BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|222446620 hypothetical protein LOC342346 [Homo sapiens] (1141 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|222446620 hypothetical protein LOC342346 [Homo sapiens] 2282 0.0 gi|14149793 glutamine rich 2 [Homo sapiens] 107 6e-23 gi|24307909 ral guanine nucleotide dissociation stimulator isofo... 62 2e-09 gi|108796058 ral guanine nucleotide dissociation stimulator isof... 62 2e-09 gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 62 3e-09 gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 62 3e-09 gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 62 3e-09 gi|11386183 WAS protein family, member 2 [Homo sapiens] 60 1e-08 gi|7706501 WW domain binding protein 11 [Homo sapiens] 58 4e-08 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 57 1e-07 gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho... 56 2e-07 gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 56 2e-07 gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 55 5e-07 gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 54 8e-07 gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 52 4e-06 gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 52 4e-06 gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 52 4e-06 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 50 9e-06 gi|163965366 nascent polypeptide-associated complex alpha subuni... 50 9e-06 gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 50 1e-05 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 50 1e-05 gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 50 1e-05 gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi... 50 1e-05 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 50 1e-05 gi|50428940 mediator complex subunit 25 [Homo sapiens] 50 2e-05 gi|146134388 YLP motif containing 1 [Homo sapiens] 50 2e-05 gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] 49 3e-05 gi|150170670 piccolo isoform 2 [Homo sapiens] 49 3e-05 gi|150378539 piccolo isoform 1 [Homo sapiens] 49 3e-05 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 49 3e-05 >gi|222446620 hypothetical protein LOC342346 [Homo sapiens] Length = 1141 Score = 2282 bits (5913), Expect = 0.0 Identities = 1141/1141 (100%), Positives = 1141/1141 (100%) Query: 1 MSFSLTFTELANIAIPQCGVLNFKALHLLLHGILEHIHMAELKKVLSGDEDFLQTSQVVI 60 MSFSLTFTELANIAIPQCGVLNFKALHLLLHGILEHIHMAELKKVLSGDEDFLQTSQVVI Sbjct: 1 MSFSLTFTELANIAIPQCGVLNFKALHLLLHGILEHIHMAELKKVLSGDEDFLQTSQVVI 60 Query: 61 MPREGDAQPILNPMKRLSNVFDHVVSRLDKLENQLALLQDLPSTAQLLEASQGTARPVQD 120 MPREGDAQPILNPMKRLSNVFDHVVSRLDKLENQLALLQDLPSTAQLLEASQGTARPVQD Sbjct: 61 MPREGDAQPILNPMKRLSNVFDHVVSRLDKLENQLALLQDLPSTAQLLEASQGTARPVQD 120 Query: 121 LWHLIKLRKMVEGHDEVMAKSMQTLQDLLTDLHALQVTITALRKEVDMLKNMLDKVHPER 180 LWHLIKLRKMVEGHDEVMAKSMQTLQDLLTDLHALQVTITALRKEVDMLKNMLDKVHPER Sbjct: 121 LWHLIKLRKMVEGHDEVMAKSMQTLQDLLTDLHALQVTITALRKEVDMLKNMLDKVHPER 180 Query: 181 MDIFAEDFKIQNWKMVALQREVASLQNKFKTIPKTEDMVLWSGLHDAMFTSEIGSSPLDL 240 MDIFAEDFKIQNWKMVALQREVASLQNKFKTIPKTEDMVLWSGLHDAMFTSEIGSSPLDL Sbjct: 181 MDIFAEDFKIQNWKMVALQREVASLQNKFKTIPKTEDMVLWSGLHDAMFTSEIGSSPLDL 240 Query: 241 WQSVEQLPEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSL 300 WQSVEQLPEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSL Sbjct: 241 WQSVEQLPEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSL 300 Query: 301 SRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTP 360 SRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTP Sbjct: 301 SRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTP 360 Query: 361 GSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQP 420 GSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQP Sbjct: 361 GSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQP 420 Query: 421 SRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLRERARKDGAPK 480 SRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLRERARKDGAPK Sbjct: 421 SRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLRERARKDGAPK 480 Query: 481 DRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGGKDGDPK 540 DRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGGKDGDPK Sbjct: 481 DRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGGKDGDPK 540 Query: 541 DRVGKDGAPKEAQPKAPQSALHRLKTTAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAP 600 DRVGKDGAPKEAQPKAPQSALHRLKTTAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAP Sbjct: 541 DRVGKDGAPKEAQPKAPQSALHRLKTTAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAP 600 Query: 601 ATKMAAIATDTAAAGPLGVFADVLGAGPSRGATESQILGDDSEIYEILSPSYSAASIGPD 660 ATKMAAIATDTAAAGPLGVFADVLGAGPSRGATESQILGDDSEIYEILSPSYSAASIGPD Sbjct: 601 ATKMAAIATDTAAAGPLGVFADVLGAGPSRGATESQILGDDSEIYEILSPSYSAASIGPD 660 Query: 661 PALSQAMVATKQAMSPEDKKRAVKYSMSHIAQIPVKHDSLKEEFAQLSCNLNQRLSYLAN 720 PALSQAMVATKQAMSPEDKKRAVKYSMSHIAQIPVKHDSLKEEFAQLSCNLNQRLSYLAN Sbjct: 661 PALSQAMVATKQAMSPEDKKRAVKYSMSHIAQIPVKHDSLKEEFAQLSCNLNQRLSYLAN 720 Query: 721 MGGPSSLGTTVDILQKKIGSLQKSRLKEEELERIWGNQIEMMKDRYITLDKAVENLQIRM 780 MGGPSSLGTTVDILQKKIGSLQKSRLKEEELERIWGNQIEMMKDRYITLDKAVENLQIRM Sbjct: 721 MGGPSSLGTTVDILQKKIGSLQKSRLKEEELERIWGNQIEMMKDRYITLDKAVENLQIRM 780 Query: 781 DEFKTLQAQIKRLEMNKVNKSTMEEELREKADRSALAGKASRVDLETVALELNEMIQGIL 840 DEFKTLQAQIKRLEMNKVNKSTMEEELREKADRSALAGKASRVDLETVALELNEMIQGIL Sbjct: 781 DEFKTLQAQIKRLEMNKVNKSTMEEELREKADRSALAGKASRVDLETVALELNEMIQGIL 840 Query: 841 FKVTIHEDSWKKAMEELSKDVNTKLVHSDLDPLKKEMEEVWKIVRKLLIEGLRLDPDSAA 900 FKVTIHEDSWKKAMEELSKDVNTKLVHSDLDPLKKEMEEVWKIVRKLLIEGLRLDPDSAA Sbjct: 841 FKVTIHEDSWKKAMEELSKDVNTKLVHSDLDPLKKEMEEVWKIVRKLLIEGLRLDPDSAA 900 Query: 901 GFRRKLFKRVKCISCDRPVEMMTGPQLITIRKAHLLSRLRPASANSCEYLQRQQMREQQW 960 GFRRKLFKRVKCISCDRPVEMMTGPQLITIRKAHLLSRLRPASANSCEYLQRQQMREQQW Sbjct: 901 GFRRKLFKRVKCISCDRPVEMMTGPQLITIRKAHLLSRLRPASANSCEYLQRQQMREQQW 960 Query: 961 LQLQDLGIQEDCQQDWGDGPQNATSLKCKSCNLLTLYPYGDPHVIDYDSAEVDILGVDGI 1020 LQLQDLGIQEDCQQDWGDGPQNATSLKCKSCNLLTLYPYGDPHVIDYDSAEVDILGVDGI Sbjct: 961 LQLQDLGIQEDCQQDWGDGPQNATSLKCKSCNLLTLYPYGDPHVIDYDSAEVDILGVDGI 1020 Query: 1021 LYKGRVNSQRGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSA 1080 LYKGRVNSQRGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSA Sbjct: 1021 LYKGRVNSQRGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSA 1080 Query: 1081 ASGPHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPAN 1140 ASGPHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPAN Sbjct: 1081 ASGPHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPAN 1140 Query: 1141 P 1141 P Sbjct: 1141 P 1141 >gi|14149793 glutamine rich 2 [Homo sapiens] Length = 1663 Score = 107 bits (267), Expect = 6e-23 Identities = 69/209 (33%), Positives = 111/209 (53%), Gaps = 13/209 (6%) Query: 725 SSLGTTVDILQKKIGSLQKSRLK---------EEELERIWGNQIEMMKD---RYITLDKA 772 S+L + LQ + SL SR EE L R+ +++ D IT Sbjct: 1225 STLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNL 1284 Query: 773 VENLQIRMDEFKTLQAQIKRLEMNKVNKSTMEEELREKADRSALAGKASRVDLETVALEL 832 +E+ + + + L +++LE K N+ +E E+ KAD+SALA K SRV + +L Sbjct: 1285 IEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQL 1344 Query: 833 NEMIQGILFKVTIHEDSWKKAMEELSKDVNTKLVHSDLDPLKKEMEEVWKIVRKLLIEGL 892 N M+Q ++ K++ E W+K ++ L +++ KL +LDP+K+ +E+ WK +R+ L E Sbjct: 1345 NHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRWKSLRQQLRERP 1404 Query: 893 RL-DPDSAAGFRRKLFKRVKCISCDRPVE 920 L D AA RR+L C+SCDRP+E Sbjct: 1405 PLYQADEAAAMRRQLLAHFHCLSCDRPLE 1433 Score = 30.8 bits (68), Expect = 7.7 Identities = 12/19 (63%), Positives = 18/19 (94%) Query: 1011 EVDILGVDGILYKGRVNSQ 1029 EVDILG+DG +YKGR++++ Sbjct: 1592 EVDILGLDGHIYKGRMDTR 1610 >gi|24307909 ral guanine nucleotide dissociation stimulator isoform 1 [Homo sapiens] Length = 914 Score = 62.4 bits (150), Expect = 2e-09 Identities = 46/129 (35%), Positives = 57/129 (44%), Gaps = 14/129 (10%) Query: 265 IQVSEPVQ-NPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAP----G 319 ++ SEP++ P+ L V P L P A++ +RA P PA PE AP G Sbjct: 248 LEHSEPIEAEPEALSPV-----PALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPG 302 Query: 320 CTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQ 379 E AP PAP + P +GLE P PAL P P P AP L PAP Sbjct: 303 SELEVAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDP----APSQTLELEPAPAPV 358 Query: 380 PPPLGDWPA 388 P WP+ Sbjct: 359 PSLQPSWPS 367 Score = 56.6 bits (135), Expect = 1e-07 Identities = 47/131 (35%), Positives = 52/131 (39%), Gaps = 8/131 (6%) Query: 276 LLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPV 335 LL + H E E PE S + P ALTP AP AP P P P Sbjct: 244 LLAQLEHSEPIEAEPEALSPVP---ALKPTPELELALTPARAPSPVPAPAPEPEPAPTPA 300 Query: 336 PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPL 395 PG EL + P P L P P+V G AP P L PAP P P P P+ Sbjct: 301 PGSELEVAPAPAPELQQAPEPAV--GLESAPAPALELEPAPEQDPAPSQTLELEPAPAPV 358 Query: 396 PQGWPRVGSWP 406 P P SWP Sbjct: 359 PSLQP---SWP 366 >gi|108796058 ral guanine nucleotide dissociation stimulator isoform 2 [Homo sapiens] Length = 859 Score = 62.4 bits (150), Expect = 2e-09 Identities = 46/129 (35%), Positives = 57/129 (44%), Gaps = 14/129 (10%) Query: 265 IQVSEPVQ-NPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAP----G 319 ++ SEP++ P+ L V P L P A++ +RA P PA PE AP G Sbjct: 193 LEHSEPIEAEPEALSPV-----PALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPG 247 Query: 320 CTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQ 379 E AP PAP + P +GLE P PAL P P P AP L PAP Sbjct: 248 SELEVAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDP----APSQTLELEPAPAPV 303 Query: 380 PPPLGDWPA 388 P WP+ Sbjct: 304 PSLQPSWPS 312 Score = 56.6 bits (135), Expect = 1e-07 Identities = 47/131 (35%), Positives = 52/131 (39%), Gaps = 8/131 (6%) Query: 276 LLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPV 335 LL + H E E PE S + P ALTP AP AP P P P Sbjct: 189 LLAQLEHSEPIEAEPEALSPVP---ALKPTPELELALTPARAPSPVPAPAPEPEPAPTPA 245 Query: 336 PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPL 395 PG EL + P P L P P+V G AP P L PAP P P P P+ Sbjct: 246 PGSELEVAPAPAPELQQAPEPAV--GLESAPAPALELEPAPEQDPAPSQTLELEPAPAPV 303 Query: 396 PQGWPRVGSWP 406 P P SWP Sbjct: 304 PSLQP---SWP 311 >gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 62.0 bits (149), Expect = 3e-09 Identities = 37/100 (37%), Positives = 42/100 (42%), Gaps = 3/100 (3%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQP---PALTPESAPGCTTEFAPGPAPGTEPVPGLELGL 342 P L P S + + Q P+ P PA TP P AP PAP PV Sbjct: 106 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVA 165 Query: 343 ELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382 L P PA P P P+ P + PAP P P PAP P P Sbjct: 166 VLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 205 Score = 54.7 bits (130), Expect = 5e-07 Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 14/96 (14%) Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLEL 344 VP P + L+ A PA P P +AP AP PAP P P Sbjct: 128 VPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA------- 180 Query: 345 EPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P P P P P+ PAP P P PAP A P Sbjct: 181 -PAPVAAPAPAPA------PAPAPAPAPAPAPDAAP 209 Score = 45.1 bits (105), Expect = 4e-04 Identities = 44/153 (28%), Positives = 52/153 (33%), Gaps = 35/153 (22%) Query: 288 LLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPV 347 LL A AV++S EPA E AP P PAP + P PV Sbjct: 92 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPS-VPVPAPASTP----------PPV 140 Query: 348 PALGPVPGPSVTPGSLPAPWPVL--------GPVPAPGAQPPPLGDWPALPRRWPLPQGW 399 P L P P P+ P + P PV P PAP P P+ P P P Sbjct: 141 PVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 200 Query: 400 PRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGS 432 P P P AP + E G+ Sbjct: 201 P----------------APAPDAAPQESAEQGA 217 Score = 35.8 bits (81), Expect = 0.24 Identities = 27/103 (26%), Positives = 33/103 (32%), Gaps = 8/103 (7%) Query: 260 EATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPG 319 E ++ V P P + + P P + A PA PA P AP Sbjct: 123 EQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPA 182 Query: 320 CTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGS 362 AP PAP P P P PA P S G+ Sbjct: 183 PVAAPAPAPAPAPAPAPA--------PAPAPDAAPQESAEQGA 217 >gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 62.0 bits (149), Expect = 3e-09 Identities = 37/100 (37%), Positives = 42/100 (42%), Gaps = 3/100 (3%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQP---PALTPESAPGCTTEFAPGPAPGTEPVPGLELGL 