Search of human proteins with 223890225

Search of human proteins with 223890225

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
         (301 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223890225 POU class 6 homeobox 1 [Homo sapiens]                    593   e-170
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s...   317   8e-87
gi|170650730 pituitary specific transcription factor 1 isoform b...   141   6e-34
gi|4505955 pituitary specific transcription factor 1 isoform alp...   141   6e-34
gi|4505959 POU domain, class 2, transcription factor 2 [Homo sap...   139   3e-33
gi|42476164 POU class 2 homeobox 1 [Homo sapiens]                     138   5e-33
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa...   135   3e-32
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                      135   3e-32
gi|110624763 POU domain, class 3, transcription factor 4 [Homo s...   132   4e-31
gi|110624765 POU domain, class 3, transcription factor 1 [Homo s...   127   9e-30
gi|148664218 POU transcription factor [Homo sapiens]                  127   2e-29
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...   124   1e-28
gi|42560248 POU domain, class 5, transcription factor 1 isoform ...   115   4e-26
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]     113   2e-25
gi|4505965 POU class 4 homeobox 3 [Homo sapiens]                      112   3e-25
gi|116235491 POU domain, class 5, transcription factor 1 isoform...   112   4e-25
gi|227430410 POU class 5 homeobox 1B [Homo sapiens]                   108   6e-24
gi|23463326 POU domain class 5, transcription factor 2 [Homo sap...    99   6e-21
gi|24234711 paired-like homeodomain transcription factor 2 isofo...    53   3e-07
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  53   3e-07
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]              52   5e-07
gi|21361183 paired-like homeodomain transcription factor 2 isofo...    51   1e-06
gi|24234708 paired-like homeodomain transcription factor 2 isofo...    51   1e-06
gi|148613882 homeobox A4 [Homo sapiens]                                50   2e-06
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]          50   2e-06
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             48   9e-06
gi|24497538 homeobox C4 [Homo sapiens]                                 47   2e-05
gi|24497540 homeobox C4 [Homo sapiens]                                 47   2e-05
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]            47   2e-05
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    47   2e-05

>gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
          Length = 301

 Score =  593 bits (1529), Expect = e-170
 Identities = 301/301 (100%), Positives = 301/301 (100%)

Query: 1   MPGISSQILTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLA 60
           MPGISSQILTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLA
Sbjct: 1   MPGISSQILTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLA 60

Query: 61  SSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCS 120
           SSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCS
Sbjct: 61  SSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCS 120

Query: 121 ETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAY 180
           ETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAY
Sbjct: 121 ETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAY 180

Query: 181 SQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTS 240
           SQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTS
Sbjct: 181 SQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTS 240

Query: 241 FTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQI 300
           FTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQI
Sbjct: 241 FTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQI 300

Query: 301 P 301
           P
Sbjct: 301 P 301


>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
           sapiens]
          Length = 691

 Score =  317 bits (812), Expect = 8e-87
 Identities = 183/345 (53%), Positives = 221/345 (64%), Gaps = 56/345 (16%)

Query: 1   MPGISSQILTNAQGQVIGTLPWVVNSA-SVAAPAPAQSLQVQAVTPQLLLNAQGQVIATL 59
           + G++ Q++TNAQGQ+IGT+P + N   S  A +  Q LQVQ +TPQLL NAQGQ+IAT+
Sbjct: 328 LQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATV 387

Query: 60  ASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPT--------------VPQPAVVIASPAP 105
             + + P   +       SP K   Q  QP+ T                  A +  SP  
Sbjct: 388 IGNQILP--VINTQGITLSPIKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVR 445

Query: 106 AAKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQ 165
            A  S+S+    + S   +V QLVS P T + + DG+NLEEIREFAK FKIRRLSLGLTQ
Sbjct: 446 QASSSSSSS---SSSSALSVGQLVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQ 502

Query: 166 TQVGQALTATEGPAYSQSAICR------------------------------------FE 189
           TQVGQAL+ATEGPAYSQSAICR                                    FE
Sbjct: 503 TQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFE 562

Query: 190 KLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEAL 249
           KLDITPKSAQK+KPVLE+W+ EAE R++ G QNL EF+G EPSKKRKRRTSFTPQA+E L
Sbjct: 563 KLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFIGSEPSKKRKRRTSFTPQALEIL 622

Query: 250 NAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSK 294
           NA+FEKN  P+GQE+TEIA++LNYDREVVRVWFCN+RQ LKNT K
Sbjct: 623 NAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNTIK 667



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 31/101 (30%), Positives = 43/101 (42%), Gaps = 6/101 (5%)

Query: 9   LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPV 68
           LTN QG V       + +  +       SL  Q    QL L  Q Q          PPP 
Sbjct: 146 LTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQ-----QQQQQPPPS 200

Query: 69  AVRKPS-TPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAK 108
             + P   P++P++S+ QP+QPTP    P      PAP ++
Sbjct: 201 TNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQ 241


>gi|170650730 pituitary specific transcription factor 1 isoform beta
           [Homo sapiens]
          Length = 317

 Score =  141 bits (356), Expect = 6e-34
 Identities = 79/165 (47%), Positives = 105/165 (63%), Gaps = 9/165 (5%)

Query: 126 SQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAI 185
           S+LV +P    +D D   + E+ +FA  FK+RR+ LG TQT VG+AL A  G  +SQ+ I
Sbjct: 141 SKLVEEP----IDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTI 196

Query: 186 CRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQA 245
           CRFE L ++ K+A KLK +L KWL EAE   Q G   L     G   +KRKRRT+ +  A
Sbjct: 197 CRFENLQLSFKNACKLKAILSKWLEEAE---QVGA--LYNEKVGANERKRKRRTTISIAA 251

Query: 246 IEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290
            +AL  +F +   P+ QEI  +A+ELN ++EVVRVWFCNRRQ  K
Sbjct: 252 KDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREK 296


>gi|4505955 pituitary specific transcription factor 1 isoform alpha
           [Homo sapiens]
          Length = 291

 Score =  141 bits (356), Expect = 6e-34
 Identities = 79/165 (47%), Positives = 105/165 (63%), Gaps = 9/165 (5%)

Query: 126 SQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAI 185
           S+LV +P    +D D   + E+ +FA  FK+RR+ LG TQT VG+AL A  G  +SQ+ I
Sbjct: 115 SKLVEEP----IDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTI 170

Query: 186 CRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQA 245
           CRFE L ++ K+A KLK +L KWL EAE   Q G   L     G   +KRKRRT+ +  A
Sbjct: 171 CRFENLQLSFKNACKLKAILSKWLEEAE---QVGA--LYNEKVGANERKRKRRTTISIAA 225

Query: 246 IEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290
            +AL  +F +   P+ QEI  +A+ELN ++EVVRVWFCNRRQ  K
Sbjct: 226 KDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREK 270


>gi|4505959 POU domain, class 2, transcription factor 2 [Homo
           sapiens]
          Length = 463

 Score =  139 bits (350), Expect = 3e-33
 Identities = 101/275 (36%), Positives = 138/275 (50%), Gaps = 26/275 (9%)

Query: 30  AAPAPAQSLQVQAVTPQLLLNAQG-----QVIATLASSPLPPPVAVRKPSTPESPAKSEV 84
           AAP P Q  Q      QL+L         Q +  L    L P   ++ P+    P   + 
Sbjct: 75  AAPLPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQS 134

Query: 85  QP-IQPTPTVPQPAVVIASPAPAAKPSASAPI-PITCSETPTVSQLVSKPHTPSLDEDGI 142
           QP + PTP + Q           ++P A  P  P  C E P      S P  PS      
Sbjct: 135 QPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQPPKCLEPP------SHPEEPS------ 182

Query: 143 NLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLK 202
           +LEE+ +FA+ FK RR+ LG TQ  VG A+    G  +SQ+ I RFE L+++ K+  KLK
Sbjct: 183 DLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLK 242

Query: 203 PVLEKWLNEAELRNQEG-----QQNLMEFVG--GEPSKKRKRRTSFTPQAIEALNAYFEK 255
           P+LEKWLN+AE  + +       Q     +G  G P ++RK+RTS       AL   F  
Sbjct: 243 PLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLA 302

Query: 256 NPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290
           N  PT +EI  IA++L+ ++EV+RVWFCNRRQ  K
Sbjct: 303 NQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEK 337


>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
          Length = 743

 Score =  138 bits (348), Expect = 5e-33
 Identities = 84/216 (38%), Positives = 122/216 (56%), Gaps = 13/216 (6%)

Query: 79  PAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPSLD 138
           P +S+   +Q  P++     + + PA   +  A+ PI        T  ++     TPSL+
Sbjct: 229 PQQSQANLLQSQPSI----TLTSQPATPTRTIAATPIQTLPQSQSTPKRI----DTPSLE 280

Query: 139 EDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSA 198
           E   +LEE+ +FAK FK RR+ LG TQ  VG A+    G  +SQ+ I RFE L+++ K+ 
Sbjct: 281 EPS-DLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNM 339

Query: 199 QKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEP----SKKRKRRTSFTPQAIEALNAYFE 254
            KLKP+LEKWLN+AE  + +   +    +        S++RK+RTS       AL   F 
Sbjct: 340 CKLKPLLEKWLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRVALEKSFL 399

Query: 255 KNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290
           +N  PT +EIT IA +LN ++EV+RVWFCNRRQ  K
Sbjct: 400 ENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEK 435



 Score = 28.1 bits (61), Expect = 9.9
 Identities = 30/137 (21%), Positives = 49/137 (35%), Gaps = 8/137 (5%)

Query: 34  PAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTV 93
           P+Q   VQA  PQ  L   G  I  L  +P    + +++         + VQ  Q + + 
Sbjct: 87  PSQQPSVQAAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQAQLLAAAVQ--QHSASQ 144

Query: 94  PQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAKN 153
              A      A AA P    P+         + QL        L +  +NL++       
Sbjct: 145 QHSAAGATISASAATPMTQIPLSQPIQIAQDLQQL------QQLQQQNLNLQQFVLVHPT 198

Query: 154 FKIRRLSLGLTQTQVGQ 170
             ++     ++QT  GQ
Sbjct: 199 TNLQPAQFIISQTPQGQ 215


>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
           sapiens]
          Length = 443

 Score =  135 bits (341), Expect = 3e-32
 Identities = 72/158 (45%), Positives = 97/158 (61%), Gaps = 3/158 (1%)

