Search of human proteins with 22547159

Search of human proteins with 22547159

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens]
         (501 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens]         993   0.0  
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]            56   7e-08
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]            56   7e-08
gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]             56   7e-08
gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]            56   9e-08
gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens]            56   9e-08
gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]            56   9e-08
gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens]             56   9e-08
gi|91825557 kinesin light chain 3 [Homo sapiens]                       54   3e-07
gi|41871960 kinesin-like 8 isoform b [Homo sapiens]                    54   3e-07
gi|41871955 kinesin-like 8 isoform a [Homo sapiens]                    54   3e-07
gi|41871946 kinesin-like 8 isoform a [Homo sapiens]                    54   3e-07
gi|34304360 nephrocystin 3 [Homo sapiens]                              52   1e-06
gi|91208420 bassoon protein [Homo sapiens]                             42   0.001
gi|83415184 transmembrane and tetratricopeptide repeat containin...    42   0.001
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    42   0.001
gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]            41   0.003
gi|169214778 PREDICTED: hypothetical protein LOC284801 [Homo sap...    40   0.004
gi|89058023 PREDICTED: hypothetical protein LOC284801 [Homo sapi...    40   0.004
gi|89057843 PREDICTED: hypothetical protein LOC284801 [Homo sapi...    40   0.004
gi|87162455 hypothetical protein LOC23277 [Homo sapiens]               40   0.006
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    39   0.008
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    39   0.008
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]                    39   0.008
gi|41152235 ubiquitin specific protease 51 [Homo sapiens]              39   0.008
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ...    39   0.008
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ...    39   0.008
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        39   0.008
gi|18959210 WIRE protein [Homo sapiens]                                39   0.008
gi|169171690 PREDICTED: hypothetical protein [Homo sapiens]            39   0.011

>gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens]
          Length = 501

 Score =  993 bits (2568), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MAQPHTTSVPYFARSPAPPPPSRSGAPPQPPATLRPSRRRTRPPRPADRRDAPADCAYLW 60
           MAQPHTTSVPYFARSPAPPPPSRSGAPPQPPATLRPSRRRTRPPRPADRRDAPADCAYLW
Sbjct: 1   MAQPHTTSVPYFARSPAPPPPSRSGAPPQPPATLRPSRRRTRPPRPADRRDAPADCAYLW 60

Query: 61  RILTPRRGRARRSDVGARHRACGRRDVLLSRQGPANPEGARRVVGGQERVWPAVRRGRGG 120
           RILTPRRGRARRSDVGARHRACGRRDVLLSRQGPANPEGARRVVGGQERVWPAVRRGRGG
Sbjct: 61  RILTPRRGRARRSDVGARHRACGRRDVLLSRQGPANPEGARRVVGGQERVWPAVRRGRGG 120

Query: 121 SMFRLLSWSLGRGFLRAAGRRCRGCSARLLPGLAGGPGPEVQVPPSRVAPHGRGPGLLPL 180
           SMFRLLSWSLGRGFLRAAGRRCRGCSARLLPGLAGGPGPEVQVPPSRVAPHGRGPGLLPL
Sbjct: 121 SMFRLLSWSLGRGFLRAAGRRCRGCSARLLPGLAGGPGPEVQVPPSRVAPHGRGPGLLPL 180

Query: 181 LAALAWFSRPAAAEEEEQQGADGAAAEDGADEAEAEIIQLLKRAKLSIMKDEPEEAELIL 240
           LAALAWFSRPAAAEEEEQQGADGAAAEDGADEAEAEIIQLLKRAKLSIMKDEPEEAELIL
Sbjct: 181 LAALAWFSRPAAAEEEEQQGADGAAAEDGADEAEAEIIQLLKRAKLSIMKDEPEEAELIL 240

Query: 241 HDALRLAYQTDNKKAITYTYDLMANLAFIRGQLENAEQLFKATMSYLLGGGMKQEDNAII 300
           HDALRLAYQTDNKKAITYTYDLMANLAFIRGQLENAEQLFKATMSYLLGGGMKQEDNAII
Sbjct: 241 HDALRLAYQTDNKKAITYTYDLMANLAFIRGQLENAEQLFKATMSYLLGGGMKQEDNAII 300

Query: 301 EISLKLASIYAAQNRQEFAVAGYEFCISTLEEKIEREKELAEDIMSVEEKANTHLLLGMC 360
           EISLKLASIYAAQNRQEFAVAGYEFCISTLEEKIEREKELAEDIMSVEEKANTHLLLGMC
Sbjct: 301 EISLKLASIYAAQNRQEFAVAGYEFCISTLEEKIEREKELAEDIMSVEEKANTHLLLGMC 360

Query: 361 LDACARYLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAY 420
           LDACARYLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAY
Sbjct: 361 LDACARYLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAY 420

Query: 421 IYMQRASDLARQINHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKKDEISVQH 480
           IYMQRASDLARQINHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKKDEISVQH
Sbjct: 421 IYMQRASDLARQINHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKKDEISVQH 480

Query: 481 IREELAELSKKSRPLTNSVKL 501
           IREELAELSKKSRPLTNSVKL
Sbjct: 481 IREELAELSKKSRPLTNSVKL 501


>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
          Length = 618

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 37/146 (25%), Positives = 77/146 (52%), Gaps = 9/146 (6%)

Query: 331 EEKIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS--QAQRMYEKALQ 386
           + K +    L  D +++ EK     H  +   L+  A  +L+ K+    +A+ + ++AL+
Sbjct: 268 QNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLA--VLYGKRGKYKEAEPLCKRALE 325

Query: 387 ISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLARQ---INHPELHMVLS 443
           I E++ G+ HP     +++LA     QG+++E   Y QRA ++ +     + P +    +
Sbjct: 326 IREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKN 385

Query: 444 NLAAVLMHRERYTQAKEIYQEALKQA 469
           NLA+  + + ++ QA+ +Y+E L +A
Sbjct: 386 NLASCYLKQGKFKQAETLYKEILTRA 411


>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
          Length = 573

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 37/146 (25%), Positives = 77/146 (52%), Gaps = 9/146 (6%)

Query: 331 EEKIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS--QAQRMYEKALQ 386
           + K +    L  D +++ EK     H  +   L+  A  +L+ K+    +A+ + ++AL+
Sbjct: 268 QNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLA--VLYGKRGKYKEAEPLCKRALE 325

