BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|223717971 corticotropin releasing hormone receptor 1 isoform 1 [Homo sapiens] (444 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|223717971 corticotropin releasing hormone receptor 1 isoform ... 921 0.0 gi|19923245 corticotropin releasing hormone receptor 1 isoform 2... 840 0.0 gi|223717985 corticotropin releasing hormone receptor 1 isoform ... 801 0.0 gi|223717978 corticotropin releasing hormone receptor 1 isoform ... 732 0.0 gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap... 593 e-169 gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens] 199 4e-51 gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens] 187 1e-47 gi|114205383 secretin receptor precursor [Homo sapiens] 185 8e-47 gi|4502547 calcitonin receptor [Homo sapiens] 184 2e-46 gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens] 181 1e-45 gi|4503947 glucagon receptor [Homo sapiens] 181 1e-45 gi|5031621 calcitonin receptor-like [Homo sapiens] 172 6e-43 gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi... 171 2e-42 gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens] 167 2e-41 gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens] 165 7e-41 gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar... 164 1e-40 gi|58530851 growth hormone releasing hormone receptor isoform a ... 162 6e-40 gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens] 158 8e-39 gi|58530853 growth hormone releasing hormone receptor isoform b ... 109 4e-24 gi|163792198 latrophilin 3 precursor [Homo sapiens] 93 4e-19 gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 91 2e-18 gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 86 5e-17 gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 84 2e-16 gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] 79 8e-15 gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens] 77 4e-14 gi|6912464 latrophilin 2 precursor [Homo sapiens] 76 5e-14 gi|40807489 egf-like module containing, mucin-like, hormone rece... 74 2e-13 gi|240120161 G protein-coupled receptor 144 [Homo sapiens] 74 3e-13 gi|148719671 G-protein coupled receptor 116 [Homo sapiens] 72 8e-13 gi|148719673 G-protein coupled receptor 116 [Homo sapiens] 72 8e-13 >gi|223717971 corticotropin releasing hormone receptor 1 isoform 1 [Homo sapiens] Length = 444 Score = 921 bits (2381), Expect = 0.0 Identities = 444/444 (100%), Positives = 444/444 (100%) Query: 1 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA Sbjct: 1 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60 Query: 61 GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120 GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV Sbjct: 61 GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120 Query: 121 IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR 180 IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR Sbjct: 121 IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR 180 Query: 181 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 240 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC Sbjct: 181 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 240 Query: 241 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 300 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI Sbjct: 241 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 300 Query: 301 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 360 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF Sbjct: 301 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 360 Query: 361 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV 420 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV Sbjct: 361 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV 420 Query: 421 ARAMSIPTSPTRVSFHSIKQSTAV 444 ARAMSIPTSPTRVSFHSIKQSTAV Sbjct: 421 ARAMSIPTSPTRVSFHSIKQSTAV 444 >gi|19923245 corticotropin releasing hormone receptor 1 isoform 2 [Homo sapiens] Length = 415 Score = 840 bits (2171), Expect = 0.0 Identities = 415/444 (93%), Positives = 415/444 (93%), Gaps = 29/444 (6%) Query: 1 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA Sbjct: 1 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60 Query: 61 GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120 GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV Sbjct: 61 GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120 Query: 121 IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR 180 IINYLGHCISLVALLVAFVLFLRLR SIRCLR Sbjct: 121 IINYLGHCISLVALLVAFVLFLRLR-----------------------------SIRCLR 151 Query: 181 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 240 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC Sbjct: 152 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 211 Query: 241 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 300 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI Sbjct: 212 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 271 Query: 301 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 360 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF Sbjct: 272 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 331 Query: 361 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV 420 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV Sbjct: 332 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV 391 Query: 421 ARAMSIPTSPTRVSFHSIKQSTAV 444 ARAMSIPTSPTRVSFHSIKQSTAV Sbjct: 392 ARAMSIPTSPTRVSFHSIKQSTAV 415 >gi|223717985 corticotropin releasing hormone receptor 1 isoform 4 [Homo sapiens] Length = 401 Score = 801 bits (2069), Expect = 0.0 Identities = 401/444 (90%), Positives = 401/444 (90%), Gaps = 43/444 (9%) Query: 1 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA Sbjct: 1 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60 Query: 61 GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120 GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV Sbjct: 61 GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120 Query: 121 IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR 180 IINYLGHCISLVALLVAFVLFLRLR SIRCLR Sbjct: 121 IINYLGHCISLVALLVAFVLFLRLR-----------------------------SIRCLR 151 Query: 181 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 240 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC Sbjct: 152 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 211 Query: 241 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 300 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI Sbjct: 212 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 271 Query: 301 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 360 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF Sbjct: 272 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 331 Query: 361 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV 420 VNPGEDEVSRVVFIYFNSFLESFQ VRSAIRKRWHRWQDKHSIRARV Sbjct: 332 VNPGEDEVSRVVFIYFNSFLESFQ--------------VRSAIRKRWHRWQDKHSIRARV 377 Query: 421 ARAMSIPTSPTRVSFHSIKQSTAV 444 ARAMSIPTSPTRVSFHSIKQSTAV Sbjct: 378 ARAMSIPTSPTRVSFHSIKQSTAV 401 >gi|223717978 corticotropin releasing hormone receptor 1 isoform 3 [Homo sapiens] Length = 375 Score = 732 bits (1889), Expect = 0.0 Identities = 374/444 (84%), Positives = 375/444 (84%), Gaps = 69/444 (15%) Query: 1 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNIS Sbjct: 1 MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNIS-------------------- 40 Query: 61 GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120 +NGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV Sbjct: 41 --------------------DNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 80 Query: 121 IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR 180 IINYLGHCISLVALLVAFVLFLRLR SIRCLR Sbjct: 81 IINYLGHCISLVALLVAFVLFLRLR-----------------------------SIRCLR 111 Query: 181 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 240 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC Sbjct: 112 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 171 Query: 241 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 300 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI Sbjct: 172 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 231 Query: 301 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 360 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF Sbjct: 232 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 291 Query: 361 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV 420 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV Sbjct: 292 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV 351 Query: 421 ARAMSIPTSPTRVSFHSIKQSTAV 444 ARAMSIPTSPTRVSFHSIKQSTAV Sbjct: 352 ARAMSIPTSPTRVSFHSIKQSTAV 375 >gi|32307159 corticotropin releasing hormone receptor 2 [Homo sapiens] Length = 411 Score = 593 bits (1529), Expect = e-169 Identities = 278/402 (69%), Positives = 329/402 (81%), Gaps = 31/402 (7%) Query: 44 CNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQ 103 CN ++D IGTCWPRS AG LV RPCP +F GV+YNTT N YRECL NG+WA+++NYS+C+ Sbjct: 40 CNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCE 99 Query: 104 EILNE-EKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVG 162 IL++ ++K +HY +A+++NYLGHC+S+ AL+ AF+LFL LR Sbjct: 100 PILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALR----------------- 142 Query: 163 APWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTA 222 SIRCLRN+IHWNLI+ FILRN WF++QL + EVH+SN WCR +T Sbjct: 143 ------------SIRCLRNVIHWNLITTFILRNVMWFLLQL-VDHEVHESNEVWCRCITT 189 Query: 223 AYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYY 282 +NYF VTNFFWMF EGCYLHTAIV+TYST+RLRK +F+ IGW +PFPIIVAWAIGKLYY Sbjct: 190 IFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYY 249 Query: 283 DNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAV 342 +NE+CWFGK PG DYIYQGP+ILVLLINF+FLFNIVRILMTKLRASTTSETIQYRKAV Sbjct: 250 ENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAV 309 Query: 343 KATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSA 402 KATLVLLPLLGITYMLFFVNPGED++S+++FIYFNSFL+SFQGFFVSVFYCF N EVRSA Sbjct: 310 KATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSA 369 Query: 403 IRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 444 +RKRWHRWQD HS+R +ARAMSIPTSPTR+SFHSIKQ+ AV Sbjct: 370 VRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV 411 >gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens] Length = 593 Score = 199 bits (506), Expect = 4e-51 Identities = 125/412 (30%), Positives = 184/412 (44%), Gaps = 73/412 (17%) Query: 37 SNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWA-- 94 S G C D I CWP G++V PCP + Y +N + YR C NGSW Sbjct: 101 SRYRGRPCLPEWDHI-LCWPLGAPGEVVAVPCPDYIYD--FNHKGHAYRRCDRNGSWELV 157 Query: 95 -----ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCT 149 NYSEC + L E + + + +I +G+ +SL +L VA ++ R Sbjct: 158 PGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFR---- 213 Query: 150 HWGDQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFV--------- 200 + C RN IH +L +F+LR + FV Sbjct: 214 -------------------------RLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGA 248 Query: 201 ----------------VQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHT 244 Q P + CR+ + YF TN++W+ EG YLH+ Sbjct: 249 TLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHS 308 Query: 245 AIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGP 304 I + + +++ W F GWG+P + W + N CW +I Q P Sbjct: 309 LIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCW--DLSSGNKKWIIQVP 366 Query: 305 MILVLLINFIFLFNIVRILMTKLR---ASTTSETIQYRKAVKATLVLLPLLGITYMLFFV 361 ++ +++NFI NIVR+L TKLR A QYRK +K+TLVL+PL G+ Y++F Sbjct: 367 ILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMA 426 Query: 362 NPGEDEVSRVVF---IYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 410 P EVS ++ +++ SFQGFFV++ YCF N EV++ I+K W RW Sbjct: 427 TP-YTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRW 477 >gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens] Length = 457 Score = 187 bits (476), Expect = 1e-47 Identities = 114/373 (30%), Positives = 185/373 (49%), Gaps = 52/373 (13%) Query: 53 TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYREC-------LANGSWAARVNYSECQEI 105 TCWP +P GQ+VV CP F N R C L G + + Sbjct: 71 TCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAAS 130 Query: 106 LNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAP 164 L+E++ ++ +V Y +G+ +SL LLVA + Sbjct: 131 LDEQQTM---FYGSVKTGYTIGYGLSLATLLVATAIL----------------------- 164 Query: 165 WSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTM-----SPEVHQSNVGWCRL 219 + R + C RN IH +L +FILR A F+ L + S + + +VG C+ Sbjct: 165 ------SLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVG-CKA 217 Query: 220 VTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGK 279 + Y + NFFW+ EG YL+T + +++ ++R W +I IGWGVP + W I + Sbjct: 218 AMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIAR 277 Query: 280 LYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAS--TTSETIQ 337 +++++ CW ++ +I +GP++ +L+NFI I+RIL+ KLR S++ Sbjct: 278 IHFEDYGCWDTINSSLW--WIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSP 335 Query: 338 YRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNS 397 Y + ++TL+L+PL G+ Y++F P D V + F + SFQGF V++ YCFLN Sbjct: 336 YSRLARSTLLLIPLFGVHYIMFAFFP--DNFKPEVKMVFELVVGSFQGFVVAILYCFLNG 393 Query: 398 EVRSAIRKRWHRW 410 EV++ +R++W RW Sbjct: 394 EVQAELRRKWRRW 406 >gi|114205383 secretin receptor precursor [Homo sapiens] Length = 440 Score = 185 bits (469), Expect = 8e-47 Identities = 121/372 (32%), Positives = 190/372 (51%), Gaps = 53/372 (14%) Query: 53 TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNG--YRECLANGSWAA---RVNYSECQEILN 107 +CWP S G++V CP F +R T+ NG +R C +G W+ R N + C +N Sbjct: 74 SCWPSSVPGRMVEVECPRF---LRMLTSRNGSLFRNCTQDG-WSETFPRPNLA-CGVNVN 128 Query: 108 EEKKSKVH-YHVAVIINY-LGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPW 165 + K H Y + + + Y +G+ SLV LLVA + R Sbjct: 129 DSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFR-------------------- 168 Query: 166 SGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTM--SPEVHQSNV--GWCRLVT 221 + C RN IH +L +FILR + F+ + S +V + C+LV Sbjct: 169 ---------RLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVM 219 Query: 222 AAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLY 281 + Y + N+ W+ EG YLHT + +++ ++R F+ GWG P + WAI + + Sbjct: 220 VLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHF 279 Query: 282 YDNEKCW-FGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT--SETIQY 338 ++ CW ++ +I +GP+IL +LINFI NI+RILM KLR T +E Y Sbjct: 280 LEDVGCWDINANASIW--WIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHY 337 Query: 339 RKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSE 398 ++ ++TL+L+PL GI Y++F +P E + + ++F L SFQG V+V YCFLN E Sbjct: 338 KRLARSTLLLIPLFGIHYIVFAFSP---EDAMEIQLFFELALGSFQGLVVAVLYCFLNGE 394 Query: 399 VRSAIRKRWHRW 410 V+ ++K+W +W Sbjct: 395 VQLEVQKKWQQW 406 >gi|4502547 calcitonin receptor [Homo sapiens] Length = 474 Score = 184 bits (466), Expect = 2e-46 Identities = 119/401 (29%), Positives = 196/401 (48%), Gaps = 57/401 (14%) Query: 41 GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV--- 97 G CN + D CW +PAG L + CP +F ++ + + C G W Sbjct: 69 GPYCNRTWDG-WLCWDDTPAGVLSYQFCPDYFPD--FDPSEKVTKYCDEKGVWFKHPENN 125 Query: 98 ----NYSECQEILNEE-KKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWG 152 NY+ C E+ K + V Y++A++ GH +S+ L+++ +F+ R Sbjct: 126 RTWSNYTMCNAFTPEKLKNAYVLYYLAIV----GHSLSIFTLVISLGIFVFFR------- 174 Query: 153 DQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFV--VQLTMSPEVH 210 S+ C R +H N+ +IL + + V++ + E+ Sbjct: 175 ----------------------SLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELV 212 Query: 211 QSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFP 270 + + C+++ + Y N+FWM EG YLHT IV+ T++ R + +GWG P Sbjct: 213 RRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLV 272 Query: 271 IIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAS 330 AI + Y N+ CW + YI GP++ L++NF FL NIVR+L+TK+R + Sbjct: 273 PTTIHAITRAVYFNDNCWLSVETHLL--YIIHGPVMAALVVNFFFLLNIVRVLVTKMRET 330 Query: 331 TTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSV 390 +E+ Y KAVKAT++L+PLLGI +++F P + + ++ Y L FQGFFV+ Sbjct: 331 HEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGK-IYDYVMHSLIHFQGFFVAT 389 Query: 391 FYCFLNSEVRSAIRKRW--------HRWQDKHSIRARVARA 423 YCF N+EV++ ++++W RW + S R+ A A Sbjct: 390 IYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRSARAAA 430 >gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens] Length = 550 Score = 181 bits (459), Expect = 1e-45 Identities = 113/393 (28%), Positives = 175/393 (44%), Gaps = 69/393 (17%) Query: 54 CWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSW-------AARVNYSECQEIL 106 CWPR G++ PCP + Y +N +R C NG+W NYS+C L Sbjct: 72 CWPRGTVGKISAVPCPPYIYD--FNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFL 129 Query: 107 NEEKK-SKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAP 164 + K + + + Y +G+ IS +L VA ++ R Sbjct: 130 QPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFR------------------- 