Query: 133 HTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLD 192
           H P  DED    +++ +FAK FK RR+ LG TQ  VG AL    G  +SQ+ ICRFE L 
Sbjct: 256 HDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ 315

Query: 193 ITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAY 252
           ++ K+  KLKP+L KWL EA+  +  G    ++ +  +  +KRK+RTS       AL ++
Sbjct: 316 LSFKNMCKLKPLLNKWLEEAD--SSSGSPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESH 372

Query: 253 FEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290
           F K P P+ QEIT +A  L  ++EVVRVWFCNRRQ  K
Sbjct: 373 FLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEK 410


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score =  135 bits (341), Expect = 3e-32
 Identities = 73/167 (43%), Positives = 100/167 (59%), Gaps = 3/167 (1%)

Query: 133 HTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLD 192
           H P  DED    +++ +FAK FK RR+ LG TQ  VG AL    G  +SQ+ ICRFE L 
Sbjct: 308 HDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ 367

Query: 193 ITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAY 252
           ++ K+  KLKP+L KWL EA+  +  G    ++ +  +  +KRK+RTS       AL ++
Sbjct: 368 LSFKNMCKLKPLLNKWLEEAD--SSTGSPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESH 424

Query: 253 FEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQ 299
           F K P P+ QEIT +A  L  ++EVVRVWFCNRRQ  K  +   + Q
Sbjct: 425 FLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQ 471


>gi|110624763 POU domain, class 3, transcription factor 4 [Homo
           sapiens]
          Length = 361

 Score =  132 bits (332), Expect = 4e-31
 Identities = 85/221 (38%), Positives = 116/221 (52%), Gaps = 13/221 (5%)

Query: 78  SPAKSEVQPIQPTPTVPQPAVVIA--------SPAPAAKPSASAPIPITCSETPTVSQLV 129
           +P  S     QP     QP   ++        +P PAA  SA +  P+   E P   +L 
Sbjct: 119 APNPSITSSGQPLNVYSQPGFTVSGMLEHGGLTPPPAAA-SAQSLHPVL-REPPDHGELG 176

Query: 130 SKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFE 189
           S       DE+    +E+ +FAK FK RR+ LG TQ  VG AL    G  +SQ+ ICRFE
Sbjct: 177 SHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFE 236

Query: 190 KLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEAL 249
            L ++ K+  KLKP+L KWL EA+  +  G    ++ +  +  +KRK+RTS        L
Sbjct: 237 GLQLSFKNMCKLKPLLNKWLEEAD--SSTGSPTSIDKIAAQ-GRKRKKRTSIEVSVKGVL 293

Query: 250 NAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290
             +F K P P  QEI+ +A  L  ++EVVRVWFCNRRQ  K
Sbjct: 294 ETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEK 334


>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
           sapiens]
          Length = 451

 Score =  127 bits (320), Expect = 9e-30
 Identities = 68/153 (44%), Positives = 94/153 (61%), Gaps = 3/153 (1%)

Query: 138 DEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKS 197
           DED  + +++ +FAK FK RR+ LG TQ  VG AL    G  +SQ+ ICRFE L ++ K+
Sbjct: 246 DEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKN 305

Query: 198 AQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNP 257
             KLKP+L KWL E +  +  G    ++ +  +  +KRK+RTS       AL ++F K P
Sbjct: 306 MCKLKPLLNKWLEETD--SSSGSPTNLDKIAAQ-GRKRKKRTSIEVGVKGALESHFLKCP 362

Query: 258 LPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290
            P+  EIT +A  L  ++EVVRVWFCNRRQ  K
Sbjct: 363 KPSAHEITGLADSLQLEKEVVRVWFCNRRQKEK 395


>gi|148664218 POU transcription factor [Homo sapiens]
          Length = 436

 Score =  127 bits (318), Expect = 2e-29
 Identities = 88/229 (38%), Positives = 121/229 (52%), Gaps = 25/229 (10%)

Query: 79  PAKSEVQP-IQPTPT------VPQPAVVIASPA---PAAKPSASAPIPITCSETPTVSQL 128
           P +  +QP + P P       +PQ    +AS A   P    S+  P        P    L
Sbjct: 117 PGQQGLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHL 176

Query: 129 VSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRF 188
              P +   DE   +LEE+ +FAK FK RR+ LG TQ  VG A+    G  +SQ+ I RF
Sbjct: 177 ---PSSGGADEPS-DLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRF 232

Query: 189 EKLDITPKSAQKLKPVLEKWLNEAE-------LRNQEGQQNLMEFVGGEPSKKRKRRTSF 241
           E L+++ K+  KLKP+LEKWLN+AE       +       +L E  G    +KRK+RTS 
Sbjct: 233 EALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFG----RKRKKRTSI 288

Query: 242 TPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290
                  L   F+ NP P+ +EI+ IA++L+ ++EVVRVWFCNRRQ  K
Sbjct: 289 ETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEK 337


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score =  124 bits (310), Expect = 1e-28
 Identities = 73/201 (36%), Positives = 108/201 (53%), Gaps = 6/201 (2%)

Query: 93  VPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAK 152
           +P P +V A+    A  +A+A      +     + +V      S+ +   +  E+  FA+
Sbjct: 214 LPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAE 273

Query: 153 NFKIRRLSLGLTQTQVGQALTATEGP---AYSQSAICRFEKLDITPKSAQKLKPVLEKWL 209
            FK RR+ LG+TQ  VG AL   + P   + SQS ICRFE L ++  +   LKP+L+ WL
Sbjct: 274 RFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWL 333

Query: 210 NEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAK 269
            EAE   +E       F GGE   K+++RTS       +L AYF   P P+ ++I  IA+
Sbjct: 334 EEAEGAQREKMNKPELFNGGE---KKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAE 390

Query: 270 ELNYDREVVRVWFCNRRQTLK 290
           +L+  + VVRVWFCN+RQ  K
Sbjct: 391 KLDLKKNVVRVWFCNQRQKQK 411


>gi|42560248 POU domain, class 5, transcription factor 1 isoform 1
           [Homo sapiens]
          Length = 360

 Score =  115 bits (289), Expect = 4e-26
 Identities = 74/210 (35%), Positives = 114/210 (54%), Gaps = 14/210 (6%)

Query: 93  VPQPAVVIASPAPAA----KPSASAPIPITCSETPTVSQLVSKP--HTPSLDEDGINLE- 145
           VPQ  +  + P   A    + ++    P  C+ TP   +L  +     P   +D   L+ 
Sbjct: 85  VPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQK 144

Query: 146 EIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVL 205
           E+ +FAK  K +R++LG TQ  VG  L    G  +SQ+ ICRFE L ++ K+  KL+P+L
Sbjct: 145 ELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLL 204

Query: 206 EKWLNEAELRNQEGQQNLMEFVGGEP--SKKRKRRTSFTPQAIEALNAYFEKNPLPTGQE 263
           +KW+ EA     +  +NL E    E     ++++RTS   +    L   F + P PT Q+
Sbjct: 205 QKWVEEA-----DNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQ 259

Query: 264 ITEIAKELNYDREVVRVWFCNRRQTLKNTS 293
           I+ IA++L  +++VVRVWFCNRRQ  K +S
Sbjct: 260 ISHIAQQLGLEKDVVRVWFCNRRQKGKRSS 289


>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
          Length = 409

 Score =  113 bits (283), Expect = 2e-25
 Identities = 70/195 (35%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 99  VIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRR 158
           V+++PA A   +   P+            L S  H   + +   +  ++  FA+ FK RR
Sbjct: 212 VVSTPAHAPHMATMNPMHQAALSMAHAHGLPS--HMGCMSDVDADPRDLEAFAERFKQRR 269

Query: 159 LSLGLTQTQVGQALTATEGP---AYSQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELR 215
           + LG+TQ  VG AL   + P   + SQS ICRFE L ++  +   LKP+L+ WL EAE  
Sbjct: 270 IKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEKS 329

Query: 216 NQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDR 275
           ++E       F G E   K+++RTS       +L AYF   P P+ ++I  IA++L+  +
Sbjct: 330 HREKLTKPELFNGAE---KKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKK 386

Query: 276 EVVRVWFCNRRQTLK 290
            VVRVWFCN+RQ  K
Sbjct: 387 NVVRVWFCNQRQKQK 401


>gi|4505965 POU class 4 homeobox 3 [Homo sapiens]
          Length = 338

 Score =  112 bits (281), Expect = 3e-25
 Identities = 68/173 (39%), Positives = 96/173 (55%), Gaps = 14/173 (8%)

Query: 129 VSKPHTPS--------LDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGP-- 178
           +S PHT +        L +   +  E+  FA+ FK RR+ LG+TQ  VG AL   + P  
Sbjct: 161 MSHPHTVAPHSAMPACLSDVESDPRELEAFAERFKQRRIKLGVTQADVGAALANLKIPGV 220

Query: 179 -AYSQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKR 237
            + SQS ICRFE L ++  +   LKPVL+ WL EAE   +E       F G E   ++++
Sbjct: 221 GSLSQSTICRFESLTLSHNNMIALKPVLQAWLEEAEAAYREKNSKPELFNGSE---RKRK 277

Query: 238 RTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290
           RTS       +L AYF   P P+ ++I  IA++L+  + VVRVWFCN+RQ  K
Sbjct: 278 RTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQK 330


>gi|116235491 POU domain, class 5, transcription factor 1 isoform 2
           [Homo sapiens]
          Length = 265

 Score =  112 bits (280), Expect = 4e-25
 Identities = 61/151 (40%), Positives = 92/151 (60%), Gaps = 7/151 (4%)

Query: 145 EEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPV 204
           +E+ +FAK  K +R++LG TQ  VG  L    G  +SQ+ ICRFE L ++ K+  KL+P+
Sbjct: 49  KELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPL 108

Query: 205 LEKWLNEAELRNQEGQQNLMEFVGGEP--SKKRKRRTSFTPQAIEALNAYFEKNPLPTGQ 262
           L+KW+ EA     +  +NL E    E     ++++RTS   +    L   F + P PT Q
Sbjct: 109 LQKWVEEA-----DNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQ 163

Query: 263 EITEIAKELNYDREVVRVWFCNRRQTLKNTS 293
           +I+ IA++L  +++VVRVWFCNRRQ  K +S
Sbjct: 164 QISHIAQQLGLEKDVVRVWFCNRRQKGKRSS 194


>gi|227430410 POU class 5 homeobox 1B [Homo sapiens]
          Length = 359

 Score =  108 bits (270), Expect = 6e-24
 Identities = 73/210 (34%), Positives = 112/210 (53%), Gaps = 15/210 (7%)