Query: 387 ISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLARQ---INHPELHMVLS 443
           I E++ G+ HP     +++LA     QG+++E   Y QRA ++ +     + P +    +
Sbjct: 326 IREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKN 385

Query: 444 NLAAVLMHRERYTQAKEIYQEALKQA 469
           NLA+  + + ++ QA+ +Y+E L +A
Sbjct: 386 NLASCYLKQGKFKQAETLYKEILTRA 411


>gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]
          Length = 560

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 37/146 (25%), Positives = 77/146 (52%), Gaps = 9/146 (6%)

Query: 331 EEKIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS--QAQRMYEKALQ 386
           + K +    L  D +++ EK     H  +   L+  A  +L+ K+    +A+ + ++AL+
Sbjct: 268 QNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLA--VLYGKRGKYKEAEPLCKRALE 325

Query: 387 ISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLARQ---INHPELHMVLS 443
           I E++ G+ HP     +++LA     QG+++E   Y QRA ++ +     + P +    +
Sbjct: 326 IREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKN 385

Query: 444 NLAAVLMHRERYTQAKEIYQEALKQA 469
           NLA+  + + ++ QA+ +Y+E L +A
Sbjct: 386 NLASCYLKQGKFKQAETLYKEILTRA 411


>gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]
          Length = 622

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 54/222 (24%), Positives = 101/222 (45%), Gaps = 39/222 (17%)

Query: 289 GGGMKQEDNAIIEISLKLASI------YAAQNRQEFAVAGYEFCISTLEE---------- 332
           GGG     +   EI  +L ++      YA+Q R E AV   +  +  LE+          
Sbjct: 181 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 240

Query: 333 --------------KIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS- 375
                         K +    L  D +++ EK     H  +   L+  A  +L+ K+   
Sbjct: 241 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA--VLYGKRGKY 298

Query: 376 -QAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDL-ARQI 433
            +A+ + ++AL+I E++ G+ HP     +S+LA     QG+ +E   Y +RA ++ A ++
Sbjct: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 358

Query: 434 --NHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKK 473
             + P +    +NLA+  + + +Y  A+ +Y+E L +A  K+
Sbjct: 359 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKE 400


>gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens]
          Length = 622

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 54/222 (24%), Positives = 101/222 (45%), Gaps = 39/222 (17%)

Query: 289 GGGMKQEDNAIIEISLKLASI------YAAQNRQEFAVAGYEFCISTLEE---------- 332
           GGG     +   EI  +L ++      YA+Q R E AV   +  +  LE+          
Sbjct: 181 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 240

Query: 333 --------------KIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS- 375
                         K +    L  D +++ EK     H  +   L+  A  +L+ K+   
Sbjct: 241 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA--VLYGKRGKY 298

Query: 376 -QAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDL-ARQI 433
            +A+ + ++AL+I E++ G+ HP     +S+LA     QG+ +E   Y +RA ++ A ++
Sbjct: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 358

Query: 434 --NHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKK 473
             + P +    +NLA+  + + +Y  A+ +Y+E L +A  K+
Sbjct: 359 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKE 400


>gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]
          Length = 545

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 54/222 (24%), Positives = 101/222 (45%), Gaps = 39/222 (17%)

Query: 289 GGGMKQEDNAIIEISLKLASI------YAAQNRQEFAVAGYEFCISTLEE---------- 332
           GGG     +   EI  +L ++      YA+Q R E AV   +  +  LE+          
Sbjct: 104 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 163

Query: 333 --------------KIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS- 375
                         K +    L  D +++ EK     H  +   L+  A  +L+ K+   
Sbjct: 164 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA--VLYGKRGKY 221

Query: 376 -QAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDL-ARQI 433
            +A+ + ++AL+I E++ G+ HP     +S+LA     QG+ +E   Y +RA ++ A ++
Sbjct: 222 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 281

Query: 434 --NHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKK 473
             + P +    +NLA+  + + +Y  A+ +Y+E L +A  K+
Sbjct: 282 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKE 323


>gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens]
          Length = 622

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 54/222 (24%), Positives = 101/222 (45%), Gaps = 39/222 (17%)

Query: 289 GGGMKQEDNAIIEISLKLASI------YAAQNRQEFAVAGYEFCISTLEE---------- 332
           GGG     +   EI  +L ++      YA+Q R E AV   +  +  LE+          
Sbjct: 181 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 240

Query: 333 --------------KIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS- 375
                         K +    L  D +++ EK     H  +   L+  A  +L+ K+   
Sbjct: 241 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA--VLYGKRGKY 298

Query: 376 -QAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDL-ARQI 433
            +A+ + ++AL+I E++ G+ HP     +S+LA     QG+ +E   Y +RA ++ A ++
Sbjct: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 358

Query: 434 --NHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKK 473
             + P +    +NLA+  + + +Y  A+ +Y+E L +A  K+
Sbjct: 359 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKE 400


>gi|91825557 kinesin light chain 3 [Homo sapiens]
          Length = 504

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 36/148 (24%), Positives = 75/148 (50%), Gaps = 9/148 (6%)

Query: 331 EEKIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS--QAQRMYEKALQ 386
           + K +   +L  D + + E+     H  +   L+  A  +L+ K+    +A+ + ++AL+
Sbjct: 262 QNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLA--VLYGKRGRYREAEPLCQRALE 319

Query: 387 ISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLARQI---NHPELHMVLS 443
           I E++ G  HP     +++LA     QG+F++   +  RA  +   +   + P +    +
Sbjct: 320 IREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKN 379

Query: 444 NLAAVLMHRERYTQAKEIYQEALKQAKL 471
           NLA+  + + +Y QA+E+Y+E L +  L
Sbjct: 380 NLASAYLKQNKYQQAEELYKEILHKEDL 407



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 42/160 (26%), Positives = 70/160 (43%), Gaps = 19/160 (11%)

Query: 310 YAAQNRQEFAVAGYEFCISTLEEKIEREKELAEDIMSVEEKANTHLLLGMCLDACARYLL 369
           YA Q R E AV     C   LE+ +ER               + H  +   L+  A    
Sbjct: 217 YAGQGRYEVAVP---LCRQALED-LERSS------------GHCHPDVATMLNILALVYR 260

