S AP F ++L D V G+ + L CQVS+ P A W+ +G L+++ +++S
Sbjct: 7457 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 7516
Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
+ ++I + ED G+Y C +V +A + T K+ RP SS
Sbjct: 7517 NFQLLTILVVVAEDLGVYTC---------------SVSNALGTVTTTGVLRKAERPSSSP 7561
Query: 1211 PPVLG 1215
P +G
Sbjct: 7562 CPDIG 7566
Score = 49.3 bits (116), Expect = 4e-05
Identities = 40/182 (21%), Positives = 65/182 (35%), Gaps = 26/182 (14%)
Query: 366 PSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEV 425
P G E++ P +P R GL S D P F + + V
Sbjct: 7433 PEGLEKEGPPRKKPGLASFRLSGLKSWDRA------------------PTFLRELSDETV 7474
Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTY 485
Q+V C+VS P + W +G P+ + L +L D G Y
Sbjct: 7475 VLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVY 7534
Query: 486 SCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQ--------DFVLQCSV 537
+C+ SNA G ++ + L+ P V D ++ + +++QCS+
Sbjct: 7535 TCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVTYIVQCSL 7594
Query: 538 RG 539
G
Sbjct: 7595 EG 7596
Score = 48.1 bits (113), Expect = 8e-05
Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F K ++DLEV E +A F C++ P E WFK++ + S + I+ +E L +
Sbjct: 335 FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIE-EEGTERRLTVR 392
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+V DDDA Y C+ + AEL V+
Sbjct: 393 NVSADDDAVYICETPEG---SRTVAELAVQ 419
Score = 47.8 bits (112), Expect = 1e-04
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)
Query: 1751 EEKPH-------VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH 1803
EEKP V P + +V +GS+ F K+EG P P V W +++ E
Sbjct: 5357 EEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---ERGV 5413
Query: 1804 FQIDYDEDGNC--------SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
I D G SL++ DV YTC A N+ G+A C+A L V + + E
Sbjct: 5414 LWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473
Query: 1856 GEGEEEE 1862
+ + +E
Sbjct: 5474 EQEKVKE 5480
Score = 47.8 bits (112), Expect = 1e-04
Identities = 26/87 (29%), Positives = 38/87 (43%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91
AP F+ + + G + +V P Q TW ++G P+ S R L+ ++ L
Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 7521
Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVT 118
I V ED G YTC +N G T
Sbjct: 7522 TILVVVAEDLGVYTCSVSNALGTVTTT 7548
Score = 47.0 bits (110), Expect = 2e-04
Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 5/89 (5%)
Query: 1099 AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158
+F + LQDV E +K+ L+C++S P + W +G L+ K + ++ +G+ S++I
Sbjct: 2167 SFSRPLQDVVTTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225
Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
+ D+G+Y C DA A+ S V V
Sbjct: 2226 RCEFADQGVYVC----DAHDAQSSASVKV 2250
Score = 46.6 bits (109), Expect = 2e-04
Identities = 54/236 (22%), Positives = 86/236 (36%), Gaps = 16/236 (6%)
Query: 1020 SGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKR 1079
+ PL A A ++KP +P ++P ++L S + K V +
Sbjct: 4828 TSPLASKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGDPSMD------KAAVKIQA 4881
Query: 1080 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK 1139
G ++ + +G P F D G L L+C V+S W +G L
Sbjct: 4882 AFKGYKVRKEMKQQEG--PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELT 4939
Query: 1140 TTKFIILSQEG-SLCSVSIEKALPEDRGLYKCVAKNDAGQ-AECSCQVTVDDAPASENTK 1197
+ + Q G CS+ I D G Y C N GQ +C V +E++
Sbjct: 4940 DGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSS 4999
Query: 1198 APEMKS--RRPKSSLPPVLGTESDATVKKK----PAPKTPPKAAMPPQIIQFPEDQ 1247
E+ RR L + T+S A V + A + P + P + ED+
Sbjct: 5000 GGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADWQTYREDE 5055
Score = 46.6 bits (109), Expect = 2e-04
Identities = 53/231 (22%), Positives = 87/231 (37%), Gaps = 46/231 (19%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGSLCSVS 1156