Query: 93  VPQPAVVIASPAPAA----KPSASAPIPITCSETPTVSQLVSKP--HTPSLDEDGINLE- 145
           VPQ  +  + P   A    + +++   P  C+  P   +L  +     P   +D   L+ 
Sbjct: 85  VPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPGAVKLEKEKLEQNPEKSQDIKALQK 144

Query: 146 EIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVL 205
           E+ +FAK  K +R++LG TQ  VG  L    G  +SQ  ICRFE L ++ K+  KL+P+L
Sbjct: 145 ELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSFKNMCKLRPLL 204

Query: 206 EKWLNEAELRNQEGQQNLMEFVGGEP--SKKRKRRTSFTPQAIEALNAYFEKNPLPTGQE 263
           +KW+ EA     +  +NL E    E     ++++RTS   +    L   F + P PT Q 
Sbjct: 205 QKWVEEA-----DNNENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQCPKPTLQ- 258

Query: 264 ITEIAKELNYDREVVRVWFCNRRQTLKNTS 293
           I+ IA++L  +++VVRVWFCNRRQ  K +S
Sbjct: 259 ISHIAQQLGLEKDVVRVWFCNRRQKGKRSS 288


>gi|23463326 POU domain class 5, transcription factor 2 [Homo
           sapiens]
          Length = 328

 Score = 98.6 bits (244), Expect = 6e-21
 Identities = 81/257 (31%), Positives = 121/257 (47%), Gaps = 19/257 (7%)

Query: 32  PAPAQSLQVQAVTPQLLLNAQGQVIATLASSP--LPPPVAVRKPSTP-ESPAKSEVQPIQ 88
           P     L+V  +T      A G+V+   A  P   P P   R P  P     +  + P +
Sbjct: 21  PRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPDVWRIPLGPLPHEFRGWIAPCR 80

Query: 89  PTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIR 148
           P     +    +  P+  A P             P ++ L S P  P  ++    L+E++
Sbjct: 81  PRLGASEAGDWLRRPSEGALPG------------PYIA-LRSIPKLPPPEDISGILKELQ 127

Query: 149 EFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVLEKW 208
           + AK  + +RLSLG +Q  VG A+ A  G   SQ+ ICRFE   ++  +  KL+P+L+KW
Sbjct: 128 QLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLLKKW 187

Query: 209 LNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIA 268
           L E E  N  G    ME +  +  K   RR S   +   +L  +F++ P PT Q+I+ IA
Sbjct: 188 LKEVEAENLLGLCK-MEMILQQSGK--WRRASRERRIGNSLEKFFQRCPKPTPQQISHIA 244

Query: 269 KELNYDREVVRVWFCNR 285
             L   ++VVRVWF NR
Sbjct: 245 GCLQLQKDVVRVWFYNR 261


>gi|24234711 paired-like homeodomain transcription factor 2 isoform
           a [Homo sapiens]
          Length = 271

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 34/78 (43%), Positives = 42/78 (53%), Gaps = 4/78 (5%)

Query: 213 ELRNQEGQQNLMEFVGGE-PSKK---RKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIA 268
           +L   + QQ   E VG E PSKK   R++RT FT Q ++ L A F++N  P      EIA
Sbjct: 14  QLEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIA 73

Query: 269 KELNYDREVVRVWFCNRR 286
              N     VRVWF NRR
Sbjct: 74  VWTNLTEARVRVWFKNRR 91


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 65/288 (22%), Positives = 105/288 (36%), Gaps = 57/288 (19%)

Query: 61   SSP-LPPPVAVRKPSTPESPAKSEVQPIQ------------------PTPTVPQPAVVIA 101
            SSP  PPP     P  P  P  S + P++                  P P  P P     
Sbjct: 1953 SSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPP 2012

Query: 102  SPAPAAKPSASAPIPITCSETPTVS-QLVSKP--------HTPSLDEDGINLEEIRE--- 149
             P P+A P    P+ +     P++  Q V  P          P +D    +L ++ +   
Sbjct: 2013 PPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLTQLCQQQL 2072

Query: 150  -----FAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPV 204
                 F ++ + +R    +T  Q+ + L A      S S     E  + +  S + +K  
Sbjct: 2073 GLDPNFLRHSQFKRPRTRITDDQL-KILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHW 2131

Query: 205  LEKWLNEAELRNQEGQQN-------LMEFVGGEPS-------------KKRKRRTSFTPQ 244
                L +   RN++   N       ++E +  +P               KR  RT FT  
Sbjct: 2132 FRNTLFKERQRNKDSPYNFSNPPITVLEDIRIDPQPTSLEHYKSDASFSKRSSRTRFTDY 2191

Query: 245  AIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNT 292
             +  L  +F+ N  P   EI +++  LN    V+ VWF N RQ  + +
Sbjct: 2192 QLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKS 2239



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 1/59 (1%)

Query: 229  GEPSKKRKR-RTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRR 286
            GE   + KR RT+ TP+ +E L   +  +  PT + +  IA+E+   + VV+VWF N R
Sbjct: 2554 GEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTR 2612



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 216  NQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDR 275
            N  G  N  +    +    ++ RT  +   ++ L A F     PT QE   +  E+   +
Sbjct: 2866 NPFGSSNPFKSKSNDRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPK 2925

Query: 276  EVVRVWFCNRRQTLKNTSKLNV 297
             VV+VWF N R   K   K+N+
Sbjct: 2926 RVVQVWFQNARAKEKK-FKINI 2946



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 8/78 (10%)

Query: 63   PLPPPVAVRKPSTPESPAKSEVQPIQPTPTVP----QPAVVIASPAPAAKPSASAPIPIT 118
            P P P   +    PE PA+   +P Q  P+ P    +PA+ +AS + +  P AS   P  
Sbjct: 2348 PSPKPEPEKTSPKPEYPAE---KPKQSDPSPPSQGTKPALPLASTS-SDPPQASTAQPQP 2403

Query: 119  CSETPTVSQLVSKPHTPS 136
              + P   QL+ +P + S
Sbjct: 2404 QPQPPKQPQLIGRPPSAS 2421



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 9/65 (13%)

Query: 61   SSPLPPPVAVRKPSTP------ESPAKSEVQPIQPTPTVP-QPAVVIASPAPAAKPSASA 113
            S P PP     KP+ P      + P  S  QP QP P  P QP ++   P+ +  P  S+
Sbjct: 2371 SDPSPPSQGT-KPALPLASTSSDPPQASTAQP-QPQPQPPKQPQLIGRPPSASQTPVPSS 2428

Query: 114  PIPIT 118
            P+ I+
Sbjct: 2429 PLQIS 2433


>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
          Length = 1505

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 67/262 (25%), Positives = 103/262 (39%), Gaps = 35/262 (13%)

Query: 61   SSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIA----------SPAPAAKPS 110
            SS   P  +      PESP  S       T  V QP   I           S  PA+   
Sbjct: 1042 SSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPPIEASKDSKPPEPSDPPASDSQ 1101

Query: 111  ASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRL----SLGLTQT 166
             + P+P++     ++ +LV+   +P LD  GI          N   +RL     LGLTQ 
Sbjct: 1102 PTTPLPLSGHSALSIQELVAM--SPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQG 1159

Query: 167  QVGQALTATEGPAYSQSAICR--FEKLDI---TPKSAQKLKPV--LEK--WLNEAELRNQ 217
             V   L A   P +  S   R  F ++ +    P + +KL  +  +EK  ++        
Sbjct: 1160 SVSD-LLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVS 1218

Query: 218  EGQQNLMEFVGGEPS---------KKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIA 268
            + Q      VG E S         + +K R    P+  EAL   +++ P P+ + I ++A
Sbjct: 1219 DSQPCEPPSVGTEYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLA 1278

Query: 269  KELNYDREVVRVWFCNRRQTLK 290
             +LN     V  WF N R  ++
Sbjct: 1279 TQLNLKTSTVINWFHNYRSRIR 1300



 Score = 28.5 bits (62), Expect = 7.6
 Identities = 21/86 (24%), Positives = 29/86 (33%), Gaps = 1/86 (1%)

Query: 51   AQGQVIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPS 110
            A+ + +   A    PPP     P         E  P++    +P PA   A+ APAA   
Sbjct: 1361 AEREEVPRPAEQTEPPPSGTPGPDDARDD-DHEGGPVEGPGPLPSPASATATAAPAAPED 1419

Query: 111  ASAPIPITCSETPTVSQLVSKPHTPS 136
            A+        E P        P   S
Sbjct: 1420 AATSAAAAPGEGPAAPSSAPPPSNSS 1445


>gi|21361183 paired-like homeodomain transcription factor 2 isoform
           c [Homo sapiens]
          Length = 324

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 33/73 (45%), Positives = 40/73 (54%), Gaps = 4/73 (5%)

Query: 218 EGQQNLMEFVGGE-PSKK---RKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNY 273
           + QQ   E VG E PSKK   R++RT FT Q ++ L A F++N  P      EIA   N 
Sbjct: 72  KSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNL 131

Query: 274 DREVVRVWFCNRR 286
               VRVWF NRR
Sbjct: 132 TEARVRVWFKNRR 144


>gi|24234708 paired-like homeodomain transcription factor 2 isoform
           b [Homo sapiens]
          Length = 317

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 33/73 (45%), Positives = 40/73 (54%), Gaps = 4/73 (5%)

Query: 218 EGQQNLMEFVGGE-PSKK---RKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNY 273
           + QQ   E VG E PSKK   R++RT FT Q ++ L A F++N  P      EIA   N 
Sbjct: 65  KSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNL 124

Query: 274 DREVVRVWFCNRR 286
               VRVWF NRR
Sbjct: 125 TEARVRVWFKNRR 137


>gi|148613882 homeobox A4 [Homo sapiens]
          Length = 320

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 38/127 (29%), Positives = 55/127 (43%), Gaps = 9/127 (7%)

Query: 170 QALTATEG-PAYSQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVG 228
           +A  AT G PA   +  C     D +P   +  +PV+  W+ +  +       N     G
Sbjct: 158 EAAPATPGVPAGGSAPACPLLLADKSPLGLKGKEPVVYPWMKKIHVSAVNPSYN-----G 212

Query: 229 GEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQT 288
           GEP   ++ RT++T Q +  L   F  N   T +   EIA  L      V++WF NRR  
Sbjct: 213 GEP---KRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMK 269

Query: 289 LKNTSKL 295
            K   KL
Sbjct: 270 WKKDHKL 276


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 75/314 (23%), Positives = 116/314 (36%), Gaps = 63/314 (20%)

