Search of human proteins with 22035629

Search of human proteins with 22035629

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22035629 leukotriene C4 synthase [Homo sapiens]
         (150 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22035629 leukotriene C4 synthase [Homo sapiens]                    295   1e-80
gi|4505181 microsomal glutathione S-transferase 2 [Homo sapiens]      124   2e-29
gi|15718675 arachidonate 5-lipoxygenase-activating protein [Homo...    78   3e-15
gi|21717816 solute carrier family 15, member 4 [Homo sapiens]          31   0.34 
gi|226442744 hypothetical protein LOC643965 [Homo sapiens]             29   1.3  
gi|239741003 PREDICTED: hypothetical protein LOC643965 [Homo sap...    29   1.3  
gi|169173314 PREDICTED: hypothetical protein LOC286177 [Homo sap...    28   2.2  
gi|24308167 SV2 related protein [Homo sapiens]                         28   2.9  
gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens]       28   3.8  
gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo...    27   5.0  
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi...    27   6.5  
gi|134304856 solute carrier family 6, member 7 [Homo sapiens]          27   6.5  
gi|169201839 PREDICTED: similar to hCG2038970 [Homo sapiens]           27   8.5  
gi|169201482 PREDICTED: similar to hCG2038970 [Homo sapiens]           27   8.5  
gi|239744229 PREDICTED: similar to hCG2038970 [Homo sapiens]           27   8.5  
gi|13236579 solute carrier family 27 member 3 [Homo sapiens]           27   8.5  

>gi|22035629 leukotriene C4 synthase [Homo sapiens]
          Length = 150

 Score =  295 bits (754), Expect = 1e-80
 Identities = 150/150 (100%), Positives = 150/150 (100%)

Query: 1   MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF 60
           MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
Sbjct: 1   MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF 60

Query: 61  PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA 120
           PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
Sbjct: 61  PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA 120

Query: 121 LAALGLLAHFLPAALRAALLGRLRTLLPWA 150
           LAALGLLAHFLPAALRAALLGRLRTLLPWA
Sbjct: 121 LAALGLLAHFLPAALRAALLGRLRTLLPWA 150


>gi|4505181 microsomal glutathione S-transferase 2 [Homo sapiens]
          Length = 147

 Score =  124 bits (312), Expect = 2e-29
 Identities = 64/138 (46%), Positives = 89/138 (64%)

Query: 7   LLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLAT 66
           LLAAV++L    Q+YF+LQV  AR  ++V+PP  TG PEFERV+RAQ NC E++P+F+ T
Sbjct: 7   LLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNCVEFYPIFIIT 66

Query: 67  LWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGL 126
           LW+AG +F++  A   GLVY++ R  YF GY+ +A+ R+     S   L LL  L ALG+
Sbjct: 67  LWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILALLTLLGALGI 126

Query: 127 LAHFLPAALRAALLGRLR 144
              FL   L   +  +LR
Sbjct: 127 ANSFLDEYLDLNIAKKLR 144


>gi|15718675 arachidonate 5-lipoxygenase-activating protein [Homo
           sapiens]
          Length = 161

 Score = 77.8 bits (190), Expect = 3e-15
 Identities = 45/127 (35%), Positives = 62/127 (48%)

Query: 5   VALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFL 64
           V LLA VTL+ V+   +F+ +V    R         TG   FERVY A  NC + +P FL
Sbjct: 9   VVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNCVDAYPTFL 68

Query: 65  ATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAAL 124
           A LW AG+   +  AA  GL+YLF R +YF GY               R +  L  ++  
Sbjct: 69  AVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSVA 128

Query: 125 GLLAHFL 131
           G+  ++L
Sbjct: 129 GIFNYYL 135


>gi|21717816 solute carrier family 15, member 4 [Homo sapiens]
          Length = 577

 Score = 31.2 bits (69), Expect = 0.34
 Identities = 34/80 (42%), Positives = 40/80 (50%), Gaps = 13/80 (16%)

