BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|224177511 sorting nexin 18 isoform c [Homo sapiens] (591 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|224177511 sorting nexin 18 isoform c [Homo sapiens] 1224 0.0 gi|157057543 sorting nexin 18 isoform b [Homo sapiens] 1224 0.0 gi|157057545 sorting nexin 18 isoform a [Homo sapiens] 1122 0.0 gi|23397574 sorting nexin 33 [Homo sapiens] 499 e-141 gi|7706706 sorting nexin 9 [Homo sapiens] 299 6e-81 gi|153791707 sorting nexin family member 30 [Homo sapiens] 71 3e-12 gi|23111055 sorting nexin 7 isoform b [Homo sapiens] 67 4e-11 gi|194294540 sorting nexin 7 isoform a [Homo sapiens] 67 4e-11 gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 64 5e-10 gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 64 5e-10 gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r... 60 7e-09 gi|23943858 sorting nexin 8 [Homo sapiens] 60 7e-09 gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 57 5e-08 gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 57 5e-08 gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 57 5e-08 gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r... 56 1e-07 gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r... 56 1e-07 gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r... 56 1e-07 gi|4507145 sorting nexin 4 [Homo sapiens] 55 2e-07 gi|19224660 protein kinase C and casein kinase substrate in neur... 53 7e-07 gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens] 51 3e-06 gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens] 50 4e-06 gi|24308229 protein kinase C and casein kinase substrate in neur... 50 6e-06 gi|148747351 protein kinase C and casein kinase substrate in neu... 50 6e-06 gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa... 50 6e-06 gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens] 50 6e-06 gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 50 8e-06 gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 50 8e-06 gi|23111026 sorting nexin 11 [Homo sapiens] 50 8e-06 gi|23111028 sorting nexin 11 [Homo sapiens] 50 8e-06 >gi|224177511 sorting nexin 18 isoform c [Homo sapiens] Length = 591 Score = 1224 bits (3166), Expect = 0.0 Identities = 591/591 (100%), Positives = 591/591 (100%) Query: 1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR Sbjct: 1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60 Query: 61 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ Sbjct: 61 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120 Query: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180 Query: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG Sbjct: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240 Query: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL Sbjct: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300 Query: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM Sbjct: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360 Query: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD Sbjct: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420 Query: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL Sbjct: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480 Query: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK Sbjct: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540 Query: 541 GKAWPLEQVIWSVLCRLKGATLTAVPLWVSESYSTGEEASRDVDAWVFSLE 591 GKAWPLEQVIWSVLCRLKGATLTAVPLWVSESYSTGEEASRDVDAWVFSLE Sbjct: 541 GKAWPLEQVIWSVLCRLKGATLTAVPLWVSESYSTGEEASRDVDAWVFSLE 591 >gi|157057543 sorting nexin 18 isoform b [Homo sapiens] Length = 628 Score = 1224 bits (3166), Expect = 0.0 Identities = 591/591 (100%), Positives = 591/591 (100%) Query: 1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR Sbjct: 1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60 Query: 61 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ Sbjct: 61 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120 Query: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180 Query: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG Sbjct: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240 Query: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL Sbjct: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300 Query: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM Sbjct: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360 