Query: 28   SVAAPAPAQSLQVQAVTPQLLLNAQGQVIAT-------------LASSPLPPPVAVR-KP 73
            S A  APA S    A +  L L A+ + +AT             LA +P   P   + K 
Sbjct: 2388 SQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQ 2447

Query: 74   STPESPAKSEVQPIQPT-------------PTVPQP---AVVIASPAPAAKPSAS--API 115
              P+   + + QP Q T             P++PQP   A     P P + PS S  + +
Sbjct: 2448 GQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHL 2507

Query: 116  PITCSETPTVSQLVSKPHTPSL-----DEDGINLEEIREFAKN----------------F 154
            P+    T T  QL + P  P L     D+  +       + ++                F
Sbjct: 2508 PLKPLHTSTPQQLANLP--PQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQF 2565

Query: 155  KIRRLSLGLTQTQVGQALTATE--GPAYSQSAICRFEKLDITPKSAQKLKPVLEKWLNEA 212
              R L +          L A++    A  Q              +   LK  LE+  + +
Sbjct: 2566 LDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASAS 2625

Query: 213  ELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELN 272
               N  G        G EP + ++ RT+ TP+ +E L   +  +  PT + +  IA E+ 
Sbjct: 2626 PGENDSGTG------GEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVG 2679

Query: 273  YDREVVRVWFCNRR 286
              + VV+VWF N R
Sbjct: 2680 LKKRVVQVWFQNTR 2693



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 54/215 (25%)

Query: 72   KPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPS--ASAPIPITCSETPTVSQLV 129
            +P TPE P         P P  P P +  A P PA+ P+  ASAP PIT   +PT++   
Sbjct: 2033 RPQTPEPPP--------PPPPPPPPPLPAAPPQPASTPAIPASAP-PIT---SPTIA--- 2077

Query: 130  SKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFE 189
              P  PS+         + + +   ++   S  + QT   Q L A   P           
Sbjct: 2078 --PAQPSV--------PLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPP----------- 2116

Query: 190  KLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEAL 249
                      +L PV     + A+L   +    L++       + ++ RT  T   +  L
Sbjct: 2117 ----------QLGPVEPLPADLAQLYQHQLNPTLLQ------QQNKRPRTRITDDQLRVL 2160

Query: 250  NAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCN 284
              YF+ N  P+ ++I E+A +    ++V++ WF N
Sbjct: 2161 RQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRN 2195



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 61/278 (21%), Positives = 93/278 (33%), Gaps = 56/278 (20%)

Query: 30   AAPAPAQSLQVQAVTPQL----LLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKSEVQ 85
            A P PA +  + A  P +    +  AQ  V  T  S P+  P+         SP   +  
Sbjct: 2054 APPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIF--------SPLMMQTM 2105

Query: 86   PIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINL- 144
            P+Q  P    P +    P PA                PT+ Q  +K     + +D + + 
Sbjct: 2106 PLQTLPAQLPPQLGPVEPLPADLAQLYQH-----QLNPTLLQQQNKRPRTRITDDQLRVL 2160

Query: 145  ------------EEIREFAKNFKIRR--LSLGLTQTQVGQALTATEGPA-YSQSAICRFE 189
                        E+I+E A    + +  +      T   +     + P  +S   I   E
Sbjct: 2161 RQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLE 2220

Query: 190  KLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEAL 249
            +L I  +      P  E W                         KR  RT FT   +  L
Sbjct: 2221 ELKIDSRPPSPEPPKQEYW-----------------------GSKRSSRTRFTDYQLRVL 2257

Query: 250  NAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQ 287
              +F+ N  P   E  +++  LN    V+ VWF N RQ
Sbjct: 2258 QDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQ 2295



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 3/66 (4%)

Query: 20   LPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESP 79
            LP   +SAS+++P PAQ+    A+ PQ     Q Q        P PPP A + P TP+ P
Sbjct: 3169 LPNKPSSASLSSPTPAQA--TMAMGPQQPPQQQQQQQQPQVQQP-PPPPAAQPPPTPQLP 3225

Query: 80   AKSEVQ 85
             + + Q
Sbjct: 3226 LQQQQQ 3231



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 228  GGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQ 287
            G  P +KR R T  T   ++ L + F     PT  E   +  ++   + VV+VWF N R 
Sbjct: 2941 GDRPGQKRFR-TQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARA 2999

Query: 288  TLKNTSKLNV 297
              K  SKL++
Sbjct: 3000 KEKK-SKLSM 3008



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 44/165 (26%), Positives = 65/165 (39%), Gaps = 28/165 (16%)

Query: 50   NAQGQVIATLASSPLPPPVAVRKPSTPE----SPAKSEV-----QPIQPTPTVPQPAVVI 100
            N  G    T+ S  LP      KPS+      +PA++ +     QP Q      QP V  
Sbjct: 3150 NLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQ 3209

Query: 101  ASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLS 160
              P PAA+P             P   QL  +      D+D    E+++E  K  K +   
Sbjct: 3210 PPPPPAAQP-------------PPTPQLPLQQQQQRKDKDS---EKVKEKEKAHKGKGEP 3253

Query: 161  LGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVL 205
            L + + + G+A TAT   A + SA     +  + P   Q L+  L
Sbjct: 3254 LPVPKKEKGEAPTAT---AATISAPLPTMEYAVDPAQLQALQAAL 3295



 Score = 28.1 bits (61), Expect = 9.9
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 31   APAPAQSLQVQAVTPQLLLNAQGQVI--ATLASSPLPPPVAVRKPSTPESPAKSEVQPIQ 88
            +P P  +    + +P     +  QV+  A+ A  P  PP++     T  S + S VQP  
Sbjct: 3596 SPPPPSAAAPSSASPHASRKSWPQVVSRASAAKPPSFPPLSSSSTVTSSSCSTSGVQPSM 3655

Query: 89   PT 90
            PT
Sbjct: 3656 PT 3657


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 32/120 (26%), Positives = 46/120 (38%), Gaps = 9/120 (7%)

Query: 26   SASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKS--- 82
            S + A P P +     A  P                 P  P  AV  P  P SPA +   
Sbjct: 1080 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139

Query: 83   EVQPIQPTPTVPQP------AVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPS 136
              +P  P P VP P      AV + +P  +A P+A+ P P   +    V   + +P +P+
Sbjct: 1140 PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPA 1199



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 14/135 (10%)

Query: 26   SASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKSEVQ 85
            SA+VA P P +S    A  P    +A    +      P  P  +V  P+   +  +    
Sbjct: 1158 SAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS 1217

Query: 86   PIQPTPTVPQPAVVIA---------SPAPAA----KPSASAPIPITCSETPTVSQLVSKP 132
            P    PT  +PA + A         SPA A     +P++SA   +T  E  + +  V  P
Sbjct: 1218 PAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP 1277

Query: 133  HTPSLDEDGI-NLEE 146
              P+     + NLEE
Sbjct: 1278 EEPASPAAAVSNLEE 1292



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 33/130 (25%), Positives = 46/130 (35%), Gaps = 12/130 (9%)

Query: 26   SASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKSEVQ 85
            S + A P P +     A  P                 P  P  AV  P  P SPA +   
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1087

Query: 86   PIQPT------PTVPQ---PAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPS 136
            P +PT      PT  +   PA  + +P   A P+A+ P P    E  + +  V  P  P+
Sbjct: 1088 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTP---EEPASPAAAVPTPEEPA 1144

Query: 137  LDEDGINLEE 146
                 +   E
Sbjct: 1145 FPAPAVPTPE 1154



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 33/123 (26%), Positives = 49/123 (39%), Gaps = 14/123 (11%)

Query: 23   VVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKS 82
            V  + +V AP    +  V+  TP+   +    V       P  P  AV  P  P SPA +
Sbjct: 975  VTPATTVHAPEEPDTAAVRVSTPEEPASPAAAV--PTPEEPTSPAAAVPTPEEPTSPAAA 1032

Query: 83   EVQPIQPT------PTVPQ---PAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPH 133
               P +PT      PT  +   PA  + +P     P+A+ P P    E  + +  V  P 
Sbjct: 1033 VPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP---EEPTSPAAAVPTPE 1089

Query: 134  TPS 136
             P+
Sbjct: 1090 EPT 1092



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 29/113 (25%), Positives = 40/113 (35%), Gaps = 6/113 (5%)

Query: 26   SASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKSEVQ 85
            S + A P P +     A  P                 P  P  AV  P  P SPA +   
Sbjct: 1054 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1113

Query: 86   PIQPT------PTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKP 132
            P +P       PT  +PA   A+     +P+  AP   T  E+ + +  V  P
Sbjct: 1114 PEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTP 1166



 Score = 35.4 bits (80), Expect = 0.062
 Identities = 30/118 (25%), Positives = 44/118 (37%), Gaps = 21/118 (17%)

Query: 26   SASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVA-------VRKPSTPES 78
            S + A P P +     A  P            T  ++ +PPP         V  P  P S
Sbjct: 1002 SPAAAVPTPEEPTSPAAAVPT-------PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS 1054

Query: 79   PAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPS 136
            PA +   P +PT     PA  + +P     P+A+ P P    E  + +  V  P  P+
Sbjct: 1055 PAAAVPTPEEPT----SPAAAVPTPEEPTSPAAAVPTP---EEPTSPAAAVPTPEEPT 1105



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 20/133 (15%)

Query: 26   SASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVA-VRKPSTPESPAKSEV 84
            S + A   P +     A  P L         A L    L  P A V  P  P SPA +  
Sbjct: 1230 SLAAAVSNPEEPTSPAAAVPTLE-EPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVS 1288

Query: 85   ---QPIQPTPTVPQPAVV------IASPAPAAKPSASAP---------IPITCSETPTVS 126
               +P  P   VP P V       + +P   A P+A+ P         +P       T S
Sbjct: 1289 NLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDS 1348

Query: 127  QLVSKPHTPSLDE 139
              +S+  TP L+E
Sbjct: 1349 VPISEEGTPVLEE 1361


>gi|24497538 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 8/101 (7%)

Query: 195 PKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFE 254
           P SA   +P++  W+ +  +       N     GGEP   ++ RT++T Q +  L   F 
Sbjct: 125 PSSAASKQPIVYPWMKKIHVSTVNPNYN-----GGEP---KRSRTAYTRQQVLELEKEFH 176

