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Search of human proteins with 223029432
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223029432 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 1 [Homo sapiens]
(507 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223029432 solute carrier family 2 (facilitated glucose transp... 1000 0.0
gi|223029430 solute carrier family 2 (facilitated glucose transp... 733 0.0
gi|21361449 solute carrier family 2 (facilitated glucose transpo... 358 5e-99
gi|203098995 solute carrier family 2 (facilitated glucose transp... 164 2e-40
gi|4507011 glucose transporter 4 [Homo sapiens] 161 1e-39
gi|166795299 solute carrier family 2 (facilitated glucose transp... 160 2e-39
gi|4557851 solute carrier family 2 (facilitated glucose transpor... 152 5e-37
gi|13540547 solute carrier family 2 member 10 [Homo sapiens] 151 2e-36
gi|21553331 solute carrier family 2 (facilitated glucose transpo... 148 1e-35
gi|23592238 glucose transporter 14 [Homo sapiens] 142 5e-34
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ... 138 1e-32
gi|134053883 intestinal facilitative glucose transporter 7 [Homo... 138 1e-32
gi|5902090 solute carrier family 2 (facilitated glucose transpor... 137 2e-32
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ... 135 9e-32
gi|4507013 solute carrier family 2 (facilitated glucose/fructose... 134 1e-31
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi... 123 4e-28
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] 123 4e-28
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] 123 4e-28
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 66 7e-11
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 66 7e-11
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 65 2e-10
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 65 2e-10
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 64 3e-10
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens] 62 2e-09
gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 60 5e-09
gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens] 60 6e-09
gi|207447703 solute carrier family 2 (facilitated glucose/fructo... 59 8e-09
gi|213021148 SVOP-like isoform 1 [Homo sapiens] 56 9e-08
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 52 1e-06
gi|24308167 SV2 related protein [Homo sapiens] 51 2e-06
>gi|223029432 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 1 [Homo sapiens]
Length = 507
Score = 1000 bits (2586), Expect = 0.0
Identities = 507/507 (100%), Positives = 507/507 (100%)
Query: 1 MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS 60
MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS
Sbjct: 1 MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS 60
Query: 61 PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA 120
PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA
Sbjct: 61 PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA 120
Query: 121 AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG 180
AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG
Sbjct: 121 AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG 180
Query: 181 SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT 240
SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT
Sbjct: 181 SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT 240
Query: 241 DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS 300
DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS
Sbjct: 241 DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS 300
Query: 301 IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYI 360
IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYI
Sbjct: 301 IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYI 360
Query: 361 HFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLL 420
HFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLL
Sbjct: 361 HFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLL 420
Query: 421 MSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTG 480
MSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTG
Sbjct: 421 MSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTG 480
Query: 481 CCVPETKGRSLEQIESFFRTGRRSFLR 507
CCVPETKGRSLEQIESFFRTGRRSFLR
Sbjct: 481 CCVPETKGRSLEQIESFFRTGRRSFLR 507
>gi|223029430 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 2 [Homo sapiens]
Length = 445
Score = 733 bits (1891), Expect = 0.0
Identities = 407/507 (80%), Positives = 418/507 (82%), Gaps = 62/507 (12%)
Query: 1 MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS 60
MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS
Sbjct: 1 MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS 60
Query: 61 PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA 120
PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA
Sbjct: 61 PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA 120
Query: 121 AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG 180
AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG
Sbjct: 121 AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG 180
Query: 181 SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT 240
SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT
Sbjct: 181 SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT 240
Query: 241 DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS 300
DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS
Sbjct: 241 DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS 300
Query: 301 IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYI 360
IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVS G +
Sbjct: 301 IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVS-----------GYAV 349
Query: 361 HFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLL 420
+GP T L SE PL A G + + +LA+ L ++L
Sbjct: 350 GWGP------ITWLLMSE-----VLPLRA-RGVASGLCVLASWL-----------TAFVL 386
Query: 421 MSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTG 480
LP+ ++ F L F FF FAAICLVSLVFTG
Sbjct: 387 TKSFLPV---------------VSTFGLQVPF------------FF-FAAICLVSLVFTG 418
Query: 481 CCVPETKGRSLEQIESFFRTGRRSFLR 507
CCVPETKGRSLEQIESFFRTGRRSFLR
Sbjct: 419 CCVPETKGRSLEQIESFFRTGRRSFLR 445
