Guide to the Human Genome
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Search of human proteins with 223718708

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo
sapiens]
         (249 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s...   516   e-147
gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s...   344   5e-95
gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]    318   2e-87
gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]    295   3e-80
gi|27436964 potassium voltage-gated channel, shaker-related subf...    61   8e-10
gi|27436962 potassium voltage-gated channel, shaker-related subf...    61   8e-10
gi|27436966 potassium voltage-gated channel, shaker-related subf...    61   8e-10
gi|4504825 potassium voltage-gated channel, shaker-related subfa...    59   3e-09
gi|27436969 potassium voltage-gated channel, shaker-related subf...    59   3e-09
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]      57   1e-08
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]     55   7e-08
gi|27436971 potassium voltage-gated channel, shaker-related subf...    54   1e-07
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]     54   2e-07
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]      54   2e-07
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]     51   1e-06
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]          45   6e-05
gi|169208912 PREDICTED: hypothetical protein [Homo sapiens]            36   0.036
gi|169208667 PREDICTED: hypothetical protein [Homo sapiens]            36   0.036
gi|169208084 PREDICTED: hypothetical protein [Homo sapiens]            36   0.036
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]     35   0.061
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]      35   0.061
gi|148529025 pleckstrin homology domain containing, family G (wi...    35   0.061
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    34   0.10 
gi|126090909 engrailed homeobox 1 [Homo sapiens]                       34   0.14 
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         33   0.30 
gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens]     33   0.30 
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    32   0.40 
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      32   0.40 
gi|239742114 PREDICTED: similar to hCG2023245 [Homo sapiens]           32   0.40 
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    32   0.40 

>gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo
           sapiens]
          Length = 249

 Score =  516 bits (1330), Expect = e-147
 Identities = 249/249 (100%), Positives = 249/249 (100%)

Query: 1   MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGG 60
           MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGG
Sbjct: 1   MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGG 60

Query: 61  LGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAP 120
           LGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCP VDLFYLHAPDHSAP
Sbjct: 61  LGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAP 120

Query: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQLLEGAPLRGHC 180
           VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQLLEGAPLRGHC
Sbjct: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQLLEGAPLRGHC 180

Query: 181 PGGEGPAGRVWRQRSQHDLGRPPVDVPPLTAAGCPRGRGHPGHVQPGAAGAELGSGRGRA 240
           PGGEGPAGRVWRQRSQHDLGRPPVDVPPLTAAGCPRGRGHPGHVQPGAAGAELGSGRGRA
Sbjct: 181 PGGEGPAGRVWRQRSQHDLGRPPVDVPPLTAAGCPRGRGHPGHVQPGAAGAELGSGRGRA 240

Query: 241 PGAGCRGRL 249
           PGAGCRGRL
Sbjct: 241 PGAGCRGRL 249


>gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo
           sapiens]
          Length = 331

 Score =  344 bits (882), Expect = 5e-95
 Identities = 171/177 (96%), Positives = 172/177 (97%)

Query: 1   MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGG 60
           MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGG
Sbjct: 1   MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGG 60

Query: 61  LGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAP 120
           LGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCP VDLFYLHAPDHSAP
Sbjct: 61  LGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAP 120

Query: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQLLEGAPLR 177
           VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ +  A  R
Sbjct: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTR 177


>gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]
          Length = 331

 Score =  318 bits (816), Expect = 2e-87
 Identities = 158/177 (89%), Positives = 163/177 (92%)

Query: 1   MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGG 60
           MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAF+YS+GQSETILGG
Sbjct: 1   MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG 60

Query: 61  LGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAP 120
           LGLR+G SDCRVKI TKA P  GNSLKPDS+R QLETSLKRLQCP VDLFYLH PDHS P
Sbjct: 61  LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP 120

Query: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQLLEGAPLR 177
           VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ +  A  R
Sbjct: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITR 177


>gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]
          Length = 359

 Score =  295 bits (755), Expect = 3e-80
 Identities = 145/181 (80%), Positives = 155/181 (85%), Gaps = 5/181 (2%)

