Guide to the Human Genome
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Search of human proteins with 224028244

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224028244 non-POU domain containing, octamer-binding isoform
1 [Homo sapiens]
         (471 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224028246 non-POU domain containing, octamer-binding isoform ...   956   0.0  
gi|224028244 non-POU domain containing, octamer-binding isoform ...   956   0.0  
gi|34932414 non-POU domain containing, octamer-binding isoform 1...   956   0.0  
gi|224028248 non-POU domain containing, octamer-binding isoform ...   767   0.0  
gi|109240550 paraspeckle protein 1 [Homo sapiens]                     541   e-154
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...   515   e-146
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    74   4e-13
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]      72   8e-13
gi|148746195 trichohyalin [Homo sapiens]                               70   5e-12
gi|123173757 RAVER1 [Homo sapiens]                                     69   1e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    67   3e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    67   3e-11
gi|56549694 enabled homolog isoform a [Homo sapiens]                   66   6e-11
gi|39930375 enabled homolog isoform b [Homo sapiens]                   66   6e-11
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    66   8e-11
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    65   1e-10
gi|13899354 RNA binding motif protein 4B [Homo sapiens]                65   2e-10
gi|93277122 RNA binding motif protein 4 [Homo sapiens]                 64   2e-10
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    64   3e-10
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]                      64   3e-10
gi|38201714 ELAV-like 1 [Homo sapiens]                                 64   3e-10
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]                      64   3e-10
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]                      64   3e-10
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]                      64   3e-10
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]                      64   3e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    63   5e-10
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]      63   5e-10
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila...    63   7e-10
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s...    62   9e-10
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora...    61   3e-09

>gi|224028246 non-POU domain containing, octamer-binding isoform 1
           [Homo sapiens]
          Length = 471

 Score =  956 bits (2471), Expect = 0.0
 Identities = 471/471 (100%), Positives = 471/471 (100%)

Query: 1   MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK 60
           MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
Sbjct: 1   MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK 60

Query: 61  NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT 120
           NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
Sbjct: 61  NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT 120

Query: 121 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI 180
           LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
Sbjct: 121 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI 180

Query: 181 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL 240
           VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
Sbjct: 181 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL 240

Query: 241 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM 300
           VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
Sbjct: 241 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM 300

Query: 301 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE 360
           EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
Sbjct: 301 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE 360

Query: 361 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM 420
           EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
Sbjct: 361 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM 420

Query: 421 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY 471
           PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
Sbjct: 421 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY 471


>gi|224028244 non-POU domain containing, octamer-binding isoform 1
           [Homo sapiens]
          Length = 471

 Score =  956 bits (2471), Expect = 0.0
 Identities = 471/471 (100%), Positives = 471/471 (100%)

Query: 1   MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK 60
           MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
Sbjct: 1   MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK 60

Query: 61  NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT 120
           NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
Sbjct: 61  NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT 120

Query: 121 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI 180
           LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
Sbjct: 121 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI 180

Query: 181 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL 240
           VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
Sbjct: 181 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL 240

Query: 241 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM 300
           VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
Sbjct: 241 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM 300

Query: 301 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE 360
           EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
Sbjct: 301 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE 360

Query: 361 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM 420
           EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
Sbjct: 361 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM 420

Query: 421 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY 471
           PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
Sbjct: 421 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY 471


>gi|34932414 non-POU domain containing, octamer-binding isoform 1
           [Homo sapiens]
          Length = 471

 Score =  956 bits (2471), Expect = 0.0
 Identities = 471/471 (100%), Positives = 471/471 (100%)

Query: 1   MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK 60
           MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
Sbjct: 1   MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK 60

Query: 61  NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT 120
           NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
Sbjct: 61  NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT 120

Query: 121 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI 180
           LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
Sbjct: 121 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI 180

Query: 181 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL 240
           VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
Sbjct: 181 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL 240

Query: 241 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM 300
           VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
Sbjct: 241 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM 300

Query: 301 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE 360
           EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
Sbjct: 301 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE 360

Query: 361 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM 420
           EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
Sbjct: 361 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM 420

Query: 421 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY 471
           PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
Sbjct: 421 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY 471


>gi|224028248 non-POU domain containing, octamer-binding isoform 2
           [Homo sapiens]
          Length = 382

 Score =  767 bits (1980), Expect = 0.0
 Identities = 382/382 (100%), Positives = 382/382 (100%)

Query: 90  MRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSAS 149
           MRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSAS
Sbjct: 1   MRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSAS 60

Query: 150 LTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCS 209
           LTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCS
Sbjct: 61  LTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCS 120

Query: 210 EGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAM 269
           EGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAM
Sbjct: 121 EGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAM 180

Query: 270 RWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEEL 329
           RWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEEL
Sbjct: 181 RWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEEL 240

Query: 330 HNQEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAM 389
           HNQEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAM
Sbjct: 241 HNQEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAM 300

Query: 390 GGAMGINNRGAMPPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGG 449
           GGAMGINNRGAMPPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGG
Sbjct: 301 GGAMGINNRGAMPPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGG 360

Query: 450 TPPAFNRAAPGAEFAPNKRRRY 471
           TPPAFNRAAPGAEFAPNKRRRY
Sbjct: 361 TPPAFNRAAPGAEFAPNKRRRY 382


>gi|109240550 paraspeckle protein 1 [Homo sapiens]
          Length = 523

 Score =  541 bits (1393), Expect = e-154
 Identities = 287/482 (59%), Positives = 342/482 (70%), Gaps = 50/482 (10%)

Query: 37  PPPPIPANGQQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEK 96
           P PP PA  +    +  G TID+K+F KPGEKT+TQR RLFVGNLP DITEE+ ++LFE+
Sbjct: 45  PAPPAPAPPEDHPDEEMGFTIDIKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFER 104

Query: 97  YGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLP 156
           YG+  EVFI++D+GFGFIRLE+RTLAEIAK ELD   L+ + LR+RFA H A+LTV+NL 
Sbjct: 105 YGEPSEVFINRDRGFGFIRLESRTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLS 164

Query: 157 QYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLT 216
             VSNELLE+AFS FG VE+AVV+VDDRGR +GKG VEF+ KP ARKAL+RC +G+FLLT
Sbjct: 165 PVVSNELLEQAFSQFGPVEKAVVVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLT 224

Query: 217 TFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIE 276
           T PRPV VEPM+Q DDE+GLPEKL+ K QQ+HKEREQPPRFAQPG+FE+EYA RWKAL E
Sbjct: 225 TTPRPVIVEPMEQFDDEDGLPEKLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDE 284

Query: 277 MEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQK 336
           MEKQQ++QVDRNI+EA+EKLE EMEAARHEHQ+MLMRQDLMRRQEELRR+EEL NQE+QK
Sbjct: 285 MEKQQREQVDRNIREAKEKLEAEMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQK 344

Query: 337 RKQLELRQEEERRRREEEM-RRQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGI 395
           RKQ++LR EEE RRREEEM R +++E +RRQQEGFK  + + REQE+RMG M   GA  I
Sbjct: 345 RKQIQLRHEEEHRRREEEMIRHREQEELRRQQEGFKPNYMENREQEMRMGDMGPRGA--I 402

Query: 396 NNRGAMPPAPVP------------------AGTPAPPGPATMMPDGTLGLTPPT------ 431
           N   A  PAP                     G P  PGPA M P+G   +  P       
Sbjct: 403 NMGDAFSPAPAGNQGPPPMMGMNMNNRATIPGPPMGPGPA-MGPEGAANMGTPMMPDNGA 461

Query: 432 --TERFGQA-------------------ATMEGIGAIGGTPPAFNRAAPGAEF-APNKRR 469
              +RF Q                    A M G+G + G P  F R + G  F  PNKRR
Sbjct: 462 VHNDRFPQGPPSQMGSPMGSRTGSETPQAPMSGVGPVSGGPGGFGRGSQGGNFEGPNKRR 521

Query: 470 RY 471
           RY
Sbjct: 522 RY 523


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score =  515 bits (1327), Expect = e-146
 Identities = 284/475 (59%), Positives = 346/475 (72%), Gaps = 27/475 (5%)

Query: 16  PRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPGEKTFTQRSR 75
           PR   QHH    +HQQ  Q PPP       ++  S +EG   +L   R+PGEKT+TQR R
Sbjct: 241 PRGGRQHH--PPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCR 298

Query: 76  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLR 135
           LFVGNLP DITE+E ++LF KYG+ GEVFI+K KGFGFI+LE+R LAEIAK ELD+ P+R
Sbjct: 299 LFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMR 358

Query: 136 GKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEF 195
           G+QLRVRFA H+A+L+VRNL  YVSNELLEEAFS FG +ERAVVIVDDRGR +GKGIVEF
Sbjct: 359 GRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEF 418

Query: 196 SGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPP 255
           + KPAARKA +RCSEG FLLTT PRPV VEP++QLDDE+GLPEKL  KN  + KERE PP
Sbjct: 419 ASKPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPP 478

Query: 256 RFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQD 315
           RFAQ G+FEYEY+ RWK+L EMEKQQ++QV++N+K+A++KLE EME A HEHQ  L+RQD
Sbjct: 479 RFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQD 538

Query: 316 LMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM---RRQQEEMMRRQQEG--F 370
           LMRRQEELRRMEELHNQE+QKRK+++LRQEEERRRREEEM   +R+ EE MRRQ+E    
Sbjct: 539 LMRRQEELRRMEELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYS 598

Query: 371 KGTFPDAREQEIRMGQMAMGGAMGINN---RGAMPPAPVPA----GTPAPPG--PATMMP 421
           +  + D RE+++RMG    GGAM + +    G     P+      G  A PG  PATM  
Sbjct: 599 RMGYMDPRERDMRMGG---GGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATM-- 653

Query: 422 DGTLGLTPPTTERFGQ--AATMEGIGAIG---GTPPAFNRAAPGAEFAPNKRRRY 471
            G++  +   TERFGQ  A  + G G  G   GTP  + R     E  PNK+ R+
Sbjct: 654 SGSMMGSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYE-GPNKKPRF 707



 Score = 32.7 bits (73), Expect = 0.73
 Identities = 21/64 (32%), Positives = 22/64 (34%), Gaps = 3/64 (4%)

Query: 402 PPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGA 461
           PP   P  TP PP   T  P G     PPT    G   T    G     P A     PG 
Sbjct: 142 PPGSGPGPTPTPPPAVTSAPPGA---PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGP 198

Query: 462 EFAP 465
           +  P
Sbjct: 199 KQGP 202



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%)

Query: 400 AMPPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAP 459
           A  P P P    APP  ++  P      TPPT+     A    G G     PPA   A P
Sbjct: 112 AQGPGPAPGVGSAPPASSSAPP-----ATPPTSG----APPGSGPGPTPTPPPAVTSAPP 162

Query: 460 GA 461
           GA
Sbjct: 163 GA 164



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 14/25 (56%), Positives = 14/25 (56%), Gaps = 3/25 (12%)

Query: 16  PRKHHQHHHQQQHHQQQQQQPPPPP 40
           P  H    H Q H   QQQQPPPPP
Sbjct: 82  PPPHQPPPHPQPH---QQQQPPPPP 103


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 46/163 (28%), Positives = 84/163 (51%), Gaps = 3/163 (1%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E   Q+ ++EG   +   + Q   +E +   +  Q G  E +   + + + + E+Q  +Q
Sbjct: 168 EQEGQVREQEGQVREQ--EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE-LHNQEVQKRKQLELR 343
            ++  K+  +  E E +  + E QV    + + +++E++R  EE +  QE Q  KQ E  
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285

Query: 344 QEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
           ++EE+   +EE  R+QEE MR Q+E  +      REQE +MG+
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328



 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 49/162 (30%), Positives = 92/162 (56%), Gaps = 7/162 (4%)

Query: 228 DQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDR 287
           +Q+ ++E   E++  + +Q  K++EQ  +  Q G  E +   + + + E E+Q ++Q + 
Sbjct: 262 EQMREQE---EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ-EE 317

Query: 288 NIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEEL--RRMEELHNQEVQKRKQLE-LRQ 344
            ++E  E++  + E    + + M  +++ M +QEE    + E++  QE Q RKQ E +R+
Sbjct: 318 QMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377

Query: 345 EEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
           +EE+ R++EE  R+QEE M  Q+E         REQE +MG+
Sbjct: 378 QEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGE 419



 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 46/172 (26%), Positives = 92/172 (53%), Gaps = 10/172 (5%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E M + +++ G  E+ V K ++  +++E+  R  +    E E  MR +    +++++Q +
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEEL---------RRMEELHNQEVQ 335
            +    E  E++  + E  R + + M  +++ MR QEE           + E++  Q+ Q
Sbjct: 287 QEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ 346

Query: 336 KRKQLE-LRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
             KQ E + ++EE+ +++EE  R+QEE MR+Q+E  +      R+QE +MG+
Sbjct: 347 MWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 41/149 (27%), Positives = 77/149 (51%), Gaps = 11/149 (7%)

Query: 225 EPMDQLDDEEGL----PEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQ 280
           E   Q+ ++EG      E++  + +Q  K+ EQ       G  E +   + + + E E+Q
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQM------GEQEEQMRKQEEQMGEQEEQ 242

Query: 281 QQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQL 340
            Q Q ++  K+  +  + E +    E Q+    + +++++E+  + E+   QE Q R+Q 
Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302

Query: 341 ELRQEEERRRRE-EEMRRQQEEMMRRQQE 368
           E  +E+E + RE EE  R+QEE M +Q+E
Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEE 331



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 35/146 (23%), Positives = 81/146 (55%), Gaps = 7/146 (4%)

Query: 223 TVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQ 282
           T E  +Q+ ++E   E++  + +Q  ++ EQ     +    + E     K  +  +K+Q 
Sbjct: 291 TGEQEEQMREQE---EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQM 347

Query: 283 DQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLEL 342
            + +  + E  E+++ + E  R + + M  +++ MR+QEE  R +E   +++ ++K+ ++
Sbjct: 348 WKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQE---EQMGEQKE-QM 403

Query: 343 RQEEERRRREEEMRRQQEEMMRRQQE 368
            +++E+ R +EE   +Q+E MR+Q+E
Sbjct: 404 GEQKEQMREQEEQMGEQKEQMRKQEE 429



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 44/166 (26%), Positives = 81/166 (48%), Gaps = 10/166 (6%)

Query: 232 DEEGLPEKLVIKNQQFH-KEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
           D+  LP++  ++ Q+   +E+E   R  +    E E  +R     E E Q ++Q  +  +
Sbjct: 44  DKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR-----EQEGQVREQEGQVRE 98

Query: 291 EAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRME-ELHNQEVQKRKQL-ELRQEEER 348
           +  +  E E +    E QV      +  ++ ++R  E ++  QE Q R+Q  ++R++E +
Sbjct: 99  QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 158

Query: 349 RRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMG 394
            R +E   R+QE  +R Q+   +      REQE +MG+    G MG
Sbjct: 159 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQE--GQMG 202



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 16/127 (12%)

Query: 276 EMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRME-ELHNQEV 334
           E E Q ++Q  +  ++  +  E E +    E QV      +  ++ ++R  E ++  QE 
Sbjct: 112 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 171

Query: 335 QKRKQLELRQEEERRRRE---------------EEMRRQQEEMMRRQQEGFKGTFPDARE 379
           Q R+Q    +E+E + RE               EE   +QEE M++Q+E         R+
Sbjct: 172 QVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRK 231

Query: 380 QEIRMGQ 386
           QE +MG+
Sbjct: 232 QEEQMGE 238



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 29/107 (27%), Positives = 57/107 (53%), Gaps = 19/107 (17%)

Query: 275 IEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEV 334
           +++ + ++ ++  +IKE + KLE +        ++ L ++  +R QE      ++  QE 
Sbjct: 20  LQLVETEKSEIQLHIKELKRKLETD--------KIPLPQEGQVREQEG-----QVREQEG 66

Query: 335 QKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
           Q R+Q    +E+E + RE+E + +++E   R+QEG        REQE
Sbjct: 67  QVREQEGQVREQEGQVREQEGQVREQEGQVREQEG------QVREQE 107



 Score = 36.2 bits (82), Expect = 0.066
 Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 11/101 (10%)

Query: 286 DRNIKEAREKLEMEMEAARHEH-QVMLMRQDLMRRQEE----LRRMEELHNQEVQKRKQL 340
           +  +KE   +L+ E++    E  ++ L  ++L R+ E     L +  ++  QE Q R+Q 
Sbjct: 6   NEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65

Query: 341 ELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
              +E+E + RE+E + +++E   R+QEG        REQE
Sbjct: 66  GQVREQEGQVREQEGQVREQEGQVREQEG------QVREQE 100


>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
          Length = 382

 Score = 72.4 bits (176), Expect = 8e-13
 Identities = 56/181 (30%), Positives = 90/181 (49%), Gaps = 37/181 (20%)

Query: 62  FRKPGEKTFTQRSR-------LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD-----K 109
           F+ P E+    R+R       +FV N+  DI +E++++LF +YG    V + +D     K
Sbjct: 180 FKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSK 239

Query: 110 GFGFIRLETRTLAEIAKVELDNMPLRGK---------------QLRVRF---------AC 145
           GFGF+R ET   A+ A ++L    + GK               +LR RF           
Sbjct: 240 GFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRP 299