>gi|21361449 solute carrier family 2 (facilitated glucose
transporter), member 8 [Homo sapiens]
Length = 477
Score = 358 bits (920), Expect = 5e-99
Identities = 209/485 (43%), Positives = 291/485 (60%), Gaps = 19/485 (3%)
Query: 17 PEKPPP---SPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTSPVIPALERSLDPD 73
PE+ P PG A G +RVFLA FAA LG SFG+AL Y+SP IP+L+R+ P
Sbjct: 6 PEETQPLLGPPGGSAPRG----RRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPA 61
Query: 74 LHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLW 133
L + ASWFG+V TLGAAAGG+ L D GRKLS++ +VP AG+A++ A +W
Sbjct: 62 PRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVW 121
Query: 134 MLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLPW 193
MLL GR LTG A G+ + PVY+SEIA P VRG LG+ QLM V G L Y G +L W
Sbjct: 122 MLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEW 181
Query: 194 RWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQD 253
RWLAV G P +M+LL+ FMP +PRFLL++ R +EA+ AL +L G++ WE I
Sbjct: 182 RWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQG--WEDPPIG- 238
Query: 254 NVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKD 313
QS + A R P + +P + + + QQL+G+ ++ Y ++IF+ A
Sbjct: 239 --AEQSFHL--ALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEE-AKFKDSSL 293
Query: 314 DAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTA 373
+ +VG +++L +AAL MD AGR++LL +S +M + G Y +S
Sbjct: 294 ASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHV 353
Query: 374 GLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVA 433
+ + AQP+ A G L + + + LFI G+AVGWGPI WLLMSE+ PL +GVA
Sbjct: 354 AISAPV---SAQPVDASVG-LAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVA 409
Query: 434 SGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQ 493
+G+CVL +WL AF++TK F ++ F+ +A C+ S++FT CVPETKG++LEQ
Sbjct: 410 TGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQ 469
Query: 494 IESFF 498
I + F
Sbjct: 470 ITAHF 474
>gi|203098995 solute carrier family 2 (facilitated glucose
transporter), member 13 [Homo sapiens]
Length = 648
Score = 164 bits (414), Expect = 2e-40
Identities = 142/543 (26%), Positives = 232/543 (42%), Gaps = 96/543 (17%)
Query: 38 VFLATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAA-GG 96
V++ + LG F FGY S + L+R L D + S T+GAAA
Sbjct: 81 VYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVS-----STVGAAAVSA 135
Query: 97 LSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVY 156
L+ LN + GR+ +I+ ++ AG A++A A+ LL GR + G G+ + +PVY
Sbjct: 136 LAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVY 195
Query: 157 VSEIAPPGVRGALGATPQLMAV----FGSLSLYALGLLLP--WRWLAVAGEAPVLIMILL 210
++E++PP +RG L L F S+ A L WR++ P +I
Sbjct: 196 IAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFG 255
Query: 211 LSFMPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAP 270
F+P SPR+L+ +G+ ++A R L+ +RG + E++ I++N+ + V A P
Sbjct: 256 FLFLPESPRWLIQKGQTQKARRILSQMRGNQT-IDEEYDSIKNNIEEEEKEVGSA---GP 311
Query: 271 HVCR-----PITVALL----MRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD------A 315
+CR P AL+ +++ QQL+GI I+ Y +I + V +DD A
Sbjct: 312 VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGV----EDDRLAIWLA 367
Query: 316 AIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLG----LYIHFGPR----PL 367
++ + L+ ++ GR+ L F S A A + L L PR P+
Sbjct: 368 SVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPI 427
Query: 368 SPN----------------------------------------STAGLESESWGDLAQPL 387
+P+ + A +WG
Sbjct: 428 APSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENET 487
Query: 388 A------------APAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASG 435
P Y + LL +L+++ +A G GP+ W + SE+ PL AR +
Sbjct: 488 KFKTEDIFWAYNFCPTPY-SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNA 546
Query: 436 LCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIE 495
+W+ +++ +FL FF +A V L+F C+PETKG+ LE+IE
Sbjct: 547 CSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIE 606
Query: 496 SFF 498
S F
Sbjct: 607 SLF 609
>gi|4507011 glucose transporter 4 [Homo sapiens]
Length = 509
Score = 161 bits (407), Expect = 1e-39
Identities = 141/487 (28%), Positives = 225/487 (46%), Gaps = 57/487 (11%)
Query: 40 LATFAAVLGNFSFGYALVYTSPVIPALERSLD---------------PDLHLTKSQASWF 84
LA F+AVLG+ FGY + + +E+S + P LT A
Sbjct: 26 LAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALSV 85
Query: 85 GSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA---GAHGLWMLLLGRTL 141
++F++G I++ LGRK +++ + V + G +LM A ML+LGR L
Sbjct: 86 -AIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFL 144
Query: 142 TGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LLP----WRW 195
G GLT+ +P+YV EIAP +RGALG QL V G L LGL LL W
Sbjct: 145 IGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPL 204
Query: 196 LAVAGEAPVLIMILLLSFMPNSPRFL-LSRGRDEEALRALAWLRGTDVDVHWEFEQIQDN 254
L P L+ ++LL F P SPR+L + + + A ++L L G DV +++D
Sbjct: 205 LLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGW-ADVSGVLAELKDE 263
Query: 255 VRR--QSSRVSWAEARAPHVCR-PITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPP 311
R+ + +S + R P+ +A++++L QQL+GI + Y SIF++ V P
Sbjct: 264 KRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPA 323
Query: 312 KDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNS 371
G V + L++ L ++ AGR+ L + A M + + + + R
Sbjct: 324 YATIG-AGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLER------ 376
Query: 372 TAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARG 431
PA ++ V ++A F+ + +G GPI W +++E+ R
Sbjct: 377 -----------------VPA--MSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRP 417
Query: 432 VASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSL 491
A + ++W + F++ F V G V F FA + L +FT VPET+GR+
Sbjct: 418 AAMAVAGFSNWTSNFIIGMGFQYVAEAMGPYV-FLLFAVLLLGFFIFTFLRVPETRGRTF 476
Query: 492 EQIESFF 498
+QI + F
Sbjct: 477 DQISAAF 483
>gi|166795299 solute carrier family 2 (facilitated glucose
transporter), member 1 [Homo sapiens]
Length = 492
Score = 160 bits (406), Expect = 2e-39
Identities = 142/495 (28%), Positives = 225/495 (45%), Gaps = 59/495 (11%)
Query: 37 RVFLATFAAVLGNFSFGYALVYTSPVIPALERSLDP------------DLHLTKSQASWF 84
R+ LA AVLG+ FGY + VI A ++ ++ + T W
Sbjct: 11 RLMLAVGGAVLGSLQFGY----NTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWS 66
