BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|23463326 POU domain class 5, transcription factor 2 [Homo sapiens] (328 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|23463326 POU domain class 5, transcription factor 2 [Homo sap... 687 0.0 gi|42560248 POU domain, class 5, transcription factor 1 isoform ... 274 9e-74 gi|227430410 POU class 5 homeobox 1B [Homo sapiens] 256 2e-68 gi|116235491 POU domain, class 5, transcription factor 1 isoform... 204 7e-53 gi|110624763 POU domain, class 3, transcription factor 4 [Homo s... 144 1e-34 gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 142 3e-34 gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa... 141 7e-34 gi|110624765 POU domain, class 3, transcription factor 1 [Homo s... 139 3e-33 gi|148664218 POU transcription factor [Homo sapiens] 122 6e-28 gi|42476164 POU class 2 homeobox 1 [Homo sapiens] 121 7e-28 gi|4505959 POU domain, class 2, transcription factor 2 [Homo sap... 121 1e-27 gi|170650730 pituitary specific transcription factor 1 isoform b... 105 7e-23 gi|4505955 pituitary specific transcription factor 1 isoform alp... 105 7e-23 gi|110347455 Brn3b POU domain transcription factor [Homo sapiens] 100 3e-21 gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 99 4e-21 gi|4505965 POU class 4 homeobox 3 [Homo sapiens] 99 5e-21 gi|223890225 POU class 6 homeobox 1 [Homo sapiens] 99 7e-21 gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 70 2e-12 gi|113416879 PREDICTED: hypothetical protein [Homo sapiens] 36 0.041 gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens] 35 0.12 gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 34 0.16 gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 33 0.27 gi|210147470 NK2 transcription factor related, locus 6 [Homo sap... 33 0.27 gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens] 33 0.35 gi|157426823 NK2 homeobox 4 [Homo sapiens] 33 0.45 gi|4758168 distal-less homeobox 2 [Homo sapiens] 32 0.59 gi|170784824 paired box 4 [Homo sapiens] 32 0.59 gi|4885363 goosecoid homeobox 2 [Homo sapiens] 32 0.59 gi|4504465 homeobox B2 [Homo sapiens] 32 0.59 gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] 32 0.77 >gi|23463326 POU domain class 5, transcription factor 2 [Homo sapiens] Length = 328 Score = 687 bits (1773), Expect = 0.0 Identities = 328/328 (100%), Positives = 328/328 (100%) Query: 1 MAGHRPSNHFCPLPGSGGGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPDV 60 MAGHRPSNHFCPLPGSGGGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPDV Sbjct: 1 MAGHRPSNHFCPLPGSGGGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPDV 60 Query: 61 WRIPLGPLPHEFRGWIAPCRPRLGASEAGDWLRRPSEGALPGPYIALRSIPKLPPPEDIS 120 WRIPLGPLPHEFRGWIAPCRPRLGASEAGDWLRRPSEGALPGPYIALRSIPKLPPPEDIS Sbjct: 61 WRIPLGPLPHEFRGWIAPCRPRLGASEAGDWLRRPSEGALPGPYIALRSIPKLPPPEDIS 120 Query: 121 GILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKL 180 GILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKL Sbjct: 121 GILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKL 180 Query: 181 RPLLKKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQI 240 RPLLKKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQI Sbjct: 181 RPLLKKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQI 240 Query: 241 SHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAGPPCPGAPVCFHLGLGLPV 300 SHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAGPPCPGAPVCFHLGLGLPV Sbjct: 241 SHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAGPPCPGAPVCFHLGLGLPV 300 Query: 301 DIPHYTRLYSAGVAHSSAPATTLGLLRF 328 DIPHYTRLYSAGVAHSSAPATTLGLLRF Sbjct: 301 DIPHYTRLYSAGVAHSSAPATTLGLLRF 328 >gi|42560248 POU domain, class 5, transcription factor 1 isoform 1 [Homo sapiens] Length = 360 Score = 274 bits (700), Expect = 9e-74 Identities = 169/359 (47%), Positives = 207/359 (57%), Gaps = 40/359 (11%) Query: 1 MAGHRPSNH-FCPLPGSGGGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPD 59 MAGH S+ F P PG GG GP GP P VD TWLS Q PG P + PG+ PG + Sbjct: 1 MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGG----PGIGPGVGPGSE 56 Query: 60 VWRIPLGPLPHEFRGWIAPCRPRLGAS--------------EAGDWLRRPSEGALPGPYI 105 VW IP P P+EF G +A C P++G EAG + S+GA P P Sbjct: 57 VWGIPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCT 116 Query: 106 ALRSIPKLPPP---------EDISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFG 156 KL +DI + KEL+Q AK L+QKR++LGY+QADVG+ +G LFG Sbjct: 117 VTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFG 176 Query: 157 KVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVEA-ENLLGLCKMEMILQQSGKWRRA 215 KV SQTTICRFEA QLS NM KLRPLL+KW++E + ENL +CK E ++Q + K +R Sbjct: 177 KVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQ-ARKRKRT 235 Query: 216 SRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPR 275 S E R+ +LE F +CPKPT QQISHIA L L+KDVVRVWF NR + G R ++D + R Sbjct: 236 SIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQR 295 Query: 276 EIVGTAGPPCPGAPVCFHLG----LGLP-VDIPHYTRLYSA-----GVAHSSAPATTLG 324 E AG P G PV F L G P PH+T LYS+ G A TTLG Sbjct: 296 EDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLG 354 >gi|227430410 POU class 5 homeobox 1B [Homo sapiens] Length = 359 Score = 256 bits (654), Expect = 2e-68 Identities = 161/342 (47%), Positives = 196/342 (57%), Gaps = 38/342 (11%) Query: 1 MAGHRPSNH-FCPLPGSGGGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPD 59 MAGH S+ F P PG GG GP G P VD LTWLS Q PG P + PG+ PG + Sbjct: 1 MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGG----PGIGPGVGPGSE 56 Query: 60 VWRIPLGPLPHEFRGWIAPCRPRLGA--------------SEAGDWLRRPSEGALPGPYI 105 VW IP P P+E G +A C P++G SEAG + S GA P P Sbjct: 57 VWGIPPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCT 116 Query: 106 ALRSIPKLPPP---------EDISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFG 156 KL +DI + KEL+Q AK L+QKR++LGY+QADVG+ +G LFG Sbjct: 117 VPPGAVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFG 176 Query: 157 KVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVE-AENLLGLCKMEMILQQSGKWRRA 215 KV SQ TICRFEA QLS NM KLRPLL+KW++E + ENL +CK E L Q+ K +R Sbjct: 177 KVFSQKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAE-TLMQARKRKRT 235 Query: 216 SRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPR 275 S E R+ +LE F +CPKPT QISHIA L L+KDVVRVWF NR + G R ++D + R Sbjct: 236 SIENRVRGNLENLFLQCPKPT-LQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQR 294 Query: 276 EIVGTAGPPCPGAPVCF------HLGLGLPVDIPHYTRLYSA 311 E AG P G PV F H G PH+T LYS+ Sbjct: 295 EDFEAAGSPFSGGPVSFPPAPGPHFGTP-GYGSPHFTALYSS 335 >gi|116235491 POU domain, class 5, transcription factor 1 isoform 2 [Homo sapiens] Length = 265 Score = 204 bits (520), Expect = 7e-53 Identities = 118/232 (50%), Positives = 148/232 (63%), Gaps = 12/232 (5%) Query: 104 YIALRSIPKLPPPEDISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTT 163 Y+ +P +DI + KEL+Q AK L+QKR++LGY+QADVG+ +G LFGKV SQTT Sbjct: 29 YVLTSLLPFKIQSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTT 88 Query: 164 ICRFEAQQLSVANMWKLRPLLKKWLKEVEA-ENLLGLCKMEMILQQSGKWRRASRERRIG 222 ICRFEA QLS NM KLRPLL+KW++E + ENL +CK E ++Q + K +R S E R+ Sbjct: 89 ICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQ-ARKRKRTSIENRVR 147 Query: 223 NSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAG 282 +LE F +CPKPT QQISHIA L L+KDVVRVWF NR + G R ++D + RE AG Sbjct: 148 GNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAG 207 Query: 283 PPCPGAPVCFHLG----LGLP-VDIPHYTRLYSA-----GVAHSSAPATTLG 