Guide to the Human Genome
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Search of human proteins with 222446620

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222446620 hypothetical protein LOC342346 [Homo sapiens]
         (1141 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222446620 hypothetical protein LOC342346 [Homo sapiens]           2282   0.0  
gi|14149793 glutamine rich 2 [Homo sapiens]                           107   6e-23
gi|24307909 ral guanine nucleotide dissociation stimulator isofo...    62   2e-09
gi|108796058 ral guanine nucleotide dissociation stimulator isof...    62   2e-09
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    62   3e-09
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    62   3e-09
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    62   3e-09
gi|11386183 WAS protein family, member 2 [Homo sapiens]                60   1e-08
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 58   4e-08
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     57   1e-07
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    56   2e-07
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]               56   2e-07
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 55   5e-07
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    54   8e-07
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...    52   4e-06
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    52   4e-06
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    52   4e-06
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    50   9e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    50   9e-06
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              50   1e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    50   1e-05
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    50   1e-05
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    50   1e-05
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       50   1e-05
gi|50428940 mediator complex subunit 25 [Homo sapiens]                 50   2e-05
gi|146134388 YLP motif containing 1 [Homo sapiens]                     50   2e-05
gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]            49   3e-05
gi|150170670 piccolo isoform 2 [Homo sapiens]                          49   3e-05
gi|150378539 piccolo isoform 1 [Homo sapiens]                          49   3e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    49   3e-05

>gi|222446620 hypothetical protein LOC342346 [Homo sapiens]
          Length = 1141

 Score = 2282 bits (5913), Expect = 0.0
 Identities = 1141/1141 (100%), Positives = 1141/1141 (100%)

Query: 1    MSFSLTFTELANIAIPQCGVLNFKALHLLLHGILEHIHMAELKKVLSGDEDFLQTSQVVI 60
            MSFSLTFTELANIAIPQCGVLNFKALHLLLHGILEHIHMAELKKVLSGDEDFLQTSQVVI
Sbjct: 1    MSFSLTFTELANIAIPQCGVLNFKALHLLLHGILEHIHMAELKKVLSGDEDFLQTSQVVI 60

Query: 61   MPREGDAQPILNPMKRLSNVFDHVVSRLDKLENQLALLQDLPSTAQLLEASQGTARPVQD 120
            MPREGDAQPILNPMKRLSNVFDHVVSRLDKLENQLALLQDLPSTAQLLEASQGTARPVQD
Sbjct: 61   MPREGDAQPILNPMKRLSNVFDHVVSRLDKLENQLALLQDLPSTAQLLEASQGTARPVQD 120

Query: 121  LWHLIKLRKMVEGHDEVMAKSMQTLQDLLTDLHALQVTITALRKEVDMLKNMLDKVHPER 180
            LWHLIKLRKMVEGHDEVMAKSMQTLQDLLTDLHALQVTITALRKEVDMLKNMLDKVHPER
Sbjct: 121  LWHLIKLRKMVEGHDEVMAKSMQTLQDLLTDLHALQVTITALRKEVDMLKNMLDKVHPER 180

Query: 181  MDIFAEDFKIQNWKMVALQREVASLQNKFKTIPKTEDMVLWSGLHDAMFTSEIGSSPLDL 240
            MDIFAEDFKIQNWKMVALQREVASLQNKFKTIPKTEDMVLWSGLHDAMFTSEIGSSPLDL
Sbjct: 181  MDIFAEDFKIQNWKMVALQREVASLQNKFKTIPKTEDMVLWSGLHDAMFTSEIGSSPLDL 240

Query: 241  WQSVEQLPEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSL 300
            WQSVEQLPEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSL
Sbjct: 241  WQSVEQLPEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSL 300

Query: 301  SRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTP 360
            SRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTP
Sbjct: 301  SRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTP 360

Query: 361  GSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQP 420
            GSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQP
Sbjct: 361  GSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQP 420

Query: 421  SRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLRERARKDGAPK 480
            SRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLRERARKDGAPK
Sbjct: 421  SRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLRERARKDGAPK 480

Query: 481  DRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGGKDGDPK 540
            DRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGGKDGDPK
Sbjct: 481  DRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGGKDGDPK 540

Query: 541  DRVGKDGAPKEAQPKAPQSALHRLKTTAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAP 600
            DRVGKDGAPKEAQPKAPQSALHRLKTTAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAP
Sbjct: 541  DRVGKDGAPKEAQPKAPQSALHRLKTTAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAP 600

Query: 601  ATKMAAIATDTAAAGPLGVFADVLGAGPSRGATESQILGDDSEIYEILSPSYSAASIGPD 660
            ATKMAAIATDTAAAGPLGVFADVLGAGPSRGATESQILGDDSEIYEILSPSYSAASIGPD
Sbjct: 601  ATKMAAIATDTAAAGPLGVFADVLGAGPSRGATESQILGDDSEIYEILSPSYSAASIGPD 660

Query: 661  PALSQAMVATKQAMSPEDKKRAVKYSMSHIAQIPVKHDSLKEEFAQLSCNLNQRLSYLAN 720
            PALSQAMVATKQAMSPEDKKRAVKYSMSHIAQIPVKHDSLKEEFAQLSCNLNQRLSYLAN
Sbjct: 661  PALSQAMVATKQAMSPEDKKRAVKYSMSHIAQIPVKHDSLKEEFAQLSCNLNQRLSYLAN 720

Query: 721  MGGPSSLGTTVDILQKKIGSLQKSRLKEEELERIWGNQIEMMKDRYITLDKAVENLQIRM 780
            MGGPSSLGTTVDILQKKIGSLQKSRLKEEELERIWGNQIEMMKDRYITLDKAVENLQIRM
Sbjct: 721  MGGPSSLGTTVDILQKKIGSLQKSRLKEEELERIWGNQIEMMKDRYITLDKAVENLQIRM 780

Query: 781  DEFKTLQAQIKRLEMNKVNKSTMEEELREKADRSALAGKASRVDLETVALELNEMIQGIL 840
            DEFKTLQAQIKRLEMNKVNKSTMEEELREKADRSALAGKASRVDLETVALELNEMIQGIL
Sbjct: 781  DEFKTLQAQIKRLEMNKVNKSTMEEELREKADRSALAGKASRVDLETVALELNEMIQGIL 840

Query: 841  FKVTIHEDSWKKAMEELSKDVNTKLVHSDLDPLKKEMEEVWKIVRKLLIEGLRLDPDSAA 900
            FKVTIHEDSWKKAMEELSKDVNTKLVHSDLDPLKKEMEEVWKIVRKLLIEGLRLDPDSAA
Sbjct: 841  FKVTIHEDSWKKAMEELSKDVNTKLVHSDLDPLKKEMEEVWKIVRKLLIEGLRLDPDSAA 900

Query: 901  GFRRKLFKRVKCISCDRPVEMMTGPQLITIRKAHLLSRLRPASANSCEYLQRQQMREQQW 960
            GFRRKLFKRVKCISCDRPVEMMTGPQLITIRKAHLLSRLRPASANSCEYLQRQQMREQQW
Sbjct: 901  GFRRKLFKRVKCISCDRPVEMMTGPQLITIRKAHLLSRLRPASANSCEYLQRQQMREQQW 960

Query: 961  LQLQDLGIQEDCQQDWGDGPQNATSLKCKSCNLLTLYPYGDPHVIDYDSAEVDILGVDGI 1020
            LQLQDLGIQEDCQQDWGDGPQNATSLKCKSCNLLTLYPYGDPHVIDYDSAEVDILGVDGI
Sbjct: 961  LQLQDLGIQEDCQQDWGDGPQNATSLKCKSCNLLTLYPYGDPHVIDYDSAEVDILGVDGI 1020

Query: 1021 LYKGRVNSQRGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSA 1080
            LYKGRVNSQRGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSA
Sbjct: 1021 LYKGRVNSQRGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSA 1080

Query: 1081 ASGPHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPAN 1140
            ASGPHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPAN
Sbjct: 1081 ASGPHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPAN 1140

Query: 1141 P 1141
            P
Sbjct: 1141 P 1141


>gi|14149793 glutamine rich 2 [Homo sapiens]
          Length = 1663

 Score =  107 bits (267), Expect = 6e-23
 Identities = 69/209 (33%), Positives = 111/209 (53%), Gaps = 13/209 (6%)

Query: 725  SSLGTTVDILQKKIGSLQKSRLK---------EEELERIWGNQIEMMKD---RYITLDKA 772
            S+L    + LQ  + SL  SR           EE L R+    +++  D     IT    
Sbjct: 1225 STLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNL 1284

Query: 773  VENLQIRMDEFKTLQAQIKRLEMNKVNKSTMEEELREKADRSALAGKASRVDLETVALEL 832
            +E+ + +  +   L   +++LE  K N+  +E E+  KAD+SALA K SRV  +    +L
Sbjct: 1285 IEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQL 1344

Query: 833  NEMIQGILFKVTIHEDSWKKAMEELSKDVNTKLVHSDLDPLKKEMEEVWKIVRKLLIEGL 892
            N M+Q ++ K++  E  W+K ++ L  +++ KL   +LDP+K+ +E+ WK +R+ L E  
Sbjct: 1345 NHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRWKSLRQQLRERP 1404

Query: 893  RL-DPDSAAGFRRKLFKRVKCISCDRPVE 920
             L   D AA  RR+L     C+SCDRP+E
Sbjct: 1405 PLYQADEAAAMRRQLLAHFHCLSCDRPLE 1433



 Score = 30.8 bits (68), Expect = 7.7
 Identities = 12/19 (63%), Positives = 18/19 (94%)

Query: 1011 EVDILGVDGILYKGRVNSQ 1029
            EVDILG+DG +YKGR++++
Sbjct: 1592 EVDILGLDGHIYKGRMDTR 1610


>gi|24307909 ral guanine nucleotide dissociation stimulator isoform
           1 [Homo sapiens]
          Length = 914

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 46/129 (35%), Positives = 57/129 (44%), Gaps = 14/129 (10%)

Query: 265 IQVSEPVQ-NPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAP----G 319
           ++ SEP++  P+ L  V     P L P      A++ +RA  P   PA  PE AP    G
Sbjct: 248 LEHSEPIEAEPEALSPV-----PALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPG 302

Query: 320 CTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQ 379
              E AP PAP  +  P   +GLE  P PAL   P P   P    AP   L   PAP   
Sbjct: 303 SELEVAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDP----APSQTLELEPAPAPV 358

Query: 380 PPPLGDWPA 388
           P     WP+
Sbjct: 359 PSLQPSWPS 367



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 47/131 (35%), Positives = 52/131 (39%), Gaps = 8/131 (6%)

Query: 276 LLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPV 335
           LL  + H E  E  PE  S      +    P    ALTP  AP      AP P P   P 
Sbjct: 244 LLAQLEHSEPIEAEPEALSPVP---ALKPTPELELALTPARAPSPVPAPAPEPEPAPTPA 300

Query: 336 PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPL 395
           PG EL +   P P L   P P+V  G   AP P L   PAP   P P       P   P+
Sbjct: 301 PGSELEVAPAPAPELQQAPEPAV--GLESAPAPALELEPAPEQDPAPSQTLELEPAPAPV 358

Query: 396 PQGWPRVGSWP 406
           P   P   SWP
Sbjct: 359 PSLQP---SWP 366


>gi|108796058 ral guanine nucleotide dissociation stimulator isoform
           2 [Homo sapiens]
          Length = 859

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 46/129 (35%), Positives = 57/129 (44%), Gaps = 14/129 (10%)

Query: 265 IQVSEPVQ-NPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAP----G 319
           ++ SEP++  P+ L  V     P L P      A++ +RA  P   PA  PE AP    G
Sbjct: 193 LEHSEPIEAEPEALSPV-----PALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPG 247

Query: 320 CTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQ 379
              E AP PAP  +  P   +GLE  P PAL   P P   P    AP   L   PAP   
Sbjct: 248 SELEVAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDP----APSQTLELEPAPAPV 303

Query: 380 PPPLGDWPA 388
           P     WP+
Sbjct: 304 PSLQPSWPS 312



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 47/131 (35%), Positives = 52/131 (39%), Gaps = 8/131 (6%)

Query: 276 LLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPV 335
           LL  + H E  E  PE  S      +    P    ALTP  AP      AP P P   P 
Sbjct: 189 LLAQLEHSEPIEAEPEALSPVP---ALKPTPELELALTPARAPSPVPAPAPEPEPAPTPA 245

Query: 336 PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPL 395
           PG EL +   P P L   P P+V  G   AP P L   PAP   P P       P   P+
Sbjct: 246 PGSELEVAPAPAPELQQAPEPAV--GLESAPAPALELEPAPEQDPAPSQTLELEPAPAPV 303

Query: 396 PQGWPRVGSWP 406
           P   P   SWP
Sbjct: 304 PSLQP---SWP 311


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 37/100 (37%), Positives = 42/100 (42%), Gaps = 3/100 (3%)

Query: 286 PELLPEGSSAQAVSLSRAQEPAQP---PALTPESAPGCTTEFAPGPAPGTEPVPGLELGL 342
           P L P   S   +  +  Q P+ P   PA TP   P      AP PAP   PV       
Sbjct: 106 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVA 165

Query: 343 ELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382
            L P PA  P P P+  P + PAP P   P PAP   P P
Sbjct: 166 VLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 205



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 14/96 (14%)

Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLEL 344
           VP   P  +      L+ A  PA  P   P +AP      AP PAP   P P        
Sbjct: 128 VPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA------- 180

Query: 345 EPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
            P P   P P P+      PAP P   P PAP A P
Sbjct: 181 -PAPVAAPAPAPA------PAPAPAPAPAPAPDAAP 209



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 44/153 (28%), Positives = 52/153 (33%), Gaps = 35/153 (22%)

Query: 288 LLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPV 347
           LL     A AV++S   EPA       E AP       P PAP + P           PV
Sbjct: 92  LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPS-VPVPAPASTP----------PPV 140