P F+++L D G+ + L C+V+ P I W +GK ++ I++ C++
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
++ D G Y C A + AG ++ V P N K R + P V G
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVN------KVR----ASPFVEGE 6123
Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
++ T + AP PQI + + + G KF+
Sbjct: 6124 DAQFTCTIEGAPY--------PQIRWYKDGALLTTGN-------------------KFQT 6156
Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
+ + V L I AA +E G Y + N+LGS +A L +
Sbjct: 6157 LSEPRSGLLV--------LVIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 44.3 bits (103), Expect = 0.001
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F++ L+D+ V EG L+C +SS A + W L+ L QEG++ + +
Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSS-VAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRN 3245
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
P+D G Y C G S +TV PA
Sbjct: 3246 LRPQDSGRYSC----SFGDQTTSATLTVTALPA 3274
Score = 44.3 bits (103), Expect = 0.001
Identities = 63/266 (23%), Positives = 98/266 (36%), Gaps = 24/266 (9%)
Query: 433 FRCEVS-GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG--TYSCTA 489
F C +S +P E +W++ G V+ + V D H L L A+ +G T++C
Sbjct: 4451 FTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRD 4510
Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
+ A +L+ A + S + L A + L C R +
Sbjct: 4511 AVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGL-CGYR-------VEVK 4562
Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
G Q+ E + P + + A +G A VH ++ R +
Sbjct: 4563 EGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVG-----AGEPVHLPQTVRLA 4617
Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
E PV P +P+AP +V G V++ ++V EVIW IQ F
Sbjct: 4618 EPPKPVPP-QPSAP------ESRQVAAGEDVSLELEVVAEAG-EVIWHKGMERIQPGGRF 4669
Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTC 695
+G Q L I+ ED G Y C
Sbjct: 4670 EVVSQGRQQMLVIKGFTAEDQGEYHC 4695
Score = 43.5 bits (101), Expect = 0.002
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
V P + PP A + V+ + + + +++ + VTWLK L P +
Sbjct: 697 VRAAPGLTANKPPAAAAR--EVLARLHEEAQLLAELSDQAAA-VTWLKDGRTLSPGPKYE 753
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
V G +VL + V +DD G+Y C+ G ++ +LS+QGL
Sbjct: 754 VQASAGRRVLLVRDVARDDAGLYECVSRGG----RIAYQLSVQGL 794
Score = 43.5 bits (101), Expect = 0.002
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 5/138 (3%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGS-LCSV 1155
P F K++ EG+ C + P I W +G L T KF LS+ S L +
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD--APASENTKAPEMKSRRPKSSLPPV 1213
I A ED GLY+C N G A S ++ + A E ++ + ++L
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERA 6227
Query: 1214 LGTESDATVKKKPAPKTP 1231
E + +K+ PK P
Sbjct: 6228 -DQEVTSVLKRLLGPKAP 6244
Score = 43.5 bits (101), Expect = 0.002
Identities = 26/89 (29%), Positives = 35/89 (39%)
Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
P F + + D VV G + C++ P + W KD + S I L
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522
Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1846
I V +D YTC N+LG T T L
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551
Score = 42.7 bits (99), Expect = 0.003
Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 15/159 (9%)
Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
W K G +R R G + TG+ K E+ S + +
Sbjct: 3128 WTKDGKTLRGSARCQLSH--EGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRV----- 3180
Query: 1754 PHVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
H +P F + ++DLEV+EG AA C + P V W + +R + + E
Sbjct: 3181 -HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSL-RQEGA 3237
Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
L++ ++ D +Y+C S G+ T +A L V +
Sbjct: 3238 MLELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTAL 3272