Query: 255 KNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKL 295
            N   T +   EIA  L      +++WF NRR   K   +L
Sbjct: 177 YNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRL 217


>gi|24497540 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 8/101 (7%)

Query: 195 PKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFE 254
           P SA   +P++  W+ +  +       N     GGEP   ++ RT++T Q +  L   F 
Sbjct: 125 PSSAASKQPIVYPWMKKIHVSTVNPNYN-----GGEP---KRSRTAYTRQQVLELEKEFH 176

Query: 255 KNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKL 295
            N   T +   EIA  L      +++WF NRR   K   +L
Sbjct: 177 YNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRL 217


>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 3859

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)

Query: 9   LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPP 67
           +T A   V+   P    + S A P       +  VTP     A G V+  T A SP  P 
Sbjct: 530 VTPADSPVLSVTP----AESPAIPVTPADSPIVPVTP-----ANGPVVPVTSADSPFVPV 580

Query: 68  VAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTV 125
           +    P  P +PA S V P+ P  +      +  SPA    P+ S  +P+T ++ P V
Sbjct: 581 IPADGPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPADSPVVPVTPADGPVV 638



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 1/84 (1%)

Query: 60   ASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITC 119
            A  P+ P  +V  P  P +PA S V P+ P  ++  PA     P  +  P+    +P+T 
Sbjct: 2410 ADGPVVPVTSVDSPVVPVTPADSPVIPVTPADSLVVPATPADDPVVSVTPADGPVVPVTT 2469

Query: 120  SETPTVS-QLVSKPHTPSLDEDGI 142
            ++ P +S      P  P    DG+
Sbjct: 2470 ADIPVISVTSADSPVVPVTPADGL 2493



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 24/83 (28%), Positives = 35/83 (42%)

Query: 58   TLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPI 117
            T A SP+ P  +   P  P +PA   V P+ P      P     SPA    P+ S  +P+
Sbjct: 1960 TPADSPVIPVASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESPAIPVTPTDSPVVPV 2019

Query: 118  TCSETPTVSQLVSKPHTPSLDED 140
            T +++P +      P  P    D
Sbjct: 2020 TSADSPVIPVTADSPFVPVTPAD 2042



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 38/130 (29%), Positives = 51/130 (39%), Gaps = 14/130 (10%)

Query: 9    LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPV 68
            +T A G V+   P     + V    PA  L V       L+     V  T A SP+ P  
Sbjct: 2088 VTPADGPVVPVTP---ADSPVIPVTPADDLIVPVTPADSLI-----VSVTPADSPVVPVT 2139

Query: 69   AVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQL 128
                P    + A S V P+ P  TV  P      P     P+ S  IP+T +++P V   
Sbjct: 2140 PADSPVISVASADSPVVPVTPADTVVVPVTPADGPVIPVTPAESPAIPVTPADSPVV--- 2196

Query: 129  VSKPHTPSLD 138
               P TP+ D
Sbjct: 2197 ---PVTPADD 2203



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 1/77 (1%)

Query: 50  NAQGQVI-ATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAK 108
           +A G VI  T A SP+ P  +   P  P +PA S V P+ P  +   P     SP     
Sbjct: 133 SANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVFPVTPADSPLFPVTPADSPLFPVT 192

Query: 109 PSASAPIPITCSETPTV 125
           P+ SA IP+T ++ P V
Sbjct: 193 PADSAAIPVTPADGPVV 209



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 8/124 (6%)

Query: 20  LPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIA-TLASSPLPPPVAVRKPSTPES 78
           +P +     V    PA S  V  VTP     A   V++ TLA SP  P      P  P +
Sbjct: 578 VPVIPADGPVVPVTPADS-PVVPVTP-----ADSPVLSVTLADSPAVPVTPADSPVVPVT 631

Query: 79  PAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVS-QLVSKPHTPSL 137
           PA   V P+    +   P      P  +  P+ S  IP+T +++P V      +P  P  
Sbjct: 632 PADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVIPVT 691

Query: 138 DEDG 141
             DG
Sbjct: 692 TADG 695



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 21/69 (30%), Positives = 31/69 (44%)

Query: 55   VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
            V  T A  P+ P      P+ P +PA S V P+ P      P     SP     P++   
Sbjct: 2166 VPVTPADGPVIPVTPAESPAIPVTPADSPVVPVTPADDPVVPVTPADSPIVPVPPASDPV 2225

Query: 115  IPITCSETP 123
            +P+T ++TP
Sbjct: 2226 VPVTPADTP 2234



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 22/72 (30%), Positives = 35/72 (48%)

Query: 55   VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
            V  T A+SP+ P      P  P +PA S V P+ P   +  P     S   +  P+ S  
Sbjct: 2076 VSVTPANSPVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIVSVTPADSPV 2135

Query: 115  IPITCSETPTVS 126
            +P+T +++P +S
Sbjct: 2136 VPVTPADSPVIS 2147



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 34   PAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPT 92
            PA SL V +VTP     A   V+  T A SP+    +   P  P +PA + V P+ P   
Sbjct: 2120 PADSLIV-SVTP-----ADSPVVPVTPADSPVISVASADSPVVPVTPADTVVVPVTPADG 2173

Query: 93   VPQPAVVIASPAPAAKPSASAPIPITCSETPTV 125
               P     SPA    P+ S  +P+T ++ P V
Sbjct: 2174 PVIPVTPAESPAIPVTPADSPVVPVTPADDPVV 2206



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 38/143 (26%), Positives = 55/143 (38%), Gaps = 19/143 (13%)

Query: 9   LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPV 68
           +T+A G V    P       V    PA S  +   T   L+     V  T A SP+    
Sbjct: 490 VTSADGPVA---PVSSADGPVVPVTPADSPFIPVTTADDLI-----VPVTPADSPVLSVT 541

Query: 69  AVRKPSTPESPAKSEVQPIQPT--PTVPQ--------PAVVIASPAPAAKPSASAPIPIT 118
               P+ P +PA S + P+ P   P VP         P +    P     P+ S  +P+T
Sbjct: 542 PAESPAIPVTPADSPIVPVTPANGPVVPVTSADSPFVPVIPADGPVVPVTPADSPVVPVT 601

Query: 119 CSETPTVS-QLVSKPHTPSLDED 140
            +++P +S  L   P  P    D
Sbjct: 602 PADSPVLSVTLADSPAVPVTPAD 624



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 22/71 (30%), Positives = 32/71 (45%)

Query: 55   VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
            V  T A SP+ P      P  P + A S + P+ P   V  P +    P     P+ S  
Sbjct: 1947 VSVTPADSPVFPVTPADSPVIPVASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESPA 2006

Query: 115  IPITCSETPTV 125
            IP+T +++P V
Sbjct: 2007 IPVTPTDSPVV 2017



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 32/114 (28%), Positives = 43/114 (37%), Gaps = 9/114 (7%)

Query: 12   AQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVR 71
            A G VI   P    + S A P       V  VT     +A   VI   A SP  P     
Sbjct: 1992 ADGPVIPVTP----AESPAIPVTPTDSPVVPVT-----SADSPVIPVTADSPFVPVTPAD 2042

Query: 72   KPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTV 125
             P  P +P    V P+ P      P  ++  P  +  P+ S   P+T ++ P V
Sbjct: 2043 SPVIPVTPPDDLVVPVTPIDCPVVPVTLVDCPVVSVTPANSPVDPVTPADGPVV 2096



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 1/78 (1%)

Query: 50  NAQGQVI-ATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAK 108
           +A G V+  T A SP+ P      P  P +PA S + P+ P  +   P      P     
Sbjct: 153 SADGPVVPVTPADSPVFPVTPADSPLFPVTPADSPLFPVTPADSAAIPVTPADGPVVHVT 212

Query: 109 PSASAPIPITCSETPTVS 126
           P+    +P+T +++P V+
Sbjct: 213 PANGTVVPVTPADSPVVT 230



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 36/131 (27%), Positives = 51/131 (38%), Gaps = 22/131 (16%)

Query: 2    PGISSQILTNAQGQVI------GTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQV 55
            P  S  IL    G V+      G +  V  + S   P  +    V  VTP     A G V
Sbjct: 1272 PADSPVILVTPVGPVVSVTTADGPVVLVSTADSPVIPVTSADSPVVPVTP-----ADGPV 1326

Query: 56   I-ATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
            +  T A SP  P      P  P +PA S +  + P            SPA    P+ S  
Sbjct: 1327 VPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPA----------ESPAIPVTPADSPV 1376

Query: 115  IPITCSETPTV 125
            +P+T +++P +
Sbjct: 1377 VPVTSADSPLI 1387



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 6/104 (5%)

Query: 23  VVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPPVAVRKPSTPESPAK 81
           V ++     P  +  + +  VTP       G V+  T A  P+ P  +   P  P +PA 
Sbjct: 460 VTSADGPVVPVTSADIPLVPVTPP-----DGPVVPVTSADGPVAPVSSADGPVVPVTPAD 514

Query: 82  SEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTV 125
           S   P+     +  P     SP  +  P+ S  IP+T +++P V
Sbjct: 515 SPFIPVTTADDLIVPVTPADSPVLSVTPAESPAIPVTPADSPIV 558



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 1/89 (1%)

Query: 55   VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
            V  T A SP+ P      P  P SPA   V P+ P  +   P     SP     P+    
Sbjct: 2585 VPVTSADSPVFPVTPADSPVFPVSPADDLVVPVTPGDSPVVPVSPADSPVVLVTPADGPV 2644

Query: 115  IPITCSETPTVS-QLVSKPHTPSLDEDGI 142
            +P+T +  P V       P  P +  DG+
Sbjct: 2645 VPVTPANGPVVPVTSADSPFVPVIPADGL 2673



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 21/69 (30%), Positives = 30/69 (43%)

Query: 58  TLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPI 117
           TLA SP+ P      P  P  PA   V P+ P  +   P      P  +   + S  +P+
Sbjct: 341 TLADSPVVPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTPADGPVVSVASADSPFVPV 400

Query: 118 TCSETPTVS 126
           T ++ P VS
Sbjct: 401 TPADDPIVS 409



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 35/134 (26%), Positives = 44/134 (32%), Gaps = 19/134 (14%)

Query: 9    LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPV 68
            +T A G VI   P    + S A P       V  VTP              A  P+ P  
Sbjct: 2168 VTPADGPVIPVTP----AESPAIPVTPADSPVVPVTP--------------ADDPVVPVT 2209

Query: 69   AVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQL 128
                P  P  PA   V P+ P  T   P      P      + S  +P+T  ++P V   
Sbjct: 2210 PADSPIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSADSPLVPVTPGDSPVVPVT 2269

