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Search of human proteins with 22094987
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22094987 raptor isoform 1 [Homo sapiens]
(1335 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22094987 raptor isoform 1 [Homo sapiens] 2706 0.0
gi|251823858 raptor isoform 2 [Homo sapiens] 1360 0.0
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 54 1e-06
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 51 6e-06
gi|26665869 WD repeat domain 51B [Homo sapiens] 50 1e-05
gi|148727341 serine/threonine kinase receptor associated protein... 49 2e-05
gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)... 47 2e-04
gi|223005862 echinoderm microtubule associated protein like 6 [H... 45 4e-04
gi|34485720 echinoderm microtubule associated protein like 5 [Ho... 44 0.001
gi|89886480 zinedin isoform 2 [Homo sapiens] 42 0.003
gi|89886477 zinedin isoform 1 [Homo sapiens] 42 0.003
gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1... 42 0.004
gi|50980309 UTP15, U3 small nucleolar ribonucleoprotein, homolog... 41 0.007
gi|16554629 WD repeat domain 5 [Homo sapiens] 41 0.009
gi|16554627 WD repeat domain 5 [Homo sapiens] 41 0.009
gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 41 0.009
gi|124256480 APG16 autophagy 16-like isoform 1 [Homo sapiens] 40 0.011
gi|124256478 APG16 autophagy 16-like isoform 2 [Homo sapiens] 40 0.011
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 40 0.015
gi|148536855 coatomer protein complex, subunit alpha isoform 1 [... 39 0.026
gi|148536853 coatomer protein complex, subunit alpha isoform 2 [... 39 0.026
gi|157502169 astacin-like metalloendopeptidase [Homo sapiens] 39 0.026
gi|221219004 WD repeat domain 74 [Homo sapiens] 39 0.033
gi|13129110 WD repeat domain 77 [Homo sapiens] 39 0.033
gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] 38 0.074
gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [... 38 0.074
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 37 0.13
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 37 0.13
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 37 0.13
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 37 0.13
>gi|22094987 raptor isoform 1 [Homo sapiens]
Length = 1335
Score = 2706 bits (7014), Expect = 0.0
Identities = 1335/1335 (100%), Positives = 1335/1335 (100%)
Query: 1 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV 60
MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV
Sbjct: 1 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV 60
Query: 61 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK 120
ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK
Sbjct: 61 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK 120
Query: 121 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY 180
QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY
Sbjct: 121 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY 180
Query: 181 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC 240
DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC
Sbjct: 181 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC 240
Query: 241 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG 300
IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG
Sbjct: 241 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG 300
Query: 301 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY 360
RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY
Sbjct: 301 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY 360
Query: 361 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL 420
NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL
Sbjct: 361 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL 420
Query: 421 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL 480
TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL
Sbjct: 421 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL 480
Query: 481 QSSARELRPLLVFIWAKILAVDSSCQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILA 540
QSSARELRPLLVFIWAKILAVDSSCQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILA
Sbjct: 481 QSSARELRPLLVFIWAKILAVDSSCQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILA 540
Query: 541 VIVNSYHTGQEACLQGNLIAICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSA 600
VIVNSYHTGQEACLQGNLIAICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSA
Sbjct: 541 VIVNSYHTGQEACLQGNLIAICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSA 600
Query: 601 HEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERTDHSTTIDHNVAMMLAQLVSDGSPMVR 660
HEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERTDHSTTIDHNVAMMLAQLVSDGSPMVR
Sbjct: 601 HEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERTDHSTTIDHNVAMMLAQLVSDGSPMVR 660
Query: 661 KELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV 720
KELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV
Sbjct: 661 KELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV 720
Query: 721 SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS 780
SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS
Sbjct: 721 SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS 780
Query: 781 FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK 840
FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK
Sbjct: 781 FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK 840
Query: 841 ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD 900
ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD
Sbjct: 841 ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD 900
Query: 901 LPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC 960
LPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC
Sbjct: 901 LPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC 960
Query: 961 DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN 1020
DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN
Sbjct: 961 DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN 1020
