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Search of human proteins with 11559929
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11559929 coatomer protein complex, subunit gamma 1 [Homo
sapiens]
(874 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11559929 coatomer protein complex, subunit gamma 1 [Homo sapi... 1723 0.0
gi|109134349 coatomer protein complex, subunit gamma 2 [Homo sap... 1422 0.0
gi|22027651 adaptor-related protein complex 1 beta 1 subunit iso... 68 4e-11
gi|22027653 adaptor-related protein complex 1 beta 1 subunit iso... 68 4e-11
gi|71773106 adaptor-related protein complex 2, beta 1 subunit is... 62 2e-09
gi|4557469 adaptor-related protein complex 2, beta 1 subunit iso... 62 2e-09
gi|166197671 adaptor-related protein complex 4, beta 1 subunit [... 57 1e-07
gi|71773010 adaptor-related protein complex 1, gamma 1 subunit i... 52 2e-06
gi|71772942 adaptor-related protein complex 1, gamma 1 subunit i... 52 2e-06
gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [H... 48 3e-05
gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit... 42 0.002
gi|115298659 spectrin, alpha, erythrocytic 1 [Homo sapiens] 37 0.080
gi|221316632 coatomer protein complex, subunit beta 1 [Homo sapi... 36 0.14
gi|221316630 coatomer protein complex, subunit beta 1 [Homo sapi... 36 0.14
gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens] 36 0.14
gi|7662230 ring finger protein 40 [Homo sapiens] 35 0.23
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 35 0.30
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] 35 0.30
gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens] 35 0.30
gi|33636719 translocase of inner mitochondrial membrane 44 [Homo... 34 0.52
gi|118402596 cell division cycle protein 23 [Homo sapiens] 32 2.0
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 32 3.4
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 32 3.4
gi|222418587 hypothetical protein LOC57495 [Homo sapiens] 31 4.4
gi|12025663 ubiquitin-conjugating enzyme E2 variant 1 isoform c ... 31 5.7
gi|40806164 ubiquitin-conjugating enzyme E2 variant 1 isoform a ... 31 5.7
gi|40806190 TMEM189-UBE2V1 readthrough transcript [Homo sapiens] 31 5.7
gi|130484567 HFM1 protein [Homo sapiens] 31 5.7
gi|73765546 ubiquitin-conjugating enzyme E2 variant 1 isoform d ... 31 5.7
gi|40806167 ubiquitin-conjugating enzyme E2 variant 1 isoform a ... 31 5.7
>gi|11559929 coatomer protein complex, subunit gamma 1 [Homo
sapiens]
Length = 874
Score = 1723 bits (4463), Expect = 0.0
Identities = 874/874 (100%), Positives = 874/874 (100%)
Query: 1 MLKKFDKKDEESGGGSNPFQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEH 60
MLKKFDKKDEESGGGSNPFQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEH
Sbjct: 1 MLKKFDKKDEESGGGSNPFQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEH 60
Query: 61 LGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNY 120
LGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNY
Sbjct: 61 LGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNY 120
Query: 121 RGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNE 180
RGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNE
Sbjct: 121 RGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNE 180
Query: 181 AQEAASSDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHGLKSPFAYCMMIRVASKQL 240
AQEAASSDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHGLKSPFAYCMMIRVASKQL
Sbjct: 181 AQEAASSDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHGLKSPFAYCMMIRVASKQL 240
Query: 241 EEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPK 300
EEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPK
Sbjct: 241 EEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPK 300
Query: 301 AALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRL 360
AALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRL
Sbjct: 301 AALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRL 360
Query: 361 MKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDC 420
MKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDC
Sbjct: 361 MKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDC 420
Query: 421 IISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTTNPSKYIRFIYNRV 480
IISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTTNPSKYIRFIYNRV
Sbjct: 421 IISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTTNPSKYIRFIYNRV 480
Query: 481 VLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQK 540
VLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQK
Sbjct: 481 VLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQK 540
Query: 541 ALNAGYILNGLTVSIPGLERALQQYTLEPSEKPFDLKSVPLATAPMAEQRTESTPITAVK 600
ALNAGYILNGLTVSIPGLERALQQYTLEPSEKPFDLKSVPLATAPMAEQRTESTPITAVK
Sbjct: 541 ALNAGYILNGLTVSIPGLERALQQYTLEPSEKPFDLKSVPLATAPMAEQRTESTPITAVK 600
Query: 601 QPEKVAATRQEIFQEQLAAVPEFRGLGPLFKSSPEPVALTESETEYVIRCTKHTFTNHMV 660
QPEKVAATRQEIFQEQLAAVPEFRGLGPLFKSSPEPVALTESETEYVIRCTKHTFTNHMV
Sbjct: 601 QPEKVAATRQEIFQEQLAAVPEFRGLGPLFKSSPEPVALTESETEYVIRCTKHTFTNHMV 660
Query: 661 FQFDCTNTLNDQTLENVTVQMEPTEAYEVLCYVPARSLPYNQPGTCYTLVALPKEDPTAV 720
FQFDCTNTLNDQTLENVTVQMEPTEAYEVLCYVPARSLPYNQPGTCYTLVALPKEDPTAV
Sbjct: 661 FQFDCTNTLNDQTLENVTVQMEPTEAYEVLCYVPARSLPYNQPGTCYTLVALPKEDPTAV 720
Query: 721 ACTFSCMMKFTVKDCDPTTGETDDEGYEDEYVLEDLEVTVADHIQKVMKLNFEAAWDEVG 780