Query: 348 PALGPVPGPSVTPGSLPAPWPVL--------GPVPAPGAQPPPLGDWPALPRRWPLPQGW 399
           P L P P P+  P + P   PV          P PAP   P P+      P   P P   
Sbjct: 141 PVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 200

Query: 400 PRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGS 432
           P                 P P  AP  + E G+
Sbjct: 201 P----------------APAPDAAPQESAEQGA 217



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 27/103 (26%), Positives = 33/103 (32%), Gaps = 8/103 (7%)

Query: 260 EATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPG 319
           E   ++ V  P   P  +  +     P   P  +   A        PA  PA  P  AP 
Sbjct: 123 EQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPA 182

Query: 320 CTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGS 362
                AP PAP   P P         P PA    P  S   G+
Sbjct: 183 PVAAPAPAPAPAPAPAPA--------PAPAPDAAPQESAEQGA 217


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 37/100 (37%), Positives = 42/100 (42%), Gaps = 3/100 (3%)

Query: 286 PELLPEGSSAQAVSLSRAQEPAQP---PALTPESAPGCTTEFAPGPAPGTEPVPGLELGL 342
           P L P   S   +  +  Q P+ P   PA TP   P      AP PAP   PV       
Sbjct: 106 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVA 165

Query: 343 ELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382
            L P PA  P P P+  P + PAP P   P PAP   P P
Sbjct: 166 VLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 205



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 14/96 (14%)

Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLEL 344
           VP   P  +      L+ A  PA  P   P +AP      AP PAP   P P        
Sbjct: 128 VPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA------- 180

Query: 345 EPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
            P P   P P P+      PAP P   P PAP A P
Sbjct: 181 -PAPVAAPAPAPA------PAPAPAPAPAPAPDAAP 209



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 44/153 (28%), Positives = 52/153 (33%), Gaps = 35/153 (22%)

Query: 288 LLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPV 347
           LL     A AV++S   EPA       E AP       P PAP + P           PV
Sbjct: 92  LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPS-VPVPAPASTP----------PPV 140

Query: 348 PALGPVPGPSVTPGSLPAPWPVL--------GPVPAPGAQPPPLGDWPALPRRWPLPQGW 399
           P L P P P+  P + P   PV          P PAP   P P+      P   P P   
Sbjct: 141 PVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 200

Query: 400 PRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGS 432
           P                 P P  AP  + E G+
Sbjct: 201 P----------------APAPDAAPQESAEQGA 217



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 27/103 (26%), Positives = 33/103 (32%), Gaps = 8/103 (7%)

Query: 260 EATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPG 319
           E   ++ V  P   P  +  +     P   P  +   A        PA  PA  P  AP 
Sbjct: 123 EQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPA 182

Query: 320 CTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGS 362
                AP PAP   P P         P PA    P  S   G+
Sbjct: 183 PVAAPAPAPAPAPAPAPA--------PAPAPDAAPQESAEQGA 217


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 37/100 (37%), Positives = 42/100 (42%), Gaps = 3/100 (3%)

Query: 286 PELLPEGSSAQAVSLSRAQEPAQP---PALTPESAPGCTTEFAPGPAPGTEPVPGLELGL 342
           P L P   S   +  +  Q P+ P   PA TP   P      AP PAP   PV       
Sbjct: 117 PPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVA 176

Query: 343 ELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382
            L P PA  P P P+  P + PAP P   P PAP   P P
Sbjct: 177 VLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAP 216



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 14/96 (14%)

Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLEL 344
           VP   P  +      L+ A  PA  P   P +AP      AP PAP   P P        
Sbjct: 139 VPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPA------- 191

Query: 345 EPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
            P P   P P P+      PAP P   P PAP A P
Sbjct: 192 -PAPVAAPAPAPA------PAPAPAPAPAPAPDAAP 220



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 44/153 (28%), Positives = 52/153 (33%), Gaps = 35/153 (22%)

Query: 288 LLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPV 347
           LL     A AV++S   EPA       E AP       P PAP + P           PV
Sbjct: 103 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPS-VPVPAPASTP----------PPV 151

Query: 348 PALGPVPGPSVTPGSLPAPWPVL--------GPVPAPGAQPPPLGDWPALPRRWPLPQGW 399
           P L P P P+  P + P   PV          P PAP   P P+      P   P P   
Sbjct: 152 PVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 211

Query: 400 PRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGS 432
           P                 P P  AP  + E G+
Sbjct: 212 P----------------APAPDAAPQESAEQGA 228



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 27/103 (26%), Positives = 33/103 (32%), Gaps = 8/103 (7%)

Query: 260 EATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPG 319
           E   ++ V  P   P  +  +     P   P  +   A        PA  PA  P  AP 
Sbjct: 134 EQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPA 193

Query: 320 CTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGS 362
                AP PAP   P P         P PA    P  S   G+
Sbjct: 194 PVAAPAPAPAPAPAPAPA--------PAPAPDAAPQESAEQGA 228


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 46/136 (33%), Positives = 52/136 (38%), Gaps = 15/136 (11%)

Query: 292 GSSAQAVSLSRAQEPAQPPALTP-ESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPAL 350
           GS       S    P+ PP   P  S PG    FAP PAP   P P + +     PV   
Sbjct: 283 GSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFG 342

Query: 351 GPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDL 410
            P   P  +P S P       P P P   PPP  D+P LP   P P   P  G+ P    
Sbjct: 343 SPGTPPPPSPPSFPPHPDFAAPPPPP---PPPAADYPTLP---PPPLSQPTGGAPP---- 392

Query: 411 GVLRPTQPQPSRAPPP 426
               P  P P   PPP
Sbjct: 393 ----PPPPPPPPGPPP 404



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 49/171 (28%), Positives = 62/171 (36%), Gaps = 31/171 (18%)

Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCT---TEFAPGPAPGTEPVP-----G 337
           P L+ +  S   V    A     PP     S+P  +       P PA  + PV      G
Sbjct: 226 PTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSG 285

Query: 338 LELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQ 397
           L        V    P P P +  GS P P P   P PAP   PPP+   P  P     P 
Sbjct: 286 LAGPKRSSVVSPSHPPPAPPL--GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP----PV 339

Query: 398 GWPRVGSWPLWDLGVLRPTQPQ----------PSRAPPPATEFGSLWPRPL 438
           G+   G+ P        P+ P           P   PPPA ++ +L P PL
Sbjct: 340 GFGSPGTPP-------PPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPL 383



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 38/153 (24%), Positives = 55/153 (35%), Gaps = 16/153 (10%)

Query: 1000 GDPHVIDYDSAEVDIL-GVDGILYKGRVNSQRGAQPLAVAKELAAVKAPSPPSQSLY--D 1056
            G P  + Y +  +  +  VD   Y     S   + P   +   +    P PP++  Y  D
Sbjct: 223  GYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSP---SPSFSEDNLPPPPAEFSYPVD 279

Query: 1057 RVHSSALFG-----AICPPLCPRSSACSAASGPH---LTMPARPPSLPPLLLLPPLIP-- 1106
                S L G      + P   P +    +  GP       PA PP  PP++ +PP  P  
Sbjct: 280  NQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPV 339

Query: 1107 SLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPA 1139
                P   P  +  S  PH +      PP  PA
Sbjct: 340  GFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA 372



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 30/85 (35%), Positives = 32/85 (37%), Gaps = 11/85 (12%)

Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365
           P  PP  +P S P      AP P P   P P  +    L P P   P  G    P   P 
Sbjct: 344 PGTPPPPSPPSFPPHPDFAAPPPPP---PPPAADYPT-LPPPPLSQPTGGAPPPPPPPPP 399

Query: 366 PWPVLGPVPAPGAQ-----PPPLGD 385
           P P   P P  GA      PPPL D
Sbjct: 400 PGP--PPPPFTGADGQPAIPPPLSD 422


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 53/136 (38%), Positives = 57/136 (41%), Gaps = 22/136 (16%)

Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPV---PGLELGLELEPVPALGPVPGPSVTPGS 362
           P  PP   P   PG  T   PGP PG  P    PG+  GL   P+P L P PGP   PG 
Sbjct: 412 PLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMP-GLR-GPLPRLLP-PGPP--PGR 466

Query: 363 LPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSR 422
            P P P  GP P     PPP G  P LP   P P G P          G++RP    P  
Sbjct: 467 PPGPPP--GPPPGLPPGPPPRGPPPRLPP--PAPPGIPPPRP------GMMRPPLVPPLG 516

Query: 423 APPPATEFGSLWPRPL 438
             PP    G   P PL
Sbjct: 517 PAPP----GLFPPAPL 528



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 41/117 (35%), Positives = 42/117 (35%), Gaps = 18/117 (15%)

Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFA----PGPAPGTEPVPGLELG 341
           P L P G       L     P  PP L P   PG          PGP PG  P P     
Sbjct: 419 PPLRPPGPPT---GLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGP----- 470

Query: 342 LELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQG 398
               P P L P P P   P  LP P P   P P PG   PPL     +P   P P G
Sbjct: 471 -PPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPL-----VPPLGPAPPG 521



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 45/145 (31%), Positives = 54/145 (37%), Gaps = 12/145 (8%)

Query: 301 SRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTP 360
           S A++ +Q        + G +T  +   AP     P       +   P LGP P P + P
Sbjct: 364 SEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP 423

Query: 361 GSLPAPWPVLGPVPAPGAQP---PP-----LGDWPALPRRWPLPQGWPRVGSWPLWDLGV 412
              P P   L P P PGA P   PP      G  P L    P P   P     P   L  
Sbjct: 424 ---PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPP 480

Query: 413 LRPTQPQPSRAPPPATEFGSLWPRP 437
             P +  P R PPPA   G   PRP
Sbjct: 481 GPPPRGPPPRLPPPAPP-GIPPPRP 504



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 35/102 (34%), Positives = 39/102 (38%), Gaps = 15/102 (14%)

Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEP----------V 335
           P L P G       L R   P  PP   P   PG      PGP P   P          +
Sbjct: 440 PFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGI 499

Query: 336 PGLELGLELEP-VPALGPVPGPSVTPGSLPAPWPVLGPVPAP 376
           P    G+   P VP LGP P P + P   PAP P  G + AP
Sbjct: 500 PPPRPGMMRPPLVPPLGPAP-PGLFP---PAPLPNPGVLSAP 537



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 46/180 (25%), Positives = 71/180 (39%), Gaps = 22/180 (12%)

Query: 352 PVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLG 411
           P+P     P ++     ++  +P PGAQPP +     L +          V   PL   G
Sbjct: 140 PLPDMPHAPSNI-----LIQDIPLPGAQPPSI-----LKKTSAYGPPTRAVSILPLLGHG 189

Query: 412 VLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLRE 471
           V R    +    PPP    G   P+ +Q Y  + G AL L     +  + D+     L +
Sbjct: 190 VPRLPPGRKPPGPPP----GPPPPQVVQMYGRKVGFALDLPP---RRRDEDMLYSPELAQ 242

Query: 472 RARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKD 531
           R   D      +  DG P+D    D D  D +  DD   D+   + D  +  H+D+  +D
Sbjct: 243 RGHDDDV-SSTSEDDGYPED---MDQDKHDDS-TDDSDTDKSDGESDGDEFVHRDNGERD 297



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 2/70 (2%)

Query: 1042 AAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLTMPARPPSLPPLLLL 1101
            A+ +  +PP      ++ +  + G   PPL P  +      GP   +P  PP   P  L 
Sbjct: 386  ASSQQQAPPQSVPPSQIQAPPMPGP--PPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLR 443

Query: 1102 PPLIPSLRDP 1111
            PP +P LR P
Sbjct: 444  PPGMPGLRGP 453


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 86/340 (25%), Positives = 119/340 (35%), Gaps = 49/340 (14%)

Query: 248 PEAALAQTTKYLEATRAIQVSEP----------VQNPQLLQTVWHYEVPELLPEGSSAQA 297
           PE   A+  K ++    ++VS            VQ P+   T      P   P G+ A A
Sbjct: 66  PERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATP---PAPPRAPRGAPAAA 122

Query: 298 VSLSRAQEPAQPP------ALTPESAPGCTTEFAPGP-APG-TEPVPGLELGLELEPVPA 349
            + +    PA PP      A  P  AP      A  P +PG  +P P  +        P 
Sbjct: 123 AAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQ-----RAAPL 177

Query: 350 LGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWD 409
             P P P+  P   P   P   P PA  A+ PPL   P  P   P  Q  P         
Sbjct: 178 AAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA--PPQQQQP--------- 226

Query: 410 LGVLRPTQPQPSRAPPPATEFGSLWP---RPLQPYQSRQGEA-LQLAAVQVKGEENDVPS 465
                P QPQP          G+  P   R +  Y    G A  +L   +V+G   +  +
Sbjct: 227 ----PPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAA 282

Query: 466 LRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHK 525
            RG  ER R       R  + G              R  ++ V +    +D D +D   +
Sbjct: 283 ARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEED-DDEDEDEE 341

Query: 526 DDVPKDRGGKDGDPKDRVGKDGAPKEAQPKAPQSALHRLK 565
           DDV +   G +    DR       +    + PQSA  R+K
Sbjct: 342 DDVSE---GSEVPESDRPAGAQHHQLNGERGPQSAKERVK 378



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 26/122 (21%)

Query: 1030 RGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLTMP 1089
            RGA   A A       AP PP           A   A  P   PR++A +AA+ P    P
Sbjct: 116  RGAPAAAAAAAPPPTPAPPPPP----------APVAAAAPARAPRAAA-AAATAPPSPGP 164

Query: 1090 ARP----------PSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPA 1139
            A+P           + PP    PP +     P++AP     +R P +       PP+ PA
Sbjct: 165  AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLP-----PPPQPPA 219

Query: 1140 NP 1141
             P
Sbjct: 220  PP 221


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 58/189 (30%), Positives = 73/189 (38%), Gaps = 37/189 (19%)