Query: 146 HSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKAL 205
               + ++NL + +++E L+E FS FG + RA V++ + G+  G G+V FS    A KA+
Sbjct: 300 PGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMM-EVGQGKGFGVVCFSSFEEATKAV 358

Query: 206 D 206
           D
Sbjct: 359 D 359



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 41/154 (26%), Positives = 69/154 (44%), Gaps = 15/154 (9%)

Query: 66  GEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDK------GFGFIRLETR 119
           G+K    ++ L+VG+L PD+TE+ + K F   G      I +D       G+G++     
Sbjct: 10  GKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFP 69

Query: 120 TLAEIAKVELDNMPLRGKQLRVRFA--------CHSASLTVRNLPQYVSNELLEEAFSVF 171
             AE A   ++   + GK  R+ ++            ++ ++NL + + N  L   FS F
Sbjct: 70  ADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAF 129

Query: 172 GQVERAVVIVDDRGRPSGKGIVEFSGKPAARKAL 205
           G +    V+ DD G   G   V F    AA +A+
Sbjct: 130 GNILSCKVVCDDNG-SKGYAYVHFDSLAAANRAI 162


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 55/175 (31%), Positives = 96/175 (54%), Gaps = 24/175 (13%)

Query: 228 DQLDDEEGLPEKLVIK-NQQFHKEREQPPRFAQPGSFEYEYAMRWKALI-----EMEKQQ 281
           ++  DEE L  + +++  ++  +E++Q  R  Q   F+ E    W+        E EK Q
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261

Query: 282 QD--QVDRNIKEAREKL-EMEMEAARHEHQVMLMRQDLMRRQEELRRM--EELHNQEVQK 336
           ++  Q  R ++E  E+L ++E +  R E Q    +Q  +RR+++LRR   EE   Q+ ++
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321

Query: 337 RKQLELRQEEERRR-----REEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
           R+Q E R+++E RR     RE+E RR+Q+  +RR+QE       + REQ++R  Q
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQ--LRREQE------EERREQQLRREQ 368



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 42/171 (24%), Positives = 90/171 (52%), Gaps = 16/171 (9%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
           +++E    + V++ ++   + E+P R  +    E +     +  +  E+Q+++Q  + ++
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301

Query: 291 -----------EAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQ 339
                      E RE+ E   E      Q    R+  +RR++E RR ++L  ++ ++R++
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE 361

Query: 340 LELRQEEERRRREEEMRRQQ----EEMMRRQQEGFKGTFPDAREQEIRMGQ 386
            +LR+E+E  RRE+++RR+Q    E+ +RR+Q+  +      REQ++R  Q
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQ-LRREQQLRREQQLRREQ 411



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 48/165 (29%), Positives = 86/165 (52%), Gaps = 8/165 (4%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           EP  Q + +E   +   ++ Q+  +ER++  +  Q      E  +R K   E E+++Q +
Sbjct: 264 EPQRQRELQEEEEQLRKLERQELRRERQEEEQ--QQQRLRREQQLRRKQ--EEERREQQE 319

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQ 344
             R  +E RE+ E   E      Q     Q L R QEE RR ++L  ++ ++R++ +LR+
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379

Query: 345 EEERRRREEEMRRQQ---EEMMRRQQEGFKGTFPDAREQEIRMGQ 386
           E++ RR ++  R QQ   E+ +RR+Q+  +      REQ++R  Q
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQ-LRREQQLRREQQLRREQ 423



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 40/154 (25%), Positives = 83/154 (53%), Gaps = 11/154 (7%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           ++L  K ++  +E+++  R  Q    + E     +   E E++++ Q+ R  +E R + +
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363

Query: 298 MEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERR-----RRE 352
           +  E      +  L R+  +RR+++LRR ++L  ++ Q R++ +LR+E++ R     RRE
Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRRE 422

Query: 353 EEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
           +++RR+QEE    Q+        + REQ ++  Q
Sbjct: 423 QQLRREQEEERHEQKHE-----QERREQRLKREQ 451



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 56/159 (35%), Positives = 86/159 (54%), Gaps = 16/159 (10%)

Query: 238 EKLVIKNQQFHKE----REQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAR 293
           E+ + + QQ  +E    REQ  R  Q    E E   R +   E E+++Q ++ R  +E R
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEE-RHEQKHEQERREQ-RLKREQEERR 455

Query: 294 EKLEMEMEAARHEHQVMLMRQDLMRRQEELRR-----MEELHNQEVQKRKQLELRQEEER 348
           + L+ E E  RHE +    +Q L R QEE RR     +EE   +E Q+R++ +LR+E+E 
Sbjct: 456 DWLKREEETERHEQE--RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE- 512

Query: 349 RRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQM 387
            RRE+ ++RQ+EE   R Q+  +      REQE R  Q+
Sbjct: 513 ERREQRLKRQEEE--ERLQQRLRSEQQLRREQEERREQL 549



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 43/146 (29%), Positives = 83/146 (56%), Gaps = 17/146 (11%)

Query: 233 EEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEA 292
           EE   ++ + + QQ  +++E+  R  Q    E +         + E++++ Q+ R  +E 
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE-----QQEERREQQLRREQEER 346

Query: 293 REK-LEMEMEAARHEHQVML-----MRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEE 346
           RE+ L  E E  R E Q+        R+  +RR+++LRR ++L  ++ Q R++ +LR+E+
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ-QLRREQQLRREQ 405

Query: 347 ERRRREEEMRRQQ----EEMMRRQQE 368
           +  RRE+++RR+Q    E+ +RR+QE
Sbjct: 406 Q-LRREQQLRREQQLRREQQLRREQE 430



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 41/137 (29%), Positives = 77/137 (56%), Gaps = 8/137 (5%)

Query: 238  EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
            E+   K ++  +E EQ  R  +P     +   R     E  +Q+++Q+ R  +E R + E
Sbjct: 1077 ERQYRKEEELQQEEEQLLR-EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135

Query: 298  MEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQ-----EVQKRKQLELRQEEERRRRE 352
            +E +  R E +V    + L+R + E RR +EL  Q     E+Q+ ++  LR+E+E+RR+E
Sbjct: 1136 LERQY-REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194

Query: 353  EEMR-RQQEEMMRRQQE 368
             E + R++EE+ R++++
Sbjct: 1195 RERQYREEEELQRQKRK 1211



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 45/151 (29%), Positives = 83/151 (54%), Gaps = 15/151 (9%)

Query: 243 KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALI-EMEKQQQDQVDRNIKEAREKLEMEME 301
           + QQ  +E+E+  R  Q    E E   R + L  E E+++++Q  R  ++ R + ++  E
Sbjct: 335 REQQLRREQEE--RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392

Query: 302 AARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEE--ERRRREEEMRRQQ 359
                 Q  L R+  +RR+++LRR ++L  ++  +R+Q E R E+  E+ RRE+ ++R+Q
Sbjct: 393 QQLRREQ-QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451

Query: 360 EEM---MRRQQEGFKGTFPDAREQEIRMGQM 387
           EE    ++R++E       +  EQE R  Q+
Sbjct: 452 EERRDWLKREEE------TERHEQERRKQQL 476



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)

Query: 228  DQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEK-----QQQ 282
            +QL  EE    +L  + +Q+ +E E      Q    E E   R +   +  K     Q++
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090

Query: 283  DQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQ-----EVQKR 337
            +Q+ R   E R + E E +  R E ++    + L+R + E RR +EL  Q     EVQ+ 
Sbjct: 1091 EQLLREEPEKRRRQERERQC-REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149

Query: 338  KQLELRQE-EERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
            ++  LR+E E+RRR+E E + ++EE +++++E       + R QE
Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 46/171 (26%), Positives = 92/171 (53%), Gaps = 24/171 (14%)

Query: 229 QLDDEEGLPEKLVIKNQQF---HKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQV 285
           QL  E+ L  +  ++ +Q    H+++ +  R  Q    E E    W        +++++ 
Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL-------KREEET 464

Query: 286 DRNIKEAR-EKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQ 344
           +R+ +E R ++L+ + E  R E  + L  ++  RR+++ RR ++L  ++ ++R+Q   RQ
Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEE--RREQQERREQQLRREQEERREQRLKRQ 522

Query: 345 EEERR-----RREEEMRRQQEE----MMRRQQEGFKGTFPDAREQEIRMGQ 386
           EEE R     R E+++RR+QEE    +++R++E  K    + REQ ++  Q
Sbjct: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEE--KRLEQERREQRLKREQ 571



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 43/149 (28%), Positives = 78/149 (52%), Gaps = 11/149 (7%)

Query: 243 KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEA 302
           + QQ  +E+E+  R  Q    + E     +   E + +++ Q+ R  +  RE+     + 
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406

Query: 303 ARHEHQV----MLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERR---RREEEM 355
            R E Q+     L R+  +RR++E  R E+ H QE  +R+Q   R++EERR   +REEE 
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQE--RREQRLKREQEERRDWLKREEET 464

Query: 356 RRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
            R ++E  RR+Q+  +    + RE+ +++
Sbjct: 465 ERHEQE--RRKQQLKRDQEEERRERWLKL 491



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 44/155 (28%), Positives = 80/155 (51%), Gaps = 15/155 (9%)

Query: 238  EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
            EK   + ++  +E EQ  R  +      E+  +++   E++ Q+++Q+ R  +E R   E
Sbjct: 987  EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQ-QEEEQLLREEREKRRLQE 1045

Query: 298  MEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEE---------R 348
             E +  R E ++    + L+  + E RR +EL   E Q RK+ EL+QEEE         R
Sbjct: 1046 RERQY-REEEELQQEEEQLLGEERETRRRQEL---ERQYRKEEELQQEEEQLLREEPEKR 1101

Query: 349  RRREEEMR-RQQEEMMRRQQEGFKGTFPDAREQEI 382
            RR+E E + R++EE+ + +++  +      R QE+
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 42/130 (32%), Positives = 64/130 (49%), Gaps = 8/130 (6%)

Query: 243  KNQQFHKEREQPPRFAQPGS--FEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM 300
            + +Q  +ERE+    +Q     F  E  +R +   +  + QQ       +E + +LE + 
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834

Query: 301  EAARHEHQVMLMRQDLMRRQEELRRME-ELHNQEVQKRKQLELRQEEERRRREEEMRRQQ 359
            +  R E       ++    QE+ RR E EL  +E QKR     RQE ER+ REE +RRQQ
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKR-----RQERERKLREEHIRRQQ 1889

Query: 360  EEMMRRQQEG 369
            +E  R +Q G
Sbjct: 1890 KEEQRHRQVG 1899



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 44/170 (25%), Positives = 86/170 (50%), Gaps = 19/170 (11%)

Query: 232 DEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYE-YAMRWKALIEMEKQQQDQVDRNIK 290
           +EE   E+   + QQ  +E+E+          E E    R ++  ++ ++Q+++ ++ +K
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551

Query: 291 EAREKL------EMEMEAARHEHQVMLMRQDLMRRQEELRRMEE------LHNQEVQKRK 338
              EK       E  ++  + E +  L++++  RRQ+ L+R +E      L  +EV++ +
Sbjct: 552 REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLE 611

Query: 339 QLELRQEEERRRREEEMRRQQ-----EEMMRRQQEGFKGTFPDAREQEIR 383
           Q E R++  +R   EE RRQQ     E+  RRQQ+  +    + REQ ++
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ-LRREQQERREQRLK 660



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 38/147 (25%), Positives = 76/147 (51%), Gaps = 10/147 (6%)

Query: 239  KLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEM 298
            K + + QQ H+++ Q  +F Q      E  +R +   +  +Q +D+  R  ++ R++ E 
Sbjct: 1516 KFLEEEQQLHRQQRQR-KFLQE-----EQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569

Query: 299  EMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEE--MR 356
            +  + +   +   + +  +RRQE+ R+  E   Q  ++  Q +LRQE +R+ RE+E  ++
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629

Query: 357  RQQEEMMRRQQEG--FKGTFPDAREQE 381
             ++E+ + RQ+    F    P  R QE
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQE 1656



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 32/108 (29%), Positives = 65/108 (60%), Gaps = 5/108 (4%)

Query: 277 MEKQQQDQVDRNIK-EAREKLEMEM---EAARHEHQVMLMRQDLMRRQEELRRMEELHNQ 332
           ++++Q++++++ +K E  E+LE E    +  + E      RQ L++ +E+  R ++   +
Sbjct: 590 LKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRR 649

Query: 333 EVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQ 380
           E Q+R++  L++EEE  R E+ ++R+ EE  RR+QE  +     ARE+
Sbjct: 650 EQQERREQRLKREEEEERLEQRLKREHEE-ERREQELAEEEQEQARER 696



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 46/141 (32%), Positives = 68/141 (48%), Gaps = 16/141 (11%)

Query: 242 IKNQQFHKEREQPPRFAQ-PGSFEYEYAMRWKALIEMEKQQQD-----QVDRNIKEAREK 295
           +K ++  +  EQ  R  Q     E E   RW  L E E+++Q      Q+ R  +E RE+
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517

Query: 296 LEMEMEAARHEHQVMLMRQDLMRRQEELR----RMEELHNQEVQKRKQLELRQEEERR-- 349
                E      Q +   Q L R QEE R    + EE    E ++R+Q   R++EERR  
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577

Query: 350 --RREEEMRRQQEEMMRRQQE 368
             +REEE  R+Q+ + R Q+E
Sbjct: 578 LLKREEE--RRQQRLKREQEE 596



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 45/162 (27%), Positives = 80/162 (49%), Gaps = 25/162 (15%)

Query: 243 KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEA 302
           K  QF +E EQ  R  +    + E       L E +++++ Q  R  ++ R +LE E + 
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEE----DGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884

Query: 303 ARH--------EHQVMLMRQDLMRRQEELRRMEE----LHNQEVQKRKQLELRQEEE--- 347
            RH        + Q+   +Q L   +EEL+R E        QE Q R++ +L+QEEE   
Sbjct: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944

Query: 348 ------RRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIR 383
                 RRR+E E + ++++ +++++E   G  P+ R ++ R
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 48/173 (27%), Positives = 89/173 (51%), Gaps = 18/173 (10%)

Query: 228  DQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRW---KALIEMEK--QQQ 282
            +QL  EE    +   + +Q+ K+++   +  Q    E E   R    K   E E+  Q++
Sbjct: 941  EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000

Query: 283  DQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLEL 342
            +Q+ R  +E R + E E +  R + ++    + L+R + E RR++E   +E Q R++ EL
Sbjct: 1001 EQLLREEREKRRRQEWERQY-RKKDELQQEEEQLLREEREKRRLQE---RERQYREEEEL 1056

Query: 343  RQEEE---------RRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
            +QEEE         RRR+E E + ++EE +++++E      P+ R ++ R  Q
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQ 1109



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 34/148 (22%), Positives = 81/148 (54%), Gaps = 5/148 (3%)

Query: 243 KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEA 302
           + ++  +E+ Q  +  +   F  E  +R + L+E+ ++ +++  +  +E ++++  E E 
Sbjct: 184 EERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEE 243

Query: 303 AR-HEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMR---RQ 358
               + + +L +++   ++EE +R  EL  +E Q RK LE ++    R+ EE+ +   R+
Sbjct: 244 KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK-LERQELRRERQEEEQQQQRLRR 302

Query: 359 QEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
           ++++ R+Q+E  +    + REQ+ R  Q
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQ 330



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 41/167 (24%), Positives = 87/167 (52%), Gaps = 12/167 (7%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIE-MEKQQQDQVDRNI 289
           ++EE L ++L  + Q     REQ  R  Q    E E  +  +   + ++++Q+++ D+ +
Sbjct: 523 EEEERLQQRLRSEQQL---RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579

Query: 290 KEAREKLEMEMEAARHEH-QVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLEL---RQE 345
           K   E+ +  ++  + E  +  L R+++ R ++E RR + L  +E ++ ++ +L    ++
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639

Query: 346 EERR----RREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQMA 388
           EERR    RRE++ RR+Q      ++E  +       E+E R  ++A
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 46/158 (29%), Positives = 77/158 (48%), Gaps = 17/158 (10%)

Query: 225 EPMDQLDDEEGLPEKLVI------KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEME 278
           E +++L+ EE   ++L        + QQ  K  EQ  R  Q    E +     +   E E
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664

Query: 279 KQQQDQ-VDRNIKEAREKLEM---EMEAARHEHQVMLMRQDLMRRQEELRRMEELHN--- 331
           +++ +Q + R  +E R + E+   E E AR   +  + +       E   R  ++++   
Sbjct: 665 EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724

Query: 332 -QEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQE 368
            QE Q+R+Q    QEE+RRRRE E++ Q+EE   RQQ+
Sbjct: 725 KQEGQRRRQ---EQEEKRRRRESELQWQEEERAHRQQQ 759



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 28/107 (26%), Positives = 63/107 (58%), Gaps = 15/107 (14%)

Query: 276  EMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQ--- 332
            ++ +++++++ R  +E R + E E +  R E Q+    + L+R + E RR +E   Q   
Sbjct: 904  QLLQEEEEELQREEREKRRRQEQERQY-REEEQLQQEEEQLLREEREKRRRQERERQYRK 962