ACTFSCMMKFTVKDCDPTTGETDDEGYEDEYVLEDLEVTVADHIQKVMKLNFEAAWDEVG
Sbjct: 721 ACTFSCMMKFTVKDCDPTTGETDDEGYEDEYVLEDLEVTVADHIQKVMKLNFEAAWDEVG 780
Query: 781 DEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAGVFRGGHDI 840
DEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAGVFRGGHDI
Sbjct: 781 DEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAGVFRGGHDI 840
Query: 841 LVRSRLLLLDTVTMQVTARSLEELPVDIILASVG 874
LVRSRLLLLDTVTMQVTARSLEELPVDIILASVG
Sbjct: 841 LVRSRLLLLDTVTMQVTARSLEELPVDIILASVG 874
>gi|109134349 coatomer protein complex, subunit gamma 2 [Homo
sapiens]
Length = 871
Score = 1422 bits (3680), Expect = 0.0
Identities = 704/874 (80%), Positives = 793/874 (90%), Gaps = 3/874 (0%)
Query: 1 MLKKFDKKDEESGGGSNPFQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEH 60
M+KKFDKKDEESG GSNPFQHLEKSAVLQEAR+FNETPINPR+C HILTKILYL+NQGEH
Sbjct: 1 MIKKFDKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEH 60
Query: 61 LGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNY 120
GTTEATEAFFAMT+LFQSND TLRRMCYLTIKEM+ I+EDVIIVTSSLTKDMTGKED Y
Sbjct: 61 FGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVY 120
Query: 121 RGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNE 180
RGPA+RALC+ITD TMLQAIERYMKQAIVDKV SVSSSALVSSLH++K S+DVVKRW+NE
Sbjct: 121 RGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINE 180
Query: 181 AQEAASSDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHGLKSPFAYCMMIRVASKQL 240
AQEAASSDNIMVQYHALG+LYH+RKNDRLAV+KM++K T+ GLKS FAYCM+IR+AS+ L
Sbjct: 181 AQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLL 240
Query: 241 EEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPK 300
+E + +SPLFDFIESCLRNKHEMV+YEAASAI++LP C+A+ELAPAVSVLQLFCSSPK
Sbjct: 241 KETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPK 300
Query: 301 AALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRL 360
ALRYAAVRTLNKVAMKHPSAVTACNLDLENL+TDSNRSIATLAITTLLKTGSESS+DRL
Sbjct: 301 PALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRL 360
Query: 361 MKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDC 420
MKQISSF+SEISDEFKVVVVQAISALCQKYPRKH+V+M FL MLR++GGFEYKRAIVDC
Sbjct: 361 MKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRDDGGFEYKRAIVDC 420
Query: 421 IISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTTNPSKYIRFIYNRV 480
IISI+EEN ESKE GL+HLCEFIEDCE TVLAT+ILHLLG+EGP+T PSKYIRFI+NRV
Sbjct: 421 IISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRV 480
Query: 481 VLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQK 540
VLE+E VRA AVSALAKFGAQNE +LPSILVLL+RC+MD D+EVRDRATFYLNVL+Q+Q
Sbjct: 481 VLENEAVRAAAVSALAKFGAQNESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQM 540
Query: 541 ALNAGYILNGLTVSIPGLERALQQYTLEPSEKPFDLKSVPLATAPMAEQRTESTPITAVK 600
ALNA YI NGLTVS+PG+E+AL QYTLEPSEKPFD+KS+PLA AP+ EQ+ E T +
Sbjct: 541 ALNATYIFNGLTVSVPGMEKALHQYTLEPSEKPFDMKSIPLAMAPVFEQKAEITLVAT-- 598
Query: 601 QPEKVAATRQEIFQEQLAAVPEFRGLGPLFKSSPEPVALTESETEYVIRCTKHTFTNHMV 660
+PEK+A +RQ+IFQEQLAA+PEF +GPLFKSS EPV LTE+ETEY +RC KH FTNH+V
Sbjct: 599 KPEKLAPSRQDIFQEQLAAIPEFLNIGPLFKSS-EPVQLTEAETEYFVRCIKHMFTNHIV 657
Query: 661 FQFDCTNTLNDQTLENVTVQMEPTEAYEVLCYVPARSLPYNQPGTCYTLVALPKEDPTAV 720
FQFDCTNTLNDQ LE VTVQMEP+++YEVL +PA SLPYNQPG CYTLV LP +DPTAV
Sbjct: 658 FQFDCTNTLNDQLLEKVTVQMEPSDSYEVLSCIPAPSLPYNQPGICYTLVRLPDDDPTAV 717
Query: 721 ACTFSCMMKFTVKDCDPTTGETDDEGYEDEYVLEDLEVTVADHIQKVMKLNFEAAWDEVG 780
A +FSC MKFTV+DCDP TG D++GY+DEYVLEDLEVTV+DHIQKV+K NF AAW+EVG
Sbjct: 718 AGSFSCTMKFTVRDCDPNTGVPDEDGYDDEYVLEDLEVTVSDHIQKVLKPNFAAAWEEVG 777
Query: 781 DEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAGVFRGGHDI 840
D FEKEETF LS+ KTLEEAV NI+ FLGM PCERSDKVP+NKN+H+L LAG+FRGG+D+
Sbjct: 778 DTFEKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAGIFRGGYDL 837
Query: 841 LVRSRLLLLDTVTMQVTARSLEELPVDIILASVG 874
LVRSRL L D VTMQVT RS E PVD+ILASVG
Sbjct: 838 LVRSRLALADGVTMQVTVRSKERTPVDVILASVG 871
>gi|22027651 adaptor-related protein complex 1 beta 1 subunit
isoform a [Homo sapiens]
Length = 949
Score = 67.8 bits (164), Expect = 4e-11
Identities = 104/605 (17%), Positives = 242/605 (40%), Gaps = 75/605 (12%)
Query: 65 EATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDV-IIVTSSLTKDMTGKEDNYRGP 123
+ + F + Q+++ L+++ YL + + D+ I+ ++ KD R
Sbjct: 46 DVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRAL 105
Query: 124 AVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALV--SSLHLLKCSFDVVKRWVNEA 181
AVR + I + + + +++ + D+ P V +A V + LH + + +++
Sbjct: 106 AVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTL 165
Query: 182 QEAASSDNIMVQYHALGLLYHVRKN---------DRLAVNKMISKVTRHGLKSPFAYCMM 232
++ S N MV +A+ L + ++ + ++NK+++ + + + +
Sbjct: 166 KDLISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNEC---TEWGQIFI 222
Query: 233 IRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLP----------GCSA 282
+ + + ++D S + + + L + + VV A ++ G
Sbjct: 223 LDCLANYMPKDDREAQS-ICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLL 281
Query: 283 KELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIAT 342
K+LAP + L S + L+Y A+R +N + K P + + + + + +
Sbjct: 282 KKLAPPLVTLL----SAEPELQYVALRNINLIVQKRPE-ILKHEMKVFFVKYNDPIYVKL 336
Query: 343 LAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLF 402
+ +++ S+++I +++ ++ + +E+ +F V+AI K + ++ L
Sbjct: 337 EKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLL 396