Query: 370 FSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDL 429
              +  +A  +   ALQI E+  G  HP     +++LA     +GR+ EA    QRA ++
Sbjct: 261 DQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEI 320

Query: 430 ARQI---NHPELHMVLSNLAAVLMHRERYTQAKEIYQEAL 466
             ++   +HP++   L+NLA +  ++ ++   +  Y  AL
Sbjct: 321 REKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARAL 360


>gi|41871960 kinesin-like 8 isoform b [Homo sapiens]
          Length = 637

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 43/173 (24%), Positives = 86/173 (49%), Gaps = 15/173 (8%)

Query: 331 EEKIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS--QAQRMYEKALQ 386
           + K +    L  D +S+ E      H  +   L+  A  +L+ K+    +A+ + ++AL+
Sbjct: 284 QNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLA--VLYGKRGKYKEAEPLCQRALE 341

Query: 387 ISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLAR-QI--NHPELHMVLS 443
           I E++ G  HP     +++LA     QG+++    Y QRA  +   Q+  ++P +    +
Sbjct: 342 IREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKN 401

Query: 444 NLAAVLMHRERYTQAKEIYQEALKQAKLKK------DEISVQHIREELAELSK 490
           NLA+  + + +Y +A+ +Y+E L +A +++      D   +    EE  E+SK
Sbjct: 402 NLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSK 454


>gi|41871955 kinesin-like 8 isoform a [Homo sapiens]
          Length = 619

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 43/173 (24%), Positives = 86/173 (49%), Gaps = 15/173 (8%)

Query: 331 EEKIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS--QAQRMYEKALQ 386
           + K +    L  D +S+ E      H  +   L+  A  +L+ K+    +A+ + ++AL+
Sbjct: 266 QNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLA--VLYGKRGKYKEAEPLCQRALE 323

Query: 387 ISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLAR-QI--NHPELHMVLS 443
           I E++ G  HP     +++LA     QG+++    Y QRA  +   Q+  ++P +    +
Sbjct: 324 IREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKN 383

Query: 444 NLAAVLMHRERYTQAKEIYQEALKQAKLKK------DEISVQHIREELAELSK 490
           NLA+  + + +Y +A+ +Y+E L +A +++      D   +    EE  E+SK
Sbjct: 384 NLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSK 436


>gi|41871946 kinesin-like 8 isoform a [Homo sapiens]
          Length = 619

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 43/173 (24%), Positives = 86/173 (49%), Gaps = 15/173 (8%)

Query: 331 EEKIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS--QAQRMYEKALQ 386
           + K +    L  D +S+ E      H  +   L+  A  +L+ K+    +A+ + ++AL+
Sbjct: 266 QNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLA--VLYGKRGKYKEAEPLCQRALE 323

Query: 387 ISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLAR-QI--NHPELHMVLS 443
           I E++ G  HP     +++LA     QG+++    Y QRA  +   Q+  ++P +    +
Sbjct: 324 IREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKN 383

Query: 444 NLAAVLMHRERYTQAKEIYQEALKQAKLKK------DEISVQHIREELAELSK 490
           NLA+  + + +Y +A+ +Y+E L +A +++      D   +    EE  E+SK
Sbjct: 384 NLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSK 436


>gi|34304360 nephrocystin 3 [Homo sapiens]
          Length = 1330

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 59/262 (22%), Positives = 105/262 (40%), Gaps = 39/262 (14%)

Query: 224  AKLSIMKDEPEEAELILHDALRLAYQTDNKKAITYTYDLMANLAFIRGQLENAEQLFKAT 283
            A L   +++ E+AE     + ++  +   KK   Y + L+   A          QL + T
Sbjct: 1034 ATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRAL---------QLEELT 1084

Query: 284  MSYLLGGGMKQEDNAIIEISLKLASIYAAQNRQEFAVAGYEFCISTLEEKIEREKELAED 343
            +      G    DNA      +L  +Y  QN  E           T ++ ++R  E+ E 
Sbjct: 1085 L------GKDTPDNA--RTLNELGVLYYLQNNLE-----------TADQFLKRSLEMRER 1125

Query: 344  IMSVEEKANTHLLLGMCLDACARYLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLM 403
            ++  +     H      L+  A      KQ  +A+ +YE+AL I        HP     +
Sbjct: 1126 VLGPD-----HPDCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTV 1180

Query: 404  SDLATTLDAQGRFDEAYIYMQRASDLARQI---NHPELHMVLSNLAAVLMHRERYTQAKE 460
              LA      G+ D+A    + A ++ ++     HP +   L NLA +    +++ +A  
Sbjct: 1181 KHLAILYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALP 1240

Query: 461  IYQEALKQAKLKKDEISVQHIR 482
            +Y+ AL   K+ +D +   H R
Sbjct: 1241 LYERAL---KIYEDSLGRMHPR 1259



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 46/209 (22%), Positives = 88/209 (42%), Gaps = 22/209 (10%)

Query: 275  NAEQLFKATMSYLLGGGMKQEDNAIIEISLKLASIYAAQNRQEFAVAGYEFCISTLEEKI 334
            NAEQL+K  +                E+   LA++Y  QN+ E A    +      ++ I
Sbjct: 1003 NAEQLYKQALEISENAYGADHPYTARELEA-LATLYQKQNKYEQAEHFRKKSFKIHQKAI 1061

Query: 335  EREKEL------AEDIMSVEEKANTHLLLGMCLDACARYL-------LFSKQPSQAQRMY 381
            +++  L          + +EE     L LG      AR L               A +  
Sbjct: 1062 KKKGNLYGFALLRRRALQLEE-----LTLGKDTPDNARTLNELGVLYYLQNNLETADQFL 1116

Query: 382  EKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLARQI---NHPEL 438
            +++L++ E + G  HP     +++LA   + + ++D+A    +RA D+ R+    +HP L
Sbjct: 1117 KRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSL 1176

Query: 439  HMVLSNLAAVLMHRERYTQAKEIYQEALK 467
               + +LA +     +  +A  +Y+ A++
Sbjct: 1177 AYTVKHLAILYKKMGKLDKAVPLYELAVE 1205



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 10/128 (7%)

Query: 334  IEREKELAEDIMSVEEKANTHLLLGMCLDACARYLLFSKQPSQAQRMYEKALQISEEIQG 393
            ++R  E+ E  +  +     H  +   L   A   +  K+   A+++Y++AL+ISE   G
Sbjct: 966  LQRSLEIRETALDPD-----HPRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAYG 1020