Query: 1021 RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD 1080
RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD
Sbjct: 1021 RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD 1080
Query: 1081 CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS 1140
CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS
Sbjct: 1081 CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS 1140
Query: 1141 SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS 1200
SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS
Sbjct: 1141 SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS 1200
Query: 1201 ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD 1260
ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD
Sbjct: 1201 ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD 1260
Query: 1261 IHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS 1320
IHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS
Sbjct: 1261 IHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS 1320
Query: 1321 NDYYISVYSVEKRVR 1335
NDYYISVYSVEKRVR
Sbjct: 1321 NDYYISVYSVEKRVR 1335
>gi|251823858 raptor isoform 2 [Homo sapiens]
Length = 1177
Score = 1360 bits (3520), Expect = 0.0
Identities = 675/677 (99%), Positives = 675/677 (99%)
Query: 659 VRKELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLR 718
V ELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLR
Sbjct: 501 VDSELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLR 560
Query: 719 SVSSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHI 778
SVSSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHI
Sbjct: 561 SVSSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHI 620
Query: 779 LSFETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIA 838
LSFETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIA
Sbjct: 621 LSFETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIA 680
Query: 839 YKATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVS 898
YKATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVS
Sbjct: 681 YKATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVS 740
Query: 899 RDLPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTG 958
RDLPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTG
Sbjct: 741 RDLPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTG 800
Query: 959 FCDWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIF 1018
FCDWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIF
Sbjct: 801 FCDWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIF 860
Query: 1019 LNRNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNG 1078
LNRNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNG
Sbjct: 861 LNRNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNG 920
Query: 1079 QDCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLL 1138
QDCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLL
Sbjct: 921 QDCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLL 980
Query: 1139 MSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMA 1198
MSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMA
Sbjct: 981 MSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMA 1040
Query: 1199 LSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTA 1258
LSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTA
Sbjct: 1041 LSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTA 1100
Query: 1259 LDIHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAV 1318
LDIHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAV
Sbjct: 1101 LDIHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAV 1160
Query: 1319 GSNDYYISVYSVEKRVR 1335
GSNDYYISVYSVEKRVR
Sbjct: 1161 GSNDYYISVYSVEKRVR 1177
Score = 1027 bits (2655), Expect = 0.0
Identities = 503/503 (100%), Positives = 503/503 (100%)
Query: 1 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV 60
MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV
Sbjct: 1 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV 60
Query: 61 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK 120
ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK
Sbjct: 61 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK 120
Query: 121 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY 180
QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY
Sbjct: 121 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY 180
Query: 181 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC 240
DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC
Sbjct: 181 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC 240
Query: 241 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG 300
IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG
Sbjct: 241 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG 300
Query: 301 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY 360
RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY
Sbjct: 301 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY 360
Query: 361 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL 420
NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL
Sbjct: 361 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL 420
Query: 421 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL 480
TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL
Sbjct: 421 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL 480
Query: 481 QSSARELRPLLVFIWAKILAVDS 503
QSSARELRPLLVFIWAKILAVDS
Sbjct: 481 QSSARELRPLLVFIWAKILAVDS 503
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 53.5 bits (127), Expect = 1e-06
Identities = 73/319 (22%), Positives = 126/319 (39%), Gaps = 43/319 (13%)
Query: 1017 IFLNRNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYL 1076
+ L+ + G KFHP +A A D + W D + V + Y
Sbjct: 60 MLLSGHEGEVYCCKFHPNGSTLASAGFDRLILL-WNVYGDCDNYATLKGHSGAVMELHY- 117
Query: 1077 NGQDCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQG----LSDMLPTTRGAGMVVDWE 1132
D S+L +A+ D + VW + + E V +G ++ P RG +V
Sbjct: 118 -NTDGSMLFSASTDKTVAVWDS-----ETGERVKRLKGHTSFVNSCYPARRGPQLVC--- 168