Query: 403 TMLREEGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQE 462
+++ + + + AIV I I + E+ ++ LCE ++ + ++ ++G+
Sbjct: 397 DLIQTKVNYVVQEAIV-VIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEY 455
Query: 463 GPKTTNPSKYIRFIYNRVVLEHEEVRAGAVSALAKF----GAQNEEMLPSILVLLKRCVM 518
+ N + + E +V+ ++A+ K + +E++ +L L
Sbjct: 456 AERIDNADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSL---ATQ 512
Query: 519 DDDN-EVRDRATFYLNVLEQKQKALNAGYILNGLTVSIPGLERALQQYTLEPSEKPFDLK 577
D DN ++RDR Y +L S P K
Sbjct: 513 DSDNPDLRDRGYIYWRLL----------------------------------STDPVAAK 538
Query: 578 SVPLATAPMAEQRTESTPITAVKQPEKVAATRQEIFQEQLAAVPEFRGLGPLFKSSPEPV 637
V LA P+ + T+ T + + T ++ + +A E G G + KS P
Sbjct: 539 EVVLAEKPLISEETDLIEPTLLDELICYIGTLASVYHKPPSAFVE-GGRGVVHKSLPPRT 597
Query: 638 ALTES 642
A +ES
Sbjct: 598 ASSES 602
>gi|22027653 adaptor-related protein complex 1 beta 1 subunit
isoform b [Homo sapiens]
Length = 942
Score = 67.8 bits (164), Expect = 4e-11
Identities = 104/605 (17%), Positives = 242/605 (40%), Gaps = 75/605 (12%)
Query: 65 EATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDV-IIVTSSLTKDMTGKEDNYRGP 123
+ + F + Q+++ L+++ YL + + D+ I+ ++ KD R
Sbjct: 46 DVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRAL 105
Query: 124 AVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALV--SSLHLLKCSFDVVKRWVNEA 181
AVR + I + + + +++ + D+ P V +A V + LH + + +++
Sbjct: 106 AVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTL 165
Query: 182 QEAASSDNIMVQYHALGLLYHVRKN---------DRLAVNKMISKVTRHGLKSPFAYCMM 232
++ S N MV +A+ L + ++ + ++NK+++ + + + +
Sbjct: 166 KDLISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNEC---TEWGQIFI 222
Query: 233 IRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLP----------GCSA 282
+ + + ++D S + + + L + + VV A ++ G
Sbjct: 223 LDCLANYMPKDDREAQS-ICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLL 281
Query: 283 KELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIAT 342
K+LAP + L S + L+Y A+R +N + K P + + + + + +
Sbjct: 282 KKLAPPLVTLL----SAEPELQYVALRNINLIVQKRPE-ILKHEMKVFFVKYNDPIYVKL 336
Query: 343 LAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLF 402
+ +++ S+++I +++ ++ + +E+ +F V+AI K + ++ L
Sbjct: 337 EKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLL 396
Query: 403 TMLREEGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQE 462
+++ + + + AIV I I + E+ ++ LCE ++ + ++ ++G+
Sbjct: 397 DLIQTKVNYVVQEAIV-VIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEY 455
Query: 463 GPKTTNPSKYIRFIYNRVVLEHEEVRAGAVSALAKF----GAQNEEMLPSILVLLKRCVM 518
+ N + + E +V+ ++A+ K + +E++ +L L
Sbjct: 456 AERIDNADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSL---ATQ 512
Query: 519 DDDN-EVRDRATFYLNVLEQKQKALNAGYILNGLTVSIPGLERALQQYTLEPSEKPFDLK 577
D DN ++RDR Y +L S P K
Sbjct: 513 DSDNPDLRDRGYIYWRLL----------------------------------STDPVAAK 538
Query: 578 SVPLATAPMAEQRTESTPITAVKQPEKVAATRQEIFQEQLAAVPEFRGLGPLFKSSPEPV 637
V LA P+ + T+ T + + T ++ + +A E G G + KS P
Sbjct: 539 EVVLAEKPLISEETDLIEPTLLDELICYIGTLASVYHKPPSAFVE-GGRGVVHKSLPPRT 597
Query: 638 ALTES 642
A +ES
Sbjct: 598 ASSES 602
>gi|71773106 adaptor-related protein complex 2, beta 1 subunit
isoform a [Homo sapiens]
Length = 951
Score = 62.4 bits (150), Expect = 2e-09
Identities = 90/500 (18%), Positives = 212/500 (42%), Gaps = 44/500 (8%)
Query: 65 EATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDV-IIVTSSLTKDMTGKEDNYRGP 123
+ + F + Q+++ L+++ YL + + D+ I+ +S KD R
Sbjct: 46 DVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRAL 105
Query: 124 AVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSA--LVSSLHLLKCSFDVVKRWVNEA 181
AVR + I + + + +++ + D+ P V +A V+ LH + + +++
Sbjct: 106 AVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSL 165
Query: 182 QEAASSDNIMVQYHALGLLYHVRK---NDRLA------VNKMISKVTRHGLKSPFAYCMM 232
++ + N MV +A+ L + + N L +NK+++ + + + +
Sbjct: 166 RDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNE---CTEWGQIFI 222
Query: 233 IRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVN----LPGCS------A 282
+ S ++D S + + + L + + VV A ++ LP S
Sbjct: 223 LDCLSNYNPKDDREAQS-ICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLL 281
Query: 283 KELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIAT 342
K+LAP + L S + ++Y A+R +N + K P + +++ N I
Sbjct: 282 KKLAPPLVTL----LSGEPEVQYVALRNINLIVQKRPEIL---KQEIKVFFVKYNDPIYV 334
Query: 343 L--AITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNF 400
+ +++ S+++I +++ ++ + +E+ +F V+AI K + ++
Sbjct: 335 KLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVST 394
Query: 401 LFTMLREEGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLG 460
L +++ + + + AIV I I + E+ ++ LCE ++ + ++ ++G
Sbjct: 395 LLDLIQTKVNYVVQEAIV-VIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVG 453
Query: 461 QEGPKTTNPSKYIRFIYNRVVLEHEEVRAGAVSALAKF----GAQNEEMLPSILVLLKRC 516
+ + N + + E +V+ ++A+ K ++ +E++ +L L
Sbjct: 454 EYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSL---A 510
Query: 517 VMDDDN-EVRDRATFYLNVL 535
D DN ++RDR Y +L
Sbjct: 511 TQDSDNPDLRDRGYIYWRLL 530
>gi|4557469 adaptor-related protein complex 2, beta 1 subunit
isoform b [Homo sapiens]
Length = 937
Score = 62.4 bits (150), Expect = 2e-09
Identities = 90/500 (18%), Positives = 212/500 (42%), Gaps = 44/500 (8%)
Query: 65 EATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDV-IIVTSSLTKDMTGKEDNYRGP 123