Query: 333  --EVQKRKQLELRQEEERRRR---------EEEMRRQQEEMMRRQQE 368
              ++Q++++  L +E E+RRR         EEE+++++E+++R ++E
Sbjct: 963  DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 39/151 (25%), Positives = 79/151 (52%), Gaps = 10/151 (6%)

Query: 238  EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
            E+   K  +  +E EQ  R  +      E   +++   E++ Q+++Q+    +E R + E
Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ-QEEEQLLGEERETRRRQE 1075

Query: 298  MEM------EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRR 351
            +E       E  + E Q++    +  RRQE  R+  E   +E+Q+ ++  LR+E E+RRR
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE--EEELQQEEEQLLREEREKRRR 1133

Query: 352  EE-EMRRQQEEMMRRQQEGFKGTFPDAREQE 381
            +E E + ++EE +++++E      P+ R ++
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 37/153 (24%), Positives = 77/153 (50%), Gaps = 7/153 (4%)

Query: 229  QLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRN 288
            Q  +EE L ++   + Q   +ERE+  R  +    E +Y    K   + E+   ++ ++ 
Sbjct: 929  QYREEEQLQQE---EEQLLREEREKRRRQER----ERQYRKDKKLQQKEEQLLGEEPEKR 981

Query: 289  IKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEER 348
             ++ REK   E E  + E + +L  +   RR++E  R     ++  Q+ +QL   + E+R
Sbjct: 982  RRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR 1041

Query: 349  RRREEEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
            R +E E + ++EE +++++E   G   + R ++
Sbjct: 1042 RLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 4/98 (4%)

Query: 276  EMEKQQQDQVDRNIKEAREKLEME--MEAARHEHQVMLMRQDLMRRQEELRRMEELHNQE 333
            E E+++  Q DR+  E  E+LE E   EA R + +    +Q L   +EE RR +E  +++
Sbjct: 1280 EQERRRWQQRDRHFPE-EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET-DRK 1337

Query: 334  VQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFK 371
             ++ +QL   +EE+  RR+E  R+ +EE +R Q++G K
Sbjct: 1338 FREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 39/164 (23%), Positives = 81/164 (49%), Gaps = 12/164 (7%)

Query: 228 DQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDR 287
           ++ +  E    K  +K  Q  + RE+  +  +    E +     +   E E++++ ++ R
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521

Query: 288 NIKEAR--EKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQE 345
             +E R  ++L  E +  R + +    R++ + ++EE +R+E+   ++  KR+Q E R +
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEE----RREQLLKREEEKRLEQERREQRLKREQEERRDQ 577

Query: 346 ---EERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
               E  RR++ ++R+QEE   R ++  K    +  EQE R  Q
Sbjct: 578 LLKREEERRQQRLKREQEE---RLEQRLKREEVERLEQEERREQ 618



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 39/137 (28%), Positives = 69/137 (50%), Gaps = 12/137 (8%)

Query: 243  KNQQFHKEREQPPRFAQPGSFEYEYAM-----RWKALIEMEKQQQDQVDRNIKEAREKLE 297
            ++++F +E +Q  R  +   F  E        R +  +E E+Q + +  R  +E  + L+
Sbjct: 1412 RDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQ 1471

Query: 298  MEMEAARHEHQ---VMLMRQDLMRRQEELR--RMEELHNQEVQKRKQLELRQEEERRRRE 352
               E   H  +     L  +  +RRQE  R  R +EL +QE + RK LE  Q+  R++R+
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE-RKFLEEEQQLHRQQRQ 1530

Query: 353  EEMRRQQEEMMRRQQEG 369
             +   Q+E+ +RRQ+ G
Sbjct: 1531 RKFL-QEEQQLRRQERG 1546



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 41/139 (29%), Positives = 71/139 (51%), Gaps = 14/139 (10%)

Query: 232  DEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKE 291
            D + L E+  ++ Q    EREQ  R  +   F  E  +    L E E+QQ  + +R+   
Sbjct: 1642 DRKFLEEEPQLRRQ----EREQQLRHDRDRKFREEEQL----LQEGEEQQLRRQERD--- 1690

Query: 292  AREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRR- 350
             R+  E E +  R E +   ++++   R++EL R      Q  Q+ +Q +LR++E  R+ 
Sbjct: 1691 -RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI 1749

Query: 351  -REEEMRRQQEEMMRRQQE 368
              EE++R ++EE   R+QE
Sbjct: 1750 LEEEQLRPEREEQQLRRQE 1768



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 39/136 (28%), Positives = 69/136 (50%), Gaps = 11/136 (8%)

Query: 239  KLVIKNQQFH-KEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
            K + + QQ   +EREQ  R  +   F  E     +   + + ++++Q  R  +  R+ LE
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE 1450

Query: 298  MEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLE-----LRQEEERRRRE 352
             E +  +  H+     + L++ +EE    ++LH QE + RK LE      RQE +R+ RE
Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREE----QQLHRQE-RDRKFLEEEQQLRRQERDRKFRE 1505

Query: 353  EEMRRQQEEMMRRQQE 368
            +E+R Q+ E    ++E
Sbjct: 1506 QELRSQEPERKFLEEE 1521



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 41/152 (26%), Positives = 80/152 (52%), Gaps = 9/152 (5%)

Query: 243  KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEA 302
            ++++F +E +Q  R  +   F  E     +  +E + ++++Q+ +  ++ + + +     
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748

Query: 303  ARHEHQVMLMRQDL-MRRQEELRRMEELHNQEVQKRKQLELR-QEEERRRREEEMRRQQ- 359
               E Q+   R++  +RRQE  R+  E   Q  Q+R++ +LR QE +R+ REEE  RQ+ 
Sbjct: 1749 ILEEEQLRPEREEQQLRRQERDRKFRE-EEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807

Query: 360  -EEMMRRQQEGFKGTFPDAR----EQEIRMGQ 386
             E+ +R QQ   K  + + +    EQE R+ Q
Sbjct: 1808 EEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ 1839



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 50/166 (30%), Positives = 79/166 (47%), Gaps = 24/166 (14%)

Query: 229  QLDDEEGLPEKLVIKNQQFHKEREQPPR--------FAQPGSFEYEYAMRWKALIEMEKQ 280
            QL D +   +   +  +Q  ++REQ  R        F +    E E     K   + + Q
Sbjct: 1257 QLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR-DRKSQ 1315

Query: 281  QQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDL-MRRQEELR--RMEELHNQEVQKR 337
            ++ Q+ R  +E + + +      R E Q++  R++  +RRQE  R  R EEL +QE Q R
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQE-QGR 1374

Query: 338  KQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIR 383
            K LE  +E+  RR+E E +  +EE   R QE         REQ++R
Sbjct: 1375 KFLE--EEQRLRRQERERKFLKEEQQLRCQE---------REQQLR 1409



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 40/184 (21%), Positives = 88/184 (47%), Gaps = 19/184 (10%)

Query: 202  RKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPG 261
            R+  DR      L +  P    +E   QL  ++   + L  + Q   +ER Q  R  +  
Sbjct: 1496 RQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555

Query: 262  SFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQE 321
             F  E  +R       +++++ Q+ R  ++ + +LE +    + + +  +  +  +RRQE
Sbjct: 1556 KFREEEQLR-------QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608

Query: 322  ELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRR--QQEEMMRRQQEGFKGTFPDARE 379
              +++ +  +++ ++ +QL   +EE++  R+E  R+  ++E  +RRQ+          RE
Sbjct: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE----------RE 1658

Query: 380  QEIR 383
            Q++R
Sbjct: 1659 QQLR 1662



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 34/149 (22%), Positives = 77/149 (51%), Gaps = 11/149 (7%)

Query: 243  KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKL-EMEME 301
            + +Q  +E ++  +     S E +  +R +     EK+++ + DR  +E  + L E E +
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREE---REEKRRRQETDRKFREEEQLLQEREEQ 1351

Query: 302  AARHEHQVMLMRQDLMRRQEELRR-MEELHNQEVQKRKQLELRQEEERR--RREEEMRRQ 358
              R + +    R++ +R QE+ R+ +EE      Q+R++  L++E++ R   RE+++R+ 
Sbjct: 1352 PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQD 1411

Query: 359  QEEMMRRQQEGFKGTFPDAR----EQEIR 383
            ++   R +++       D +    EQ++R
Sbjct: 1412 RDRKFREEEQQLSRQERDRKFREEEQQVR 1440



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 38/151 (25%), Positives = 77/151 (50%), Gaps = 12/151 (7%)

Query: 243  KNQQFHKEREQPPRFAQPGSF-EYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEME 301
            ++++F  E ++  R  Q   F E E  +R +   E ++Q + + DR  +E  + L+   E
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ---EGQQQLRQERDRKFREDEQLLQEREE 1633

Query: 302  AARHEHQ---VMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMR-- 356
               H  +     L  +  +RRQE  +++    +++ ++ +QL    EE++ RR+E  R  
Sbjct: 1634 QQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKF 1693

Query: 357  RQQEEMMRRQQEGFKGTFPDAREQEIRMGQM 387
            R++E+ +RRQ+   K       EQ++R  ++
Sbjct: 1694 REEEQQLRRQERERKFL---QEEQQLRRQEL 1721



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 42/160 (26%), Positives = 78/160 (48%), Gaps = 22/160 (13%)

Query: 243  KNQQFHKEREQPPRFAQPGSF-EYEYAMRWKA----------LIEMEKQQQDQVDRNIKE 291
            ++++F +E +Q  R  +   F E E  +R +           L E E+QQ  + +R+   
Sbjct: 1428 RDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD--- 1484

Query: 292  AREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE---LHNQEVQKR----KQLELRQ 344
             R+ LE E +  R E       Q+L  ++ E + +EE   LH Q+ Q++    +Q   RQ
Sbjct: 1485 -RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1543

Query: 345  EEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
            E  ++RR++  R+ +EE   RQ+   +      R+++ R+
Sbjct: 1544 ERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL 1583



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 36/148 (24%), Positives = 79/148 (53%), Gaps = 18/148 (12%)

Query: 236  LPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREK 295
            L E+L  + Q   +E E+  R  +      E   +++   +++ Q+++Q+ R  +E R +
Sbjct: 895  LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ-QEEEQLLREEREKRRR 953

Query: 296  LEMEMEAARH------EHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQE-EER 348
             E E +  +       E Q++    +  RRQE  ++  E   +E+Q+ ++  LR+E E+R
Sbjct: 954  QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE--EEELQQEEEQLLREEREKR 1011

Query: 349  RRRE--------EEMRRQQEEMMRRQQE 368
            RR+E        +E+++++E+++R ++E
Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREERE 1039



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/164 (29%), Positives = 84/164 (51%), Gaps = 32/164 (19%)

Query: 231  DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
            +DE+ L E+   + QQ H++ E+  +F      E E  +R +   E E+Q +   DR  +
Sbjct: 1623 EDEQLLQER---EEQQLHRQ-ERDRKF-----LEEEPQLRRQ---EREQQLRHDRDRKFR 1670

Query: 291  EAREKL-EMEMEAARHEHQVMLMRQD--LMRRQEELRRM----EELHNQEVQK--RKQLE 341
            E  + L E E +  R + +    R++   +RRQE  R+     ++L  QE+++  R++ +
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730

Query: 342  LRQE--EERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIR 383
            LRQE  +E+ RR+E  R+  EE   R         P+  EQ++R
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLR---------PEREEQQLR 1765



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 30/133 (22%), Positives = 63/133 (47%), Gaps = 5/133 (3%)

Query: 236  LPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREK 295
            L E+  ++ ++  K RE+     +    +     R +  +E E+Q + Q     +  R+ 
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ-----ERDRKF 1503

Query: 296  LEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM 355
             E E+ +   E + +   Q L R+Q + + ++E      Q+R Q   +  + + R EE++
Sbjct: 1504 REQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQL 1563

Query: 356  RRQQEEMMRRQQE 368
            R+++EE    +QE
Sbjct: 1564 RQEREEQQLSRQE 1576



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 33/117 (28%), Positives = 64/117 (54%), Gaps = 7/117 (5%)

Query: 274  LIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQE 333
            L E E+QQ  + +R+    R+ LE E +  R E +  L      + +EE + ++E   Q+
Sbjct: 1628 LQEREEQQLHRQERD----RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683

Query: 334  VQKRKQ-LELRQEEERRRREEEMRR--QQEEMMRRQQEGFKGTFPDAREQEIRMGQM 387
            ++++++  + R+EE++ RR+E  R+  Q+E+ +RRQ+   K    +   QE    Q+
Sbjct: 1684 LRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 35/153 (22%), Positives = 74/153 (48%), Gaps = 7/153 (4%)

Query: 236  LPEKLVIKNQQFHKE-REQPPRFAQPGSFEYEYAMRWKALIEMEK----QQQDQVDRNIK 290
            L E+  ++ Q+  ++ RE+     +    +     R++ ++E E+    +++ Q+ R  +
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769

Query: 291  EAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRR 350
            + + + E ++   R E Q+     D   R+EE  R E    Q   +++  + R EEE+ +
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQ 1829

Query: 351  REEEMRRQQEEMMR--RQQEGFKGTFPDAREQE 381
             EE+ +R ++E  R  R +E F       RE++
Sbjct: 1830 LEEQEQRLRQERDRQYRAEEQFATQEKSRREEQ 1862



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 19/153 (12%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           E L+   +Q   +R   PR  Q    E E   R        +Q++ + +R + E  E+ E
Sbjct: 107 ESLLQDRRQEEDQRRFEPRDRQ---LEEEPGQR-------RRQKRQEQERELAEGEEQSE 156

Query: 298 ME-----MEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRRE 352
            +      +  R + ++   RQ+   R+E  RR EE   Q  +  +  E   EE+ RRRE
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREE--RRAEEEQLQSCKGHETEEFPDEEQLRRRE 214

Query: 353 --EEMRRQQEEMMRRQQEGFKGTFPDAREQEIR 383
             E  R+ +EE  ++++E     F +  E+E R
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWR 247



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 31/128 (24%), Positives = 62/128 (48%), Gaps = 11/128 (8%)

Query: 243  KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEARE--KLEMEM 300
            + +Q  +ERE+ P   Q    ++          E E + Q+Q  + ++E +   + E E 
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFR---------EEELRHQEQGRKFLEEEQRLRRQERER 1390

Query: 301  EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE 360
            +  + E Q+    ++   RQ+  R+  E   Q  ++ +  + R+EE++ RR+E  R+  E
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE 1450

Query: 361  EMMRRQQE 368
            E  + +QE
Sbjct: 1451 EEQQLRQE 1458



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 5/146 (3%)

Query: 241  VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM 300
            +++ +Q   ERE+     Q    ++    + +   E ++ +  + DR  +E     E ++
Sbjct: 1749 ILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-----EEQL 1803

Query: 301  EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE 360
               R E Q+   ++D   R EE +   E   Q +++ +  + R EE+   +E+  R +QE
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863

Query: 361  EMMRRQQEGFKGTFPDAREQEIRMGQ 386
                 +Q+  +      RE+ IR  Q
Sbjct: 1864 LWQEEEQKRRQERERKLREEHIRRQQ 1889



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 35/158 (22%), Positives = 79/158 (50%), Gaps = 15/158 (9%)

Query: 218  FPRPVTVEPMDQLD----DEEGLPEKLVIKNQQFHKEREQPP--RFAQPGSFEYEYAMRW 271
            FP    +E  +Q +    D +   EK +++ ++  K R Q    +F +      E   + 
Sbjct: 1293 FPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352

Query: 272  KALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHN 331
                E +++ +++  R+ ++ R+ LE E    R E +     +  ++ +++LR  E    
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE-----RKFLKEEQQLRCQER--E 1405

Query: 332  QEVQKRKQLELRQEEERRRREEEMR--RQQEEMMRRQQ 367
            Q++++ +  + R+EE++  R+E  R  R++E+ +RRQ+
Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE 1443



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 37/134 (27%), Positives = 64/134 (47%), Gaps = 14/134 (10%)

Query: 249 KEREQPPRFAQPGSFEYEYAMRWKALIEMEKQ---QQDQVDRN-----IKEAREKLEMEM 300
           +ER+Q  +   P   E E   R +   E E Q   +++Q+ R      ++E  + L+ + 
Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860

Query: 301 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQ---EVQKRKQLELRQEEE---RRRREEE 354
           E  R + Q    +      +E  RR   L+ +   + Q RK+ +L QEEE   +R   E+
Sbjct: 861 ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREK 920

Query: 355 MRRQQEEMMRRQQE 368
            RRQ++E   R++E
Sbjct: 921 RRRQEQERQYREEE 934



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 31/121 (25%), Positives = 62/121 (51%), Gaps = 3/121 (2%)

Query: 249 KEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRN-IKEAREKLEMEMEAARHEH 307
           +E E+  R  Q      ++  +W+A  + E+ +Q    R  ++E RE+ ++  E  +   
Sbjct: 749 QEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER-QLRAEERQQRE 807

Query: 308 QVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQ 367
           Q  L  ++   ++   RR  E   Q +++ +QL+ R+E  ++ +EEE   Q+++  RR Q
Sbjct: 808 QRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ-RRERAQQLQEEEDGLQEDQERRRSQ 866

Query: 368 E 368
           E
Sbjct: 867 E 867



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 38/167 (22%), Positives = 81/167 (48%), Gaps = 23/167 (13%)

