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Search of human proteins with 22538461
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
(2440 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 4871 0.0
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 1498 0.0
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 1472 0.0
gi|169212142 PREDICTED: similar to NCOR [Homo sapiens] 118 6e-26
gi|209977080 REST corepressor 3 isoform a [Homo sapiens] 99 5e-20
gi|8922733 REST corepressor 3 isoform d [Homo sapiens] 99 5e-20
gi|7661892 REST corepressor 1 [Homo sapiens] 96 6e-19
gi|209977084 REST corepressor 3 isoform c [Homo sapiens] 93 3e-18
gi|27734799 REST corepressor 2 [Homo sapiens] 86 6e-16
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 80 2e-14
gi|91982772 mucin 17 [Homo sapiens] 75 1e-12
gi|148746195 trichohyalin [Homo sapiens] 70 3e-11
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 68 1e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 68 1e-10
gi|104526627 triadin [Homo sapiens] 68 1e-10
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 67 2e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 67 2e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 67 3e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 65 1e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 64 2e-09
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 63 3e-09
gi|210032580 SET domain containing 1B [Homo sapiens] 63 3e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 62 5e-09
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 61 1e-08
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 61 1e-08
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 61 1e-08
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 61 1e-08
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 60 3e-08
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 60 3e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 60 3e-08
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 4871 bits (12634), Expect = 0.0
Identities = 2440/2440 (100%), Positives = 2440/2440 (100%)
Query: 1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ 60
MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
Sbjct: 1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ 60
Query: 61 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ 120
QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
Sbjct: 61 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ 120
Query: 121 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE 180
RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
Sbjct: 121 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE 180
Query: 181 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY 240
LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
Sbjct: 181 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY 240
Query: 241 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHAR 300
DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHAR
Sbjct: 241 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHAR 300
Query: 301 KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQ 360
KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQ
Sbjct: 301 KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQ 360
Query: 361 RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM 420
RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM
Sbjct: 361 RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM 420
Query: 421 NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYL 480
NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYL
Sbjct: 421 NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYL 480
Query: 481 TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDE 540
TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDE
Sbjct: 481 TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDE 540
Query: 541 KEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAA 600
KEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAA
Sbjct: 541 KEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAA 600
Query: 601 AAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEA 660
AAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEA
Sbjct: 601 AAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEA 660
Query: 661 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE 720
QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE
Sbjct: 661 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE 720
Query: 721 ENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESV 780
ENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESV
Sbjct: 721 ENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESV 780
Query: 781 ETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDN 840
ETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDN
Sbjct: 781 ETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDN 840
Query: 841 TKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPERQRMFP 900
TKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPERQRMFP
Sbjct: 841 TKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPERQRMFP 900
Query: 901 MDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALY 960
MDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALY
Sbjct: 901 MDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALY 960
Query: 961 QRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWEVLQPAPHQVITNLPE 1020
QRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWEVLQPAPHQVITNLPE
Sbjct: 961 QRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWEVLQPAPHQVITNLPE 1020
Query: 1021 GVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQETPK 1080
GVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQETPK
Sbjct: 1021 GVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQETPK 1080
Query: 1081 PSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAIQ 1140
PSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAIQ
Sbjct: 1081 PSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAIQ 1140
Query: 1141 EGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVKGSISRMPIEDSSPEKG 1200
EGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVKGSISRMPIEDSSPEKG
Sbjct: 1141 EGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVKGSISRMPIEDSSPEKG 1200
Query: 1201 REEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLKRSYESVEGNIKQGMSM 1260
REEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLKRSYESVEGNIKQGMSM
Sbjct: 1201 REEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLKRSYESVEGNIKQGMSM 1260
Query: 1261 RESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYPKQIKR 1320
RESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYPKQIKR
Sbjct: 1261 RESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYPKQIKR 1320
Query: 1321 ESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPIIEG 1380
ESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPIIEG
Sbjct: 1321 ESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPIIEG 1380
Query: 1381 SISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYEDVKA 1440
SISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYEDVKA
Sbjct: 1381 SISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYEDVKA 1440
Query: 1441 GETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRTPVSYQNTMSRGSPMMN 1500
GETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRTPVSYQNTMSRGSPMMN
Sbjct: 1441 GETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRTPVSYQNTMSRGSPMMN 1500
Query: 1501 RTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVY 1560
RTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVY
Sbjct: 1501 RTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVY 1560
Query: 1561 RSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITS 1620
RSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITS
Sbjct: 1561 RSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITS 1620
Query: 1621 QQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILVPHPGGTSTPPMDRITY 1680
QQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILVPHPGGTSTPPMDRITY
Sbjct: 1621 QQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILVPHPGGTSTPPMDRITY 1680
Query: 1681 IPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKERERERIAAASSDLYLRP 1740
IPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKERERERIAAASSDLYLRP
Sbjct: 1681 IPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKERERERIAAASSDLYLRP 1740
Query: 1741 GSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPA 1800
GSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPA
Sbjct: 1741 GSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPA 1800
Query: 1801 GGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKESKHEAARLEENLRSRSAAV 1860
GGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKESKHEAARLEENLRSRSAAV
Sbjct: 1801 GGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKESKHEAARLEENLRSRSAAV 1860
Query: 1861 SEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYEEELR 1920
SEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYEEELR
Sbjct: 1861 SEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYEEELR 1920
Query: 1921 TRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDAIEVISPAS 1980
TRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDAIEVISPAS
Sbjct: 1921 TRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDAIEVISPAS 1980
Query: 1981 SPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMG 2040
SPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMG
Sbjct: 1981 SPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMG 2040
Query: 2041 QVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNR 2100
QVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNR
Sbjct: 2041 QVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNR 2100
Query: 2101 YSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSSEPYEPISPPQVPVVHE 2160
YSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSSEPYEPISPPQVPVVHE
Sbjct: 2101 YSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSSEPYEPISPPQVPVVHE 2160
Query: 2161 KQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSG 2220
KQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSG
Sbjct: 2161 KQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSG 2220
Query: 2221 GGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVE 2280
GGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVE
Sbjct: 2221 GGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVE 2280
Query: 2281 DHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIP 2340
DHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIP
Sbjct: 2281 DHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIP 2340
Query: 2341 GQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTP 2400
GQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTP
Sbjct: 2341 GQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTP 2400
Query: 2401 IACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD 2440
IACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
Sbjct: 2401 IACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD 2440
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 1498 bits (3877), Expect = 0.0
Identities = 1086/2660 (40%), Positives = 1442/2660 (54%), Gaps = 357/2660 (13%)
Query: 1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ 60
MS S P Q +TE RYPPHS+ Y R + + +Y+ H AS L
Sbjct: 1 MSGSTQPVAQTWRATEP-RYPPHSLSYPVQIARTHTDVGLLEYQ--HHSRDYASHLSPGS 57
Query: 61 QQQQLRRRPSLLSEFHPGSDRPQER--RTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSH 118
Q RRRPSLLSEF PG++R QE R + P + + +ESKRPRLE + D
Sbjct: 58 IIQPQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPD-- 115
Query: 119 FQRVSAAVLPLVHPLP---EGLRA-SADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPS 174
PL+ P P G A S D KD + GK E P SP S + P
Sbjct: 116 ---------PLLRPSPLLATGQPAGSEDLTKDRSLTGKLE-PVSPPSPPHTDPELELVPP 165
Query: 175 KLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRS 234
+LSKEELIQ+MDRVDREI VEQQI KLKKKQQQLEEEAAKPPEPEKPVSPPP+E KHRS
Sbjct: 166 RLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRS 225
Query: 235 IVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFK 294
+VQIIYDENRKKAE AH+I EGLGP+VELPLYNQPSDT+ YHENIK NQ MRKKLIL+FK
Sbjct: 226 LVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFK 285
Query: 295 RRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQRE 354
RRNHARKQ EQK CQRYDQLMEAWEKKV+RIENNPRR+AKESK REYYEKQFPEIRKQRE
Sbjct: 286 RRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRE 345
Query: 355 QQERFQ-RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQR 413
QER Q RVGQRG+GLS + ARSEHE+SEIIDGLSEQEN EKQMRQL+VIPPM++DA+Q+
Sbjct: 346 LQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQ 405
Query: 414 RVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPD 473
R+KFINMNGLM DPMKVYKDRQ MN+W++ EKE F++KF+QHPKNFGLIAS+LERK+V +
Sbjct: 406 RIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAE 465
Query: 474 CVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEE--DKAEKTEKKEEE 531
CVLYYYLTKKNENYK+LVRR+Y +RRG++QQ + Q+++ +++++ ++ + EK E+E
Sbjct: 466 CVLYYYLTKKNENYKSLVRRSY-RRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKE 524
Query: 532 KKDEEEKDEKEDSKENTKE---KDKIDGTA-EETEEREQATPRGRKTANSQGRRKGRITR 587
K+ E EK+E++ EN KE K+K D T+ E+ +E+E +GRKTANSQGRRKGRITR
Sbjct: 525 KEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITR 584
Query: 588 SMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNW 647
SM NEA + A + E S E E+SRWTEEEME AKKGL+EHGRNW
Sbjct: 585 SMANEANSEEAITPQQS----------AELASMELNESSRWTEEEMETAKKGLLEHGRNW 634
Query: 648 AAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVS 707
+AIA+MVG+K+ +QCKNFYFNYK+R NLD +LQQHK K ++ R + + AS +
Sbjct: 635 SAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEA 694
Query: 708 A----QEDEDIEAS----NEEENPEDSEV------EAVKPSEDSPENATSRGNTE--PAV 751
A EDE++EAS NEEE E++E E + P + +TE P+
Sbjct: 695 AFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSP 754
Query: 752 ELEPTTET---APSTSPSLAV------PSTKPAEDESVETQ---VNDSISAET------- 792
E +T P +L P T P ED T+ +++ A T
Sbjct: 755 HTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPS 814
Query: 793 -AEQMDVDQQEHSAEEGSVCDP--------PPATKADSVD---VEVRVPENHASKVEGDN 840
+ V +E EE + P PPA + +VD E V + E
Sbjct: 815 PSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGP 874
Query: 841 TKERDLDRASEKVE----PRDEDLVVAQQINAQRPEPQSDNDSSATCSADE--DVDGEPE 894
K +D + A E ++ + A+ D+DSSATCSADE + +G +
Sbjct: 875 AKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDK 934
Query: 895 RQRMFPMDSKPSLLNPTGSILV-SSPLKPNPLDLPQLQHRAAVIPPMVS---------CT 944
+ + P +PSLL PTG +SP K PLDL QL+ RAA IPP+V+
Sbjct: 935 NRLLSP---RPSLLTPTGDPRANASPQK--PLDLKQLKQRAAAIPPIVTKVHEPPREDAA 989
Query: 945 PCN-IPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRS-------------- 989
P P P + S+ + R D E
Sbjct: 990 PTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKL 1049
Query: 990 -STSPCGTS--KSPNREWEVLQPAPH----QVITNLPEGVRLP-----TTRPTRPPPPLI 1037
PC TS P EV++ +PH + P G LP T RP P PP I
Sbjct: 1050 PGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTI 1109
Query: 1038 PSSKTTVASEKPSFIMG---GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQ 1094
+ ++S K ++ G+ISQG ++ Y++ P VG +++GLP
Sbjct: 1110 SNPPPLISSAKHPSVLERQIGAISQG-----MSVQLHVPYSEHAKAP-VGPVTMGLPLPM 1163
Query: 1095 ESAKSATLPYIKQEEFSPRSQNSQPEGLLV-RAQHEGVVRGTA-GAIQEGSITRGTPTSK 1152
+ K A +KQE+ SPR Q PE L V AQ V+RGTA G++ GSIT+G P+++
Sbjct: 1164 DPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTR 1223
Query: 1153 ISVESIPSLRGSITQGTPALPQTGIPTEALVKGSISRMPIEDSSP--EKGREEAASKGHV 1210
+ +S + RGSIT GTPA + L KG+I+R+ EDS ++GRE++ KGHV
Sbjct: 1224 VPSDSAITYRGSITHGTPA--------DVLYKGTITRIIGEDSPSRLDRGREDSLPKGHV 1275
Query: 1211 IYEGKSGHILSYDNIKNA-----REGTRSPRTAHEISL-KRSYESVEGNIKQGMSMRESP 1264
IYEGK GH+LSY+ + +G S HE + KR+Y+ +EG + + +S
Sbjct: 1276 IYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAIS----- 1330
Query: 1265 VSAPLEGLICRALP--RGSPHSDLKERTVLSGSIMQGTPRATTESFEDGL-KYPKQIKRE 1321
SA +EGL+ RA+P R SPH LKE+ + GSI QG PR+ E+ ED L + K +KRE
Sbjct: 1331 -SASIEGLMGRAIPPERHSPH-HLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKRE 1388
Query: 1322 S-----PPIRAFEGAI-------TKGKP-YDG-ITTIKEMGRSIHEIPRQDILTQESRKT 1367
PP R A K KP ++G + T+KE GRSIHEIPR+++ R T
Sbjct: 1389 GTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREEL-----RHT 1443
Query: 1368 PEVVQSTRPIIEGSISQGTPIKFDNN-SGQSAIKHNVKSLITGPSKLSRGMPPLEIVPEN 1426
PE+ + RP+ EGSI+QGTP+K+D S + KH+V+SLI P + + PL+++ +
Sbjct: 1444 PELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMAD- 1502
Query: 1427 IKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRST---LHEAPKAQLSPGIYDDTSARR 1483
+ +ER YE E+++SR + SSG S+ R + E K + SP Y+D A
Sbjct: 1503 ARALERACYE-----ESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGA-- 1555
Query: 1484 TPVSYQNTMSRGSPMMN-----RTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGV 1538
+ + RGSP+ R + ++SS+K+ + +RK T TP + AKSP V
Sbjct: 1556 ---PFAGHLPRGSPVTTREPTPRLQEGSLSSSKA-SQDRKLTSTPRE----IAKSPHSTV 1607
Query: 1539 DPVVSH--SPFDPHHRGSTAGEVYRSHLPTHLDP-AMPFHRALDPAAAAYLFQRQLSPTP 1595
H SP++ RG + ++YRSH+P DP ++P LD AAAAY R L+P P
Sbjct: 1608 PEHHPHPISPYEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLD-AAAAYYLPRHLAPNP 1666
Query: 1596 GYPSQYQLY---------AMENTRQTILNDYITSQQMQVNL------RPDVARGLSPREQ 1640
YP Y Y A+EN RQTI+NDYITSQQM N R D+ RGLSPRE
Sbjct: 1667 TYPHLYPPYLIRGYPDTAALEN-RQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRES 1725
Query: 1641 PLGLPYPA-TRGIIDLTNMPP-TILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASM 1698
L L Y A RGIIDL+ +P +LVP GT MDR+ Y+P F R ++S+ +
Sbjct: 1726 SLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSR-HSSSPL 1784
Query: 1699 SPGHPTHL---AAAASAEREREREREKERERER---IAAASSDL----YLRPGSEQ---- 1744
SPG PTHL +S+ERER+R+RE++R+RER I +++ + RPG+EQ
Sbjct: 1785 SPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGS 1844
Query: 1745 ----------PGRPGSHGYVRSPSP-SVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQL 1793
RP SH + SP S RTQ+ LQQRPSV T +IT ++P+
Sbjct: 1845 SGSSGGGGGSSSRPASHSHAHQHSPISPRTQDA-LQQRPSVLHNTGMKGIITAVEPSTPT 1903
Query: 1794 RIMPLPAGGPSISQGLPASRYNTAADA-LAALVDAAASAPQMDVSKTKESKHEAARLEEN 1852
+ P PA+ + A L +D V KE+
Sbjct: 1904 VLRSTSTSSPV----RPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPR-------- 1951
Query: 1853 LRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPK 1912
A E+ + + + K + ++ PS +P V PP
Sbjct: 1952 -----VARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLV-----------PPV 1995
Query: 1913 SRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSS------SSLSSHRY 1966
S + RT K A + AS D +QS S SL H
Sbjct: 1996 SGHATIARTPAKN--LAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGS 2053
Query: 1967 ETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGP---------LHHY 2017
+ +E +SP SSP+ +K E + + E + + GP L H
Sbjct: 2054 SYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHL 2113
Query: 2018 RP---QQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSS-QTP 2073
RP Q S SP Q P V R++TLA HI ++ITQD+ R+ P
Sbjct: 2114 RPLPESQPSSSPLLQTAPG--------VKGHQRVVTLAQHISEVITQDYTRHHPQQLSAP 2165
Query: 2074 QQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRP 2133
P +F + ++ +R S+ Y P H P +R SP S G +
Sbjct: 2166 LPAPLYSFPGASCPVLD--LRRPPSDLYLPPPD-----HGAP-ARGSPH-----SEGGKR 2212
Query: 2134 GKSPERSHV---SSEPYEPISPPQ--VPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSI 2188
P ++ V + EP+SPP+ H + LL + G + R ++SPG+
Sbjct: 2213 SPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNT 2272
Query: 2189 SYLPSFFTKL-ENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSV 2247
S P+FF+KL E+ S MVKSKKQEI +KLN+ + + +QPGTEIFN+PA+T +G +
Sbjct: 2273 SQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLM 2332
Query: 2248 SSRGHSFADPAS-NLGLEDIIRKALMGSFDDKVEDHGVVMS--QPMGVVPGTANTSVVTS 2304
+ R + + AS N+GLE IIRKALMG +D E + + P+ +T+
Sbjct: 2333 TYRSQAVQEHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITA 2392
Query: 2305 GETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHR 2364
+ R + SP GG K K+ + +SRK+KSP P G +RP SVSSVHSEGD +R
Sbjct: 2393 ADGRSDHTLTSPGGGG--KAKVSGRPSSRKAKSPAP--GLASGDRPPSVSSVHSEGDCNR 2448
Query: 2365 QTP--GWAWEDRPSSTGSTQFPYNPLTMRM---LSSTPPTPIACAPSAVNQAAPHQQNRI 2419
+TP WEDRPSS GST FPYNPL MR+ + ++PP P A S A PH
Sbjct: 2449 RTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSG-PLAGPH---HA 2504
Query: 2420 WEREPAPLLSAQYETLSDSD 2439
W+ EP PLL +QYETLSDS+
Sbjct: 2505 WDEEPKPLLCSQYETLSDSE 2524
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 1472 bits (3812), Expect = 0.0
Identities = 1080/2648 (40%), Positives = 1422/2648 (53%), Gaps = 395/2648 (14%)
Query: 1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ 60
MS S P Q +TE RYPPHS+ Y R + + +Y+ H AS L
Sbjct: 1 MSGSTQPVAQTWRATEP-RYPPHSLSYPVQIARTHTDVGLLEYQ--HHSRDYASHLSPGS 57
Query: 61 QQQQLRRRPSLLSEFHPGSDRPQER--RTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSH 118
Q RRRPSLLSEF PG++R QE R + P + + +ESKRPRLE + D
Sbjct: 58 IIQPQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPD-- 115
Query: 119 FQRVSAAVLPLVHPLP---EGLRA-SADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPS 174
PL+ P P G A S D KD + GK E P SP S + P
Sbjct: 116 ---------PLLRPSPLLATGQPAGSEDLTKDRSLTGKLE-PVSPPSPPHTDPELELVPP 165
Query: 175 KLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRS 234
+LSKEELIQ+MDRVDREI VEQQI KLKKKQQQLEEEAAKPPEPEKPVSPPP+E KHRS
Sbjct: 166 RLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRS 225
Query: 235 IVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFK 294
+VQIIYDENRKKAE AH+I EGLGP+VELPLYNQPSDT+ YHENIK NQ MRKKLIL+FK
Sbjct: 226 LVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFK 285
Query: 295 RRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQRE 354
RRNHARKQ EQK CQRYDQLMEAWEKKV+RIENNPRR+AKESK REYYEKQFPEIRKQRE
Sbjct: 286 RRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRE 345
Query: 355 QQERFQ-RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQR 413
QER Q RVGQRG+GLS + ARSEHE+SEIIDGLSEQEN EKQMRQL+VIPPM++DA+Q+
Sbjct: 346 LQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQ 405
Query: 414 RVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPD 473
R+KFINMNGLM DPMKVYKDRQ MN+W++ EKE F++KF+QHPKNFGLIAS+LERK+V +
Sbjct: 406 RIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAE 465
Query: 474 CVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEE--DKAEKTEKKEEE 531
CVLYYYLTKKNENYK+LVRR+Y +RRG++QQ + Q+++ +++++ ++ + EK E+E
Sbjct: 466 CVLYYYLTKKNENYKSLVRRSY-RRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKE 524
Query: 532 KKDEEEKDEKEDSKENTKE---KDKIDGTA-EETEEREQATPRGRKTANSQGRRKGRITR 587
K+ E EK+E++ EN KE K+K D T+ E+ +E+E +GRKTANSQGRRKGRITR
Sbjct: 525 KEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITR 584
Query: 588 SMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNW 647
SM NEA + A + E S E E+SRWTEEEME AKKGL+EHGRNW
Sbjct: 585 SMANEANSEEAITPQQS----------AELASMELNESSRWTEEEMETAKKGLLEHGRNW 634
Query: 648 AAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVS 707
+AIA+MVG+K+ +QCKNFYFNYK+R NLD +LQQHK K ++ R + + AS +
Sbjct: 635 SAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEA 694
Query: 708 A----QEDEDIEAS----NEEENPEDSEVEAVKPSE----DSP--ENATSRGNTEPAVEL 753
A EDE++EAS NEEE E++E S+ SP E A G P
Sbjct: 695 AFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPK--- 751
Query: 754 EPTTETAPSTSPSLAVPSTKPAEDESVETQ---VNDSISAET--------AEQMDVDQQE 802
P T A P P T P ED T+ +++ A T + V +E
Sbjct: 752 PPATLGADGPPPG---PPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKE 808
Query: 803 HSAEEGSVCDP--------PPATKADSVD---VEVRVPENHASKVEGDNTKERDLDRASE 851
EE + P PPA + +VD E V + E K +D + A
Sbjct: 809 EKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEA 868
Query: 852 KVE----PRDEDLVVAQQINAQRPEPQSDNDSSATCSADE--DVDGEPERQRMFPMDSKP 905
E ++ + A+ D+DSSATCSADE + +G + + + P +P
Sbjct: 869 TAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSP---RP 925
Query: 906 SLLNPTGSILV-SSPLKPNPLDLPQLQHRAAVIPPM----------VSCTPCN-IPIGTP 953
SLL PTG +SP K PLDL QL+ RAA IPP+ P P P
Sbjct: 926 SLLTPTGDPRANASPQK--PLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPP 983
Query: 954 VSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRS---------------STSPCGTS- 997
+ S+ + R D E PC TS
Sbjct: 984 PPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSG 1043
Query: 998 -KSPNREWEVLQPAPH----QVITNLPEGVRLP-----TTRPTRPPPPLIPSSKTTVASE 1047
P EV++ +PH + P G LP T RP P PP I + ++S
Sbjct: 1044 LPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSA 1103
Query: 1048 KPSFIMG---GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPY 1104
K ++ G+ISQG ++ Y++ P VG +++GLP + K A
Sbjct: 1104 KHPSVLERQIGAISQG-----MSVQLHVPYSEHAKAP-VGPVTMGLPLPMDPKKLAPFSG 1157
Query: 1105 IKQEEFSPRSQNSQPEGLLV-RAQHEGVVRGTA-GAIQEGSITRGTPTSKISVESIPSLR 1162
+KQE+ SPR Q PE L V AQ V+RGTA G++ GSIT+G P++++ +S + R
Sbjct: 1158 VKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTRVPSDSAITYR 1217
Query: 1163 GSITQGTPALPQTGIPTEALVKGSISRMPIEDSSP--EKGREEAASKGHVIYEGKSGHIL 1220
GSIT GTPA + L KG+I+R+ EDS ++GRE++ KGHVIYEGK GH+L
Sbjct: 1218 GSITHGTPA--------DVLYKGTITRIIGEDSPSRLDRGREDSLPKGHVIYEGKKGHVL 1269
Query: 1221 SYDNIKNA-----REGTRSPRTAHEISL-KRSYESVEGNIKQGMSMRESPVSAPLEGLIC 1274
SY+ + +G S HE + KR+Y+ +EG + + +S SA +EGL+
Sbjct: 1270 SYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAIS------SASIEGLMG 1323
Query: 1275 RALP--RGSPHSDLKERTVLSGSIMQGTPRATTESFEDGL-KYPKQIKRES-----PPIR 1326
RA+P R SPH LKE+ + GSI QG PR+ E+ ED L + K +KRE PP R
Sbjct: 1324 RAIPPERHSPH-HLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREGTPPPPPPSR 1382
Query: 1327 AFEGAI-------TKGKP-YDG-ITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPI 1377
A K KP ++G + T+KE GRSIHEIPR+++ R TPE+ + RP+
Sbjct: 1383 DLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREEL-----RHTPELPLAPRPL 1437
Query: 1378 IEGSISQGTPIKFDNN-SGQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYE 1436
EGSI+QGTP+K+D S + KH+V+SLI P + + PL+++ + + +ER YE
Sbjct: 1438 KEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMAD-ARALERACYE 1496
Query: 1437 DVKAGETVRSRHTSVVSSGPSVLRST---LHEAPKAQLSPGIYDDTSARRTPVSYQNTMS 1493
E+++SR + SSG S+ R + E K + SP Y+D A + +
Sbjct: 1497 -----ESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGA-----PFAGHLP 1546
Query: 1494 RGSPMMN-----RTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSH--SP 1546
RGSP+ R + ++SS+K+ + +RK T TP + AKSP V H SP
Sbjct: 1547 RGSPVTTREPTPRLQEGSLSSSKA-SQDRKLTSTPRE----IAKSPHSTVPEHHPHPISP 1601
Query: 1547 FDPHHRGSTAGEVYRSHLPTHLDP-AMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLY- 1604
++ RG + ++YRSH+P DP ++P LD AAAAY R L+P P YP Y Y
Sbjct: 1602 YEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLD-AAAAYYLPRHLAPNPTYPHLYPPYL 1660
Query: 1605 --------AMENTRQTILNDYITSQQMQVNL------RPDVARGLSPREQPLGLPYPA-T 1649
A+EN RQTI+NDYITSQQM N R D+ RGLSPRE L L Y A
Sbjct: 1661 IRGYPDTAALEN-RQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGP 1719
Query: 1650 RGIIDLTNMPP-TILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHL-- 1706
RGIIDL+ +P +LVP GT MDR+ Y+P F R ++S+ +SPG PTHL
Sbjct: 1720 RGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSR-HSSSPLSPGGPTHLTK 1778
Query: 1707 -AAAASAEREREREREKERERER---IAAASSDL----YLRPGSEQ-------------- 1744
+S+ERER+R+RE++R+RER I +++ + RPG+EQ
Sbjct: 1779 PTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGS 1838
Query: 1745 PGRPGSHGYVRSPSP-SVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPAGGP 1803
RP SH + SP S RTQ+ LQQRPSV T +IT ++P+ + P
Sbjct: 1839 SSRPASHSHAHQHSPISPRTQDA-LQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSP 1897
Query: 1804 SISQGLPASRYNTAADA-LAALVDAAASAPQMDVSKTKESKHEAARLEENLRSRSAAVSE 1862
PA+ + A L +D V KE+ A E
Sbjct: 1898 V----RPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPR-------------VARPE 1940
Query: 1863 QQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYEEELRTR 1922
+ + + + K + ++ PS +P V PP S + RT
Sbjct: 1941 RPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLV-----------PPVSGHATIARTP 1989
Query: 1923 GKTTITAANFIDVIITRQIASDKDARERGSQSSDSS------SSLSSHRYETPSDAIEVI 1976
K A + AS D +QS S SL H + +E +
Sbjct: 1990 AKN--LAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPV 2047
Query: 1977 SPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGP---------LHHYRP---QQESP 2024
SP SSP+ +K E + + E + + GP L H RP Q S
Sbjct: 2048 SPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSS 2107
Query: 2025 SPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSS-QTPQQPPTSTFQN 2083
SP Q P V R++TLA HI ++ITQD+ R+ P P +F
Sbjct: 2108 SPLLQTAPG--------VKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPG 2159
Query: 2084 SPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHV- 2142
+ ++ +R S+ Y P H P +R SP S G + P ++ V
Sbjct: 2160 ASCPVLD--LRRPPSDLYLPPPD-----HGAP-ARGSPH-----SEGGKRSPEPNKTSVL 2206
Query: 2143 --SSEPYEPISPPQ--VPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKL 2198
+ EP+SPP+ H + LL + G + R ++SPG+ S P+FF+KL
Sbjct: 2207 GGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFFSKL 2266
Query: 2199 -ENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADP 2257
E+ S MVKSKKQEI +KLN+ + + +QPGTEIFN+PA+T +G ++ R + +
Sbjct: 2267 TESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQEH 2326
Query: 2258 AS-NLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSP 2316
AS N+GLE IIRKALMG
Sbjct: 2327 ASTNMGLEAIIRKALMG------------------------------------------- 2343
Query: 2317 HSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTP--GWAWEDR 2374
GG K K+ + +SRK+KSP P G +RP SVSSVHSEGD +R+TP WEDR
Sbjct: 2344 -GGG--KAKVSGRPSSRKAKSPAP--GLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDR 2398
Query: 2375 PSSTGSTQFPYNPLTMRM---LSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQ 2431
PSS GST FPYNPL MR+ + ++PP P A S A PH W+ EP PLL +Q
Sbjct: 2399 PSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSG-PLAGPH---HAWDEEPKPLLCSQ 2454
Query: 2432 YETLSDSD 2439
YETLSDS+
Sbjct: 2455 YETLSDSE 2462
>gi|169212142 PREDICTED: similar to NCOR [Homo sapiens]
Length = 123
Score = 118 bits (296), Expect = 6e-26
Identities = 57/63 (90%), Positives = 61/63 (96%)
Query: 144 KKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLK 203
++DP FGGKHEAPSSPIS QPCGDDQNASPSKLSKEELIQSMDR++REIAKVEQQILKLK
Sbjct: 35 QQDPTFGGKHEAPSSPISRQPCGDDQNASPSKLSKEELIQSMDRINREIAKVEQQILKLK 94
Query: 204 KKQ 206
KKQ
Sbjct: 95 KKQ 97
Score = 80.5 bits (197), Expect = 2e-14
Identities = 42/74 (56%), Positives = 51/74 (68%), Gaps = 5/74 (6%)
Query: 1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ 60
MSSSGYPPNQGAFSTEQSRYPPHSV+YTFP+TRHQQ+ P + H + +S + +Q
Sbjct: 1 MSSSGYPPNQGAFSTEQSRYPPHSVKYTFPSTRHQQD---PTFGGKH--EAPSSPISRQP 55
Query: 61 QQQQLRRRPSLLSE 74
PS LS+
Sbjct: 56 CGDDQNASPSKLSK 69
>gi|209977080 REST corepressor 3 isoform a [Homo sapiens]
Length = 553
Score = 99.0 bits (245), Expect = 5e-20
Identities = 81/345 (23%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 436 FMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNY 495
F + WT +K +F+ F H K+F I L K++ V YYY KK + +L+ R
Sbjct: 143 FPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQA 202
Query: 496 GKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEK-------------- 541
K R+ Q E+ + + ++ KKE +K+ E+ +
Sbjct: 203 RKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSL 262
Query: 542 EDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAA 601
+ + + K + T+E A AN+ R+ S+ + A +
Sbjct: 263 QHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNS 322
Query: 602 AATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQ 661
A ++ + P S + + +RWT EE +A +G+ ++G+++ AIA ++G K+ Q
Sbjct: 323 ALKQKMEGGIEEFKPPESNQKIN-ARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQ 381
Query: 662 CKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVS----QCESVASTVSAQEDEDIEAS 717
KNF+ NY+RR NL+ +LQ+ + + + D S + +S ++ S + ++ E +
Sbjct: 382 VKNFFVNYRRRFNLEEVLQEWEAEQGTQ-ASNGDASTLGEETKSASNVPSGKSTDEEEEA 440
Query: 718 NEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPS 762
+ P PS A +P L PT AP+
Sbjct: 441 QTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPA 485
>gi|8922733 REST corepressor 3 isoform d [Homo sapiens]
Length = 495
Score = 99.0 bits (245), Expect = 5e-20
Identities = 81/345 (23%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 436 FMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNY 495
F + WT +K +F+ F H K+F I L K++ V YYY KK + +L+ R
Sbjct: 85 FPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQA 144
Query: 496 GKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEK-------------- 541
K R+ Q E+ + + ++ KKE +K+ E+ +
Sbjct: 145 RKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSL 204
Query: 542 EDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAA 601
+ + + K + T+E A AN+ R+ S+ + A +
Sbjct: 205 QHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNS 264
