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Search of human proteins with 223555963
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223555963 Hsp70 subfamily B suppressor 1-like protein
isoform 2 [Homo sapiens]
(642 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform... 1275 0.0
gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1... 1255 0.0
gi|46094014 peptide chain release factor 3 [Homo sapiens] 347 2e-95
gi|194018522 G1 to S phase transition 1 isoform 3 [Homo sapiens] 344 1e-94
gi|194097354 G1 to S phase transition 1 isoform 2 [Homo sapiens] 344 1e-94
gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens] 344 1e-94
gi|4503471 eukaryotic translation elongation factor 1 alpha 1 [H... 321 1e-87
gi|4503475 eukaryotic translation elongation factor 1 alpha 2 [H... 321 1e-87
gi|239757543 PREDICTED: similar to eukaryotic translation elonga... 270 4e-72
gi|223633995 Hsp70 subfamily B suppressor 1-like protein isoform... 187 3e-47
gi|34147630 Tu translation elongation factor, mitochondrial prec... 142 1e-33
gi|82546879 GTP binding protein 1 [Homo sapiens] 82 1e-15
gi|54607086 eukaryotic elongation factor, selenocysteine-tRNA-sp... 79 1e-14
gi|45593140 GTP binding protein 2 [Homo sapiens] 78 3e-14
gi|157426893 GUF1 GTPase homolog [Homo sapiens] 75 2e-13
gi|239752724 PREDICTED: similar to hCG1981735 [Homo sapiens] 69 2e-11
gi|169162126 PREDICTED: similar to hCG1981735 [Homo sapiens] 69 2e-11
gi|169162824 PREDICTED: similar to hCG1981735 [Homo sapiens] 69 2e-11
gi|169217153 PREDICTED: similar to EEF1A1 protein [Homo sapiens] 67 4e-11
gi|113430525 PREDICTED: similar to EEF1A1 protein [Homo sapiens] 67 4e-11
gi|113429979 PREDICTED: similar to EEF1A1 protein [Homo sapiens] 67 4e-11
gi|53729339 mitochondrial translational initiation factor 2 prec... 58 3e-08
gi|53729337 mitochondrial translational initiation factor 2 prec... 58 3e-08
gi|18390331 G elongation factor, mitochondrial 1 [Homo sapiens] 58 3e-08
gi|239756373 PREDICTED: similar to elongation factor Tu GTP bind... 53 8e-07
gi|239750897 PREDICTED: similar to elongation factor Tu GTP bind... 53 8e-07
gi|239745282 PREDICTED: similar to elongation factor Tu GTP bind... 53 8e-07
gi|94966754 elongation factor Tu GTP binding domain containing 1... 53 8e-07
gi|25306287 mitochondrial elongation factor G2 isoform 2 [Homo s... 52 2e-06
gi|25306283 mitochondrial elongation factor G2 isoform 3 [Homo s... 52 2e-06
>gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform 2
[Homo sapiens]
Length = 642
Score = 1275 bits (3300), Expect = 0.0
Identities = 642/642 (100%), Positives = 642/642 (100%)
Query: 1 MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTARLYSCLDHMREVLGDAVPDEILI 60
MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTARLYSCLDHMREVLGDAVPDEILI
Sbjct: 1 MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTARLYSCLDHMREVLGDAVPDEILI 60
Query: 61 EAVLKNKFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKV 120
EAVLKNKFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKV
Sbjct: 61 EAVLKNKFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKV 120
Query: 121 AKMTVSGKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTI 180
AKMTVSGKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTI
Sbjct: 121 AKMTVSGKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTI 180
Query: 181 QASEEQSSTPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLY 240
QASEEQSSTPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLY
Sbjct: 181 QASEEQSSTPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLY 240
Query: 241 LLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITL 300
LLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITL
Sbjct: 241 LLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITL 300
Query: 301 MDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLA 360
MDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLA
Sbjct: 301 MDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLA 360
Query: 361 VAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELT 420
VAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELT
Sbjct: 361 VAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELT 420
Query: 421 KWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLA 480
KWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLA
Sbjct: 421 KWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLA 480
Query: 481 MPPNETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFR 540
MPPNETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFR
Sbjct: 481 MPPNETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFR 540
Query: 541 ARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNAL 600
ARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNAL
Sbjct: 541 ARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNAL 600
Query: 601 VELQTQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE 642
VELQTQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE
Sbjct: 601 VELQTQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE 642
>gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1
[Homo sapiens]
Length = 684
Score = 1255 bits (3247), Expect = 0.0
Identities = 642/684 (93%), Positives = 642/684 (93%), Gaps = 42/684 (6%)
Query: 1 MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTA----------------------- 37
MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTA
Sbjct: 1 MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYED 60
Query: 38 -------------------RLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL 78
RLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL
Sbjct: 61 LKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL 120
Query: 79 EQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPG 138
EQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPG
Sbjct: 121 EQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPG 180
Query: 139 VSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTIQASEEQSSTPAPVKKSGK 198
VSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTIQASEEQSSTPAPVKKSGK
Sbjct: 181 VSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTIQASEEQSSTPAPVKKSGK 240
Query: 199 LRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESK 258
LRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESK
Sbjct: 241 LRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESK 300
Query: 259 KAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAA 318
KAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAA
Sbjct: 301 KAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAA 360
Query: 319 QADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQE 378
QADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQE
Sbjct: 361 QADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQE 420
Query: 379 ITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPP 438
ITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPP
Sbjct: 421 ITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPP 480
Query: 439 QRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEP 498
QRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEP
Sbjct: 481 QRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEP 540
Query: 499 VDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFPV 558
VDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFPV
Sbjct: 541 VDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFPV 600
Query: 559 LLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFK 618
LLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFK
Sbjct: 601 LLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFK 660
Query: 619 ELGRFMLRYGGSTIAAGVVTEIKE 642
ELGRFMLRYGGSTIAAGVVTEIKE
Sbjct: 661 ELGRFMLRYGGSTIAAGVVTEIKE 684
>gi|46094014 peptide chain release factor 3 [Homo sapiens]
Length = 628
Score = 347 bits (890), Expect = 2e-95
Identities = 197/511 (38%), Positives = 296/511 (57%), Gaps = 18/511 (3%)
Query: 141 SEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTIQASEEQSSTPAPVKKSGKLR 200
S E +S T + P+ + LE + + + + S P ++SG+
Sbjct: 120 SLEGSNSAVTMELSEPVVENGEVEMALEESWEHSKEVSEAEPGGGSSGDSGPPEESGQ-- 177
Query: 201 QQIDVKAELEKRQG--------GKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHK 252
+ ++ K E+ K + K+ +N+V IGHVDAGKST+ G +++L G ++KRT+ K
Sbjct: 178 EMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDKRTLEK 237
Query: 253 YEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPN 312
YE+E+K+ + ++ +W LD EER++G T++VG FET K T++DAPGHK F+PN
Sbjct: 238 YEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAPGHKSFVPN 297
Query: 313 MITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQ--VN 370
MI GA+QAD+AVLV+ A +GEFE GFE GGQTREH +L ++ GV L V +NKMD VN
Sbjct: 298 MIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVN 357
Query: 371 WQQERFQEITGKLGHFLKQAGFK-ESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLL 429
W ER++E KL FLK+ GF + D+ F+P SGL+G N+ + S+ WY GL +
Sbjct: 358 WSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANI---KEQSDFCPWYTGLPFI 414
Query: 430 EQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTV 489
+D+ RSID P RL + D +KD G+ + GK+E+G I G +L+ MP V
Sbjct: 415 PYLDNLPNFNRSIDGPIRLPIVDKYKDMGT--VVLGKLESGSIFKGQQLVMMPNKHNVEV 472
Query: 490 KGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIE 549
GI D D+ A G+++ + L G++ +I G I C P + F +I+I +
Sbjct: 473 LGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGRTFDVQIVIIEHK 532
Query: 550 IPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPI 609
I G+ +LH T E I LIS+++K +GE +K +P+F+ + Q + L+T I
Sbjct: 533 SIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTI 592
Query: 610 ALELYKDFKELGRFMLRYGGSTIAAGVVTEI 640
LE +KDF ++GRF LR G TIA G V ++
Sbjct: 593 CLETFKDFPQMGRFTLRDEGKTIAIGKVLKL 623
>gi|194018522 G1 to S phase transition 1 isoform 3 [Homo sapiens]
Length = 499
Score = 344 bits (883), Expect = 1e-94
Identities = 196/503 (38%), Positives = 291/503 (57%), Gaps = 22/503 (4%)
Query: 143 ENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTI--QASEEQSSTPAPVKKSGKLR 200