Query: 85 GSV--FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAH---GLWMLLLGR 139
SV F++G G S + + GR+ S++ + + LM + ML+LGR
Sbjct: 67 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGR 126
Query: 140 TLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL------LLPW 193
+ G GLT +P+YV E++P +RGALG QL V G L GL W
Sbjct: 127 FIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLW 186
Query: 194 RWLAVAGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQ 252
L P L+ ++L F P SPRFLL +R + A L LRGT DV + ++++
Sbjct: 187 PLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGT-ADVTHDLQEMK 245
Query: 253 DNVRR--QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLL 309
+ R+ + +V+ E R+P +PI +A++++L QQL+GI + Y SIF+ V
Sbjct: 246 EESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQ 305
Query: 310 PPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSP 369
P G V +++ ++ AGR+ L + A M + + +
Sbjct: 306 PVYATIG-SGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTI----------- 353
Query: 370 NSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRA 429
+ A LE W YL++V + F+ + VG GPI W +++E+
Sbjct: 354 -ALALLEQLPW----------MSYLSIVAIFG---FVAFFEVGPGPIPWFIVAELFSQGP 399
Query: 430 RGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGR 489
R A + ++W + F++ F V G V F F + ++ +FT VPETKGR
Sbjct: 400 RPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYV-FIIFTVLLVLFFIFTYFKVPETKGR 458
Query: 490 SLEQIESFFRTGRRS 504
+ ++I S FR G S
Sbjct: 459 TFDEIASGFRQGGAS 473
>gi|4557851 solute carrier family 2 (facilitated glucose
transporter), member 2 [Homo sapiens]
Length = 524
Score = 152 bits (385), Expect = 5e-37
Identities = 130/427 (30%), Positives = 204/427 (47%), Gaps = 51/427 (11%)
Query: 93 AAGGLSAMI----LNDLLGRKLSIMFSAVPSAAGYALMAGAHGLW----MLLLGRTLTGF 144
A GG++A L D LGR +++ + + S G AL+ G L +++ GR+++G
Sbjct: 105 AVGGMTASFFGGWLGDTLGRIKAMLVANILSLVG-ALLMGFSKLGPSHILIIAGRSISGL 163
Query: 145 AGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLL------PWRWLAV 198
GL + +P+Y+ EIAP +RGALG QL V G L +GL W L
Sbjct: 164 YCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLG 223
Query: 199 AGEAPVLIMILLLSFMPNSPRFLLSRGRDE-EALRALAWLRGTDVDVHWEFEQIQDNVRR 257
++ LLL F P SPR+L + +E +A ++L LRG D DV + +++
Sbjct: 224 LSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYD-DVTKDINEMRKEREE 282
Query: 258 QSS--RVSWAEARAPHVCR-PITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD 314
SS +VS + R PI VAL++ + QQ +GI I Y SIF TA + P
Sbjct: 283 ASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIF-QTAGISKPVYA 341
Query: 315 AAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMF--AANLTLGLYIHFGPRPLSPNST 372
VGAV ++ ++ ++ AGR+ L + + MF A +++GL +
Sbjct: 342 TIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVL------------ 389
Query: 373 AGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGV 432
L SW ++ V ++A LF+ + +G GPI W +++E R
Sbjct: 390 --LNKFSW-------------MSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPA 434
Query: 433 ASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLE 492
A + ++W F++ F + G V FF FA + L +FT VPETKG+S E
Sbjct: 435 ALAIAAFSNWTCNFIVALCFQYIADFCGPYV-FFLFAGVLLAFTLFTFFKVPETKGKSFE 493
Query: 493 QIESFFR 499
+I + F+
Sbjct: 494 EIAAEFQ 500
>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
Length = 541
Score = 151 bits (381), Expect = 2e-36
Identities = 150/536 (27%), Positives = 223/536 (41%), Gaps = 102/536 (19%)
Query: 40 LATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSA 99
L ++LG +FGY L S + L+ D L+ + + LGA L
Sbjct: 10 LCASVSLLGGLTFGYELAVISGALLPLQL----DFGLSCLEQEFLVGSLLLGALLASLVG 65
Query: 100 MILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSE 159
L D GRK +I+ S + AG + A L L+LGR + GFA L++ +YVSE
Sbjct: 66 GFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSE 125
Query: 160 IAPPGVRGALGATPQLMAVFGSLSLYALGLLL---PWRWLAVAG--EAPVLIMILLLSFM 214
+ P RG L + + G L YAL L PW W + G AP ++ L L F+
Sbjct: 126 LVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFL 185
Query: 215 PNSPRFLLSRGRDEEAL-RALAWLRGTDVDV---------HWEFEQIQDNVRRQSSRVSW 264
P G DE A + L L+G + + + +DN+R ++
Sbjct: 186 P--------AGTDETATHKDLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRT----- 232
Query: 265 AEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVG--AVR 322
TV L + L QQLTG +L Y +IF S A VG AV+
Sbjct: 233 ------------TVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVK 280
Query: 323 LLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLY-----IHFGPRPLS-PNSTA--G 374
+ + L A +D AGR+ LL A+M + +GL + GP L+ PN+T G
Sbjct: 281 VAATLTAMGLVDRAGRRALLLAGCALMALSVSGIGLVSFAVPMDSGPSCLAVPNATGQTG 340
Query: 375 LESESW--------------GDLAQPLAAPA----------------------------- 391
L +S D +P+ + A
Sbjct: 341 LPGDSGLLQDSSLPPIPRTNEDQREPILSTAKKTKPHPRSGDPSAPPRLALSSALPGPPL 400
Query: 392 -----GYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAF 446
L LL M+F+ ++ G+GP+TWL++SE+ P+ RG A C +W
Sbjct: 401 PARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANL 460
Query: 447 VLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGR 502
++ SFL ++ T GL F + ++ L F VPETKG+SL +I+ F+ R
Sbjct: 461 FISLSFLDLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKRR 516
>gi|21553331 solute carrier family 2 (facilitated glucose
transporter), member 12 [Homo sapiens]
Length = 617
Score = 148 bits (373), Expect = 1e-35
Identities = 134/529 (25%), Positives = 227/529 (42%), Gaps = 82/529 (15%)
Query: 39 FLATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLS 98
FL++ A + GY L S + ++ L H + S +GA L+
Sbjct: 41 FLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCH----EQEMVVSSLVIGALLASLT 96
Query: 99 AMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVS 158
+L D GR+ +I+ S+ G ++ + +L++GR G + L++ VY++
Sbjct: 97 GGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIA 156
Query: 159 EIAPPGVRGALGATPQLMAVFGSLSLYA-----LGLLLPWRWLAVAGEAPVLIMILLLSF 213
EIAP RG L + +LM V G LS Y + W+++ ++ + + F
Sbjct: 157 EIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYF 216
Query: 214 MPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVC 273
+P SPRFL+ +G++ A + L LR D E I+ +++ + W R+
Sbjct: 217 LPPSPRFLVMKGQEGAASKVLGRLRALS-DTTEELTVIKSSLKDEYQYSFWDLFRSKDNM 275
