Guide to the Human Genome
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Search of human proteins with 23111038

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23111038 sorting nexin 2 [Homo sapiens]
         (519 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23111038 sorting nexin 2 [Homo sapiens]                           1013   0.0  
gi|23111034 sorting nexin 1 isoform a [Homo sapiens]                  593   e-170
gi|23111032 sorting nexin 1 isoform b [Homo sapiens]                  537   e-153
gi|23111036 sorting nexin 1 isoform c [Homo sapiens]                  501   e-142
gi|23111047 sorting nexin 5 [Homo sapiens]                            107   3e-23
gi|7657599 sorting nexin 5 [Homo sapiens]                             107   3e-23
gi|194294540 sorting nexin 7 isoform a [Homo sapiens]                 106   6e-23
gi|153791707 sorting nexin family member 30 [Homo sapiens]            100   3e-21
gi|72534838 sorting nexin 6B [Homo sapiens]                           100   3e-21
gi|23111055 sorting nexin 7 isoform b [Homo sapiens]                   93   5e-19
gi|88703041 sorting nexin 6 isoform b [Homo sapiens]                   86   8e-17
gi|4507143 sorting nexin 3 isoform a [Homo sapiens]                    72   2e-12
gi|4507145 sorting nexin 4 [Homo sapiens]                              69   8e-12
gi|23111030 sorting nexin 12 [Homo sapiens]                            67   4e-11
gi|23943858 sorting nexin 8 [Homo sapiens]                             61   2e-09
gi|7706706 sorting nexin 9 [Homo sapiens]                              59   1e-08
gi|23111026 sorting nexin 11 [Homo sapiens]                            57   5e-08
gi|23111028 sorting nexin 11 [Homo sapiens]                            57   5e-08
gi|23397574 sorting nexin 33 [Homo sapiens]                            54   5e-07
gi|88703043 sorting nexin 6 isoform a [Homo sapiens]                   50   7e-06
gi|23111023 sorting nexin 10 [Homo sapiens]                            49   8e-06
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   49   8e-06
gi|157057545 sorting nexin 18 isoform a [Homo sapiens]                 49   1e-05
gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [H...    49   1e-05
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H...    49   1e-05
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H...    49   1e-05
gi|68800430 HCLS1 binding protein 3 [Homo sapiens]                     48   2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens]                           47   3e-05
gi|157502171 sorting nexin 19 [Homo sapiens]                           46   7e-05
gi|154091028 sorting nexin 29 [Homo sapiens]                           45   2e-04

>gi|23111038 sorting nexin 2 [Homo sapiens]
          Length = 519

 Score = 1013 bits (2620), Expect = 0.0
 Identities = 519/519 (100%), Positives = 519/519 (100%)

Query: 1   MAAEREPPPLGDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAEDISANSNGPK 60
           MAAEREPPPLGDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAEDISANSNGPK
Sbjct: 1   MAAEREPPPLGDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAEDISANSNGPK 60

Query: 61  PTEVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSA 120
           PTEVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSA
Sbjct: 61  PTEVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSA 120

Query: 121 PVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSV 180
           PVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSV
Sbjct: 121 PVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSV 180

Query: 181 KRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALE 240
           KRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALE
Sbjct: 181 KRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALE 240

Query: 241 RYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMN 300
           RYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMN
Sbjct: 241 RYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMN 300

Query: 301 ESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTAL 360
           ESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTAL
Sbjct: 301 ESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTAL 360

Query: 361 SRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDA 420
           SRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDA
Sbjct: 361 SRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDA 420

Query: 421 QITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEK 480
           QITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEK
Sbjct: 421 QITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEK 480

Query: 481 ERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519
           ERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA
Sbjct: 481 ERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519


>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
          Length = 522

 Score =  593 bits (1530), Expect = e-170
 Identities = 318/532 (59%), Positives = 390/532 (73%), Gaps = 33/532 (6%)

Query: 2   AAEREPPPL-----------GDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAE 50
           A+ER PPP            G  +P   +   +GED+FT      +        + LP  
Sbjct: 10  ASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSPKITTSLLPI- 68

Query: 51  DISANSNGPKPTEVVLDDDRE--DLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTL 108
                +NG K   +  + D+E  DLFA+AT E+SLDS +               V   TL
Sbjct: 69  -----NNGSKENGIHEEQDQEPQDLFADATVELSLDSTQNNQ----------KKVLAKTL 113

Query: 109 IA-PRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTK 167
           I+ P  E+ + S P     + EE+EEE   D FD+ +G++DPEK+GDGMNAY+AY+VTT+
Sbjct: 114 ISLPPQEATNSSKP---QPTYEELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQ 170

Query: 168 TSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSS 227
           TSL +F   +F+VKRRFSDFLGL+ KL+ K+   G+IVPP PEKS++GMTKVKVGKEDSS
Sbjct: 171 TSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSS 230

Query: 228 STEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNK 287
           S EF+EKRRAALERYLQR V HPT+LQDPD+R+FLE  ELPRAV TQ LSGAG+L+M NK
Sbjct: 231 SAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNK 290

Query: 288 AADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKS 347
           A DAV+KMTIKMNESD WFEEK Q+ E  +Q+LRKLH  VE LV HRKEL+ NTA FAKS
Sbjct: 291 ATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKS 350

Query: 348 AAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVF 407
            AMLG+SED+TALSRALSQLAEVEEKI+QLHQEQA  DF++ +ELLSDYIRL+A V+  F
Sbjct: 351 LAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAF 410

Query: 408 DHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQI 467
           D RMK WQ+W+DAQ TL KKREAEA+++ ANKPDK+QQAK+EI EWE++V Q ERDFE+I
Sbjct: 411 DQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERI 470

Query: 468 SKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519
           S  +RKEV RFEKE+ KDFK  +IKYLE+L+ +QQQL KYWEAFLPEAKAI+
Sbjct: 471 STVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS 522