ENG + +P++ ++ I+ ++ + PP + EE+ P P
Sbjct: 9 ENGETEMSPEESWEHKEEISEAEPGGGSLGDGRPPEESAHEMMEEEEEIPKP-------- 60
Query: 201 QQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKA 260
+ + K K+ +N+V IGHVDAGKST+ G ++YL G ++KRT+ KYE+E+K+
Sbjct: 61 KSVVAPPGAPK----KEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEK 116
Query: 261 GKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQA 320
+ ++ +W LD EER++G T++VG FET K T++DAPGHK F+PNMI GA+QA
Sbjct: 117 NRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQA 176
Query: 321 DVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQ--VNWQQERFQE 378
D+AVLV+ A +GEFE GFE GGQTREH +L ++ GV L V +NKMD VNW ER++E
Sbjct: 177 DLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEE 236
Query: 379 ITGKLGHFLKQAGFK-ESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKP 437
KL FLK+ GF + D+ F+P SGL+G NL + S+ WY GL + +D+
Sbjct: 237 CKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANL---KEQSDFCPWYIGLPFIPYLDNLPN 293
Query: 438 PQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDE 497
RS+D P RL + D +KD G+ + GK+E+G I G +L+ MP V GI D
Sbjct: 294 FNRSVDGPIRLPIVDKYKDMGT--VVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDV 351
Query: 498 PVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFP 557
D A G+++ + L G++ +I G I C P + F A+I+I + I G+
Sbjct: 352 ETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEHKSIICPGYN 411
Query: 558 VLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDF 617
+LH T E I LI +++K +GE +K +P+F+ + Q + L+T I LE +KDF
Sbjct: 412 AVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDF 471
Query: 618 KELGRFMLRYGGSTIAAGVVTEI 640
++GRF LR G TIA G V ++
Sbjct: 472 PQMGRFTLRDEGKTIAIGKVLKL 494
>gi|194097354 G1 to S phase transition 1 isoform 2 [Homo sapiens]
Length = 636
Score = 344 bits (883), Expect = 1e-94
Identities = 196/503 (38%), Positives = 291/503 (57%), Gaps = 22/503 (4%)
Query: 143 ENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTI--QASEEQSSTPAPVKKSGKLR 200
ENG + +P++ ++ I+ ++ + PP + EE+ P P
Sbjct: 146 ENGETEMSPEESWEHKEEISEAEPGGGSLGDGRPPEESAHEMMEEEEEIPKP-------- 197
Query: 201 QQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKA 260
+ + K K+ +N+V IGHVDAGKST+ G ++YL G ++KRT+ KYE+E+K+
Sbjct: 198 KSVVAPPGAPK----KEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEK 253
Query: 261 GKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQA 320
+ ++ +W LD EER++G T++VG FET K T++DAPGHK F+PNMI GA+QA
Sbjct: 254 NRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQA 313
Query: 321 DVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQ--VNWQQERFQE 378
D+AVLV+ A +GEFE GFE GGQTREH +L ++ GV L V +NKMD VNW ER++E
Sbjct: 314 DLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEE 373
Query: 379 ITGKLGHFLKQAGFK-ESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKP 437
KL FLK+ GF + D+ F+P SGL+G NL + S+ WY GL + +D+
Sbjct: 374 CKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANL---KEQSDFCPWYIGLPFIPYLDNLPN 430
Query: 438 PQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDE 497
RS+D P RL + D +KD G+ + GK+E+G I G +L+ MP V GI D
Sbjct: 431 FNRSVDGPIRLPIVDKYKDMGT--VVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDV 488
Query: 498 PVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFP 557
D A G+++ + L G++ +I G I C P + F A+I+I + I G+
Sbjct: 489 ETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEHKSIICPGYN 548
Query: 558 VLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDF 617
+LH T E I LI +++K +GE +K +P+F+ + Q + L+T I LE +KDF
Sbjct: 549 AVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDF 608
Query: 618 KELGRFMLRYGGSTIAAGVVTEI 640
++GRF LR G TIA G V ++
Sbjct: 609 PQMGRFTLRDEGKTIAIGKVLKL 631
>gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens]
Length = 637
Score = 344 bits (883), Expect = 1e-94
Identities = 196/503 (38%), Positives = 291/503 (57%), Gaps = 22/503 (4%)
Query: 143 ENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTI--QASEEQSSTPAPVKKSGKLR 200
ENG + +P++ ++ I+ ++ + PP + EE+ P P
Sbjct: 147 ENGETEMSPEESWEHKEEISEAEPGGGSLGDGRPPEESAHEMMEEEEEIPKP-------- 198
Query: 201 QQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKA 260
+ + K K+ +N+V IGHVDAGKST+ G ++YL G ++KRT+ KYE+E+K+
Sbjct: 199 KSVVAPPGAPK----KEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEK 254
Query: 261 GKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQA 320
+ ++ +W LD EER++G T++VG FET K T++DAPGHK F+PNMI GA+QA
Sbjct: 255 NRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQA 314
Query: 321 DVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQ--VNWQQERFQE 378
D+AVLV+ A +GEFE GFE GGQTREH +L ++ GV L V +NKMD VNW ER++E
Sbjct: 315 DLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEE 374
Query: 379 ITGKLGHFLKQAGFK-ESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKP 437
KL FLK+ GF + D+ F+P SGL+G NL + S+ WY GL + +D+
Sbjct: 375 CKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANL---KEQSDFCPWYIGLPFIPYLDNLPN 431
Query: 438 PQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDE 497