Query: 225 EPMD-QLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQD 283
           EP D QL++E G         Q+  ++R++  R    G    E + + + L + ++Q++D
Sbjct: 123 EPRDRQLEEEPG---------QRRRQKRQEQERELAEGE---EQSEKQERLEQRDRQRRD 170

Query: 284 QV------DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQE--ELRRMEELHNQEVQ 335
           +       +   +E R   E ++++ +         ++ +RR+E  ELRR      Q+ +
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230

Query: 336 KRKQLELRQEEERR--RREEEMRRQQEEMMRRQQEGFKGTFPDAREQ 380
           + +Q  + QEEE +  R+ E + R++EE ++ ++   +    +  EQ
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 15/133 (11%)

Query: 266 EYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRR 325
           E  ++W+      +QQQ++  R     + + E + E  R   Q +  R  L  ++E   R
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR---QRLSARPPLREQRERQLR 799

Query: 326 MEELHNQEVQKRKQLELRQEEERRRREEE------------MRRQQEEMMRRQQEGFKGT 373
            EE   +E +   + E +++  R+RRE E             RR++ + ++ +++G +  
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED 859

Query: 374 FPDAREQEIRMGQ 386
               R QE R  Q
Sbjct: 860 QERRRSQEQRRDQ 872



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 32/147 (21%), Positives = 69/147 (46%), Gaps = 17/147 (11%)

Query: 224  VEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQD 283
            +E   QL  +EG         QQ  +ER++  R       E E  ++ +   ++ +Q++D
Sbjct: 1598 MEDEQQLRRQEG--------QQQLRQERDRKFR-------EDEQLLQEREEQQLHRQERD 1642

Query: 284  QVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELR 343
            +     +    + E E +      +     + L++  EE +   +  +++ ++ +Q   R
Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702

Query: 344  QEEERR--RREEEMRRQQEEMMRRQQE 368
            QE ER+  + E+++RRQ+ E   R++E
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEE 1729



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 29/145 (20%), Positives = 72/145 (49%), Gaps = 14/145 (9%)

Query: 229  QLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRN 288
            Q  +EE L  +   K +Q +++ +Q          E E A+R   +    K ++++  R 
Sbjct: 1198 QYREEEELQRQ---KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYC--KGRENEQFRQ 1252

Query: 289  IKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEEL-----HNQEVQKRKQLELR 343
            +++++ +     +  +H    +L  Q    R++E RR ++        +++++ +Q E +
Sbjct: 1253 LEDSQLRDRQSQQDLQH----LLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAK 1308

Query: 344  QEEERRRREEEMRRQQEEMMRRQQE 368
            + + + + E+++ R++ E  RR+QE
Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQE 1333



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 37/161 (22%), Positives = 70/161 (43%), Gaps = 24/161 (14%)

Query: 232 DEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKE 291
           +EE   ++L  + Q+  +ER +          E E   R   +    ++Q+ Q  R  +E
Sbjct: 677 EEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQE 736

Query: 292 A-REKLEMEM-----EAARHEHQVMLMRQDLM----------RRQEEL--------RRME 327
             R + E E+     E A  + Q    R+D            R ++ L        +R  
Sbjct: 737 EKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER 796

Query: 328 ELHNQEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQE 368
           +L  +E Q+R+Q  L +EEE+ +R  + R +++E+   ++E
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE 837



 Score = 32.7 bits (73), Expect = 0.73
 Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 33/122 (27%)

Query: 276  EMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLM------------------ 317
            E EK++Q++     ++ RE+ E++ +  +  ++    R DL                   
Sbjct: 1187 EQEKRRQERE----RQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYC 1242

Query: 318  --RRQEELRRMEELHNQEVQKRKQLE-LRQEEERRRREEEMRRQQ--------EEMMRRQ 366
              R  E+ R++E+   ++ Q ++ L+ L  E++ R RE+E RR Q        EE + R+
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE 1302

Query: 367  QE 368
            ++
Sbjct: 1303 EQ 1304


>gi|123173757 RAVER1 [Homo sapiens]
          Length = 756

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 38  PPPIPANGQQASS---------QNEGLTIDLKNFRKPGEKT---FTQRSRLFVGNLPPDI 85
           PP  P +G +  +         + E   +D +  RK  E T   F  R ++ +  LP D+
Sbjct: 28  PPLSPKSGAEVEAGDAAERRAPEEELPPLDPEEIRKRLEHTERQFRNRRKILIRGLPGDV 87

Query: 86  TEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFAC 145
           T +E+  L   Y +    F+ K KG  F+ L     AE A        LR ++L V+   
Sbjct: 88  TNQEVHDLLSDY-ELKYCFVDKYKGTAFVTLLNGEQAEAAINAFHQSRLRERELSVQLQP 146

Query: 146 HSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDR-GRPSGKGIVEFSGKPAARKA 204
             A L V NLP  ++ +  EE    FG +ER  ++  +R G+  G G  E+  K +A +A
Sbjct: 147 TDALLCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARA 206



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 46/198 (23%), Positives = 75/198 (37%), Gaps = 20/198 (10%)

Query: 44  NGQQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEV 103
           NG+QA +            R+   +     + L V NLPP +T+++  +L   +G     
Sbjct: 119 NGEQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERC 178

Query: 104 FI------HKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFA---------CHSA 148
           F+       + KG+GF     +  A  AK +L   PL  + L V +           HS 
Sbjct: 179 FLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSR 238

Query: 149 SLTVRNLPQYVSN-ELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDR 207
            L V  LP   ++ + L  A S         +     G+  G  ++E+     A +A  +
Sbjct: 239 CLCVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQ 298

Query: 208 CS----EGSFLLTTFPRP 221
                  GS L  +F  P
Sbjct: 299 ADGLSLGGSHLRVSFCAP 316


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 50/165 (30%), Positives = 82/165 (49%), Gaps = 20/165 (12%)

Query: 239 KLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQV-----------DR 287
           KL++  QQ   E +   +  Q  S + +  +    L     QQQ++            + 
Sbjct: 243 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREE 302

Query: 288 NIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEEL--------RRMEELHNQEVQKRKQ 339
            I+E  EK+  + E  R + ++M  +++ MRRQEE+        R +EE  +++ + R+Q
Sbjct: 303 KIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 362

Query: 340 LELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
            E RQEEE+ R E+E R++QE  M RQ+E  +      REQE  M
Sbjct: 363 EEKRQEEEKIR-EQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM 406



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 40/170 (23%), Positives = 92/170 (54%), Gaps = 8/170 (4%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRW--KALIEMEK--- 279
           E + + +++    E+ + + ++   E+E+  R  +   +E E  +R   + + E EK   
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361

Query: 280 -QQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQK-- 336
            +++ Q +  I+E  ++ E E +  R E ++    + +  ++E ++  EE   ++ +K  
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421

Query: 337 RKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
            ++ E++++EE+ RR+EE  R+QE+ +R Q+E  +      +EQE +MG+
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGE 471



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 44/159 (27%), Positives = 82/159 (51%), Gaps = 10/159 (6%)

Query: 233 EEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEA 292
           EE + E+  I+ Q+  ++ E+  R  +    +     R +  I  ++++  + +  ++E 
Sbjct: 350 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQ 409

Query: 293 REKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE--LHNQEVQKRKQLELRQEEERRR 350
            EK+  + E    + + M  +++ MRRQEE  R +E  +  QE + R+Q E+ QE+E + 
Sbjct: 410 EEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469

Query: 351 REEEMR--------RQQEEMMRRQQEGFKGTFPDAREQE 381
            E+E +        ++QEE MRRQ+E  +      REQE
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE 508



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 39/166 (23%), Positives = 88/166 (53%), Gaps = 11/166 (6%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKA--LIEMEKQQQ 282
           E M + +++ G  E+ + + ++  +E+E+  R  +    E E  +R +   + E E+  Q
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 463

Query: 283 DQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEEL--HNQEVQKRKQL 340
           +Q ++  ++  +  E E +    E ++    + +  +++++R  EE     +E+ + ++ 
Sbjct: 464 EQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 523

Query: 341 ELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
           ++ ++EE+   +EE  ++QEE MRRQ+E         REQE+R+ Q
Sbjct: 524 KMWEQEEKMCEQEEKMQEQEEKMRRQEE-------KMREQEVRLRQ 562



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 38/148 (25%), Positives = 79/148 (53%), Gaps = 1/148 (0%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           E+ + + ++  +ERE+  +  +    E E  MR +  +  EK+++ +    +   +E+  
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346

Query: 298 MEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERR-RREEEMR 356
            E+E   HE + +  +++  + +E++R  E+   QE +  +Q E  +E+E + R +EEM 
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM 406

Query: 357 RQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           ++QEE M  Q+E       + +EQE +M
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEKM 434



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 40/152 (26%), Positives = 83/152 (54%), Gaps = 6/152 (3%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQD--QVDRNIKEAREK 295
           E+ + + ++  +E+E+  +  +    E E  M W+   EM++Q++   + +  I+E  +K
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKM-WEQEEEMQEQEEKMRRQEEKIREQEKK 447

Query: 296 LEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQ---KRKQLELRQEEERRRRE 352
           +  + E  R + ++M  +++ M  QE     +E   QE +   +R++ ++R++E++ R +
Sbjct: 448 IREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507

Query: 353 EEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           EE  R+QEEMM+ Q+E          EQE +M
Sbjct: 508 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 539



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 35/146 (23%), Positives = 82/146 (56%), Gaps = 7/146 (4%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKA--LIEMEKQQQ 282
           E M + +++    E+ + + ++  +E+E+  R  +    E E  M  +   + E E + Q
Sbjct: 425 EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQ 484

Query: 283 DQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLEL 342
           +Q ++ ++   EK+  + +  R + + +  ++++M+ QEE  +M E   +E    ++ ++
Sbjct: 485 EQEEK-MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE--KMWE--QEEKMCEQEEKM 539

Query: 343 RQEEERRRREEEMRRQQEEMMRRQQE 368
           +++EE+ RR+EE  R+QE  +R+Q+E
Sbjct: 540 QEQEEKMRRQEEKMREQEVRLRQQEE 565



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 34/141 (24%), Positives = 76/141 (53%), Gaps = 5/141 (3%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAM-RWKALIEMEKQQQD 283
           E M + +++    EK + + ++  +E+E+  +  +    E E  M   +A ++ ++++  
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR 491

Query: 284 QVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELR 343
           + +  I+E  +K+  + E  R + ++M  +++ M  QEE    +E   QE +++    +R
Sbjct: 492 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK----MR 547

Query: 344 QEEERRRREEEMRRQQEEMMR 364
           ++EE+ R +E   RQQEE M+
Sbjct: 548 RQEEKMREQEVRLRQQEEKMQ 568



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 31/120 (25%), Positives = 61/120 (50%), Gaps = 5/120 (4%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQV---DR 287
           + EE + E+  +  +Q  K  EQ  +  +  +   E   + +   E  ++Q+ ++   + 
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509

Query: 288 NIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEE-LRRMEE-LHNQEVQKRKQLELRQE 345
            I+E  E ++ + E    + + M  +++ M+ QEE +RR EE +  QEV+ R+Q E  QE
Sbjct: 510 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 35/147 (23%), Positives = 62/147 (42%), Gaps = 37/147 (25%)

Query: 275 IEMEKQQQDQVDRNIKEAREKLEMEMEAARHE-HQVMLMRQDLMRRQEELRRM------- 326
           + +E  +    D  +KE   KL+ +++    E  ++ L  ++L R+ E  + +       
Sbjct: 193 LSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 252

Query: 327 -----------------------EELHNQEVQKRKQLELRQEEERRRREEEMR------R 357
                                   EL N+  Q++++   RQEE+ + REE+++      R
Sbjct: 253 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIR 312

Query: 358 QQEEMMRRQQEGFKGTFPDAREQEIRM 384
           +QEE MRRQ+E         R QE  M
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQEEMM 339


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 47/160 (29%), Positives = 84/160 (52%), Gaps = 17/160 (10%)

Query: 243 KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEA 302
           K Q+  K REQ  R  Q     +    + +   E  ++Q++++ R  ++  E+ ++  E 
Sbjct: 459 KRQEEEKIREQEKRQEQEAKM-WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEE 517

Query: 303 ARHEHQVMLMRQDLMRRQEEL-RRMEELHNQEVQKRKQLE---------------LRQEE 346
            R E + M  +++ +R QEE+ R+ E++H QE + RKQ E               +R++E
Sbjct: 518 KRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577

Query: 347 ERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
           E+  R+EE  R+QEE +R Q+E  +      +EQE +MG+
Sbjct: 578 EKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 43/130 (33%), Positives = 75/130 (57%), Gaps = 22/130 (16%)

Query: 276 EMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEEL--------RRME 327
           E E++ Q+Q ++ I+E  EK+  + E  R + ++M  +++ MRRQEE+        RR E
Sbjct: 372 EWEEKIQEQEEK-IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 430

Query: 328 ELHNQEVQKRKQLE--------LRQEEERRR-----REEEMRRQQEEMMRRQQEGFKGTF 374
           E+  ++ +K ++LE        +R++EE+R+     RE+E R++QE  M RQ+E  +   
Sbjct: 431 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 490

Query: 375 PDAREQEIRM 384
              REQE +M
Sbjct: 491 EKIREQEEKM 500



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 44/157 (28%), Positives = 81/157 (51%), Gaps = 13/157 (8%)

Query: 238 EKLVIKNQQFHKE---REQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEARE 294
           EK+  + ++ H++   RE+  R  Q   +  E  +R +  I  +K++  + +  I++  E
Sbjct: 498 EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE 557

Query: 295 KLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE--LHNQEVQKRKQLELRQEEERRRRE 352
           K+  + E    + + +  +++ + RQEE  R +E  +  QE + R+Q E+ QE+E +  E
Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617

Query: 353 --------EEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
                   EE  ++QEE MRRQ+E  +      REQE
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 45/163 (27%), Positives = 83/163 (50%), Gaps = 14/163 (8%)

Query: 239 KLVIKNQQFHKEREQPPRFAQPGSFEYEYAMR----WKALIEMEKQQQDQVDRNIKEARE 294
           KL++  QQ   E +   +  Q  S + +  +     W  L + ++++  + +  I+E  E
Sbjct: 316 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 375

Query: 295 KLEMEMEAARHEHQVMLMRQDLMRRQEEL--------RRMEE-LHNQEVQKRKQLELRQE 345
           K++ + E  R + + +  +++ MRRQEE+        RR EE +  +E + R+Q E+  E
Sbjct: 376 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 435

Query: 346 EERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQMA 388
           +E + RE E +  ++E +R Q+E  +      REQE R  Q A
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEK-RQEEEKIREQEKRQEQEA 477



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 36/115 (31%), Positives = 66/115 (57%), Gaps = 6/115 (5%)

Query: 276 EMEKQQQDQV---DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEE--LRRMEELH 330
           E  ++Q+++V   +  I+E  EK+  + E  R + ++   +++ M  QEE    + E++ 
Sbjct: 571 EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 630

Query: 331 NQEVQKRKQLE-LRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
            QE + R+Q E +R++E++ R +EE  R+QEEMM+ Q+E          EQE +M
Sbjct: 631 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 685



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 40/152 (26%), Positives = 78/152 (51%), Gaps = 3/152 (1%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           EK+  + ++ H + E+     +    + E     +  I  ++++  + +   +E  EK+ 
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616

Query: 298 MEMEAARHEHQVMLMRQDLMRRQEELRRMEE--LHNQEVQKRKQLELRQEEERRRREEEM 355
            + E    + + M  +++ MRRQEE  R +E  +  QE + R+Q E+ QE+E +  E+E 
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 676

Query: 356 RR-QQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
           +  +QEE M+ Q+E  +       EQE+R+ Q
Sbjct: 677 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 708



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 41/155 (26%), Positives = 78/155 (50%), Gaps = 11/155 (7%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAR---- 293
           E+ + + ++   E+E+  R  +    E E     +   + E++ ++Q  R  +EA+    
Sbjct: 423 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 482

Query: 294 -EKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRR- 351
            EK+  + E  R + + M  +++ +  QE++R  E+   QE   R++ ++R++EE  R+ 
Sbjct: 483 EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 542

Query: 352 -----EEEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
                +EE  R+QEE M RQ+E         REQE
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 44/154 (28%), Positives = 82/154 (53%), Gaps = 10/154 (6%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRW--KALIEMEK----QQQDQVDRNIKE 291
           E+ + + ++   E+E+  R  +   +E E  +R   + + E EK    +++ Q +  I+E
Sbjct: 409 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 468

Query: 292 AREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE-LHNQEVQKRKQLELRQEEERRR 350
             ++ E E +  R E ++    + +  ++E++ R EE +H QE  K ++ E RQE+E   
Sbjct: 469 QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQE--KIREEEKRQEQEEMW 526

Query: 351 REEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           R+EE  R+QEE+  RQ+E         R+QE +M
Sbjct: 527 RQEEKIREQEEI-WRQKEKIHEQEEKIRKQEEKM 559



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 38/150 (25%), Positives = 79/150 (52%), Gaps = 3/150 (2%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           EK+  + ++  K+ E+  R  +    + E     +  +  ++++  + +  I+E  EK+ 
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602