+ + F + Q+++ L+++ YL + + D+ I+ +S KD R
Sbjct: 46 DVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRAL 105
Query: 124 AVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSA--LVSSLHLLKCSFDVVKRWVNEA 181
AVR + I + + + +++ + D+ P V +A V+ LH + + +++
Sbjct: 106 AVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSL 165
Query: 182 QEAASSDNIMVQYHALGLLYHVRK---NDRLA------VNKMISKVTRHGLKSPFAYCMM 232
++ + N MV +A+ L + + N L +NK+++ + + + +
Sbjct: 166 RDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNE---CTEWGQIFI 222
Query: 233 IRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVN----LPGCS------A 282
+ S ++D S + + + L + + VV A ++ LP S
Sbjct: 223 LDCLSNYNPKDDREAQS-ICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLL 281
Query: 283 KELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIAT 342
K+LAP + L S + ++Y A+R +N + K P + +++ N I
Sbjct: 282 KKLAPPLVTL----LSGEPEVQYVALRNINLIVQKRPEIL---KQEIKVFFVKYNDPIYV 334
Query: 343 L--AITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNF 400
+ +++ S+++I +++ ++ + +E+ +F V+AI K + ++
Sbjct: 335 KLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVST 394
Query: 401 LFTMLREEGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLG 460
L +++ + + + AIV I I + E+ ++ LCE ++ + ++ ++G
Sbjct: 395 LLDLIQTKVNYVVQEAIV-VIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVG 453
Query: 461 QEGPKTTNPSKYIRFIYNRVVLEHEEVRAGAVSALAKF----GAQNEEMLPSILVLLKRC 516
+ + N + + E +V+ ++A+ K ++ +E++ +L L
Sbjct: 454 EYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSL---A 510
Query: 517 VMDDDN-EVRDRATFYLNVL 535
D DN ++RDR Y +L
Sbjct: 511 TQDSDNPDLRDRGYIYWRLL 530
>gi|166197671 adaptor-related protein complex 4, beta 1 subunit
[Homo sapiens]
Length = 739
Score = 56.6 bits (135), Expect = 1e-07
Identities = 98/516 (18%), Positives = 211/516 (40%), Gaps = 50/516 (9%)
Query: 46 HILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDV-II 104
+++ +++ + QG + + F M K + D +++ YL + + + D+ ++
Sbjct: 31 NVIQRVIRYMTQG-----LDMSGVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALL 85
Query: 105 VTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALV--S 162
++L KD + RG A+R++C + + + I++ + + DK V A++ +
Sbjct: 86 AINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQPILNGLRDKASYVRRVAVLGCA 145
Query: 163 SLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLLYHVRKND-RLAVNKMI------ 215
+H L +V VNE + +V + L L + K + + +NK I
Sbjct: 146 KMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQEGGVVINKPIAHHLLN 205
Query: 216 --SKVTRHGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFD---FIESCLRNKHEMVVYEA 270
SK+ + G + + + S EEE LFD ++S L++ VV A
Sbjct: 206 RMSKLDQWGQAEVLNFLLRYQPRS---EEE-------LFDILNLLDSFLKSSSPGVVMGA 255
Query: 271 ASAIVNL----PGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACN 326
+ L P L L CSS L + A+ + ++ P ++
Sbjct: 256 TKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHY 315
Query: 327 LDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISAL 386
++ + I + L + ++ ++ ++++++ + +++S +F + AI +
Sbjct: 316 KKFFCSYSEPH-YIKLQKVEVLCELVNDENVQQVLEELRGYCTDVSADFAQAAIFAIGGI 374
Query: 387 CQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDC 446
+ Y + ++ L + +E +V ++ + E +C+ + C
Sbjct: 375 ARTYTDQCVQILTELLGLRQE----HITTVVVQTFRDLVWLCPQCTEA----VCQALPGC 426
Query: 447 EFTVLATR----ILHLLGQEGPKTTN-PSKYIRFIYNRVVLEHEEVRAGAVSALAK-FGA 500
E + + ++ LLG G + N P F+ N V+ ++AL + F +
Sbjct: 427 EENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTALLRLFLS 486
Query: 501 QNEEMLPSILVLLKRCVMDD-DNEVRDRATFYLNVL 535
+ E + LL C+ ++ D VRDR FY +L
Sbjct: 487 RPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLL 522
>gi|71773010 adaptor-related protein complex 1, gamma 1 subunit
isoform a [Homo sapiens]
Length = 825
Score = 52.4 bits (124), Expect = 2e-06
Identities = 78/413 (18%), Positives = 166/413 (40%), Gaps = 41/413 (9%)
Query: 40 NPRKCAHILTKILYLINQG--EHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSC 97
N +C ++ K+LY+ G H G E KL S T +R+ YL +
Sbjct: 43 NTYRCRNV-AKLLYMHMLGYPAHFGQLECL-------KLIASQKFTDKRIGYLGAMLLLD 94
Query: 98 IAEDV-IIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVS 156
+DV +++T+ + D+ +G A+ L + S M + + +++ + +
Sbjct: 95 ERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLR 154
Query: 157 SSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLLY-----------HVRK 205
A + ++H+++ ++++ ++ + + N V + ++ LL H RK
Sbjct: 155 KKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK 214
Query: 206 NDRLAV-------NKMISKVTRH----GLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDF 254
N++L N ++S + G+ PF ++R+ + L D + D
Sbjct: 215 NEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDI 273
Query: 255 IESCLRNKH------EMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAV 308
+ N ++YE I+++ S + A+++L F + +RY A+
Sbjct: 274 LAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVL-AINILGRFLLNNDKNIRYVAL 332
Query: 309 RTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFM 368
+L K +AV + + + D + SI A+ + ++I +MK++ F+
Sbjct: 333 TSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFL 392
Query: 369 SEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDCI 421
EFK I +KY ++ + +L G + A+ + I
Sbjct: 393 DSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLI 445
>gi|71772942 adaptor-related protein complex 1, gamma 1 subunit