Query: 602 AATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQ 661
A ++ + P S + + +RWT EE +A +G+ ++G+++ AIA ++G K+ Q
Sbjct: 265 ALKQKMEGGIEEFKPPESNQKIN-ARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQ 323
Query: 662 CKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVS----QCESVASTVSAQEDEDIEAS 717
KNF+ NY+RR NL+ +LQ+ + + + D S + +S ++ S + ++ E +
Sbjct: 324 VKNFFVNYRRRFNLEEVLQEWEAEQGTQ-ASNGDASTLGEETKSASNVPSGKSTDEEEEA 382
Query: 718 NEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPS 762
+ P PS A +P L PT AP+
Sbjct: 383 QTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPA 427
>gi|7661892 REST corepressor 1 [Homo sapiens]
Length = 482
Score = 95.5 bits (236), Expect = 6e-19
Identities = 75/291 (25%), Positives = 134/291 (46%), Gaps = 22/291 (7%)
Query: 436 FMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNY 495
F + WT +K +F+ F H K F I L KS+ V +YY KK +++ R+
Sbjct: 188 FPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDRH- 246
Query: 496 GKRRGRNQQIARPSQEEKVEEKEEDKAEKTE--KKEEEKKD-------EEEKDEKEDSKE 546
R Q+ R E+++EE + E + +E KK+ + K EK ++
Sbjct: 247 ----ARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEKHSTQA 302
Query: 547 NTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEE 606
+ K K ++E +A A + R+ S+ + +A E+
Sbjct: 303 KNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEK 362
Query: 607 PPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFY 666
+ P P + +RWT EE +A + + ++GR++ AI+ ++G KS Q KNF+
Sbjct: 363 LDGGIEPYRLPEVIQKCN-ARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFF 421
Query: 667 FNYKRRHNLDNLLQ----QHKQKTSRKPREERDVSQCESVASTVSAQEDED 713
NY+RR N+D +LQ +H ++ + P ++ V +S +++ E+ED
Sbjct: 422 VNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPV---KSPDNSIKMPEEED 469
Score = 49.3 bits (116), Expect = 5e-05
Identities = 32/145 (22%), Positives = 69/145 (47%), Gaps = 3/145 (2%)
Query: 628 WTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTS 687
WT E+ + ++ HG+ + I +M+ KS A FY+++K+ +++ +H +K
Sbjct: 192 WTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDRHARKQK 251
Query: 688 RKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNT 747
R+ E D + + + + + D++ E +++E P V VK + S + A +R
Sbjct: 252 REREESEDELEEANGNNPIDIEVDQNKE--SKKEVPPTETVPQVKKEKHSTQ-AKNRAKR 308
Query: 748 EPAVELEPTTETAPSTSPSLAVPST 772
+P + + E + S + +T
Sbjct: 309 KPPKGMFLSQEDVEAVSANATAATT 333
>gi|209977084 REST corepressor 3 isoform c [Homo sapiens]
Length = 449
Score = 93.2 bits (230), Expect = 3e-18
Identities = 71/299 (23%), Positives = 131/299 (43%), Gaps = 21/299 (7%)
Query: 436 FMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNY 495
F + WT +K +F+ F H K+F I L K++ V YYY KK + +L+ R
Sbjct: 143 FPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQA 202
Query: 496 GKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEK-------------- 541
K R+ Q E+ + + ++ KKE +K+ E+ +
Sbjct: 203 RKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSL 262
Query: 542 EDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAA 601
+ + + K + T+E A AN+ R+ S+ + A +
Sbjct: 263 QHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNS 322
Query: 602 AATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQ 661
A ++ + P S + + +RWT EE +A +G+ ++G+++ AIA ++G K+ Q
Sbjct: 323 ALKQKMEGGIEEFKPPESNQKIN-ARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQ 381
Query: 662 CKNFYFNYKRRHNLDNLLQQHKQKTSRKPRE------ERDVSQCESVASTVSAQEDEDI 714
KNF+ NY+RR NL+ +LQ+ + + + + +V S S E+E++
Sbjct: 382 VKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEV 440
Score = 38.9 bits (89), Expect = 0.063
Identities = 26/125 (20%), Positives = 55/125 (44%), Gaps = 23/125 (18%)
Query: 628 WTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTS 687
WT E+ + ++ HG+++ I +M+ K+ A +Y+++K+ + +L+ + +K +
Sbjct: 147 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLA 206
Query: 688 RKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNT 747
+ + D+D+ EE +P D P ++ A GNT
Sbjct: 207 NRHNQ---------------GDSDDDV----EETHPMDGNDSDYDPKKE----AKKEGNT 243
Query: 748 EPAVE 752
E V+
Sbjct: 244 EQPVQ 248
>gi|27734799 REST corepressor 2 [Homo sapiens]
Length = 523
Score = 85.5 bits (210), Expect = 6e-16
Identities = 78/340 (22%), Positives = 138/340 (40%), Gaps = 21/340 (6%)
Query: 436 FMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNY 495
F + WT +K +F+ F H K F I L K +P V YYY KK + +++ R
Sbjct: 131 FPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQA 190
Query: 496 GKRRGRNQQIARPSQEEK---VEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKD 552
+ GR + EE V E E D A+ + + + + ++ +
Sbjct: 191 RRLGGRKDKEDSDELEEGRGGVSEGEPDPADPKREPLPSRPLNARPGPGKKEVQVSQYRH 250
Query: 553 KIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAA----------ASAAAAA 602
T + +P G + R + ++ + +++
Sbjct: 251 HPLRTRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQ 310
Query: 603 ATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQC 662
A E PL PP SRWT +E +A + + +G+++ AIA+++G K+ Q
Sbjct: 311 ALEGGIDPLRPP----EANTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQV 366
Query: 663 KNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEEN 722
K F+ +Y+RR NL+ +LQ+ + + P + + A + +ED E + +
Sbjct: 367 KTFFVSYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEV--QITS 424
Query: 723 PEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPS 762
S +V P+ P TS ++P L P TAP+
Sbjct: 425 VSTSVPRSVPPAPPPPPPPTSL--SQPPPLLRPPLPTAPT 462
Score = 35.8 bits (81), Expect = 0.53
Identities = 43/200 (21%), Positives = 80/200 (40%), Gaps = 24/200 (12%)
Query: 628 WTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLL-QQHKQKT 686
WT E+ + ++ HG+ + I +M+ K +Y+++K+ + +++ +Q ++
Sbjct: 135 WTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLG 194
Query: 687 SRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGN 746
RK +E+ D + E VS E + + E P S +P E S+
Sbjct: 195 GRKDKEDSD--ELEEGRGGVSEGEPDPADPKRE---PLPSRPLNARPGPGKKEVQVSQYR 249
Query: 747 TEP---------AVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMD 797
P + L P TA S SP LA + + + + + S+ +
Sbjct: 250 HHPLRTRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLI------SLKRQVQSMKQ 303
Query: 798 VDQQEHSAEEGSVCDP--PP 815
+ A EG + DP PP
Sbjct: 304 TNSSLRQALEGGI-DPLRPP 322
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 80.5 bits (197), Expect = 2e-14
Identities = 92/415 (22%), Positives = 167/415 (40%), Gaps = 53/415 (12%)
Query: 511 EEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATP- 569
E+K EEKE+ K E +K+++ +EEK +KE+ K+ K++ K + E +E ++ TP
Sbjct: 647 EDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPP 706
Query: 570 ---------RGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEP--PPPLPPPPEPI 618
+K + + + + + +A +S + A + P +P E +
Sbjct: 707 KEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESV 766
Query: 619 STEPVETSRWTEE-EMEVAKK---------GLVEHGRNWAAIAKMVGTKSEAQCKNFYFN 668
+ V + E+ +++V KK V G AA+ G + K
Sbjct: 767 KKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAE 826
Query: 669 YKRRHNLDNLLQQHKQKTSRKPREERDVS-QCESVASTVSAQEDEDIEASNEEENPEDSE 727
+ ++L + ++ + + +D+ Q E + +E E +EA ++ E
Sbjct: 827 RSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQK-----E 881
Query: 728 VEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAED------ESVE 781
E K +SP+ + TE E E T E V + ED ES E
Sbjct: 882 REVTKGPAESPDEGIT--TTEGEGECEQTPEELEPVEKQ-GVDDIEKFEDEGAGFEESSE 938
Query: 782 T-QVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDN 840
T + E AE+ + D +EH S P ++ + + + E S GD+
Sbjct: 939 TGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDD 998
Query: 841 TKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPER 895
E D+D A EK E A++ E ++D + A + +E+ EPE+
Sbjct: 999 RAEEDMDEAIEKGE-------------AEQSEEEADEEDKAEDAREEEY--EPEK 1038
Score = 52.4 bits (124), Expect = 5e-06
Identities = 97/449 (21%), Positives = 166/449 (36%), Gaps = 44/449 (9%)
Query: 502 NQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEET 561
+++ A+ + + EK E A ++ EE+ + EK E E S+E E+DK + EE
Sbjct: 974 DEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEE 1033
Query: 562 EEREQATPRGR------KTANSQGRRK--GRITRSMTNEAAAASAAAAAATEEPPPPLPP 613
E E+ K A + G + G +T + T + A S A+ LP
Sbjct: 1034 YEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLT-TPTKQLGAQSPGREPASSIHDETLPG 1092
Query: 614 PPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQC-----KNFYFN 668
E +T E +R + E A G + ++ + S + N
Sbjct: 1093 GSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRDVMSDETNNEET 1152
Query: 669 YKRRHNLDNLLQQHKQKTSRKPREERDVSQCE--SVASTVSAQEDEDIEASNEEENPEDS 726
N+ + S++ + DV+ S S A + +D AS +P S
Sbjct: 1153 ESPSQEFVNITKYESSLYSQEYSKPADVTPLNGFSEGSKTDATDGKDYNASASTISPPSS 1212
Query: 727 EVE------AVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESV 780
E A++ + S A++ + + ++ + + +PS SPSL+ P E +
Sbjct: 1213 MEEDKFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSLSPSPPSPLEKTPL 1272
Query: 781 -ETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASK-VEG 838
E VN S+ T ++ V + E V P + V+ PE+ + V
Sbjct: 1273 GERSVNFSL---TPNEIKV------SAEAEVAPVSPEVTQEVVEEHCASPEDKTLEVVSP 1323
Query: 839 DNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSAD-EDVDGEPERQR 897
+ P DE ++ P + + S + D E ER
Sbjct: 1324 SQSVTGSAGHTPYYQSPTDEK-------SSHLPTEVIEKPPAVPVSFEFSDAKDENERAS 1376
Query: 898 MFPMDSK-PSLLNPTGSILVSSPLKPNPL 925
+ PMD P +P +L SPL+ PL
Sbjct: 1377 VSPMDEPVPDSESPIEKVL--SPLRSPPL 1403
Score = 34.3 bits (77), Expect = 1.5
Identities = 82/410 (20%), Positives = 138/410 (33%), Gaps = 65/410 (15%)
Query: 502 NQQIARPSQEEKVEEKEE-DKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEE 560
N+ ++ P E+ K D + +K EE + +E+D +S E T + G E
Sbjct: 1848 NRDLSTPGLEKDSGGKTPGDFSYAYQKPEETTRSPDEEDYDYESYEKTTRTSDVGGYYYE 1907
Query: 561 TEEREQATPR---------GRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPL 611
ER +P G+ T + T + +E+ P
Sbjct: 1908 KIERTTKSPSDSGYSYETIGKTTKTPEDGDYSYEIIEKTTRTPEEGGYSYDISEKTTSP- 1966
Query: 612 PPPPEPISTEPVETSRWTEEEM-------EVAKKGLVEHGRNWAAIAKMVG-TKSEAQCK 663
P S E E SR +++ E L + ++ K+ +SE
Sbjct: 1967 -PEVSGYSYEKTERSRRLLDDISNGYDDSEDGGHTLGDPSYSYETTEKITSFPESEGYSY 2025
Query: 664 NFYFNYKRRHNLDNLLQQHKQKTSRKPR------EERDVSQCESVASTVSAQEDEDI--- 714
R + + +K +R P+ E D+ S A++D D+
Sbjct: 2026 ETSTKTTRTPDTSTYCYETAEKITRTPQASTYSYETSDLCYTAEKKSPSEARQDVDLCLV 2085
Query: 715 ----------EASNEEENPEDSE-VEAVKPSEDSPENATSRGNTEPAV----------EL 753
E S NP E + +P+E+S + T G P E
Sbjct: 2086 SSCEYKHPKTELSPSFINPNPLEWFASEEPTEESEKPLTQSGGAPPPPGGKQQGRQCDET 2145
Query: 754 EPTT--ETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVC 811
PT+ E+APS + S P T+ + + ++ +ET +H
Sbjct: 2146 PPTSVSESAPSQTDSDVPPETEECPSITADANIDSEDESETIPTDKTVTYKH-------M 2198
Query: 812 DPPPATKAD------SVDVEVRVPENHASKVEGDNTKERDLDRASEKVEP 855
DPPPA D DV + PE A + ++DL ++ +P
Sbjct: 2199 DPPPAPVQDRSPSPRHPDVSMVDPEALAIEQNLGKALKKDLKEKTKTKKP 2248
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 74.7 bits (182), Expect = 1e-12
Identities = 368/1863 (19%), Positives = 620/1863 (33%), Gaps = 258/1863 (13%)
Query: 696 VSQCESVASTVSAQEDEDIEASNEEENP---EDSEVEAVKPSEDSPENATSRGNTEPAVE 752
VS + ST + AS E + E S + PSE SP + +T P
Sbjct: 1586 VSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVAS 1645
Query: 753 LEPTT-ETAPSTSPSLAVPSTK------PAEDESVETQV----NDSISAETAEQMDVDQQ 801
E +T T P S S + ST+ PAE S+ T +++ T V
Sbjct: 1646 PEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASS 1705
Query: 802 EHSAEEGSVCD-PPPATKADSVDVEVRVPEN----HASKVEGDNTKERDLDRASEKVEPR 856
S + D P T + E +++ EG T + ++ V
Sbjct: 1706 AISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEG-TTPLTSIPVSTTPVLSS 1764
Query: 857 DEDLVVAQQINAQRPEPQS-DNDSSATCSADEDVDGEPERQRMFPMDSKPS----LLNPT 911
+ + A I+ P S + SS T + + + M P+ S P + N
Sbjct: 1765 EASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSE 1824
Query: 912 GSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESA 971
S L ++P+ N V VS +P TP G ++ + +A
Sbjct: 1825 ASTLSTTPVDSNS---------PVVTSTAVSSSP------TPAEGTSI-ATSTPSEGSTA 1868
Query: 972 LLEEQRQRQEQIDLECRS-STSPCGTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPT 1030
L E + ST+P TS +P + + +P +G +PT+ P
Sbjct: 1869 LTSIPVSTTTVASSETNTLSTTPAVTS-TPVTTYAQVSSSP-----TTADGSSMPTSTPR 1922
Query: 1031 RPPPPL--IPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQAS--------YTQETPK 1080
PPL IP S TTVAS + + + TP +T+++QAS + TP
Sbjct: 1923 EGRPPLTSIPVSTTTVASSEINTLSTTLADTRTP---VTTYSQASSSPTTADGTSMPTPA 1979
Query: 1081 PSVGSISL-GLPRQQE---SAKSATLPYIKQEEFSPRSQNSQ------------------ 1118
S GS L +P S++++TL + +P + +++
Sbjct: 1980 YSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTP 2039
Query: 1119 ----------PEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSI-TQ 1167
P + EG T + +T T S + S+ S ++
Sbjct: 2040 SERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSE 2099
Query: 1168 GTP---ALPQTGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDN 1224
G+P ++P + P + ++S P++ +SP E +S + EG S +Y +
Sbjct: 2100 GSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSS-SPIPTEGTSMQTSTYSD 2158
Query: 1225 IKNAREGTRSPRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHS 1284
R+P T+ +S S + +PV+ E R+ P S +
Sbjct: 2159 -------RRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTE---ARSSPTTSEGT 2208
Query: 1285 DLKERTVLSGSI------MQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPY 1338
+ T GS + P T+E+ S P+ A +
Sbjct: 2209 SMPTSTPSEGSTPFTSMPVSTMPVVTSEA----STLSATPVDTSTPVTTSTEATSSPTTA 2264
Query: 1339 DG----ITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNS 1394
+G +T+ E + IP L S + ST P + TP F ++
Sbjct: 2265 EGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVS---TLSTTP-----VDSNTP--FTTST 2314
Query: 1395 GQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSS 1454
S+ + S S G PL +P + + V S TS +S+
Sbjct: 2315 EASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTM--------------VASFETSTLST 2360
Query: 1455 GPSVLRSTLHEAPKAQLSPGIYDDTSARRTPVSYQNTMSRGSPM-----------MNRTS 1503
P+ + + +A SP DDTS + S +T P+ + T+
Sbjct: 2361 TPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTT 2420
Query: 1504 DVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVYRSH 1563
V S+ +T+ E S+ T + SIP P G P+ S S AG + +
Sbjct: 2421 PVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTP 2480
Query: 1564 LPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQL----YAMENTRQTILNDYIT 1619
+ T + P A + + + G + + + + L+
Sbjct: 2481 VDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPV 2540
Query: 1620 SQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPT---ILVPHPGGTSTPPMD 1676
V +++ + E + G L +MP + + ST P+D
Sbjct: 2541 DSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVD 2600
Query: 1677 -RITYIPGTQITFPPRPYNSASMSPGHPTHLAAAAS---------AEREREREREKERER 1726
I T+ + P SM P+ ++ + + A E +
Sbjct: 2601 TSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDT 2660
Query: 1727 ERIAAASSDLYLRP----GSEQP-GRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGT 1781
+ S+ P GS P PG +P ++ T+L + T
Sbjct: 2661 RTLVTTSTGTSSSPTTAEGSSMPTSTPGERS---TPLTNILVSTTLLANSEASTLSTTPV 2717
Query: 1782 SVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKE 1841
TP+ +A+ P A G S+ R +T +D L S + V+ ++
Sbjct: 2718 DTSTPVTTSAEASSSPTTAEGTSM-------RISTPSDGSTPLTSILVST--LPVASSEA 2768
Query: 1842 SKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYS 1901
S ++ ++ S + T EV +S + P H+ V S
Sbjct: 2769 STVSTTAVDTSI---PVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASS 2825
Query: 1902 EAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSL 1961
EAG P + T+ ++ T A I V I+ ++ +SS
Sbjct: 2826 EAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSE 2885
Query: 1962 SSHRYETPSD-AIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQY---EGPLHHY 2017
+S TP D +I V + + P T P + + P P+
Sbjct: 2886 ASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMP--ISTPSEVSTPLTSILVSTVPVAGS 2943
Query: 2018 RPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPP 2077
S +P P + + P T ++ I T R ++S + P
Sbjct: 2944 EASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSM-----PISTPGERRTPLTSMSVSTMP 2998
Query: 2078 -----TSTFQNSPSALVSTPVRTKTSNRYSP-ESQAQSVHHQRPGSRVSPENLVDKSRGS 2131
ST +P A STPV T T SP ++ + P +P + S +
Sbjct: 2999 VASSEASTLSRTP-ADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVS--T 3055
Query: 2132 RPGKSPERSHVSSEPYEPISP-------PQVPVVHEKQDSLLLLSQRGAEPAEQRNDARS 2184
P PE S +S+ P + SP P E + G+ P + +
Sbjct: 3056 TPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTT 3115
Query: 2185 PGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTS 2244
P + S + + T +TS V + + S G ++ T + +P V+T
Sbjct: 3116 PVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMP-VSTM 3174
Query: 2245 GSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPM-GVVPGT----ANT 2299
VSS + + A+ + + + + E + S P G+ P T +NT
Sbjct: 3175 LVVSSEDSTLS--ATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNT 3232
Query: 2300 SVVTSG---------------ETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQGY 2344
V +S T E P + G P S + +P+
Sbjct: 3233 PVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMP----TSTPSEGSTPLTSMPV 3288
Query: 2345 LGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSS---TGSTQFPYN-------PLTMRMLS 2394
T SS +S S TP + SS T P + PLT S
Sbjct: 3289 STTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFS 3348
Query: 2395 STP 2397
+TP
Sbjct: 3349 TTP 3351
Score = 73.6 bits (179), Expect = 2e-12
Identities = 321/1650 (19%), Positives = 537/1650 (32%), Gaps = 263/1650 (15%)
Query: 589 MTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWA 648
+T+ A++S A T P P+++ P T EM V+
Sbjct: 307 ITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVD------ 360
Query: 649 AIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCE-SVASTVS 707
+ +V T +E + + L + L + + P V+ E S ST+
Sbjct: 361 -TSTLVTTSTEPS--SLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIP 417
Query: 708 AQEDEDI----EASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEP-------- 755
+ EAS+ ED+ + PSE S + +T P E
Sbjct: 418 VDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPV 477
Query: 756 ------TTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGS 809
TT T S+SP A ++ P S + S+S T M V E S +
Sbjct: 478 DSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVST---MPVASSEASTLSTT 534
Query: 810 VCD-PPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINA 868
D P T + PE + + E + V R LVV+ + +
Sbjct: 535 PVDTSTPVTTSSEASSSSTTPE--GTSIPTSTPSEGSTPLTNMPVSTR---LVVSSEAST 589
Query: 869 QRPEPQSDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPL----KPNP 924
P +D+++ T S++ P + S+ VS+ L + +
Sbjct: 590 TSTTP-ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEAST 648
Query: 925 LDLPQLQHRAAVIPPMVSCTPCNIPIGT--PVSGYALYQRHIKAMHESALLEEQRQRQEQ 982
L + V + + GT P S Y + +M + L +
Sbjct: 649 LSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEAS-- 706
Query: 983 IDLECRSSTSPCGTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPL--IPSS 1040
ST+P TS E +G +PT+ P+ PL +P S
Sbjct: 707 -----TLSTTPVDTSTPVTTSTEASSS------PTTADGASMPTSTPSEGSTPLTSMPVS 755
Query: 1041 KTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSA 1100
KT + S + S + S + T++T+ +AS + T +
Sbjct: 756 KTLLTSSEASTL---STTPLDTSTHITTSTEASCSPTT------------------TEGT 794
Query: 1101 TLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPS 1160
++P E SP S P + E T +T T S + +
Sbjct: 795 SMPISTPSEGSP-LLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGT 853
Query: 1161 LRGSITQGTPALPQTGIPTEALVK-----GSISRMPIEDSSPEKGREEAASKGHVIYEGK 1215
+ T P T +P + ++S P++ S+P
Sbjct: 854 SMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTP------------------ 895
Query: 1216 SGHILSYDNIKNAREGTRSPRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLI-C 1274
+ N+ E SP T+ +G SM P S P EG
Sbjct: 896 ---------VTNSTEARSSPTTS-----------------EGTSM---PTSTPGEGSTPL 926
Query: 1275 RALPRG-SPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAIT 1333
++P +P + RT+ + + TP T+ + S P A +I
Sbjct: 927 TSMPDSTTPVVSSEARTLSATPVDTSTPVTTS------------TEATSSPTTAEGTSIP 974
Query: 1334 KGKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNN 1393
P +G T + S + + T + TP V S P+ + + P +
Sbjct: 975 TSTPSEGTTPLTSTPVSHTLVANSEASTLST--TP--VDSNTPLTTSTEASSPPPTAEGT 1030
Query: 1394 SGQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVS 1453
S + S S G PL +P + +V E T T V +
Sbjct: 1031 SMPT-------------STPSEGSTPLTRMPVSTTMV--ASSETSTLSTTPADTSTPVTT 1075
Query: 1454 SGPSVLRSTLHEAPKAQLSPGIYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKST 1513
+ ST + S T PVS + +S + ++ T+ V S +T
Sbjct: 1076 YSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLS-TTPVDTSIPVTT 1134
Query: 1514 NHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMP 1573
+ E S+ T + SIP P G P+ S S A + + + + A
Sbjct: 1135 STEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATS 1194
Query: 1574 FHRALDPAAAAYLFQ------RQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQM---- 1623
+ P A + +P P ++ A + TS +
Sbjct: 1195 TEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSA 1254
Query: 1624 QVNLRPDVARGLSPREQPLGLPYPAT-RGIIDLTNMP-PTILVPHPGGTS--TPPMD-RI 1678
+ + P A G S LP T G LT++P T LV P ++ T P+D +
Sbjct: 1255 ETSSSPTTAEGTS-------LPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKG 1307
Query: 1679 TYIPGTQITFPPRPYNSASM-----SPGHP--------THLAAAASAEREREREREKERE 1725
+ +++ P P SM S G T L A+++ +
Sbjct: 1308 PVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTP 1367
Query: 1726 RERIAAASSDLYLRPGSEQPGRPGSHGYVR------SPSPSVRTQETMLQQRPSVFQGTN 1779
A S G+ P S G S +P V ++ + L P
Sbjct: 1368 VTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPG 1427
Query: 1780 GTSVITPLDPTAQLRI---MPLPAGGPSISQGLPASRYNTAADALAAL--VDAAASAPQM 1834
TS PT I P+ G + + +P S A + L +++P +
Sbjct: 1428 TTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVV 1487
Query: 1835 DVSKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQP 1894
+ S A + + S + + T V + L T+ A S
Sbjct: 1488 TSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTT 1547
Query: 1895 HSSVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDK-----DARE 1949
+S S D S Y E G T +T+ +++ A+ D++
Sbjct: 1548 YSQASSSPTTADGTSMQTSTYSE-----GSTPLTSLPVSTMLVVSSEANTLSTTPIDSKT 1602
Query: 1950 RGSQSSDSSSSL----SSHRYETPSDAIEVIS--PASSPAPPQEKLQTYQPEVVKANQAE 2003
+ + S+++SSS SS TPS+ +++ P S+ + T V +N
Sbjct: 1603 QVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPV 1662
Query: 2004 NDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDF 2063
T P +P+ +P S+ E G+ P T + T
Sbjct: 1663 ITSTEVSSSP---------TPAEGTSMPTSTYTE--GRTPLTS---------ITVRTTPV 1702
Query: 2064 ARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNRYSP-ESQAQSVHHQRPGSRVSPE 2122
A + +S+ + T+ N STPV T T R SP S+ S+ + P +P
Sbjct: 1703 ASSAISTLS-----TTPVDN------STPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPL 1751
Query: 2123 NLVDKSRGSRPGKSPERSHVSSEPYEPISP 2152
+ S + P S E S +S+ P + +P
Sbjct: 1752 TSIPVS--TTPVLSSEASTLSATPIDTSTP 1779
Score = 70.1 bits (170), Expect = 3e-11
Identities = 308/1546 (19%), Positives = 485/1546 (31%), Gaps = 207/1546 (13%)
Query: 687 SRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGN 746
S P + S + S EAS+ PE + + PSE S +
Sbjct: 519 STMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVS 578
Query: 747 TEPAVELE-PTTETAPS------TSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVD 799
T V E TT T P+ T+ S A S+ AE S+ T S T M V
Sbjct: 579 TRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTY-SERGTTITSMSVS 637
Query: 800 QQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVE--PRD 857
++ E S P V + ++ EG + S + P +
Sbjct: 638 TTLVASSEASTLSTTPVDSNTPVTTSTEATSS-STTAEGTSMPTSTYTEGSTPLTSMPVN 696
Query: 858 EDLVVAQQINAQRPEPQSDN----DSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGS 913
LV + + + P + S+ S+ DG S P P
Sbjct: 697 TTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSK 756
Query: 914 ILV----SSPLKPNPLDLPQLQHRAAVIPPMVSCTP-----CNIPIGTPVSGYALYQ--- 961
L+ +S L PLD SC+P ++PI TP G L
Sbjct: 757 TLLTSSEASTLSTTPLD----TSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIP 812
Query: 962 ---RHIKAMHESALLEEQRQRQEQIDLECRSSTSPC---GTSKSPNREWEVLQPAPHQVI 1015
+ + S L + S+SP GTS + E P +
Sbjct: 813 VSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPV 872
Query: 1016 TNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPG---TYLTSHNQA 1072
+ +T T P P + +T A P+ G S+ TPG T LTS +
Sbjct: 873 STTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDS 932
Query: 1073 S---YTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLVR--AQ 1127
+ + E S + P S ++ + P + P S S+ L
Sbjct: 933 TTPVVSSEARTLSATPVDTSTP-VTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVS 991
Query: 1128 HEGVVRGTAGAIQEGSITRGTP--TSKISVESIPSLRG-SITQGTP---ALPQTGIPTEA 1181
H V A + + TP TS + P+ G S+ TP + P T +P
Sbjct: 992 HTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVST 1051
Query: 1182 LVKGS-----ISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDN------------ 1224
+ S +S P + S+P +A+S +G S +Y
Sbjct: 1052 TMVASSETSTLSTTPADTSTPVTTYSQASSSS-TTADGTSMPTSTYSEGSTPLTSVPVST 1110
Query: 1225 ---------------------IKNAREGTRSPRTAHEISLKRSYESVEGNIKQGMSMRES 1263
+ + E + SP TA S+ S S EG +
Sbjct: 1111 RLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPS-EGT----TPLASM 1165
Query: 1264 PVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYPKQIKRESP 1323
PVS L + A + D K + S P A S + S
Sbjct: 1166 PVSTTLV-VSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSM 1224
Query: 1324 PIR-----AFEGAITKGKPYD---GITTIKEMGRSIHEIPRQDILTQESRKTPEVVQS-- 1373
P+R + E + P D +TT E S + T + + ++ S
Sbjct: 1225 PVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIP 1284
Query: 1374 ------TRP----IIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIV 1423
T P ++ + P+ N S S+ T S S G PL +
Sbjct: 1285 VSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPT--STYSEGRTPLTSI 1342
Query: 1424 PENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARR 1483
P N +V + T T V +S + T E S T
Sbjct: 1343 PVNTTLVASSAISILST--TPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTS 1400
Query: 1484 TPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPV-- 1541
PVS +S + ++ T V S+ +T+ E S+ T + SIP +P G P+
Sbjct: 1401 IPVSTTPVVSSEASTLSAT-PVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKS 1459
Query: 1542 --VSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPG--- 1596
VS++P + + S+ P A+ + P A +P+ G
Sbjct: 1460 IPVSNTPVANSEASTLSTTPVDSNSPVVTSTAV----SSSPTPAEGTSIAISTPSEGSTA 1515
Query: 1597 ---YPSQYQLYAMENTRQTILNDYITSQQM----QVNLRPDVARGLSPREQPLGLPYPAT 1649
P A +TS + Q + P A G S + +
Sbjct: 1516 LTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTY------S 1569
Query: 1650 RGIIDLTNMP-PTILV--PHPGGTSTPPMDRITYI------------PGTQITFPPRPYN 1694
G LT++P T+LV ST P+D T + G+ +T P
Sbjct: 1570 EGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTI-STPSE 1628
Query: 1695 SASMSPGHPTHLAAAASAEREREREREKERERERIAA--ASSDLYLRPGSEQPGRPGSHG 1752
+ + P AS E + I + SS G+ P + G
Sbjct: 1629 GSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEG 1688
Query: 1753 YVRSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPAS 1812
R+P S+ + T + T TP+ + + R P + G S+ P+
Sbjct: 1689 --RTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPS- 1745
Query: 1813 RYNTAADALAALVDAAASAPQMDVSKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLE 1872
+ + VS T EA+ L S V+ +
Sbjct: 1746 -------------EGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTT 1792
Query: 1873 VEKRSVQCLYTSSAFP--SGKPQPHSSVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAA 1930
E S+ S + P H+ V SEA P S T ++ T A
Sbjct: 1793 AEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPA 1852
Query: 1931 NFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDA-IEVISPASSPAPPQEKL 1989
+ S S+ S++L+S T + A E + +++PA +
Sbjct: 1853 EGTSIAT--------------STPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPV 1898
Query: 1990 QTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLI 2049
TY Q + PT + P++ P P +P S+ ++
Sbjct: 1899 TTYA-------QVSSSPTTADGSSMPTSTPREGRP-PLTSIPVSTTTVASSEINTLS--T 1948
Query: 2050 TLADHICQIITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRT 2095
TLAD + T A + ++ PT + + L S P+ T
Sbjct: 1949 TLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLST 1994
Score = 67.8 bits (164), Expect = 1e-10
Identities = 331/1694 (19%), Positives = 551/1694 (32%), Gaps = 225/1694 (13%)
Query: 686 TSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRG 745
T P E R S+ S ++T+ ED ++ PE ++V PSE+S + +
Sbjct: 108 TRMTPTESRTTSESTSDSTTLFPSSTED---TSSPTTPEGTDVPMSTPSEESISSTMAFV 164
Query: 746 NTEPAVELEP--------------TTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAE 791
+T P E TT T S+SP+ +T P S + S+ A
Sbjct: 165 STAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPAS 224
Query: 792 TAEQMDVDQQEHSAEEGSVCDPPP-ATKADSVDVEVRVPENHASKVEGDNTKERDLDRAS 850
T + + + P + +A S P S G +T +
Sbjct: 225 TMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRM---- 280
Query: 851 EKVEPRDEDLVVAQQINAQRPEPQSDN---------DSSATCSADEDVDGEPERQRMFPM 901
P LVV+ + + P + N SS T + + + P+
Sbjct: 281 ----PLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPL 336
Query: 902 DSKPSLLNPTG----SILVSSPL--------KPNPLDLPQLQHRAAVIPPMVS--CTP-C 946
S P+ P S L +P+ P LP +++ +S TP
Sbjct: 337 TSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLT 396
Query: 947 NIPIGT--------------PVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTS 992
N+P+ T PV +A E+ TS
Sbjct: 397 NMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTS 456
Query: 993 -PCGTSKSPNREWEVLQPAP----HQVITN--------LPEGVRLPTTRPTRPPPPLIPS 1039
P T+ + E L P QV T+ E +PT+ P+ PL
Sbjct: 457 MPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSM 516
Query: 1040 SKTT--VASEKPSFIMGGSISQGTPGTYLTSHNQASYTQE-----TPKPSVGS------- 1085
S +T VAS + S + + TP T + + +S T E T PS GS
Sbjct: 517 SVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMP 576
Query: 1086 ISLGLPRQQESAKSATLP------YIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAI 1139
+S L E++ ++T P E S S ++ + E RGT
Sbjct: 577 VSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSE---RGTTITS 633
Query: 1140 QEGSITRGTPTSKISVESIP-------SLRGSITQGTPALPQTGIPTEALVKGS--ISRM 1190
S T + ++ + P + T + T +PT +GS ++ M
Sbjct: 634 MSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSM 693
Query: 1191 PIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLKRSYESV 1250
P+ + S + + + + + E + SP TA S+ S S
Sbjct: 694 PVNTTLVASSEASTLS---------TTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSE 744
Query: 1251 EGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFED 1310
M + ++ +++ + S H S + +GT + E
Sbjct: 745 GSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSE- 803
Query: 1311 GLKYPKQIKRESPPIRAFEGAITKGKPYDG---ITTIKEMGRS--IHEIPRQDILTQESR 1365
G I P+ + E + P D +TT E+ S E T
Sbjct: 804 GSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEG 863
Query: 1366 KTP--EVVQSTRPIIEGSIS--------QGTPIKFDNNSGQSAIKHNVKSLITGPSKLSR 1415
+TP + ST + +IS TP+ + S S+ T S
Sbjct: 864 RTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT--STPGE 921
Query: 1416 GMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGI 1475
G PL +P++ V + + A T T V +S + T E S
Sbjct: 922 GSTPLTSMPDSTTPVVSSEARTLSA--TPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPS 979
Query: 1476 YDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPV 1535
T TPVS+ + + ++ T+ V ++ +T+ E S + S+P +P
Sbjct: 980 EGTTPLTSTPVSHTLVANSEASTLS-TTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPS 1038
Query: 1536 PGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTP 1595
G P+ P A + T D + P ++++ PT
Sbjct: 1039 EGSTPLTRM----PVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTS 1094
Query: 1596 GYP--SQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQP-----LGLP-YP 1647
Y S +TR + ++ T V+ V P +P P
Sbjct: 1095 TYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSP 1154
Query: 1648 ATRGIIDLTNMP--PTILVPHPGGT-STPPMDRITYI-PGTQITFPPRPYNSASMSPGHP 1703
+ G L +MP T++V T ST P+D T + T+ + PP SM P
Sbjct: 1155 PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTP 1214
Query: 1704 THLAAAASAERERERE-REKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVR 1762
+ ++ R E + + + +E P + P+ +
Sbjct: 1215 GERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTS 1274
Query: 1763 TQETMLQQRP----SVFQGTNGTSVITPLD------PTAQLRIMPLPAGGPSI-----SQ 1807
T+L P V T + TP+D + ++ P PA G S+ S+
Sbjct: 1275 EGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSE 1334
Query: 1808 G------LPASRYNTAADALAAL----VDAAASAPQMDVSKTKESKHEAARLEEN----- 1852
G +P + A+ A++ L VD + + + + E + +
Sbjct: 1335 GRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEG 1394
Query: 1853 ---LRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGP 1909
L S + + E TL T+SA + P + + +G
Sbjct: 1395 TTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGK 1454
Query: 1910 PPKSRY--------EEELRTRGKTTITAANFIDVIITRQIASDKDARERG-----SQSSD 1956
P E T T + + + ++T S G S S+
Sbjct: 1455 TPLKSIPVSNTPVANSEASTLSTTPVDSNS---PVVTSTAVSSSPTPAEGTSIAISTPSE 1511