Query: 298 MEMEAARHEHQVMLMRQDLMRRQEELRRMEE--LHNQEVQKRKQ-LELRQEEERRRREEE 354
            + E  + + + M  +++ M  QEE  + +E  +  QE + R+Q  ++R++EE+ R +EE
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662

Query: 355 MRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           M ++QEE M  Q+E         +EQE +M
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 692



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 38/154 (24%), Positives = 77/154 (50%), Gaps = 8/154 (5%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
           D EE + E+     +Q  K REQ  +  +    E +   + +   E E++  +Q ++  +
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQ---EEKIREQEEMTQEQEEKMGEQEEKMCE 624

Query: 291 EAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRR 350
           +  +  E E +  R E ++    + +  ++E++R  EE+  ++ +K     + ++EE+  
Sbjct: 625 QEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK-----MWEQEEKMC 679

Query: 351 REEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
            +EE  ++QEE MRRQ+E         R+QE +M
Sbjct: 680 EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 41/169 (24%), Positives = 87/169 (51%), Gaps = 12/169 (7%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E + + +++    E+ + + ++  +E+E+  R  +   +E E  MR +  +  EK+++ +
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 427

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLE-LR 343
               +   +E+   E+E   HE + +  +++  + +E++R  E+   QE +  +Q E +R
Sbjct: 428 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 487

Query: 344 QEEER-RRREEEMRRQQE----------EMMRRQQEGFKGTFPDAREQE 381
           ++EE+ R +EE+M RQ+E          E  R++QE         REQE
Sbjct: 488 EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 536



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 36/149 (24%), Positives = 84/149 (56%), Gaps = 6/149 (4%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAM--RWKALIEMEKQQQ 282
           E + + +++    E+ + + ++  +E+E+  R  +  + E E  M  + + + E E++ Q
Sbjct: 571 EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 630

Query: 283 DQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEEL--RRMEELHNQEVQKRKQL 340
           +Q ++ ++   EK+  + +  R + + +  ++++M+ QEE    + E++  QE + ++Q 
Sbjct: 631 EQEEK-MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 689

Query: 341 ELRQEEERRRREEEMR-RQQEEMMRRQQE 368
           E  + +E +  E+E+R RQQEE M+  QE
Sbjct: 690 EKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 19/129 (14%)

Query: 275 IEMEKQQQDQVDRNIKEAREKLE----------MEMEAARHEHQVMLMRQDLMRRQEELR 324
           +++ + ++ ++  N+KE + KLE          ++ EA     ++  +   L  + EE  
Sbjct: 291 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 350

Query: 325 RMEELHNQEVQKRKQLE---------LRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFP 375
               L+ Q+ +K  + E         ++++EE+ R +EE  R+QEE MRRQ+E       
Sbjct: 351 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 410

Query: 376 DAREQEIRM 384
             R QE  M
Sbjct: 411 KMRRQEEMM 419



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 23/133 (17%)

Query: 275 IEMEKQQQDQVDRNIKEAREKLEMEMEAARHE-HQVMLMRQDLMRRQEELRRM------- 326
           + +E  +    D  +KE   KL+ +++    E  ++ L  ++L R+ E  + +       
Sbjct: 266 LSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 325

Query: 327 -------EELHNQEVQKRKQLE--------LRQEEERRRREEEMRRQQEEMMRRQQEGFK 371
                  +EL +   + + Q+E         +Q+EE+  R+EE  ++ EE ++ Q+E  +
Sbjct: 326 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 385

Query: 372 GTFPDAREQEIRM 384
                 REQE +M
Sbjct: 386 EQEEKIREQEEKM 398



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 27/115 (23%), Positives = 57/115 (49%), Gaps = 9/115 (7%)

Query: 225 EPMDQLDDEE-GLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKA--LIEMEKQQ 281
           E M Q  +E+ G  E+ + + ++  +E+E+  R  +    E E  +R +   + E E+  
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664

Query: 282 QDQVDR------NIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELH 330
           Q+Q ++       + E  EK++ + E  R + + M  ++  +R+QEE  +  + H
Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 719


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 64/224 (28%), Positives = 101/224 (45%), Gaps = 42/224 (18%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           E+L I+ +Q  +++ Q          E E     +  +E E+ ++++++R   E RE+LE
Sbjct: 138 EELEIQRRQLQEQQRQK---------ELERERLERERMERERLERERLERERLE-RERLE 187

Query: 298 ---MEMEAARHEHQVMLMRQDLMRRQEELRRMEEL--HNQEVQKRKQLE-LRQEEERRRR 351
              +E E    E Q  L RQ+ + RQE L R E L    QE Q+R++LE L +E + R R
Sbjct: 188 QEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERER 247

Query: 352 EEEMRRQQEEMMRRQ-----------QEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGA 400
           +E++ R+Q E  R +           +        D+   E  + Q A   A   + +G 
Sbjct: 248 QEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGL-QAASQPAETPSQQGI 306

Query: 401 M-------PPAPVPAG-------TPAPPGPATMMPDGTLGLTPP 430
           +       PP P+P G        P PPGP    P  + G  PP
Sbjct: 307 VLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP 350


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 64/224 (28%), Positives = 101/224 (45%), Gaps = 42/224 (18%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           E+L I+ +Q  +++ Q          E E     +  +E E+ ++++++R   E RE+LE
Sbjct: 138 EELEIQRRQLQEQQRQK---------ELERERLERERMERERLERERLERERLE-RERLE 187

Query: 298 ---MEMEAARHEHQVMLMRQDLMRRQEELRRMEEL--HNQEVQKRKQLE-LRQEEERRRR 351
              +E E    E Q  L RQ+ + RQE L R E L    QE Q+R++LE L +E + R R
Sbjct: 188 QEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERER 247

Query: 352 EEEMRRQQEEMMRRQ-----------QEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGA 400
           +E++ R+Q E  R +           +        D+   E  + Q A   A   + +G 
Sbjct: 248 QEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGL-QAASQPAETPSQQGI 306

Query: 401 M-------PPAPVPAG-------TPAPPGPATMMPDGTLGLTPP 430
           +       PP P+P G        P PPGP    P  + G  PP
Sbjct: 307 VLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP 350


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 40/154 (25%), Positives = 80/154 (51%), Gaps = 4/154 (2%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKA---LIEMEKQQQDQVDR 287
           + E+ L E+  ++ Q+   + ++   + Q      +    W+    L E EKQ ++Q ++
Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ-EQ 390

Query: 288 NIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEE 347
            +++  E++  + E  R + + M  ++ +  + E++R  +++  QE + R Q E  QEEE
Sbjct: 391 KMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE 450

Query: 348 RRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
           R R  E+  R++EE MR Q+E  +    +  EQE
Sbjct: 451 RIREREKKMREEEETMREQEEKMQKQEENMWEQE 484



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 42/160 (26%), Positives = 79/160 (49%), Gaps = 6/160 (3%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E M + +  +   EK+  + +   K +EQ  +         E +MR     E EK+ +++
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR-----EREKKMREE 725

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQ 344
            +  ++E  EK++ + E  + + + M  +++ M  QEE    ++   ++ +K  + E  Q
Sbjct: 726 -EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 784

Query: 345 EEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           E+E+   +EE  R QEE MR Q+E  +G     R QE +M
Sbjct: 785 EQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM 824



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 35/143 (24%), Positives = 77/143 (53%), Gaps = 6/143 (4%)

Query: 242 IKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEME 301
           ++ Q+  +E+E+  +  +   +E E  MR     E E++   Q +R  ++ ++  E E +
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMR-----EQEEKMWRQEERLWEQEKQMREQEQK 391

Query: 302 AARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQEE 361
               E ++    + L  ++E +R  E++  Q V+K ++ +  QE+E++ R++E + Q+EE
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQEKMWEQ-VEKMREEKKMQEQEKKTRDQEEKMQEEE 450

Query: 362 MMRRQQEGFKGTFPDAREQEIRM 384
            +R +++  +      REQE +M
Sbjct: 451 RIREREKKMREEEETMREQEEKM 473



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 64/239 (26%), Positives = 114/239 (47%), Gaps = 35/239 (14%)

Query: 164 LEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVT 223
           L  ++   G+++RA+  V  R + + + I E + +   R AL         L  +   +T
Sbjct: 171 LHHSWHFAGELQRALSAVSTRHKKADRYIEELTKE---RDALS--------LELYRNTIT 219

Query: 224 VEPMDQLDDE--EGLP----EKLVIK-NQQFHKEREQPPRFAQP----GSFEYEYAMRWK 272
            E + + + E  E LP    EK  I+ N +  K + +  +F  P     + + E   + +
Sbjct: 220 NEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 279

Query: 273 ALIEMEKQ---QQDQVDRNIKEAREK----LEMEMEAARHEHQVMLMRQDLMRRQEELRR 325
            L E EK+   Q++++ R  +  RE+     E E +  R E ++    ++L  +++ELR 
Sbjct: 280 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE 339

Query: 326 MEELHNQEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
            +EL  QE Q      ++++EE+   +EE  R+QEE M RQ+E         REQE +M
Sbjct: 340 QKELREQEEQ------MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 392



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 46/163 (28%), Positives = 81/163 (49%), Gaps = 4/163 (2%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSF-EYEYAMRWKA--LIEMEKQQ 281
           E M + +++    EK+  K Q+  K+     +  +  S  E E  MR +   + E E++ 
Sbjct: 677 EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKM 736

Query: 282 QDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLE 341
           Q+Q ++  ++  E  E E E    + + M  +Q L  ++E+L   E++  QE    ++ +
Sbjct: 737 QEQEEKMQEQEEEMWEQE-EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEK 795

Query: 342 LRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           +R +EE+ R +EE  R QEE MR Q+E   G       QE +M
Sbjct: 796 MRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKM 838



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 45/175 (25%), Positives = 91/175 (52%), Gaps = 15/175 (8%)

Query: 223 TVEPMDQLDDEEGLPE--KLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQ 280
           T +  +++ +EE + E  K + + ++  +E+E+  +  +    E E  M W+   +M++Q
Sbjct: 578 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM-WEQEEKMQEQ 636

Query: 281 QQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE-LHNQEVQKRK- 338
           ++   ++  K   ++ +M  +    E +  L   + M+ QE+++  EE +  QE  ++K 
Sbjct: 637 EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696

Query: 339 ---------QLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
                    Q ++R+EE  R RE++MR ++EEMMR Q+E  +      +EQE  M
Sbjct: 697 QEQEKKTWDQEKMREEESMREREKKMR-EEEEMMREQEEKMQEQEEKMQEQEEEM 750



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 38/228 (16%)

Query: 188 SGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQF 247
           S K  ++ + K   RK L+R     FLL         E M + ++E    EK + K ++ 
Sbjct: 239 SEKSEIQLNVKELKRK-LERAK---FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 294

Query: 248 HKEREQPPRFAQPGSFEYEYAMRW---KALIEMEKQQQDQVDRNIKEAREKLEMEMEAAR 304
              +E+  R  Q G    +    W   K L E EK+ ++Q ++ ++E +E  E E E  +
Sbjct: 295 MWRQEERLR-EQEGKMREQEEKMWRQEKRLREQEKELREQ-EKELREQKELREQE-EQMQ 351

Query: 305 HEHQVMLMRQDLMRRQEEL--RRMEELHNQEVQKRKQLE---------------LRQEEE 347
            + + M  +++ MR QEE   R+ E L  QE Q R+Q +               LR++EE
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411

Query: 348 RRRREEEM-----------RRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           R R +E+M           + Q++E   R QE         RE+E +M
Sbjct: 412 RMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKM 459



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 28/189 (14%)

Query: 223 TVEPMDQLDDEEGLPE--KLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKA------- 273
           T +  +++ +EE + E  K + + ++  +E+E+  +  +   +E E    W+        
Sbjct: 439 TRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE-EKEWQQQRLPEQK 497

Query: 274 --LIEMEKQQQDQV----------DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQE 321
             L E EK Q+ +           D+     +EK     E  R +   M  +++ MR QE
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557

Query: 322 ------ELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFP 375
                 E R  ++   QE +   Q E  +EEER R  E+  R++EEMMR Q+E  +    
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617

Query: 376 DAREQEIRM 384
             +EQE +M
Sbjct: 618 KMQEQEEKM 626



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 38/140 (27%), Positives = 73/140 (52%), Gaps = 10/140 (7%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
           + EE + ++  +  Q+    R++  R  +   +E E  MR     + E++  DQ +R  K
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR-----DQEQKMWDQEERMEK 569

Query: 291 EARE--KLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEER 348
           + +E  K   + E    E + M  R+  MR +EE+ R +E   QE +++ Q    QEE+ 
Sbjct: 570 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ---EQEEKM 626

Query: 349 RRREEEMRRQQEEMMRRQQE 368
             +EE+M+ Q+E+M  ++++
Sbjct: 627 WEQEEKMQEQEEKMWEQEEK 646



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 36/148 (24%), Positives = 79/148 (53%), Gaps = 2/148 (1%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E M + ++E    E+ + + ++   E+++ P   +   +E+E     + + E E++ +DQ
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK-LWEHEKMQEQEKIWEQEEKMRDQ 799

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQ 344
            ++ ++   EK+  + E  R + + M  +++ M  QEE    +E      +++ + +++ 
Sbjct: 800 EEK-MRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQG 858

Query: 345 EEERRRREEEMRRQQEEMMRRQQEGFKG 372
           +EE+ R +EE  R QEE MR Q+E  +G
Sbjct: 859 QEEKMREQEEKMRGQEEKMREQEEKMRG 886



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 42/174 (24%), Positives = 80/174 (45%), Gaps = 20/174 (11%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
           D EE + E+     ++  + REQ   + Q      E  M+ +     +++++ Q +  I+
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453

Query: 291 EAREKLEMEMEAARHEHQVMLMRQDLMRRQEELR--------RMEELHNQEVQKRKQLEL 342
           E  +K+  E E  R + + M  +++ M  QEE          + E+L  QE  + ++ ++
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 513

Query: 343 RQEEERRRREEEM------------RRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
            ++EE+ R +EEM             R+QE+ M  Q+E  +       +QE RM
Sbjct: 514 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 567



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 42/153 (27%), Positives = 74/153 (48%), Gaps = 11/153 (7%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMR------WKALIEME 278
           E  ++L ++E + E+     +Q  K R+Q   + Q      +  MR      W+   +M 
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554

Query: 279 KQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE--LHNQEVQK 336
            Q+Q   D+  +E  EK   E E    + +  +  ++ MR +E+  R EE  +  QE + 
Sbjct: 555 DQEQKMWDQ--EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 612

Query: 337 RKQLELRQEEERRR-REEEMRRQQEEMMRRQQE 368
           ++Q E  QE+E +   +EE  ++QEE M  Q+E
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 44/161 (27%), Positives = 77/161 (47%), Gaps = 7/161 (4%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
           ++EE + E+     +Q  K +EQ     +     +E   +      + +Q++   +    
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 783

Query: 291 EAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE--LHNQEVQKRKQLELR--QEE 346
           + +EK+  + E  R + + M  +++ MR QEE  R +E  +  QE +   Q E    QEE
Sbjct: 784 QEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE 843

Query: 347 ERRRREEEMRRQ---QEEMMRRQQEGFKGTFPDAREQEIRM 384
           +   +EE+M  +   QEE MR Q+E  +G     REQE +M
Sbjct: 844 KMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKM 884



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 38/158 (24%), Positives = 82/158 (51%), Gaps = 13/158 (8%)

Query: 224 VEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQD 283
           +E   Q  +++   ++  ++ ++  +ERE+  R       E E  MR     E E++ Q+
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMR-------EEEEMMR-----EQEEKMQE 614

Query: 284 QVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELR 343
           Q ++ ++E  EK+  + E  + + + M  +++ M  QEE    ++   ++ +K  + E  
Sbjct: 615 QEEK-MQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 673

Query: 344 QEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
           QE+E+ + +EE   +QE+M ++ QE  K T+   + +E
Sbjct: 674 QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 40/171 (23%), Positives = 88/171 (51%), Gaps = 12/171 (7%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E M + +++    E+ + + ++  +E+EQ  R  +   +E +  +R K   E   ++Q++
Sbjct: 362 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK---EERMREQEK 418

Query: 285 VDRNIKEAREKLEM-EMEAARHEHQVMLMRQDLMRRQEELRRMEE--LHNQEVQKRKQLE 341
           +   +++ RE+ +M E E    + +  +  ++ +R +E+  R EE  +  QE + +KQ E
Sbjct: 419 MWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 478

Query: 342 -LRQEEERRRREEEMRRQQE-----EMMRRQQEGFKGTFPDAREQEIRMGQ 386
            + ++EE+  +++ +  Q+E     E M+ Q+E         R+QE   GQ
Sbjct: 479 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 529



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 41/156 (26%), Positives = 69/156 (44%), Gaps = 21/156 (13%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
           + EE + E+     +Q  K  EQ  +  +      +    W    E EK Q+ +    ++
Sbjct: 628 EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW----EHEKMQEQE---KMQ 680

Query: 291 EAREKL--EMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEER 348
           E  EK+  + +ME    E +     Q+ MR +E +R  E+            ++R+EEE 
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK------------KMREEEEM 728

Query: 349 RRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
            R +EE  ++QEE M+ Q+E          EQE +M
Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 43/130 (33%), Positives = 76/130 (58%), Gaps = 22/130 (16%)