>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
          Length = 457

 Score =  537 bits (1384), Expect = e-153
 Identities = 287/478 (60%), Positives = 352/478 (73%), Gaps = 37/478 (7%)

Query: 42  PEPASLPAEDISANSNGPKPTEVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVT 101
           P P   P  + +A  + P+  +   D + ED+F  A             ++S   SP +T
Sbjct: 17  PFPGLEPESEGAAGGSEPEAGDS--DTEGEDIFTGAA------------VVSKHQSPKIT 62

Query: 102 PVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMA 161
               T+L+     SK        +    E +++   D+F            GDGMNAY+A
Sbjct: 63  ----TSLLPINNGSK--------ENGIHEEQDQEPQDLF-----------AGDGMNAYVA 99

Query: 162 YRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKV 221
           Y+VTT+TSL +F   +F+VKRRFSDFLGL+ KL+ K+   G+IVPP PEKS++GMTKVKV
Sbjct: 100 YKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKV 159

Query: 222 GKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGI 281
           GKEDSSS EF+EKRRAALERYLQR V HPT+LQDPD+R+FLE  ELPRAV TQ LSGAG+
Sbjct: 160 GKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGL 219

Query: 282 LRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANT 341
           L+M NKA DAV+KMTIKMNESD WFEEK Q+ E  +Q+LRKLH  VE LV HRKEL+ NT
Sbjct: 220 LKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNT 279

Query: 342 AAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIA 401
           A FAKS AMLG+SED+TALSRALSQLAEVEEKI+QLHQEQA  DF++ +ELLSDYIRL+A
Sbjct: 280 AQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLA 339

Query: 402 AVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGE 461
            V+  FD RMK WQ+W+DAQ TL KKREAEA+++ ANKPDK+QQAK+EI EWE++V Q E
Sbjct: 340 IVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYE 399

Query: 462 RDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519
           RDFE+IS  +RKEV RFEKE+ KDFK  +IKYLE+L+ +QQQL KYWEAFLPEAKAI+
Sbjct: 400 RDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS 457


>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
          Length = 474

 Score =  501 bits (1290), Expect = e-142
 Identities = 285/532 (53%), Positives = 350/532 (65%), Gaps = 81/532 (15%)

Query: 2   AAEREPPPL-----------GDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAE 50
           A+ER PPP            G  +P   +   +GED+FT      +        + LP  
Sbjct: 10  ASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSPKITTSLLPI- 68

Query: 51  DISANSNGPKPTEVVLDDDRE--DLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTL 108
                +NG K   +  + D+E  DLFA+AT E+SLDS +               V   TL
Sbjct: 69  -----NNGSKENGIHEEQDQEPQDLFADATVELSLDSTQNNQ----------KKVLAKTL 113

Query: 109 IA-PRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTK 167
           I+ P  E+ + S P     + EE+EEE   D FD+ +G++DPEK+GDGMNAY+AY+VTT+
Sbjct: 114 ISLPPQEATNSSKP---QPTYEELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQ 170

Query: 168 TSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSS 227
           TSL +F   +F+VKRRFSDFLGL+ KL+ K+   G+IVPP PEKS++GMTKVKVGKEDSS
Sbjct: 171 TSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSS 230

Query: 228 STEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNK 287
           S EF+EKRRAALERYLQR V HPT+LQDPD+R+FLE  ELPRAV TQ LSGAG+L+M NK
Sbjct: 231 SAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNK 290

Query: 288 AADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKS 347
           A DAV+KMTIKMNESD WFEEK Q+ E  +Q+LRKLH  VE LV HRKEL+ NTA FAKS
Sbjct: 291 ATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKS 350

Query: 348 AAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVF 407
            AMLG+SED+TALSRALSQLAEVEEKI+QLHQEQA  DF++ +ELLSDYIRL+A V+   
Sbjct: 351 LAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVR--- 407

Query: 408 DHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQI 467
                                                        WE++V Q ERDFE+I
Sbjct: 408 ---------------------------------------------WESRVTQYERDFERI 422

Query: 468 SKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519
           S  +RKEV RFEKE+ KDFK  +IKYLE+L+ +QQQL KYWEAFLPEAKAI+
Sbjct: 423 STVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS 474


>gi|23111047 sorting nexin 5 [Homo sapiens]
          Length = 404

 Score =  107 bits (266), Expect = 3e-23
 Identities = 101/379 (26%), Positives = 175/379 (46%), Gaps = 55/379 (14%)

Query: 141 DIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLH 200
           DI   +S+ +KV         + V TKT+L  F   EFSV R+  DF+ LH  L     +
Sbjct: 34  DIPDALSERDKV--------KFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDY 85

Query: 201 VGYIVPPAPEKSIVG-----MTKVKVGKEDSSSTEFVEKRR--------------AALER 241
            G I+PPAP K         M K+  G+   +  EF + ++              ++ E 
Sbjct: 86  AGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEV 145

Query: 242 YLQRTVKHPTLLQDPDLRQFLESSE--LPRAVNTQALSGAGILRMVNKAADAVNKMTIKM 299
           +LQR   HP L +D +   FLE  +    R  NT+ + G G  + V K+AD V    +K 
Sbjct: 146 FLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFG-GFFKSVVKSADEVLFTGVK- 203

Query: 300 NESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELS---ANTAAFAKSAAMLGNSED 356
            E D +FE+++    N   +++   V  + +    K ++    +TAA   S A+    E+
Sbjct: 204 -EVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLAL----EE 258

Query: 357 HTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQK 416
            T + + L ++AE+ EK+ ++    +  +    +ELL  Y+  I A K +   R K    
Sbjct: 259 PTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALID 318

Query: 417 WEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVG 476
           +E++   L                DK +    +++  EA  Q+  + FEQ+S++ ++E+ 
Sbjct: 319 YENSNKAL----------------DKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELI 362