Query: 1957 SSSSLSSHRYETPSDA-IEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLH 2015
S++L+S T + A E+ S +++PA + TY +QA + PT +G
Sbjct: 1512 GSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTY-------SQASSSPTTA-DGTSM 1563
Query: 2016 HYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQ 2075
E +P LP S+ + TL+ TQ A + SS T +
Sbjct: 1564 QTSTYSEGSTPLTSLPVSTMLVVSSEAN------TLSTTPIDSKTQVTASTEASSSTTAE 1617
Query: 2076 PPTSTFQN-SPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPG 2134
+ T S + + T + T+ SPE+ S S V V S G
Sbjct: 1618 GSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEG 1677
Query: 2135 KSPERSHVSS--EPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLP 2192
S S + P I+ PV +L + P +ARS + S
Sbjct: 1678 TSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGT 1737
Query: 2193 SF--FTKLENTSPM 2204
S T E T+P+
Sbjct: 1738 SMPNSTPSEGTTPL 1751
Score = 66.6 bits (161), Expect = 3e-10
Identities = 353/1851 (19%), Positives = 604/1851 (32%), Gaps = 232/1851 (12%)
Query: 701 SVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPA-VELEPTTET 759
S T SA+ + P + E P + P + T N+E + + P
Sbjct: 1424 STPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSN 1483
Query: 760 APSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKA 819
+P + + S PAE S+ S + + V ++ E + PA +
Sbjct: 1484 SPVVTSTAVSSSPTPAEGTSIAIST-PSEGSTALTSIPVSTTTVASSEINSLSTTPAVTS 1542
Query: 820 DSVDVEVRVPENHASKVEGDNTKERDLDRASEKVE--PRDEDLVVAQQINAQRPEPQSDN 877
V + + + +G + + S + P LVV+ + N P D+
Sbjct: 1543 TPVTTYSQASSSPTT-ADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTP-IDS 1600
Query: 878 DSSATCSADEDVDGEPERQRMF---PMDSKPSLLN-PTGSILVSSPLKPNPLDLPQLQHR 933
+ T S + E M P + P L + P + V+SP P +
Sbjct: 1601 KTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNS 1660
Query: 934 AAVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSP 993
+ VS +P TP G ++ R ST+P
Sbjct: 1661 PVITSTEVSSSP------TPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTP 1714
Query: 994 CGTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPL--IPSSKTTVASEKPSF 1051
S E + +P EG +P + P+ PL IP S T V S + S
Sbjct: 1715 VDNSTPVTTSTEA-RSSP-----TTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEAST 1768
Query: 1052 IMGGSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFS 1111
+ I TP T T + T E ++S G+ + S TL + E S
Sbjct: 1769 LSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTL--VANSEAS 1826
Query: 1112 -----PRSQNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTS-KISVESIPSLRGSI 1165
P NS + GT+ A S TS +S ++ S +
Sbjct: 1827 TLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNT 1886
Query: 1166 TQGTPALPQTGIPTEALVKGSI-----SRMPIEDSSPEKGREEAASKGHVIYEGKSGHIL 1220
TPA+ T + T A V S S MP S+P +GR S S I
Sbjct: 1887 LSTTPAVTSTPVTTYAQVSSSPTTADGSSMPT--STPREGRPPLTSIPVSTTTVASSEI- 1943
Query: 1221 SYDNIKNAREGTRSPRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLI-CRALPR 1279
+ + TR+P T + S S G SM P A EG ++P
Sbjct: 1944 --NTLSTTLADTRTPVTTY------SQASSSPTTADGTSM---PTPAYSEGSTPLTSMPL 1992
Query: 1280 GSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYPK-----QIKRESPPIRAFEGAITK 1334
+ E + LS + + + ATT + +G P I+ +P R A
Sbjct: 1993 STTLVVSSEASTLSTTPVDTSTPATTST--EGSSSPTTAGGTSIQTSTPSERTTPLA--- 2047
Query: 1335 GKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTR--------------PIIEG 1380
G P + G ++ P D TQ + T +T P++
Sbjct: 2048 GMPVSTTLVVSSEGNTLSTTP-VDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTS 2106
Query: 1381 SISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYEDVKA 1440
TP+ S S + S + +++S P E ++ Y D +
Sbjct: 2107 IPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTS-----MQTSTYSDRRT 2161
Query: 1441 GETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRTPVSYQNT-MSRGSPMM 1499
T T+VV+S STL P +P + + T AR +P + + T M +P
Sbjct: 2162 PLTSMPVSTTVVASSAI---STLSTTPVDTSTP-VTNSTEARSSPTTSEGTSMPTSTPSE 2217
Query: 1500 NRT----------------------SDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPG 1537
T + V S+ +T+ E S+ T + SIP + G
Sbjct: 2218 GSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEG 2277
Query: 1538 VDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGY 1597
P+ S P A + T +D PF + + ++ + PT
Sbjct: 2278 TTPLTSI----PVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTS 2333
Query: 1598 PSQYQLYAMENTRQTILNDYITSQQMQVNLRP-DVARGLSPREQPLGLPYPA-------- 1648
T++ + TS ++ P D + ++ Q P A
Sbjct: 2334 SEGNTPLTRMPVSTTMVASFETST---LSTTPADTSTPVTTYSQAGSSPTTADDTSMPTS 2390
Query: 1649 --TRGIIDLTNMPPTIL--VPHPGGT-STPPMDRITYIP-GTQITFPPRPYNSASMSPGH 1702
+ G LT++P + + V T ST P+D T + T+ + P S+
Sbjct: 2391 TYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSP 2450
Query: 1703 PTH-LAAAASAEREREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSV 1761
P+ AS E + + +E P + + P +
Sbjct: 2451 PSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTA 2510
Query: 1762 RTQETMLQQRP----SVFQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQG--LPASRYN 1815
T+L P V T TP+D + + + + ++G +P S Y+
Sbjct: 2511 SEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYS 2570
Query: 1816 ----------TAADALAALVDAAASAPQMDVSKTKESKHEAARLEENLRSRSAAVSEQQQ 1865
+ LA+ + S +D S + E + + S +S +
Sbjct: 2571 EGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSE 2630
Query: 1866 LEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYEEELRTRGKT 1925
+ + ++ + ++ S P ++V + G P T G+
Sbjct: 2631 VSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGER 2690
Query: 1926 TITAANFIDVIITRQIASDKDARERGSQSSDSSSSLS---------------SHRYETPS 1970
+ N ++++ + ++ +A + D+S+ ++ S R TPS
Sbjct: 2691 STPLTN---ILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPS 2747
Query: 1971 DA--------IEVISPASSPAPPQEK--LQTYQPEVVKANQAENDPTRQYEGPLHHYRPQ 2020
D + + ASS A + T P V + +A + PT + P
Sbjct: 2748 DGSTPLTSILVSTLPVASSEASTVSTTAVDTSIP-VTTSTEASSSPTTAEVTSMPTSTPS 2806
Query: 2021 QESPSPQQQLP------PSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQ 2074
+ S +P +P SS+A + P D + T A + ++
Sbjct: 2807 ETS-TPLTSMPVNHTPVASSEAGTLSTTP--------VDTSTPVTTSTKASSSPTTAEGI 2857
Query: 2075 QPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPG 2134
P ST + L S PV T S+A ++ S + + + +
Sbjct: 2858 VVPISTASEGSTLLTSIPVSTTPV----ASSEASTL------STTPVDTSIPVTTSTEGS 2907
Query: 2135 KSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSF 2194
SP + +S P S P+ ++ + + + D R+P + S S
Sbjct: 2908 SSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASS 2967
Query: 2195 FTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSF 2254
+ M S E L S +A+++ T + PA TS V++ +
Sbjct: 2968 SPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEAST-LSRTPA-DTSTPVTTSTEAS 3025
Query: 2255 ADPASNLGLEDIIRKALMGS-----FDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRR 2309
+ P + G I GS + + + P +N+ VVTS E
Sbjct: 3026 SSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEV-- 3083
Query: 2310 EEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTP-- 2367
P+P G + S + +P+ G T SS S S TP
Sbjct: 3084 -SSSPTPAEG-----TSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVT 3137
Query: 2368 -------------GWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTPIACAP 2405
G + S GST Y P++ ++ S+ + ++ P
Sbjct: 3138 TSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATP 3188
Score = 58.5 bits (140), Expect = 8e-08
Identities = 290/1535 (18%), Positives = 480/1535 (31%), Gaps = 220/1535 (14%)
Query: 715 EASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKP 774
EAS P D+ + +E S T+ G + P T+ + T+P ++P
Sbjct: 1117 EASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIP------TSPPSEGTTPLASMP---- 1166
Query: 775 AEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHAS 834
V T + S A T VD + A PPP + S+ P ++
Sbjct: 1167 -----VSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTST--PGERST 1219
Query: 835 KVEG---DNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDG 891
+ +T + ++ P D V ++ S T + E
Sbjct: 1220 PLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEG--- 1276
Query: 892 EPERQRMFPMDSKPSLLN--PTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIP 949
+LL P + LV+SP L P V VS +P
Sbjct: 1277 -------------STLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAE 1323
Query: 950 IGT--PVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWEVL 1007
GT P S Y+ + + ++ + L I + ST+P S E
Sbjct: 1324 -GTSMPTSTYSEGRTPLTSIPVNTTLVAS----SAISI---LSTTPVDNSTPVTTSTEAC 1375
Query: 1008 QPAPHQVITNLPEGVRLPTTRPTRPPPPL--IPSSKTTVASEKPSFIMGGSISQGTPGTY 1065
EG +P + P+ PL IP S T V S + S + + TPGT
Sbjct: 1376 SSP------TTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTT 1429
Query: 1066 LTSHNQASYTQE-----TPKPSVGSISLGLPRQQESAKSATLPYIKQE----EFSPRSQN 1116
+ T E T PS G L +S + P E +P N
Sbjct: 1430 SAEATSSPTTAEGISIPTSTPSEGKTPL------KSIPVSNTPVANSEASTLSTTPVDSN 1483
Query: 1117 SQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTS-KISVESIPSLRGSITQGTPALPQT 1175
S + GT+ AI S TS +S ++ S + TPA+ T
Sbjct: 1484 SPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTST 1543
Query: 1176 GIPTEALVKGSISRMP---IEDSSPEKGREEAASK--GHVIYEGKSGHILSYDNIKNARE 1230
+ T + S + ++ S+ +G S ++ + LS I + +
Sbjct: 1544 PVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQ 1603
Query: 1231 GTRSPR-----TAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSD 1285
T S TA S+ S S + + + +PV++P E P S
Sbjct: 1604 VTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASP-EASTLSTTPVDSNSPV 1662
Query: 1286 LKERTVLSGSIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIK 1345
+ V S T ++ +G I + P+ + + P D T +
Sbjct: 1663 ITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVT 1722
Query: 1346 EMGRSIHEIPRQDILTQESRKTPE--------VVQSTRPIIEGS--------ISQGTPIK 1389
+ P T TP + ST P++ I TP+
Sbjct: 1723 TSTEA-RSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVT 1781
Query: 1390 FDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYEDVK---------- 1439
+ S S+ T S LS GM PL P + +V + +
Sbjct: 1782 TSTEATSSPTTAEGTSIPT--STLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPV 1839
Query: 1440 ------AGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRTP-------- 1485
+ + TS+ +S PS + L P + + + + TP
Sbjct: 1840 VTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVT 1899
Query: 1486 ----VSYQNTMSRGSPMMNRT-------------SDVTISSNK---------------ST 1513
VS T + GS M T S T++S++ +T
Sbjct: 1900 TYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTT 1959
Query: 1514 NHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMP 1573
+ S+ T S+P + G P+ S S A + + + T
Sbjct: 1960 YSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTS 2019
Query: 1574 FHRALDPAAAAYLF------QRQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNL 1627
+ P A + +P G P L ++ L+ + QV
Sbjct: 2020 TEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVV--SSEGNTLSTTPVDSKTQVTN 2077
Query: 1628 RPDVARGLSPREQPLGLPYPATRGIIDLTNMPPT---ILVPHPGGTSTPPMDRIT-YIPG 1683
+ + + + + P+ G LT++P + + P ST P+D + I
Sbjct: 2078 STEASSSATAEGSSMTISAPS-EGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITS 2136
Query: 1684 TQITFPPRPYNSASMSPGH-------------PTHLAAAASAEREREREREKERERERIA 1730
T+++ P P SM T + A+++ +
Sbjct: 2137 TEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNST 2196
Query: 1731 AASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPT 1790
A S G+ P S G S V T + + ++ TS TP+ +
Sbjct: 2197 EARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTS--TPVTTS 2254
Query: 1791 AQLRIMPLPAGGPSI-----SQGL-PASRYNTAADALAALVDAAASAPQMDVSKTKESKH 1844
+ P A G SI S+G P + + +A + S +D + +
Sbjct: 2255 TEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTST 2314
Query: 1845 EAARLEENLRSRS--AAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSE 1902
EA+ S + S + + V V TS+ + YS+
Sbjct: 2315 EASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQ 2374
Query: 1903 AGK-----DKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDS 1957
AG D P S Y E G T +T+ + + AS + + +
Sbjct: 2375 AGSSPTTADDTSMPTSTYSE-----GSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVT 2429
Query: 1958 SSSLSSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTR-QYEGPLHH 2016
+S+ +S T SP S P + VV + T P+
Sbjct: 2430 TSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTT 2489
Query: 2017 YRPQQESPSPQQQL--PPSSQAEGMGQV------------PRTHRLITL-ADHICQIITQ 2061
SP+ + + P S+ +EG + P L T D ++T
Sbjct: 2490 STEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTS 2549
Query: 2062 DFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTK 2096
+ +S PTST+ + L S PV TK
Sbjct: 2550 TEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTK 2584
Score = 53.5 bits (127), Expect = 2e-06
Identities = 195/919 (21%), Positives = 294/919 (31%), Gaps = 118/919 (12%)
Query: 687 SRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGN 746
S P + S + A S EAS+ E + + PSE S + N
Sbjct: 2759 STLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVN 2818
Query: 747 TEPAVELEP-TTETAPSTSPSLAVPSTK----PAEDESVETQVNDSISAET-AEQMDVDQ 800
P E T T P + + STK P E + ++ + T + V
Sbjct: 2819 HTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVST 2878
Query: 801 QEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDL 860
++ E S P + V E +S + T + SE P L
Sbjct: 2879 TPVASSEASTLSTTPVDTSIPVTTST---EGSSSPTTAEGT-SMPISTPSEVSTPLTSIL 2934
Query: 861 VVAQQINAQRPEPQS----DNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILV 916
V + S D + T SA+ P+ + P S+ V
Sbjct: 2935 VSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSV 2994
Query: 917 S---------SPLKPNPLD--LPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALYQRHIK 965
S S L P D P A P + IPI TP G
Sbjct: 2995 STMPVASSEASTLSRTPADTSTPVTTSTEASSSP-TTAEGTGIPISTPSEGSTPLTSIPV 3053
Query: 966 AMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWEVLQPAPHQVITNLPEGVRLP 1025
+ A+ E +D S SP TS + P P EG +P
Sbjct: 3054 STTPVAIPEASTLSTTPVD-----SNSPVVTSTEVSS-----SPTP-------AEGTSMP 3096
Query: 1026 TTRPTRPPPPL--IPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQE-----T 1078
+ + PL +P S T V S S + + TP T T + + T E T
Sbjct: 3097 ISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPT 3156
Query: 1079 PKPSVGSISLG--------LPRQQESAKSAT-----LPYIKQEEFSPRSQNSQPEGLLVR 1125
PS GS L + ++S SAT P E + S ++ +
Sbjct: 3157 STPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTE-ATSSTTAEGTSIPTS 3215
Query: 1126 AQHEGV-------VRGTAGAIQEGSITRGTPTSKISVESIPSLRGS--ITQGTPALPQTG 1176
EG+ V T A E SI TP V+S L S + P T
Sbjct: 3216 TPSEGMTPLTSVPVSNTPVASSEASILSTTP-----VDSNTPLTTSTEASSSPPTAEGTS 3270
Query: 1177 IPTEALVKGS--ISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRS 1234
+PT +GS ++ MP+ ++ S S + +Y + + S
Sbjct: 3271 MPTSTPSEGSTPLTSMPVSTTTVASSETSTLS---TTPADTSTPVTTYS------QASSS 3321
Query: 1235 PRTAHEISLKRSYESVEGNIKQGMSMRESP-VSAPLEGLICRALPRGSPHSDLKERTVLS 1293
P A S+ S S MS +P VS+ L + +P + E + LS
Sbjct: 3322 PPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEAS-LS 3380
Query: 1294 GSIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDG---ITTIKEMGRS 1350
+ +GT T S +G + + P+ + E P D +TT E S
Sbjct: 3381 PTTAEGT-SIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSS 3439
Query: 1351 --IHEIPRQDILTQESRKTPEVVQ--STRPIIEGS--------ISQGTPIKFDNNSGQSA 1398
I E T TP + ST P+ + TP+ + + S
Sbjct: 3440 PTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSP 3499
Query: 1399 IKHNVKSLITGPSKLSRGMPPLEIVPENIKVV---ERGKYEDVKAGETVRSRHTSVVSSG 1455
V S+ T S G PL +P + V E +S SS
Sbjct: 3500 TTAEVTSMPT--STAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSS 3557
Query: 1456 PSVLRSTLHEAPKAQLSPGIYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNH 1515
P+ L+ T T V+ + +P ++R++ VT T+
Sbjct: 3558 PATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVT------TST 3611
Query: 1516 ERKSTLTPTQRESIPAKSP 1534
+ ST TP + ++P +P
Sbjct: 3612 QSNSTPTPPEVITLPMSTP 3630
Score = 50.4 bits (119), Expect = 2e-05
Identities = 284/1444 (19%), Positives = 474/1444 (32%), Gaps = 280/1444 (19%)
Query: 1019 PEGVRLPTTRPTRPPPPL--IPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQ 1076
PE +P + + PL +P+S VAS + ++ + TP T + + T
Sbjct: 201 PESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTA 260
Query: 1077 ETPK-----PSVGS-------ISLGLPRQQESAKSAT------LPYIKQEEFSPRSQNSQ 1118
E P PS GS +S+ L E++ +T +P I E S ++
Sbjct: 261 EGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAE 320
Query: 1119 PEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ---- 1174
+ EG T+ T TS++S SI + S T P
Sbjct: 321 GTSIPTSTYTEGSTPLTSTPAS----TMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPT 376
Query: 1175 ----TGIPTEALVKGS--ISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNA 1228
T + T L +GS ++ MP+ S+ EA++ + + K+ + A
Sbjct: 377 TAEATSMLTSTLSEGSTPLTNMPV--STILVASSEASTTSTIPVDSKTF-------VTTA 427
Query: 1229 REGTRSPRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKE 1288
E + SP TA + S+ S S M + +PV++ E
Sbjct: 428 SEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVAS-------------------SE 468
Query: 1289 RTVLSGSIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMG 1348
+ LS + + + TT + + S P A ++ P +G T + M
Sbjct: 469 ASNLSTTPVDSKTQVTTST-----------EASSSPPTAEVNSMPTSTPSEGSTPLTSMS 517
Query: 1349 RSIHEIPRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLIT 1408
S + + T ST P+ TP+ + + S+ S+ T
Sbjct: 518 VSTMPVASSEASTL----------STTPV-----DTSTPVTTSSEASSSSTTPEGTSIPT 562
Query: 1409 GPSKLSRGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPK 1468
S S G PL +P + ++V S S S+ P+ + + + +
Sbjct: 563 --STPSEGSTPLTNMPVSTRLVV--------------SSEASTTSTTPADSNTFVTTSSE 606
Query: 1469 AQLSPGIYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRES 1528
A S T+A T + RG+ + + + T+ ++ STL+ T
Sbjct: 607 ASSS-----STTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEA-----STLSTT---- 652
Query: 1529 IPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPF-HRALDPAAAAYLF 1587
PV PV + + ST E T+ + + P ++ A
Sbjct: 653 -----PVDSNTPVTTSTEATS---SSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSE 704
Query: 1588 QRQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYP 1647
LS TP + + + + P A G S P P
Sbjct: 705 ASTLSTTP-----------------VDTSTPVTTSTEASSSPTTADGAS---MPTSTP-- 742
Query: 1648 ATRGIIDLTNMP--PTILVPHPGGT-STPPMDRITYIP-GTQITFPPRPYNSASMSPGHP 1703
+ G LT+MP T+L T ST P+D T+I T+ + P SM P
Sbjct: 743 -SEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTP 801
Query: 1704 THLAAAASAEREREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRT 1763
+ S L P S P V SP S +
Sbjct: 802 SE--------------------------GSPLLTSIPVSITP--------VTSPEASTLS 827
Query: 1764 QETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAA 1823
T +P+ + ++ P PA G S +P S Y+ L +
Sbjct: 828 --------------TTPVDSNSPVTTSTEVSSSPTPAEGTS----MPTSTYSEGRTPLTS 869
Query: 1824 LVDAAASAPQMDVSKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYT 1883
M VS T + + L S V T E RS
Sbjct: 870 ----------MPVSTTLVATSAISTLSTTPVDTSTPV---------TNSTEARSSPTTSE 910
Query: 1884 SSAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIAS 1943
++ P+ P S+ + S D P S E RT T + + V + + S
Sbjct: 911 GTSMPTSTPGEGSTPLTSMP--DSTTPVVS---SEARTLSATPVDTST--PVTTSTEATS 963
Query: 1944 DKDARERGSQSSDSSSSLSSHRYETP-SDAIEVISPASSPAPPQEKLQTYQPEVVKANQA 2002
E S + + S ++ TP S + S AS+ + T P +
Sbjct: 964 SPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNT--PLTTSTEAS 1021
Query: 2003 ENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQD 2062
PT EG E +P ++P S+ + T AD + T
Sbjct: 1022 SPPPTA--EGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLST--TPADTSTPVTTYS 1077
Query: 2063 FARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPE 2122
A + ++ PTST+ + L S PV S R S+A ++ S +
Sbjct: 1078 QASSSSTTADGTSMPTSTYSEGSTPLTSVPV----STRLVVSSEASTL------STTPVD 1127
Query: 2123 NLVDKSRGSRPGKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDA 2182
+ + + SP + +S P P S P+ + L++S + D+
Sbjct: 1128 TSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDS 1187
Query: 2183 RSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVT 2242
++ + S S + M S E L S + +A+++ T + V
Sbjct: 1188 KTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEAST--LSTSPVD 1245
Query: 2243 TSGSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVV 2302
TS V++ + + P + G S G + + V +T++V
Sbjct: 1246 TSTPVTTSAETSSSPTTAEGT----------SLPTSTTSEGSTLLTSIPV-----STTLV 1290
Query: 2303 TSGETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERP------------ 2350
TS E P G V +S S + + +P Y P
Sbjct: 1291 TSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVA 1350
Query: 2351 SSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPT--PIACAPSAV 2408
SS S+ S TP + SS +++ P + +TP T P++ P
Sbjct: 1351 SSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVS 1410
Query: 2409 NQAA 2412
++A+
Sbjct: 1411 SEAS 1414
Score = 49.3 bits (116), Expect = 5e-05
Identities = 181/917 (19%), Positives = 308/917 (33%), Gaps = 112/917 (12%)
Query: 701 SVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPEN--ATSRGNTEPAVELEPTTE 758
S + T + I +E P S + + P S + +T+ +T V
Sbjct: 2907 SSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEAS 2966
Query: 759 TAPSTSPSLAVPSTKPAEDE------SVETQVNDSISAETAEQMDVDQQEHSAEEGSVCD 812
++P+T+ ++P + P E SV T S A T + D
Sbjct: 2967 SSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASS 3026
Query: 813 PPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPE 872
P T A+ + + P EG +T + ++ V + + +++ P
Sbjct: 3027 SP--TTAEGTGIPISTPS------EG-STPLTSIPVSTTPVAIPEASTLSTTPVDSNSPV 3077
Query: 873 PQSDNDSSATCSAD-EDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDL--PQ 929
S SS+ A+ + + P+ P P S +S+ L P+D P
Sbjct: 3078 VTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAIST-LSTTPVDTSTPV 3136
Query: 930 LQHRAAVIPPMVSCTPCNIPIGTPVSG-----YALYQRHIKAMHESALLEE---QRQRQE 981
A P S ++P TP G Y + E + L
Sbjct: 3137 TTSTEAHSSPTTS-EGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPV 3195
Query: 982 QIDLECRSSTSPCGTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPL--IPS 1039
E SST+ GTS +PT+ P+ PL +P
Sbjct: 3196 TTSTEATSSTTAEGTS--------------------------IPTSTPSEGMTPLTSVPV 3229
Query: 1040 SKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQE-----TPKPSVGSISL-GLP-- 1091
S T VAS + S + + TP T T + + T E T PS GS L +P
Sbjct: 3230 SNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVS 3289
Query: 1092 -RQQESAKSATLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPT 1150
S++++TL + +P + SQ A + T EGS TP
Sbjct: 3290 TTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTST---YSEGS----TPL 3342
Query: 1151 SKISVESIP--SLRGSITQGTPALPQTGIPTE---ALVKGSISRMPIEDSSPEKGREEAA 1205
+ +S + P S S TP T + T +L + I SSP +G A
Sbjct: 3343 TNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLA 3402
Query: 1206 SKGHVIYEGKSGHILSYDN--------IKNAREGTRSPRTAHEISLKRSYESVEGNIKQG 1257
S S + + + + E + SP A SL S S
Sbjct: 3403 SMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSI 3462
Query: 1258 MSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYPKQ 1317
M + +PV++ + S T S + + T T+ + E G
Sbjct: 3463 MPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGE-GSTPLTN 3521
Query: 1318 IKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPI 1377
+ + P+ + E + P D T + ++ + T E S +
Sbjct: 3522 MPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTM 3581
Query: 1378 I---------------EGSISQGTPIKFDNNSGQSAIKHNVKSL-ITGPSKLSRGMPPLE 1421
+ S+ + TP+ S + V +L ++ PS++S + +
Sbjct: 3582 LLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMP 3641
Query: 1422 IVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHE--APKAQLSPGIYDDT 1479
+ ++ + E G + + ++ VSS P T P +P
Sbjct: 3642 VSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPV 3701
Query: 1480 SARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTL-TPTQRESIPAKSPVPGV 1538
S R S +T+S +P + ++ VT S+ ++ +TL + T S+P + G
Sbjct: 3702 STTRVTSSEGSTLS--TPSVVTSTPVTTSTEAISS---SATLDSTTMSVSMPMEISTLGT 3756
Query: 1539 DPVVSHSPFDPHHRGST 1555
+VS +P ST
Sbjct: 3757 TILVSTTPVTRFPESST 3773
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 69.7 bits (169), Expect = 3e-11
Identities = 131/770 (17%), Positives = 306/770 (39%), Gaps = 97/770 (12%)
Query: 178 KEELIQSMDRVD--REIAKVEQQILKLKKKQQ---QLEEEAAKPPEPEKPVSPPPVEQKH 232
+EE ++ ++R + RE + EQQ +L+++QQ + EEE + E + +Q+
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
Query: 233 RSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILF 292
R Q+ ++ ++ ++ + E + +L + + + + ++ Q +R++ L
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERREQQL---RREQEEERREQQLRREQQLRREQQL- 389
Query: 293 FKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQ 352
+R R++++ + Q+ + + ++ R E RR+ +E + + +E++ E R +
Sbjct: 390 -RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448
Query: 353 REQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQ 412
REQ+ER + + E E EQE ++Q+++ E+
Sbjct: 449 REQEERRDWL------------KREEETER-----HEQERRKQQLKR--------DQEEE 483
Query: 413 RRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVP 472
RR +++ + E+ + ++R+ + + E+ +++ ++ + + L +
Sbjct: 484 RRERWLKLE---EEERREQQERREQQLRREQEER--REQRLKRQEEEERLQQRLRSEQ-- 536
Query: 473 DCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEK 532
L ++ E RR +R +++ + +E++++ ++E++ ++ K+EEE+
Sbjct: 537 ------QLRREQEE-----RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
Query: 533 KDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGR----------KTANSQGRRK 582
+ + K E+E+ E ++++++ E+ E REQ R K+ + RR+
Sbjct: 586 RQQRLKREQEERLEQRLKREEVE-RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Query: 583 GRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVE 642
++ R EE L + E EEE E A++ +
Sbjct: 645 QQLRREQQER-----REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Query: 643 HGRNW---------AAIAKMVG--TKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPR 691
W A +K+ K E Q + KRR L Q +++ R+ +
Sbjct: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ 759
Query: 692 EE---RDVS-------QCESVASTVSAQED--EDIEASNEEENPEDSEVEAVKPSEDSPE 739
EE RD + + E +SA+ E E E + E + E+ +
Sbjct: 760 EEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQ 819
Query: 740 NATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVD 799
R E ++ E + + + E E + + + + ++
Sbjct: 820 RRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLE 879
Query: 800 QQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLD---RASEKVEPR 856
++ P + ++ E + E + + ++ + R E+++
Sbjct: 880 EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQE 939
Query: 857 DEDLVVAQQINAQRP--EPQSDNDSSATCSADEDVDGEPERQRMFPMDSK 904
+E L+ ++ +R E Q D ++ + EPE++R + K
Sbjct: 940 EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989
Score = 68.2 bits (165), Expect = 1e-10
Identities = 130/748 (17%), Positives = 287/748 (38%), Gaps = 82/748 (10%)
Query: 175 KLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRS 234
KL +EE + +R ++++ + +++ + + K+Q+ EE + E+ + E++
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE-- 547
Query: 235 IVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFK 294
Q++ E K+ E+ + + +K Q R+ +L K
Sbjct: 548 --QLLKREEEKRLEQERR-----------------------EQRLKREQEERRDQLL--K 580
Query: 295 RRNHARKQR-----EQKICQRYD-QLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPE 348
R R+QR E+++ QR + +E E++ R + R + +E + ++ + + E
Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQE 640
Query: 349 IRKQ----REQQERFQRVGQRGAGLSATIAR--SEHEISEIIDGLSEQENNEKQMRQLSV 402
R+Q REQQER ++ +R R EHE L+E+E + + R S
Sbjct: 641 ERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSR 700
Query: 403 IPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLI 462
IP + E + + P K R+ EK ++ +Q +
Sbjct: 701 IPKWQWQLESE--ADARQSKVYSRPRKQEGQRRRQE---QEEKRRRRESELQWQEEERAH 755
Query: 463 ASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQI---ARPSQEEKVEEKEE 519
E + D + +K+E + + R R +Q+ R +E++ +EE
Sbjct: 756 RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEE 815
Query: 520 DKAEKTEKKEEEKK-----DEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKT 574
+K ++ ++ E +K +EEE+ ++ + + +E++ DG E+ E R R
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE--DGLQEDQERRRSQEQR---- 869
Query: 575 ANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEME 634
+ + R + R A A + L E + E E R E+E +
Sbjct: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
Query: 635 VAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREER 694
++ ++ + + + + + + + K + + LL + +K R+ RE++
Sbjct: 930 YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989
Query: 695 DVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELE 754
+ E + +E++ + E+ ++ E + K E E E + E
Sbjct: 990 YREEEE-----LQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE-------EQLLREE 1037
Query: 755 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPP 814
E+E + + ++ + E+ ++E EE +
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 815 PATKADS-------VDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQIN 867
P + + E++ E + E + + ++L+R + E ++ +Q+
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE---EEQLL 1154
Query: 868 AQRPEPQSDNDSSATCSADEDVDGEPER 895
+ PE + + +E++ E E+
Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQ 1182
Score = 65.9 bits (159), Expect = 5e-10
Identities = 85/416 (20%), Positives = 181/416 (43%), Gaps = 39/416 (9%)
Query: 175 KLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAA-------KPPEPEKPVSPPP 227
K +EE S DR+ + EQQ+ + +++++ LEEE K E E+ +
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Query: 228 VEQKHRSIV--QIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVM 285
+Q HR + + +E + + +E + F + + P + + H + + +
Sbjct: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534
Query: 286 RKKLILFFKRRNHARKQ-REQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTR-EYYE 343
+++ L + R R+Q R++K + E E+++ R E + + + +E K R + E
Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 344 KQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQE-----------N 392
++F E +Q +QE Q++ Q R E +++ EQ+
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERD-------RKFREDEQLLQEREEQQLHRQERDRKFLE 1647
Query: 393 NEKQMRQLSVIPPMMFDAEQ--RRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKD 450
E Q+R+ + D ++ R + + G + + +DR+F ++ +
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Query: 451 KFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQ 510
KF+Q + L LERK + L + E + +RR R+ ++ RP +
Sbjct: 1708 KFLQEEQQ--LRRQELERKFREEEQL------RQETEQEQLRRQERYRKILEEEQLRPER 1759
Query: 511 EEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQ 566
EE+ ++E + E+++ ++ EE++ ++S +E++++ EE + R Q
Sbjct: 1760 EEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQ 1815
Score = 64.7 bits (156), Expect = 1e-09
Identities = 80/435 (18%), Positives = 190/435 (43%), Gaps = 47/435 (10%)
Query: 178 KEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQ-KHRSIV 236
K+E ++ DR R+ Q+ ++++++ EEE + + + P EQ + R ++
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
Query: 237 QIIY----DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILF 292
++ ++ +++ E ++F+ + E + + + E ++ + R++ +
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQ---EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ- 272
Query: 293 FKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQ 352
+ RK Q++ R ++ E +++ R E RRK +E + + E++ + R++
Sbjct: 273 -EEEEQLRKLERQEL--RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329
Query: 353 REQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQ 412
++++ R Q++ + R E E L ++ E++ +QL + + +
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 413 RRVKFINMNGLMEDPMKVYKDRQF---------MNVWTDHEKEIFKDKFIQHPKNFGLIA 463
RR + + + ++ +++Q + + E+E + K Q + L
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Query: 464 SYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEE----KEE 519
ER+ +L ++ E + R R QQ+ R +EE+ E +EE
Sbjct: 450 EQEERRD--------WLKREEETERHEQER-------RKQQLKRDQEEERRERWLKLEEE 494
Query: 520 DKAEKTEKKE-------EEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGR 572
++ E+ E++E EE++++ K ++E+ + + + + E+ E REQ R
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Query: 573 KTANSQGRRKGRITR 587
+ Q RR+ R+ R
Sbjct: 555 EKRLEQERREQRLKR 569
Score = 63.5 bits (153), Expect = 2e-09
Identities = 90/474 (18%), Positives = 196/474 (41%), Gaps = 74/474 (15%)
Query: 176 LSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSI 235
L +E+ ++ +R +R+ K EQQ+ +++QQ ++ K E E+ +S ++K R
Sbjct: 1377 LEEEQRLRRQER-ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREE 1435
Query: 236 VQII---------YDENRKKAEEAHKIF----EGLGPKVELPLYNQPSDTKVYHENIKTN 282
Q + +E ++ +E H+ F + L + E L+ Q D K E
Sbjct: 1436 EQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEE---Q 1492
Query: 283 QVMRKKLILFFKRRNHARKQREQKICQRYDQL-MEAWEKKVDRIENNPRRKAKESKTREY 341
Q+ R++ F+ + ++ E+K + QL + ++K + E RR+ + + R+
Sbjct: 1493 QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Query: 342 YEKQFPE---IRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQ 396
+++F E +R++RE+Q+ ++ R L R + + + ++ + ++ ++Q
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Query: 397 MRQ------------LSVIPPMMFDAEQRRVKFIN------------------------- 419
+RQ L ++R KF+
