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Search of human proteins with 219555716
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|219555716 synaptonemal complex central element protein 1
isoform 3 [Homo sapiens]
(318 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|219555716 synaptonemal complex central element protein 1 isof... 627 e-180
gi|219555718 synaptonemal complex central element protein 1 isof... 601 e-172
gi|18640754 synaptonemal complex central element protein 1 isofo... 560 e-160
gi|194018732 hypothetical protein LOC100130958 [Homo sapiens] 197 1e-50
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 65 1e-10
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 63 4e-10
gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein... 62 5e-10
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 62 7e-10
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 62 7e-10
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 62 7e-10
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 62 7e-10
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 62 7e-10
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 62 7e-10
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 62 7e-10
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 62 7e-10
gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-l... 61 1e-09
gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-l... 61 1e-09
gi|51317366 myosin XVIIIB [Homo sapiens] 60 3e-09
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 60 3e-09
gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-l... 60 3e-09
gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-l... 60 3e-09
gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein... 60 3e-09
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 60 3e-09
gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-l... 59 4e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 59 4e-09
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 59 6e-09
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 59 7e-09
gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein... 59 7e-09
gi|239745085 PREDICTED: similar to Golgin subfamily A member 8-l... 58 1e-08
gi|42794779 myosin 18A isoform b [Homo sapiens] 57 2e-08
>gi|219555716 synaptonemal complex central element protein 1 isoform
3 [Homo sapiens]
Length = 318
Score = 627 bits (1617), Expect = e-180
Identities = 318/318 (100%), Positives = 318/318 (100%)
Query: 1 MAGRSLTSKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRI 60
MAGRSLTSKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRI
Sbjct: 1 MAGRSLTSKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRI 60
Query: 61 NEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKE 120
NEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKE
Sbjct: 61 NEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKE 120
Query: 121 SEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPER 180
SEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPER
Sbjct: 121 SEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPER 180
Query: 181 LAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATV 240
LAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATV
Sbjct: 181 LAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATV 240
Query: 241 QLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
QLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE
Sbjct: 241 QLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
Query: 301 AGPGDVAPRPGRPVTWWS 318
AGPGDVAPRPGRPVTWWS
Sbjct: 301 AGPGDVAPRPGRPVTWWS 318
>gi|219555718 synaptonemal complex central element protein 1 isoform
4 [Homo sapiens]
Length = 351
Score = 601 bits (1549), Expect = e-172
Identities = 309/311 (99%), Positives = 310/311 (99%), Gaps = 1/311 (0%)
Query: 1 MAGRSLTSKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRI 60
MAGRSLTSKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRI
Sbjct: 1 MAGRSLTSKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRI 60
Query: 61 NEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKE 120
NEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKE
Sbjct: 61 NEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKE 120
Query: 121 SEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPER 180
SEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPER
Sbjct: 121 SEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPER 180
Query: 181 LAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATV 240
LAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATV
Sbjct: 181 LAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATV 240
Query: 241 QLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
QLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE
Sbjct: 241 QLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
Query: 301 AGPGDVA-PRP 310
AGPGDVA P+P
Sbjct: 301 AGPGDVASPKP 311
>gi|18640754 synaptonemal complex central element protein 1 isoform
1 [Homo sapiens]
Length = 282
Score = 560 bits (1442), Expect = e-160
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 37 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 96
MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV
Sbjct: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
Query: 97 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 156
HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL
Sbjct: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
Query: 157 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL 216
AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL
Sbjct: 121 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL 180
Query: 217 CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ 276
CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ
Sbjct: 181 CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ 240
Query: 277 RLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGRPVTWWS 318
RLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGRPVTWWS
Sbjct: 241 RLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGRPVTWWS 282
>gi|194018732 hypothetical protein LOC100130958 [Homo sapiens]
Length = 242
Score = 197 bits (501), Expect = 1e-50
Identities = 120/250 (48%), Positives = 158/250 (63%), Gaps = 39/250 (15%)
Query: 16 AVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLG 75
A + E+A GQ S K EDL+ MV KLQK GSLEP++E LI+RIN++QQAKKK++++L
Sbjct: 12 APEATEEAEGQ-AKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELR 70
Query: 76 EARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKE 135
E ++ EAL +ELDSL+GEKVHL+E+L KKQE LRIL++HCQEKESEA R
Sbjct: 71 ETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQR---------- 120
Query: 136 RISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE-RLAKEICALDSSKEQ 194
L QLEDLMGQHKDLW+FHM E RLA+EI AL+ SKEQ
Sbjct: 121 --------------------LDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQ 160
Query: 195 LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELL 254
LL E +LV+A L +V+ +L S EG +++GL A +++F E+ R A E+
Sbjct: 161 LLSERRLVRAKLREVERRLHSPPEVEGAMAVNDGL-------KAELEIFGEQVRSAPEVG 213
Query: 255 AAAAQRHQQL 264
A + +L
Sbjct: 214 AGEGEAGPEL 223
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 64.7 bits (156), Expect = 1e-10
Identities = 70/299 (23%), Positives = 130/299 (43%), Gaps = 36/299 (12%)
Query: 11 EPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKA 70
E +G+ ++E AG + + K+E L V KL++ + + R E ++A +
Sbjct: 1100 EHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASR-- 1157
Query: 71 NKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEK----------- 119
E + E LQ +L+ E H + L+ Q L R Q+
Sbjct: 1158 ----AERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQV 1213
Query: 120 ---ESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLR---LAFEEQLEDLMGQHKDLW 173