Query: 276 EMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEEL--------RRME 327
           E E++ Q+Q ++ I+E  EK+  + E  R + ++M  +++ MRRQEE+        RR+E
Sbjct: 311 EWEEKIQEQEEK-IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE 369

Query: 328 ELHNQEVQKRKQLE--------LRQEEERRR-----REEEMRRQQEEMMRRQQEGFKGTF 374
           E+  ++ +K ++LE        +R++EE+R+     RE+E R++QE  M RQ+E  +   
Sbjct: 370 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 429

Query: 375 PDAREQEIRM 384
              REQE +M
Sbjct: 430 EKIREQEKKM 439



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 41/140 (29%), Positives = 77/140 (55%), Gaps = 2/140 (1%)

Query: 243 KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEA 302
           K Q+  K REQ  R  Q     +    + +   E  ++Q+ ++ R  ++  E+ ++  E 
Sbjct: 398 KRQEEEKIREQEKRQEQEAKM-WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 456

Query: 303 ARHEHQVMLMRQDLMRRQEEL-RRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQEE 361
            R E + M  +++ +R QEE+ R+ E++H QE  ++++ ++ ++EE+   +EE  R+QEE
Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516

Query: 362 MMRRQQEGFKGTFPDAREQE 381
            M RQ+E  +      REQE
Sbjct: 517 KMWRQEEKIREQEEKIREQE 536



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 38/140 (27%), Positives = 73/140 (52%), Gaps = 1/140 (0%)

Query: 243 KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEA 302
           K  +  K RE+  R  Q   +  E  +R +  I  +K++  + ++  K+  +    E + 
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504

Query: 303 ARHEHQVMLMRQDLMRRQEELRRMEE-LHNQEVQKRKQLELRQEEERRRREEEMRRQQEE 361
              E ++    + + R++E++R  EE +  QE + R+Q E+ QE+E +  E+E + Q++E
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564

Query: 362 MMRRQQEGFKGTFPDAREQE 381
            MRRQ+E  +      REQ+
Sbjct: 565 KMRRQEEKIREQEEKIREQK 584



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 42/164 (25%), Positives = 86/164 (52%), Gaps = 4/164 (2%)

Query: 224 VEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSF-EYEYAMRWKALIEMEKQQQ 282
           +   +++ +EE   E+  +  Q+  K REQ   + Q     E E   + +  +  ++++ 
Sbjct: 446 IHEQEKIREEEKRQEQEEMWRQE-EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504

Query: 283 DQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE--LHNQEVQKRKQL 340
              +  I+E  EK+  + E  R + + +  +++ +R QEE+ + +E  +  QE + ++Q 
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564

Query: 341 ELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           ++R++EE+ R +EE  R+Q+E +R Q+E         REQE  M
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMM 608



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 35/149 (23%), Positives = 81/149 (54%), Gaps = 2/149 (1%)

Query: 233 EEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEA 292
           EE + E+  I+ Q+  ++R++  +  +    + + A  W+   ++ +Q++   ++  K  
Sbjct: 383 EEKMHEQEKIREQE--EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440

Query: 293 REKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRRE 352
           R++ ++  +    E +    ++++ R++E++R  EE+  Q+ +  +Q ++R++EE+  R+
Sbjct: 441 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ 500

Query: 353 EEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
           EE    QEE +R Q+E         REQE
Sbjct: 501 EEKMHDQEEKIREQEEKMWRQEEKIREQE 529



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 43/156 (27%), Positives = 85/156 (54%), Gaps = 7/156 (4%)

Query: 233 EEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEK--QQQDQV---DR 287
           EE + E+  I+ ++  +E+E+  R  +    + E   + + + E EK  +Q+++V   + 
Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE 502

Query: 288 NIKEAREKL-EMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKR-KQLELRQE 345
            + +  EK+ E E +  R E ++    + +  ++E++R  EE+  ++ +K  +Q E  QE
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE 562

Query: 346 EERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
           +E+ RR+EE  R+QEE +R Q+E  +       EQE
Sbjct: 563 QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 46/158 (29%), Positives = 82/158 (51%), Gaps = 13/158 (8%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
           D EE + E+     +Q  K REQ  +       E E  +R     E E+  Q+Q ++ + 
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIR-----EQEEKIR-----EQEEMMQEQEEK-MG 554

Query: 291 EAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE-LHNQEVQKRKQLELRQEEERR 349
           E  EK++ + +  R E ++    + +  ++E++R  EE +  QE + R+Q E+ QE+E +
Sbjct: 555 EQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614

Query: 350 RREEEMRR-QQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
             E+E +  +QEE M+ Q+E  +       EQE+R+ Q
Sbjct: 615 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 652



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 44/157 (28%), Positives = 81/157 (51%), Gaps = 6/157 (3%)

Query: 233 EEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEA 292
           +E + E+  I+ Q+    R++     Q      +    W+   E  ++Q++++    ++ 
Sbjct: 481 KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE-EKIREQEEKIREQEEKI 539

Query: 293 REKLEM--EMEAARHEHQVMLMRQDLMRRQEE-LRRMEELHNQEVQKRKQLELR--QEEE 347
           RE+ EM  E E    E +  +  Q+ MRRQEE +R  EE   ++ +K ++ E +  ++EE
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599

Query: 348 RRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           + R +EEM ++QEE M  Q+E         +EQE +M
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 35/149 (23%), Positives = 81/149 (54%), Gaps = 8/149 (5%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E + + +++    E+ + + ++  +E+E+  R  +    E E  M  +     E+++  +
Sbjct: 509 EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRR 568

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQ 344
            +  I+E  EK+  + E  R + + +  +++ +R QEE+ + +E   +++ ++++    Q
Sbjct: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE---EKMWEQEEKMCEQ 625

Query: 345 EEERRRREEEMRRQQEEMMR-----RQQE 368
           EE+ + +EE+MRRQ+E+M       RQQE
Sbjct: 626 EEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 39/166 (23%), Positives = 86/166 (51%), Gaps = 9/166 (5%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQ-D 283
           E + + +++    E+ + + ++  +E+E+  R  +   +E E  MR +  +  EK+++  
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366

Query: 284 QVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELR 343
           +++  + E  EK+  E+E   HE + +  +++  + +E++R  E+   QE +  +Q E  
Sbjct: 367 RLEEMMWEKEEKIR-ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425

Query: 344 QEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAM 389
           +E+E + RE+E +  ++E    +QE         RE+E R  Q  M
Sbjct: 426 REQEEKIREQEKKMWRQEEKIHEQE-------KIREEEKRQEQEEM 464



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 35/131 (26%), Positives = 71/131 (54%), Gaps = 8/131 (6%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           E+ + + ++   E+E+  R  +   +E E  +R     E+E++  +Q    I+E  EK +
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIR-----ELEEKMHEQ--EKIREQEEKRQ 400

Query: 298 MEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRR 357
            E E  R + +       + R++E++R  EE   ++ +K  + E +  E+ + REEE R+
Sbjct: 401 EE-EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 459

Query: 358 QQEEMMRRQQE 368
           +QEEM R++++
Sbjct: 460 EQEEMWRQEEK 470



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 32/134 (23%), Positives = 75/134 (55%), Gaps = 3/134 (2%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           E+ + + ++  +E+E+  +  +    E E  M+ +  +  ++++  + +  I+E +EK+ 
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIR 588

Query: 298 MEMEAARHEHQVMLMRQDLMRRQEE--LRRMEELHNQEVQKRKQLELRQEEERRRREEEM 355
            + E    + + +  ++++M+ QEE    + E++  QE + ++Q E  + +E +  E+E+
Sbjct: 589 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 648

Query: 356 R-RQQEEMMRRQQE 368
           R RQQEE M+  QE
Sbjct: 649 RLRQQEEKMQEHQE 662



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 19/129 (14%)

Query: 275 IEMEKQQQDQVDRNIKEAREKLE----------MEMEAARHEHQVMLMRQDLMRRQEELR 324
           +++ + ++ ++  N+KE + KLE          ++ EA     ++  +   L  + EE  
Sbjct: 230 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 289

Query: 325 RMEELHNQEVQKRKQLE---------LRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFP 375
               L+ Q+ +K  + E         ++++EE+ R +EE  R+QEE MRRQ+E       
Sbjct: 290 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 349

Query: 376 DAREQEIRM 384
             R QE  M
Sbjct: 350 KMRRQEEMM 358



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 33/125 (26%), Positives = 63/125 (50%), Gaps = 9/125 (7%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E M + +++ G  E+   K Q+  K R Q  +  +    + E     K  I  ++++  +
Sbjct: 544 EMMQEQEEKMGEQEE---KMQEQEKMRRQEEKIRE----QEEKIREQKEKIREQEEKIWE 596

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEE-LRRMEE-LHNQEVQKRKQLEL 342
            +  I+E  E ++ + E    + + M  +++ M+ QEE +RR EE +  QEV+ R+Q E 
Sbjct: 597 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656

Query: 343 RQEEE 347
            QE +
Sbjct: 657 MQEHQ 661



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 23/133 (17%)

Query: 275 IEMEKQQQDQVDRNIKEAREKLEMEMEAARHE-HQVMLMRQDLMRRQEELRRM------- 326
           + +E  +    D  +KE   KL+ +++    E  ++ L  ++L R+ E  + +       
Sbjct: 205 LSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 264

Query: 327 -------EELHNQEVQKRKQLE--------LRQEEERRRREEEMRRQQEEMMRRQQEGFK 371
                  +EL +   + + Q+E         +Q+EE+  R+EE  ++ EE ++ Q+E  +
Sbjct: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324

Query: 372 GTFPDAREQEIRM 384
                 REQE +M
Sbjct: 325 EQEEKIREQEEKM 337



 Score = 33.1 bits (74), Expect = 0.56
 Identities = 22/109 (20%), Positives = 54/109 (49%), Gaps = 3/109 (2%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E  +++ ++E +  +     +Q  K REQ  +  +     +E   + +   EM ++Q+++
Sbjct: 555 EQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614

Query: 285 V---DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELH 330
           +   +  + E  EK++ + E  R + + M  ++  +R+QEE  +  + H
Sbjct: 615 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 663


>gi|13899354 RNA binding motif protein 4B [Homo sapiens]
          Length = 359

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 6/112 (5%)

Query: 75  RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPL 134
           +LF+GNLP + TE+E+R LFE+YGK  E  I K+  +GF+ +E +T AE A   L +  L
Sbjct: 3   KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--YGFVHIEDKTAAEDAIRNLHHYKL 60

Query: 135 RGKQLRVRFACH----SASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVD 182
            G  + V  + +    S  L V N+    +N+ L   F  +G V    ++ D
Sbjct: 61  HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD 112



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 2/71 (2%)

Query: 74  SRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMP 133
           ++L VGN+ P  T +E+R  FE+YG   E  I KD  + F+ +E    A  A   LDN  
Sbjct: 78  TKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--YAFVHMERAEDAVEAIRGLDNTE 135

Query: 134 LRGKQLRVRFA 144
            +GK++ V+ +
Sbjct: 136 FQGKRMHVQLS 146


>gi|93277122 RNA binding motif protein 4 [Homo sapiens]
          Length = 364

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 6/112 (5%)

Query: 75  RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPL 134
           +LF+GNLP + TE+E+R LFE+YGK  E  I K+  +GF+ +E +T AE A   L +  L
Sbjct: 3   KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--YGFVHIEDKTAAEDAIRNLHHYKL 60

Query: 135 RGKQLRVRFACH----SASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVD 182
            G  + V  + +    S  L V N+    +N+ L   F  +G V    ++ D
Sbjct: 61  HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKD 112



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 2/71 (2%)

Query: 74  SRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMP 133
           ++L VGN+ P  T +E+R  FE+YG   E  I KD  + F+ +E    A  A   LDN  
Sbjct: 78  TKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKD--YAFVHMERAEDAVEAIRGLDNTE 135

Query: 134 LRGKQLRVRFA 144
            +GK++ V+ +
Sbjct: 136 FQGKRMHVQLS 146


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 42/150 (28%), Positives = 80/150 (53%), Gaps = 8/150 (5%)

Query: 239 KLVIKNQQFHKEREQPPRFAQPGSFEYEYAMR----WKALIEMEKQQQDQVDRNIKEARE 294
           KL++  QQ   E +   +  Q  S + +  +     W  L + ++++  + +  I+E  E
Sbjct: 255 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 314

Query: 295 KLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEE 354
           K++ + E  R + + +  +++ MRRQEE+   +E    E  +R++  + ++EE+ RR+EE
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE----EKMRRQEEMMWEKEEKMRRQEE 370

Query: 355 MRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           M  ++EE MRRQ+E         RE E +M
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEKIRELEEKM 400



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 45/144 (31%), Positives = 78/144 (54%), Gaps = 15/144 (10%)

Query: 249 KEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQ 308
           +E+E+  R  +    E E  MR +  +  EK+++      ++   E +  + E  R + +
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK------MRRQEEMMWEKEEKMRRQEE 370

Query: 309 VMLMRQDLMRRQEEL--------RRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE 360
           +M  +++ MRRQEE+        R +EE  +++ + R+Q E RQEEE+ R E+E R++QE
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR-EQEKRQEQE 429

Query: 361 EMMRRQQEGFKGTFPDAREQEIRM 384
             M RQ+E  +      REQE +M
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKM 453



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 46/154 (29%), Positives = 83/154 (53%), Gaps = 5/154 (3%)

Query: 233 EEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEA 292
           EE + E+  I+ ++  +E+E+  R  +    E E   R K  +  ++++  + +  +   
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWR-QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515

Query: 293 REKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE-LHNQEVQKRKQLELRQEEERRR- 350
            EK+  + E  R + + M  +++ +R QEE+ R EE +H QE  K  + E RQE+E +  
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE--KIWEEEKRQEQEDKMW 573

Query: 351 REEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           R+EE  R+QEE + RQ+E  +      +EQE +M
Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 41/122 (33%), Positives = 69/122 (56%), Gaps = 11/122 (9%)

Query: 276 EMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEEL--------RRME 327
           E E++ Q+Q ++ I+E  EK+  + E  R + ++M  +++ MRRQEE+        RR E
Sbjct: 311 EWEEKIQEQEEK-IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 369

Query: 328 E-LHNQEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
           E +  +E + R+Q E+  E+E + RE E +  ++E +R Q+E  +      REQE R  Q
Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK-RQEEEKIREQEKRQEQ 428

Query: 387 MA 388
            A
Sbjct: 429 EA 430



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 38/162 (23%), Positives = 87/162 (53%), Gaps = 6/162 (3%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E M + +++    E+ V + ++  +E+E+  R  +   +  E  +R +  +  E+++  +
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQ 344
            ++ I E  ++ E E +  R E ++    + + R++E++R  EE   ++ +K     + +
Sbjct: 556 QEK-IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK-----MWK 609

Query: 345 EEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQ 386
           +EE+ R +EE  ++QEE +R Q+E  +      +EQE +MG+
Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 42/166 (25%), Positives = 86/166 (51%), Gaps = 8/166 (4%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E M + +++    E+++ + ++  +E E+     +    + E     + + E EK+Q+ +
Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429

Query: 285 V-----DRNIKEAREKL-EMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRK 338
                 +  I+E  EK+ E E +  R E ++    Q+ +R +E+ +  EE+  QE +  +
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIH--EQEKIREEEKRQEQEEMWRQEEKIHE 487

Query: 339 QLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           Q E+ +++E+   +EE  R+QEE + RQ+E  +      REQE +M
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKM 533



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 41/147 (27%), Positives = 83/147 (56%), Gaps = 10/147 (6%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           E+ V + ++  +E+E+  +  +   ++ E  +R     E E++ Q+Q ++ I+E  EK+ 
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR-----EQEEKIQEQEEK-IREQEEKIR 636

Query: 298 MEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRR 357
            + E  + + + M  +++ M  QEE  +M+E   +E   R++ ++R++E++ R +EE  R
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEE--KMQE--QEETMWRQEEKIREQEKKIREQEEKIR 692

Query: 358 QQEEMMRRQQEGFKGTFPDAREQEIRM 384
           +QEEMM+ Q+E          EQE +M
Sbjct: 693 EQEEMMQEQEEKMWEQEEKMCEQEEKM 719



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 38/152 (25%), Positives = 75/152 (49%), Gaps = 3/152 (1%)

Query: 233 EEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK-- 290
           EE + E+     +Q  K REQ  +  +     +E   + +   EM  ++++++ R  +  
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 372

Query: 291 -EAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERR 349
            E  EK+  + E    + + +   ++ M  QE++R  EE   +E + R+Q + +++E + 
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432

Query: 350 RREEEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
            R+EE  R+QEE +R Q++          EQE
Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 464



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 40/163 (24%), Positives = 87/163 (53%), Gaps = 9/163 (5%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E + + +++    E+ + K ++  +E+E+  +  +    E E  +R     E E+  Q+Q
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR-----EQEEMTQEQ 645

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEE-LRRMEEL--HNQEVQKRKQLE 341
            ++ + E  EK+  + E  + + + M  +++ +R QE+ +R  EE     +E+ + ++ +
Sbjct: 646 EEK-MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 704

Query: 342 LRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           + ++EE+   +EE  ++QEE MRRQ+E         R+QE +M
Sbjct: 705 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 36/152 (23%), Positives = 76/152 (50%), Gaps = 7/152 (4%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           E+ + + ++   E+E+  R  +   +E E  MR +  +  EK+++ +    +   +E+  
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 393

