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Search of human proteins with 225637473
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
(848 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225637473 solute carrier organic anion transporter family, me... 1720 0.0
gi|225637475 solute carrier organic anion transporter family, me... 1566 0.0
gi|225637477 solute carrier organic anion transporter family, me... 1361 0.0
gi|39777594 solute carrier organic anion transporter family memb... 421 e-117
gi|222831573 solute carrier organic anion transporter family, me... 397 e-110
gi|222831575 solute carrier organic anion transporter family, me... 395 e-110
gi|38679890 solute carrier organic anion transporter family, mem... 394 e-109
gi|223634012 solute carrier organic anion transporter family, me... 348 9e-96
gi|6005820 solute carrier organic anion transporter family, memb... 348 9e-96
gi|188528663 solute carrier organic anion transporter family, me... 340 4e-93
gi|9790233 solute carrier organic anion transporter family, memb... 338 2e-92
gi|225543525 solute carrier organic anion transporter family, me... 330 4e-90
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 325 1e-88
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 325 1e-88
gi|8394291 solute carrier organic anion transporter family, memb... 318 1e-86
gi|225543118 solute carrier organic anion transporter family, me... 310 3e-84
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 307 2e-83
gi|225543116 solute carrier organic anion transporter family, me... 283 5e-76
gi|223634014 solute carrier organic anion transporter family, me... 268 1e-71
gi|93277099 solute carrier organic anion transporter family, mem... 265 1e-70
gi|225543114 solute carrier organic anion transporter family, me... 249 1e-65
gi|194239645 spinster homolog 3 [Homo sapiens] 50 1e-05
gi|29568105 transmembrane protein with EGF-like and two follista... 46 2e-04
gi|185136021 spinster homolog 2 [Homo sapiens] 43 0.001
gi|215490102 spinster homolog 1 isoform 3 [Homo sapiens] 39 0.020
gi|215490096 spinster homolog 1 isoform 1 [Homo sapiens] 39 0.020
gi|14042968 spinster homolog 1 isoform 1 [Homo sapiens] 39 0.020
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 38 0.045
gi|215490100 spinster homolog 1 isoform 2 [Homo sapiens] 38 0.045
gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo ... 36 0.17
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 1720 bits (4454), Expect = 0.0
Identities = 848/848 (100%), Positives = 848/848 (100%)
Query: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA
Sbjct: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
Query: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL
Sbjct: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
Query: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV
Sbjct: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
Query: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG
Sbjct: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
Query: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL
Sbjct: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
Query: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL
Sbjct: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
Query: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420
VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD
Sbjct: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420
Query: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480
LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP
Sbjct: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480
Query: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540
SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT
Sbjct: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540
Query: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600
GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE
Sbjct: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600
Query: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF
Sbjct: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
Query: 661 ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC 720
ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC
Sbjct: 661 ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC 720
Query: 721 GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTV 780
GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTV
Sbjct: 721 GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTV 780
Query: 781 SERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEES 840
SERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEES
Sbjct: 781 SERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEES 840
Query: 841 PAALEPPS 848
PAALEPPS
Sbjct: 841 PAALEPPS 848
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 1566 bits (4055), Expect = 0.0
Identities = 781/848 (92%), Positives = 785/848 (92%), Gaps = 55/848 (6%)
Query: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA
Sbjct: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
Query: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL
Sbjct: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
Query: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV
Sbjct: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
Query: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG
Sbjct: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
Query: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL
Sbjct: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
Query: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL
Sbjct: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
Query: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420
VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVR
Sbjct: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRG 420
Query: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480
+ +P++ I G
Sbjct: 421 V-----------------------------------------IIVPSAGVGIVLG----- 434
Query: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540
GYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT
Sbjct: 435 ---------GYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 485
Query: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600
GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE
Sbjct: 486 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 545
Query: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF
Sbjct: 546 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 605
Query: 661 ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC 720
ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC
Sbjct: 606 ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC 665
Query: 721 GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTV 780
GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTV
Sbjct: 666 GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTV 725
Query: 781 SERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEES 840
SERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEES
Sbjct: 726 SERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEES 785
Query: 841 PAALEPPS 848
PAALEPPS
Sbjct: 786 PAALEPPS 793