Query: 129  -VSKPHTPSLDEDG 141
                P  P    DG
Sbjct: 2270 PADSPVFPVTSADG 2283



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 29/92 (31%), Positives = 40/92 (43%), Gaps = 7/92 (7%)

Query: 35   AQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTV 93
            A SL V  VTP     A G V+  T A  P+ P  +   P  P +PA S V P+      
Sbjct: 1743 ADSLPVP-VTP-----ADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPVTTADDP 1796

Query: 94   PQPAVVIASPAPAAKPSASAPIPITCSETPTV 125
              P     SP     P+    +P+T +++P V
Sbjct: 1797 TVPVTPADSPVVPVPPANGPIVPVTSADSPFV 1828



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 7/118 (5%)

Query: 31   APAPAQSLQVQAVTP-----QLLLNAQGQVIA-TLASSPLPPPVAVRKPSTPESPAKSEV 84
            AP  +    V  VTP       +  A G V+  T A  P+ P      P    +PA   V
Sbjct: 919  APVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPADSPVVSVTPADGPV 978

Query: 85   QPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVS-QLVSKPHTPSLDEDG 141
             P+    +   P      P  +  P+ S  IP+T +++P V      +P +P    DG
Sbjct: 979  VPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVSPVTTADG 1036



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 27/105 (25%), Positives = 42/105 (40%), Gaps = 7/105 (6%)

Query: 20   LPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPPVAVRKPSTPES 78
            +P     + + +  PA+S  +  VTP     A   V+  T A SPL P         P +
Sbjct: 1347 VPVTPADSPIVSVTPAESPAIP-VTP-----ADSPVVPVTSADSPLIPLTTAGSRVVPVT 1400

Query: 79   PAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETP 123
            P    + P+ P  T   P      P     P+    +P+T ++TP
Sbjct: 1401 PTGDPIVPVTPADTPGSPVTSADGPVVPVTPAGDPIVPVTPADTP 1445



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 10/71 (14%)

Query: 55   VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
            V  TLA  P+ P  +V  P  P +PA   V P+ P          +  P  +  P+  + 
Sbjct: 1606 VPVTLADGPVVPVTSVDIPVVPVTPANGPVAPVTP----------VDDPVVSVNPADGSV 1655

Query: 115  IPITCSETPTV 125
            +P+T ++ P V
Sbjct: 1656 VPVTSADCPVV 1666



 Score = 37.4 bits (85), Expect = 0.016
 Identities = 21/72 (29%), Positives = 30/72 (41%)

Query: 55   VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
            V  T + SP+ P      P  P +PA   V P+    +   P     SP     P+ S  
Sbjct: 2385 VSVTTSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPADSPVIPVTPADSLV 2444

Query: 115  IPITCSETPTVS 126
            +P T ++ P VS
Sbjct: 2445 VPATPADDPVVS 2456



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 21/72 (29%), Positives = 31/72 (43%)

Query: 55  VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
           V  T A  P+ P      P    + A S V P+ P  +   PA+    P     P+ S  
Sbjct: 318 VSVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPFVPAIPADGPVVPVTPADSPV 377

Query: 115 IPITCSETPTVS 126
           +P+T ++ P VS
Sbjct: 378 VPVTPADGPVVS 389



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 9/80 (11%)

Query: 55   VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQP--------TPTVPQPAVVIASPAPA 106
            V  T+A SP+ P      P  P + A S V P+ P        TP  P  +V  A     
Sbjct: 1238 VSVTIADSPVIPVTPADSPVVPVTSADSPVVPVTPADSPVILVTPVGPVVSVTTADGPVV 1297

Query: 107  AKPSASAP-IPITCSETPTV 125
               +A +P IP+T +++P V
Sbjct: 1298 LVSTADSPVIPVTSADSPVV 1317



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 33/126 (26%), Positives = 51/126 (40%), Gaps = 11/126 (8%)

Query: 18   GTLPWVVNSASVAAPA-PAQSLQVQAVTPQLLL----NAQGQVIATLASSPLPPPVAVRK 72
            G++  V ++ S   P  PA  L V   +  +L+       G  +  LA  P+        
Sbjct: 2333 GSVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVVLVSPTDGIPVPDLADDPVVSVTTSDS 2392

Query: 73   PSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKP 132
            P  P +P  S V P+ P      P   + SP     P+ S  IP+T +++  V      P
Sbjct: 2393 PVIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPADSPVIPVTPADSLVV------P 2446

Query: 133  HTPSLD 138
             TP+ D
Sbjct: 2447 ATPADD 2452



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 34/119 (28%), Positives = 47/119 (39%), Gaps = 10/119 (8%)

Query: 9    LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPP 67
            +T A   VI   P    + S+  PA      V +VTP     A G V+  T A  P+   
Sbjct: 2427 VTPADSPVIPVTP----ADSLVVPATPADDPVVSVTP-----ADGPVVPVTTADIPVISV 2477

Query: 68   VAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVS 126
             +   P  P +PA   V P+    +V  PA     P     P+ S  +  T  + P VS
Sbjct: 2478 TSADSPVVPVTPADGLVVPVTSADSVVVPATPADCPLVPVDPADSPIVLFTPYDNPVVS 2536



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 16/84 (19%)

Query: 55  VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIAS------------ 102
           V  T A SP  P +    P  P +PA S V P+ P      P V +AS            
Sbjct: 348 VPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTP---ADGPVVSVASADSPFVPVTPAD 404

Query: 103 -PAPAAKPSASAPIPITCSETPTV 125
            P  +  P+ S  +P+T +++P +
Sbjct: 405 DPIVSVTPADSPVVPVTSADSPLI 428



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 29/106 (27%), Positives = 43/106 (40%), Gaps = 10/106 (9%)

Query: 23   VVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKS 82
            V  + S   P  +    V  VT      A G+++   A+    P V V    TP SP  S
Sbjct: 1011 VTQADSPVVPVTSADRPVSPVT-----TADGRIVPVTAAGD--PIVPVTPADTPGSPVTS 1063

Query: 83   EVQPIQPTPTVPQPAVVIASPAPAAKP--SASAPI-PITCSETPTV 125
               P+ P  +   P V +  P     P  SA  P+ P++ ++ P V
Sbjct: 1064 ADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVV 1109



 Score = 35.0 bits (79), Expect = 0.081
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 20/91 (21%)

Query: 55   VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPT--PTVP---------------QPA 97
            V+ T A  P+ P  +V  P  P +PA + V P+ P   P VP                P 
Sbjct: 1887 VLVTPADGPVVPVTSVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSADSPI 1946

Query: 98   VVIA---SPAPAAKPSASAPIPITCSETPTV 125
            V +    SP     P+ S  IP+  +++P V
Sbjct: 1947 VSVTPADSPVFPVTPADSPVIPVASADSPLV 1977



 Score = 35.0 bits (79), Expect = 0.081
 Identities = 34/121 (28%), Positives = 51/121 (42%), Gaps = 16/121 (13%)

Query: 9    LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPP 67
            + +A G V+     V ++ S   P       V  VTP     A   V   T A  P+ P 
Sbjct: 2238 VASADGPVVP----VTSADSPLVPVTPGDSPVVPVTP-----ADSPVFPVTSADGPVFPV 2288

Query: 68   VAVRKPSTPESPAKSEVQPIQP--TPTVP-QPAVVIASPAPAAKPSASAPIPITCSETPT 124
                 P  P +PA   + P+ P  +P VP  PA +   P P   P+  + +P+T + +P 
Sbjct: 2289 TLADDPVFPVTPADDPIFPVSPADSPVVPVTPANIPVVPVP---PANGSVVPVTSAGSPF 2345

Query: 125  V 125
            V
Sbjct: 2346 V 2346



 Score = 35.0 bits (79), Expect = 0.081
 Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 8/115 (6%)

Query: 9    LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPV 68
            +T A G V+     V ++ SV  PA      +  V P         V+ T   +P+    
Sbjct: 2487 VTPADGLVVP----VTSADSVVVPATPADCPLVPVDPA----DSPIVLFTPYDNPVVSVT 2538

Query: 69   AVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETP 123
            +   P  P +PA S V P+ P      P      P     P+ S  +P+T +++P
Sbjct: 2539 SDDSPVFPVTPADSSVVPVTPAGVPVVPVTPGDGPVVPVTPADSLVVPVTSADSP 2593



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 4/83 (4%)

Query: 58  TLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPI 117
           T A +P+ P  +   P  P +PA S V P+        P     SP     P+ S   P+
Sbjct: 122 TPADNPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVFPVTPADSPLFPV 181

Query: 118 TCSETP----TVSQLVSKPHTPS 136
           T +++P    T +   + P TP+
Sbjct: 182 TPADSPLFPVTPADSAAIPVTPA 204



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 29/106 (27%), Positives = 43/106 (40%), Gaps = 10/106 (9%)

Query: 23  VVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKS 82
           V  + S   P  +    V  VT      A G+++   A+    P V V    TP SP  S
Sbjct: 670 VTQADSPVVPVTSADRPVIPVT-----TADGRIVPVTAAGD--PIVPVTPADTPGSPVTS 722

Query: 83  EVQPIQPTPTVPQPAVVIASPAPAAKP--SASAPI-PITCSETPTV 125
              P+ P  +   P V +  P     P  SA  P+ P++ ++ P V
Sbjct: 723 ADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVV 768



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 9/113 (7%)

Query: 9   LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPP 67
           +++A G V+     V ++    AP  +    V  VTP    +  G  +  T A SP  P 
Sbjct: 760 VSSADGPVVP----VTSADGPVAPVSSADGPVVPVTPA---DTNGPAVPVTSADSPFVPV 812

Query: 68  VAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCS 120
           +    P  P +PA   + P+ P  +   P +   SP     P A  P+ +  S
Sbjct: 813 IPADSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIP-ADGPVVVDSS 864



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 7/99 (7%)

Query: 32  PAPAQSLQVQAVTPQLL--LNAQGQVIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQP 89
           PA +  + V +    L+    A G+V+   A+    P V V    TP SP  S   P+ P
Sbjct: 412 PADSPVVPVTSADSPLIPVTTADGRVVPVTAAGD--PIVPVTPADTPGSPVTSADGPVVP 469

Query: 90  TPTVPQPAVVIASPAPAAKP--SASAPI-PITCSETPTV 125
             +   P V +  P     P  SA  P+ P++ ++ P V
Sbjct: 470 VTSADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPVV 508