Query: 394  ERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLARQINHPELHMVLSNLAAVLMHRE 453
              HP T   +  LAT    Q ++++A  + +++  +     H +      NL    + R 
Sbjct: 1021 ADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKI-----HQKAIKKKGNLYGFALLRR 1075

Query: 454  RYTQAKEI 461
            R  Q +E+
Sbjct: 1076 RALQLEEL 1083



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 22/97 (22%), Positives = 48/97 (49%), Gaps = 4/97 (4%)

Query: 375  SQAQRMYEKALQISEEIQGERHPQTIV-LMSDLATTLDAQGRFDEAYIYMQRASDL---A 430
            + A   ++   Q  +  +GE +   +  L   L   L   G   +A + +QR+ ++   A
Sbjct: 917  AMATEYFDSLKQYEKNCEGEDNMSCLADLYETLGRFLKDLGLLSQAIVPLQRSLEIRETA 976

Query: 431  RQINHPELHMVLSNLAAVLMHRERYTQAKEIYQEALK 467
               +HP +   L  LA+V +  +++  A+++Y++AL+
Sbjct: 977  LDPDHPRVAQSLHQLASVYVQWKKFGNAEQLYKQALE 1013



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 18/58 (31%), Positives = 32/58 (55%)

Query: 372  KQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDL 429
            K+  +A  +YE+AL+I E+  G  HP+    + +LA      G F++A    +RA ++
Sbjct: 1233 KKHVEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYKRAMEI 1290



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 5/104 (4%)

Query: 375  SQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEA-YIYMQ--RASDLAR 431
            SQA    +++L+I E      HP+    +  LA+      +F  A  +Y Q    S+ A 
Sbjct: 960  SQAIVPLQRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAY 1019

Query: 432  QINHPELHMVLSNLAAVLMHRERYTQAKEIYQEALK--QAKLKK 473
              +HP     L  LA +   + +Y QA+   +++ K  Q  +KK
Sbjct: 1020 GADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKK 1063


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 63/227 (27%), Positives = 86/227 (37%), Gaps = 32/227 (14%)

Query: 7   TSVPYFARSPAPPPPSRSGAPPQPPATLRPSRRRTRPPRPADRRDAPADCAYLWRILTPR 66
           TSVP  A++ APP   R    PQPP   +PS    RPP      +APA  A     +   
Sbjct: 285 TSVPGPAQAAAPPEVGR--VSPQPPQPTKPSTAEPRPP----AGEAPAKSA---TAVPAG 335

Query: 67  RGRARRSDVGARHRACGRRDVLLSRQGPANPEGARRVVGGQERVWPAVRRGRGGSMFRLL 126
            G   ++  G   +  G    LL++              GQ    PA  +G    +F   
Sbjct: 336 LGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQ----PAPSKGTPKIVFNDA 391

Query: 127 SWSLGRGFLRAAGRRCRGCSARLLPGLAGGPGPEVQVPPSRVAPHGRGPGLLPLLAALAW 186
           S        + AG +  G      PG    PG + + P +R+ P G GPG LP       
Sbjct: 392 S--------KEAGPKPLGSG----PGPGPAPGAKTE-PGARMGP-GSGPGALPKTGGTTS 437

Query: 187 FSRPAAAEEEEQQGADGAAAEDGADEAEAEIIQLLKRAKLSIMKDEP 233
                A    E Q A  AAA+      E  I  L  +A+L++    P
Sbjct: 438 PKHGRA----EHQAASKAAAKPKTMPKERAICPLC-QAELNVGSKSP 479


>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
           [Homo sapiens]
          Length = 774

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 13/104 (12%)

Query: 371 SKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLA 430
           ++  ++A+  Y++ALQ+        HPQ    + +L   L +Q + +EA   ++ +    
Sbjct: 419 TRDTAEAKMYYQRALQL--------HPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYG 470

Query: 431 RQINHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKKD 474
                PE     S+LA++L  +ER+ +A+EIYQ  +K      D
Sbjct: 471 -----PEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSD 509



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 67/280 (23%), Positives = 119/280 (42%), Gaps = 34/280 (12%)

Query: 227 SIMKDEPEEAELILHDALRLAYQTDNKKAITYTYDLMANLAFIRGQLENAEQLFKATMSY 286
           + +KD+    E I H    L     +  A+     L  + A  +   + A QL       
Sbjct: 383 NFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTRDTAEAKMYYQRALQLHPQHNRA 442

Query: 287 L--LGGGMKQEDNAIIEISLKLASIYAAQNRQEFAVAGYEFCISTLEEKIEREKELAE-- 342
           L  LG  +K ++     I+L   SI   +   EFA A Y    S L E+ ER KE  E  
Sbjct: 443 LFNLGNLLKSQEKKEEAITLLKDSI---KYGPEFADA-YSSLASLLAEQ-ERFKEAEEIY 497

Query: 343 --DIMSVEEKANTHLLLGMCLDACARYLLFSKQPSQAQRMYEKALQISEEIQGERHPQTI 400
              I +  + ++ H   G+       +L+ +  P +A   Y++A+++S        P   
Sbjct: 498 QTGIKNCPDSSDLHNNYGV-------FLVDTGLPEKAVAHYQQAIKLS--------PSHH 542

Query: 401 VLMSDLATTLDAQGRFDEAYIYMQRASDLARQINHPELHMVLSNLAAVLMHRERYTQAKE 460
           V M +L     + G    A  + +RA  +A +        +LS L A+  +  RY +A +
Sbjct: 543 VAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAE------ILSPLGALYYNTGRYEEALQ 596

Query: 461 IYQEALK-QAKLKKDEISVQHIREELAELSKKSRPLTNSV 499
           IYQEA   Q   ++  +++  +   + + +K++  +TN +
Sbjct: 597 IYQEAAALQPSQRELRLALAQVLAVMGQ-TKEAEKMTNHI 635


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 20/40 (50%), Positives = 22/40 (55%), Gaps = 4/40 (10%)

Query: 14  RSPAPPPPSRSGAPPQPPATLRPSRRRTRPPRPADRRDAP 53
           ++P PPPPSR G PP PP    P      PP PA  R AP
Sbjct: 275 QAPPPPPPSRGGPPPPPP----PPHNSGPPPPPARGRGAP 310



