Guide to the Human Genome
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Search of human proteins with 225735625

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225735625 disco-interacting protein 2A isoform e [Homo
sapiens]
         (1110 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens]   2218   0.0  
gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]    2147   0.0  
gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]   2133   0.0  
gi|44888818 DIP2 disco-interacting protein 2 homolog C [Homo sap...  1593   0.0  
gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens]    1572   0.0  
gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo sap...  1522   0.0  
gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens]    1499   0.0  
gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens]    1415   0.0  
gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]   1392   0.0  
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho...    43   0.001
gi|116284392 mucin 2 precursor [Homo sapiens]                          43   0.002
gi|153792110 HEG homolog 1 [Homo sapiens]                              42   0.002
gi|91982772 mucin 17 [Homo sapiens]                                    42   0.004
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                38   0.047
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                38   0.047
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                38   0.047
gi|20070107 orthodenticle homeobox 1 [Homo sapiens]                    38   0.047
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap...    38   0.061
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    37   0.079
gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ...    37   0.079
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]                     37   0.079
gi|20270323 zinc finger protein 653 [Homo sapiens]                     37   0.10 
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa...    37   0.14 
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap...    37   0.14 
gi|112421108 capicua homolog [Homo sapiens]                            37   0.14 
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]     36   0.18 
gi|83367077 mucin 16 [Homo sapiens]                                    36   0.23 
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca...    36   0.23 
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat...    36   0.23 
gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Hom...    36   0.23 

>gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens]
          Length = 1110

 Score = 2218 bits (5748), Expect = 0.0
 Identities = 1110/1110 (100%), Positives = 1110/1110 (100%)

Query: 1    MADRGCPLEAAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLV 60
            MADRGCPLEAAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLV
Sbjct: 1    MADRGCPLEAAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLV 60

Query: 61   HSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTS 120
            HSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTS
Sbjct: 61   HSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTS 120

Query: 121  SHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVAS 180
            SHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVAS
Sbjct: 121  SHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVAS 180

Query: 181  VRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQ 240
            VRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQ
Sbjct: 181  VRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQ 240

Query: 241  PDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYT 300
            PDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYT
Sbjct: 241  PDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYT 300

Query: 301  LTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELV 360
            LTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELV
Sbjct: 301  LTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELV 360

Query: 361  PVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWL 420
            PVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWL
Sbjct: 361  PVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWL 420

Query: 421  VIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACG 480
            VIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACG
Sbjct: 421  VIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACG 480

Query: 481  YSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAA 540
            YSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAA
Sbjct: 481  YSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAA 540

Query: 541  LVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVIC 600
            LVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVIC
Sbjct: 541  LVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVIC 600

Query: 601  PCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMP 660
            PCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMP
Sbjct: 601  PCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMP 660

Query: 661  GANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFD 720
            GANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFD
Sbjct: 661  GANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFD 720

Query: 721  RPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAV 780
            RPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAV
Sbjct: 721  RPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAV 780

Query: 781  FSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAP 840
            FSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAP
Sbjct: 781  FSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAP 840

Query: 841  LGGIHISETKQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRI 900
            LGGIHISETKQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRI
Sbjct: 841  LGGIHISETKQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRI 900

Query: 901  AQASGRELAHLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHK 960
            AQASGRELAHLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHK
Sbjct: 901  AQASGRELAHLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHK 960

Query: 961  RAERVAAALMEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTL 1020
            RAERVAAALMEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTL
Sbjct: 961  RAERVAAALMEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTL 1020

Query: 1021 PTVKMIVEVSKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPP 1080
            PTVKMIVEVSKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPP
Sbjct: 1021 PTVKMIVEVSKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPP 1080

Query: 1081 SPDVLAYLDFSVSTTGILAGVKAGRGGSRL 1110
            SPDVLAYLDFSVSTTGILAGVKAGRGGSRL
Sbjct: 1081 SPDVLAYLDFSVSTTGILAGVKAGRGGSRL 1110


>gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]
          Length = 1571

 Score = 2147 bits (5563), Expect = 0.0
 Identities = 1077/1093 (98%), Positives = 1080/1093 (98%), Gaps = 1/1093 (0%)

Query: 10   AAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 69
            AAP   + R + +  E     DVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP
Sbjct: 75   AAPKQQKSRPTASRDE-RFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 133

Query: 70   PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 129
            PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT
Sbjct: 134  PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 193

Query: 130  APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 189
            APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS
Sbjct: 194  APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 253

Query: 190  GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 249
            GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE
Sbjct: 254  GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 313

Query: 250  GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 309
            GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR
Sbjct: 314  GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 373

Query: 310  SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 369
            SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT
Sbjct: 374  SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 433

Query: 370  RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 429
            RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK
Sbjct: 434  RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 493

Query: 430  PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 489
            PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN
Sbjct: 494  PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 553

Query: 490  VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 549
            VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW
Sbjct: 554  VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 613

Query: 550  SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 609
            SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL
Sbjct: 614  SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 673

Query: 610  TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 669
            TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL
Sbjct: 674  TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 733

Query: 670  EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 729
            EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL
Sbjct: 734  EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 793

Query: 730  GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDD 789
            GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDD
Sbjct: 794  GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDD 853

Query: 790  RIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISET 849
            RIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISET
Sbjct: 854  RIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISET 913

Query: 850  KQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRIAQASGRELA 909
            KQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRIAQASGRELA
Sbjct: 914  KQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRIAQASGRELA 973

Query: 910  HLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAAL 969
            HLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAAL
Sbjct: 974  HLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAAL 1033

Query: 970  MEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEV 1029
            MEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEV
Sbjct: 1034 MEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEV 1093

Query: 1030 SKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPPSPDVLAYLD 1089
            SKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPPSPDVLAYLD
Sbjct: 1094 SKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPPSPDVLAYLD 1153

Query: 1090 FSVSTTGILAGVK 1102
            FSVSTTGILAGVK
Sbjct: 1154 FSVSTTGILAGVK 1166



 Score =  130 bits (328), Expect = 5e-30
 Identities = 170/669 (25%), Positives = 260/669 (38%), Gaps = 86/669 (12%)

Query: 241  PDPNQPKPEGSETSVLRGEPLTAGV------------------PRPPSLLATLQRWGT-T 281
            P P Q +PE    S++ G  L AG                    R    LA + +W   T
Sbjct: 939  PKPRQKQPEVGPASMIVGN-LVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHT 997

Query: 282  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 341
             P  P    L+  G    T T  +L  R+ ++A  L+ K        L  GD VALV+P 
Sbjct: 998  TPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEK------GRLSVGDHVALVYPP 1051

Query: 342  SDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFL-------ALTTD 394
               V  + AFYGCL    VPV +  P        Q +G  L +  + +        LTT 
Sbjct: 1052 G--VDLIAAFYGCLYCGCVPVTVRPP------HPQNLGTTLPTVKMIVEVSKSACVLTTQ 1103

Query: 395  ACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSK 454
            A  + L   +       + WP +  L  D     K    + P + D     AY+++  S 
Sbjct: 1104 AVTRLLRSKEAAAAVDIRTWPTI--LDTDDIPKKKIASVFRPPSPDV---LAYLDFSVST 1158

Query: 455  EGSTVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVV 514
             G   GV +SHA+  A CR++   C    +  +   LD     G     L SV +    V
Sbjct: 1159 TGILAGVKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSV 1218

Query: 515  SVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW---SLLAQRG---QRDVSLSSLRML 568
             VP   +++N   W+  V  YKAR        M      L AQ G    + V+LS +R  
Sbjct: 1219 LVPPLELESNVSLWLSAVSQYKARVTFCSYSVMEMCTKGLGAQTGVLRMKGVNLSCVRTC 1278

Query: 569  IVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAV 628
            +V     P  I+   +F  +F+  GL    +         + + ++      GP P    
Sbjct: 1279 MVVAEERP-RIALTQSFSKLFKDLGLPARAVSTTFGCRVNVAICLQ---GTAGPDPTTVY 1334

Query: 629  LSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSS 688
            + M  L +  +R+        L + + G+++PG  V +   E T        +GEI VSS
Sbjct: 1335 VDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTE-TKGPLGDSHLGEIWVSS 1393

Query: 689  SATGTAYYGLLG---ITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFI----------GPD 735
                T YY + G   +  + F A  ++ G        + RTG LGF+          G  
Sbjct: 1394 PHNATGYYTVYGEEALHADHFSA-RLSFGDTQTI---WARTGYLGFLRRTELTDASGGRH 1449

Query: 736  NLVFIVGKLD-GLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLV 794
            + +++VG LD  L + G+R H  D   +   A   +        AVF+ T L    +V+V
Sbjct: 1450 DALYVVGSLDETLELRGMRYHPIDIETSVIRAHRSI-----AECAVFTWTNL----LVVV 1500

Query: 795  AEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFL 854
             E   D  E+D+   ++ V   +   H + V  + +V    +P    G       +  FL
Sbjct: 1501 VEL--DGLEQDALDLVALVTNVVLEEHYLVVGVVVIVDPGVIPINSRGEKQRMHLRDGFL 1558

Query: 855  EGTLHPCNV 863
               L P  V
Sbjct: 1559 ADQLDPIYV 1567


>gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]
          Length = 1567

 Score = 2133 bits (5527), Expect = 0.0
 Identities = 1073/1093 (98%), Positives = 1076/1093 (98%), Gaps = 5/1093 (0%)

Query: 10   AAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 69
            AAP   + R + +  E     DVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP
Sbjct: 75   AAPKQQKSRPTASRDE-RFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 133

Query: 70   PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 129
            PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT
Sbjct: 134  PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 193

Query: 130  APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 189
            APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS
Sbjct: 194  APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 253

Query: 190  GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 249
            GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLE    DPNQPKPE
Sbjct: 254  GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLE----DPNQPKPE 309

Query: 250  GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 309
            GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR
Sbjct: 310  GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 369

Query: 310  SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 369
            SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT
Sbjct: 370  SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 429

Query: 370  RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 429
            RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK
Sbjct: 430  RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 489

Query: 430  PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 489
            PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN
Sbjct: 490  PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 549

Query: 490  VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 549
            VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW
Sbjct: 550  VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 609

Query: 550  SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 609
            SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL
Sbjct: 610  SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 669

Query: 610  TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 669
            TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL
Sbjct: 670  TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 729

Query: 670  EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 729
            EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL
Sbjct: 730  EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 789

Query: 730  GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDD 789
            GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDD
Sbjct: 790  GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDD 849

Query: 790  RIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISET 849
            RIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISET
Sbjct: 850  RIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISET 909

Query: 850  KQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRIAQASGRELA 909
            KQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRIAQASGRELA
Sbjct: 910  KQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRIAQASGRELA 969

Query: 910  HLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAAL 969
            HLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAAL
Sbjct: 970  HLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAAL 1029

Query: 970  MEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEV 1029
            MEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEV
Sbjct: 1030 MEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEV 1089

Query: 1030 SKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPPSPDVLAYLD 1089
            SKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPPSPDVLAYLD
Sbjct: 1090 SKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPPSPDVLAYLD 1149

Query: 1090 FSVSTTGILAGVK 1102
            FSVSTTGILAGVK
Sbjct: 1150 FSVSTTGILAGVK 1162



 Score =  130 bits (328), Expect = 5e-30
 Identities = 170/669 (25%), Positives = 260/669 (38%), Gaps = 86/669 (12%)

Query: 241  PDPNQPKPEGSETSVLRGEPLTAGV------------------PRPPSLLATLQRWGT-T 281
            P P Q +PE    S++ G  L AG                    R    LA + +W   T
Sbjct: 935  PKPRQKQPEVGPASMIVGN-LVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHT 993