324 P G PV F L G P PH+T LYS+ G A TTLG Sbjct: 208 SPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLG 259 >gi|110624763 POU domain, class 3, transcription factor 4 [Homo sapiens] Length = 361 Score = 144 bits (362), Expect = 1e-34 Identities = 74/155 (47%), Positives = 100/155 (64%), Gaps = 2/155 (1%) Query: 125 ELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLL 184 EL+Q AK+ +Q+R+ LG++QADVG+A+G L+G V SQTTICRFE QLS NM KL+PLL Sbjct: 193 ELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEGLQLSFKNMCKLKPLL 252 Query: 185 KKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISHIA 244 KWL+E ++ ++ Q + +R S E + LE F +CPKP Q+IS +A Sbjct: 253 NKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLA 312 Query: 245 GCLQLQKDVVRVWFYNRSKMGSR--PTNDASPREI 277 LQL+K+VVRVWF NR + R P D P E+ Sbjct: 313 DSLQLEKEVVRVWFCNRRQKEKRMTPPGDQQPHEV 347 >gi|5453936 POU class 3 homeobox 3 [Homo sapiens] Length = 500 Score = 142 bits (359), Expect = 3e-34 Identities = 74/173 (42%), Positives = 107/173 (61%), Gaps = 4/173 (2%) Query: 125 ELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLL 184 +L+Q AK+ +Q+R+ LG++QADVG+A+G L+G V SQTTICRFEA QLS NM KL+PLL Sbjct: 321 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 380 Query: 185 KKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISHIA 244 KWL+E ++ ++ Q + +R S E + +LE F +CPKP+ Q+I+++A Sbjct: 381 NKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLA 440 Query: 245 GCLQLQKDVVRVWFYNRSKMGSRPT----NDASPREIVGTAGPPCPGAPVCFH 293 LQL+K+VVRVWF NR + R T +P ++ G P H Sbjct: 441 DSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSADTPPPHH 493 >gi|51702521 POU domain, class 3, transcription factor 2 [Homo sapiens] Length = 443 Score = 141 bits (356), Expect = 7e-34 Identities = 70/145 (48%), Positives = 100/145 (68%) Query: 125 ELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLL 184 +L+Q AK+ +Q+R+ LG++QADVG+A+G L+G V SQTTICRFEA QLS NM KL+PLL Sbjct: 269 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 328 Query: 185 KKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISHIA 244 KWL+E ++ + ++ Q + +R S E + +LE F +CPKP+ Q+I+ +A Sbjct: 329 NKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLA 388 Query: 245 GCLQLQKDVVRVWFYNRSKMGSRPT 269 LQL+K+VVRVWF NR + R T Sbjct: 389 DSLQLEKEVVRVWFCNRRQKEKRMT 413 >gi|110624765 POU domain, class 3, transcription factor 1 [Homo sapiens] Length = 451 Score = 139 bits (350), Expect = 3e-33 Identities = 75/167 (44%), Positives = 106/167 (63%), Gaps = 4/167 (2%) Query: 125 ELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLL 184 +L+Q AK+ +Q+R+ LG++QADVG+A+G L+G V SQTTICRFEA QLS NM KL+PLL Sbjct: 254 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 313 Query: 185 KKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISHIA 244 KWL+E ++ + ++ Q + +R S E + +LE F +CPKP+ +I+ +A Sbjct: 314 NKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLA 373 Query: 245 GCLQLQKDVVRVWFYNRSKMGSRPTNDAS----PREIVGTAGPPCPG 287 LQL+K+VVRVWF NR + R T A P + V G PG Sbjct: 374 DSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPG 420 >gi|148664218 POU transcription factor [Homo sapiens] Length = 436 Score = 122 bits (305), Expect = 6e-28 Identities = 86/228 (37%), Positives = 121/228 (53%), Gaps = 22/228 (9%) Query: 56 PGPDVWRIPLGPLPHEFRGWIAPCRPRLGASEAGDWLRRPSEGALPGPYIA--LRSIPKL 113 PG + L P P + G + P + G A P LPG + L + L Sbjct: 117 PGQQGLQPNLLPFPQQQSGLLLP---QTGPGLASQAFGHPG---LPGSSLEPHLEASQHL 170 Query: 114 PPPE--------DISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTIC 165 P P+ D L+EL++ AK +Q+R+ LG++Q DVG+A+G L+G SQTTI Sbjct: 171 PVPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTIS 230 Query: 166 RFEAQQLSVANMWKLRPLLKKWLKEVEAE----NLLGLCKMEMILQQSGKWR--RASRER 