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 41/138 (29%), Positives = 56/138 (40%), Gaps = 16/138 (11%)

Query: 1   MAQPHTTSVPYFARS-PAPPPPSRSG----APPQPPATLRPSRRRTRPPRPAD-RRDAPA 54
           M  P   ++P  A S P PPPPS  G    APP PP    P      P  P+D     P 
Sbjct: 342 MYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPT 401

Query: 55  DCAYLWRILTPRR--GRARRSDVGARHRACGRRDVLLS--RQGPANPEGARRVVGGQERV 110
                  +L   R   + ++ +  +R  +C  RD LL   RQG       + V  GQE  
Sbjct: 402 TAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQ----LKSVADGQEST 457

Query: 111 --WPAVRRGRGGSMFRLL 126
              PA   G  G++  ++
Sbjct: 458 PPTPAPTSGIVGALMEVM 475



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 24/63 (38%), Positives = 26/63 (41%), Gaps = 12/63 (19%)

Query: 4   PHTTSVPYF-ARSPAPPPPSRSGAP---PQPPATLRPS--------RRRTRPPRPADRRD 51
           PH +  P   AR    PPP  S AP   P PP   RPS         R   PP PA    
Sbjct: 294 PHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSS 353

Query: 52  APA 54
           AP+
Sbjct: 354 APS 356


>gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 251

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 44/148 (29%), Positives = 50/148 (33%), Gaps = 19/148 (12%)

Query: 4   PHTTSVPYFARSPAPP-------------PPSRSGAPPQPPATLRPSR--RRTRPPRPAD 48
           P T +    ARSP PP             P   +GA P PPA   P+R   R   P P  
Sbjct: 27  PGTRTPATPARSPRPPLCAPRPAPGRAQSPVPAAGAVPSPPAAAHPARPALRGETPAPGR 86

Query: 49  RRDAPADCAYLWRILTPRRGRARRSDVGARHRACGRRDVLLSRQGPANPEGARRVVGGQE 108
           R  A         +  P   R  R     R R         SR+ P  P G RR      
Sbjct: 87  RGRATTRGEVQPSVRPPLSHRPLRGGGMGRGRPGKGPPPNPSRRLPPAPPGGRRTWLSAL 146

Query: 109 RVWPAV----RRGRGGSMFRLLSWSLGR 132
              PA     RR R   +FR   W  GR
Sbjct: 147 ATGPAAGGAGRRRRSPPVFRAADWGFGR 174


>gi|169214778 PREDICTED: hypothetical protein LOC284801 [Homo
           sapiens]
          Length = 228

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 58/181 (32%), Positives = 74/181 (40%), Gaps = 24/181 (13%)

Query: 12  FARSPAPPPPSRSGAPPQPPATLRPSRRRTRPPRPADRRDAPADCAYLWRILTPRRGRAR 71
           F  +  PPPP  S  P   P+  R  RRR R       R A      +    +P  G  R
Sbjct: 33  FRPASDPPPPRVSSPPAPLPSRDRCGRRRLRGTWSG--RLALGKRPTVGARRSPGAGPGR 90

Query: 72  RSDVGARHRACGRRDVLLSRQGPA-NPEG-ARRVVGGQERVWPAVRRGRGGSMFRLLSWS 129
           R D        G   V +   GP    +G  R+V+ G E + PA + GR G+   L+S +
Sbjct: 91  RMDENHERCGPGVEFVAVVASGPRWRDQGLVRQVLVGAEGL-PASQAGRRGT--ALVSVA 147

Query: 130 LG-RGFLRAAGRRCRGCSARLLP-----GLAGG-----PGPEVQVPPSRVAPHGRGPGLL 178
           +G RG +    R C     R LP     GL G      PGP +  PPS   P  R   LL
Sbjct: 148 VGSRGRVFLVARPC----LRFLPQPPLCGLPGALALAVPGPCLSAPPS--PPAARRSSLL 201

Query: 179 P 179
           P
Sbjct: 202 P 202


>gi|89058023 PREDICTED: hypothetical protein LOC284801 [Homo
           sapiens]
          Length = 228

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 58/181 (32%), Positives = 74/181 (40%), Gaps = 24/181 (13%)

Query: 12  FARSPAPPPPSRSGAPPQPPATLRPSRRRTRPPRPADRRDAPADCAYLWRILTPRRGRAR 71
           F  +  PPPP  S  P   P+  R  RRR R       R A      +    +P  G  R
Sbjct: 33  FRPASDPPPPRVSSPPAPLPSRDRCGRRRLRGTWSG--RLALGKRPTVGARRSPGAGPGR 90

Query: 72  RSDVGARHRACGRRDVLLSRQGPA-NPEG-ARRVVGGQERVWPAVRRGRGGSMFRLLSWS 129
           R D        G   V +   GP    +G  R+V+ G E + PA + GR G+   L+S +
Sbjct: 91  RMDENHERCGPGVEFVAVVASGPRWRDQGLVRQVLVGAEGL-PASQAGRRGT--ALVSVA 147

Query: 130 LG-RGFLRAAGRRCRGCSARLLP-----GLAGG-----PGPEVQVPPSRVAPHGRGPGLL 178
           +G RG +    R C     R LP     GL G      PGP +  PPS   P  R   LL
Sbjct: 148 VGSRGRVFLVARPC----LRFLPQPPLCGLPGALALAVPGPCLSAPPS--PPAARRSSLL 201

Query: 179 P 179
           P
Sbjct: 202 P 202


>gi|89057843 PREDICTED: hypothetical protein LOC284801 [Homo
           sapiens]
          Length = 228

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 58/181 (32%), Positives = 74/181 (40%), Gaps = 24/181 (13%)

Query: 12  FARSPAPPPPSRSGAPPQPPATLRPSRRRTRPPRPADRRDAPADCAYLWRILTPRRGRAR 71
           F  +  PPPP  S  P   P+  R  RRR R       R A      +    +P  G  R
Sbjct: 33  FRPASDPPPPRVSSPPAPLPSRDRCGRRRLRGTWSG--RLALGKRPTVGARRSPGAGPGR 90

Query: 72  RSDVGARHRACGRRDVLLSRQGPA-NPEG-ARRVVGGQERVWPAVRRGRGGSMFRLLSWS 129
           R D        G   V +   GP    +G  R+V+ G E + PA + GR G+   L+S +
Sbjct: 91  RMDENHERCGPGVEFVAVVASGPRWRDQGLVRQVLVGAEGL-PASQAGRRGT--ALVSVA 147