RS+D P RL + D +KD G+ + GK+E+G I G +L+ MP V GI D
Sbjct: 432 FNRSVDGPIRLPIVDKYKDMGT--VVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDV 489
Query: 498 PVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFP 557
D A G+++ + L G++ +I G I C P + F A+I+I + I G+
Sbjct: 490 ETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEHKSIICPGYN 549
Query: 558 VLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDF 617
+LH T E I LI +++K +GE +K +P+F+ + Q + L+T I LE +KDF
Sbjct: 550 AVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDF 609
Query: 618 KELGRFMLRYGGSTIAAGVVTEI 640
++GRF LR G TIA G V ++
Sbjct: 610 PQMGRFTLRDEGKTIAIGKVLKL 632
>gi|4503471 eukaryotic translation elongation factor 1 alpha 1 [Homo
sapiens]
Length = 462
Score = 321 bits (823), Expect = 1e-87
Identities = 173/437 (39%), Positives = 255/437 (58%), Gaps = 12/437 (2%)
Query: 216 KQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETG 275
K +N+VVIGHVD+GKST GH++Y G I+KRT+ K+E+E+ + GK SF YAWVLD+
Sbjct: 5 KTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK 64
Query: 276 EERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFE 335
ERERG+T+D+ + KFET+ +T++DAPGH+DFI NMITG +QAD AVL+V A GEFE
Sbjct: 65 AERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFE 124
Query: 336 AGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVN--WQQERFQEITGKLGHFLKQAGFK 393
AG GQTREH LL +LGV QL V VNKMD + Q+R++EI ++ ++K+ G+
Sbjct: 125 AGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYN 184
Query: 394 ESDVGFIPTSGLSGENLITRSQSSELTKWYK---------GLCLLEQIDSFKPPQRSIDK 444
V F+P SG +G+N++ S + K +K G LLE +D PP R DK
Sbjct: 185 PDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTRPTDK 244
Query: 445 PFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEPVDWAAA 504
P RL + DV+K G G G++E G ++ G + P N T VK + +H E + A
Sbjct: 245 PLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALP 304
Query: 505 GDHVSLTLVGMDIIKINVGCIFCGPK-VPIKACTRFRARILIFNIEIPITKGFPVLLHYQ 563
GD+V + + + + G + K P F A+++I N I+ G+ +L
Sbjct: 305 GDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCH 364
Query: 564 TVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFKELGRF 623
T L +++ +G+ + PKFL G A+V++ +P+ +E + D+ LGRF
Sbjct: 365 TAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRF 424
Query: 624 MLRYGGSTIAAGVVTEI 640
+R T+A GV+ +
Sbjct: 425 AVRDMRQTVAVGVIKAV 441
>gi|4503475 eukaryotic translation elongation factor 1 alpha 2 [Homo
sapiens]
Length = 463
Score = 321 bits (822), Expect = 1e-87
Identities = 173/440 (39%), Positives = 259/440 (58%), Gaps = 14/440 (3%)
Query: 216 KQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETG 275
K +N+VVIGHVD+GKST GH++Y G I+KRT+ K+E+E+ + GK SF YAWVLD+
Sbjct: 5 KTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK 64
Query: 276 EERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFE 335
ERERG+T+D+ + KFETT IT++DAPGH+DFI NMITG +QAD AVL+V A GEFE
Sbjct: 65 AERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFE 124
Query: 336 AGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVN--WQQERFQEITGKLGHFLKQAGFK 393
AG GQTREH LL +LGV QL V VNKMD + ++R+ EI ++ ++K+ G+
Sbjct: 125 AGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYN 184
Query: 394 ESDVGFIPTSGLSGENLITRSQSSELTKWYK---------GLCLLEQIDSFKPPQRSIDK 444
+ V F+P SG G+N++ S + K +K G+ LLE +D+ PP R DK
Sbjct: 185 PATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDK 244
Query: 445 PFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEPVDWAAA 504
P RL + DV+K G G G++E G ++ G + P N T VK + +H E + A
Sbjct: 245 PLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALP 304
Query: 505 GDHVSLTLVGMDIIKINVGCIFCGPKV--PIKACTRFRARILIFNIEIPITKGFPVLLHY 562
GD+V + + + I G + CG P + +F ++++I N I+ G+ ++
Sbjct: 305 GDNVGFNVKNVSVKDIRRGNV-CGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDC 363
Query: 563 QTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFKELGR 622
T L +++ +G+ + PK L G A+VE+ +P+ +E + + LGR
Sbjct: 364 HTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGR 423
Query: 623 FMLRYGGSTIAAGVVTEIKE 642
F +R T+A GV+ +++
Sbjct: 424 FAVRDMRQTVAVGVIKNVEK 443
>gi|239757543 PREDICTED: similar to eukaryotic translation
elongation factor 1 alpha 2 [Homo sapiens]
Length = 444
Score = 270 bits (689), Expect = 4e-72
Identities = 156/425 (36%), Positives = 235/425 (55%), Gaps = 32/425 (7%)
Query: 216 KQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETG 275
K +N+VVIGHVD+GKST GH++Y G I+KRT+ K+E+E+ + GK SF YAWVLD+
Sbjct: 5 KTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK 64
Query: 276 EERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFE 335
ERERG+T+D+ + KFETT IT++DAPGH+DFI NMITG +QAD AVL+V A GEFE
Sbjct: 65 AERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFE 124
Query: 336 AGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVN--WQQERFQEITGKLGHFLKQAGFK 393
AG GQTREH LL +LGV QL V VNKMD + ++R+ EI ++ ++K+ G+
Sbjct: 125 AGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYN 184