Score = 42.4 bits (98), Expect = 0.004
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F KL++ EG L+C++S P + W +TL+ L Q+G++C + I
Sbjct: 3276 FIGKLRNKEATEGATATLRCELSKAAP--VEWRKGSETLRDGDRYCLRQDGAMCELQIRG 3333
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
D Y CV G+ S +T+ PA
Sbjct: 3334 LAMVDAAEYSCV----CGEERTSASLTIRPMPA 3362
Score = 42.4 bits (98), Expect = 0.004
Identities = 39/155 (25%), Positives = 62/155 (40%), Gaps = 17/155 (10%)
Query: 1049 PMGNAKPDENLKSASKEELKKD-------VKNDVNCKRGHAGTTDNEKRSESQGTAPA-- 1099
P+ K E+L+ + L++D + G E+R+ + T A
Sbjct: 3390 PVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKALP 3449
Query: 1100 --FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
F + L++ EG +L C++S P + W + L+ IL QEG+ C + I
Sbjct: 3450 AKFTEGLRNEEAVEGATAMLWCELSKVAP--VEWRKGPENLRDGDRYILRQEGTRCELQI 3507
Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
D G Y CV GQ S +T+ PA
Sbjct: 3508 CGLAMADAGEYLCV----CGQERTSATLTIRALPA 3538
Score = 41.2 bits (95), Expect = 0.010
Identities = 44/204 (21%), Positives = 71/204 (34%), Gaps = 40/204 (19%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
+EG A F+ V + V W R+G + +F + + SL I + ED G+
Sbjct: 1911 EEGGEATFQCVVSP-SDVAVVWFRDGALLQPSEKFAISQS-GASHSLTISDLVLEDAGQI 1968
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
T EA S + + V E P F
Sbjct: 1969 TVEAEGASSSAALRVR-------------------------------------EAPVLFK 1991
Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
KL V+E ++T RP P++ W + L P V + + L +H V
Sbjct: 1992 KKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVG 2050
Query: 225 QDDVGVYTCLVVNGSGKASMSAEL 248
D G + C + +A ++ E+
Sbjct: 2051 FADRGFFGCETPDDKTQAKLTVEM 2074
Score = 40.4 bits (93), Expect = 0.016
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
P +F L + V EG C ++ P V W GN L+P + S+ ++ M L
Sbjct: 3184 PVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLELV 3242
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
+ + D G Y+C G + SA L++ L + +R +AT
Sbjct: 3243 VRNLRPQDSGRYSC----SFGDQTTSATLTVTALPAQFIGKLRNKEAT 3286
Score = 38.9 bits (89), Expect = 0.047
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 5/78 (6%)
Query: 1111 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKC 1170
E + ++L C P A + W + L ++ +S EG + + I + +P D G+Y+C
Sbjct: 2482 ELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRC 2540
Query: 1171 VAKNDAGQAECSCQVTVD 1188
AG A S +VTV+
Sbjct: 2541 ----QAGSAHSSTEVTVE 2554
Score = 37.4 bits (85), Expect = 0.14
Identities = 46/236 (19%), Positives = 84/236 (35%), Gaps = 49/236 (20%)
Query: 1074 DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL 1133
+ +C+ G + + +E +G + +V G +L C+V+ P + W
Sbjct: 1143 EYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQ-PQTEVTWYK 1201
Query: 1134 NGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS 1193
+GK L ++ + + +G + +++ D G Y C +AG S Q+ +
Sbjct: 1202 DGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSC----EAGGQRVSFQLHI------ 1251
Query: 1194 ENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGE 1253
T PKA + + E + AG
Sbjct: 1252 ------------------------------------TEPKAVFAKEQLVHNE-VRTEAGA 1274
Query: 1254 SVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
S L +V Q TW K K++ S +++E + +L + A Q G YT
Sbjct: 1275 SATLSCEVAQAQ-TEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYT 1329
Score = 37.4 bits (85), Expect = 0.14
Identities = 56/248 (22%), Positives = 89/248 (35%), Gaps = 47/248 (18%)
Query: 20 DPSRVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
D + ++ +T PA FI RN EGATA R V W + + + G R
Sbjct: 3260 DQTTSATLTVTALPAQFIGKLRNKEATEGATATL--RCELSKAAPVEWRKGSETLRDGDR 3317
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ L L I + D +Y+C G + + LT+
Sbjct: 3318 YCLRQD-GAMCELQIRGLAMVDAAEYSCVC----GEERTSASLTI--------------- 3357