170 Query: 165 WSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTM------------------- 205 + C RN IH +L +F+LR + FV + Sbjct: 171 ----------RLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQ 220 Query: 206 ----SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFI 261 + V +S C++ + YF TN++W+ EG YLH I + + +D W FI Sbjct: 221 NSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFI 280 Query: 262 CIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVR 321 IGWG P + AWA+ + + +CW + +IYQ P++ + +NFI N VR Sbjct: 281 LIGWGFPAAFVAAWAVARATLADARCWELSAGDI--KWIYQAPILAAIGLNFILFLNTVR 338 Query: 322 ILMTKL---RASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGE-DEVSRVVFIYFN 377 +L TK+ A QYRK K+TLVL+ + G+ Y++F P + + ++ Sbjct: 339 VLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCE 398 Query: 378 SFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 410 F SFQGFFVS+ YC+ N EV++ ++K W RW Sbjct: 399 LFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRW 431 >gi|4503947 glucagon receptor [Homo sapiens] Length = 477 Score = 181 bits (459), Expect = 1e-45 Identities = 133/446 (29%), Positives = 202/446 (45%), Gaps = 71/446 (15%) Query: 5 PQLRLVKALLLLGLNPVSASLQ-------------DQHCESLSLASNISGLQCNASVDLI 51 PQ L+ LLLL P S Q DQ +LSL + L CN + D Sbjct: 6 PQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKY 65 Query: 52 GTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV------NYSECQ-- 103 +CWP +PA CP + ++ C +G W + S+CQ Sbjct: 66 -SCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMD 124 Query: 104 -EILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVG 162 E + +K+ Y ++ +G+ +SL ALL+A + G L Sbjct: 125 GEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAIL---------------GGLS-- 167 Query: 163 APWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQ--------------LTMSPE 208 + C RN IH NL ++F+L+ ++ V+ L++S Sbjct: 168 ------------KLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTW 215 Query: 209 VHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVP 268 + V CR+ Y V N+ W+ EG YLH + L +R +++ IGWG P Sbjct: 216 LSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAP 275 Query: 269 FPIIVAWAIGKLYYDNEKCWFGK-RPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKL 327 +V WA+ K ++N +CW G + +I + P+ L +LINF IV++L+ KL Sbjct: 276 MLFVVPWAVVKCLFENVQCWTSNDNMGFW--WILRFPVFLAILINFFIFVRIVQLLVAKL 333 Query: 328 RASTTSETIQYRKAVKATLVLLPLLGITYMLF-FVNPGEDE-VSRVVFIYFNSFLESFQG 385 RA T + K+TL L+PLLG+ ++F FV + R ++F+ FL SFQG Sbjct: 334 RARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQG 393 Query: 386 FFVSVFYCFLNSEVRSAIRKRWHRWQ 411 V+V YCFLN EV+S +R+RWHRW+ Sbjct: 394 LLVAVLYCFLNKEVQSELRRRWHRWR 419 >gi|5031621 calcitonin receptor-like [Homo sapiens] Length = 461 Score = 172 bits (436), Expect = 6e-43 Identities = 111/381 (29%), Positives = 184/381 (48%), Gaps = 49/381 (12%) Query: 41 GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAAR---- 96 G+ CN + D CW AG ++ CP +F ++ + + C +G+W Sbjct: 62 GVYCNRTWDG-WLCWNDVAAGTESMQLCPDYFQD--FDPSEKVTKICDQDGNWFRHPASN 118 Query: 97 ---VNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGD 153 NY++C +E+ K+ ++ II GH +S+ +LL++ +F + Sbjct: 119 RTWTNYTQCNVNTHEKVKTALNLFYLTII---GHGLSIASLLISLGIFFYFK-------- 167 Query: 154 QADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTM---SPEVH 210 S+ C R +H NL +F+ N+ ++ LT + + Sbjct: 168 ---------------------SLSCQRITLHKNLFFSFVC-NSVVTIIHLTAVANNQALV 205 Query: 211 QSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFP 270 +N C++ + Y N+FWM EG YLHT IV+ ++ + +GWG P Sbjct: 206 ATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLI 265 Query: 271 IIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAS 330 AI + Y N+ CW + YI GP+ LL+N FL NIVR+L+TKL+ + Sbjct: 266 PACIHAIARSLYYNDNCWISS--DTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVT 323 Query: 331 TTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSV 390 +E+ Y KAV+ATL+L+PLLGI ++L P E +++ V+ Y L FQG VS Sbjct: 324 HQAESNLYMKAVRATLILVPLLGIEFVLIPWRP-EGKIAEEVYDYIMHILMHFQGLLVST 382 Query: 391 FYCFLNSEVRSAIRKRWHRWQ 411 +CF N EV++ +R+ W++++ Sbjct: 383 IFCFFNGEVQAILRRNWNQYK 403 >gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapiens] Length = 553 Score = 171 bits (432), Expect = 2e-42 Identities = 128/444 (28%), Positives = 199/444 (44%), Gaps = 74/444 (16%) Query: 3 GHPQLRLVKALLLLGLNPVSASLQDQHCESLS---------LASNISGLQCNASVDLIGT 53 G P L LV LL+ + V+ SL ++ + L SG+ CN + D Sbjct: 49 GRPFLTLV---LLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQY-V 104 Query: 54 CWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNY-------SECQEIL 106 CWP S G + V PCP++ ++ YR CLA G+W N SEC E Sbjct: 105 CWPHSSPGNVSV-PCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSE-- 161 Query: 107 NEEKKSKVHYHVAV----IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVG 162 N K V + + ++ +G+ SL++L +A L L L Sbjct: 162 NHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFL------------------ 203 Query: 163 APWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQ---SNVGW--- 216 R + C RN IH NL ++FILR V + + + GW Sbjct: 204 -----------RKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSY 252 Query: 217 -------CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKW-MFICIGWGVP 268 CR V +YF N+ W+ EG YLHT + T +R R W ++ +GW P Sbjct: 253 LSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPER-RLWPRYLLLGWAFP 311 Query: 269 FPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLR 328 +V W + + +N CW +I +GPM+L + +NF I+++L++KL+ Sbjct: 312 VLFVVPWGFARAHLENTGCW-TTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLK 370 Query: 329 ASTTSETIQYRKAVKATLVLLPLLGITYMLF-FVNPGEDE-VSRVVFIYFNSFLESFQGF 386 A + K+TLVL+PLLG+ +LF F+ + E ++++ ++ L SF GF