Query: 1133 QETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRV 1192
+ D V++WD ++ +Q V +++ + I++G D I+V
Sbjct: 169 -------TGSDDGTVKLWDIRKKAAIQTFQNTYQ--VLAVTFNDTSDQIISGGIDNDIKV 219
Query: 1193 YDRRMALSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFD--PRMPESV--- 1247
+D R T R H V SL +++S +++ VR++D P P+
Sbjct: 220 WDLRQ---NKLTYTMRGHADSVTGLSLSSE-GSYLLSNAMDNTVRVWDVRPFAPKERCVK 275
Query: 1248 ----NVLQIVKGLTALDIHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGA 1303
NV K L P IA GS ++F +++++ I Y + G+
Sbjct: 276 IFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRI----LYK--LPGHAGS 329
Query: 1304 ISCLAFHPHWPHLAVGSND 1322
I+ +AFHP P + S+D
Sbjct: 330 INEVAFHPDEPIIISASSD 348
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 51.2 bits (121), Expect = 6e-06
Identities = 57/226 (25%), Positives = 104/226 (46%), Gaps = 17/226 (7%)
Query: 1110 TAWQGLSDMLPTTRGAGMVVDWEQETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCV 1169
TAW+ L +++ +V + LL + GD V +W ++ + + TG S V
Sbjct: 9 TAWK-LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSL-TGHTSPV 66
Query: 1170 TSLSCDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGHIV- 1228
S+ ++ LIVAG GSIRV+D A +M ++ + SL P G V
Sbjct: 67 ESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANI-----CSLDFHPYGEFVA 121
Query: 1229 SVSVNGDVRIFDPRMPESV-NVLQIVKGLTALDIHPQADLIACGSVNQFTAIYN-SSGEL 1286
S S + +++++D R V + + L P +A + + +++ ++G++
Sbjct: 122 SGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKM 181
Query: 1287 INNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGSNDYYISVYSVEK 1332
++ F G G ++ + FHP+ LA GS+D I + +EK
Sbjct: 182 MSE------FPG-HTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 50.1 bits (118), Expect = 1e-05
Identities = 50/197 (25%), Positives = 83/197 (42%), Gaps = 16/197 (8%)
Query: 1129 VDWEQETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDG 1188
V + LL S+ R VR+W D+ K + + V S+ + + D
Sbjct: 66 VQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHT-APVRSVDFSADGQFLATASEDK 124
Query: 1189 SIRVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGH-IVSVSVNGDVRIFDPRMPESV 1247
SI+V+ M YR HT WV A PDG IVS S + ++I+D + V
Sbjct: 125 SIKVWS--MYRQRFLYSLYR-HTHWVRCAKFS--PDGRLIVSCSEDKTIKIWDTTNKQCV 179
Query: 1248 NVLQIVKGLTA-LDIHPQADLIACGSVNQFTAIYNSS-GELINNIKYYDGFMGQRVGAIS 1305
N G +D +P IA +Q +++ +L+ + + + G ++
Sbjct: 180 NNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSG-------GVN 232
Query: 1306 CLAFHPHWPHLAVGSND 1322
C++FHP +L S+D
Sbjct: 233 CISFHPSGNYLITASSD 249
Score = 32.7 bits (73), Expect = 2.4
Identities = 30/144 (20%), Positives = 62/144 (43%), Gaps = 20/144 (13%)
Query: 1080 DCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLM 1139
D L+++ ++D I++W N + V SD + G VD+ +
Sbjct: 155 DGRLIVSCSEDKTIKIWDT-----TNKQCVN---NFSDSV----GFANFVDFNPSGTCIA 202
Query: 1140 SSGDVRIVRIWD--TDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRM 1197
S+G + V++WD ++ ++ + +G +C+ S + ++ DG++++ D
Sbjct: 203 SAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCI---SFHPSGNYLITASSDGTLKILD--- 256
Query: 1198 ALSECRVMTYREHTAWVVKASLQK 1221
L + T + HT V S K
Sbjct: 257 LLEGRLIYTLQGHTGPVFTVSFSK 280
>gi|148727341 serine/threonine kinase receptor associated protein
[Homo sapiens]
Length = 350
Score = 49.3 bits (116), Expect = 2e-05
Identities = 49/247 (19%), Positives = 103/247 (41%), Gaps = 32/247 (12%)
Query: 1079 QDCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLL 1138
+D + TA D +VW D E++T + VD+ Q++ L
Sbjct: 69 KDATKAATAAADFTAKVW----DAVSGDELMTL---------AHKHIVKTVDFTQDSNYL 115
Query: 1139 MSSGDVRIVRIWDTDR-EMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRM 1197
++ G +++RI+D ++ E + ++I +L C + ++ A D ++R++D
Sbjct: 116 LTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSA--DDKTVRLWD-HA 172
Query: 1198 ALSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLT 1257
++E + + + + +S++ P+G I+ ++ + + + + +
Sbjct: 173 TMTEVKSLNFN-----MSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATIN 227
Query: 1258 ALDIHPQADLIACG--SVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPH 1315
+ +HP+ + + G + YNS EL + Y G G I C+ F P
Sbjct: 228 SASLHPEKEFLVAGGEDFKLYKYDYNSGEEL----ESYKG----HFGPIHCVRFSPDGEL 279
Query: 1316 LAVGSND 1322
A GS D
Sbjct: 280 YASGSED 286
>gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)
[Homo sapiens]
Length = 906
Score = 46.6 bits (109), Expect = 2e-04
Identities = 46/193 (23%), Positives = 80/193 (41%), Gaps = 17/193 (8%)
Query: 1029 VKFHPFTPCIAVADKDSIC-FWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQDCSLLLTA 1087
+ HP P I + D + WDW+K G+ Y +N +D + +A
Sbjct: 105 IAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIV---INPKDNNQFASA 161
Query: 1088 TDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSSGDVRIV 1147
+ D I+VW+ N + +G++ + + G + L+S D R+V
Sbjct: 162 SLDRTIKVWQ-LGSSSPNFTLEGHEKGVNCIDYYSGG---------DKPYLISGADDRLV 211
Query: 1148 RIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTY 1207
+IWD + VQ + A + V+ S +I+ G DG++R++ E + Y
Sbjct: 212 KIWDYQNKTCVQTLEGHAQN-VSCASFHPELPIIITGSEDGTVRIWHSSTYRLE-STLNY 269
Query: 1208 REHTAWVVKASLQ 1220
W V ASL+
Sbjct: 270 GMERVWCV-ASLR 281
>gi|223005862 echinoderm microtubule associated protein like 6 [Homo
sapiens]
Length = 1958
Score = 45.4 bits (106), Expect = 4e-04
Identities = 58/252 (23%), Positives = 103/252 (40%), Gaps = 22/252 (8%)
Query: 1082 SLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSS 1141
+L T +G + VWK+ + + A G + TT G++V +E +
Sbjct: 1567 NLTFTGAINGDVYVWKDHFLIRL---VAKAHTGPVFTMYTTLRDGLIVTGGKER----PT 1619
Query: 1142 GDVRIVRIWDTD-REMKVQDIPTGA-DSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMAL 1199
+ V++WD + + + + TG CV S+ + I+ G DG I + A
Sbjct: 1620 KEGGAVKLWDQEMKRCRAFQLETGQLVECVRSVC--RGKGKILVGTKDGEIIEVGEKNAA 1677
Query: 1200 SECRVMTYREHTAWVVKASLQKRPDGHI-VSVSVNGDVRIFDPRMPESVNVLQIVKGLTA 1258
S + + E W L P + +S S +G RI+D + +N + +
Sbjct: 1678 SNILIDGHMEGEIW----GLATHPSKDLFISASNDGTARIWDLADKKLLNKVSLGHAARC 1733
Query: 1259 LDIHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAV 1318