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 1361 bits (3522), Expect = 0.0
Identities = 674/674 (100%), Positives = 674/674 (100%)
Query: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA
Sbjct: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
Query: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL
Sbjct: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
Query: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV
Sbjct: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
Query: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG
Sbjct: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
Query: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL
Sbjct: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
Query: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL
Sbjct: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
Query: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420
VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD
Sbjct: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420
Query: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480
LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP
Sbjct: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480
Query: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540
SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT
Sbjct: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540
Query: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600
GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE
Sbjct: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600
Query: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF
Sbjct: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
Query: 661 ITACAQPSAIIVTL 674
ITACAQPSAIIVTL
Sbjct: 661 ITACAQPSAIIVTL 674
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 421 bits (1082), Expect = e-117
Identities = 241/651 (37%), Positives = 350/651 (53%), Gaps = 53/651 (8%)
Query: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
VL + L +C F+Q + V+G++++VIT++ERRY L S +SGL+ S +DI + +
Sbjct: 98 VLNTPKGILFFLCAAAFLQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCL 157
Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
FVSYFGG G +P WL G LL+ G+ +FALPHF + Y++ EL+A G
Sbjct: 158 TFVSYFGGSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEV-ELDA----------GVR 206
Query: 243 TATLEPPA-CPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLY 301
T P A C + G + Y +F+ Q L G+G+TP+YTLG TYLD+NVK S +Y
Sbjct: 207 TCPANPGAVCADSTSGLSR--YQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVY 264
Query: 302 LAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLV 361
+AI Y LGPA GYL+GG L+ Y + L P ++G WW GFL A F
Sbjct: 265 IAIFYTAAILGPAAGYLIGGALLNIYTEMGRRTELTTESPLWVGAWWVGFLGSGAAAFFT 324
Query: 362 IFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDL 421
P+ +P++LP ++++V ++ LK+ S + S+ FGK +RDL
Sbjct: 325 AVPILGYPRQLP------GSQRYAVMRAAEMHQLKDSSRG------EASNPDFGKTIRDL 372
Query: 422 PRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPS 481
P + +L N TF+ + L+ E+ ++T TF PKF+ESQF + AS A+ G ++VP+
Sbjct: 373 PLSIWLLLKNPTFILLCLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPA 432
Query: 482 AGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTG 541
G G LGG+ + KL+L K + C+ VSLL +F + C S+ + G+ Y G
Sbjct: 433 GGGGTFLGGFFVNKLRLRGSAVIKFCLFCTVVSLLGI-LVFSLHCPSVPMAGVTASY-GG 490
Query: 542 PSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLST-GIRNYTE 600
L H NLT CN C C+ Y PVCGSDG+ YF+ C AGC + + G + Y +
Sbjct: 491 SLLPEGHLNLTAPCNAACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRD 550
Query: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
C+C I + + G+A +GKC TC LVF+F+V F
Sbjct: 551 CSC---------------------IPQNLSSGFGHATAGKCTSTCQRKPLLLVFIFVVIF 589
Query: 661 ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC 720
T + A+ TLR V D +R FALG+Q++++R L IP PI FG VID C+LWQ +C
Sbjct: 590 FTFLSSIPALTATLRCVRDPQRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQDQC 649
Query: 721 GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK---YKEDGLQ 768
G QGSC Y ++ + K +G +F +A + K DGL+
Sbjct: 650 GQQGSCLVYQNSAMSRYILIMGLLYKVLGVLFFAIACFLYKPLSESSDGLE 700
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 397 bits (1021), Expect = e-110
Identities = 235/689 (34%), Positives = 369/689 (53%), Gaps = 55/689 (7%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
+ FLV C L Q V YL SV+TT+ERR++L+S++ G++ S F+IGNL +++FVSY
Sbjct: 40 KIFLVSECALMLAQGT-VGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSY 98
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQ--ELNASAPNDGLCQGGNSTAT 245
FG RG RP + GG+++A GA L ALP F++ Y+ + E+ A +C S
Sbjct: 99 FGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGD 158
Query: 246 LEPPA---CPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYL 302
P C + N ++ L I AQ+L+G+G+TP+ LG +Y+DD+V++++SSLY+
Sbjct: 159 EGPDPDLICRNRTATNMMYL---LLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYI 215
Query: 303 AIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSGFLLCAIAM 358
I++ M GPA G++LG YVD + + + +DPR+IG WW GFLLC +
Sbjct: 216 GILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALL 275
Query: 359 FLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDV 418
F MF FP+ LPP + + + ++ + + + K + + SS + +
Sbjct: 276 FFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQL 335
Query: 419 RDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVII 478
R +P+ +LSN F + L+ E A+V F F+ K++E QF + S+A+ G+
Sbjct: 336 RVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTA 395
Query: 479 VPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPY 538
+P A +GI LGG ++KKL L A + ++AM+ + VS C+ + +GC++ + G+ +PY
Sbjct: 396 IPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPY 455
Query: 539 --TTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIR 596
+T P + + CN NC C+ + PVCG+DGITY + C AGC NS NL
Sbjct: 456 GNSTAPGSALDPYS---PCNNNCECQTDSFTPVCGADGITYLSACFAGC-NSTNL----- 506
Query: 597 NYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT-CN-TLIPFLVF 654
T C C+ T EN V GKC C + FL
Sbjct: 507 --TGCACLT----------------------TVPAENATVVPGKCPSPGCQEAFLTFLCV 542
Query: 655 LFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCM 714
+ I + I A AQ ++I+ +R+V E + +ALG+ F+LLR L +IP P+ FGA ID+TC+
Sbjct: 543 MCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCL 602
Query: 715 LWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQRE 774
W CG QG+C Y+ +R++Y +A LK FI W + +++ + + E
Sbjct: 603 FWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCL--RKNYKRYIKNHE 660
Query: 775 FPLSTVSERVGHPDNARTRSCPAFSTQGE 803
LST +E + D ++CP + E
Sbjct: 661 GGLSTSTE---YQDIETEKTCPESHSPSE 686
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 395 bits (1015), Expect = e-110
Identities = 226/647 (34%), Positives = 351/647 (54%), Gaps = 50/647 (7%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
+ FLV C L Q V YL SV+TT+ERR++L+S++ G++ S F+IGNL +++FVSY
Sbjct: 40 KIFLVSECALMLAQGT-VGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSY 98
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQ--ELNASAPNDGLCQGGNSTAT 245
FG RG RP + GG+++A GA L ALP F++ Y+ + E+ A +C S
Sbjct: 99 FGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGD 158