Sbjct: 371 AHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGF 430 Query: 387 FVSVFYCFLNSEVRSAIRKRWHRW 410 V++ Y F N EV++ +RK W R+ Sbjct: 431 LVALQYGFANGEVKAELRKYWVRF 454 >gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens] Length = 438 Score = 167 bits (423), Expect = 2e-41 Identities = 115/393 (29%), Positives = 185/393 (47%), Gaps = 47/393 (11%) Query: 26 QDQHCESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYR 85 ++ C L + C+ D I TCW + G+ V PCP F Y+ N + Sbjct: 34 EETKCAELLRSQTEKHKACSGVWDNI-TCWRPANVGETVTVPCPKVFSNF-YSKAGNISK 91 Query: 86 ECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRL 144 C ++G ++ + + E +SK+ +++ V Y LG+ +SL++L ++ Sbjct: 92 NCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLF 151 Query: 145 RPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLT 204 R + C RN IH NL +FILR + V Sbjct: 152 R-----------------------------KLHCTRNYIHLNLFLSFILRAISVLVKDDV 182 Query: 205 M--------SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLR 256 + P+ S VG C+L Y + NFFW+ EG YLHT +V R Sbjct: 183 LYSSSGTLHCPDQPSSWVG-CKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCF 241 Query: 257 KWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFL 316 ++ IGWG+P I AW +LY ++ CW V ++ + P+++ +++NF+ Sbjct: 242 L-AYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPW-WVIRIPILISIIVNFVLF 299 Query: 317 FNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFI 374 +I+RIL+ KL + ++ QY++ K+TL+L+PL G+ YM+F V P +S I Sbjct: 300 ISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFP--ISISSKYQI 357 Query: 375 YFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRW 407 F L SFQG V+V YCFLNSEV+ ++++W Sbjct: 358 LFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390 >gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens] Length = 463 Score = 165 bits (418), Expect = 7e-41 Identities = 116/403 (28%), Positives = 183/403 (45%), Gaps = 68/403 (16%) Query: 42 LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVN--- 98 L CN + D CWP G V CP + + YR C A G W + N Sbjct: 60 LFCNRTFDEYA-CWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSL 118 Query: 99 ----YSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRPGCTHWGD 153 SEC+E E+ S + + I Y +G+ +S AL++A + L R Sbjct: 119 PWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFR-------- 170 Query: 154 QADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTM------SP 207 + C RN IH NL ++FILR + F+ + + Sbjct: 171 ---------------------HLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAA 209 Query: 208 EVHQSNVGW-----------CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLR 256 + HQ W CRLV Y N++W+ EG YL+T + + +++ Sbjct: 210 QQHQ----WDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWI 265 Query: 257 KWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFL 316 +++ IGWGVP +V W I K Y++E CW + + I + P++ + +NF+ Sbjct: 266 FRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCW-TRNSNMNYWLIIRLPILFAIGVNFLIF 324 Query: 317 FNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLF-FVNPGEDEVSRVVFIY 375 ++ I+++KL+A+ +T + K+TL L+PLLG ++F FV DE +R + Sbjct: 325 VRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFV---MDEHARGTLRF 381 Query: 376 FNSFLE----SFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKH 414 F E SFQG V++ YCF+N+EV+ RK W RW+ +H Sbjct: 382 IKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEH 424 >gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I precursor [Homo sapiens] Length = 468 Score = 164 bits (415), Expect = 1e-40 Identities = 125/448 (27%), Positives = 201/448 (44%), Gaps = 87/448 (19%) Query: 12 ALLLLGLNPVSAS------LQDQHCESLSLASNISGLQ-----CNASVDLIGTCWPRSPA 60 ALLLL + P S Q E + A+ + G C D I TCW + Sbjct: 11 ALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNI-TCWKPAHV 69 Query: 61 GQLVVRPCPAFF------------------YG------------VRYNTTNNGYRECLAN 90 G++V+ CP F +G V N T +G+ E + Sbjct: 70 GEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPH 129 Query: 91 GSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRPGCT 149 A + E E + +Y+++V Y +G+ SLV L A V+ R R Sbjct: 130 YFDACGFDEYE------SETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFR---- 179 Query: 150 HWGDQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 209 + C RN IH NL +F+LR + F+ + E Sbjct: 180 -------------------------KLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQ 214 Query: 210 HQSN----VGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGW 265 ++ C+ V ++Y V+N+FW+F EG YL T +V T+ +R + + IGW Sbjct: 215 DSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGW 274 Query: 266 GVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMT 325 G P + WA +LY+D+ CW ++ +GP++ +++NF+ I+ IL+ Sbjct: 275 GTPTVCVTVWATLRLYFDDTGCW-DMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQ 333 Query: 326 KLRASTT--SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESF 383 KL++ +E+ Y + ++TL+L+PL GI Y +F +P + VS+ + F L SF Sbjct: 334 KLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSP--ENVSKRERLVFELGLGSF 391 Query: 384 QGFFVSVFYCFLNSEVRSAIRKRWHRWQ 411 QGF V+V YCFLN EV++ I+++W W+ Sbjct: 392 QGFVVAVLYCFLNGEVQAEIKRKWRSWK 419 >gi|58530851 growth hormone releasing hormone receptor isoform a precursor [Homo sapiens] Length = 423 Score = 162 bits (410), Expect = 6e-40 Identities = 115/380 (30%), Positives = 174/380 (45%), Gaps = 53/380 (13%) Query: 42 LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94 L C A+ D + CWP + +G+ V PCP FF V+ + T G+ E A Sbjct: 53 LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111 Query: 95 ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQ 154 V E+L EE+ ++ II +GH IS+VAL VA + + LR Sbjct: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALR--------- 155 