342 P L P S + + Q P+ P PA TP P AP PAP PV Sbjct: 106 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVA 165 Query: 343 ELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382 L P PA P P P+ P + PAP P P PAP P P Sbjct: 166 VLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 205 Score = 54.7 bits (130), Expect = 5e-07 Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 14/96 (14%) Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLEL 344 VP P + L+ A PA P P +AP AP PAP P P Sbjct: 128 VPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA------- 180 Query: 345 EPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P P P P P+ PAP P P PAP A P Sbjct: 181 -PAPVAAPAPAPA------PAPAPAPAPAPAPDAAP 209 Score = 45.1 bits (105), Expect = 4e-04 Identities = 44/153 (28%), Positives = 52/153 (33%), Gaps = 35/153 (22%) Query: 288 LLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPV 347 LL A AV++S EPA E AP P PAP + P PV Sbjct: 92 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPS-VPVPAPASTP----------PPV 140 Query: 348 PALGPVPGPSVTPGSLPAPWPVL--------GPVPAPGAQPPPLGDWPALPRRWPLPQGW 399 P L P P P+ P + P PV P PAP P P+ P P P Sbjct: 141 PVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 200 Query: 400 PRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGS 432 P P P AP + E G+ Sbjct: 201 P----------------APAPDAAPQESAEQGA 217 Score = 35.8 bits (81), Expect = 0.24 Identities = 27/103 (26%), Positives = 33/103 (32%), Gaps = 8/103 (7%) Query: 260 EATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPG 319 E ++ V P P + + P P + A PA PA P AP Sbjct: 123 EQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPA 182 Query: 320 CTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGS 362 AP PAP P P P PA P S G+ Sbjct: 183 PVAAPAPAPAPAPAPAPA--------PAPAPDAAPQESAEQGA 217 >gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo sapiens] Length = 316 Score = 62.0 bits (149), Expect = 3e-09 Identities = 37/100 (37%), Positives = 42/100 (42%), Gaps = 3/100 (3%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQP---PALTPESAPGCTTEFAPGPAPGTEPVPGLELGL 342 P L P S + + Q P+ P PA TP P AP PAP PV Sbjct: 117 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVA 176 Query: 343 ELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382 L P PA P P P+ P + PAP P P PAP P P Sbjct: 177 VLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216 Score = 54.7 bits (130), Expect = 5e-07 Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 14/96 (14%) Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLEL 344 VP P + L+ A PA P P +AP AP PAP P P Sbjct: 139 VPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA------- 191 Query: 345 EPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P P P P P+ PAP P P PAP A P Sbjct: 192 -PAPVAAPAPAPA------PAPAPAPAPAPAPDAAP 220 Score = 45.1 bits (105), Expect = 4e-04 Identities = 44/153 (28%), Positives = 52/153 (33%), Gaps = 35/153 (22%) Query: 288 LLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPV 347 LL A AV++S EPA E AP P PAP + P PV Sbjct: 103 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPS-VPVPAPASTP----------PPV 151 Query: 348 PALGPVPGPSVTPGSLPAPWPVL--------GPVPAPGAQPPPLGDWPALPRRWPLPQGW 399 P L P P P+ P + P PV P PAP P P+ P P P Sbjct: 152 PVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 211 Query: 400 PRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGS 432 P P P AP + E G+ Sbjct: 212 P----------------APAPDAAPQESAEQGA 228 Score = 35.8 bits (81), Expect = 0.24 Identities = 27/103 (26%), Positives = 33/103 (32%), Gaps = 8/103 (7%) Query: 260 EATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPG 319 E ++ V P P + + P P + A PA PA P AP Sbjct: 134 EQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPA 193 Query: 320 CTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGS 362 AP PAP P P P PA P S G+ Sbjct: 194 PVAAPAPAPAPAPAPAPA--------PAPAPDAAPQESAEQGA 228 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 60.1 bits (144), Expect = 1e-08 Identities = 46/136 (33%), Positives = 52/136 (38%), Gaps = 15/136 (11%) Query: 292 GSSAQAVSLSRAQEPAQPPALTP-ESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPAL 350 GS S P+ PP P S PG FAP PAP P P + + PV Sbjct: 283 GSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFG 342 Query: 351 GPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDL 410 P P +P S P P P P PPP D+P LP P P P G+ P Sbjct: 343 SPGTPPPPSPPSFPPHPDFAAPPPPP---PPPAADYPTLP---PPPLSQPTGGAPP---- 392 Query: 411 GVLRPTQPQPSRAPPP 426 P P P PPP Sbjct: 393 ----PPPPPPPPGPPP 404 Score = 43.9 bits (102), Expect = 9e-04 Identities = 49/171 (28%), Positives = 62/171 (36%), Gaps = 31/171 (18%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCT---TEFAPGPAPGTEPVP-----G 337 P L+ + S V A PP S+P + P PA + PV G Sbjct: 226 PTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSG 285 Query: 338 LELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQ 397 L V P P P + GS P P P P PAP PPP+ P P P Sbjct: 286 LAGPKRSSVVSPSHPPPAPPL--GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP----PV 339 Query: 398 GWPRVGSWPLWDLGVLRPTQPQ----------PSRAPPPATEFGSLWPRPL 438 G+ G+ P P+ P P PPPA ++ +L P PL Sbjct: 340 GFGSPGTPP-------PPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPL 383 Score = 36.2 bits (82), Expect = 0.18 Identities = 38/153 (24%), Positives = 55/153 (35%), Gaps = 16/153 (10%) Query: 1000 GDPHVIDYDSAEVDIL-GVDGILYKGRVNSQRGAQPLAVAKELAAVKAPSPPSQSLY--D 1056 G P + Y + + + VD Y S + P + + P PP++ Y D Sbjct: 223 GYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSP---SPSFSEDNLPPPPAEFSYPVD 279 Query: 1057 RVHSSALFG-----AICPPLCPRSSACSAASGPH---LTMPARPPSLPPLLLLPPLIP-- 1106 S L G + P P + + GP PA PP PP++ +PP P Sbjct: 280 NQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPV 339 Query: 1107 SLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPA 1139 P P + S PH + PP PA Sbjct: 340 GFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA 372 Score = 35.0 bits (79), Expect = 0.41 Identities = 30/85 (35%), Positives = 32/85 (37%), Gaps = 11/85 (12%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365 P PP +P S P AP P P P P + L P P P G P P Sbjct: 344 PGTPPPPSPPSFPPHPDFAAPPPPP---PPPAADYPT-LPPPPLSQPTGGAPPPPPPPPP 399 Query: 366 PWPVLGPVPAPGAQ-----PPPLGD 385 P P P P GA PPPL D Sbjct: 400 PGP--PPPPFTGADGQPAIPPPLSD 422 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 58.2 bits (139), Expect = 4e-08 Identities = 53/136 (38%), Positives = 57/136 (41%), Gaps = 22/136 (16%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPV---PGLELGLELEPVPALGPVPGPSVTPGS 362 P PP P PG T PGP PG P PG+ GL P+P L P PGP PG Sbjct: 412 PLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMP-GLR-GPLPRLLP-PGPP--PGR 466 Query: 363 LPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSR 422 P P P GP P PPP G P LP P P G P G++RP P Sbjct: 467 PPGPPP--GPPPGLPPGPPPRGPPPRLPP--PAPPGIPPPRP------GMMRPPLVPPLG 516 Query: 423 APPPATEFGSLWPRPL 438 PP G P PL Sbjct: 517 PAPP----GLFPPAPL 528 Score = 51.6 bits (122), Expect = 4e-06 Identities = 41/117 (35%), Positives = 42/117 (35%), Gaps = 18/117 (15%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFA----PGPAPGTEPVPGLELG 341 P L P G L P PP L P PG PGP PG P P Sbjct: 419 PPLRPPGPPT---GLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGP----- 470 Query: 342 LELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQG 398 P P L P P P P LP P P P P PG PPL +P P P G Sbjct: 471 -PPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPL-----VPPLGPAPPG 521 Score = 42.4 bits (98), Expect = 0.003 Identities = 45/145 (31%), Positives = 54/145 (37%), Gaps = 12/145 (8%) Query: 301 SRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTP 360 S A++ +Q + G +T + AP P + P LGP P P + P Sbjct: 364 SEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP 423 Query: 361 GSLPAPWPVLGPVPAPGAQP---PP-----LGDWPALPRRWPLPQGWPRVGSWPLWDLGV 412 P P L P P PGA P PP G P L P P P P L Sbjct: 424 ---PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPP 480 Query: 413 LRPTQPQPSRAPPPATEFGSLWPRP 437 P + P R PPPA G PRP Sbjct: 481 GPPPRGPPPRLPPPAPP-GIPPPRP 504 Score = 42.4 bits (98), Expect = 0.003 Identities = 35/102 (34%), Positives = 39/102 (38%), Gaps = 15/102 (14%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEP----------V 335 P L P G L R P PP P PG PGP P P + Sbjct: 440 PFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGI 499 Query: 336 PGLELGLELEP-VPALGPVPGPSVTPGSLPAPWPVLGPVPAP 376 P G+ P VP LGP P P + P PAP P G + AP Sbjct: 500 PPPRPGMMRPPLVPPLGPAP-PGLFP---PAPLPNPGVLSAP 537 Score = 39.3 bits (90), Expect = 0.022 Identities = 46/180 (25%), Positives = 71/180 (39%), Gaps = 22/180 (12%) Query: 352 PVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLG 411 P+P P ++ ++ +P PGAQPP + L + V PL G Sbjct: 140 PLPDMPHAPSNI-----LIQDIPLPGAQPPSI-----LKKTSAYGPPTRAVSILPLLGHG 189 Query: 412 VLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLRE 471 V R + PPP G P+ +Q Y + G AL L + + D+ L + Sbjct: 190 VPRLPPGRKPPGPPP----GPPPPQVVQMYGRKVGFALDLPP---RRRDEDMLYSPELAQ 242 Query: 472 RARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKD 531 R D + DG P+D D D D + DD D+ + D + H+D+ +D Sbjct: 243 RGHDDDV-SSTSEDDGYPED---MDQDKHDDS-TDDSDTDKSDGESDGDEFVHRDNGERD 297 Score = 33.1 bits (74), Expect = 1.5 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 1042 AAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLTMPARPPSLPPLLLL 1101 A+ + +PP ++ + + G PPL P + GP +P PP P L Sbjct: 386 ASSQQQAPPQSVPPSQIQAPPMPGP--PPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLR 443 Query: 1102 PPLIPSLRDP 1111 PP +P LR P Sbjct: 444 PPGMPGLRGP 453 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 56.6 bits (135), Expect = 1e-07 Identities = 86/340 (25%), Positives = 119/340 (35%), Gaps = 49/340 (14%) Query: 248 PEAALAQTTKYLEATRAIQVSEP----------VQNPQLLQTVWHYEVPELLPEGSSAQA 297 PE A+ K ++ ++VS VQ P+ T P P G+ A A Sbjct: 66 PERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATP---PAPPRAPRGAPAAA 122 Query: 298 VSLSRAQEPAQPP------ALTPESAPGCTTEFAPGP-APG-TEPVPGLELGLELEPVPA 349 + + PA PP A P AP A P +PG +P P + P Sbjct: 123 AAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQ-----RAAPL 177 Query: 350 LGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWD 409 P P P+ P P P P PA A+ PPL P P P Q P Sbjct: 178 AAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA--PPQQQQP--------- 226 Query: 410 LGVLRPTQPQPSRAPPPATEFGSLWP---RPLQPYQSRQGEA-LQLAAVQVKGEENDVPS 465 P QPQP G+ P R + Y G A +L +V+G + + Sbjct: 227 ----PPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAA 282 Query: 466 LRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHK 525 RG ER R R + G R ++ V + +D D +D + Sbjct: 283 ARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEED-DDEDEDEE 341 Query: 526 DDVPKDRGGKDGDPKDRVGKDGAPKEAQPKAPQSALHRLK 565 DDV + G + DR + + PQSA R+K Sbjct: 342 DDVSE---GSEVPESDRPAGAQHHQLNGERGPQSAKERVK 378 Score = 37.7 bits (86), Expect = 0.063 Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 26/122 (21%) Query: 1030 RGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLTMP 1089 RGA A A AP PP A A P PR++A +AA+ P P Sbjct: 116 RGAPAAAAAAAPPPTPAPPPPP----------APVAAAAPARAPRAAA-AAATAPPSPGP 164 Query: 1090 ARP----------PSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPA 1139 A+P + PP PP + P++AP +R P + PP+ PA Sbjct: 165 AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLP-----PPPQPPA 219 Query: 1140 NP 1141 P Sbjct: 220 PP 221 >gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo sapiens] Length = 245 Score = 56.2 bits (134), Expect = 2e-07 Identities = 58/189 (30%), Positives = 73/189 (38%), Gaps = 37/189 (19%) Query: 283 YEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAP--------GCTTEFAPGPAPGTEP 334 + + + LPE S A+ ++S + P QPP P S P + P P T P Sbjct: 5 FSLADALPEHSPAKTSAVSNTK-PGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVP 63 Query: 335 VPGLELGLELEPVPALGPVPGPSVT-PGSLPAPWPVLGPVPAP--------GAQPPPLGD 385 G+ VP GP PGP P S P+ P GP PAP G P P Sbjct: 64 FGPAPTGM-YPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMP 122 Query: 386 WPALPRRWPLPQG---------WPRVGSWPLW--DLGVLRPT------QPQPSRAPPPAT 428 +P LPR + P W + S P W +G PT P P APPP Sbjct: 123 FPELPRPYGAPTDPAAAGPLGPWGSMSSGP-WAPGMGGQYPTPNMPYPSPGPYPAPPPPQ 181 Query: 429 EFGSLWPRP 437 G+ P P Sbjct: 182 APGAAPPVP 190 Score = 52.8 bits (125), Expect = 2e-06 Identities = 68/245 (27%), Positives = 86/245 (35%), Gaps = 54/245 (22%) Query: 