Query: 246 LEPPA---CPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYL 302
P C + N ++ L I AQ+L+G+G+TP+ LG +Y+DD+V++++SSLY+
Sbjct: 159 EGPDPDLICRNRTATNMMYL---LLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYI 215
Query: 303 AIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSGFLLCAIAM 358
I++ M GPA G++LG YVD + + + +DPR+IG WW GFLLC +
Sbjct: 216 GILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALL 275
Query: 359 FLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDV 418
F MF FP+ LPP + + + ++ + + + K + + SS + +
Sbjct: 276 FFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQL 335
Query: 419 RDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVII 478
R +P+ +LSN F + L+ E A+V F F+ K++E QF + S+A+ G+
Sbjct: 336 RVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTA 395
Query: 479 VPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPY 538
+P A +GI LGG ++KKL L A + ++AM+ + VS C+ + +GC++ + G+ +PY
Sbjct: 396 IPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPY 455
Query: 539 --TTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIR 596
+T P + + CN NC C+ + PVCG+DGITY + C AGC NS NL
Sbjct: 456 GNSTAPGSALDPYS---PCNNNCECQTDSFTPVCGADGITYLSACFAGC-NSTNL----- 506
Query: 597 NYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT-CN-TLIPFLVF 654
T C C+ T EN V GKC C + FL
Sbjct: 507 --TGCACLT----------------------TVPAENATVVPGKCPSPGCQEAFLTFLCV 542
Query: 655 LFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCM 714
+ I + I A AQ ++I+ +R+V E + +ALG+ F+LLR L +IP P+ FGA ID+TC+
Sbjct: 543 MCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCL 602
Query: 715 LWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK 761
W CG QG+C Y+ +R++Y +A LK FI W ++
Sbjct: 603 FWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLR 649
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 394 bits (1013), Expect = e-109
Identities = 238/692 (34%), Positives = 358/692 (51%), Gaps = 55/692 (7%)
Query: 65 DSSGHQELKQGPNPL-APSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCLYVV 123
++S QEL++ P +P PS PS + + R F S +CL
Sbjct: 42 ENSQPQELQKPQEPQKSPEPSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRC 101
Query: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183
T FL+ C L Q ++V+G ++ I+T+E+RY +KSS +GL+ S +DI ++ +
Sbjct: 102 NTPGG-FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSL 160
Query: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNST 243
FVS+FG RG +P WLA +I GA +F+LP F S Y++ L D NST
Sbjct: 161 FVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLF----EDTCVTTRNST 216
Query: 244 ATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLA 303
+ C + ++++YV FI Q+L+G G TP+YTLG +LDD+V SSLY+
Sbjct: 217 S------CTSSTSSLSNYLYV--FILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIG 268
Query: 304 IMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLD--QNDPRFIGNWWSGFLLCAIAMFLV 361
Y M LGPA+GY+LGG L+ Y+D D ++DPR++G WW GFLL I + +
Sbjct: 269 TGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSL 328
Query: 362 IFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDL 421
I P FPK LP ++ K++ + Q++ + + FGK ++D
Sbjct: 329 IIPFSCFPKHLP----------------GTAEIQAGKTSQAHQSNSN-ADVKFGKSIKDF 371
Query: 422 PRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPS 481
P A ++ N F+ + LS ++E+ I T F TF+PKFIE+QFG+ +S A+ G +++P
Sbjct: 372 PAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPG 431
Query: 482 AGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTG 541
A +G +LGG+++ K ++ + + K A+ SGV+L CE+ G++ Y
Sbjct: 432 AALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGT 491
Query: 542 PSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTEC 601
L NL CN NC C Y PVCG DG+ YF+PC AGC N + Y C
Sbjct: 492 GEL----GNLIAPCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNP-VAHRKPKVYYNC 545
Query: 602 TCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFI 661
+C++ + IT +T+ E A +GKC+ C L FL FIV
Sbjct: 546 SCIERKTEITS------------TAETFGFE---AKAGKCETHCAKLPIFLCIFFIVIIF 590
Query: 662 TACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QEC 720
T A + LR V +R ALG+QF++LR L IP PI FG ID+TC+LW +C
Sbjct: 591 TFMAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDC 650
Query: 721 GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIF 752
G++G+CW Y+ + ++ K + F
Sbjct: 651 GIKGACWIYDNIKMAHMLVAISVTCKVITMFF 682
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 348 bits (894), Expect = 9e-96
Identities = 220/684 (32%), Positives = 338/684 (49%), Gaps = 68/684 (9%)
Query: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
V + + F++C L Q LM+SGYL S I+T+E+R+ L S SGLL S ++GN ++
Sbjct: 22 VFHNIKLFVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 80
Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
VFVSYFG R RP + G +L+A L LPHFIS PY+ ++P D + Q +
Sbjct: 81 VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN---TSPED-MPQDFKA 136
Query: 243 TATLEPPACPKDSGGNN---------HWVYVALFICAQILIGMGSTPIYTLGPTYLDDNV 293
+ L + P + N H V + AQ L+G+G PI G +Y+DD
Sbjct: 137 SLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFA 196
Query: 294 KKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWS 349
NS LYL I++ + +GP + + LG L++ YVD P + L DPR++G WW
Sbjct: 197 HNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWL 256
Query: 350 GFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKV 409
GFL+ A A+ L P F FPK++P + K++ + + V AV+D K K + S+Q+ +
Sbjct: 257 GFLIAAGAVALAAIPYFFFPKEMP-KEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGES 315
Query: 410 SSMGFG-----------KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKF 458
+ G + ++ PR ++ L + FL V LS S++ TF+PKF
Sbjct: 316 TKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKF 375
Query: 459 IESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCF 518
+E QF I AS A++ G + PS VGIV+GG ++K+L LG L ++ + L
Sbjct: 376 LERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFS 435
Query: 519 STLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-SDGITY 577
LF +GC S + GI + P L L+ SC C C + + PVC S + Y
Sbjct: 436 LPLFFIGCSSHQIAGITHQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPSTRVEY 490
Query: 578 FNPCLAGCVNSGNLSTGIRN----YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNEN 633
PC AGC +S + + N YT C+CV E
Sbjct: 491 ITPCHAGC-SSWVVQDALDNSQVFYTNCSCVV--------------------------EG 523
Query: 634 GYAVSGKCKRTCNTLI-PFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVL 692
++G C TC+ L+ PFL+ + + + + + ++ LR V+ E++ A+G+QF+
Sbjct: 524 NPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMF 583
Query: 693 LRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIF 752
LR LA++P+P+ G+ IDTTC+ W CG + C YN R + GL K I
Sbjct: 584 LRILAWMPSPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVIC 643
Query: 753 IFLAWYSIKYKEDGLQRRRQREFP 776
L ++ ++ + + R P
Sbjct: 644 FALVLAVLRQQDKEARTKESRSSP 667
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 348 bits (894), Expect = 9e-96
Identities = 220/684 (32%), Positives = 338/684 (49%), Gaps = 68/684 (9%)
Query: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
V + + F++C L Q LM+SGYL S I+T+E+R+ L S SGLL S ++GN ++
Sbjct: 44 VFHNIKLFVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 102
Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
VFVSYFG R RP + G +L+A L LPHFIS PY+ ++P D + Q +