Query: 477 RFEKERVKDFKTVIIKYLE 495
            F+++RV  F+  +I+  E
Sbjct: 363 NFKRKRVAAFRKNLIEMSE 381


>gi|7657599 sorting nexin 5 [Homo sapiens]
          Length = 404

 Score =  107 bits (266), Expect = 3e-23
 Identities = 101/379 (26%), Positives = 175/379 (46%), Gaps = 55/379 (14%)

Query: 141 DIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLH 200
           DI   +S+ +KV         + V TKT+L  F   EFSV R+  DF+ LH  L     +
Sbjct: 34  DIPDALSERDKV--------KFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDY 85

Query: 201 VGYIVPPAPEKSIVG-----MTKVKVGKEDSSSTEFVEKRR--------------AALER 241
            G I+PPAP K         M K+  G+   +  EF + ++              ++ E 
Sbjct: 86  AGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEV 145

Query: 242 YLQRTVKHPTLLQDPDLRQFLESSE--LPRAVNTQALSGAGILRMVNKAADAVNKMTIKM 299
           +LQR   HP L +D +   FLE  +    R  NT+ + G G  + V K+AD V    +K 
Sbjct: 146 FLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFG-GFFKSVVKSADEVLFTGVK- 203

Query: 300 NESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELS---ANTAAFAKSAAMLGNSED 356
            E D +FE+++    N   +++   V  + +    K ++    +TAA   S A+    E+
Sbjct: 204 -EVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLAL----EE 258

Query: 357 HTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQK 416
            T + + L ++AE+ EK+ ++    +  +    +ELL  Y+  I A K +   R K    
Sbjct: 259 PTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALID 318

Query: 417 WEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVG 476
           +E++   L                DK +    +++  EA  Q+  + FEQ+S++ ++E+ 
Sbjct: 319 YENSNKAL----------------DKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELI 362

Query: 477 RFEKERVKDFKTVIIKYLE 495
            F+++RV  F+  +I+  E
Sbjct: 363 NFKRKRVAAFRKNLIEMSE 381


>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
          Length = 451

 Score =  106 bits (264), Expect = 6e-23
 Identities = 104/465 (22%), Positives = 190/465 (40%), Gaps = 68/465 (14%)

Query: 53  SANSNGPKPTEVV-LDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAP 111
           S+ S+     EV+ LD+D +DL   + +   +D     P++         P +P ++I  
Sbjct: 34  SSGSSALLQAEVLDLDEDEDDLEVFSKDASLMDMNSFSPMM---------PTSPLSMI-- 82

Query: 112 RIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLS 171
                             +I+ E   D+ D+ I V +PE     +  ++ YR+ TKTS  
Sbjct: 83  -----------------NQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSRG 125

Query: 172 MFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEF 231
            F  SEF V+RR+ DFL L  KL  +  H   I+PP PEK IV       G  +  + +F
Sbjct: 126 EFDSSEFEVRRRYQDFLWLKGKL--EEAHPTLIIPPLPEKFIV------KGMVERFNDDF 177

Query: 232 VEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADA 291
           +E RR AL ++L R   HPTL  + D + FL +      +++    G G+L  + +   A
Sbjct: 178 IETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAW--ELSSHKKQGPGLLSRMGQTVRA 235

Query: 292 VNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAML 351
           V      +      F E     E   Q++  +    + +    +E       +     + 
Sbjct: 236 VASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILW 295

Query: 352 GNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRM 411
             SE+   L   L  +A   ++  +  +++          ++ +Y+     + GV   R 
Sbjct: 296 SASEED--LVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRD 353

Query: 412 KCWQKWEDAQITLLKKREAEAKMM---VANKPDKIQQAKNEIR-EWEAKVQQGERDFEQI 467
           +  Q   D+++ +L  ++A+  ++   +    DK++ A N ++ +WE             
Sbjct: 354 QI-QAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWE------------- 399

Query: 468 SKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFL 512
                    R+++    D K       E  +   +Q +  WE+FL
Sbjct: 400 ---------RWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFL 435


>gi|153791707 sorting nexin family member 30 [Homo sapiens]
          Length = 437

 Score =  100 bits (249), Expect = 3e-21
 Identities = 95/398 (23%), Positives = 183/398 (45%), Gaps = 56/398 (14%)

Query: 127 SREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSD 186
           +R +++++ +G+  D+ + V DP+K    M  Y+ YR+TTK++   F   E+SV+RR+ D
Sbjct: 76  NRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQD 135

Query: 187 FLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRT 246
           F  L SKL        +++PP PEK +V       G  D  S EFVE RR AL+++L+R 
Sbjct: 136 FDWLRSKLEES--QPTHLIPPLPEKFVV------KGVVDRFSEEFVETRRKALDKFLKRI 187

Query: 247 VKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVN---KMTIKMNESD 303
             HP L  +     FL + +L    N     G  +L  + ++   V    K+  +  E  
Sbjct: 188 TDHPVLSFNEHFNIFLTAKDL----NAYKKQGIALLTRMGESVKHVTGGYKLRTRPLEFA 243

Query: 304 A------WFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGN-SED 356
           A       F  K    + + Q++ K    +E LV    EL      ++  +A+ G  +E 
Sbjct: 244 AIGDYLDTFALKLGTIDRIAQRIIK--EEIEYLV----ELREYGPVYSTWSALEGELAEP 297

Query: 357 HTALSRALSQLA-EVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQ 415
              +S  +   +  +EE  D + ++        F  +L +YI                  
Sbjct: 298 LEGVSACIGNCSTALEELTDDMTED--------FLPVLREYI------------------ 331

Query: 416 KWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEV 475
            + D+  ++LKKR+ + +     K + +   K +  +  A V++ +   E  +  ++ ++
Sbjct: 332 LYSDSMKSVLKKRD-QVQAEYEAKLEAVALRKEDRPKVPADVEKCQDRMECFNADLKADM 390

Query: 476 GRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLP 513
            R++  + +DF+ +++   +  +Q  ++ +  WE+ +P
Sbjct: 391 ERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESIIP 428