Query: 394 ESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKP-FRLCV-- 450
+ V F+P SG G+N++ S + W+KG +K ++ + RLC
Sbjct: 185 PATVPFVPISGWHGDNMLEPSPNMP---WFKG---------WKVERKEGNASGXRLCPRI 232
Query: 451 ------------SDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEP 498
S G G G++E G ++ G + P N T VK + +H E
Sbjct: 233 SCPSIPSGPTFPSHPLPSAGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEA 292
Query: 499 VDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKV--PIKACTRFRARILIFNIEIPITKGF 556
+ A GD+V + + + I G + CG P + +F ++++I N I+ G+
Sbjct: 293 LSEALPGDNVGFNVKNVSVKDIRRGNV-CGDSKSDPPQEAAQFTSQVIILNHPGQISAGY 351
Query: 557 PVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKD 616
++ T L +++ +G+ + PK L G A+VE+ +P+ +E +
Sbjct: 352 SPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQ 411
Query: 617 FKELG 621
+ LG
Sbjct: 412 YPPLG 416
>gi|223633995 Hsp70 subfamily B suppressor 1-like protein isoform 3
[Homo sapiens]
Length = 632
Score = 187 bits (474), Expect = 3e-47
Identities = 102/144 (70%), Positives = 102/144 (70%), Gaps = 42/144 (29%)
Query: 1 MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTA----------------------- 37
MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTA
Sbjct: 1 MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYED 60
Query: 38 -------------------RLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL 78
RLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL
Sbjct: 61 LKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL 120
Query: 79 EQDRVQSLKDKNEATVSTGKIAKG 102
EQDRVQSLKDKNEATVSTGKIAKG
Sbjct: 121 EQDRVQSLKDKNEATVSTGKIAKG 144
>gi|34147630 Tu translation elongation factor, mitochondrial
precursor [Homo sapiens]
Length = 455
Score = 142 bits (357), Expect = 1e-33
Identities = 123/426 (28%), Positives = 188/426 (44%), Gaps = 46/426 (10%)
Query: 216 KQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETG 275
K +N+ IGHVD GK+TL + +L KYE+ +D
Sbjct: 58 KPHVNVGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEE---------------IDNAP 102
Query: 276 EERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFE 335
EER RG+T++ ++ T + D PGH D++ NMITG A D +LVV A+ G
Sbjct: 103 EERARGITINAAHVEYSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMP 162
Query: 336 AGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKES 395
QTREH LL R +GV + V VNK D V E + + ++ L + G+K
Sbjct: 163 -------QTREHLLLARQIGVEHVVVYVNKADAVQ-DSEMVELVELEIRELLTEFGYKGE 214
Query: 396 DVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKP-PQRSIDKPFRLCVSDVF 454
+ I S L L R L K LL+ +D++ P P R ++KPF L V V+
Sbjct: 215 ETPVIVGSALCA--LEGRDPELGLKSVQK---LLDAVDTYIPVPARDLEKPFLLPVEAVY 269
Query: 455 KDQGSGFCITGKIEAGYIQTGD--RLLAMPPNETCTVKGITLHDEPVDWAAAGDHVSLTL 512
G G +TG +E G ++ GD LL N V GI + + ++ A AGD++ +
Sbjct: 270 SVPGRGTVVTGTLERGILKKGDECELLGHSKNIRTVVTGIEMFHKSLERAEAGDNLGALV 329
Query: 513 VGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFPVLLHYQTVSEPAVIK 572
G+ + G + P IK + A++ I + E + P + H+ V
Sbjct: 330 RGLKREDLRRGLVMVKPG-SIKPHQKVEAQVYILSKE-EGGRHKPFVSHFMPVMFSLTWD 387
Query: 573 RLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFKELGRFMLRYGGSTI 632
+ + + + G++ L ++P+ LE + RF LR G TI
Sbjct: 388 MACRI-------ILPPEKELAMPGEDLKFNLILRQPMILEKGQ------RFTLRDGNRTI 434
Query: 633 AAGVVT 638
G+VT
Sbjct: 435 GTGLVT 440
>gi|82546879 GTP binding protein 1 [Homo sapiens]
Length = 669
Score = 82.4 bits (202), Expect = 1e-15
Identities = 102/396 (25%), Positives = 160/396 (40%), Gaps = 53/396 (13%)
Query: 209 LEKRQGGKQLLNL--VVIGHVDAGKSTLMGHMLYLLGNIN--------KRTMHKYEQESK 258
+ KR G L + V+G+VDAGKSTL+G + + G ++ K HK+E ES
Sbjct: 149 VRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTH--GELDNGRGFARQKLFRHKHEIESG 206
Query: 259 KAGKASFAYAWVLDETGEERERGVTM-------DVGMTKF-ETTTKVITLMDAPGHKDFI 310
+ D G + E V + TK E +TKVIT +D GH+ ++
Sbjct: 207 RTSSVGN------DILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYL 260
Query: 311 PNMITGAAQ--ADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQ 368
+ G D +L+V ++ G G T+EH L +L V + V V K+D
Sbjct: 261 KTTVFGMTGHLPDFCMLMVGSNAGIV-------GMTKEHLGLALALNVP-VFVVVTKIDM 312
Query: 369 VNWQQERFQEITGKLGHFLKQAGFKE-------SDVGFIPTSGLSGENLITRSQSSELTK 421
QE L LK G ++ D + S S E + Q S +T
Sbjct: 313 C--PANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTG 370
Query: 422 WYKGLCLLEQIDSFKPPQRSI--DKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLL 479
+ L LL+ + P+ S ++P + D + G G ++G G I+ D LL
Sbjct: 371 --ENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLL 428
Query: 480 AMPPNE----TCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKA 535
P + VK I PV G S L + I G + P++ +A
Sbjct: 429 LGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQA 488
Query: 536 CTRFRARILIFNIEIPITKGFPVLLHYQTVSEPAVI 571
F A IL+ + I+ + ++H ++ + A I
Sbjct: 489 SWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATI 524
>gi|54607086 eukaryotic elongation factor,
selenocysteine-tRNA-specific [Homo sapiens]
Length = 596
Score = 79.0 bits (193), Expect = 1e-14