Query: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD Sbjct: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420 Query: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL Sbjct: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480 Query: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK Sbjct: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540 Query: 541 GKAWPLEQVIWSVLCRLKGATLTAVPLWVSESYSTGEEASRDVDAWVFSLE 591 GKAWPLEQVIWSVLCRLKGATLTAVPLWVSESYSTGEEASRDVDAWVFSLE Sbjct: 541 GKAWPLEQVIWSVLCRLKGATLTAVPLWVSESYSTGEEASRDVDAWVFSLE 591 >gi|157057545 sorting nexin 18 isoform a [Homo sapiens] Length = 624 Score = 1122 bits (2901), Expect = 0.0 Identities = 541/541 (100%), Positives = 541/541 (100%) Query: 1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR Sbjct: 1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60 Query: 61 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ Sbjct: 61 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120 Query: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180 Query: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG Sbjct: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240 Query: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL Sbjct: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300 Query: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM Sbjct: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360 Query: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD Sbjct: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420 Query: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL Sbjct: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480 Query: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK Sbjct: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540 Query: 541 G 541 G Sbjct: 541 G 541 >gi|23397574 sorting nexin 33 [Homo sapiens] Length = 574 Score = 499 bits (1286), Expect = e-141 Identities = 275/548 (50%), Positives = 351/548 (64%), Gaps = 64/548 (11%) Query: 1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60 MAL+ RALYDF SEN EIS+++ E L + SE ++GWL+G NSRG+ GLFPASYV+++R Sbjct: 1 MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60 Query: 61 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120 + G A Y++ P G P A +L PS Sbjct: 61 S--------GISTNHADYSSSPAGS---------------PGAQVSLYNS-----PSVAS 92 Query: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGS-----DDDWDDEWDDSSTVADEP--GALGS 173 P +G GG+ G+ ++QGS DDDWDD WDD TV +EP G LG+ Sbjct: 93 PARSG----GGS----------GFLSNQGSFEEDDDDDWDD-WDDGCTVVEEPRAGGLGT 137 Query: 174 GAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFS 233 +P L+ S GA ++ R L Q + K + V RNLNRFS Sbjct: 138 NGHPPLNLSYP---GAYPSQHMAFRPKPPLER-------QDSLASAKRGSVVGRNLNRFS 187 Query: 234 TFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMK 293 FV+SG EAF+LG+ K + + +GP GP+W+ NP+PF C+++DPTKQTKFKG+K Sbjct: 188 CFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIK 247 Query: 294 SYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRR 353 SYISYKL PTH PV+RRYKHFDWLY RL KF VISVPHLPEKQATGRFEEDFI KR+ Sbjct: 248 SYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRK 307 Query: 354 KGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLST 413 + LI WM+HM SHPVL+Q + FQHFL+C D+K WK GKR+AEKDEMVGA+F LT Sbjct: 308 RRLILWMDHMTSHPVLSQYEGFQHFLSC---LDDKQWKMGKRRAEKDEMVGASFLLTFQI 364 Query: 414 PPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRG 473 P DLQ+VE ++D FK F+KKMDDS LQL+ A+E RK V GF+KE+QK+G +F+ Sbjct: 365 -PTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQA 423 Query: 474 LSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFP 533 +S +F++D S LN AI+ TG Y+AIGE+FAEQP+ DL ++D L+LYQG L+NFP Sbjct: 424 ISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFP 483 Query: 534 DIIHVQKG 541 DIIH+QKG Sbjct: 484 DIIHLQKG 491 >gi|7706706 sorting nexin 9 [Homo sapiens] Length = 595 Score = 299 bits (765), Expect = 6e-81 Identities = 200/557 (35%), Positives = 273/557 (49%), Gaps = 61/557 (10%) Query: 1 MALRARALYDFRSENPG--EISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQV 58 MA +AR +YDF +E PG E+++ E E++++ + GWLEG N +G+RGL P YV++ Sbjct: 1 MATKARVMYDFAAE-PGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEI 59 Query: 59 IRAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPA------SFKPPPDAFQALLQPQ- 111 + + G A + + + + S P A+ A Sbjct: 60 LPSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNW 119 Query: 112 QAPPPSTFQPPGAGF------PYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVA 165 ++ QP GAG P PQ G + G DDDWD++WD Sbjct: 120 ESSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQG---PATGDDDDWDEDWD------ 170 Query: 166 DEPGALGSGAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATV 225 G S + D S SA G A RG S SS+++ Sbjct: 171 ---GPKSSSYFKD---SESADAGGA--------------QRGNS---------RASSSSM 201 Query: 226 SRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTK 285 LN+F F K G E ++L A K +K+ +++G YGP W F C + DP K Sbjct: 202 KIPLNKFPGFAKPGTEQYLL--AKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPRK 259 Query: 286 QTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKF-PVISVPHLPEKQATGRF 344 +K G+KSYI Y+L PT+T V+ RYKHFDWLY RL KF I +P LP+KQ TGRF Sbjct: 260 GSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRF 319 Query: 345 EEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVG 404 EE+FI R + L WM M HPV+++ +VFQ FL + DEK WK GKRKAE+DE+ G Sbjct: 320 EEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFL---NFRDEKEWKTGKRKAERDELAG 376 Query: 405 ANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEY 464 F T+ P A LDL E+E K + FTK MDD +L E ++ KEY Sbjct: 377 VMIFSTME-PEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEY 435 Query: 465 QKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLAL 524 QK+G++ + L+ F LN AI G Y+ I L AEQP++DL +M+ Sbjct: 436 QKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHE 495 Query: 525 YQGHLANFPDIIHVQKG 541 Y+G L FPDII KG Sbjct: 496 YKGFLGCFPDIIGTHKG 512 >gi|153791707 sorting nexin family member 30 [Homo sapiens] Length = 437 Score = 70.9 bits (172), Expect = 3e-12 Identities = 45/124 (36%), Positives = 66/124 (53%), Gaps = 16/124 (12%) Query: 280 IDDPTKQTKFKGMKSYISYKLVPTHTQVP-------VHRRYKHFDWLYARLAEKFPVISV 332 +DDP K M++YI+Y++ T+V V RRY+ FDWL ++L E P + Sbjct: 95 VDDPKKHVCT--METYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLI 152 Query: 333 PHLPE----KQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEK 388 P LPE K RF E+F+ RRK L ++ + HPVL+ + F FLT + D Sbjct: 153 PPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLT---AKDLN 209 Query: 389 AWKQ 392 A+K+ Sbjct: 210 AYKK 213 >gi|23111055 sorting nexin 7 isoform b [Homo sapiens] Length = 336 Score = 67.4 bits (163), Expect = 4e-11 Identities = 41/131 (31%), Positives = 68/131 (51%), Gaps = 19/131 (14%) Query: 279 TIDDPTKQTKFKGMKSYISYKLVPT-------HTQVPVHRRYKHFDWLYARLAEKFPVIS 331 T+D+P ++ ++++I+Y+++ ++ V RRY+ F WL +L E P + Sbjct: 35 TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 92 Query: 332 VPHLPEK----QATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDE 387 +P LPEK RF +DFI RRK L ++N +A HP L + F+ FLT Sbjct: 93 IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA------ 146 Query: 388 KAWKQGKRKAE 398 +AW+ K + Sbjct: 147 QAWELSSHKKQ 157 >gi|194294540 sorting nexin 7 isoform a [Homo sapiens] Length = 451 Score = 67.4 bits (163), Expect = 4e-11 Identities = 41/131 (31%), Positives = 68/131 (51%), Gaps = 19/131 (14%) Query: 279 TIDDPTKQTKFKGMKSYISYKLVPT-------HTQVPVHRRYKHFDWLYARLAEKFPVIS 331 T+D+P ++ ++++I+Y+++ ++ V RRY+ F WL +L E P + Sbjct: 99 TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 156 Query: 332 VPHLPEK----QATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDE 387 +P LPEK RF +DFI RRK L ++N +A HP L + F+ FLT Sbjct: 157 IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA------ 210 Query: 388 KAWKQGKRKAE 398 +AW+ K + Sbjct: 211 QAWELSSHKKQ 221 >gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] Length = 1363 Score = 63.5 bits (153), Expect = 5e-10 Identities = 28/43 (65%), Positives = 33/43 (76%) Query: 498 DAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540 DA++ +GEL A QP Q+LDPVMDLL L QGH N PDIIH+ K Sbjct: 1283 DAFNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHK 1325 >gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] Length = 1366 Score = 63.5 bits (153), Expect = 5e-10 Identities = 28/43 (65%), Positives = 33/43 (76%) Query: 498 DAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540 DA++ +GEL A QP Q+LDPVMDLL L QGH N PDIIH+ K Sbjct: 1286 DAFNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHK 1328 >gi|239745060 PREDICTED: similar to breast cancer anti-estrogen resistance 1 [Homo sapiens] Length = 353 Score = 59.7 bits (143), Expect = 7e-09 Identities = 46/145 (31%), Positives = 