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Search of human proteins with 22749259
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22749259 poly (ADP-ribose) polymerase family, member 15
isoform 2 [Homo sapiens]
(444 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22749259 poly (ADP-ribose) polymerase family, member 15 isofo... 903 0.0
gi|165377137 poly (ADP-ribose) polymerase family, member 15 isof... 860 0.0
gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Hom... 283 2e-76
gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens] 140 3e-33
gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo sap... 140 3e-33
gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Hom... 134 2e-31
gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Hom... 123 3e-28
gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens] 102 7e-22
gi|226371718 poly (ADP-ribose) polymerase family, member 9 isofo... 85 1e-16
gi|226371716 poly (ADP-ribose) polymerase family, member 9 isofo... 85 1e-16
gi|226371714 poly (ADP-ribose) polymerase family, member 9 isofo... 85 1e-16
gi|226371712 poly (ADP-ribose) polymerase family, member 9 isofo... 85 1e-16
gi|226371710 poly (ADP-ribose) polymerase family, member 9 isofo... 85 1e-16
gi|226371706 poly (ADP-ribose) polymerase family, member 9 isofo... 85 1e-16
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 67 3e-11
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 57 4e-08
gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens] 55 2e-07
gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens] 52 8e-07
gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens] 52 8e-07
gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens] 52 8e-07
gi|13569840 MACRO domain containing 1 [Homo sapiens] 44 2e-04
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo... 41 0.002
gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo... 41 0.002
gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens] 40 0.003
gi|207450721 ganglioside induced differentiation associated prot... 32 1.5
gi|8923143 ganglioside induced differentiation associated protei... 32 1.5
gi|4504993 leukemia inhibitory factor receptor precursor [Homo s... 29 9.8
gi|189083786 leukemia inhibitory factor receptor precursor [Homo... 29 9.8
gi|239757103 PREDICTED: similar to fos39347_1 [Homo sapiens] 29 9.8
gi|239751609 PREDICTED: hypothetical protein XP_002347928 [Homo ... 29 9.8
>gi|22749259 poly (ADP-ribose) polymerase family, member 15 isoform
2 [Homo sapiens]
Length = 444
Score = 903 bits (2334), Expect = 0.0
Identities = 444/444 (100%), Positives = 444/444 (100%)
Query: 1 MLQRIGLIFLHNIVVVSNCFYFQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCF 60
MLQRIGLIFLHNIVVVSNCFYFQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCF
Sbjct: 1 MLQRIGLIFLHNIVVVSNCFYFQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCF 60
Query: 61 TAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVL 120
TAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVL
Sbjct: 61 TAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVL 120
Query: 121 AAQPHRDFIITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAG 180
AAQPHRDFIITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAG
Sbjct: 121 AAQPHRDFIITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAG 180
Query: 181 KNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQST 240
KNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQST
Sbjct: 181 KNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQST 240
Query: 241 FSMTTCNLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLW 300
FSMTTCNLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLW
Sbjct: 241 FSMTTCNLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLW 300
Query: 301 QSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAV 360
QSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAV
Sbjct: 301 QSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAV 360
Query: 361 DASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNT 420
DASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNT
Sbjct: 361 DASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNT 420
Query: 421 RSPKLFVVFFDNQAYPEYLITFTA 444
RSPKLFVVFFDNQAYPEYLITFTA
Sbjct: 421 RSPKLFVVFFDNQAYPEYLITFTA 444
>gi|165377137 poly (ADP-ribose) polymerase family, member 15 isoform
1 [Homo sapiens]
Length = 678
Score = 860 bits (2221), Expect = 0.0
Identities = 424/435 (97%), Positives = 428/435 (98%)
Query: 10 LHNIVVVSNCFYFQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGA 69
+H +V ++ QAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGA
Sbjct: 244 VHFLVYTNDDEGCQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGA 303
Query: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI 129
ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI
Sbjct: 304 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI 363
Query: 130 ITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADN 189
ITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADN
Sbjct: 364 ITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADN 423
Query: 190 IIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLP 249
IIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLP
Sbjct: 424 IIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLP 483
Query: 250 EHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQ 309
EHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQ
Sbjct: 484 EHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQ 543
Query: 310 MDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDT 369
MDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDT
Sbjct: 544 MDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDT 603
Query: 370 YSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVF 429
YSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVF
Sbjct: 604 YSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVF 663
Query: 430 FDNQAYPEYLITFTA 444
FDNQAYPEYLITFTA
Sbjct: 664 FDNQAYPEYLITFTA 678
Score = 46.2 bits (108), Expect = 6e-05
Identities = 35/144 (24%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Query: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSG-VSRAILEGAGQAVESECAVLAAQPHR-- 126
+ ++ +GD+ DVIVNS G +SRA L+ AG ++ E +
Sbjct: 89 LNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRRETEEKV 148
Query: 127 -DFIITPGGCLKCKIIIHVP------GGKDVRKTVTSVLEEC----EQRKYTSVSLPAIG 175
+ +T G L CK ++H G + + + +++++C E ++S++ P IG
Sbjct: 149 GNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITFPMIG 208
Query: 176 TGNAGKNPITVADNIIDAIVDFSS 199
TG+ A I+ + ++SS
Sbjct: 209 TGSLQFPKAVFAKLILSEVFEYSS 232
>gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Homo
sapiens]
Length = 1801
Score = 283 bits (725), Expect = 2e-76
Identities = 129/196 (65%), Positives = 155/196 (79%)
Query: 247 NLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVK 306
++P HW+DM Q FC+V+L P EYNT+ KF +TCS + IEKIERIQN LW SYQ K
Sbjct: 1604 DIPAHWSDMKQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAK 1663
Query: 307 KRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSA 366
K+ MD KN NE+ LFHGTDA SVP+VN++GFNRS AGKNAV+YGKGTYFAV+A+YSA
Sbjct: 1664 KKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSA 1723
Query: 367 KDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLF 426
DTYS+PD+NGRKH+Y VRVLTG++T G L+ PP KNP NPTDL+D+VT+N P LF
Sbjct: 1724 NDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLF 1783
Query: 427 VVFFDNQAYPEYLITF 442
V F+D QAYPEYLITF
Sbjct: 1784 VAFYDYQAYPEYLITF 1799
Score = 233 bits (594), Expect = 3e-61
Identities = 127/233 (54%), Positives = 164/233 (70%)
Query: 10 LHNIVVVSNCFYFQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGA 69
+H ++ S+ QAF DEF + N +IP A DTQG GTVS P YEMKIG+
Sbjct: 1167 VHFLLHPSDHENIQAFSDEFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGS 1226
Query: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI 129
I FQVA+GDI E+ DVIVNST+ +FN K+GVS+AILE AGQ VE EC+ A Q D+I
Sbjct: 1227 IIFQVASGDITKEEADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYI 1286
Query: 130 ITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADN 189
IT GG L+CK IIHV GG DV+ +V+SVL+ECE++ Y+S+ LPAIGTGNA ++P VA+
Sbjct: 1287 ITGGGFLRCKNIIHVIGGNDVKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDKVAEA 1346
Query: 190 IIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFS 242
IIDAI DF + S S+K VKVVIF P++L++FY +MKKR+ + + QS S
Sbjct: 1347 IIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLSSQQSVMS 1399
Score = 57.0 bits (136), Expect = 3e-08
Identities = 53/211 (25%), Positives = 90/211 (42%), Gaps = 20/211 (9%)
Query: 39 KARIPMAGDTQGVVGTVSKPCFTAYE----MKIGAITFQVATGDIATEQVDVIVNSTART 94
KA +P G+ + P T++E + G + + + + DV+VNS
Sbjct: 979 KATLPDTAAPPGLPPAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLD 1038
Query: 95 FNRKSG-VSRAILEGAGQAVESECAVLA---AQPHRDFIITPGGCLKCKIIIHVP----- 145
G +S+++LE AG ++ E + A + T L C+ ++HV
Sbjct: 1039 LVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWR 1098
Query: 146 -GGKDVRKTVTSVLEEC----EQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQ 200
G K + ++ EC E S++ PAIGTGN G A+ II + FSS+
Sbjct: 1099 NGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSK 1158
Query: 201 HSTPSLKTVKVVIFQPELLNI--FYDSMKKR 229
+ +L+ V ++ + NI F D +R