Identities = 82/346 (23%), Positives = 141/346 (40%), Gaps = 70/346 (20%)
Query: 214 GGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDE 273
G + +N+ V+GH+D+GK+ L + S A A+F D+
Sbjct: 3 GRRVNVNVGVLGHIDSGKTALARAL------------------STTASTAAF------DK 38
Query: 274 TGEERERGVTMDVGMTKFETTTKV-------------------------ITLMDAPGHKD 308
+ RERG+T+D+G + F +TL+D PGH
Sbjct: 39 QPQSRERGITLDLGFSCFSVPLPARLRSSLPEFQAAPEAEPEPGEPLLQVTLVDCPGHAS 98
Query: 309 FIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQ 368
I +I GA D+ +LV+D ++G E L++ + +L V +NK+D
Sbjct: 99 LIRTIIGGAQIIDLMMLVIDVTKGMQTQSAEC--------LVIGQIACQKLVVVLNKIDL 150
Query: 369 V--NWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGL 426
+ +Q ++T K+ L+ F+ + + IP + G + T+ +G+
Sbjct: 151 LPEGKRQAAIDKMTKKMQKTLENTKFRGAPI--IPVAAKPG------GPEAPETEAPQGI 202
Query: 427 C-LLEQIDS-FKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPN 484
L+E + S P R PF + V F +G G +TG I +G I GD +
Sbjct: 203 PELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLGDSVEIPALK 262
Query: 485 ETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPK 530
VK + + P+ A GD + + + D + G + C P+
Sbjct: 263 VVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLV-CAPE 307
>gi|45593140 GTP binding protein 2 [Homo sapiens]
Length = 602
Score = 77.8 bits (190), Expect = 3e-14
Identities = 95/412 (23%), Positives = 172/412 (41%), Gaps = 61/412 (14%)
Query: 219 LNLVVIGHVDAGKSTLMGHMLY-LLGNINKRTM-----HKYEQESKKAGKASFAYAWVLD 272
L + V+G+VD+GKSTL+G + L N R H +E +S + SF
Sbjct: 173 LRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISF------- 225
Query: 273 ETGEERERGVTMDVGMTKF-----ETTTKVITLMDAPGHKDFIPNMITGAAQ--ADVAVL 325
E +G ++ ++ E+++K+IT +D GH ++ I G D A+L
Sbjct: 226 EILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHHKYLHTTIFGLTSYCPDCALL 285
Query: 326 VVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGH 385
+V A+ G G TREH L +L V + V+K+D + + +L
Sbjct: 286 LVSANTG-------IAGTTREHLGLALALKVP-FFIVVSKIDLC--AKTTVERTVRQLER 335
Query: 386 FLKQAGFKESDVGFIPTSGLSGENLITRSQ--------------------SSELTKWYKG 425
LKQ G + +P S ++ +T +Q S +L K +
Sbjct: 336 VLKQPGCHK-----VPMLVTSEDDAVTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVF-- 388
Query: 426 LCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNE 485
L +L + + K + + + V +++ G + G + +G + GD+L+ P ++
Sbjct: 389 LNILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGDQLVVGPTDD 448
Query: 486 TCTVK----GITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRA 541
C ++ I + AG +L L D + G + P++ C+ F A
Sbjct: 449 GCFLELRVCSIQRNRSACRVLRAGQAATLALGDFDRALLRKGMVMVSPEMNPTICSVFEA 508
Query: 542 RILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFL 593
I++ +GF V +H V + AV++++ + TGE + +FL
Sbjct: 509 EIVLLFHATTFRRGFQVTVHVGNVRQTAVVEKIHAKDKLRTGEKAVVRFRFL 560
>gi|157426893 GUF1 GTPase homolog [Homo sapiens]
Length = 669
Score = 75.1 bits (183), Expect = 2e-13
Identities = 101/427 (23%), Positives = 168/427 (39%), Gaps = 73/427 (17%)
Query: 179 TIQASEEQSSTPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHM 238
T+ A+ E +T + S + ++++D+ R + + N ++ HVD GKSTL +
Sbjct: 35 TLGAAPESWATDR-LYSSAEFKEKLDMS-----RFPVENIRNFSIVAHVDHGKSTLADRL 88
Query: 239 LYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKF----ETT 294
L L G I+K +K VLD+ ERERG+T+ E
Sbjct: 89 LELTGTIDKTKNNKQ----------------VLDKLQVERERGITVKAQTASLFYNCEGK 132
Query: 295 TKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSL 354
++ L+D PGH DF + + +LVVDA+ G QT + L
Sbjct: 133 QYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEG-------IQAQTVANFFLAFEA 185
Query: 355 GVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRS 414
++ + V +NK+D N ER + K+ F I S G N+ +
Sbjct: 186 QLSVIPV-INKIDLKNADPERVENQIEKV--------FDIPSDECIKISAKLGTNVESVL 236
Query: 415 QSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQT 474
Q+ I+ PP+ P R V D DQ G + G +
Sbjct: 237 QAI--------------IERIPPPKVHRKNPLRALVFDSTFDQYRGVIANVALFDGVVSK 282
Query: 475 GDRLLAMPPNETCTVKGITL---HDEPVDWAAAGDHVSLTLVGM-DIIKINVGCIFCGPK 530
GD++++ +T V + + +++P AG V + GM D+ + +G C K
Sbjct: 283 GDKIVSAHTQKTYEVNEVGVLNPNEQPTHKLYAG-QVGYLIAGMKDVTEAQIGDTLCLHK 341
Query: 531 VPIKACTRFR-ARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKK 589
P++ F+ A+ ++F P+ + SE +K I L + VT +
Sbjct: 342 QPVEPLPGFKSAKPMVFAGMYPLDQ-----------SEYNNLKSAIEKLTLNDSSVTVHR 390
Query: 590 PKFLTKG 596
L G
Sbjct: 391 DSSLALG 397
>gi|239752724 PREDICTED: similar to hCG1981735 [Homo sapiens]
Length = 155
Score = 68.6 bits (166), Expect = 2e-11
Identities = 47/139 (33%), Positives = 67/139 (48%), Gaps = 32/139 (23%)
Query: 305 GHKDFIPNMIT------------------GAAQA------------DVAVLVVDASRGEF 334
GH DFI NMIT G +QA D AVL+V + GE
Sbjct: 2 GHCDFIKNMITVTLQLPPGLPRPCCGDGQGVSQARSELGLPLSGREDCAVLIVASGVGEC 61
Query: 335 EAGFETGGQTREHGLLVRSLGVTQLAVAVNKMD--QVNWQQERFQEITGKLGHFLKQAGF 392
EAG Q EH LL +LG+ QL V VNKMD + + F+EI+ ++ ++K+ +
Sbjct: 62 EAGISKNKQICEHTLLAYTLGMKQLIVTVNKMDITEPPYSSTCFEEISKEVKAYIKKISY 121
Query: 393 KESDVGFIPTSGLSGENLI 411
+ F+P SG G+N++