P +++A G N I L+N++K + G R AI + P LAV
Sbjct: 1734 AAYSPDGEMVAIGMKNGEFVIL-----LVNSLKVW-GKKRDRKSAIQDIRISPDNRFLAV 1787
Query: 1319 GSNDYYISVYSV 1330
GS+++ + Y +
Sbjct: 1788 GSSEHTVDFYDL 1799
Score = 32.3 bits (72), Expect = 3.1
Identities = 70/307 (22%), Positives = 108/307 (35%), Gaps = 57/307 (18%)
Query: 1038 IAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQDCSLLLTATDDGAIRVWK 1097
+ + D SI FWDW+KGEK+ + V N L+T I+ W+
Sbjct: 790 VGLDDFHSIVFWDWKKGEKIATTRGHKDKIFVVKC----NPHHVDKLVT-VGIKHIKFWQ 844
Query: 1098 NFADLEKNPEMVTAWQGLSDMLPTTRGAG-----MVVDWEQETGLLMSSGDVRIVRIWDT 1152
A G + T G M V + + L+ S + IW
Sbjct: 845 Q------------AGGGFTSKRGTFGSVGKLETMMCVSYGRMEDLVFSGAATGDIFIWKD 892
Query: 1153 DREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYD------------RRMALS 1200
+K G + +L V G DG + ++D +R ALS
Sbjct: 893 ILLLKTVKAHDGPVFAMYALD-----KGFVTGGKDGIVELWDDMFERCLKTYAIKRSALS 947
Query: 1201 ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKG-LTAL 1259
E + +L GHI+ + NG++ D P ++ V ++G + L
Sbjct: 948 TSSKGLLLEDNPSIRAITL---GHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGL 1004
Query: 1260 DIHPQADLIACGSVNQFTAIYNSSGE----LINNIKYYDGFMGQRVGAISCLAFHPHWPH 1315
HP + A S ++ I+ S + + +K G R C AF P
Sbjct: 1005 AAHPLLPICATVSDDKTLRIWELSAQHRMLAVRKLK-----KGGR-----CCAFSPDGKA 1054
Query: 1316 LAVGSND 1322
LAVG ND
Sbjct: 1055 LAVGLND 1061
Score = 30.8 bits (68), Expect = 9.1
Identities = 32/147 (21%), Positives = 57/147 (38%), Gaps = 18/147 (12%)
Query: 1083 LLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSSG 1142
L +T +DD ++R+W + AD A +M R D Q L M G
Sbjct: 339 LAVTGSDDRSVRLW-SLAD--------HALIARCNMEEAVRSVAFSPDGSQ-LALGMKDG 388
Query: 1143 DVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVY---DRRMAL 1199
++R+ D + ++D + + S + G DG + VY R +
Sbjct: 389 SFIVLRVRDMTEVVHIKD----RKEVIHEMKFSPDGSYLAVGSNDGPVDVYAVAQRYKKI 444
Query: 1200 SEC-RVMTYREHTAWVVKASLQKRPDG 1225
EC + +++ H W + + + DG
Sbjct: 445 GECSKSLSFITHIDWSLDSKYLQTNDG 471
>gi|34485720 echinoderm microtubule associated protein like 5 [Homo
sapiens]
Length = 1977
Score = 43.5 bits (101), Expect = 0.001
Identities = 58/252 (23%), Positives = 106/252 (42%), Gaps = 22/252 (8%)
Query: 1082 SLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSS 1141
+L T T G + VWK+ + A G + TT G++V +E S
Sbjct: 1582 NLTFTGTISGDVCVWKDHILCRI---VARAHNGPVFAMYTTLRDGLIVTGGKER----PS 1634
Query: 1142 GDVRIVRIWDTD-REMKVQDIPTG-ADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMAL 1199
+ V++WD + R + + TG A CV S+ C ++V I V ++ A
Sbjct: 1635 KEGGAVKLWDQELRRCRAFRLETGQATDCVRSV-CRGKGKILVGTRNAEIIEVGEKNAA- 1692
Query: 1200 SECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTAL 1259
C ++ H + +S + +G VR++D + +N + + +
Sbjct: 1693 --CNILV-NGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTV 1749
Query: 1260 DIHPQADLIACGSVN-QFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAV 1318
P+ D++A G N +F + L++++K + G R AI + F P +LAV
Sbjct: 1750 CYSPEGDMVAIGMKNGEFIIL------LVSSLKIW-GKKRDRRCAIHDIRFSPDSRYLAV 1802
Query: 1319 GSNDYYISVYSV 1330
GS++ + Y +
Sbjct: 1803 GSSENSVDFYDL 1814
Score = 37.4 bits (85), Expect = 0.097
Identities = 74/313 (23%), Positives = 112/313 (35%), Gaps = 69/313 (22%)
Query: 1038 IAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQDCSLLLTA---------- 1087
+ + D ++ WDW+KGEKL + V Y+ + L+TA
Sbjct: 790 VGIDDSHTVVLWDWKKGEKLSIARGSKDKIFVVKMNPYVPDK----LITAGIKHMKFWRK 845
Query: 1088 TDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLL-MSSGDVRI 1146
G I L KN M+ A V W +E S+GDV I
Sbjct: 846 AGGGLIGRKGYIGTLGKNDTMMCA----------------VYGWTEEMAFSGTSTGDVCI 889
Query: 1147 VRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALSECRVMT 1206
R + +K D P S + V G DG + ++D + C + T
Sbjct: 890 WRDIFLVKTVKAHDGPV--------FSMHALEKGFVTGGKDGIVALWDD--SFERC-LKT 938
Query: 1207 YREHTAWVVKAS----LQKRPD--------GHIVSVSVNGDVRIFDPRMPESVNVLQIVK 1254
Y A + S L+ P GHI+ + NG++ D P ++ V ++
Sbjct: 939 YAIKRAALAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHME 998
Query: 1255 G-LTALDIHPQADLIACGSVNQFTAIYNSSGE----LINNIKYYDGFMGQRVGAISCLAF 1309
G + L HP + A S ++ I++ S + +K G R C F
Sbjct: 999 GEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLK-----KGGR-----CCCF 1048
Query: 1310 HPHWPHLAVGSND 1322
P LAVG ND
Sbjct: 1049 SPDGKALAVGLND 1061
>gi|89886480 zinedin isoform 2 [Homo sapiens]
Length = 760
Score = 42.4 bits (98), Expect = 0.003
Identities = 65/291 (22%), Positives = 119/291 (40%), Gaps = 41/291 (14%)
Query: 1067 YTRVTAMEYLNGQDCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLS-DMLP----- 1120
Y + ++ + + Q S LLTA++DG +++W +L+K VTA + + D+ P
Sbjct: 445 YDGIRSLAFHHSQ--SALLTASEDGTLKLW----NLQK---AVTAKKNAALDVEPIHAFR 495
Query: 1121 TTRGAGMVVDWEQETGLLMSSGDVRIVRIWDT-DREMKVQD---------IPTGADSCVT 1170
RG + V + S G + W D M D + G V
Sbjct: 496 AHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGHGDAVW 555
Query: 1171 SLSCDSHRSLIVAGLGDGSIRVYDRRMALSECRVM--TYREHTAWVVKASLQKRPDGHIV 1228
L+ + + DG++R++D + C T EH A P HIV
Sbjct: 556 GLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEP-AHIV 614
Query: 1229 SVSVNGDVRIFDPRMPESVNVLQI--VKGLTALD---IHPQADL-IACGSVNQFTAIYNS 1282
+ +GD ++D + ++ L+ G T ++ HP L I + N
Sbjct: 615 ASFRSGDTVLYDMEVGSALLTLESRGSSGPTQINQVVSHPNQPLTITAHDDRGIRFLDNR 674
Query: 1283 SGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGSNDYYISVYSVEKR 1333
+G+ +++ M + A++CLA P+ L GS+D + ++S++ +
Sbjct: 675 TGKPVHS-------MVAHLDAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNK 718
>gi|89886477 zinedin isoform 1 [Homo sapiens]
Length = 753
Score = 42.4 bits (98), Expect = 0.003
Identities = 65/291 (22%), Positives = 119/291 (40%), Gaps = 41/291 (14%)
Query: 1067 YTRVTAMEYLNGQDCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLS-DMLP----- 1120
Y + ++ + + Q S LLTA++DG +++W +L+K VTA + + D+ P
Sbjct: 438 YDGIRSLAFHHSQ--SALLTASEDGTLKLW----NLQK---AVTAKKNAALDVEPIHAFR 488
Query: 1121 TTRGAGMVVDWEQETGLLMSSGDVRIVRIWDT-DREMKVQD---------IPTGADSCVT 1170
RG + V + S G + W D M D + G V
Sbjct: 489 AHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGHGDAVW 548