Sbjct: 1159 NQLKTLQEVHFLLHPSDHENIQAFSDEFARR 1189
Score = 52.0 bits (123), Expect = 1e-06
Identities = 45/185 (24%), Positives = 84/185 (45%), Gaps = 17/185 (9%)
Query: 59 CFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECA 118
CF+ + G + V GD+A VDV+VN++ G++ A+ + AG ++++C
Sbjct: 792 CFSRTVLAPGVVLI-VQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCD 850
Query: 119 VLAAQPHR----DFIITPGGCLKCKIIIHVPGGK-----------DVRKTVTSVLEECEQ 163
+ + R + I+ G L +IH G + +R+ V L E+
Sbjct: 851 QIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEK 910
Query: 164 RKYTSVSLPAIGTGNAGKNPITVADNIIDAIVD-FSSQHSTPSLKTVKVVIFQPELLNIF 222
KY S+++PAI +G G + I+ AI + F + LK + +V + + F
Sbjct: 911 YKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAF 970
Query: 223 YDSMK 227
+++K
Sbjct: 971 AEAVK 975
>gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens]
Length = 701
Score = 140 bits (352), Expect = 3e-33
Identities = 84/217 (38%), Positives = 116/217 (53%), Gaps = 15/217 (6%)
Query: 238 QSTFSMTTCN--------LPEHWTD--MNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYA 287
Q +M TCN +P++W + F + L EY + + F RT Y
Sbjct: 466 QDVTTMQTCNTKFPGPKSIPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLPFYF 525
Query: 288 IEKIERIQNAFLWQSYQVKKRQMDIKNDHKN-NERLLFHGTDADSVPYVNQHGFNRSCAG 346
++KIER+QN LW+ YQ +K QM +N K +ER LFHGT A V + Q F+ G
Sbjct: 526 VQKIERVQNLALWEVYQWQKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVCG 585
Query: 347 KNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNP 406
+ SYGKG+YFA DA+YS YSK D+ M++ RVL G F +G A V PP K
Sbjct: 586 VHGTSYGKGSYFARDAAYS--HHYSKSDTQTHT-MFLARVLVGEFVRGNASFVRPPAKEG 642
Query: 407 HNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 443
+ +DS N+ P +FV+F +Q YPEY+I +T
Sbjct: 643 WS-NAFYDSCVNSVSDPSIFVIFEKHQVYPEYVIQYT 678
>gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo
sapiens]
Length = 657
Score = 140 bits (352), Expect = 3e-33
Identities = 84/208 (40%), Positives = 119/208 (57%), Gaps = 10/208 (4%)
Query: 243 MTTCNL-PEHWTDMN-HQLFCMVQLEPGQSEYNTIKDKFTRTCSS--YAIEKIERIQNAF 298
+T+ N PE W M+ Q F V + Y I + F +T Y I +I R+QN F
Sbjct: 443 VTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQF 502
Query: 299 LWQSYQVKKRQMDIK---NDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKG 355
LW+ Y+ KK M+ K D NER LFHGT D V + +H F+ GK+A +G+G
Sbjct: 503 LWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQG 562
Query: 356 TYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPT-DLFD 414
+YFA ASYS +SK S G M++ +VLTG +T G G+ PPP NP + T DL+D
Sbjct: 563 SYFAKKASYS--HNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYD 620
Query: 415 SVTNNTRSPKLFVVFFDNQAYPEYLITF 442
S +N P++FV+F D+Q+YP ++I +
Sbjct: 621 SCVDNFFEPQIFVIFNDDQSYPYFVIQY 648
>gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Homo
sapiens]
Length = 1025
Score = 134 bits (337), Expect = 2e-31
Identities = 66/158 (41%), Positives = 100/158 (63%)
Query: 284 SSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRS 343
SS + ++ER+ + L Q Y++ + ++ + + + E++L+HGT A +VP + HGFNRS
Sbjct: 846 SSIRVVRVERVSHPLLQQQYELYRERLLQRCERRPVEQVLYHGTTAPAVPDICAHGFNRS 905
Query: 344 CAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPP 403
G+NA YGKG YFA AS S +D YS P+++G K ++V RVLTG + +GR GL PP
Sbjct: 906 FCGRNATVYGKGVYFARRASLSVQDRYSPPNADGHKAVFVARVLTGDYGQGRRGLRAPPL 965
Query: 404 KNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLIT 441
+ P + +DS + P +FV+F D QA P +LIT
Sbjct: 966 RGPGHVLLRYDSAVDCICQPSIFVIFHDTQALPTHLIT 1003
>gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Homo
sapiens]
Length = 338
Score = 123 bits (309), Expect = 3e-28
Identities = 77/216 (35%), Positives = 119/216 (55%), Gaps = 24/216 (11%)
Query: 248 LPEHWTDMNHQL-FCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVK 306
+P HW ++N Q+ + ++ L EYN + + F +T I++I+RIQN LW+ + K
Sbjct: 125 MPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRK 184
Query: 307 KRQMDIKNDHKN-NERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYS 365
K Q+ K NE++LFHGT ++ V + H F+ G + +GKGTYFA DA+YS
Sbjct: 185 KAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYS 244
Query: 366 AKDTYSKPD-SNGR------------------KHMYVVRVLTGVFTKGRAGLVTPPPKNP 406
++ + K D +G K M++ RVL G + G + + PP K+
Sbjct: 245 SR--FCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKD- 301
Query: 407 HNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITF 442
+ +L+DS ++T +PK+FVVF NQ YPEYLI F
Sbjct: 302 GSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDF 337
>gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens]
Length = 902
Score = 102 bits (254), Expect = 7e-22
Identities = 72/238 (30%), Positives = 115/238 (48%), Gaps = 18/238 (7%)