Query: 130 LG-RGFLRAAGRRCRGCSARLLP-----GLAGG-----PGPEVQVPPSRVAPHGRGPGLL 178
           +G RG +    R C     R LP     GL G      PGP +  PPS   P  R   LL
Sbjct: 148 VGSRGRVFLVARPC----LRFLPQPPLCGLPGALALAVPGPCLSAPPS--PPAARRSSLL 201

Query: 179 P 179
           P
Sbjct: 202 P 202


>gi|87162455 hypothetical protein LOC23277 [Homo sapiens]
          Length = 1309

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 3/116 (2%)

Query: 354  HLLLGMCLDACARYLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQ 413
            H+    CL   AR        ++A    +KA+ +SE + G  HP TI     LA    A 
Sbjct: 1016 HVETCACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFAS 1075

Query: 414  GRFDEAYIYMQRASDLARQI---NHPELHMVLSNLAAVLMHRERYTQAKEIYQEAL 466
             +   A   + RA  L   +   +HPE+ ++ +N+  VL     Y  +    + AL
Sbjct: 1076 SQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENAL 1131


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 4/54 (7%)

Query: 4   PHTTSVPYFARSPAPPPPSRS----GAPPQPPATLRPSRRRTRPPRPADRRDAP 53
           P ++S P+  R P PP PSR+      PP PP   RPS  R   P P  + + P
Sbjct: 239 PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKP 292



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 34/108 (31%), Positives = 40/108 (37%), Gaps = 21/108 (19%)

Query: 16  PAPPPPSRSGAPPQPPA------TLRPSRRR-----TRPPRPADRRDAPADCAYLWRILT 64
           P PPPPSR G PP PP+      T R  +R      + PP P+  R  P       R   
Sbjct: 308 PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPP 367

Query: 65  PRRGRARRSDV----------GARHRACGRRDVLLSRQGPANPEGARR 102
           P R    RS            G+  RA      L SR G  +P    R
Sbjct: 368 PVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR 415



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 4   PHTTSVPYFARSPAPPPPSRSGAPPQPPATLRPSRRRTRPPRP 46
           P   + P   R   PPPP ++  PP  P+T RPS     PP P
Sbjct: 269 PPVGNRPSIHREAVPPPPPQNNKPP-VPSTPRPSASSQAPPPP 310



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 20/57 (35%), Positives = 23/57 (40%), Gaps = 9/57 (15%)

Query: 4   PHTTSVPYFARSPAPPPP-------SRSGAPPQPPATLRPSRRRTRPPRPADRRDAP 53
           P T S     + P PPPP        R   PP PP   +P    T  PRP+    AP
Sbjct: 253 PPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST--PRPSASSQAP 307


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 4/54 (7%)

Query: 4   PHTTSVPYFARSPAPPPPSRS----GAPPQPPATLRPSRRRTRPPRPADRRDAP 53
           P ++S P+  R P PP PSR+      PP PP   RPS  R   P P  + + P
Sbjct: 239 PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKP 292



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 34/108 (31%), Positives = 40/108 (37%), Gaps = 21/108 (19%)

Query: 16  PAPPPPSRSGAPPQPPA------TLRPSRRR-----TRPPRPADRRDAPADCAYLWRILT 64
           P PPPPSR G PP PP+      T R  +R      + PP P+  R  P       R   
Sbjct: 308 PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPP 367

Query: 65  PRRGRARRSDV----------GARHRACGRRDVLLSRQGPANPEGARR 102
           P R    RS            G+  RA      L SR G  +P    R
Sbjct: 368 PVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR 415



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 4   PHTTSVPYFARSPAPPPPSRSGAPPQPPATLRPSRRRTRPPRP 46
           P   + P   R   PPPP ++  PP  P+T RPS     PP P
Sbjct: 269 PPVGNRPSIHREAVPPPPPQNNKPP-VPSTPRPSASSQAPPPP 310



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 20/57 (35%), Positives = 23/57 (40%), Gaps = 9/57 (15%)

Query: 4   PHTTSVPYFARSPAPPPP-------SRSGAPPQPPATLRPSRRRTRPPRPADRRDAP 53
           P T S     + P PPPP        R   PP PP   +P    T  PRP+    AP
Sbjct: 253 PPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST--PRPSASSQAP 307


>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
          Length = 248

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 51/200 (25%), Positives = 90/200 (45%), Gaps = 26/200 (13%)

Query: 312 AQNRQEFAVAGYEFCISTLEEKIEREKE-LAEDIMSVEE--KANTHLLLGM------CLD 362
           A+ + E  VA     I  +EE+++R +E LA  +  +EE  KA      GM       L 
Sbjct: 41  AREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALK 100

Query: 363 ACARYLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIY 422
              +  L   Q  +A+ + E+A +  EE+  +     +++  DL  T +       A + 
Sbjct: 101 DEEKMELQEIQLKEAKHIAEEADRKYEEVARK----LVIIEGDLERTEE------RAELA 150

Query: 423 MQRASDLARQINHPELHMVLSNLAAVLMHRERYTQAKEIYQEALK--QAKLKKDEISVQH 480
             + S+L       EL  V +NL ++    E+Y+Q ++ Y+E +K    KLK+ E   + 
Sbjct: 151 ESKCSELEE-----ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEF 205

Query: 481 IREELAELSKKSRPLTNSVK 500
               +A+L K    L + +K
Sbjct: 206 AERSVAKLEKTIDDLEDKLK 225


>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
          Length = 711

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 25/61 (40%), Positives = 27/61 (44%), Gaps = 8/61 (13%)

Query: 3   QPHTTSVPYFARSPAPPPPSRSGAPPQPPATLRP-------SRRRTRP-PRPADRRDAPA 54
           QP   S      S  PPPP+R   PP PP    P       SRRR+RP  RP  RR    
Sbjct: 109 QPRARSRSQPGLSAPPPPPARPPPPPPPPPPPAPRPRAWRGSRRRSRPGSRPQTRRSCSG 168

Query: 55  D 55
           D
Sbjct: 169 D 169



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 34/104 (32%), Positives = 40/104 (38%), Gaps = 26/104 (25%)