239 DLWQSVEQLPEAALAQT-----TKYLEATRAIQVSEPVQNPQLLQTVWH----YEVPELL 289 D + + LPE + A+T TK + + S P NP +V P + Sbjct: 3 DEFSLADALPEHSPAKTSAVSNTKPGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTV 62 Query: 290 PEGSSAQAV--SLSRAQEPAQPPALTPESAPGCTTEFAPGPAP--------GTEPVPGLE 339 P G + + S+ P PPA P S P C P PAP G P P + Sbjct: 63 PFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMP 122 Query: 340 L-------GLELEPVPA--LGPVPGPSVTP------GSLPAP---WPVLGPVPAPGAQPP 381 G +P A LGP S P G P P +P GP PAP PP Sbjct: 123 FPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAP---PP 179 Query: 382 PLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPY 441 P A P W G G+W P P AP + L+P P P+ Sbjct: 180 PQAPGAAPPVPW----GTVPPGAWG----------PPAPYPAPTGSYPTPGLYPTPSNPF 225 Query: 442 QSRQG 446 Q G Sbjct: 226 QVPSG 230 >gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] Length = 411 Score = 55.8 bits (133), Expect = 2e-07 Identities = 45/125 (36%), Positives = 55/125 (44%), Gaps = 6/125 (4%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEP--VPGLELGLELEP--VPALGPVPGPSVTPG 361 P PA P G + PGP PG P +PG G P VP GP+PGP P Sbjct: 156 PISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPI 215 Query: 362 SLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPS 421 S P P P+ GP+P P + P P G P P P P P P+ G + P P+ Sbjct: 216 SGPNPGPIPGPIPGPISGPNP-GPIPG-PISGPNPGLIPGPIPGPISGPGPIIGPIPSPA 273 Query: 422 RAPPP 426 + P P Sbjct: 274 QIPGP 278 Score = 55.8 bits (133), Expect = 2e-07 Identities = 50/145 (34%), Positives = 60/145 (41%), Gaps = 28/145 (19%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPA--LGPVPG--PSVTPG 361 P P P S P PGP PG P+PG G P+P GP PG P PG Sbjct: 206 PIPGPISGPISGPN------PGPIPG--PIPGPISGPNPGPIPGPISGPNPGLIPGPIPG 257 Query: 362 SLPAPWPVLGPVPAPGAQPPP---LGDWPAL-PRRWPLPQGWPRV------GSWPLWDLG 411 + P P++GP+P+P P P G P L P R P P + GS P G Sbjct: 258 PISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLPGLAPILGPGSGP--GSG 315 Query: 412 VLRPTQPQPSRAPPPATEFGSLWPR 436 + P P P PA LWP+ Sbjct: 316 SVPAPIPGPGSLPAPA----PLWPQ 336 Score = 53.9 bits (128), Expect = 8e-07 Identities = 43/129 (33%), Positives = 52/129 (40%), Gaps = 16/129 (12%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365 PAQ P P S PG A P+P P+PG G P P GP+PGP P +P Sbjct: 106 PAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPG 165 Query: 366 P------WPVLGPVPA--PGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQ 417 P P GP+P PG P P+ P P+P P S P+ + Sbjct: 166 PISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPI--------SG 217 Query: 418 PQPSRAPPP 426 P P P P Sbjct: 218 PNPGPIPGP 226 Score = 53.5 bits (127), Expect = 1e-06 Identities = 43/126 (34%), Positives = 53/126 (42%), Gaps = 8/126 (6%) Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLEL 344 +P +P A S P P P PG PGP G P+PG G Sbjct: 113 LPGSIPGPIPGPAQIPSPIPAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFS 172 Query: 345 EPVPALGPVPGPSVTPGSLPAP--WPVLGP--VPAPGAQPPPLGDWPALPRRWPLPQGWP 400 P P GP+PGP+ PG +P P P+ GP VP PG P P+ + P P+P P Sbjct: 173 GPNP--GPIPGPN--PGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIP 228 Query: 401 RVGSWP 406 S P Sbjct: 229 GPISGP 234 Score = 49.7 bits (117), Expect = 2e-05 Identities = 39/134 (29%), Positives = 52/134 (38%), Gaps = 15/134 (11%) Query: 294 SAQAVSLSRAQEPAQPPA-LTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGP 352 +A V + A P + P+ + P + P + PG G+ L P P P Sbjct: 43 AAPLVPAASASAPQRGPSGILPAAEPTICSLHQAWGGPGCRAQKGIPAALSPGPGPIPAP 102 Query: 353 VPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGV 412 +PGP+ PG LP P GP+P P P P+ P P P G P+ G Sbjct: 103 IPGPAQIPGPLPGSIP--GPIPGPAQIPSPI----------PAPIPGPISG--PVQIPGP 148 Query: 413 LRPTQPQPSRAPPP 426 R P P P P Sbjct: 149 FRGPIPGPISGPAP 162 Score = 48.5 bits (114), Expect = 4e-05 Identities = 39/120 (32%), Positives = 49/120 (40%), Gaps = 22/120 (18%) Query: 309 PPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPAL--GPVPGPSVTPGSLPA- 365 P AL+P P P P PG +PG P+P GP+PGP+ P +PA Sbjct: 89 PAALSPGPGP------IPAPIPGPAQIPG--------PLPGSIPGPIPGPAQIPSPIPAP 134 Query: 366 -PWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAP 424 P P+ GPV PG P+ + P P P P G P G + P P P Sbjct: 135 IPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNP----GPIPGPNPGPIPGP 190 Score = 48.5 bits (114), Expect = 4e-05 Identities = 33/107 (30%), Positives = 41/107 (38%), Gaps = 30/107 (28%) Query: 310 PALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSV----------- 358 P P G PGP PG PG +G P+P+ +PGP Sbjct: 236 PGPIPGPISGPNPGLIPGPIPGPISGPGPIIG----PIPSPAQIPGPGRLQGPGPILSPG 291 Query: 359 ---TPGSLPAPWPVLGP------------VPAPGAQPPPLGDWPALP 390 +PGSLP P+LGP +P PG+ P P WP P Sbjct: 292 RMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPLWPQSP 338 Score = 30.8 bits (68), Expect = 7.7 Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 26/72 (36%) Query: 298 VSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPS 357 +S R + P P L P PG GP G+ P P+PG Sbjct: 288 LSPGRMRSPGSLPGLAPILGPG------SGPGSGSVP----------------APIPG-- 323 Query: 358 VTPGSLPAPWPV 369 PGSLPAP P+ Sbjct: 324 --PGSLPAPAPL 333 >gi|62000702 diacylglycerol kinase kappa [Homo sapiens] Length = 1271 Score = 54.7 bits (130), Expect = 5e-07 Identities = 54/184 (29%), Positives = 65/184 (35%), Gaps = 19/184 (10%) Query: 306 PAQPPA------LTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVT 359 PA PPA +PE P E APGP P EL E P PA P P+ Sbjct: 37 PAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPE 96 Query: 360 PGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQ 419 P + PAP P P P P P P + P P + P P +L + Sbjct: 97 PATEPAPEPATEPAPEPA--PEPATESAPEPTPEPALESVPE----PAPELTPEVAPELA 150 Query: 420 PSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLRERARKDGAP 479 P P P TE + P + R A L V E RGL+ +P Sbjct: 151 PEPTPEPVTELAPEFCPEAAP-EFRPSPAPCLLQCPVDTRE------RGLKTSPSPSPSP 203 Query: 480 KDRT 483 RT Sbjct: 204 SPRT 207 Score = 50.1 bits (118), Expect = 1e-05 Identities = 63/187 (33%), Positives = 70/187 (37%), Gaps = 32/187 (17%) Query: 270 PVQNPQLLQTVWHYEVPELLPE---GSSAQAVSLSR-----------AQEPAQPPALTP- 314 P P LL +PE PE G +A S S A EPA PA P Sbjct: 39 PPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPA 98 Query: 315 -ESAPGCTTEFAPGPAP--GTEPVPGLELGLELEPVPALG--PVPGPSVTPGSLPAPWPV 369 E AP TE AP PAP TE P E P PAL P P P +TP P P Sbjct: 99 TEPAPEPATEPAPEPAPEPATESAP------EPTPEPALESVPEPAPELTPEVAPELAP- 151 Query: 370 LGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATE 429 P P P + P A P P P P + P+ T P PS +P P T Sbjct: 152 -EPTPEPVTELAPEFCPEAAPEFRPSPA--PCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208 Query: 430 FGSLWPR 436 W R Sbjct: 209 MS--WSR 213 Score = 47.8 bits (112), Expect = 6e-05 Identities = 41/139 (29%), Positives = 47/139 (33%), Gaps = 4/139 (2%) Query: 248 PEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPA 307 PEA T+ +EP P P P A + A EP Sbjct: 67 PEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPT 126 Query: 308 QPPAL--TPESAPGCTTEFAPGPAPGTEPVPGLELGLEL--EPVPALGPVPGPSVTPGSL 363 PAL PE AP T E AP AP P P EL E E P P P P + + Sbjct: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPV 186 Query: 364 PAPWPVLGPVPAPGAQPPP 382 L P+P P P Sbjct: 187 DTRERGLKTSPSPSPSPSP 205 Score = 38.9 bits (89), Expect = 0.028 Identities = 42/138 (30%), Positives = 52/138 (37%), Gaps = 25/138 (18%) Query: 348 PALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWP- 406 P G P S P P PWP P PAP PP L + A P P+P+ P + P Sbjct: 14 PQDGEQPAESPEP---PPPWPPPPPPPAPPPAPPLLSE--ASPE--PIPEPCPELAPGPC 66 Query: 407 ----------LWDLGVLRP-TQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQ 455 L+ P T+P AP PATE P P +P E A + Sbjct: 67 PEATSESATELYTEPTPEPATEPASEPAPEPATE-----PAP-EPATEPAPEPAPEPATE 120 Query: 456 VKGEENDVPSLRGLRERA 473 E P+L + E A Sbjct: 121 SAPEPTPEPALESVPEPA 138 Score = 33.9 bits (76), Expect = 0.91 Identities = 31/113 (27%), Positives = 36/113 (31%), Gaps = 12/113 (10%) Query: 329 APGTEPVPGLELGLELEPVPALGPVPGPSVT------------PGSLPAPWPVLGPVPAP 376 A GT P E E P P P P P +P P P L P P P Sbjct: 8 AQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCP 67 Query: 377 GAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATE 429 A + P P + P + T+P P AP PATE Sbjct: 68 EATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATE 120 >gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] Length = 1711 Score = 53.9 bits (128), Expect = 8e-07 Identities = 51/178 (28%), Positives = 63/178 (35%), Gaps = 24/178 (13%) Query: 265 IQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEF 324 + V PV + L+ +V +P S A + A P P L +S P + Sbjct: 225 LSVPAPVPHSGLVPV----QVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSAS 280 Query: 325 APGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLP------------APWPVLGP 372 P P + P G PVP P P P P S P AP VL P Sbjct: 281 VLVPVPASAPPSG--------PVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAP 332 Query: 373 VPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEF 430 VP P P P PA P +P P S P ++ P P AP PA F Sbjct: 333 VPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIF 390 Score = 46.2 bits (108), Expect = 2e-04 Identities = 45/151 (29%), Positives = 56/151 (37%), Gaps = 13/151 (8%) Query: 235 SSPLDLWQSV-EQLPEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGS 293 S+PL + SV +P +A L A +S PV P L P Sbjct: 272 SNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQ--------APVPP 323 Query: 294 SAQAVSLSRAQEP--AQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALG 351 SA + L+ P A PA TP +AP + P P P + P L P P Sbjct: 324 SAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPA 383 Query: 352 PVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382 P P P TP P P P P P + P P Sbjct: 384 PTPAPIFTPA--PTPMPAATPAAIPTSAPIP 412 Score = 42.7 bits (99), Expect = 0.002 Identities = 31/76 (40%), Positives = 36/76 (47%), Gaps = 14/76 (18%) Query: 318 PGCTTEFAPGPAPGTEPVPG-----------LELGLEL-EPVPALGPVPGPSVTPGSLPA 365 P TT F+P PAP P PG ++ L + PVP G VP T S+PA Sbjct: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVAT--SVPA 247 Query: 366 PWPVLGPVPAPGAQPP 381 P P L PVPA PP Sbjct: 248 PSPPLAPVPALAPAPP 263 Score = 41.6 bits (96), Expect = 0.004 Identities = 52/168 (30%), Positives = 60/168 (35%), Gaps = 40/168 (23%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELE 345 P P A L+ Q P P A T AP T AP PA T P Sbjct: 300 PAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPA-STPPA---------- 348 Query: 346 PVPALGPVPGPSVTPGSLP----------APWPVLGPVPA----PGAQPPPLGDWPALPR 391 PA VP P+ TP S P AP PV P PA P P P A+P Sbjct: 349 -APAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPT 407 Query: 392 RWPLPQGW------------PRVGSWPL-WDLG-VLRPTQPQPSRAPP 425 P+P + P + PL + G VL P+QP PP Sbjct: 408 SAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455 Score = 33.5 bits (75), Expect = 1.2 Identities = 40/125 (32%), Positives = 46/125 (36%), Gaps = 30/125 (24%) Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLP----APWPVLGPVPAPGAQP--- 380 P GT P+ + P P P PG + P S+P P V PVP G P Sbjct: 184 PVEGTLPL--VTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQV 241 Query: 381 --------PPLGDWPALPRRWPLPQGWPRV--GSWPL-WDLGVL-------RPTQPQPSR 422 PPL PAL P P P + S PL VL P+ P P Sbjct: 242 ATSVPAPSPPLAPVPALA---PAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLS 298 Query: 423 APPPA 427 AP PA Sbjct: 299 APAPA 303 >gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo sapiens] Length = 1125 Score = 51.6 bits (122), Expect = 4e-06 Identities = 82/339 (24%), Positives = 122/339 (35%), Gaps = 60/339 (17%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAP----GCTTEFAPGPAPGTEPVPGLELG 341 P LP Q VSL Q A P + ++ G P P P P L+ Sbjct: 792 PTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRF 851 Query: 342 LELEPVPA------LGPVPGPS----VTPGSLPAPWPVLGPVPAPGAQP----------- 380 + P P GP PGP P + P+P GP PG P Sbjct: 852 PLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGG 911 Query: 381 PPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQP 440 P D P + P Q P+ P + QP PS+ PPP + QP Sbjct: 912 PEDRDGRQQPPQQPQQQPQPQAPQQPQQQ----QQQQPPPSQQPPPTQQ---------QP 958 Query: 441 YQSRQGEALQLAAVQVK---GEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDV 497 Q R Q + + + G + + RER +D + +D + G+ Sbjct: 959 QQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRD---RREWGRRS 1015 Query: 498 DPKDRAHKDDVPKDRGG-----KDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEA 552 +DR H+D ++R ++ D +DR + + + RG + + DR G + K Sbjct: 1016 PDRDR-HRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGN---KTV 1071 Query: 553 QPKAPQ-------SALHRLKTTAAIAAAAAAAYAAATSS 584 +P Q S L + + AA+ + A ATSS Sbjct: 1072 EPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSS 1110 Score = 45.4 bits (106), Expect = 3e-04 Identities = 67/248 (27%), Positives = 86/248 (34%), Gaps = 52/248 (20%) Query: 241 WQSVEQLPEAALAQT----TKYLEATRAIQVSEPVQNPQL-LQTVWHYEVPELLPEGSSA 295 W+ + + PE +AQ T + E I PV P + + P++ P Sbjct: 630 WKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGP 689 Query: 296 QAVSLSRAQEPAQPPALTPESA---PGCTTEFAPGPAPGTEPVPGLELGLELEPVPA--L 350 V QPPA TP PG F PG P P P L G +P L Sbjct: 690 PVVGA------LQPPAFTPPLGIPPPG----FGPGVPPPPPPPPFLRPGFNPMHLPPGFL 739 Query: 351 GPVPGPSVTPG-SLPAPW--PVLGPVPAPGAQP-PPLGDW---------PALPRRWPLPQ 397 P P P +TP S+P P P+ P GA+ GD PA P P P Sbjct: 740 PPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPP 799 Query: 398 --------GWPRVGSWPLWDLGV-----------LRPTQPQPSRAPPPATEFGSLWPRPL 438 G V P+ L L P Q P PP F + PRP+ Sbjct: 800 VTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPM 859 Query: 439 QPYQSRQG 446 P+ +G Sbjct: 860 PPHMMHRG 867 Score = 31.6 bits (70), Expect = 4.5 Identities = 27/115 (23%), Positives = 40/115 (34%), Gaps = 17/115 (14%) Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLE----- 339 V E E ++A + A P P A P +A P AP P G++ Sbjct: 274 VEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYT 333 Query: 340 ------------LGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382 +G++ +P+ P+P PG P P P+ P P P Sbjct: 334 QHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP 388 >gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo sapiens] Length = 1132 Score = 51.6 bits (122), Expect = 4e-06 Identities = 82/339 (24%), Positives = 122/339 (35%), Gaps = 60/339 (17%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAP----GCTTEFAPGPAPGTEPVPGLELG 341 P LP Q VSL Q A P + ++ G P P P P L+ Sbjct: 799 PTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRF 858 Query: 342 LELEPVPA------LGPVPGPS----VTPGSLPAPWPVLGPVPAPGAQP----------- 380 + P P GP PGP P + P+P GP PG P Sbjct: 859 PLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGG 918 Query: 381 PPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQP 440 P D P + P Q P+ P + QP PS+ PPP + QP Sbjct: 919 PEDRDGRQQPPQQPQQQPQPQAPQQPQQQ----QQQQPPPSQQPPPTQQ---------QP 965 Query: 441 YQSRQGEALQLAAVQVK---GEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDV 497 Q R Q + + + G + + RER +D + +D + G+ Sbjct: 966 QQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRD---RREWGRRS 1022 Query: 498 DPKDRAHKDDVPKDRGG-----KDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEA 552 +DR H+D ++R ++ D +DR + + + RG + + DR G + K Sbjct: 1023 PDRDR-HRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGN---KTV 1078 Query: 553 QPKAPQ-------SALHRLKTTAAIAAAAAAAYAAATSS 584 +P Q S L + + AA+ + A ATSS Sbjct: 1079 EPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSS 1117 Score = 37.7 bits (86), Expect = 0.063 Identities = 66/271 (24%), Positives = 85/271 (31%), Gaps = 76/271 (28%) Query: 241 WQSVEQLPEAALAQT----TKYLEATRAIQVSEPVQNPQL-LQTVWHYEVPELLPEGSSA 295 W+ + + PE +AQ T + E I PV P + + P++ P Sbjct: 615 WKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGP 674 Query: 296 QAVSLSRAQEPAQPPALTPESA---PGCTTEFAPGPAPGTEPVPGLELGLELEPVPA--L 350 V QPPA TP PG F PG P P P L G +P L Sbjct: 675 PVVGA------LQPPAFTPPLGIPPPG----FGPGVPPPPPPPPFLRPGFNPMHLPPGFL 724 Query: 351 GPVPGPSVTPGSLPAPWPVLGPVPAPGA----------------QPPPL----------- 383 P P P +TP + P P P+ P + P P Sbjct: 725 PPGPPPPITP-PVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAES 783 Query: 384 GDW---------PALPRRWPLPQ--------GWPRVGSWPLWDLGV-----------LRP 415 GD PA P P P G V P+ L L P Sbjct: 784 GDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIP 843 Query: 416 TQPQPSRAPPPATEFGSLWPRPLQPYQSRQG 446 Q P PP F + PRP+ P+ +G Sbjct: 844 LQRPPGMPPPHLQRFPLMPPRPMPPHMMHRG 874 Score = 31.6 bits (70), Expect = 4.5 Identities = 27/115 (23%), Positives = 40/115 (34%), Gaps = 17/115 (14%) Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLE----- 339 V E E ++A + A P P A P +A P AP P G++ Sbjct: 259 VEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYT 318 Query: 340 ------------LGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382 +G++ +P+ P+P PG P P P+ P P P Sbjct: 319 QHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP 373 >gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo sapiens] Length = 1147 Score = 51.6 bits (122), Expect = 4e-06 Identities = 82/339 (24%), Positives = 122/339 (35%), Gaps = 60/339 (17%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAP----GCTTEFAPGPAPGTEPVPGLELG 341 P LP Q VSL Q A P + ++ G P P P P L+ Sbjct: 814 PTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRF 873 Query: 342 LELEPVPA------LGPVPGPS----VTPGSLPAPWPVLGPVPAPGAQP----------- 380 + P P GP PGP P + P+P GP PG P Sbjct: 874 PLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGG 933 Query: 381 PPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQP 440 P D P + P Q P+ P + QP PS+ PPP + QP Sbjct: 934 PEDRDGRQQPPQQPQQQPQPQAPQQPQQQ----QQQQPPPSQQPPPTQQ---------QP 980 Query: 441 YQSRQGEALQLAAVQVK---GEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDV 497 Q R Q + + + G + + RER +D + +D + G+ Sbjct: 981 QQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRD---RREWGRRS 1037 Query: 498 DPKDRAHKDDVPKDRGG-----KDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEA 552 +DR H+D ++R ++ D +DR + + + RG + + DR G + K Sbjct: 1038 PDRDR-HRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGN---KTV 1093 Query: 553 QPKAPQ-------SALHRLKTTAAIAAAAAAAYAAATSS 584 +P Q S L + + AA+ + A ATSS Sbjct: 1094 EPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSS 1132 Score = 37.7 bits (86), Expect = 0.063 Identities = 66/271 (24%), Positives = 85/271 (31%), Gaps = 76/271 (28%) Query: 241 WQSVEQLPEAALAQT----TKYLEATRAIQVSEPVQNPQL-LQTVWHYEVPELLPEGSSA 295 W+ + + PE +AQ T + E I PV P + + P++ P Sbjct: 630 WKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGP 689 Query: 296 QAVSLSRAQEPAQPPALTPESA---PGCTTEFAPGPAPGTEPVPGLELGLELEPVPA--L 350 V QPPA TP PG F PG P P P L G +P L Sbjct: 690 PVVGA------LQPPAFTPPLGIPPPG----FGPGVPPPPPPPPFLRPGFNPMHLPPGFL 739 Query: 351 GPVPGPSVTPGSLPAPWPVLGPVPAPGA----------------QPPPL----------- 383 P P P +TP + P P P+ P + P P Sbjct: 740 PPGPPPPITP-PVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAES 798 Query: 384 GDW---------PALPRRWPLPQ--------GWPRVGSWPLWDLGV-----------LRP 415 GD PA P P P G V P+ L L P Sbjct: 799 GDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIP 858 Query: 416 TQPQPSRAPPPATEFGSLWPRPLQPYQSRQG 446 Q P PP F + PRP+ P+ +G Sbjct: 859 LQRPPGMPPPHLQRFPLMPPRPMPPHMMHRG 889 Score = 31.6 bits (70), Expect = 4.5 Identities = 27/115 (23%), Positives = 40/115 (34%), Gaps = 17/115 (14%) Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLE----- 339 V E E ++A + A P P A P +A P AP P G++ Sbjct: 274 VEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYT 333 Query: 340 ------------LGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382 +G++ +P+ P+P PG P P P+ P P P Sbjct: 334 QHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP 388 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 50.4 bits (119), Expect = 9e-06 Identities = 53/160 (33%), Positives = 63/160 (39%), Gaps = 20/160 (12%) Query: 286 PELLPEGSSAQAVSLSRAQEPA--QPPALTPESAPGCTTEFAP---GPAPGTEPVPGLEL 340 P+ P+ +QA Q+P Q P L P APG +P P PG P L Sbjct: 955 PQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPL 1014 Query: 341 GLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWP 400 +L P PA P+P S G+LP P P GP P PPL PA R PQ P Sbjct: 1015 HTQLYPGPAQDPLPAHS---GALPFPSP--GP---PQPPHPPLAYGPAPSTRPMGPQAAP 1066 Query: 401 RVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQP 440 P + P P P PA G P P+ P Sbjct: 1067 LTIRGP----SSAGQSTPSPHLVPSPAPSPG---PGPVPP 1099 Score = 47.4 bits (111), Expect = 8e-05 Identities = 44/158 (27%), Positives = 57/158 (36%), Gaps = 20/158 (12%) Query: 290 PEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPA 349 P ++ ++ A P TP P C P P P P P P A Sbjct: 879 PATTTVDSIQAPIPSHTAPRPNPTPAPPPPCF----PVPPPQPLPTP------YTYPAGA 928 Query: 350 LGPVPGPSVTPGSLPA--PWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPL 407 P+P +PA P P +GP P P QP P + P + PLP P + +P Sbjct: 929 KQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHL--FPP 986 Query: 408 WDLGVLRPTQPQPSR------APPPATEFGSLWPRPLQ 439 G+L P P P PP L+P P Q Sbjct: 987 QAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQ 1024 Score = 42.7 bits (99), Expect = 0.002 Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 14/139 (10%) Query: 306 PAQPPALTPESAPGCTT--EFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSL 363 PA P A P + P + E A P T V ++ + P P P P Sbjct: 853 PAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPP------ 906 Query: 364 PAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRA 423 P +PV P P P P G +P + G P +P +G QPQP Sbjct: 907 PPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIP--AGFPAPRIG----PQPQPHPQ 960 Query: 424 PPPATEFGSLWPRPLQPYQ 442 P P+ FG P+ P Q Sbjct: 961 PHPSQAFGPQPPQQPLPLQ 979 Score = 42.4 bits (98), Expect = 0.003 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 28/102 (27%) Query: 289 LPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVP 348 LP S A +P PP A GPAP T P +G + P+ Sbjct: 1027 LPAHSGALPFPSPGPPQPPHPP-------------LAYGPAPSTRP-----MGPQAAPLT 1068 Query: 349 ALGP------VPGPSVTPGSLPAPWPVLGPVPA--PGAQPPP 382 GP P P + P P+P P GPVP P A+PPP Sbjct: 1069 IRGPSSAGQSTPSPHLVPSPAPSPGP--GPVPPRPPAAEPPP 1108 Score = 34.7 bits (78), Expect = 0.53 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGP 356 PA+PP L P S P T + P P + P+P E PVP P GP Sbjct: 1523 PAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPE-APSSGP 1572 Score = 33.1 bits (74), Expect = 1.5 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 25/89 (28%) Query: 341 GLELEPVPAL-GPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGW 399 GLE PV +L GP P + P SLP P+ P + PPPL PLP+ Sbjct: 1512 GLE-SPVASLPGPAEPPGLPPASLPESTPI------PSSSPPPLSS--------PLPEA- 1555 Query: 400 PRVGSWPLWDLGVLRPTQPQPSRAPPPAT 428 P+ P P PS PP ++ Sbjct: 1556 PQPKEEP--------PVPEAPSSGPPSSS 1576 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 50.4 bits (119), Expect = 9e-06 Identities = 89/334 (26%), Positives = 110/334 (32%), Gaps = 44/334 (13%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTT---EFAPGPAPGTEPVPGLELGL 342 P P + S P P A P G T + AP P T P P G Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP---KGG 999 Query: 343 ELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPA---LPRRWPLPQGW 399 P P P P P+VTP S P P P P GA PP P+ P PLP+G Sbjct: 1000 PATPSPKGAPTP-PAVTPPS-PKGSPAATPFP-KGASTPPAATPPSPKGSPAATPLPKGA 1056 Query: 400 PR--VGSWPLWDLGVLRPT---QPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAV 454 P + P G P+ P P A PP+ + G P P +G + AA Sbjct: 1057 PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP-------KGAPMPPAAT 1109 Query: 455 QVKGEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDV---PKD 511 PS +G GAP T P +GG P A P Sbjct: 1110 P--------PSPKGGLATPPHKGAP--TTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159 Query: 512 RGGKDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEAQPKAPQSALHRLKTTAAIA 571 +GG P A P PK + +PK A P P + K A Sbjct: 1160 KGGLATPPPKGA-----PTTPAATPPSPKGGLATP-SPKGA-PTTPAATPPSPKGGLATP 1212 Query: 572 AAAAAAYAAATSSAAQAAKVAAKFVKDAPATKMA 605 + A A + + +A K AP T A Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246 Score = 45.1 bits (105), Expect = 4e-04 Identities = 91/342 (26%), Positives = 113/342 (33%), Gaps = 54/342 (15%) Query: 309 PPALTPESAPGCTT----EFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTP---- 360 PPA TP S G + AP PA T P P G P P P P+ TP Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPK---GGPATSPPKGAPTP-PAATPPSPK 1321 Query: 361 GSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRP----- 415 GS P P P P P PP P LP P +G P + P G P Sbjct: 1322 GSPGTPPPKGAPTP-PAVTPPSPKGTPTLPATTPSSKGGP---TTPSSKEGPTPPAATPS 1377 Query: 416 -------TQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQL----AAVQVKGEENDVP 464 T P P R P + G + P ++ A + AA KG+ Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437 Query: 465 SLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAH 524 ++A APK P +G DP A PK+ PK A Sbjct: 1438 VTPVSLKKAPATSAPKG---GPATPSSKG----DPTLPAVTPPSPKEPPA----PKQVAT 1486 Query: 525 KDDVPKDRG--GKDGDPKDRVGKDGAPKEA--------QPKAPQSALHRLKTTAAIAAAA 574 K G P +PKE P AP + L KT A +A Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546 Query: 575 AAAYAAATSSAAQAAKVAAKFVKDAPATKMAAIATDTAAAGP 616 A A T + + A K+APAT + A+ A P Sbjct: 1547 ALIPPAMTVPSPKKTP-AIPTPKEAPATPSSKEASSPPAVTP 1587 Score = 40.4 bits (93), Expect = 0.010 Identities = 76/343 (22%), Positives = 100/343 (29%), Gaps = 49/343 (14%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELE 345 P P + S P P A P G T G P G Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257 Query: 346 PVPALGPVPGPSVTP----GSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPR 401 P P P P P+ TP G L P P PA P P G P P+G P Sbjct: 1258 PPPKGAPTP-PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP-----PKGAPT 1311 Query: 402 VGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEEN 461 + T P P +P G+ P + P + L KG Sbjct: 1312 PPA----------ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG--- 1358 Query: 462 DVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKD 521 G + K+G T P +GG + P +P +G DP Sbjct: 1359 ------GPTTPSSKEGP----TPPAATPSHKGGPAMTPPSPKRGPAIPSPKG----DPTS 1404 Query: 522 RAHKDDVPKDRGGKDGDPKDRVGKDGA--PKEAQPKAPQSALHRLKTTAAIAAAAAAAYA 579 A PK P V ++GA P + P LK A +A Sbjct: 1405 PAVIPLSPKKA------PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458 Query: 580 AATSSAAQAAKVAAKFVKDAPATKMAAIATD----TAAAGPLG 618 ++ V K+ PA K A ++ A P+G Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501 Score = 38.5 bits (88), Expect = 0.037 Identities = 80/312 (25%), Positives = 96/312 (30%), Gaps = 48/312 (15%) Query: 290 PEGSSA-----QAVSLSRAQEPAQP---PALTPESAPGCTTEFAPGPAPGTEPVPGLELG 341 P+GS A + S A P P PA TP TT A P+P P G Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078 Query: 342 LELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAP--GAQPPPLGDWPALPR-------- 391 P G TP AP P P+P G PP P P Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138 Query: 392 --RWPLPQGWPRV-GSWPLWDLGVLRPTQPQPSRAP------PPATEFGSLWP----RPL 438 P P+G P + P G L P P AP PP+ + G P P Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGL--ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196 Query: 439 QPYQSRQGEALQLAAVQVKGEEN----DVPSLRGLRERARKDGAPKDRTRKDGVPKDRGG 494 P + LA KG PS +G GAP T P +GG Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP--TTPAATPPSPKGG 1254 Query: 495 KDVDPKDRAHKDDV---PKDRGGKDVDPKDRAHKDDV---PKDRGGKDGDPKDRVGKDGA 548 P A P +GG P A V P +GG P Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA---PT 1311 Query: 549 PKEAQPKAPQSA 560 P A P +P+ + Sbjct: 1312 PPAATPPSPKGS 1323 Score = 37.4 bits (85), Expect = 0.082 Identities = 85/355 (23%), Positives = 110/355 (30%), Gaps = 49/355 (13%) Query: 291 EGSSAQAVSLSRAQEPAQPPALTPESAPGCT-TEFAPGPAPGTEPVPGLELGLELEPVPA 349 E + V+L +E PA P+ AP + T +P A T P P G+ P P Sbjct: 884 ETPTPSVVNLPFPKEGPATPA--PKQAPALSMTSSSPKKARAT-PAPK---GIPASPSPK 937 Query: 350 LGPVP---------GPSVTPGSLPAPWPVL--------GP-VPAPGAQPPPLGDWPALPR 391 P P G TP AP P GP P+P P P P P+ Sbjct: 938 GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997 Query: 392 ---RWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEA 448 P P+G P + + P P+ S A P + S P P A Sbjct: 998 GGPATPSPKGAPTPPA--------VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049 Query: 449 LQLAAVQVKGEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDV 508 L +PS +G GAP PK G PK Sbjct: 1050 TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG-GPATPSPKGAPMPPAA 1108 Query: 509 --PKDRGGKDVDPKDRAHKDDV---PKDRGGKDGDPKDRVGKDGAP--KEAQPKAPQSAL 561 P +GG P A P +GG P GAP A P +P+ L Sbjct: 1109 TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP-----PKGAPTTPAATPPSPKGGL 1163 Query: 562 HRLKTTAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAPATKMAAIATDTAAAGP 616 A AA + A + K A P + +AT + P Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1218 Score = 34.7 bits (78), Expect = 0.53 Identities = 41/160 (25%), Positives = 54/160 (33%), Gaps = 25/160 (15%) Query: 291 EGSSAQAVSLSRAQEPAQP--PALTPESAPG--------CTTEFAPGPAPGTEPVPGLEL 340 +GS+ + P P + PE++ TT P+P P P Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871 Query: 341 GLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPL---GDWPALPRRWPLPQ 397 L + V L P P TP + P+P GP Q P L P R P P+ Sbjct: 872 PLSPKGV-TLPPKETP--TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK 928 Query: 398 GWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRP 437 G P S P P A PP+ + G P P Sbjct: 929 GIPASPS---------PKGAPTPPAATPPSPKGGPATPSP 959 Score = 33.9 bits (76), Expect = 0.91 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 6/84 (7%) Query: 1029 QRGAQPLAVAKELA-AVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLT 1087 Q+ + A K+ + + K P P +S ++A F + P P S++ SAA P ++ Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK--PESASVSAAPSPPVS 1799 Query: 1088 MPARP---PSLPPLLLLPPLIPSL 1108 +P P P+LPP P P L Sbjct: 1800 LPLAPSPVPTLPPKQQFLPSSPGL 1823 Score = 33.1 bits (74), Expect = 1.5 Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 20/91 (21%) Query: 296 QAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPG 355 +A + ++E + PPA+TP + G AP P EL L P P P Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKG-----APSPK---------EL---LIPPAVTSPSPK 1611 Query: 356 PSVTPGSLPAPWPVLGP-VPAPGAQP--PPL 383 + TP ++ P P GP PAP P PP+ Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTSPPV 1642 Score = 32.0 bits (71), Expect = 3.4 Identities = 18/69 (26%), Positives = 30/69 (43%) Query: 1073 PRSSACSAASGPHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGR 1132 P+ + +S T+PA P P P + + P++AP + AP + + + Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511 Query: 1133 KPPEEPANP 1141 P E PA P Sbjct: 1512 SPKEVPATP 1520 >gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] Length = 727 Score = 50.1 bits (118), Expect = 1e-05 Identities = 50/196 (25%), Positives = 71/196 (36%), Gaps = 14/196 (7%) Query: 244 VEQLPEAALAQTTKYLEATRA--IQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLS 301 +E P TT L A+ S +P L H + ++ Sbjct: 302 IEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADSP 361 Query: 302 RAQEPAQPPALTPESAPGCTTEFAPGPA-PGTEPVPGLELGLE---LEPVPA--LGPVPG 355 R Q + PA+ SAP T ++ GPA P +P + +PVPA P PG Sbjct: 362 RPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPG 421 Query: 356 PSVTPGSL-PAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLR 414 + +P P+P P P PAP P P+ + P P P P V Sbjct: 422 ANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAP----SVAY 477 Query: 415 PTQP-QPSRAPPPATE 429 P +P+ PP T+ Sbjct: 478 SGGPAEPASRPPWVTD 493 Score = 33.1 bits (74), Expect = 1.5 Identities = 36/116 (31%), Positives = 41/116 (35%), Gaps = 21/116 (18%) Query: 282 HYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLEL- 340 +Y P + A S + A P+ P TP AP T P PAP P P + Sbjct: 423 NYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYT----PSPAPNYNPAPSVAYS 478 Query: 341 GLELEPVPALGPV----------PGPSVTPGS---LPAPWPVLGPVPAPGAQPPPL 383 G EP V PG S T S LP P P G Q PPL Sbjct: 479 GGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPA---GPQVPPL 531 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 50.1 bits (118), Expect = 1e-05 Identities = 60/223 (26%), Positives = 75/223 (33%), Gaps = 16/223 (7%) Query: 248 PEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPA 307 P+A A L+A + S PVQ P + P P SA S + A Sbjct: 650 PQAPNALAVHLLQAPFSPPPSPPVQAP--------FSPPASPPVSPSATPPSQA-PPSLA 700 Query: 308 QPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPW 367 PP P S P P P P L++ P P P PS TP P Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP---PPRV 757 Query: 368 PVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPA 427 P L P P P P P P PQ P + + PL L P+ P P Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL----PSPPASFPGQAPF 813 Query: 428 TEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLR 470 + SL PL + L +QV P+L+ R Sbjct: 814 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 856 Score = 39.7 bits (91), Expect = 0.017 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 18/95 (18%) Query: 1047 PSPPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLTMPARPPSLPPLLLLPPLIP 1106 PSPP Q+ + S + P P S A + + P L +P PP+ PP+ P Sbjct: 669 PSPPVQAPFSPPASPP----VSPSATPPSQAPPSLAAPPLQVPPSPPA------SPPMSP 718 Query: 1107 SLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPANP 1141 S P QAP P + + + PP PA+P Sbjct: 719 SATPPPQAP--------PPLAAPPLQVPPSPPASP 745 Score = 38.5 bits (88), Expect = 0.037 Identities = 42/151 (27%), Positives = 49/151 (32%), Gaps = 14/151 (9%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELE 345 P L P + A P Q P P S P AP V L+ Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668 Query: 346 PVPAL--------GPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQ 397 P P + P PS TP S P P+ P P P P P P PQ Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP---PSPPASPPMSPSATPPPQ 725 Query: 398 GWPRVGSWPLWDLGVLRPTQP--QPSRAPPP 426 P + + PL + P P PS PPP Sbjct: 726 APPPLAAPPL-QVPPSPPASPPMSPSATPPP 755 Score = 36.6 bits (83), Expect = 0.14 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 6/98 (6%) Query: 1049 PPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLTMPAR----PPSLPPLLLLPPL 1104 PP Q+ + + L CP CP + S + P P+ PP PP L PPL Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603 Query: 1105 IPSLRDPQQAPGSTRLSRA-PHIESRVGRKPPEEPANP 1141 L P +P +T +A P + + PP PA+P Sbjct: 604 -QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640 Score = 35.4 bits (80), Expect = 0.31 Identities = 55/205 (26%), Positives = 76/205 (37%), Gaps = 14/205 (6%) Query: 235 SSPLDLW--QSVEQL----PEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYE-VPE 287 SSPL + Q++ L P+A L+ T++ +Q P T E +P Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540 Query: 288 LLPEGSSAQAVSLSRAQEPAQP-PALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEP 346 L P + L+ P PA P AP P P + P + L Sbjct: 541 LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600 Query: 347 VPALGPVPGPSVTPGSLPAPW-PVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSW 405 P G +P P ++P + P P P +P A P P P P P PQ P + Sbjct: 601 PPLQG-LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA-PNALAV 658 Query: 406 PLWDLGVLRPTQPQPSRAP--PPAT 428 L P P P +AP PPA+ Sbjct: 659 HLLQAPFSPPPSP-PVQAPFSPPAS 682 Score = 34.3 bits (77), Expect = 0.69 Identities = 43/135 (31%), Positives = 49/135 (36%), Gaps = 25/135 (18%) Query: 304 QEPAQPPALTPE---SAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGP-VPGPSVT 359 Q P +PP P+ S P T APGP P P L GP + G S + Sbjct: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS---------GPDLAGHSSS 903 Query: 360 PGSLPAPWPVL--GPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQ 417 S P GP A PPP + A P W R + PL G P Sbjct: 904 ATSTPEELRGYDSGPEGGAAASPPPDAELAACH-----PAAWSRGPAPPLAFRGA--PGA 956 Query: 418 PQPSRAPPPATEFGS 432 P P PPAT GS Sbjct: 957 PLPW---PPATGPGS 968 Score = 33.5 bits (75), Expect = 1.2 Identities = 42/157 (26%), Positives = 56/157 (35%), Gaps = 31/157 (19%) Query: 336 PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPL 395 PGL L P P P P P VTP +L VLG A G + PL + + Sbjct: 22 PGL-----LTPRPPGSPRPPPPVTPAAL----RVLGAAGAVGRK--PLAERAGGIGGATI 70 Query: 396 PQGWPRVGSWPLWDLGVLRPTQPQPS-----RAPP-----------PATEFGSLWPRPLQ 439 P+ PR G P P+ RAPP P G+ P PL Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL- 129 Query: 440 PYQSRQGEALQLAAVQVKGEENDVPSLRGLRERARKD 476 ++G + +G+ + P L AR+D Sbjct: 130 ---GQKGLRISAEETVARGKATEAPKRSALSAGARRD 163 Score = 33.1 bits (74), Expect = 1.5 Identities = 39/144 (27%), Positives = 49/144 (34%), Gaps = 24/144 (16%) Query: 308 QPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPW 367 +PP +TP +P P P G + PVP P + TP LPA Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPS---GTKARPVPP----PDNAATP--LPATL 331 Query: 368 PVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPA 427 P P+ P PP P + P P P P+Q PS PP Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP--------------PSQAPPSMTTPPM 377 Query: 428 TEFGSLWP-RPLQPYQSRQGEALQ 450 SL P+Q S +LQ Sbjct: 378 QAPPSLQTIPPIQVPHSLTSPSLQ 401 Score = 32.7 bits (73), Expect = 2.0 Identities = 51/206 (24%), Positives = 68/206 (33%), Gaps = 44/206 (21%) Query: 261 ATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSR--AQEPAQPPALTPESAP 318 A ++Q + + +P L T + + P + A S