>gi|72534838 sorting nexin 6B [Homo sapiens]
          Length = 403

 Score =  100 bits (249), Expect = 3e-21
 Identities = 95/376 (25%), Positives = 170/376 (45%), Gaps = 46/376 (12%)

Query: 141 DIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLH 200
           +I   VS+ +KV         + V TK+ L  F+++EFSV R+  +F+ LH        +
Sbjct: 29  EISDAVSERDKV--------KFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEY 80

Query: 201 VGYIVPPAPEKSIVGMTK---VKVGKEDSSST--EFVEKRR--------------AALER 241
            G I+PPAP +     ++    K+G+ DSS T  EF + ++              A  E 
Sbjct: 81  AGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEV 140

Query: 242 YLQRTVKHPTLLQDPDLRQFLESSE--LPRAVNTQALSGAGILRMVNKAADAVNKMTIKM 299
           +LQR   HPTL +D +   FLE  +    R  N + L G  +  +V  A +A+      +
Sbjct: 141 FLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITGMSGL 200

Query: 300 NESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTA 359
            E D +FE ++        ++R   +  + ++   K L+ +    + + + LG  E +  
Sbjct: 201 KEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQEVN-Q 259

Query: 360 LSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWED 419
           L  +  +LAE+ E++ +L    A  +    S++L  Y+R   A K +   R++    +E+
Sbjct: 260 LRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYEN 319

Query: 420 AQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFE 479
           A   L                DK +    E+R  E+  Q   + FE++S + ++E+  F+
Sbjct: 320 ANKAL----------------DKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFK 363

Query: 480 KERVKDFKTVIIKYLE 495
             RV  F+  +I+  E
Sbjct: 364 SRRVSSFRKNLIELAE 379


>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
          Length = 336

 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 76/308 (24%), Positives = 136/308 (44%), Gaps = 13/308 (4%)

Query: 130 EIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLG 189
           +I+ E   D+ D+ I V +PE     +  ++ YR+ TKTS   F  SEF V+RR+ DFL 
Sbjct: 20  QIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLW 79

Query: 190 LHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKH 249
           L  KL  +  H   I+PP PEK IV       G  +  + +F+E RR AL ++L R   H
Sbjct: 80  LKGKL--EEAHPTLIIPPLPEKFIV------KGMVERFNDDFIETRRKALHKFLNRIADH 131

Query: 250 PTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEK 309
           PTL  + D + FL +      +++    G G+L  + +   AV      +      F E 
Sbjct: 132 PTLTFNEDFKIFLTAQAW--ELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEM 189

Query: 310 QQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAE 369
               E   Q++  +    + +    +E       +     +   SE+   L   L  +A 
Sbjct: 190 NNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEED--LVDTLKDVAS 247

Query: 370 VEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKRE 429
             ++  +  +++          ++ +Y+     + GV   R +  Q   D+++ +L  ++
Sbjct: 248 CIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQI-QAELDSKVEVLTYKK 306

Query: 430 AEAKMMVA 437
           A+  + +A
Sbjct: 307 ADTDLCLA 314


>gi|88703041 sorting nexin 6 isoform b [Homo sapiens]
          Length = 418

 Score = 85.9 bits (211), Expect = 8e-17
 Identities = 89/394 (22%), Positives = 165/394 (41%), Gaps = 50/394 (12%)

Query: 125 DRSREEIEEEANGDI---FDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVK 181
           DR  + I  +   D     DI   +S+ +KV         + V TK+SL  F ++EFSV 
Sbjct: 28  DRGLKAINVDLQSDAALQVDISDALSERDKV--------KFTVHTKSSLPNFKQNEFSVV 79

Query: 182 RRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGK----EDSSSTEFVEKRRA 237
           R+  +F+ LH        + GYI+PPAP +     ++ K+ K    E S + E   K + 
Sbjct: 80  RQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQ 139

Query: 238 ALER---------------YLQRTVKHPTLLQDPDLRQFLE-SSELPRAVNTQALSGAGI 281
            LE                +L R   HP L +D +   FLE + +L      +       
Sbjct: 140 ELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDF 199

Query: 282 LRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANT 341
            + + K+AD V    +K  + D +FE ++        +++      + +    K  + + 
Sbjct: 200 FKNMVKSADGVIVSGVK--DVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDY 257

Query: 342 AAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIA 401
                S   LG ++D T + +   +++E+ +K  ++    +  +    S+LL  Y+R   
Sbjct: 258 NRIGSSLYALG-TQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQ 316

Query: 402 AVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGE 461
           A K +   R +    +E+A   L                DK +    ++ + E   Q   
Sbjct: 317 AAKDLLYRRSRSLVDYENANKAL----------------DKARAKNKDVLQAETSQQLCC 360

Query: 462 RDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLE 495
           + FE+IS++ ++E+  F+  RV  F+  +++  E
Sbjct: 361 QKFEKISESAKQELIDFKTRRVAAFRKNLVELAE 394


>gi|4507143 sorting nexin 3 isoform a [Homo sapiens]
          Length = 162

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 39/129 (30%), Positives = 68/129 (52%), Gaps = 4/129 (3%)

Query: 142 IEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHV 201
           +EI VS+P+ VG G   +  Y +  KT+L +F   E +V+RR+SDF  L S+L  +    
Sbjct: 29  LEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERE---S 85

Query: 202 GYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQF 261
             +VPP P K+ +     + G +      F+E+R+  LE+++ +   HP    +  L  F
Sbjct: 86  KVVVPPLPGKAFLRQLPFR-GDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMF 144

Query: 262 LESSELPRA 270
           L+   + ++
Sbjct: 145 LQDEIIDKS 153


>gi|4507145 sorting nexin 4 [Homo sapiens]
          Length = 450

 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 95/410 (23%), Positives = 163/410 (39%), Gaps = 70/410 (17%)