EA RK++++ +E +S LN Q+ E++ + ++L+ +A E+ + L + + L
Sbjct: 1214 ARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQ 1273
Query: 174 --DFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGL-- 229
R A+ AL + L +E + + E+++ +L S AE L + L
Sbjct: 1274 AETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTS--QAERAEELGQELKA 1331
Query: 230 ----FLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEK 284
F + ++A +T+QL EH + L++ QQ +Q +R +EELE+
Sbjct: 1332 WQEKFFQKEQALSTLQL---EHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQ 1387
Score = 53.9 bits (128), Expect = 2e-07
Identities = 64/298 (21%), Positives = 133/298 (44%), Gaps = 19/298 (6%)
Query: 16 AVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLG 75
A +R +D + +++E L + +K K+ L+ +++V + Q + +A ++
Sbjct: 589 AEEREASLRERDAALKQLEALEK--EKAAKLEILQQQLQVANEARDSAQTSVTQAQREKA 646
Query: 76 EARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTM---LQE 132
E E LQ +++ E+ + +++ + LR + EKE A K + LQ
Sbjct: 647 ELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQA 706
Query: 133 CKERISALNLQIEEEKNKQRQLRLAFEEQ---LEDLMGQHKDLWDFHMPER--LAKEICA 187
KE + +EEEK + A EEQ + +L + + L + H ER L +E
Sbjct: 707 LKESLKVTKGSLEEEKRRAAD---ALEEQQRCISELKAETRSLVEQHKRERKELEEERAG 763
Query: 188 LDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEH 247
+ +L + + +A E ++ +L A+ T + +E AA + +++
Sbjct: 764 RKGLEARLQQLGEAHQAETEVLRRELAEAMAAQ--HTAESECEQLVKEVAAWRERYEDSQ 821
Query: 248 RKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEE---LEKHG-MQVPAQAQSTQEEEA 301
++ + A ++ L+++C++ +Q+ Q KE+ +E H +Q+ Q E A
Sbjct: 822 QEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHA 879
Score = 48.9 bits (115), Expect = 6e-06
Identities = 67/280 (23%), Positives = 117/280 (41%), Gaps = 24/280 (8%)
Query: 26 QDTSSQKIEDLMEMV-----QKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTI 80
Q+ +SQ + +E + QK Q++ + + E R + QQ A + R
Sbjct: 542 QEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEA--TRQDHAQQLATAAEEREASLRER 599
Query: 81 CEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISAL 140
AL K+L++L EK EIL ++ + R Q ++A R+ E ++ L
Sbjct: 600 DAAL-KQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKA---ELSRKVEEL 655
Query: 141 NLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEK 200
+E + +Q + + E L + + + ER+A+E L + L + K
Sbjct: 656 QACVETARQEQHEAQAQVAELELQLRSEQQKATE---KERVAQEKDQLQEQLQALKESLK 712
Query: 201 LVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQR 260
+ K +LE+ K + L+E S+ A T L ++ R+ +EL A R
Sbjct: 713 VTKGSLEEEKRR--------AADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGR 764
Query: 261 HQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
+ L+ + QQ + Q E L + + A AQ T E E
Sbjct: 765 -KGLEARLQQLGEAHQAETEVLRRELAEAMA-AQHTAESE 802
Score = 45.4 bits (106), Expect = 7e-05
Identities = 61/300 (20%), Positives = 117/300 (39%), Gaps = 47/300 (15%)
Query: 21 EKAGGQDTSSQKIEDLMEMVQKLQKV-----GSLEPRVEVLINRINEVQQAKKKANKDLG 75
+KA ++ +Q+ + L E +Q L++ GSLE + + E Q+ +
Sbjct: 685 QKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELK---A 741
Query: 76 EARTICEALQKELDSLHGEKV-------HLKEILSKKQETLRILRLHCQEKESEAHRKHT 128
E R++ E ++E L E+ L+++ Q +LR E + H +
Sbjct: 742 ETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAES 801
Query: 129 MLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICAL 188
++ + ++A + E+ + ++ Q F+EQL L E K L
Sbjct: 802 ECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLK------------EECEKARQEL 849
Query: 189 DSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHR 248
+KE++ E + + +++L L A +Q QE+
Sbjct: 850 QEAKEKVAGIESHSELQISRQQNELAEL----------------HANLARALQQVQEKEV 893
Query: 249 KAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAP 308
+A++L A LQ+K ++ RL+ + K G Q ++ +E A GD P
Sbjct: 894 RAQKL----ADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQP 949
Score = 43.5 bits (101), Expect = 2e-04
Identities = 58/290 (20%), Positives = 133/290 (45%), Gaps = 26/290 (8%)