76/145 (52%), Gaps = 27/145 (18%) Query: 5 ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60 A+ALYD +E+P E+S R+ +++++ EQD +G WL ++ R +G+ P ++++++ Sbjct: 8 AKALYDNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIMPGNHLKILV 64 Query: 61 AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113 + PAG G PG PA A PG P+P A P +++P PD+ + P +A Sbjct: 65 GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123 Query: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138 +Q PG PSPQ Sbjct: 124 -QQGLYQVPG-----------PSPQ 136 >gi|23943858 sorting nexin 8 [Homo sapiens] Length = 465 Score = 59.7 bits (143), Expect = 7e-09 Identities = 56/247 (22%), Positives = 105/247 (42%), Gaps = 14/247 (5%) Query: 295 YISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRK 354 ++ Y++ + V+RRY F L KFP VP LP K+ G + +FI RR+ Sbjct: 92 HVEYEVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGA-DREFIEARRR 150 Query: 355 GLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTP 414 L ++N +A HP+ ++ V + FL+ S + K E + VG F Sbjct: 151 ALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLK------ESAQCVGDEFLNCKLAT 204 Query: 415 PAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTG------FKKEYQKVG 468 A +++++ + + + +S +L A A + + F KE +G Sbjct: 205 RAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAIG 264 Query: 469 QSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGH 528 L L+ + L QA+ + + + A+Q +Q+ + V++ L L+ Sbjct: 265 SDTTPLPSWAALNSSTWG-SLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDL 323 Query: 529 LANFPDI 535 L ++ D+ Sbjct: 324 LQSYKDL 330 Score = 30.0 bits (66), Expect = 6.2 Identities = 22/63 (34%), Positives = 24/63 (38%), Gaps = 9/63 (14%) Query: 60 RAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTF 119 RA +P PA G A A PPAS P P A + QQ P PS Sbjct: 4 RAMDPLPAAAVGAAAEAEADE---------EADPPASDLPTPQAIEPQAIVQQVPAPSRM 54 Query: 120 QPP 122 Q P Sbjct: 55 QMP 57 >gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] Length = 1415 Score = 57.0 bits (136), Expect = 5e-08 Identities = 26/43 (60%), Positives = 31/43 (72%) Query: 498 DAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540 DA++ +GELFA QP Q+LDPVMDLL L GH DIIH+ K Sbjct: 1335 DAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILDIIHIHK 1377 >gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] Length = 1415 Score = 57.0 bits (136), Expect = 5e-08 Identities = 26/43 (60%), Positives = 31/43 (72%) Query: 498 DAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540 DA++ +GELFA QP Q+LDPVMDLL L GH DIIH+ K Sbjct: 1335 DAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILDIIHIHK 1377 >gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] Length = 870 Score = 57.0 bits (136), Expect = 5e-08 Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 27/145 (18%) Query: 5 ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQV-I 59 A+ALYD +E+P E+S R+ +++++ EQD +G WL ++ R +G+ P + +++ + Sbjct: 8 AKALYDNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNRLKILV 64 Query: 60 RAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113 + PAG GPG PA A PG P P A P +++P PD+ + P +A Sbjct: 65 GMYDKKPAGP-GPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123 Query: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138 +Q PG PSPQ Sbjct: 124 -QQGLYQVPG-----------PSPQ 136 >gi|239756225 PREDICTED: similar to breast cancer anti-estrogen resistance 1 [Homo sapiens] Length = 232 Score = 55.8 bits (133), Expect = 1e-07 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%) Query: 5 ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60 A+ALY +E+P E+S R+ +++++ EQD +G WL ++ R +G+ P ++++++ Sbjct: 8 AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64 Query: 61 AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113 + PAG G PG PA A PG P+P A P +++P PD+ + P +A Sbjct: 65 GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123 Query: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138 +Q PG PSPQ Sbjct: 124 -QQGLYQVPG-----------PSPQ 136 >gi|239750776 PREDICTED: similar to breast cancer anti-estrogen resistance 1 [Homo sapiens] Length = 224 Score = 55.8 bits (133), Expect = 1e-07 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%) Query: 5 ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60 A+ALY +E+P E+S R+ +++++ EQD +G WL ++ R +G+ P ++++++ Sbjct: 8 AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64 Query: 61 AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113 + PAG G PG PA A PG P+P A P +++P PD+ + P +A Sbjct: 65 GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123 Query: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138 +Q PG PSPQ Sbjct: 124 -QQGLYQVPG-----------PSPQ 136 >gi|239745044 PREDICTED: similar to breast cancer anti-estrogen resistance 1 [Homo sapiens] Length = 368 Score = 55.8 bits (133), Expect = 1e-07 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%) Query: 5 ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60 A+ALY +E+P E+S R+ +++++ EQD +G WL ++ R +G+ P ++++++ Sbjct: 8 AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64 Query: 61 AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113 + PAG G PG PA A PG P+P A P +++P PD+ + P +A Sbjct: 65 GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123 Query: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138 +Q PG PSPQ Sbjct: 124 -QQGLYQVPG-----------PSPQ 136 >gi|4507145 sorting nexin 4 [Homo sapiens] Length = 450 Score = 55.1 bits (131), Expect = 2e-07 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 8/126 (6%) Query: 311 RRYKHFDWLYARLAEKFPVISVPHLPEKQA--------TGRFEEDFISKRRKGLIWWMNH 362 RRY F+ L + L +P I VP LPEK+A + DF+ +RR GL ++ Sbjct: 105 RRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLR 164 Query: 363 MASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQ 422 +ASHP+L + +F FLT + E + G + + N + P DL+ Sbjct: 165 IASHPILCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLK 224 Query: 423 EVESKI 428 ++ Sbjct: 225 HYSDEL 230 >gi|19224660 protein kinase C and casein kinase substrate in neurons 3 [Homo sapiens] Length = 424 Score = 53.1 bits (126), Expect = 7e-07 Identities = 25/59 (42%), Positives = 36/59 (61%) Query: 3 LRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRA 61 +R RALYD+ + E+S R E L SE+D +GW +G G GL+PA+YV+ + A Sbjct: 366 VRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVECVGA 424 >gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens] Length = 347 Score = 50.8 bits (120), Expect = 3e-06 Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 2/54 (3%) Query: 6 RALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVI 59 R LYDF EN GE+ +E ++++L ++ D E W EG+ G+ G FP +YV+VI Sbjct: 291 RGLYDFEPENQGELGFKEGDIITLTNQID-ENWYEGM-IHGESGFFPINYVEVI 342 >gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens] Length = 352 Score = 50.4 bits (119), Expect = 4e-06 Identities = 24/56 (42%), Positives = 37/56 (66%), Gaps = 2/56 (3%) Query: 6 RALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRA 61 RALYDF EN GE+ +E ++++L ++ D E W EG+ G G FP +YV+++ A Sbjct: 296 RALYDFEPENEGELGFKEGDIITLTNQID-ENWYEGM-LHGHSGFFPINYVEILVA 349 >gi|24308229 protein kinase C and casein kinase substrate in neurons 1 [Homo sapiens] Length = 444 Score = 50.1 bits (118), Expect = 6e-06 Identities = 22/57 (38%), Positives = 34/57 (59%) Query: 3 LRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVI 59 +R RALYD+ + E+S + + L+ E+D +GW G G GL+PA+YV+ I Sbjct: 388 VRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI 444 >gi|148747351 protein kinase C and casein kinase substrate in neurons 2 [Homo sapiens] Length = 486 Score = 50.1 bits (118), Expect = 6e-06 Identities = 21/58 (36%), Positives = 36/58 (62%) Query: 3 LRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60 +R RALYD+ + E+S + + L+ ++D +GW +G G GL+PA+YV+ I+ Sbjct: 429 VRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486 >gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sapiens] Length = 561 Score = 50.1 bits (118), Expect = 6e-06 Identities = 43/140 (30%), Positives = 62/140 (44%), Gaps = 24/140 (17%) Query: 5 ARALYDFRSENPGEISLREHEVLSLCSEQ---DIEGWLEGVNSRGDRGLFPASYVQVIRA 61 ARALYD +E+P E+S R +VL + + ++GW + G +G+ PA+ V+++ A Sbjct: 10 ARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCL-CSLHGQQGIVPANRVKLLPA 68 Query: 62 PEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQP 121 GPA P P A P S P PD + PPP+ Sbjct: 69 ---GPA--------------PKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPAR-PC 110 Query: 122 PGAGFPYGGGALQPSPQQLY 141 P +G P G PSP +Y Sbjct: 111 PTSGPP--AGPCPPSPDLIY 128 >gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens] Length = 368 Score = 50.1 bits (118), Expect = 6e-06 Identities = 25/54 (46%), Positives = 35/54 (64%), Gaps = 2/54 (3%) Query: 6 RALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVI 59 +ALYDF EN GE+ E +V++L ++ D E W EG+ G G FP SYV+V+ Sbjct: 312 KALYDFEPENDGELGFHEGDVITLTNQID-ENWYEGMLD-GQSGFFPLSYVEVL 363 >gi|23111036 sorting nexin 1 isoform c [Homo sapiens] Length = 474 Score = 49.7 bits (117), Expect = 8e-06 Identities = 72/291 (24%), Positives = 113/291 (38%), Gaps = 61/291 (20%) Query: 268 EWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVP--------VHRRYKHFDWL 319 E QE+ + I DP K GM +Y++YK V T T +P V RR+ F L Sbjct: 137 EEQEDQFDLTVGITDPEKIGD--GMNAYVAYK-VTTQTSLPLFRSKQFAVKRRFSDFLGL 193 Query: 320 YARLAEKFPV--ISVPHLPEKQATGRFE----------EDFISKRRKGLIWWMNHMASHP 367 Y +L+EK VP PEK G + +F+ KRR L ++ + +HP Sbjct: 194 YEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHP 253 Query: 368 VLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESK 427 + Q + FL EK+E+ A TLS A L L+ Sbjct: 254 TMLQDPDVREFL------------------EKEELPRAVGTQTLS---GAGL-LKMFNKA 291 Query: 428 IDGFKCFTKKMDDSALQLNHTANEFARKQ------------VTGFKKEYQ-KVGQSFRGL 474 D T KM++S + E ++ + +KE Q + L Sbjct: 292 TDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSL 351 Query: 475 SQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALY 525 + L + L++A++ + + I +L EQ D + +LL+ Y Sbjct: 352 AM---LGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDY 399 >gi|23111034 sorting nexin 1 isoform a [Homo sapiens] Length = 522 Score = 49.7 bits (117), Expect = 8e-06 Identities = 72/291 (24%), Positives = 113/291 (38%), Gaps = 61/291 (20%) Query: 268 EWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVP--------VHRRYKHFDWL 319 E QE+ + I DP K GM +Y++YK V T T +P V RR+ F L Sbjct: 137 EEQEDQFDLTVGITDPEKIGD--GMNAYVAYK-VTTQTSLPLFRSKQFAVKRRFSDFLGL 193 Query: 320 YARLAEKFPV--ISVPHLPEKQATGRFE----------EDFISKRRKGLIWWMNHMASHP 367 Y +L+EK VP PEK G + +F+ KRR L ++ + +HP Sbjct: 194 YEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHP 253 Query: 368 VLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESK 427 + Q + FL EK+E+ A TLS A L L+ Sbjct: 254 TMLQDPDVREFL------------------EKEELPRAVGTQTLS---GAGL-LKMFNKA 291 Query: 428 IDGFKCFTKKMDDSALQLNHTANEFARKQ------------VTGFKKEYQ-KVGQSFRGL 474 D T KM++S + E ++ + +KE Q + L Sbjct: 292 TDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSL 351 Query: 475 SQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALY 525 + L + L++A++ + + I +L EQ D + +LL+ Y Sbjct: 352 AM---LGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDY 399 >gi|23111026 sorting nexin 11 [Homo sapiens] Length = 270 Score = 49.7 bits (117), Expect = 8e-06 Identities = 41/136 (30%), Positives = 57/136 (41%), Gaps = 11/136 (8%) Query: 268 EWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVP--------VHRRYKHFDWL 319 E QE + DP Q + SY+ YK+ HT V RRY+ F WL Sbjct: 9 ENQEQEEVITVRVQDPRVQNE-GSWNSYVDYKIF-LHTNSKAFTAKTSCVRRRYREFVWL 66 Query: 320 YARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFL 379 +L ++ VP LP K ++FI KRR+GL ++ + VL FL Sbjct: 67 RKQLQRNAGLVPVPELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFL 126 Query: 380 TCPSSTDE-KAWKQGK 394 S E +A QG+ Sbjct: 127 QSQLSVPEIEACVQGR 142 >gi|23111028 sorting nexin 11 [Homo sapiens] Length = 270 Score = 49.7 bits (117), Expect = 8e-06 Identities = 41/136 (30%), Positives = 57/136 (41%), Gaps = 11/136 (8%) Query: 268 EWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVP--------VHRRYKHFDWL 319 E QE + DP Q + SY+ YK+ HT V RRY+ F WL Sbjct: 9 ENQEQEEVITVRVQDPRVQNE-GSWNSYVDYKIF-LHTNSKAFTAKTSCVRRRYREFVWL 66 Query: 320 YARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFL 379 +L ++ VP LP K ++FI KRR+GL ++ + VL FL Sbjct: 67 RKQLQRNAGLVPVPELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFL 126 Query: 380 TCPSSTDE-KAWKQGK 394 S E +A QG+ Sbjct: 127 QSQLSVPEIEACVQGR 142 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.135 0.419 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,986,586 Number of Sequences: 37866 Number of extensions: 1690962 Number of successful extensions: 11734 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 193 Number of HSP's successfully gapped in prelim test: 720 Number of HSP's that attempted gapping in prelim test: 8091 Number of HSP's gapped (non-prelim): 3242 length of query: 591 length of database: 18,247,518 effective HSP length: 108 effective length of query: 483 effective length of database: 14,157,990 effective search space: 6838309170 effective search space used: 6838309170 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.