Query: 282  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 341
             P  P    L+  G    T T  +L  R+ ++A  L+ K        L  GD VALV+P 
Sbjct: 994  TPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEK------GRLSVGDHVALVYPP 1047

Query: 342  SDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFL-------ALTTD 394
               V  + AFYGCL    VPV +  P        Q +G  L +  + +        LTT 
Sbjct: 1048 G--VDLIAAFYGCLYCGCVPVTVRPP------HPQNLGTTLPTVKMIVEVSKSACVLTTQ 1099

Query: 395  ACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSK 454
            A  + L   +       + WP +  L  D     K    + P + D     AY+++  S 
Sbjct: 1100 AVTRLLRSKEAAAAVDIRTWPTI--LDTDDIPKKKIASVFRPPSPDV---LAYLDFSVST 1154

Query: 455  EGSTVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVV 514
             G   GV +SHA+  A CR++   C    +  +   LD     G     L SV +    V
Sbjct: 1155 TGILAGVKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSV 1214

Query: 515  SVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW---SLLAQRG---QRDVSLSSLRML 568
             VP   +++N   W+  V  YKAR        M      L AQ G    + V+LS +R  
Sbjct: 1215 LVPPLELESNVSLWLSAVSQYKARVTFCSYSVMEMCTKGLGAQTGVLRMKGVNLSCVRTC 1274

Query: 569  IVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAV 628
            +V     P  I+   +F  +F+  GL    +         + + ++      GP P    
Sbjct: 1275 MVVAEERP-RIALTQSFSKLFKDLGLPARAVSTTFGCRVNVAICLQ---GTAGPDPTTVY 1330

Query: 629  LSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSS 688
            + M  L +  +R+        L + + G+++PG  V +   E T        +GEI VSS
Sbjct: 1331 VDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTE-TKGPLGDSHLGEIWVSS 1389

Query: 689  SATGTAYYGLLG---ITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFI----------GPD 735
                T YY + G   +  + F A  ++ G        + RTG LGF+          G  
Sbjct: 1390 PHNATGYYTVYGEEALHADHFSA-RLSFGDTQTI---WARTGYLGFLRRTELTDASGGRH 1445

Query: 736  NLVFIVGKLD-GLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLV 794
            + +++VG LD  L + G+R H  D   +   A   +        AVF+ T L    +V+V
Sbjct: 1446 DALYVVGSLDETLELRGMRYHPIDIETSVIRAHRSI-----AECAVFTWTNL----LVVV 1496

Query: 795  AEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFL 854
             E   D  E+D+   ++ V   +   H + V  + +V    +P    G       +  FL
Sbjct: 1497 VEL--DGLEQDALDLVALVTNVVLEEHYLVVGVVVIVDPGVIPINSRGEKQRMHLRDGFL 1554

Query: 855  EGTLHPCNV 863
               L P  V
Sbjct: 1555 ADQLDPIYV 1563


>gi|44888818 DIP2 disco-interacting protein 2 homolog C [Homo sapiens]
          Length = 1556

 Score = 1593 bits (4124), Expect = 0.0
 Identities = 774/1089 (71%), Positives = 909/1089 (83%), Gaps = 18/1089 (1%)

Query: 18   RESLAELELELSEDVHTEAVQAALAKYKERKM--PMPSKRRSVLVHSSVETYTPPDTSSA 75
            R S    +     DVHTEAVQAALAK+KERKM  PMPSKRRS++V +S++ YTPPDTSS 
Sbjct: 77   RRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSG 136

Query: 76   SEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAA 135
            SEDEGS++   + T T  Q   ++E W+ + I GS+TS              TT+ S+  
Sbjct: 137  SEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTS--------------TTSSSSTQ 182

Query: 136  TPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSY-FERPQVAS-VRSVPRGCSGSML 193
            + G+ A   LA + A THI+ HSAPPDVTT   EHS   ERPQ ++  R+ P+  +  ++
Sbjct: 183  SGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELM 242

Query: 194  ETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSET 253
            ET DGVPV+SRVS+KIQQL+NTLKRPKRPPL+EFFVDDFEELLEVQQPDPNQPKPEG++ 
Sbjct: 243  ETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQM 302

Query: 254  SVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKL 313
              +RGE L      PPSL A LQRWGT  PK+PCLT +DT GK +Y LTYGKLW+RS+K+
Sbjct: 303  LAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKV 362

Query: 314  AYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDA 373
            AY++L+KL +K EP+++PGDRVALVFPN+DP  FM AFYGCLLAE+VPVPIEVPLTRKDA
Sbjct: 363  AYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDA 422

Query: 374  GSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKD 433
            GSQQ+GFLLGSCGV +ALT+DAC KGLPK+ TGE+  FKGWP L W V + KHL+KPP+D
Sbjct: 423  GSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRD 482

Query: 434  WHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDF 493
            W P  +D    TAYIEYKT K+GS +GVTV+  +LL  C+ALTQACGY+EAET+ NVLDF
Sbjct: 483  WFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDF 542

Query: 494  KRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLA 553
            K+D GLWHG+LTSVMN MHV+S+PY+LMK NPLSWIQKVC YKA+ A VKSRDMHW+L+A
Sbjct: 543  KKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVA 602

Query: 554  QRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAI 613
             R QRD++LSSLRMLIVADGANPWSISSCDAFLNVFQS+GLR EVICPCASSPEALTVAI
Sbjct: 603  HRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAI 662

Query: 614  RRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTP 673
            RRP D    PP + VLSM+GL+YGVIRVD+EEKLSVLTVQDVG VMPGA +C VK +G P
Sbjct: 663  RRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVP 722

Query: 674  YLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIG 733
             LC+TDE+GE+CV + ATGT+YYGL G+TKN FE  P+T+ GAPI + PF RTGLLGF+G
Sbjct: 723  QLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVG 782

Query: 734  PDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVL 793
            P  LVF+VGK+DGLMV   RRHNADD+VATALAVEPMKFVYRGRIAVFSVTVLHD+RIV+
Sbjct: 783  PGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVI 842

Query: 794  VAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRF 853
            VAEQRPD++EEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPK PLGGIH+SETKQ F
Sbjct: 843  VAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLF 902

Query: 854  LEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRIAQASGRELAHLED 913
            LEG+LHPCNVLMCPHTCVTNLPKPRQKQPE+GPAS++VGNLV+GKRIAQASGR+L  +ED
Sbjct: 903  LEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIED 962

Query: 914  SDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEKG 973
            +DQARKFLFL++VLQWRA TTPDH L+ LLN +G + ++ TCVQLHKRAE++A  LME+G
Sbjct: 963  NDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERG 1022

Query: 974  RLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEVSKSA 1033
             L  GDHVALVYPPG+DLIAAFYGCLY GCVP+TVRPPHPQN+ TTLPTVKMIVEVS+SA
Sbjct: 1023 HLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSA 1082

Query: 1034 CVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPPSPDVLAYLDFSVS 1093
            C++TTQ + +LLRS+EAAAAVD+RTWP ILDTDD+PKK+ A + +P +PD LAYLDFSVS
Sbjct: 1083 CLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVS 1142

Query: 1094 TTGILAGVK 1102
            TTG+LAGVK
Sbjct: 1143 TTGMLAGVK 1151



 Score =  127 bits (319), Expect = 6e-29
 Identities = 159/664 (23%), Positives = 260/664 (39%), Gaps = 76/664 (11%)

Query: 241  PDPNQPKPEGSETSVLRGEPLTA-----------------GVPRPPSLLATLQRW-GTTQ 282
            P P Q +PE    SV+ G  ++                     R    L+ + +W   T 
Sbjct: 924  PKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTT 983

Query: 283  PKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNS 342
            P     T L+  G    +LT  +L  R+ K+A  L+ +        L+ GD VALV+P  
Sbjct: 984  PDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMER------GHLQDGDHVALVYPPG 1037

Query: 343  DPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGS-QQVGFLLGSCGVFLALTTDACQKGLP 401
              +  + AFYGCL A  VP+ +  P  +  A +   V  ++        +TT    K L 
Sbjct: 1038 --IDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLR 1095

Query: 402  KAQTGEVAAFKGWPPLSWLVIDGKHLAK--PPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 459
              +       + WP    L++D   L K  P +   P   DT    AY+++  S  G   
Sbjct: 1096 SREAAAAVDVRTWP----LILDTDDLPKKRPAQICKPCNPDT---LAYLDFSVSTTGMLA 1148

Query: 460  GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 519
            GV +SHA+  A CR++   C    +  +   LD     G     L SV +    + +P +
Sbjct: 1149 GVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPS 1208

Query: 520  LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVADG 573
             ++ NP  W+  V  YK R        M         Q      R + LS +R  +V   
Sbjct: 1209 ELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAE 1268

Query: 574  ANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNG 633
              P  I+   +F  +F+  GL P  +         L + ++      GP P    + M  
Sbjct: 1269 ERP-RIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ---GTSGPDPTTVYVDMRA 1324

Query: 634  LSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGT 693
            L +  +R+        L + + G+++PG  + +   E T        +GEI V S+   +
Sbjct: 1325 LRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE-TKGPLGDSHLGEIWVHSAHNAS 1383

Query: 694  AYYGLLG---ITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNL----------VFI 740
             Y+ + G   +  + F +  ++ G        + RTG LGF+    L          +++
Sbjct: 1384 GYFTIYGDESLQSDHFNS-RLSFGDTQTI---WARTGYLGFLRRTELTDANGERHDALYV 1439

Query: 741  VGKLDGLM-VTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRP 799
            VG LD  M + G+R H  D   +   A + +        AVF+ T L    +V+V E   
Sbjct: 1440 VGALDEAMELRGMRYHPIDIETSVIRAHKSVT-----ECAVFTWTNL----LVVVVEL-- 1488

Query: 800  DASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGTLH 859
            D SE+++   +  V   +   H + V  + +V    +P    G       +  FL   L 
Sbjct: 1489 DGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLD 1548

Query: 860  PCNV 863
            P  V
Sbjct: 1549 PIYV 1552


>gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens]
          Length = 889

 Score = 1572 bits (4070), Expect = 0.0
 Identities = 790/806 (98%), Positives = 793/806 (98%), Gaps = 1/806 (0%)

Query: 10  AAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 69
           AAP   + R + +  E     DVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP
Sbjct: 75  AAPKQQKSRPTASRDE-RFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 133

Query: 70  PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 129
           PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT
Sbjct: 134 PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 193

Query: 130 APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 189
           APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS
Sbjct: 194 APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 253

Query: 190 GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 249
           GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE
Sbjct: 254 GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 313

Query: 250 GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 309
           GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR
Sbjct: 314 GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 373

Query: 310 SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 369
           SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT
Sbjct: 374 SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 433

Query: 370 RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 429
           RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK
Sbjct: 434 RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 493

Query: 430 PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 489
           PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN
Sbjct: 494 PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 553

Query: 490 VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 549
           VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW
Sbjct: 554 VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 613

Query: 550 SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 609
           SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL
Sbjct: 614 SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 673

Query: 610 TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 669
           TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL
Sbjct: 674 TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 733

Query: 670 EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 729
           EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL
Sbjct: 734 EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 793

Query: 730 GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDD 789
           GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDD
Sbjct: 794 GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDD 853

Query: 790 RIVLVAEQRPDASEEDSFQWMSRVLQ 815
           RIVLVAEQRPDASEEDSFQWMSRVLQ
Sbjct: 854 RIVLVAEQRPDASEEDSFQWMSRVLQ 879



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 66/247 (26%), Positives = 93/247 (37%), Gaps = 46/247 (18%)

Query: 875  PKPRQKQPEVGPASMIVGN-LVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHT 933
            P P Q +PE    S++ G  L AG                    R    LA + +W   T
Sbjct: 305  PDPNQPKPEGSETSVLRGEPLTAGV------------------PRPPSLLATLQRWGT-T 345

