Guide to the Human Genome
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Name: SHMT1 Sequence: fasta or formatted (483aa) NCBI GI: 22547186
Description:

serine hydroxymethyltransferase 1 (soluble) isoform 1

Referenced in:

Amino Acid Catabolism
Amino Acid Biosynthesis and Selected Derivatives
Vitamin Pathways, Coenzymes, and 1-Carbon Metabolism

Other entries for this name:
alt prot [444aa] serine hydroxymethyltransferase 1 (soluble) isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.1         44           2
 C cysteine            2.1         10           1
 D aspartate           4.8         23           1
 E glutamate           6.2         30           2
 F phenylalanine       3.5         17           2
 G glycine             8.5         41           2
 H histidine           3.3         16           1
 I isoleucine          4.6         22           2
 K lysine              6.2         30           3
 L leucine            10.6         51           2
 M methionine          2.1         10           1
 N asparagine          4.1         20           2
 P proline             4.6         22           1
 Q glutamine           3.5         17           1
 R arginine            5.0         24           1
 S serine              6.2         30           2
 T threonine           5.2         25           4
 V valine              6.2         30           2
 W tryptophan          0.4          2           1
 Y tyrosine            3.9         19           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   serine hydroxymethyltransferase 1 (soluble) isoform ... 
SHMT1                 0.898   serine hydroxymethyltransferase 1 (soluble) isoform ...
SHMT2                 0.620   serine hydroxymethyltransferase 2 (mitochondrial) [H...
SUPT5H                0.008   suppressor of Ty 5 homolog isoform a 
SUPT5H                0.008   suppressor of Ty 5 homolog isoform a 
SUPT5H                0.008   suppressor of Ty 5 homolog isoform a 
SLC9A1                0.004   solute carrier family 9, isoform A1 
SUPT5H                0.004   suppressor of Ty 5 homolog isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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