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Search of human proteins with 23510335
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23510335 inositol hexakisphosphate kinase 1 isoform 1 [Homo
sapiens]
(441 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23510335 inositol hexakisphosphate kinase 1 isoform 1 [Homo s... 901 0.0
gi|55769518 inositol hexakisphosphate kinase 1 isoform 2 [Homo s... 565 e-161
gi|218777830 inositol hexakisphosphate kinase 3 [Homo sapiens] 405 e-113
gi|55769530 inositol hexakisphosphate kinase 3 [Homo sapiens] 405 e-113
gi|55769520 inositol hexaphosphate kinase 2 isoform a [Homo sapi... 389 e-108
gi|56237025 inositol hexaphosphate kinase 2 isoform a [Homo sapi... 389 e-108
gi|22726201 inositol polyphosphate multikinase [Homo sapiens] 95 1e-19
gi|226051970 inositol hexaphosphate kinase 2 isoform c [Homo sap... 90 5e-18
gi|226051954 inositol hexaphosphate kinase 2 isoform c [Homo sap... 90 5e-18
gi|55769524 inositol hexaphosphate kinase 2 isoform b [Homo sapi... 88 1e-17
gi|55769522 inositol hexaphosphate kinase 2 isoform b [Homo sapi... 88 1e-17
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 36 0.080
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 36 0.080
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 35 0.10
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 35 0.14
gi|194097341 period 1 [Homo sapiens] 33 0.52
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom... 33 0.52
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom... 33 0.52
gi|6005948 WW domain-containing binding protein 4 [Homo sapiens] 33 0.67
gi|221316599 chromogranin B precursor [Homo sapiens] 32 0.88
gi|145864459 diacylglycerol O-acyltransferase 1 [Homo sapiens] 32 0.88
gi|164414421 hypothetical protein LOC9750 isoform 1 [Homo sapiens] 32 1.1
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 32 1.1
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 32 1.1
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 32 1.1
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 32 1.5
gi|52426743 cisplatin resistance-associated overexpressed protei... 32 1.5
gi|19923485 cisplatin resistance-associated overexpressed protei... 32 1.5
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 31 2.0
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 31 2.0
>gi|23510335 inositol hexakisphosphate kinase 1 isoform 1 [Homo
sapiens]
Length = 441
Score = 901 bits (2328), Expect = 0.0
Identities = 441/441 (100%), Positives = 441/441 (100%)
Query: 1 MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYE 60
MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYE
Sbjct: 1 MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYE 60
Query: 61 SLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRR 120
SLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRR
Sbjct: 61 SLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRR 120
Query: 121 SLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGLSSEKISH 180
SLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGLSSEKISH
Sbjct: 121 SLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGLSSEKISH 180
Query: 181 NPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEK 240
NPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEK
Sbjct: 181 NPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEK 240
Query: 241 AARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNG 300
AARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNG
Sbjct: 241 AARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNG 300
Query: 301 LDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKH 360
LDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKH
Sbjct: 301 LDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKH 360
Query: 361 LDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDR 420
LDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDR
Sbjct: 361 LDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDR 420
Query: 421 GYVFGLENLISIMEQMRDENQ 441
GYVFGLENLISIMEQMRDENQ
Sbjct: 421 GYVFGLENLISIMEQMRDENQ 441
>gi|55769518 inositol hexakisphosphate kinase 1 isoform 2 [Homo
sapiens]
Length = 276
Score = 565 bits (1456), Expect = e-161
Identities = 276/276 (100%), Positives = 276/276 (100%)
Query: 166 MLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDL 225
MLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDL
Sbjct: 1 MLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDL 60
Query: 226 KMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLS 285
KMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLS
Sbjct: 61 KMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLS 120
Query: 286 IEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECR 345
IEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECR
Sbjct: 121 IEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECR 180
Query: 346 AESCLDRRSEMRLKHLDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTF 405
AESCLDRRSEMRLKHLDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTF
Sbjct: 181 AESCLDRRSEMRLKHLDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTF 240
Query: 406 KGFRDDPTVHDGPDRGYVFGLENLISIMEQMRDENQ 441
KGFRDDPTVHDGPDRGYVFGLENLISIMEQMRDENQ
Sbjct: 241 KGFRDDPTVHDGPDRGYVFGLENLISIMEQMRDENQ 276
>gi|218777830 inositol hexakisphosphate kinase 3 [Homo sapiens]
Length = 410
Score = 405 bits (1040), Expect = e-113
Identities = 220/439 (50%), Positives = 288/439 (65%), Gaps = 48/439 (10%)
Query: 14 KNASRAGDR--GVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTP 71
+N++ AGD GV LEPF+HQVGGH S+M+YD+HTVCKPL+SREQRFYESLP MK FTP
Sbjct: 4 QNSADAGDMRAGVQLEPFLHQVGGHMSVMKYDEHTVCKPLVSREQRFYESLPLAMKRFTP 63
Query: 72 EYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRRSLHRSGSGSDH 131
+YKG V+V DS G+++LVA P ES+ + T + +++ +GS
Sbjct: 64 QYKGTVTVHLWKDSTGHLSLVANPVKESQEPFKVSTESAAVAIWQTLQQTTGSNGS---- 119
Query: 132 KEEKASLSLETSESSQEAKSPK-------VELHSHSEVP-FQMLDGNSGLSSEKISHNPW 183
+L +Q A+SPK + H P F +++ +G E+ S NPW
Sbjct: 120 -----DCTLAQWPHAQLARSPKESPAKALLRSEPHLNTPAFSLVEDTNGNQVERKSFNPW 174
Query: 184 SLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAAR 243
L+CH+ L+R+ SE + K ++FLLLENVV + +PCVLDLKMGTRQHGDDAS EK AR
Sbjct: 175 GLQCHQAHLTRLCSEYPENKRHRFLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKAR 234
Query: 244 QMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDL 303
MRKC QSTSA LGVR+CGMQVYQ D ++LC++KYYGR LS+EGFR ALYQ+LHNG L
Sbjct: 235 HMRKCAQSTSACLGVRICGMQVYQTDKKYFLCKDKYYGRKLSVEGFRQALYQFLHNGSHL 294
Query: 304 RRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKHLDM 363
RR+L EPIL +LR L +V+ Q+SYRFYSSSLLVIYDG+E