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 420 ----MNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 475
G + + +DR+F ++ + KF+Q + L LERK +
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQ--LRRQELERKFREEEQ 1730
Query: 476 LYYYL----TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEK---- 527
L ++ E Y+ ++ + QQ+ R ++ K E+E+ + E+ E+
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRS 1790
Query: 528 KEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRR 581
+E ++K EE+ +++ +E + DG EE+ Q + ++ + R+
Sbjct: 1791 QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ 1844
Score = 61.2 bits (147), Expect = 1e-08
Identities = 131/769 (17%), Positives = 297/769 (38%), Gaps = 96/769 (12%)
Query: 167 DDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLE-------EEAAKPPEP 219
+ Q +L +E+ ++ +R K EQ+ + + K++Q E EE + E
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469
Query: 220 EK---PVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYH 276
E+ + E++ +++ +E R++ E + + + + +
Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529
Query: 277 ENIKTNQVMRKKLILFFKRRNHARKQREQKICQ---RYDQLMEAWEKKVDRIENNPRRKA 333
+ +++ Q +R++ +RR K+ E+K + R +L E++ D++ +
Sbjct: 530 QRLRSEQQLRREQE---ERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Query: 334 KESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENN 393
++ RE E+ E R +RE+ ER ++ +R L E +++ ++E
Sbjct: 587 QQRLKREQEERL--EQRLKREEVERLEQEERREQRLKREEPEEERR-QQLLKSEEQEERR 643
Query: 394 EKQMRQLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFI 453
++Q+R+ + ++R+K +E +K +HE+E + +
Sbjct: 644 QQQLRREQQ------ERREQRLKREEEEERLEQRLK-----------REHEEERREQELA 686
Query: 454 QHPKNFGLIASYLERKSVP--DCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQE 511
+ + A + +P L + + R+ G+RR + Q+ R +E
Sbjct: 687 EEEQEQ---ARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743
Query: 512 EKVEEKEEDKAEKTEKKEEEKKD------EEEKDEKE----DSKENTKEKDKIDGTAEET 561
+++ +EE++A + +++EE+++D EEK E+ ++ +E+ + AEE
Sbjct: 744 SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER 803
Query: 562 EEREQ---ATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPE-P 617
++REQ ++ Q R + + + + E A +E L E
Sbjct: 804 QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERR 863
Query: 618 ISTEPVETSRW---TEEEME------VAKKGLVEHGRNWAAI--AKMVGTKSEAQCKNFY 666
S E +W EEE + AK L E R + + + E + K
Sbjct: 864 RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923
Query: 667 FNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDS 726
+R++ + LQQ +++ R+ RE+R QE E +++ ++
Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKR------------RRQERERQYRKDKKLQQKEE 971
Query: 727 EVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVND 786
++ +P + + + E ++ E + + Q +
Sbjct: 972 QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031
Query: 787 SISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDL 846
+ E E+ + ++E E + E++ E E + + ++L
Sbjct: 1032 QLLREEREKRRLQERERQYRE---------------EEELQQEEEQLLGEERETRRRQEL 1076
Query: 847 DRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPER 895
+R K E ++ +Q+ + PE + + C +E++ E E+
Sbjct: 1077 ERQYRKEEELQQE---EEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122
Score = 58.2 bits (139), Expect = 1e-07
Identities = 123/660 (18%), Positives = 263/660 (39%), Gaps = 58/660 (8%)
Query: 44 RSSHLEVSQASQLLQQQQQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDS 103
R E + Q L++++Q Q R R L E G QERR S E
Sbjct: 821 RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE------------Q 868
Query: 104 LESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQ 163
++ R + + +R + P L E LR ++ + E +
Sbjct: 869 RRDQKWRWQLEEERKRRRHTLYAKPA---LQEQLRKEQQLLQEEEEELQREEREKRRRQE 925
Query: 164 PCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPV 223
+ + +E+L++ +R R + E+Q K KK QQ+ E+ + PE +
Sbjct: 926 QERQYREEEQLQQEEEQLLRE-EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ 984
Query: 224 SPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQ 283
E+K+R ++ +E + EE K + Y + + + E + +
Sbjct: 985 ER---EKKYREEEELQQEEEQLLREEREKRRRQEWERQ----YRKKDELQQEEEQLLREE 1037
Query: 284 VMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYE 343
+++L + R+ RE++ Q+ ++ + E++ R + R+ KE + ++ E
Sbjct: 1038 REKRRL------QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE 1091
Query: 344 ---KQFPEIRK--QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMR 398
++ PE R+ +RE+Q R + Q+ R + E+ E+E +++
Sbjct: 1092 QLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEE 1151
Query: 399 QLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKN 458
QL P ++ ++ L ++ ++ ++ Q + E++ +++ +Q K
Sbjct: 1152 QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRR-QERERQYREEEELQRQKR 1210
Query: 459 FGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKE 518
Y + D + K+N VR N +GR + R ++ ++ +++
Sbjct: 1211 K---QRYRDEDQRSDLKWQWEPEKENA-----VRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
Query: 519 EDKAEKTEKKEEEKKD-EEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANS 577
+ + E++++D E+E+ + + E++++ E EE+++A R RK+
Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQL-----EREEQKEAKRRDRKS--- 1314
Query: 578 QGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEM---E 634
+ + ++ R E EE +P+ + ++ EEE+ E
Sbjct: 1315 --QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE-RDRKFREEELRHQE 1371
Query: 635 VAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREER 694
+K L E R + K E Q + + R + D ++ +Q+ SR+ R+ +
Sbjct: 1372 QGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRK 1431
Score = 54.7 bits (130), Expect = 1e-06
Identities = 98/554 (17%), Positives = 230/554 (41%), Gaps = 58/554 (10%)
Query: 33 RHQQEFAVPDYRSSHLEVSQASQLLQQQQQQQLRRRPSLLSEFHPGSDRPQERRTSYEPF 92
R Q++ R S L+ + + +QQQ+++ RR + + S+R ++R ++ P
Sbjct: 731 RRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL 790
Query: 93 HPGPSPVDHDSLESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGLRASADAKKDPAFGGK 152
+ R Q+ Q+ LP + R + +K+ F +
Sbjct: 791 --------------REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
Query: 153 HEAPSSPISGQPCGDD----QNASPSKLSKEELIQSMDR--VDREIAKVEQQILKLKKKQ 206
E Q ++ Q + S+E+ R ++ E + + Q
Sbjct: 837 EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ 896
Query: 207 QQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLY 266
+QL +E E E+ + E++ R + Y E + +E ++ + E
Sbjct: 897 EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL-----REEREKR 951
Query: 267 NQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIE 326
+ + Y ++ K Q +++ +L + R++RE+K + E+++ + E
Sbjct: 952 RRQERERQYRKDKKLQQ--KEEQLLGEEPEKRRRQEREKKYRE---------EEELQQEE 1000
Query: 327 NNPRRKAKESKTREYYEKQF---PEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEI 383
R+ +E + R+ +E+Q+ E++++ EQ R +R +R R E E+ +
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQY-REEEELQQE 1059
Query: 384 IDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDH 443
+ L +E ++ ++L + +Q + L E+P K + RQ +
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQL-----LREEPEK--RRRQ------ER 1106
Query: 444 EKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQ 503
E++ +++ +Q + L+ E++ + Y ++ + + + R ++R R +
Sbjct: 1107 ERQCREEEELQQEEE-QLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165
Query: 504 QIARPSQEEKVEEKEE----DKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAE 559
+ +EE+++++EE ++ EK ++ E + EEE+ +++ K+ +++D+
Sbjct: 1166 LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
Query: 560 ETEEREQATPRGRK 573
+ E ++ R K
Sbjct: 1226 QWEPEKENAVRDNK 1239
Score = 54.3 bits (129), Expect = 1e-06
Identities = 107/572 (18%), Positives = 226/572 (39%), Gaps = 112/572 (19%)
Query: 47 HLEVSQASQLLQQQQQQQLRRRP---SLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDS 103
H + + QLLQ++++QQL R+ L E + ++R+ + S
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR---------S 1510
Query: 104 LESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQ 163
E +R LE+ H Q+ L L R GQ
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER-----------------------GQ 1547
Query: 164 PCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQ-QLEEEAAKPPEPEKP 222
D++ K +EE + R +RE EQQ+ + ++ ++ +LEE+ + E E+
Sbjct: 1548 QRRQDRDR---KFREEEQL----RQERE----EQQLSRQERDRKFRLEEQKVRRQEQERK 1596
Query: 223 VSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTN 282
+ + + Q + E +K E ++ + + E L+ Q D K E
Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ---EREEQQLHRQERDRKFLEEE---P 1650
Query: 283 QVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPR-RKAKESKTREY 341
Q+ R++ R R R++K + L E E+++ R E + + R+ ++ R+
Sbjct: 1651 QLRRQE------REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE 1704
Query: 342 YEKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLS 401
E++F Q EQQ R Q + ++ R E ++ + +EQE +Q R
Sbjct: 1705 RERKF----LQEEQQLRRQELERK--------FREEEQLRQE----TEQEQLRRQERYRK 1748
Query: 402 VIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGL 461
++ E+ + +DR+F E+++ +++ Q ++
Sbjct: 1749 ILEEEQLRPEREEQQLRRQE----------RDRKFRE-----EEQLRQEREEQQLRSQES 1793
Query: 462 IASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEK---- 517
+ E + L ++ E + ++ GK R +Q+ QE+++ ++
Sbjct: 1794 DRKFREEEQ---------LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ 1844
Query: 518 ----EEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRK 573
E+ ++ ++EE++ +EE+ ++ +E ++ I +E + Q +
Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQV----GE 1900
Query: 574 TANSQGRRKGRITRSMTNEAAAASAAAAAATE 605
+ +G+ GR+ T++ A+ ++ E
Sbjct: 1901 IKSQEGKGHGRLLEPGTHQFASVPVRSSPLYE 1932
Score = 51.6 bits (122), Expect = 9e-06
Identities = 77/435 (17%), Positives = 170/435 (39%), Gaps = 49/435 (11%)
Query: 178 KEELIQSMDRVDREIAKVEQQILKL---KKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRS 234
+ + ++ R + E+ + E+Q+L+ K+++Q+LE + + E ++Q+
Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE---------LQQEEEQ 1182
Query: 235 IVQIIYDENRKKAEEAHKIFEGLGPKVELPLY---NQPSDTKVYHENIKTNQVMRKKLIL 291
+++ ++ R++ E ++ E L + Y +Q SD K E K N V K+
Sbjct: 1183 LLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYC 1242
Query: 292 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQ--FPEI 349
+ R+ + ++ R Q + + + + + +E + R + ++ FPE
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQ------QDLQHLLGEQQERDREQERRRWQQRDRHFPEE 1296
Query: 350 RKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFD 409
+ ++++ + R + + R E E + E+Q+ Q P+
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356
Query: 410 AEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERK 469
R+ + E+ + R+F+ ++ + KF++ + + +
Sbjct: 1357 ERDRKFR-------EEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR 1409
Query: 470 SVPDCVLYYYLTKKNENYKALVRRNYGKR-RGRNQQIARPSQEEKVEEKEEDKAEKTEKK 528
D K E + L R+ ++ R QQ+ R +E K E+E+ ++ +K
Sbjct: 1410 QDRD-------RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK 1462
Query: 529 -----------EEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANS 577
EE++ +E+D K +E + + D E E R Q R
Sbjct: 1463 FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQ 1522
Query: 578 QGRRKGRITRSMTNE 592
Q R+ R + + E
Sbjct: 1523 QLHRQQRQRKFLQEE 1537
Score = 48.9 bits (115), Expect = 6e-05
Identities = 127/720 (17%), Positives = 268/720 (37%), Gaps = 111/720 (15%)
Query: 174 SKLSKEELIQSMDRVDREIAKVE-QQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKH 232
S+ + L+ DRE + QQ + +++QLE E K + S Q+
Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKS-----QEE 1317
Query: 233 RSIVQIIYDENRKKAEEAHKIFEG---LGPKVELPLYNQPSDTKVYHENIKTNQVMRKKL 289
+ +++ +E R++ E K E L + E PL Q D K E ++ + RK
Sbjct: 1318 KQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK-- 1375
Query: 290 ILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPR--RKAKESKTREYYEKQFP 347
F + R+Q ++ + +Q + E++ ++ R R+ ++ +R+ +++F
Sbjct: 1376 --FLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR 1433
Query: 348 EIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMM 407
E +Q +QER ++ + L R E +++ QE E+Q+ +
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLL-----QEREEQQLHR-------- 1480
Query: 408 FDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLE 467
++R KF+ + + +DR+F E+E+ Q P E
Sbjct: 1481 ---QERDRKFLEEEQQLR---RQERDRKF------REQELRS----QEP----------E 1514
Query: 468 RKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEK 527
RK +L ++ + ++ +R + + +E+++ +E + + ++
Sbjct: 1515 RK---------FLEEEQQLHRQQRQRKFLQ------------EEQQLRRQERGQQRRQDR 1553
Query: 528 KEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEE------------TEEREQATPRGRKTA 575
+ +++E+ + E+E+ + + +E+D+ E+ +E++ G++
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Query: 576 NSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEV 635
+ RK R + E E L P+ E + R +
Sbjct: 1614 RQERDRKFREDEQLLQE---REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR 1670
Query: 636 AKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERD 695
++ L++ G + K + + + R L Q +Q+ RK REE
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
Query: 696 VSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEP 755
+ Q E+ + QE E+ PE E + + D + E +
Sbjct: 1731 LRQ-ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLR 1789
Query: 756 TTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPP 815
+ E+ + + E++ + Q D EQ+ +++QE +
Sbjct: 1790 SQESDRKFREEEQLRQER--EEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ-------- 1839
Query: 816 ATKADSVDVEVRVPENHAS-----KVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQR 870
D + R E A+ + E + +E + R E+ E+ + QQ QR
Sbjct: 1840 -----ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
Score = 43.5 bits (101), Expect = 0.003
Identities = 68/405 (16%), Positives = 157/405 (38%), Gaps = 29/405 (7%)
Query: 334 KESKTREYYEKQFPEIRKQREQQERFQ---RVGQRGAGLSATIARSEHEISEIIDGLSEQ 390
+E + R ++ + R+Q E Q RF+ R + G R E E E+ +G +
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQE-RELAEGEEQS 155
Query: 391 ENNEKQMRQLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKD 450
E E+ ++ D ++R + ++ + + + + HE E F D
Sbjct: 156 EKQERLEQR---------DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD 206
Query: 451 ------KFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQ 504
+ + + G +R+ D V K+ + ++R+ K + Q
Sbjct: 207 EEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQ 266
Query: 505 IARPSQEEKVEEKEEDKAEKTEKKEEEKKDEE--EKDEKEDSKENTKEKDKIDGTAEETE 562
R QEE+ + ++ ++ E +++EE++ ++ ++++ K+ + +++ + E+ E
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 563 EREQATPRGRK--TANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPIST 620
REQ R + + RR+ ++ R E E L +
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 621 EPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQ 680
+ + + E ++ ++ + R + + + E Q + + RH + +
Sbjct: 387 QQLRREQQLRREQQLRRE---QQLRREQQLRREQQLRREQQLRR--EQEEERHEQKHEQE 441
Query: 681 QHKQKTSRKPREERD-VSQCESVASTVSAQEDEDIEASNEEENPE 724
+ +Q+ R+ E RD + + E + + ++ EEE E
Sbjct: 442 RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
Score = 42.7 bits (99), Expect = 0.004
Identities = 83/438 (18%), Positives = 180/438 (41%), Gaps = 47/438 (10%)
Query: 178 KEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQ 237
+EE + +R R ++E+Q K ++ QQ EEE EPEK ++ + +
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQ--EEEQLLREEPEK--------RRRQERER 1108
Query: 238 IIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRN 297
+E + EE + E + L Q Y E + Q + L R
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQELERQ------YREEEEVQQEEEQLL------RE 1156
Query: 298 HARKQREQKICQRY--DQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQ 355
K+R Q++ ++Y ++ ++ E+++ R E RR+ +E + RE E Q + RKQR +
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK-RKQRYR 1215
Query: 356 QE------RFQRVGQRGAGLSATIA----RSEHEISEIIDGLSEQENNEKQMRQLSVIPP 405
E ++Q ++ + R + ++ D +++ ++ L +
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHL-LGEQ 1274
Query: 406 MMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDH----EKEIFKDKFIQHPKNFGL 461
D EQ R ++ + + ++ ++ Q D EK++ +++ + +
Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
Query: 462 IASYLERKSVPDCVLYYYLTKKNENYK----ALVRRNYGKRRGRNQQIARPSQEEKVEEK 517
+ E + + L ++ + K L + G++ +Q R + E+ K
Sbjct: 1335 DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLK 1394
Query: 518 EEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEE---TEEREQATPRGRKT 574
EE + E++++ ++D + K +E+ + + +E+D+ E+ +ERE+ +
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
Query: 575 ANSQGRRKGRITRSMTNE 592
+ RK R + E
Sbjct: 1455 LRQERHRKFREEEQLLQE 1472
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 68.2 bits (165), Expect = 1e-10
Identities = 150/730 (20%), Positives = 269/730 (36%), Gaps = 115/730 (15%)
Query: 180 ELIQSMDRVDREIAKV-------EQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKH 232
EL +++ V+ E A+V E+ I +LK++ EEEA + E + + +
Sbjct: 156 ELRATLEMVNHEKAQVQLDSDHLEEDIHRLKER---FEEEARLRDDTEAAIRALRKDIEE 212
Query: 233 RSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILF 292
S+V++ D KK + L E + + + + H ++ ++ +
Sbjct: 213 ASLVKVELD---KKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTA 269
Query: 293 FKR-RNHARKQREQKICQ-------RYDQLMEAWEKKVDRIENNPRRKAKE--SKTREYY 342
K R+ +Q + Q RY +L EA E+ + I R AKE ++ R
Sbjct: 270 LKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAI-----RSAKEEIAEYRRQL 324
Query: 343 EKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENN--------E 394
+ + E+ R +E +R LS R H++S D + + EN
Sbjct: 325 QSKSIELESVRGTKESLERQ------LSDIEERHNHDLSSYQDTIQQLENELRGTKWEMA 378
Query: 395 KQMRQLSVI--PPMMFDAE---------QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDH 443
+ +R+ + M D E +F G + P+ ++ ++
Sbjct: 379 RHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQK 438
Query: 444 EKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKAL--------VRRNY 495
K +QH + +E V D +K+E +AL V
Sbjct: 439 PKVEAPKLKVQHK----FVEEIIEETKVED--------EKSEMEEALTAITEELAVSMKE 486
Query: 496 GKRRGRNQQIARPSQEEK------------VEEKEEDKAEKTEKKEEEKKDEEEKDEKED 543
K+ ++ P EE+ E +E++ EK E++ +E+++EE++ K D
Sbjct: 487 EKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSD 546
Query: 544 SKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAA 603
E + + EE E+ E T + ++ + + ++ A A A
Sbjct: 547 QAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAK 606
Query: 604 TEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCK 663
E+P P P+ PVE E+ K VE V K ++
Sbjct: 607 VEKPEKAKSPVPK----SPVE-----EKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 657
Query: 664 NFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENP 723
K + + + K K+ P + V + +S A ++ E+ E+E
Sbjct: 658 KSPVEEKGKSPVSKSPVEEKAKS---PVPKSPVEEAKSKAEVGKGEQKEE----EEKEVK 710
Query: 724 EDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQ 783
E + E V+ E+ P++ + E V+ E E T S+ V K ++E Q
Sbjct: 711 EAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK-SVKVHLEKETKEEGKPLQ 769
Query: 784 VNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKAD-SVDVEVRVPENHASKVEGDNTK 842
+ E+ + S EEGS + K D +V+ EV E +VE TK
Sbjct: 770 -------QEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKE----EVE-QETK 817
Query: 843 ERDLDRASEK 852
E+ R EK
Sbjct: 818 EKGSGREEEK 827
Score = 36.2 bits (82), Expect = 0.41
Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 13/133 (9%)
Query: 467 ERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARP---SQEEKV----EEKEE 519
E K V + + KK E K + + + + + +A ++ KV E KEE
Sbjct: 705 EEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEE 764
Query: 520 DKAEKTEKKEEEKKDE---EEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTAN 576
K + EK++E+ E EE+ + +K + KE ++G E EE EQ T ++ +
Sbjct: 765 GKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQET---KEKGS 821
Query: 577 SQGRRKGRITRSM 589
+ KG +T +
Sbjct: 822 GREEEKGVVTNGL 834
Score = 35.8 bits (81), Expect = 0.53
Identities = 48/222 (21%), Positives = 81/222 (36%), Gaps = 30/222 (13%)
Query: 1837 SKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHS 1896
S+ +E + E E A E++++E+K+ EV + P P
Sbjct: 559 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 618
Query: 1897 SVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSD 1956
E G K P PKS EE +GK+ + + E+G S
Sbjct: 619 KSPVEEKG--KSPVPKSPVEE----KGKSPVPKS---------------PVEEKG--KSP 655
Query: 1957 SSSSLSSHRYETPSDAIEVISPASSPAP--PQEKLQTYQPEVVKANQAENDPTRQYEGPL 2014
S + ++P V A SP P P E+ ++ + EV K Q E + E P
Sbjct: 656 VPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKS-KAEVGKGEQKEEEEKEVKEAPK 714
Query: 2015 HH-YRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHI 2055
++E P + +P +AE + ++T+ +
Sbjct: 715 EEKVEKKEEKP---KDVPEKKKAESPVKEEAVAEVVTITKSV 753
Score = 32.3 bits (72), Expect = 5.9
Identities = 57/258 (22%), Positives = 98/258 (37%), Gaps = 58/258 (22%)
Query: 169 QNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPV----- 223
+ S +KEEL+ AKVE+ + EE K P P+ PV
Sbjct: 589 EEKSEEVATKEELVAD--------AKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGK 640
Query: 224 SP---PPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIK 280
SP PVE+K +S V + EE K + P+ P + K K
Sbjct: 641 SPVPKSPVEEKGKSPVP------KSPVEE----------KGKSPVSKSPVEEKAKSPVPK 684
Query: 281 TNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTRE 340
+ K K +++E K + +++ EKK ++ ++ P +K ES +E
Sbjct: 685 SPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV----EKKEEKPKDVPEKKKAESPVKE 740
Query: 341 ---------------YYEKQFPEIRKQREQQERFQRVG------QRGAGLSATIARSEH- 378
+ EK+ E K +Q++ ++ G + G+ A +R E
Sbjct: 741 EAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDI 800
Query: 379 EISEIIDGLSEQENNEKQ 396
++ ++G E E K+
Sbjct: 801 AVNGEVEGKEEVEQETKE 818
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 67.8 bits (164), Expect = 1e-10
Identities = 80/408 (19%), Positives = 173/408 (42%), Gaps = 45/408 (11%)
Query: 179 EELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQI 238
EEL + D + E+ + +LK+K +L+E+ + + +S +Q+
Sbjct: 196 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ-------------LVESEKSEIQL 242
Query: 239 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 298
E ++K E A K+ LP ++ + +++ + + + N
Sbjct: 243 NVKELKRKLERA---------KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 293
Query: 299 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRR-----KAKESKTREYYEKQFPEIRKQR 353
+Q+E+K+ ++ +++ E WE+K+ E R + +E K R E + + K R
Sbjct: 294 LNQQQEEKMWRQEEKIQE-WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Query: 354 EQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQEN---NEKQMRQLSVIPPMMFDA 410
Q+E ++ L + E +I E+ + + EQE E++ ++ I
Sbjct: 353 RQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 412
Query: 411 EQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKS 470
EQ + + E K+ + + M W EK ++K + K + + +
Sbjct: 413 EQEAKMWRQEEKIREQEEKIREQEKKM--WRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 470
Query: 471 VPDCVLYYYLTKKNENYKAL------VRRNYGKRRGRNQQIARPS-----QEEKVEEKEE 519
+ + + +K + + V R K + ++I QEEK+ E+EE
Sbjct: 471 IREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEE 530
Query: 520 DKAEKTEK-KEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQ 566
E+ EK +E+E+ +E++++ + +E +E++K+ E+ E+E+
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578
Score = 63.5 bits (153), Expect = 2e-09
Identities = 95/408 (23%), Positives = 176/408 (43%), Gaps = 44/408 (10%)
Query: 175 KLSKEELIQSMDRVDREIAKVEQQILKLKKK---------QQQLEEEAAKPPEPEKPVSP 225
K +L + + V+ E ++++ + +LK+K QQQL+ EA + + VS
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
Query: 226 PPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVM 285
Q + + NR ++ K++ E Q + K+ + K +
Sbjct: 280 KLQAQVEENELW-----NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
Query: 286 RKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQ 345
K +R+ ++E+K+ +R +++M E+K+ R+E KE K RE EK
Sbjct: 335 EK-----MRRQEEMMWEKEEKM-RRQEEMMWEKEEKMRRLEE--MMWEKEEKIRELEEKM 386
Query: 346 FPEIRKQREQQERFQ-----RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQL 400
E K REQ+E+ Q R ++ A + R E +I E + + EQE +K RQ
Sbjct: 387 H-EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE--KKMWRQE 443
Query: 401 SVIPPMMFDAEQRRVKFINMNGLMEDPMKVY-KDRQFMNVWTDHEKEIFKDKFIQHPKNF 459
I EQ +++ E+ + K R+ +W EK ++K + +
Sbjct: 444 EKIH------EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKV 497
Query: 460 GLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEE 519
E K +K + +R K R + ++I QEE ++E+EE
Sbjct: 498 WR----QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIRE--QEEMMQEQEE 551
Query: 520 DKAEKTEKKEEEKKDEEEKDEKEDSKENTKE-KDKIDGTAEETEEREQ 566
E+ EK +E++K ++++ + +E +E K+KI E+ E+E+
Sbjct: 552 KMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
Score = 57.4 bits (137), Expect = 2e-07
Identities = 76/388 (19%), Positives = 173/388 (44%), Gaps = 34/388 (8%)
Query: 174 SKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHR 233
+++ + EL +++ E K+ +Q K+++ +++++E+ K E E+ + + + +
Sbjct: 283 AQVEENELWNRLNQQQEE--KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 340
Query: 234 SIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFF 293
+ +E ++ EE E ++E ++ + + E + + +R++
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQE---- 396
Query: 294 KRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQR 353
++R K REQ+ Q + M E+K+ E R + K+ +E + +IR++
Sbjct: 397 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 456
Query: 354 EQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQR 413
++QE+ + Q R + EI + + EQE KQ ++ M D E++
Sbjct: 457 KRQEQEEMWRQEEK------IREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK 510
Query: 414 RVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPD 473
+ E K++ RQ + EK +++ I+ + ++ E+ +
Sbjct: 511 ---------IREQEEKMW--RQEEKIREQEEKIREQEEKIREQEE--MMQEQEEKMGEQE 557
Query: 474 CVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPS-----QEEKVEEKEEDKAEKTEK- 527
+ + + K +R K R + ++I QEEK+ E+EE E+ EK
Sbjct: 558 EKMQEQEKMRRQEEK--IREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM 615
Query: 528 -KEEEKKDEEEKDEKEDSKENTKEKDKI 554
++EEK E+E+ +E ++ ++++K+
Sbjct: 616 WEQEEKMCEQEEKMQEQEEKMRRQEEKM 643
Score = 45.4 bits (106), Expect = 7e-04
Identities = 36/184 (19%), Positives = 88/184 (47%), Gaps = 13/184 (7%)
Query: 178 KEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQ 237
+E++ + ++V R+ K+ Q K++++++++ + K E E+ + E+K R +
Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ--EEKIREQEE 544
Query: 238 IIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTN-QVMRKKLILFFKRR 296
++ ++ K E+ K+ E + + Q + E I+ + +R++ +++
Sbjct: 545 MMQEQEEKMGEQEEKMQE------QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
Query: 297 NHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQ 356
R+Q E +Q + WE++ E + + +E K R EK + + + R+Q+
Sbjct: 599 EKIREQEEMM----QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654
Query: 357 ERFQ 360
E+ Q
Sbjct: 655 EKMQ 658
Score = 45.1 bits (105), Expect = 9e-04
Identities = 47/205 (22%), Positives = 93/205 (45%), Gaps = 12/205 (5%)
Query: 178 KEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQ 237
+EE I+ + + R+ K+ +Q K++K+++++ + K + E+ + E+K +
Sbjct: 467 QEEKIREQEEIWRQKEKMHEQE-KIRKQEEKVWRQEEKMHDQEEKIREQ--EEKMWRQEE 523
Query: 238 IIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRN 297
I ++ K E+ KI E E + Q E ++ + MR++ K R
Sbjct: 524 KIREQEEKIREQEEKIREQ-----EEMMQEQEEKMGEQEEKMQEQEKMRRQEE---KIRE 575
Query: 298 HARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQE 357
K REQK R +Q + WE++ E + +E K E EK + K +EQ+E
Sbjct: 576 QEEKIREQKEKIR-EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 634
Query: 358 RFQRVGQRGAGLSATIARSEHEISE 382
+ +R ++ + + E ++ E
Sbjct: 635 KMRRQEEKMWEQEVRLRQQEEKMQE 659
Score = 41.6 bits (96), Expect = 0.010
Identities = 100/506 (19%), Positives = 196/506 (38%), Gaps = 69/506 (13%)
Query: 242 ENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARK 301
E+ +KA H+ E L ++E +V+ I T Q ++ L++ + HA K
Sbjct: 108 EDEQKASHQHQ--EALRRELE---------AQVHTIRILTCQKTELQMALYYSQ--HAVK 154
Query: 302 QREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQE---- 357
Q E + +L ++W K +E A + K + Y E+ K+R+
Sbjct: 155 QLEGEARDLISRLHDSW-KFAGELEQALSAVATQKKKADRY---IEELTKERDALSLELY 210
Query: 358 ----RFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQR 413
+ + ++ A L + E E SEI L+ +E K R ++P AE
Sbjct: 211 RNTITDEELKEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEAD 268
Query: 414 RVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPD 473
+ L K+ + +W ++ + + Q K I + E+ +
Sbjct: 269 HLG----KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK----IQEWEEKIQEQE 320
Query: 474 CVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEE---DKAEKTEKKEE 530
+K + +R K R + + + +EEK+ +EE +K EK + EE
Sbjct: 321 --------EKIREQEEKIREQEEKMRRQEEMMWE--KEEKMRRQEEMMWEKEEKMRRLEE 370
Query: 531 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT 590
++EEK + + K + +EK E EE+ Q + R+ Q +R+ + +
Sbjct: 371 MMWEKEEKIRELEEKMHEQEK------IREQEEKRQEEEKIRE----QEKRQEQEAKMWR 420
Query: 591 NEAAAASAAAAAATEEPPPPLPPPPEPISTEP---VETSRWTEEEMEVAKKGLVEHGRNW 647
E +E + E I + E R +EEM ++ + E W
Sbjct: 421 QEEKIREQEEKIREQE--KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 478
Query: 648 AAIAKM-VGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSR-----KPREERDVSQCES 701
KM K Q + + ++ H+ + +++ ++K R + +EE+ Q E
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
Query: 702 VASTVSAQEDEDIEASNEEENPEDSE 727
+ ++++ + +EE ++ E
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQE 564
Score = 37.4 bits (85), Expect = 0.18
Identities = 45/228 (19%), Positives = 97/228 (42%), Gaps = 19/228 (8%)
Query: 175 KLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPE---KPVSPPPVEQK 231
K+ +EE Q + + R+ K+ +Q ++K++ E+E + E + + E+K
Sbjct: 451 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK 510
Query: 232 HRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLIL 291
R + ++ + K E+ KI E E Q + K+ + K + +
Sbjct: 511 IREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK----- 565
Query: 292 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK 351
+R+ +++E+KI ++ +++ E EK ++ E K RE E + K
Sbjct: 566 -MRRQEEKIREQEEKIREQKEKIREQEEKIWEQ----------EEKIREQEEMMQEQEEK 614
Query: 352 QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQ 399
EQ+E+ ++ + R E ++ E L +QE ++ ++
Sbjct: 615 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 32.3 bits (72), Expect = 5.9
Identities = 46/236 (19%), Positives = 94/236 (39%), Gaps = 24/236 (10%)
Query: 513 KVEEKEEDKAEKTEKKE---EEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATP 569
++ +++E+K + E+K EEK E+E+ +E ++ ++++K+ E E+E+
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Query: 570 RGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWT 629
R + + + R+ M + E+ E I + E R
Sbjct: 353 RQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ---------EKIREQ--EEKRQE 401
Query: 630 EEEMEVAKKGLVEHGRNWAAIAKM--VGTKSEAQCKNFYFNYKRRHNLDNLLQQHK-QKT 686
EE++ +K + + W K+ K Q K + ++ H + + ++ K Q+
Sbjct: 402 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ 461
Query: 687 SRKPREERDVSQCESV-ASTVSAQEDEDIEASNE-----EENPEDSEVEAVKPSED 736
R+E + + E + E E I E EE D E E ++ E+
Sbjct: 462 EEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE-EKIREQEE 516
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 67.8 bits (164), Expect = 1e-10
Identities = 104/528 (19%), Positives = 212/528 (40%), Gaps = 82/528 (15%)
Query: 444 EKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQ 503
+KEI KDK E++ P+ + +T K + + K R + +
Sbjct: 140 KKEIHKDK--------------TEKQEKPERKIQTKVTHKEKE------KGKEKVREKEK 179
Query: 504 QIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEE 563
+ + +EK+E+KE+ + + K++++ K E+ +EK + +++K+ TA + +E
Sbjct: 180 PEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKE 239
Query: 564 REQATPRGRKTANSQGRRKGRITRSMTNEAAAASA------AAAAATEEPPPPLPPP-PE 616
Q TP K + + K +++ + A P +PPP P
Sbjct: 240 -VQKTP--SKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPT 296
Query: 617 PISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLD 676
++ P S EE+ KK K V ++++ + K + K++ +
Sbjct: 297 EQASRPTPASPALEEKEGEKKKA-----------EKKVTSETKKKEKE---DIKKKSEKE 342
Query: 677 NLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSED 736
+ K++ + ++ + +A+ +A++DE E S + + P + E K E
Sbjct: 343 TAIDVEKKEPGKASETKQGTVK---IAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEK 399
Query: 737 -----SPENATSRGNTEPA-VELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISA 790
P + + ++ P+ +++ TE A ++++ P + E T
Sbjct: 400 KEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTT-------- 451
Query: 791 ETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRAS 850
+T EQ ++E S + S+ K E +VP + K E + K+ + +A
Sbjct: 452 KTVEQ--EIRKEKSGKTSSILKDKEPIKGK----EEKVPASLKEK-EPETKKDEKMSKAG 504
Query: 851 EKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGE----PERQRMFPMDSKP- 905
++V+P+ L Q ++PEPQ ++ S + + PE+ KP
Sbjct: 505 KEVKPKPPQL---QGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKT---VSHGKPE 558