Sbjct: 103 VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN---TSPED-MPQDFKA 158
Query: 243 TATLEPPACPKDSGGNN---------HWVYVALFICAQILIGMGSTPIYTLGPTYLDDNV 293
+ L + P + N H V + AQ L+G+G PI G +Y+DD
Sbjct: 159 SLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFA 218
Query: 294 KKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWS 349
NS LYL I++ + +GP + + LG L++ YVD P + L DPR++G WW
Sbjct: 219 HNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWL 278
Query: 350 GFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKV 409
GFL+ A A+ L P F FPK++P + K++ + + V AV+D K K + S+Q+ +
Sbjct: 279 GFLIAAGAVALAAIPYFFFPKEMP-KEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGES 337
Query: 410 SSMGFG-----------KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKF 458
+ G + ++ PR ++ L + FL V LS S++ TF+PKF
Sbjct: 338 TKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKF 397
Query: 459 IESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCF 518
+E QF I AS A++ G + PS VGIV+GG ++K+L LG L ++ + L
Sbjct: 398 LERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFS 457
Query: 519 STLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-SDGITY 577
LF +GC S + GI + P L L+ SC C C + + PVC S + Y
Sbjct: 458 LPLFFIGCSSHQIAGITHQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPSTRVEY 512
Query: 578 FNPCLAGCVNSGNLSTGIRN----YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNEN 633
PC AGC +S + + N YT C+CV E
Sbjct: 513 ITPCHAGC-SSWVVQDALDNSQVFYTNCSCVV--------------------------EG 545
Query: 634 GYAVSGKCKRTCNTLI-PFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVL 692
++G C TC+ L+ PFL+ + + + + + ++ LR V+ E++ A+G+QF+
Sbjct: 546 NPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMF 605
Query: 693 LRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIF 752
LR LA++P+P+ G+ IDTTC+ W CG + C YN R + GL K I
Sbjct: 606 LRILAWMPSPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVIC 665
Query: 753 IFLAWYSIKYKEDGLQRRRQREFP 776
L ++ ++ + + R P
Sbjct: 666 FALVLAVLRQQDKEARTKESRSSP 689
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 340 bits (871), Expect = 4e-93
Identities = 213/669 (31%), Positives = 341/669 (50%), Gaps = 69/669 (10%)
Query: 118 RCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIG 177
RC V + + F++C L Q L+ S Y S +TTIE+R+ L SS SGL+ S +I
Sbjct: 22 RCARSVFGNIKVFVLCQGLLQLCQ-LLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEIS 80
Query: 178 NLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQ---IQELNASAPND 234
N ++++FVSYFG R RP + +GGL +A GA + LPHF+S PYQ N S
Sbjct: 81 NAILIIFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRLQA 140
Query: 235 GLCQGGNSTATLEPPACPKDSGG-----NNHWVYVALFICAQILIGMGSTPIYTLGPTYL 289
LCQ L P C + ++ W L + AQ+L G+G+ PI G +Y+
Sbjct: 141 ELCQ--KHWQDLPPSKCHSTTQNPQKETSSMW---GLMVVAQLLAGIGTVPIQPFGISYV 195
Query: 290 DDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIG 345
DD + NS LY++I++ + GPA GYLLG +++ +VD V+L DPR+IG
Sbjct: 196 DDFSEPSNSPLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIG 255
Query: 346 NWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQA 405
WW G L+ + + L FP F FP+ +P K+ A +D+ + E+A
Sbjct: 256 AWWLGLLISSALLVLTSFPFFFFPRAMPIGAKR-------APATADE------ARKLEEA 302
Query: 406 DKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGI 465
+ S + F ++ P +R+L N F+ V L+ S+++ TF+ KF+E Q+G
Sbjct: 303 KSRGSLVDF---IKRFPCIFLRLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGT 359
Query: 466 PASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVG 525
A+ A+ G + +P+A +G++ GG ++K+ + ++A +S++ LF +G
Sbjct: 360 SAAYANFLIGAVNLPAAALGMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMG 419
Query: 526 CESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGC 585
C + + + P T+ S P + +C +C C + PVCG +GI Y +PC AGC
Sbjct: 420 CSTPTVAEVYPPSTS--SSIHPQ---SPACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGC 474
Query: 586 --VNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR 643
+N + ++ Y C+CV T G S A +G C
Sbjct: 475 SNINMSSATSKQLIYLNCSCV---------TGGSAS----------------AKTGSCPV 509
Query: 644 TC-NTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTP 702
C + L+P + + V+ I + ++ LR V EE+ FA+G+QF+L+R LA++P+P
Sbjct: 510 PCAHFLLPAIFLISFVSLIACISHNPLYMMVLRVVNQEEKSFAIGVQFLLMRLLAWLPSP 569
Query: 703 IYFGAVIDTTCMLWQQEC-GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFI-FLAWYSI 760
+G ID +C+ W C G +G+C Y+ + R Y GL G K +G + + F++W
Sbjct: 570 ALYGLTIDHSCIRWNSLCLGRRGACAYYDNDALRDRYLGLQMGYKALGMLLLCFISWRVK 629
Query: 761 KYKEDGLQR 769
K KE +Q+
Sbjct: 630 KNKEYNVQK 638
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 338 bits (866), Expect = 2e-92
Identities = 227/692 (32%), Positives = 358/692 (51%), Gaps = 71/692 (10%)
Query: 101 LSKTFSVSSALAMLQERRCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSV-ITTIERR 159
L+KT + S++ + RRC + FL + F +AL G + + IT IERR
Sbjct: 7 LNKT-AESASSEKKKTRRC-----NGFKMFLAALSFSYIAKAL--GGIIMKISITQIERR 58
Query: 160 YSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFIS 219
+ + SS +GL+ F+IGNL+V+VFVSYFG + RP + +G LL+ G+ L +LPHF
Sbjct: 59 FDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFM 118
Query: 220 PPYQIQE-------------LNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVAL 266
Y+ + L+ N L G S +E C K+S G++ W+YV +
Sbjct: 119 GYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKD-CVKES-GSHMWIYVFM 176
Query: 267 FICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGF 326
+L G+G TPI LG +Y+DD K+ +SSLYL + +G +GP +G+ LG L
Sbjct: 177 ---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKM 233
Query: 327 YVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKK 382
YVD + + + D R++G WW GFL+ + + P F PK P + +K++K
Sbjct: 234 YVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKN-PNKPQKERKI 292
Query: 383 KFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTF-LFVSLSY 441
S+ + +D + +N + Q K V+ K+V ++ IL+N + +F+ L+
Sbjct: 293 SLSLHVLKTNDDRNQTANLTNQG-KNVT-----KNVTGFFQSLKSILTNPLYVIFLLLTL 346
Query: 442 TAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGAR 501
S+ + +F T++ K++E Q+G AS+A+ G+I +P+ G+ LGG+IIKK KL
Sbjct: 347 LQVSSFIGSF-TYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLV 405
Query: 502 ESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGC 561
AK + + S +S L F + CES ++ G+ + Y S+ CN C C
Sbjct: 406 GIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNC 465
Query: 562 KIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYT---ECTCVQSRQVITPPTVGQR 618
++EPVCG++GITY +PCLAGC + S+GI+ +T C+CV+
Sbjct: 466 DESQWEPVCGNNGITYLSPCLAGCKS----SSGIKKHTVFYNCSCVE------------- 508
Query: 619 SQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFL---FIVTFITACAQPSAIIVTLR 675
V N N A G+C R F +++ I + +A + I++T++
Sbjct: 509 -------VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVK 561
Query: 676 SVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSF 734
V+ E + A+G Q +++RTL I PIYFGA+ID TCM W CG QG+C YN F
Sbjct: 562 IVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFF 621
Query: 735 RFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDG 766
VY GL+ L+F + + +++K K G
Sbjct: 622 GRVYLGLSIALRFPALVLYIVFIFAMKKKFQG 653
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 330 bits (845), Expect = 4e-90
Identities = 218/656 (33%), Positives = 340/656 (51%), Gaps = 70/656 (10%)