Query: 41 QKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKE 100
++ Q++ SL ++ I+ +++ ++ ++A++ G T ++ SL E L
Sbjct: 459 EEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTA------QVASLTSELTTLNA 512
Query: 101 ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEE----KNKQRQLRL 156
+ ++ + L L+ +EK+++ + LQ+ ++ L Q+E+ K K++QL+
Sbjct: 513 TIQQQDQELAGLKQQAKEKQAQLAQT---LQQQEQASQGLRHQVEQLSSSLKQKEQQLKE 569
Query: 157 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQL--LKEEKLVKATLEDVKHQLC 214
E+Q E H ER A + D++ +QL L++EK K + + Q+
Sbjct: 570 VAEKQ-EATRQDHAQQLATAAEEREAS-LRERDAALKQLEALEKEKAAKLEILQQQLQVA 627
Query: 215 SLCGAEGPSTLDEG------LFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKC 268
+ +++ + L + +E A V+ ++E +A+ +A + + QQK
Sbjct: 628 NEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKA 687
Query: 269 QQQQ---QKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGRPVT 315
+++ Q++ +L+E+L+ + S +EE+ D R ++
Sbjct: 688 TEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCIS 737
Score = 43.1 bits (100), Expect = 3e-04
Identities = 80/333 (24%), Positives = 132/333 (39%), Gaps = 59/333 (17%)
Query: 21 EKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTI 80
E++ + + E+ + +K ++ ++ R++ L +NE Q A K+L E R
Sbjct: 226 ERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLA-LLNEKQAASPLEPKELEELRDK 284
Query: 81 CEALQ-------KELDSLHGEKVHLKEILSKKQET-------LRILRLHCQEKE------ 120
E+L K+ L EK + +++ E LR H Q+ +
Sbjct: 285 NESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNEL 344
Query: 121 SEAHRKHTMLQECKERISALNLQIE---------EEKNKQRQLRLAFEE----QLEDLMG 167
+E H K T QE E+ + L ++ EEKN+ Q +L+ E QL+D
Sbjct: 345 TEEHSKAT--QEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPP 402
Query: 168 QHKD--LWDFHMPERLAKEICALDSSKEQLL------------KEEKLV--KATLEDVKH 211
Q K L D E L +E L ++ QL +E KL+ + E+ K
Sbjct: 403 QEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQ 462
Query: 212 QLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQ 271
QL SL + L + SQ Q Q + +A+ L QQQ
Sbjct: 463 QLSSLI-----TDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQ 517
Query: 272 QQKRQRLKEELEKHGMQVPAQAQSTQEEEAGPG 304
Q+ LK++ ++ Q+ Q Q+E+A G
Sbjct: 518 DQELAGLKQQAKEKQAQLAQTLQ--QQEQASQG 548
Score = 42.4 bits (98), Expect = 6e-04
Identities = 67/287 (23%), Positives = 115/287 (40%), Gaps = 56/287 (19%)
Query: 42 KLQKVGSL-EPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKEL----DSLHGEKV 96
+LQ++G + EVL + E A+ A + CE L KE+ + +
Sbjct: 770 RLQQLGEAHQAETEVLRRELAEAMAAQHTAESE-------CEQLVKEVAAWRERYEDSQQ 822
Query: 97 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALN----LQIEEEKNKQR 152
+ + QE L L+ C++ E LQE KE+++ + LQI ++N+
Sbjct: 823 EEAQYGAMFQEQLMTLKEECEKARQE-------LQEAKEKVAGIESHSELQISRQQNELA 875
Query: 153 QLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE----EKLVK----- 203
+L L+ + Q K++ ++LA ++ L KE E LV+
Sbjct: 876 ELHANLARALQQV--QEKEV----RAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQ 929
Query: 204 ---ATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQR 260
A+ E VK + G P L+E + ++ +T Q R+AE++ +
Sbjct: 930 QETASRELVKEP--ARAGDRQPEWLEEQ---QGRQFCSTQAALQAMEREAEQMGNELERL 984
Query: 261 HQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVA 307
L + QQQ++R G Q A+ TQE D+A
Sbjct: 985 RAALMESQGQQQEER----------GQQEREVARLTQERGRAQADLA 1021
Score = 42.0 bits (97), Expect = 7e-04
Identities = 65/304 (21%), Positives = 126/304 (41%), Gaps = 45/304 (14%)
Query: 4 RSLTSKAEPTAGAVDRAEKAGGQDTSSQKI-EDLMEMVQKLQKVGSLEPRVEVLINRINE 62
R AE A ++ ++ +QK+ +DL + +K+ R+E L+ + E
Sbjct: 869 RQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGE 928
Query: 63 VQQ-AKKKANKDLGEA-------------RTIC------EALQKELDSLHGEKVHLKEIL 102
Q+ A ++ K+ A R C +A+++E + + E L+ L
Sbjct: 929 QQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAAL 988
Query: 103 SKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAF---E 159