Query: 207 KTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLP-EHWTDMNHQLFCMVQL 265
KT K VI +P + +Y KR S+ S+T P E + ++ + + + ++
Sbjct: 674 KTQKDVIRRPTFVPQWYVQQMKRGPDHQPAKTSSVSLTATFRPQEDFCFLSSKKYKLSEI 733
Query: 266 EPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFH 325
EY + + F + ++ IEKI++I+N+ L + KK QM K +LLF+
Sbjct: 734 HHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQM------KEEGKLLFY 787
Query: 326 GTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVR 385
T V + + F+ + YGKG YFA DA YS K+ P M+V +
Sbjct: 788 ATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNC---PYDAKNVVMFVAQ 844
Query: 386 VLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 443
VL G FT+G +PPP+ FDS + +P +FV+F +Q YP+Y+I +T
Sbjct: 845 VLVGKFTEGNITYTSPPPQ--------FDSCVDTRSNPSVFVIFQKDQVYPQYVIEYT 894
>gi|226371718 poly (ADP-ribose) polymerase family, member 9 isoform
c [Homo sapiens]
Length = 710
Score = 85.1 bits (209), Expect = 1e-16
Identities = 67/196 (34%), Positives = 96/196 (48%), Gaps = 14/196 (7%)
Query: 52 VGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQ 111
+G + P F A M + +T Q+ G I + DVIVNS V+++IL+ AG
Sbjct: 266 LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGV 323
Query: 112 AVESE-CAVLAAQPHRD--FIITPGGCLKCKIIIHV------PGGKDVRKTVTSVLEECE 162
++SE A A Q R ++T G L CK I HV P + ++ + LE+C
Sbjct: 324 EMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCI 383
Query: 163 QRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQP--ELLN 220
++ TS+S PA+GTGN T A+ + D ++ F+ H L TVK VIF E+
Sbjct: 384 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQL-TVKFVIFPTDLEIYK 442
Query: 221 IFYDSMKKRDLSASLN 236
F M KR SLN
Sbjct: 443 AFSSEMAKRSKMLSLN 458
Score = 38.1 bits (87), Expect = 0.016
Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 17/125 (13%)
Query: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHR--- 126
I V D+ T VD +VN+ G++ A+++ G ++ E A+ +
Sbjct: 83 IELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSA 142
Query: 127 -DFIITPGGCLKCKIIIHVPGGK-----------DVRKTVTSVLEEC--EQRKYTSVSLP 172
+ +T G L CK IIH G + +++ + S+L + +V++P
Sbjct: 143 GEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIP 202
Query: 173 AIGTG 177
A+ +G
Sbjct: 203 ALSSG 207
>gi|226371716 poly (ADP-ribose) polymerase family, member 9 isoform
b [Homo sapiens]
Length = 819
Score = 85.1 bits (209), Expect = 1e-16
Identities = 67/196 (34%), Positives = 96/196 (48%), Gaps = 14/196 (7%)
Query: 52 VGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQ 111
+G + P F A M + +T Q+ G I + DVIVNS V+++IL+ AG
Sbjct: 266 LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGV 323
Query: 112 AVESE-CAVLAAQPHRD--FIITPGGCLKCKIIIHV------PGGKDVRKTVTSVLEECE 162
++SE A A Q R ++T G L CK I HV P + ++ + LE+C
Sbjct: 324 EMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCI 383
Query: 163 QRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQP--ELLN 220
++ TS+S PA+GTGN T A+ + D ++ F+ H L TVK VIF E+
Sbjct: 384 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQL-TVKFVIFPTDLEIYK 442
Query: 221 IFYDSMKKRDLSASLN 236
F M KR SLN
Sbjct: 443 AFSSEMAKRSKMLSLN 458
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Query: 290 KIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNA 349
K+E+I N L ++Q KK+ M+ K + LF V + GF R +
Sbjct: 635 KVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCD 694
Query: 350 VSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNP 409
YG G YF + A+ ++ +++ VLTG F +G + PPP +P
Sbjct: 695 PKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSP-GA 753
Query: 410 TDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 443
D DSV +N SP+ FV+F QA P+YL T T
Sbjct: 754 IDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCT 787
Score = 38.1 bits (87), Expect = 0.016
Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 17/125 (13%)
Query: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHR--- 126
I V D+ T VD +VN+ G++ A+++ G ++ E A+ +
Sbjct: 83 IELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSA 142
Query: 127 -DFIITPGGCLKCKIIIHVPGGK-----------DVRKTVTSVLEEC--EQRKYTSVSLP 172
+ +T G L CK IIH G + +++ + S+L + +V++P
Sbjct: 143 GEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIP 202
Query: 173 AIGTG 177
A+ +G
Sbjct: 203 ALSSG 207
>gi|226371714 poly (ADP-ribose) polymerase family, member 9 isoform
b [Homo sapiens]
Length = 819
Score = 85.1 bits (209), Expect = 1e-16
Identities = 67/196 (34%), Positives = 96/196 (48%), Gaps = 14/196 (7%)
Query: 52 VGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQ 111
+G + P F A M + +T Q+ G I + DVIVNS V+++IL+ AG
Sbjct: 266 LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGV 323