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
RP P F +L EG C+++ V W KG
Sbjct: 3358 -------------RPM-----PAHFIGRLRHQESIEGATATLRCELS--KAAPVEWRKGR 3397
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR 258
L+ R S+ + + L+I G+ D G Y+C+ G+ SA L+++ L +
Sbjct: 3398 ESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCV----CGEERTSATLTVKALPAKFT 3453
Query: 259 SFVRETKA 266
+R +A
Sbjct: 3454 EGLRNEEA 3461
Score = 37.4 bits (85), Expect = 0.14
Identities = 37/137 (27%), Positives = 55/137 (40%), Gaps = 21/137 (15%)
Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
K S+PQ G SP A P PP SCK++P P +P L + +
Sbjct: 7038 KQGSAPQEGCSPHPAV--APCPPGSFPPGSCKEAP-LVPSSPFLGQPQA----------- 7083
Query: 355 EPRAPGLGVLSPSGEERKRPA----PPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRD 410
P AP SP + + P P RP P PG SQ S+ ++ R+
Sbjct: 7084 -PPAPAKA--SPPLDSKMGPGDISLPGRPKPGPCSSPGSASQASSSQVSSLRVGSSQVGT 7140
Query: 411 SAFPKFESKPQSQEVKE 427
P +++ +QE ++
Sbjct: 7141 EPGPSLDAEGWTQEAED 7157
Score = 37.0 bits (84), Expect = 0.18
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
+P F + ++ L+ EGS A C++ P VVW K ++ + + + L
Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRL-QGCTAEL 3946
Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCT 1843
++ D+ +D +YTC + AT T
Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLT 3973
Score = 36.6 bits (83), Expect = 0.23
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
+ +RD +E +C++ +V WFK Q ++ +++ D LIISDV
Sbjct: 2294 RPLRDKIAMEKHRGVLECQVSR-ASAQVRWFKGSQELQPGPKYELVSDGLYR-KLIISDV 2351
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIVE 1849
+D+ YTC A G+ +A+ VE
Sbjct: 2352 HAEDEDTYTCDA----GDVKTSAQFFVE 2375
Score = 36.6 bits (83), Expect = 0.23
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F +L+ EG L+C++S P + W ++L+ L Q+G++C + I
Sbjct: 3364 FIGRLRHQESIEGATATLRCELSKAAP--VEWRKGRESLRDGDRHSLRQDGAVCELQICG 3421
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
D G Y CV G+ S +TV PA
Sbjct: 3422 LAVADAGEYSCV----CGEERTSATLTVKALPA 3450
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/80 (28%), Positives = 36/80 (45%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106
G + E V + + W ++G +T G +D GT SL+I + D G YTC
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971
Query: 107 EATNGSGARQVTVELTVEGS 126
+ +N G + + V GS
Sbjct: 4972 QVSNKFGQVTHSACVVVSGS 4991
Score = 35.8 bits (81), Expect = 0.40
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
F L V EG + QC VS A ++W +G L+ ++ +SQ G+ S++I
Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQPSEKFAISQSGASHSLTISD 1959
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
+ ED G A+ A S + V +AP
Sbjct: 1960 LVLEDAGQITVEAEG----ASSSAALRVREAP 1987
Score = 35.4 bits (80), Expect = 0.52
Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 1246 DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS-KLTILAARQEH 1304
D + + G+++ L V + W+K ++ + H ++ +G+ L I +
Sbjct: 4906 DTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRAD 4965
Query: 1305 CGCYTLLVENKLG 1317
GCYT V NK G
Sbjct: 4966 AGCYTCQVSNKFG 4978
Score = 35.4 bits (80), Expect = 0.52
Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 20/125 (16%)
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF--EVLQNEDVFT 778
P F+ + T LGQSV ++C ++ P W +DG L + L+N + T
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522
Query: 779 LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN-SSARALPRGREPAS--CEDLCGGG 835
++ +++ +G +C VS L ++ L + P+S C D+ G
Sbjct: 7523 IL-------------VVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDI--GE 7567
Query: 836 VGADG 840
V ADG
Sbjct: 7568 VYADG 7572
Score = 35.0 bits (79), Expect = 0.68
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 1736 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