Query: 283 YEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAP--------GCTTEFAPGPAPGTEP 334
           + + + LPE S A+  ++S  + P QPP   P S P           +   P   P T P
Sbjct: 5   FSLADALPEHSPAKTSAVSNTK-PGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVP 63

Query: 335 VPGLELGLELEPVPALGPVPGPSVT-PGSLPAPWPVLGPVPAP--------GAQPPPLGD 385
                 G+    VP  GP PGP    P S P+  P  GP PAP        G  P P   
Sbjct: 64  FGPAPTGM-YPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMP 122

Query: 386 WPALPRRWPLPQG---------WPRVGSWPLW--DLGVLRPT------QPQPSRAPPPAT 428
           +P LPR +  P           W  + S P W   +G   PT       P P  APPP  
Sbjct: 123 FPELPRPYGAPTDPAAAGPLGPWGSMSSGP-WAPGMGGQYPTPNMPYPSPGPYPAPPPPQ 181

Query: 429 EFGSLWPRP 437
             G+  P P
Sbjct: 182 APGAAPPVP 190



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 68/245 (27%), Positives = 86/245 (35%), Gaps = 54/245 (22%)

Query: 239 DLWQSVEQLPEAALAQT-----TKYLEATRAIQVSEPVQNPQLLQTVWH----YEVPELL 289
           D +   + LPE + A+T     TK  +  +    S P  NP    +V         P  +
Sbjct: 3   DEFSLADALPEHSPAKTSAVSNTKPGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTV 62

Query: 290 PEGSSAQAV--SLSRAQEPAQPPALTPESAPGCTTEFAPGPAP--------GTEPVPGLE 339
           P G +   +  S+     P  PPA  P S P C     P PAP        G  P P + 
Sbjct: 63  PFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMP 122

Query: 340 L-------GLELEPVPA--LGPVPGPSVTP------GSLPAP---WPVLGPVPAPGAQPP 381
                   G   +P  A  LGP    S  P      G  P P   +P  GP PAP   PP
Sbjct: 123 FPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAP---PP 179

Query: 382 PLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPY 441
           P     A P  W    G    G+W            P P  AP  +     L+P P  P+
Sbjct: 180 PQAPGAAPPVPW----GTVPPGAWG----------PPAPYPAPTGSYPTPGLYPTPSNPF 225

Query: 442 QSRQG 446
           Q   G
Sbjct: 226 QVPSG 230


>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
          Length = 411

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 45/125 (36%), Positives = 55/125 (44%), Gaps = 6/125 (4%)

Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEP--VPGLELGLELEP--VPALGPVPGPSVTPG 361
           P   PA  P    G  +   PGP PG  P  +PG   G    P  VP  GP+PGP   P 
Sbjct: 156 PISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPI 215

Query: 362 SLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPS 421
           S P P P+ GP+P P + P P G  P  P   P P   P     P+   G +    P P+
Sbjct: 216 SGPNPGPIPGPIPGPISGPNP-GPIPG-PISGPNPGLIPGPIPGPISGPGPIIGPIPSPA 273

Query: 422 RAPPP 426
           + P P
Sbjct: 274 QIPGP 278



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 50/145 (34%), Positives = 60/145 (41%), Gaps = 28/145 (19%)

Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPA--LGPVPG--PSVTPG 361
           P   P   P S P       PGP PG  P+PG   G    P+P    GP PG  P   PG
Sbjct: 206 PIPGPISGPISGPN------PGPIPG--PIPGPISGPNPGPIPGPISGPNPGLIPGPIPG 257

Query: 362 SLPAPWPVLGPVPAPGAQPPP---LGDWPAL-PRRWPLPQGWPRV------GSWPLWDLG 411
            +  P P++GP+P+P   P P    G  P L P R   P   P +      GS P    G
Sbjct: 258 PISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLPGLAPILGPGSGP--GSG 315

Query: 412 VLRPTQPQPSRAPPPATEFGSLWPR 436
            +    P P   P PA     LWP+
Sbjct: 316 SVPAPIPGPGSLPAPA----PLWPQ 336



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 43/129 (33%), Positives = 52/129 (40%), Gaps = 16/129 (12%)

Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365
           PAQ P   P S PG     A  P+P   P+PG   G    P P  GP+PGP   P  +P 
Sbjct: 106 PAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPG 165

Query: 366 P------WPVLGPVPA--PGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQ 417
           P       P  GP+P   PG  P P+      P   P+P   P   S P+        + 
Sbjct: 166 PISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPI--------SG 217

Query: 418 PQPSRAPPP 426
           P P   P P
Sbjct: 218 PNPGPIPGP 226



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 43/126 (34%), Positives = 53/126 (42%), Gaps = 8/126 (6%)

Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLEL 344
           +P  +P      A   S    P   P   P   PG      PGP  G  P+PG   G   
Sbjct: 113 LPGSIPGPIPGPAQIPSPIPAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFS 172

Query: 345 EPVPALGPVPGPSVTPGSLPAP--WPVLGP--VPAPGAQPPPLGDWPALPRRWPLPQGWP 400
            P P  GP+PGP+  PG +P P   P+ GP  VP PG  P P+    + P   P+P   P
Sbjct: 173 GPNP--GPIPGPN--PGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIP 228

Query: 401 RVGSWP 406
              S P
Sbjct: 229 GPISGP 234



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 39/134 (29%), Positives = 52/134 (38%), Gaps = 15/134 (11%)

Query: 294 SAQAVSLSRAQEPAQPPA-LTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGP 352
           +A  V  + A  P + P+ + P + P   +       PG     G+   L   P P   P
Sbjct: 43  AAPLVPAASASAPQRGPSGILPAAEPTICSLHQAWGGPGCRAQKGIPAALSPGPGPIPAP 102

Query: 353 VPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGV 412
           +PGP+  PG LP   P  GP+P P   P P+          P P   P  G  P+   G 
Sbjct: 103 IPGPAQIPGPLPGSIP--GPIPGPAQIPSPI----------PAPIPGPISG--PVQIPGP 148

Query: 413 LRPTQPQPSRAPPP 426
            R   P P   P P
Sbjct: 149 FRGPIPGPISGPAP 162



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 39/120 (32%), Positives = 49/120 (40%), Gaps = 22/120 (18%)

Query: 309 PPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPAL--GPVPGPSVTPGSLPA- 365
           P AL+P   P       P P PG   +PG        P+P    GP+PGP+  P  +PA 
Sbjct: 89  PAALSPGPGP------IPAPIPGPAQIPG--------PLPGSIPGPIPGPAQIPSPIPAP 134

Query: 366 -PWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAP 424
            P P+ GPV  PG    P+    + P   P P   P  G  P    G +    P P   P
Sbjct: 135 IPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNP----GPIPGPNPGPIPGP 190



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 33/107 (30%), Positives = 41/107 (38%), Gaps = 30/107 (28%)

Query: 310 PALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSV----------- 358
           P   P    G      PGP PG    PG  +G    P+P+   +PGP             
Sbjct: 236 PGPIPGPISGPNPGLIPGPIPGPISGPGPIIG----PIPSPAQIPGPGRLQGPGPILSPG 291

Query: 359 ---TPGSLPAPWPVLGP------------VPAPGAQPPPLGDWPALP 390
              +PGSLP   P+LGP            +P PG+ P P   WP  P
Sbjct: 292 RMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPLWPQSP 338



 Score = 30.8 bits (68), Expect = 7.7
 Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 26/72 (36%)

Query: 298 VSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPS 357
           +S  R + P   P L P   PG       GP  G+ P                 P+PG  
Sbjct: 288 LSPGRMRSPGSLPGLAPILGPG------SGPGSGSVP----------------APIPG-- 323

Query: 358 VTPGSLPAPWPV 369
             PGSLPAP P+
Sbjct: 324 --PGSLPAPAPL 333


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 54/184 (29%), Positives = 65/184 (35%), Gaps = 19/184 (10%)

Query: 306 PAQPPA------LTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVT 359
           PA PPA       +PE  P    E APGP P        EL  E  P PA  P   P+  
Sbjct: 37  PAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPE 96

Query: 360 PGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQ 419
           P + PAP P   P P P   P P  +    P   P  +  P     P  +L      +  
Sbjct: 97  PATEPAPEPATEPAPEPA--PEPATESAPEPTPEPALESVPE----PAPELTPEVAPELA 150

Query: 420 PSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLRERARKDGAP 479
           P   P P TE    +     P + R   A  L    V   E      RGL+       +P
Sbjct: 151 PEPTPEPVTELAPEFCPEAAP-EFRPSPAPCLLQCPVDTRE------RGLKTSPSPSPSP 203

Query: 480 KDRT 483
             RT
Sbjct: 204 SPRT 207



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 63/187 (33%), Positives = 70/187 (37%), Gaps = 32/187 (17%)

Query: 270 PVQNPQLLQTVWHYEVPELLPE---GSSAQAVSLSR-----------AQEPAQPPALTP- 314
           P   P LL       +PE  PE   G   +A S S            A EPA  PA  P 
Sbjct: 39  PPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPA 98

Query: 315 -ESAPGCTTEFAPGPAP--GTEPVPGLELGLELEPVPALG--PVPGPSVTPGSLPAPWPV 369
            E AP   TE AP PAP   TE  P      E  P PAL   P P P +TP   P   P 
Sbjct: 99  TEPAPEPATEPAPEPAPEPATESAP------EPTPEPALESVPEPAPELTPEVAPELAP- 151

Query: 370 LGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATE 429
             P P P  +  P     A P   P P   P +   P+        T P PS +P P T 
Sbjct: 152 -EPTPEPVTELAPEFCPEAAPEFRPSPA--PCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208

Query: 430 FGSLWPR 436
               W R
Sbjct: 209 MS--WSR 213



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 41/139 (29%), Positives = 47/139 (33%), Gaps = 4/139 (2%)

Query: 248 PEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPA 307
           PEA     T+          +EP   P           P   P    A   +   A EP 
Sbjct: 67  PEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPT 126

Query: 308 QPPAL--TPESAPGCTTEFAPGPAPGTEPVPGLELGLEL--EPVPALGPVPGPSVTPGSL 363
             PAL   PE AP  T E AP  AP   P P  EL  E   E  P   P P P +    +
Sbjct: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPV 186

Query: 364 PAPWPVLGPVPAPGAQPPP 382
                 L   P+P   P P
Sbjct: 187 DTRERGLKTSPSPSPSPSP 205



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 42/138 (30%), Positives = 52/138 (37%), Gaps = 25/138 (18%)

Query: 348 PALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWP- 406
           P  G  P  S  P   P PWP   P PAP   PP L +  A P   P+P+  P +   P 
Sbjct: 14  PQDGEQPAESPEP---PPPWPPPPPPPAPPPAPPLLSE--ASPE--PIPEPCPELAPGPC 66

Query: 407 ----------LWDLGVLRP-TQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQ 455
                     L+      P T+P    AP PATE     P P +P      E     A +
Sbjct: 67  PEATSESATELYTEPTPEPATEPASEPAPEPATE-----PAP-EPATEPAPEPAPEPATE 120

Query: 456 VKGEENDVPSLRGLRERA 473
              E    P+L  + E A
Sbjct: 121 SAPEPTPEPALESVPEPA 138



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 31/113 (27%), Positives = 36/113 (31%), Gaps = 12/113 (10%)

Query: 329 APGTEPVPGLELGLELEPVPALGPVPGPSVT------------PGSLPAPWPVLGPVPAP 376
           A GT P    E   E    P   P P P               P  +P P P L P P P
Sbjct: 8   AQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCP 67

Query: 377 GAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATE 429
            A      +    P   P  +        P  +      T+P P  AP PATE
Sbjct: 68  EATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATE 120


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 51/178 (28%), Positives = 63/178 (35%), Gaps = 24/178 (13%)

Query: 265 IQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEF 324
           + V  PV +  L+      +V   +P  S   A   + A  P   P L  +S P   +  
Sbjct: 225 LSVPAPVPHSGLVPV----QVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSAS 280

Query: 325 APGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLP------------APWPVLGP 372
              P P + P  G        PVP   P P P   P S P            AP  VL P
Sbjct: 281 VLVPVPASAPPSG--------PVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAP 332

Query: 373 VPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEF 430
           VP P   P P    PA P    +P   P   S P     ++    P P  AP PA  F
Sbjct: 333 VPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIF 390



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 45/151 (29%), Positives = 56/151 (37%), Gaps = 13/151 (8%)

Query: 235 SSPLDLWQSV-EQLPEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGS 293
           S+PL +  SV   +P +A       L A     +S PV  P L             P   
Sbjct: 272 SNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQ--------APVPP 323

Query: 294 SAQAVSLSRAQEP--AQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALG 351
           SA  + L+    P  A  PA TP +AP   +   P P P + P     L     P P   
Sbjct: 324 SAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPA 383

Query: 352 PVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382
           P P P  TP   P P P   P   P + P P
Sbjct: 384 PTPAPIFTPA--PTPMPAATPAAIPTSAPIP 412



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 31/76 (40%), Positives = 36/76 (47%), Gaps = 14/76 (18%)

Query: 318 PGCTTEFAPGPAPGTEPVPG-----------LELGLEL-EPVPALGPVPGPSVTPGSLPA 365
           P  TT F+P PAP   P PG            ++ L +  PVP  G VP    T  S+PA
Sbjct: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVAT--SVPA 247

Query: 366 PWPVLGPVPAPGAQPP 381
           P P L PVPA    PP
Sbjct: 248 PSPPLAPVPALAPAPP 263



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 52/168 (30%), Positives = 60/168 (35%), Gaps = 40/168 (23%)

Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELE 345
           P   P      A  L+  Q P  P A T   AP  T   AP PA  T P           
Sbjct: 300 PAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPA-STPPA---------- 348

Query: 346 PVPALGPVPGPSVTPGSLP----------APWPVLGPVPA----PGAQPPPLGDWPALPR 391
             PA   VP P+ TP S P          AP PV  P PA    P   P P     A+P 
Sbjct: 349 -APAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPT 407