Query: 906 -SLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGT 952
+L ++ + KP P + +HR P + + P P GT
Sbjct: 559 EKVLKQVKAVTIEKTAKPKP--TKKAEHREREPPSIKTDKPKPTPKGT 604
Score = 40.8 bits (94), Expect = 0.016
Identities = 99/566 (17%), Positives = 225/566 (39%), Gaps = 86/566 (15%)
Query: 175 KLSKEEL--IQSMDRVDREIAKVEQQILKLKK-----KQQQLEEEAAKPPEPEK-PVSPP 226
K+ K+E +++ + ++ E+ K KK KQ+++++ AAK E +K P P
Sbjct: 189 KIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPK 248
Query: 227 PVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYN--QPSDTKVYHENIKTNQV 284
E K ++ V ++ +K + A + +++ ++ +P + + T Q
Sbjct: 249 EKEDKEKAAV----SKHEQKDQYAFCRY-----MIDIFVHGDLKPGQSPAIPPPLPTEQA 299
Query: 285 MRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEK 344
R A E+K ++KA++ T E +K
Sbjct: 300 ---------SRPTPASPALEEK--------------------EGEKKKAEKKVTSETKKK 330
Query: 345 QFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIP 404
+ +I+K+ E++ + S T + ++ E++ + K+ ++ + +
Sbjct: 331 EKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVE 390
Query: 405 PMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIAS 464
++++ K + + V D+Q + T+ KE I+ +
Sbjct: 391 QPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQ-VKAKTERAKEEIGAVSIKK-----AVPG 444
Query: 465 YLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEK 524
E K+ + + K+ + + ++ +G+ +++ +E++ E K+++K K
Sbjct: 445 KKEEKTTK--TVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSK 502
Query: 525 TEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGR 584
KE + K + + +KE+ E +K+ +E+ + +Q + KT S G+ + +
Sbjct: 503 A-GKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTV-SHGKPEEK 560
Query: 585 I---TRSMTNEAAA---ASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKK 638
+ +++T E A + A EPP P+P E + +++ E+++K
Sbjct: 561 VLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEK 620
Query: 639 GLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKP-REERDVS 697
E + V T+ E+ LQ H + KP R +DV
Sbjct: 621 ESKEKADMKHLREEKVSTRKES------------------LQLHNVTKAEKPARVSKDV- 661
Query: 698 QCESVASTVSAQEDEDIEASNEEENP 723
E V ++ A+E + + ++++P
Sbjct: 662 --EDVPASKKAKEGTEDVSPTKQKSP 685
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 67.4 bits (163), Expect = 2e-10
Identities = 101/439 (23%), Positives = 189/439 (43%), Gaps = 58/439 (13%)
Query: 175 KLSKEELIQSMDRVDREIAKVEQQILKLKKK---------QQQLEEEAAKPPEPEKPVSP 225
K +L + + V+ E ++++ + +LK+K QQQL+ EA + + VS
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
Query: 226 PPVEQKHRSIV--QIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQ 283
Q + + ++ + K + KI E E + Q + E I+ +
Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW-----EEKIQEQEEKIREQEEKIREQE 334
Query: 284 V-MRKKLILFFKRRNHARKQRE-----QKICQRYDQLMEAWEKKVDRIENNPRRKAKESK 337
MR++ + +++ R+Q E ++ +R +++M WEK+ KE K
Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM--WEKEEKMRRQEEMMWEKEEK 392
Query: 338 TREYYEKQFPEIRKQREQQERFQ-----RVGQRGAGLSATIARSEHEISEIIDGLSEQEN 392
RE EK E K REQ+E+ Q R ++ A + R E +I E + + EQE
Sbjct: 393 IRELEEKMH-EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
Query: 393 N----EKQMRQLSVIPPMMFDAEQRRV-----KFINMNGLMEDPMKVYKD-----RQFMN 438
E+++ + I EQ + K + K+++ +Q
Sbjct: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEK 511
Query: 439 VWTDHEKEIFKDKFI---------QHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKA 489
VW EK +++ I Q K + E + + + + K+ E
Sbjct: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571
Query: 490 LVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEK--KEEEKKDEEEKDEKEDSKEN 547
+ R+ K R + +++ R QEEK+ E+EE + E+ EK K+EEK E+E+ +E ++
Sbjct: 572 MWRQEE-KIREQEEKVWR--QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
Query: 548 TKEKDKIDGTAEETEEREQ 566
++++KI E T+E+E+
Sbjct: 629 REQEEKIREQEEMTQEQEE 647
Score = 63.2 bits (152), Expect = 3e-09
Identities = 74/404 (18%), Positives = 185/404 (45%), Gaps = 28/404 (6%)
Query: 178 KEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQ 237
+E++ + +++ K+++Q K++++++++ E+ K E+ + + + + +
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 238 IIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRN 297
+E ++ EE E + E ++ + + E + + +R++ ++R
Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE----EKRQ 414
Query: 298 HARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTRE---YYEKQFPEIRKQRE 354
K REQ+ Q + M E+K+ E R + K+ +E + +++ E K++E
Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474
Query: 355 QQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRR 414
Q+E +++ + I R + ++ E + + +QE EK RQ I ++
Sbjct: 475 QEEMWRQ--EEKIHEQEEIWRQKEKMHEQEEKIRKQE--EKVWRQEEKIREQEEKIREQE 530
Query: 415 VKFINMNGLMEDPMKVYKDRQFMN----VWTDHEKEIFKDKFIQHPKNFGLIASYLERKS 470
K + + +++++ + M+ +W + +++ +DK + + I E+
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK---IREQEEKVW 587
Query: 471 VPDCVLYYYLTKKNENYKAL------VRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEK 524
+ + K+ E + + +R K + + ++I QEEK+ E+EE E+
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE--QEEKIREQEEMTQEQ 645
Query: 525 TEK--KEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQ 566
EK ++EEK E+E+ +E + ++++KI ++ E+E+
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEE 689
Score = 58.5 bits (140), Expect = 8e-08
Identities = 84/410 (20%), Positives = 179/410 (43%), Gaps = 40/410 (9%)
Query: 178 KEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQ 237
+E + + +++ R+ + ++ K++++++ + E+ K E+ + E+K R + +
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK--EEKIRELEE 398
Query: 238 IIYD-----ENRKKAEEAHKIFEG-LGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLIL 291
+++ E +K +E KI E + E ++ Q + E I+ + KK+
Sbjct: 399 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE---KKMWR 455
Query: 292 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAK----ESKTREYYEKQFP 347
++ + K RE++ Q +++ E+K+ E R+K K E K R+ EK +
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQ-EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR 514
Query: 348 EIRKQREQQERFQRVGQRGAGLSATIARSE---------HEISEIIDGLSEQENNEKQMR 398
+ K REQ+E+ + ++ I E HE +I + QE +K R
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574
Query: 399 QLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKN 458
Q I EQ + + E K + Q +W EK +++ IQ +
Sbjct: 575 QEEKI------REQEEKVWRQEEKIREQEEK--RQEQEEKMWKQEEKIREQEEKIQEQEE 626
Query: 459 FGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKE 518
I E+ + + K E + + + + + + Q+ QEEK+ E+E
Sbjct: 627 --KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ---EEKMQEQEETMWRQEEKIREQE 681
Query: 519 EDKAEKTEKKEEEKKDEEEKDEK--EDSKENTKEKDKIDGTAEETEEREQ 566
+ E+ EK E+++ +E++EK E ++ ++++K+ E+ +E+
Sbjct: 682 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
Score = 57.8 bits (138), Expect = 1e-07
Identities = 84/384 (21%), Positives = 154/384 (40%), Gaps = 76/384 (19%)
Query: 178 KEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQ 237
+EE Q +++ RE K ++Q K+ ++++++ E+ K E EK + E+K +
Sbjct: 409 QEEKRQEEEKI-REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ--EEKIHEQEK 465
Query: 238 IIYDENRKKAEEAHKIFEGLGPKVEL-----PLYNQPS-----DTKVYHENIKTNQVMRK 287
I +E R++ EE + E + + E+ ++ Q + KV+ + K + K
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEK 525
Query: 288 KLILFFKRRNHARKQREQKICQRYDQLMEAWEK---KVDRIENNPRRKAKESKTREYYEK 344
K K REQ+ R ++ M EK + R E + +E K RE EK
Sbjct: 526 IREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK 585
Query: 345 QFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIP 404
+ + K REQ+E+ Q ++ I E +I E + + EQE ++ +++
Sbjct: 586 VWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT--- 642
Query: 405 PMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIAS 464
EQ + E K+ + + M W EK
Sbjct: 643 -----QEQEEKMGEQEEKMCEQEEKMQEQEETM--WRQEEK------------------- 676
Query: 465 YLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEK 524
+R K R + ++I QEE ++E+EE E+
Sbjct: 677 --------------------------IREQEKKIREQEEKIRE--QEEMMQEQEEKMWEQ 708
Query: 525 TEK---KEEEKKDEEEKDEKEDSK 545
EK +EE+ +++EEK +++ K
Sbjct: 709 EEKMCEQEEKMQEQEEKMRRQEEK 732
Score = 47.0 bits (110), Expect = 2e-04
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 9/193 (4%)
Query: 175 KLSKEELIQSM-DRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHR 233
K+ +EE Q D++ R+ K+ +Q K+ ++++++ E+ K E E+ + E+K R
Sbjct: 558 KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ--EEKIR 615
Query: 234 SIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFF 293
+ I ++ K E+ KI E E + K+ + K +
Sbjct: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE 675
Query: 294 KRRNHARKQREQ--KICQRYDQLMEA----WEKKVDRIENNPRRKAKESKTREYYEKQFP 347
K R +K REQ KI ++ + + E WE++ E + + +E K R EK +
Sbjct: 676 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 735
Query: 348 EIRKQREQQERFQ 360
+ + R+Q+E+ Q
Sbjct: 736 QEVRLRQQEEKMQ 748
Score = 46.2 bits (108), Expect = 4e-04
Identities = 132/685 (19%), Positives = 246/685 (35%), Gaps = 94/685 (13%)
Query: 242 ENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARK 301
E+ +KA H+ E L ++E +V+ I T Q ++ L++ + HA K
Sbjct: 108 EDEQKASHQHQ--EALRRELE---------AQVHTIRILTCQKTELQMALYYSQ--HAVK 154
Query: 302 QREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQE---- 357
Q E + +L ++W K +E A + K + Y E+ K+R+
Sbjct: 155 QLEGEARDLISRLHDSW-KFAGELEQALSAVATQKKKADRY---IEELTKERDALSLELY 210
Query: 358 ----RFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQR 413
+ + ++ A L + E E SEI L+ +E K R ++P AE
Sbjct: 211 RNTITDEELKEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEAD 268
Query: 414 RVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPD 473
+ L K+ + +W ++ + + Q K I + E+ +
Sbjct: 269 HLG----KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK----IQEWEEKIQEQE 320
Query: 474 CVLYYYLTKKNENYKALVRRNY----GKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKE 529
+ K E + + R+ + + R Q+ +EEK+ +EE EK EK
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 380
Query: 530 EEKKDEEEKDEK-EDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRS 588
+++ EK+EK + +E E++KI E+ +E E+ Q +R+ + +
Sbjct: 381 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI--------REQEKRQEQEAKM 432
Query: 589 MTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPV---ETSRWTEEEMEVAKKGLVEHGR 645
E +E + E I + E R +EEM ++ + E
Sbjct: 433 WRQEEKIREQEEKIREQEKK--MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
Query: 646 NWAAIAKM--VGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKP----------REE 693
W KM K Q + + ++ + +++ ++K R+ REE
Sbjct: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREE 550
Query: 694 RDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVEL 753
+ + E + QE ED + +EE + E + + E E R E
Sbjct: 551 EKMHEQEKIWEEEKRQEQED-KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE----- 604
Query: 754 EPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAE-EGSVCD 812
E + K E E + + I + E+M +Q+E E E +C+
Sbjct: 605 ----EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ--EEMTQEQEEKMGEQEEKMCE 658
Query: 813 PPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPE 872
E + E ++ + R EK E+ + Q+ Q E
Sbjct: 659 ----------------QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQE 702
Query: 873 PQSDNDSSATCSADEDVDGEPERQR 897
+ C +E + + E+ R
Sbjct: 703 EKMWEQEEKMCEQEEKMQEQEEKMR 727
Score = 43.5 bits (101), Expect = 0.003
Identities = 43/224 (19%), Positives = 99/224 (44%), Gaps = 15/224 (6%)
Query: 178 KEELIQSMDRVDREIAKV-EQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIV 236
+EE I+ + + RE K+ EQ+ + ++K+Q+ E++ + E + Q+ +
Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK--- 592
Query: 237 QIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRR 296
I ++ K+ E+ K++ K E + Q + E I+ + ++ + +
Sbjct: 593 --IREQEEKRQEQEEKMW-----KQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ 645
Query: 297 NHARKQREQKICQRYDQLMEA----WEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQ 352
++E+K+C++ +++ E W ++ E + + +E K RE E + K
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 705
Query: 353 REQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQ 396
EQ+E+ ++ + R E ++ E L +QE ++
Sbjct: 706 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 67.0 bits (162), Expect = 2e-10
Identities = 81/418 (19%), Positives = 176/418 (42%), Gaps = 40/418 (9%)
Query: 179 EELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQI 238
EEL + D + E+ + +LK+K +L+E+ + + +S +Q+
Sbjct: 257 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ-------------LVESEKSEIQL 303
Query: 239 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 298
E ++K E A K+ LP ++ + +++ + + + N
Sbjct: 304 NVKELKRKLERA---------KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 354
Query: 299 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRR-----KAKESKTREYYEKQFPEIRKQR 353
+Q+E+K+ ++ +++ E WE+K+ E R + +E K R E + + K R
Sbjct: 355 LNQQQEEKMWRQEEKIQE-WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 413
Query: 354 EQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQEN---NEKQMRQLSVIPPMMFDA 410
Q+E ++ + E +I E+ + + EQE E++ ++ I
Sbjct: 414 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 473
Query: 411 EQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKS 470
EQ + + E K+ + + M W EK ++K + K + + +
Sbjct: 474 EQEAKMWRQEEKIREQEEKIREQEEKM--WRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 531
Query: 471 VPDCVLYYYLTKKNENYKALVRRNYGK-----RRGRNQQIARPSQEEKVEEKEEDKAEKT 525
+ + + +K + +R+ K + +Q+ QEEKV +EE E+
Sbjct: 532 IREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE 591
Query: 526 EK--KEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRR 581
EK ++EEK E+E+ +E ++ ++++K+ E+ +E+E+ R + Q ++
Sbjct: 592 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK 649
Score = 66.2 bits (160), Expect = 4e-10
Identities = 96/409 (23%), Positives = 178/409 (43%), Gaps = 51/409 (12%)
Query: 175 KLSKEELIQSMDRVDREIAKVEQQILKLKKK---------QQQLEEEAAKPPEPEKPVSP 225
K +L + + V+ E ++++ + +LK+K QQQL+ EA + + VS
Sbjct: 281 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 340
Query: 226 PPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVM 285
Q + + NR ++ K++ E Q + K+ + K +
Sbjct: 341 KLQAQVEENELW-----NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 395
Query: 286 RKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQ 345
K +R+ ++E+K+ +R +++M WEK+ KE K RE EK
Sbjct: 396 EK-----MRRQEEMMWEKEEKM-RRQEEMM--WEKEEKMRRQEEMMWEKEEKIRELEEKM 447
Query: 346 FPEIRKQREQQERFQ-----RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQL 400
E K REQ+E+ Q R ++ A + R E +I E + + EQE EK RQ
Sbjct: 448 H-EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE--EKMWRQE 504
Query: 401 SVIPPMMFDAEQRRVKFINMNGLMEDPMKVY-KDRQFMNVWTDHEKEIFKDKFIQHPKNF 459
I EQ +++ E+ + K R+ +W EK +++ I+ +
Sbjct: 505 EKIH------EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE- 557
Query: 460 GLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEE 519
+ + + + D +K + V R K R + ++I QEEK+ E+EE
Sbjct: 558 ---KMWRQEEKMHD------QEEKIREQEEKVWRQEEKIREQEEKIRE--QEEKIREQEE 606
Query: 520 DKAEKTEK--KEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQ 566
E+ EK ++EEK E+E+ +E ++ ++++KI ++ E+E+
Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Score = 58.9 bits (141), Expect = 6e-08
Identities = 81/387 (20%), Positives = 173/387 (44%), Gaps = 57/387 (14%)
Query: 178 KEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQ 237
+E++ + +++ K+++Q K++++++++ E+ K E+ + E+K R +
Sbjct: 360 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK--EEKMRRQEE 417
Query: 238 IIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRN 297
+++++ K + ++E EL + HE K + K+ R
Sbjct: 418 MMWEKEEKMRRQEEMMWEKEEKIRELE--------EKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 298 HARKQREQKICQRYDQLMEAWEKKVDRIEN--------NPRRKAKESKTREYYEKQFPEI 349
R+++E K+ ++ +++ E EK ++ E + + K +E + R+ E+ + +
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 350 RKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFD 409
K REQ+E I R + +I E + + +QE EK RQ M D
Sbjct: 530 EKIREQEE---------------IWRQKEKIHEQEEKIRKQE--EKMWRQ----EEKMHD 568
Query: 410 AEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERK 469
E++ + E KV+ RQ + EK +++ I+ + + E K
Sbjct: 569 QEEK---------IREQEEKVW--RQEEKIREQEEKIREQEEKIREQEE---MTQEQEEK 614
Query: 470 SVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEK-- 527
+K + + +RR K R + ++I QEEK+ E+EE E+ EK
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE--QEEKIREQEEMMQEQEEKMW 672
Query: 528 KEEEKKDEEEKDEKEDSKENTKEKDKI 554
++EEK E+E+ +E ++ ++++K+
Sbjct: 673 EQEEKMCEQEEKMQEQEEKMRRQEEKM 699
Score = 39.7 bits (91), Expect = 0.037
Identities = 102/503 (20%), Positives = 195/503 (38%), Gaps = 68/503 (13%)
Query: 242 ENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARK 301
E+ +KA H+ E L ++E +V+ I T Q ++ L++ + HA K
Sbjct: 169 EDEQKASHQHQ--EALRRELE---------AQVHTIRILTCQKTELQMALYYSQ--HAVK 215
Query: 302 QREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQE---- 357
Q E + +L ++W K +E A + K + Y E+ K+R+
Sbjct: 216 QLEGEARDLISRLHDSW-KFAGELEQALSAVATQKKKADRY---IEELTKERDALSLELY 271
Query: 358 ----RFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQR 413
+ + ++ A L + E E SEI L+ +E K R ++P AE
Sbjct: 272 RNTITDEELKEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEAD 329
Query: 414 RVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPD 473
+ L K+ + +W ++ + + Q K I + E+ +
Sbjct: 330 HLG----KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK----IQEWEEKIQEQE 381
Query: 474 CVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEE---DKAEKTEKKEE 530
+K + +R K R + + + +EEK+ +EE +K EK ++EE
Sbjct: 382 --------EKIREQEEKIREQEEKMRRQEEMMWE--KEEKMRRQEEMMWEKEEKMRRQEE 431
Query: 531 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT 590
++EEK + + K + +EK E EE+ Q + R+ Q +R+ + +
Sbjct: 432 MMWEKEEKIRELEEKMHEQEK------IREQEEKRQEEEKIRE----QEKRQEQEAKMWR 481
Query: 591 NEAAAASAAAAAATEEPPPPLPPPPEPISTEP---VETSRWTEEEMEVAKKGLVEHGRNW 647
E +E + E I + E R +EEM ++ + E W
Sbjct: 482 QEEKIREQEEKIREQE--EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Query: 648 AAIAKM--VGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESV-AS 704
K+ K Q + + ++ H+ + +++ ++K R +EE+ Q E +
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWR--QEEKIREQEEKIREQ 597
Query: 705 TVSAQEDEDIEASNEEENPEDSE 727
+E E++ EE+ E E
Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEE 620
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 66.6 bits (161), Expect = 3e-10
Identities = 92/420 (21%), Positives = 153/420 (36%), Gaps = 44/420 (10%)
Query: 505 IARPSQEEKVEEKEEDKAEKTEKKEEEKKDEE--EKDEKEDSKENTKEKDKIDGTAEETE 562
+ ++E +V E+ ++ EK E KEEE K+EE E++E E +E TK + + E E
Sbjct: 457 VEEQTEETQVTEEVTEEEEK-EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKE 515
Query: 563 EREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEP 622
+ + A ++ K ++ + + A + PP P + + P
Sbjct: 516 AKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSP 575
Query: 623 VET---SRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLL 679
E + E AK A KS A+ K+ +
Sbjct: 576 AEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKS------------PVK 623
Query: 680 QQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEA--------- 730
++ K K E+ E S A+ E EA + E+ + EA
Sbjct: 624 EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSP 683
Query: 731 VKPSEDSPENATSRGNTE---PAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDS 787
VK SPE A S E P P E A S + + + E ++ V +
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEE 743
Query: 788 I-------SAETAEQMDVDQQEHSA----EEGSVCDPPPATKADSVDVEVRVPENHASKV 836
S E A+ +DV E E S D P V EV+ PE S +
Sbjct: 744 AKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL 803
Query: 837 EGD-NTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSS-ATCSADEDVDGEPE 894
+ D E+++ + E P E+ Q++ + P +++ + + AT +E D + E
Sbjct: 804 KEDAKAPEKEIPKKEEVKSPVKEE-EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE 862
Score = 55.1 bits (131), Expect = 8e-07
Identities = 87/410 (21%), Positives = 154/410 (37%), Gaps = 28/410 (6%)
Query: 497 KRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKD--EEEKDEKEDSKENTKEKDKI 554
K + ++ A+ E K KEE K+ K E+ K +EE E +K KE+ K
Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKS 662
Query: 555 DGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEE----PPPP 610
A+ + E +P K+ + +S E A + A + +E P
Sbjct: 663 PEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKA 722
Query: 611 LPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGT--KSEAQCKNFYFN 668
P E T S EE K E + + T K EA+ F
Sbjct: 723 KSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP 782
Query: 669 YKRRHNL-DNLLQQHKQKTSRK---PREERDVSQCESVASTVSAQEDEDIEASNEEENPE 724
K + + + + K K+ K E+++ + E V S V +E+E + +E P+
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV--KEEEKPQEVKVKEPPK 840
Query: 725 DSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQV 784
+E E + + E S+ P E P + P AV K ++ E+ + +
Sbjct: 841 KAEEEKAPATPKTEEKKDSKKEEAPKKE-APKPKVEEKKEP--AVEKPKESKVEAKKEEA 897
Query: 785 NDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEG----DN 840
D T E+ + + E+ + K + D + + P A K E +
Sbjct: 898 EDKKKVPTPEK-EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956
Query: 841 TKERDLDRASEK----VEPRDEDLVVAQQINAQRPEPQSDNDSSATCSAD 886
TKE + EK + +++D ++++ +P+ + SS+T D
Sbjct: 957 TKEEKAKKPEEKPKTEAKAKEDDKTLSKE--PSKPKAEKAEKSSSTDQKD 1004
Score = 50.8 bits (120), Expect = 2e-05
Identities = 95/499 (19%), Positives = 196/499 (39%), Gaps = 39/499 (7%)
Query: 144 KKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLK 203
+++ A GG+ E S P + + SP K + ++ ++E AK ++ +
Sbjct: 490 EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP-EKEEAKSPAEVKSPE 548
Query: 204 KKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGP-KVE 262
K + +EEA PPE + SP E K + V+ EEA E P K +
Sbjct: 549 KAKSPAKEEAKSPPEAK---SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605
Query: 263 LPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKV 322
P+ + +K ++ K ++ +++ + + + EA K
Sbjct: 606 SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEA--KSP 663
Query: 323 DRIENNPRRKAK---ESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSATIARS-EH 378
++ ++ + +AK ++K+ E + PE K ++E + ++ A+S E
Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA--KSPEKAKSPVKEEAKSPEK 721
Query: 379 EISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRR---VKFINMNGLMEDPMKVYKDRQ 435
S + + E + +++ + P E+ + VK ++ + D+
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF 781
Query: 436 FMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNY 495
+ ++E+ + + P A K +P K E K+ V+
Sbjct: 782 PEKAKSPVKEEVKSPEKAKSPLKEDAKAP---EKEIP----------KKEEVKSPVKEEE 828
Query: 496 GKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEK---D 552
+ + ++ + ++EEK + + +K KKEE K E K + E+ KE EK
Sbjct: 829 KPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES 888
Query: 553 KIDGTAEETEEREQA-TPRGRKTA------NSQGRRKGRITRSMTNEAAAASAAAAAATE 605
K++ EE E++++ TP A +++ + K + + ++A A + A +
Sbjct: 889 KVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK 948
Query: 606 EPPPPLPPPPEPISTEPVE 624
E P E + +P E
Sbjct: 949 EAAPEKKDTKEEKAKKPEE 967
Score = 50.8 bits (120), Expect = 2e-05
Identities = 68/311 (21%), Positives = 114/311 (36%), Gaps = 43/311 (13%)
Query: 512 EKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRG 571
EK + +++A+ EK + K+E + EK S E K D A+ + E +P
Sbjct: 720 EKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPAD 779
Query: 572 RKTANSQGRRKGRI-----TRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETS 626
+ ++ K + +S E A A EE P+ +P + E
Sbjct: 780 KFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPP 839
Query: 627 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKT 686
+ EEE A E K K EA ++ +++ K+
Sbjct: 840 KKAEEEKAPATPKTEE---------KKDSKKEEAP---------KKEAPKPKVEEKKEPA 881
Query: 687 SRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEV-EAVKPSEDS------PE 739
KP+E + V + ED+ + E+E P EV E KP E + P+
Sbjct: 882 VEKPKESK-------VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934
Query: 740 NATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKP------AEDESVETQVNDSISAETA 793
+A ++ ++PA + E E + P KP ED+ ++ AE A
Sbjct: 935 DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKA 994
Query: 794 EQMDVDQQEHS 804
E+ Q+ S
Sbjct: 995 EKSSSTDQKDS 1005
Score = 45.8 bits (107), Expect = 5e-04
Identities = 103/497 (20%), Positives = 199/497 (40%), Gaps = 66/497 (13%)
Query: 140 SADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQI 199
S + K PA K EA S P + P ++ SP+++ E +S + E AK +
Sbjct: 546 SPEKAKSPA---KEEAKSPPEAKSP-EKEEAKSPAEVKSPEKAKSPAK---EEAKSPAEA 598
Query: 200 LKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIYDENRKKA--EEAHKIFEGL 257
+K + ++EEA P E + PV +++ +S ++ E K EEA +
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPV-----KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK 653
Query: 258 GPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARK--QREQKICQRYDQLM 315
P+ E + + + V E K+ + + + K A+ + E K ++ +
Sbjct: 654 SPEKEEAKSPEKAKSPVKAE-AKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV 712
Query: 316 EAWEKKVDRIENNPRRKAK---ESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSAT 372
+ K ++ ++ + +AK ++K+ E + PE K E+ + +
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE 772
Query: 373 IARS------EHEISEIIDGLSEQENNEKQMRQLSVIP------------PMMFDAEQRR 414
ARS E S + + + E + +++ + P P+ + + +
Sbjct: 773 EARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQE 832
Query: 415 VKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERK--SVP 472
VK + E P K +++ T+ +K+ K+ + PK E+K +V
Sbjct: 833 VK------VKEPPKKAEEEKAPATPKTEEKKDSKKE---EAPKKEAPKPKVEEKKEPAVE 883
Query: 473 DCVLYYYLTKKNE---NYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKA------- 522
KK E K + ++ A+P ++ +V +KE D A
Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943
Query: 523 --EKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKT--ANSQ 578
EK E E+K +EEK +K + K T+ K K D ++T +E + P+ K ++S
Sbjct: 944 PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKED---DKTLSKEPSKPKAEKAEKSSST 1000
Query: 579 GRRKGRITRSMTNEAAA 595
++ + T + AA
Sbjct: 1001 DQKDSKPPEKATEDKAA 1017
Score = 38.5 bits (88), Expect = 0.082
Identities = 110/529 (20%), Positives = 192/529 (36%), Gaps = 39/529 (7%)
Query: 82 PQERRTSYEPFHPGPSPVDHDS---LESKRPRLEQV-SDSHFQRVSAAVLPLVHPL---P 134
P E S P SPV ++ E+K P E+ S + + A P P
Sbjct: 505 PAEEAAS--PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP 562
Query: 135 EGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLS---KEELIQSMDRVD-- 189
E + K PA E SP + + SP K KEE +
Sbjct: 563 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPV 622
Query: 190 REIAKVEQQILKLKKKQQQLEEEA-----AKPPEPEKPVSPPPVEQKHRSIVQIIYDENR 244
+E AK ++ +K + +EEA AK PE E+ SP +K +S V+ ++
Sbjct: 623 KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP----EKAKSPVKA-EAKSP 677
Query: 245 KKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARKQRE 304
+KA+ K K + P+ + + +K +K K ++ +
Sbjct: 678 EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAK 737
Query: 305 QKICQ--RYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQRV 362
+ + + + ++ EK +P K + +FPE K ++E +
Sbjct: 738 SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEE-VKSP 796
Query: 363 GQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINMNG 422
+ + L E EI + + S + EK PP AE+ +
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK--AEEEKAPATPKTE 854
Query: 423 LMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLE---RKSVPDCVLYYY 479
+D K ++ EK K+ ++ PK + A E +K VP
Sbjct: 855 EKKDSKKEEAPKKEAPKPKVEEK---KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAP 911
Query: 480 L-TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEK--KEEEKKDEE 536
+ E+ K + K+ + + PS+ + +E +K + E+ K+ E+K +
Sbjct: 912 AKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKT 971
Query: 537 EKDEKEDSKENTKEKDKIDG-TAEETEEREQATPRGRKTANSQGRRKGR 584
E KED K +KE K AE++ +Q + + A KG+
Sbjct: 972 EAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 64.7 bits (156), Expect = 1e-09
Identities = 81/426 (19%), Positives = 179/426 (42%), Gaps = 53/426 (12%)
Query: 175 KLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV---EQK 231
K+ +E+ +Q ++ R+ + Q+ +++++++++ EE E E+ + EQ+
Sbjct: 425 KMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 232 HRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHE------NIKTNQVM 285
+ Q E ++K E K+ E E ++ Q + E + + M
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQ-----EEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 539
Query: 286 RKKLILFFKRRNHARKQREQKIC---QRYDQLMEAWEKKV----DRIENNPRRKAKESKT 338
R++ +++ R Q EQK+ +R ++ + EKK +++ R + +E K
Sbjct: 540 REQEDQMWEQEEKMRDQ-EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM 598
Query: 339 REYYEKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMR 398
RE E + K +EQ+E+ Q ++ + E ++ E + + EQE + +
Sbjct: 599 REEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ 658
Query: 399 QLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKN 458
+L +++ E K + E K+++ + + EK+ + + ++ +
Sbjct: 659 RLPEQKEKLWEHE----KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE- 713
Query: 459 FGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKE 518
S ER+ K E + + R Q+ QEEK++E+E
Sbjct: 714 -----SMREREK-----------KMREEEEMM----------REQEEKMQEQEEKMQEQE 747
Query: 519 EDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQ 578
E+ E+ EK E+++ E+ + KE E +K+ + E+ E+ + K +
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Query: 579 GRRKGR 584
+ +G+
Sbjct: 808 EKMRGQ 813
Score = 62.4 bits (150), Expect = 5e-09
Identities = 120/654 (18%), Positives = 250/654 (38%), Gaps = 70/654 (10%)
Query: 179 EELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQI 238
EEL + D + E+ + +LKKK +L+E+ P+ + +S +Q+
Sbjct: 200 EELTKERDALSLELYRNTITNEELKKKNAELQEKL-------------PLAESEKSEIQL 246
Query: 239 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMR---KKLILFFKR 295
E ++K E A K LP Q + E + + +R KK+ R
Sbjct: 247 NVKELKRKLERA---------KFLLP---QVQTNTLQEEMWRQEEELREQEKKI-----R 289
Query: 296 RNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQ 355
+ + R+++ + + M E+K+ R E R + KE + +E ++ E+R+Q EQ
Sbjct: 290 KQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQ 349
Query: 356 -QERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQ-LSVIPPMMFDAEQR 413
QE+ +++ ++ + E ++ + L EQE ++ Q + M++ ++R
Sbjct: 350 MQEQEEKMWEQ----EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER 405
Query: 414 -RVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVP 472
R K M + +V K R+ + +K +++ +Q + + +
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEET 465
Query: 473 DCVLYYYLTKKNENYKALVRRNYGKRRGRNQ------QIARPSQEEKVEEKEEDKAEKTE 526
+ K+ EN + + ++R Q Q QEEK+ E+EE ++ E
Sbjct: 466 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 525
Query: 527 KKEEEKK--DEEEKDEKEDSKENTKEK---------DKIDGTAEETEEREQATPRGRKTA 575
+EKK +E+ E+ED +EK D+ + ++T+E+E+ T +
Sbjct: 526 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM 585
Query: 576 NSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEE--M 633
+ R + R + E +E + E W +EE
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEE-----------KMQEQEEKMWEQEEKMQ 634
Query: 634 EVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREE 693
E +K + + W KM + + K + +++ + + +Q ++ ++ E+
Sbjct: 635 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK 694
Query: 694 RDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVEL 753
+ Q + +E+E + ++ E+ + + E E +
Sbjct: 695 KTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE 754
Query: 754 EPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEE 807
E E +P K E + Q + I + + D +++ EE
Sbjct: 755 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEE 808
Score = 55.1 bits (131), Expect = 8e-07
Identities = 76/396 (19%), Positives = 168/396 (42%), Gaps = 70/396 (17%)
Query: 168 DQNASPSKLSKEELIQSMDRVD--REIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSP 225
DQ K ++E+ ++ D+ + RE ++ ++ K++++++ + E+ K E E+ +
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 226 PPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVM 285
E+K + + ++ K E+ K++E E + + HE ++ + M
Sbjct: 622 Q--EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKM 679
Query: 286 RKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQ 345
+++ +++ +K +EQ+ + W+++ R E + R + E K RE E
Sbjct: 680 QEQEEKIWEQEKMEKKTQEQE--------KKTWDQEKMREEESMRER--EKKMREEEEMM 729
Query: 346 FPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPP 405
+ K +EQ+E+ Q E E+ E + + EQE + ++L
Sbjct: 730 REQEEKMQEQEEKMQE--------------QEEEMWEQEEKMWEQEEKMWEQQRLPEQKE 775
Query: 406 MMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASY 465
+++ E+ M++ K+++ + M D E+++ Q K G
Sbjct: 776 KLWEHEK-----------MQEQEKIWEQEEKMR---DQEEKMRG----QEEKMRG----- 812
Query: 466 LERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGR-NQQIARPSQEEKVEEKEEDKAEK 524