Sbjct: 295 RRELLEPILHQLRALLSVIRSQSSYRFYSSSLLVIYDGQE-------------------- 334
Query: 364 VLPEVASSCGPSTSPSNTSPEAGPSSQP----KVDVRMIDFAHSTFKGFRDDPTVHDGPD 419
PE A P + + +P+A S P KVD+RMIDFAH+T+KG+ ++ T +DGPD
Sbjct: 335 -PPERA----PGSPHPHEAPQAAHGSSPGGLTKVDIRMIDFAHTTYKGYWNEHTTYDGPD 389
Query: 420 RGYVFGLENLISIMEQMRD 438
GY+FGLENLI I++ +++
Sbjct: 390 PGYIFGLENLIRILQDIQE 408
>gi|55769530 inositol hexakisphosphate kinase 3 [Homo sapiens]
Length = 410
Score = 405 bits (1040), Expect = e-113
Identities = 220/439 (50%), Positives = 288/439 (65%), Gaps = 48/439 (10%)
Query: 14 KNASRAGDR--GVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTP 71
+N++ AGD GV LEPF+HQVGGH S+M+YD+HTVCKPL+SREQRFYESLP MK FTP
Sbjct: 4 QNSADAGDMRAGVQLEPFLHQVGGHMSVMKYDEHTVCKPLVSREQRFYESLPLAMKRFTP 63
Query: 72 EYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRRSLHRSGSGSDH 131
+YKG V+V DS G+++LVA P ES+ + T + +++ +GS
Sbjct: 64 QYKGTVTVHLWKDSTGHLSLVANPVKESQEPFKVSTESAAVAIWQTLQQTTGSNGS---- 119
Query: 132 KEEKASLSLETSESSQEAKSPK-------VELHSHSEVP-FQMLDGNSGLSSEKISHNPW 183
+L +Q A+SPK + H P F +++ +G E+ S NPW
Sbjct: 120 -----DCTLAQWPHAQLARSPKESPAKALLRSEPHLNTPAFSLVEDTNGNQVERKSFNPW 174
Query: 184 SLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAAR 243
L+CH+ L+R+ SE + K ++FLLLENVV + +PCVLDLKMGTRQHGDDAS EK AR
Sbjct: 175 GLQCHQAHLTRLCSEYPENKRHRFLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKAR 234
Query: 244 QMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDL 303
MRKC QSTSA LGVR+CGMQVYQ D ++LC++KYYGR LS+EGFR ALYQ+LHNG L
Sbjct: 235 HMRKCAQSTSACLGVRICGMQVYQTDKKYFLCKDKYYGRKLSVEGFRQALYQFLHNGSHL 294
Query: 304 RRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKHLDM 363
RR+L EPIL +LR L +V+ Q+SYRFYSSSLLVIYDG+E
Sbjct: 295 RRELLEPILHQLRALLSVIRSQSSYRFYSSSLLVIYDGQE-------------------- 334
Query: 364 VLPEVASSCGPSTSPSNTSPEAGPSSQP----KVDVRMIDFAHSTFKGFRDDPTVHDGPD 419
PE A P + + +P+A S P KVD+RMIDFAH+T+KG+ ++ T +DGPD
Sbjct: 335 -PPERA----PGSPHPHEAPQAAHGSSPGGLTKVDIRMIDFAHTTYKGYWNEHTTYDGPD 389
Query: 420 RGYVFGLENLISIMEQMRD 438
GY+FGLENLI I++ +++
Sbjct: 390 PGYIFGLENLIRILQDIQE 408
>gi|55769520 inositol hexaphosphate kinase 2 isoform a [Homo
sapiens]
Length = 426
Score = 389 bits (999), Expect = e-108
Identities = 207/430 (48%), Positives = 281/430 (65%), Gaps = 31/430 (7%)
Query: 22 RGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVSVCF 81
+GVLLEPF+HQVGGHS ++R+++ T+CKPL+ RE +FYE+LP EM++FTP+YKGVVSV F
Sbjct: 15 KGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRKFTPQYKGVVSVRF 74
Query: 82 EGDSDGYINLVAYPY---------VESETVEQDDTTEREQPRRKHSRRSLHRSGSG--SD 130
E D D + L+AYP V++ E R +KH ++
Sbjct: 75 EEDEDRNLCLIAYPLKGDHGIVDIVDNSDCEPKSKLLRWTTNKKHHVLETEKTPKDWVRQ 134
Query: 131 HKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGLSSEKISHNPWSLRCHKQ 190
H++E+ S + E + K SEV + ++ +SS+ +NPWS++CH+Q
Sbjct: 135 HRKEEKMKSHKLEEEFEWLKK--------SEVLYYTVEKKGNISSQLKHYNPWSMKCHQQ 186
Query: 191 QLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQ 250
QL RM+ +K R YKF+LLEN+ ++ PCVLDLKMGTRQHGDDAS EKAA Q+RKC+Q
Sbjct: 187 QLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQ 246
Query: 251 STSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEP 310
STSA +GVRVCGMQVYQ +G + NKY+GR LS++GF+ AL+Q+ HNG LRR+L P
Sbjct: 247 STSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLRRELLGP 306