Query: 142 IEIGVSDPEKVGDGMNA------YMAYRVTTKTSLSMFSKSEF--SVKRRFSDFLGLHSK 193
           IEI VS+ EK   G NA      Y AY + T++      +S    S+ RR+S+F  L S 
Sbjct: 58  IEISVSEAEK-RTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSY 116

Query: 194 LASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLL 253
           L   Y H+  +VPP PEK    +        D+   +FVE+RR  LE +L R   HP L 
Sbjct: 117 LLVYYPHI--VVPPLPEKRAEFVWHKL--SADNMDPDFVERRRIGLENFLLRIASHPILC 172

Query: 254 QDPDLRQFL-ESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQ 312
           +D     FL +       VN       G     +    A+N  T ++   D  F + +  
Sbjct: 173 RDKIFYLFLTQEGNWKETVNE-----TGFQLKADSRLKALN-ATFRVKNPDKRFTDLKHY 226

Query: 313 FENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEE 372
            + L   +  L + V A V  R               + G  + H    R  S+ + +E+
Sbjct: 227 SDELQSVISHL-LRVRARVADR---------------LYGVYKVHGNYGRVFSEWSAIEK 270

Query: 373 KI-DQLHQEQAFADFYM------------FSELLSDYIRLIAAVKGVF-DHRMKCWQKWE 418
           ++ D L       D Y             +++ L +Y+    A++ V   H +  +    
Sbjct: 271 EMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDLEM 330

Query: 419 DAQITLLKKREAE----------------AKMMVANKPD----KIQQAKNEIREWEAKVQ 458
            AQ    KK++ E                 K+     P+    +I+  + +I E E +++
Sbjct: 331 AAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLK 390

Query: 459 QGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYW 508
               +  +  K    ++ RF++++ +D K  +I Y    +   ++ I+ W
Sbjct: 391 SKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQVW 440


>gi|23111030 sorting nexin 12 [Homo sapiens]
          Length = 162

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 39/128 (30%), Positives = 64/128 (50%), Gaps = 4/128 (3%)

Query: 142 IEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHV 201
           +EI + +P+ VG G   +  Y V  +T+L +F   E  V+RR+SDF  L ++L       
Sbjct: 30  LEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELER---DS 86

Query: 202 GYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQF 261
             +VPP P K++      + G E      F+E+RR  LE+++ +   HP    +  L  F
Sbjct: 87  KIVVPPLPGKALKRQLPFR-GDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMF 145

Query: 262 LESSELPR 269
           L+   + R
Sbjct: 146 LQEEAIDR 153


>gi|23943858 sorting nexin 8 [Homo sapiens]
          Length = 465

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 89/420 (21%), Positives = 160/420 (38%), Gaps = 83/420 (19%)

Query: 77  ATEEVSLDSPEREPILSSEPSPAVTPVTPTTLI----APRIESKSMSAPVIFDRSREEIE 132
           A  E   D  E +P  S  P+P    + P  ++    AP         P++   + +E+ 
Sbjct: 16  AAAEAEADE-EADPPASDLPTPQA--IEPQAIVQQVPAPSRMQMPQGNPLLLSHTLQELL 72

Query: 133 EEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHS 192
                D   +E+    PEK G  +  ++ Y V+++   S       SV RR++DF+    
Sbjct: 73  AR---DTVQVEL---IPEKKGLFLK-HVEYEVSSQRFKS-------SVYRRYNDFVVFQE 118

Query: 193 KLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTL 252
            L  K+ +   +VP  P K ++G  +           EF+E RR AL+R++    +HP  
Sbjct: 119 MLLHKFPY--RMVPALPPKRMLGADR-----------EFIEARRRALKRFVNLVARHPLF 165

Query: 253 LQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMN-----------E 301
            +D  L+ FL            + SG+ +   + ++A  V    +              +
Sbjct: 166 SEDVVLKLFL------------SFSGSDVQNKLKESAQCVGDEFLNCKLATRAKDFLPAD 213

Query: 302 SDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLG--------- 352
             A F   ++   N+     KL    E +     + +A+   F K  + +G         
Sbjct: 214 IQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAIGSDTTPLPSW 273

Query: 353 ---NSEDHTALSRAL-------SQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAA 402
              NS    +L +AL       + LA+   +  +  +        +F +LL  Y  L   
Sbjct: 274 AALNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDLLQSYKDLCER 333

Query: 403 -VKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGE 461
             KGV     +   K+       L KR+  +      +P+ ++Q ++ I E E  +Q  E
Sbjct: 334 HEKGVLHKHQRALHKYS------LMKRQMMSATAQNREPESVEQLESRIVEQENAIQTME 387


>gi|7706706 sorting nexin 9 [Homo sapiens]
          Length = 595

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 99/497 (19%), Positives = 183/497 (36%), Gaps = 84/497 (16%)

Query: 29  TSTVSTLESSPSSPE----PASLPAEDISANSNGPKPTEVVLDDDREDLFAEATEEVSLD 84
           T+T +  +++   P+    PA+   +D   + +GPK +    D +  D            
Sbjct: 138 TNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKDSESADAGGAQRGNSRAS 197

Query: 85  SPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIF-DRSREEIEEEANGDIFDIE 143
           S   +  L+  P  A  P T   L+A ++       P+I  D     +   +  D     
Sbjct: 198 SSSMKIPLNKFPGFA-KPGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCV--- 253

Query: 144 IGVSDPEKVGD--GMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHV 201
             V+DP K     G+ +Y+ Y++T        + +  SV  R+  F  L+ +L  K+   
Sbjct: 254 --VADPRKGSKMYGLKSYIEYQLTP-------TNTNRSVNHRYKHFDWLYERLLVKF-GS 303

Query: 202 GYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQF 261
              +P  P+K + G  +           EF++ R   L+ ++ R  +HP + +    +QF
Sbjct: 304 AIPIPSLPDKQVTGRFE----------EEFIKMRMERLQAWMTRMCRHPVISESEVFQQF 353