Query: 112 AVESE-CAVLAAQPHRD--FIITPGGCLKCKIIIHV------PGGKDVRKTVTSVLEECE 162
++SE A A Q R ++T G L CK I HV P + ++ + LE+C
Sbjct: 324 EMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCI 383
Query: 163 QRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQP--ELLN 220
++ TS+S PA+GTGN T A+ + D ++ F+ H L TVK VIF E+
Sbjct: 384 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQL-TVKFVIFPTDLEIYK 442
Query: 221 IFYDSMKKRDLSASLN 236
F M KR SLN
Sbjct: 443 AFSSEMAKRSKMLSLN 458
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Query: 290 KIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNA 349
K+E+I N L ++Q KK+ M+ K + LF V + GF R +
Sbjct: 635 KVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCD 694
Query: 350 VSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNP 409
YG G YF + A+ ++ +++ VLTG F +G + PPP +P
Sbjct: 695 PKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSP-GA 753
Query: 410 TDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 443
D DSV +N SP+ FV+F QA P+YL T T
Sbjct: 754 IDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCT 787
Score = 38.1 bits (87), Expect = 0.016
Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 17/125 (13%)
Query: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHR--- 126
I V D+ T VD +VN+ G++ A+++ G ++ E A+ +
Sbjct: 83 IELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSA 142
Query: 127 -DFIITPGGCLKCKIIIHVPGGK-----------DVRKTVTSVLEEC--EQRKYTSVSLP 172
+ +T G L CK IIH G + +++ + S+L + +V++P
Sbjct: 143 GEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIP 202
Query: 173 AIGTG 177
A+ +G
Sbjct: 203 ALSSG 207
>gi|226371712 poly (ADP-ribose) polymerase family, member 9 isoform
b [Homo sapiens]
Length = 819
Score = 85.1 bits (209), Expect = 1e-16
Identities = 67/196 (34%), Positives = 96/196 (48%), Gaps = 14/196 (7%)
Query: 52 VGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQ 111
+G + P F A M + +T Q+ G I + DVIVNS V+++IL+ AG
Sbjct: 266 LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGV 323
Query: 112 AVESE-CAVLAAQPHRD--FIITPGGCLKCKIIIHV------PGGKDVRKTVTSVLEECE 162
++SE A A Q R ++T G L CK I HV P + ++ + LE+C
Sbjct: 324 EMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCI 383
Query: 163 QRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQP--ELLN 220
++ TS+S PA+GTGN T A+ + D ++ F+ H L TVK VIF E+
Sbjct: 384 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQL-TVKFVIFPTDLEIYK 442
Query: 221 IFYDSMKKRDLSASLN 236
F M KR SLN
Sbjct: 443 AFSSEMAKRSKMLSLN 458
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Query: 290 KIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNA 349
K+E+I N L ++Q KK+ M+ K + LF V + GF R +
Sbjct: 635 KVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCD 694
Query: 350 VSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNP 409
YG G YF + A+ ++ +++ VLTG F +G + PPP +P
Sbjct: 695 PKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSP-GA 753
Query: 410 TDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 443
D DSV +N SP+ FV+F QA P+YL T T
Sbjct: 754 IDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCT 787
Score = 38.1 bits (87), Expect = 0.016
Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 17/125 (13%)
Query: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHR--- 126
I V D+ T VD +VN+ G++ A+++ G ++ E A+ +
Sbjct: 83 IELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSA 142
Query: 127 -DFIITPGGCLKCKIIIHVPGGK-----------DVRKTVTSVLEEC--EQRKYTSVSLP 172
+ +T G L CK IIH G + +++ + S+L + +V++P
Sbjct: 143 GEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIP 202
Query: 173 AIGTG 177
A+ +G
Sbjct: 203 ALSSG 207
>gi|226371710 poly (ADP-ribose) polymerase family, member 9 isoform
a [Homo sapiens]
Length = 854
Score = 85.1 bits (209), Expect = 1e-16
Identities = 67/196 (34%), Positives = 96/196 (48%), Gaps = 14/196 (7%)
Query: 52 VGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQ 111
+G + P F A M + +T Q+ G I + DVIVNS V+++IL+ AG
Sbjct: 301 LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGV 358
Query: 112 AVESE-CAVLAAQPHRD--FIITPGGCLKCKIIIHV------PGGKDVRKTVTSVLEECE 162
++SE A A Q R ++T G L CK I HV P + ++ + LE+C
Sbjct: 359 EMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCI 418
Query: 163 QRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQP--ELLN 220
++ TS+S PA+GTGN T A+ + D ++ F+ H L TVK VIF E+
Sbjct: 419 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQL-TVKFVIFPTDLEIYK 477
Query: 221 IFYDSMKKRDLSASLN 236
F M KR SLN
Sbjct: 478 AFSSEMAKRSKMLSLN 493
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Query: 290 KIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNA 349