Query: 934  TPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEK------GRLSVGDHVALVYPP 987
             P  P    L+  G    T T  +L  R+ ++A  L+ K        L  GD VALV+P 
Sbjct: 346  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 405

Query: 988  G--VDLIAAFYGCLYCGCVPVTVRPP------HPQNLGTTLPTVKMIVEVSKSACVLTTQ 1039
               V  + AFYGCL    VPV +  P        Q +G  L +  + +        LTT 
Sbjct: 406  SDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFL-------ALTTD 458

Query: 1040 AVTRLLRSKEAAAAVDIRTWPTI--LDTDDIPKKKIASVFRPPSPDV---LAYLDFSVST 1094
            A  + L   +       + WP +  L  D     K    + P + D     AY+++  S 
Sbjct: 459  ACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSK 518

Query: 1095 TGILAGV 1101
             G   GV
Sbjct: 519  EGSTVGV 525


>gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo sapiens]
          Length = 1576

 Score = 1522 bits (3941), Expect = 0.0
 Identities = 740/1083 (68%), Positives = 890/1083 (82%), Gaps = 24/1083 (2%)

Query: 31   DVHTEAVQAALAKYKERKM--PMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRL 88
            D+HTEAVQAALAK+KE+KM  PMP+KRRS  V S  +  TPPDTSSASEDEGSLRR   L
Sbjct: 101  DIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAAL 160

Query: 89   TSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGL 148
            ++   QS  + E W++R IQGSSTSSSASST SH   + T+              +LA +
Sbjct: 161  SAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSG-------------SLADV 207

Query: 149  EAHTHIDLHSAPPDVTT--------GLVEHSYFERPQVASVRSVPRGCS-GSMLETADGV 199
             A+T I+  SAPPDVTT          +  +  + P    V+ + +G +  S+++TADGV
Sbjct: 208  FANTRIENFSAPPDVTTTTSSSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGV 267

Query: 200  PVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGE 259
            PV+SRVS+KIQQLLNTLKRPKRPPLKEFFVDD EE++EV QPDPNQPKPEG + + ++GE
Sbjct: 268  PVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGE 327

Query: 260  PLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLN 319
            PL      PP+L + LQRWGTTQ K  CLTALD TGK VYTLTYGKLWSRSLKLAYTLLN
Sbjct: 328  PLGVICNWPPALESALQRWGTTQAKCSCLTALDMTGKPVYTLTYGKLWSRSLKLAYTLLN 387

Query: 320  KLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVG 379
            KL +KNEP+LKPGDRVALV+PN+DPVMFMVAFYGCLLAE++PVPIEVPLTRKDAG QQ+G
Sbjct: 388  KLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIG 447

Query: 380  FLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQ 439
            FLLGSCG+ LALT++ C KGLPK Q GE+  FKGWP L W+V D K+L+KPPKDW P   
Sbjct: 448  FLLGSCGIALALTSEVCLKGLPKTQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQPHIS 507

Query: 440  DTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGL 499
              GT  AYIEYKTSKEGS +GVTVS  ++L+ C+AL+QAC YSE ET+ NVLDFK+DAGL
Sbjct: 508  PAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHCQALSQACNYSEGETIVNVLDFKKDAGL 567

Query: 500  WHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQRD 559
            WHG+  +VMN+MH +SVPY++MK  PLSW+Q+V  +KA+ ALVK RD+HW+++A R QRD
Sbjct: 568  WHGMFANVMNKMHTISVPYSVMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRD 627

Query: 560  VSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDL 619
            VSLSSLRMLIV DGANPWS+SSCDAFL++FQS GL+PE ICPCA+S EA+TVAIRRP   
Sbjct: 628  VSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVP 687

Query: 620  GGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTD 679
            G P P +A+LSMNGLSYGVIRV+TE+K S LTVQDVG VMPG  +C+VK +G P LCKTD
Sbjct: 688  GAPLPGRAILSMNGLSYGVIRVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGPPQLCKTD 747

Query: 680  EVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNLVF 739
            E+GEICVSS   G  Y+GL G+TKN FE +PV + G+P+ D PF R+GLLGF+GP +LVF
Sbjct: 748  EIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVNSAGSPVGDVPFIRSGLLGFVGPGSLVF 807

Query: 740  IVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRP 799
            +VGK+DGL++   RRHNADD+VAT LAVE +K VYRGRIAVFSV+V +D+RIV+VAEQRP
Sbjct: 808  VVGKMDGLLMVSGRRHNADDIVATGLAVESIKTVYRGRIAVFSVSVFYDERIVVVAEQRP 867

Query: 800  DASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGTLH 859
            DASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPK PLGGIHIS+TKQ FLEG+LH
Sbjct: 868  DASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHISQTKQLFLEGSLH 927

Query: 860  PCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRIAQASGRELAHLEDSDQARK 919
            PCN+LMCPHTCVTNLPKPRQKQP VGPAS++VGNLVAGKRIAQA+GR+L  +E++D  RK
Sbjct: 928  PCNILMCPHTCVTNLPKPRQKQPGVGPASVMVGNLVAGKRIAQAAGRDLGQIEENDLVRK 987

Query: 920  FLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEKGRLSVGD 979
              FLA++LQWRA  TPDH LF+LLNAKGT   TA+C+QLHKRAER+A+ L +KG L+ GD
Sbjct: 988  HQFLAEILQWRAQATPDHVLFMLLNAKGTTVCTASCLQLHKRAERIASVLGDKGHLNAGD 1047

Query: 980  HVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEVSKSACVLTTQ 1039
            +V L+YPPG++LIAAFYGCLY GC+PVTVRPPH QNL  TLPTV+MIV+VSK+AC+LT+Q
Sbjct: 1048 NVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQ 1107

Query: 1040 AVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPPSPDVLAYLDFSVSTTGILA 1099
             + RLLRS+EAAAAVD++TWPTI+DTDD+P+K++  +++PP+P++LAYLDFSVSTTG+L 
Sbjct: 1108 TLMRLLRSREAAAAVDVKTWPTIIDTDDLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLT 1167

Query: 1100 GVK 1102
            GVK
Sbjct: 1168 GVK 1170



 Score =  115 bits (287), Expect = 3e-25
 Identities = 153/662 (23%), Positives = 249/662 (37%), Gaps = 71/662 (10%)

Query: 241  PDPNQPKPEGSETSVLRGEPLTAG------------------VPRPPSLLATLQRW-GTT 281
            P P Q +P     SV+ G  L AG                  + R    LA + +W    
Sbjct: 943  PKPRQKQPGVGPASVMVGN-LVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQA 1001

Query: 282  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 341
             P       L+  G  V T +  +L  R+ ++A  L +K        L  GD V L++P 
Sbjct: 1002 TPDHVLFMLLNAKGTTVCTASCLQLHKRAERIASVLGDK------GHLNAGDNVVLLYPP 1055

Query: 342  SDPVMFMVAFYGCLLAELVPVPIEVPLTRK-DAGSQQVGFLLGSCGVFLALTTDACQKGL 400
               +  + AFYGCL A  +PV +  P  +   A    V  ++        LT+    + L
Sbjct: 1056 G--IELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLL 1113

Query: 401  PKAQTGEVAAFKGWPPLSWLVIDGKHLAKP--PKDWHPLAQDTGTGTAYIEYKTSKEGST 458
               +       K WP     +ID   L +   P+ + P    T    AY+++  S  G  
Sbjct: 1114 RSREAAAAVDVKTWPT----IIDTDDLPRKRLPQLYKP---PTPEMLAYLDFSVSTTGML 1166

Query: 459  VGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPY 518
             GV +SH+++ A CRA+   C    +  +   LD     G     L SV +    V +P 
Sbjct: 1167 TGVKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPP 1226

Query: 519  ALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVAD 572
              ++ N   W+  V  YK R        M         Q      R ++LS +R  +V  
Sbjct: 1227 MELENNLFLWLSTVNQYKIRDTFCSYSVMELCTKGLGNQVEVLKTRGINLSCVRTCVVVA 1286

Query: 573  GANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMN 632
               P  ++   +F  +F+  GL P  +     S   + + ++      GP P    + + 
Sbjct: 1287 EERP-RVALQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQ---GTSGPDPTTVYVDLK 1342

Query: 633  GLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATG 692
             L +  +R+        L + + G+++PG  V +V  E T        +GEI V+S  T 
Sbjct: 1343 SLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE-TKGPVGDSHLGEIWVNSPHTA 1401

Query: 693  TAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNL----------VFIVG 742
            + YY +        +               + RTG LGF+    L          +++VG
Sbjct: 1402 SGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAATGERHDALYVVG 1461

Query: 743  KLD-GLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRPDA 801
             LD  L + G+R H  D   + +     +        AVF+ T L    +V+V E     
Sbjct: 1462 ALDETLELRGLRYHPIDIETSVSRIHRSI-----AECAVFTWTNL----LVVVVEL--CG 1510

Query: 802  SEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGTLHPC 861
            SE+++   +  V   +   H + V  + +V    +P    G       +  FL   L P 
Sbjct: 1511 SEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQRMHLRDSFLADQLDPI 1570

Query: 862  NV 863
             V
Sbjct: 1571 YV 1572


>gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens]
          Length = 841

 Score = 1499 bits (3881), Expect = 0.0
 Identities = 752/768 (97%), Positives = 755/768 (98%), Gaps = 1/768 (0%)

Query: 10  AAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 69
           AAP   + R + +  E     DVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP
Sbjct: 75  AAPKQQKSRPTASRDE-RFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 133

Query: 70  PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 129
           PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT
Sbjct: 134 PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 193

Query: 130 APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 189
           APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS
Sbjct: 194 APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 253

Query: 190 GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 249
           GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE
Sbjct: 254 GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 313

Query: 250 GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 309
           GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR
Sbjct: 314 GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 373

Query: 310 SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 369
           SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT
Sbjct: 374 SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 433

Query: 370 RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 429
           RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK
Sbjct: 434 RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 493

Query: 430 PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 489
           PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN
Sbjct: 494 PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 553

Query: 490 VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 549
           VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW
Sbjct: 554 VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 613

Query: 550 SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 609
           SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL
Sbjct: 614 SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 673

Query: 610 TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 669
           TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL
Sbjct: 674 TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 733

Query: 670 EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 729
           EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL
Sbjct: 734 EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 793

Query: 730 GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGR 777
           GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGR
Sbjct: 794 GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGR 841



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 66/247 (26%), Positives = 93/247 (37%), Gaps = 46/247 (18%)

Query: 875  PKPRQKQPEVGPASMIVGN-LVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHT 933
            P P Q +PE    S++ G  L AG                    R    LA + +W   T
Sbjct: 305  PDPNQPKPEGSETSVLRGEPLTAGV------------------PRPPSLLATLQRWGT-T 345

Query: 934  TPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEK------GRLSVGDHVALVYPP 987
             P  P    L+  G    T T  +L  R+ ++A  L+ K        L  GD VALV+P 
Sbjct: 346  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 405

Query: 988  G--VDLIAAFYGCLYCGCVPVTVRPP------HPQNLGTTLPTVKMIVEVSKSACVLTTQ 1039
               V  + AFYGCL    VPV +  P        Q +G  L +  + +        LTT 
Sbjct: 406  SDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFL-------ALTTD 458

Query: 1040 AVTRLLRSKEAAAAVDIRTWPTI--LDTDDIPKKKIASVFRPPSPDV---LAYLDFSVST 1094
            A  + L   +       + WP +  L  D     K    + P + D     AY+++  S 
Sbjct: 459  ACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSK 518

Query: 1095 TGILAGV 1101
             G   GV
Sbjct: 519  EGSTVGV 525


>gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens]
          Length = 812