Query: 311 ILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKHLDMVLPEVAS 370
+L KL LKAVLERQ SYRFYSSSLLVIYDGKE R E LD +E L +++
Sbjct: 307 VLKKLTELKAVLERQESYRFYSSSLLVIYDGKE-RPEVVLDSDAE--------DLEDLSE 357
Query: 371 SCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDRGYVFGLENLI 430
++ + G SS VDVRMIDFAH+T + + +D VH+G D GY+FGL++LI
Sbjct: 358 ESADESAGAYAYKPIGASS---VDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQSLI 414
Query: 431 SIMEQMRDEN 440
I+ ++ +E+
Sbjct: 415 DIVTEISEES 424
>gi|56237025 inositol hexaphosphate kinase 2 isoform a [Homo
sapiens]
Length = 426
Score = 389 bits (999), Expect = e-108
Identities = 207/430 (48%), Positives = 281/430 (65%), Gaps = 31/430 (7%)
Query: 22 RGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVSVCF 81
+GVLLEPF+HQVGGHS ++R+++ T+CKPL+ RE +FYE+LP EM++FTP+YKGVVSV F
Sbjct: 15 KGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRKFTPQYKGVVSVRF 74
Query: 82 EGDSDGYINLVAYPY---------VESETVEQDDTTEREQPRRKHSRRSLHRSGSG--SD 130
E D D + L+AYP V++ E R +KH ++
Sbjct: 75 EEDEDRNLCLIAYPLKGDHGIVDIVDNSDCEPKSKLLRWTTNKKHHVLETEKTPKDWVRQ 134
Query: 131 HKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGLSSEKISHNPWSLRCHKQ 190
H++E+ S + E + K SEV + ++ +SS+ +NPWS++CH+Q
Sbjct: 135 HRKEEKMKSHKLEEEFEWLKK--------SEVLYYTVEKKGNISSQLKHYNPWSMKCHQQ 186
Query: 191 QLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQ 250
QL RM+ +K R YKF+LLEN+ ++ PCVLDLKMGTRQHGDDAS EKAA Q+RKC+Q
Sbjct: 187 QLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQ 246
Query: 251 STSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEP 310
STSA +GVRVCGMQVYQ +G + NKY+GR LS++GF+ AL+Q+ HNG LRR+L P
Sbjct: 247 STSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLRRELLGP 306
Query: 311 ILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKHLDMVLPEVAS 370
+L KL LKAVLERQ SYRFYSSSLLVIYDGKE R E LD +E L +++
Sbjct: 307 VLKKLTELKAVLERQESYRFYSSSLLVIYDGKE-RPEVVLDSDAE--------DLEDLSE 357
Query: 371 SCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDRGYVFGLENLI 430
++ + G SS VDVRMIDFAH+T + + +D VH+G D GY+FGL++LI
Sbjct: 358 ESADESAGAYAYKPIGASS---VDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQSLI 414
Query: 431 SIMEQMRDEN 440
I+ ++ +E+
Sbjct: 415 DIVTEISEES 424
>gi|22726201 inositol polyphosphate multikinase [Homo sapiens]
Length = 416
Score = 94.7 bits (234), Expect = 1e-19
Identities = 49/148 (33%), Positives = 82/148 (55%), Gaps = 2/148 (1%)
Query: 207 FLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVY 266
+L LE+V H F PC++D+K+G + + AS+EK +Q+ K +G V GM+VY
Sbjct: 127 YLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSK--YPLMEEIGFLVLGMRVY 184
Query: 267 QLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQA 326
+ + Y N++YGR L+ E ++ + ++ HNG LR+D + K+ + E Q
Sbjct: 185 HVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWFENQK 244
Query: 327 SYRFYSSSLLVIYDGKECRAESCLDRRS 354
FY+SSLL +Y+G + L+ R+
Sbjct: 245 QLNFYASSLLFVYEGSSQPTTTKLNDRT 272
Score = 35.0 bits (79), Expect = 0.14
Identities = 20/47 (42%), Positives = 29/47 (61%), Gaps = 9/47 (19%)
Query: 392 KVDVRMIDFAHSTFKGFRDDPTVHDGPDRGYVFGLENLISIMEQMRD 438
+V+VRMIDFAH T+ D GYV+GL++LIS++ + D
Sbjct: 378 EVEVRMIDFAHVF-----PSNTI----DEGYVYGLKHLISVLRSILD 415
>gi|226051970 inositol hexaphosphate kinase 2 isoform c [Homo
sapiens]
Length = 87
Score = 89.7 bits (221), Expect = 5e-18