Query: 137 LTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPL 196
L+FI + + + S I IERR+ + SS G + F+IGNL+V+VFVSYFG + RP
Sbjct: 36 LSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPK 95
Query: 197 WLAVGGLLIAFGAALFALPHFISPPYQI-QELNASAPNDGLCQGGNSTATLEP------- 248
+ +G ++ G L ALPHF Y+ +E N ++ NST+TL
Sbjct: 96 LIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSE-------NSTSTLSTCLINQIL 148
Query: 249 -----------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKEN 297
C K+SG + W+YV + +L G+G TPI LG +Y+DD K+ +
Sbjct: 149 SLNRASPEIVGKGCLKESG-SYMWIYVFM---GNMLRGIGETPIVPLGLSYIDDFAKEGH 204
Query: 298 SSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLL 353
SSLYL I+ + +GP +G+ LG L YVD + + + D R++G WW FL+
Sbjct: 205 SSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLV 264
Query: 354 CAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMG 413
+ + P F P+ P + +K++K S+ + +D + +N + Q K ++
Sbjct: 265 SGLFSIISSIPFFFLPQT-PNKPQKERKASLSLHVLETNDEKDQTANLTNQG-KNIT--- 319
Query: 414 FGKDVRDLPRAAVRILSNMTF-LFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASI 472
K+V ++ IL+N + +FV L+ S+ + AF T++ K++E Q+G P+S A+I
Sbjct: 320 --KNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAF-TYVFKYVEQQYGQPSSKANI 376
Query: 473 YTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLG 532
GVI +P G+ LGGYIIKK KL AK + + +SL + F + CE+ ++
Sbjct: 377 LLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVA 436
Query: 533 GINIPYTTGPSLTMPHRNLTGS-CNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNL 591
G+ + Y +T HR++ S CN +C C ++EPVCG++GITY +PCLAGC +S
Sbjct: 437 GLTMTYDGNNPVTS-HRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGN 495
Query: 592 STGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNTLI 649
I Y C+C++ V N N A G+C R C
Sbjct: 496 KKPIVFY-NCSCLE--------------------VTGLQNRNYSAHLGECPRDDACTRKF 534
Query: 650 PFLVFLFIVT-FITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAV 708
F V + ++ F +A S +++ ++ V+ E + ALG +++R L I PIYFGA+
Sbjct: 535 YFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGAL 594
Query: 709 IDTTCMLWQ-QECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYK 763
IDTTC+ W CG +GSC YN TSF VY GL++ L+ + + Y++K K
Sbjct: 595 IDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKK 650
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 325 bits (833), Expect = 1e-88
Identities = 203/646 (31%), Positives = 332/646 (51%), Gaps = 67/646 (10%)
Query: 128 RCFLVCMCFLTFIQALMVS-----GYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
RC FL I VS Y++S++T IER++++ +S G + F+IGNL+++
Sbjct: 14 RCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLI 73
Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLC 237
+FVSYFG + RP+ + +G +++ G L +LPHF+ Y+ + N S+ N LC
Sbjct: 74 IFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLC 132
Query: 238 QGGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVK 294
+ T +P C K+ + WVYV + I+ GMG TPI LG +Y++D K
Sbjct: 133 MENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAK 188
Query: 295 KENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSG 350
ENS LY+ ++ +GP +G LL YVD + + + D R++G WW G
Sbjct: 189 FENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFG 248
Query: 351 FLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVS 410
FL+CA L P F P LP K+ +A D++K ++ + ++ + K
Sbjct: 249 FLICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKE 297
Query: 411 SMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNA 470
G KD LP + + LF+ +S +A V I+F+PK++E Q+GI +S+A
Sbjct: 298 KYGITKDF--LPFMKSLSCNPIYMLFILVSVIQFNAFVN-MISFMPKYLEQQYGISSSDA 354
Query: 471 SIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESIN 530
G+ +P +G ++GG I+KK K+ +++A + S + L + F++ CE+ +
Sbjct: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414
Query: 531 LGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGN 590
+ GIN Y P ++ CNV+C C ++PVCG++G++Y + CLAGC S
Sbjct: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS-- 472
Query: 591 LSTGIRN-YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNT 647
+ TGI + C+C+Q+ + N AV G C + C+
Sbjct: 473 IGTGINMVFQNCSCIQT------------------------SGNSSAVLGLCDKGPDCSL 508
Query: 648 LIP-FLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFG 706
++ FL+ + +FI + A +V LR ++ EE+ +G+ R A IP PIYFG
Sbjct: 509 MLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFG 568
Query: 707 AVIDTTCMLW-QQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFI 751
A++D+TC+ W +CG G+C Y+ T+FR++Y GL A L+ F+
Sbjct: 569 ALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFV 614
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 325 bits (833), Expect = 1e-88
Identities = 203/646 (31%), Positives = 332/646 (51%), Gaps = 67/646 (10%)
Query: 128 RCFLVCMCFLTFIQALMVS-----GYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
RC FL I VS Y++S++T IER++++ +S G + F+IGNL+++
Sbjct: 14 RCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLI 73
Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLC 237
+FVSYFG + RP+ + +G +++ G L +LPHF+ Y+ + N S+ N LC
Sbjct: 74 IFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLC 132
Query: 238 QGGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVK 294
+ T +P C K+ + WVYV + I+ GMG TPI LG +Y++D K
Sbjct: 133 MENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAK 188
Query: 295 KENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSG 350
ENS LY+ ++ +GP +G LL YVD + + + D R++G WW G
Sbjct: 189 FENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFG 248
Query: 351 FLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVS 410
FL+CA L P F P LP K+ +A D++K ++ + ++ + K
Sbjct: 249 FLICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKE 297
Query: 411 SMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNA 470
G KD LP + + LF+ +S +A V I+F+PK++E Q+GI +S+A
Sbjct: 298 KYGITKDF--LPFMKSLSCNPIYMLFILVSVIQFNAFVN-MISFMPKYLEQQYGISSSDA 354
Query: 471 SIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESIN 530
G+ +P +G ++GG I+KK K+ +++A + S + L + F++ CE+ +
Sbjct: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414
Query: 531 LGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGN 590
+ GIN Y P ++ CNV+C C ++PVCG++G++Y + CLAGC S
Sbjct: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS-- 472
Query: 591 LSTGIRN-YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNT 647
+ TGI + C+C+Q+ + N AV G C + C+
Sbjct: 473 IGTGINMVFQNCSCIQT------------------------SGNSSAVLGLCDKGPDCSL 508
Query: 648 LIP-FLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFG 706
++ FL+ + +FI + A +V LR ++ EE+ +G+ R A IP PIYFG
Sbjct: 509 MLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFG 568
Query: 707 AVIDTTCMLW-QQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFI 751
A++D+TC+ W +CG G+C Y+ T+FR++Y GL A L+ F+
Sbjct: 569 ALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFV 614
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 318 bits (816), Expect = 1e-86
Identities = 200/670 (29%), Positives = 320/670 (47%), Gaps = 83/670 (12%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
Query: 248 P----------------------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLG 285
P C D+ ++ W+YV L +L G+G TPI LG