Query: 392 RWPLPQGW------------PRVGSWPL-WDLG-VLRPTQPQPSRAPP 425
             P+P  +            P +   PL +  G VL P+QP     PP
Sbjct: 408 SAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 40/125 (32%), Positives = 46/125 (36%), Gaps = 30/125 (24%)

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLP----APWPVLGPVPAPGAQP--- 380
           P  GT P+  +       P P   P PG +  P S+P     P  V  PVP  G  P   
Sbjct: 184 PVEGTLPL--VTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQV 241

Query: 381 --------PPLGDWPALPRRWPLPQGWPRV--GSWPL-WDLGVL-------RPTQPQPSR 422
                   PPL   PAL    P P   P +   S PL     VL        P+ P P  
Sbjct: 242 ATSVPAPSPPLAPVPALA---PAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLS 298

Query: 423 APPPA 427
           AP PA
Sbjct: 299 APAPA 303


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo
            sapiens]
          Length = 1125

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 82/339 (24%), Positives = 122/339 (35%), Gaps = 60/339 (17%)

Query: 286  PELLPEGSSAQAVSLSRAQEPAQPPALTPESAP----GCTTEFAPGPAPGTEPVPGLELG 341
            P  LP     Q VSL   Q  A  P +  ++      G      P   P   P P L+  
Sbjct: 792  PTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRF 851

Query: 342  LELEPVPA------LGPVPGPS----VTPGSLPAPWPVLGPVPAPGAQP----------- 380
              + P P        GP PGP       P  +  P+P  GP   PG  P           
Sbjct: 852  PLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGG 911

Query: 381  PPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQP 440
            P   D    P + P  Q  P+    P       +  QP PS+ PPP  +         QP
Sbjct: 912  PEDRDGRQQPPQQPQQQPQPQAPQQPQQQ----QQQQPPPSQQPPPTQQ---------QP 958

Query: 441  YQSRQGEALQLAAVQVK---GEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDV 497
             Q R     Q  + + +   G  +    +   RER       +D + +D   +   G+  
Sbjct: 959  QQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRD---RREWGRRS 1015

Query: 498  DPKDRAHKDDVPKDRGG-----KDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEA 552
              +DR H+D   ++R       ++ D +DR  + +  + RG +  +  DR G +   K  
Sbjct: 1016 PDRDR-HRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGN---KTV 1071

Query: 553  QPKAPQ-------SALHRLKTTAAIAAAAAAAYAAATSS 584
            +P   Q       S L +  + AA+   +    A ATSS
Sbjct: 1072 EPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSS 1110



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 67/248 (27%), Positives = 86/248 (34%), Gaps = 52/248 (20%)

Query: 241 WQSVEQLPEAALAQT----TKYLEATRAIQVSEPVQNPQL-LQTVWHYEVPELLPEGSSA 295
           W+ + + PE  +AQ     T + E    I    PV  P + +        P++ P     
Sbjct: 630 WKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGP 689

Query: 296 QAVSLSRAQEPAQPPALTPESA---PGCTTEFAPGPAPGTEPVPGLELGLELEPVPA--L 350
             V         QPPA TP      PG    F PG  P   P P L  G     +P   L
Sbjct: 690 PVVGA------LQPPAFTPPLGIPPPG----FGPGVPPPPPPPPFLRPGFNPMHLPPGFL 739

Query: 351 GPVPGPSVTPG-SLPAPW--PVLGPVPAPGAQP-PPLGDW---------PALPRRWPLPQ 397
            P P P +TP  S+P P   P+  P    GA+     GD          PA P   P P 
Sbjct: 740 PPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPP 799

Query: 398 --------GWPRVGSWPLWDLGV-----------LRPTQPQPSRAPPPATEFGSLWPRPL 438
                   G   V   P+  L             L P Q  P   PP    F  + PRP+
Sbjct: 800 VTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPM 859

Query: 439 QPYQSRQG 446
            P+   +G
Sbjct: 860 PPHMMHRG 867



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 27/115 (23%), Positives = 40/115 (34%), Gaps = 17/115 (14%)

Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLE----- 339
           V E   E ++A   +   A  P  P A  P +A        P  AP   P  G++     
Sbjct: 274 VEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYT 333

Query: 340 ------------LGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382
                       +G++ +P+    P+P     PG    P P   P+  P   P P
Sbjct: 334 QHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP 388


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo
            sapiens]
          Length = 1132

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 82/339 (24%), Positives = 122/339 (35%), Gaps = 60/339 (17%)

Query: 286  PELLPEGSSAQAVSLSRAQEPAQPPALTPESAP----GCTTEFAPGPAPGTEPVPGLELG 341
            P  LP     Q VSL   Q  A  P +  ++      G      P   P   P P L+  
Sbjct: 799  PTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRF 858

Query: 342  LELEPVPA------LGPVPGPS----VTPGSLPAPWPVLGPVPAPGAQP----------- 380
              + P P        GP PGP       P  +  P+P  GP   PG  P           
Sbjct: 859  PLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGG 918

Query: 381  PPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQP 440
            P   D    P + P  Q  P+    P       +  QP PS+ PPP  +         QP
Sbjct: 919  PEDRDGRQQPPQQPQQQPQPQAPQQPQQQ----QQQQPPPSQQPPPTQQ---------QP 965

Query: 441  YQSRQGEALQLAAVQVK---GEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDV 497
             Q R     Q  + + +   G  +    +   RER       +D + +D   +   G+  
Sbjct: 966  QQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRD---RREWGRRS 1022

Query: 498  DPKDRAHKDDVPKDRGG-----KDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEA 552
              +DR H+D   ++R       ++ D +DR  + +  + RG +  +  DR G +   K  
Sbjct: 1023 PDRDR-HRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGN---KTV 1078

Query: 553  QPKAPQ-------SALHRLKTTAAIAAAAAAAYAAATSS 584
            +P   Q       S L +  + AA+   +    A ATSS
Sbjct: 1079 EPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSS 1117



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 66/271 (24%), Positives = 85/271 (31%), Gaps = 76/271 (28%)

Query: 241 WQSVEQLPEAALAQT----TKYLEATRAIQVSEPVQNPQL-LQTVWHYEVPELLPEGSSA 295
           W+ + + PE  +AQ     T + E    I    PV  P + +        P++ P     
Sbjct: 615 WKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGP 674

Query: 296 QAVSLSRAQEPAQPPALTPESA---PGCTTEFAPGPAPGTEPVPGLELGLELEPVPA--L 350
             V         QPPA TP      PG    F PG  P   P P L  G     +P   L
Sbjct: 675 PVVGA------LQPPAFTPPLGIPPPG----FGPGVPPPPPPPPFLRPGFNPMHLPPGFL 724

Query: 351 GPVPGPSVTPGSLPAPWPVLGPVPAPGA----------------QPPPL----------- 383
            P P P +TP  +  P P   P+  P +                 P P            
Sbjct: 725 PPGPPPPITP-PVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAES 783

Query: 384 GDW---------PALPRRWPLPQ--------GWPRVGSWPLWDLGV-----------LRP 415
           GD          PA P   P P         G   V   P+  L             L P
Sbjct: 784 GDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIP 843

Query: 416 TQPQPSRAPPPATEFGSLWPRPLQPYQSRQG 446
            Q  P   PP    F  + PRP+ P+   +G
Sbjct: 844 LQRPPGMPPPHLQRFPLMPPRPMPPHMMHRG 874



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 27/115 (23%), Positives = 40/115 (34%), Gaps = 17/115 (14%)

Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLE----- 339
           V E   E ++A   +   A  P  P A  P +A        P  AP   P  G++     
Sbjct: 259 VEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYT 318

Query: 340 ------------LGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382
                       +G++ +P+    P+P     PG    P P   P+  P   P P
Sbjct: 319 QHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP 373


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo
            sapiens]
          Length = 1147

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 82/339 (24%), Positives = 122/339 (35%), Gaps = 60/339 (17%)

Query: 286  PELLPEGSSAQAVSLSRAQEPAQPPALTPESAP----GCTTEFAPGPAPGTEPVPGLELG 341
            P  LP     Q VSL   Q  A  P +  ++      G      P   P   P P L+  
Sbjct: 814  PTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRF 873

Query: 342  LELEPVPA------LGPVPGPS----VTPGSLPAPWPVLGPVPAPGAQP----------- 380
              + P P        GP PGP       P  +  P+P  GP   PG  P           
Sbjct: 874  PLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGG 933

Query: 381  PPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQP 440
            P   D    P + P  Q  P+    P       +  QP PS+ PPP  +         QP
Sbjct: 934  PEDRDGRQQPPQQPQQQPQPQAPQQPQQQ----QQQQPPPSQQPPPTQQ---------QP 980

Query: 441  YQSRQGEALQLAAVQVK---GEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDV 497
             Q R     Q  + + +   G  +    +   RER       +D + +D   +   G+  
Sbjct: 981  QQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRD---RREWGRRS 1037

Query: 498  DPKDRAHKDDVPKDRGG-----KDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEA 552
              +DR H+D   ++R       ++ D +DR  + +  + RG +  +  DR G +   K  
Sbjct: 1038 PDRDR-HRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGN---KTV 1093

Query: 553  QPKAPQ-------SALHRLKTTAAIAAAAAAAYAAATSS 584
            +P   Q       S L +  + AA+   +    A ATSS
Sbjct: 1094 EPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSS 1132



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 66/271 (24%), Positives = 85/271 (31%), Gaps = 76/271 (28%)

Query: 241 WQSVEQLPEAALAQT----TKYLEATRAIQVSEPVQNPQL-LQTVWHYEVPELLPEGSSA 295
           W+ + + PE  +AQ     T + E    I    PV  P + +        P++ P     
Sbjct: 630 WKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGP 689

Query: 296 QAVSLSRAQEPAQPPALTPESA---PGCTTEFAPGPAPGTEPVPGLELGLELEPVPA--L 350
             V         QPPA TP      PG    F PG  P   P P L  G     +P   L
Sbjct: 690 PVVGA------LQPPAFTPPLGIPPPG----FGPGVPPPPPPPPFLRPGFNPMHLPPGFL 739

Query: 351 GPVPGPSVTPGSLPAPWPVLGPVPAPGA----------------QPPPL----------- 383
            P P P +TP  +  P P   P+  P +                 P P            
Sbjct: 740 PPGPPPPITP-PVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAES 798

Query: 384 GDW---------PALPRRWPLPQ--------GWPRVGSWPLWDLGV-----------LRP 415
           GD          PA P   P P         G   V   P+  L             L P
Sbjct: 799 GDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIP 858

Query: 416 TQPQPSRAPPPATEFGSLWPRPLQPYQSRQG 446
            Q  P   PP    F  + PRP+ P+   +G
Sbjct: 859 LQRPPGMPPPHLQRFPLMPPRPMPPHMMHRG 889



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 27/115 (23%), Positives = 40/115 (34%), Gaps = 17/115 (14%)

Query: 285 VPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLE----- 339
           V E   E ++A   +   A  P  P A  P +A        P  AP   P  G++     
Sbjct: 274 VEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYT 333

Query: 340 ------------LGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382
                       +G++ +P+    P+P     PG    P P   P+  P   P P
Sbjct: 334 QHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP 388


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 53/160 (33%), Positives = 63/160 (39%), Gaps = 20/160 (12%)

Query: 286  PELLPEGSSAQAVSLSRAQEPA--QPPALTPESAPGCTTEFAP---GPAPGTEPVPGLEL 340
            P+  P+   +QA      Q+P   Q P L P  APG     +P    P PG    P   L
Sbjct: 955  PQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPL 1014

Query: 341  GLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWP 400
              +L P PA  P+P  S   G+LP P P  GP   P    PPL   PA   R   PQ  P
Sbjct: 1015 HTQLYPGPAQDPLPAHS---GALPFPSP--GP---PQPPHPPLAYGPAPSTRPMGPQAAP 1066

Query: 401  RVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQP 440
                 P         + P P   P PA   G   P P+ P
Sbjct: 1067 LTIRGP----SSAGQSTPSPHLVPSPAPSPG---PGPVPP 1099



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 44/158 (27%), Positives = 57/158 (36%), Gaps = 20/158 (12%)

Query: 290  PEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPA 349
            P  ++  ++        A  P  TP   P C     P P P   P P         P  A
Sbjct: 879  PATTTVDSIQAPIPSHTAPRPNPTPAPPPPCF----PVPPPQPLPTP------YTYPAGA 928

Query: 350  LGPVPGPSVTPGSLPA--PWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPL 407
              P+P        +PA  P P +GP P P  QP P   +   P + PLP   P +  +P 
Sbjct: 929  KQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHL--FPP 986

Query: 408  WDLGVLRPTQPQPSR------APPPATEFGSLWPRPLQ 439
               G+L P  P P          PP      L+P P Q
Sbjct: 987  QAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQ 1024



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 14/139 (10%)

Query: 306 PAQPPALTPESAPGCTT--EFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSL 363
           PA P A  P + P   +  E A    P T  V  ++  +     P   P P P       
Sbjct: 853 PAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPP------ 906

Query: 364 PAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRA 423
           P  +PV  P P P     P G    +P +     G P    +P   +G     QPQP   
Sbjct: 907 PPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIP--AGFPAPRIG----PQPQPHPQ 960

Query: 424 PPPATEFGSLWPRPLQPYQ 442
           P P+  FG   P+   P Q
Sbjct: 961 PHPSQAFGPQPPQQPLPLQ 979



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 28/102 (27%)

Query: 289  LPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVP 348
            LP  S A         +P  PP              A GPAP T P     +G +  P+ 
Sbjct: 1027 LPAHSGALPFPSPGPPQPPHPP-------------LAYGPAPSTRP-----MGPQAAPLT 1068

Query: 349  ALGP------VPGPSVTPGSLPAPWPVLGPVPA--PGAQPPP 382
              GP       P P + P   P+P P  GPVP   P A+PPP
Sbjct: 1069 IRGPSSAGQSTPSPHLVPSPAPSPGP--GPVPPRPPAAEPPP 1108



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 1/51 (1%)

