Guide to the Human Genome
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Search of human proteins with 222537734

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222537734 hypothetical protein LOC349633 [Homo sapiens]
         (207 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222537734 hypothetical protein LOC349633 [Homo sapiens]            406   e-114
gi|31742482 arylsulfatase F precursor [Homo sapiens]                   31   0.85 
gi|84626580 hypothetical protein LOC80178 [Homo sapiens]               30   1.1  
gi|8051636 tRNA exportin [Homo sapiens]                                30   1.9  
gi|57634534 nucleoporin 205kDa [Homo sapiens]                          29   2.5  
gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens]      29   2.5  
gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens]      29   2.5  
gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens]      29   2.5  
gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens]      29   2.5  
gi|46409390 transmembrane protein 179 [Homo sapiens]                   29   3.2  
gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs...    28   5.5  
gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precurs...    28   5.5  
gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Hom...    28   7.2  
gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Hom...    28   7.2  
gi|14249428 leucine-rich repeats and calponin homology (CH) doma...    28   7.2  
gi|14670350 general transcription factor II, i isoform 1 [Homo s...    27   9.4  
gi|209571547 kelch repeat and BTB (POZ) domain containing 4 isof...    27   9.4  
gi|209693446 kelch repeat and BTB (POZ) domain containing 4 isof...    27   9.4  

>gi|222537734 hypothetical protein LOC349633 [Homo sapiens]
          Length = 207

 Score =  406 bits (1044), Expect = e-114
 Identities = 207/207 (100%), Positives = 207/207 (100%)

Query: 1   MAVFHDMLLQPLGMFLCLSLQLSSATFIRYSSTCFTFDEYYTITLDIKASSHIYESNAVY 60
           MAVFHDMLLQPLGMFLCLSLQLSSATFIRYSSTCFTFDEYYTITLDIKASSHIYESNAVY
Sbjct: 1   MAVFHDMLLQPLGMFLCLSLQLSSATFIRYSSTCFTFDEYYTITLDIKASSHIYESNAVY 60

Query: 61  SVFVPVNDSVYAVVMKTLDENSDSAGLWQRADKNCYSNSTYYVKDQYMTVLEAQWQAPEP 120
           SVFVPVNDSVYAVVMKTLDENSDSAGLWQRADKNCYSNSTYYVKDQYMTVLEAQWQAPEP
Sbjct: 61  SVFVPVNDSVYAVVMKTLDENSDSAGLWQRADKNCYSNSTYYVKDQYMTVLEAQWQAPEP 120

Query: 121 ENITEVEIQAFTVQIRALPILSTLKLREKLSTLALAAKIPQSSAFKPFFMITPKSIRLEG 180
           ENITEVEIQAFTVQIRALPILSTLKLREKLSTLALAAKIPQSSAFKPFFMITPKSIRLEG
Sbjct: 121 ENITEVEIQAFTVQIRALPILSTLKLREKLSTLALAAKIPQSSAFKPFFMITPKSIRLEG 180

Query: 181 LANQVFSSPITEAIYILLAFLTSTLLF 207
           LANQVFSSPITEAIYILLAFLTSTLLF
Sbjct: 181 LANQVFSSPITEAIYILLAFLTSTLLF 207


>gi|31742482 arylsulfatase F precursor [Homo sapiens]
          Length = 590

 Score = 30.8 bits (68), Expect = 0.85
 Identities = 31/138 (22%), Positives = 60/138 (43%), Gaps = 16/138 (11%)

Query: 18  LSLQLSSATFIRYSSTCFTFDEYYTITLDIKASSHIYESNAVYSVFVPVNDSVYAVVMKT 77
           L+  +S+A+    S + F    Y   +  + + +     N      +P+N++  A ++K 
Sbjct: 68  LTQHISAASLCSPSRSAFLTGRYPIRSGMVSSGNRRVIQNLAVPAGLPLNETTLAALLKK 127

Query: 78  LDENSDSAGLWQRADKNCYSNSTY------YVKDQY----MTVLEAQWQAPEPENITEVE 127
              ++   G W +   NC S S        Y  D Y     T++++ W  P+P   TE+ 
Sbjct: 128 QGYSTGLIGKWHQG-LNCDSRSDQCHHPYNYGFDYYYGMPFTLVDSCW--PDPSRNTELA 184

Query: 128 IQA---FTVQIRALPILS 142
            ++     VQ+ A+ IL+
Sbjct: 185 FESQLWLCVQLVAIAILT 202


>gi|84626580 hypothetical protein LOC80178 [Homo sapiens]
          Length = 433

 Score = 30.4 bits (67), Expect = 1.1
 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 3/72 (4%)

Query: 82  SDSAGLWQRADKNCYSNST--YYVKDQYMTVLEAQWQAPEPENITEVEIQAFTVQIRALP 139
           S ++ LW +      S+ST     K Q++  ++     P+P  ++ VE++A   ++R   
Sbjct: 216 SQNSSLWAQLSSTQTSDSTDAAAAKTQFLQNMQTASGGPQPR-LSAVEVEAEAGRLRKAC 274