+ E + + +G+ Q+ QEEK+ +EE EK
Sbjct: 813 -----------------QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEK 855
Query: 525 TEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEE 560
+ +EE+ +++EEK ++ K +E +K+ G E+
Sbjct: 856 MQGQEEKMREQEEKMRGQEEKMREQE-EKMRGQEEK 890
Score = 49.7 bits (117), Expect = 4e-05
Identities = 96/440 (21%), Positives = 192/440 (43%), Gaps = 42/440 (9%)
Query: 175 KLSKEELIQSMDRVDREIAKVEQQILKLKKK---QQQLEEEAAKPPEPEKPVSPPPV--- 228
K+ +EE ++M + ++ K E+ + + ++K QQ+L E+ K E EK
Sbjct: 458 KMREEE--ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 515
Query: 229 -EQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENI--KTNQVM 285
E+K R ++ E + +E + E + E + +Q E + KT +
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE 575
Query: 286 RKKLILFFKRRNHAR-KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAK----ESKTRE 340
+K K R R ++RE+K+ + + + E EK ++ E ++ K E K +E
Sbjct: 576 KKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQE 635
Query: 341 YYEKQFPEIRKQREQQERF---QRVGQRGAGLSATIARSEHE-ISEIIDGLSEQENNEKQ 396
EK + + K EQ+E+ QR+ ++ L E E + E + + EQE EK+
Sbjct: 636 QEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKK 695
Query: 397 MRQLSVIPPMMFDAEQRRVKFI---NMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFI 453
++ +D E+ R + + E+ + + + M + +E ++ +
Sbjct: 696 TQEQE---KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE 752
Query: 454 QHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKAL------VRRNYGKRRGRNQQIAR 507
Q K + E++ +P+ + +K + + + +R K RG+ +++
Sbjct: 753 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR- 811
Query: 508 PSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSK---ENTKEKDKIDGTAEETEER 564
QEEK+ +E EK +EE+ +EEK ++ K + K ++K+ G E+ E+
Sbjct: 812 -GQEEKMRGQE----EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ 866
Query: 565 EQATPRGRKTANSQGRRKGR 584
E+ RG++ + K R
Sbjct: 867 EEKM-RGQEEKMREQEEKMR 885
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 63.5 bits (153), Expect = 2e-09
Identities = 413/2087 (19%), Positives = 680/2087 (32%), Gaps = 373/2087 (17%)
Query: 498 RRGRNQQIARPSQE----EKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDS-KENTKEKD 552
RR + RP+ + E+ E E E EE+ +E++ EK + + EKD
Sbjct: 43 RRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Query: 553 KIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSM---TNEAAAASAAAAAATEEPPP 609
G EET + A + A ++ R+ + + +S E
Sbjct: 103 VNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQ 162
Query: 610 PLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNY 669
P P PP+P S +S + + KK + GR + + K ++ K
Sbjct: 163 PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKK------ 216
Query: 670 KRRHNLDNLLQQHKQKTSRKPREERDVSQCESVAST-----------VSAQEDEDIEASN 718
K R ++ ++H+ T + R+ +D + S ++T SA + S
Sbjct: 217 KHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSR 276
Query: 719 EEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEP-TTETAPSTSPSLAVPS-TKPAE 776
++ + SP A+ R A EP TT T +SP A + P E
Sbjct: 277 SRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYE 336
Query: 777 DESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKV 836
D+ D D++E SA P P+ + S E P ++
Sbjct: 337 DK------------------DKDKKEKSATR-----PSPSPERSSTGPEPPAPTPLLAER 373
Query: 837 EGDNTKE-RDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPER 895
G + + + E V P E + + PE + SS +
Sbjct: 374 HGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRH 433
Query: 896 QRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVS 955
P KP+ + + SSP N H A S TP
Sbjct: 434 ASSSPESPKPAPAPGSHREISSSPTSKN------RSHGRAKRDKSHSHTP---------- 477
Query: 956 GYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWEVLQPAPHQVI 1015
R + A + R R + + G S+S + +W + A
Sbjct: 478 -----SRRMGRSRSPATAKRGRSRSR--------TPTKRGHSRSRSPQWRRSRSAQRWGR 524
Query: 1016 TNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYT 1075
+ P+ R P P S+ T + G +P T S ++
Sbjct: 525 SRSPQ----RRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSR---- 576
Query: 1076 QETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVV--- 1132
TP S S R++ +++ T + + R ++ R++ V
Sbjct: 577 --TPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRR 634
Query: 1133 -RGTAGAIQEGSITRGTPTSK-ISVESIPSLRGSITQGTPALPQTGIPTEALVKGSISRM 1190
R + A + G TP + S P+ RG TPA + + SR
Sbjct: 635 SRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSR- 693
Query: 1191 PIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLKRSYESV 1250
+P +GR + S ++ G+S S + R G+ S R + +R S
Sbjct: 694 ---SRTPRRGRSRSRS---LVRRGRSH---SRTPQRRGRSGSSSERKNKSRTSQRRSRS- 743
Query: 1251 EGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFED 1310
M++S +S+ R+ SP S K R L S+ +P
Sbjct: 744 ----NSSPEMKKSRISSR------RSRSLSSPRSKAKSRLSLRRSLSGSSP--------- 784
Query: 1311 GLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQESRKT--- 1367
PKQ K ++PP R+ G+ +P T RS P + SR++
Sbjct: 785 ---CPKQ-KSQTPPRRSRSGS---SQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837
Query: 1368 ----PEVVQSTRPIIEGSISQG-------TPIKFDNNSGQSAIKHNVKSLITGPSKLSRG 1416
P+V T P +GSI+ TP + + +S+ +KS S
Sbjct: 838 SSPHPKVKSGTPP-RQGSITSPQANEQSVTPQR--RSCFESSPDPELKSRTPSRHSCSGS 894
Query: 1417 MPP---LEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSP 1473
PP P VKA + R R S SS PS R T P+ S
Sbjct: 895 SPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHS-GSSSPSPSRVTSRTTPRRSRSV 953
Query: 1474 GIYDDTSARRTP-VSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAK 1532
+ +R P S+ + S + + T S + + + TP +K
Sbjct: 954 SPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSK 1013
Query: 1533 SPVP---GVDPVVSHSPFDPH-----HRGSTAGEVY-----------RSHLPTH-LDPAM 1572
SP P D +V P + GE Y P H D +
Sbjct: 1014 SPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSS 1073
Query: 1573 PFHRALDPAAAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVA 1632
P R + + + Q SP G +R I D + + + P +
Sbjct: 1074 PEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQD-----RGEFSASPMLK 1128
Query: 1633 RGLSP---REQPLGLPYPA--TRGIIDLTNMPPT------ILVPHPGGTSTPPMDRITYI 1681
G+SP R Q YP + ++ + + L P T++PP + +
Sbjct: 1129 SGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFS 1188
Query: 1682 -------PGTQITF------PPRPYNSASMSPGHPTHLAAAASAERERER----EREKER 1724
P + + F PPR + A SP +A ++ ++ E E+ +E
Sbjct: 1189 PFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEP 1248
Query: 1725 ERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQ------QRPSVFQGT 1778
+ ++ SS+L S P P+ S+ ++ Q + PS+
Sbjct: 1249 AGQILSHLSSELKEMSTSNFESSPEVE---ERPAVSLTLDQSQSQASLEAVEVPSMASSW 1305
Query: 1779 NGTSVI--------TPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAAS 1830
G +PL + + GP ++ D ++ +
Sbjct: 1306 GGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLET 1365
Query: 1831 APQMDVSK--TKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFP 1888
P +D+ + T+ S H ++ L + + A +S Q + L+ R+ +SSA
Sbjct: 1366 DPSLDMKEQSTRSSGHSSSELSPDAVEK-AGMSSNQSISSPVLDAVPRTPSRERSSSASS 1424
Query: 1889 --------------------------SGKPQPHSSVVYSEAGK-------------DKGP 1909
SG P HS S K D P
Sbjct: 1425 PEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSP 1484
Query: 1910 PPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARER-GSQSSDSSSSLS----SH 1964
PK+ + R R ++ ++ + +T Q RER GS+SS +++
Sbjct: 1485 EPKA-LPQTPRPRSRSP-SSPELNNKCLTPQ-------RERSGSESSVDQKTVARTPLGQ 1535
Query: 1965 RYETPSDAIEVISPASSP-------APPQEKLQTYQPEVVKANQAEN---------DPTR 2008
R + S + P++SP + P K +T P ++ + P R
Sbjct: 1536 RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRR 1595
Query: 2009 QYEGPLHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQV 2068
G + + + +P+ Q S E PR R++
Sbjct: 1596 SRSGSSPEVKDKPRA-APRAQSGSDSSPEPKAPAPRALP----------------RRSRS 1638
Query: 2069 SSQTPQQPPTSTFQNSPSALVSTPVRTKTS---NRYSPESQAQS-VHHQRPGSRVSPENL 2124
S + + P+ +S + P +++T+ +R SPE + +S +R SR SPE L
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPE-L 1697
Query: 2125 VDKSRGSRPGKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARS 2184
K+R SR +S S P + + P H + S+ EPAE+ +R
Sbjct: 1698 TRKARLSRRSRSASSS--------PETRSRTPPRHRRSPSV-----SSPEPAEKSRSSRR 1744
Query: 2185 PGSISYLPSFFTKLENTSPMVKSK------------KQEIFRKLNSSGGGDSDMAAAQPG 2232
S S + T SP K + K R+ + SG S Q
Sbjct: 1745 RRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS 1804
Query: 2233 TEIFNLPAVTTSGSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGV 2292
+ GS G+ PA R+ G + P
Sbjct: 1805 RSRSRVTRRRRGGS----GYHSRSPARQESSRTSSRRR-----------RGRSRTPPTSR 1849
Query: 2293 VPGTANTSVVTSGETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSS 2352
+ TS + R P+ H + LIS+ SR SP+ R S
Sbjct: 1850 KRSRSRTS-PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPV------SRRRSRS 1902
Query: 2353 VSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPT 2399
+SV R +P R S T P+T R S PT
Sbjct: 1903 RTSVTRRRSRSRASP----VSRRRSRSRTP----PVTRRRSRSRTPT 1941
Score = 53.9 bits (128), Expect = 2e-06
Identities = 139/601 (23%), Positives = 204/601 (33%), Gaps = 65/601 (10%)
Query: 1472 SPGIYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIP- 1530
SPG+ + + RTP+S G MM+ + QR S+P
Sbjct: 2132 SPGMLEPLGSSRTPMSV--LQQAGGSMMDGPGP---------------RIPDHQRTSVPE 2174
Query: 1531 --AKSPVPGVDPVVSHSPFDPHHRGSTAGEVYR-SHLPTHLDPAMPFHRALD-------P 1580
A+S + +S P S AG R S +P + P M A P
Sbjct: 2175 NHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPV-PLMSLRTAPAANLASRIP 2233
Query: 1581 AAAAYLFQRQLSPTPGYPSQYQLYAMEN----TRQTILNDYITSQQMQVNLRPDVARGLS 1636
AA+A + TP P+ L + + VNL D +
Sbjct: 2234 AASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLA-DPRTPTA 2292
Query: 1637 PREQPLGLPYPATRGIIDLTNM--PPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYN 1694
P G PA + LT PPT +P + TP + G + P N
Sbjct: 2293 PAVNLAGARTPAALAALSLTGSGTPPTA-ANYPSSSRTPQAPASANLVGPRSAHATAPVN 2351
Query: 1695 ------SASMSPGHPTHLAAA-ASAEREREREREKERERERIAAASSDLYL-RPGSEQPG 1746
+A+++P T A A + R ER++ +S L R S P
Sbjct: 2352 IAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPP 2411
Query: 1747 RPGSHGYV---RSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLP--AG 1801
S + R+PSPS R + Q Q + V + ++ I AG
Sbjct: 2412 SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471
Query: 1802 GPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKESK-----HEAARLEENLRSR 1856
S+S G A+ ++A D L A P DV + S A L+ R
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERR 2531
Query: 1857 SAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYE 1916
S++ S + S +SS+ G P V E + P P +
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP----VQPEVALKRVPSPTPAPK 2587
Query: 1917 EELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDAIEVI 1976
E +R T A R +S + S SS SSSS SS + S +
Sbjct: 2588 EAVREGRPPEPTPAKRK----RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Query: 1977 SPASSPAPPQEKLQTY-QPEVVKANQAENDPTRQYEGPLHHYRPQQE-SPSPQQQLPPSS 2034
S +SSP+P + Q +P K +R P+ R + S SP ++ PS
Sbjct: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703
Query: 2035 Q 2035
Q
Sbjct: 2704 Q 2704
Score = 47.0 bits (110), Expect = 2e-04
Identities = 156/754 (20%), Positives = 259/754 (34%), Gaps = 125/754 (16%)
Query: 1480 SARRTPVSYQN--TMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPG 1537
S RTP + + +++R P + R S SS++S +S P R +++P
Sbjct: 2054 SRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRS-----RSATPPATRNHSGSRTPPVA 2108
Query: 1538 VD---------PVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQ 1588
++ P +S +P D R P L+P + A
Sbjct: 2109 LNSSRMSCFSRPSMSPTPLD------------RCRSPGMLEPLGSSRTPMSVLQQAGGSM 2156
Query: 1589 RQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDV--ARGLSPREQPLGLPY 1646
P P P + EN Q+ + +T+ + P A GL+ R + P
Sbjct: 2157 MD-GPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPV 2215
Query: 1647 PATRGIIDLTNMPPTILVPHPGGTSTPPMD----RITYIP-GTQITFPPRPYNSASMSPG 1701
P ++ L P L S M+ R IP + P +A+M+
Sbjct: 2216 P----LMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLA 2271
Query: 1702 HPTHLAAAASAEREREREREKERER---ERIAAASSDLYLRPGSEQPGRPGSHGYVRSP- 1757
P A ++ R R AA + L L P R+P
Sbjct: 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQ 2331
Query: 1758 ---SPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRY 1814
S ++ + P G+ + + P T+ R+ P +G S +P S Y
Sbjct: 2332 APASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSA-RMAPALSGANLTSPRVPLSAY 2390
Query: 1815 NTAADALAA-LVDAAAS-----APQMDVSKTKESKHEAARLEENLRSRSAAVSEQQQLEQ 1868
+ + L+D A S AP ++ + ++R+ + S+S Q Q
Sbjct: 2391 ERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQ-APSQSLLPPAQDQPRS 2449
Query: 1869 KTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVY---SEAGKDKG----PPPKSRYEEELRT 1921
+CL + +G S V S AG G P P + +
Sbjct: 2450 PVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP 2509
Query: 1922 RGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDAIEVISPASS 1981
T + +A+ + A+ER S SS SSSS SS + S + S SS
Sbjct: 2510 PASTGAQQPS--------ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS--SSGSS 2559
Query: 1982 PAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMGQ 2041
+ + QPEV A + PT + + RP + +P+ +++
Sbjct: 2560 SSDSEGSSLPVQPEV--ALKRVPSPTPAPKEAVREGRPPEPTPAKRKR------------ 2605
Query: 2042 VPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNRY 2101
+ SS + +S+ +S S+ S+ + +S+
Sbjct: 2606 -------------------------RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 2102 SPESQAQSVHHQRPGSRVSPENLVDKSR--GSRPGKSPER--------SHVSSEPYEPIS 2151
S S + S +PG + P+ K G R +SP + +S P E
Sbjct: 2641 SSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR 2700
Query: 2152 PPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSP 2185
P P ++Q S S+RG+ QR D+RSP
Sbjct: 2701 PSPQPSPRDQQSS---SSERGSRRG-QRGDSRSP 2730
Score = 46.2 bits (108), Expect = 4e-04
Identities = 362/1826 (19%), Positives = 588/1826 (32%), Gaps = 272/1826 (14%)
Query: 711 DEDIEASNEEENPEDSEVEAVKP-SEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAV 769
D + S+ E SE +++ S+ SP+ SR ++ P EL + A
Sbjct: 1066 DHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSS-PVTELASRSPIRQDRGEFSAS 1124
Query: 770 PSTKPAEDESVETQVNDSISAETAEQMDVDQQEH--SAEEGSVCDPPPATKADSVDVEVR 827
P K +DS S T + + Q +AE PP + D+ R
Sbjct: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPP--QEDATASPPR 1182
Query: 828 VPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADE 887
+ + D + + + + + PR+ PE + N + T S DE
Sbjct: 1183 QKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGA------GSSPETKEQNSALPTSSQDE 1236
Query: 888 DVDGEPERQRMFPMDSKPSLLNPTGSIL--VSSPLKP----NPLDLPQLQHRAAVIPPM- 940
++ E+ P G IL +SS LK N P+++ R AV +
Sbjct: 1237 ELMEVVEKSE-----------EPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLD 1285
Query: 941 VSCTPCNIP-IGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKS 999
S + ++ + P + H H+ R+ LE R+S P GT +
Sbjct: 1286 QSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNS-GPLGTEMN 1344
Query: 1000 PNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQ 1059
EV + + L L + S + A EK G S +Q
Sbjct: 1345 TGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKA----GMSSNQ 1400
Query: 1060 GTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQ-QESAKSATLPYIKQEEFSP--RSQN 1116
L + + + + S + GLPR ++S + P ++ +P S +
Sbjct: 1401 SISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLS 1460
Query: 1117 SQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTG 1176
G+ + R + E TP + S P L TP ++G
Sbjct: 1461 GSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCL--TPQRERSG 1518
Query: 1177 IPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPR 1236
+ K +++R P+ S +E K + +S D+ +++ TR+P
Sbjct: 1519 SESSVDQK-TVARTPLGQRSRSGSSQELDVKPSASPQERS----ESDSSPDSKAKTRTPL 1573
Query: 1237 TAHEISLKRSYESVEGNIKQGMSMRESPV-SAPLEGLICRALPRGSPHSDLKE------- 1288
RS S E + K +S R S S+P RA PR SD
Sbjct: 1574 RQRS----RSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAP 1629
Query: 1289 ----RTVLSGSIMQG---TPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGI 1341
R SGS +G +P ++ S E ++P + + R+ TK +
Sbjct: 1630 RALPRRSRSGSSSKGRGPSPEGSS-STESSPEHPPKSRTARRGSRSSPEPKTKSRT---- 1684
Query: 1342 TTIKEMGRSIHEIPRQDILTQESRK---TPEVVQSTRPIIEGSISQGTPIKFDNNSG--- 1395
+ RS E+ R+ L++ SR +PE T P S S +P + +
Sbjct: 1685 PPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR 1744
Query: 1396 -QSAIKHNVKSLIT---GPSKLSRGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSV 1451
+SA K+ PS RG+ K + D SR
Sbjct: 1745 RRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT-RTTRRRDRSGSSQSTSRRRQR 1803
Query: 1452 VSSGPSVLRSTLHEAPKAQLSPGIYDD--TSARRT-------PVSYQNTMSRGSPMMNRT 1502
S V R + SP + TS+RR P S + + SR SP +
Sbjct: 1804 SRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKR 1863
Query: 1503 SDVTISSNKSTNHERKSTLTP--TQRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVY 1560
S S H R + TP ++R S SPV R + V
Sbjct: 1864 SR---SRASPATHRRSRSRTPLISRRRSRSRTSPVS-------------RRRSRSRTSVT 1907
Query: 1561 RSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITS 1620
R + P R +PT S+ + + R +T
Sbjct: 1908 RRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTR 1967
Query: 1621 QQMQVNLRPDVARGLSPREQPL------GLPYPATRGIIDLTNMPPTILVPHPGGTSTPP 1674
++ + P R R P+ P TR P T + TPP
Sbjct: 1968 RRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVT---RRRSRSRTPP 2024
Query: 1675 MDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKERERERIAAASS 1734
R T + R + + ++ + +A +R R R R A+ SS
Sbjct: 2025 AIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSS 2084
Query: 1735 DLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLR 1794
R S P +H R+P ++ + RPS+ TPLD
Sbjct: 2085 SD--RSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSP--------TPLDRCRS-- 2132
Query: 1795 IMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKESKHEAARLEENLR 1854
P + + L +SR ++ L A S MD + H+ + EN
Sbjct: 2133 --------PGMLEPLGSSR-----TPMSVLQQAGGS--MMDGPGPRIPDHQRTSVPENHA 2177
Query: 1855 SRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPKSR 1914
A++ T+ + + +P P S A + P P
Sbjct: 2178 QSRIALA--------------------LTAISLGTARPPPSMSAAGLAARMSQVPAP--- 2214
Query: 1915 YEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDAIE 1974
+ T AAN I A+ A R + + ++ +L+ R + A+
Sbjct: 2215 ----VPLMSLRTAPAANLASRIPAASAAAMNLASAR-TPAIPTAVNLADSRTPAAAAAMN 2269
Query: 1975 VISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQQQLPPSS 2034
+ SP ++ AP L + A T P+ L
Sbjct: 2270 LASPRTAVAPSAVNLADPRTPTAPAVNLAGART----------------PAALAAL---- 2309
Query: 2035 QAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVR 2094
G G P A SS+TPQ P ++ SA + PV
Sbjct: 2310 SLTGSGTPPTA------------------ANYPSSSRTPQAPASANLVGPRSAHATAPVN 2351
Query: 2095 -------------TKTSNRYSPESQAQSV--------HHQRPGSRVSPENLVDKSRGSRP 2133
+ TS R +P ++ ++R R SP L+D++R P
Sbjct: 2352 IAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPP-LLDRARSRTP 2410
Query: 2134 GKSPERSHVSSE------------PYEPISPP-------QVPVVHEKQDSLLLLSQRGAE 2174
+P +S ++SE P + + PP VP Q L+
Sbjct: 2411 PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVA 2470
Query: 2175 PAEQRNDARSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSGGGD-SDMAAAQPGT 2233
++ + + S L +P V ++ S+G S +AA QP
Sbjct: 2471 GSQSLSSGAVATTTSSAGDHNGMLSVPAPGV--PHSDVGEPPASTGAQQPSALAALQPAK 2528
Query: 2234 EIFNLPAVTTSGSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVV 2293
E + + ++S S SS S + +S+ G S D + V + V
Sbjct: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSG---------SSSSDSEGSSLPVQPEVALKRV 2579
Query: 2294 PGTANTSVVTSGETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSV 2353
P + E RE P P + S S+S S S + SS
Sbjct: 2580 P----SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635
Query: 2354 SSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAP 2413
SS S +P A + P + P P S +P PI ++ +
Sbjct: 2636 SSSSSSSSSSSSSPSPA-KPGPQALPKPASPKKPPPGERRSRSPRKPI----DSLRDSRS 2690
Query: 2414 HQQNRIWEREPAPLLSAQYETLSDSD 2439
+ + R P+P S + + S S+
Sbjct: 2691 LSYSPVERRRPSPQPSPRDQQSSSSE 2716
Score = 44.3 bits (103), Expect = 0.001
Identities = 134/689 (19%), Positives = 233/689 (33%), Gaps = 97/689 (14%)
Query: 497 KRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDG 556
+RRGR++ R + +T + + + S+ T+ + +
Sbjct: 549 QRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRT 608
Query: 557 TAEETEEREQATPRGRKTANSQGRRKGRI---------TRSMTNEAAAASAAAAAATEEP 607
A R + R R S RR+ R +RS T S + A
Sbjct: 609 PARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR 668
Query: 608 PPPLPPPPEPISTEPVETSRWTEEEMEVAKKG------LVEHGRNWAAIAKMVG-TKSEA 660
P + +R ++G LV GR+ + + G + S +
Sbjct: 669 SRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSS 728
Query: 661 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVAST-----VSAQEDEDIE 715
+ KN +RR ++ + K + S R R +S S A + S
Sbjct: 729 ERKNKSRTSQRRSRSNSSPEMKKSRIS--SRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP 786
Query: 716 ASNEEENPEDSEVEAVKP---SEDSPENATSRGNTEPAVELE-PTTETAPSTSPSLAVPS 771
+ P S + +P S P + S + P + + P+ ++ S+SP V S
Sbjct: 787 KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS 846
Query: 772 TKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPEN 831
P SI++ A + V Q S E S P P K+ R P
Sbjct: 847 GTPPR--------QGSITSPQANEQSVTPQRRSCFESS---PDPELKS-------RTPSR 888
Query: 832 HASKVEG-----DNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSAD 886
H+ +T R S +P+ + ++ P +S + SS+ +
Sbjct: 889 HSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAII--------SPRQRSHSGSSSPSPSR 940
Query: 887 EDVDGEPERQR-MFPMDSKPSLLNPTGSILVSS--PLKPNPLDLPQLQHRAAV------- 936
P R R + P + S L P S SS K P P+ H ++
Sbjct: 941 VTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVK 1000
Query: 937 --IPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQE------QIDLECR 988
PP S + P S +L Q ++ A ++ E + L+ +
Sbjct: 1001 AQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQ 1060
Query: 989 SSTSP---CGTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVA 1045
S TSP TS R+ P+ P+G R +R + P L +S++ +
Sbjct: 1061 SQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGR---SRSSSPVTEL--ASRSPIR 1115
Query: 1046 SEKPSFIMGGSISQG----------TPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQE 1095
++ F + G +Y T + + Q + + + LP Q++
Sbjct: 1116 QDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQED 1175
Query: 1096 SAKSATLPYIKQEEFSPRSQNSQPEGLLV 1124
+ S P ++++FSP +PE LV
Sbjct: 1176 ATAS---PPRQKDKFSPFPVQDRPESSLV 1201
Score = 35.0 bits (79), Expect = 0.90
Identities = 52/291 (17%), Positives = 103/291 (35%), Gaps = 48/291 (16%)
Query: 481 TKKNENYKALVRRNYGKRR--GRNQQI-ARPS---QEEKVEEKEEDKAEKTEKKEEEKKD 534
++ + + K + R G+R G +Q++ +PS QE + D KT ++
Sbjct: 1519 SESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSR 1578
Query: 535 EEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAA 594
E DSK + G++ E +++ +A PR + ++S K R++ +
Sbjct: 1579 SGSSPEV-DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSR 1637
Query: 595 AASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMV 654
+ S++ P P + E+S + A++G + +
Sbjct: 1638 SGSSSKGRG-----------PSPEGSSSTESSPEHPPKSRTARRG--------SRSSPEP 1678
Query: 655 GTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDI 714
TKS +RR + + K + SR+ R SA +
Sbjct: 1679 KTKSRTP-------PRRRSSRSSPELTRKARLSRRSR---------------SASSSPET 1716
Query: 715 EASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSP 765
+ + V + +P+E S + R + P + +PS P
Sbjct: 1717 RSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKP 1767
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 63.2 bits (152), Expect = 3e-09
Identities = 90/390 (23%), Positives = 143/390 (36%), Gaps = 54/390 (13%)
Query: 518 EEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANS 577
+ D AE E E E + + E + E + +G A+E E Q + +
Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVE--------APEAEGDAQEAEGEAQPESEDVEAPEA 1879
Query: 578 QGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAK 637
+G + T EA + E P PE S E +ET E E E A+
Sbjct: 1880 EGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAE 1939
Query: 638 KGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVS 697
A A+ ++E Q + +++ + + +P E DV
Sbjct: 1940 ----------AQEAEEAAQEAEGQTQ----------PESEVIESQEAEEEAQP-ESEDVE 1978
Query: 698 QCESVASTVSAQ-----EDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVE 752
E T A+ E ED+EA E +++E EA +P D E A + E A E
Sbjct: 1979 ALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEA-QPESDGVE-AQPKSEGEEAQE 2036
Query: 753 LE-PTTETAPSTSPSLAVPSTKPAEDES--VETQVNDSISAETAEQMDVDQQEHSAEEGS 809
+E T +T P AE+E+ E +V ++ E DVD QE E
Sbjct: 2037 VEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGE--- 2093
Query: 810 VCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLD-----RASEKVEPRDEDLVVAQ 864
+ +S VE E A K EG E + + E E E ++
Sbjct: 2094 -------AQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE 2146
Query: 865 QINAQRPEPQSDNDSSATCSADEDVDGEPE 894
+ AQ E ++ +S + + + + +PE
Sbjct: 2147 GVEAQDAEGEAQPESEGIEAQEAEEEAQPE 2176
Score = 50.8 bits (120), Expect = 2e-05
Identities = 89/431 (20%), Positives = 159/431 (36%), Gaps = 41/431 (9%)
Query: 496 GKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKED------------ 543
G+ + ++ + P E +E E + ++E E + + E + E ED
Sbjct: 1842 GEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQP 1901
Query: 544 SKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAA 603
E + + ETE E G S+G + + EA + +
Sbjct: 1902 ESEGAEAPEAEKEAQPETESVEALETEGEDEPESEG-AEAQEAEEAAQEAEGQTQPESEV 1960
Query: 604 TEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCK 663
E PE E +E T +E E + E A +M + EAQ +
Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVET-QEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPE 2019
Query: 664 NFYFNYKRRHNLDNL--LQQHKQKTSRKPREERDVSQCESVASTVSAQEDE-DIEASNEE 720
+ + + + ++ QKT + E D E+ + AQE E +++ + E
Sbjct: 2020 SDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESD--GVEAPEAEEEAQEAEGEVQEAEGE 2077
Query: 721 ENPEDSEVEA------VKPSEDSPENATSRGNTEPAVELE-PTTE-TAPSTSPSLAVPST 772
+PE +V+A +P + E + G + A +E P TE A S + P
Sbjct: 2078 AHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEA 2137
Query: 773 K---PAEDESVETQVNDSISAETAEQMDVDQQEHSAE-EGSVCDPPPA---TKADSVDVE 825
+ E E VE Q + + +E ++ + E A+ E + P A + +S +E
Sbjct: 2138 EGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIE 2197
Query: 826 VRVPENHAS-KVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCS 884
E A ++EG E A E+ +P E + + +PE + + S
Sbjct: 2198 APEAEGEAQPELEGVEAPE-----AEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGS 2252
Query: 885 ADEDV-DGEPE 894
+ DG+ E
Sbjct: 2253 PQVSLGDGQSE 2263
Score = 41.2 bits (95), Expect = 0.013
Identities = 72/351 (20%), Positives = 128/351 (36%), Gaps = 40/351 (11%)
Query: 496 GKRRGRNQQIARPSQEEKVEEKEED-------------KAEKTEKKEEEKKDEEEKDEKE 542
G+ + ++ I EE+ + + ED + E + E+ + E E + +E
Sbjct: 1952 GQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQE 2011
Query: 543 DSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAA 602
+E E D ++ A+ E E+A +T ++G + EA + A
Sbjct: 2012 AEEEAQPESDGVE--AQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEG 2069
Query: 603 ATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQC 662
+E P E + + E E E A + E A + T+ EAQ
Sbjct: 2070 EVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPE--AEGEAQKAEGIEAPETEGEAQP 2127
Query: 663 KNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDV-SQCESVASTVSAQEDEDIEASNEEE 721
++ ++ + + + + E +D + + + + AQE E+ EA E E
Sbjct: 2128 ES--------EGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEE-EAQPELE 2178
Query: 722 NPEDSEVEA-VKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESV 780
E E E +P + E + G +P +E E P T AE E+
Sbjct: 2179 GVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQ 2238
Query: 781 -----ETQVNDSISAETAEQMDVDQQEHSAEEGSVC-----DPPPATKADS 821
ETQ S + + + Q E ++E S PPP+ D+
Sbjct: 2239 PESEGETQGEKKGSPQVS--LGDGQSEEASESSSPVPEDRPTPPPSPGGDT 2287
Score = 40.0 bits (92), Expect = 0.028
Identities = 69/346 (19%), Positives = 124/346 (35%), Gaps = 62/346 (17%)
Query: 1826 DAAASAPQMDVSKTKESKHEAARLEENLRSRSAAVS------EQQQLEQKTLEVEKRS-V 1878
D + P+ + + +E + E + E + + S V E Q+ E + E E +
Sbjct: 2021 DGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHP 2080
Query: 1879 QCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIIT 1938
+ + G+ QP S V EA + +G K+ E T G+ +
Sbjct: 2081 ESEDVDAQEAEGEAQPESEGV--EAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAE 2138
Query: 1939 RQIASDKD---ARERGSQSSDSSSSLSSHRYETPS----DAIEVISPASSPAPPQEKLQT 1991
+ + + A++ ++ S + + E + + +E P E ++
Sbjct: 2139 GEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEA 2198
Query: 1992 ------YQPEV--VKANQAENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMGQVP 2043
QPE+ V+A +AE + + EG E+P + + P S+ E G+
Sbjct: 2199 PEAEGEAQPELEGVEAPEAEEEAQPEPEGV--------ETPEAEGEAQPESEGETQGEKK 2250
Query: 2044 RTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNRYSP 2103
+ + ++L D Q ++ SS P+ PT P
Sbjct: 2251 GSPQ-VSLGDG------QSEEASESSSPVPEDRPTP-----------------------P 2280
Query: 2104 ESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSSEPYEP 2149
S HQRPGS+ P + S G+ K E HV + P
Sbjct: 2281 PSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSP 2326
Score = 37.7 bits (86), Expect = 0.14
Identities = 46/220 (20%), Positives = 82/220 (37%), Gaps = 15/220 (6%)
Query: 679 LQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSP 738
L++ K+ T + +E V E+ +E +E + E E E EA +
Sbjct: 1303 LEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEA---QLEEI 1359
Query: 739 ENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETA----- 793
E G E V+LE E A+ E E V+ +E +
Sbjct: 1360 EETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGK 1419
Query: 794 --EQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASE 851
++ D Q+E + + +P PA + E P +H S+ + ++ + +
Sbjct: 1420 GSQEDDPVQEEEAGRASASAEPCPAEGTE----EPTEPPSHLSETDPSASERQSGSQLEP 1475
Query: 852 KVE-PRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVD 890
+E P ++ + AQ + ++ SS CSA D D
Sbjct: 1476 GLEKPPGATMMGQEHTQAQPTQGAAERSSSVACSAALDCD 1515
Score = 35.4 bits (80), Expect = 0.69
Identities = 101/540 (18%), Positives = 166/540 (30%), Gaps = 93/540 (17%)
Query: 1890 GKPQPHSSVVYSEAGKDKGPPPKSR-------YEEELRTRGKTTITAANFIDVIITRQIA 1942
GK + +S + G D P S + E + +G T A + ++
Sbjct: 557 GKARAETSQQEASEGGDPASPALSLSSLRSDDLQAETQGQGTEQATGAAVTREPLVLGLS 616
Query: 1943 SDKDARERGSQSSDSSSSLSSHR--------YETPSD-AIEVISPASSPAPPQEKLQTYQ 1993
D+ S S +SS R +PS + ++P P + T+
Sbjct: 617 CSWDSEGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVAPRGHPRHSHYRKDTHS 676
Query: 1994 PEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQQQLPPSS---QAEG------MGQVPR 2044
P ++ T+Q P R Q+ P+ SS QA G G +P
Sbjct: 677 P-------LDSSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPPSSGSLPS 729
Query: 2045 THRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTP--VRTKTSNRYS 2102
L T + + + DF VS +P P++ + + +P + TS+ S
Sbjct: 730 QDLLGTSSATVTPAVHSDF----VSGVSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDSCS 785
Query: 2103 PESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSSEP---------------- 2146
A R + S ++ R + P RSH S+P
Sbjct: 786 KSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGPSPEA 845
Query: 2147 ------YEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLEN 2200
Y P P P + S G+ + ++ AR PG P T+
Sbjct: 846 SWLCGRYCPTPPRGRPCPQRRSSSC------GSTGSSHQSTARGPGG---SPQEGTRQPG 896
Query: 2201 TSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASN 2260
+P R S G G ++ + T +G A S
Sbjct: 897 PTPSPGPNSGASRRSSASQGAGSRGLSEEK-----------TLRSGGGPQGQEEASGVSP 945
Query: 2261 LGLEDIIRKALMGSFDDKVEDHGVVMS-----QPMGVVPGTANTSVVTSGETRREEGDPS 2315
L +A++ + D + + ++M+ + G G V G+ EG
Sbjct: 946 SSLPRSSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGE 1005
Query: 2316 PHSGGVCK--------PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTP 2367
P G P+ P G+G P VS +E R+ P
Sbjct: 1006 PAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQGAAPEGVSEAPAEAGADREAP 1065
Score = 32.3 bits (72), Expect = 5.9
Identities = 38/146 (26%), Positives = 61/146 (41%), Gaps = 24/146 (16%)
Query: 510 QEEKVEEKEEDKAEKTEKKEEEKKDEEEKD-------EKEDSKENTKE--KDKIDGTAEE 560
QEE V+ +E + E ++EEE + EE ++ E+ E KE + + G A E
Sbjct: 1332 QEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALE 1391
Query: 561 TEEREQATPRG--------RKTANSQGRRKGRITRSMTNEAAAASAAA----AAATEEPP 608
+E+ P + ++ G+ EA ASA+A A TEE
Sbjct: 1392 EGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEE-- 1449
Query: 609 PPLPPPPEPISTEPVETSRWTEEEME 634
P PP T+P + R + ++E
Sbjct: 1450 -PTEPPSHLSETDPSASERQSGSQLE 1474
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 63.2 bits (152), Expect = 3e-09
Identities = 107/470 (22%), Positives = 170/470 (36%), Gaps = 51/470 (10%)
Query: 679 LQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSP 738
L K K P Q ST +EDE+ +E E D + ++ P
Sbjct: 959 LPSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEE----SERERDRDMADTPCELAKRDP 1014
Query: 739 ENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAED--ESVETQVNDSISAETAEQM 796
+ R +EL+ E S S ST+ E+ E E + +D ++ ++