Query: 5   HTTSVPYFARS---PAPPPPSRS------GAPPQPPATLRPSRRRTRPPRPADRRDAPAD 55
           H++S P   R    P P P +RS       APP PPA         RPP P      PA 
Sbjct: 92  HSSSSPVCPRRKPRPRPQPRARSRSQPGLSAPPPPPA---------RPPPPPPPPPPPAP 142

Query: 56  CAYLWRILTPRRGRARRSDVGARHRACGRRDVLLSRQGPANPEG 99
               W      RG  RRS  G+R +   RR       G  +P G
Sbjct: 143 RPRAW------RGSRRRSRPGSRPQT--RRSCSGDLDGSGDPGG 178


>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 54/264 (20%), Positives = 111/264 (42%), Gaps = 42/264 (15%)

Query: 258 YTYDLMANLAFIRGQLENAEQLFKAT--MSYLLGGGMKQEDNAIIEISLKLASI--YAAQ 313
           Y Y+L   +A +  Q E   +  K     S +L   MK ++  + +   KL  I  +  +
Sbjct: 326 YIYELQKRIAEMETQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEE 385

Query: 314 NRQEFAVAGYEFC------------ISTLEEKIEREKELAEDIMSVEEKANTHLLLGMCL 361
           N+++F     E                 LE++++++KE  E+  S+  K+N      +  
Sbjct: 386 NKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSN-----NIIN 440

Query: 362 DACARYLLFSKQPSQAQRMYEKAL----QISEEIQGERHPQTIVLMSDLATTLDAQGRFD 417
           +   R     K+  + ++  ++ +    Q ++ +Q E+  +   LM    +  +A+ + D
Sbjct: 441 ETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMD 500

Query: 418 ----EAYIYMQRASDLARQINHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKK 473
               E  IY+ R +    Q+   +  ++    AA    +ER    ++I      + KL +
Sbjct: 501 VAQSELDIYLSRHNTAVSQLTKAKEALI----AASETLKERKAAIRDI------EGKLPQ 550

Query: 474 DEISVQHIREELAELSKKSRPLTN 497
            E   Q ++E+  EL K ++  TN
Sbjct: 551 TE---QELKEKEKELQKLTQEETN 571


>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 54/264 (20%), Positives = 111/264 (42%), Gaps = 42/264 (15%)

Query: 258 YTYDLMANLAFIRGQLENAEQLFKAT--MSYLLGGGMKQEDNAIIEISLKLASI--YAAQ 313
           Y Y+L   +A +  Q E   +  K     S +L   MK ++  + +   KL  I  +  +
Sbjct: 326 YIYELQKRIAEMETQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEE 385

Query: 314 NRQEFAVAGYEFC------------ISTLEEKIEREKELAEDIMSVEEKANTHLLLGMCL 361
           N+++F     E                 LE++++++KE  E+  S+  K+N      +  
Sbjct: 386 NKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSN-----NIIN 440

Query: 362 DACARYLLFSKQPSQAQRMYEKAL----QISEEIQGERHPQTIVLMSDLATTLDAQGRFD 417
           +   R     K+  + ++  ++ +    Q ++ +Q E+  +   LM    +  +A+ + D
Sbjct: 441 ETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMD 500

Query: 418 ----EAYIYMQRASDLARQINHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKK 473
               E  IY+ R +    Q+   +  ++    AA    +ER    ++I      + KL +
Sbjct: 501 VAQSELDIYLSRHNTAVSQLTKAKEALI----AASETLKERKAAIRDI------EGKLPQ 550

Query: 474 DEISVQHIREELAELSKKSRPLTN 497
            E   Q ++E+  EL K ++  TN
Sbjct: 551 TE---QELKEKEKELQKLTQEETN 571


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 50/186 (26%), Positives = 67/186 (36%), Gaps = 17/186 (9%)

Query: 13   ARSPAPPPPSRSGAPPQPPATLRPSRRRTRP--PRPADRRDAPADCAYLWRILTPRRGRA 70
            +RS  PP   R      PP T R SR RT P   R +  R +P         +T RR R+
Sbjct: 1946 SRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSP---------VTRRRSRS 1996

Query: 71   RRSDVGARHRACGRRDVLLSRQGPANPEGARRVVGGQERVWPAVRRGRGGSMFRLLSWSL 130
            R S V  R        V   R     P   RR    +  + P  +R R  S   +   S 
Sbjct: 1997 RTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPR-KRSRSRSPLAIRRRSR 2055

Query: 131  GRGFLRAAGRRCRGCS-----ARLLPGLAGGPGPEVQVPPSRVAPHGRGPGLLPLLAALA 185
             R    A G+R    S      R   G +         P +R     R P +    + ++
Sbjct: 2056 SRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMS 2115

Query: 186  WFSRPA 191
             FSRP+
Sbjct: 2116 CFSRPS 2121



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 40/118 (33%), Positives = 50/118 (42%), Gaps = 16/118 (13%)

Query: 11   YFARSPAPPPPSRS------GAPPQPPATLRPSRRRTRP-PRPADRRDAPADCAYLWRIL 63
            Y +RSPA    SR+      G    PP + + SR RT P P    R  A        R  
Sbjct: 1820 YHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSR 1879

Query: 64   TP----RRGRARRSDVGARHRACGRRDVLLSR-QGPANPEGARRVVGGQERVWPAVRR 116
            TP    RR R+R S V +R R+  R  V   R +  A+P   RR    + R  P  RR
Sbjct: 1880 TPLISRRRSRSRTSPV-SRRRSRSRTSVTRRRSRSRASPVSRRR---SRSRTPPVTRR 1933



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 50/177 (28%), Positives = 62/177 (35%), Gaps = 23/177 (12%)

Query: 7   TSVPYFARSPAPPPPSRSG-APPQPPATLRPSRRRTRPPRPADRRDAPADCAYLWRILTP 65
           T  P   RS +  P  RSG +  + PA    SR RT   R   R   PA  +   R  TP
Sbjct: 627 TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTP 686

Query: 66  RRGRARRSDVGARHRACGRRDVLLSRQGPANPEGARRVVGGQER---VWPAVRRGRGGSM 122
            R    RS    R R+  R  V   R     P+   R     ER      + RR R  S 
Sbjct: 687 ARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSS 746