Query: 274 RP-ITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAI-----VGAVRLLSVL 327
R I + L + Q+TG IL Y ++ S ++AA VG V+++S +
Sbjct: 276 RTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGF---QSNEAASLASTGVGVVKVISTI 332
Query: 328 IAALTMDLAGRKVLLFVSAAIMFAANLTLG---LYIH----------------------F 362
A L +D G K L + +++M A+ +T+G L IH +
Sbjct: 333 PATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIY 392
Query: 363 GPRPLSPNS-------------------------------------TAGLESESWGDLAQ 385
GP LS N+ AGL + +
Sbjct: 393 GPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTD 452
Query: 386 PLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTA 445
P PA +L + L + ++++ +++G GP+ WL++SE+ P RG A L +W
Sbjct: 453 PGDVPA-FLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGIN 511
Query: 446 FVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 494
+++ +FL V GL F + + L SL+F +PETKG SLEQI
Sbjct: 512 LLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQI 560
>gi|23592238 glucose transporter 14 [Homo sapiens]
Length = 520
Score = 142 bits (359), Expect = 5e-34
Identities = 130/484 (26%), Positives = 216/484 (44%), Gaps = 51/484 (10%)
Query: 38 VFLATFAAVLGNFSFGYAL-VYTSP---VIPALERSLDPDLHLTKSQA------SWFGSV 87
+ A A +G+F FGY V +P + + ++L + S+ S ++
Sbjct: 34 LIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAI 93
Query: 88 FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG---AHGLWMLLLGRTLTGF 144
F++G G S + + GR+ S++ + +A G LM A + ML+LGR + G
Sbjct: 94 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGL 153
Query: 145 AGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL--SLYALGLLLP----WRWLAV 198
GL +P+Y+ EI+P +RGA G QL V G L ++ L L+L W L
Sbjct: 154 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLG 213
Query: 199 AGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRR 257
P ++ L P SPRFLL +R ++E A R L L GT DV + ++++D R
Sbjct: 214 FTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQ-DVSQDIQEMKDESAR 272
Query: 258 --QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD 314
Q +V+ E R +PI ++++++L QQL+GI + Y IF V P
Sbjct: 273 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYAT 332
Query: 315 AAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTAG 374
+ G V + L++ ++ AGR+ L + M + + + + L N G
Sbjct: 333 IS-AGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSL------LLKNHYNG 385
Query: 375 LESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVAS 434
++ V + A ++F+ + +G GPI W +++E+ R A
Sbjct: 386 -------------------MSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAM 426
Query: 435 GLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 494
+ ++W + F++ F G V F F + L FT VPET+GR+ E I
Sbjct: 427 AVAGCSNWTSNFLVGLLFPSAAYYLGAYV-FIIFTGFLITFLAFTFFKVPETRGRTFEDI 485
Query: 495 ESFF 498
F
Sbjct: 486 TRAF 489
>gi|47933387 solute carrier family 2, member 9 protein isoform 1
[Homo sapiens]
Length = 540
Score = 138 bits (348), Expect = 1e-32
Identities = 142/530 (26%), Positives = 227/530 (42%), Gaps = 79/530 (14%)
Query: 21 PPSPG------DRARVGTLQNKR-------VFLATFAAVLGN-FSFGYALVYTSPVIPAL 66
PP PG D R G +R + +A+ A G+ F +GY L + P +
Sbjct: 26 PPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYI 85
Query: 67 E------------RSLDPD-LHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIM 113
+ R +DPD L L S S+F +G G L ++ +LGRK +++
Sbjct: 86 KAFYNESWERRHGRPIDPDTLTLLWSVTV---SIFAIGGLVGTLIVKMIGKVLGRKHTLL 142
Query: 114 FS---AVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALG 170
+ A+ +A A A ML++GR + G GG+ + +P+Y+SEI+P +RG+LG
Sbjct: 143 ANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLG 202
Query: 171 ATPQLMAVFGSLSLYALGL--LL----PWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSR 224
+ G + LGL LL W +L P ++ +L L F+P+SPR+LL
Sbjct: 203 QVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLE 262
Query: 225 GRDE-EALRALAWLRGTDVDVHWEFEQI--QDNVRRQSSRVSWAE-ARAPHVCRPITVAL 280
+E A++A G DV E E++ + V+R VS E RAP+V + +
Sbjct: 263 KHNEARAVKAFQTFLG-KADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVI 321
Query: 281 LMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAI---VGAVRLLSVLIAALTMDLAG 337
+ QL G+ I Y SIF + PP + G + L+ + + L ++ G
Sbjct: 322 VTMACYQLCGLNAIWFYTNSIFGKAGI--PPAKIPYVTLSTGGIETLAAVFSGLVIEHLG 379
Query: 338 RKVLLFVSAAIM--FAANLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLT 395
R+ LL +M F LT+ L + Q A YL+
Sbjct: 380 RRPLLIGGFGLMGLFFGTLTITLTL------------------------QDHAPWVPYLS 415
Query: 396 LVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPV 455
+V +LA I + G G I ++L E R A + +WL+ F + F P
Sbjct: 416 IVGILA---IIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLF-PF 471
Query: 456 VSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRSF 505
+ F FA IC+ ++ +PETK R+ +I F +++
Sbjct: 472 IQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAY 521
>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
sapiens]
Length = 512
Score = 138 bits (347), Expect = 1e-32
Identities = 134/511 (26%), Positives = 231/511 (45%), Gaps = 60/511 (11%)
Query: 20 PPPSPGDRARVGTLQNKRVFLATFAAVLGN-FSFGYAL-VYTSP--VIPALERSLDPDLH 75
PPP P +R G LQ + LAT +A G+ F +GY L V +P V + + H
Sbjct: 9 PPPIP---SREGRLQ-PTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERH 64
Query: 76 LTKSQA-------SWFGSVFTLGAAAGGLSAMILNDLLGRKLSIM----FSAVPSAA-GY 123
T S S+F LG G L +L D GRK +++ F+ +P+ G
Sbjct: 65 ATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGV 124
Query: 124 ALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL- 182
+ +A A L ++ R + G G++ + +P+Y+ E+AP +RG +G ++ + G
Sbjct: 125 SKVAKAFEL--IVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFL 182
Query: 183 -SLYALGLLL--PWRW---LAVAGEAPVLIMILLLSFMPNSPRF-LLSRGRDEEALRALA 235
+++L +L P W LA+ G P L+ +L L F P SPR+ L+ +G + A +AL
Sbjct: 183 AQIFSLQAILGNPAGWPVLLALTG-VPALLQLLTLPFFPESPRYSLIQKGDEATARQALR 241
Query: 236 WLRG-TDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLL-QQLTGITP 293
LRG TD++ E + + R +S A R +++++ + QQL+GI
Sbjct: 242 RLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINA 301
Query: 294 ILVYLQSIFDSTAVLLPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAA 352
I Y +I+ S V + G V ++ + +A+ ++ GR+ LL I +A
Sbjct: 302 INYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSA 361