Query: 155 ADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNV 214 + C RN +H L + FIL+ F+ + + Sbjct: 156 --------------------RLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHC 195 Query: 215 GW----CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFP 270 + C++ AA ++ +TNF W+ E YL+ + T + R W + GWG+P Sbjct: 196 SFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVL 255 Query: 271 IIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAS 330 W KL +++ CW Y +I +GP++L + +NF NI+RIL+ KL + Sbjct: 256 FTGTWVSCKLAFEDIACWDLDDTSPYW-WIIKGPIVLSVGVNFGLFLNIIRILVRKLEPA 314 Query: 331 TTS--ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFV 388 S QY + K+TL L+PL GI Y++F P D + + L SFQGF V Sbjct: 315 QGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLP--DNAGLGIRLPLELGLGSFQGFIV 372 Query: 389 SVFYCFLNSEVRSAIRKRWH 408 ++ YCFLN EVR+ I ++WH Sbjct: 373 AILYCFLNQEVRTEISRKWH 392 >gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens] Length = 466 Score = 158 bits (400), Expect = 8e-39 Identities = 112/405 (27%), Positives = 184/405 (45%), Gaps = 55/405 (13%) Query: 31 ESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLAN 90 E+L+ A SGL CN S D+ CW + CP + + R+C ++ Sbjct: 48 ETLAAAEPPSGLACNGSFDMY-VCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSD 106 Query: 91 GSWAARVNYSECQEILNEEKKS-----KVHYHVAVIINYLGHCISLVALLVAFVLFLRLR 145 G W ++++C+ N EK ++ ++ +G+ +SL LL+A ++ Sbjct: 107 GQWGLWRDHTQCE---NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLIL---- 159 Query: 146 PGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVV-QLT 204 + R + C RN IH NL ++F+LR A +L Sbjct: 160 -------------------------SLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLL 194 Query: 205 MSPEVH---QSNVGW------CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRL 255 P + Q+ W CR Y N+ W+ EG YLH+ +VL ++ Sbjct: 195 PRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEG 254 Query: 256 RKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIF 315 ++ +GWG P ++ W I + Y+N +CW +I + P+++ +LINF+ Sbjct: 255 HFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIW-WIIRTPILMTILINFLI 313 Query: 316 LFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIY 375 I+ IL++KLR + ++TL L+PLLG+ ++F P +E +R + Sbjct: 314 FIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVF--APVTEEQARGALRF 371 Query: 376 ----FNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSI 416 F FL SFQGF VSV YCF+N EV+S IR+ WH + + S+ Sbjct: 372 AKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSL 416 >gi|58530853 growth hormone releasing hormone receptor isoform b precursor [Homo sapiens] Length = 337 Score = 109 bits (273), Expect = 4e-24 Identities = 83/303 (27%), Positives = 130/303 (42%), Gaps = 49/303 (16%) Query: 42 LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94 L C A+ D + CWP + +G+ V PCP FF V+ + T G+ E A Sbjct: 53 LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111 Query: 95 ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQ 154 V E+L EE+ ++ II +GH IS+VAL VA + + LR Sbjct: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALR--------- 155 Query: 155 ADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNV 214 + C RN +H L + FIL+ F+ + + Sbjct: 156 --------------------RLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHC 195 Query: 215 GW----CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFP 270 + C++ AA ++ +TNF W+ E YL+ + T + R W + GWG+P Sbjct: 196 SFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVL 255 Query: 271 IIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAS 330 W KL +++ CW Y +I +GP++L + +NF NI+RIL+ KL + Sbjct: 256 FTGTWVSCKLAFEDIACWDLDDTSPYW-WIIKGPIVLSVGVNFGLFLNIIRILVRKLEPA 314 Query: 331 TTS 333 S Sbjct: 315 QGS 317 >gi|163792198 latrophilin 3 precursor [Homo sapiens] Length = 1469 Score = 93.2 bits (230), Expect = 4e-19 Identities = 93/351 (26%), Positives = 145/351 (41%), Gaps = 69/351 (19%) Query: 74 GVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVA 133 G R TTN + C N N++ + + VH + +I ++G +SLV Sbjct: 836 GCRLLTTNKTHTTCSCNHL----TNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVC 891 Query: 134 LLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNL-ISAFI 192 LL+ F C G Q+D RN IH NL IS F+ Sbjct: 892 LLICIFTF------CFFRGLQSD-----------------------RNTIHKNLCISLFV 922 Query: 193 LRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYST 252 + T P C + A ++F + F WMF EG L+ +V + + Sbjct: 923 AELLFLIGINRTDQPIA-------CAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFES 975 Query: 253 DRLRKWMFICIGWGVPFPII-VAWAIGKLYYDNEK-CWFGKRPGVYTDYIYQGPMILVLL 310 + R+ F +G+G+P I+ V+ A+ Y +K CW R Y + + GP L+++ Sbjct: 976 EHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWL--RLDTYFIWSFIGPATLIIM 1033 Query: 311 INFIFL-------FNIVRILMTKLRASTTSETIQY-------RKAVKATLVLLPLLGITY 356 +N IFL F+ IL + S + I Y + V + LL LLG+T+ Sbjct: 1034 LNVIFLGIALYKMFHHTAILKPE---SGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTW 1090 Query: 357 M--LFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRK 405 L ++N S V+ Y + S QG F+ +F+C L +VR K Sbjct: 1091 AFGLMYINE-----STVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGK 1136 >gi|45433552 G protein-coupled receptor 133 [Homo sapiens] Length = 874 Score = 90.9 bits (224), Expect = 2e-18 Identities = 65/252 (25%), Positives = 121/252 (48%), Gaps = 26/252 (10%) Query: 170 FQVRRSIRCLRNI---IHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNY 226 F V S+ +RN IH NL A ++ ++ + P C+++ +Y Sbjct: 588 FAVLSSVSTIRNQRYHIHANLSFAVLVAQVL-LLISFRLEPGTTP-----CQVMAVLLHY 641 Query: 227 FHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIV---AWAIGKLYYD 283 F ++ F WM EG +L++ ++ + ++ + + +GWG P I + ++A+ Y Sbjct: 642 FFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFAMDS-YGT 700 Query: 284 NEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTS---ETIQYRK 340 + CW G ++ P + V+++N L + R++ +++ A + ++ Sbjct: 701 SNNCWLSLASGAIWAFV--APALFVIVVNIGILIAVTRVI-SQISADNYKIHGDPSAFKL 757 Query: 341 AVKATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSE 398 KA VLLP+LG +++ + VN VVF Y + L S QG F+ +F+C LNSE Sbjct: 758 TAKAVAVLLPILGTSWVFGVLAVNG-----CAVVFQYMFATLNSLQGLFIFLFHCLLNSE 812 Query: 399 VRSAIRKRWHRW 410 VR+A + + W Sbjct: 813 VRAAFKHKTKVW 824 >gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo sapiens] Length = 652 Score = 86.3 bits (212), Expect = 5e-17 Identities = 82/303 (27%), Positives = 130/303 (42%), Gaps = 54/303 (17%) Query: 118 VAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIR 177 V +I Y+G +SL+ LL+A + FL + ++IR Sbjct: 355 VLTVITYVGLSVSLLCLLLAALTFL-----------------------------LCKAIR 385 Query: 178 CLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFG 237 +H L L + + V P+V C ++ A +Y ++ F WM Sbjct: 386 NTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKV------LCSIIAGALHYLYLAAFTWMLL 439 Query: 238 EGCYL----HTAIVLTYST-DRLRKWMFICIGWGVPFPIIVAWAIG--KLYYDNEKCWFG 290 EG +L V+ YS+ +RL KW+ +G+GVP + A LY ++CW Sbjct: 440 EGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLH 499 Query: 291 KRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSE--TIQYRK--AVKATL 346 G ++ GP+ + N + + IL KL +S SE TIQ + A KAT Sbjct: 500 LDQGFMWSFL--GPVCAIFSANLVLFILVFWILKRKL-SSLNSEVSTIQNTRMLAFKATA 556 Query: 347 VLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKR 406 L +LG T+ L + G + V Y + + S QGFF+ + YC L+ +V+ +K Sbjct: 557 QLF-ILGCTWCLGLLQVGP---AAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQK- 611 Query: 407 WHR 409 W R Sbjct: 612 WFR 614 >gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo sapiens] Length = 1584 Score = 84.3 bits (207), Expect = 2e-16 Identities = 66/243 (27%), Positives = 118/243 (48%), Gaps = 24/243 (9%) Query: 172 VRRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTN 231 V R IR R++I N + I NA L + + N C LV A ++F +++ Sbjct: 972 VWRYIRSERSVILINFCLSIISSNA------LILIGQTQTRNKVVCTLVAAFLHFFFLSS 1025 Query: 232 FFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIG----KLYYDNEKC 287 F W+ E + A+ + +RL + F+C+GWG+P ++VA ++G K Y C Sbjct: 1026 FCWVLTEAWQSYMAVT-GHLRNRLIRKRFLCLGWGLP-ALVVAISVGFTKAKGYSTMNYC 1083 Query: 288 WFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVK--AT 345 W G+ Y + GP V+L+N + + L++K T + ++ R ++ Sbjct: 1084 WLSLEGGLL--YAFVGPAAAVVLVNMVIGILVFNKLVSK--DGITDKKLKERAGASLWSS 1139 Query: 346 LVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAI 403 V+LPLL +T+M + V + +++F F +S +GF + + +C L EV+ A+ Sbjct: 1140 CVVLPLLALTWMSAVLAVTDRRSALFQILFAVF----DSLEGFVIVMVHCILRREVQDAV 1195 Query: 404 RKR 406 + R Sbjct: 1196 KCR 1198 >gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] Length = 1522 Score = 79.0 bits (193), Expect = 8e-15 Identities = 79/276 (28%), Positives = 124/276 (44%), Gaps = 49/276 (17%) Query: 174 RSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFF 233 R IR R+II N + I N ++ L + H ++ C TA ++F + +F Sbjct: 904 RYIRSERSIILINFCLSIISSN----ILILVGQTQTHNKSI--CTTTTAFLHFFFLASFC 957 Query: 234 WMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIG----KLYYDNEKCWF 289 W+ E + A+ T +RK F+C+GWG+P ++VA ++G K Y + CW Sbjct: 958 WVLTEAWQSYMAVTGKIRTRLIRK-RFLCLGWGLP-ALVVATSVGFTRTKGYGTDHYCWL 1015 Query: 290 GKRPGVYTDYIYQGPMILVLLINF---IFLFNIV----RILMTKL--RASTTSE-----T 335 G+ Y + GP V+L+N I +FN + IL KL RA SE T Sbjct: 1016 SLEGGLL--YAFVGPAAAVVLVNMVIGILVFNKLVSRDGILDKKLKHRAGQMSEPHSGLT 1073 Query: 336 IQYRK-------AVKAT------------LVLLPLLGITYMLFFVNPGEDEVSRVVFIYF 376 ++ K A+ AT V+LPLL +T+M + + ++F Sbjct: 1074 LKCAKCGVVSTTALSATTASNAMASLWSSCVVLPLLALTWMSAVL--AMTDKRSILFQIL 1131 Query: 377 NSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQD 412 + +S QGF + + +C L EV+ A R R QD Sbjct: 1132 FAVFDSLQGFVIVMVHCILRREVQDAFRCRLRNCQD 1167 >gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens] Length = 910 Score = 76.6 bits (187), Expect = 4e-14 Identities = 66/267 (24%), Positives = 118/267 (44%), Gaps = 26/267 (9%) Query: 188 ISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIV 247 I+ +L WF+V T+ V+ S V C ++F+++ FFWM G L I+ Sbjct: 630 IALSLLIADVWFIVGATVDTTVNPSGV--CTAAVFFTHFFYLSLFFWMLMLGILLAYRII 687 Query: 248 LTYS--TDRLRKWMFICIGWGVPFPI-IVAWAI---GKLYYDNEKCWFGKRPGVYTDYIY 301 L + L + C+G+G P I ++ A+ Y + CW G + Sbjct: 688 LVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAF 747 Query: 302 QGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQ------YRKAVKATLVLLPLLGIT 355 P + ++ +NF+ +V +++TKL T E + + K+ L+L PLLG+T Sbjct: 748 VVPALAIVAVNFV----VVLLVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLT 803 Query: 356 YMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKR------WHR 409 + F + D + + F + L +FQGFF+ F L+S++R + + W + Sbjct: 804 WG-FGIGTIVDSQNLAWHVIF-ALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSWKQ 861 Query: 410 WQDKHSIRARVARAMSIPTSPTRVSFH 436 + ++S S P +P + H Sbjct: 862 TEKQNSSDLSAKPKFSKPFNPLQNKGH 888 >gi|6912464 latrophilin 2 precursor [Homo sapiens] Length = 1403 Score = 76.3 bits (186), Expect = 5e-14 Identities = 81/305 (26%), Positives = 125/305 (40%), Gaps = 56/305 (18%) Query: 111 KSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPF 170 K VH + +I ++G ISLV L + F C G Q+D Sbjct: 826 KDGVHELLLTVITWVGIVISLVCLAICIFTF------CFFRGLQSD-------------- 865 Query: 171 QVRRSIRCLRNIIHWNL-ISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHV 229 RN IH NL I+ FI F+ + + + C + ++F + Sbjct: 866 ---------RNTIHKNLCINLFIAE----FIFLIGIDKTKYAIA---CPIFAGLLHFFFL 909 Query: 230 TNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPII-VAWAIGKLYYDNEK-C 