isoform b [Homo sapiens]
Length = 822
Score = 52.0 bits (123), Expect = 2e-06
Identities = 77/410 (18%), Positives = 165/410 (40%), Gaps = 38/410 (9%)
Query: 40 NPRKCAHILTKILYLINQG--EHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSC 97
N +C ++ K+LY+ G H G E KL S T +R+ YL +
Sbjct: 43 NTYRCRNV-AKLLYMHMLGYPAHFGQLECL-------KLIASQKFTDKRIGYLGAMLLLD 94
Query: 98 IAEDV-IIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVS 156
+DV +++T+ + D+ +G A+ L + S M + + +++ + +
Sbjct: 95 ERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLR 154
Query: 157 SSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLLYHV--RKNDRLA-VNK 213
A + ++H+++ ++++ ++ + + N V + ++ LL + R D LA K
Sbjct: 155 KKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK 214
Query: 214 MISKVTR----------------HGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIES 257
++ ++ R G+ PF ++R+ + L D + D +
Sbjct: 215 LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDILAQ 273
Query: 258 CLRNKH------EMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTL 311
N ++YE I+++ S + A+++L F + +RY A+ +L
Sbjct: 274 VATNTETSKNVGNAILYETVLTIMDIKSESGLRVL-AINILGRFLLNNDKNIRYVALTSL 332
Query: 312 NKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEI 371
K +AV + + + D + SI A+ + ++I +MK++ F+
Sbjct: 333 LKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSC 392
Query: 372 SDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDCI 421
EFK I +KY ++ + +L G + A+ + I
Sbjct: 393 EPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLI 442
>gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [Homo
sapiens]
Length = 785
Score = 48.1 bits (113), Expect = 3e-05
Identities = 69/397 (17%), Positives = 161/397 (40%), Gaps = 50/397 (12%)
Query: 36 ETPINPRKCAHI---------------LTKILY--LINQGEHLGTTEATEAFFAMTKLFQ 78
E + ++CAHI L K+LY ++ H G E KL
Sbjct: 24 EREVIQKECAHIRASFRDGDPVHRHRQLAKLLYVHMLGYPAHFGQMECL-------KLIA 76
Query: 79 SNDPTLRRMCYLTIKEMSCIAEDV-IIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTML 137
S+ T +R+ YL + D +++T+S+ D++ +G A+ L + + M
Sbjct: 77 SSRFTDKRVGYLGAMLLLDERHDAHLLITNSIKNDLSQGIQPVQGLALCTLSTMGSAEMC 136
Query: 138 QAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHAL 197
+ + +++ ++ P V A+++++H+++ ++ ++ + + + +
Sbjct: 137 RDLAPEVEKLLLQPSPYVRKKAILTAVHMIRKVPELSSVFLPPCAQLLHERHHGILLGTI 196
Query: 198 GL-----------LYHVRKNDRLAVNKMISKVTR--------HGLKSPFAYCM---MIRV 235
L L H RK V+ + + VT G+ PF ++R+
Sbjct: 197 TLITELCERSPAALRHFRKVVPQLVHILRTLVTMGYSTEHSISGVSDPFLQVQILRLLRI 256
Query: 236 ASKQLEEEDGSRDSPLFDFIESC--LRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQ 293
+ EE + + L + RN V++E I+++ + + AV++L
Sbjct: 257 LGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFETVLTIMDIRSAAGLRVL-AVNILG 315
Query: 294 LFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGS 353
F + +RY A+ +L ++ SAV + + +++ S++ A+ L +
Sbjct: 316 RFLLNSDRNIRYVALTSLLRLVQSDHSAVQRHRPTVVECLRETDASLSRRALELSLALVN 375
Query: 354 ESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKY 390
S++ +M+++ +F+ + + I +++
Sbjct: 376 SSNVRAMMQELQAFLESCPPDLRADCASGILLAAERF 412
>gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit
[Homo sapiens]
Length = 1137
Score = 42.0 bits (97), Expect = 0.002
Identities = 67/412 (16%), Positives = 169/412 (41%), Gaps = 30/412 (7%)
Query: 20 QHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQS 79
+H E+ + QE T P ++ + + + E LG +A+ + KL Q
Sbjct: 49 KHEEEKLIQQELSSLKATVSAPTTTLKMMKECMVRLIYCEMLGY-DASFGYIHAIKLAQQ 107
Query: 80 NDPTLRRMCYLTIKEMSCIAEDVIIV-TSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQ 138
+ +R+ YL + + +++++ +++ KD+ A+ + QI M+
Sbjct: 108 GNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMALTVVSQIFPCEMIP 167
Query: 139 AIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALG 198
A+ ++ + V A+++ + + V+ + ++A ++ V +L
Sbjct: 168 AVLPLIEDKLQHSKEIVRRKAVLALYKFHLIAPNQVQHIHIKFRKALCDRDVGVMAASLH 227
Query: 199 LLYHVRKND----------------RLAVNKMISKVTRHGLKSPFAYCMMIRVASKQLEE 242
+ + K + ++ K+ + H + +P+ ++R+ L +
Sbjct: 228 IYLRMIKENSSGYKDLTGSFVTILKQVVGGKLPVEFNYHSVPAPWLQIQLLRILGL-LGK 286
Query: 243 EDGSRDSPLFDFIESCLR------NKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFC 296
+D ++D ++ LR N +++E + ++ S + L A + F
Sbjct: 287 DDQRTSELMYDVLDESLRRAELNHNVTYAILFECVHTVYSIYPKS-ELLEKAAKCIGKFV 345
Query: 297 SSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESS 356
SPK L+Y ++ L V + P+ + + + + I + L + + +
Sbjct: 346 LSPKINLKYLGLKALTYVIQQDPTLALQHQMTIIECLDHPDPIIKRETLELLYRITNAQN 405
Query: 357 IDRLMKQISSFMSEISDEFKVV-VVQAISALCQKYPRKHA---VLMNFLFTM 404
I +++++ ++ + +E+ +V +V I+ L +KY +A MN +F++
Sbjct: 406 ITVIVQKMLEYLHQSKEEYVIVNLVGKIAELAEKYAPDNAWFIQTMNAVFSV 457
>gi|115298659 spectrin, alpha, erythrocytic 1 [Homo sapiens]
Length = 2419
Score = 37.0 bits (84), Expect = 0.080
Identities = 41/181 (22%), Positives = 71/181 (39%), Gaps = 15/181 (8%)
Query: 367 FMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDCIISIIE 426
F ++ DE + + I Q Y R + N L R EG + ++ + E
Sbjct: 1718 FFQDLDDEESWIEEKLIRVSSQDYGRDLQGVQNLLKKHKRLEGELVAHEPAIQNVLDMAE 1777
Query: 427 ENSESKETGLS----HLCEFIEDCEFTVLATRILHLLGQEGPKTTNPSKYIRFIYNRVVL 482
+ + G L +F+E E ++ L G K +Y++F+ N
Sbjct: 1778 KLKDKAAVGQEEIQLRLAQFVEHWE------KLKELAKARGLKLEESLEYLQFMQN---A 1828
Query: 483 EHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKAL 542
E EE +ALA G + + + +L+K +++D V + T NV Q + L