Sbjct: 153 PCLLESSSQLPVSVMEKSKSKISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLG 208
Query: 286 PTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDP 341
YLDD ++N++ Y+ + + +GP G+LLG L YVD + + + DP
Sbjct: 209 IAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDP 268
Query: 342 RFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVL 395
+++G WW G+L+ I L P + PK LP ++ +K KF +D +D
Sbjct: 269 QWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD---- 324
Query: 396 KEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFI 455
+ + K+ M RD + + N + + T + + +T+
Sbjct: 325 ---YQTPQGENAKIMEMA-----RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYK 376
Query: 456 PKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSL 515
PK+IE Q+G +S A+ G+I +P+ +GI GG ++KK ++ +AKL + S
Sbjct: 377 PKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGY 436
Query: 516 LCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGI 575
L F +LF +GCE+ ++ G+ + Y ++ R L CN C C ++EP+CG +GI
Sbjct: 437 LLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGI 496
Query: 576 TYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGY 635
TY + CLAGC S I Y CTCV + + N
Sbjct: 497 TYVSACLAGCQTSNRSGKNIIFY-NCTCVG--------------------IAASKSGNSS 535
Query: 636 AVSGKCKRT--C-NTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVL 692
+ G+C++ C + FLV I ++ + I+ LR ++ + + FALG+ +
Sbjct: 536 GIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLA 595
Query: 693 LRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFI 751
+R LA IP P+YFG +IDT+C+ W + CG +GSC Y+ FR +Y GL L V +
Sbjct: 596 IRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSIL 655
Query: 752 FIFLAWYSIK 761
+ +K
Sbjct: 656 LSIAVLFILK 665
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 310 bits (795), Expect = 3e-84
Identities = 194/645 (30%), Positives = 311/645 (48%), Gaps = 83/645 (12%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
Query: 248 P----------------------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLG 285
P C D+ ++ W+YV L +L G+G TPI LG
Sbjct: 153 PCLLESSSQLPVSVMEKSKSKISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLG 208
Query: 286 PTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDP 341
YLDD ++N++ Y+ + + +GP G+LLG L YVD + + + DP
Sbjct: 209 IAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDP 268
Query: 342 RFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVL 395
+++G WW G+L+ I L P + PK LP ++ +K KF +D +D
Sbjct: 269 QWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD---- 324
Query: 396 KEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFI 455
+ + K+ M RD + + N + + T + + +T+
Sbjct: 325 ---YQTPQGENAKIMEMA-----RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYK 376
Query: 456 PKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSL 515
PK+IE Q+G +S A+ G+I +P+ +GI GG ++KK ++ +AKL + S
Sbjct: 377 PKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGY 436
Query: 516 LCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGI 575
L F +LF +GCE+ ++ G+ + Y ++ R L CN C C ++EP+CG +GI
Sbjct: 437 LLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGI 496
Query: 576 TYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGY 635
TY + CLAGC S I Y CTCV + + N
Sbjct: 497 TYVSACLAGCQTSNRSGKNIIFY-NCTCVG--------------------IAASKSGNSS 535
Query: 636 AVSGKCKRT--C-NTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVL 692
+ G+C++ C + FLV I ++ + I+ LR ++ + + FALG+ +
Sbjct: 536 GIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLA 595
Query: 693 LRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRF 736
+R LA IP P+YFG +IDT+C+ W + CG +GSC Y+ FR+
Sbjct: 596 IRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRY 640
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 307 bits (787), Expect = 2e-83
Identities = 207/635 (32%), Positives = 318/635 (50%), Gaps = 56/635 (8%)
Query: 154 TTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFA 213
T IERR+ + SS GL+ F+IGNL V+VFVSYFG + RP + +G L+ G+ L A
Sbjct: 6 TQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMA 65
Query: 214 LPHFISPPYQIQELNASAPNDGLCQG------------GNSTATLEPPACPKDSGGNNHW 261
LPHF Y+ + P++ + + + C K+SG ++ W
Sbjct: 66 LPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG-SHMW 124
Query: 262 VYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGG 321
+YV + +L G+G TPI LG +Y+DD K+ +SSLYL + VMG G ++LG
Sbjct: 125 IYVFM---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGS 181
Query: 322 LLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHK 377
L YVD + + + D R++G WW GFL+ I + P F P L P +K
Sbjct: 182 LFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLP--LNP-NK 238
Query: 378 KKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFV 437
+K++K S+ VLK ++ A+ K+V ++ IL+N ++
Sbjct: 239 PQKERKVSLFL----HVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIF 294
Query: 438 SLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLK 497
+ + A +T+I K +E Q+G AS + GV+ +P+ +G+ GGYIIKK K
Sbjct: 295 VIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFK 354
Query: 498 LGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGS-CN 556
L AKLA + V LL F + CES ++ G+ + Y G S H ++ S CN
Sbjct: 355 LSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTY-DGNSPVRSHVDVPLSYCN 413
Query: 557 VNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVG 616
C C ++EPVCG++GITY +PCLAGC +S I Y C+CV+ +G
Sbjct: 414 SECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFY-NCSCVE--------VIG 464
Query: 617 QRSQLRVVIVKTYLNENGYAVSGKCKR----TCNTLIPFLVFLFIVTFITACAQPSAIIV 672
+ N+N A G+C R T + + F++ + + F+ A S ++
Sbjct: 465 LQ------------NKNYSAHLGECPRDDACTRKSYVYFVIQV-LDAFLCAVGLTSYSVL 511
Query: 673 TLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNV 731
+R V+ E + A+G +++R+L I PIYFGA+IDTTCM W CG +G+C YN
Sbjct: 512 VIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNS 571
Query: 732 TSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDG 766
T +FGL L F + + + + ++ K G
Sbjct: 572 TYLGRAFFGLKVALIFPVLVLLTVFIFVVRKKSHG 606
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 283 bits (724), Expect = 5e-76
Identities = 185/648 (28%), Positives = 299/648 (46%), Gaps = 88/648 (13%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
Query: 248 PPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYV 307
P C +L P+ + +K S + +
Sbjct: 153 P--------------------C--LLESSSQLPVSVM---------EKSKSKISNGCVQT 181
Query: 308 MGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIF 363
+ +GP G+LLG L YVD + + + DP+++G WW G+L+ I L
Sbjct: 182 VAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAV 241
Query: 364 PMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKD 417
P + PK LP ++ +K KF +D +D + + K+ M
Sbjct: 242 PFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD-------YQTPQGENAKIMEMA---- 290
Query: 418 VRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVI 477
RD + + N + + T + + +T+ PK+IE Q+G +S A+ G+I
Sbjct: 291 -RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLI 349
Query: 478 IVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIP 537
+P+ +GI GG ++KK ++ +AKL + S L F +LF +GCE+ ++ G+ +
Sbjct: 350 NIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVS 409
Query: 538 YTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRN 597
Y ++ R L CN C C ++EP+CG +GITY + CLAGC S I