287 F WM EG L+ +V + ++ RK + G+ P ++ V+ AI Y EK C Sbjct: 910 AAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKAC 969 Query: 288 WFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT-----SETIQYRKAV 342 W Y + + GP+ ++L+N IFL V L ++ S T S + V Sbjct: 970 WL--HVDNYFIWSFIGPVTFIILLNIIFL---VITLCKMVKHSNTLKPDSSRLENIKSWV 1024 Query: 343 KATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVR 400 LL LLG+T+ L F+N +V Y + +FQG F+ +F+C L +VR Sbjct: 1025 LGAFALLCLLGLTWSFGLLFINE-----ETIVMAYLFTIFNAFQGVFIFIFHCALQKKVR 1079 Query: 401 SAIRK 405 K Sbjct: 1080 KEYGK 1084 >gi|40807489 egf-like module containing, mucin-like, hormone receptor-like sequence 1 [Homo sapiens] Length = 886 Score = 74.3 bits (181), Expect = 2e-13 Identities = 81/326 (24%), Positives = 139/326 (42%), Gaps = 64/326 (19%) Query: 121 IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR 180 II+++G ISLV L++A FL + RSIR Sbjct: 604 IISHVGIIISLVCLVLAIATFL-----------------------------LCRSIRNHN 634 Query: 181 NIIHWNLISAFILRNATWFVVQLTMSPEVHQS-NVGWCRLVTAAYNYFHVTNFFWMFGEG 239 +H +L +L + +H++ N C ++ +Y + FFWM E Sbjct: 635 TYLHLHLCVCLLLAKTLFLA-------GIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEA 687 Query: 240 CYLHTAI----VLTYSTDRLRKWMFIC-IGWGVPFPIIVAWAIGKL--YYDNEKCWFGKR 292 L + V+ Y + R K + IC G+G+P ++V A + Y + +CW Sbjct: 688 VILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTE 747 Query: 293 PGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA-----STTSETIQYRKAVKATLV 347 G ++ GP+ V++IN + L + IL +L + ST +T R Sbjct: 748 TGFIWSFL--GPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDT---RLLTFKAFA 802 Query: 348 LLPLLGITYML--FFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRK 405 L +LG +++L F + P V Y + + S QG F+ + +C LN +VR K Sbjct: 803 QLFILGCSWVLGIFQIGPVAG-----VMAYLFTIINSLQGAFIFLIHCLLNGQVREEY-K 856 Query: 406 RWHRWQDKHSIRARVARAM--SIPTS 429 RW + K S +++ +R + S+P++ Sbjct: 857 RWITGKTKPSSQSQTSRILLSSMPSA 882 >gi|240120161 G protein-coupled receptor 144 [Homo sapiens] Length = 963 Score = 73.6 bits (179), Expect = 3e-13 Identities = 71/244 (29%), Positives = 107/244 (43%), Gaps = 37/244 (15%) Query: 180 RNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEG 239 R +H NL F L +A F+ M+ E ++N C VT A ++ + F WM EG Sbjct: 690 RTTVHKNL--TFSLASAEGFL----MTSEWAKANEVACVAVTVAMHFLFLVAFSWMLVEG 743 Query: 240 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEK---CWFGKRPGVY 296 L +V ++ GWGVP I VA + L +D CW V+ Sbjct: 744 LLLWRKVVAVSMHPGPGMRLYHATGWGVPVGI-VAVTLAMLPHDYVAPGHCWLN----VH 798 Query: 297 TDYIYQ--GPMILVLLINFIFLFNIVRILMTKLRASTTSET----------IQYRKAVKA 344 T+ I+ GP++ VL N L +V I ++ R + Q VK Sbjct: 799 TNAIWAFVGPVLFVLTANTCILARVVMITVSSARRRARMLSPQPCLQQQIWTQIWATVKP 858 Query: 345 TLVLLPLLGITYM---LFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRS 401 LVLLP+LG+T++ L ++P + Y L S QG ++ + Y N EVRS Sbjct: 859 VLVLLPVLGLTWLAGILVHLSPA--------WAYAAVGLNSIQGLYIFLVYAACNEEVRS 910 Query: 402 AIRK 405 A+++ Sbjct: 911 ALQR 914 >gi|148719671 G-protein coupled receptor 116 [Homo sapiens] Length = 1346 Score = 72.4 bits (176), Expect = 8e-13 Identities = 66/244 (27%), Positives = 114/244 (46%), Gaps = 25/244 (10%) Query: 188 ISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIV 247 I+A +L TWF+V + + C T ++F+++ FFWM G L +V Sbjct: 1057 IAASLLVANTWFIVVAAIQDNRYILCKTACVAATFFIHFFYLSVFFWMLTLGLMLFYRLV 1116 Query: 248 -LTYSTDR-LRKWMFICIGWGVPFPIIV----AWAIGKLYYDNEKCWFGKRPGVYTDYIY 301 + + T R +K + C+G+G P I V A ++Y CW + Sbjct: 1117 FILHETSRSTQKAIAFCLGYGCPLAISVITLGATQPREVYTRKNVCWLNWED-TKALLAF 1175 Query: 302 QGPMILVLLINFIFLFNIVRILMTK-LRASTTSETIQYRKAV-----KATLVLLPLLGIT 355 P ++++++N I +++TK LR S + + K+ K+ VL PLLG+T Sbjct: 1176 AIPALIIVVVNI----TITIVVITKILRPSIGDKPCKQEKSSLFQISKSIGVLTPLLGLT 1231 Query: 356 --YMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRW--HRWQ 411 + L V PG + V ++F + L FQG F+ +F C + +V+ A+ ++ RW Sbjct: 1232 WGFGLTTVFPGTNLVFHIIF----AILNVFQGLFILLFGCLWDLKVQEALLNKFSLSRWS 1287 Query: 412 DKHS 415 +HS Sbjct: 1288 SQHS 1291 >gi|148719673 G-protein coupled receptor 116 [Homo sapiens] Length = 1346 Score = 72.4 bits (176), Expect = 8e-13 Identities = 66/244 (27%), Positives = 114/244 (46%), Gaps = 25/244 (10%) Query: 188 ISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIV 247 I+A +L TWF+V + + C T ++F+++ FFWM G L +V Sbjct: 1057 IAASLLVANTWFIVVAAIQDNRYILCKTACVAATFFIHFFYLSVFFWMLTLGLMLFYRLV 1116 Query: 248 -LTYSTDR-LRKWMFICIGWGVPFPIIV----AWAIGKLYYDNEKCWFGKRPGVYTDYIY 301 + + T R +K + C+G+G P I V A ++Y CW + Sbjct: 1117 FILHETSRSTQKAIAFCLGYGCPLAISVITLGATQPREVYTRKNVCWLNWED-TKALLAF 1175 Query: 302 QGPMILVLLINFIFLFNIVRILMTK-LRASTTSETIQYRKAV-----KATLVLLPLLGIT 355 P ++++++N I +++TK LR S + + K+ K+ VL PLLG+T Sbjct: 1176 AIPALIIVVVNI----TITIVVITKILRPSIGDKPCKQEKSSLFQISKSIGVLTPLLGLT 1231 Query: 356 --YMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRW--HRWQ 411 + L V PG + V ++F + L FQG F+ +F C + +V+ A+ ++ RW Sbjct: 1232 WGFGLTTVFPGTNLVFHIIF----AILNVFQGLFILLFGCLWDLKVQEALLNKFSLSRWS 1287 Query: 412 DKHS 415 +HS Sbjct: 1288 SQHS 1291 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.328 0.140 0.461 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,410,285 Number of Sequences: 37866 Number of extensions: 698200 Number of successful extensions: 2101 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 56 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 1849 Number of HSP's gapped (non-prelim): 160 length of query: 444 length of database: 18,247,518 effective HSP length: 105 effective length of query: 339 effective length of database: 14,271,588 effective search space: 4838068332 effective search space used: 4838068332 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.