Query: 306  PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGP 356
            PA+PP L P S P  T   +  P P + P+P      E  PVP   P  GP
Sbjct: 1523 PAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPE-APSSGP 1572



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 25/89 (28%)

Query: 341  GLELEPVPAL-GPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGW 399
            GLE  PV +L GP   P + P SLP   P+      P + PPPL          PLP+  
Sbjct: 1512 GLE-SPVASLPGPAEPPGLPPASLPESTPI------PSSSPPPLSS--------PLPEA- 1555

Query: 400  PRVGSWPLWDLGVLRPTQPQPSRAPPPAT 428
            P+    P        P    PS  PP ++
Sbjct: 1556 PQPKEEP--------PVPEAPSSGPPSSS 1576


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 89/334 (26%), Positives = 110/334 (32%), Gaps = 44/334 (13%)

Query: 286  PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTT---EFAPGPAPGTEPVPGLELGL 342
            P   P        + S    P  P A  P    G  T   + AP P   T P P    G 
Sbjct: 943  PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP---KGG 999

Query: 343  ELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPA---LPRRWPLPQGW 399
               P P   P P P+VTP S P   P   P P  GA  PP    P+    P   PLP+G 
Sbjct: 1000 PATPSPKGAPTP-PAVTPPS-PKGSPAATPFP-KGASTPPAATPPSPKGSPAATPLPKGA 1056

Query: 400  PR--VGSWPLWDLGVLRPT---QPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAV 454
            P     + P    G   P+    P P  A PP+ + G   P P       +G  +  AA 
Sbjct: 1057 PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP-------KGAPMPPAAT 1109

Query: 455  QVKGEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDV---PKD 511
                     PS +G        GAP   T     P  +GG    P   A        P  
Sbjct: 1110 P--------PSPKGGLATPPHKGAP--TTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159

Query: 512  RGGKDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEAQPKAPQSALHRLKTTAAIA 571
            +GG    P   A     P         PK  +    +PK A P  P +     K   A  
Sbjct: 1160 KGGLATPPPKGA-----PTTPAATPPSPKGGLATP-SPKGA-PTTPAATPPSPKGGLATP 1212

Query: 572  AAAAAAYAAATSSAAQAAKVAAKFVKDAPATKMA 605
            +   A    A +  +    +A    K AP T  A
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 91/342 (26%), Positives = 113/342 (33%), Gaps = 54/342 (15%)

Query: 309  PPALTPESAPGCTT----EFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTP---- 360
            PPA TP S  G       + AP PA  T P P    G      P   P P P+ TP    
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPK---GGPATSPPKGAPTP-PAATPPSPK 1321

Query: 361  GSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRP----- 415
            GS   P P   P P P   PP     P LP   P  +G P   + P    G   P     
Sbjct: 1322 GSPGTPPPKGAPTP-PAVTPPSPKGTPTLPATTPSSKGGP---TTPSSKEGPTPPAATPS 1377

Query: 416  -------TQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQL----AAVQVKGEENDVP 464
                   T P P R P   +  G      + P   ++  A  +    AA   KG+     
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437

Query: 465  SLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAH 524
                  ++A    APK        P  +G    DP   A     PK+       PK  A 
Sbjct: 1438 VTPVSLKKAPATSAPKG---GPATPSSKG----DPTLPAVTPPSPKEPPA----PKQVAT 1486

Query: 525  KDDVPKDRG--GKDGDPKDRVGKDGAPKEA--------QPKAPQSALHRLKTTAAIAAAA 574
                 K        G P        +PKE          P AP + L   KT A +A   
Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546

Query: 575  AAAYAAATSSAAQAAKVAAKFVKDAPATKMAAIATDTAAAGP 616
            A    A T  + +    A    K+APAT  +  A+   A  P
Sbjct: 1547 ALIPPAMTVPSPKKTP-AIPTPKEAPATPSSKEASSPPAVTP 1587



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 76/343 (22%), Positives = 100/343 (29%), Gaps = 49/343 (14%)

Query: 286  PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELE 345
            P   P        + S    P  P A  P    G  T    G        P    G    
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257

Query: 346  PVPALGPVPGPSVTP----GSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPR 401
            P P   P P P+ TP    G L  P     P PA    P P G     P     P+G P 
Sbjct: 1258 PPPKGAPTP-PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP-----PKGAPT 1311

Query: 402  VGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEEN 461
              +           T P P  +P      G+  P  + P   +    L       KG   
Sbjct: 1312 PPA----------ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG--- 1358

Query: 462  DVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKD 521
                  G    + K+G     T     P  +GG  + P        +P  +G    DP  
Sbjct: 1359 ------GPTTPSSKEGP----TPPAATPSHKGGPAMTPPSPKRGPAIPSPKG----DPTS 1404

Query: 522  RAHKDDVPKDRGGKDGDPKDRVGKDGA--PKEAQPKAPQSALHRLKTTAAIAAAAAAAYA 579
             A     PK        P   V ++GA  P +     P      LK   A +A       
Sbjct: 1405 PAVIPLSPKKA------PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458

Query: 580  AATSSAAQAAKVAAKFVKDAPATKMAAIATD----TAAAGPLG 618
             ++        V     K+ PA K  A ++      A   P+G
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 80/312 (25%), Positives = 96/312 (30%), Gaps = 48/312 (15%)

Query: 290  PEGSSA-----QAVSLSRAQEPAQP---PALTPESAPGCTTEFAPGPAPGTEPVPGLELG 341
            P+GS A     +  S   A  P  P   PA TP      TT  A  P+P   P      G
Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078

Query: 342  LELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAP--GAQPPPLGDWPALPR-------- 391
                P        G   TP    AP P     P+P  G   PP    P  P         
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138

Query: 392  --RWPLPQGWPRV-GSWPLWDLGVLRPTQPQPSRAP------PPATEFGSLWP----RPL 438
                P P+G P    + P    G L    P P  AP      PP+ + G   P     P 
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGL--ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196

Query: 439  QPYQSRQGEALQLAAVQVKGEEN----DVPSLRGLRERARKDGAPKDRTRKDGVPKDRGG 494
             P  +       LA    KG         PS +G        GAP   T     P  +GG
Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP--TTPAATPPSPKGG 1254

Query: 495  KDVDPKDRAHKDDV---PKDRGGKDVDPKDRAHKDDV---PKDRGGKDGDPKDRVGKDGA 548
                P   A        P  +GG    P   A    V   P  +GG    P         
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA---PT 1311

Query: 549  PKEAQPKAPQSA 560
            P  A P +P+ +
Sbjct: 1312 PPAATPPSPKGS 1323



 Score = 37.4 bits (85), Expect = 0.082
 Identities = 85/355 (23%), Positives = 110/355 (30%), Gaps = 49/355 (13%)

Query: 291  EGSSAQAVSLSRAQEPAQPPALTPESAPGCT-TEFAPGPAPGTEPVPGLELGLELEPVPA 349
            E  +   V+L   +E    PA  P+ AP  + T  +P  A  T P P    G+   P P 
Sbjct: 884  ETPTPSVVNLPFPKEGPATPA--PKQAPALSMTSSSPKKARAT-PAPK---GIPASPSPK 937

Query: 350  LGPVP---------GPSVTPGSLPAPWPVL--------GP-VPAPGAQPPPLGDWPALPR 391
              P P         G   TP    AP P          GP  P+P   P P    P  P+
Sbjct: 938  GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997

Query: 392  ---RWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEA 448
                 P P+G P   +        + P  P+ S A  P  +  S  P    P       A
Sbjct: 998  GGPATPSPKGAPTPPA--------VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049

Query: 449  LQLAAVQVKGEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDV 508
              L           +PS +G        GAP         PK  G     PK        
Sbjct: 1050 TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG-GPATPSPKGAPMPPAA 1108

Query: 509  --PKDRGGKDVDPKDRAHKDDV---PKDRGGKDGDPKDRVGKDGAP--KEAQPKAPQSAL 561
              P  +GG    P   A        P  +GG    P       GAP    A P +P+  L
Sbjct: 1109 TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP-----PKGAPTTPAATPPSPKGGL 1163

Query: 562  HRLKTTAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAPATKMAAIATDTAAAGP 616
                   A    AA   +     A  + K A       P +    +AT +    P
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1218



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 41/160 (25%), Positives = 54/160 (33%), Gaps = 25/160 (15%)

Query: 291 EGSSAQAVSLSRAQEPAQP--PALTPESAPG--------CTTEFAPGPAPGTEPVPGLEL 340
           +GS+     +     P  P   +  PE++           TT     P+P   P P    
Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871

Query: 341 GLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPL---GDWPALPRRWPLPQ 397
            L  + V  L P   P  TP  +  P+P  GP      Q P L      P   R  P P+
Sbjct: 872 PLSPKGV-TLPPKETP--TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK 928

Query: 398 GWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRP 437
           G P   S             P P  A PP+ + G   P P
Sbjct: 929 GIPASPS---------PKGAPTPPAATPPSPKGGPATPSP 959



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 1029 QRGAQPLAVAKELA-AVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLT 1087
            Q+ +   A  K+ + + K P  P +S      ++A F  + P   P S++ SAA  P ++
Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK--PESASVSAAPSPPVS 1799

Query: 1088 MPARP---PSLPPLLLLPPLIPSL 1108
            +P  P   P+LPP     P  P L
Sbjct: 1800 LPLAPSPVPTLPPKQQFLPSSPGL 1823



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 20/91 (21%)

Query: 296  QAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPG 355
            +A +   ++E + PPA+TP +  G     AP P          EL   L P     P P 
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKG-----APSPK---------EL---LIPPAVTSPSPK 1611

Query: 356  PSVTPGSLPAPWPVLGP-VPAPGAQP--PPL 383
             + TP ++  P P  GP  PAP   P  PP+
Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTSPPV 1642



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 18/69 (26%), Positives = 30/69 (43%)

Query: 1073 PRSSACSAASGPHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGR 1132
            P+    + +S    T+PA  P  P     P  + +   P++AP +     AP + + +  
Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511

Query: 1133 KPPEEPANP 1141
             P E PA P
Sbjct: 1512 SPKEVPATP 1520


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 50/196 (25%), Positives = 71/196 (36%), Gaps = 14/196 (7%)

Query: 244 VEQLPEAALAQTTKYLEATRA--IQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLS 301
           +E  P      TT  L A+       S    +P L     H  +        ++      
Sbjct: 302 IEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADSP 361

Query: 302 RAQEPAQPPALTPESAPGCTTEFAPGPA-PGTEPVPGLELGLE---LEPVPA--LGPVPG 355
           R Q  +  PA+   SAP   T ++ GPA P  +P       +     +PVPA    P PG
Sbjct: 362 RPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPG 421

Query: 356 PSVTPGSL-PAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLR 414
            + +P    P+P P   P PAP   P P+  +   P     P   P     P     V  
Sbjct: 422 ANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAP----SVAY 477

Query: 415 PTQP-QPSRAPPPATE 429
              P +P+  PP  T+
Sbjct: 478 SGGPAEPASRPPWVTD 493



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 36/116 (31%), Positives = 41/116 (35%), Gaps = 21/116 (18%)

Query: 282 HYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLEL- 340
           +Y      P  + A   S + A  P+  P  TP  AP  T    P PAP   P P +   
Sbjct: 423 NYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYT----PSPAPNYNPAPSVAYS 478

Query: 341 GLELEPVPALGPV----------PGPSVTPGS---LPAPWPVLGPVPAPGAQPPPL 383
           G   EP      V          PG S T  S   LP   P   P    G Q PPL
Sbjct: 479 GGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPA---GPQVPPL 531


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 60/223 (26%), Positives = 75/223 (33%), Gaps = 16/223 (7%)

Query: 248 PEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPA 307
           P+A  A     L+A  +   S PVQ P        +  P   P   SA   S +     A
Sbjct: 650 PQAPNALAVHLLQAPFSPPPSPPVQAP--------FSPPASPPVSPSATPPSQA-PPSLA 700

Query: 308 QPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPW 367
            PP   P S P           P   P P     L++ P P   P   PS TP   P   
Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP---PPRV 757

Query: 368 PVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPA 427
           P L   P     P P    P  P   P PQ  P + + PL  L    P+ P       P 
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL----PSPPASFPGQAPF 813

Query: 428 TEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLR 470
           +   SL   PL     +    L    +QV       P+L+  R
Sbjct: 814 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 856



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 18/95 (18%)

Query: 1047 PSPPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLTMPARPPSLPPLLLLPPLIP 1106
            PSPP Q+ +    S      + P   P S A  + + P L +P  PP+       PP+ P
Sbjct: 669  PSPPVQAPFSPPASPP----VSPSATPPSQAPPSLAAPPLQVPPSPPA------SPPMSP 718

Query: 1107 SLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPANP 1141
            S   P QAP        P + +   + PP  PA+P
Sbjct: 719  SATPPPQAP--------PPLAAPPLQVPPSPPASP 745



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 42/151 (27%), Positives = 49/151 (32%), Gaps = 14/151 (9%)

Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELE 345
           P L P  +         A  P Q P   P S P          AP    V  L+      
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668

Query: 346 PVPAL--------GPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQ 397
           P P +         P   PS TP S   P     P+  P   P P    P  P   P PQ
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP---PSPPASPPMSPSATPPPQ 725

Query: 398 GWPRVGSWPLWDLGVLRPTQP--QPSRAPPP 426
             P + + PL  +    P  P   PS  PPP
Sbjct: 726 APPPLAAPPL-QVPPSPPASPPMSPSATPPP 755



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 6/98 (6%)

Query: 1049 PPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLTMPAR----PPSLPPLLLLPPL 1104
            PP Q+    + +  L    CP  CP  +  S  + P    P+     PP  PP L  PPL
Sbjct: 544  PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603

Query: 1105 IPSLRDPQQAPGSTRLSRA-PHIESRVGRKPPEEPANP 1141
               L  P  +P +T   +A P +     + PP  PA+P
Sbjct: 604  -QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 55/205 (26%), Positives = 76/205 (37%), Gaps = 14/205 (6%)