Query: 2   SRQLSRARP-----ATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSET 56
           +R L+ +RP     A+VLG MEMGRRMDAP SAA  RAFLERGHTE+DTAF+YSDGQSET
Sbjct: 25  ARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSET 84

Query: 57  ILGGLGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPD 116
           ILGGLGL +G  DCRVKIATKANPW G SLKPDSVRSQLETSLKRLQCP VDLFYLHAPD
Sbjct: 85  ILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPD 144

Query: 117 HSAPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQLLEGAPL 176
           H  PVEETL AC +LHQEGKFVELGLSNYA+WEVAEICTLCKSNGWILPTVYQ +  A  
Sbjct: 145 HGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATT 204

Query: 177 R 177
           R
Sbjct: 205 R 205


>gi|27436964 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 3 [Homo sapiens]
          Length = 401

 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 7/155 (4%)

Query: 20  GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKAN 79
           G+  D      +T A+ E G    DTA +Y+ G++E ILG +  + G     + I TK  
Sbjct: 96  GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 154

Query: 80  PWIGNS-----LKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQE 134
            W G +     L    +   L+ SL+RLQ   VD+ + + PD + P+EE +RA   +  +
Sbjct: 155 -WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQ 213

Query: 135 GKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169
           G  +  G S ++A E+ E  ++ +    I P   Q
Sbjct: 214 GMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQ 248


>gi|27436962 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 2 [Homo sapiens]
          Length = 408

 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 7/155 (4%)

Query: 20  GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKAN 79
           G+  D      +T A+ E G    DTA +Y+ G++E ILG +  + G     + I TK  
Sbjct: 103 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 161

Query: 80  PWIGNS-----LKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQE 134
            W G +     L    +   L+ SL+RLQ   VD+ + + PD + P+EE +RA   +  +
Sbjct: 162 -WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQ 220

Query: 135 GKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169
           G  +  G S ++A E+ E  ++ +    I P   Q
Sbjct: 221 GMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQ 255


>gi|27436966 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 1 [Homo sapiens]
          Length = 419

 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 7/155 (4%)

Query: 20  GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKAN 79
           G+  D      +T A+ E G    DTA +Y+ G++E ILG +  + G     + I TK  
Sbjct: 114 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 172

Query: 80  PWIGNS-----LKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQE 134
            W G +     L    +   L+ SL+RLQ   VD+ + + PD + P+EE +RA   +  +
Sbjct: 173 -WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQ 231

Query: 135 GKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169
           G  +  G S ++A E+ E  ++ +    I P   Q
Sbjct: 232 GMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQ 266


>gi|4504825 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 1 [Homo sapiens]
          Length = 367

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 41/144 (28%), Positives = 73/144 (50%), Gaps = 7/144 (4%)

Query: 20  GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKAN 79
           G+  D      +T A+ + G    DTA +Y+ G++E +LG +  + G     + I TK  
Sbjct: 62  GQITDEMAEQLMTLAY-DNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIF 120

Query: 80  PWIGNS-----LKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQE 134
            W G +     L    +   L+ SL+RLQ   VD+ + + PD + P+EET+RA   +  +
Sbjct: 121 -WGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQ 179

Query: 135 GKFVELGLSNYAAWEVAEICTLCK 158
           G  +  G S +++ E+ E  ++ +
Sbjct: 180 GMAMYWGTSRWSSMEIMEAYSVAR 203


>gi|27436969 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 2 [Homo sapiens]
          Length = 353

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 41/144 (28%), Positives = 73/144 (50%), Gaps = 7/144 (4%)

Query: 20  GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKAN 79
           G+  D      +T A+ + G    DTA +Y+ G++E +LG +  + G     + I TK  
Sbjct: 48  GQITDEMAEQLMTLAY-DNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIF 106

Query: 80  PWIGNS-----LKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQE 134
            W G +     L    +   L+ SL+RLQ   VD+ + + PD + P+EET+RA   +  +
Sbjct: 107 -WGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQ 165