Query: 353 NLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVG 412
L L + + F R L+ + ++ +I G+++G
Sbjct: 362 CLVLTVVLLFQNR-------------------------VPELSYLGIICVFAYIAGHSIG 396
Query: 413 WGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAIC 472
P+ ++ +E+ +R A + WLT F++ F + G F FA IC
Sbjct: 397 PSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIG-AYSFIIFAGIC 455
Query: 473 LVSLVFTGCCVPETKGRSLEQIESFFRTGRR 503
L++ ++ +PETKG++ +I F R
Sbjct: 456 LLTAIYIYVVIPETKGKTFVEINRIFAKRNR 486
>gi|5902090 solute carrier family 2 (facilitated glucose
transporter), member 3 [Homo sapiens]
Length = 496
Score = 137 bits (345), Expect = 2e-32
Identities = 131/490 (26%), Positives = 212/490 (43%), Gaps = 63/490 (12%)
Query: 38 VFLATFAAVLGNFSFGYALVYTSPVIPALERSLD--------------PDLHLTKSQASW 83
+ A A +G+F FGY + VI A E+ + P L S S
Sbjct: 10 LIFAITVATIGSFQFGY----NTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSL 65
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA---GAHGLWMLLLGRT 140
++F++G G S + + GR+ S++ + + G M A + ML+LGR
Sbjct: 66 SVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRL 125
Query: 141 LTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL--SLYALGLLLP----WR 194
+ G GL +P+Y+ EI+P +RGA G QL V G L ++ L +L W
Sbjct: 126 VIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWP 185
Query: 195 WLAVAGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQD 253
L P ++ L F P SPRFLL +R +E A + L L GT DV + ++++D
Sbjct: 186 LLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQ-DVSQDIQEMKD 244
Query: 254 NVRR--QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP 310
R Q +V+ E R +PI ++++++L QQL+GI + Y IF V P
Sbjct: 245 ESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP 304
Query: 311 PKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVS-AAIMFAANL-TLGLYIHFGPRPLS 368
G V + +++ ++ AGR+ L + + F + L T+ L L
Sbjct: 305 IYATIG-AGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLL-------LK 356
Query: 369 PNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLR 428
N ++ V + A ++F+ + +G GPI W +++E+
Sbjct: 357 DNYNG--------------------MSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQG 396
Query: 429 ARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKG 488
R A + ++W + F++ F G V F F + L FT VPET+G
Sbjct: 397 PRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYV-FIIFTGFLITFLAFTFFKVPETRG 455
Query: 489 RSLEQIESFF 498
R+ E I F
Sbjct: 456 RTFEDITRAF 465
>gi|47933389 solute carrier family 2, member 9 protein isoform 2
[Homo sapiens]
Length = 511
Score = 135 bits (340), Expect = 9e-32
Identities = 134/500 (26%), Positives = 218/500 (43%), Gaps = 66/500 (13%)
Query: 38 VFLATFAAVLGN-FSFGYALVYTSPVIPALE------------RSLDPD-LHLTKSQASW 83
+ +A+ A G+ F +GY L + P ++ R +DPD L L S
Sbjct: 27 LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTV- 85
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFS---AVPSAAGYALMAGAHGLWMLLLGRT 140
S+F +G G L ++ +LGRK +++ + A+ +A A A ML++GR
Sbjct: 86 --SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRF 143
Query: 141 LTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----PWR 194
+ G GG+ + +P+Y+SEI+P +RG+LG + G + LGL LL W
Sbjct: 144 IMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWP 203
Query: 195 WLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDE-EALRALAWLRGTDVDVHWEFEQI-- 251
+L P ++ +L L F+P+SPR+LL +E A++A G DV E E++
Sbjct: 204 YLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLG-KADVSQEVEEVLA 262
Query: 252 QDNVRRQSSRVSWAE-ARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP 310
+ V+R VS E RAP+V + ++ QL G+ I Y SIF + P
Sbjct: 263 ESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGI--P 320
Query: 311 PKDDAAI---VGAVRLLSVLIAALTMDLAGRKVLLFVSAAIM--FAANLTLGLYIHFGPR 365
P + G + L+ + + L ++ GR+ LL +M F LT+ L +
Sbjct: 321 PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTL----- 375
Query: 366 PLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVL 425
Q A YL++V +LA I + G G I ++L E
Sbjct: 376 -------------------QDHAPWVPYLSIVGILA---IIASFCSGPGGIPFILTGEFF 413
Query: 426 PLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPE 485
R A + +WL+ F + F P + F FA IC+ ++ +PE
Sbjct: 414 QQSQRPAAFIIAGTVNWLSNFAVGLLF-PFIQKSLDTYCFLVFATICITGAIYLYFVLPE 472
Query: 486 TKGRSLEQIESFFRTGRRSF 505
TK R+ +I F +++
Sbjct: 473 TKNRTYAEISQAFSKRNKAY 492
>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 1 [Homo sapiens]
Length = 501
Score = 134 bits (338), Expect = 1e-31
Identities = 120/430 (27%), Positives = 196/430 (45%), Gaps = 47/430 (10%)
Query: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG---AHGLWMLLLGRTLT 142
S+F G G L L + GRK +++F+ + S LM A ++++ R L
Sbjct: 76 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
Query: 143 GFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LLP----WRWL 196
G G+++ +P+Y+ E+AP +RGALG PQL G L GL LL W L
Sbjct: 136 GICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPIL 195
Query: 197 AVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEAL-RALAWLRGTDVDVHWEFEQI--QD 253
P + +LLL F P SPR+LL + +DE A +AL LRG D V E +I +D
Sbjct: 196 LGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWD-SVDREVAEIRQED 254
Query: 254 NVRRQSSRVSWAEARAPHVCRPITVALLMRL-LQQLTGITPILVYLQSIFDSTAVLLPPK 312
+ + +S + R +++++ + QQL+G+ I Y I+ S V P+
Sbjct: 255 EAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGV---PE 311
Query: 313 DDAAIV----GAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLS 368
+ V GAV ++ A ++L GR++LL + +I A L
Sbjct: 312 EHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVL------------ 359
Query: 369 PNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLR 428
TA L L ++ + ++ + +++G+A+G PI LL++E+
Sbjct: 360 ---TAAL----------ALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQS 406
Query: 429 ARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKG 488
+R A + WL+ F + F + G F FA ICL++ ++ VPETK
Sbjct: 407 SRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLG-PYSFIVFAVICLLTTIYIFLIVPETKA 465
Query: 489 RSLEQIESFF 498
++ +I F
Sbjct: 466 KTFIEINQIF 475
>gi|190684655 glucose transporter protein 10 isoform a [Homo
sapiens]
Length = 503
Score = 123 bits (308), Expect = 4e-28
Identities = 130/493 (26%), Positives = 217/493 (44%), Gaps = 71/493 (14%)