Sbjct: 1015 KGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDES 1074
Query: 797 DVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPR 856
+ D ++ + E S D + + ++V + E +S E + E + S
Sbjct: 1075 ENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSS-ESSESSEFESSSESSPSSSE 1133
Query: 857 DEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILV 916
DE+ VVA++ + E + + S + ED + + E + P G+ V
Sbjct: 1134 DEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAP-----------GAPAV 1182
Query: 917 SSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQ 976
S +D+ P M+ P + + P + + + LL +
Sbjct: 1183 DSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPE 1242
Query: 977 RQRQEQIDLECRSSTSPCGTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPL 1036
+E +E R SP ++P + EV +P P ++ LP LP RP RPP P
Sbjct: 1243 PPAKE---VEARPPLSP---ERAPEHDLEV-EPEPPMMLP-LPLQPPLPPPRPPRPPSP- 1293
Query: 1037 IPSSKTTVASEK--PSFIMGGSISQGTPGTYLTSHNQASYTQET--------PKPSVGSI 1086
P +TT AS P + TPG L S + ET P S GS
Sbjct: 1294 PPEPETTDASHPSVPPEPLAEDHPPHTPG--LCGSLAKSQSTETVPATPGGEPPLSGGSS 1351
Query: 1087 SLGL------------PRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLV 1124
L L P S S LP +FS S+P G L+
Sbjct: 1352 GLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLL 1401
Score = 48.9 bits (115), Expect = 6e-05
Identities = 71/320 (22%), Positives = 127/320 (39%), Gaps = 40/320 (12%)
Query: 497 KRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKE-NTKEKDKID 555
+R R ++ +E++ E E++ E++E E+++EEE D+ +DS + + E D D
Sbjct: 1021 RRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDED 1080
Query: 556 GTAEETEEREQATPRGRKTAN---SQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLP 612
E E+++ +T + S+ S ++E ++S ++ +++E+ +
Sbjct: 1081 TALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVA 1140
Query: 613 PPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIA------KMVGTKSEAQCKNFY 666
E E E EE M A E AA+A +G + E +
Sbjct: 1141 REEE---EEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEA 1197
Query: 667 FNYKRRHNLDN----LLQQHKQKTSRKPREERDVSQ--CESVASTVSAQEDEDIEASNEE 720
+ R ++ + + + SR+P EE +SQ ++ A+E E + E
Sbjct: 1198 VAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPE 1257
Query: 721 ENPE-DSEVE-------------------AVKPSEDSPENATSRGNTEPAVELEPTTETA 760
PE D EVE +P PE T+ + P+V EP E
Sbjct: 1258 RAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDA-SHPSVPPEPLAEDH 1316
Query: 761 PSTSPSLAVPSTKPAEDESV 780
P +P L K E+V
Sbjct: 1317 PPHTPGLCGSLAKSQSTETV 1336
Score = 35.4 bits (80), Expect = 0.69
Identities = 40/180 (22%), Positives = 72/180 (40%), Gaps = 19/180 (10%)
Query: 51 SQASQLLQQQQQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPR 110
S+ + + +++++ +++E S P++ E P DSL
Sbjct: 1132 SEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLG----- 1186
Query: 111 LEQVSDSHFQRVSAAVLPLV---HPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGD 167
+E+ D + V+ P + PLP G+ AD+++ P G + + +S +P
Sbjct: 1187 MEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAK 1246
Query: 168 DQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPP 227
+ A P LS E + D E+ +L L + PP P +P SPPP
Sbjct: 1247 EVEARP-PLSPERAPEH----DLEVEPEPPMMLPLPL------QPPLPPPRPPRPPSPPP 1295
Score = 33.1 bits (74), Expect = 3.4
Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 10/64 (15%)
Query: 602 AATEEPPPPLPP-PPEPISTEPVETSR---------WTEEEMEVAKKGLVEHGRNWAAIA 651
A PPPPLPP PP P PVE ++ W E + +G E + +A
Sbjct: 1534 AGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELA 1593
Query: 652 KMVG 655
K G
Sbjct: 1594 KSRG 1597
Score = 31.6 bits (70), Expect = 10.0
Identities = 49/220 (22%), Positives = 87/220 (39%), Gaps = 16/220 (7%)
Query: 1944 DKDARERGSQSSDSSSSLS--SHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQ 2001
D D R+ S++ D ++LS S + E SD E +S +S A ++ + +++
Sbjct: 1067 DSDDRDE-SENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESS- 1124
Query: 2002 AENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQA----EGMGQVPRTHRLITLADHICQ 2057
+E+ P+ + R ++E ++ + S A E Q L A +
Sbjct: 1125 SESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDS 1184
Query: 2058 IITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGS 2117
+ ++ + + P++ P S P + V +R PE S Q
Sbjct: 1185 LGMEEEVDIETEAVAPEERP-SMLDEPP---LPVGVEEPADSREPPEEPGLS---QEGAM 1237
Query: 2118 RVSPENLVDKSRGSRPGKSPERSHVSSEPYEPISPPQVPV 2157
+SPE K +RP SPER+ EP P +P+
Sbjct: 1238 LLSPEPPA-KEVEARPPLSPERAPEHDLEVEPEPPMMLPL 1276
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 62.4 bits (150), Expect = 5e-09
Identities = 116/657 (17%), Positives = 251/657 (38%), Gaps = 64/657 (9%)
Query: 179 EELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQI 238
EEL + D + E+ + +LKKK +L+E+ + + +S +Q+
Sbjct: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLR-------------LAESEKSEIQL 208
Query: 239 IYDENRKKAEEAHKIFEGLGPK-VELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRN 297
E ++K E A + + ++ ++ Q + + + I+ + + + +
Sbjct: 209 NVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE 268
Query: 298 HARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAK----ESKTREYYEKQFPEIRKQR 353
+++E+K+ +R ++ + EK++ E R + K E + +E EK + + K R
Sbjct: 269 GKMREQEEKM-RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327
Query: 354 EQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQR 413
EQ+E+ R +R + E ++ + + + EQ+ ++ + M++ E+
Sbjct: 328 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEE- 386
Query: 414 RVKFINMNGLMEDPMKVYKDRQFM------------NVWTDHEKEIFKDKFIQHPKNFGL 461
K + E K+ ++ + M N+W EKE + + + +
Sbjct: 387 --KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 444
Query: 462 IASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEE-- 519
E++ + E ++ + + + R Q+ QEEK+ ++E+
Sbjct: 445 QEKMQEQEE--KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 502
Query: 520 -DKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEER--EQATPRGRKTAN 576
D+ E+ +++E +++EE+ ++ +EK + + +E E++ +Q +
Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 577 SQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEE----E 632
+ +K R M E E + E + + E W +E E
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ--EEKMWEQEEKMWE 620
Query: 633 MEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHK----QKTSR 688
E K + W KM E + K + K R + + +Q + Q+
Sbjct: 621 QEEEDKMQEQEEMMWEQEEKM----QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 676
Query: 689 KPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTE 748
+ +EE+ Q E + ++ + +EE E + E + R E
Sbjct: 677 REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE 736
Query: 749 PAVELEPTTE---TAPSTSPSLAV------PSTKPAEDESVETQVNDSISAETAEQM 796
E P E + P PS + S +PA E+ E D+ +A+ Q+
Sbjct: 737 KMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQDNPTAQEIMQL 793
Score = 60.8 bits (146), Expect = 2e-08
Identities = 77/395 (19%), Positives = 174/395 (44%), Gaps = 42/395 (10%)
Query: 178 KEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQ 237
+E+ ++ ++ RE K ++ KL+++++Q++E+ K E E+ + E+K +
Sbjct: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ--EEKMWRQEE 338
Query: 238 IIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRN 297
++++ ++ E+ K+ + E ++ Q + E ++ + M ++ K +
Sbjct: 339 RLWEQEKQMREQEQKMRDQ-----EERMWEQDERLREKEERMREQEKMWEQEE---KMQE 390
Query: 298 HARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQE 357
R + +K + ++ M E+K+ + E N E + +E+ +++ PE +++ +QE
Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEEN----MWEQEEKEWQQQRLPEQKEKLWEQE 446
Query: 358 RFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKF 417
+ Q ++ I R + E+ + QE +Q Q+ M D EQ+
Sbjct: 447 KMQEQEEKIWEQEEKI-RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Query: 418 INMNGLMEDPMKVYKDR--QFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 475
++ ++ ++R + +W EK + K + K
Sbjct: 506 EERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK----------------- 548
Query: 476 LYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEK--KEEEKK 533
+ E + R +++ R ++ QEEK++E+EE E+ EK ++EEK
Sbjct: 549 ----TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM 604
Query: 534 DEEEKD--EKEDSKENTKEKDKIDGTAEETEEREQ 566
E+E+ E+E+ +E+DK+ E E+E+
Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE 639
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 61.2 bits (147), Expect = 1e-08
Identities = 95/488 (19%), Positives = 194/488 (39%), Gaps = 87/488 (17%)
Query: 480 LTKKNENYKALVRRNYGKRRGRNQQIARPSQEE---------------KVEEKEEDKAEK 524
L+K+ + +L + RRGR + R +QE +E+ + EK
Sbjct: 846 LSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEK 905
Query: 525 TEKKEEEKKDEEEK---DEKEDSKENTKE--KDKIDGTAEETEEREQATPRGRKTANSQG 579
+E +E+ + EE+ E++ S++ + K ++ E + + +P K ++G
Sbjct: 906 SEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEG 965
Query: 580 RRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKG 639
+ S + A + ++ EE P PI T+P T + + + ++
Sbjct: 966 SERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKP--TLKRKKPFLHRRRRV 1023
Query: 640 LVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRR--------HNLDNLLQQHKQKTSRKPR 691
N + + + + +E + F + R +D ++ + + PR
Sbjct: 1024 RKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEE-EEEEDENELFPR 1082
Query: 692 E------ERDVSQCESVASTVSAQEDEDIEASNEEENP----------EDSEVEAVKPSE 735
E +DV +C+S + S E+ED E+ + ++ P D + ++P
Sbjct: 1083 EYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDT 1142
Query: 736 DSP---ENATSRGNTEPAV----------------ELEPTTETAPSTSPSLAVPST--KP 774
+P + +G + + E+ P + A P +++P KP
Sbjct: 1143 STPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKP 1202
Query: 775 ---AEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDP-----PPATKADSVDVEV 826
+E+VE + + + E E+ ++ + AEEG D P A+ ADS +
Sbjct: 1203 KIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSN--- 1259
Query: 827 RVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSAD 886
PE + E + +E+ R SE+ +E +Q + PEP+ + D++A + +
Sbjct: 1260 -SPETETKEPEVEEEEEK--PRVSEEQRQSEE-----EQQELEEPEPEEEEDAAAETAQN 1311
Query: 887 EDVDGEPE 894
+D D + E
Sbjct: 1312 DDHDADDE 1319
Score = 54.3 bits (129), Expect = 1e-06
Identities = 100/461 (21%), Positives = 174/461 (37%), Gaps = 81/461 (17%)
Query: 509 SQEEKVEEKEE----DKAEKTEKKEEEKKDEEEKDEKEDSKENTKEK------DKIDGTA 558
++E +VEE+EE + ++ ++E+++ +E E +E+ED+ T + D+ DG
Sbjct: 1265 TKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHL 1324
Query: 559 EETEERE-QATPRGRKTANSQGRRKGRITRSM--TNEAAAASAAAAAATEEPPPPLPPPP 615
E T+++E + P G ++ + +M + E +EE P
Sbjct: 1325 ESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQ---PSHD 1381
Query: 616 EPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNL 675
+ +E + S EE K+ L+E K E + + + + +
Sbjct: 1382 TSVVSEQMAGSEDDHEEDSHTKEELIE-------------LKEEEEIPHSELDLETVQAV 1428
Query: 676 DNLLQQHKQKTSRKPRE-ERDVSQCESVASTVSAQED------EDIEASNEEENPEDSEV 728
+L Q+ + ++ E ++ C+++ S A ED ED AS E N S V
Sbjct: 1429 QSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHAS--EHNSPISSV 1486
Query: 729 EAVKPSED----SPENATSRGNTEPAVELEPTTETAPS-----TSPSLAVPSTKPAEDES 779
++ PS+ S N + + + E + +APS TSP + VPS +
Sbjct: 1487 QS-HPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQV 1545
Query: 780 VETQVNDSISAE-TAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEG 838
V++ +D S E T E + S GS+C + + S G
Sbjct: 1546 VDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSY---------------G 1590
Query: 839 DNTKERDLDRASEKVEPRDEDLVVAQQINAQRPE----PQSDNDSSATCSADED----VD 890
+ L ++S VV QQ+ + QS +A CS V+
Sbjct: 1591 GLSSSSSLTQSS---------CVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVE 1641
Query: 891 GEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQ 931
P Q+ P P P +P P P PQ Q
Sbjct: 1642 RPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQ 1682
Score = 47.4 bits (111), Expect = 2e-04
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 11/184 (5%)
Query: 683 KQKTSRKP--REERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPEN 740
K++ RKP + R++ + A + + I + + ++SE E V+P ED P
Sbjct: 1164 KKRPGRKPGFKLSREIMPVSTQACVI--EPIVSIPKAGRKPKIQESE-ETVEPKEDMPLP 1220
Query: 741 ATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAE-DESVETQVNDSISAETAEQMDV- 798
+ E E E E + S VP+ PA+ S ET+ + E E+ V
Sbjct: 1221 EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVS 1280
Query: 799 DQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGD----NTKERDLDRASEKVE 854
++Q S EE + P + + E ++H + E D +TK+++L+ + +
Sbjct: 1281 EEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED 1340
Query: 855 PRDE 858
++E
Sbjct: 1341 VKEE 1344
Score = 36.6 bits (83), Expect = 0.31
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 6/80 (7%)
Query: 511 EEKVEEKEEDKAEKTEKKEEE------KKDEEEKDEKEDSKENTKEKDKIDGTAEETEER 564
EE+ EE EE + E+ + +E E K E E++ +++K ++ T
Sbjct: 788 EEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLS 847
Query: 565 EQATPRGRKTANSQGRRKGR 584
+Q P ANSQ R+GR
Sbjct: 848 KQVLPHDSLPANSQPSRRGR 867
Score = 31.6 bits (70), Expect = 10.0
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
Query: 1936 IITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDAIEVISPASS----PAPPQEKLQT 1991
++T+Q+AS + QSS ++ S ++P + P++ P PP ++ Q
Sbjct: 1604 VVTQQMASMGSSCSMMQQSSVQPAANCS--IKSPQSCVVERPPSNQQQQPPPPPPQQPQP 1661
Query: 1992 YQPEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQ-QQLPPSSQ 2035
P+ A Q P +Q +PQQ P P QQ PP SQ
Sbjct: 1662 PPPQPQPAPQPP--PPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQ 1704
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 61.2 bits (147), Expect = 1e-08
Identities = 95/488 (19%), Positives = 194/488 (39%), Gaps = 87/488 (17%)
Query: 480 LTKKNENYKALVRRNYGKRRGRNQQIARPSQEE---------------KVEEKEEDKAEK 524
L+K+ + +L + RRGR + R +QE +E+ + EK
Sbjct: 846 LSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEK 905
Query: 525 TEKKEEEKKDEEEK---DEKEDSKENTKE--KDKIDGTAEETEEREQATPRGRKTANSQG 579
+E +E+ + EE+ E++ S++ + K ++ E + + +P K ++G
Sbjct: 906 SEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEG 965
Query: 580 RRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKG 639
+ S + A + ++ EE P PI T+P T + + + ++
Sbjct: 966 SERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKP--TLKRKKPFLHRRRRV 1023
Query: 640 LVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRR--------HNLDNLLQQHKQKTSRKPR 691
N + + + + +E + F + R +D ++ + + PR
Sbjct: 1024 RKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEE-EEEEDENELFPR 1082
Query: 692 E------ERDVSQCESVASTVSAQEDEDIEASNEEENP----------EDSEVEAVKPSE 735
E +DV +C+S + S E+ED E+ + ++ P D + ++P
Sbjct: 1083 EYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDT 1142
Query: 736 DSP---ENATSRGNTEPAV----------------ELEPTTETAPSTSPSLAVPST--KP 774
+P + +G + + E+ P + A P +++P KP
Sbjct: 1143 STPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKP 1202
Query: 775 ---AEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDP-----PPATKADSVDVEV 826
+E+VE + + + E E+ ++ + AEEG D P A+ ADS +
Sbjct: 1203 KIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSN--- 1259
Query: 827 RVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSAD 886
PE + E + +E+ R SE+ +E +Q + PEP+ + D++A + +
Sbjct: 1260 -SPETETKEPEVEEEEEK--PRVSEEQRQSEE-----EQQELEEPEPEEEEDAAAETAQN 1311
Query: 887 EDVDGEPE 894
+D D + E
Sbjct: 1312 DDHDADDE 1319
Score = 54.3 bits (129), Expect = 1e-06
Identities = 100/461 (21%), Positives = 174/461 (37%), Gaps = 81/461 (17%)
Query: 509 SQEEKVEEKEE----DKAEKTEKKEEEKKDEEEKDEKEDSKENTKEK------DKIDGTA 558
++E +VEE+EE + ++ ++E+++ +E E +E+ED+ T + D+ DG
Sbjct: 1265 TKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHL 1324
Query: 559 EETEERE-QATPRGRKTANSQGRRKGRITRSM--TNEAAAASAAAAAATEEPPPPLPPPP 615
E T+++E + P G ++ + +M + E +EE P
Sbjct: 1325 ESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQ---PSHD 1381
Query: 616 EPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNL 675
+ +E + S EE K+ L+E K E + + + + +
Sbjct: 1382 TSVVSEQMAGSEDDHEEDSHTKEELIE-------------LKEEEEIPHSELDLETVQAV 1428
Query: 676 DNLLQQHKQKTSRKPRE-ERDVSQCESVASTVSAQED------EDIEASNEEENPEDSEV 728
+L Q+ + ++ E ++ C+++ S A ED ED AS E N S V
Sbjct: 1429 QSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHAS--EHNSPISSV 1486
Query: 729 EAVKPSED----SPENATSRGNTEPAVELEPTTETAPS-----TSPSLAVPSTKPAEDES 779
++ PS+ S N + + + E + +APS TSP + VPS +
Sbjct: 1487 QS-HPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQV 1545
Query: 780 VETQVNDSISAE-TAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEG 838
V++ +D S E T E + S GS+C + + S G
Sbjct: 1546 VDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSY---------------G 1590
Query: 839 DNTKERDLDRASEKVEPRDEDLVVAQQINAQRPE----PQSDNDSSATCSADED----VD 890
+ L ++S VV QQ+ + QS +A CS V+
Sbjct: 1591 GLSSSSSLTQSS---------CVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVE 1641
Query: 891 GEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQ 931
P Q+ P P P +P P P PQ Q
Sbjct: 1642 RPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQ 1682
Score = 47.4 bits (111), Expect = 2e-04
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 11/184 (5%)
Query: 683 KQKTSRKP--REERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPEN 740
K++ RKP + R++ + A + + I + + ++SE E V+P ED P
Sbjct: 1164 KKRPGRKPGFKLSREIMPVSTQACVI--EPIVSIPKAGRKPKIQESE-ETVEPKEDMPLP 1220
Query: 741 ATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAE-DESVETQVNDSISAETAEQMDV- 798
+ E E E E + S VP+ PA+ S ET+ + E E+ V
Sbjct: 1221 EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVS 1280
Query: 799 DQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGD----NTKERDLDRASEKVE 854
++Q S EE + P + + E ++H + E D +TK+++L+ + +
Sbjct: 1281 EEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED 1340
Query: 855 PRDE 858
++E
Sbjct: 1341 VKEE 1344
Score = 36.6 bits (83), Expect = 0.31
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 6/80 (7%)
Query: 511 EEKVEEKEEDKAEKTEKKEEE------KKDEEEKDEKEDSKENTKEKDKIDGTAEETEER 564
EE+ EE EE + E+ + +E E K E E++ +++K ++ T
Sbjct: 788 EEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLS 847
Query: 565 EQATPRGRKTANSQGRRKGR 584
+Q P ANSQ R+GR
Sbjct: 848 KQVLPHDSLPANSQPSRRGR 867
Score = 31.6 bits (70), Expect = 10.0
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
Query: 1936 IITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDAIEVISPASS----PAPPQEKLQT 1991
++T+Q+AS + QSS ++ S ++P + P++ P PP ++ Q
Sbjct: 1604 VVTQQMASMGSSCSMMQQSSVQPAANCS--IKSPQSCVVERPPSNQQQQPPPPPPQQPQP 1661
Query: 1992 YQPEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQ-QQLPPSSQ 2035
P+ A Q P +Q +PQQ P P QQ PP SQ
Sbjct: 1662 PPPQPQPAPQPP--PPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQ 1704
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 61.2 bits (147), Expect = 1e-08
Identities = 95/488 (19%), Positives = 194/488 (39%), Gaps = 87/488 (17%)
Query: 480 LTKKNENYKALVRRNYGKRRGRNQQIARPSQEE---------------KVEEKEEDKAEK 524
L+K+ + +L + RRGR + R +QE +E+ + EK
Sbjct: 846 LSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEK 905
Query: 525 TEKKEEEKKDEEEK---DEKEDSKENTKE--KDKIDGTAEETEEREQATPRGRKTANSQG 579
+E +E+ + EE+ E++ S++ + K ++ E + + +P K ++G
Sbjct: 906 SEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEG 965
Query: 580 RRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKG 639
+ S + A + ++ EE P PI T+P T + + + ++
Sbjct: 966 SERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKP--TLKRKKPFLHRRRRV 1023
Query: 640 LVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRR--------HNLDNLLQQHKQKTSRKPR 691
N + + + + +E + F + R +D ++ + + PR
Sbjct: 1024 RKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEE-EEEEDENELFPR 1082
Query: 692 E------ERDVSQCESVASTVSAQEDEDIEASNEEENP----------EDSEVEAVKPSE 735
E +DV +C+S + S E+ED E+ + ++ P D + ++P
Sbjct: 1083 EYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDT 1142
Query: 736 DSP---ENATSRGNTEPAV----------------ELEPTTETAPSTSPSLAVPST--KP 774
+P + +G + + E+ P + A P +++P KP
Sbjct: 1143 STPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKP 1202
Query: 775 ---AEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDP-----PPATKADSVDVEV 826
+E+VE + + + E E+ ++ + AEEG D P A+ ADS +
Sbjct: 1203 KIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSN--- 1259
Query: 827 RVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSAD 886
PE + E + +E+ R SE+ +E +Q + PEP+ + D++A + +
Sbjct: 1260 -SPETETKEPEVEEEEEK--PRVSEEQRQSEE-----EQQELEEPEPEEEEDAAAETAQN 1311
Query: 887 EDVDGEPE 894
+D D + E
Sbjct: 1312 DDHDADDE 1319
Score = 54.3 bits (129), Expect = 1e-06
Identities = 100/461 (21%), Positives = 174/461 (37%), Gaps = 81/461 (17%)
Query: 509 SQEEKVEEKEE----DKAEKTEKKEEEKKDEEEKDEKEDSKENTKEK------DKIDGTA 558
++E +VEE+EE + ++ ++E+++ +E E +E+ED+ T + D+ DG
Sbjct: 1265 TKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHL 1324
Query: 559 EETEERE-QATPRGRKTANSQGRRKGRITRSM--TNEAAAASAAAAAATEEPPPPLPPPP 615
E T+++E + P G ++ + +M + E +EE P
Sbjct: 1325 ESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQ---PSHD 1381
Query: 616 EPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNL 675
+ +E + S EE K+ L+E K E + + + + +
Sbjct: 1382 TSVVSEQMAGSEDDHEEDSHTKEELIE-------------LKEEEEIPHSELDLETVQAV 1428
Query: 676 DNLLQQHKQKTSRKPRE-ERDVSQCESVASTVSAQED------EDIEASNEEENPEDSEV 728
+L Q+ + ++ E ++ C+++ S A ED ED AS E N S V
Sbjct: 1429 QSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHAS--EHNSPISSV 1486
Query: 729 EAVKPSED----SPENATSRGNTEPAVELEPTTETAPS-----TSPSLAVPSTKPAEDES 779
++ PS+ S N + + + E + +APS TSP + VPS +
Sbjct: 1487 QS-HPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQV 1545
Query: 780 VETQVNDSISAE-TAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEG 838
V++ +D S E T E + S GS+C + + S G
Sbjct: 1546 VDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSY---------------G 1590
Query: 839 DNTKERDLDRASEKVEPRDEDLVVAQQINAQRPE----PQSDNDSSATCSADED----VD 890
+ L ++S VV QQ+ + QS +A CS V+
Sbjct: 1591 GLSSSSSLTQSS---------CVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVE 1641
Query: 891 GEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQ 931
P Q+ P P P +P P P PQ Q
Sbjct: 1642 RPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQ 1682
Score = 47.4 bits (111), Expect = 2e-04
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 11/184 (5%)
Query: 683 KQKTSRKP--REERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPEN 740
K++ RKP + R++ + A + + I + + ++SE E V+P ED P
Sbjct: 1164 KKRPGRKPGFKLSREIMPVSTQACVI--EPIVSIPKAGRKPKIQESE-ETVEPKEDMPLP 1220
Query: 741 ATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAE-DESVETQVNDSISAETAEQMDV- 798
+ E E E E + S VP+ PA+ S ET+ + E E+ V
Sbjct: 1221 EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVS 1280
Query: 799 DQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGD----NTKERDLDRASEKVE 854
++Q S EE + P + + E ++H + E D +TK+++L+ + +
Sbjct: 1281 EEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED 1340
Query: 855 PRDE 858
++E
Sbjct: 1341 VKEE 1344
Score = 36.6 bits (83), Expect = 0.31
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 6/80 (7%)
Query: 511 EEKVEEKEEDKAEKTEKKEEE------KKDEEEKDEKEDSKENTKEKDKIDGTAEETEER 564
EE+ EE EE + E+ + +E E K E E++ +++K ++ T
Sbjct: 788 EEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLS 847
Query: 565 EQATPRGRKTANSQGRRKGR 584
+Q P ANSQ R+GR
Sbjct: 848 KQVLPHDSLPANSQPSRRGR 867
Score = 31.6 bits (70), Expect = 10.0
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
Query: 1936 IITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDAIEVISPASS----PAPPQEKLQT 1991
++T+Q+AS + QSS ++ S ++P + P++ P PP ++ Q
Sbjct: 1604 VVTQQMASMGSSCSMMQQSSVQPAANCS--IKSPQSCVVERPPSNQQQQPPPPPPQQPQP 1661
Query: 1992 YQPEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQ-QQLPPSSQ 2035
P+ A Q P +Q +PQQ P P QQ PP SQ
Sbjct: 1662 PPPQPQPAPQPP--PPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQ 1704
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 61.2 bits (147), Expect = 1e-08
Identities = 161/869 (18%), Positives = 314/869 (36%), Gaps = 137/869 (15%)
Query: 16 EQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQQQQQLRRR---PSLL 72
E+ R + T P +H + + SS SQ+ +Q+ R+R PS
Sbjct: 305 ERQREKRDKPRSTSPAGQHHSPISSRHHSSS----SQSGSSIQRHSPSPRRKRTPSPSYQ 360
Query: 73 SEFHPGSDRPQERRTSYEPFHPGPSPVDHDS--------LESKRPRLEQVSDSHFQRVSA 124
P P R S P H SP S E R E+ S SH +R
Sbjct: 361 RTLTP----PLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRR--- 413
Query: 125 AVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEELIQS 184
H E R D +KD ++E DQ++S E
Sbjct: 414 ------HERREDTRGKRDREKDSREEREYE------------QDQSSSRDHRDDREPRDG 455
Query: 185 MDRVDREIAKVEQQILKLK--KKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIYDE 242
DR D + +++ + + +++ + + E P H + D
Sbjct: 456 RDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDT 515
Query: 243 NRKK---AEEAHKIFEGLGPKVELPLYNQPSDTKVYHEN-------IKTNQVMRKKLILF 292
+RK+ EE+ L + S T++ +E+ I+ +++ R + +
Sbjct: 516 HRKEDTYPEESRSYGRN-------HLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVP 568
Query: 293 FKRRNHARKQREQKICQRYDQ--LMEAWEKKVDRIENN--PRRKAKESKTREYYEKQFPE 348
+R R +I ++WE + E + P R ++ +E++ E
Sbjct: 569 ELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGE 628
Query: 349 IRKQREQQERFQRVGQ--RGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPM 406
R +R+ +ER QR R G + + R E +D + ++ + + R
Sbjct: 629 -RDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARER-------- 679
Query: 407 MFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYL 466
D E+ R + E + K+R+ E+E +++ + K
Sbjct: 680 --DRERERDRERERERERERDREREKEREL-------ERERAREREREREK--------- 721
Query: 467 ERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTE 526
ER D + ++ E + + +R R ++ R + E+ E+E ++A + +
Sbjct: 722 ERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERD 781
Query: 527 KKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRIT 586
K+ E ++D E+KD+ D + +E+ + D + + ++ R R + R+ +
Sbjct: 782 KERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR 841
Query: 587 RSMTNEAAAASAAAAAATEEP-PPPLPPPPEPISTEPVETS-----RWTEEEMEVAKKGL 640
R + ++ A ++ + + P E S P + RW EE+ + +K
Sbjct: 842 REHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERK-- 899
Query: 641 VEHGRNW--AAIAKMVGT--KSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREE-RD 695
E R + + + V + K Q + + R ++ Q ++TS + +E +
Sbjct: 900 -ESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKK 958
Query: 696 VSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEP 755
++ + ++D IE N E ED +V P + + + + + + +
Sbjct: 959 KAKIQKKPIKKKKEDDVGIERGNIETTSEDGQV--FSPKKGQKKKSIEKKRKKSKGDSDI 1016
Query: 756 TTETAPSTSPSLAVPSTKP--AEDESVE-----------------TQVNDSISAETAEQM 796
+ E A S P T P ++E VE T +D + ++
Sbjct: 1017 SDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRT 1076
Query: 797 DVDQQEHSAEE----------GSVCDPPP 815
+V + EH+A S+ PPP
Sbjct: 1077 EVTEAEHTATATTPGSTPSPLSSLLPPPP 1105
Score = 45.8 bits (107), Expect = 5e-04
Identities = 141/824 (17%), Positives = 300/824 (36%), Gaps = 117/824 (14%)
Query: 138 RASADAKKDPAFGGKH------------EAPSSPISGQPCGD----DQNASPSKLSK--- 178
R + D +D +F +H + PSSPI Q D D+ ++ +
Sbjct: 611 RDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDD 670
Query: 179 --EELIQSMDRV---DREIAKV-EQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKH 232
+E + DR DRE + E++ + ++K+++LE E A+ E E+ +
Sbjct: 671 RRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRD 730
Query: 233 RSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILF 292
R D +R++ E + D + E + + ++
Sbjct: 731 R-------DHDRERERERER------------------DREKEREREREERERERER--- 762
Query: 293 FKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQ 352
+R ++RE++ + D+ E D+ + R+ K + RE ++ + +
Sbjct: 763 -ERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRE--DRNPRDGHDE 819
Query: 353 REQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQL-------SVIPP 405
R+ ++R++ G S R S+ + ++ + + Q+ S+ P
Sbjct: 820 RKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPS 879
Query: 406 MMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASY 465
+ + Q R K + ++ + Y++++ + +K+ + + ++ +
Sbjct: 880 HLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRA--QDI 937
Query: 466 LERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEE------KEE 519
+ D +N+ + ++ K++ + I R + E E+ K+
Sbjct: 938 IGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKG 997
Query: 520 DKAEKTEKKEEEKKDEEEKDEKEDSKENTKE----------KDKI-------DGTAEETE 562
K + EKK ++ K + + ++E ++++ K+ K+++ +G E+++
Sbjct: 998 QKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQ 1057
Query: 563 EREQATPRGRKTANSQGRRKGRITRSMTNEAA-AASAAAAAATEEPPPPLPPPPEPISTE 621
++E TA S + R+ EA A+A +T P L PPP P++T
Sbjct: 1058 KKED-------TAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATA 1110
Query: 622 PVETSRWT-EEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQ 680
T T A + A T + R ++ +
Sbjct: 1111 TATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVET 1170
Query: 681 QHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPEN 740
H + R+ D + S+ S S + S +P + + +
Sbjct: 1171 PHVTIEDAQHRKPMDQKRSSSLGSNRSNRS----HTSGRLRSPSNDSAHRSGDDQSGRKR 1226
Query: 741 ATSRG--NTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDV 798
G + E LE T E + +P+ S + Q + S S+ + +
Sbjct: 1227 VLHSGSRDREKTKSLEITGERKSRID---QLKRGEPSRSTSSDRQDSRSHSSRRSSP-ES 1282
Query: 799 DQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDE 858
D+Q HS GS D + R + + E +T++R+ DR ++K PR+
Sbjct: 1283 DRQVHS-RSGSF------DSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNR 1335
Query: 859 DLVVAQQINAQRPEPQS---DNDSSATCSADEDVDGEPERQRMF 899
D ++ +R + D + S + D + +R R F
Sbjct: 1336 DRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTF 1379
Score = 41.6 bits (96), Expect = 0.010
Identities = 72/417 (17%), Positives = 136/417 (32%), Gaps = 28/417 (6%)
Query: 492 RRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEK 551
+ N K++G P E + ++ K + K E+K + KD D + +++
Sbjct: 252 KTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKR 311
Query: 552 DKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPL 611
DK T+ + + R +++ G R + S + + + T
Sbjct: 312 DKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSA 371
Query: 612 PPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKR 671
P P + P + +KG +H R + + + + + K R
Sbjct: 372 SPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSR 431
Query: 672 --RHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVE 729
R + + R+PR+ RD ++ D+ S E + E
Sbjct: 432 EEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKE 491
Query: 730 AVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSIS 789
+ P + + +T P S S +ES T++ +
Sbjct: 492 SRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSY---GRNHLREESSRTEIRNESR 548
Query: 790 AETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRA 849
E+ ++ D+ S G V + P S ++ ++H+S N+ D
Sbjct: 549 NESRSEIRNDRMGRS--RGRVPELPEKGSRGSRGSQI---DSHSS-----NSNYHDSWET 598
Query: 850 SEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPERQRMFPMDSKPS 906
RD P+ DN A S+ E GE +R+ D +PS
Sbjct: 599 RSSYPERDR-------------YPERDNRDQARDSSFERRHGERDRRDNRERDQRPS 642
Score = 40.0 bits (92), Expect = 0.028
Identities = 77/412 (18%), Positives = 141/412 (34%), Gaps = 85/412 (20%)
Query: 507 RPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEK-DEKEDSKENTKEKDKIDGTAEETEERE 565
R EK E ++ +++ E ++D K D ++DS+E + + + + ++RE
Sbjct: 392 RSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDRE 451
Query: 566 QATPRGRKTA-NSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVE 624
R R+ A +++ RR+ R +R M + S E +
Sbjct: 452 PRDGRDRRDARDTRDRRELRDSRDMRD---------------------------SREMRD 484
Query: 625 TSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQ 684
SR T+E + +++ +Y+ R D +
Sbjct: 485 YSRDTKESRD----------------------PRDSRSTRDAHDYRDREGRDT-----HR 517
Query: 685 KTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSE------DSP 738
K P E R S +E E NE N SE+ + + P
Sbjct: 518 KEDTYPEESR------SYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELP 571
Query: 739 ENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDV 798
E SRG+ ++ + + S S+ P D E D + E+
Sbjct: 572 EKG-SRGSRGSQIDSHSSNS---NYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHG 627
Query: 799 DQQEHSAEEGSVCDPPPAT---KADSVDVEVRVPENHASKV---------EGDNTKERDL 846
++ E P + D ++ + R E +V E D +ERD
Sbjct: 628 ERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDR 687
Query: 847 DRASEKVEPRDEDLVVAQQINAQRP-EPQSDNDSSATCSADEDVDGEPERQR 897
+R E+ RD + +++ +R E + + + D D D + ER+R
Sbjct: 688 ERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERER 739
Score = 35.8 bits (81), Expect = 0.53
Identities = 17/23 (73%), Positives = 18/23 (78%)
Query: 1713 EREREREREKERERERIAAASSD 1735
ERERERERE+ERERER A D
Sbjct: 759 ERERERERERERERERERARERD 781
Score = 34.3 bits (77), Expect = 1.5
Identities = 33/169 (19%), Positives = 71/169 (42%), Gaps = 33/169 (19%)
Query: 482 KKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKD------- 534
+ E + VR+ + R R ++ + ++E E +EE+ +T + + + D