 Score = 1415 bits (3664), Expect = 0.0
 Identities = 709/725 (97%), Positives = 712/725 (98%), Gaps = 1/725 (0%)

Query: 10  AAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 69
           AAP   + R + +  E     DVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP
Sbjct: 75  AAPKQQKSRPTASRDE-RFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 133

Query: 70  PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 129
           PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT
Sbjct: 134 PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 193

Query: 130 APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 189
           APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS
Sbjct: 194 APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 253

Query: 190 GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 249
           GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE
Sbjct: 254 GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 313

Query: 250 GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 309
           GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR
Sbjct: 314 GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 373

Query: 310 SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 369
           SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT
Sbjct: 374 SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 433

Query: 370 RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 429
           RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK
Sbjct: 434 RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 493

Query: 430 PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 489
           PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN
Sbjct: 494 PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 553

Query: 490 VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 549
           VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW
Sbjct: 554 VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 613

Query: 550 SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 609
           SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL
Sbjct: 614 SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 673

Query: 610 TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 669
           TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL
Sbjct: 674 TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 733

Query: 670 EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 729
           EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL
Sbjct: 734 EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 793

Query: 730 GFIGP 734
           GFIGP
Sbjct: 794 GFIGP 798



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 66/247 (26%), Positives = 93/247 (37%), Gaps = 46/247 (18%)

Query: 875  PKPRQKQPEVGPASMIVGN-LVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHT 933
            P P Q +PE    S++ G  L AG                    R    LA + +W   T
Sbjct: 305  PDPNQPKPEGSETSVLRGEPLTAGV------------------PRPPSLLATLQRWGT-T 345

Query: 934  TPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEK------GRLSVGDHVALVYPP 987
             P  P    L+  G    T T  +L  R+ ++A  L+ K        L  GD VALV+P 
Sbjct: 346  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 405

Query: 988  G--VDLIAAFYGCLYCGCVPVTVRPP------HPQNLGTTLPTVKMIVEVSKSACVLTTQ 1039
               V  + AFYGCL    VPV +  P        Q +G  L +  + +        LTT 
Sbjct: 406  SDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFL-------ALTTD 458

Query: 1040 AVTRLLRSKEAAAAVDIRTWPTI--LDTDDIPKKKIASVFRPPSPDV---LAYLDFSVST 1094
            A  + L   +       + WP +  L  D     K    + P + D     AY+++  S 
Sbjct: 459  ACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSK 518

Query: 1095 TGILAGV 1101
             G   GV
Sbjct: 519  EGSTVGV 525


>gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]
          Length = 798

 Score = 1392 bits (3602), Expect = 0.0
 Identities = 709/768 (92%), Positives = 712/768 (92%), Gaps = 44/768 (5%)

Query: 10  AAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 69
           AAP   + R + +  E     DVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP
Sbjct: 75  AAPKQQKSRPTASRDE-RFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 133

Query: 70  PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 129
           PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT
Sbjct: 134 PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 193

Query: 130 APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 189
           APSAAATPGAAATTALAGLEAHTHI                                   
Sbjct: 194 APSAAATPGAAATTALAGLEAHTHI----------------------------------- 218

Query: 190 GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 249
                   GVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE
Sbjct: 219 --------GVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 270

Query: 250 GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 309
           GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR
Sbjct: 271 GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 330

Query: 310 SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 369
           SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT
Sbjct: 331 SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 390

Query: 370 RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 429
           RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK
Sbjct: 391 RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 450

Query: 430 PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 489
           PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN
Sbjct: 451 PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 510

Query: 490 VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 549
           VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW
Sbjct: 511 VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 570

Query: 550 SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 609
           SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL
Sbjct: 571 SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 630

Query: 610 TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 669
           TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL
Sbjct: 631 TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 690

Query: 670 EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 729
           EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL
Sbjct: 691 EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 750

Query: 730 GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGR 777
           GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGR
Sbjct: 751 GFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGR 798



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 66/247 (26%), Positives = 93/247 (37%), Gaps = 46/247 (18%)

Query: 875  PKPRQKQPEVGPASMIVGN-LVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHT 933
            P P Q +PE    S++ G  L AG                    R    LA + +W   T
Sbjct: 262  PDPNQPKPEGSETSVLRGEPLTAGV------------------PRPPSLLATLQRWGT-T 302

Query: 934  TPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEK------GRLSVGDHVALVYPP 987
             P  P    L+  G    T T  +L  R+ ++A  L+ K        L  GD VALV+P 
Sbjct: 303  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 362

Query: 988  G--VDLIAAFYGCLYCGCVPVTVRPP------HPQNLGTTLPTVKMIVEVSKSACVLTTQ 1039
               V  + AFYGCL    VPV +  P        Q +G  L +  + +        LTT 
Sbjct: 363  SDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFL-------ALTTD 415

Query: 1040 AVTRLLRSKEAAAAVDIRTWPTI--LDTDDIPKKKIASVFRPPSPDV---LAYLDFSVST 1094
            A  + L   +       + WP +  L  D     K    + P + D     AY+++  S 
Sbjct: 416  ACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSK 475

Query: 1095 TGILAGV 1101
             G   GV
Sbjct: 476  EGSTVGV 482


>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
            sapiens]
          Length = 480

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 54/200 (27%), Positives = 87/200 (43%), Gaps = 34/200 (17%)

Query: 917  ARKFLFLADVLQWRAHTTPD-----HPLFLLLNAKGTVT--STATCVQLHKRAERVAAAL 969
            ++ F F  DVL   +    D     +P    ++AKG     S     QL K+A   A+ L
Sbjct: 46   SQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKA---ASIL 102

Query: 970  MEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEV 1029
             +   LS GD + ++ PP  +   A++ CL C  + +T  P  PQ    T   ++  + +
Sbjct: 103  SDTCALSHGDRLMIILPPTPE---AYWICLACVRLGITFVPGSPQ---LTAKKIRYQLRM 156

Query: 1030 SKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDD------IPKKKIASV------- 1076
            SK+ C++  +A+  ++ S    A  D  T  T L   D      +  KK+  V       
Sbjct: 157  SKAQCIVANEAMAPVVNS----AVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTY 212

Query: 1077 FRPPSPDVLAYLDFSVSTTG 1096
             R  S D +A + F+  TTG
Sbjct: 213  MRTKSQDPMA-IFFTKGTTG 231


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 54/239 (22%), Positives = 87/239 (36%), Gaps = 44/239 (18%)

Query: 63   SVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSH 122
            ++ T TPP T++ S        P   T+TP  + +   P    +   +ST++   +T+  
Sbjct: 1590 TITTTTPPPTTTPSP-------PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1642

Query: 123  PGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVR 182
            P    TT P    TP    TT  +       I   + PP  TT             + + 
Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPS-----PPITTTTTPPPTTT-----------PSSPIT 1686

Query: 183  SVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPD 242
            + P   + +M   +     +S +++       T   P  PP              +  P 
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP--PPTT------------MTTPS 1732

Query: 243  PNQ-PKPEGSETSVL----RGEPLTAGVPRPPSLLA-TLQRWGTTQPKSPCLTALDTTG 295
            P   P P  +  + L       PLT   P PPS+   T   + TT P +PC+   + TG
Sbjct: 1733 PTTTPSPPTTTMTTLPPTTTSSPLTT-TPLPPSITPPTFSPFSTTTPTTPCVPLCNWTG 1790



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 51/231 (22%), Positives = 75/231 (32%), Gaps = 17/231 (7%)

Query: 66   TYTP-PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPG 124
            T TP P T++ S    +   P   T+TP  + +   P    +   +ST++   +T+  P 
Sbjct: 1467 TTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPP 1526

Query: 125  GRPTTAPSAAATPGAAATTALAGLEAHTHI--DLHSAPPDVTTGLVEHSYFERPQVASVR 182
               TT P    TP    TT +    + T +      +PP  TT     +    P   +  
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1586

Query: 183  SVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPD 242
            S P   + +   T    P  +           T   P   P                 P 
Sbjct: 1587 SPPTITTTTPPPTTTPSPPTT---------TTTTPPPTTTPSPPTTTPITPPTSTTTLPP 1637

Query: 243  PNQPKPEGSETS----VLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLT 289
               P P  + T+         P T   P PP +  T     TT P SP  T
Sbjct: 1638 TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP-ITTTTTPPPTTTPSSPITT 1687



 Score = 30.4 bits (67), Expect = 9.7
 Identities = 27/108 (25%), Positives = 43/108 (39%), Gaps = 4/108 (3%)

Query: 62   SSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSS 121
            +  +T  P  TS+A   E +   P   +STP  S S+  P  +     S+   +   TS+
Sbjct: 4191 TGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTST 4250

Query: 122  HPGGRP----TTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTT 165
             P   P    TT+     +P  + TT+  G          S+ P  +T
Sbjct: 4251 APPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPST 4298


>gi|153792110 HEG homolog 1 [Homo sapiens]
          Length = 1381

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 58/253 (22%), Positives = 94/253 (37%), Gaps = 38/253 (15%)

Query: 27  ELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPG 86
           E S   H +  ++ ++ Y + +   PS    VL  S++ +YTP           ++  P 
Sbjct: 597 EYSSFFHAQTERSNISSY-DGEYAQPSTESPVLHTSNLPSYTP-----------TINMPN 644

Query: 87  RLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAAT--------PG 138
             TS  L +        D      S+SSS+SS+SS   G P   PS + +        P 
Sbjct: 645 --TSVVLDT--------DAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS 694

Query: 139 AAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCSGSMLETADG 198
             A+  L    +       S+P  +   L   +    P   S  ++P+  S  +L  A  
Sbjct: 695 TRASVHLLKSTSDASTPWSSSPSPLPVSLTTST--SAPLSVSQTTLPQSSSTPVLPRARE 752

Query: 199 VPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRG 258
            PV S  +S +   +  L   +   LK       E+++   +       P  S  +V   
Sbjct: 753 TPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTN 812

Query: 259 EPLTAGVPRPPSL 271
            PL      PPSL
Sbjct: 813 SPL------PPSL 819


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 47/220 (21%), Positives = 84/220 (38%), Gaps = 20/220 (9%)

Query: 7    PLEAAPLPAEVRESLAELELELSEDVHTEA-VQAALAKYKERKMPMPSKRRSVLVHSSVE 65
            P+   P+      +L+   ++ +  V T   V ++    +   MP+ +        + V 
Sbjct: 3052 PVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVP 3111

Query: 66   TYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGG 125
              T P TSSA            L++TP+ + + V          +ST + +S T+S    
Sbjct: 3112 VSTTPVTSSAIST---------LSTTPVDTSTPVT---------TSTEAHSSPTTSEGTS 3153

Query: 126  RPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVP 185
             PT+ PS  +TP      +   + +     L + P D +T +   +       A   S+P
Sbjct: 3154 MPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIP 3213

Query: 186  RGCSGSMLETADGVPV-NSRVSSKIQQLLNTLKRPKRPPL 224
                   +     VPV N+ V+S    +L+T       PL
Sbjct: 3214 TSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPL 3253



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 49/211 (23%), Positives = 88/211 (41%), Gaps = 31/211 (14%)

Query: 4    RGCPLEAAPLPAEVRESLAELELELSEDVHTEA-VQAALAKYKERKMPMPSKRRSVLVHS 62
            R  P+   PL +    +L+   ++ S  V T     ++    K+  MP+ +        +
Sbjct: 2577 RSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLT 2636

Query: 63   SVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSH 122
            S+   T P  SS +           L++TP+ +         R +  +ST +S+S T++ 
Sbjct: 2637 SILVSTMPVASSEAST---------LSTTPVDT---------RTLVTTSTGTSSSPTTAE 2678