Query: 37 RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83
R+ L T A + G F FGY L + +P + E + + PD HL S
Sbjct: 18 RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 76
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138
S++ LG G L A L LGRK S++ + V SAA G++ AG+ M++LG
Sbjct: 77 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 134
Query: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192
R L G G++ P+Y+ E AP +RGA+ + + G + +GL LL
Sbjct: 135 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 194
Query: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251
W L + P + + L +P SPR+LL D EA L AL LRG+ D+ E E++
Sbjct: 195 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 253
Query: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308
++ + +R W + + R +T +++ +L G + Y S+F V
Sbjct: 254 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 313
Query: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPL 367
A I G+ LL+ +++ + ++ GR+VLL ++M
Sbjct: 314 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM------------------ 355
Query: 368 SPNSTAGLESESWGDL---AQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEV 424
WG + A L + + + + FI+ + +G +T +L +E+
Sbjct: 356 ----------TCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATEL 405
Query: 425 LPLRARGVASGLCVLASWLTAFVLTKSF---LPVVSTFGLQVPFFFFAAICLVSLVFTGC 481
AR A +C W+ ++ F + +S F L VPF +C+ ++TG
Sbjct: 406 FDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF-LYVPFL---GVCVCGAIYTGL 461
Query: 482 CVPETKGRSLEQI 494
+PETKG++ ++I
Sbjct: 462 FLPETKGKTFQEI 474
>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
Length = 496
Score = 123 bits (308), Expect = 4e-28
Identities = 130/493 (26%), Positives = 217/493 (44%), Gaps = 71/493 (14%)
Query: 37 RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83
R+ L T A + G F FGY L + +P + E + + PD HL S
Sbjct: 11 RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 69
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138
S++ LG G L A L LGRK S++ + V SAA G++ AG+ M++LG
Sbjct: 70 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 127
Query: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192
R L G G++ P+Y+ E AP +RGA+ + + G + +GL LL
Sbjct: 128 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 187
Query: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251
W L + P + + L +P SPR+LL D EA L AL LRG+ D+ E E++
Sbjct: 188 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 246
Query: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308
++ + +R W + + R +T +++ +L G + Y S+F V
Sbjct: 247 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 306
Query: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPL 367
A I G+ LL+ +++ + ++ GR+VLL ++M
Sbjct: 307 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM------------------ 348
Query: 368 SPNSTAGLESESWGDL---AQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEV 424
WG + A L + + + + FI+ + +G +T +L +E+
Sbjct: 349 ----------TCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATEL 398
Query: 425 LPLRARGVASGLCVLASWLTAFVLTKSF---LPVVSTFGLQVPFFFFAAICLVSLVFTGC 481
AR A +C W+ ++ F + +S F L VPF +C+ ++TG
Sbjct: 399 FDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF-LYVPFL---GVCVCGAIYTGL 454
Query: 482 CVPETKGRSLEQI 494
+PETKG++ ++I
Sbjct: 455 FLPETKGKTFQEI 467
>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
Length = 499
Score = 123 bits (308), Expect = 4e-28
Identities = 130/493 (26%), Positives = 217/493 (44%), Gaps = 71/493 (14%)
Query: 37 RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83
R+ L T A + G F FGY L + +P + E + + PD HL S
Sbjct: 14 RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 72
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138
S++ LG G L A L LGRK S++ + V SAA G++ AG+ M++LG
Sbjct: 73 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 130
Query: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192
R L G G++ P+Y+ E AP +RGA+ + + G + +GL LL
Sbjct: 131 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 190
Query: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251
W L + P + + L +P SPR+LL D EA L AL LRG+ D+ E E++
Sbjct: 191 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 249
Query: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308
++ + +R W + + R +T +++ +L G + Y S+F V
Sbjct: 250 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 309
Query: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPL 367
A I G+ LL+ +++ + ++ GR+VLL ++M
Sbjct: 310 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM------------------ 351
Query: 368 SPNSTAGLESESWGDL---AQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEV 424
WG + A L + + + + FI+ + +G +T +L +E+
Sbjct: 352 ----------TCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATEL 401
Query: 425 LPLRARGVASGLCVLASWLTAFVLTKSF---LPVVSTFGLQVPFFFFAAICLVSLVFTGC 481
AR A +C W+ ++ F + +S F L VPF +C+ ++TG
Sbjct: 402 FDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF-LYVPFL---GVCVCGAIYTGL 457
Query: 482 CVPETKGRSLEQI 494
+PETKG++ ++I
Sbjct: 458 FLPETKGKTFQEI 470
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 66.2 bits (160), Expect = 7e-11
Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTG 143
F S G G L D GRKL ++ + + +A LMA + +LL R L G
Sbjct: 151 FQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQG 210
Query: 144 FAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-WRWLAVAGEA 202
++E G R + Q+ G ++L L LP WRWL +A
Sbjct: 211 LVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSL 270
Query: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
P + +L +P SPR+LLS+ R+ EA++ +
Sbjct: 271 PTFLFLLYYWCVPESPRWLLSQKRNTEAIKIM 302
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 66.2 bits (160), Expect = 7e-11
Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTG 143
F S G G L D GRKL ++ + + +A LMA + +LL R L G
Sbjct: 151 FQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQG 210
Query: 144 FAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-WRWLAVAGEA 202
++E G R + Q+ G ++L L LP WRWL +A
Sbjct: 211 LVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSL 270
Query: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
P + +L +P SPR+LLS+ R+ EA++ +