SR + P PP P S P Sbjct: 408 ALSSLQATTSLGSPTLQAT---HSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464 Query: 319 GCT---TEFAPGPAPGTEPVPGLELGLELEPVPALGPVPG------------------PS 357 T +P +P + P L + P+ AL + S Sbjct: 465 ASPPLQTSLSPAVSPLSSP-------LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSS 517 Query: 358 VTPGSLPAPWPVLGPVPA---PGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLR 414 + P SL P L P P PPPL A P P + P PL Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA-PLTTPHLETPPCPAPCPL------- 569 Query: 415 PTQPQPSRAPPPATEFGSLWPRPLQP 440 P P PPP T P P P Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAP 595 Score = 32.7 bits (73), Expect = 2.0 Identities = 32/116 (27%), Positives = 39/116 (33%), Gaps = 5/116 (4%) Query: 1028 SQRGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCP----RSSACSAASG 1083 S P LAA PPS + SA PPL + AS Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776 Query: 1084 PHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIE-SRVGRKPPEEP 1138 P + PP PP L PPL P PG S + + S + PP+ P Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832 Score = 31.6 bits (70), Expect = 4.5 Identities = 32/106 (30%), Positives = 38/106 (35%), Gaps = 10/106 (9%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAP-----GPAPGTEPVPGLEL 340 P P + A++ Q PPA P AP + P P P PV L Sbjct: 780 PLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 839 Query: 341 GLELEPVPALGPV---PGPSVTPG-SLPAPWPVLGPVPAPGAQPPP 382 L++ P P P P TPG P L APG PPP Sbjct: 840 -LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884 Score = 30.8 bits (68), Expect = 7.7 Identities = 34/124 (27%), Positives = 38/124 (30%), Gaps = 14/124 (11%) Query: 1028 SQRGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPP-------LCPRSSACSA 1080 S P LAA PPS + SA PP P S S Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745 Query: 1081 ASGPHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKP----PE 1136 P T P P +PPLL PPL P P S P + P P Sbjct: 746 PMSPSATPP---PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802 Query: 1137 EPAN 1140 PA+ Sbjct: 803 PPAS 806 >gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 306 Score = 50.1 bits (118), Expect = 1e-05 Identities = 32/113 (28%), Positives = 42/113 (37%), Gaps = 6/113 (5%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L P + S + P+ P LTP S P T P Sbjct: 100 SPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 159 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P + P+ L P L P P++TP S P P P P ++P Sbjct: 160 LTPSSRPI------LTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRP 206 Score = 45.1 bits (105), Expect = 4e-04 Identities = 31/111 (27%), Positives = 38/111 (34%) Query: 270 PVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPA 329 P P T+ P L P S + P+ PP LTP + P T P Sbjct: 8 PTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLT 67 Query: 330 PGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P + P L P P L P++TP S P P P P P Sbjct: 68 PSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTP 118 Score = 43.9 bits (102), Expect = 9e-04 Identities = 30/113 (26%), Positives = 38/113 (33%), Gaps = 6/113 (5%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P + P L P S + P+ P LTP S P T P Sbjct: 140 STPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 199 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P + P+ L P L P P +TP S P P P+ + P Sbjct: 200 LTPSSRPI------LTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTP 246 Score = 42.7 bits (99), Expect = 0.002 Identities = 31/123 (25%), Positives = 40/123 (32%), Gaps = 10/123 (8%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P + P L P + S + P+ P LTP S P T P Sbjct: 156 STPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 215 Query: 328 PAPGTEPV----------PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPG 377 P + P+ P L P L P P++TP + P P P P Sbjct: 216 LTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPS 275 Query: 378 AQP 380 P Sbjct: 276 NTP 278 Score = 42.0 bits (97), Expect = 0.003 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 13/93 (13%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365 P+ P LTP S P T P P ++P+ L P L P P++TP + P Sbjct: 4 PSNTPTLTPSSPPTLTPSSTPTLTPSSQPI------LTRSSTPTLTPSSPPTLTPSNTPT 57 Query: 366 PWPVLGPVPAPGAQP-------PPLGDWPALPR 391 P P P + P P L P L R Sbjct: 58 LTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTR 90 Score = 41.6 bits (96), Expect = 0.004 Identities = 32/113 (28%), Positives = 37/113 (32%), Gaps = 4/113 (3%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P + P L P S + P+ P LTP S P T P Sbjct: 22 STPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLT----PS 77 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P P P L P+ P PS TP P+ P L P P P Sbjct: 78 STPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTP 130 Score = 41.2 bits (95), Expect = 0.006 Identities = 29/113 (25%), Positives = 38/113 (33%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L + S P+ P LTP + P T P Sbjct: 14 SPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPT 73 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P + P + L P L P P++TP + P P P P P Sbjct: 74 LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTP 126 Score = 41.2 bits (95), Expect = 0.006 Identities = 31/115 (26%), Positives = 39/115 (33%), Gaps = 2/115 (1%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L P S + P+ P LTP S P T P Sbjct: 180 STPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPI 239 Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 + P P L P L P P++TP + P P P P + P Sbjct: 240 LTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTP 294 Score = 39.3 bits (90), Expect = 0.022 Identities = 31/101 (30%), Positives = 37/101 (36%), Gaps = 6/101 (5%) Query: 288 LLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEP--VPGLELGLELE 345 L P + S P+ P LTP S P T P P + P P L Sbjct: 2 LTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 61 Query: 346 PVPALGPVPGPSVTPGSLP--APWPVLGPVPAPGAQP--PP 382 P L P P++TP S P P P+L P P PP Sbjct: 62 NTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPP 102 Score = 38.9 bits (89), Expect = 0.028 Identities = 31/113 (27%), Positives = 38/113 (33%), Gaps = 2/113 (1%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L + S P+ P LTP S P T P Sbjct: 188 STPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPT 247 Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGA 378 P + P P L P L P P++TP S P P P P + Sbjct: 248 LTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSS 300 Score = 37.4 bits (85), Expect = 0.082 Identities = 29/113 (25%), Positives = 39/113 (34%), Gaps = 4/113 (3%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S+P+ T+ P L P + +L+ + P P+ TP P T P Sbjct: 30 SQPILTRSSTPTLTPSSPPTLTPSNTP----TLTPSNTPTLTPSSTPTLTPSSTPTLTPQ 85 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P P L P+ P PS TP P+ P L P P P Sbjct: 86 PILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTP 138 Score = 32.3 bits (72), Expect = 2.6 Identities = 24/96 (25%), Positives = 33/96 (34%), Gaps = 14/96 (14%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P+ P T+ P L + S + P+ P LTP + P T P Sbjct: 220 SRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPT 279 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSL 363 P + P L P P++TP SL Sbjct: 280 LTPSS--------------TPTLTPSSTPTLTPSSL 301 >gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 306 Score = 50.1 bits (118), Expect = 1e-05 Identities = 32/113 (28%), Positives = 42/113 (37%), Gaps = 6/113 (5%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L P + S + P+ P LTP S P T P Sbjct: 100 SPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 159 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P + P+ L P L P P++TP S P P P P ++P Sbjct: 160 LTPSSRPI------LTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRP 206 Score = 45.1 bits (105), Expect = 4e-04 Identities = 31/111 (27%), Positives = 38/111 (34%) Query: 270 PVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPA 329 P P T+ P L P S + P+ PP LTP + P T P Sbjct: 8 PTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLT 67 Query: 330 PGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P + P L P P L P++TP S P P P P P Sbjct: 68 PSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTP 118 Score = 43.9 bits (102), Expect = 9e-04 Identities = 30/113 (26%), Positives = 38/113 (33%), Gaps = 6/113 (5%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P + P L P S + P+ P LTP S P T P Sbjct: 140 STPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 199 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P + P+ L P L P P +TP S P P P+ + P Sbjct: 200 LTPSSRPI------LTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTP 246 Score = 42.7 bits (99), Expect = 0.002 Identities = 31/123 (25%), Positives = 40/123 (32%), Gaps = 10/123 (8%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P + P L P + S + P+ P LTP S P T P Sbjct: 156 STPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 215 Query: 328 PAPGTEPV----------PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPG 377 P + P+ P L P L P P++TP + P P P P Sbjct: 216 LTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPS 275 Query: 378 AQP 380 P Sbjct: 276 NTP 278 Score = 42.0 bits (97), Expect = 0.003 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 13/93 (13%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365 P+ P LTP S P T P P ++P+ L P L P P++TP + P Sbjct: 4 PSNTPTLTPSSPPTLTPSSTPTLTPSSQPI------LTRSSTPTLTPSSPPTLTPSNTPT 57 Query: 366 PWPVLGPVPAPGAQP-------PPLGDWPALPR 391 P P P + P P L P L R Sbjct: 58 LTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTR 90 Score = 41.6 bits (96), Expect = 0.004 Identities = 32/113 (28%), Positives = 37/113 (32%), Gaps = 4/113 (3%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P + P L P S + P+ P LTP S P T P Sbjct: 22 STPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLT----PS 77 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P P P L P+ P PS TP P+ P L P P P Sbjct: 78 STPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTP 130 Score = 41.2 bits (95), Expect = 0.006 Identities = 29/113 (25%), Positives = 38/113 (33%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L + S P+ P LTP + P T P Sbjct: 14 SPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPT 73 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P + P + L P L P P++TP + P P P P P Sbjct: 74 LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTP 126 Score = 41.2 bits (95), Expect = 0.006 Identities = 31/115 (26%), Positives = 39/115 (33%), Gaps = 2/115 (1%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L P S + P+ P LTP S P T P Sbjct: 180 STPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPI 239 Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 + P P L P L P P++TP + P P P P + P Sbjct: 240 LTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTP 294 Score = 39.3 bits (90), Expect = 0.022 Identities = 31/101 (30%), Positives = 37/101 (36%), Gaps = 6/101 (5%) Query: 288 LLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEP--VPGLELGLELE 345 L P + S P+ P LTP S P T P P + P P L Sbjct: 2 LTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 61 Query: 346 PVPALGPVPGPSVTPGSLP--APWPVLGPVPAPGAQP--PP 382 P L P P++TP S P P P+L P P PP Sbjct: 62 NTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPP 102 Score = 38.9 bits (89), Expect = 0.028 Identities = 31/113 (27%), Positives = 38/113 (33%), Gaps = 2/113 (1%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L + S P+ P LTP S P T P Sbjct: 188 STPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPT 247 Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGA 378 P + P P L P L P P++TP S P P P P + Sbjct: 248 LTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSS 300 Score = 37.4 bits (85), Expect = 0.082 Identities = 29/113 (25%), Positives = 39/113 (34%), Gaps = 4/113 (3%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S+P+ T+ P L P + +L+ + P P+ TP P T P Sbjct: 30 SQPILTRSSTPTLTPSSPPTLTPSNTP----TLTPSNTPTLTPSSTPTLTPSSTPTLTPQ 85 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P P L P+ P PS TP P+ P L P P P Sbjct: 86 PILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTP 138 Score = 32.3 bits (72), Expect = 2.6 Identities = 24/96 (25%), Positives = 33/96 (34%), Gaps = 14/96 (14%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P+ P T+ P L + S + P+ P LTP + P T P Sbjct: 220 SRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPT 279 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSL 363 P + P L P P++TP SL Sbjct: 280 LTPSS--------------TPTLTPSSTPTLTPSSL 301 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 50.1 bits (118), Expect = 1e-05 Identities = 62/208 (29%), Positives = 80/208 (38%), Gaps = 44/208 (21%) Query: 293 SSAQAVSLSRAQEPAQPPA------------LTPESAPGCTTEFAPGPAPG----TEPVP 336 SS Q+V L + A PA + P+S P P APG + P P Sbjct: 630 SSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAP 689 Query: 337 GLELGLELE-PVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPR-RWP 394 L+ P PA+ P + P S P P P P PG QPPPL LP+ P Sbjct: 690 ACPPSLQQHFPDPAMSFAP--VLPPPSTPMPTGPGQPAP-PGQQPPPLAQPTPLPQVLAP 746 Query: 395 LPQGWPRVGSWPLWDLGVLRPTQPQPSRAPP---PATEFGSLWPRPLQPYQSRQGEALQL 451 P + P QP P PP PA++ G+ P L+P Q Q L Sbjct: 747 QP----------------VVPLQPVPPHLPPYLAPASQVGA--PAQLKPLQMPQAPLQPL 788 Query: 452 AAVQVKGEENDVPSLRGLRERARKDGAP 479 A QV + +P + + A DG P Sbjct: 789 A--QVPPQMPPIPVVPPITPLAGIDGLP 814 Score = 44.3 bits (103), Expect = 7e-04 Identities = 55/174 (31%), Positives = 66/174 (37%), Gaps = 42/174 (24%) Query: 290 PEGSSAQAVSLSRAQEPAQP--PALTPESAPGCTTEFAPGP------------APGTEPV 335 P G +A ++ + AQ P QP PA P+ AP T+ P P P P Sbjct: 891 PPGVAALSIHSAVAQLPGQPVYPAAFPQMAP---TDVPPSPHHTVQNMRATPPQPALPPQ 947 Query: 336 PGLELGLELEPVPALGPVP----------GPSVTPGSLPAPWPVLGPVPAPGAQPPPLGD 385 P L L P P L P P P + P + P PVL P PA +P PL Sbjct: 948 PTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPL-- 1005 Query: 386 WPALPRRWPLPQGWPRVGSWPLW--------DLGVLRPTQPQPSRA--PPPATE 429 P LP + P P GS L D+ PT P P A PP E Sbjct: 1006 QPHLPEQ-AAPAATP--GSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPE 1056 Score = 38.5 bits (88), Expect = 0.037 Identities = 38/134 (28%), Positives = 52/134 (38%), Gaps = 21/134 (15%) Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELE 345 P LP+ + Q V + P PP L P S G + P P P ++ ++ Sbjct: 737 PTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMP 796 Query: 346 PVPALGPV---PGPSVTPGSLP-APWPVLGPVPAP------------GAQPPPLGDWPAL 389 P+P + P+ G P +LP P + PVP P A PP PAL Sbjct: 797 PIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPAS--PAL 854 Query: 390 PR---RWPLPQGWP 400 P + P P G P Sbjct: 855 PLQAVKLPHPPGAP 868 Score = 32.0 bits (71), Expect = 3.4 Identities = 32/93 (34%), Positives = 41/93 (44%), Gaps = 12/93 (12%) Query: 290 PEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPA 349 PE +S + S R EP PPA PE +P T P PA G +P P L + + A Sbjct: 1460 PEAASTRDASAPR--EPLPPPA--PEPSPHSGT---PQPALG-QPAPLLPAAVGAVSL-A 1510 Query: 350 LGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382 +P P + P P P L + G PPP Sbjct: 1511 TSQLPSPPLGPTVPPQPPSAL---ESDGEGPPP 1540 Score = 31.2 bits (69), Expect = 5.9 Identities = 38/140 (27%), Positives = 46/140 (32%), Gaps = 25/140 (17%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365 P PPA S+P T G AP T +P EP G TP L + Sbjct: 1377 PGAPPAPLAPSSPPVTALPQDGAAPATSTMP--------EPASGTASQAGGPGTPQGLTS 1428 Query: 366 PWPVLGPV----PAP-GAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQP 420 P+ AP QP +G P P P S P +P P Sbjct: 1429 ELETSQPLAETHEAPLAVQPLVVGLAPCTPA--------PEAAS----TRDASAPREPLP 1476 Query: 421 SRAPPPATEFGSLWPRPLQP 440 AP P+ G+ P QP Sbjct: 1477 PPAPEPSPHSGTPQPALGQP 1496 >gi|50428940 mediator complex subunit 25 [Homo sapiens] Length = 747 Score = 49.7 bits (117), Expect = 2e-05 Identities = 47/140 (33%), Positives = 57/140 (40%), Gaps = 25/140 (17%) Query: 278 QTVWHYEVPELLPEGS--SAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPV 335 Q + P+ P+G+ ++ A + Q AQPP P+ PG + P P P P Sbjct: 580 QNLLQLRPPQPQPQGTVGASGATGQPQPQGTAQPPPGAPQGPPGAASG-PPPPGPILRPQ 638 Query: 336 -PGLE---LGLELEPVPALGPVPGPSVT---------PGSLPAP-----WPVLGPVPAPG 377 PG L L P P VP P + P LP P P LGP P Sbjct: 639 NPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGP---PL 695 Query: 378 AQPPPLGDWPA-LPRRWPLP 396 PPP WPA LP R PLP Sbjct: 696 LHPPPAQSWPAQLPPRAPLP 715 Score = 37.4 bits (85), Expect = 0.082 Identities = 47/154 (30%), Positives = 61/154 (39%), Gaps = 31/154 (20%) Query: 234 GSSPLDLWQSVEQLPEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGS 293 GS+P L QS + +P A + L A A Q P PQ Y+VP L Sbjct: 233 GSAPGPL-QSKQPVPLPPAAPSGATLSA--APQQPLPPVPPQ-------YQVPGNLSAAQ 282 Query: 294 SA--QAVSLSRAQEPAQPPALTP-----ESAPGCTTEFAPGPAPGTEPVPGLELGLELEP 346 A AV ++ Q+ P +P ++APG F+ PAP +L P Sbjct: 283 VAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPAP------------QLPP 330 Query: 347 VPALGPVPGPSVTPG--SLPAPWPVLGPVPAPGA 378 P P P P+ P S AP L P PGA Sbjct: 331 GPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGA 364 Score = 36.6 bits (83), Expect = 0.14 Identities = 35/111 (31%), Positives = 44/111 (39%), Gaps = 14/111 (12%) Query: 286 PELLPE--GSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLE 343 P L P+ G++ Q SL P Q P+++ P AP P P LG Sbjct: 633 PILRPQNPGANPQLRSLLLNPPPPQTGVPPPQAS---LHHLQPPGAPALLPPPHQGLGQP 689 Query: 344 LEPVPALGPVPG---PSVTPGSLPAPWPVL------GPVPAPGAQPPPLGD 385 P L P P P+ P P P +L GPVP PG QP + D Sbjct: 690 QLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMED 740 Score = 32.0 bits (71), Expect = 3.4 Identities = 30/111 (27%), Positives = 39/111 (35%), Gaps = 8/111 (7%) Query: 274 PQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTE 333 P LQ+ +P P G++ LS A + PP PG + E Sbjct: 236 PGPLQSKQPVPLPPAAPSGAT-----LSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVE 290 Query: 334 PVPGLELGL--ELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382 + GL P+ L P V P AP P L P P +PPP Sbjct: 291 AAKNQKAGLGPRFSPITPLQQA-APGVGPPFSQAPAPQLPPGPPGAPKPPP 340 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 49.7 bits (117), Expect = 2e-05 Identities = 76/310 (24%), Positives = 114/310 (36%), Gaps = 60/310 (19%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPG---------- 355 P PP + P S P P P T P PG+ + +P P PG Sbjct: 531 PTMPPPVLPPSLP---PPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGP 587 Query: 356 -PSVTPGSLPA--PWPVLGPVPAPGAQPPPLGDWPALPRRWP--------LPQGW-PRVG 403 P + P SL + P PVL P PPP+ P L P +PQG P++ Sbjct: 588 PPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLT 647 Query: 404 SWPLWDLGVLR----PTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGE 459 + P+ + P +P+P+ P P + FGS P P G + Q+ + + Sbjct: 648 AAPVPPASSSQSSQVPEKPRPALLPTPVS-FGSAPPTTYHPPLQSAGPSEQVNSKAPLSK 706 Query: 460 E----NDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDP-------KDRAHKDDV 508 + S +GL E + P T +P GG DP R + D Sbjct: 707 SALPYSSFSSDQGLGESSAAPSQP--ITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDG 764 Query: 509 PK---DRGGKDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEAQ-------PKAPQ 558 P+ D G + P+ + P+ G + P+ R +G P E P+ P Sbjct: 765 PRRFEDLGSRCEGPRPKG-----PRFEGNRPDGPRPRY--EGHPAEGTKSKWGMIPRGPA 817 Query: 559 SALHRLKTTA 568 S + +T+ Sbjct: 818 SQFYITPSTS 827 Score = 44.3 bits (103), Expect = 7e-04 Identities = 43/153 (28%), Positives = 57/153 (37%), Gaps = 37/153 (24%) Query: 295 AQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVP 354 AQ L + + L P P P P P +PG G P P + P P Sbjct: 59 AQLQQLQQMHQKQMQCVLQPHHLP-------PPPLPPPPVMPGGGYGDWQPPPPPMPPPP 111 Query: 355 GPSVT-------------------PGSLPAPW---PVLGPVPAPGAQPPPLGDWPALPRR 392 GP+++ PG +P P PVP PG+ PP + +P Sbjct: 112 GPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVP-PGSYMPPSQSY--MPPP 168 Query: 393 WPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPP 425 P P +P S P L P QP PS++PP Sbjct: 169 QPPPSYYPPTSSQP-----YLPPAQPSPSQSPP 196 Score = 38.1 bits (87), Expect = 0.048 Identities = 33/101 (32%), Positives = 39/101 (38%), Gaps = 7/101 (6%) Query: 353 VPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGV 412 +P P V +P P P + P P + PPP+ PALP P P G P P V Sbjct: 516 MPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMP-PALPATVP-PPGMPPPVMPPSLPTSV 573 Query: 413 LRPTQPQ--PSRAPPPA---TEFGSLWPRPLQPYQSRQGEA 448 P P S PPP S P P+ P S A Sbjct: 574 PPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTA 614 Score = 37.7 bits (86), Expect = 0.063 Identities = 60/256 (23%), Positives = 89/256 (34%), Gaps = 51/256 (19%) Query: 330 PGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA---------PWPVLGPVPAPGAQP 380 PG P PG P P +G PG V P + PA P P+ P P P P Sbjct: 1503 PGMYPPPG-----SYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPP 1557 Query: 381 PPLGDWPAL-PRRWPLPQ-GWPRVGSWPLWDLGVLRPTQ----------PQPSRAPPPAT 428 PP P + P+ + Q W + LWD + P PPP Sbjct: 1558 PP----PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPV 1613 Query: 429 EFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLR------GLRERARKDGAPKDR 482 P P+ + + G D+ + + G R R D P+ Sbjct: 1614 HSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERS 1673 Query: 483 T-------RKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGGK 535 T ++D ++R D +P + + R K +DR D +DRG Sbjct: 1674 TFETEHAGQRDRYDRER---DREPYFDRQSNVIADHRDFK----RDRETHRDRDRDRGVI 1726 Query: 536 DGDPKDRVGKDGAPKE 551 D D +DR ++ P++ Sbjct: 1727 DYD-RDRFDRERRPRD 1741 Score = 34.3 bits (77), Expect = 0.69 Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 17/83 (20%) Query: 1069 PPLCPRSSACSAASGPHLTMPARPPSL-----PPLLLLPPL--------IPSLRDPQQAP 1115 PP+ P S SA GP +P PPSL PP++ LPPL IP PQ P Sbjct: 588 PPVLPPPSLSSA--GPPPVLP--PPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIP 643 Query: 1116 GSTRLSRAPHIESRVGRKPPEEP 1138 + P S + PE+P Sbjct: 644 PQLTAAPVPPASSSQSSQVPEKP 666 Score = 30.8 bits (68), Expect = 7.7 Identities = 53/198 (26%), Positives = 70/198 (35%), Gaps = 31/198 (15%) Query: 339 ELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP---PPLGDWPALPRRWPL 395 E GL E +P V P P PV +P PG P PP+ P + + Sbjct: 1588 EQGLNSEFKSETAAIPSAPVLP-----PPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDY 1642 Query: 396 PQGWP----RVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSL----WPRPLQPYQSRQGE 447 G +V P + LRP P P R+ G R +PY RQ Sbjct: 1643 GHGRDISTNKVEQIPYGERITLRP-DPLPERSTFETEHAGQRDRYDRERDREPYFDRQSN 1701 Query: 448 ALQLAAVQVKGEEN--DVPSLRGL----RERARKDGAPKD------RTRKDGVPKDRGGK 495 + + E D RG+ R+R ++ P+D R +KD RGG Sbjct: 1702 VIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQSYRDKKDHSSSRRGGF 1761 Query: 496 DVDPKDRAHKDDVPKDRG 513 D DR K D P G Sbjct: 1762 DRPSYDR--KSDRPVYEG 1777 >gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] Length = 280 Score = 48.9 bits (115), Expect = 3e-05 Identities = 33/115 (28%), Positives = 41/115 (35%), Gaps = 2/115 (1%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L P + S + P+ P LTP S P T P Sbjct: 114 STPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 173 Query: 328 PAPGTEP--VPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P + P P L P L P P++TP S P P P P + P Sbjct: 174 LTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTP 228 Score = 48.5 bits (114), Expect = 4e-05 Identities = 33/115 (28%), Positives = 42/115 (36%), Gaps = 2/115 (1%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L P + S + P+ P LTP S P T P Sbjct: 74 STPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 133 Query: 328 PAPGTEPVPGLELGLELEP--VPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P + P L P P L P P++TP S P P P P ++P Sbjct: 134 LTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRP 188 Score = 45.4 bits (106), Expect = 3e-04 Identities = 31/115 (26%), Positives = 41/115 (35%), Gaps = 2/115 (1%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L + S + P+ P LTP S P T P Sbjct: 122 STPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 181 Query: 328 PAPGTEPVPGLELGLELEP--VPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P + P+ L P P L P P++TP + P P P P + P Sbjct: 182 LTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTP 236 Score = 45.1 bits (105), Expect = 4e-04 Identities = 33/123 (26%), Positives = 41/123 (33%), Gaps = 10/123 (8%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L P + S + P+ P LTP S P T P Sbjct: 58 SPPTLTPSNTPTLTPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPT 117 Query: 328 PAPGTEP----------VPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPG 377 P + P P L P L P P++TP S P P P P Sbjct: 118 LTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPS 177 Query: 378 AQP 380 + P Sbjct: 178 STP 180 Score = 44.3 bits (103), Expect = 7e-04 Identities = 31/115 (26%), Positives = 40/115 (34%), Gaps = 2/115 (1%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L P + S + P+ P LTP S P T P Sbjct: 130 STPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPI 189 Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 + P P L P L P P++ P S P P P P ++P Sbjct: 190 LTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRP 244 Score = 42.0 bits (97), Expect = 0.003 Identities = 30/117 (25%), Positives = 40/117 (34%), Gaps = 2/117 (1%) Query: 266 QVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFA 325 ++ P P T+ P L P + + P+ P LTP S P T Sbjct: 48 EMGTPTLTPSSPPTLTPSNTPTLTPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSST 107 Query: 326 PGPAPGTEP--VPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380 P P + P P L P L P P++T S P P P P + P Sbjct: 108 PTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTP 164 Score = 41.2 bits (95), Expect = 0.006 Identities = 33/119 (27%), Positives = 41/119 (34%), Gaps = 6/119 (5%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L P + S + P+ P LT S P T P Sbjct: 146 STPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPT 205 Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLP----APWPVLGPVPAPGAQP 380 P + P P L P L P P++TP S P + P L P P P Sbjct: 206 LTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTP 264 Score = 40.8 bits (94), Expect = 0.007 Identities = 27/101 (26%), Positives = 34/101 (33%), Gaps = 6/101 (5%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P + P L P + S + P+ P L P S P T P Sbjct: 178 STPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPT 237 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWP 368 P + P L P L P P++TP S P P Sbjct: 238 LTPSSRPT------LTRSSTPTLTPSSTPTLTPSSTPTLTP 272 Score = 37.0 bits (84), Expect = 0.11 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 14/96 (14%) Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327 S P P T+ P L P + S + P+ P LTP S P T P Sbjct: 194 STPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPT 253 Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSL 363 P + P L P P++TP SL Sbjct: 254 LTPSS--------------TPTLTPSSTPTLTPSSL 275 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 48.9 bits (115), Expect = 3e-05 Identities = 45/180 (25%), Positives = 62/180 (34%), Gaps = 5/180 (2%) Query: 306 PAQPPAL---TPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGS 362 PA+PP TP+ +P APG P + G P GP + G Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466 Query: 363 LPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSR 422 P + GP P QP P P P P P P G +P+ QP Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526 Query: 423 APPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDV--PSLRGLRERARKDGAPK 480 PP+ + GS P QP ++ V G + P++ ++ G PK Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586 Score = 48.5 bits (114), Expect = 4e-05 Identities = 65/262 (24%), Positives = 85/262 (32%), Gaps = 38/262 (14%) Query: 303 AQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALG------PVPGP 356 A+ PAQP LT A T P PGT P LG P G PGP Sbjct: 329 AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388 Query: 357 SV---TPGSLPAPWPVLGPVPAPGAQ---PPPLGDWPAL--------PRRWPLPQGWP-- 400 PG P GP P Q P PL P L P + P+ Q P Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448 Query: 401 ------RVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAV 454 G G +P P A PP + G P P QP ++ Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS------- 501 Query: 455 QVKGEENDVPSLRG-LRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDR- 512 Q G P G + ++ G+ K +++ G K + K A + P + Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561 Query: 513 -GGKDVDPKDRAHKDDVPKDRG 533 GK + P + P +G Sbjct: 562 GSGKPLQPPTVSPSAKQPPSQG 583 Score = 42.7 bits (99), Expect = 0.002 Identities = 42/159 (26%), Positives = 56/159 (35%), Gaps = 23/159 (14%) Query: 289 LPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVP 348 L + A + + Q+P ++ PG T+ GP +PG +P Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP-- 484 Query: 349 ALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLW 408 GP P PGS P G P QP P P P P P Sbjct: 485 --GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP-------- 534 Query: 409 DLGVLRPTQPQPSRAPP-------PATEFGSLWPRPLQP 440 G +P+ QPS A P P ++ GS +PLQP Sbjct: 535 --GSAKPSAQQPSPAKPSAQQSTKPVSQTGS--GKPLQP 569 Score = 40.8 bits (94), Expect = 0.007 Identities = 65/269 (24%), Positives = 91/269 (33%), Gaps = 40/269 (14%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365 P +PPA P PGPA GL L +P G V P PG+ Sbjct: 311 PGKPPAQQPGHEKS-----QPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQPPGTTKP 361 Query: 366 PWPVLGPVPAPGAQ---PPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSR 422 P LGP P Q P + P P+ P P VG P QP Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPG-PKALAQP---PGVGKTP----------AQQPGP 407 Query: 423 APPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEE---NDVPSLRG--LRERARKDG 477 A PP + G+ P+PL Q A + ++ +P+ + + A++ G Sbjct: 408 AKPPTQQVGT--PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465 Query: 478 APKDRTRKDG---VPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGG 534 K ++ G P + G P + P + G P + + G Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525 Query: 535 KDGDPKDRVG--KDGA--PKEAQPKAPQS 559 P + G K A P A+P A QS Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQS 554 Score = 36.6 bits (83), Expect = 0.14 Identities = 56/238 (23%), Positives = 81/238 (34%), Gaps = 26/238 (10%) Query: 225 HDAMFTSEIGSSPLDLWQSVEQLPEAALAQTTKYLEATRAIQVSEPVQ-------NPQLL 277 H + S++ SS ++ SV PE +A T + I +PV+ N +L Sbjct: 2261 HIVISLSDMASSIIE---SVVPKPEGPVADT---VSTDLLISEKDPVKKAKKETGNGIIL 2314 Query: 278 QTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPG 337 + + Y + L + ++S + P P TT F G G E P Sbjct: 2315 EVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEK-PA 2373 Query: 338 LELGLELEPVPALGPVPGPSVTPGSL------------PAPWPVLGPVPAPGAQPPPLGD 385 +L V +L P P SL P P P P P P PPP Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433 Query: 386 WPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQS 443 P + + L P + PL+D T P T + P P+ P S Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 48.9 bits (115), Expect = 3e-05 Identities = 45/180 (25%), Positives = 62/180 (34%), Gaps = 5/180 (2%) Query: 306 PAQPPAL---TPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGS 362 PA+PP TP+ +P APG P + G P GP + G Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466 Query: 363 LPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSR 422 P + GP P QP P P P P P P G +P+ QP Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526 Query: 423 APPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDV--PSLRGLRERARKDGAPK 480 PP+ + GS P QP ++ V G + P++ ++ G PK Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586 Score = 48.5 bits (114), Expect = 4e-05 Identities = 65/262 (24%), Positives = 85/262 (32%), Gaps = 38/262 (14%) Query: 303 AQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALG------PVPGP 356 A+ PAQP LT A T P PGT P LG P G PGP Sbjct: 329 AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388 Query: 357 SV---TPGSLPAPWPVLGPVPAPGAQ---PPPLGDWPAL--------PRRWPLPQGWP-- 400 PG P GP P Q P PL P L P + P+ Q P Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448 Query: 401 ------RVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAV 454 G G +P P A PP + G P P QP ++ Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS------- 501 Query: 455 QVKGEENDVPSLRG-LRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDR- 512 Q G P G + ++ G+ K +++ G K + K A + P + Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561 Query: 513 -GGKDVDPKDRAHKDDVPKDRG 533 GK + P + P +G Sbjct: 562 GSGKPLQPPTVSPSAKQPPSQG 583 Score = 42.7 bits (99), Expect = 0.002 Identities = 42/159 (26%), Positives = 56/159 (35%), Gaps = 23/159 (14%) Query: 289 LPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVP 348 L + A + + Q+P ++ PG T+ GP +PG +P Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP-- 484 Query: 349 ALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLW 408 GP P PGS P G P QP P P P P P Sbjct: 485 --GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP-------- 534 Query: 409 DLGVLRPTQPQPSRAPP-------PATEFGSLWPRPLQP 440 G +P+ QPS A P P ++ GS +PLQP Sbjct: 535 --GSAKPSAQQPSPAKPSAQQSTKPVSQTGS--GKPLQP 569 Score = 40.8 bits (94), Expect = 0.007 Identities = 65/269 (24%), Positives = 91/269 (33%), Gaps = 40/269 (14%) Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365 P +PPA P PGPA GL L +P G V P PG+ Sbjct: 311 PGKPPAQQPGHEKS-----QPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQPPGTTKP 361 Query: 366 PWPVLGPVPAPGAQ---PPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSR 422 P LGP P Q P + P P+ P P VG P QP Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPG-PKALAQP---PGVGKTP----------AQQPGP 407 Query: 423 APPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEE---NDVPSLRG--LRERARKDG 477 A PP + G+ P+PL Q A + ++ +P+ + + A++ G Sbjct: 408 AKPPTQQVGT--PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465 Query: 478 APKDRTRKDG---VPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGG 534 K ++ G P + G P + P + G P + + G Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525 Query: 535 KDGDPKDRVG--KDGA--PKEAQPKAPQS 559 P + G K A P A+P A QS Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQS 554 Score = 36.6 bits (83), Expect = 0.14 Identities = 56/238 (23%), Positives = 81/238 (34%), Gaps = 26/238 (10%) Query: 225 HDAMFTSEIGSSPLDLWQSVEQLPEAALAQTTKYLEATRAIQVSEPVQ-------NPQLL 277 H + S++ SS ++ SV PE +A T + I +PV+ N +L Sbjct: 2261 HIVISLSDMASSIIE---SVVPKPEGPVADT---VSTDLLISEKDPVKKAKKETGNGIIL 2314 Query: 278 QTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPG 337 + + Y + L + ++S + P P TT F G G E P Sbjct: 2315 EVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEK-PA 2373 Query: 338 LELGLELEPVPALGPVPGPSVTPGSL------------PAPWPVLGPVPAPGAQPPPLGD 385 +L V +L P P SL P P P P P P PPP Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433 Query: 386 WPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQS 443 P + + L P + PL+D T P T + P P+ P S Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 48.9 bits (115), Expect = 3e-05 Identities = 54/186 (29%), Positives = 62/186 (33%), Gaps = 35/186 (18%) Query: 266 QVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPP--ALTPESAPGCTTE 323 Q P Q P Q H P P + Q+P PP + P A G Sbjct: 69 QQQPPPQQPPPQQPPPHQPPPHPQPH----------QQQQPPPPPQDSSKPVVAQG---- 114 Query: 324 FAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGA----- 378 PGPAPG P P G PG PG P P P + P PGA Sbjct: 115 --PGPAPGVGSAPPASSSAPPATPPTSGAPPGSG--PGPTPTPPPAVTSAP-PGAPPPTP 169 Query: 379 -------QPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFG 431 PP G P P P P P+ G P G P P+P P +T G Sbjct: 170 PSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGG 229 Query: 432 SLWPRP 437 P+P Sbjct: 230 H--PKP 233 Score = 36.2 bits (82), Expect = 0.18 Identities = 31/90 (34%), Positives = 35/90 (38%), Gaps = 11/90 (12%) Query: 293 SSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGP 352 SS + +A P PPA P PGP P P PG G ++ P G Sbjct: 171 SSGVPTTPPQAGGPPPPPAAVP----------GPGPGPKQGPGPGGPKGGKMPGGPKPGG 220 Query: 353 VPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382 PG S TPG P P G P G Q P Sbjct: 221 GPGLS-TPGGHPKPPHRGGGEPRGGRQHHP 249 Score = 33.5 bits (75), Expect = 1.2 Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 9/102 (8%) Query: 334 PVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRW 393 P PG+ L P +GP PG S +P P P P QPPP P P Sbjct: 34 PPPGMGLNQNRGP---MGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPH 90 Query: 394 PLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWP 435 P P + P ++P ++ P PA GS P Sbjct: 91 PQPHQQQQPPPPP------QDSSKPVVAQGPGPAPGVGSAPP 126 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 49,317,396 Number of Sequences: 37866 Number of extensions: 2914677 Number of successful extensions: 23652 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 168 Number of HSP's successfully gapped in prelim test: 1102 Number of HSP's that attempted gapping in prelim test: 14641 Number of HSP's gapped (non-prelim): 6230 length of query: 1141 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1028 effective length of database: 13,968,660 effective search space: 14359782480 effective search space used: 14359782480 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.