Query: 123  PGGRPTTAPSAAATPGA---AATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVA 179
                PT+ P   +TP      +TT LA  EA T   L + P D +T +   +     + +
Sbjct: 2679 GSSMPTSTPGERSTPLTNILVSTTLLANSEAST---LSTTPVDTSTPVTTSA-----EAS 2730

Query: 180  SVRSVPRGCSGSMLETADG-VPVNSRVSSKI 209
            S  +   G S  +   +DG  P+ S + S +
Sbjct: 2731 SSPTTAEGTSMRISTPSDGSTPLTSILVSTL 2761



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 51/192 (26%), Positives = 81/192 (42%), Gaps = 29/192 (15%)

Query: 50   PMPSKRRSVLVHSSVETYTPPDTSS----------------ASEDEGSLRRPGR-LTSTP 92
            P+ S   S L  + V+T TP  TS+                +S  EG+       +++TP
Sbjct: 3351 PVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTP 3410

Query: 93   LQSHS----SVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGA---AATTAL 145
            + S      S  P     +  +ST +S+S T +     PT+  S  +TP +    +TT +
Sbjct: 3411 VVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPV 3470

Query: 146  AGLEAHTHIDLHSAPPDVTTGLVEHS-YFERPQVASVRSVPRGCSGSMLETADGVPVNSR 204
            A  EA T   L + P D +T +   S     P  A V S+P   +G        +PV++ 
Sbjct: 3471 ASSEAST---LSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTT 3527

Query: 205  -VSSKIQQLLNT 215
             V+S     L+T
Sbjct: 3528 PVASSEASTLST 3539



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 57/217 (26%), Positives = 88/217 (40%), Gaps = 32/217 (14%)

Query: 8    LEAAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKE-RKMPM--PSKRRSVLVHSSV 64
            +   P+      +L+   ++    V T A  ++     E   MP+  P +RR+ L   SV
Sbjct: 2935 VSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSV 2994

Query: 65   ETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPG 124
             T        AS +  +L R    TSTP+ +               ST +S+S T++   
Sbjct: 2995 STMPV-----ASSEASTLSRTPADTSTPVTT---------------STEASSSPTTAEGT 3034

Query: 125  GRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTTGLVEHS-YFERPQVAS 180
            G P + PS  +TP  +   +TT +A  EA T   L + P D  + +V  +     P  A 
Sbjct: 3035 GIPISTPSEGSTPLTSIPVSTTPVAIPEAST---LSTTPVDSNSPVVTSTEVSSSPTPAE 3091

Query: 181  VRSVPRGCSGSMLETADGVPVNSR--VSSKIQQLLNT 215
              S+P            GVPV++    SS I  L  T
Sbjct: 3092 GTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTT 3128



 Score = 38.5 bits (88), Expect = 0.036
 Identities = 39/165 (23%), Positives = 71/165 (43%), Gaps = 26/165 (15%)

Query: 50  PMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQG 109
           P  ++  S+   +  E  TP  +   S    +      L++TP+ S + V          
Sbjct: 434 PTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVT--------- 484

Query: 110 SSTSSSASSTSSHPGGRPTTAPSAAATP---GAAATTALAGLEAHTHIDLHSAPPDVTTG 166
           +ST +S+S  ++     PT+ PS  +TP    + +T  +A  EA T   L + P D +T 
Sbjct: 485 TSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAST---LSTTPVDTSTP 541

Query: 167 LVEHSYFERPQVASVRSVPRGCSGSMLETADG------VPVNSRV 205
           +   S     + +S  + P G S      ++G      +PV++R+
Sbjct: 542 VTTSS-----EASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRL 581



 Score = 38.5 bits (88), Expect = 0.036
 Identities = 47/172 (27%), Positives = 72/172 (41%), Gaps = 23/172 (13%)

Query: 64   VETYTPPDTSSASEDEGSL------RRPGRLTSTPLQ---------SHSSVEPWLDRVIQ 108
            V TY+   +SS + D  S+           LTS P+          S  S  P    +  
Sbjct: 1073 VTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPV 1132

Query: 109  GSSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTT 165
             +ST +S+S T++     PT+ PS   TP A+   +TT +   EA+T   L + P D  T
Sbjct: 1133 TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANT---LSTTPVDSKT 1189

Query: 166  GLVEHSYFER-PQVASVRSVPRGCSGSMLETADGVPV-NSRVSSKIQQLLNT 215
             +   +     P  A V S+P    G        +PV ++ V+S     L+T
Sbjct: 1190 QVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLST 1241



 Score = 37.4 bits (85), Expect = 0.079
 Identities = 54/268 (20%), Positives = 95/268 (35%), Gaps = 33/268 (12%)

Query: 7    PLEAAPLPAEVRESLAELELELSEDVHTEAVQA---ALAKYKERKMPMPSKRRSVLVHSS 63
            P E +PL   +  S+  +    +  + T  V +        +    P P++  S+   + 
Sbjct: 801  PSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTY 860

Query: 64   VETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHP 123
             E  TP  +   S    +      L++TP+ + + V          +ST + +S T+S  
Sbjct: 861  SEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVT---------NSTEARSSPTTSEG 911

Query: 124  GGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTTGLVEHS-YFERPQVA 179
               PT+ P   +TP  +   +TT +   EA T   L + P D +T +   +     P  A
Sbjct: 912  TSMPTSTPGEGSTPLTSMPDSTTPVVSSEART---LSATPVDTSTPVTTSTEATSSPTTA 968

Query: 180  SVRSVPRGCSGSMLETADGVPV-NSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEV 238
               S+P              PV ++ V++     L+T       PL              
Sbjct: 969  EGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPL-------------T 1015

Query: 239  QQPDPNQPKPEGSETSVLRGEPLTAGVP 266
               + + P P    TS+    P     P
Sbjct: 1016 TSTEASSPPPTAEGTSMPTSTPSEGSTP 1043



 Score = 37.4 bits (85), Expect = 0.079
 Identities = 39/156 (25%), Positives = 68/156 (43%), Gaps = 27/156 (17%)

Query: 34   TEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPL 93
            TEA  +  A+        PS+  + L      T  P   +  +  E S+     L++TP+
Sbjct: 3199 TEATSSTTAEGTSIPTSTPSEGMTPL------TSVPVSNTPVASSEASI-----LSTTPV 3247

Query: 94   QSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTALAGLEA 150
             S++ +          +ST +S+S  ++     PT+ PS  +TP  +   +TT +A  E 
Sbjct: 3248 DSNTPLT---------TSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSET 3298

Query: 151  HTHIDLHSAPPDVTTGLVEHSY-FERPQVASVRSVP 185
             T   L + P D +T +  +S     P +A   S+P
Sbjct: 3299 ST---LSTTPADTSTPVTTYSQASSSPPIADGTSMP 3331



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 42/211 (19%), Positives = 79/211 (37%), Gaps = 19/211 (9%)

Query: 7    PLEAAPLPAEVRESLAELELELSEDVHTEAVQA---ALAKYKERKMPMPSKRRSVLVHSS 63
            P E +PL   +  S   +    +  + T  V +    +   +    P+P++  S+   + 
Sbjct: 2097 PSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTY 2156

Query: 64   VETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHP 123
             +  TP  +   S    +      L++TP+ + + V          +ST + +S T+S  
Sbjct: 2157 SDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVT---------NSTEARSSPTTSEG 2207

Query: 124  GGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHS-YFERPQVASVR 182
               PT+ PS  +TP  +   +   +       L + P D +T +   +     P  A   
Sbjct: 2208 TSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGT 2267

Query: 183  SVPRGCSGSMLETADGVPV------NSRVSS 207
            S+P             +PV      NS VS+
Sbjct: 2268 SIPTSTLSEGTTPLTSIPVSHTLVANSEVST 2298



 Score = 34.7 bits (78), Expect = 0.52
 Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 27/141 (19%)

Query: 49  MPMPSKRRSVLVHSSVETYTPPDTSS----------------ASEDEGSLRRPGRLTSTP 92
           MP+ S   S L  + V+T TP  TSS                ++  EGS        ST 
Sbjct: 521 MPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTR 580

Query: 93  L-----QSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPS---AAATPGAAATTA 144
           L      S +S  P        +S+ +S+SST++     PT+  S      T  + +TT 
Sbjct: 581 LVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTL 640

Query: 145 LAGLEAHTHIDLHSAPPDVTT 165
           +A  EA T   L + P D  T
Sbjct: 641 VASSEAST---LSTTPVDSNT 658



 Score = 34.3 bits (77), Expect = 0.67
 Identities = 42/203 (20%), Positives = 77/203 (37%), Gaps = 19/203 (9%)

Query: 7    PLEAAPLPAEVRESLAELELELSEDVHTEAVQA---ALAKYKERKMPMPSKRRSVLVHSS 63
            P E +PL   +  S   +    +  + T  V +    +   +    P P++  S+   + 
Sbjct: 1626 PSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTY 1685

Query: 64   VETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHP 123
             E  TP  + +      +      L++TP+ + + V          +ST + +S T+S  
Sbjct: 1686 TEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVT---------TSTEARSSPTTSEG 1736

Query: 124  GGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTTGLVEHS-YFERPQVA 179
               P + PS   TP  +   +TT +   EA T   L + P D +T +   +     P  A
Sbjct: 1737 TSMPNSTPSEGTTPLTSIPVSTTPVLSSEAST---LSATPIDTSTPVTTSTEATSSPTTA 1793

Query: 180  SVRSVPRGCSGSMLETADGVPVN 202
               S+P       +      PV+
Sbjct: 1794 EGTSIPTSTLSEGMTPLTSTPVS 1816



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 27/140 (19%)

Query: 50   PMPSKRRSVLVHSSVETYTPPDTSS----------------ASEDEGS-LRRPGRLTSTP 92
            P+ S     L  + V+T TP  TS+                ++  EGS L     +++TP
Sbjct: 2821 PVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTP 2880

Query: 93   LQSHS----SVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTAL 145
            + S      S  P    +   +ST  S+S T++     P + PS  +TP  +   +T  +
Sbjct: 2881 VASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPV 2940

Query: 146  AGLEAHTHIDLHSAPPDVTT 165
            AG EA T   L + P D  T
Sbjct: 2941 AGSEAST---LSTTPVDTRT 2957



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 47/176 (26%), Positives = 72/176 (40%), Gaps = 20/176 (11%)

Query: 57  SVLVHSSVETYTPPDTSSASE------DEGSLRRPGRLTSTPLQSHS-----SVEPWLDR 105
           S LV +S E  + P T+ A+        EGS        ST L + S     S  P   +
Sbjct: 362 STLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSK 421

Query: 106 VIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPD 162
               +++ +S+S T++      T+ PS  +TP  +   +TT +A  EA    +L + P D
Sbjct: 422 TFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEAS---NLSTTPVD 478

Query: 163 VTTGLVEHS-YFERPQVASVRSVPRG--CSGSMLETADGVPVNSRVSSKIQQLLNT 215
             T +   +     P  A V S+P      GS   T+  V      SS+   L  T
Sbjct: 479 SKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTT 534



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 20/103 (19%)

Query: 66  TYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGG 125
           T  P +T+  +  E S      L++TP+ + + V          +ST +S+S T++    
Sbjct: 691 TSMPVNTTLVASSEAST-----LSTTPVDTSTPVT---------TSTEASSSPTTADGAS 736

Query: 126 RPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTT 165
            PT+ PS  +TP  +   + T L   EA T   L + P D +T
Sbjct: 737 MPTSTPSEGSTPLTSMPVSKTLLTSSEAST---LSTTPLDTST 776



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 41/180 (22%), Positives = 70/180 (38%), Gaps = 17/180 (9%)

Query: 50   PMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQG 109
            P P++  S+   +  E  TP  +   +    +      L++TP+ + + V          
Sbjct: 1319 PTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVT--------- 1369