K+E+I N L ++Q KK+ M+ K + LF V + GF R +
Sbjct: 670 KVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCD 729
Query: 350 VSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNP 409
YG G YF + A+ ++ +++ VLTG F +G + PPP +P
Sbjct: 730 PKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSP-GA 788
Query: 410 TDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 443
D DSV +N SP+ FV+F QA P+YL T T
Sbjct: 789 IDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCT 822
Score = 38.1 bits (87), Expect = 0.016
Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 17/125 (13%)
Query: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHR--- 126
I V D+ T VD +VN+ G++ A+++ G ++ E A+ +
Sbjct: 118 IELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSA 177
Query: 127 -DFIITPGGCLKCKIIIHVPGGK-----------DVRKTVTSVLEEC--EQRKYTSVSLP 172
+ +T G L CK IIH G + +++ + S+L + +V++P
Sbjct: 178 GEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIP 237
Query: 173 AIGTG 177
A+ +G
Sbjct: 238 ALSSG 242
>gi|226371706 poly (ADP-ribose) polymerase family, member 9 isoform
a [Homo sapiens]
Length = 854
Score = 85.1 bits (209), Expect = 1e-16
Identities = 67/196 (34%), Positives = 96/196 (48%), Gaps = 14/196 (7%)
Query: 52 VGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQ 111
+G + P F A M + +T Q+ G I + DVIVNS V+++IL+ AG
Sbjct: 301 LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGV 358
Query: 112 AVESE-CAVLAAQPHRD--FIITPGGCLKCKIIIHV------PGGKDVRKTVTSVLEECE 162
++SE A A Q R ++T G L CK I HV P + ++ + LE+C
Sbjct: 359 EMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCI 418
Query: 163 QRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQP--ELLN 220
++ TS+S PA+GTGN T A+ + D ++ F+ H L TVK VIF E+
Sbjct: 419 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQL-TVKFVIFPTDLEIYK 477
Query: 221 IFYDSMKKRDLSASLN 236
F M KR SLN
Sbjct: 478 AFSSEMAKRSKMLSLN 493
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Query: 290 KIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNA 349
K+E+I N L ++Q KK+ M+ K + LF V + GF R +
Sbjct: 670 KVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCD 729
Query: 350 VSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNP 409
YG G YF + A+ ++ +++ VLTG F +G + PPP +P
Sbjct: 730 PKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSP-GA 788
Query: 410 TDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 443
D DSV +N SP+ FV+F QA P+YL T T
Sbjct: 789 IDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCT 822
Score = 38.1 bits (87), Expect = 0.016
Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 17/125 (13%)
Query: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHR--- 126
I V D+ T VD +VN+ G++ A+++ G ++ E A+ +
Sbjct: 118 IELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSA 177
Query: 127 -DFIITPGGCLKCKIIIHVPGGK-----------DVRKTVTSVLEEC--EQRKYTSVSLP 172
+ +T G L CK IIH G + +++ + S+L + +V++P
Sbjct: 178 GEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIP 237
Query: 173 AIGTG 177
A+ +G
Sbjct: 238 ALSSG 242
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 67.0 bits (162), Expect = 3e-11
Identities = 57/208 (27%), Positives = 98/208 (47%), Gaps = 34/208 (16%)
Query: 262 MVQLEPGQSEYNTIKDKFTRTC-------------SSYAIEKIERIQNAFLWQSYQVKKR 308
++ L P E+ +++++ T + Y I KI+++ N LW+ Y +++
Sbjct: 955 LIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRK 1014
Query: 309 QMDIKNDHKNNERLLFHGTDADSVPYVN---QHGFNRSCAGKNAVSYGKGTYFAVDASYS 365
++ +N + NER+LFHG+ P+VN GF+ A + +G G YFA ++S S
Sbjct: 1015 EVSEENHNHANERMLFHGS-----PFVNAIIHKGFDERHAYIGGM-FGAGIYFAENSSKS 1068
Query: 366 AKDTYSKPDSNG-----RKHMYVV--RVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTN 418
+ Y G + Y+ ++L T G++ L K H+P SVT
Sbjct: 1069 NQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPG-HHSVTG 1127
Query: 419 ----NTRSPKLFVVFFDNQAYPEYLITF 442
N + +V++ QAYPEYLIT+
Sbjct: 1128 RPSVNGLALAEYVIYRGEQAYPEYLITY 1155
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 56.6 bits (135), Expect = 4e-08
Identities = 50/207 (24%), Positives = 96/207 (46%), Gaps = 32/207 (15%)
Query: 262 MVQLEPGQSEYNTIKDKFTRTC-------------SSYAIEKIERIQNAFLWQSYQVKKR 308
++ L P EY +++++ T + Y + +I+++ N L + + +++
Sbjct: 1108 LLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQK 1167
Query: 309 QMDIKNDHKNNERLLFHGTDADSVPYVN---QHGFNRSCAGKNAVSYGKGTYFAVDASYS 365
++ +N + +NER+LFHG+ P++N GF+ A + +G G YFA ++S S
Sbjct: 1168 EVSEENHNHHNERMLFHGS-----PFINAIIHKGFDERHAYIGGM-FGAGIYFAENSSKS 1221
Query: 366 AKDTYSKPDSNG-----RKHMYVV--RVLTGVFTKGRAGLVTPPPKNPHNPT---DLFDS 415
+ Y G + Y+ ++L T G++ L K H P +
Sbjct: 1222 NQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGR 1281