Sbjct: 410 YQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIF 469
Query: 598 YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT--C-NTLIPFLVF 654
Y CTCV + + N + G+C++ C + FLV
Sbjct: 470 Y-NCTCVG--------------------IAASKSGNSSGIVGRCQKDNGCPQMFLYFLVI 508
Query: 655 LFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCM 714
I ++ + I+ LR ++ + + FALG+ + +R LA IP P+YFG +IDT+C+
Sbjct: 509 SVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCL 568
Query: 715 LWQ-QECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK 761
W + CG +GSC Y+ FR +Y GL L V + + +K
Sbjct: 569 KWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILK 616
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 268 bits (686), Expect = 1e-71
Identities = 174/569 (30%), Positives = 270/569 (47%), Gaps = 69/569 (12%)
Query: 229 ASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTY 288
ASAP++G C T H V + AQ L+G+G PI G +Y
Sbjct: 25 ASAPSNGNCSSYTET---------------QHLSVVGIMFVAQTLLGVGGVPIQPFGISY 69
Query: 289 LDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFI 344
+DD NS LYL I++ + +GP + + LG L++ YVD P + L DPR++
Sbjct: 70 IDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWV 129
Query: 345 GNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQ 404
G WW GFL+ A A+ L P F FPK++P + K++ + + V AV+D K K + S+Q
Sbjct: 130 GAWWLGFLIAAGAVALAAIPYFFFPKEMP-KEKRELQFRRKVLAVTDSPARKGKDSPSKQ 188
Query: 405 ADKKVSSMGFG-----------KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFIT 453
+ + + G + ++ PR ++ L + FL V LS S++ T
Sbjct: 189 SPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMAT 248
Query: 454 FIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGV 513
F+PKF+E QF I AS A++ G + PS VGIV+GG ++K+L LG L ++ +
Sbjct: 249 FLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLL 308
Query: 514 SLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-S 572
L LF +GC S + GI + P L L+ SC C C + + PVC S
Sbjct: 309 CLFFSLPLFFIGCSSHQIAGITHQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPS 363
Query: 573 DGITYFNPCLAGCVNSGNLSTGIRN----YTECTCVQSRQVITPPTVGQRSQLRVVIVKT 628
+ Y PC AGC +S + + N YT C+CV
Sbjct: 364 TRVEYITPCHAGC-SSWVVQDALDNSQVFYTNCSCVV----------------------- 399
Query: 629 YLNENGYAVSGKCKRTCNTLI-PFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALG 687
E ++G C TC+ L+ PFL+ + + + + + ++ LR V+ E++ A+G
Sbjct: 400 ---EGNPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVG 456
Query: 688 MQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKF 747
+QF+ LR LA++P+P+ G+ IDTTC+ W CG + C YN R + GL K
Sbjct: 457 IQFMFLRILAWMPSPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKT 516
Query: 748 VGFIFIFLAWYSIKYKEDGLQRRRQREFP 776
I L ++ ++ + + R P
Sbjct: 517 GSVICFALVLAVLRQQDKEARTKESRSSP 545
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 265 bits (678), Expect = 1e-70
Identities = 170/639 (26%), Positives = 290/639 (45%), Gaps = 57/639 (8%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
RCF++ C L Q + V G + I ++ Y LK+ E L +DI + +V +F+++
Sbjct: 106 RCFMIFYCILLICQGV-VFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAF 164
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPN--DGLCQGGNSTAT 245
+G R ++ +W LI G+ L A P I E N + + +C+
Sbjct: 165 YGDR-KKVIWFVASSFLIGLGSLLCAFP-------SINEENKQSKVGIEDICE------E 210
Query: 246 LEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
++ + + SG + Y++ FI Q + G+ P+Y LG T++D+NV ++ +YL I
Sbjct: 211 IKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIA 270
Query: 306 YVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQND--PRFIGNWWSGFLLCAIAMFLVIF 363
+G A+GY+LG L+ + + + N+ P ++ WW FL A+ + +
Sbjct: 271 ECTSMIGYALGYVLGAPLVKVPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLI 330
Query: 364 PMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPR 423
P+ FP +P + K +K+ + D ++ + G +++DL
Sbjct: 331 PLSCFPNNMPGSTRIKARKRKQLHFF----------------DSRLKDLKLGTNIKDLCA 374
Query: 424 AAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAG 483
A ++ N + ++LS E ++ F+P ++E+QF + + A+ G++++P
Sbjct: 375 ALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGA 434
Query: 484 VGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPS 543
+G +LGG I+ L++ + + M+ S +SL+ + V C + GIN Y
Sbjct: 435 LGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGK 494
Query: 544 LTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTC 603
L NLT CN C C Y +CG D I YF+PC AGC S + Y C+C
Sbjct: 495 L----GNLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYS-KAQNQKKMYYNCSC 549
Query: 604 VQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFITA 663
++ +IT G R GKC C L F+ F+F +
Sbjct: 550 IK-EGLITADAEGDFIDAR---------------PGKCDAKCYKLPLFIAFIFSTLIFSG 593
Query: 664 CAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGV 722
+ ++ R V D+ R ALG+ +V+LR IP P F +T+C+L +CG
Sbjct: 594 FSGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGH 653
Query: 723 QGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK 761
G CW YN T F+ G+ K IF +A++ K
Sbjct: 654 TGRCWIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYK 692
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 249 bits (635), Expect = 1e-65
Identities = 160/565 (28%), Positives = 261/565 (46%), Gaps = 82/565 (14%)
Query: 208 GAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEP------------------- 248
G L A+P F Y+ + + S+ NST ++ P
Sbjct: 4 GTLLIAMPQFFMEQYKYERYSPSS---------NSTLSISPCLLESSSQLPVSVMEKSKS 54
Query: 249 ---PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
C D+ ++ W+YV L +L G+G TPI LG YLDD ++N++ Y+ +
Sbjct: 55 KISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCV 110
Query: 306 YVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLV 361
+ +GP G+LLG L YVD + + + DP+++G WW G+L+ I L
Sbjct: 111 QTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLA 170
Query: 362 IFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFG 415
P + PK LP ++ +K KF +D +D + + K+ M
Sbjct: 171 AVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD-------YQTPQGENAKIMEMA-- 221
Query: 416 KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTG 475
RD + + N + + T + + +T+ PK+IE Q+G +S A+ G
Sbjct: 222 ---RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIG 278
Query: 476 VIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGIN 535
+I +P+ +GI GG ++KK ++ +AKL + S L F +LF +GCE+ ++ G+
Sbjct: 279 LINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLT 338
Query: 536 IPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGI 595
+ Y ++ R L CN C C ++EP+CG +GITY + CLAGC S I
Sbjct: 339 VSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNI 398
Query: 596 RNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT--C-NTLIPFL 652
Y CTCV + + N + G+C++ C + FL
Sbjct: 399 IFY-NCTCVG--------------------IAASKSGNSSGIVGRCQKDNGCPQMFLYFL 437
Query: 653 VFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTT 712
V I ++ + I+ LR ++ + + FALG+ + +R LA IP P+YFG +IDT+
Sbjct: 438 VISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTS 497
Query: 713 CMLWQ-QECGVQGSCWEYNVTSFRF 736
C+ W + CG +GSC Y+ FR+
Sbjct: 498 CLKWGFKRCGSRGSCRLYDSNVFRY 522
>gi|194239645 spinster homolog 3 [Homo sapiens]
Length = 512
Score = 49.7 bits (117), Expect = 1e-05
Identities = 73/361 (20%), Positives = 132/361 (36%), Gaps = 103/361 (28%)