Query: 298 MEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRR 357
            E+E   HE + +  +++  + +E++R  E+   QE +  +Q E  +E+E + RE+E + 
Sbjct: 394 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 453

Query: 358 QQEEMMRRQQEGFKGTFPDAREQEIRMGQMAM 389
            ++E    +QE         RE+E R  Q  M
Sbjct: 454 WRQEEKIHEQE-------KIREEEKRQEQEEM 478



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 42/135 (31%), Positives = 72/135 (53%), Gaps = 10/135 (7%)

Query: 243 KNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEA 302
           K Q+  K REQ  R  Q     +    + +   E  ++Q+ ++ R  ++  E+ ++  E 
Sbjct: 412 KRQEEEKIREQEKRQEQEAKM-WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470

Query: 303 ARHEHQVMLMRQDLMRRQEEL-RRMEELHNQEVQKRKQLEL--RQEE-----ERRRREEE 354
            R E + M  +++ +  QEE+ R+ E++H QE + RKQ E   RQEE     E + RE+E
Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530

Query: 355 MRR-QQEEMMRRQQE 368
            +  +QEE +R Q+E
Sbjct: 531 EKMWRQEEKIREQEE 545



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 49/171 (28%), Positives = 82/171 (47%), Gaps = 23/171 (13%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
           + EE + E+     +Q  K REQ   + +     +E    W+   E  ++Q+D++ R  +
Sbjct: 521 EQEEKIREQEEKMWRQEEKIREQEEMWREEEKM-HEQEKIWEE--EKRQEQEDKMWRQEE 577

Query: 291 EAREKLEM---------EMEAARHEHQVMLMRQD-LMRRQEE--LRRMEELHNQEVQKRK 338
           + RE+ E          E E  R E +  + +Q+  +R QEE    + E++  QE + R+
Sbjct: 578 KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE 637

Query: 339 QLELRQEEERRRRE--------EEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
           Q E+ QE+E +  E        EE  ++QEE M RQ+E  +      REQE
Sbjct: 638 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 19/129 (14%)

Query: 275 IEMEKQQQDQVDRNIKEAREKLE----------MEMEAARHEHQVMLMRQDLMRRQEELR 324
           +++ + ++ ++  N+KE + KLE          ++ EA     ++  +   L  + EE  
Sbjct: 230 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 289

Query: 325 RMEELHNQEVQKRKQLE---------LRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFP 375
               L+ Q+ +K  + E         ++++EE+ R +EE  R+QEE MRRQ+E       
Sbjct: 290 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 349

Query: 376 DAREQEIRM 384
             R QE  M
Sbjct: 350 KMRRQEEMM 358



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 34/134 (25%), Positives = 74/134 (55%), Gaps = 8/134 (5%)

Query: 238 EKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLE 297
           E+ + + ++   E+E+  R  +   +E E  +R    +E +  +Q+++    ++ +E+ +
Sbjct: 362 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEK 418

Query: 298 MEMEAARHEHQVMLMRQD-LMRRQEELRRMEE--LHNQEVQKRKQLELRQEEERRRREEE 354
           +  +  R E +  + RQ+  +R QEE  R +E  +  QE +  +Q ++R+EE  +R+E+E
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE--KRQEQE 476

Query: 355 MRRQQEEMMRRQQE 368
              +QEE +  Q+E
Sbjct: 477 EMWRQEEKIHEQEE 490



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 23/133 (17%)

Query: 275 IEMEKQQQDQVDRNIKEAREKLEMEMEAARHE-HQVMLMRQDLMRRQEELRRM------- 326
           + +E  +    D  +KE   KL+ +++    E  ++ L  ++L R+ E  + +       
Sbjct: 205 LSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 264

Query: 327 -------EELHNQEVQKRKQLE--------LRQEEERRRREEEMRRQQEEMMRRQQEGFK 371
                  +EL +   + + Q+E         +Q+EE+  R+EE  ++ EE ++ Q+E  +
Sbjct: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324

Query: 372 GTFPDAREQEIRM 384
                 REQE +M
Sbjct: 325 EQEEKIREQEEKM 337


>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
          Length = 380

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 51/182 (28%), Positives = 90/182 (49%), Gaps = 17/182 (9%)

Query: 40  PIPANGQQASSQNEGLTIDLKNFRKP---GEKTFTQRSRLFVGNLPPDITEEEMRKLFEK 96
           P  +NG  +++ N G + + +N   P   G  T   ++ L V  LP ++T+EE R LF  
Sbjct: 10  PQVSNGPTSNTSN-GPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGS 68

Query: 97  YGKAGEVFIHKDK------GFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFA------ 144
            G+     + +DK      G+GF+       AE A   L+ + L+ K ++V +A      
Sbjct: 69  IGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSAS 128

Query: 145 CHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDD-RGRPSGKGIVEFSGKPAARK 203
              A+L V  LP+ ++ + LE+ FS +G++  + ++VD   G   G G + F  +  A +
Sbjct: 129 IRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEE 188

Query: 204 AL 205
           A+
Sbjct: 189 AI 190



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 6/79 (7%)

Query: 76  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTLAEIAKVEL 129
           +FV NL PD  E  + +LF  +G    V + +D      KGFGF+ +     A +A   L
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358

Query: 130 DNMPLRGKQLRVRFACHSA 148
           +   L  + L+V F  + A
Sbjct: 359 NGYRLGDRVLQVSFKTNKA 377


>gi|38201714 ELAV-like 1 [Homo sapiens]
          Length = 326

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 43/146 (29%), Positives = 76/146 (52%), Gaps = 13/146 (8%)

Query: 73  RSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDK------GFGFIRLETRTLAEIAK 126
           R+ L V  LP ++T++E+R LF   G+     + +DK      G+GF+   T   AE A 
Sbjct: 19  RTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAI 78

Query: 127 VELDNMPLRGKQLRVRFACHS------ASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI 180
             L+ + L+ K ++V +A  S      A+L +  LP+ ++ + +E+ FS FG++  + V+
Sbjct: 79  NTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138

Query: 181 VDD-RGRPSGKGIVEFSGKPAARKAL 205
           VD   G   G   + F  +  A +A+
Sbjct: 139 VDQTTGLSRGVAFIRFDKRSEAEEAI 164



 Score = 32.3 bits (72), Expect = 0.95
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 6/74 (8%)

Query: 76  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTLAEIAKVEL 129
           +F+ NL  D  E  + ++F  +G    V + +D      KGFGF+ +     A +A   L
Sbjct: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305

Query: 130 DNMPLRGKQLRVRF 143
           +   L  K L+V F
Sbjct: 306 NGYRLGDKILQVSF 319


>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
          Length = 369

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 51/182 (28%), Positives = 90/182 (49%), Gaps = 17/182 (9%)

Query: 40  PIPANGQQASSQNEGLTIDLKNFRKP---GEKTFTQRSRLFVGNLPPDITEEEMRKLFEK 96
           P  +NG  +++ N G + + +N   P   G  T   ++ L V  LP ++T+EE R LF  
Sbjct: 13  PQVSNGPTSNTSN-GPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGS 71

Query: 97  YGKAGEVFIHKDK------GFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFA------ 144
            G+     + +DK      G+GF+       AE A   L+ + L+ K ++V +A      
Sbjct: 72  IGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSAS 131

Query: 145 CHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDD-RGRPSGKGIVEFSGKPAARK 203
              A+L V  LP+ ++ + LE+ FS +G++  + ++VD   G   G G + F  +  A +
Sbjct: 132 IRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEE 191

Query: 204 AL 205
           A+
Sbjct: 192 AI 193



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 6/79 (7%)

Query: 76  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTLAEIAKVEL 129
           +FV NL PD  E  + +LF  +G    V + +D      KGFGF+ +     A +A   L
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347

Query: 130 DNMPLRGKQLRVRFACHSA 148
           +   L  + L+V F  + A
Sbjct: 348 NGYRLGDRVLQVSFKTNKA 366


>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
          Length = 366

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 51/182 (28%), Positives = 90/182 (49%), Gaps = 17/182 (9%)

Query: 40  PIPANGQQASSQNEGLTIDLKNFRKP---GEKTFTQRSRLFVGNLPPDITEEEMRKLFEK 96
           P  +NG  +++ N G + + +N   P   G  T   ++ L V  LP ++T+EE R LF  
Sbjct: 10  PQVSNGPTSNTSN-GPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGS 68

Query: 97  YGKAGEVFIHKDK------GFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFA------ 144
            G+     + +DK      G+GF+       AE A   L+ + L+ K ++V +A      
Sbjct: 69  IGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSAS 128

Query: 145 CHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDD-RGRPSGKGIVEFSGKPAARK 203
              A+L V  LP+ ++ + LE+ FS +G++  + ++VD   G   G G + F  +  A +
Sbjct: 129 IRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEE 188

Query: 204 AL 205
           A+
Sbjct: 189 AI 190



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 6/79 (7%)

Query: 76  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTLAEIAKVEL 129
           +FV NL PD  E  + +LF  +G    V + +D      KGFGF+ +     A +A   L
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344

Query: 130 DNMPLRGKQLRVRFACHSA 148
           +   L  + L+V F  + A
Sbjct: 345 NGYRLGDRVLQVSFKTNKA 363


>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
          Length = 383

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 51/182 (28%), Positives = 90/182 (49%), Gaps = 17/182 (9%)

Query: 40  PIPANGQQASSQNEGLTIDLKNFRKP---GEKTFTQRSRLFVGNLPPDITEEEMRKLFEK 96
           P  +NG  +++ N G + + +N   P   G  T   ++ L V  LP ++T+EE R LF  
Sbjct: 27  PQVSNGPTSNTSN-GPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGS 85

Query: 97  YGKAGEVFIHKDK------GFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFA------ 144
            G+     + +DK      G+GF+       AE A   L+ + L+ K ++V +A      
Sbjct: 86  IGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSAS 145

Query: 145 CHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDD-RGRPSGKGIVEFSGKPAARK 203
              A+L V  LP+ ++ + LE+ FS +G++  + ++VD   G   G G + F  +  A +
Sbjct: 146 IRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEE 205

Query: 204 AL 205
           A+
Sbjct: 206 AI 207



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 6/79 (7%)

Query: 76  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTLAEIAKVEL 129
           +FV NL PD  E  + +LF  +G    V + +D      KGFGF+ +     A +A   L
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361

Query: 130 DNMPLRGKQLRVRFACHSA 148
           +   L  + L+V F  + A
Sbjct: 362 NGYRLGDRVLQVSFKTNKA 380


>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
          Length = 366

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 51/182 (28%), Positives = 90/182 (49%), Gaps = 17/182 (9%)

Query: 40  PIPANGQQASSQNEGLTIDLKNFRKP---GEKTFTQRSRLFVGNLPPDITEEEMRKLFEK 96
           P  +NG  +++ N G + + +N   P   G  T   ++ L V  LP ++T+EE R LF  
Sbjct: 10  PQVSNGPTSNTSN-GPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGS 68

Query: 97  YGKAGEVFIHKDK------GFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFA------ 144
            G+     + +DK      G+GF+       AE A   L+ + L+ K ++V +A      
Sbjct: 69  IGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSAS 128

Query: 145 CHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDD-RGRPSGKGIVEFSGKPAARK 203
              A+L V  LP+ ++ + LE+ FS +G++  + ++VD   G   G G + F  +  A +
Sbjct: 129 IRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEE 188

Query: 204 AL 205
           A+
Sbjct: 189 AI 190



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 6/79 (7%)

Query: 76  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTLAEIAKVEL 129
           +FV NL PD  E  + +LF  +G    V + +D      KGFGF+ +     A +A   L
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344

Query: 130 DNMPLRGKQLRVRFACHSA 148
           +   L  + L+V F  + A
Sbjct: 345 NGYRLGDRVLQVSFKTNKA 363


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 61/207 (29%), Positives = 105/207 (50%), Gaps = 11/207 (5%)

Query: 188 SGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQF 247
           S K  ++ + K   RK L+R     FLL         E M + ++E    EK + K ++ 
Sbjct: 201 SEKSEIQLNVKELKRK-LERAK---FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 256

Query: 248 HKEREQPPRFAQPGSFEYEYAMRW--KALIEMEKQQQDQVDRNIKEAREKLEMEMEAARH 305
              +E+  R  +    E E  MR   K L E EK+ ++Q ++ ++E ++KL  + E  + 
Sbjct: 257 MWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQ-EKELRE-QKKLREQEEQMQE 314

Query: 306 EHQVMLMRQDLMRRQEEL--RRMEELHNQEVQKRKQLE-LRQEEERRRREEEMRRQQEEM 362
           + + M  +++ MR QEE   R+ E L  QE Q R+Q + +R +EER   ++E  R++EE 
Sbjct: 315 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 374

Query: 363 MRRQQEGFKGTFPDAREQEIRMGQMAM 389
           MR Q++ ++       E+ IR  +  M
Sbjct: 375 MREQEKMWEQEEKMQEEERIREREKKM 401



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 44/162 (27%), Positives = 86/162 (53%), Gaps = 3/162 (1%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKA--LIEMEKQQQ 282
           E  ++L ++E + E+     +Q  K R+Q   + Q      +  MR +   + E E++ +
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496

Query: 283 DQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLEL 342
           DQ ++ + +  E++  + E  R + + M  ++ + +++E++R  ++   QE +   Q E 
Sbjct: 497 DQ-EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK 555

Query: 343 RQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
            +EEER R  E+  R++EEMMR Q+E  +      REQE +M
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 44/160 (27%), Positives = 87/160 (54%), Gaps = 15/160 (9%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E   Q  +++   ++  ++ ++  +ERE+  R       E E  MR     E E++ Q+Q
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMR-------EEEEMMR-----EQEEKMQEQ 586

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQ 344
            ++ ++E  EK+  + E  + + + M  +++ M  QEE  +M+E   +E+   ++ ++++
Sbjct: 587 EEK-MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE--QEEMMWEQEEKMQE 643

Query: 345 EEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           +EE+   +EE  R+QEE MR Q+E  +G     REQE +M
Sbjct: 644 QEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 33/127 (25%), Positives = 70/127 (55%), Gaps = 5/127 (3%)

Query: 242 IKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEME 301
           ++ Q+  +E+E+  +  +   +E E  MR     E E++   Q +R  ++ ++  E E +
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMR-----EQEEKMWRQEERLWEQEKQMREQEQK 353

Query: 302 AARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQEE 361
               E ++    + L  ++E +R  E++  QE + +++  +R+ E++ R EEE  R+QEE
Sbjct: 354 MRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEE 413

Query: 362 MMRRQQE 368
            M++Q+E
Sbjct: 414 KMQKQEE 420



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 52/166 (31%), Positives = 78/166 (46%), Gaps = 17/166 (10%)

Query: 233 EEGLPEKLVIKNQQFHKEREQPPRFAQPGSF--EYEYAMR-WKALIEMEKQQQDQVDR-- 287
           EE L E+     +Q  K R Q  R  +      E E  +R  K L E E+Q Q+Q ++  
Sbjct: 261 EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMW 320

Query: 288 ----NIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEE--------LRRMEELHNQEVQ 335
                ++E  EK+  + E    + + M  ++  MR QEE        LR  EE   ++ +
Sbjct: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 380

Query: 336 KRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
             +Q E  QEEER R  E+  R++EE MR Q+E  +    +  EQE
Sbjct: 381 MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 80/164 (48%), Gaps = 15/164 (9%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDR--- 287
           D EE + E+     ++  + REQ   + Q      E     K   E EK+  DQ ++   
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREE-----KKTQEQEKKTWDQEEKMRE 558

Query: 288 --NIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEEL-----RRMEELHNQEVQKRKQL 340
              ++E  +K+  E E  R + + M  +++ MR QEE       +M+E   +  ++ +++
Sbjct: 559 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 618

Query: 341 ELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
             ++EE++ + +EEM  +QEE M+ Q+E         REQE +M
Sbjct: 619 WEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 48/161 (29%), Positives = 83/161 (51%), Gaps = 7/161 (4%)

Query: 231 DDEEGLPEKLVIKNQQFH-KEREQPPRFAQPGSFEYEYAMRWKA--LIEMEKQQQDQVDR 287
           D EE + E+  ++ ++   +E E+  R  +    E E  MR +   + E E++ Q+Q ++
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610

Query: 288 NIKEAREKLEMEMEAARHEHQVMLMRQD-LMRRQEEL--RRMEELHNQEVQKRKQLELRQ 344
             ++  +  E E E    E + M+  Q+  M+ QEE    + E++  QE + R+Q E  Q
Sbjct: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670

Query: 345 EEERRRREEEMRRQ-QEEMMRRQQEGFKGTFPDAREQEIRM 384
            +E + RE+E + Q QEE MR Q+E  +G       QE +M
Sbjct: 671 GQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 44/161 (27%), Positives = 82/161 (50%), Gaps = 9/161 (5%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPR-FAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNI 289
           ++EE + E+     +Q  K REQ  + + Q    + +    W+   + EK  + + +  +
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE---QEEKMWEQEEEDKM 627

Query: 290 KEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERR 349
           +E  E +  + E  + + + M  +++ MR QEE  R +E    E  + ++ ++R++EE+ 
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE----EKMQGQEEKMREQEEKM 683