Query: 1171 SLSCDSHRSLIVAGLGDGSIRVYDRRMALSECRVM--TYREHTAWVVKASLQKRPDGHIV 1228
L+ + + DG++R++D + C T EH A P HIV
Sbjct: 549 GLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEP-AHIV 607
Query: 1229 SVSVNGDVRIFDPRMPESVNVLQI--VKGLTALD---IHPQADL-IACGSVNQFTAIYNS 1282
+ +GD ++D + ++ L+ G T ++ HP L I + N
Sbjct: 608 ASFRSGDTVLYDMEVGSALLTLESRGSSGPTQINQVVSHPNQPLTITAHDDRGIRFLDNR 667
Query: 1283 SGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGSNDYYISVYSVEKR 1333
+G+ +++ M + A++CLA P+ L GS+D + ++S++ +
Sbjct: 668 TGKPVHS-------MVAHLDAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNK 711
>gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1
[Homo sapiens]
Length = 1129
Score = 42.0 bits (97), Expect = 0.004
Identities = 65/277 (23%), Positives = 117/277 (42%), Gaps = 66/277 (23%)
Query: 1082 SLLLTATDDGAIRVWKNFADLE---------------KNPEMVTAW-----------QGL 1115
S ++T DG +R+W++ D + K+ ++VTA +G+
Sbjct: 26 SFIVTCGSDGDVRIWEDLDDDDPKFINVGEKAYSCALKSGKLVTAVSNNTIQVHTFPEGV 85
Query: 1116 SDMLPT--TRGAGMVVDWEQETGLLMSSGD--VRIVRIWDTDREMKVQDIPTGADSCVTS 1171
D + T T A VV T + S D V+IV + D+ ++ + G D+ V S
Sbjct: 86 PDGILTRFTTNANHVVFNGDGTKIAAGSSDFLVKIVDVMDSSQQKTFR----GHDAPVLS 141
Query: 1172 LSCDSHRSLIVAGLGDGSIRVY---DRRMALS-----ECRVMTYRE---HTAWVVKASLQ 1220
LS D + + DGS+RV+ D+ A+S +C + + AW K+
Sbjct: 142 LSFDPKDIFLASASCDGSVRVWQISDQTCAISWPLLQKCNDVINAKSICRLAWQPKS--- 198
Query: 1221 KRPDGHIVSVSVNGDVRIF-----DPRMPESVNVLQIVKGLTALDIHPQADLIACGSVNQ 1275
G ++++ V V+++ + S N I + L + P +A GS+N
Sbjct: 199 ----GKLLAIPVEKSVKLYRRESWSHQFDLSDNF--ISQTLNIVTWSPCGQYLAAGSING 252
Query: 1276 FTAIYN-SSGELINNIKYYDGFMGQRVGAISCLAFHP 1311
++N + + + +K+ G+ AI LA+HP
Sbjct: 253 LIIVWNVETKDCMERVKHEKGY------AICGLAWHP 283
>gi|50980309 UTP15, U3 small nucleolar ribonucleoprotein, homolog
[Homo sapiens]
Length = 518
Score = 41.2 bits (95), Expect = 0.007
Identities = 38/201 (18%), Positives = 92/201 (45%), Gaps = 14/201 (6%)
Query: 1131 WEQETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSI 1190
+ Q+ LL++ + V+++D ++ G V ++ + + +V+G D ++
Sbjct: 88 FRQDGRLLVAGSEDGGVQLFDISGRAPLRQFE-GHTKAVHTVDFTADKYHVVSGADDYTV 146
Query: 1191 RVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVL 1250
+++D + ++T++EH+ +V K ++ S + V++FD R ESV +
Sbjct: 147 KLWD---IPNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSESVLSV 203
Query: 1251 QIVKGLTALDIHPQADLIACGSVNQFTAIYN--SSGELINNIKYYDGFMGQRVGAISCLA 1308
+ + + ++ + P L+ ++ +++ G+L+ ++K + ++CL
Sbjct: 204 EHGQPVESVLLFPSGGLLVSAG-GRYVKVWDMLKGGQLLVSLKNHH-------KTVTCLC 255
Query: 1309 FHPHWPHLAVGSNDYYISVYS 1329
L GS D + VYS
Sbjct: 256 LSSSGQRLLSGSLDRKVKVYS 276
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 40.8 bits (94), Expect = 0.009
Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 1129 VDWEQETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDG 1188
V W ++ LL+S+ D + ++IWD ++ + G + V + + +LIV+G D
Sbjct: 93 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDE 151
Query: 1189 SIRVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVN 1248
S+R++D + +C + T H+ V A R IVS S +G RI+D + +
Sbjct: 152 SVRIWD--VKTGKC-LKTLPAHSD-PVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLK 207
Query: 1249 VL 1250
L
Sbjct: 208 TL 209
Score = 37.7 bits (86), Expect = 0.074
Identities = 29/115 (25%), Positives = 58/115 (50%), Gaps = 13/115 (11%)
Query: 1080 DCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLM 1139
D +LL++A+DD +++W D+ + T +G S+ + ++ ++ L++
Sbjct: 98 DSNLLVSASDDKTLKIW----DVSSGKCLKTL-KGHSNYV-------FCCNFNPQSNLIV 145
Query: 1140 SSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYD 1194
S VRIWD ++ +P +D V+++ + SLIV+ DG R++D
Sbjct: 146 SGSFDESVRIWDVKTGKCLKTLPAHSDP-VSAVHFNRDGSLIVSSSYDGLCRIWD 199
Score = 34.7 bits (78), Expect = 0.63
Identities = 49/241 (20%), Positives = 103/241 (42%), Gaps = 27/241 (11%)
Query: 1038 IAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQDCSLLLTATDDGAIRVWK 1097
++ +D ++ WD G+ L G+ Y +L+++ + D ++R+W
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFN----PQSNLIVSGSFDESVRIW- 156
Query: 1098 NFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSSGDVRIVRIWDTDREMK 1157
D++ + T LP V + ++ L++SS + RIWDT
Sbjct: 157 ---DVKTGKCLKT--------LPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQC 205
Query: 1158 VQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALSEC-RVMTYREHTAWVVK 1216
++ + + V+ + + I+A D +++++D + +C + T ++ + +
Sbjct: 206 LKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD--YSKGKCLKTYTGHKNEKYCIF 263
Query: 1217 ASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALDI----HPQADLIACGS 1272
A+ IVS S + V I++ + E V LQ G T + I HP ++IA +
Sbjct: 264 ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ---GHTDVVISTACHPTENIIASAA 320
Query: 1273 V 1273
+
Sbjct: 321 L 321
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 40.8 bits (94), Expect = 0.009
Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 1129 VDWEQETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDG 1188
V W ++ LL+S+ D + ++IWD ++ + G + V + + +LIV+G D
Sbjct: 93 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDE 151
Query: 1189 SIRVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVN 1248
S+R++D + +C + T H+ V A R IVS S +G RI+D + +
Sbjct: 152 SVRIWD--VKTGKC-LKTLPAHSD-PVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLK 207
Query: 1249 VL 1250
L
Sbjct: 208 TL 209
Score = 37.7 bits (86), Expect = 0.074
Identities = 29/115 (25%), Positives = 58/115 (50%), Gaps = 13/115 (11%)
Query: 1080 DCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLM 1139
D +LL++A+DD +++W D+ + T +G S+ + ++ ++ L++
Sbjct: 98 DSNLLVSASDDKTLKIW----DVSSGKCLKTL-KGHSNYV-------FCCNFNPQSNLIV 145
Query: 1140 SSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYD 1194
S VRIWD ++ +P +D V+++ + SLIV+ DG R++D
Sbjct: 146 SGSFDESVRIWDVKTGKCLKTLPAHSDP-VSAVHFNRDGSLIVSSSYDGLCRIWD 199
Score = 34.7 bits (78), Expect = 0.63
Identities = 49/241 (20%), Positives = 103/241 (42%), Gaps = 27/241 (11%)