Query: 73  FFHEGAAALCGLVYLFARLRY----FQGYARSAQLRLAPLYASARALWLLVALAALGLLA 128
           F  EGA A   L+ LF  L Y    F G+   A+L        ARA+ L +AL  LG+LA
Sbjct: 67  FCWEGAQASEALL-LFMGLTYLGSPFGGWLADARL------GRARAILLSLALYLLGMLA 119

Query: 129 HFLPA--ALRAALLGRLRTL 146
             L A  A RAAL G  R L
Sbjct: 120 FPLLAAPATRAALCGSARLL 139


>gi|226442744 hypothetical protein LOC643965 [Homo sapiens]
          Length = 163

 Score = 29.3 bits (64), Expect = 1.3
 Identities = 40/124 (32%), Positives = 57/124 (45%), Gaps = 17/124 (13%)

Query: 36  SPPLTTGPPEFERVYRAQVNCSEYF-PLFLATLWVAGIFFH---EGAAALCGLVYLFARL 91
           +P L  GPP+ +    + + C  +  P  L    +AG+  H     AA L  LV L A  
Sbjct: 21  APMLPRGPPDHQA---SALTCPGWSGPPLLPGRLLAGLLLHLLLPAAAFL--LVLLPAAA 75

Query: 92  RYFQGYARSAQLRLAPLYASARALWL---LVALAALGLLAH----FLPAALRAALLGRLR 144
             + G+   +++  AP     RAL+      AL   GLL+      L +A+RA L  RLR
Sbjct: 76  VVYLGFLCHSRVHPAP-GPRCRALFSDRGSAALIVFGLLSLPPLLVLASAVRARLARRLR 134

Query: 145 TLLP 148
            LLP
Sbjct: 135 PLLP 138


>gi|239741003 PREDICTED: hypothetical protein LOC643965 [Homo
           sapiens]
          Length = 487

 Score = 29.3 bits (64), Expect = 1.3
 Identities = 40/124 (32%), Positives = 57/124 (45%), Gaps = 17/124 (13%)

Query: 36  SPPLTTGPPEFERVYRAQVNCSEYF-PLFLATLWVAGIFFH---EGAAALCGLVYLFARL 91
           +P L  GPP+ +    + + C  +  P  L    +AG+  H     AA L  LV L A  
Sbjct: 345 APMLPRGPPDHQA---SALTCPGWSGPPLLPGRLLAGLLLHLLLPAAAFL--LVLLPAAA 399

Query: 92  RYFQGYARSAQLRLAPLYASARALWL---LVALAALGLLAH----FLPAALRAALLGRLR 144
             + G+   +++  AP     RAL+      AL   GLL+      L +A+RA L  RLR
Sbjct: 400 VVYLGFLCHSRVHPAP-GPRCRALFSDRGSAALIVFGLLSLPPLLVLASAVRARLARRLR 458

Query: 145 TLLP 148
            LLP
Sbjct: 459 PLLP 462


>gi|169173314 PREDICTED: hypothetical protein LOC286177 [Homo
           sapiens]
          Length = 287

 Score = 28.5 bits (62), Expect = 2.2
 Identities = 22/65 (33%), Positives = 28/65 (43%)

Query: 74  FHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPA 133
           F  G +     V   ARLR   G+A+    R A  +  A A W  +AL  + LL  F   
Sbjct: 100 FGRGCSCHLHAVPTRARLRAVSGHAQFVATRGAITFRGASARWGPMALLRIFLLREFGDV 159

Query: 134 ALRAA 138
            LR A
Sbjct: 160 PLREA 164


>gi|24308167 SV2 related protein [Homo sapiens]
          Length = 548

 Score = 28.1 bits (61), Expect = 2.9
 Identities = 26/82 (31%), Positives = 32/82 (39%), Gaps = 3/82 (3%)

Query: 60  FPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLV 119
           FP  L TLW+      +   ALC +++ F  L  F    R+    L  L   ARA     
Sbjct: 384 FPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRNV---LTLLLFIARAFISGG 440

Query: 120 ALAALGLLAHFLPAALRAALLG 141
             AA        P A RA  LG
Sbjct: 441 FQAAYVYTPEVYPTATRALGLG 462


>gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens]
          Length = 641