Query: 123 FRLLSWSLGRGFLRAAGRRCRGCSA------------RLLPGLAGGPGPEVQVPPSR 167
             +          R + RR R  S+            R L G +  P  + Q PP R
Sbjct: 747 PEMKK-------SRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRR 796



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 45/141 (31%), Positives = 53/141 (37%), Gaps = 22/141 (15%)

Query: 23  RSGAPPQPPATLRPSRRRTRPPRPADRRDAPADCAYLWRILTPRRGRAR--------RSD 74
           R  +  + PAT   SR RT   R   R   PA      R  T RR R+R        RS 
Sbjct: 559 RGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR 618

Query: 75  VGARHRACGRRDVLLSRQGPANPEGARRVVGGQERVWPAVRRG---------RGGSMFRL 125
             AR R+  R  V   R+   +   ARR   G+ R     RRG         RG S  R 
Sbjct: 619 TPARRRSRTRSPV---RRRSRSRSPARR--SGRSRSRTPARRGRSRSRTPARRGRSRSRT 673

Query: 126 LSWSLGRGFLRAAGRRCRGCS 146
            +   GR   R   RR R  S
Sbjct: 674 PARRSGRSRSRTPARRGRSRS 694



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 38/111 (34%), Positives = 44/111 (39%), Gaps = 20/111 (18%)

Query: 15   SPAPPPPSRSGAPPQPPATLRPSRRRT-----RPPR----PADRRDAPADCAYLWRILTP 65
            SPAP   SRS A P   AT R SR RT     R  R    P  RR + +  +     +T 
Sbjct: 1857 SPAPWKRSRSRASP---ATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTS-----VTR 1908

Query: 66   RRGRARRSDVGARHRACGRRDVLLSRQGPANPEGARRVVGGQERVWPAVRR 116
            RR R+R S V  R        V   R     P   RR    + R  P  RR
Sbjct: 1909 RRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRR---SRSRTPPVTRR 1956



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 16/90 (17%)

Query: 14   RSPAPPPPSRSGAPPQPPATLRPSRRRTR-PPRPADRRDAPADCAYLWRILTPRRGRARR 72
            R P+P   S + + P+ P   R +RR +R  P P  +   P           PRR  +R 
Sbjct: 1645 RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTP-----------PRRRSSRS 1693

Query: 73   SDVGARHRACGRRDVLLSRQGPANPEGARR 102
            S    R     RR    SR   ++PE   R
Sbjct: 1694 SPELTRKARLSRR----SRSASSSPETRSR 1719


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 20/49 (40%), Positives = 23/49 (46%), Gaps = 3/49 (6%)

Query: 4   PHTTSVPYFARSPAPP---PPSRSGAPPQPPATLRPSRRRTRPPRPADR 49
           P + S    +  P PP   PPSR  APP PP  +R   R   PP P  R
Sbjct: 299 PTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYR 347



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 9/58 (15%)

Query: 1   MAQPHTTS---VPYFARSPAPPPPSRSGAPPQPPATLRPS------RRRTRPPRPADR 49
           +++P+TTS   + + + +P PPPP R    P  P  +  S      R +  PP P  R
Sbjct: 159 LSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQR 216



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 23/76 (30%), Positives = 30/76 (39%), Gaps = 16/76 (21%)

Query: 13  ARSPAPPPPSRS--GAPPQPPATLRPSRRRTRPP--------------RPADRRDAPADC 56
           +R   PPPPSR+  G PP PP  LR   R +                  P +   AP + 
Sbjct: 355 SRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEY 414

Query: 57  AYLWRILTPRRGRARR 72
            +  RI   +  RA R
Sbjct: 415 KHFQRIYPSKTNRAAR 430



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 19/56 (33%), Positives = 23/56 (41%), Gaps = 7/56 (12%)

Query: 4   PHTTSVPYFARSPAPPPP-----SRSGAPPQPPATLRPSR--RRTRPPRPADRRDA 52
           P     P    +P PPPP     +R   PP PP  +  S    R +PP P  R  A
Sbjct: 313 PPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPA 368



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 3/36 (8%)

Query: 19  PPPSRSGAPPQPPATLRPSRRRTRPPRPADRRDAPA 54
           P P R  APP PP +  PS    RPP PA  RD P+
Sbjct: 288 PGPVRGLAPP-PPTSASPSLLSNRPPPPA--RDPPS 320



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 11/50 (22%)

Query: 14  RSPAPPPPSRSGAP------PQPPATLRPSRRRTRPPRPA----DRRDAP 53
           R  APPPP+ S +P      P PPA   PSR    PP P       RDAP
Sbjct: 292 RGLAPPPPT-SASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAP 340


>gi|169171690 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 157

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 29/88 (32%), Positives = 34/88 (38%), Gaps = 8/88 (9%)

Query: 14  RSPAPPPPSRSGAPPQPPATLRPSRRRTRPPRPADRRDAPADCAYLWRILTPRRGRARRS 73
           R   PP P R   P QPP+  R  R     P    R DA A C     +  PR    RR+
Sbjct: 71  RRTVPPCPRRPARPSQPPSAARRERALLANPPQRPRGDAGALC-----VSRPRGACPRRA 125

Query: 74  DVGARHRACGRRDVLLSRQGPANPEGAR 101
             GA  R  G       ++ P  P  AR
Sbjct: 126 PAGAPWRLGGE---FRKQRPPQQPRDAR 150



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 36/102 (35%), Positives = 39/102 (38%), Gaps = 19/102 (18%)

Query: 16  PAPPPPSRSGAPPQPPATLRPSRRRTRPP---RPADRRDAPADCAYLWRILTPRRGRARR 72
           P  PPP          AT R   RRT PP   RPA R   P   A   R L     +  R
Sbjct: 48  PRAPPPGPRPTAAATRATFRVPERRTVPPCPRRPA-RPSQPPSAARRERALLANPPQRPR 106

Query: 73  SDVGA----RHR-ACGRRDVLLSRQGPANPEGARRVVGGQER 109
            D GA    R R AC RR           P GA   +GG+ R
Sbjct: 107 GDAGALCVSRPRGACPRR----------APAGAPWRLGGEFR 138


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,959,612
Number of Sequences: 37866
Number of extensions: 1171644
Number of successful extensions: 15555
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 412
Number of HSP's that attempted gapping in prelim test: 12317
Number of HSP's gapped (non-prelim): 2927
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.