ES +D + A L P V + S + + EG A F C + D VVWF+D
Sbjct: 1881 ESRDDHTSAQLTVSV---PRVVKFMSG-LSTVVAEEGGEATFQCVVSP-SDVAVVWFRDG 1935
Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
++ S F I + SL ISD+ +D + T +A + A
Sbjct: 1936 ALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQITVEAEGASSSA 1979
Score = 35.0 bits (79), Expect = 0.68
Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
FK+KL+ V E + L+ +++ P + WT N L K + + EG+ + +
Sbjct: 1990 FKKKLEPQTVEERSSVTLEVELTRPWPE-LRWTRNATALAPGKNVEIHAEGARHRLVLHN 2048
Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQV 1185
DRG + C +D QA+ + ++
Sbjct: 2049 VGFADRGFFGCETPDDKTQAKLTVEM 2074
Score = 35.0 bits (79), Expect = 0.68
Identities = 22/100 (22%), Positives = 39/100 (39%)
Query: 1235 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSK 1294
A PP + ED + + G + + + G + TW K Q+ +S + +
Sbjct: 6354 ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 6413
Query: 1295 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
L + + G YT L +N G + L V+ + P
Sbjct: 6414 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEP 6453
Score = 34.3 bits (77), Expect = 1.2
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 7/105 (6%)
Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
+F +R E +EG+ A C++ E W K +S+R+ + D C L I
Sbjct: 3363 HFIGRLRHQESIEGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQD-GAVCELQI 3419
Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
+ D +Y+C GE +A L V+ + EG EE
Sbjct: 3420 CGLAVADAGEYSCVC----GEERTSATLTVKALPAKFTEGLRNEE 3460
Score = 34.3 bits (77), Expect = 1.2
Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV---VWFKDDQSIRESRHFQI 1806
A+ K K + + ++E +EG A F+C++ PEV W DD+ + S + ++
Sbjct: 4332 AQLKVTAKNTVVRGLENVEALEGGEALFECQLS---QPEVAAHTWLLDDEPVHTSENAEV 4388
Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
+ E+G L++ D +C+ G+ +A L V
Sbjct: 4389 VFFENGLRHLLLLKNLRPQD---SCRVTFLAGDMVTSAFLTV 4427
Score = 34.3 bits (77), Expect = 1.2
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 12/106 (11%)
Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-------KTTKFIILS--Q 1148
P ++ V +G + +V P T+ W T + + S Q
Sbjct: 5371 PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQ 5430
Query: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
+ SL + + + + +G Y C+A N AGQA CS + V P E
Sbjct: 5431 QHSLVLLDVGR---QHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/98 (20%), Positives = 39/98 (39%)
Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
P F A +G ++ + C +A WL+DG L H + +L+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 818
+ + AG Y + N+ G+ + +++ S + A
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEA 4995
Score = 33.1 bits (74), Expect = 2.6
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
A F + L+ V G + L C++S A ++W L+ K + EG + S++
Sbjct: 1808 AAKFCRLLEPVCGELGGTVTLACELSP-ACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLT 1866
Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQV 1185
+ ED G Y C +++D A+ + V
Sbjct: 1867 VLGLRAEDAGEYVCESRDDHTSAQLTVSV 1895
Score = 32.7 bits (73), Expect = 3.4
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVCG 1823
+++ G+ A C++ P EV W+KD + + S ++ E C+ L++ V
Sbjct: 1175 EVQAEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRM---EVKGCTRRLVVQQVGK 1230
Query: 1824 DDDAKYTCKA 1833
D +Y+C+A
Sbjct: 1231 ADAGEYSCEA 1240
Score = 32.7 bits (73), Expect = 3.4
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
+V WH+ + I GGRF + R LVI ED+G+Y C GS
Sbjct: 4653 EVIWHKGMERIQPGGRFEVVSQGRQQM-LVIKGFTAEDQGEYHCGLAQGS 4701
Score = 32.7 bits (73), Expect = 3.4
Identities = 20/62 (32%), Positives = 28/62 (45%)
Query: 1237 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
PP + D GE+V+L +VTGT +W K K +Q H + +GS
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 1297 IL 1298
IL
Sbjct: 6073 IL 6074