219 RFEA LS NM KL+PLL+KWL + E+ ++ + + G+ R R S E Sbjct: 231 RFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIET 290 Query: 220 RIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSR 267 I +LEK FQ PKP+ ++IS IA L ++K+VVRVWF NR + R Sbjct: 291 NIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKR 338 >gi|42476164 POU class 2 homeobox 1 [Homo sapiens] Length = 743 Score = 121 bits (304), Expect = 7e-28 Identities = 74/181 (40%), Positives = 101/181 (55%), Gaps = 15/181 (8%) Query: 111 PKLPPPEDISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQ 170 P L P D L+EL+Q AK +Q+R+ LG++Q DVG+A+G L+G SQTTI RFEA Sbjct: 277 PSLEEPSD----LEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEAL 332 Query: 171 QLSVANMWKLRPLLKKWLKEVEAENLLGLCKMEMILQQSG-------KWRRASRERRIGN 223 LS NM KL+PLL+KWL + E + L G + +R S E I Sbjct: 333 NLSFKNMCKLKPLLEKWLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRV 392 Query: 224 SLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAGP 283 +LEK F KPT ++I+ IA L ++K+V+RVWF NR + R +P GT+ Sbjct: 393 ALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKR----INPPSSGGTSSS 448 Query: 284 P 284 P Sbjct: 449 P 449 >gi|4505959 POU domain, class 2, transcription factor 2 [Homo sapiens] Length = 463 Score = 121 bits (303), Expect = 1e-27 Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 36/250 (14%) Query: 51 RPGICPGPDVWRIPLGPLPHEFRGWIAPCRPRLGA-SEAGDWLRRPSEGALPGPYIALRS 109 +PG+ P P++++ LP + +G + +PR G ++ L PS Sbjct: 135 QPGLLPTPNLFQ-----LPQQTQGALLTSQPRAGLPTQPPKCLEPPSH------------ 177 Query: 110 IPKLPPPEDISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEA 169 PE+ S L+EL+Q A+ +Q+R+ LG++Q DVG+A+G L+G SQTTI RFEA Sbjct: 178 ------PEEPSD-LEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEA 230 Query: 170 QQLSVANMWKLRPLLKKWLKEVEAENLLGLCKMEMILQQSG----------KWRRASRER 219 LS NM KL+PLL+KWL + E ++ L + +R S E Sbjct: 231 LNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIET 290 Query: 220 RIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVG 279 + +LEK F KPT ++I IA L ++K+V+RVWF NR + R N S ++ Sbjct: 291 NVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKR-INPCSAAPMLP 349 Query: 280 TAGPPCPGAP 289 + G P +P Sbjct: 350 SPGKPASYSP 359 >gi|170650730 pituitary specific transcription factor 1 isoform beta [Homo sapiens] Length = 317 Score = 105 bits (261), Expect = 7e-23 Identities = 59/145 (40%), Positives = 88/145 (60%), Gaps = 2/145 (1%) Query: 123 LKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRP 182 ++EL++ A E + +R+ LGY+Q +VG A+ A+ G SQTTICRFE QLS N KL+ Sbjct: 155 IRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKA 214 Query: 183 LLKKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISH 242 +L KWL+ EAE + L ++ + + RR + ++LE+ F KP+ Q+I Sbjct: 215 ILSKWLE--EAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMR 272 Query: 243 IAGCLQLQKDVVRVWFYNRSKMGSR 267 +A L L+K+VVRVWF NR + R Sbjct: 273 MAEELNLEKEVVRVWFCNRRQREKR 297 >gi|4505955 pituitary specific transcription factor 1 isoform alpha [Homo sapiens] Length = 291 Score = 105 bits (261), Expect = 7e-23 Identities = 59/145 (40%), Positives = 88/145 (60%), Gaps = 2/145 (1%) Query: 123 LKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRP 182 ++EL++ A E + +R+ LGY+Q +VG A+ A+ G SQTTICRFE QLS N KL+ Sbjct: 129 IRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKA 188 Query: 183 LLKKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISH 242 +L KWL+ EAE + L ++ + + RR + ++LE+ F KP+ Q+I Sbjct: 189 ILSKWLE--EAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMR 246 Query: 243 IAGCLQLQKDVVRVWFYNRSKMGSR 267 +A L L+K+VVRVWF NR + R Sbjct: 247 MAEELNLEKEVVRVWFCNRRQREKR 271 >gi|110347455 Brn3b POU domain transcription