Sbjct: 122 NSQTLPFVPISGWHGDNML 140
>gi|169162126 PREDICTED: similar to hCG1981735 [Homo sapiens]
Length = 155
Score = 68.6 bits (166), Expect = 2e-11
Identities = 47/139 (33%), Positives = 67/139 (48%), Gaps = 32/139 (23%)
Query: 305 GHKDFIPNMIT------------------GAAQA------------DVAVLVVDASRGEF 334
GH DFI NMIT G +QA D AVL+V + GE
Sbjct: 2 GHCDFIKNMITVTLQLPPGLPRPCCGDGQGVSQARSELGLPLSGQEDCAVLIVASGVGEC 61
Query: 335 EAGFETGGQTREHGLLVRSLGVTQLAVAVNKMD--QVNWQQERFQEITGKLGHFLKQAGF 392
EAG Q EH LL +LG+ QL V VNKMD + + F+EI+ ++ ++K+ +
Sbjct: 62 EAGISKNKQICEHTLLAYTLGMKQLIVTVNKMDITEPPYSSTCFEEISKEVKAYIKKISY 121
Query: 393 KESDVGFIPTSGLSGENLI 411
+ F+P SG G+N++
Sbjct: 122 NSQTLPFVPISGWHGDNML 140
>gi|169162824 PREDICTED: similar to hCG1981735 [Homo sapiens]
Length = 155
Score = 68.6 bits (166), Expect = 2e-11
Identities = 47/139 (33%), Positives = 67/139 (48%), Gaps = 32/139 (23%)
Query: 305 GHKDFIPNMIT------------------GAAQA------------DVAVLVVDASRGEF 334
GH DFI NMIT G +QA D AVL+V + GE
Sbjct: 2 GHCDFIKNMITVTLQLPPGLPRPCCGDGQGVSQARSELGLPLSGQEDCAVLIVASGVGEC 61
Query: 335 EAGFETGGQTREHGLLVRSLGVTQLAVAVNKMD--QVNWQQERFQEITGKLGHFLKQAGF 392
EAG Q EH LL +LG+ QL V VNKMD + + F+EI+ ++ ++K+ +
Sbjct: 62 EAGISKNKQICEHTLLAYTLGMKQLIVTVNKMDITEPPYSSTCFEEISKEVKAYIKKISY 121
Query: 393 KESDVGFIPTSGLSGENLI 411
+ F+P SG G+N++
Sbjct: 122 NSQTLPFVPISGWHGDNML 140
>gi|169217153 PREDICTED: similar to EEF1A1 protein [Homo sapiens]
Length = 105
Score = 67.4 bits (163), Expect = 4e-11
Identities = 34/86 (39%), Positives = 53/86 (61%), Gaps = 6/86 (6%)
Query: 216 KQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETG 275
K +++ VIGH D+GK T GH+ ++KRT+ +E+++ + GK F YAWVL +
Sbjct: 5 KAHISITVIGHQDSGKPTTNGHL------VDKRTIENFEKDAAEMGKGFFKYAWVLHKLK 58
Query: 276 EERERGVTMDVGMTKFETTTKVITLM 301
E E GVT+D+ KFET+ + L+
Sbjct: 59 AECECGVTIDISPWKFETSKQWTRLL 84
>gi|113430525 PREDICTED: similar to EEF1A1 protein [Homo sapiens]
Length = 105
Score = 67.4 bits (163), Expect = 4e-11
Identities = 34/86 (39%), Positives = 53/86 (61%), Gaps = 6/86 (6%)
Query: 216 KQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETG 275
K +++ VIGH D+GK T GH+ ++KRT+ +E+++ + GK F YAWVL +
Sbjct: 5 KAHISITVIGHQDSGKPTTNGHL------VDKRTIENFEKDAAEMGKGFFKYAWVLHKLK 58
Query: 276 EERERGVTMDVGMTKFETTTKVITLM 301
E E GVT+D+ KFET+ + L+
Sbjct: 59 AECECGVTIDISPWKFETSKQWTRLL 84
>gi|113429979 PREDICTED: similar to EEF1A1 protein [Homo sapiens]
Length = 105
Score = 67.4 bits (163), Expect = 4e-11
Identities = 34/86 (39%), Positives = 53/86 (61%), Gaps = 6/86 (6%)
Query: 216 KQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETG 275
K +++ VIGH D+GK T GH+ ++KRT+ +E+++ + GK F YAWVL +
Sbjct: 5 KAHISITVIGHQDSGKPTTNGHL------VDKRTIENFEKDAAEMGKGFFKYAWVLHKLK 58
Query: 276 EERERGVTMDVGMTKFETTTKVITLM 301
E E GVT+D+ KFET+ + L+
Sbjct: 59 AECECGVTIDISPWKFETSKQWTRLL 84
>gi|53729339 mitochondrial translational initiation factor 2
precursor [Homo sapiens]
Length = 727
Score = 57.8 bits (138), Expect = 3e-08
Identities = 64/261 (24%), Positives = 104/261 (39%), Gaps = 55/261 (21%)
Query: 221 LVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERER 280
+ ++GHVD GK+TL+ K K A ETG
Sbjct: 183 VTIMGHVDHGKTTLLD----------------------KFRKTQVAAV----ETG----- 211
Query: 281 GVTMDVGMTKFETTT-KVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFE 339
G+T +G + + IT +D PGH F GA D+ VLVV A G + E
Sbjct: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
Query: 340 TGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGF 399
+ ++ + +AVNK D+ E+ ++ + G DV
Sbjct: 272 SIQHAKD--------AQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYG---GDVQA 320
Query: 400 IPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGS 459
+P S L+G+NL+ ++++ + L E ++ P + P V + F D+G
Sbjct: 321 VPVSALTGDNLMALAEAT--------VALAEMLELKADP----NGPVEGTVIESFTDKGR 368
Query: 460 GFCITGKIEAGYIQTGDRLLA 480
G T I+ G ++ G L+A
Sbjct: 369 GLVTTAIIQRGTLRKGSVLVA 389
>gi|53729337 mitochondrial translational initiation factor 2
precursor [Homo sapiens]
Length = 727
Score = 57.8 bits (138), Expect = 3e-08
Identities = 64/261 (24%), Positives = 104/261 (39%), Gaps = 55/261 (21%)
Query: 221 LVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERER 280
+ ++GHVD GK+TL+ K K A ETG
Sbjct: 183 VTIMGHVDHGKTTLLD----------------------KFRKTQVAAV----ETG----- 211
Query: 281 GVTMDVGMTKFETTT-KVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFE 339
G+T +G + + IT +D PGH F GA D+ VLVV A G + E
Sbjct: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
Query: 340 TGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGF 399
+ ++ + +AVNK D+ E+ ++ + G DV
Sbjct: 272 SIQHAKD--------AQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYG---GDVQA 320
Query: 400 IPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGS 459
+P S L+G+NL+ ++++ + L E ++ P + P V + F D+G
Sbjct: 321 VPVSALTGDNLMALAEAT--------VALAEMLELKADP----NGPVEGTVIESFTDKGR 368
Query: 460 GFCITGKIEAGYIQTGDRLLA 480
G T I+ G ++ G L+A
Sbjct: 369 GLVTTAIIQRGTLRKGSVLVA 389
>gi|18390331 G elongation factor, mitochondrial 1 [Homo sapiens]