Sbjct: 1829 EEEEAWINEKNALAVRGDCGDTLAATQSLLMKHEALENDFAVHE--TRVQNVCAQGEDIL 1886
Query: 543 N 543
N
Sbjct: 1887 N 1887
>gi|221316632 coatomer protein complex, subunit beta 1 [Homo
sapiens]
Length = 953
Score = 36.2 bits (82), Expect = 0.14
Identities = 62/331 (18%), Positives = 137/331 (41%), Gaps = 42/331 (12%)
Query: 98 IAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSS 157
+ ++I+V + KD+ + RG +R LC++ ++ +L+ + ++ + + V
Sbjct: 94 LLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRR 153
Query: 158 SALVSSL-------HLLKCSFDVVKRW-VNEAQEAASSDNIMVQYHALGLLYHVRKNDRL 209
+A+++ HL+ + +++ + VNE + + M+ HA DR
Sbjct: 154 NAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHA--------DQDR- 204
Query: 210 AVNKMISKVTRHGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYE 269
A++ + + + + +++ + K R + I + L++ V YE
Sbjct: 205 ALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSER-ARFIRCIYNLLQSSSPAVKYE 263
Query: 270 AASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDL 329
AA +V L A A + L ++ + L ++ +HP A L
Sbjct: 264 AAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIEL-KEHP----AHERVL 318
Query: 330 ENLVTDSNRSIAT-----------LAITTLLKTGSESSIDRLMKQISSFMS----EISDE 374
++LV D R ++T LA+ + E + L K++ + E +D+
Sbjct: 319 QDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDK 378
Query: 375 FKVVVVQAISALCQKYPRKHA----VLMNFL 401
++ ++V+ + + ++P A VLM FL
Sbjct: 379 YRQLLVRTLHSCSVRFPDMAANVIPVLMEFL 409
>gi|221316630 coatomer protein complex, subunit beta 1 [Homo
sapiens]
Length = 953
Score = 36.2 bits (82), Expect = 0.14
Identities = 62/331 (18%), Positives = 137/331 (41%), Gaps = 42/331 (12%)
Query: 98 IAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSS 157
+ ++I+V + KD+ + RG +R LC++ ++ +L+ + ++ + + V
Sbjct: 94 LLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRR 153
Query: 158 SALVSSL-------HLLKCSFDVVKRW-VNEAQEAASSDNIMVQYHALGLLYHVRKNDRL 209
+A+++ HL+ + +++ + VNE + + M+ HA DR
Sbjct: 154 NAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHA--------DQDR- 204
Query: 210 AVNKMISKVTRHGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYE 269
A++ + + + + +++ + K R + I + L++ V YE
Sbjct: 205 ALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSER-ARFIRCIYNLLQSSSPAVKYE 263
Query: 270 AASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDL 329
AA +V L A A + L ++ + L ++ +HP A L
Sbjct: 264 AAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIEL-KEHP----AHERVL 318
Query: 330 ENLVTDSNRSIAT-----------LAITTLLKTGSESSIDRLMKQISSFMS----EISDE 374
++LV D R ++T LA+ + E + L K++ + E +D+
Sbjct: 319 QDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDK 378
Query: 375 FKVVVVQAISALCQKYPRKHA----VLMNFL 401
++ ++V+ + + ++P A VLM FL
Sbjct: 379 YRQLLVRTLHSCSVRFPDMAANVIPVLMEFL 409
>gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens]
Length = 953
Score = 36.2 bits (82), Expect = 0.14
Identities = 62/331 (18%), Positives = 137/331 (41%), Gaps = 42/331 (12%)
Query: 98 IAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSS 157
+ ++I+V + KD+ + RG +R LC++ ++ +L+ + ++ + + V
Sbjct: 94 LLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRR 153
Query: 158 SALVSSL-------HLLKCSFDVVKRW-VNEAQEAASSDNIMVQYHALGLLYHVRKNDRL 209
+A+++ HL+ + +++ + VNE + + M+ HA DR
Sbjct: 154 NAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHA--------DQDR- 204
Query: 210 AVNKMISKVTRHGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYE 269
A++ + + + + +++ + K R + I + L++ V YE
Sbjct: 205 ALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSER-ARFIRCIYNLLQSSSPAVKYE 263
Query: 270 AASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDL 329
AA +V L A A + L ++ + L ++ +HP A L
Sbjct: 264 AAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIEL-KEHP----AHERVL 318
Query: 330 ENLVTDSNRSIAT-----------LAITTLLKTGSESSIDRLMKQISSFMS----EISDE 374
++LV D R ++T LA+ + E + L K++ + E +D+
Sbjct: 319 QDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDK 378
Query: 375 FKVVVVQAISALCQKYPRKHA----VLMNFL 401
++ ++V+ + + ++P A VLM FL
Sbjct: 379 YRQLLVRTLHSCSVRFPDMAANVIPVLMEFL 409
>gi|7662230 ring finger protein 40 [Homo sapiens]
Length = 1001
Score = 35.4 bits (80), Expect = 0.23
Identities = 62/302 (20%), Positives = 125/302 (41%), Gaps = 34/302 (11%)
Query: 405 LREEGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIE---DCE-FTVLATRILHLLG 460
L +G E+ +A V ++ E S+ + + LC+ + D E + A LG
Sbjct: 179 LELQGRMEFSKAAVSRVV----EASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELG 234
Query: 461 QEGPKTTNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMD- 519
+E + + + ++ ++R+ LE+ E++ SA K ++ ++ V D
Sbjct: 235 RENRRLQDLATQLQEKHHRISLEYSELQDKVTSAETK------------VLEMETTVEDL 282
Query: 520 --DDNEVRDRATFYLNVLEQKQKALNAGYILNGLTVSIPGLERALQQYTLEPSEKPFDLK 577
D ++R R L + + LN+GY ++G + G + L E + +
Sbjct: 283 QWDIEKLRKREQKLNKHLAEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELE-E 341
Query: 578 SVPLATAPMAE-QRTESTPITAVKQPEKVAATRQEIFQEQLAAVPEFRGLGPLFK---SS 633
+ LA + MAE ++ ++ AV+ E++ + + +E + E+R L F +
Sbjct: 342 NQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNE 401
Query: 634 PEPVALTESETEYVIRCTKHTFTNHMVFQFDCTNTLNDQTLENVTVQMEPTEA-----YE 688
V E ++ TK++ H + + + L +Q+E T A YE
Sbjct: 402 SLQVKTQLDEARGLLLATKNSHLRH-IEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYE 460
Query: 689 VL 690
+L
Sbjct: 461 ML 462