Query: 135 GKFVELGLSNYAAWEVAEICTLCK 158
           G  +  G S +++ E+ E  ++ +
Sbjct: 166 GMAMYWGTSRWSSMEIMEAYSVAR 189


>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
          Length = 323

 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 50/146 (34%), Positives = 69/146 (47%), Gaps = 17/146 (11%)

Query: 24  DAPTSAAV--TRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78
           + P S A+  T+  +E G   ID+A LY++ +      GL +R   +D  VK   I   +
Sbjct: 28  EVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83

Query: 79  NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138
             W  NS +P+ VR  LE SLK LQ   VDL+ +H P    P EE +       + GK +
Sbjct: 84  KLWC-NSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKIL 138

Query: 139 ELGLSNYAAWEVAEICT---LCKSNG 161
              +   A WE  E C    L KS G
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIG 164


>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
          Length = 323

 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 47/137 (34%), Positives = 65/137 (47%), Gaps = 15/137 (10%)

Query: 31  VTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKANPWIGNSLK 87
           VT+  +E G   ID+A+LY++ +      GL +R   +D  VK   I   +  W     +
Sbjct: 37  VTKLAIEAGFRHIDSAYLYNNEEQV----GLAIRSKIADGSVKREDIFYTSKLWC-TFFQ 91

Query: 88  PDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFVELGLSNYAA 147
           P  V+  LE+SLK+LQ   VDL+ LH P    P E  L       + GK +   +   A 
Sbjct: 92  PQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL----PKDENGKVIFDTVDLSAT 147

Query: 148 WEVAEICT---LCKSNG 161
           WEV E C    L KS G
Sbjct: 148 WEVMEKCKDAGLAKSIG 164


>gi|27436971 potassium voltage-gated channel, shaker-related
           subfamily, beta member 3 [Homo sapiens]
          Length = 404

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 42/154 (27%), Positives = 66/154 (42%), Gaps = 4/154 (2%)

Query: 20  GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGL----GLRMGSSDCRVKIA 75
           G ++   T+  V     E G    DTA +Y+ G++E  LG +    G R  S     KI 
Sbjct: 102 GSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIF 161

Query: 76  TKANPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEG 135
                     L    +   L  SL+RLQ   VD+ + +  D + P+EE +RA   +  +G
Sbjct: 162 WGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQG 221

Query: 136 KFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169
             +  G S + A E+ E  ++ +    I P   Q
Sbjct: 222 LALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQ 255


>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 48/146 (32%), Positives = 68/146 (46%), Gaps = 17/146 (11%)

Query: 24  DAPTSAAV--TRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78
           + P S A+   +  +E G   ID+A +Y++ +      GL +R   +D  VK   I   +
Sbjct: 28  EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83

Query: 79  NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138
             W  NS +P+ VR  LE SLK LQ   VDL+ +H P    P EE +       + GK +
Sbjct: 84  KLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKIL 138

Query: 139 ELGLSNYAAWEVAEICT---LCKSNG 161
              +   A WE  E C    L KS G
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIG 164


>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 48/146 (32%), Positives = 68/146 (46%), Gaps = 17/146 (11%)

Query: 24  DAPTSAAV--TRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78
           + P S A+   +  +E G   ID+A +Y++ +      GL +R   +D  VK   I   +
Sbjct: 28  EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83

Query: 79  NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138
             W  NS +P+ VR  LE SLK LQ   VDL+ +H P    P EE +       + GK +
Sbjct: 84  KLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKIL 138

Query: 139 ELGLSNYAAWEVAEICT---LCKSNG 161
              +   A WE  E C    L KS G
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIG 164


>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
          Length = 323

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 47/146 (32%), Positives = 66/146 (45%), Gaps = 17/146 (11%)

Query: 24  DAPTSAA--VTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78
           + P S A  VT+  +E G   ID+A LY++ +      GL +R   +D  VK   I   +
Sbjct: 28  EVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83

Query: 79  NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138
             W     +P+ VR  LE SLK+ Q   VDL+ +H+P    P EE         + GK +
Sbjct: 84  KLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE----LSPTDENGKVI 138