Sbjct: 271 PTFLFLLYYWCVPESPRWLLSQKRNTEAIKIM 302
>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
sapiens]
Length = 548
Score = 64.7 bits (156), Expect = 2e-10
Identities = 106/422 (25%), Positives = 169/422 (40%), Gaps = 66/422 (15%)
Query: 88 FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA-G 146
F G G ++ L+D GR+ ++ + V + A + M + RTLTG A
Sbjct: 151 FFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALA 210
Query: 147 GLTAACIPVYVS--EIAPPGVRGALGATPQLMAVFGSLSLYALGLLL-PWRWLAVAGEAP 203
G T +P+ + ++ V G L +T G + L +G L+ WRWL +A P
Sbjct: 211 GFTIIVMPLELEWLDVEHRTVAGVLSST---FWTGGVMLLALVGYLIRDWRWLLLAVTLP 267
Query: 204 VLIMILLLSFMPNSPRFLLSRGRDEEALRAL---AWLRGTDVDVHWEFEQIQDNVRRQSS 260
IL L ++P S R+LL++G +EA R L A L G V +D+ +++
Sbjct: 268 CAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPV--------CEDSFSQEA- 318
Query: 261 RVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIF-------DSTAVLLPPKD 313
VS A V RP + L + + ++V+ F D + + L
Sbjct: 319 -VSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQ 377
Query: 314 DAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTA 373
+ GAV L S L+ L++ AGR+ + A LG + FG R L
Sbjct: 378 TQLLFGAVELPSKLLVYLSVRYAGRR---------LTQAGTLLGTALAFGTRLL-----V 423
Query: 374 GLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPIT--WLLMSEVLPLRARG 431
+ +SW +T+L +MG A T +L SE+ P R
Sbjct: 424 SSDMKSW--------------------STVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQ 463
Query: 432 VASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSL 491
GL L L + + L + L +P + I L++ T +PET+ L
Sbjct: 464 TGMGLTALVGRLGGSLAPLAAL--LDGVWLSLPKLTYGGIALLA-AGTALLLPETRQAQL 520
Query: 492 EQ 493
+
Sbjct: 521 PE 522
>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
sapiens]
Length = 546
Score = 64.7 bits (156), Expect = 2e-10
Identities = 106/422 (25%), Positives = 169/422 (40%), Gaps = 66/422 (15%)
Query: 88 FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA-G 146
F G G ++ L+D GR+ ++ + V + A + M + RTLTG A
Sbjct: 149 FFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALA 208
Query: 147 GLTAACIPVYVS--EIAPPGVRGALGATPQLMAVFGSLSLYALGLLL-PWRWLAVAGEAP 203
G T +P+ + ++ V G L +T G + L +G L+ WRWL +A P
Sbjct: 209 GFTIIVMPLELEWLDVEHRTVAGVLSST---FWTGGVMLLALVGYLIRDWRWLLLAVTLP 265
Query: 204 VLIMILLLSFMPNSPRFLLSRGRDEEALRAL---AWLRGTDVDVHWEFEQIQDNVRRQSS 260
IL L ++P S R+LL++G +EA R L A L G V +D+ +++
Sbjct: 266 CAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPV--------CEDSFSQEA- 316
Query: 261 RVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIF-------DSTAVLLPPKD 313
VS A V RP + L + + ++V+ F D + + L
Sbjct: 317 -VSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQ 375
Query: 314 DAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTA 373
+ GAV L S L+ L++ AGR+ + A LG + FG R L
Sbjct: 376 TQLLFGAVELPSKLLVYLSVRYAGRR---------LTQAGTLLGTALAFGTRLL-----V 421
Query: 374 GLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPIT--WLLMSEVLPLRARG 431
+ +SW +T+L +MG A T +L SE+ P R
Sbjct: 422 SSDMKSW--------------------STVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQ 461
Query: 432 VASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSL 491
GL L L + + L + L +P + I L++ T +PET+ L
Sbjct: 462 TGMGLTALVGRLGGSLAPLAAL--LDGVWLSLPKLTYGGIALLA-AGTALLLPETRQAQL 518
Query: 492 EQ 493
+
Sbjct: 519 PE 520
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 63.9 bits (154), Expect = 3e-10
Identities = 89/420 (21%), Positives = 168/420 (40%), Gaps = 57/420 (13%)
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTG 143
F S +G G +S + D GRKL ++ + + +AA LMA + +L+ R + G
Sbjct: 152 FQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQG 211
Query: 144 FAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-WRWLAVAGEA 202
+ ++E R +G Q+ G L L + LP WRWL
Sbjct: 212 LVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVAL 271
Query: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRA---LAWLRGTDVDVHWEFEQIQDNVRRQS 259
P +L +P SPR+L+S+ ++ EA+R +A G + + ++++ ++
Sbjct: 272 PNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPASLQRLRLEEETGKKL 331
Query: 260 SRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVG 319
+ R P + R T+ L+ +++++ D+ + D
Sbjct: 332 NPSFLDLVRTPQI-RKHTMILMYNWFTSSVLYQGLIMHMGLAGDNIYL------DFFYSA 384
Query: 320 AVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTAGLESES 379
V + + LT+D GR+ S + AA L ++I
Sbjct: 385 LVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLA-SVFI------------------- 424
Query: 380 WGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARG----VASG 435
G L + ++ + L MG + + I L+ +E+ P R + S
Sbjct: 425 -----------PGDLQWLKIIISCLGRMGITMAY-EIVCLVNAELYPTFIRNLGVHICSS 472
Query: 436 LCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVS--LVFTGCCVPETKGRSLEQ 493
+C + +T F++ + ++ L++P F + LV+ LV +PETKG++L +
Sbjct: 473 MCDIGGIITPFLVYR-----LTNIWLELPLMVFGVLGLVAGGLVL---LLPETKGKALPE 524
>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
Length = 727
Score = 61.6 bits (148), Expect = 2e-09
Identities = 50/200 (25%), Positives = 83/200 (41%), Gaps = 17/200 (8%)
Query: 69 SLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG 128
S + DL + S + W GS+ LG G L D +GRK S++ + L +
Sbjct: 178 SAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSF 237
Query: 129 AHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALG 188
G L R L+GF G + Y +E+ RG + + + G + A+
Sbjct: 238 VQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMA 297
Query: 189 -LLLP----------------WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEAL 231
++P WR + P + ++ L+FMP SPRFLL G+ +EA
Sbjct: 298 WAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAW 357
Query: 232 RALAWLRGTDVDVHWEFEQI 251
L + T++ + E++
Sbjct: 358 MILKLIHDTNMRARGQPEKV 377
>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
Length = 556
Score = 60.1 bits (144), Expect = 5e-09
Identities = 99/421 (23%), Positives = 165/421 (39%), Gaps = 65/421 (15%)
Query: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
++ LG G + D GR + + S + ++A A + ++ R L G
Sbjct: 159 AILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVF 218
Query: 146 GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-WRWLAVAGEAPV 204
G T V V+EI R +G Q+ G + L + +P W+ + +A P