+ Q QE+ + R+ L + + R A +L +E+ + ++RL E
Sbjct: 989 MESQGQQ-------QEERGQQEREVARLTQERGRAQA-DLALEKAARAELEMRLQNALNE 1040
Query: 160 EQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGA 219
+++E Q E +E+ L + +KE + ++ T++ +K QL A
Sbjct: 1041 QRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQL-----A 1095
Query: 220 EGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLK 279
+ G +S+ A T + K E L A ++ L+Q+CQ+QQ++ L+
Sbjct: 1096 KKEKEHASGSGAQSEAAGRT----EPTGPKLEALRAEVSK----LEQQCQKQQEQADSLE 1147
Query: 280 EELE 283
LE
Sbjct: 1148 RSLE 1151
Score = 42.0 bits (97), Expect = 7e-04
Identities = 82/327 (25%), Positives = 143/327 (43%), Gaps = 62/327 (18%)
Query: 4 RSLTSKAEPTAGAVDRAEKAGG-----QDTSSQKIEDL----MEMVQKLQKVGSLEPRVE 54
+ LTS+AE RAE+ G Q+ QK + L +E V L P
Sbjct: 1313 QELTSQAE-------RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKH 1365
Query: 55 VLINRINEVQQAKKKANKDLGEARTICEALQKELDSLH---GEKVHLKEILSKKQETLRI 111
+ E A+K+ ++L +++ L+ EL GE + L++ +++++ T +
Sbjct: 1366 LCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQ 1425
Query: 112 LRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKD 171
LR EK S A + +ML++ ++ N + E N RQ LE + Q +
Sbjct: 1426 LRA---EKASYAEQL-SMLKKAHGLLAEENRGLGERANLGRQF-------LEVELDQAR- 1473
Query: 172 LWDFHMPERLAKEICALDSSKEQLLKE-EKLVKATLEDVKHQLCSLCGAEGPSTLDEGLF 230
E+ +E+ A+ + E L E ++ ++T +++ GA+ L+E
Sbjct: 1474 -------EKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAK-VKVLEERQR 1525
Query: 231 LRSQEAAATVQL-----FQEEHRK-AEEL---LAAAAQRHQQLQQKCQ-------QQQQK 274
+ + T Q+ FQ E K EEL LA + Q + QQK + + QQ+
Sbjct: 1526 FQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQE 1585
Query: 275 RQRLKEELEKHGMQVPAQAQSTQEEEA 301
QRL+ +L + QAQ +Q+E+A
Sbjct: 1586 AQRLQAQLNE------LQAQLSQKEQA 1606
Score = 37.7 bits (86), Expect = 0.014
Identities = 61/296 (20%), Positives = 117/296 (39%), Gaps = 63/296 (21%)
Query: 35 DLMEMVQKLQKVGSLEPRVEVL----------INRINEVQQAKKKANKDLGEARTIC-EA 83
+L E++ QKV E + L ++ + + + N+ LGE + +
Sbjct: 1405 ELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQF 1464
Query: 84 LQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQ 143
L+ ELD + V + L +R + + +E R+ Q + + +
Sbjct: 1465 LEVELDQAREKYV----------QELAAVRADAETRLAEVQRE---AQSTARELEVMTAK 1511
Query: 144 IEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMP-----ERLAKEICALDSSKEQLLKE 198
E K K + R F+E+ + L Q + L F E L+K++ DS + +++
Sbjct: 1512 YEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLA--DSDQASKVQQ 1569
Query: 199 EKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEH---------RK 249
+KL A+G + E L++Q QL Q+E K
Sbjct: 1570 QKLKAVQ-------------AQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEK 1616
Query: 250 AEELLAAAAQRHQQLQQKCQQQQQ----------KRQRLKEELEKHGMQVPAQAQS 295
A+ A Q++Q+LQ++ + +Q + +RL EL++ G++ Q+
Sbjct: 1617 AKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQT 1672
Score = 36.2 bits (82), Expect = 0.040
Identities = 52/259 (20%), Positives = 106/259 (40%), Gaps = 41/259 (15%)
Query: 17 VDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE 76
+D+A + Q+ ++ + + + + ++ S +EV+ + + + + E
Sbjct: 1469 LDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQE 1528
Query: 77 ARTICEALQKELDSLHGEKVHLKEILSKK-----------QETLRILRLHCQEKESEAHR 125
R A ++L+ E+ E LSKK Q+ L+ ++ E + EA R
Sbjct: 1529 ERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQR 1588
Query: 126 KHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEI 185
L E + ++S E K + + + ++ + + Q+++L E+L
Sbjct: 1589 LQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQ----QNQEL-----QEQLR--- 1636
Query: 186 CALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQE 245
S EQL KE K ++A E + H+L + L+++EA T +
Sbjct: 1637 -----SLEQLQKENKELRAEAERLGHEL-------------QQAGLKTKEAEQTCRHLTA 1678
Query: 246 EHRKAEELLAAAAQRHQQL 264
+ R E +A A Q+ + L
Sbjct: 1679 QVRSLEAQVAHADQQLRDL 1697
Score = 28.9 bits (63), Expect = 6.3