Query: 262 L------ESSELPRAVNTQALSGAGI------------LRMVNKAADAVNKMTIKMNES- 302
           L      E     R      L+G  I            L  + +  +AV K T  M++  
Sbjct: 354 LNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGV 413

Query: 303 DAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSR 362
                  Q+ ++     L K +  +       K L +    F+ S       +  T L+ 
Sbjct: 414 KELLTVGQEHWKRCTGPLPKEYQKI------GKALQSLATVFSSS-----GYQGETDLND 462

Query: 363 ALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQI 422
           A+++  +  E+I  L  EQ   D +   E   +Y   +     +        +K +    
Sbjct: 463 AITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVK---- 518

Query: 423 TLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKER 482
                   E+  +VA     +Q  +N ++               +S  ++ E+  F   R
Sbjct: 519 --------ESDKLVATSKITLQDKQNMVKR-----------VSIMSYALQAEMNHFHSNR 559

Query: 483 VKDFKTVIIKYLESLVQ 499
           + D+ +VI  YLE  VQ
Sbjct: 560 IYDYNSVIRLYLEQQVQ 576


>gi|23111026 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 39/125 (31%), Positives = 62/125 (49%), Gaps = 15/125 (12%)

Query: 142 IEIGVSDPEKVGDGM-NAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLH 200
           I + V DP    +G  N+Y+ Y++   T+   F+     V+RR+ +F+ L  +L     +
Sbjct: 17  ITVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQR---N 73

Query: 201 VGYI-VPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLR 259
            G + VP  P KS    T          S EF+EKRR  L+ +L++ ++   LL D  L 
Sbjct: 74  AGLVPVPELPGKSTFFGT----------SDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLH 123

Query: 260 QFLES 264
            FL+S
Sbjct: 124 LFLQS 128


>gi|23111028 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 39/125 (31%), Positives = 62/125 (49%), Gaps = 15/125 (12%)

Query: 142 IEIGVSDPEKVGDGM-NAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLH 200
           I + V DP    +G  N+Y+ Y++   T+   F+     V+RR+ +F+ L  +L     +
Sbjct: 17  ITVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQR---N 73

Query: 201 VGYI-VPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLR 259
            G + VP  P KS    T          S EF+EKRR  L+ +L++ ++   LL D  L 
Sbjct: 74  AGLVPVPELPGKSTFFGT----------SDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLH 123

Query: 260 QFLES 264
            FL+S
Sbjct: 124 LFLQS 128


>gi|23397574 sorting nexin 33 [Homo sapiens]
          Length = 574

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 81/381 (21%), Positives = 142/381 (37%), Gaps = 76/381 (19%)

Query: 146 VSDPEKVGD--GMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGY 203
           V DP K     G+ +Y++Y++T   + S        V RR+  F  L+++L  K+  +  
Sbjct: 234 VEDPTKQTKFKGIKSYISYKLTPTHAAS-------PVYRRYKHFDWLYNRLLHKFTVIS- 285

Query: 204 IVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLE 263
            VP  PEK   G  +           +F+EKR+  L  ++     HP L Q    + FL 
Sbjct: 286 -VPHLPEKQATGRFE----------EDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLS 334

Query: 264 SSE------LPRAVNTQALSGAGI------------LRMVNKAADAVNKMTIKMNESDAW 305
             +        R      + GA              L+ V    D     + KM++S   
Sbjct: 335 CLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDS--- 391

Query: 306 FEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAF--AKSAAMLGNSEDHTALSRA 363
                 Q   +  +L + HV        RKE     +AF     +  +       AL+ A
Sbjct: 392 ----VLQLSTVASELVRKHVG-----GFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSA 442

Query: 364 LSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQIT 423
           +S      E I ++  EQ   D +   + LS Y  L++    +   +   + K +++Q  
Sbjct: 443 ISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQ-- 500

Query: 424 LLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERV 483
               R ++   MV ++ D I+                 R    +   ++ E+  F + R 
Sbjct: 501 ----RMSDEGRMVQDEADGIR-----------------RRCRVVGFALQAEMNHFHQRRE 539

Query: 484 KDFKTVIIKYLESLVQTQQQL 504
            DFK ++  YL   +   Q++
Sbjct: 540 LDFKHMMQNYLRQQILFYQRV 560


>gi|88703043 sorting nexin 6 isoform a [Homo sapiens]
          Length = 290

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 54/264 (20%), Positives = 111/264 (42%), Gaps = 20/264 (7%)

Query: 233 EKRRAALERYLQRTVKHPTLLQDPDLRQFLE-SSELPRAVNTQALSGAGILRMVNKAADA 291
           +K  A  E +L R   HP L +D +   FLE + +L      +        + + K+AD 
Sbjct: 22  KKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADG 81

Query: 292 VNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAML 351
           V    +K  + D +FE ++        +++      + +    K  + +      S   L
Sbjct: 82  VIVSGVK--DVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYAL 139

Query: 352 GNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRM 411
           G ++D T + +   +++E+ +K  ++    +  +    S+LL  Y+R   A K +   R 
Sbjct: 140 G-TQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRS 198

Query: 412 KCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTI 471
           +    +E+A   L                DK +    ++ + E   Q   + FE+IS++ 
Sbjct: 199 RSLVDYENANKAL----------------DKARAKNKDVLQAETSQQLCCQKFEKISESA 242

Query: 472 RKEVGRFEKERVKDFKTVIIKYLE 495
           ++E+  F+  RV  F+  +++  E
Sbjct: 243 KQELIDFKTRRVAAFRKNLVELAE 266


>gi|23111023 sorting nexin 10 [Homo sapiens]
          Length = 201

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 33/124 (26%), Positives = 63/124 (50%), Gaps = 12/124 (9%)

Query: 142 IEIGVSDPE-KVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLH 200
           + + V DP  +  D  ++Y+ Y +   T+   F+     V+RR+ +F+ L  +L S  L 
Sbjct: 11  VSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWLRQRLQSNALL 70