Identities = 36/57 (63%), Positives = 51/57 (89%)
Query: 22 RGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVS 78
+GVLLEPF+HQVGGHS ++R+++ T+CKPL+ RE +FYE+LP EM++FTP+YKG +S
Sbjct: 15 KGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRKFTPQYKGDIS 71
>gi|226051954 inositol hexaphosphate kinase 2 isoform c [Homo
sapiens]
Length = 87
Score = 89.7 bits (221), Expect = 5e-18
Identities = 36/57 (63%), Positives = 51/57 (89%)
Query: 22 RGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVS 78
+GVLLEPF+HQVGGHS ++R+++ T+CKPL+ RE +FYE+LP EM++FTP+YKG +S
Sbjct: 15 KGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRKFTPQYKGDIS 71
>gi|55769524 inositol hexaphosphate kinase 2 isoform b [Homo
sapiens]
Length = 97
Score = 88.2 bits (217), Expect = 1e-17
Identities = 35/54 (64%), Positives = 49/54 (90%)
Query: 22 RGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKG 75
+GVLLEPF+HQVGGHS ++R+++ T+CKPL+ RE +FYE+LP EM++FTP+YKG
Sbjct: 15 KGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRKFTPQYKG 68
>gi|55769522 inositol hexaphosphate kinase 2 isoform b [Homo
sapiens]
Length = 97
Score = 88.2 bits (217), Expect = 1e-17
Identities = 35/54 (64%), Positives = 49/54 (90%)
Query: 22 RGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKG 75
+GVLLEPF+HQVGGHS ++R+++ T+CKPL+ RE +FYE+LP EM++FTP+YKG
Sbjct: 15 KGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRKFTPQYKG 68
>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
Length = 2382
Score = 35.8 bits (81), Expect = 0.080
Identities = 50/223 (22%), Positives = 83/223 (37%), Gaps = 44/223 (19%)
Query: 25 LLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKG--------- 75
LL+P + +G +++ + + PL S + Y+ PP + P+Y G
Sbjct: 914 LLQPAVQSMGIPANLGQAAE----VPLSSGDV-LYQGFPPRLP---PQYPGDSNIAPSSN 965
Query: 76 VVSVCFEGD------------SDGYINLVAYPYVESET------------VEQDDTTERE 111
V SVC + GY V PYVES V Q + +
Sbjct: 966 VASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQ 1025
Query: 112 QPRRKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNS 171
P S++++ S G +++ ++++Q +HS+V M DGN
Sbjct: 1026 APTTS-SQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNE 1084
Query: 172 GLSSEKISHNPWSLRCH--KQQLSRMRSESKDRKLYKFLLLEN 212
+ S H + + H K SR R E R + L + N
Sbjct: 1085 NVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSN 1127
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 35.8 bits (81), Expect = 0.080
Identities = 24/117 (20%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Query: 99 SETVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASL-SLETSESSQEAKSPKVELH 157
S + + +D +++ RRK + ++S S H+ E S S++ + S++ + ++
Sbjct: 115 SSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVR 174
Query: 158 SHSEVPFQMLDGNSGLSSEKISHNPW--------SLRCHKQQLSRMRSESKDRKLYK 206
S S+ + + LSSE S + + RC +++ ++ + + K +K +K
Sbjct: 175 SLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHK 231
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 35.4 bits (80), Expect = 0.10
Identities = 39/159 (24%), Positives = 62/159 (38%), Gaps = 21/159 (13%)
Query: 99 SETVEQDDTTEREQPRRKHSRRSLHRS----------GSGSDHKEEKASLSLET--SESS 146
S + E+D + ER + R + RRS RS G+ S E ++ +T ESS
Sbjct: 71 SRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESS 130
Query: 147 QEAKSPKVELHSHSEVPFQMLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSESKDRKLYK 206