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 12/117 (10%)

Query: 12   AQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPPVAV 70
            A G V+   P       V    PA  L V  VTP     A   ++  T A SP+    + 
Sbjct: 1651 ADGSVV---PVTSADCPVVPVTPADGLVVP-VTP-----ADSPIVPVTPADSPVVLVTSA 1701

Query: 71   RKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSA--SAPIPITCSETPTV 125
              P  P +PA S V P+    T    + V ++  P    ++  S P+P+T ++ P V
Sbjct: 1702 DSPVIPVTPADSPVVPVTSADTDSPGSPVTSADGPVVPVTSADSLPVPVTPADGPVV 1758



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 3/85 (3%)

Query: 60   ASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITC 119
            A   + P  +   P  P +PA   V P+ P  +   P     SP      + S  IP+T 
Sbjct: 1651 ADGSVVPVTSADCPVVPVTPADGLVVPVTPADSPIVPVTPADSPVVLVTSADSPVIPVTP 1710

Query: 120  SETPTV---SQLVSKPHTPSLDEDG 141
            +++P V   S     P +P    DG
Sbjct: 1711 ADSPVVPVTSADTDSPGSPVTSADG 1735



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 23/86 (26%), Positives = 35/86 (40%), Gaps = 6/86 (6%)

Query: 53   GQVIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSAS 112
            G ++  LA  P+        P  P +PA S V  + P      P   + +P     P+ +
Sbjct: 1855 GILVPDLADDPVVSVTIADSPVIPVTPADSPVVLVTPADGPVVPVTSVDNPVVPVTPADN 1914

Query: 113  APIPITCSETPTVSQLVSKPHTPSLD 138
              IP+T  + P V      P TP+ D
Sbjct: 1915 PVIPVTPVDDPVV------PVTPADD 1934



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 1/77 (1%)

Query: 50   NAQGQVI-ATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAK 108
            +A G V+  T A SP  P      P  P +PA S V  +    +   P     SP     
Sbjct: 1123 SADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPVIPVP 1182

Query: 109  PSASAPIPITCSETPTV 125
            P+    +P++ +++P V
Sbjct: 1183 PANGPVVPVSSADSPFV 1199



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 29/118 (24%), Positives = 43/118 (36%), Gaps = 10/118 (8%)

Query: 9    LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPP 67
            +T+A G V+   P    +     P          VT     +A G V+  T    PL P 
Sbjct: 1419 VTSADGPVVPVTP----AGDPIVPVTPADTPGSPVT-----SADGPVVPVTTPDGPLVPV 1469

Query: 68   VAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTV 125
                 P  P + A   V P+ P  +   P      P     P+ S  +P+T ++ P V
Sbjct: 1470 SPPDGPVVPVTSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVPVTPADIPVV 1527



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 7/89 (7%)

Query: 51   AQGQVI-ATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIA---SPAPA 106
            A G V+  T A  P+ P         P +PA S + P+ P  +   P V++    SP   
Sbjct: 1651 ADGSVVPVTSADCPVVPVTPADGLVVPVTPADSPIVPVTPADS---PVVLVTSADSPVIP 1707

Query: 107  AKPSASAPIPITCSETPTVSQLVSKPHTP 135
              P+ S  +P+T ++T +    V+    P
Sbjct: 1708 VTPADSPVVPVTSADTDSPGSPVTSADGP 1736



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 38/128 (29%), Positives = 50/128 (39%), Gaps = 20/128 (15%)

Query: 9   LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPP 67
           +T+A G VI   P    + S   P  +    V  VTP     A   V   T A SPL P 
Sbjct: 131 VTSANGPVIPVTP----ADSPVFPVASADGPVVPVTP-----ADSPVFPVTPADSPLFPV 181

Query: 68  VAVRKPSTPESPAKSEVQPIQPT--PTV---PQPAVVIA-----SPAPAAKPSASAPIPI 117
                P  P +PA S   P+ P   P V   P    V+      SP      + S  +P+
Sbjct: 182 TPADSPLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSPVVPV 241

Query: 118 TCSETPTV 125
           T ++ P V
Sbjct: 242 TPADDPIV 249



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 38/138 (27%), Positives = 52/138 (37%), Gaps = 17/138 (12%)

Query: 9    LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATL-ASSPLPPP 67
            +T A G V+   P+      +    PA S  V +VTP     A G V+    A SP  P 
Sbjct: 941  VTAADGPVV---PFTPADDPIVPVTPADS-PVVSVTP-----ADGPVVPVASADSPFVPV 991

Query: 68   VAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP---IPITCSETPT 124
                 P    +PA+S   P  P      P V + S      P  +A    +P+T +  P 
Sbjct: 992  TPADDPIVSVTPAES---PAIPVTQADSPVVPVTSADRPVSPVTTADGRIVPVTAAGDPI 1048

Query: 125  VSQL-VSKPHTPSLDEDG 141
            V       P +P    DG
Sbjct: 1049 VPVTPADTPGSPVTSADG 1066



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 7/80 (8%)

Query: 50   NAQGQVI-ATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIA---SPAP 105
            +A G V+  T A  P+ P  +   P  P +PA S   P  P  T   P V +    SP  
Sbjct: 1103 SADGPVVPVTSADGPVAPVSSADGPVVPVTPADS---PFIPVTTADDPIVPVTPADSPVL 1159

Query: 106  AAKPSASAPIPITCSETPTV 125
            +   + S  +P+T +++P +
Sbjct: 1160 SVTLADSPVVPVTPADSPVI 1179



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 34/131 (25%), Positives = 50/131 (38%), Gaps = 8/131 (6%)

Query: 9    LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQV-QAVTPQLLLNAQGQVIATLASSPLPPP 67
            +T A   ++   P   + A    PA +  + V  A +P + L   G  +  +  +   P 
Sbjct: 1349 VTPADSPIVSVTP-AESPAIPVTPADSPVVPVTSADSPLIPLTTAGSRVVPVTPTG-DPI 1406

Query: 68   VAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP---IPITCSETPT 124
            V V    TP SP  S   P+ P      P V +        P  SA    +P+T  + P 
Sbjct: 1407 VPVTPADTPGSPVTSADGPVVPVTPAGDPIVPVTPADTPGSPVTSADGPVVPVTTPDGPL 1466

Query: 125  VSQLVSKPHTP 135
            V   VS P  P
Sbjct: 1467 VP--VSPPDGP 1475



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 18/68 (26%), Positives = 27/68 (39%)

Query: 58   TLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPI 117
            T A  P+ P  +      P +PA   V P+        P      P     P+ S  +P+
Sbjct: 1731 TSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPV 1790

Query: 118  TCSETPTV 125
            T ++ PTV
Sbjct: 1791 TTADDPTV 1798



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 32/118 (27%), Positives = 46/118 (38%), Gaps = 9/118 (7%)

Query: 9    LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPV 68
            +T+A   VI   P   +S  V    PA S  +    P  L+     V  T    P+ P  
Sbjct: 2019 VTSADSPVI---PVTADSPFVPV-TPADSPVIPVTPPDDLV-----VPVTPIDCPVVPVT 2069

Query: 69   AVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVS 126
             V  P    +PA S V P+ P      P     SP     P+    +P+T +++  VS
Sbjct: 2070 LVDCPVVSVTPANSPVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIVS 2127



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 7/99 (7%)

Query: 23  VVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPPVAVRKPSTPESPAK 81
           V  + S A P       V  VTP     A G V+  T A SP+    +   P  P +PA 
Sbjct: 191 VTPADSAAIPVTPADGPVVHVTP-----ANGTVVPVTPADSPVVTVASTDSPVVPVTPAD 245

Query: 82  SEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCS 120
             + P+ P  +   P +   SP     P A  P+ +  S
Sbjct: 246 DPIVPVTPADSSFVPVISADSPFVPVIP-ADGPVVVDSS 283



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 21/84 (25%), Positives = 31/84 (36%), Gaps = 6/84 (7%)

Query: 55  VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
           ++   A   + P      P  P +P    V P+ PT     P      P     P+ S  
Sbjct: 879 LVPAFADETVVPLNPADSPVIPVTPPDDLVVPVTPTDCPVAPVTSADCPVVPVTPADSPA 938

Query: 115 IPITCSETPTVSQLVSKPHTPSLD 138
            P+T ++ P V      P TP+ D
Sbjct: 939 DPVTAADGPVV------PFTPADD 956



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 30/114 (26%), Positives = 45/114 (39%), Gaps = 16/114 (14%)

Query: 23   VVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKS 82
            V ++ S   P      +V  VTP         V  T A +P  P  +   P  P +PA  
Sbjct: 1379 VTSADSPLIPLTTAGSRVVPVTP----TGDPIVPVTPADTPGSPVTSADGPVVPVTPAGD 1434

Query: 83   EVQPIQP--TPTVP-----QPAVVIASP----APAAKPSASAPIPITCSETPTV 125
             + P+ P  TP  P      P V + +P     P + P     +P+T ++ P V
Sbjct: 1435 PIVPVTPADTPGSPVTSADGPVVPVTTPDGPLVPVSPPDGPV-VPVTSADGPVV 1487



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 19/74 (25%), Positives = 28/74 (37%)

Query: 53   GQVIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSAS 112
            G ++  LA  P+        P  P +PA S V P+        P   +  P     P+  
Sbjct: 1574 GVLVPDLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPVTSVDIPVVPVTPANG 1633

Query: 113  APIPITCSETPTVS 126
               P+T  + P VS
Sbjct: 1634 PVAPVTPVDDPVVS 1647



 Score = 31.6 bits (70), Expect = 0.90
 Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 10/76 (13%)

Query: 58  TLASSPLPPPVAVRKPSTPESPAKSEVQPIQPT--PTVP-----QPAVVIAS---PAPAA 107
           T A SP+ P  +   P  P +PA + V P+     P +P      P   +AS   P    
Sbjct: 102 TPADSPVIPVTSADDPVVPITPADNPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPV 161

Query: 108 KPSASAPIPITCSETP 123
            P+ S   P+T +++P
Sbjct: 162 TPADSPVFPVTPADSP 177



 Score = 31.6 bits (70), Expect = 0.90
 Identities = 31/117 (26%), Positives = 44/117 (37%), Gaps = 17/117 (14%)

Query: 20  LPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATL-ASSPLPPPVAVRKPSTPES 78
           +P +     V    PA S  V  VTP     A G V++   A SP  P      P    +
Sbjct: 358 VPAIPADGPVVPVTPADS-PVVPVTP-----ADGPVVSVASADSPFVPVTPADDPIVSVT 411