Query: 110  SSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTT- 165
            +ST + +S T+S     P + PS   TP  +   +TT +   EA T   L + P D +T 
Sbjct: 1370 TSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEAST---LSATPVDTSTP 1426

Query: 166  GLVEHSYFERPQVASVRSVPRGCSGSMLETADGVPV-NSRVSSKIQQLLNTLKRPKRPPL 224
            G         P  A   S+P             +PV N+ V++     L+T       P+
Sbjct: 1427 GTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPV 1486



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 40/161 (24%), Positives = 71/161 (44%), Gaps = 23/161 (14%)

Query: 7    PLEAAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVET 66
            P+   P+ +    +L+   ++ S  + T + +A+ +      + +P    S    S++ T
Sbjct: 2462 PVSTTPVVSSEAGTLSTTPVDTSTPM-TTSTEASSSPTTAEDIVVPISTASE--GSTLLT 2518

Query: 67   YTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGR 126
              P  T+  +  E S      L++TP+ S+S V          +ST  S+S+TS+     
Sbjct: 2519 SIPVSTTPVASPEAST-----LSTTPVDSNSPVV---------TSTEISSSATSAEGTSM 2564

Query: 127  PTTAPSAAATP---GAAATTALAGLEAHTHIDLHSAPPDVT 164
            PT+  S  +TP      +T  LA  EA T   L + P D +
Sbjct: 2565 PTSTYSEGSTPLRSMPVSTKPLASSEAST---LSTTPVDTS 2602



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 41/160 (25%), Positives = 64/160 (40%), Gaps = 9/160 (5%)

Query: 57   SVLVHSSVETYTPPDTSSASEDEGSLRR----PGRLTSTPLQSHS-SVEPWLDRVI-QGS 110
            S  V +S E  TP  +SS++    S  +    P   T+ PL   + S  P   R   +G 
Sbjct: 3962 STPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGC 4021

Query: 111  STSSSASSTSS--HPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLV 168
            +TS+S  S +S  H     TT P   ++  +  +T  +     T    HS+ P  T+   
Sbjct: 4022 TTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASS 4081

Query: 169  EHSYFERPQVASVRSVPRGCSGSM-LETADGVPVNSRVSS 207
                 E     + R+ P   + S    T   VP N+ + S
Sbjct: 4082 TTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKS 4121



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 34/120 (28%), Positives = 51/120 (42%), Gaps = 21/120 (17%)

Query: 64   VETYTPPDTSSASEDEGSL------RRPGRLTSTPLQ---------SHSSVEPWLDRVIQ 108
            V TY+   +S  + D+ S+           LTS P+          S  S  P       
Sbjct: 2369 VTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPV 2428

Query: 109  GSSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTT 165
             +ST +S+S T++     PT+ PS   TP A+   +TT +   EA T   L + P D +T
Sbjct: 2429 TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGT---LSTTPVDTST 2485



 Score = 30.8 bits (68), Expect = 7.4
 Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 18/134 (13%)

Query: 88  LTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAA---TTA 144
           L++TP+ S++ V          +ST +++SST++     PT+  +  +TP  +    TT 
Sbjct: 649 LSTTPVDSNTPVT---------TSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTL 699

Query: 145 LAGLEAHTHIDLHSAPPDVTTGLVEHS-YFERPQVASVRSVPRGCSGSMLETADGVPVNS 203
           +A  EA T   L + P D +T +   +     P  A   S+P             +PV+ 
Sbjct: 700 VASSEAST---LSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSK 756

Query: 204 RV--SSKIQQLLNT 215
            +  SS+   L  T
Sbjct: 757 TLLTSSEASTLSTT 770



 Score = 30.8 bits (68), Expect = 7.4
 Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 27/156 (17%)

Query: 64   VETYTPPDTSSASEDEGSLRRPGR------LTSTPLQSHSSVEPWLDRVIQGSSTSSSAS 117
            V TY+   +S  + D  S+  P        LTS PL +   V      +      +S+ +
Sbjct: 1957 VTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPA 2016

Query: 118  STSSHPGGRPTTA---------PSAAATPGA---AATTALAGLEAHTHIDLHSAPPDVTT 165
            +TS+     PTTA         PS   TP A    +TT +   E +T   L + P D  T
Sbjct: 2017 TTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNT---LSTTPVDSKT 2073

Query: 166  GLVEHSYFERPQVASVRSVPRGCSGSMLETADGVPV 201
             +   +       AS  +   G S ++   ++G P+
Sbjct: 2074 QVTNST------EASSSATAEGSSMTISAPSEGSPL 2103



 Score = 30.8 bits (68), Expect = 7.4
 Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 22/128 (17%)

Query: 65   ETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPG 124
            E  TP    S S           L++TP+ + + V          +ST +S S T++   
Sbjct: 3337 EGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVT---------TSTEASLSPTTAEGT 3387

Query: 125  GRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPD----VTTGLVEHSYFERPQ 177
              PT++PS   TP A+   +TT +   E +T   L + P D    VTT     S    P 
Sbjct: 3388 SIPTSSPSEGTTPLASMPVSTTPVVSSEVNT---LSTTPVDSNTLVTTSTEASS---SPT 3441

Query: 178  VASVRSVP 185
            +A   S+P
Sbjct: 3442 IAEGTSLP 3449



 Score = 30.4 bits (67), Expect = 9.7
 Identities = 33/112 (29%), Positives = 48/112 (42%), Gaps = 9/112 (8%)

Query: 110  SSTSSSASSTSSHPGGRPTTAPSAAATPGAAAT---TALAGLEAHTHIDLHSAPPDVTTG 166
            +ST +S+S T++     PT+ PS  +TP  +     T +A  EA T   L + P D +T 
Sbjct: 2784 TSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGT---LSTTPVDTSTP 2840

Query: 167  LVEHS-YFERPQVASVRSVP--RGCSGSMLETADGVPVNSRVSSKIQQLLNT 215
            +   +     P  A    VP      GS L T+  V      SS+   L  T
Sbjct: 2841 VTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTT 2892


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 38.1 bits (87), Expect = 0.047
 Identities = 36/142 (25%), Positives = 55/142 (38%), Gaps = 10/142 (7%)

Query: 30  EDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLT 89
           E+V+T +  A LA       P P    +     S  T  PP +S+  E   +   P   T
Sbjct: 143 ENVNTSSSVATLAPVNS---PAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATT 199

Query: 90  STPLQSHSSVE-----PWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTA 144
             P  S +  E     P          +SS+   T++ P     T P+  ++     TTA
Sbjct: 200 QAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTA 259

Query: 145 LAGLEAHTHID--LHSAPPDVT 164
           +    + T +D    SAPP+ T
Sbjct: 260 VPPTPSATTLDPSSASAPPETT 281



 Score = 37.7 bits (86), Expect = 0.061
 Identities = 54/239 (22%), Positives = 78/239 (32%), Gaps = 35/239 (14%)

Query: 53  SKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVE-----PWLDRVI 107
           S R +V   SSV T  P ++ +  +   +   P   T  P  S +  E     P      
Sbjct: 140 SSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATT 199

Query: 108 QGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGL-EAHTHIDLHSAPPDVTTG 166
           Q   +SS+   T++ P   P T P+  ++     TTA      A T   L S+ P  TT 
Sbjct: 200 QAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTA 259

Query: 167 LVEHSYFERPQVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKE 226
           +        P   S  ++    + +  ET    P  S  +               PP   
Sbjct: 260 V--------PPTPSATTLDPSSASAPPETTAAPPTPSATT-------------PAPPSSP 298

Query: 227 FFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKS 285
              +     +      P    P+ SETS       T  V        T Q   T QP S
Sbjct: 299 APQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSV--------TTQTTTTKQPTS 349


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 38.1 bits (87), Expect = 0.047
 Identities = 36/142 (25%), Positives = 55/142 (38%), Gaps = 10/142 (7%)

Query: 30  EDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLT 89
           E+V+T +  A LA       P P    +     S  T  PP +S+  E   +   P   T
Sbjct: 143 ENVNTSSSVATLAPVNS---PAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATT 199

Query: 90  STPLQSHSSVE-----PWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTA 144
             P  S +  E     P          +SS+   T++ P     T P+  ++     TTA
Sbjct: 200 QAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTA 259

Query: 145 LAGLEAHTHID--LHSAPPDVT 164
           +    + T +D    SAPP+ T
Sbjct: 260 VPPTPSATTLDPSSASAPPETT 281



 Score = 37.7 bits (86), Expect = 0.061
 Identities = 54/239 (22%), Positives = 78/239 (32%), Gaps = 35/239 (14%)

Query: 53  SKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVE-----PWLDRVI 107
           S R +V   SSV T  P ++ +  +   +   P   T  P  S +  E     P      
Sbjct: 140 SSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATT 199

Query: 108 QGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGL-EAHTHIDLHSAPPDVTTG 166
           Q   +SS+   T++ P   P T P+  ++     TTA      A T   L S+ P  TT 
Sbjct: 200 QAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTA 259

Query: 167 LVEHSYFERPQVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKE 226
           +        P   S  ++    + +  ET    P  S  +               PP   
Sbjct: 260 V--------PPTPSATTLDPSSASAPPETTAAPPTPSATT-------------PAPPSSP 298

Query: 227 FFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKS 285
              +     +      P    P+ SETS       T  V        T Q   T QP S
Sbjct: 299 APQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSV--------TTQTTTTKQPTS 349


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 38.1 bits (87), Expect = 0.047
 Identities = 36/142 (25%), Positives = 55/142 (38%), Gaps = 10/142 (7%)

Query: 30  EDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLT 89
           E+V+T +  A LA       P P    +     S  T  PP +S+  E   +   P   T
Sbjct: 143 ENVNTSSSVATLAPVNS---PAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATT 199

Query: 90  STPLQSHSSVE-----PWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTA 144
             P  S +  E     P          +SS+   T++ P     T P+  ++     TTA
Sbjct: 200 QAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTA 259

Query: 145 LAGLEAHTHID--LHSAPPDVT 164
           +    + T +D    SAPP+ T
Sbjct: 260 VPPTPSATTLDPSSASAPPETT 281



 Score = 37.7 bits (86), Expect = 0.061
 Identities = 54/239 (22%), Positives = 78/239 (32%), Gaps = 35/239 (14%)

Query: 53  SKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVE-----PWLDRVI 107
           S R +V   SSV T  P ++ +  +   +   P   T  P  S +  E     P      
Sbjct: 140 SSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATT 199

Query: 108 QGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGL-EAHTHIDLHSAPPDVTTG 166
           Q   +SS+   T++ P   P T P+  ++     TTA      A T   L S+ P  TT 
Sbjct: 200 QAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTA 259

Query: 167 LVEHSYFERPQVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKE 226
           +        P   S  ++    + +  ET    P  S  +               PP   
Sbjct: 260 V--------PPTPSATTLDPSSASAPPETTAAPPTPSATT-------------PAPPSSP 298

Query: 227 FFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKS 285
              +     +      P    P+ SETS       T  V        T Q   T QP S
Sbjct: 299 APQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSV--------TTQTTTTKQPTS 349


>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
          Length = 354

 Score = 38.1 bits (87), Expect = 0.047
 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 12/81 (14%)

Query: 80  GSLRRPGRLTSTPLQ----SHSSVEPWLDRVIQGSSTSSSASSTSSHP--------GGRP 127
           G+  RP +  S+P++    S SS +     V   +S+SSSASS+S++P        GG P
Sbjct: 102 GTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNP 161

Query: 128 TTAPSAAATPGAAATTALAGL 148
             A S+ +TP A++  + A +
Sbjct: 162 VAAASSLSTPAASSIWSPASI 182


>gi|111120318 NK6 transcription factor related, locus 1 [Homo
           sapiens]
          Length = 367