Query: 139 ELGLSNYAAWEVAEICT---LCKSNG 161
              +     WE  E C    L KS G
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIG 164


>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
          Length = 139

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 10/97 (10%)

Query: 24  DAPTSAAV--TRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78
           + P S A+   +  +E G   ID+A +Y++ +      GL +R   +D  VK   I   +
Sbjct: 28  EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83

Query: 79  NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAP 115
             W  NS +P+ VR  LE SLK LQ   VDL+ +H P
Sbjct: 84  KLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119


>gi|169208912 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score = 35.8 bits (81), Expect = 0.036
 Identities = 20/46 (43%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 200 GRPPVDVPPLTAAGCPRGRGHPGHVQPGAAGAELGSGRGRAPGAGC 245
           GR P   PP    G P      G   PG AG E G   G APG GC
Sbjct: 32  GRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPG-GC 76


>gi|169208667 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score = 35.8 bits (81), Expect = 0.036
 Identities = 20/46 (43%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 200 GRPPVDVPPLTAAGCPRGRGHPGHVQPGAAGAELGSGRGRAPGAGC 245
           GR P   PP    G P      G   PG AG E G   G APG GC
Sbjct: 32  GRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPG-GC 76


>gi|169208084 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score = 35.8 bits (81), Expect = 0.036
 Identities = 20/46 (43%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 200 GRPPVDVPPLTAAGCPRGRGHPGHVQPGAAGAELGSGRGRAPGAGC 245
           GR P   PP    G P      G   PG AG E G   G APG GC
Sbjct: 32  GRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPG-GC 76


>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score = 35.0 bits (79), Expect = 0.061
 Identities = 47/206 (22%), Positives = 77/206 (37%), Gaps = 34/206 (16%)

Query: 30  AVTRAFLERGHTEIDTAFLYSDGQS--ETILGGLGLRMGSSDCRVKIATKANPWIGNSLK 87
           A  +  L  G+  ID A +Y +     E +   +G   G +  R ++   +  W      
Sbjct: 31  AAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG--PGKAVPREELFVTSKLW-NTKHH 87

Query: 88  PDSVRSQLETSLKRLQCPUVDLFYLHAP------DHSAP-------------VEETLRAC 128
           P+ V   L  +L  LQ   +DL+ +H P      D+  P              +ET +A 
Sbjct: 88  PEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147

Query: 129 HQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPT-VYQLLEGAPLRGHCPGGE--- 184
             L  +G    LGLSN+ + ++ +I ++      +L    +  L    L  HC       
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207

Query: 185 ------GPAGRVWRQRSQHDLGRPPV 204
                 G + R WR   +  L   PV
Sbjct: 208 TAYSPLGSSDRAWRDPDEPVLLEEPV 233


>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score = 35.0 bits (79), Expect = 0.061
 Identities = 47/206 (22%), Positives = 77/206 (37%), Gaps = 34/206 (16%)

Query: 30  AVTRAFLERGHTEIDTAFLYSDGQS--ETILGGLGLRMGSSDCRVKIATKANPWIGNSLK 87
           A  +  L  G+  ID A +Y +     E +   +G   G +  R ++   +  W      
Sbjct: 31  AAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG--PGKAVPREELFVTSKLW-NTKHH 87

Query: 88  PDSVRSQLETSLKRLQCPUVDLFYLHAP------DHSAP-------------VEETLRAC 128
           P+ V   L  +L  LQ   +DL+ +H P      D+  P              +ET +A 
Sbjct: 88  PEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147

Query: 129 HQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPT-VYQLLEGAPLRGHCPGGE--- 184
             L  +G    LGLSN+ + ++ +I ++      +L    +  L    L  HC       
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207

Query: 185 ------GPAGRVWRQRSQHDLGRPPV 204
                 G + R WR   +  L   PV
Sbjct: 208 TAYSPLGSSDRAWRDPDEPVLLEEPV 233


>gi|148529025 pleckstrin homology domain containing, family G (with
            RhoGef domain) member 4B [Homo sapiens]
          Length = 1271