Query: 235 SSPLDLW--QSVEQL----PEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYE-VPE 287
           SSPL +   Q++  L    P+A L+        T++      +Q P    T    E +P 
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540

Query: 288 LLPEGSSAQAVSLSRAQEPAQP-PALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEP 346
           L P      +  L+       P PA  P  AP       P   P +   P  +    L  
Sbjct: 541 LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600

Query: 347 VPALGPVPGPSVTPGSLPAPW-PVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSW 405
            P  G +P P ++P + P P  P    +P   A P P    P  P   P PQ  P   + 
Sbjct: 601 PPLQG-LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA-PNALAV 658

Query: 406 PLWDLGVLRPTQPQPSRAP--PPAT 428
            L       P  P P +AP  PPA+
Sbjct: 659 HLLQAPFSPPPSP-PVQAPFSPPAS 682



 Score = 34.3 bits (77), Expect = 0.69
 Identities = 43/135 (31%), Positives = 49/135 (36%), Gaps = 25/135 (18%)

Query: 304 QEPAQPPALTPE---SAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGP-VPGPSVT 359
           Q P +PP   P+   S P  T   APGP P     P   L          GP + G S +
Sbjct: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS---------GPDLAGHSSS 903

Query: 360 PGSLPAPWPVL--GPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQ 417
             S P        GP     A PPP  +  A       P  W R  + PL   G   P  
Sbjct: 904 ATSTPEELRGYDSGPEGGAAASPPPDAELAACH-----PAAWSRGPAPPLAFRGA--PGA 956

Query: 418 PQPSRAPPPATEFGS 432
           P P    PPAT  GS
Sbjct: 957 PLPW---PPATGPGS 968



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 42/157 (26%), Positives = 56/157 (35%), Gaps = 31/157 (19%)

Query: 336 PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPL 395
           PGL     L P P   P P P VTP +L     VLG   A G +  PL +         +
Sbjct: 22  PGL-----LTPRPPGSPRPPPPVTPAAL----RVLGAAGAVGRK--PLAERAGGIGGATI 70

Query: 396 PQGWPRVGSWPLWDLGVLRPTQPQPS-----RAPP-----------PATEFGSLWPRPLQ 439
           P+  PR G           P    P+     RAPP           P    G+  P PL 
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL- 129

Query: 440 PYQSRQGEALQLAAVQVKGEENDVPSLRGLRERARKD 476
               ++G  +       +G+  + P    L   AR+D
Sbjct: 130 ---GQKGLRISAEETVARGKATEAPKRSALSAGARRD 163



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 39/144 (27%), Positives = 49/144 (34%), Gaps = 24/144 (16%)

Query: 308 QPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPW 367
           +PP +TP              +P   P P    G +  PVP     P  + TP  LPA  
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPS---GTKARPVPP----PDNAATP--LPATL 331

Query: 368 PVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPA 427
           P   P+  P    PP    P   +  P P   P              P+Q  PS   PP 
Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP--------------PSQAPPSMTTPPM 377

Query: 428 TEFGSLWP-RPLQPYQSRQGEALQ 450
               SL    P+Q   S    +LQ
Sbjct: 378 QAPPSLQTIPPIQVPHSLTSPSLQ 401



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 51/206 (24%), Positives = 68/206 (33%), Gaps = 44/206 (21%)

Query: 261 ATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSR--AQEPAQPPALTPESAP 318
           A  ++Q +  + +P L  T   +    + P  + A   S SR  +  P  PP   P S P
Sbjct: 408 ALSSLQATTSLGSPTLQAT---HSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464

Query: 319 GCT---TEFAPGPAPGTEPVPGLELGLELEPVPALGPVPG------------------PS 357
                 T  +P  +P + P       L + P+ AL  +                     S
Sbjct: 465 ASPPLQTSLSPAVSPLSSP-------LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSS 517

Query: 358 VTPGSLPAPWPVLGPVPA---PGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLR 414
           + P SL  P   L   P    P   PPPL    A P   P  +  P     PL       
Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA-PLTTPHLETPPCPAPCPL------- 569

Query: 415 PTQPQPSRAPPPATEFGSLWPRPLQP 440
              P P   PPP T      P P  P
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAP 595



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 32/116 (27%), Positives = 39/116 (33%), Gaps = 5/116 (4%)

Query: 1028 SQRGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCP----RSSACSAASG 1083
            S     P      LAA     PPS      +  SA      PPL      +      AS 
Sbjct: 717  SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776

Query: 1084 PHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIE-SRVGRKPPEEP 1138
            P   +   PP  PP L  PPL      P   PG    S +  +  S +   PP+ P
Sbjct: 777  PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 32/106 (30%), Positives = 38/106 (35%), Gaps = 10/106 (9%)

Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAP-----GPAPGTEPVPGLEL 340
           P   P   +  A++    Q    PPA  P  AP   +   P      P P   PV    L
Sbjct: 780 PLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 839

Query: 341 GLELEPVPALGPV---PGPSVTPG-SLPAPWPVLGPVPAPGAQPPP 382
            L++ P P   P    P    TPG       P L    APG  PPP
Sbjct: 840 -LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884



 Score = 30.8 bits (68), Expect = 7.7
 Identities = 34/124 (27%), Positives = 38/124 (30%), Gaps = 14/124 (11%)

Query: 1028 SQRGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPP-------LCPRSSACSA 1080
            S     P      LAA     PPS      +  SA      PP         P S   S 
Sbjct: 686  SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745

Query: 1081 ASGPHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKP----PE 1136
               P  T P   P +PPLL  PPL      P   P S      P     +   P    P 
Sbjct: 746  PMSPSATPP---PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802

Query: 1137 EPAN 1140
             PA+
Sbjct: 803  PPAS 806


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 32/113 (28%), Positives = 42/113 (37%), Gaps = 6/113 (5%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L P  +     S +    P+  P LTP S P  T    P 
Sbjct: 100 SPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 159

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
             P + P+      L     P L P   P++TP S P   P   P   P ++P
Sbjct: 160 LTPSSRPI------LTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRP 206



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 31/111 (27%), Positives = 38/111 (34%)

Query: 270 PVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPA 329
           P   P    T+     P L P        S +    P+ PP LTP + P  T    P   
Sbjct: 8   PTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLT 67

Query: 330 PGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
           P + P         L P P L     P++TP S P   P   P   P   P
Sbjct: 68  PSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTP 118



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 30/113 (26%), Positives = 38/113 (33%), Gaps = 6/113 (5%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P     +     P L P        S +    P+  P LTP S P  T    P 
Sbjct: 140 STPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 199

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
             P + P+      L     P L P   P +TP S P   P   P+    + P
Sbjct: 200 LTPSSRPI------LTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTP 246



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 31/123 (25%), Positives = 40/123 (32%), Gaps = 10/123 (8%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P     +     P L P  +     S +    P+  P LTP S P  T    P 
Sbjct: 156 STPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 215

Query: 328 PAPGTEPV----------PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPG 377
             P + P+          P     L     P L P   P++TP + P   P   P   P 
Sbjct: 216 LTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPS 275

Query: 378 AQP 380
             P
Sbjct: 276 NTP 278



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 13/93 (13%)

Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365
           P+  P LTP S P  T    P   P ++P+      L     P L P   P++TP + P 
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPI------LTRSSTPTLTPSSPPTLTPSNTPT 57

Query: 366 PWPVLGPVPAPGAQP-------PPLGDWPALPR 391
             P   P   P + P       P L   P L R
Sbjct: 58  LTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTR 90



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 32/113 (28%), Positives = 37/113 (32%), Gaps = 4/113 (3%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P     +     P L P        S +    P+  P LTP S P  T    P 
Sbjct: 22  STPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLT----PS 77

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
             P   P P L         P+  P   PS TP   P+  P L P   P   P
Sbjct: 78  STPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTP 130



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 29/113 (25%), Positives = 38/113 (33%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L    +     S      P+  P LTP + P  T    P 
Sbjct: 14  SPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPT 73

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
             P + P    +  L     P L P   P++TP + P   P   P   P   P
Sbjct: 74  LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTP 126



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 31/115 (26%), Positives = 39/115 (33%), Gaps = 2/115 (1%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L P        S +    P+  P LTP S P  T    P 
Sbjct: 180 STPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPI 239

Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
               + P   P     L     P L P   P++TP + P   P   P   P + P
Sbjct: 240 LTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTP 294



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 31/101 (30%), Positives = 37/101 (36%), Gaps = 6/101 (5%)

Query: 288 LLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEP--VPGLELGLELE 345
           L P  +     S      P+  P LTP S P  T    P   P + P   P     L   
Sbjct: 2   LTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 61

Query: 346 PVPALGPVPGPSVTPGSLP--APWPVLGPVPAPGAQP--PP 382
             P L P   P++TP S P   P P+L     P   P  PP
Sbjct: 62  NTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPP 102



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 31/113 (27%), Positives = 38/113 (33%), Gaps = 2/113 (1%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L    +     S      P+  P LTP S P  T    P 
Sbjct: 188 STPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPT 247

Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGA 378
             P + P   P     L     P L P   P++TP S P   P   P   P +
Sbjct: 248 LTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSS 300



 Score = 37.4 bits (85), Expect = 0.082
 Identities = 29/113 (25%), Positives = 39/113 (34%), Gaps = 4/113 (3%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S+P+       T+     P L P  +     +L+ +  P   P+ TP   P  T    P 
Sbjct: 30  SQPILTRSSTPTLTPSSPPTLTPSNTP----TLTPSNTPTLTPSSTPTLTPSSTPTLTPQ 85

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
           P       P L         P+  P   PS TP   P+  P L P   P   P
Sbjct: 86  PILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTP 138



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 24/96 (25%), Positives = 33/96 (34%), Gaps = 14/96 (14%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P+  P    T+     P L    +     S +    P+  P LTP + P  T    P 
Sbjct: 220 SRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPT 279

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSL 363
             P +               P L P   P++TP SL
Sbjct: 280 LTPSS--------------TPTLTPSSTPTLTPSSL 301


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 32/113 (28%), Positives = 42/113 (37%), Gaps = 6/113 (5%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L P  +     S +    P+  P LTP S P  T    P 
Sbjct: 100 SPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 159

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
             P + P+      L     P L P   P++TP S P   P   P   P ++P
Sbjct: 160 LTPSSRPI------LTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRP 206



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 31/111 (27%), Positives = 38/111 (34%)

Query: 270 PVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPA 329
           P   P    T+     P L P        S +    P+ PP LTP + P  T    P   
Sbjct: 8   PTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLT 67

Query: 330 PGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
           P + P         L P P L     P++TP S P   P   P   P   P
Sbjct: 68  PSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTP 118



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 30/113 (26%), Positives = 38/113 (33%), Gaps = 6/113 (5%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P     +     P L P        S +    P+  P LTP S P  T    P 
Sbjct: 140 STPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 199

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
             P + P+      L     P L P   P +TP S P   P   P+    + P
Sbjct: 200 LTPSSRPI------LTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTP 246



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 31/123 (25%), Positives = 40/123 (32%), Gaps = 10/123 (8%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P     +     P L P  +     S +    P+  P LTP S P  T    P 
Sbjct: 156 STPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 215

Query: 328 PAPGTEPV----------PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPG 377
             P + P+          P     L     P L P   P++TP + P   P   P   P 
Sbjct: 216 LTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPS 275

Query: 378 AQP 380
             P
Sbjct: 276 NTP 278



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 13/93 (13%)

Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365
           P+  P LTP S P  T    P   P ++P+      L     P L P   P++TP + P 
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPI------LTRSSTPTLTPSSPPTLTPSNTPT 57

Query: 366 PWPVLGPVPAPGAQP-------PPLGDWPALPR 391
             P   P   P + P       P L   P L R
Sbjct: 58  LTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTR 90



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 32/113 (28%), Positives = 37/113 (32%), Gaps = 4/113 (3%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P     +     P L P        S +    P+  P LTP S P  T    P 
Sbjct: 22  STPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLT----PS 77

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
             P   P P L         P+  P   PS TP   P+  P L P   P   P
Sbjct: 78  STPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTP 130



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 29/113 (25%), Positives = 38/113 (33%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L    +     S      P+  P LTP + P  T    P 
Sbjct: 14  SPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPT 73

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
             P + P    +  L     P L P   P++TP + P   P   P   P   P
Sbjct: 74  LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTP 126



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 31/115 (26%), Positives = 39/115 (33%), Gaps = 2/115 (1%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L P        S +    P+  P LTP S P  T    P 
Sbjct: 180 STPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPI 239

Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
               + P   P     L     P L P   P++TP + P   P   P   P + P
Sbjct: 240 LTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTP 294



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 31/101 (30%), Positives = 37/101 (36%), Gaps = 6/101 (5%)

Query: 288 LLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEP--VPGLELGLELE 345
           L P  +     S      P+  P LTP S P  T    P   P + P   P     L   
Sbjct: 2   LTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 61

Query: 346 PVPALGPVPGPSVTPGSLP--APWPVLGPVPAPGAQP--PP 382
             P L P   P++TP S P   P P+L     P   P  PP
Sbjct: 62  NTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPP 102



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 31/113 (27%), Positives = 38/113 (33%), Gaps = 2/113 (1%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L    +     S      P+  P LTP S P  T    P 
Sbjct: 188 STPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPT 247

Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGA 378
             P + P   P     L     P L P   P++TP S P   P   P   P +
Sbjct: 248 LTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSS 300



 Score = 37.4 bits (85), Expect = 0.082
 Identities = 29/113 (25%), Positives = 39/113 (34%), Gaps = 4/113 (3%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S+P+       T+     P L P  +     +L+ +  P   P+ TP   P  T    P 
Sbjct: 30  SQPILTRSSTPTLTPSSPPTLTPSNTP----TLTPSNTPTLTPSSTPTLTPSSTPTLTPQ 85

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
           P       P L         P+  P   PS TP   P+  P L P   P   P
Sbjct: 86  PILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTP 138