Sbjct: 103 RNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVH 162
Query: 535 ------EEEKDEKEDSK---ENTKEKDKI----DGTAEETEEREQATPRGRKTANSQGRR 581
+ +K ++E K EN +++++I + + E + +P RK++ S R+
Sbjct: 163 ELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRK 222
Query: 582 KGRITRSMTNEAAAASAAAAAATEE-------------PPPPLPPPPEP 617
+ S + + SA ++ ++ P P PPPP P
Sbjct: 223 SSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIP 271
Score = 34.3 bits (77), Expect = 1.5
Identities = 15/16 (93%), Positives = 16/16 (100%)
Query: 1713 EREREREREKERERER 1728
ERERER+REKERERER
Sbjct: 738 ERERERDREKERERER 753
Score = 34.3 bits (77), Expect = 1.5
Identities = 15/16 (93%), Positives = 16/16 (100%)
Query: 1713 EREREREREKERERER 1728
ERERERERE+ERERER
Sbjct: 755 ERERERERERERERER 770
Score = 34.3 bits (77), Expect = 1.5
Identities = 15/16 (93%), Positives = 16/16 (100%)
Query: 1713 EREREREREKERERER 1728
ERERERERE+ERERER
Sbjct: 757 ERERERERERERERER 772
Score = 33.1 bits (74), Expect = 3.4
Identities = 14/16 (87%), Positives = 16/16 (100%)
Query: 1713 EREREREREKERERER 1728
ERER+RERE+ERERER
Sbjct: 682 ERERDRERERERERER 697
Score = 32.7 bits (73), Expect = 4.5
Identities = 14/20 (70%), Positives = 17/20 (85%)
Query: 1709 AASAEREREREREKERERER 1728
A +RERER+RE+ERERER
Sbjct: 676 ARERDRERERDRERERERER 695
Score = 32.3 bits (72), Expect = 5.9
Identities = 14/15 (93%), Positives = 15/15 (100%)
Query: 1714 REREREREKERERER 1728
REREREREKER+RER
Sbjct: 713 REREREREKERDRER 727
Score = 32.0 bits (71), Expect = 7.6
Identities = 13/16 (81%), Positives = 16/16 (100%)
Query: 1713 EREREREREKERERER 1728
ER+RERERE+ERER+R
Sbjct: 684 ERDRERERERERERDR 699
Score = 32.0 bits (71), Expect = 7.6
Identities = 13/16 (81%), Positives = 16/16 (100%)
Query: 1713 EREREREREKERERER 1728
+RERERERE+ER+RER
Sbjct: 686 DRERERERERERDRER 701
Score = 32.0 bits (71), Expect = 7.6
Identities = 13/16 (81%), Positives = 16/16 (100%)
Query: 1713 EREREREREKERERER 1728
ERERERERE++RERE+
Sbjct: 688 ERERERERERDREREK 703
Score = 32.0 bits (71), Expect = 7.6
Identities = 13/16 (81%), Positives = 16/16 (100%)
Query: 1713 EREREREREKERERER 1728
ERERERER++ERE+ER
Sbjct: 690 ERERERERDREREKER 705
Score = 32.0 bits (71), Expect = 7.6
Identities = 13/16 (81%), Positives = 16/16 (100%)
Query: 1713 EREREREREKERERER 1728
ERERERER++E+ERER
Sbjct: 736 ERERERERDREKERER 751
Score = 31.6 bits (70), Expect = 10.0
Identities = 14/16 (87%), Positives = 15/16 (93%)
Query: 1713 EREREREREKERERER 1728
ERER+REREKERE ER
Sbjct: 694 ERERDREREKERELER 709
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 60.1 bits (144), Expect = 3e-08
Identities = 308/1596 (19%), Positives = 511/1596 (32%), Gaps = 284/1596 (17%)
Query: 734 SEDSPENATSRGN-TEPAVELEPTT-ETAPSTSPSLAVPSTKPAEDESVETQVNDSISAE 791
S S E T G+ T P++ + TT T+P + + P+T + S E+ + S
Sbjct: 1418 SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGS 1477
Query: 792 TAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRV-PENHASKVEGDNTKERDLDRAS 850
T D S + P + + E + P + + G +
Sbjct: 1478 THTTAFPD----STTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 1533
Query: 851 EKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCS-ADEDVDGEPERQRMFPMDSKPSLLN 909
+ +D + + + A P S T + A G E F S PS
Sbjct: 1534 TETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTF--QSWPS--- 1588
Query: 910 PTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHE 969
SS P+P P VS T + P TP + ++ + E
Sbjct: 1589 -------SSDTTPSPPG-------TTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 1634
Query: 970 SALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWE---VLQPAPHQVITNLPEGVRLPT 1026
S + SS GT+ P R V +P + + E LP
Sbjct: 1635 STTVH--------------SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPG 1680
Query: 1027 TRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQETPKPSVGSI 1086
+ T + ++ S + + S G TSH++ T T P
Sbjct: 1681 STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG---- 1736
Query: 1087 SLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAIQEGSITR 1146
S T+P + QE + S + L TA ++ S T
Sbjct: 1737 ------------STTMPGVSQESTASHSSPGSTDTTLSPGST------TASSLGPESTTF 1778
Query: 1147 GTPTSKISVESIP---SLRGSITQGTPALPQTGIPTEALVKGSISRMPIEDSSPEKGREE 1203
+ +P + G + TP TG P L
Sbjct: 1779 HSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTL--------------------- 1817
Query: 1204 AASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLKRSYESVEGNIKQGMSMRES 1263
+ G +G+S S+ + K+ + +A S+ S S +
Sbjct: 1818 -SPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASST 1876
Query: 1264 PVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYPKQIKRESP 1323
+ E + P + + R+ SG + + T ++ + +P
Sbjct: 1877 TLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFP-------- 1928
Query: 1324 PIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPIIEGSIS 1383
E + G+ + T+ +I P +T ++E
Sbjct: 1929 -----ESSTASGRSEESRTSHSSTTHTISSPP----------------STTSALVE---- 1963
Query: 1384 QGTPIKFDNNSGQSAIKHNVKSLIT-GPSKLSRGMPPLEIVPENIKVVERGKYEDVKAGE 1442
P + ++ G +A H S T G S+ S + I + R V GE
Sbjct: 1964 --EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARST-TSVLLGE 2020
Query: 1443 TVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYD-DTSARRTPVSYQNTMSRGSPMMNR 1501
+ TS +SSG S+ + L P + +PG+ + T+ +P S T+S S
Sbjct: 2021 ST----TSPISSG-SMETTAL---PGSTTTPGLSEKSTTFHSSPRSPATTLSPAS----- 2067
Query: 1502 TSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVYR 1561
T+ +S +T+H R + T + P + PG+ HS GST +
Sbjct: 2068 TTSSGVSEESTTSHSRPGS---THTTAFPDSTTTPGLS---RHSTTSHSSPGSTDTTLLP 2121
Query: 1562 SHLPT----------HLDPAMPFHRALDPAAAAYLFQRQLSPT----PGYPSQYQLYAME 1607
+ T H P AL P + L Q S T PG
Sbjct: 2122 ASTTTSGPSQESTTSHSSPGST-DTALSPGSTTALSFGQESTTFHSSPG----------- 2169
Query: 1608 NTRQTILNDYITSQQM-QVNLRPDVARGLSPRE--QPLGLPYPATRGIIDLTNMPP--TI 1662
+T T+ D TS + + + R + G SPR P P +G P T
Sbjct: 2170 STHTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTLSPASSTSPGLQGESTAFQTHPASTH 2228
Query: 1663 LVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPT-----HLAAAAS----AE 1713
P P T+T P++ T + + P + ++S + GH H + AS +
Sbjct: 2229 TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 2288
Query: 1714 REREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPS 1773
E RI+ S+++ PGS + +P + T P
Sbjct: 2289 AHSTTSGRGESTTSRISPGSTEITTLPGS-------------TTTPGLSEASTTFYSSP- 2334
Query: 1774 VFQGTNGTSVITPLDPTAQLRIMPLPAGGPS-ISQGLPASRYNTAADALAALVDAAASAP 1832
+ T+ ++P T+ L G S S+ P S ++T + A+ + P
Sbjct: 2335 ----RSPTTTLSPASMTS------LGVGEESTTSRSQPGSTHSTVS-------PASTTTP 2377
Query: 1833 QMDVSKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQ-CLYTSSAFPSGK 1891
+ T E + R+ S + + E T S L+T + SG
Sbjct: 2378 GLSEESTTVYSSSPGSTETTVFPRTPTTSVRGE-EPTTFHSRPASTHTTLFTEDSTTSGL 2436
Query: 1892 PQPHSSVVYSEAGKDKGPP----------PKSRYEEELRTRGKTTITAANFIDVIITRQI 1941
+ ++ S A G P + + + G T A + ++
Sbjct: 2437 TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGEST 2496
Query: 1942 ------ASDKDARERGSQSSDSSSSLSSHRYETPSDAIEVISPASSPAP-PQEKLQTYQP 1994
+S + GS ++ S S S+ Y +P +SPA++ + E+ T
Sbjct: 2497 PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHS 2556
Query: 1995 EVVKANQAENDPTRQYEGPLHHYRPQQESPSPQQQ--LPPSSQAEGMGQVPRTHRLITLA 2052
+ + + G H SP LP S+ G Q T
Sbjct: 2557 QPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTT------- 2609
Query: 2053 DHICQIITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHH 2112
H T ++ ++TF +SP + +T T++ E+ + VH
Sbjct: 2610 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTR-VH- 2667
Query: 2113 QRPGSRVSPENLVDKSRGSRPGKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRG 2172
S SP + + + PG E + + P + P P S
Sbjct: 2668 ---SSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPP------------STAT 2712
Query: 2173 AEPAEQRNDARSPGSISYLPSFFTKLENTSPMVKSKKQEIFRK-------------LNSS 2219
A E RSPGS + F TS S+K IF +S
Sbjct: 2713 APVEESTTYHRSPGSTP--TTHFPASSTTSG--HSEKSTIFHSSPDASGTTPSSAHSTTS 2768
Query: 2220 GGGDSDMAAAQPG-TEIFNLPAVTTSGSVSSRGHSF 2254
G G+S + PG TEI LP TT+ +S +F
Sbjct: 2769 GRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 2804
Score = 55.1 bits (131), Expect = 8e-07
Identities = 307/1586 (19%), Positives = 502/1586 (31%), Gaps = 291/1586 (18%)
Query: 734 SEDSPENATSRGN-TEPAVELEPTT-ETAPSTSPSLAVPSTKPAEDESVETQVNDSISAE 791
S S E T G+ T P++ + TT T+P + + P+T + S E+ + S
Sbjct: 2975 SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGS 3034
Query: 792 TAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRV-PENHASKVEGDNTKERDLDRAS 850
T D S + P A+ + E + P + + G +
Sbjct: 3035 THTTAFPD----STTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 3090
Query: 851 EKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCS-ADEDVDGEPERQRMFPMDSKPSLLN 909
+ +D + + + A P S T + A G E F S PS
Sbjct: 3091 TETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTF--QSWPS--- 3145
Query: 910 PTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHE 969
SS P+P P VS T + P TP + ++ + E
Sbjct: 3146 -------SSDTTPSPPG-------TTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 3191
Query: 970 SALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWE---VLQPAPHQVITNLPEGVRLPT 1026
S + SS GT+ P R V +P + + E LP
Sbjct: 3192 STTVH--------------SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPG 3237
Query: 1027 TRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQETPKPSVGSI 1086
+ T + ++ S + + S G TSH++ T T P
Sbjct: 3238 STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG---- 3293
Query: 1087 SLGLPR-QQESAKSATLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAIQEGSIT 1145
S +P QES S + P SP S + G H G G+ + +
Sbjct: 3294 STTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSG-----PGSTETTLLP 3348
Query: 1146 RGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVKGSISRMPIEDSSPEKGREEAA 1205
T S G + TP TG P L +
Sbjct: 3349 DNTTAS-----------GLLEASTPVHSSTGSPHTTL----------------------S 3375
Query: 1206 SKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLKRSYESVEGNIKQGMSMRESPV 1265
G +G+S S+ N K+ + +A S+ S S + +
Sbjct: 3376 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 3435
Query: 1266 SAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYPKQIKRESPPI 1325
E + P + + R+ SG + + T ++ + +P
Sbjct: 3436 GRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFP---------- 3485
Query: 1326 RAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPIIEGSISQG 1385
E T G+ + T+ +I P +T ++E
Sbjct: 3486 ---ESDTTSGRGEESTTSHSSTTHTISSAP----------------STTSALVE------ 3520
Query: 1386 TPIKFDNNSGQSAIKHNVKSLIT-GPSKLSRGMPPLEIVPENIKVVERGKYEDVKAGETV 1444
P + ++ G +A H S T G S+ S + I + R V GE+
Sbjct: 3521 EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARST-TSVLLGEST 3579
Query: 1445 RSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYD-DTSARRTPVSYQNTMSRGSPMMNRTS 1503
TS +SSG S+ + L P + +PG+ + T+ +P S T+S S T+
Sbjct: 3580 ----TSPISSG-SMETTAL---PGSTTTPGLSEKSTTFHSSPRSPATTLSPAS-----TT 3626
Query: 1504 DVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHR------GSTAG 1557
+S +T+H R + T + P + PG+ + S P ST
Sbjct: 3627 SSGVSEESTTSHSRPGS---THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 3683
Query: 1558 EVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT----PGYPSQYQLYAMENTRQTI 1613
T + AL P + L Q S T PG +T T+
Sbjct: 3684 SGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPG-----------STHTTL 3732
Query: 1614 LNDYITSQQM-QVNLRPDVARGLSPRE--QPLGLPYPATRGIIDLTNMPP--TILVPHPG 1668
D TS + + + R + G SPR P P +G P T P P
Sbjct: 3733 FPDSTTSSGIVEASTRVHSSTG-SPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPP 3791
Query: 1669 GTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPT-----HLAAAAS----AERERERE 1719
T+T P++ T + + P + ++S + GH H + AS +
Sbjct: 3792 STATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTS 3851
Query: 1720 REKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTN 1779
E RI+ S+++ PGS + +P + T P +
Sbjct: 3852 GRGESTTSRISPGSTEITTLPGS-------------TTTPGLSEASTTFYSSP-----RS 3893
Query: 1780 GTSVITPLDPTAQLRIMPLPAGGPS-ISQGLPASRYNTAADALAALVDAAASAPQMDVSK 1838
T+ ++P T+ L G S S+ P S ++T + A+ + P +
Sbjct: 3894 PTTTLSPASMTS------LGVGEESTTSRSQPGSTHSTVS-------PASTTTPGLSEES 3940
Query: 1839 TKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQ-CLYTSSAFPSGKPQPHSS 1897
T E + RS S +++ E T S L+T + SG + ++
Sbjct: 3941 TTVYSSSPGSTETTVFPRSTTTSVRRE-EPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 3999
Query: 1898 VVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDS 1957
S A G P T+T A+ + T +S + S +
Sbjct: 4000 FPGSPASTQTGLP--------------ATLTTADLGEESTTFPSSSGSTGTKLSPARSTT 4045
Query: 1958 SSSLSSHRYETPS----DAIEVISPASSPAPP--QEKLQTYQPEVVKANQAENDPTRQYE 2011
S + TPS + E + SP P EK T+ + + T
Sbjct: 4046 SGLVGE---STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 4102
Query: 2012 GPLHHYRPQQESPSPQQ--QLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVS 2069
G P P S+ G+ Q P T H Q T+ +
Sbjct: 4103 GVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTT-------SHSSQGSTEATLSPGST 4155
Query: 2070 SQTPQQPPTSTFQNSP--------------SALV--STPVRTKTSNRYSPESQAQSVHHQ 2113
+ + ++TF +SP S LV STP + T + ++ + A S
Sbjct: 4156 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASST--- 4212
Query: 2114 RPGSRVSPENLVDKSRGSRPGKSPERSHVSSEPYEPIS-----PPQVPVVHEKQDSLLLL 2168
+ + E+ +S S +P ++ P E + P P H S L
Sbjct: 4213 --STGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTL- 4269
Query: 2169 SQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAA 2228
E SPG+ + F TS +V G +
Sbjct: 4270 ----GRSEESTTVHSSPGATG--TALFPTRSATSVLV---------------GEPTTSPI 4308
Query: 2229 AQPGTEIFNLPAVTTSGSVSSRGHSF 2254
+ TE LP TT+ +S + +F
Sbjct: 4309 SSGSTETTALPGSTTTAGLSEKSTTF 4334
Score = 53.1 bits (126), Expect = 3e-06
Identities = 300/1486 (20%), Positives = 453/1486 (30%), Gaps = 243/1486 (16%)
Query: 1025 PTTRPTRPPPP--------LIPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQ 1076
P ++ T P PP L +S + +S + S + G T H+ T
Sbjct: 3393 PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 3452
Query: 1077 ETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRG-- 1134
TP P+ + S GL +ES + P Q P S + G H
Sbjct: 3453 TTPSPARSTTS-GLV--EESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTIS 3509
Query: 1135 -----TAGAIQEGSITRGTP-------------TSKISVESIPSLRGSITQGTPALPQTG 1176
T+ ++E + +P TS S ES S GT LP
Sbjct: 3510 SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARS 3569
Query: 1177 IPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPR 1236
T +++ G + PI S E A G G S ++ + + T SP
Sbjct: 3570 --TTSVLLGESTTSPISSGS----METTALPGSTTTPGLSEKSTTFHSSPRSPATTLSP- 3622
Query: 1237 TAHEISLKRSYESVEGNIKQGMSMRES-PVSAPLEGL-----ICRALPRGSPHSDLKERT 1290
A S S ES + + G + + P S GL + P + + L T
Sbjct: 3623 -ASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAST 3681
Query: 1291 VLSGSIMQGTPR-----ATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITT-- 1343
SGS + T +T + G +ES + G+ D T+
Sbjct: 3682 TTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSG 3741
Query: 1344 IKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNV 1403
I E +H T R T ST P ++G +A + +
Sbjct: 3742 IVEASTRVHSS------TGSPRTTLSPASSTSPGLQGE--------------STAFQTHP 3781
Query: 1404 KSLITGPSKLSRGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTL 1463
S T PS S P+E E Y S +SG S +
Sbjct: 3782 ASTHTTPSPPSTATAPVE---------ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 3832
Query: 1464 HEAPKAQ---------LSPGIYDDTSARRTPVSYQNTMSRGS---PMMNRTSDVTISSNK 1511
H +P A + G + T++R +P S + T GS P ++ S SS +
Sbjct: 3833 HSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 3892
Query: 1512 STNHERKSTLTPTQRESI---------------------PAKSPVPGVDP----VVSHSP 1546
S +TL+P S+ PA + PG+ V S SP
Sbjct: 3893 SPT----TTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSP 3948
Query: 1547 FDPHHRGSTAGEVY--------RSHLPT--HLDPAMPFHRALDPAAAAYLFQRQLSPTPG 1596
GST V+ R PT H PA + + + PG
Sbjct: 3949 ------GSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG 4002
Query: 1597 YPSQYQLYAMENTRQTILNDYIT-----SQQMQVNLRP--DVARGLSPREQPLGLPYPAT 1649
P+ Q L + T S L P GL P L +T
Sbjct: 4003 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSST 4062
Query: 1650 RGIIDLTNMPPTILVPHPGGTST-----PPMDRITYIPGTQITFPPRPYNSASMSPGHPT 1704
+ T +P + P ST P T P T + +S S S T
Sbjct: 4063 ----ETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGST 4118
Query: 1705 HLAAAASAEREREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQ 1764
H A + +E + S++ L PGS G SP
Sbjct: 4119 HTTAFPDSTTTSGLSQEPTTSHS--SQGSTEATLSPGSTTASSLGQQSTTFHSSPG--DT 4174
Query: 1765 ETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAAL 1824
ET L ++ G S T T L PA S S GL +T + +
Sbjct: 4175 ETTLLPDDTITSGLVEASTPTH-SSTGSLHTTLTPAS--STSTGLQEE--STTFQSWPSS 4229
Query: 1825 VDAAASAPQMDVSKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTS 1884
D S P + S +R + +A S +++ V ++S
Sbjct: 4230 SDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTV--------HSS 4281
Query: 1885 SAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASD 1944
P S G+ P S E G TT + S
Sbjct: 4282 PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 4341
Query: 1945 KDARERGSQSSDSSSSLSSHRYETPSDAIEVISPASSPAP--PQEKLQTYQ-PEVVKANQ 2001
S +S S S+ + P P+S+ P QE ++ P
Sbjct: 4342 DTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTL 4401
Query: 2002 AENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQ 2061
+ T GP + LP ++ A G+ + T + H
Sbjct: 4402 SPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTL---- 4457
Query: 2062 DFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSP 2121
+ T +Q ++TFQ+ P++ +TP T++ + + + H P S +P
Sbjct: 4458 -----SPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF---VELSTTSHGSPSS--TP 4507
Query: 2122 ENLVDKSRGSRPGKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRND 2181
S + G+S E + V S P + P PA
Sbjct: 4508 TTHFSAS-STTLGRSEESTTVHSSPVATATTP--------------------SPARSTTS 4546
Query: 2182 ARSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLN-SSGGGDSDMAAAQPGTEIFNLPA 2240
S +Y ++SP S + F + N +SG G+ + T +
Sbjct: 4547 GLVEESTTY---------HSSP--GSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAP 4595
Query: 2241 VTTSGSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTS 2300
TTS V + P S G ++ H + V+P + TS
Sbjct: 4596 STTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTS 4655
Query: 2301 VVTSGETRREEGDPSPHS----GGVCKPKLISKSNS-RKSKSPIPGQGYLGTE----RPS 2351
V+ T S + G P L KS + S S P + + R
Sbjct: 4656 VLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSE 4715
Query: 2352 SVSSVHSEGDYHRQTP-------------GWAWEDRPSSTGSTQFP 2384
++VHS TP A+ P ST + FP
Sbjct: 4716 ESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFP 4761
Score = 43.9 bits (102), Expect = 0.002
Identities = 240/1245 (19%), Positives = 410/1245 (32%), Gaps = 205/1245 (16%)
Query: 1025 PTTRPTRPPPPLIPSS----KTTVASEKPSFIMG-----GSISQGTPGTYLTSHNQASYT 1075
P T PPP +S ++T P S + G T H ++T
Sbjct: 480 PVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHT 539
Query: 1076 QETPKPSVGSI-------SLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLVRAQH 1128
+ + + ++ SLG S+T+ +E ++ +S P+ +
Sbjct: 540 KSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEES---KASHSSPDAMATTV-- 594
Query: 1129 EGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQ-----------GTPALPQTGI 1177
+ G+ ++ G T +P S S+E+ +L GS T+ +P P T
Sbjct: 595 --LPAGSTPSVLVGDSTP-SPISSGSMETT-ALPGSTTKPGLSEKSTTFYSSPRSPDTTH 650
Query: 1178 PTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRT 1237
++ +S S A G G S + + + T SP +
Sbjct: 651 LPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGS 710
Query: 1238 AHEISLKRSY---ESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLK------- 1287
SL Y S G+ + + + S LE + SPH+ L
Sbjct: 711 TTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTR 770
Query: 1288 --ERTVL----SGSIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGI 1341
E T S + P TT +F + P + T G +
Sbjct: 771 QGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEEST 830
Query: 1342 TTIKEMG--RSIHEIPRQDILTQESRKTPEVVQSTRPIIEGSISQGT-----PIKFDNNS 1394
T G +++H P D + ++ ST I + S + P + ++
Sbjct: 831 TYHSSPGSTQTMH-FPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP 889
Query: 1395 GQSAIKHNVKSLIT-GPSKLSRGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVS 1453
G +A H S T G S+ S + I + R V GE+ TS +S
Sbjct: 890 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARST-TSVLLGEST----TSPIS 944
Query: 1454 SGPSVLRSTLHEAPKAQLSPGIYD-DTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKS 1512
SG S+ + L P + +PG+ + T+ +P S T+S S T+ +S +
Sbjct: 945 SG-SMETTAL---PGSTTTPGLSERSTTFHSSPRSPATTLSPAS-----TTSSGVSEEST 995
Query: 1513 TNHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAM 1572
T+ R + T + P + PG+ HS GST + LP +
Sbjct: 996 TSRSRPGS---THTTAFPDSTTTPGLS---RHSTTSHSSPGSTDTTL----LPASTTTSG 1045
Query: 1573 PFHRALDPAAAAYLFQRQLSPTP------GYPSQYQLYAMENTRQTILNDYITSQQM-QV 1625
P + +++ LSP G S +T T+ D TS + +
Sbjct: 1046 PSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA 1105
Query: 1626 NLRPDVARGLSPRE--QPLGLPYPATRGIIDLTNMPP--TILVPHPGGTSTPPMDRITYI 1681
+ R + G SPR P P +G P T P P T+T P++ T
Sbjct: 1106 STRVHSSTG-SPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 1164
Query: 1682 PGTQITFPPRPYNSASMSPGHPT-----HLAAAAS----AEREREREREKERERERIAAA 1732
+ + P + ++S + GH H + AS + E RI+
Sbjct: 1165 HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 1224
Query: 1733 SSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQ 1792
S+++ PGS + +P + T P + T+ ++P T+
Sbjct: 1225 STEITTLPGS-------------TTTPGLSEASTTFYSSP-----RSPTTTLSPASMTS- 1265
Query: 1793 LRIMPLPAGGPS-ISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKESKHEAARLEE 1851
L G S S+ P S ++T + A+ + P + T E
Sbjct: 1266 -----LGVGEESTTSRSQPGSTHSTVS-------PASTTTPGLSEESTTVYSSSRGSTET 1313
Query: 1852 NLRSRSAAVSEQQQLEQKTLEVEKRSVQ-CLYTSSAFPSGKPQPHSSVVYSEAGKDKGPP 1910
+ S S + E T S L+T + SG + ++ S A G P
Sbjct: 1314 TVFPHSTTTSVHGE-EPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLP 1372
Query: 1911 ----------PKSRYEEELRTRGKTTITAANFIDVIITRQI------ASDKDARERGSQS 1954
+ + + G A + ++ +S + GS +
Sbjct: 1373 ATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT 1432
Query: 1955 SDSSSSLSSHRYETPSDAIEVISPA------------SSPAPPQEKLQTYQPEVVKANQA 2002
+ S S S+ Y +P +SPA +S + P T P+ +
Sbjct: 1433 TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDL 1492
Query: 2003 ENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQD 2062
+PT + + + P S+ A +GQ T +
Sbjct: 1493 SQEPTTSH---------SSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDT 1543
Query: 2063 FARNQVSSQTPQ---------------------QPPTSTFQNSPSALVSTPVRTKTSNRY 2101
V + TP Q ++TFQ+ PS+ +TP T+
Sbjct: 1544 ITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTT--- 1600
Query: 2102 SPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSSEP 2146
+ + + +H RP S +P S + G+S E + V S P
Sbjct: 1601 AAPVEVSTTYHSRPSS--TPTTHFSAS-STTLGRSEESTTVHSSP 1642
Score = 31.6 bits (70), Expect = 10.0
Identities = 29/125 (23%), Positives = 48/125 (38%), Gaps = 6/125 (4%)
Query: 703 ASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEP--AVELEPTTETA 760
+ST S + +E S + +D+ V P+ + T P + +E T
Sbjct: 4623 SSTTSGRSEE----STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG 4678
Query: 761 PSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKAD 820
+T+P L+ ST S + S S+ T + + HS+ + P PA
Sbjct: 4679 STTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 4738
Query: 821 SVDVE 825
S VE
Sbjct: 4739 SGLVE 4743
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 59.7 bits (143), Expect = 3e-08
Identities = 59/240 (24%), Positives = 99/240 (41%), Gaps = 37/240 (15%)
Query: 509 SQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQAT 568
S EE+ EE+EE++ E+ E++EEE +EEE+DE+E +E +E+++ + EE EE E
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFE---EEFEEEEGEL 942
Query: 569 PRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRW 628
+ + + + + A A PPPP PP P P +
Sbjct: 943 EEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGA----PPPPTLPPALPPPESPPKVQPE 998
Query: 629 TEEE----MEVAKKGL-VEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHK 683
E E +EV + G E G + A S+ + +++
Sbjct: 999 PEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE-----------------VEREG 1041
Query: 684 QKTSRKPREERDVSQCESVASTVSAQEDED--------IEASNEEENPEDSEVEAVKPSE 735
+ + P + V + S T+ +E ED E EEE ++E EA++ E
Sbjct: 1042 ESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKE 1101
Score = 46.2 bits (108), Expect = 4e-04
Identities = 67/329 (20%), Positives = 111/329 (33%), Gaps = 65/329 (19%)
Query: 599 AAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKS 658
AA PPPP PP P P++ P + LV G G
Sbjct: 834 AAPGPLPPPPPPPPPVPGPVTLPPPQ---------------LVPEGTPGG------GGPP 872
Query: 659 EAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASN 718
+ N + ++ +++ + EE D + E +E+E+ E
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFE 932
Query: 719 EEENPEDSEVEAVKPSEDSPEN-----------ATSRGNTE-------------PAVELE 754
EE E+ E+E + ED E T+ G E P E
Sbjct: 933 EEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESP 992
Query: 755 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAET-AEQMDVDQQEHSAEEGSVCDP 813
P + P P L + +P +E +++ E Q +V+++ S G P
Sbjct: 993 PKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAG----P 1048
Query: 814 PPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPE- 872
PP + V+ E P E + + S+KV+P E + E
Sbjct: 1049 PP---QELVEEEPSAP---------PTLLEEETEDGSDKVQPPPETPAEEEMETETEAEA 1096
Query: 873 -PQSDNDSSATCSADEDVDGEPERQRMFP 900
+ + D +A AD +D P+ ++ P
Sbjct: 1097 LQEKEQDDTAAMLAD-FIDCPPDDEKPPP 1124
Score = 36.2 bits (82), Expect = 0.41
Identities = 62/231 (26%), Positives = 80/231 (34%), Gaps = 43/231 (18%)
Query: 1529 IPAKSPVPGVDPVVSHSPFDP---HHRG-STAGEVYRSHLPTHLDPAMPFHRA---LDPA 1581
+P+ P+P PV S P P +H G S G V +P L P HRA DP
Sbjct: 683 MPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLV---SVPPRLLPGPENHRAGSNEDPI 739
Query: 1582 AAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPD-------VARG 1634
A +P P P + D + ++++L D V G
Sbjct: 740 LAP-----SGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEG 794
Query: 1635 LSPREQPLGLPYPATRGIIDLTNMPPTILVPHPG-----------GTSTPPMDRITYIPG 1683
L P P P AT I T PPT P P G PP +PG
Sbjct: 795 LPPLPPPP--PSGATPPPIAPTG-PPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPG 851
Query: 1684 TQITFPPRPYNSASMSPGHP-------THLAAAASAEREREREREKERERE 1727
PP+ + G P T + +S E E E E E+E E E
Sbjct: 852 PVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEE 902
Score = 31.6 bits (70), Expect = 10.0
Identities = 44/224 (19%), Positives = 84/224 (37%), Gaps = 40/224 (17%)
Query: 29 FPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQQQQQLRRRPSLL-----SEFHPGSDRPQ 83
F ++E ++ E+ + + ++++++L L E G+ P
Sbjct: 921 FEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPP 980
Query: 84 ERRTSYEP------FHPGPSPVDHDSLESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGL 137
+ P P P P LE + P E+ + A PE L
Sbjct: 981 TLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLA---------PEAL 1031
Query: 138 RASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEELIQSMDRVD-------R 190
+ + +++ E+P++ Q +++ ++P L +EE D+V
Sbjct: 1032 PSQGEVEREG------ESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAE 1085
Query: 191 EIAKVEQQILKLKKKQQ-----QLEEEAAKPPEPEKPVSPPPVE 229
E + E + L++K+Q L + PP+ EKP PPP E
Sbjct: 1086 EEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKP--PPPTE 1127
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 59.7 bits (143), Expect = 3e-08
Identities = 77/338 (22%), Positives = 132/338 (39%), Gaps = 30/338 (8%)
Query: 516 EKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTA 575
E +E++ EK E++ +E+++EE++ K D E + + EE E+ E T +
Sbjct: 143 EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGE 202
Query: 576 NSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEV 635
++ + + ++ A A A E+P P P+ PVE E+
Sbjct: 203 EAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPK----SPVE-----EKGKSP 253
Query: 636 AKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERD 695
K VE V K ++ K + + + K K+ P +
Sbjct: 254 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKS---PVPKSP 310
Query: 696 VSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEP 755
V + +S A ++ E+ E+E E + E V+ E+ P++ + E V+ E
Sbjct: 311 VEEAKSKAEVGKGEQKEE----EEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA 366
Query: 756 TTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPP 815
E T S+ V K ++E Q + E+ + S EEGS
Sbjct: 367 VAEVVTITK-SVKVHLEKETKEEGKPLQ-------QEKEKEKAGGEGGSEEEGSDKGAKG 418
Query: 816 ATKAD-SVDVEVRVPENHASKVEGDNTKERDLDRASEK 852
+ K D +V+ EV E +VE TKE+ R EK
Sbjct: 419 SRKEDIAVNGEVEGKE----EVE-QETKEKGSGREEEK 451
Score = 41.2 bits (95), Expect = 0.013
Identities = 93/424 (21%), Positives = 161/424 (37%), Gaps = 36/424 (8%)
Query: 259 PKVELPLYNQPSDTKVYHENIKTNQV------MRKKLILFFKRRNHARKQREQKICQRYD 312
PKVE P K E I+ +V M + L + + K+ +++ + +
Sbjct: 63 PKVEAPKLKVQH--KFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE 120
Query: 313 QLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSAT 372
+ EA E++V ++ + A E K E EK+ E +++ E+++ + Q G S
Sbjct: 121 EEPEAEEEEVAAKKSPVKATAPEVKEEEG-EKEEEEGQEEEEEEDEGAKSDQAEEGGSEK 179
Query: 373 IARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYK 432
SE E E +G +E E ++ E + + + +E P K
Sbjct: 180 EGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKS 239
Query: 433 DRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKS---VPDCVLY------YYLTKK 483
V + + K + K+ + S +E K VP + +
Sbjct: 240 PVPKSPVEEKGKSPVPKSPVEEKGKS-PVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPV 298
Query: 484 NENYKALVRRNYGKRRGRNQQIARPSQ--EEKVEEKEEDKAEKTEKKEEEKKDEEEKDEK 541
E K+ V ++ + ++ + Q EE+ E KE K EK EKKEE+ KD EK +
Sbjct: 299 EEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKA 358
Query: 542 EDSKENTKEKDKIDGTAE-----ETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAA 596
E + + + T E E +E+ P ++ + +G +++ A
Sbjct: 359 ESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKG 418
Query: 597 SAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWA-AIAKMVG 655
S A E + E E EEE KG+V +G + + A K G
Sbjct: 419 SRKEDIAVNGE----VEGKEEVEQETKEKGSGREEE-----KGVVTNGLDLSPADEKKGG 469
Query: 656 TKSE 659
KSE
Sbjct: 470 DKSE 473
Score = 39.3 bits (90), Expect = 0.048
Identities = 68/328 (20%), Positives = 124/328 (37%), Gaps = 48/328 (14%)
Query: 112 EQVSDSHFQRVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNA 171
E+ ++ + V+A P+ PE + +++ + E S Q + +
Sbjct: 120 EEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ-AEEGGSE 178
Query: 172 SPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEA--------AKPPEPEK-- 221
KEE Q + E E + + KK +++ EE A AK +PEK
Sbjct: 179 KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAK 238
Query: 222 -PVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLG----------PKVELPLYNQPS 270
PV PVE+K +S V E + K+ E G K + P+ P
Sbjct: 239 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPV 298
Query: 271 DTKVYHENIKTNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPR 330
+ K K+ K K +++E K + +++ EKK ++ ++ P
Sbjct: 299 EEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV----EKKEEKPKDVPE 354
Query: 331 RKAKESKTRE---------------YYEKQFPEIRKQREQQERFQRVG------QRGAGL 369
+K ES +E + EK+ E K +Q++ ++ G + G+
Sbjct: 355 KKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK 414
Query: 370 SATIARSEH-EISEIIDGLSEQENNEKQ 396
A +R E ++ ++G E E K+
Sbjct: 415 GAKGSRKEDIAVNGEVEGKEEVEQETKE 442
Score = 35.8 bits (81), Expect = 0.53
Identities = 48/222 (21%), Positives = 81/222 (36%), Gaps = 30/222 (13%)
Query: 1837 SKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHS 1896
S+ +E + E E A E++++E+K+ EV + P P
Sbjct: 183 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 242
Query: 1897 SVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSD 1956
E G K P PKS EE +GK+ + + E+G S
Sbjct: 243 KSPVEEKG--KSPVPKSPVEE----KGKSPVPKS---------------PVEEKG--KSP 279
Query: 1957 SSSSLSSHRYETPSDAIEVISPASSPAP--PQEKLQTYQPEVVKANQAENDPTRQYEGPL 2014
S + ++P V A SP P P E+ ++ + EV K Q E + E P
Sbjct: 280 VPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKS-KAEVGKGEQKEEEEKEVKEAPK 338
Query: 2015 HH-YRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHI 2055
++E P + +P +AE + ++T+ +
Sbjct: 339 EEKVEKKEEKP---KDVPEKKKAESPVKEEAVAEVVTITKSV 377
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.126 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 111,018,808
Number of Sequences: 37866
Number of extensions: 6278574
Number of successful extensions: 88781
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 744
Number of HSP's successfully gapped in prelim test: 1404
Number of HSP's that attempted gapping in prelim test: 40098
Number of HSP's gapped (non-prelim): 29935
length of query: 2440
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2321
effective length of database: 13,741,464
effective search space: 31893937944
effective search space used: 31893937944
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.