Identities = 33/166 (19%), Positives = 62/166 (37%), Gaps = 7/166 (4%)
Query: 1 MAGRSLTSKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRI 60
+A SK + +A+ Q + + L E+ +L + ++ + +
Sbjct: 1558 LADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKA 1617
Query: 61 NEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEIL-------SKKQETLRILR 113
AKK+ N++L E E LQKE L E L L + ++T R L
Sbjct: 1618 KTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLT 1677
Query: 114 LHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFE 159
+ E++ L++ + A + E + QL L+ +
Sbjct: 1678 AQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSID 1723
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 62.8 bits (151), Expect = 4e-10
Identities = 59/303 (19%), Positives = 146/303 (48%), Gaps = 22/303 (7%)
Query: 18 DRAEKAGGQDTSSQKIEDLM-EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE 76
++ EK Q+ ++ E++M E +K+++ + E + R E+ K++ + E
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
Query: 77 ARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHC-QEKESEAHRKHTMLQECKE 135
E +EL+ E+ ++E K+QE +I QE+E++ R+ ++E +E
Sbjct: 385 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444
Query: 136 RISALNLQI--------EEEKNKQRQLRLAFEE--QLEDLMGQHKDLWDFHMPERLAKEI 185
+I ++ E+EK ++ + R EE + E+ + + +++W E++ ++
Sbjct: 445 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW--RQKEKMHEQE 502
Query: 186 CALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQE 245
+ +E++ ++E+ ++ E ++ Q + E E ++ ++ ++++E
Sbjct: 503 EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEE 562
Query: 246 EHR--------KAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQ 297
E R + EE + ++ + ++K ++Q++KRQ +E++ K ++ Q + Q
Sbjct: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQ 622
Query: 298 EEE 300
E+E
Sbjct: 623 EQE 625
Score = 54.7 bits (130), Expect = 1e-07
Identities = 49/259 (18%), Positives = 122/259 (47%), Gaps = 17/259 (6%)
Query: 44 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTIC--EALQKELDSLHGEKVHLKEI 101
+K L+ +++++ + +E+Q K+ + L A+ + + LQ E D L E +
Sbjct: 221 EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280
Query: 102 LSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQ 161
L + E + Q++E + R+ +QE +E+I +I E++ K R EQ
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR-------EQ 333
Query: 162 LEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEG 221
E + Q + +W+ E++ ++ + +E++ ++E+++ E ++ Q E
Sbjct: 334 EEKMRRQEEMMWE--KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ------EEM 385
Query: 222 PSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEE 281
+E + ++ ++ ++E ++ EE ++ Q+ + K +Q++K + +E+
Sbjct: 386 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 445
Query: 282 LEKHGMQVPAQAQSTQEEE 300
+ + ++ Q + E+E
Sbjct: 446 IREQEKKMWRQEEKIHEQE 464
Score = 47.4 bits (111), Expect = 2e-05
Identities = 52/299 (17%), Positives = 138/299 (46%), Gaps = 26/299 (8%)
Query: 21 EKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKA---NKDLGEA 77
EK Q+ Q+ E + E ++ ++ + + E + + ++++ +KK + + E
Sbjct: 404 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 463
Query: 78 RTICEALQKELDS---LHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECK 134
I E +++ EK+H +E + +++E ++H QE++ + QE K
Sbjct: 464 EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE-----KMHEQEEKIRKQEEKVWRQEEK 518
Query: 135 ERISALNLQIEEEKNKQRQLRLAFEEQL---EDLMGQHKDLWDFH----MPERLAKEICA 187
R ++ +EEK +++ ++ +E++ E+ M + + +W+ +++ ++
Sbjct: 519 IREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK 578
Query: 188 LDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLF------LRSQEAAATVQ 241
+ +E++ ++E+ ++ E + Q + E E +R QE Q
Sbjct: 579 IREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Query: 242 LFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
+E ++ EE + ++ + ++K Q+Q++ R +E++ + ++ Q + +E+E
Sbjct: 639 --EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE 695
Score = 36.6 bits (83), Expect = 0.030