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 24/96 (25%), Positives = 33/96 (34%), Gaps = 14/96 (14%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P+  P    T+     P L    +     S +    P+  P LTP + P  T    P 
Sbjct: 220 SRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPT 279

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSL 363
             P +               P L P   P++TP SL
Sbjct: 280 LTPSS--------------TPTLTPSSTPTLTPSSL 301


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 62/208 (29%), Positives = 80/208 (38%), Gaps = 44/208 (21%)

Query: 293 SSAQAVSLSRAQEPAQPPA------------LTPESAPGCTTEFAPGPAPG----TEPVP 336
           SS Q+V L    + A  PA            + P+S P       P  APG    + P P
Sbjct: 630 SSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAP 689

Query: 337 GLELGLELE-PVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPR-RWP 394
                L+   P PA+   P   + P S P P     P P PG QPPPL     LP+   P
Sbjct: 690 ACPPSLQQHFPDPAMSFAP--VLPPPSTPMPTGPGQPAP-PGQQPPPLAQPTPLPQVLAP 746

Query: 395 LPQGWPRVGSWPLWDLGVLRPTQPQPSRAPP---PATEFGSLWPRPLQPYQSRQGEALQL 451
            P                + P QP P   PP   PA++ G+  P  L+P Q  Q     L
Sbjct: 747 QP----------------VVPLQPVPPHLPPYLAPASQVGA--PAQLKPLQMPQAPLQPL 788

Query: 452 AAVQVKGEENDVPSLRGLRERARKDGAP 479
           A  QV  +   +P +  +   A  DG P
Sbjct: 789 A--QVPPQMPPIPVVPPITPLAGIDGLP 814



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 55/174 (31%), Positives = 66/174 (37%), Gaps = 42/174 (24%)

Query: 290  PEGSSAQAVSLSRAQEPAQP--PALTPESAPGCTTEFAPGP------------APGTEPV 335
            P G +A ++  + AQ P QP  PA  P+ AP   T+  P P             P   P 
Sbjct: 891  PPGVAALSIHSAVAQLPGQPVYPAAFPQMAP---TDVPPSPHHTVQNMRATPPQPALPPQ 947

Query: 336  PGLELGLELEPVPALGPVP----------GPSVTPGSLPAPWPVLGPVPAPGAQPPPLGD 385
            P L     L P P L P P           P + P  +  P PVL P PA   +P PL  
Sbjct: 948  PTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPL-- 1005

Query: 386  WPALPRRWPLPQGWPRVGSWPLW--------DLGVLRPTQPQPSRA--PPPATE 429
             P LP +   P   P  GS  L         D+    PT P P  A   PP  E
Sbjct: 1006 QPHLPEQ-AAPAATP--GSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPE 1056



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 38/134 (28%), Positives = 52/134 (38%), Gaps = 21/134 (15%)

Query: 286 PELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELE 345
           P  LP+  + Q V   +   P  PP L P S  G   +  P   P     P  ++  ++ 
Sbjct: 737 PTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMP 796

Query: 346 PVPALGPV---PGPSVTPGSLP-APWPVLGPVPAP------------GAQPPPLGDWPAL 389
           P+P + P+    G    P +LP  P   + PVP P             A  PP    PAL
Sbjct: 797 PIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPAS--PAL 854

Query: 390 PR---RWPLPQGWP 400
           P    + P P G P
Sbjct: 855 PLQAVKLPHPPGAP 868



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 32/93 (34%), Positives = 41/93 (44%), Gaps = 12/93 (12%)

Query: 290  PEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPA 349
            PE +S +  S  R  EP  PPA  PE +P   T   P PA G +P P L   +    + A
Sbjct: 1460 PEAASTRDASAPR--EPLPPPA--PEPSPHSGT---PQPALG-QPAPLLPAAVGAVSL-A 1510

Query: 350  LGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382
               +P P + P   P P   L    + G  PPP
Sbjct: 1511 TSQLPSPPLGPTVPPQPPSAL---ESDGEGPPP 1540



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 38/140 (27%), Positives = 46/140 (32%), Gaps = 25/140 (17%)

Query: 306  PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365
            P  PPA    S+P  T     G AP T  +P        EP        G   TP  L +
Sbjct: 1377 PGAPPAPLAPSSPPVTALPQDGAAPATSTMP--------EPASGTASQAGGPGTPQGLTS 1428

Query: 366  PWPVLGPV----PAP-GAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQP 420
                  P+     AP   QP  +G  P  P         P   S          P +P P
Sbjct: 1429 ELETSQPLAETHEAPLAVQPLVVGLAPCTPA--------PEAAS----TRDASAPREPLP 1476

Query: 421  SRAPPPATEFGSLWPRPLQP 440
              AP P+   G+  P   QP
Sbjct: 1477 PPAPEPSPHSGTPQPALGQP 1496


>gi|50428940 mediator complex subunit 25 [Homo sapiens]
          Length = 747

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 47/140 (33%), Positives = 57/140 (40%), Gaps = 25/140 (17%)

Query: 278 QTVWHYEVPELLPEGS--SAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPV 335
           Q +     P+  P+G+  ++ A    + Q  AQPP   P+  PG  +   P P P   P 
Sbjct: 580 QNLLQLRPPQPQPQGTVGASGATGQPQPQGTAQPPPGAPQGPPGAASG-PPPPGPILRPQ 638

Query: 336 -PGLE---LGLELEPVPALGPVPGPSVT---------PGSLPAP-----WPVLGPVPAPG 377
            PG       L L P P    VP P  +         P  LP P      P LGP   P 
Sbjct: 639 NPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGP---PL 695

Query: 378 AQPPPLGDWPA-LPRRWPLP 396
             PPP   WPA LP R PLP
Sbjct: 696 LHPPPAQSWPAQLPPRAPLP 715



 Score = 37.4 bits (85), Expect = 0.082
 Identities = 47/154 (30%), Positives = 61/154 (39%), Gaps = 31/154 (20%)

Query: 234 GSSPLDLWQSVEQLPEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGS 293
           GS+P  L QS + +P    A +   L A  A Q   P   PQ       Y+VP  L    
Sbjct: 233 GSAPGPL-QSKQPVPLPPAAPSGATLSA--APQQPLPPVPPQ-------YQVPGNLSAAQ 282

Query: 294 SA--QAVSLSRAQEPAQPPALTP-----ESAPGCTTEFAPGPAPGTEPVPGLELGLELEP 346
            A   AV  ++ Q+    P  +P     ++APG    F+  PAP            +L P
Sbjct: 283 VAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPAP------------QLPP 330

Query: 347 VPALGPVPGPSVTPG--SLPAPWPVLGPVPAPGA 378
            P   P P P+  P   S  AP   L P   PGA
Sbjct: 331 GPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGA 364



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 35/111 (31%), Positives = 44/111 (39%), Gaps = 14/111 (12%)

Query: 286 PELLPE--GSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLE 343
           P L P+  G++ Q  SL     P Q     P+++        P  AP   P P   LG  
Sbjct: 633 PILRPQNPGANPQLRSLLLNPPPPQTGVPPPQAS---LHHLQPPGAPALLPPPHQGLGQP 689

Query: 344 LEPVPALGPVPG---PSVTPGSLPAPWPVL------GPVPAPGAQPPPLGD 385
               P L P P    P+  P   P P  +L      GPVP PG QP  + D
Sbjct: 690 QLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMED 740



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 30/111 (27%), Positives = 39/111 (35%), Gaps = 8/111 (7%)

Query: 274 PQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTE 333
           P  LQ+     +P   P G++     LS A +   PP       PG  +          E
Sbjct: 236 PGPLQSKQPVPLPPAAPSGAT-----LSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVE 290

Query: 334 PVPGLELGL--ELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382
                + GL     P+  L     P V P    AP P L P P    +PPP
Sbjct: 291 AAKNQKAGLGPRFSPITPLQQA-APGVGPPFSQAPAPQLPPGPPGAPKPPP 340


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 76/310 (24%), Positives = 114/310 (36%), Gaps = 60/310 (19%)

Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPG---------- 355
           P  PP + P S P       P   P T P PG+   +    +P   P PG          
Sbjct: 531 PTMPPPVLPPSLP---PPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGP 587

Query: 356 -PSVTPGSLPA--PWPVLGPVPAPGAQPPPLGDWPALPRRWP--------LPQGW-PRVG 403
            P + P SL +  P PVL P       PPP+   P L    P        +PQG  P++ 
Sbjct: 588 PPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLT 647

Query: 404 SWPLWDLGVLR----PTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGE 459
           + P+      +    P +P+P+  P P + FGS  P    P     G + Q+ +     +
Sbjct: 648 AAPVPPASSSQSSQVPEKPRPALLPTPVS-FGSAPPTTYHPPLQSAGPSEQVNSKAPLSK 706

Query: 460 E----NDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDP-------KDRAHKDDV 508
                +   S +GL E +     P   T    +P   GG   DP         R  + D 
Sbjct: 707 SALPYSSFSSDQGLGESSAAPSQP--ITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDG 764

Query: 509 PK---DRGGKDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEAQ-------PKAPQ 558
           P+   D G +   P+ +      P+  G +   P+ R   +G P E         P+ P 
Sbjct: 765 PRRFEDLGSRCEGPRPKG-----PRFEGNRPDGPRPRY--EGHPAEGTKSKWGMIPRGPA 817

Query: 559 SALHRLKTTA 568
           S  +   +T+
Sbjct: 818 SQFYITPSTS 827



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 43/153 (28%), Positives = 57/153 (37%), Gaps = 37/153 (24%)

Query: 295 AQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVP 354
           AQ   L +  +      L P   P       P P P    +PG   G    P P + P P
Sbjct: 59  AQLQQLQQMHQKQMQCVLQPHHLP-------PPPLPPPPVMPGGGYGDWQPPPPPMPPPP 111

Query: 355 GPSVT-------------------PGSLPAPW---PVLGPVPAPGAQPPPLGDWPALPRR 392
           GP+++                   PG +P      P   PVP PG+  PP   +  +P  
Sbjct: 112 GPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVP-PGSYMPPSQSY--MPPP 168

Query: 393 WPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPP 425
            P P  +P   S P      L P QP PS++PP
Sbjct: 169 QPPPSYYPPTSSQP-----YLPPAQPSPSQSPP 196



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 33/101 (32%), Positives = 39/101 (38%), Gaps = 7/101 (6%)

Query: 353 VPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGV 412
           +P P V    +P P P + P   P + PPP+   PALP   P P G P     P     V
Sbjct: 516 MPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMP-PALPATVP-PPGMPPPVMPPSLPTSV 573

Query: 413 LRPTQPQ--PSRAPPPA---TEFGSLWPRPLQPYQSRQGEA 448
             P  P    S  PPP        S  P P+ P  S    A
Sbjct: 574 PPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTA 614



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 60/256 (23%), Positives = 89/256 (34%), Gaps = 51/256 (19%)

Query: 330  PGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA---------PWPVLGPVPAPGAQP 380
            PG  P PG        P P +G  PG  V P + PA         P P+  P P P   P
Sbjct: 1503 PGMYPPPG-----SYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPP 1557

Query: 381  PPLGDWPAL-PRRWPLPQ-GWPRVGSWPLWDLGVLRPTQ----------PQPSRAPPPAT 428
            PP    P + P+   + Q  W     + LWD    +             P     PPP  
Sbjct: 1558 PP----PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPV 1613

Query: 429  EFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLR------GLRERARKDGAPKDR 482
                  P P+        +   +      G   D+ + +      G R   R D  P+  
Sbjct: 1614 HSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERS 1673

Query: 483  T-------RKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGGK 535
            T       ++D   ++R   D +P      + +   R  K    +DR    D  +DRG  
Sbjct: 1674 TFETEHAGQRDRYDRER---DREPYFDRQSNVIADHRDFK----RDRETHRDRDRDRGVI 1726

Query: 536  DGDPKDRVGKDGAPKE 551
            D D +DR  ++  P++
Sbjct: 1727 DYD-RDRFDRERRPRD 1741



 Score = 34.3 bits (77), Expect = 0.69
 Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 17/83 (20%)

Query: 1069 PPLCPRSSACSAASGPHLTMPARPPSL-----PPLLLLPPL--------IPSLRDPQQAP 1115
            PP+ P  S  SA  GP   +P  PPSL     PP++ LPPL        IP    PQ  P
Sbjct: 588  PPVLPPPSLSSA--GPPPVLP--PPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIP 643

Query: 1116 GSTRLSRAPHIESRVGRKPPEEP 1138
                 +  P   S    + PE+P
Sbjct: 644  PQLTAAPVPPASSSQSSQVPEKP 666



 Score = 30.8 bits (68), Expect = 7.7
 Identities = 53/198 (26%), Positives = 70/198 (35%), Gaps = 31/198 (15%)

Query: 339  ELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP---PPLGDWPALPRRWPL 395
            E GL  E       +P   V P     P PV   +P PG  P   PP+   P + +    
Sbjct: 1588 EQGLNSEFKSETAAIPSAPVLP-----PPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDY 1642

Query: 396  PQGWP----RVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSL----WPRPLQPYQSRQGE 447
              G      +V   P  +   LRP  P P R+       G        R  +PY  RQ  
Sbjct: 1643 GHGRDISTNKVEQIPYGERITLRP-DPLPERSTFETEHAGQRDRYDRERDREPYFDRQSN 1701

Query: 448  ALQLAAVQVKGEEN--DVPSLRGL----RERARKDGAPKD------RTRKDGVPKDRGGK 495
             +       +  E   D    RG+    R+R  ++  P+D      R +KD     RGG 
Sbjct: 1702 VIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQSYRDKKDHSSSRRGGF 1761

Query: 496  DVDPKDRAHKDDVPKDRG 513
            D    DR  K D P   G
Sbjct: 1762 DRPSYDR--KSDRPVYEG 1777


>gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 280

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 33/115 (28%), Positives = 41/115 (35%), Gaps = 2/115 (1%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L P  +     S +    P+  P LTP S P  T    P 
Sbjct: 114 STPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 173