 Score = 37.7 bits (86), Expect = 0.061
 Identities = 40/122 (32%), Positives = 56/122 (45%), Gaps = 20/122 (16%)

Query: 68  TPPDTSSASEDEGS---LRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPG 124
           +PP   SA+   G    L RP    S P+ S ++        +  +S S S+SS+SS   
Sbjct: 85  SPPQQLSAATPHGINDILSRP----SMPVASGAA--------LPSASPSGSSSSSSSSAS 132

Query: 125 GRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSV 184
               +A +AAA   AAA ++ AGL A        +PP    GL    YF  P  A+V +V
Sbjct: 133 ASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGL----YFS-PSAAAVAAV 187

Query: 185 PR 186
            R
Sbjct: 188 GR 189


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 37.4 bits (85), Expect = 0.079
 Identities = 62/236 (26%), Positives = 88/236 (37%), Gaps = 49/236 (20%)

Query: 66  TYTPPDTS-SASEDEGSL-RRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHP 123
           T TPP  S + +    SL R+P R + T + S +S+   +D     + T   AS T + P
Sbjct: 386 TGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITK-MDSTASPTRTPPRASPTGTPP 444

Query: 124 GGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRS 183
              PT  PS A+  G  +T +  G  +       +A P   TG         P  AS   
Sbjct: 445 RASPTGTPSRASPTGTQSTASPTGSPS-------TASP---TG--------SPSTASPTG 486

Query: 184 VPRGCSGSMLETADGVPVNSRVS-SKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPD 242
            P     S+  T       SR S +K++   +  + P R                     
Sbjct: 487 SP--SRASLTRTP------SRASLTKMESTASITRTPSRAS---------------PTWT 523

Query: 243 PNQPKPEGS-ETSVLRGEPLTAGVPRPP---SLLATLQRWGTTQPKSPCLTALDTT 294
           P+   P GS  T++  G P  A + R P   SL  T  R   T P    LT   +T
Sbjct: 524 PSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPST 579



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 53/202 (26%), Positives = 74/202 (36%), Gaps = 43/202 (21%)

Query: 112 TSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHS 171
           T S AS T       PT  PS A+  G+ +T +L GL + T     + P    TG     
Sbjct: 343 TPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSS-TASPTGTPPRASPTG----- 396

Query: 172 YFERPQVASV-RSVPRGCSGSMLETADGVPVNSRVS-SKIQQLLNTLKRPKR------PP 223
               P  AS+ R  PR     ML         SR S +K+    +  + P R      PP
Sbjct: 397 ---TPSTASLTRKPPRASPTGML---------SRTSITKMDSTASPTRTPPRASPTGTPP 444

Query: 224 LKEFFVDDFEELLEVQQPDPNQPKPEGSE-TSVLRGEPLTA---GVPRPPSLLATLQRWG 279
                              P++  P G++ T+   G P TA   G P   S   +  R  
Sbjct: 445 RAS------------PTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRAS 492

Query: 280 TTQ-PKSPCLTALDTTGKAVYT 300
            T+ P    LT +++T     T
Sbjct: 493 LTRTPSRASLTKMESTASITRT 514



 Score = 30.4 bits (67), Expect = 9.7
 Identities = 36/167 (21%), Positives = 64/167 (38%), Gaps = 18/167 (10%)

Query: 63  SVETYTPPDTSSASEDEGS------LRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 116
           S  T +P  + S +   GS       R P R + T ++S +S+          + T S A
Sbjct: 469 SPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASI----------TRTPSRA 518

Query: 117 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 176
           S T +     PT +PS A   G+ +  AL    +   +    +   +TT     S    P
Sbjct: 519 SPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTP-SRASLTRTP 577

Query: 177 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPP 223
               +  +P   S + + +    P     S+ + ++ +T    + PP
Sbjct: 578 STVLLTRMPPSASPTGMPSRTS-PTGMPSSALLTKMDSTASITRTPP 623


>gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 [Homo
            sapiens]
          Length = 2542

 Score = 37.4 bits (85), Expect = 0.079
 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 21/87 (24%)

Query: 66   TYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRV----------IQGSSTSSS 115
            T+ P  TS A           +L+S  ++S S+V P  ++V             SST++S
Sbjct: 2002 TFLPASTSQA-----------QLSSQKMESFSAVPPTKEKVSTQDQPMANLCTPSSTANS 2050

Query: 116  ASSTSSHPGGRPTTAPSAAATPGAAAT 142
             SS++S+  G P T PS++ TP ++ T
Sbjct: 2051 CSSSASNTPGAPETHPSSSPTPTSSNT 2077


>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
          Length = 2617

 Score = 37.4 bits (85), Expect = 0.079
 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 21/87 (24%)

Query: 66   TYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRV----------IQGSSTSSS 115
            T+ P  TS A           +L+S  ++S S+V P  ++V             SST++S
Sbjct: 2002 TFLPASTSQA-----------QLSSQKMESFSAVPPTKEKVSTQDQPMANLCTPSSTANS 2050

Query: 116  ASSTSSHPGGRPTTAPSAAATPGAAAT 142
             SS++S+  G P T PS++ TP ++ T
Sbjct: 2051 CSSSASNTPGAPETHPSSSPTPTSSNT 2077


>gi|20270323 zinc finger protein 653 [Homo sapiens]
          Length = 615

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 58/235 (24%), Positives = 88/235 (37%), Gaps = 50/235 (21%)

Query: 91  TPLQSHSSVEPWLDRVIQG-------SSTSSSASSTSSHPGGRPTTAPSAAATPGAAATT 143
           +PL+  S  +P  D+V  G       SS+S SAS +   P G+P  A +AAA     +  
Sbjct: 172 SPLKPLSDSDPDSDKVGNGLVAGSSDSSSSGSASDSEESPEGQPVKAAAAAAAATPTSPV 231

Query: 144 ALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCSGSMLETADGVPVNS 203
             +GL     + +   P D     V H      Q   + S P G     LET   VPV  
Sbjct: 232 GSSGLITQEGVHI---PFD-----VHHVESLAEQGTPLCSNPAGNGPEALETVVCVPVPV 283

Query: 204 RVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRG---EP 260
           +V +    L   + +              E L EV    P      GS+  ++ G   + 
Sbjct: 284 QVGAGPSALFENVPQ--------------EALGEVVASCPMPGMVPGSQVIIIAGPGYDA 329

Query: 261 LTA-----------GVPR-------PPSLLATLQRWGTTQPKSPCLTALDTTGKA 297
           LTA           GVP        P +++  +  +  T+P+    + +D T  A
Sbjct: 330 LTAEGIHLNMAAGSGVPGSGLGEEVPCAMMEGVAAYTQTEPEGSQPSTMDATAVA 384


>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
           sapiens]
          Length = 1135

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 46/197 (23%), Positives = 81/197 (41%), Gaps = 40/197 (20%)

Query: 9   EAAPLPAEVRESLAELELELSEDVHTEAVQ----AALAKYK---------ERKMPMPSKR 55
           EA P+P +  E +A+ +  +SED H E++Q    +A   +           +K  +P++ 
Sbjct: 583 EATPVPIKDME-IAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEE 641

Query: 56  RSVLVHSSVETYTPPDTSSASEDEGSLRRP----------GRLTSTPLQSHSSVEPWLDR 105
            SVL             S  S +   + RP          G   +TP   +  + P  ++
Sbjct: 642 DSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTP--PNKELPPSPEK 699

Query: 106 VIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTT 165
             +  +T+  A +++S    +PT+ P   A       T + GL        +  P  + +
Sbjct: 700 KTKPLATTQPAKTSTSKAKTQPTSLPKQPAP------TTIGGL--------NKKPMSLAS 745

Query: 166 GLVEHSYFERPQVASVR 182
           GLV  +  +RP VAS R
Sbjct: 746 GLVPAAPPKRPAVASAR 762



 Score = 30.4 bits (67), Expect = 9.7
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 10/90 (11%)

Query: 32  VHTEAVQAALAKYKERKMPMP-SKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTS 90
           + TE   A + K   + +P   S+ +S    S  +T T   T+ A+   G +  P R+ +
Sbjct: 837 IKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA---GVV--PSRVKA 891

Query: 91  TPLQSHSSVEPWLDRVIQGSSTSSSASSTS 120
           TP+ S  S  P++D+      TS+  SST+
Sbjct: 892 TPMPSRPSTTPFIDK----KPTSAKPSSTT 917


>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo
           sapiens]
          Length = 1152

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 46/197 (23%), Positives = 81/197 (41%), Gaps = 40/197 (20%)

Query: 9   EAAPLPAEVRESLAELELELSEDVHTEAVQ----AALAKYK---------ERKMPMPSKR 55
           EA P+P +  E +A+ +  +SED H E++Q    +A   +           +K  +P++ 
Sbjct: 583 EATPVPIKDME-IAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEE 641

Query: 56  RSVLVHSSVETYTPPDTSSASEDEGSLRRP----------GRLTSTPLQSHSSVEPWLDR 105
            SVL             S  S +   + RP          G   +TP   +  + P  ++
Sbjct: 642 DSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTP--PNKELPPSPEK 699

Query: 106 VIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTT 165
             +  +T+  A +++S    +PT+ P   A       T + GL        +  P  + +
Sbjct: 700 KTKPLATTQPAKTSTSKAKTQPTSLPKQPAP------TTIGGL--------NKKPMSLAS 745

Query: 166 GLVEHSYFERPQVASVR 182
           GLV  +  +RP VAS R
Sbjct: 746 GLVPAAPPKRPAVASAR 762



 Score = 30.4 bits (67), Expect = 9.7
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 10/90 (11%)

Query: 32  VHTEAVQAALAKYKERKMPMP-SKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTS 90
           + TE   A + K   + +P   S+ +S    S  +T T   T+ A+   G +  P R+ +
Sbjct: 837 IKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA---GVV--PSRVKA 891

Query: 91  TPLQSHSSVEPWLDRVIQGSSTSSSASSTS 120
           TP+ S  S  P++D+      TS+  SST+
Sbjct: 892 TPMPSRPSTTPFIDK----KPTSAKPSSTT 917


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 64/261 (24%), Positives = 91/261 (34%), Gaps = 24/261 (9%)

Query: 47   RKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRV 106
            +K+ +PS  R   V S+     P  TS AS   G++   G  +S  L   +S+ P     
Sbjct: 994  QKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVAL-GFTSLGPSGPAF 1052

Query: 107  IQ-----GSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPP 161
            +Q     G +   +       P   P   P+ AA  G   T   +G  A T     + P 
Sbjct: 1053 VQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPS 1112

Query: 162  DVTTGLVEH-SYFERPQVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPK 220
                 LV   +    P  A++  +P+G       TA   P +   S+    +  +L  PK
Sbjct: 1113 QAPPSLVYTVATSTTPPAATI--LPKGPPAPA--TATPAPTSPFPSATAGSMTYSLVAPK 1168

Query: 221  --RPPLK----------EFFVDDFEELLEVQQ-PDPNQPKPEGSETSVLRGEPLTAGVPR 267
              RP  K             V  FE     +  P P QP   G        E    G P 
Sbjct: 1169 AQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPT 1228

Query: 268  PPSLLATLQRWGTTQPKSPCL 288
            PP+     + W  T   SP L
Sbjct: 1229 PPAPPPLPETWTPTARSSPPL 1249


>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
          Length = 2013

 Score = 36.2 bits (82), Expect = 0.18
 Identities = 35/153 (22%), Positives = 59/153 (38%), Gaps = 13/153 (8%)

Query: 4    RGCPLEAAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSS 63
            RGCP+ + P+ A    S   +    S     ++    L        P  S   +   H++
Sbjct: 1845 RGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTS---TTYAHTT 1901

Query: 64   VETYTP-------PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQG---SSTS 113
              T  P       P T + S    S       T +P+ + S++      +      S+TS
Sbjct: 1902 STTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS 1961