Query: 350 RREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM-GQMAM 389
           + +EE  R+QEE MR Q+E   G       QE +M GQ  M
Sbjct: 684 QGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEM 724



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 42/160 (26%), Positives = 81/160 (50%), Gaps = 11/160 (6%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
           + EE + ++  +  Q+    R++  R  +   +E E  MR     + E++  DQ +R  +
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR-----DQEQKMWDQEERMWE 511

Query: 291 E---AREKLEMEMEAARHEHQVMLMRQDLMRRQEELR---RMEELHNQEVQKRKQLELRQ 344
           +    REK E   E  +   Q   MR++   +++E +   + E++  +E  + ++ ++R+
Sbjct: 512 QDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571

Query: 345 EEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           EEE  R +EE  ++QEE MR Q+E         +EQE +M
Sbjct: 572 EEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM 611



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 39/155 (25%), Positives = 81/155 (52%), Gaps = 2/155 (1%)

Query: 231 DDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIK 290
           + EE + E+  +  Q+   + E+  R  +    E E  MR +   +M+KQ+++  ++  K
Sbjct: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEE-KMQKQEENMWEQEEK 428

Query: 291 E-AREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERR 349
           E  +++L  + E    + ++    + +  ++E++R  EE+  QE +  +Q ++R++E++ 
Sbjct: 429 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 488

Query: 350 RREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
             +EE  R QE+ M  Q+E         RE+E RM
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM 523



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 13/107 (12%)

Query: 275 IEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEV 334
           + + + ++ ++  N+KE + KLE   +    + Q   +++++ R++EELR  E+      
Sbjct: 196 LRLAESEKSEIQLNVKELKRKLE-RAKFLLPQVQTNTLQEEMWRQEEELREQEK------ 248

Query: 335 QKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQE 381
                 ++R++EE+  R+EE  R+QE  MR Q+E  +      REQE
Sbjct: 249 ------KIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 45/186 (24%), Positives = 89/186 (47%), Gaps = 26/186 (13%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKA--LIEMEK--- 279
           E M + +++    E+ + + ++  +E+EQ  R  +   +E +  +R K   + E EK   
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 383

Query: 280 -QQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELR--------RMEELH 330
            +++ Q +  I+E  +K+  E E  R + + M  +++ M  QEE          + E+L 
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 443

Query: 331 NQEVQKRKQLELRQEEERRRREEEM------------RRQQEEMMRRQQEGFKGTFPDAR 378
            QE  + ++ ++ ++EE+ R +EEM             R+QE+ M  Q+E  +       
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503

Query: 379 EQEIRM 384
           +QE RM
Sbjct: 504 DQEERM 509



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 56/291 (19%), Positives = 128/291 (43%), Gaps = 46/291 (15%)

Query: 122 AEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAF---SVFGQVERAV 178
           +E ++++L+   L+ K  R +F           LPQ  +N L EE +       + E+ +
Sbjct: 201 SEKSEIQLNVKELKRKLERAKFL----------LPQVQTNTLQEEMWRQEEELREQEKKI 250

Query: 179 VIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPE 238
              +++     + + E  GK   ++   R  E         + +  +  +  + E+ L E
Sbjct: 251 RKQEEKMWRQEERLREQEGKMREQEEKMRRQE---------KRLREQEKELREQEKELRE 301

Query: 239 KLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKA---LIEMEKQQQDQVDRNIKEAREK 295
           +  ++ Q+   + ++   + Q      +    W+    L E EKQ ++Q ++ +++  E+
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ-EQKMRDQEER 360

Query: 296 LEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLE-LRQEEERRRREEE 354
           +  + E  R + + M  ++ +  ++E+++  E +  +E + R++ E +R++EE+ +++EE
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420

Query: 355 MRRQQEEM-------------------MRRQQEGFKGTFPDAREQEIRMGQ 386
              +QEE                    M+ Q+E         R+QE   GQ
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 471



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 39/144 (27%), Positives = 70/144 (48%), Gaps = 10/144 (6%)

Query: 225 EPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQ 284
           E  DQ+ ++E   EK+     Q  K  +Q  R  +      E   R +   +M +Q++  
Sbjct: 483 EQEDQMWEQE---EKM---RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKM 536

Query: 285 VDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQ 344
            +    + +EK   + E    E + M  R+  MR +EE+ R +E   QE +++    +R+
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK----MRE 592

Query: 345 EEERRRREEEMRRQQEEMMRRQQE 368
           +EE+   +EE  ++QEE M  Q+E
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEE 616



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 34/134 (25%), Positives = 70/134 (52%), Gaps = 2/134 (1%)

Query: 249 KEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQ 308
           +ERE+  R  +    E E  M+ +     E+++++   + + E +EKL  E E  + + +
Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL-WEQEKMQEQEE 453

Query: 309 VMLMRQDLMRRQEELRRMEE-LHNQEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQ 367
            +  +++ +R QEE+   E+ +  QE  + ++ ++ ++EE+ R +E+    QEE M  Q 
Sbjct: 454 KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD 513

Query: 368 EGFKGTFPDAREQE 381
           E  +      REQ+
Sbjct: 514 ERLREKEERMREQK 527



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 23/205 (11%)

Query: 231 DDEEGLPEKLVIKNQQFHK--EREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQV--- 285
           + EE + E+     +Q  K  E+E+  +  +   +E E  M W+   E + Q+Q+++   
Sbjct: 578 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM-WEQEEEDKMQEQEEMMWE 636

Query: 286 -DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEE--LHNQEVQKRKQLEL 342
            +  ++E  EK+  + E  R + + M  +++ M+ QEE  R +E  +  QE + R+Q E 
Sbjct: 637 QEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEK 696

Query: 343 R--QEEERRRREEEMRRQQEEM------------MRRQQEGFKGTFPDAREQEIRMGQMA 388
              QEE+   +EE+M  Q+E+M            +R Q+E  +   P+  E+        
Sbjct: 697 MRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPP 756

Query: 389 MGGAMGINNRGAMPPAPVPAGTPAP 413
                 +++ G++ PA   AG  +P
Sbjct: 757 SKVLCNMSHTGSVEPAGGEAGEGSP 781



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 33/144 (22%), Positives = 70/144 (48%), Gaps = 4/144 (2%)

Query: 245 QQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAAR 304
           +Q  K R+Q  +        +E   R +   E  ++Q+    +  K   EK   E E   
Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549

Query: 305 HEHQVMLMRQDLMRRQEELRRMEE--LHNQEVQKRKQLELRQEEERR--RREEEMRRQQE 360
            + +  +  ++ MR +E+  R EE  +  QE + ++Q E  +E+E +   +EE+M+ Q+E
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609

Query: 361 EMMRRQQEGFKGTFPDAREQEIRM 384
           +M  ++++ ++    D  +++  M
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEM 633



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 35/148 (23%), Positives = 78/148 (52%), Gaps = 6/148 (4%)

Query: 225 EPMDQLDDEEGLPE--KLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQ 282
           E  +++ +EE + E  K + + ++  +E+E+  +  +   +E E    W+     E++++
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE-EKEWQQQRLPEQKEK 441

Query: 283 DQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLEL 342
                 ++E  EK+  + E  R + + M  ++  M RQE++R  E+   ++ +K +  E 
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEE-MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500

Query: 343 R--QEEERRRREEEMRRQQEEMMRRQQE 368
           +   +EER   ++E  R++EE MR Q++
Sbjct: 501 KMWDQEERMWEQDERLREKEERMREQKK 528



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 29/103 (28%), Positives = 57/103 (55%), Gaps = 1/103 (0%)

Query: 283 DQVDRNIKEAREKLEM-EMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLE 341
           +++ +   E +EKL + E E +  +  V  +++ L R +  L +++    QE   R++ E
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242

Query: 342 LRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRM 384
           LR++E++ R++EE   +QEE +R Q+   +      R QE R+
Sbjct: 243 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL 285


>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
          Length = 636

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 66/318 (20%), Positives = 140/318 (44%), Gaps = 58/318 (18%)

Query: 76  LFVGNLPPDITEEEMRKLFEKYGKAG---------EVFIHKDKGFGFIRLETRTLAEIAK 126
           L+VG+L PD+TE     L+EK+  AG         ++   +  G+ ++  +    AE A 
Sbjct: 13  LYVGDLHPDVTEA---MLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69

Query: 127 VELDNMPLRGKQLRVRFACHSASLT--------VRNLPQYVSNELLEEAFSVFGQVERAV 178
             ++   ++GK +R+ ++    SL         ++NL + + N+ L + FS FG +    
Sbjct: 70  DTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCK 129

Query: 179 VIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPE 238
           V+ D+ G   G G V F  + AA +A+++ +    LL                       
Sbjct: 130 VVCDENG-SKGYGFVHFETQEAAERAIEKMN--GMLLN--------------------DR 166

Query: 239 KLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREK--- 295
           K+ +   +  KERE     A+ G+   E+       + ++   +D  D  +K+   K   
Sbjct: 167 KVFVGRFKSRKERE-----AELGARAKEFTN-----VYIKNFGEDMDDERLKDLFGKFGP 216

Query: 296 -LEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEE 354
            L +++                 R ++  + ++E++ +E+   KQ+ + + +++  R+ E
Sbjct: 217 ALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKEL-NGKQIYVGRAQKKVERQTE 275

Query: 355 MRRQQEEMMRRQQEGFKG 372
           ++R+ E+M + +   ++G
Sbjct: 276 LKRKFEQMKQDRITRYQG 293



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 47/161 (29%), Positives = 72/161 (44%), Gaps = 30/161 (18%)

Query: 74  SRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD-----KGFGFIRLETRTLAEIAKVE 128
           + +++ N   D+ +E ++ LF K+G A  V +  D     KGFGF+  E    A+ A  E
Sbjct: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDE 250

Query: 129 LDNMPLRGKQLRVRFA------------------------CHSASLTVRNLPQYVSNELL 164
           ++   L GKQ+ V  A                            +L V+NL   + +E L
Sbjct: 251 MNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERL 310

Query: 165 EEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKAL 205
            + FS FG +  A V+++  GR  G G V FS    A KA+
Sbjct: 311 RKEFSPFGTITSAKVMMEG-GRSKGFGFVCFSSPEEATKAV 350



 Score = 32.7 bits (73), Expect = 0.73
 Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 4/77 (5%)

Query: 72  QRSRLFVGNLPPDITEEEMRKLFEKYG--KAGEVFIH--KDKGFGFIRLETRTLAEIAKV 127
           Q   L+V NL   I +E +RK F  +G   + +V +   + KGFGF+   +   A  A  
Sbjct: 292 QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVT 351

Query: 128 ELDNMPLRGKQLRVRFA 144
           E++   +  K L V  A
Sbjct: 352 EMNGRIVATKPLYVALA 368


>gi|115511032 ELAV (embryonic lethal, abnormal vision,
           Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
          Length = 359

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 49/178 (27%), Positives = 87/178 (48%), Gaps = 15/178 (8%)

Query: 43  ANGQQASSQNEGLTIDLKNFRKPGEKTFTQRSR--LFVGNLPPDITEEEMRKLFEKYGKA 100
           +NG   ++   G T    N   P +   T+ S+  L V  LP ++T+EE++ LF   G+ 
Sbjct: 6   SNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEI 65

Query: 101 GEVFIHKDK------GFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFA------CHSA 148
               + +DK      G+GF+       AE A   L+ + L+ K ++V +A         A
Sbjct: 66  ESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDA 125

Query: 149 SLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDD-RGRPSGKGIVEFSGKPAARKAL 205
           +L V  LP+ ++ + LE+ FS +G++  + ++VD   G   G G + F  +  A +A+
Sbjct: 126 NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAI 183



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 13/122 (10%)

Query: 42  PANGQQASSQNEGLTIDLK----NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKY 97
           P + ++A +   GL +  K    ++ +P   +    + L+V  LP  +T++E+ +LF +Y
Sbjct: 90  PKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRD-ANLYVSGLPKTMTQKELEQLFSQY 148

Query: 98  GK--AGEVFIHK----DKGFGFIRLETRTLAEIAKVELDNM--PLRGKQLRVRFACHSAS 149
           G+     + + +     +G GFIR + R  AE A   L+    P   + + V+FA + + 
Sbjct: 149 GRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQ 208

Query: 150 LT 151
            T
Sbjct: 209 KT 210



 Score = 36.2 bits (82), Expect = 0.066
 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 6/74 (8%)

Query: 76  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTLAEIAKVEL 129
           +FV NL PD  E  + ++F  +G    V + +D      KGFGF+ +     A +A   L
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337

Query: 130 DNMPLRGKQLRVRF 143
           +   L  + L+V F
Sbjct: 338 NGYRLGDRVLQVSF 351


>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
           sapiens]
          Length = 370

 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 42/162 (25%), Positives = 73/162 (45%), Gaps = 32/162 (19%)

Query: 74  SRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD-----KGFGFIRLETRTLAEIAKVE 128
           + +++ N   D+ +E ++ +F KYGK   V +  D     KGFGF+  ++   A+ A  E
Sbjct: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEE 249

Query: 129 LDNMPLRG-------------------------KQLRVRFACHSASLTVRNLPQYVSNEL 163
           ++   + G                         K+ R+R  C    L ++NL   + +E 
Sbjct: 250 MNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIR-GCQGVKLYIKNLDDTIDDEK 308

Query: 164 LEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKAL 205
           L   FS FG + R V ++ + G+  G G++ FS    A KA+
Sbjct: 309 LRNEFSSFGSISR-VKVMQEEGQSKGFGLICFSSPEDATKAM 349



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 42/146 (28%), Positives = 74/146 (50%), Gaps = 17/146 (11%)

Query: 76  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD----KGFGFIRLETRTLAEIAKVELDN 131
           L+VG+L  D+TE+ + + F   G    + I +D    +  G+  +    LA+  K  LD 
Sbjct: 12  LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKA-LDT 70

Query: 132 MP---LRGKQLRVRFACHSASLT--------VRNLPQYVSNELLEEAFSVFGQVERAVVI 180
           M    ++GK +R+ ++   A L         ++NL + + N+ L E FS FG++  + V+
Sbjct: 71  MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130

Query: 181 VDDRGRPSGKGIVEFSGKPAARKALD 206
            DD+G   G   V F  + AA +A++
Sbjct: 131 SDDQG-SKGYAFVHFQNQSAADRAIE 155



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 37/149 (24%), Positives = 70/149 (46%), Gaps = 18/149 (12%)

Query: 76  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD----KGFGFIRLETRTLAEIAKVELDN 131
           +F+ NL   I  + + + F  +GK     +  D    KG+ F+  + ++ A+ A  E++ 
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNG 159

Query: 132 MPLRGKQLRV-RF-------------ACHSASLTVRNLPQYVSNELLEEAFSVFGQVERA 177
             L+G ++ V RF             A    ++ ++N    + +E L++ FS +G+    
Sbjct: 160 KLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSV 219

Query: 178 VVIVDDRGRPSGKGIVEFSGKPAARKALD 206
            V+ D  G+  G G V F    AA+KA++
Sbjct: 220 KVMTDSSGKSKGFGFVSFDSHEAAKKAVE 248



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 72  QRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD----KGFGFIRLETRTLAEIAKV 127
           Q  +L++ NL   I +E++R  F  +G    V + ++    KGFG I   +   A  A  
Sbjct: 291 QGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMT 350

Query: 128 ELDNMPLRGKQLRVRFA 144
           E++   L  K L +  A
Sbjct: 351 EMNGRILGSKPLSIALA 367


>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 1 [Homo
            sapiens]
          Length = 1834

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 46/144 (31%), Positives = 72/144 (50%), Gaps = 13/144 (9%)

Query: 278  EKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKR 337
            E+++ D VD  +   R + E     A     V+ + QD  RR+++  ++EE+  +E + R
Sbjct: 1580 EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQ--QLEEMRKREAEDR 1637

Query: 338  KQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAR--EQEIRMGQMAMGGAMGI 395
                 RQEEERRR+EEE  ++  E  RRQ+EG+       R  + +    ++    A G+
Sbjct: 1638 A----RQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGL 1693

Query: 396  NN----RGAMPPAPVPA-GTPAPP 414
                  R   PP+P PA G P PP
Sbjct: 1694 CRPPLPRDYEPPSPSPAPGAPPPP 1717



 Score = 33.1 bits (74), Expect = 0.56
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 10/73 (13%)

Query: 347  ERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPV 406
            ERR+REE  R  ++E  R ++E  +      REQE ++GQM         +    P +P+
Sbjct: 1407 ERRKREEHQRWYEKEKARLEEERER----KRREQERKLGQMR------TQSLNPAPFSPL 1456

Query: 407  PAGTPAPPGPATM 419
             A    P  P+T+
Sbjct: 1457 TAQQMKPEKPSTL 1469


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,580,765
Number of Sequences: 37866
Number of extensions: 1251689
Number of successful extensions: 35547
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 824
Number of HSP's successfully gapped in prelim test: 1029
Number of HSP's that attempted gapping in prelim test: 14926
Number of HSP's gapped (non-prelim): 11826
length of query: 471
length of database: 18,247,518
effective HSP length: 106
effective length of query: 365
effective length of database: 14,233,722
effective search space: 5195308530
effective search space used: 5195308530
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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