Query: 416 VTNNTRSPKLFVVFFDNQAYPEYLITF 442
+ N + +V++ QAYPEYLIT+
Sbjct: 1282 PSVNGLAYAEYVIYRGEQAYPEYLITY 1308
>gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens]
Length = 369
Score = 54.7 bits (130), Expect = 2e-07
Identities = 49/172 (28%), Positives = 75/172 (43%), Gaps = 16/172 (9%)
Query: 73 QVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI--- 129
QV DIA+ D +V+ T F V + + G+ E AVL + +
Sbjct: 198 QVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGK--EFVEAVLELRKKNGPLEVA 255
Query: 130 ---ITPGGCLKCKIIIHVPG---GKD-----VRKTVTSVLEECEQRKYTSVSLPAIGTGN 178
++ G L K +IH G D + KTV + L + +K S++ P+IG+G
Sbjct: 256 GAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGR 315
Query: 179 AGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRD 230
G T A I+ AI + + S+KTV V+F E + I+ M K D
Sbjct: 316 NGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLD 367
>gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens]
Length = 371
Score = 52.4 bits (124), Expect = 8e-07
Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 16/167 (9%)
Query: 78 DIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI------IT 131
++A +V+ I+N T + K + + + G+ E AVL + + ++
Sbjct: 205 NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGK--EFVEAVLELRKKNGPLEVAGAAVS 262
Query: 132 PGGCLKCKIIIHVPG---GKD-----VRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNP 183
G L K +IH G D + KTV + L + +K S++ P+IG+G G
Sbjct: 263 AGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPK 322
Query: 184 ITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRD 230
T A I+ AI + + S+KTV V+F E + I+ M K D
Sbjct: 323 QTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLD 369
>gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens]
Length = 371
Score = 52.4 bits (124), Expect = 8e-07
Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 16/167 (9%)
Query: 78 DIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI------IT 131
++A +V+ I+N T + K + + + G+ E AVL + + ++
Sbjct: 205 NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGK--EFVEAVLELRKKNGPLEVAGAAVS 262
Query: 132 PGGCLKCKIIIHVPG---GKD-----VRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNP 183
G L K +IH G D + KTV + L + +K S++ P+IG+G G
Sbjct: 263 AGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPK 322
Query: 184 ITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRD 230
T A I+ AI + + S+KTV V+F E + I+ M K D
Sbjct: 323 QTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLD 369
>gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens]
Length = 372
Score = 52.4 bits (124), Expect = 8e-07
Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 16/167 (9%)
Query: 78 DIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI------IT 131
++A +V+ I+N T + K + + + G+ E AVL + + ++
Sbjct: 206 NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGK--EFVEAVLELRKKNGPLEVAGAAVS 263
Query: 132 PGGCLKCKIIIHVPG---GKD-----VRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNP 183
G L K +IH G D + KTV + L + +K S++ P+IG+G G
Sbjct: 264 AGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPK 323
Query: 184 ITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRD 230
T A I+ AI + + S+KTV V+F E + I+ M K D
Sbjct: 324 QTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLD 370
>gi|13569840 MACRO domain containing 1 [Homo sapiens]
Length = 325
Score = 44.3 bits (103), Expect = 2e-04
Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 11/135 (8%)
Query: 78 DIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCLK 137
DI +VD IVN+ + GV I AG + EC L + IT G L
Sbjct: 160 DITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGPLLTDECRTLQSCKTGKAKITGGYRLP 219
Query: 138 CKIIIHVPG-----------GKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITV 186
K +IH G ++R S L+ + + SV+ P I TG G
Sbjct: 220 AKYVIHTVGPIAYGEPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPCEAA 279
Query: 187 ADNIIDAIVDFSSQH 201
A+ ++ + ++ QH
Sbjct: 280 AEIVLATLREWLEQH 294
>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform
b [Homo sapiens]
Length = 533
Score = 40.8 bits (94), Expect = 0.002
Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 13/159 (8%)
Query: 213 IFQPELLNIFYDSM---KKRDLSASLNFQSTFSMTTCNLPEHWTDMNHQLF-CMVQL-EP 267
I PELL D + +L+ +L S T +P H D ++QL C +QL +
Sbjct: 273 INSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEVP-HPLDRDYQLLKCQLQLLDS 331
Query: 268 GQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGT 327
G EY I+ +T S++ ++ I W+ Q + + N +LL+HGT
Sbjct: 332 GAPEYKVIQTYLEQTGSNHRCPTLQHI-----WKVNQEGEEDRFQAHSKLGNRKLLWHGT 386
Query: 328 DADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSA 366