 Score = 35.0 bits (79), Expect = 0.061
 Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 5/100 (5%)

Query: 10   PATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEI-DTAFLYSDGQSETILGGLGLRMGSS 68
            P +++   E   R     S++   A  +R H+ I D++   S  QS +ILG LGL + SS
Sbjct: 1158 PDSIVKGTESQMRGSTAVSSSDHAAPFKRPHSTISDSSTSSSSSQSSSILGSLGLLVSSS 1217

Query: 69   DCRVKIATKA-NPW---IGNSLKPDSVRSQLETSLKRLQC 104
                 + + A +PW   I   ++ D    +LET  +   C
Sbjct: 1218 PAHPGLWSPAHSPWSSDIRACVEEDEPEPELETGTQAAVC 1257


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 34.3 bits (77), Expect = 0.10
 Identities = 28/79 (35%), Positives = 29/79 (36%), Gaps = 9/79 (11%)

Query: 173 GAPLRGH-CPGGEGPA-GRVWRQRSQHDLGRPPVDVPPLTAA-------GCPRGRGHPGH 223
           G P+RG    GG GP  G   R R       PP   PP   A       G P GRG PG 
Sbjct: 684 GDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG 743

Query: 224 VQPGAAGAELGSGRGRAPG 242
              G  G     G G   G
Sbjct: 744 GMVGGGGHRPHEGPGGGMG 762


>gi|126090909 engrailed homeobox 1 [Homo sapiens]
          Length = 392

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 31/82 (37%), Positives = 33/82 (40%), Gaps = 13/82 (15%)

Query: 169 QLLEGAPLRGHCPGGEGPAGRVWRQRSQHDLGRPPVDVPPLTAAGC-------PRGRGHP 221
           QLL  A  RG    G G  GRV R R Q   GR PV      A G            G P
Sbjct: 125 QLLVAAAARG----GAGGGGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCGPP 180

Query: 222 GHVQPGAAGAELGSGRGRAPGA 243
              QP AAGA  G+ +   P A
Sbjct: 181 DGSQPAAAGA--GASKAGNPAA 200


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 32.7 bits (73), Expect = 0.30
 Identities = 31/84 (36%), Positives = 37/84 (44%), Gaps = 19/84 (22%)

Query: 180 CPGGEGPAG-------RVWRQRSQHDLGRPPVDVPP-----LTAAGCPRGRGHPGHVQPG 227
           CPG EGPAG       +  + R  H  G P V  PP       A G P   G PG+  PG
Sbjct: 790 CPGAEGPAGIPGFLGLKGPKGREGH-AGFPGVPGPPGHSCERGAPGIPGQPGLPGY--PG 846

Query: 228 AAGAELGSGR----GRAPGAGCRG 247
           + GA  G G+    G    AG +G
Sbjct: 847 SPGAPGGKGQPGDVGPPGPAGMKG 870


>gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens]
          Length = 471

 Score = 32.7 bits (73), Expect = 0.30
 Identities = 23/56 (41%), Positives = 27/56 (48%), Gaps = 7/56 (12%)

Query: 197 HDLGRPPVDVPPLTAAGCPRGRGHP----GHVQPGAAGAELGSGR-GRAPGAGCRG 247
           +D  +PP+  PPL  AGC R  G P    G   P       G GR GR+ G G RG
Sbjct: 3   YDSQQPPL--PPLPYAGCRRASGFPALGRGGTVPVGVWGGAGQGREGRSWGEGPRG 56


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 32.3 bits (72), Expect = 0.40
 Identities = 24/63 (38%), Positives = 26/63 (41%), Gaps = 3/63 (4%)

Query: 185 GPAGRVWRQRSQHDLGRPPVDVPPLTAAGCPRGRGHPGHVQPGAAGAELGSGRGRAPGAG 244
           GP GR+  + S    GRP       TA G P G    G  Q   AG E G  RG      
Sbjct: 70  GPRGRLRSRDSS--CGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPE-GPARGPKVSFS 126

Query: 245 CRG 247
           CRG
Sbjct: 127 CRG 129


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 32.3 bits (72), Expect = 0.40
 Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 8/66 (12%)