Length = 751
Score = 57.8 bits (138), Expect = 3e-08
Identities = 55/206 (26%), Positives = 87/206 (42%), Gaps = 25/206 (12%)
Query: 197 GKLRQQIDVKAELEKRQG---GKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKY 253
G R+Q++ KA G +++ N+ + H+D+GK+TL +LY G I K MH+
Sbjct: 22 GWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAK--MHEV 79
Query: 254 EQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNM 313
K V+D ER+RG+T+ T I ++D PGH DF +
Sbjct: 80 --------KGKDGVGAVMDSMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEV 131
Query: 314 ITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQ 373
D AVLV+ A G Q + + + +NK+D++
Sbjct: 132 ERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNV--------PFLTFINKLDRMGSNP 183
Query: 374 ER-FQEITGKLGHFLKQAGFKESDVG 398
R Q++ KL H A F + +G
Sbjct: 184 ARALQQMRSKLNH---NAAFMQIPMG 206
>gi|239756373 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 53.1 bits (126), Expect = 8e-07
Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 21/134 (15%)
Query: 203 IDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGK 262
+D +L+K + N+ V+ HVD GK+TL ++ G I+ S AGK
Sbjct: 137 LDKMIQLQKNTAN--IRNICVLAHVDRGKTTLADCLISSNGIIS----------SHLAGK 184
Query: 263 ASFAYAWVLDETGEERERGVTMDVGMTKFETTTK----VITLMDAPGHKDFIPNMITGAA 318
+ +D +E+ RG+TM T +I L+D+PGH DF ++ T
Sbjct: 185 LRY-----MDSREDEQIRGITMKSSAISLHYATGNEEYLINLIDSPGHMDFSSDVSTAVR 239
Query: 319 QADVAVLVVDASRG 332
D ++VVDA G
Sbjct: 240 ICDGCIIVVDAVEG 253
>gi|239750897 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 53.1 bits (126), Expect = 8e-07
Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 21/134 (15%)
Query: 203 IDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGK 262
+D +L+K + N+ V+ HVD GK+TL ++ G I+ S AGK
Sbjct: 137 LDKMIQLQKNTAN--IRNICVLAHVDRGKTTLADCLISSNGIIS----------SHLAGK 184
Query: 263 ASFAYAWVLDETGEERERGVTMDVGMTKFETTTK----VITLMDAPGHKDFIPNMITGAA 318
+ +D +E+ RG+TM T +I L+D+PGH DF ++ T
Sbjct: 185 LRY-----MDSREDEQIRGITMKSSAISLHYATGNEEYLINLIDSPGHMDFSSDVSTAVR 239
Query: 319 QADVAVLVVDASRG 332
D ++VVDA G
Sbjct: 240 ICDGCIIVVDAVEG 253
>gi|239745282 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 53.1 bits (126), Expect = 8e-07
Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 21/134 (15%)
Query: 203 IDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGK 262
+D +L+K + N+ V+ HVD GK+TL ++ G I+ S AGK
Sbjct: 137 LDKMIQLQKNTAN--IRNICVLAHVDRGKTTLADCLISSNGIIS----------SHLAGK 184
Query: 263 ASFAYAWVLDETGEERERGVTMDVGMTKFETTTK----VITLMDAPGHKDFIPNMITGAA 318
+ +D +E+ RG+TM T +I L+D+PGH DF ++ T
Sbjct: 185 LRY-----MDSREDEQIRGITMKSSAISLHYATGNEEYLINLIDSPGHMDFSSDVSTAVR 239
Query: 319 QADVAVLVVDASRG 332
D ++VVDA G
Sbjct: 240 ICDGCIIVVDAVEG 253
>gi|94966754 elongation factor Tu GTP binding domain containing 1
isoform 1 [Homo sapiens]
Length = 1120
Score = 53.1 bits (126), Expect = 8e-07
Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 21/134 (15%)
Query: 203 IDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGK 262
+D +L+K + N+ V+ HVD GK+TL ++ G I+ R AGK
Sbjct: 6 LDKMIQLQKNTAN--IRNICVLAHVDHGKTTLADCLISSNGIISSRL----------AGK 53
Query: 263 ASFAYAWVLDETGEERERGVTMDVGMTKFETTTK----VITLMDAPGHKDFIPNMITGAA 318
+ +D +E+ RG+TM T +I L+D+PGH DF + T
Sbjct: 54 LRY-----MDSREDEQIRGITMKSSAISLHYATGNEEYLINLIDSPGHVDFSSEVSTAVR 108
Query: 319 QADVAVLVVDASRG 332
D ++VVDA G
Sbjct: 109 ICDGCIIVVDAVEG 122
>gi|25306287 mitochondrial elongation factor G2 isoform 2 [Homo
sapiens]
Length = 732
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 13/116 (11%)
Query: 217 QLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGE 276
++ N+ ++ H+DAGK+T +LY Y ++ G V D +
Sbjct: 69 KIRNIGIMAHIDAGKTTTTERILY------------YSGYTRSLGDVDDGDT-VTDFMAQ 115
Query: 277 ERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRG 332
ERERG+T+ F+ + L+D PGH DF + D AV V DAS G
Sbjct: 116 ERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAG 171
>gi|25306283 mitochondrial elongation factor G2 isoform 3 [Homo
sapiens]
Length = 513
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 13/116 (11%)
Query: 217 QLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGE 276
++ N+ ++ H+DAGK+T +LY Y ++ G V D +
Sbjct: 69 KIRNIGIMAHIDAGKTTTTERILY------------YSGYTRSLGDVDDGDT-VTDFMAQ 115
Query: 277 ERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRG 332
ERERG+T+ F+ + L+D PGH DF + D AV V DAS G
Sbjct: 116 ERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAG 171
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,634,882
Number of Sequences: 37866
Number of extensions: 1038210
Number of successful extensions: 3451
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 3291
Number of HSP's gapped (non-prelim): 123
length of query: 642
length of database: 18,247,518
effective HSP length: 109
effective length of query: 533
effective length of database: 14,120,124
effective search space: 7526026092
effective search space used: 7526026092
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.