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 35.0 bits (79), Expect = 0.30
Identities = 133/665 (20%), Positives = 246/665 (36%), Gaps = 104/665 (15%)
Query: 45 AHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVII 104
A+ + K+ YL G + A F + ++ ++ T +R+ YL + DVI+
Sbjct: 56 ANAVCKLTYLQMLGYDISW-----AAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIM 110
Query: 105 VTSS-LTKDMTGKEDNYRGPAVRAL-CQITDSTM------LQAIERYMKQAIVDKVPSVS 156
+T++ + KD++ G A+ L C +T + + + K I K +
Sbjct: 111 LTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIM 170
Query: 157 SSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMV----------QYHALGLLYHVRKN 206
+ L+ +F +K + + S + V Y +L L+
Sbjct: 171 YKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMT 230
Query: 207 DRLAVNKMISKVTRHGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMV 266
+I + G +P + R+ K +E PL + I S +
Sbjct: 231 SSTNNWVLIKIIKLFGALTP----LEPRLGKKLIE--------PLTNLIHS---TSAMSL 275
Query: 267 VYEAASAIV--------NLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKH 318
+YE + ++ +P SA + V L++ L+Y + ++K+ H
Sbjct: 276 LYECVNTVIAVLISLSSGMPNHSAS-IQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTH 334
Query: 319 PSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEIS-----D 373
P +V + + + D + SI A+ L S+ ++ ++K++ + + + D
Sbjct: 335 PKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRD 394
Query: 374 EFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEG---GFEYKRAIVDCIISI--IEEN 428
E ++ S +Y ++ L + R EG G ++D I + I +
Sbjct: 395 ELLTKIIDICSQSNYQYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKF 454
Query: 429 SESKETGL---SHL----------CEFIEDC-----EFTVLATRILHLL-GQEGPKTTNP 469
+ S+ + L +HL CE + EF+ H L P+ T
Sbjct: 455 AVSQMSALLDSAHLLASSTQRNGICEVLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTL 514
Query: 470 SKYIRFIY-NRVVLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRA 528
+I+ +Y VV + + A GAQ L ++ L + V D EV++RA
Sbjct: 515 PGHIQAVYVQNVVKLYASILQQKEQAGEAEGAQAVTQL--MVDRLPQFVQSADLEVQERA 572
Query: 529 TFYLNVLEQKQKALNAGYILNGLTVSIPGLERALQQYTLEPSEKPFDLKSVPL------- 581
+ L +++ QK L V + AL L P P K VP+
Sbjct: 573 SCILQLVKHIQK-------LQAKDVPVAEEVSALFAGELNP-VAPKAQKKVPVPEGLDLD 624
Query: 582 --ATAPMAEQRTESTPITAVKQPEKVAATR---QEIFQEQLAAVPEFR----GLGPLF-K 631
P+++ +E AV E+ + E +E+LA E R P + K
Sbjct: 625 AWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEADEEELARRREARKQEQANNPFYIK 684
Query: 632 SSPEP 636
SSP P
Sbjct: 685 SSPSP 689
>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
Length = 1236
Score = 35.0 bits (79), Expect = 0.30
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Query: 285 LAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKH-----PSAVTACNLDLENLVTDSNRS 339
LA A+ +L F + ALR A + L+ +A PSAV A +L LV +S+
Sbjct: 650 LAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMH 709
Query: 340 IATLAITTLLKTGSESSIDRLMKQISSFMSEI 371
+A LA+ L T +++ L++ +SE+
Sbjct: 710 VAQLAV-DFLATVTQAQPASLVEVSGPVLSEL 740
>gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens]
Length = 1119
Score = 35.0 bits (79), Expect = 0.30
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Query: 285 LAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKH-----PSAVTACNLDLENLVTDSNRS 339
LA A+ +L F + ALR A + L+ +A PSAV A +L LV +S+
Sbjct: 557 LAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMH 616
Query: 340 IATLAITTLLKTGSESSIDRLMKQISSFMSEI 371
+A LA+ L T +++ L++ +SE+
Sbjct: 617 VAQLAV-DFLATVTQAQPASLVEVSGPVLSEL 647
>gi|33636719 translocase of inner mitochondrial membrane 44 [Homo
sapiens]
Length = 452
Score = 34.3 bits (77), Expect = 0.52
Identities = 37/148 (25%), Positives = 71/148 (47%), Gaps = 12/148 (8%)
Query: 141 ERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLL 200
+R++KQ D +P+V + + L D++K W EA + + I Q ALGL
Sbjct: 313 DRFLKQCENDIIPNVLEAMISGEL-------DILKDWCYEATYSQLAHPIQ-QAKALGLQ 364
Query: 201 YHVRKNDRLAVNKMISKVTRHG--LKSPFAYCMMIRVASKQLEEEDGSRDSPL-FDFIES 257
+H R D V+ + K+ G L F +++ V + + E +G D L ++ +
Sbjct: 365 FHSRILDIDNVDLAMGKMMEQGPVLIITFQAQLVMVVRNPKGEVVEGDPDKVLRMLYVWA 424
Query: 258 CLRNKHEMVVYEAASAIVNLPGCSAKEL 285
R++ E+ Y AA ++++ S +++
Sbjct: 425 LCRDQDELNPY-AAWRLLDISASSTEQI 451
>gi|118402596 cell division cycle protein 23 [Homo sapiens]
Length = 597
Score = 32.3 bits (72), Expect = 2.0
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
Query: 23 EKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDP 82
E S Q+ FN+T + +L +IL L NQGE TTE FF L +N P
Sbjct: 528 EASTCAQKCCAFNDTREEGKA---LLRQILQLRNQGE-TPTTEVPAPFFLPASLSANNTP 583
Query: 83 TLR 85
T R
Sbjct: 584 TRR 586
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 31.6 bits (70), Expect = 3.4
Identities = 90/426 (21%), Positives = 162/426 (38%), Gaps = 66/426 (15%)
Query: 266 VVYEAASAIV--------NLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMK 317
++YE + ++ +P SA + V L++ L+Y + ++K+
Sbjct: 184 LLYECVNTVIAVLISLSSGMPNHSAS-IQLCVQKLRILIEDSDQNLKYLGLLAMSKILKT 242
Query: 318 HPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEIS----- 372
HP +V + + + D + SI A+ L S+ ++ ++K++ + + +
Sbjct: 243 HPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYR 302
Query: 373 DEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEG---GFEYKRAIVDCIISI--IEE 427
DE ++ S +Y ++ L + R EG G ++D I + I +
Sbjct: 303 DELLTKIIDICSQSNYQYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRK 362