+ V + G V GKG YFA + S SA
Sbjct: 387 NMAVVAAILTSGLRIMPHSGGRV--GKGIYFASENSKSA 423
>gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform
a [Homo sapiens]
Length = 540
Score = 40.8 bits (94), Expect = 0.002
Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 13/159 (8%)
Query: 213 IFQPELLNIFYDSM---KKRDLSASLNFQSTFSMTTCNLPEHWTDMNHQLF-CMVQL-EP 267
I PELL D + +L+ +L S T +P H D ++QL C +QL +
Sbjct: 280 INSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEVP-HPLDRDYQLLKCQLQLLDS 338
Query: 268 GQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGT 327
G EY I+ +T S++ ++ I W+ Q + + N +LL+HGT
Sbjct: 339 GAPEYKVIQTYLEQTGSNHRCPTLQHI-----WKVNQEGEEDRFQAHSKLGNRKLLWHGT 393
Query: 328 DADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSA 366
+ V + G V GKG YFA + S SA
Sbjct: 394 NMAVVAAILTSGLRIMPHSGGRV--GKGIYFASENSKSA 430
>gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens]
Length = 425
Score = 40.4 bits (93), Expect = 0.003
Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 11/115 (9%)
Query: 77 GDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCL 136
GDI +VD IVN+ + GV I AG + +EC L IT G L
Sbjct: 77 GDITLLEVDAIVNAANASLLGGGGVDGCIHRAAGPCLLAECRNLNGCDTGHAKITCGYDL 136
Query: 137 KCKIIIHVPG-----------GKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAG 180
K +IH G +D+ S L+ ++ SV+ P I TG G
Sbjct: 137 PAKYVIHTVGPIARGHINGSHKEDLANCYKSSLKLVKENNIRSVAFPCISTGIYG 191
>gi|207450721 ganglioside induced differentiation associated protein
2 isoform b [Homo sapiens]
Length = 496
Score = 31.6 bits (70), Expect = 1.5
Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 11/115 (9%)
Query: 77 GDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCL 136
GD+A IVN++ + K+ VS +I AG ++ + L + +T G L
Sbjct: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
Query: 137 KCKIIIHVPGGK-----------DVRKTVTSVLEECEQRKYTSVSLPAIGTGNAG 180
+ IIH G K + +VL+ +++ +SV I + G
Sbjct: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRG 175
>gi|8923143 ganglioside induced differentiation associated protein 2
isoform a [Homo sapiens]
Length = 497
Score = 31.6 bits (70), Expect = 1.5
Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 11/115 (9%)
Query: 77 GDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCL 136
GD+A IVN++ + K+ VS +I AG ++ + L + +T G L
Sbjct: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
Query: 137 KCKIIIHVPGGK-----------DVRKTVTSVLEECEQRKYTSVSLPAIGTGNAG 180
+ IIH G K + +VL+ +++ +SV I + G
Sbjct: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRG 175
>gi|4504993 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 28.9 bits (63), Expect = 9.8
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 10/80 (12%)
Query: 147 GKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHS--TP 204
G D + + C Q + TS+ +PA+ G+ + I+++ DF S S T
Sbjct: 76 GTDYEVCIENRSRSCYQLEKTSIKIPALSHGD--------YEITINSLHDFGSSTSKFTL 127
Query: 205 SLKTVKVVIFQPELLNIFYD 224
+ + V ++ PE+LN+ D
Sbjct: 128 NEQNVSLIPDTPEILNLSAD 147
>gi|189083786 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 28.9 bits (63), Expect = 9.8
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 10/80 (12%)
Query: 147 GKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHS--TP 204
G D + + C Q + TS+ +PA+ G+ + I+++ DF S S T
Sbjct: 76 GTDYEVCIENRSRSCYQLEKTSIKIPALSHGD--------YEITINSLHDFGSSTSKFTL 127
Query: 205 SLKTVKVVIFQPELLNIFYD 224
+ + V ++ PE+LN+ D
Sbjct: 128 NEQNVSLIPDTPEILNLSAD 147
>gi|239757103 PREDICTED: similar to fos39347_1 [Homo sapiens]
Length = 181
Score = 28.9 bits (63), Expect = 9.8
Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 3/38 (7%)
Query: 79 IATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESE 116
++++ D IV R R SG+ +A+L G GQ+ E+E
Sbjct: 22 VSSDDDDFIVK---REHTRASGIRKAVLSGPGQSAENE 56
>gi|239751609 PREDICTED: hypothetical protein XP_002347928 [Homo
sapiens]
Length = 120
Score = 28.9 bits (63), Expect = 9.8
Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 3/38 (7%)
Query: 79 IATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESE 116
++++ D IV R R SG+ +A+L G GQ+ E+E
Sbjct: 22 VSSDDDDFIVK---REHTRASGIRKAVLSGPGQSAENE 56
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,005,759
Number of Sequences: 37866
Number of extensions: 742965
Number of successful extensions: 1475
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1405
Number of HSP's gapped (non-prelim): 52
length of query: 444
length of database: 18,247,518
effective HSP length: 105
effective length of query: 339
effective length of database: 14,271,588
effective search space: 4838068332
effective search space used: 4838068332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.