Query: 149 LSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFG 208
++ V+ I+ + + + +GLL + F L+ Y G R R ++ G +L+ G
Sbjct: 65 IAGVLLDIQEVFQISDNHAGLLQTVFVSCLLLSAPVFGYLGDRHSRKATMSFG-ILLWSG 123
Query: 209 AALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFI 268
A L + FISP Y W LF
Sbjct: 124 AGLSS--SFISPRYS-------------------------------------W----LFF 140
Query: 269 CAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYV 328
++ ++G GS T+ PT L D ++ + LA+ Y+ +G +GY+LG +
Sbjct: 141 LSRGIVGTGSASYSTIAPTVLGDLFVRDQRTRVLAVFYIFIPVGSGLGYVLGSAV----- 195
Query: 329 DPRNPVHLDQNDPRFIGNW-WSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVD 387
GNW W+ ++ + +I + P PPR + + + +V
Sbjct: 196 ------------TMLTGNWRWALRVMPCLEAVALILLILLVPD--PPRGAAETQGEGAVG 241
Query: 388 AVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAI 447
+ +DVR L + N +F++ +L TA + +
Sbjct: 242 GFRS---------------------SWCEDVRYLGK-------NWSFVWSTLGVTAMAFV 273
Query: 448 VTAFITFIPKFIESQ----------FGIPASNA-SIYTGVIIVPSAGVGIVLGGYIIKKL 496
A + PKF+ F P SN S+ G + + + +G++LG ++
Sbjct: 274 TGALGFWAPKFLLEARVVHGLQPPCFQEPCSNPDSLIFGALTIMTGVIGVILGAEAARRY 333
Query: 497 K 497
K
Sbjct: 334 K 334
>gi|29568105 transmembrane protein with EGF-like and two
follistatin-like domains 1 [Homo sapiens]
Length = 380
Score = 45.8 bits (107), Expect = 2e-04
Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 22/107 (20%)
Query: 556 NVNCGCKI----HEYEPVCGSDGITYFNPCL---AGCVNSGNLSTGIRNYTECTCVQSRQ 608
NV C C I + + PVC SDG +Y NPC A C+ + IR+ CT
Sbjct: 185 NVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQID--IRHLGHCTDTDDTS 242
Query: 609 VI---------TPPTVGQRSQLRVVIVKTYL----NENGYAVSGKCK 642
++ P Q V + ++ N NGY + GKC+
Sbjct: 243 LLGKKDDGLQYRPDVKDASDQREDVYIGNHMPCPENLNGYCIHGKCE 289
Score = 30.4 bits (67), Expect = 7.2
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 557 VNCGCKIH---EYEPVCGSDGITYFNPC 581
+ C C+ Y PVCGS+G TY N C
Sbjct: 95 LKCACQFQCHTNYIPVCGSNGDTYQNEC 122
>gi|185136021 spinster homolog 2 [Homo sapiens]
Length = 549
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/172 (22%), Positives = 64/172 (37%), Gaps = 44/172 (25%)
Query: 149 LSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFG 208
++ V+ I++ + +K +GLL S F +V Y G R R + L+ G I F
Sbjct: 122 VAGVLLDIQQHFGVKDRGAGLLQSVFICSFMVAAPIFGYLGDRFNRKVILSCG---IFFW 178
Query: 209 AALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFI 268
+A+ FI Y W L +
Sbjct: 179 SAVTFSSSFIPQQY-------------------------------------FW----LLV 197
Query: 269 CAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLG 320
++ L+G+G T+ PT + D K +L L++ Y LG +GY+ G
Sbjct: 198 LSRGLVGIGEASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITG 249
>gi|215490102 spinster homolog 1 isoform 3 [Homo sapiens]
Length = 476
Score = 38.9 bits (89), Expect = 0.020
Identities = 42/194 (21%), Positives = 73/194 (37%), Gaps = 45/194 (23%)
Query: 127 SRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVS 186
S + +C++ + M ++ V+ IE+ +++ S SGL+ + F +V+
Sbjct: 58 SALIVAVLCYINLLN-YMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFG 116
Query: 187 YFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATL 246
Y G R R +L GG IAF + + FI
Sbjct: 117 YLGDRYNRK-YLMCGG--IAFWSLVTLGSSFIP--------------------------- 146
Query: 247 EPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMY 306
G + W L + + L+G+G T+ PT + D + S L+I Y
Sbjct: 147 ----------GEHFW----LLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFY 192
Query: 307 VMGALGPAVGYLLG 320
+G +GY+ G
Sbjct: 193 FAIPVGSGLGYIAG 206
>gi|215490096 spinster homolog 1 isoform 1 [Homo sapiens]
Length = 528
Score = 38.9 bits (89), Expect = 0.020
Identities = 42/194 (21%), Positives = 73/194 (37%), Gaps = 45/194 (23%)
Query: 127 SRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVS 186
S + +C++ + M ++ V+ IE+ +++ S SGL+ + F +V+
Sbjct: 58 SALIVAVLCYINLLN-YMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFG 116
Query: 187 YFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATL 246
Y G R R +L GG IAF + + FI
Sbjct: 117 YLGDRYNRK-YLMCGG--IAFWSLVTLGSSFIP--------------------------- 146
Query: 247 EPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMY 306
G + W L + + L+G+G T+ PT + D + S L+I Y
Sbjct: 147 ----------GEHFW----LLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFY 192
Query: 307 VMGALGPAVGYLLG 320
+G +GY+ G
Sbjct: 193 FAIPVGSGLGYIAG 206
>gi|14042968 spinster homolog 1 isoform 1 [Homo sapiens]
Length = 528
Score = 38.9 bits (89), Expect = 0.020
Identities = 42/194 (21%), Positives = 73/194 (37%), Gaps = 45/194 (23%)
Query: 127 SRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVS 186
S + +C++ + M ++ V+ IE+ +++ S SGL+ + F +V+
Sbjct: 58 SALIVAVLCYINLLN-YMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFG 116
Query: 187 YFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATL 246
Y G R R +L GG IAF + + FI
Sbjct: 117 YLGDRYNRK-YLMCGG--IAFWSLVTLGSSFIP--------------------------- 146
Query: 247 EPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMY 306
G + W L + + L+G+G T+ PT + D + S L+I Y
Sbjct: 147 ----------GEHFW----LLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFY 192
Query: 307 VMGALGPAVGYLLG 320
+G +GY+ G
Sbjct: 193 FAIPVGSGLGYIAG 206
>gi|4504619 insulin-like growth factor binding protein 7 [Homo
sapiens]
Length = 282
Score = 37.7 bits (86), Expect = 0.045
Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 559 CGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTEC---TCVQSRQVITPP 613
C CK PVCGSDG TY + C + S G + T+ TC Q ++TPP
Sbjct: 111 CVCKSRY--PVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPP 166
>gi|215490100 spinster homolog 1 isoform 2 [Homo sapiens]
Length = 455
Score = 37.7 bits (86), Expect = 0.045
Identities = 39/172 (22%), Positives = 65/172 (37%), Gaps = 44/172 (25%)
Query: 149 LSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFG 208
++ V+ IE+ +++ S SGL+ + F +V+ Y G R R +L GG IAF
Sbjct: 6 VAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFGYLGDRYNRK-YLMCGG--IAFW 62
Query: 209 AALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFI 268
+ + FI G + W L +
Sbjct: 63 SLVTLGSSFIP-------------------------------------GEHFW----LLL 81
Query: 269 CAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLG 320
+ L+G+G T+ PT + D + S L+I Y +G +GY+ G
Sbjct: 82 LTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFYFAIPVGSGLGYIAG 133
>gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo
sapiens]
Length = 97
Score = 35.8 bits (81), Expect = 0.17
Identities = 17/38 (44%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 566 YEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTC 603
Y+P+CG++ ITY NPC+ CV S IR Y + C
Sbjct: 61 YQPICGTNFITYDNPCIL-CVESLKSHGRIRFYHDGKC 97
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,239,655
Number of Sequences: 37866
Number of extensions: 1627278
Number of successful extensions: 5917
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 5693
Number of HSP's gapped (non-prelim): 164
length of query: 848
length of database: 18,247,518
effective HSP length: 111
effective length of query: 737
effective length of database: 14,044,392
effective search space: 10350716904
effective search space used: 10350716904
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.