Query: 79  PAKSEVQPIQP--TPTVPQ--------PAVVIASPAPAAKPSASAPIPITCSETPTV 125
           PA S V P+    +P +P         P      P     P+ +   P+T ++ P V
Sbjct: 412 PADSPVVPVTSADSPLIPVTTADGRVVPVTAAGDPIVPVTPADTPGSPVTSADGPVV 468



 Score = 31.6 bits (70), Expect = 0.90
 Identities = 28/113 (24%), Positives = 44/113 (38%), Gaps = 7/113 (6%)

Query: 21  PWVVNSAS---VAAPAPAQSLQVQAVTPQLLLN---AQGQVIATLASSPLPPPVAVRK-P 73
           P VV+S++   V    P   + V A   + ++    A   VI       L  PV     P
Sbjct: 858 PVVVDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIPVTPPDDLVVPVTPTDCP 917

Query: 74  STPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVS 126
             P + A   V P+ P  +   P      P     P+    +P+T +++P VS
Sbjct: 918 VAPVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPADSPVVS 970



 Score = 31.6 bits (70), Expect = 0.90
 Identities = 36/130 (27%), Positives = 54/130 (41%), Gaps = 22/130 (16%)

Query: 9    LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVI-ATLASSPLPPP 67
            +T A G V+   P     + +    PA S  V      L+ +A   VI  T A SP+ P 
Sbjct: 1668 VTPADGLVVPVTP---ADSPIVPVTPADSPVV------LVTSADSPVIPVTPADSPVVPV 1718

Query: 68   VAVR--KPSTPESPAKSEVQPIQ-----PTPTVPQ--PAVVIASPAPAAKPSASAP---I 115
             +     P +P + A   V P+      P P  P   P V + S      P +SA    +
Sbjct: 1719 TSADTDSPGSPVTSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVSSADGPVV 1778

Query: 116  PITCSETPTV 125
            P+T +++P V
Sbjct: 1779 PVTPADSPVV 1788



 Score = 31.6 bits (70), Expect = 0.90
 Identities = 19/77 (24%), Positives = 31/77 (40%), Gaps = 1/77 (1%)

Query: 50   NAQGQVIATLASSPLPPPVAVRK-PSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAK 108
            +A G V+   ++  LP PV     P  P + A   V P+        P     SP     
Sbjct: 1732 SADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPVT 1791

Query: 109  PSASAPIPITCSETPTV 125
             +    +P+T +++P V
Sbjct: 1792 TADDPTVPVTPADSPVV 1808



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 22/88 (25%), Positives = 29/88 (32%), Gaps = 1/88 (1%)

Query: 55   VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
            V  T A SP  P      P  P + A   V P+        P      P     P+ +  
Sbjct: 999  VSVTPAESPAIPVTQADSPVVPVTSADRPVSPVTTADGRIVPVTAAGDPIVPVTPADTPG 1058

Query: 115  IPITCSETPTVS-QLVSKPHTPSLDEDG 141
             P+T ++ P V       P  P    DG
Sbjct: 1059 SPVTSADGPVVPVTSADSPFVPVTPPDG 1086



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 7/84 (8%)

Query: 63   PLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIA---SPAPAAKPSASAPIPITC 119
            P+ P  +   P  P +PA S   P  P  T   P V +    SP     P+    +P+T 
Sbjct: 1475 PVVPVTSADGPVVPVTPADS---PFIPVTTADDPIVPVTPADSPVVPVTPADIPVVPVTP 1531

Query: 120  SETPTVSQLVSK-PHTPSLDEDGI 142
            +  P +    +  P  P +  DG+
Sbjct: 1532 ANGPVIHVTSADCPFVPVIPADGL 1555



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 18/71 (25%), Positives = 27/71 (38%)

Query: 55   VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
            V  T+A SP+ P      P    +PA   V P+        P     +P     P     
Sbjct: 1867 VSVTIADSPVIPVTPADSPVVLVTPADGPVVPVTSVDNPVVPVTPADNPVIPVTPVDDPV 1926

Query: 115  IPITCSETPTV 125
            +P+T ++ P V
Sbjct: 1927 VPVTPADDPIV 1937



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 31/143 (21%), Positives = 50/143 (34%), Gaps = 8/143 (5%)

Query: 1   MPGISSQILTNAQGQVIGTLPWVVNSASVAAPA-PAQSLQVQAVTPQLLLNAQGQVIATL 59
           +PG    +      Q  G++  V  + S   P  PA  L V   +  +L      V+   
Sbjct: 20  LPGSPVVLPITVVVQTDGSVVPVTRAGSPFVPVIPADGLVVLDSSTDVL------VVPVF 73

Query: 60  ASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITC 119
            +  +  P     P  P +PA   V P+ P  +   P      P     P+ +  +P+T 
Sbjct: 74  PADGILVPDFADNPVVPVTPADDLVFPVTPADSPVIPVTSADDPVVPITPADNPVVPVTS 133

Query: 120 SETPTVSQL-VSKPHTPSLDEDG 141
           +  P +       P  P    DG
Sbjct: 134 ANGPVIPVTPADSPVFPVASADG 156



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 29/116 (25%), Positives = 39/116 (33%), Gaps = 7/116 (6%)

Query: 28  SVAAPAPAQSLQVQAVTPQLLLNAQGQVIATL-ASSPLPPPVAVRKPSTPESPAKSEVQP 86
           S A P       V  VTP     A G V+    A SP  P      P    +PA+S   P
Sbjct: 615 SPAVPVTPADSPVVPVTP-----ADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIP 669

Query: 87  IQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQL-VSKPHTPSLDEDG 141
           +    +   P      P      +    +P+T +  P V       P +P    DG
Sbjct: 670 VTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADG 725



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 3/48 (6%)

Query: 50   NAQGQVI-ATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPT--PTVP 94
            +A G V+  T A SP  P      P  P +PA S V P+ P   P VP
Sbjct: 1481 SADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVPVTPADIPVVP 1528



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 14/96 (14%)

Query: 50   NAQGQVIA-TLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAK 108
            ++ G V+A +L    L P         P+SPA   V    P PT   P         A  
Sbjct: 3220 SSDGPVVADSLDDDGLVPVTPADDSVVPDSPANGLV---VPDPTTDGPV--------APD 3268

Query: 109  PSASAP-IPITCSETPTVS-QLVSKPHTPSLDEDGI 142
            PS   P +P+T ++ PTVS  L   P       DG+
Sbjct: 3269 PSVDGPVVPVTPADAPTVSVTLADCPDVTVTPPDGL 3304



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 22/88 (25%), Positives = 29/88 (32%), Gaps = 1/88 (1%)

Query: 55  VIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAP 114
           V  T A SP  P      P  P + A   V P+        P      P     P+ +  
Sbjct: 658 VSVTPAESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPIVPVTPADTPG 717

Query: 115 IPITCSETPTVS-QLVSKPHTPSLDEDG 141
            P+T ++ P V       P  P    DG
Sbjct: 718 SPVTSADGPVVPVTSADSPFVPVTPPDG 745



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 15/98 (15%)

Query: 9    LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIA-TLASSPLPPP 67
            +++A G V+   P    + S   P       +  VTP     A   V++ TLA SP+ P 
Sbjct: 1121 VSSADGPVVPVTP----ADSPFIPVTTADDPIVPVTP-----ADSPVLSVTLADSPVVPV 1171

Query: 68   VAVRKPSTPESPAKSEVQPIQP-----TPTVPQPAVVI 100
                 P  P  PA   V P+        P +P   +V+
Sbjct: 1172 TPADSPVIPVPPANGPVVPVSSADSPFVPVIPADGLVV 1209



 Score = 29.3 bits (64), Expect = 4.4
 Identities = 29/113 (25%), Positives = 45/113 (39%), Gaps = 18/113 (15%)

Query: 32  PAPAQSLQVQAVTP-----QLLLNAQGQVI-ATLASSPLPPPVAVRKPSTPESPAKSEVQ 85
           P  A    +  VTP       + +A G V+  T A SP  P   V  P  P  P  S   
Sbjct: 699 PVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVP---VTPPDGPVVPVTSADG 755

Query: 86  PIQPTPTVPQPAVVIASPAPAAKPSASAPI-PITCSETPTVSQLVSKPHTPSL 137
           P+ P  +   P V + S        A  P+ P++ ++ P V    +  + P++
Sbjct: 756 PVAPVSSADGPVVPVTS--------ADGPVAPVSSADGPVVPVTPADTNGPAV 800



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 18/101 (17%)

Query: 32   PAPAQSLQVQAVTP-----QLLLNAQGQVI-ATLASSPLPPPVAVRKPSTPESPAKSEVQ 85
            P  A    +  VTP       + +A G V+  T A SP  P   V  P  P  P  S   
Sbjct: 1040 PVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVP---VTPPDGPVVPVTSADG 1096

Query: 86   PIQPTPTVPQPAVVIASPAPAAKPSASAPI-PITCSETPTV 125
            P+ P  +   P V + S        A  P+ P++ ++ P V
Sbjct: 1097 PVAPVSSADGPVVPVTS--------ADGPVAPVSSADGPVV 1129



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 28/116 (24%), Positives = 40/116 (34%), Gaps = 20/116 (17%)

Query: 23   VVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKS 82
            V  + S   P P  S  V  VTP              A +P  P  +   P  P + A S
Sbjct: 2208 VTPADSPIVPVPPASDPVVPVTP--------------ADTPGSPVASADGPVVPVTSADS 2253

Query: 83   EVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPSLD 138
             + P+ P  +   P     SP      +     P+T ++ P        P TP+ D
Sbjct: 2254 PLVPVTPGDSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVF------PVTPADD 2303


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 22/65 (33%), Positives = 36/65 (55%)

Query: 231 PSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290
           P +KR+RRT+FT   ++ L  +F+++  P       +A  LN   + V+VWF NRR   K
Sbjct: 136 PERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWK 195

Query: 291 NTSKL 295
              ++
Sbjct: 196 RNQRV 200


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.127    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,515,242
Number of Sequences: 37866
Number of extensions: 723470
Number of successful extensions: 10216
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 524
Number of HSP's successfully gapped in prelim test: 719
Number of HSP's that attempted gapping in prelim test: 5076
Number of HSP's gapped (non-prelim): 4114
length of query: 301
length of database: 18,247,518
effective HSP length: 102
effective length of query: 199
effective length of database: 14,385,186
effective search space: 2862652014
effective search space used: 2862652014
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.