Query: 328 PAPGTEP--VPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
             P + P   P     L     P L P   P++TP S P   P   P   P + P
Sbjct: 174 LTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTP 228



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 33/115 (28%), Positives = 42/115 (36%), Gaps = 2/115 (1%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L P  +     S +    P+  P LTP S P  T    P 
Sbjct: 74  STPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 133

Query: 328 PAPGTEPVPGLELGLELEP--VPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
             P + P         L P   P L P   P++TP S P   P   P   P ++P
Sbjct: 134 LTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRP 188



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 31/115 (26%), Positives = 41/115 (35%), Gaps = 2/115 (1%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L    +     S +    P+  P LTP S P  T    P 
Sbjct: 122 STPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 181

Query: 328 PAPGTEPVPGLELGLELEP--VPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
             P + P+        L P   P L P   P++TP + P   P   P   P + P
Sbjct: 182 LTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTP 236



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 33/123 (26%), Positives = 41/123 (33%), Gaps = 10/123 (8%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L P  +     S +    P+  P LTP S P  T    P 
Sbjct: 58  SPPTLTPSNTPTLTPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPT 117

Query: 328 PAPGTEP----------VPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPG 377
             P + P           P     L     P L P   P++TP S P   P   P   P 
Sbjct: 118 LTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPS 177

Query: 378 AQP 380
           + P
Sbjct: 178 STP 180



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 31/115 (26%), Positives = 40/115 (34%), Gaps = 2/115 (1%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L P  +     S +    P+  P LTP S P  T    P 
Sbjct: 130 STPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPI 189

Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
               + P   P     L     P L P   P++ P S P   P   P   P ++P
Sbjct: 190 LTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRP 244



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 30/117 (25%), Positives = 40/117 (34%), Gaps = 2/117 (1%)

Query: 266 QVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFA 325
           ++  P   P    T+     P L P  +       +    P+  P LTP S P  T    
Sbjct: 48  EMGTPTLTPSSPPTLTPSNTPTLTPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSST 107

Query: 326 PGPAPGTEP--VPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQP 380
           P   P + P   P     L     P L P   P++T  S P   P   P   P + P
Sbjct: 108 PTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTP 164



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 33/119 (27%), Positives = 41/119 (34%), Gaps = 6/119 (5%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L P  +     S +    P+  P LT  S P  T    P 
Sbjct: 146 STPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPT 205

Query: 328 PAPGTEPV--PGLELGLELEPVPALGPVPGPSVTPGSLP----APWPVLGPVPAPGAQP 380
             P + P   P     L     P L P   P++TP S P    +  P L P   P   P
Sbjct: 206 LTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTP 264



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 27/101 (26%), Positives = 34/101 (33%), Gaps = 6/101 (5%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P     +     P L P  +     S +    P+  P L P S P  T    P 
Sbjct: 178 STPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPT 237

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWP 368
             P + P       L     P L P   P++TP S P   P
Sbjct: 238 LTPSSRPT------LTRSSTPTLTPSSTPTLTPSSTPTLTP 272



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 14/96 (14%)

Query: 268 SEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPG 327
           S P   P    T+     P L P  +     S +    P+  P LTP S P  T    P 
Sbjct: 194 STPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPT 253

Query: 328 PAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSL 363
             P +               P L P   P++TP SL
Sbjct: 254 LTPSS--------------TPTLTPSSTPTLTPSSL 275


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 45/180 (25%), Positives = 62/180 (34%), Gaps = 5/180 (2%)

Query: 306 PAQPPAL---TPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGS 362
           PA+PP     TP+         +P  APG    P  + G    P    GP    +   G 
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466

Query: 363 LPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSR 422
              P  + GP   P  QP P    P  P     P   P     P    G  +P+  QP  
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526

Query: 423 APPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDV--PSLRGLRERARKDGAPK 480
             PP+ + GS  P   QP  ++         V   G    +  P++    ++    G PK
Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 65/262 (24%), Positives = 85/262 (32%), Gaps = 38/262 (14%)

Query: 303 AQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALG------PVPGP 356
           A+ PAQP  LT   A    T   P   PGT   P   LG    P    G        PGP
Sbjct: 329 AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388

Query: 357 SV---TPGSLPAPWPVLGPVPAPGAQ---PPPLGDWPAL--------PRRWPLPQGWP-- 400
                 PG    P    GP   P  Q   P PL   P L        P + P+ Q  P  
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448

Query: 401 ------RVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAV 454
                   G       G  +P    P  A PP  + G   P P QP  ++          
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS------- 501

Query: 455 QVKGEENDVPSLRG-LRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDR- 512
           Q  G     P   G  +   ++ G+ K  +++ G  K    +    K  A +   P  + 
Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561

Query: 513 -GGKDVDPKDRAHKDDVPKDRG 533
             GK + P   +     P  +G
Sbjct: 562 GSGKPLQPPTVSPSAKQPPSQG 583



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 42/159 (26%), Positives = 56/159 (35%), Gaps = 23/159 (14%)

Query: 289 LPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVP 348
           L   + A   + +  Q+P        ++ PG T+    GP      +PG       +P  
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP-- 484

Query: 349 ALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLW 408
             GP   P   PGS   P    G    P  QP P    P  P     P   P        
Sbjct: 485 --GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP-------- 534

Query: 409 DLGVLRPTQPQPSRAPP-------PATEFGSLWPRPLQP 440
             G  +P+  QPS A P       P ++ GS   +PLQP
Sbjct: 535 --GSAKPSAQQPSPAKPSAQQSTKPVSQTGS--GKPLQP 569



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 65/269 (24%), Positives = 91/269 (33%), Gaps = 40/269 (14%)

Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365
           P +PPA  P           PGPA       GL   L  +P    G V  P   PG+   
Sbjct: 311 PGKPPAQQPGHEKS-----QPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQPPGTTKP 361

Query: 366 PWPVLGPVPAPGAQ---PPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSR 422
           P   LGP   P  Q     P  + P  P+    P   P VG  P            QP  
Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPG-PKALAQP---PGVGKTP----------AQQPGP 407

Query: 423 APPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEE---NDVPSLRG--LRERARKDG 477
           A PP  + G+  P+PL      Q  A      +   ++     +P+ +    +  A++ G
Sbjct: 408 AKPPTQQVGT--PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465

Query: 478 APKDRTRKDG---VPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGG 534
             K  ++  G    P  + G    P  +      P  + G    P  +         + G
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525

Query: 535 KDGDPKDRVG--KDGA--PKEAQPKAPQS 559
               P  + G  K  A  P  A+P A QS
Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQS 554



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 56/238 (23%), Positives = 81/238 (34%), Gaps = 26/238 (10%)

Query: 225  HDAMFTSEIGSSPLDLWQSVEQLPEAALAQTTKYLEATRAIQVSEPVQ-------NPQLL 277
            H  +  S++ SS ++   SV   PE  +A T   +     I   +PV+       N  +L
Sbjct: 2261 HIVISLSDMASSIIE---SVVPKPEGPVADT---VSTDLLISEKDPVKKAKKETGNGIIL 2314

Query: 278  QTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPG 337
            + +  Y   + L    +  ++S +    P       P      TT F  G   G E  P 
Sbjct: 2315 EVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEK-PA 2373

Query: 338  LELGLELEPVPALGPVPGPSVTPGSL------------PAPWPVLGPVPAPGAQPPPLGD 385
             +L      V +L   P P     SL            P P P   P P P   PPP   
Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433

Query: 386  WPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQS 443
             P +  +  L    P   + PL+D      T         P T   +  P P+ P  S
Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 45/180 (25%), Positives = 62/180 (34%), Gaps = 5/180 (2%)

Query: 306 PAQPPAL---TPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGS 362
           PA+PP     TP+         +P  APG    P  + G    P    GP    +   G 
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466

Query: 363 LPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSR 422
              P  + GP   P  QP P    P  P     P   P     P    G  +P+  QP  
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526

Query: 423 APPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDV--PSLRGLRERARKDGAPK 480
             PP+ + GS  P   QP  ++         V   G    +  P++    ++    G PK
Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 65/262 (24%), Positives = 85/262 (32%), Gaps = 38/262 (14%)

Query: 303 AQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALG------PVPGP 356
           A+ PAQP  LT   A    T   P   PGT   P   LG    P    G        PGP
Sbjct: 329 AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388

Query: 357 SV---TPGSLPAPWPVLGPVPAPGAQ---PPPLGDWPAL--------PRRWPLPQGWP-- 400
                 PG    P    GP   P  Q   P PL   P L        P + P+ Q  P  
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448

Query: 401 ------RVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAV 454
                   G       G  +P    P  A PP  + G   P P QP  ++          
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS------- 501

Query: 455 QVKGEENDVPSLRG-LRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDR- 512
           Q  G     P   G  +   ++ G+ K  +++ G  K    +    K  A +   P  + 
Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561

Query: 513 -GGKDVDPKDRAHKDDVPKDRG 533
             GK + P   +     P  +G
Sbjct: 562 GSGKPLQPPTVSPSAKQPPSQG 583



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 42/159 (26%), Positives = 56/159 (35%), Gaps = 23/159 (14%)

Query: 289 LPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVP 348
           L   + A   + +  Q+P        ++ PG T+    GP      +PG       +P  
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP-- 484

Query: 349 ALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLW 408
             GP   P   PGS   P    G    P  QP P    P  P     P   P        
Sbjct: 485 --GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP-------- 534

Query: 409 DLGVLRPTQPQPSRAPP-------PATEFGSLWPRPLQP 440
             G  +P+  QPS A P       P ++ GS   +PLQP
Sbjct: 535 --GSAKPSAQQPSPAKPSAQQSTKPVSQTGS--GKPLQP 569



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 65/269 (24%), Positives = 91/269 (33%), Gaps = 40/269 (14%)

Query: 306 PAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPA 365
           P +PPA  P           PGPA       GL   L  +P    G V  P   PG+   
Sbjct: 311 PGKPPAQQPGHEKS-----QPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQPPGTTKP 361

Query: 366 PWPVLGPVPAPGAQ---PPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSR 422
           P   LGP   P  Q     P  + P  P+    P   P VG  P            QP  
Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPG-PKALAQP---PGVGKTP----------AQQPGP 407

Query: 423 APPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEE---NDVPSLRG--LRERARKDG 477
           A PP  + G+  P+PL      Q  A      +   ++     +P+ +    +  A++ G
Sbjct: 408 AKPPTQQVGT--PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465

Query: 478 APKDRTRKDG---VPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGG 534
             K  ++  G    P  + G    P  +      P  + G    P  +         + G
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525

Query: 535 KDGDPKDRVG--KDGA--PKEAQPKAPQS 559
               P  + G  K  A  P  A+P A QS
Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQS 554



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 56/238 (23%), Positives = 81/238 (34%), Gaps = 26/238 (10%)

Query: 225  HDAMFTSEIGSSPLDLWQSVEQLPEAALAQTTKYLEATRAIQVSEPVQ-------NPQLL 277
            H  +  S++ SS ++   SV   PE  +A T   +     I   +PV+       N  +L
Sbjct: 2261 HIVISLSDMASSIIE---SVVPKPEGPVADT---VSTDLLISEKDPVKKAKKETGNGIIL 2314

Query: 278  QTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPG 337
            + +  Y   + L    +  ++S +    P       P      TT F  G   G E  P 
Sbjct: 2315 EVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEK-PA 2373

Query: 338  LELGLELEPVPALGPVPGPSVTPGSL------------PAPWPVLGPVPAPGAQPPPLGD 385
             +L      V +L   P P     SL            P P P   P P P   PPP   
Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433

Query: 386  WPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQS 443
             P +  +  L    P   + PL+D      T         P T   +  P P+ P  S
Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 54/186 (29%), Positives = 62/186 (33%), Gaps = 35/186 (18%)

Query: 266 QVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPP--ALTPESAPGCTTE 323
           Q   P Q P   Q   H   P   P           + Q+P  PP  +  P  A G    
Sbjct: 69  QQQPPPQQPPPQQPPPHQPPPHPQPH----------QQQQPPPPPQDSSKPVVAQG---- 114

Query: 324 FAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGA----- 378
             PGPAPG    P           P  G  PG    PG  P P P +   P PGA     
Sbjct: 115 --PGPAPGVGSAPPASSSAPPATPPTSGAPPGSG--PGPTPTPPPAVTSAP-PGAPPPTP 169

Query: 379 -------QPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFG 431
                   PP  G  P  P   P P   P+ G  P    G   P  P+P   P  +T  G
Sbjct: 170 PSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGG 229

Query: 432 SLWPRP 437
              P+P
Sbjct: 230 H--PKP 233



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 31/90 (34%), Positives = 35/90 (38%), Gaps = 11/90 (12%)

Query: 293 SSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGP 352
           SS    +  +A  P  PPA  P           PGP P   P PG   G ++   P  G 
Sbjct: 171 SSGVPTTPPQAGGPPPPPAAVP----------GPGPGPKQGPGPGGPKGGKMPGGPKPGG 220

Query: 353 VPGPSVTPGSLPAPWPVLGPVPAPGAQPPP 382
            PG S TPG  P P    G  P  G Q  P
Sbjct: 221 GPGLS-TPGGHPKPPHRGGGEPRGGRQHHP 249



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 9/102 (8%)

Query: 334 PVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRW 393
           P PG+ L     P   +GP PG S     +P P P       P  QPPP    P  P   
Sbjct: 34  PPPGMGLNQNRGP---MGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPH 90

Query: 394 PLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWP 435
           P P    +    P         ++P  ++ P PA   GS  P
Sbjct: 91  PQPHQQQQPPPPP------QDSSKPVVAQGPGPAPGVGSAPP 126


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,317,396
Number of Sequences: 37866
Number of extensions: 2914677
Number of successful extensions: 23652
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 1102
Number of HSP's that attempted gapping in prelim test: 14641
Number of HSP's gapped (non-prelim): 6230
length of query: 1141
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1028
effective length of database: 13,968,660
effective search space: 14359782480
effective search space used: 14359782480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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