Query: 1038 IAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQDCSLLLTATDDGAIRVWK 1097
++ +D ++ WD G+ L G+ Y +L+++ + D ++R+W
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFN----PQSNLIVSGSFDESVRIW- 156
Query: 1098 NFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSSGDVRIVRIWDTDREMK 1157
D++ + T LP V + ++ L++SS + RIWDT
Sbjct: 157 ---DVKTGKCLKT--------LPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQC 205
Query: 1158 VQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALSEC-RVMTYREHTAWVVK 1216
++ + + V+ + + I+A D +++++D + +C + T ++ + +
Sbjct: 206 LKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD--YSKGKCLKTYTGHKNEKYCIF 263
Query: 1217 ASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALDI----HPQADLIACGS 1272
A+ IVS S + V I++ + E V LQ G T + I HP ++IA +
Sbjct: 264 ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ---GHTDVVISTACHPTENIIASAA 320
Query: 1273 V 1273
+
Sbjct: 321 L 321
>gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo
sapiens]
Length = 504
Score = 40.8 bits (94), Expect = 0.009
Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 11/162 (6%)
Query: 1174 CDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVN 1233
C S + I+ G D ++ V+D+ SE + T + HT V D + S S +
Sbjct: 230 CPSDTNKILTGGADKNVVVFDKS---SEQILATLKGHTKKVTSVVFHPSQD-LVFSASPD 285
Query: 1234 GDVRIFDPRMPESVNVLQIVKG-LTALDIHPQADLIACGSVNQFTAIYN-SSGELINNIK 1291
+RI+ V V++ + +T L +H D + S +Q+ A + +G ++ +
Sbjct: 286 ATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVT 345
Query: 1292 YYDGFMGQRVGAISCLAFHPHWPHLAVGSNDYYISVYSVEKR 1333
D G +++C FHP G+ D I ++ +++R
Sbjct: 346 --DETSGC---SLTCAQFHPDGLIFGTGTMDSQIKIWDLKER 382
>gi|124256480 APG16 autophagy 16-like isoform 1 [Homo sapiens]
Length = 607
Score = 40.4 bits (93), Expect = 0.011
Identities = 56/264 (21%), Positives = 117/264 (44%), Gaps = 28/264 (10%)
Query: 1070 VTAMEYLNGQDCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMV- 1128
V A+++ G LL T D +++W+ F + E + G + AG+
Sbjct: 325 VNAVQFSPGS--RLLATGGMDRRVKLWEVFGE---KCEFKGSLSGSN--------AGITS 371
Query: 1129 VDWEQETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDG 1188
++++ L+++ + RIW D + +++ TG V S + IV+G D
Sbjct: 372 IEFDSAGSYLLAASNDFASRIWTVD-DYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDR 430
Query: 1189 SIRVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVN 1248
+++++D R + C + + + + Q GH + +R +D R V
Sbjct: 431 TLKLWDLRSKV--CIKTVFAGSSCNDIVCTEQCVMSGHF-----DKKIRFWDIRSESIVR 483
Query: 1249 VLQIVKGLTALDIHPQ-ADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGA-ISC 1306
++++ +TALD++P+ +L++C + I + N IK G + G+ +
Sbjct: 484 EMELLGKITALDLNPERTELLSCSRDDLLKVIDLRT----NAIKQTFSAPGFKCGSDWTR 539
Query: 1307 LAFHPHWPHLAVGSNDYYISVYSV 1330
+ F P ++A GS + + ++SV
Sbjct: 540 VVFSPDGSYVAAGSAEGSLYIWSV 563
>gi|124256478 APG16 autophagy 16-like isoform 2 [Homo sapiens]
Length = 588
Score = 40.4 bits (93), Expect = 0.011
Identities = 56/264 (21%), Positives = 117/264 (44%), Gaps = 28/264 (10%)
Query: 1070 VTAMEYLNGQDCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMV- 1128
V A+++ G LL T D +++W+ F + E + G + AG+
Sbjct: 306 VNAVQFSPGS--RLLATGGMDRRVKLWEVFGE---KCEFKGSLSGSN--------AGITS 352
Query: 1129 VDWEQETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDG 1188
++++ L+++ + RIW D + +++ TG V S + IV+G D
Sbjct: 353 IEFDSAGSYLLAASNDFASRIWTVD-DYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDR 411
Query: 1189 SIRVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVN 1248
+++++D R + C + + + + Q GH + +R +D R V
Sbjct: 412 TLKLWDLRSKV--CIKTVFAGSSCNDIVCTEQCVMSGHF-----DKKIRFWDIRSESIVR 464
Query: 1249 VLQIVKGLTALDIHPQ-ADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGA-ISC 1306
++++ +TALD++P+ +L++C + I + N IK G + G+ +
Sbjct: 465 EMELLGKITALDLNPERTELLSCSRDDLLKVIDLRT----NAIKQTFSAPGFKCGSDWTR 520
Query: 1307 LAFHPHWPHLAVGSNDYYISVYSV 1330
+ F P ++A GS + + ++SV
Sbjct: 521 VVFSPDGSYVAAGSAEGSLYIWSV 544
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 40.0 bits (92), Expect = 0.015
Identities = 55/263 (20%), Positives = 104/263 (39%), Gaps = 32/263 (12%)
Query: 1081 CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDM---LPTTRGAGMVVDWEQETGL 1137
C +L T +DG I++W+ L ++ G D+ L T ++
Sbjct: 123 CLVLATGLNDGQIKIWEVQTGL-----LLLNLSGHQDVVRDLSFTPSGSLI--------- 168
Query: 1138 LMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRM 1197
L+S+ + +RIWD ++ K + +G V S S++ + G+ S+ ++ R
Sbjct: 169 LVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMR- 227
Query: 1198 ALSECRVMTYREHTAWVVKASLQKRPDGH-IVSVSVNGDVRIFDPRMPE---SVNVLQIV 1253
S + H + VV PD +V+ S + +V ++DP E S++ Q+
Sbjct: 228 --SYTLIRKLEGHQSSVVSCDFS--PDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVD 283
Query: 1254 KGLTALDIHPQADLIACGSVNQFTAIYNSSGELIN----NIKYYDGFMGQRVGAISCLAF 1309
+ D+H + C S + L+ +K F G C F
Sbjct: 284 PAMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNGL--CCTF 341
Query: 1310 HPHWPHLAVGSNDYYISVYSVEK 1332
PH +A G+ D ++ ++ +
Sbjct: 342 FPHGGVIATGTRDGHVQFWTAPR 364
>gi|148536855 coatomer protein complex, subunit alpha isoform 1 [Homo
sapiens]
Length = 1233
Score = 39.3 bits (90), Expect = 0.026
Identities = 60/279 (21%), Positives = 107/279 (38%), Gaps = 50/279 (17%)
Query: 1084 LLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSSGD 1143
+LT+ +G I++W + M T L D G +D+ ++ L +S GD
Sbjct: 24 ILTSLHNGVIQLW--------DYRMCT----LIDKFDEHDGPVRGIDFHKQQPLFVSGGD 71
Query: 1144 VRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALSECR 1203
+++W+ + + D T+ + ++ A D +IRV++ + C
Sbjct: 72 DYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSAS-DDQTIRVWNWQSRTCVC- 129
Query: 1204 VMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVN-----VLQIVKGLTA 1258
V+T H +V+ A D +VS S++ VR++D N V V+G+T
Sbjct: 130 VLTGHNH--YVMCAQFHPTED-LVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITG 186
Query: 1259 LDI------------------------HPQADLIACGSVNQFTAIYNSSGELINNIKYYD 1294
+D+ HP LI G+ ++ I+ + +
Sbjct: 187 VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCR 246
Query: 1295 GFMGQRVGAISCLAFHPHWPHLAVGSNDYYISVYSVEKR 1333