+E K K + E D N L E +R K+++ + R E + + +
Sbjct: 131 KEKKKDKDDKEDEKEKDAGNFDQNK-LEEE--------MRKRKERVEKWREEQRKKAMEN 181
Query: 207 FLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQM 245
L+ + K L+ D A AEK +M
Sbjct: 182 IGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEM 220
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 35.0 bits (79), Expect = 0.14
Identities = 43/158 (27%), Positives = 67/158 (42%), Gaps = 30/158 (18%)
Query: 110 REQPRRKHSRRSLHRSGSG-SDHKEEKA-------SLSLETSESSQEAKSPKVELHSHSE 161
R + R +HSR+S RSGS S H + ++ S S S S ++S K + S S+
Sbjct: 193 RSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSK 252
Query: 162 VPFQMLDGNSGLS--------SEKISHNPWSLRCHKQQLSRMRSESKDRKLYKFLLLENV 213
+ ++G S EKI +N + + SR +S+SK R + +E
Sbjct: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVE-- 310
Query: 214 VHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQS 251
+ K G+ G S EK+ RQ R +S
Sbjct: 311 ----------EEKRGSVSRG--RSQEKSLRQSRSRSRS 336
>gi|194097341 period 1 [Homo sapiens]
Length = 1290
Score = 33.1 bits (74), Expect = 0.52
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 11/86 (12%)
Query: 115 RKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGLS 174
R S+RS H S SG+ K S LET+ESS+ +S S P S LS
Sbjct: 63 RGASQRSSHSSSSGNG----KDSALLETTESSKST-------NSQSPSPPSSSIAYSLLS 111
Query: 175 SEKISHNPWSLRCHKQQLSRMRSESK 200
+ NP + C +Q +R R++ +
Sbjct: 112 ASSEQDNPSTSGCSSEQSARARTQKE 137
>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
sapiens]
Length = 1108
Score = 33.1 bits (74), Expect = 0.52
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 3/147 (2%)
Query: 34 GGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVA 93
G +S M + + R+ E PE+ + E+ G + +GDSD +L
Sbjct: 957 GSYSQHMNHRYSYCKREAEERDSTEQEEAGPEI--LSNEHVGARASPSQGDSDERESLTR 1014
Query: 94 YPYVESETVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASLSLETSES-SQEAKSP 152
+SE E+++ E E+ + + + +EE +E +E+ +EAK+
Sbjct: 1015 EEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTE 1074
Query: 153 KVELHSHSEVPFQMLDGNSGLSSEKIS 179
+ +E L G SSE++S
Sbjct: 1075 GLMKDDRAESQASSLGQKVGESSEQVS 1101
>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
sapiens]
Length = 1124
Score = 33.1 bits (74), Expect = 0.52
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 3/147 (2%)
Query: 34 GGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVA 93
G +S M + + R+ E PE+ + E+ G + +GDSD +L
Sbjct: 973 GSYSQHMNHRYSYCKREAEERDSTEQEEAGPEI--LSNEHVGARASPSQGDSDERESLTR 1030
Query: 94 YPYVESETVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASLSLETSES-SQEAKSP 152
+SE E+++ E E+ + + + +EE +E +E+ +EAK+
Sbjct: 1031 EEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTE 1090
Query: 153 KVELHSHSEVPFQMLDGNSGLSSEKIS 179
+ +E L G SSE++S
Sbjct: 1091 GLMKDDRAESQASSLGQKVGESSEQVS 1117
>gi|6005948 WW domain-containing binding protein 4 [Homo sapiens]
Length = 376
Score = 32.7 bits (73), Expect = 0.67
Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 24/97 (24%)
Query: 84 DSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASLSLETS 143
DSDG E E E +TE E+P+ K ++ + G +++ S+ + S
Sbjct: 228 DSDG----------EQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNS 277
Query: 144 ESSQEAKSP--------------KVELHSHSEVPFQM 166
S E KS K E+ SH EV ++