 Score = 27.7 bits (60), Expect = 3.8
 Identities = 22/57 (38%), Positives = 26/57 (45%), Gaps = 10/57 (17%)

Query: 23 SLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFL-----ATLWVAGIFF 74
          +L  +S RR     PPL  GPP F   +RA +  SE F L L      TL     FF
Sbjct: 5  ALLPLSGRRI----PPLNLGPPSFPH-HRATLRLSEKFILLLILSAFITLCFGAFFF 56


>gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo
           sapiens]
          Length = 1321

 Score = 27.3 bits (59), Expect = 5.0
 Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 8/64 (12%)

Query: 76  EGAAALCGLVYLFARLRYFQGYARSAQ------LRLAPLYASARALWLLVALAA--LGLL 127
           + A AL   +YL A++RY+ G   +AQ      L L P    A  L   + LA    G+ 
Sbjct: 496 KAAPALIDPLYLMAQVRYYSGELENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMC 555

Query: 128 AHFL 131
            H L
Sbjct: 556 FHCL 559


>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
           sapiens]
          Length = 440

 Score = 26.9 bits (58), Expect = 6.5
 Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 4/47 (8%)

Query: 102 QLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRTLLP 148
           +LR+ PL    RAL L++   +L  LA FLP  L    LG  R  +P
Sbjct: 135 KLRMTPL----RALALVLGAWSLAALASFLPLLLGWHELGHARPPVP 177


>gi|134304856 solute carrier family 6, member 7 [Homo sapiens]
          Length = 636

 Score = 26.9 bits (58), Expect = 6.5
 Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 80  ALCGLVYLFARLRY--FQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPAALRA 137
           A+CG+   F  L    F      A  +++PL+  A A  LL+ +  + +  + + A +  
Sbjct: 84  AICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLI-VGLVAIYYNMIIAYVLF 142

Query: 138 ALLGRLRTLLPW 149
            L   L + LPW
Sbjct: 143 YLFASLTSDLPW 154


>gi|169201839 PREDICTED: similar to hCG2038970 [Homo sapiens]
          Length = 915

 Score = 26.6 bits (57), Expect = 8.5
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 79  AALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLA 128
           + L G + +F       G+    Q RL+PL+   R+ WL  A AA GL+A
Sbjct: 27  SGLAGCLVIFDVAEVMAGH----QARLSPLHEQNRSFWLSKA-AAWGLVA 71


>gi|169201482 PREDICTED: similar to hCG2038970 [Homo sapiens]
          Length = 821

 Score = 26.6 bits (57), Expect = 8.5
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 79  AALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLA 128
           + L G + +F       G+    Q RL+PL+   R+ WL  A AA GL+A
Sbjct: 27  SGLAGCLVIFDVAEVMAGH----QARLSPLHEQNRSFWLSKA-AAWGLVA 71


>gi|239744229 PREDICTED: similar to hCG2038970 [Homo sapiens]
          Length = 904

 Score = 26.6 bits (57), Expect = 8.5
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 79  AALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLA 128
           + L G + +F       G+    Q RL+PL+   R+ WL  A AA GL+A
Sbjct: 27  SGLAGCLVIFDVAEVMAGH----QARLSPLHEQNRSFWLSKA-AAWGLVA 71


>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
          Length = 730

 Score = 26.6 bits (57), Expect = 8.5
 Identities = 14/29 (48%), Positives = 15/29 (51%)

Query: 108 LYASARALWLLVALAALGLLAHFLPAALR 136
           L A    LWL   LA  GL   F+P ALR
Sbjct: 221 LPAGPEFLWLWFGLAKAGLRTAFVPTALR 249


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.332    0.141    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,976,002
Number of Sequences: 37866
Number of extensions: 179419
Number of successful extensions: 539
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 533
Number of HSP's gapped (non-prelim): 16
length of query: 150
length of database: 18,247,518
effective HSP length: 93
effective length of query: 57
effective length of database: 14,725,980
effective search space: 839380860
effective search space used: 839380860
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.