Query: 428 NSESKETGL---SHL----------CEFIEDC-----EFTVLATRILHLL-GQEGPKTTN 468
+ S+ + L +HL CE + EF+ H L P+ T
Sbjct: 363 FAVSQMSALLDSAHLLASSTQRNGICEVLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTT 422
Query: 469 PSKYIRFIY-NRVVLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDR 527
+I+ +Y VV + + A GAQ L ++ L + V D EV++R
Sbjct: 423 LPGHIQAVYVQNVVKLYASILQQKEQAGEAEGAQAVTQL--MVDRLPQFVQSADLEVQER 480
Query: 528 ATFYLNVLEQKQKALNAGYILNGLTVSIPGLERALQQYTLEPSEKPFDLKSVPL------ 581
A+ L +++ QK L V + AL L P P K VP+
Sbjct: 481 ASCILQLVKHIQK-------LQAKDVPVAEEVSALFAGELNP-VAPKAQKKVPVPEGLDL 532
Query: 582 ---ATAPMAEQRTESTPITAVKQPEKVAATR---QEIFQEQLAAVPEFR----GLGPLF- 630
P+++ +E AV E+ + E +E+LA E R P +
Sbjct: 533 DAWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEADEEELARRREARKQEQANNPFYI 592
Query: 631 KSSPEP 636
KSSP P
Sbjct: 593 KSSPSP 598
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 31.6 bits (70), Expect = 3.4
Identities = 45/186 (24%), Positives = 64/186 (34%), Gaps = 28/186 (15%)
Query: 551 LTVSIPGLERALQQYTLEPSEKPFDLKSVPLATAPMAEQRTESTPITAVKQPEKVAATRQ 610
LT + P ++ ++ LEPS L + P E+ S PI +PE +
Sbjct: 473 LTPTHPSVKGEKEENMLEPS---ISLSEPLMLEEPEKEEIETSLPIAITPEPEDSNLVEE 529
Query: 611 EIFQEQLAAVP-------------------EFRGLGPLFKSSPEPVALTESETEYVIR-C 650
EI + P E L L SSPE VAL+E E E +
Sbjct: 530 EIVELDYPESPLVSEKPFPPHMSPEVEHKEEELILPLLAASSPEHVALSEEEREEIASVS 589
Query: 651 TKHTFTNHMVFQFDCTNTLNDQTLENVTVQMEPTEAYEVLCYVPARSLPYNQPGTCYTLV 710
T F + D + L +Q E V P E + S N+ Y+
Sbjct: 590 TGSAFVSEYSVPQDLNHELQEQEGEPV-----PPSNVEAIAEHAVLSEEENEEFEAYSPA 644
Query: 711 ALPKED 716
A P +
Sbjct: 645 AAPTSE 650
>gi|222418587 hypothetical protein LOC57495 [Homo sapiens]
Length = 1742
Score = 31.2 bits (69), Expect = 4.4
Identities = 15/42 (35%), Positives = 23/42 (54%)
Query: 370 EISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGF 411
EISDE K + A+ L +K KH+ +LF+ + +E F
Sbjct: 202 EISDEIKKIFKAAVKLLHEKGKMKHSQAKRYLFSAIEDEFDF 243
>gi|12025663 ubiquitin-conjugating enzyme E2 variant 1 isoform c
[Homo sapiens]
Length = 103
Score = 30.8 bits (68), Expect = 5.7
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 449 TVLATRILHLLGQEGPKTTNPSKYIRFI----YNRVVLEHEEVRAGAVSALAKFGAQNEE 504
T+ RI L + GPK ++RF+ N V + V A+S LAK+ QN
Sbjct: 14 TIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKW--QNSY 71
Query: 505 MLPSILVLLKRCVMDDDN 522
+ +L L+R +M +N
Sbjct: 72 SIKVVLQELRRLMMSKEN 89
>gi|40806164 ubiquitin-conjugating enzyme E2 variant 1 isoform a
[Homo sapiens]
Length = 170
Score = 30.8 bits (68), Expect = 5.7
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 449 TVLATRILHLLGQEGPKTTNPSKYIRFI----YNRVVLEHEEVRAGAVSALAKFGAQNEE 504
T+ RI L + GPK ++RF+ N V + V A+S LAK+ QN
Sbjct: 81 TIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKW--QNSY 138
Query: 505 MLPSILVLLKRCVMDDDN 522
+ +L L+R +M +N
Sbjct: 139 SIKVVLQELRRLMMSKEN 156
>gi|40806190 TMEM189-UBE2V1 readthrough transcript [Homo sapiens]
Length = 370
Score = 30.8 bits (68), Expect = 5.7
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 449 TVLATRILHLLGQEGPKTTNPSKYIRFI----YNRVVLEHEEVRAGAVSALAKFGAQNEE 504
T+ RI L + GPK ++RF+ N V + V A+S LAK+ QN
Sbjct: 281 TIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKW--QNSY 338
Query: 505 MLPSILVLLKRCVMDDDN 522
+ +L L+R +M +N
Sbjct: 339 SIKVVLQELRRLMMSKEN 356
>gi|130484567 HFM1 protein [Homo sapiens]
Length = 1435
Score = 30.8 bits (68), Expect = 5.7
Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 13/106 (12%)
Query: 765 QKVMKLNFEAA---WDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVP- 820
++V+ +NFE WD+ DE + +F+ T KT GN + R K+P
Sbjct: 1257 KEVLNVNFELGNEVWDDFDDENLEVTSFSTDTEKTKISGFGNT-----LSSSTRGSKLPL 1311
Query: 821 -DNKNTHTLLLAGVFRGGHDILVRSRLLLLDTVTMQVTARSLEELP 865
++K+ ++ F H++ S + L ++ + +A S+ +LP
Sbjct: 1312 QESKSKFQREMSNSFVSSHEM---SDISLSNSAMPKFSASSMTKLP 1354
>gi|73765546 ubiquitin-conjugating enzyme E2 variant 1 isoform d
[Homo sapiens]
Length = 147
Score = 30.8 bits (68), Expect = 5.7
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 449 TVLATRILHLLGQEGPKTTNPSKYIRFI----YNRVVLEHEEVRAGAVSALAKFGAQNEE 504
T+ RI L + GPK ++RF+ N V + V A+S LAK+ QN
Sbjct: 58 TIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKW--QNSY 115
Query: 505 MLPSILVLLKRCVMDDDN 522
+ +L L+R +M +N
Sbjct: 116 SIKVVLQELRRLMMSKEN 133
>gi|40806167 ubiquitin-conjugating enzyme E2 variant 1 isoform a
[Homo sapiens]
Length = 170
Score = 30.8 bits (68), Expect = 5.7
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 449 TVLATRILHLLGQEGPKTTNPSKYIRFI----YNRVVLEHEEVRAGAVSALAKFGAQNEE 504
T+ RI L + GPK ++RF+ N V + V A+S LAK+ QN
Sbjct: 81 TIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKW--QNSY 138
Query: 505 MLPSILVLLKRCVMDDDN 522
+ +L L+R +M +N
Sbjct: 139 SIKVVLQELRRLMMSKEN 156
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,652,905
Number of Sequences: 37866
Number of extensions: 1298977
Number of successful extensions: 3434
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 3401
Number of HSP's gapped (non-prelim): 64
length of query: 874
length of database: 18,247,518
effective HSP length: 111
effective length of query: 763
effective length of database: 14,044,392
effective search space: 10715871096
effective search space used: 10715871096
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.