Sbjct: 278 LGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLEL 314
>gi|221316599 chromogranin B precursor [Homo sapiens]
Length = 677
Score = 32.3 bits (72), Expect = 0.88
Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 4/72 (5%)
Query: 98 ESETVEQDDTTE----REQPRRKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEAKSPK 153
ESE E+D T+E R +PR H R RS G E+ E SE S + +
Sbjct: 262 ESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASL 321
Query: 154 VELHSHSEVPFQ 165
E H ++
Sbjct: 322 GEKRDHHSTHYR 333
>gi|145864459 diacylglycerol O-acyltransferase 1 [Homo sapiens]
Length = 488
Score = 32.3 bits (72), Expect = 0.88
Identities = 26/86 (30%), Positives = 34/86 (39%), Gaps = 15/86 (17%)
Query: 114 RRKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGL 173
RR SR S H G + +EE A P V + P DG++G+
Sbjct: 10 RRTGSRPSSHGGGGPAAAEEEVRDA----------AAGPDVGAAGDAPAPAPNKDGDAGV 59
Query: 174 SSEKISHNPWSLRCHKQQLSRMRSES 199
S W LRCH+ Q S S+S
Sbjct: 60 GS-----GHWELRCHRLQDSLFSSDS 80
>gi|164414421 hypothetical protein LOC9750 isoform 1 [Homo sapiens]
Length = 1068
Score = 32.0 bits (71), Expect = 1.1
Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 14/117 (11%)
Query: 36 HSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYP 95
+ +M DD CKP +SR + SL E + ++ E D D N+
Sbjct: 629 NQEVMNLDDILKCKPAVSRSRSSSLSLTVESALESFDFLNTSDFDEEEDGDEVCNVGG-- 686
Query: 96 YVESETVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEAKSP 152
+++V D TE KHS RS+H G H E +L+ +T + A SP
Sbjct: 687 --GADSVFSDTETE------KHSYRSVHPEARG--HLSE--ALTEDTGVGTSVAGSP 731
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 32.0 bits (71), Expect = 1.1
Identities = 24/107 (22%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 99 SETVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASL-SLETSESSQEAKSPKVELH 157
S + + +D +++ RRK + H+S S + E S SL+ + S++ + ++
Sbjct: 106 SSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIK 165
Query: 158 SHSEVPFQMLDGNSGLSSEKISHNPW--SLRCHKQQLSRMRSESKDR 202
S+ +M + LSSE +S + + +R K++ S R ++ ++
Sbjct: 166 GLSK-KRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEK 211
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 32.0 bits (71), Expect = 1.1
Identities = 24/107 (22%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 99 SETVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASL-SLETSESSQEAKSPKVELH 157
S + + +D +++ RRK + H+S S + E S SL+ + S++ + ++
Sbjct: 116 SSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIK 175
Query: 158 SHSEVPFQMLDGNSGLSSEKISHNPW--SLRCHKQQLSRMRSESKDR 202
S+ +M + LSSE +S + + +R K++ S R ++ ++
Sbjct: 176 GLSK-KRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEK 221
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 32.0 bits (71), Expect = 1.1
Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 8/62 (12%)
Query: 98 ESETVEQDDTTEREQPRRKHSRRSLHRSGSG--------SDHKEEKASLSLETSESSQEA 149
+S + E D + E R+KH SGSG S+ +EE+ S + +ES E
Sbjct: 125 DSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEP 184
Query: 150 KS 151
K+
Sbjct: 185 KN 186
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 31.6 bits (70), Expect = 1.5
Identities = 23/113 (20%), Positives = 44/113 (38%), Gaps = 5/113 (4%)
Query: 90 NLVAYPYVESETVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEA 149
N V E+ E+++ E E+ GS+ EE +S E
Sbjct: 521 NKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLD 580