Sbjct: 219 GKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPS 278
Query: 205 LIMILLLSFMPNSPRFLLSRGRDEEA---LRALAWLRGTDVDVHWEFEQIQDNVRRQSSR 261
+ +L +P SPR+L++R + ++A LR +A G + ++ + D + S
Sbjct: 279 FLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTD---EEVSN 335
Query: 262 VSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVGAV 321
S+ + R T+ L+ +++ L I + + D I G V
Sbjct: 336 PSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYI------DFFISGVV 389
Query: 322 RLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTAGLESESWG 381
L L+ LT++ GR++ S + A L P A L +
Sbjct: 390 ELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFL---------PEGIAWLRTT--- 437
Query: 382 DLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLP--LRARGVA--SGLC 437
TL L TM F I +L+ SE+ P LR GV+ SGLC
Sbjct: 438 -----------VATLGRLGITMAF---------EIVYLVNSELYPTTLRNFGVSLCSGLC 477
Query: 438 VLASWLTAFVLTKSFLPVVSTFGLQVPFFFF---AAIC--LVSLVFTGCCVPETKGRSLE 492
+ F+L + ++ L++P F A+IC LV L +PETKG +L
Sbjct: 478 DFGGIIAPFLLFR-----LAAVWLELPLIIFGILASICGGLVML------LPETKGIALP 526
Query: 493 Q 493
+
Sbjct: 527 E 527
>gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]
Length = 683
Score = 59.7 bits (143), Expect = 6e-09
Identities = 55/217 (25%), Positives = 87/217 (40%), Gaps = 21/217 (9%)
Query: 43 FAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMIL 102
F L + G + S +P+ E+ D+ L+ S+ G + LG AG L
Sbjct: 113 FVLGLALMADGVEVFVVSFALPSAEK----DMCLSSSKKGMLGMIVYLGMMAGAFILGGL 168
Query: 103 NDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAP 162
D LGRK + S +A+ +L + G L R ++G G + Y SE
Sbjct: 169 ADKLGRKRVLSMSLAVNASFASLSSFVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLS 228
Query: 163 PGVRGALGATPQLMAVFGSLSLYALGL-LLP----------------WRWLAVAGEAPVL 205
RG + + + G L A+ ++P WR + P
Sbjct: 229 REKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCT 288
Query: 206 IMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGTDV 242
+ ++ L FMP SPRFLL G+ +EA L + T++
Sbjct: 289 VSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNM 325
>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 2 [Homo sapiens]
Length = 244
Score = 59.3 bits (142), Expect = 8e-09
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Query: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG---AHGLWMLLLGRTLT 142
S+F G G L L + GRK +++F+ + S LM A ++++ R L
Sbjct: 76 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
Query: 143 GFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL 189
G G+++ +P+Y+ E+AP +RGALG PQL G L GL
Sbjct: 136 GICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGL 182
>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
Length = 492
Score = 55.8 bits (133), Expect = 9e-08
Identities = 94/413 (22%), Positives = 156/413 (37%), Gaps = 64/413 (15%)
Query: 123 YALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYV-----------------------SE 159
+ L+A +G W +LL L G L + P Y+ +E
Sbjct: 104 FGLLADRYGRWKILLISFLWGAYFSLLTSFAPSYIWFVFLRTMVGCGVSGHSQGLIIKTE 163
Query: 160 IAPPGVRGALGATPQLMAVFGSLSLYALG-LLLP---WRWLAVAGEAPVLIMILLLSFMP 215
P RG + Q+ + GSL + L +++P WRWL P +I+I+ F+P
Sbjct: 164 FLPTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTIGWRWLIRVASIPGIILIVAFKFIP 223
Query: 216 NSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRP 275
S RF +S G AL L + + V E + ++ + ++ +A+
Sbjct: 224 ESARFNVSTGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKYLRTTLQ 283
Query: 276 ITVALLMRLLQQLTGITPILVYLQSIFDSTAVL-----LPPKDDAAIV--GAVRLLSVLI 328
I V L GI+ Y I S +L K D+A+V G S
Sbjct: 284 IWVIWL--------GIS--FAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGESQSP 333
Query: 329 AALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTAGLESESW--GDLAQP 386
M + +S A N L I+F R LS + T G + + ++
Sbjct: 334 CYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTS 393
Query: 387 LAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRAR----GVASGLCVLASW 442
A G+L ++ L F Y + +EV P R G + LC + +
Sbjct: 394 SAGLIGFLFMLRALVAANFNTVY---------IYTAEVYPTTMRALGMGTSGSLCRIGAM 444
Query: 443 LTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIE 495
+ F+ V+ + + F+++C+V + ETKGR+L+QI+
Sbjct: 445 VAPFI-----SQVLMSASILGALCLFSSVCVVCAISAFTLPIETKGRALQQIK 492
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 52.4 bits (124), Expect = 1e-06
Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 3/151 (1%)
Query: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
S+F G GGL L+D GR+ + S + AA + A + + ++ R L GF
Sbjct: 127 SIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFG 186
Query: 146 -GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-WRWLAVAGEAP 203
G+T + + + V E P +R + FG L L +P WRWL + P
Sbjct: 187 ISGITLSTVILNV-EWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIP 245
Query: 204 VLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
+ L + P S R+L+ G+ +AL+ L
Sbjct: 246 FFVFFLSSWWTPESIRWLVLSGKSSKALKIL 276
>gi|24308167 SV2 related protein [Homo sapiens]
Length = 548
Score = 51.2 bits (121), Expect = 2e-06
Identities = 45/173 (26%), Positives = 73/173 (42%), Gaps = 9/173 (5%)
Query: 70 LDPDLHLTKSQASWFGSVFTLGAAAGGLSAMIL----NDLLGRKLSIMFSAVPSAAGYAL 125
L P LH SW ++ T G +S+ L +D GRK + S + + L
Sbjct: 107 LAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGIL 166
Query: 126 MAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLY 185
A A +L+ R L GF G + +Y +E P R ++ G++
Sbjct: 167 SAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKARAKCILLIEVFWAIGTVFEV 225
Query: 186 ALGLL----LPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
L + L WRWL + P+L+ +L ++P S R+ + G E+A+ L
Sbjct: 226 VLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATL 278
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.140 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,849,269
Number of Sequences: 37866
Number of extensions: 806392
Number of successful extensions: 3394
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 3238
Number of HSP's gapped (non-prelim): 105
length of query: 507
length of database: 18,247,518
effective HSP length: 107
effective length of query: 400
effective length of database: 14,195,856
effective search space: 5678342400
effective search space used: 5678342400
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.