factor [Homo sapiens] Length = 409 Score = 99.8 bits (247), Expect = 3e-21 Identities = 61/155 (39%), Positives = 91/155 (58%), Gaps = 7/155 (4%) Query: 118 DISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKV-----LSQTTICRFEAQQL 172 D+ ++L+ A+ +Q+R+ LG +QADVG A+ L K+ LSQ+TICRFE+ L Sbjct: 250 DVDADPRDLEAFAERFKQRRIKLGVTQADVGSALANL--KIPGVGSLSQSTICRFESLTL 307 Query: 173 SVANMWKLRPLLKKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRC 232 S NM L+P+L+ WL+E E + L K E+ K +R S SLE +F Sbjct: 308 SHNNMIALKPILQAWLEEAEKSHREKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFAIQ 367 Query: 233 PKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSR 267 P+P+ ++I+ IA L L+K+VVRVWF N+ + R Sbjct: 368 PRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 402 >gi|110347449 POU domain, class 4, transcription factor 1 [Homo sapiens] Length = 419 Score = 99.4 bits (246), Expect = 4e-21 Identities = 88/273 (32%), Positives = 126/273 (46%), Gaps = 50/273 (18%) Query: 14 PGSGGGGPRG--------PMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPDVWRIPL 65 PG GGGGP G P P + +L LS AA + +P Sbjct: 171 PGGGGGGPGGGLLGGSAHPHP-HMHSLGHLSHPAAAAAM-----------------NMPS 212 Query: 66 GPLPHEFRGWIAPCRPRLGASEAGDWLRRPSEGALPGPYIALRSIPKLPPPEDISGIL-- 123 G LPH P L A+ A + A G A + + ++ I Sbjct: 213 G-LPH----------PGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDS 261 Query: 124 ----KELQQLAKELRQKRLSLGYSQADVGIAVGALFGKV-----LSQTTICRFEAQQLSV 174 +EL+ A+ +Q+R+ LG +QADVG A+ L K+ LSQ+TICRFE+ LS Sbjct: 262 DTDPRELEAFAERFKQRRIKLGVTQADVGSALANL--KIPGVGSLSQSTICRFESLTLSH 319 Query: 175 ANMWKLRPLLKKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPK 234 NM L+P+L+ WL+E E + K E+ K +R S SLE +F P+ Sbjct: 320 NNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPR 379 Query: 235 PTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSR 267 P+ ++I+ IA L L+K+VVRVWF N+ + R Sbjct: 380 PSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 412 >gi|4505965 POU class 4 homeobox 3 [Homo sapiens] Length = 338 Score = 99.0 bits (245), Expect = 5e-21 Identities = 62/155 (40%), Positives = 90/155 (58%), Gaps = 7/155 (4%) Query: 118 DISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKV-----LSQTTICRFEAQQL 172 D+ +EL+ A+ +Q+R+ LG +QADVG A+ L K+ LSQ+TICRFE+ L Sbjct: 179 DVESDPRELEAFAERFKQRRIKLGVTQADVGAALANL--KIPGVGSLSQSTICRFESLTL 236 Query: 173 SVANMWKLRPLLKKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRC 232 S NM L+P+L+ WL+E EA K E+ K +R S SLE +F Sbjct: 237 SHNNMIALKPVLQAWLEEAEAAYREKNSKPELFNGSERKRKRTSIAAPEKRSLEAYFAIQ 296 Query: 233 PKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSR 267 P+P+ ++I+ IA L L+K+VVRVWF N+ + R Sbjct: 297 PRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 331 >gi|223890225 POU class 6 homeobox 1 [Homo sapiens] Length = 301 Score = 98.6 bits (244), Expect = 7e-21 Identities = 81/257 (31%), Positives = 121/257 (47%), Gaps = 19/257 (7%) Query: 21 PRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPDVWRIPLGPLPHEFRGWIAPCR 80 P L+V +T A G+V+ A P P P R P P + + P + Sbjct: 32 PAPAQSLQVQAVTPQLLLNAQGQVIATLASSP--LPPPVAVRKPSTP-ESPAKSEVQPIQ 88 Query: 81 PRLGASEAGDWLRRPSEGALPG------------PYIA-LRSIPKLPPPEDISGILKELQ 127 P + + P+ A P P ++ L S P P ++ L+E++ Sbjct: 89 PTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIR 148 Query: 128 QLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLLKKW 187 + AK + +RLSLG +Q VG A+ A G SQ+ ICRFE ++ + KL+P+L+KW Sbjct: 149 EFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVLEKW 208 Query: 188 LKEVEAENLLGLCK-MEMILQQSGK--WRRASRERRIGNSLEKFFQRCPKPTPQQISHIA 244 L E E N G ME + + K RR S + +L +F++ P PT Q+I+ IA Sbjct: 209 LNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIA 268 Query: 245 GCLQLQKDVVRVWFYNR 