Query: 150 KSPKVELHSHSEVPFQMLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSESKDR 202
K P E+ S SE D + + E+ +++ R K++L ++ + ++
Sbjct: 581 KKPSKEMSSDSE-----YDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEK 628
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 31.6 bits (70), Expect = 1.5
Identities = 35/166 (21%), Positives = 62/166 (37%), Gaps = 10/166 (6%)
Query: 41 RYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESE 100
R DDH L+ ++ Y + ++E + + E D D + E E
Sbjct: 207 RVDDH-----LMGKQHMGYAKIKATVEELKEKLRKRTE---EPDRDERLKKEKQEREERE 258
Query: 101 TVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHS 160
+ + ERE+ RR+ + ++ S S +S +S S + H S
Sbjct: 259 KEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRD-HKRS 317
Query: 161 EVPFQMLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSESKDRKLYK 206
+ + + SH+ + + R RS+S+DRK YK
Sbjct: 318 RSRERRRSRSRDRRRSR-SHDRSERKHRSRSRDRRRSKSRDRKSYK 362
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 31.6 bits (70), Expect = 1.5
Identities = 35/166 (21%), Positives = 62/166 (37%), Gaps = 10/166 (6%)
Query: 41 RYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESE 100
R DDH L+ ++ Y + ++E + + E D D + E E
Sbjct: 207 RVDDH-----LMGKQHMGYAKIKATVEELKEKLRKRTE---EPDRDERLKKEKQEREERE 258
Query: 101 TVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHS 160
+ + ERE+ RR+ + ++ S S +S +S S + H S
Sbjct: 259 KEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRD-HKRS 317
Query: 161 EVPFQMLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSESKDRKLYK 206
+ + + SH+ + + R RS+S+DRK YK
Sbjct: 318 RSRERRRSRSRDRRRSR-SHDRSERKHRSRSRDRRRSKSRDRKSYK 362
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 31.2 bits (69), Expect = 2.0
Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 14/110 (12%)
Query: 110 REQPRRKHSRRSLHRS--GSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVP---- 163
RE+ R + RRS S SD E++ E + +E ++ + + S
Sbjct: 754 RERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAGDR 813
Query: 164 FQMLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSESKD-RKLYKFLLLEN 212
+ L G SG S P+S R K +S D +KLY+ +L EN
Sbjct: 814 YDSLLGRSGSYSYLEERKPYSSRLEK-------DDSTDFKKLYEQILAEN 856
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 31.2 bits (69), Expect = 2.0
Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 14/110 (12%)
Query: 110 REQPRRKHSRRSLHRS--GSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVP---- 163
RE+ R + RRS S SD E++ E + +E ++ + + S
Sbjct: 841 RERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAGDR 900
Query: 164 FQMLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSESKD-RKLYKFLLLEN 212
+ L G SG S P+S R K +S D +KLY+ +L EN
Sbjct: 901 YDSLLGRSGSYSYLEERKPYSSRLEK-------DDSTDFKKLYEQILAEN 943
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,336,632
Number of Sequences: 37866
Number of extensions: 790019
Number of successful extensions: 3583
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 3461
Number of HSP's gapped (non-prelim): 173
length of query: 441
length of database: 18,247,518
effective HSP length: 105
effective length of query: 336
effective length of database: 14,271,588
effective search space: 4795253568
effective search space used: 4795253568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.