Query: 181 PGGEGPAGRVWRQRSQHDLGRPPVDVPPLTAAGCPRGRGHPG----HVQPGAAGAELGSG 236
           PGG GPAG    Q  + + G P        AAG P  RG PG    +  PG  G     G
Sbjct: 845 PGGSGPAGPPGPQGVKGERGSPGGP----GAAGFPGARGLPGPPGSNGNPGPPGPSGSPG 900

Query: 237 RGRAPG 242
           +   PG
Sbjct: 901 KDGPPG 906



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 6/80 (7%)

Query: 173 GAPLRGHCPGGEGPAGRVWRQRSQHDLGRPPVDVPPLTAAGCPRGRGHPGHVQP-GAAGA 231
           GAP     PG  G AG      ++   G+P    PP T AG P   G  G V P G+ G+
Sbjct: 303 GAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGT-AGFPGSPGAKGEVGPAGSPGS 361

Query: 232 ELGSGRGRAPG----AGCRG 247
               G+   PG    AG +G
Sbjct: 362 NGAPGQRGEPGPQGHAGAQG 381



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 21/81 (25%)

Query: 172  EGAPLRGHCPGGEGPAGRVWRQRSQHDLGRPPVDVPPLTAAGCPRGRGHPGHVQPGAAGA 231
            +G P R   PGG+G  G         + G P        A G P   G PG V P     
Sbjct: 1019 DGLPGRDGSPGGKGDRG---------ENGSP-------GAPGAPGHPGPPGPVGPAGKSG 1062

Query: 232  ELG----SGRGRAPG-AGCRG 247
            + G    +G   APG AG RG
Sbjct: 1063 DRGESGPAGPAGAPGPAGSRG 1083



 Score = 27.7 bits (60), Expect = 9.7
 Identities = 23/62 (37%), Positives = 25/62 (40%), Gaps = 12/62 (19%)

Query: 181 PGGEGPAGRVWRQRSQHDLGRPPVDVPPLTAAGCPRGRGHPGHVQPGAAGAELGSGRGRA 240
           PGG G  G+     SQ + GRP    PP      PRG       QPG  G     G   A
Sbjct: 542 PGGPGSDGKPGPPGSQGESGRPG---PP--GPSGPRG-------QPGVMGFPGPKGNDGA 589

Query: 241 PG 242
           PG
Sbjct: 590 PG 591


>gi|239742114 PREDICTED: similar to hCG2023245 [Homo sapiens]
          Length = 329

 Score = 32.3 bits (72), Expect = 0.40
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 192 RQRSQHDLGRPPVD-VPPLTAAGCPRGRGHPGHVQPGAAGAELGSGRGRAPGAG 244
           +QR+     RP  +  P L  +  PRG   P   +P +A   L  G   +PGAG
Sbjct: 100 QQRAPESQERPAEESAPALMPSSAPRGPTEPAFRRPSSADRPLAPGPSSSPGAG 153


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1751

 Score = 32.3 bits (72), Expect = 0.40
 Identities = 24/62 (38%), Positives = 27/62 (43%), Gaps = 15/62 (24%)

Query: 181  PGGEGPAGRVWRQRSQHDLGRPPVDVPPLTAAGCPRGRGHPGHVQPGAAGAELGSGRGRA 240
            PG EGP GR  ++ S             L  AG P  +G  G   PG AGA   SG   A
Sbjct: 958  PGREGPPGRTGQKGS-------------LGEAGAPGHKGSKG--APGPAGARGESGLAGA 1002

Query: 241  PG 242
            PG
Sbjct: 1003 PG 1004


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,418,627
Number of Sequences: 37866
Number of extensions: 622491
Number of successful extensions: 2785
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 131
Number of HSP's that attempted gapping in prelim test: 2601
Number of HSP's gapped (non-prelim): 310
length of query: 249
length of database: 18,247,518
effective HSP length: 100
effective length of query: 149
effective length of database: 14,460,918
effective search space: 2154676782
effective search space used: 2154676782
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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