261 L ++VVRVWF NR Sbjct: 269 KELNYDREVVRVWFCNR 285 >gi|157743257 POU domain, class 6, transcription factor 2 [Homo sapiens] Length = 691 Score = 70.5 bits (171), Expect = 2e-12 Identities = 50/184 (27%), Positives = 87/184 (47%), Gaps = 40/184 (21%) Query: 118 DISGI-LKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRF--------- 167 ++ G+ L+E+++ AK + +RLSLG +Q VG A+ A G SQ+ ICR Sbjct: 475 EVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFL 534 Query: 168 --EAQQLSVA-------------------------NMWKLRPLLKKWLKEVEAENLLGLC 200 EAQ+ ++A + K++P+L++W+ E EA + G+ Sbjct: 535 PQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQ 594 Query: 201 KMEMILQQSGKWRRASRERRIGNSLE---KFFQRCPKPTPQQISHIAGCLQLQKDVVRVW 257 + + +R R +LE F++ P+ Q+++ IA L ++VVRVW Sbjct: 595 NLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVW 654 Query: 258 FYNR 261 F N+ Sbjct: 655 FCNK 658 >gi|113416879 PREDICTED: hypothetical protein [Homo sapiens] Length = 175 Score = 36.2 bits (82), Expect = 0.041 Identities = 40/111 (36%), Positives = 45/111 (40%), Gaps = 18/111 (16%) Query: 11 CPLPGSGG-GGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGIC----PGPDVWRIPL 65 CP P +GG GP P R + A P R VW PG PG D R+P Sbjct: 73 CPSPAAGGLRGPWTAAPGR-QRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPP 131 Query: 66 GPLPHEFRGWIAPCRPRL-GASEAGDWLRRPSEGALPGPYIALRSIPKLPP 115 P P P RPRL A AG P++ A P P A RS P P Sbjct: 132 PPPP-------PPERPRLPPAGLAGG----PADSAPPSPAPAPRSRPAPRP 171 >gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens] Length = 334 Score = 34.7 bits (78), Expect = 0.12 Identities = 32/115 (27%), Positives = 44/115 (38%), Gaps = 19/115 (16%) Query: 225 LEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYN-RSKMGSRPTNDASPREIVGTAGP 283 LE FQRC ++ + +A L L + V+VWF N R+K D+ R +V Sbjct: 115 LEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAA 174 Query: 284 PC--------------PGAPV----CFHLGLGLPVDIPHYTRLYSAGVAHSSAPA 320 C PG P C LG + P L + A S+A A Sbjct: 175 TCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAA 229 >gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo sapiens] Length = 382 Score = 34.3 bits (77), Expect = 0.16 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 7/76 (9%) Query: 193 AENLLGLCKMEMILQ-QSGKWRRASRERRIG------NSLEKFFQRCPKPTPQQISHIAG 245 AE L G ++IL+ + G R R R +LEK FQ+ P +A Sbjct: 47 AERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAM 106 Query: 246 CLQLQKDVVRVWFYNR 261 C L + V+VWF NR Sbjct: 107 CTNLPEARVQVWFKNR 122 >gi|154355000 KH-type splicing regulatory protein [Homo sapiens] Length = 711 Score = 33.5 bits (75), Expect = 0.27 Identities = 45/154 (29%), Positives = 57/154 (37%), Gaps = 49/154 (31%) Query: 11 CPL-PGSGGGGPRGPM-PLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPDVWRIPLGPL 68 CP+ PG GG GP GPM P PG P PG P GP Sbjct: 500 CPVGPGPGGPGPAGPMGPFN------------PGPFNQGP---PGAPPHAG------GPP 538 Query: 69 PHEF--RGW---------IAPCRPRLGASEAGD----WLRRPSE------GALPGPYIA- 106 PH++ +GW AP P A+ A D W S G +PGP A Sbjct: 539 PHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAP 598 Query: 107 ----LRSIPKLPPPEDISGILKELQQLAKELRQK 136 + P PPP S K ++ K++ Q+ Sbjct: 599 AAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQ 632 >gi|210147470 NK2 transcription factor related, locus 6 [Homo sapiens] Length = 219 Score = 33.5 bits (75), Expect = 0.27 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 17/83 (20%) Query: 224 SLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDAS---------P 274 +LE+ F++ + + H+A LQL V++WF NR R D S P Sbjct: 64 ALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTP 123 Query: 275 REIVGTA----GPPC----PGAP 289 R + G PC PGAP Sbjct: 124 RRVAVPVLVRDGKPCLGPGPGAP 146 >gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens] Length = 324 Score = 33.1 bits (74), Expect = 0.35 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 6/94 (6%) Query: 225 LEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAGPP 284 LE+ F++ + + +A L+L V++WF NR R D + E+VG PP Sbjct: 153 LERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQT-LELVGLPPPP 211 Query: 285 CPGA-----PVCFHLGLGLPVDIPHYTRLYSAGV 313 P A PV G D Y Y G+ Sbjct: 212 PPPARRIAVPVLVRDGKPCLGDSAPYAPAYGVGL 245 >gi|157426823 NK2 homeobox 4 [Homo sapiens] Length = 354 Score = 32.7 bits (73), Expect = 0.45 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 2/67 (2%) Query: 225 LEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREI--VGTAG 282 LE+ F++ + + H+A + L V++WF N R D + +++ G G Sbjct: 204 LERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLG 263 Query: 283 PPCPGAP 289 PP P P Sbjct: 264 PPPPPPP 270 >gi|4758168 distal-less homeobox 2 [Homo sapiens] Length = 328 Score = 32.3 bits (72), Expect = 0.59 Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 16/94 (17%) Query: 209 SGKWRRASRERRIGNS-----LEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRS- 262 +GK ++ + R I +S L++ FQ+ + + +A L L + V++WF NR Sbjct: 146 NGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRS 205 Query: 263 ------KMGSRPTNDASPREIVGTAGPPCPGAPV 290 K G P S + +A PPC PV Sbjct: 206 KFKKMWKSGEIP----SEQHPGASASPPCASPPV 235 >gi|170784824 paired box 4 [Homo sapiens] Length = 343 Score = 32.3 bits (72), Expect = 0.59 Identities = 17/38 (44%), Positives = 20/38 (52%) Query: 224 SLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNR 261 +LEK FQR P +A L +D VRVWF NR Sbjct: 176 ALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNR 213 >gi|4885363 goosecoid homeobox 2 [Homo sapiens] Length = 205 Score = 32.3 bits (72), Expect = 0.59 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 6/81 (7%) Query: 210 GKWRRASRERRIGN-----SLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYN-RSK 263 G RR R R I + +LE F + P +AG ++L+++ V VWF N R+K Sbjct: 121 GSQRRTRRHRTIFSEEQLQALEALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNRRAK 180 Query: 264 MGSRPTNDASPREIVGTAGPP 284 + AS R + G P Sbjct: 181 WRHQKRASASARLLPGVKKSP 201 >gi|4504465 homeobox B2 [Homo sapiens] Length = 356 Score = 32.3 bits (72), Expect = 0.59 Identities = 18/46 (39%), Positives = 21/46 (45%), Gaps = 4/46 (8%) Query: 243 IAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAGPPCPGA 288 IA L L + V+VWF NR R T P + P CPGA Sbjct: 176 IAALLDLTERQVKVWFQNRRMKHKRQTQHREPPD----GEPACPGA 217 >gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] Length = 292 Score = 32.0 bits (71), Expect = 0.77 Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 3/96 (3%) Query: 223 NSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAG 282 N LE+ F P ++ L L + V+VWF NR + N I+GTA Sbjct: 130 NELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTAN 189 Query: 283 --PPCPGAPVCFHLGLGLPVDIPHYTRLYSAGVAHS 316 C AP L +P +L GVAH+ Sbjct: 190 HLDACRVAPYVNMGALRMPFQ-QVQAQLQLEGVAHA 224 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.140 0.457 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,365,660 Number of Sequences: 37866 Number of extensions: 930839 Number of successful extensions: 3330 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 46 Number of HSP's successfully gapped in prelim test: 64 Number of HSP's that attempted gapping in prelim test: 3213 Number of HSP's gapped (non-prelim): 159 length of query: 328 length of database: 18,247,518 effective HSP length: 103 effective length of query: 225 effective length of database: 14,347,320 effective search space: 3228147000 effective search space used: 3228147000 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.