G +SC FHP + S D I V+ + KR
Sbjct: 247 GHYNN----VSCAVFHPRQELILSNSEDKSIRVWDMSKR 281
>gi|148536853 coatomer protein complex, subunit alpha isoform 2 [Homo
sapiens]
Length = 1224
Score = 39.3 bits (90), Expect = 0.026
Identities = 60/279 (21%), Positives = 107/279 (38%), Gaps = 50/279 (17%)
Query: 1084 LLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSSGD 1143
+LT+ +G I++W + M T L D G +D+ ++ L +S GD
Sbjct: 24 ILTSLHNGVIQLW--------DYRMCT----LIDKFDEHDGPVRGIDFHKQQPLFVSGGD 71
Query: 1144 VRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALSECR 1203
+++W+ + + D T+ + ++ A D +IRV++ + C
Sbjct: 72 DYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSAS-DDQTIRVWNWQSRTCVC- 129
Query: 1204 VMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVN-----VLQIVKGLTA 1258
V+T H +V+ A D +VS S++ VR++D N V V+G+T
Sbjct: 130 VLTGHNH--YVMCAQFHPTED-LVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITG 186
Query: 1259 LDI------------------------HPQADLIACGSVNQFTAIYNSSGELINNIKYYD 1294
+D+ HP LI G+ ++ I+ + +
Sbjct: 187 VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCR 246
Query: 1295 GFMGQRVGAISCLAFHPHWPHLAVGSNDYYISVYSVEKR 1333
G +SC FHP + S D I V+ + KR
Sbjct: 247 GHYNN----VSCAVFHPRQELILSNSEDKSIRVWDMSKR 281
>gi|157502169 astacin-like metalloendopeptidase [Homo sapiens]
Length = 431
Score = 39.3 bits (90), Expect = 0.026
Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 849 RVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRDLPSGRP-- 906
RVL + S P P +G H H G SP +S S L ++ + S D PSG
Sbjct: 274 RVLKLYGCSPSGPR-PRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPD-PSGSSAG 331
Query: 907 GTTGPAGAQYTPHSHQFPRTRKM 929
G PAG +PH + P +K+
Sbjct: 332 GQPVPAGPGESPHGWESPALKKL 354
>gi|221219004 WD repeat domain 74 [Homo sapiens]
Length = 385
Score = 38.9 bits (89), Expect = 0.033
Identities = 48/223 (21%), Positives = 91/223 (40%), Gaps = 24/223 (10%)
Query: 1124 GAGMVVDWEQETGLLMSSGDVRIVRIW-DTDREMK---VQDIPTGADSCVTSLSCDSHRS 1179
G GM Q G L++ D I+R+W D D++ + ++ G C +H
Sbjct: 86 GEGMFRGLAQADGTLITCVDSGILRVWHDKDKDTSSDPLLELRVGPGVC-RMRQDPAHPH 144
Query: 1180 LIVAGLGDGSIRVYDRRMALSECRVMTYREHTAW------VVKASLQKRPDGH-IVSVSV 1232
++ G + +++++D + E W + +Q P +V+ +
Sbjct: 145 VVATGGKENALKIWDLQ-GSEEPVFRAKNVRNDWLDLRVPIWDQDIQFLPGSQKLVTCTG 203
Query: 1233 NGDVRIFDPRMPESVNVLQIVKG---LTALDIHPQADLIACGSVN-QFTAIYNSSGELIN 1288
VR++DP P+ VL+ G LTA+ + P + + G+ + Q I G L+
Sbjct: 204 YHQVRVYDPASPQRRPVLETTYGEYPLTAMTLTPGGNSVIVGNTHGQLAEIDLRQGRLL- 262
Query: 1289 NIKYYDGFMGQRVGAISCLAFHPHWPHLAVGSNDYYISVYSVE 1331
G + G++ L HP P LA D + ++ ++
Sbjct: 263 ------GCLKGLAGSVRGLQCHPSKPLLASCGLDRVLRIHRIQ 299
>gi|13129110 WD repeat domain 77 [Homo sapiens]
Length = 342
Score = 38.9 bits (89), Expect = 0.033
Identities = 61/258 (23%), Positives = 109/258 (42%), Gaps = 24/258 (9%)
Query: 1080 DCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLM 1139
D +LLL A+ R W L K+P +G T + W E G+L+
Sbjct: 39 DGALLLGASSLSG-RCWAGSLWLFKDP-CAAPNEGFCSAGVQTEAGVADLTWVGERGILV 96
Query: 1140 SSGDVRIVRIWDTDREMKV---QDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRR 1196
+S D V +W+ D + + D V+++S S + V+G D I+V+D
Sbjct: 97 AS-DSGAVELWELDENETLIVSKFCKYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWD-- 153
Query: 1197 MALSECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQI-VKG 1255
+ + +YR H A V + D +S S + + ++D R P+ + + G
Sbjct: 154 -LAQQVVLSSYRAHAAQVTCVAASPHKDSVFLSCSEDNRILLWDTRCPKPASQIGCSAPG 212
Query: 1256 L--TALDIHP-QADLIACGSVNQFTAIYN--SSGELINNIKYYDGFMGQRVGAISCLAFH 1310
T+L HP Q+++ G N ++ + S+ ++++ + ++ L F
Sbjct: 213 YLPTSLAWHPQQSEVFVFGDENGTVSLVDTKSTSCVLSSAVHSQ--------CVTGLVFS 264
Query: 1311 PH-WPHLAVGSNDYYISV 1327
PH P LA S D ++V
Sbjct: 265 PHSVPFLASLSEDCSLAV 282
>gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
Length = 676
Score = 37.7 bits (86), Expect = 0.074
Identities = 39/181 (21%), Positives = 77/181 (42%), Gaps = 18/181 (9%)
Query: 1114 GLSDMLPTTRGAGMVVDWEQETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLS 1173
GL L G ++W ++ LL S D + +WD K+ + TG + + S+
Sbjct: 38 GLEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVK 97
Query: 1174 CDSHRS--LIVAGLGDGSIRVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGHIVSVS 1231
H +++ G D + V+D + + E + + +HT V + + S +
Sbjct: 98 FLPHAGDRILITGAADSKVHVHD--LTVKE-TIHMFGDHTNRVKRIATAPMWPNTFWSAA 154
Query: 1232 VNGDVRIFDPRMPESVNVLQIVKGLT----------ALDIHPQ-ADLIACGSVNQFTAIY 1280
+G +R +D R E+ +++ LT L ++PQ + +A G+ F +Y
Sbjct: 155 EDGLIRQYDLR--ENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFVRLY 212
Query: 1281 N 1281
+
Sbjct: 213 D 213
>gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [Homo
sapiens]
Length = 340
Score = 37.7 bits (86), Expect = 0.074
Identities = 65/306 (21%), Positives = 118/306 (38%), Gaps = 67/306 (21%)
Query: 1069 RVTAMEYLNGQDCSLLLTATDDGAIRVWKNFAD-------LEKNPEMVTAWQ-------- 1113
++ AM + G D LL++A+ DG + +W ++ L + M A+
Sbjct: 57 KIYAMHW--GYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVAC 114
Query: 1114 -GLSDM------------------LPTTRGAGMVVDWEQETGLLMSSGDVRIVRIWDTDR 1154
GL ++ LP G + ++ ++ SSGD +WD +
Sbjct: 115 GGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCA-LWDIET 173
Query: 1155 EMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHTAWV 1214
+ TG V SLS V+G D S +++D R + CR ++ H + +
Sbjct: 174 AQQTTTF-TGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGM--CR-QSFTGHVSDI 229
Query: 1215 VKASLQKRPDGHIVSV-SVNGDVRIFDPRMPESVNVL---QIVKGLTALDIHPQADLIAC 1270
S P+G+ + S + R+FD R + + + I+ G+T++ L+
Sbjct: 230 NAVSF--FPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLA 287
Query: 1271 GSVNQFTAIYNSSGELINNIKYYDGFMGQRVGA-------ISCLAFHPHWPHLAVGSNDY 1323
G + F N +D G R G +SCL +A GS D
Sbjct: 288 G-YDDF------------NCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDS 334
Query: 1324 YISVYS 1329
++ +++
Sbjct: 335 FLRIWN 340
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 37.0 bits (84), Expect = 0.13
Identities = 44/202 (21%), Positives = 86/202 (42%), Gaps = 16/202 (7%)