Query: 114  SSASSTSSHPGGRPTTAPSAAATPGAAATTALA 146
            +  SST+S P    T+AP+++ T     +T  A
Sbjct: 1962 APTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSA 1994


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 70/316 (22%), Positives = 114/316 (36%), Gaps = 46/316 (14%)

Query: 52    PSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVE-----PWLDRV 106
             P    + L H +  + T   T       GS   P  +TS  + + S V      P +  V
Sbjct: 11571 PETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGV 11630

Query: 107   IQGSSTSSSASSTSSHPG-----GRPTTAPSAAATPGAAA--TTALAGLEAH-------- 151
             +    TSS+  ++++ P      G P T  S+A  PG     T  +  + +         
Sbjct: 11631 VTSQVTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASW 11690

Query: 152   -THIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCSGSMLETADGVP--VNSRVSSK 208
              TH    S P   TT    HS  +   V +        S  +   + G P  V S+++S 
Sbjct: 11691 VTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSS 11750

Query: 209   IQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRP 268
                   T+      P           + E        P+ E S+T      P +   P+ 
Sbjct: 11751 GAATSTTVPTLTHSP----------GMPETTALLSTHPRTETSKTF-----PASTVFPQV 11795

Query: 269   PSLLATLQRWGTTQPKSPCLTALDT-TGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEP 327
                 A+L    T +P +   TAL T T  +++TL      +  + L+ T    +++K  P
Sbjct: 11796 SETTASL----TIRPGAETSTALPTQTTSSLFTLLV--TGTSRVDLSPTASPGVSAKTAP 11849

Query: 328   L-LKPGDRVALVFPNS 342
             L   PG   + + P S
Sbjct: 11850 LSTHPGTETSTMIPTS 11865



 Score = 33.9 bits (76), Expect = 0.88
 Identities = 55/225 (24%), Positives = 85/225 (37%), Gaps = 36/225 (16%)

Query: 67  YTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGR 126
           ++ P+  SA   + S       TS PL S +SV   L+  +  +ST S   +TSS   G 
Sbjct: 707 FSSPEPDSAGHTKIS-------TSIPLLSSASV---LEDKVSATSTFSHHKATSSITTGT 756

Query: 127 PTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPR 186
           P    S    P +A  +++    A T  +      + T+ L   S        SV ++  
Sbjct: 757 PEI--STKTKPSSAVLSSMTLSNAATSPE---RVRNATSPLTHPSPSGEETAGSVLTL-- 809

Query: 187 GCSGSMLETADGVPVN--SRVSSKIQQLLNTLKRPKRPPLKEFFVDDF---------EEL 235
               +  ET D   ++    ++S+  +  +TL  P    +K  F             EE 
Sbjct: 810 ---STSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEET 866

Query: 236 LEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGT 280
            E   P  +QP     ETSV R     A    P  +  T+  W T
Sbjct: 867 EETSNPSVSQP-----ETSVSRVRTTLASTSVPTPVFPTMDTWPT 906



 Score = 33.9 bits (76), Expect = 0.88
 Identities = 38/155 (24%), Positives = 63/155 (40%), Gaps = 12/155 (7%)

Query: 1    MADRGCPLEAAPL--PAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSV 58
            + +R     AAP   P  +  S  E      ++  T      L   K  ++P  S   S 
Sbjct: 2313 LGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSD 2372

Query: 59   LVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASS 118
            L+++S+ + T   T +AS    S+   G   S+     SS  P +      ++T++S S 
Sbjct: 2373 LINTSIASSTMDVTKTASISPTSIS--GMTASSSPSLFSSDRPQVPTSTTETNTATSPSV 2430

Query: 119  TS--------SHPGGRPTTAPSAAATPGAAATTAL 145
            +S        S+ GG P+T P    T     ++AL
Sbjct: 2431 SSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSAL 2465



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 32/132 (24%), Positives = 47/132 (35%), Gaps = 27/132 (20%)

Query: 61    HSSVETYTPPDTSSASEDEGSLRR------PGRLTSTPLQSHSSVEPWLDRVIQGSSTSS 114
             HS ++T     TS  +E   ++        PG LTS    S   +      V +    S 
Sbjct: 11286 HSELDTMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESE 11345

Query: 115   SASSTSSHPGGR---------------PTTAPSAAATPGAAATTALAGLEAHTHIDLHSA 159
             + +S  +HP                  P T PS A +PGA AT+    +     +     
Sbjct: 11346 ATASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDV----- 11400

Query: 160   PPDVTTGLVEHS 171
              PD+ T  V  S
Sbjct: 11401 -PDMVTSQVTSS 11411



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 44/206 (21%), Positives = 79/206 (38%), Gaps = 10/206 (4%)

Query: 25   ELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRR 84
            E  +S+++ T + + +   YKE         R+ +  SS  ++  PD S+ S D  S   
Sbjct: 4899 ETSISQEI-TSSTETSTVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDI-STET 4956

Query: 85   PGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTA 144
              RL+++P+ + S+ E  +         +S  + T       P     +A T G +    
Sbjct: 4957 NTRLSTSPIMTESA-EITITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDV 5015

Query: 145  LAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCSGSMLETADGVPVNSR 204
               +         ++PP V       S+   P +    + P   S ++ E     P+ S 
Sbjct: 5016 TTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAM----TTPSLISSTLPEDKLSSPMTSL 5071

Query: 205  VSS---KIQQLLNTLKRPKRPPLKEF 227
            ++S   KI  +L T   P    L  F
Sbjct: 5072 LTSGLVKITDILRTRLEPVTSSLPNF 5097



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 42/176 (23%), Positives = 71/176 (40%), Gaps = 33/176 (18%)

Query: 51    MPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHS------------- 97
             +P    S++  S   T T   T + S DE         T+T L +HS             
Sbjct: 11148 VPGMVTSLVTSSRAVTSTTIPTLTISSDEPE-------TTTSLVTHSEAKMISAIPTLAV 11200

Query: 98    --SVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGL-----EA 150
               +V+  +  ++  S + +SA S  +    +P T  S  A PG  A++ +  L     E 
Sbjct: 11201 SPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTVSTGEP 11260

Query: 151   HTHIDLHSAPPDVTTGL----VEHSYFERPQVASVRSVPRGCSGSMLET--ADGVP 200
              T+I L + P + ++ L       S+ E   + S  + P   S S + T  + G+P
Sbjct: 11261 FTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAISTTISPGIP 11316



 Score = 32.0 bits (71), Expect = 3.3
 Identities = 69/314 (21%), Positives = 108/314 (34%), Gaps = 53/314 (16%)

Query: 25    ELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPD---TSSASEDEGS 81
             EL  S  +H+E  +A            P    S +  +S+ T  P +   T   +E    
Sbjct: 10115 ELYSSVSIHSEPSKATY----------PVGTPSSMAETSISTSMPANFETTGFEAEPFSH 10164

Query: 82    LRRPGRLTSTPLQSHSSV------EPWLDRVIQGSSTSSSASSTSSHPGGRPTT------ 129
             L    R T+  L + S         P    ++Q S T  ++S+ +S P   P +      
Sbjct: 10165 LTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIP 10224

Query: 130   ---------APSAAATPGAAA------TTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFE 174
                      +PS   + G  +      T ++     H   DL  +   ++TG V  S  E
Sbjct: 10225 VDIITPFNASPSITESTGITSFPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSE 10284

Query: 175   RPQVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKR--PKRPPL----KEFF 228
                  +   VPR  SGS      G P +   S      L+T+    P   P+      F 
Sbjct: 10285 AMTSFATTGVPRAISGS------GSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFT 10338

Query: 229   VDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCL 288
               D   +  + +   +   P   +TS+      T G     S L T  + G T   SP L
Sbjct: 10339 TTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTS-SSPIL 10397

Query: 289   TALDTTGKAVYTLT 302
                 T    + T+T
Sbjct: 10398 DTRMTESVELGTVT 10411



 Score = 30.4 bits (67), Expect = 9.7
 Identities = 28/115 (24%), Positives = 44/115 (38%), Gaps = 17/115 (14%)

Query: 36    AVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQS 95
             A   +L  +  +  P      S+  HS  +T     TS  +E   ++  P   T  P   
Sbjct: 10819 ATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVP--- 10875

Query: 96    HSSVEPWLDRVIQGSSTSSSASSTSSHP-----GGRPTTAPSAAATPGAAATTAL 145
                       V+    TSS A  +++ P      G P T PS A + G  A++A+
Sbjct: 10876 ---------GVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAI 10921


>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
           to, 10 isoform b [Homo sapiens]
          Length = 1011

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 49/197 (24%), Positives = 81/197 (41%), Gaps = 28/197 (14%)

Query: 43  KYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRR----PGRLTSTPLQSHSS 98
           K+K++  P P+   S+ V ++ +TYT    +S S   GSL+R      R T+   Q  S+
Sbjct: 244 KHKKQPEPSPALVPSLTV-TTEKTYTSTSNNSIS---GSLKRLEDTTARFTNANFQEVSA 299

Query: 99  VEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPG---AAATTALAGLEAHTHID 155
                  V +   +      +S+H  G+    P     PG   +AA+    G  + T   
Sbjct: 300 HTSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGS 359

Query: 156 LHS-------APPD----VTTGLVEHSYFERPQVASVRSVPRGCSGSM------LETADG 198
           + S       +P D      + L   SY    Q ++ + V +G SGS         T  G
Sbjct: 360 VKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIG 419

Query: 199 VPVNSRVSSKIQQLLNT 215
           +P  S V+S+ +   N+
Sbjct: 420 LPSTSAVTSQPKSFENS 436


>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
           to, 10 isoform a [Homo sapiens]
          Length = 1027

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 49/197 (24%), Positives = 81/197 (41%), Gaps = 28/197 (14%)

Query: 43  KYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRR----PGRLTSTPLQSHSS 98
           K+K++  P P+   S+ V ++ +TYT    +S S   GSL+R      R T+   Q  S+
Sbjct: 244 KHKKQPEPSPALVPSLTV-TTEKTYTSTSNNSIS---GSLKRLEDTTARFTNANFQEVSA 299

Query: 99  VEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPG---AAATTALAGLEAHTHID 155
                  V +   +      +S+H  G+    P     PG   +AA+    G  + T   
Sbjct: 300 HTSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGS 359

Query: 156 LHS-------APPD----VTTGLVEHSYFERPQVASVRSVPRGCSGSM------LETADG 198
           + S       +P D      + L   SY    Q ++ + V +G SGS         T  G
Sbjct: 360 VKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIG 419

Query: 199 VPVNSRVSSKIQQLLNT 215
           +P  S V+S+ +   N+
Sbjct: 420 LPSTSAVTSQPKSFENS 436


>gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Homo
           sapiens]
          Length = 728

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 10/87 (11%)

Query: 187 GCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPD--PN 244
           G SGSM  T      N  +  +I+ +        +  + E   DD +E +   +P+  P 
Sbjct: 439 GHSGSMARTQQAAQANITLQEQIEAI-----HKAKGLVPE---DDTKEKIGPSKPNEIPQ 490

Query: 245 QPKPEGSETSVLRGEPLTAGVPRPPSL 271
           QP P  S T++    P    VPRPP++
Sbjct: 491 QPPPPSSATNIPSSAPPITSVPRPPTM 517


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,443,558
Number of Sequences: 37866
Number of extensions: 2194129
Number of successful extensions: 9218
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 159
Number of HSP's that attempted gapping in prelim test: 8605
Number of HSP's gapped (non-prelim): 673
length of query: 1110
length of database: 18,247,518
effective HSP length: 113
effective length of query: 997
effective length of database: 13,968,660
effective search space: 13926754020
effective search space used: 13926754020
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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