Query: 140 ILSTLKLREKLS 151
            L  L++RE+LS
Sbjct: 275 SLLRLRMREELS 286


>gi|8051636 tRNA exportin [Homo sapiens]
          Length = 962

 Score = 29.6 bits (65), Expect = 1.9
 Identities = 21/91 (23%), Positives = 40/91 (43%)

Query: 39  EYYTITLDIKASSHIYESNAVYSVFVPVNDSVYAVVMKTLDENSDSAGLWQRADKNCYSN 98
           E+  +   I A   I  S  +  +F+P+  +++ V+++  +EN  SA L ++  +  Y  
Sbjct: 741 EFIPLINQITAKFKIQVSPFLQQMFMPLLHAIFEVLLRPAEENDQSAALEKQMLRRSYFA 800

Query: 99  STYYVKDQYMTVLEAQWQAPEPENITEVEIQ 129
               V    M+ + A   A   E +    IQ
Sbjct: 801 FLQTVTGSGMSEVIANQGAENVERVLVTVIQ 831


>gi|57634534 nucleoporin 205kDa [Homo sapiens]
          Length = 2012

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 2/94 (2%)

Query: 13   GMFLCLSLQLSSATFIRYSSTCFT--FDEYYTITLDIKASSHIYESNAVYSVFVPVNDSV 70
            G    L+  LS A       T      + +Y   LD   +S   E N +       + S+
Sbjct: 1337 GAVFTLTAHLSQAVLTEQKQTSVLGPAEAHYAFMLDSCFTSPPPEENPLVGFASIGDSSL 1396

Query: 71   YAVVMKTLDENSDSAGLWQRADKNCYSNSTYYVK 104
            Y ++ K LD    + G +QR   + Y +  YY++
Sbjct: 1397 YIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQ 1430


>gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens]
          Length = 3095

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 15/60 (25%), Positives = 29/60 (48%)

Query: 110 VLEAQWQAPEPENITEVEIQAFTVQIRALPILSTLKLREKLSTLALAAKIPQSSAFKPFF 169
           ++E     P+PE +TEV     + QI+    L T ++ +K+  L     + +  + + FF
Sbjct: 785 IMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFF 844


>gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens]
          Length = 3069

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 15/60 (25%), Positives = 29/60 (48%)

Query: 110 VLEAQWQAPEPENITEVEIQAFTVQIRALPILSTLKLREKLSTLALAAKIPQSSAFKPFF 169
           ++E     P+PE +TEV     + QI+    L T ++ +K+  L     + +  + + FF
Sbjct: 785 IMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFF 844


>gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens]
          Length = 3174

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 15/60 (25%), Positives = 29/60 (48%)

Query: 110 VLEAQWQAPEPENITEVEIQAFTVQIRALPILSTLKLREKLSTLALAAKIPQSSAFKPFF 169
           ++E     P+PE +TEV     + QI+    L T ++ +K+  L     + +  + + FF
Sbjct: 785 IMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFF 844


>gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens]
          Length = 3135

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 15/60 (25%), Positives = 29/60 (48%)

Query: 110 VLEAQWQAPEPENITEVEIQAFTVQIRALPILSTLKLREKLSTLALAAKIPQSSAFKPFF 169
           ++E     P+PE +TEV     + QI+    L T ++ +K+  L     + +  + + FF
Sbjct: 785 IMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFF 844


>gi|46409390 transmembrane protein 179 [Homo sapiens]
          Length = 197

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 7/85 (8%)

Query: 122 NITEVEIQAFTVQIRALPILSTLKLREKLSTLALAAKIPQSSAFKPFFMITPKSIRLEGL 181
           N+T  E + FTVQ    P      L   L +L LAA    + A++  F +       EG 
Sbjct: 51  NLTVQERERFTVQEWGPPAACRFSLLASLLSLLLAA----AHAWRTLFFLCKGH---EGS 103

Query: 182 ANQVFSSPITEAIYILLAFLTSTLL 206
               F + +  A  + L F+ ST++
Sbjct: 104 FFSAFLNLLVSAFVVFLVFIASTIV 128


>gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score = 28.1 bits (61), Expect = 5.5
 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 7/98 (7%)

Query: 56  SNAVYSVFVPVND----SVYAVVMKTLDENSDSAGLWQRADKNCYSN--STYYVKDQYMT 109
           S A YSV++P N+    S+++V+    D N +S  ++  A+     +  STY   +    
Sbjct: 453 SQASYSVYLPENNARGTSIFSVIAYDPDSNENSRVIYSLAEDTIQGSPLSTYVSINSDTG 512

Query: 110 VLEAQWQAPEPENITEVEIQAFTVQIRALPILSTLKLR 147
           VL A     + E   ++++Q       + P+ S + LR
Sbjct: 513 VLYALCSF-DYEQFRDLQMQVTASDSGSPPLSSNVSLR 549


>gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precursor
           [Homo sapiens]
          Length = 828

 Score = 28.1 bits (61), Expect = 5.5
 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 7/98 (7%)

Query: 56  SNAVYSVFVPVND----SVYAVVMKTLDENSDSAGLWQRADKNCYSN--STYYVKDQYMT 109
           S A YSV++P N+    S+++V+    D N +S  ++  A+     +  STY   +    
Sbjct: 453 SQASYSVYLPENNARGTSIFSVIAYDPDSNENSRVIYSLAEDTIQGSPLSTYVSINSDTG 512

Query: 110 VLEAQWQAPEPENITEVEIQAFTVQIRALPILSTLKLR 147
           VL A     + E   ++++Q       + P+ S + LR
Sbjct: 513 VLYALCSF-DYEQFRDLQMQVTASDSGSPPLSSNVSLR 549


>gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Homo
           sapiens]
          Length = 823

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 16/63 (25%), Positives = 29/63 (46%), Gaps = 3/63 (4%)

Query: 18  LSLQLSSATFIRYSSTCFTFDEYYTITLDIKASSHIYESNAVYSVFVPVNDSVYAVVMKT 77
           L++ L     +     C T D Y    L+ K    +Y+S  +Y    PV D +  + +++
Sbjct: 196 LTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKT---LYKSKVIYKNLNPVWDEIVVLPIQS 252

Query: 78  LDE 80
           LD+
Sbjct: 253 LDQ 255


>gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Homo
           sapiens]
          Length = 878

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 16/63 (25%), Positives = 29/63 (46%), Gaps = 3/63 (4%)

Query: 18  LSLQLSSATFIRYSSTCFTFDEYYTITLDIKASSHIYESNAVYSVFVPVNDSVYAVVMKT 77
           L++ L     +     C T D Y    L+ K    +Y+S  +Y    PV D +  + +++
Sbjct: 196 LTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKT---LYKSKVIYKNLNPVWDEIVVLPIQS 252

Query: 78  LDE 80
           LD+
Sbjct: 253 LDQ 255


>gi|14249428 leucine-rich repeats and calponin homology (CH) domain
           containing 3 [Homo sapiens]
          Length = 712

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 15/46 (32%), Positives = 24/46 (52%), Gaps = 8/46 (17%)

Query: 150 LSTLALAAKIPQSSAFKPFFMITPKSIRLEGLANQVFSSPITEAIY 195
           L+ +  AA +P SSAF P        ++ +   N + SSP TE ++
Sbjct: 553 LNQVGCAATLPHSSAFTP--------LKSDDRPNALLSSPATETVH 590


>gi|14670350 general transcription factor II, i isoform 1 [Homo
           sapiens]
          Length = 998

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 39/162 (24%), Positives = 63/162 (38%), Gaps = 14/162 (8%)

Query: 38  DEYYTITLDIKASSHIYESNAVYSVFVPVNDSVYAVVMKTLDENSDSAGLWQRADKNCYS 97
           DE   ++  ++ S H  E N    + VP  DS   V      E S+   +    + + YS
Sbjct: 264 DEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP----SETSEDPEVEVTIEDDDYS 319

Query: 98  NSTYYVKDQYMTVLEAQWQAPEPENITEVEIQAFTVQIRALPILSTLK----LREKLSTL 153
             +   K   +     Q   PEP N  + +++ F  +     I    K    L E+    
Sbjct: 320 PPSKRPKANEL----PQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQ 375

Query: 154 ALAAKIPQSSAFKPFFMITPKSIRLEGLANQV-FSSPITEAI 194
           A+ AK P +  + P F    + + +EGL   + F  P T  I
Sbjct: 376 AIKAKGPVTIPY-PLFQSHVEDLYVEGLPEGIPFRRPSTYGI 416


>gi|209571547 kelch repeat and BTB (POZ) domain containing 4 isoform
           a [Homo sapiens]
          Length = 534

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 12/39 (30%), Positives = 23/39 (58%)

Query: 62  VFVPVNDSVYAVVMKTLDENSDSAGLWQRADKNCYSNST 100
           V VP  D++Y++  KTL +   +A ++ R   N ++ +T
Sbjct: 340 VSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETT 378


>gi|209693446 kelch repeat and BTB (POZ) domain containing 4 isoform
           b [Homo sapiens]
          Length = 518

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 12/39 (30%), Positives = 23/39 (58%)

Query: 62  VFVPVNDSVYAVVMKTLDENSDSAGLWQRADKNCYSNST 100
           V VP  D++Y++  KTL +   +A ++ R   N ++ +T
Sbjct: 324 VSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETT 362


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.132    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,615,189
Number of Sequences: 37866
Number of extensions: 246887
Number of successful extensions: 627
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 618
Number of HSP's gapped (non-prelim): 18
length of query: 207
length of database: 18,247,518
effective HSP length: 98
effective length of query: 109
effective length of database: 14,536,650
effective search space: 1584494850
effective search space used: 1584494850
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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