Query: 1129 VDWEQETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDG 1188
V++ LL S + VRIW + + + + + C +S + A D
Sbjct: 29 VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTAS-DDK 87
Query: 1189 SIRVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGH-IVSVSVNGDVRIFDPRMPESV 1247
+++V+ + + + +H WV A PDG IVS S + V+++D E V
Sbjct: 88 TVKVWATHR---QKFLFSLSQHINWVRCAKFS--PDGRLIVSASDDKTVKLWDKSSRECV 142
Query: 1248 NVLQIVKG-LTALDIHPQADLIACGSVNQFTAIYN-SSGELINNIKYYDGFMGQRVGAIS 1305
+ G +T +D HP IA ++ +++ + L+ + + + A++
Sbjct: 143 HSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSA-------AVN 195
Query: 1306 CLAFHPHWPHLAVGSNDYYISV 1327
L+FHP +L S+D + +
Sbjct: 196 GLSFHPSGNYLITASSDSTLKI 217
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 37.0 bits (84), Expect = 0.13
Identities = 44/202 (21%), Positives = 86/202 (42%), Gaps = 16/202 (7%)
Query: 1129 VDWEQETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDG 1188
V++ LL S + VRIW + + + + + C +S + A D
Sbjct: 67 VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTAS-DDK 125
Query: 1189 SIRVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGH-IVSVSVNGDVRIFDPRMPESV 1247
+++V+ + + + +H WV A PDG IVS S + V+++D E V
Sbjct: 126 TVKVWATHR---QKFLFSLSQHINWVRCAKFS--PDGRLIVSASDDKTVKLWDKSSRECV 180
Query: 1248 NVLQIVKG-LTALDIHPQADLIACGSVNQFTAIYN-SSGELINNIKYYDGFMGQRVGAIS 1305
+ G +T +D HP IA ++ +++ + L+ + + + A++
Sbjct: 181 HSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSA-------AVN 233
Query: 1306 CLAFHPHWPHLAVGSNDYYISV 1327
L+FHP +L S+D + +
Sbjct: 234 GLSFHPSGNYLITASSDSTLKI 255
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 37.0 bits (84), Expect = 0.13
Identities = 44/202 (21%), Positives = 86/202 (42%), Gaps = 16/202 (7%)
Query: 1129 VDWEQETGLLMSSGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDG 1188
V++ LL S + VRIW + + + + + C +S + A D
Sbjct: 67 VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTAS-DDK 125
Query: 1189 SIRVYDRRMALSECRVMTYREHTAWVVKASLQKRPDGH-IVSVSVNGDVRIFDPRMPESV 1247
+++V+ + + + +H WV A PDG IVS S + V+++D E V
Sbjct: 126 TVKVWATHR---QKFLFSLSQHINWVRCAKFS--PDGRLIVSASDDKTVKLWDKSSRECV 180
Query: 1248 NVLQIVKG-LTALDIHPQADLIACGSVNQFTAIYN-SSGELINNIKYYDGFMGQRVGAIS 1305
+ G +T +D HP IA ++ +++ + L+ + + + A++
Sbjct: 181 HSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSA-------AVN 233
Query: 1306 CLAFHPHWPHLAVGSNDYYISV 1327
L+FHP +L S+D + +
Sbjct: 234 GLSFHPSGNYLITASSDSTLKI 255
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 37.0 bits (84), Expect = 0.13
Identities = 58/263 (22%), Positives = 91/263 (34%), Gaps = 24/263 (9%)
Query: 693 ALPSPATTEGGSLTPVRDSPCTPRLRSVSSYGNIRAVATARSLN-KSLQNLSLTEESGGA 751
A P TT G S P S SS G+ A + S SL S T S
Sbjct: 4122 AFPDSTTTSGLSQEPTT---------SHSSQGSTEATLSPGSTTASSLGQQSTTFHS--- 4169
Query: 752 VAFSPGNLSTSSSASSTLGSPENEEHILSFETIDKMRRASSYSSLNSLIGVSFNSVYTQI 811
SPG+ T+ T+ S E + + + + +S S G+ S Q
Sbjct: 4170 ---SPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTST-GLQEESTTFQS 4225
Query: 812 WRVLLHLAADPYPEVSDVAMKVLNSIAYKATVNARPQRVLDTSSLTQSAPASPTNKGVHI 871
W P P + V ++V T ++RP T S + + +
Sbjct: 4226 WPSSSDTTPSP-PSTTAVPVEV------STTYHSRPSSTPTTHFSASSTTLGRSEESTTV 4278
Query: 872 HQAGGSPPASSTSSSSLTNDVAKQPVSRDLPSGRPGTTGPAGAQYTPHSHQFPRTRKMFD 931
H + G+ + + S T+ + +P + + SG TT G+ T + T
Sbjct: 4279 HSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSP 4338
Query: 932 KGPEQTADDADDAAGHKSFISAT 954
+ P+ T A + S S T
Sbjct: 4339 RSPDTTLSPASTTSSGVSEESTT 4361
Score = 34.7 bits (78), Expect = 0.63
Identities = 57/263 (21%), Positives = 90/263 (34%), Gaps = 24/263 (9%)
Query: 693 ALPSPATTEGGSLTPVRDSPCTPRLRSVSSYGNIRAVATARSLN-KSLQNLSLTEESGGA 751
A P TT G S P S SS G+ A + S SL S T S
Sbjct: 3039 AFPDSTTTSGLSQEPTA---------SHSSQGSTEATLSPGSTTASSLGQQSTTFHS--- 3086
Query: 752 VAFSPGNLSTSSSASSTLGSPENEEHILSFETIDKMRRASSYSSLNSLIGVSFNSVYTQI 811
SPG+ T+ T+ S E + + + + +S S G+ S Q
Sbjct: 3087 ---SPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSA-GLQEESTTFQS 3142
Query: 812 WRVLLHLAADPYPEVSDVAMKVLNSIAYKATVNARPQRVLDTSSLTQSAPASPTNKGVHI 871
W P P + ++V T ++RP T S + + +
Sbjct: 3143 WPSSSDTTPSP-PGTTAAPVEV------STTYHSRPSSTPTTHFSASSTTLGRSEESTTV 3195
Query: 872 HQAGGSPPASSTSSSSLTNDVAKQPVSRDLPSGRPGTTGPAGAQYTPHSHQFPRTRKMFD 931
H + G+ + + S T+ + +P + + SG TT G+ T + T
Sbjct: 3196 HSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSP 3255
Query: 932 KGPEQTADDADDAAGHKSFISAT 954
+ P+ T A + S S T
Sbjct: 3256 RSPDTTLSPASTTSSGVSEESTT 3278
Score = 34.3 bits (77), Expect = 0.82
Identities = 51/269 (18%), Positives = 92/269 (34%), Gaps = 11/269 (4%)
Query: 686 IEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSVSSYGNIRAVATARSLNKSLQNLSLT 745
+ EE + + P +T T DS T L + + +T +L+ S
Sbjct: 1464 VSEESSTSHSQPGSTH---TTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSL 1520
Query: 746 EESGGAVAFSPGNLSTSSSASSTLGSPENEEHILSFETIDKMRRASSYSSLNSLIGVSFN 805
+ SPG+ T+ T+ S E + + + + +S S G+
Sbjct: 1521 GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSA-GLQEE 1579
Query: 806 SVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYKATVNARPQRVLDTSSLTQSAPASPT 865
S Q W P P + ++V T ++RP T S +
Sbjct: 1580 STTFQSWPSSSDTTPSP-PGTTAAPVEV------STTYHSRPSSTPTTHFSASSTTLGRS 1632
Query: 866 NKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRDLPSGRPGTTGPAGAQYTPHSHQFPR 925
+ +H + G+ + + S T+ + +P + + SG TT G+ T +
Sbjct: 1633 EESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKST 1692
Query: 926 TRKMFDKGPEQTADDADDAAGHKSFISAT 954
T + P+ T A + S S T
Sbjct: 1693 TFYSSPRSPDTTLSPASTTSSGVSEESTT 1721
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,119,507
Number of Sequences: 37866
Number of extensions: 2414638
Number of successful extensions: 8569
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 8277
Number of HSP's gapped (non-prelim): 388
length of query: 1335
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1221
effective length of database: 13,930,794
effective search space: 17009499474
effective search space used: 17009499474
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.