Query: 201 VGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQ 260
           V   +P  P K++           + ++ + V++RR  LE +L++ +++  LL D  L  
Sbjct: 71  VQ--LPELPSKNLFF---------NMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHL 119

Query: 261 FLES 264
           FL+S
Sbjct: 120 FLQS 123


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 53/223 (23%), Positives = 102/223 (45%), Gaps = 18/223 (8%)

Query: 285  VNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAF 344
            + K  +AV ++    + ++    E  Q+ E L+ +L+  H  +++ +   +EL       
Sbjct: 1034 LEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRD----- 1088

Query: 345  AKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFS---ELLSDYIRLIA 401
                A L   E +T +    ++L E + +I+   QE    D  +     EL     ++  
Sbjct: 1089 VLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTH 1148

Query: 402  AVKGVFDHRMKCWQKWEDAQITLLKKREAEAK---MMVANKPDKIQQAKNEIREWEAKVQ 458
                + +HR +  QK    + TL +K E E K     + +  DK+Q AK ++RE E  + 
Sbjct: 1149 LDMTIREHRGEMEQKIIKLEGTL-EKSELELKECNKQIESLNDKLQNAKEQLREKEFIML 1207

Query: 459  QGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQ 501
            Q E++  Q+ K I +      ++R+K+ ++V +K  E  + TQ
Sbjct: 1208 QNEQEISQLKKEIER-----TQQRMKEMESV-MKEQEQYIATQ 1244



 Score = 33.1 bits (74), Expect = 0.63
 Identities = 51/273 (18%), Positives = 104/273 (38%), Gaps = 35/273 (12%)

Query: 232 VEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADA 291
           +E   + L+  +        L+Q+  L +   SS+L   +  +      + + + +   A
Sbjct: 653 IEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVA 712

Query: 292 VNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAML 351
            + +  K  E +    EK ++  +L+  +   H  +               AF K+  + 
Sbjct: 713 YSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKI-------------CLAFEKAKKI- 758

Query: 352 GNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRM 411
            + E H  + + + +L    EK DQ  +EQ        S L  D I              
Sbjct: 759 -HLEQHKEMEKQIERLEAQLEKKDQQFKEQEKT----MSMLQQDII-------------- 799

Query: 412 KCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTI 471
            C Q   ++   LL + + E K     K + ++  +N++ E   KV+Q +   E   + +
Sbjct: 800 -CKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEEL 858

Query: 472 RKEVGRFEKERVKDFKTVIIKYLESLVQTQQQL 504
              + + E  + K F+  + K  E +   Q++L
Sbjct: 859 VLHLNQLEGNKEK-FEKQLKKKSEEVYCLQKEL 890


>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
          Length = 624

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 85/392 (21%), Positives = 140/392 (35%), Gaps = 86/392 (21%)

Query: 140 FDIEIGVSDPEKVGD--GMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASK 197
           +  +  + DP K     GM +Y++Y++         + ++  V RR+  F  L+++LA K
Sbjct: 274 YPFQCTIDDPTKQTKFKGMKSYISYKLVP-------THTQVPVHRRYKHFDWLYARLAEK 326

Query: 198 YLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPD 257
           +  +   VP  PEK   G  +           +F+ KRR  L  ++     HP L Q   
Sbjct: 327 FPVIS--VPHLPEKQATGRFE----------EDFISKRRKGLIWWMNHMASHPVLAQCDV 374

Query: 258 LRQFL------------------ESSELPRAVNTQALS----GAGILRMVNKAADAVNKM 295
            + FL                  E  E+  A     LS     A  L+ V    D     
Sbjct: 375 FQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCF 434

Query: 296 TIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAF--AKSAAMLGN 353
           T KM++S         +F              + +   +KE      +F     A  L  
Sbjct: 435 TKKMDDSALQLNHTANEFAR------------KQVTGFKKEYQKVGQSFRGLSQAFELDQ 482

Query: 354 SEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKC 413
                 L++A++   +  + I +L  EQ   D     +LL+ Y   +A    +   +   
Sbjct: 483 QAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGA 542

Query: 414 WQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRK 473
             K +++      +R  E   M   K D IQ   N                  IS     
Sbjct: 543 LTKVKES------RRHVEEGKMEVQKADGIQDRCN-----------------TISFATLA 579

Query: 474 EVGRFEKERVKDFKTVIIKYLESLVQTQQQLI 505
           E+  F + RV+DFK+ +  +L      QQQ+I
Sbjct: 580 EIHHFHQIRVRDFKSQMQHFL------QQQII 605


>gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [Homo
           sapiens]
          Length = 464

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 30/101 (29%), Positives = 52/101 (51%), Gaps = 12/101 (11%)

Query: 163 RVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVG 222
           R T    L    +SE+ V RR+++F  L++ L  ++  +   +P    K I G       
Sbjct: 30  RFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPA---KRIFG------- 79

Query: 223 KEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLE 263
             D+   +F+++RRA L  ++Q  V++P L   PD+R FL+
Sbjct: 80  --DNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQ 118


>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
           sapiens]
          Length = 496

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 30/101 (29%), Positives = 52/101 (51%), Gaps = 12/101 (11%)

Query: 163 RVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVG 222
           R T    L    +SE+ V RR+++F  L++ L  ++  +   +P    K I G       
Sbjct: 30  RFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPA---KRIFG------- 79

Query: 223 KEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLE 263
             D+   +F+++RRA L  ++Q  V++P L   PD+R FL+
Sbjct: 80  --DNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQ 118


>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
           sapiens]
          Length = 496

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 30/101 (29%), Positives = 52/101 (51%), Gaps = 12/101 (11%)

Query: 163 RVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVG 222
           R T    L    +SE+ V RR+++F  L++ L  ++  +   +P    K I G       
Sbjct: 30  RFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPA---KRIFG------- 79