Score = 32.3 bits (72), Expect = 4.4
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
K + D V G C++ P V W KD ++IR+S+ + + E L+I
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDV-VCEGTMAMLVIRGA 2888
Query: 1822 CGDDDAKYTCKAVNSLGEATCTAE 1845
D +YTC+ S A+ E
Sbjct: 2889 SLKDAGEYTCEVEASKSTASLHVE 2912
Score = 32.3 bits (72), Expect = 4.4
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
F++ +R+ E VEG+ A C++ E W K +++R+ + I E C L I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCELQIC 3508
Query: 1820 DVCGDDDAKYTCKAVNSLGEATCT 1843
+ D +Y C AT T
Sbjct: 3509 GLAMADAGEYLCVCGQERTSATLT 3532
Score = 32.0 bits (71), Expect = 5.8
Identities = 45/163 (27%), Positives = 61/163 (37%), Gaps = 25/163 (15%)
Query: 654 VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
V WL +G + + + + L +++V +D G Y C + G + Q L+VQ
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECV--SRGGRIAYQ--LSVQ 792
Query: 714 EPHDGTQPWFISKPRS---VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF-E 769
F+ K + V A G C + VHW +DG L GH E
Sbjct: 793 -----GLARFLHKDMAGSCVDAVAGGPAQFECE-TSEAHVHVHWYKDGMEL----GHSGE 842
Query: 770 VLQNEDVFT---LVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
EDV T LV V G Y RVGE S L
Sbjct: 843 RFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRL 881
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
+ D++V EGS+A F C+I V WF D + + +ID G L + +
Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070
Query: 1824 DDDAKYTCKAVNSLGEATC---------TAELIVETMEEGE 1855
D +A + A + EL T+ EGE
Sbjct: 3071 KDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE 3111
Score = 31.2 bits (69), Expect = 9.9
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC--SLIISDVCGDDDAKY 1829
G++A C++ EV W+KD + + S +I E C L++ D +Y
Sbjct: 1273 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRI---EAAGCMRQLVVQQAGQADAGEY 1328
Query: 1830 TCKA 1833
TC+A
Sbjct: 1329 TCEA 1332
Score = 31.2 bits (69), Expect = 9.9
Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVC 1822
R+++ G++A C++ EV W+KD + + S ++ E C+ L++
Sbjct: 1634 REVQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRV---EAVGCTRRLVVQQAG 1689
Query: 1823 GDDDAKYTCKA 1833
D +Y+C+A
Sbjct: 1690 QADAGEYSCEA 1700
>gi|4758194 serine/threonine kinase 17B [Homo sapiens]
Length = 372
Score = 147 bits (370), Expect = 1e-34
Identities = 77/204 (37%), Positives = 131/204 (64%), Gaps = 8/204 (3%)
Query: 1458 QKVSDFYDIEER-LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKE--KENIRQEISIMN 1514
+ ++FY + + LG GKF V + + K T + +A KF K + + I EI+++
Sbjct: 26 ENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLE 85
Query: 1515 CLHH-PKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFEL-TERECIKYMRQISEG 1572
P+++ + +E + I+++LE +GGE+F + E E+ +E + I+ ++QI EG
Sbjct: 86 LAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEG 145
Query: 1573 VEYIHKQGIVHLDLKPENIMC--VNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAP 1630
V Y+H+ IVHLDLKP+NI+ + G IK++DFG++R++ +A L+ + GTPE++AP
Sbjct: 146 VYYLHQNNIVHLDLKPQNILLSSIYPLGD-IKIVDFGMSRKIGHACELREIMGTPEYLAP 204
Query: 1631 EVINYEPIGYATDMWSIGVICYIL 1654
E++NY+PI ATDMW+IG+I Y+L
Sbjct: 205 EILNYDPITTATDMWNIGIIAYML 228
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,012,692
Number of Sequences: 37866
Number of extensions: 4204427
Number of successful extensions: 39123
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 814
Number of HSP's successfully gapped in prelim test: 759
Number of HSP's that attempted gapping in prelim test: 16248
Number of HSP's gapped (non-prelim): 13638
length of query: 1863
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1746
effective length of database: 13,817,196
effective search space: 24124824216
effective search space used: 24124824216
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.