Query: 223 KEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLE 263
             D+   +F+++RRA L  ++Q  V++P L   PD+R FL+
Sbjct: 80  --DNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQ 118


>gi|68800430 HCLS1 binding protein 3 [Homo sapiens]
          Length = 392

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 48/206 (23%), Positives = 88/206 (42%), Gaps = 37/206 (17%)

Query: 118 MSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKV-GDGMNAYMAYRVTTKTSLSMFSKS 176
           M +P +   SR  ++    G    +++ V   ++V G  M+ ++ Y++   T L+ F  +
Sbjct: 1   MQSPAVLVTSRR-LQNAHTG----LDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSA 55

Query: 177 --------EFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSS 228
                   +F V +++S+    + KL+S+Y      +PP P K +       VG+ D   
Sbjct: 56  KHRPEDVVQFLVSKKYSEIEEFYQKLSSRYAAAS--LPPLPRKVLF------VGESD--- 104

Query: 229 TEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKA 288
              + +RRA     L+   K   L   P+L +FL          T++   AG+    +  
Sbjct: 105 ---IRERRAVFNEILRCVSKDAELAGSPELLEFL---------GTRSPGAAGLTSRDSSV 152

Query: 289 ADAVNKMTIKMNESDAWFEEKQQQFE 314
            D  +  T    E+  +FEE+ Q  E
Sbjct: 153 LDGTDSQTGNDEEAFDFFEEQDQVAE 178


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 72/341 (21%), Positives = 136/341 (39%), Gaps = 48/341 (14%)

Query: 208  APEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSEL 267
            A E+  +    VK+ ++D    +   K     E   QR  K         L Q  E+ +L
Sbjct: 1610 AQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEK---------LSQ--EAEKL 1658

Query: 268  PRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLD-------QQL 320
             +     A     + R   K A    K+    N      EE  Q+ +NLD       Q+L
Sbjct: 1659 AQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQEL 1718

Query: 321  RKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQ---- 376
             +L   +E L    +EL+       +    L   E+  A  R   +L+E E K+ Q    
Sbjct: 1719 EELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQR--EKLSEEETKLAQEEEL 1776

Query: 377  -LHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWE-----------DAQITL 424
             + +++  A      ++  +  RL    + + + +MK  QK E           +  I  
Sbjct: 1777 LIQEKEKLAQHK--EKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILY 1834

Query: 425  LKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEK---- 480
             KK  A+ K  +A + +K+ Q K  +   + ++   ++   Q    ++ ++G F K    
Sbjct: 1835 QKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQ----VKNKLGMFNKILAQ 1890

Query: 481  --ERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519
              E++   K  +IK  E L +T+++L++  ++   + + +A
Sbjct: 1891 VEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLA 1931



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 22/99 (22%), Positives = 48/99 (48%), Gaps = 4/99 (4%)

Query: 408  DHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQI 467
            D ++K W++W+     +L  +  E +     +    ++   E  E E +V + +R  ++ 
Sbjct: 1513 DKKLK-WEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEE 1571

Query: 468  SK--TIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQL 504
             K   I ++  R EK+R ++ +  + +  E L Q ++QL
Sbjct: 1572 HKWARIHRKRARAEKKRAQE-ERKLAQEEEKLAQEERQL 1609


>gi|157502171 sorting nexin 19 [Homo sapiens]
          Length = 992

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 71/284 (25%), Positives = 114/284 (40%), Gaps = 56/284 (19%)

Query: 12  DGKPTDFEDLEDGEDLFTST---VSTLESSPS---SPEPASLPAEDISANSN----GPKP 61
           DG+ ++  + E+G    T T   VSTL S P          +   D++A+      GP+ 
Sbjct: 415 DGEASEGAEAEEGPGTETETGLPVSTLNSCPEIHIDTADKEIEQGDVTASVTALLEGPEK 474

Query: 62  TEVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAP 121
           T          L  + T +VS   P   P+L S   P   P++  T     + S     P
Sbjct: 475 T---CPSRPSCLEKDLTNDVSSLDPTLPPVLLSSSPPG--PLSSATFSFEPLSSPD--GP 527

Query: 122 VIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEF--- 178
           VI    R             I   ++  E  G G + Y  Y V  +T+L   + S     
Sbjct: 528 VIIQNLR-------------ITGTITAREHSGTGFHPYTLYTVKYETALDGENSSGLQQL 574

Query: 179 ---SVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTK----VKVGKEDSSSTEF 231
              +V RR+ +FL L ++L  K     +I      K++ G  K    +  G  DS   + 
Sbjct: 575 AYHTVNRRYREFLNLQTRLEEKPDLRKFI------KNVKGPKKLFPDLPFGNMDS---DR 625

Query: 232 VEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQA 275
           VE R++ LE +L++    P +    ++++FL       A+NT A
Sbjct: 626 VEARKSLLESFLKQLCAIPEIANSEEVQEFL-------ALNTDA 662


>gi|154091028 sorting nexin 29 [Homo sapiens]
          Length = 428

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 33/106 (31%), Positives = 53/106 (50%), Gaps = 20/106 (18%)

Query: 153 GDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHV-GYIVPPAPEK 211
           G   NA+  Y+V  +         E+++ RR+++F  LH KL +KY  V  Y  PP    
Sbjct: 284 GKAANAFHVYQVYIR-----IKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPP---- 334

Query: 212 SIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPD 257
                 K  +G +D+   +FVE+RR  L+ YL R+V +  +   P+
Sbjct: 335 ------KKAIGNKDA---KFVEERRKQLQNYL-RSVMNKVIQMVPE 370


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,101,364
Number of Sequences: 37866
Number of extensions: 888300
Number of successful extensions: 4926
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 332
Number of HSP's that attempted gapping in prelim test: 4358
Number of HSP's gapped (non-prelim): 812
length of query: 519
length of database: 18,247,518
effective HSP length: 107
effective length of query: 412
effective length of database: 14,195,856
effective search space: 5848692672
effective search space used: 5848692672
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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