Identities = 25/167 (14%), Positives = 78/167 (46%), Gaps = 2/167 (1%)
Query: 18 DRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEA 77
++ EK Q+ ++ E+ + ++ +K+ E ++ +I E ++ ++ + + E
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQ--EQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Query: 78 RTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERI 137
+ + ++++ + +E + +++ET+ +E+E + + ++E +E +
Sbjct: 639 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM 698
Query: 138 SALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKE 184
++ E++ K + +EQ E + Q + +W+ + R +E
Sbjct: 699 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Score = 36.2 bits (82), Expect = 0.040
Identities = 37/181 (20%), Positives = 87/181 (48%), Gaps = 16/181 (8%)
Query: 26 QDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEV----QQAKKKANKDLGEARTIC 81
++ Q+ ED +M ++ +K+ E +V +I E Q+ ++K K + R
Sbjct: 561 EEEKRQEQED--KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 82 EALQKELDSLHG--EKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISA 139
E +Q++ + + EK+ +E ++++QE E+E + + +QE +E +
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEE------KMGEQEEKMCEQEEKMQEQEETMWR 672
Query: 140 LNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEE 199
+I E++ K R+ EQ E + Q + +W+ E++ ++ + +E++ ++E
Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE--QEEKMCEQEEKMQEQEEKMRRQE 730
Query: 200 K 200
+
Sbjct: 731 E 731
Score = 29.3 bits (64), Expect = 4.8
Identities = 55/241 (22%), Positives = 90/241 (37%), Gaps = 48/241 (19%)
Query: 67 KKKANKDLGEARTI---CEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEA 123
KKK N T C + + E + H + L+ L + T+RIL CQ+ E
Sbjct: 87 KKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILT--CQKTE--- 141
Query: 124 HRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAK 183
L + + ++ +QL E + DL+ + D W F A
Sbjct: 142 ----------------LQMALYYSQHAVKQL----EGEARDLISRLHDSWKFAGELEQAL 181
Query: 184 EICALDSSK-----EQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAA 238
A K E+L KE + +LE ++ + DE L ++ +
Sbjct: 182 SAVATQKKKADRYIEELTKERDAL--SLELYRNTIT-----------DEELKEKNAKLQE 228
Query: 239 TVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQE 298
+QL + E K+E L + + + K QQ+ Q + L K V A+ Q+ E
Sbjct: 229 KLQLVESE--KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 286
Query: 299 E 299
E
Sbjct: 287 E 287
>gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein 3
[Homo sapiens]
Length = 580
Score = 62.4 bits (150), Expect = 5e-10
Identities = 69/286 (24%), Positives = 129/286 (45%), Gaps = 30/286 (10%)
Query: 28 TSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQK 86
TSS ++DL Q+ V S + L N I ++Q KK+ L E + QK
Sbjct: 67 TSSATLKDLESPCQERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQK 126
Query: 87 -------ELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESE-AHRKHTMLQECKERIS 138
++ +L+ +K L L + +LR + +EK + A R LQ E S
Sbjct: 127 AKRVLEVQIQTLNIQKEELNTDLYHMKRSLR----YFEEKSKDLAVRLQHSLQRKGELES 182
Query: 139 ALNLQIEEEKNKQRQLRLAFEE-QLE-DLMGQH----KDLWDFHMPERLAKEICALDSSK 192
L+ + +K K Q + +F++ QLE D +H + W M ++++EIC L K
Sbjct: 183 VLSNVMATQKKKANQFKESFQQVQLERDEYSEHLKGERARWQQRM-RKMSQEICTLKKEK 241
Query: 193 EQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEE 252
+Q ++ + ++ +L +K+Q+ E P+ E +Q ++E +
Sbjct: 242 QQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSE----------VELQHLRKELERVAG 291
Query: 253 LLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQE 298
L A + +Q++ Q+Q+++ + +E L K ++ Q +S Q+
Sbjct: 292 ELQAQVKNNQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQ 337
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 62.0 bits (149), Expect = 7e-10
Identities = 75/265 (28%), Positives = 121/265 (45%), Gaps = 38/265 (14%)
Query: 36 LMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGE 94
L E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E
Sbjct: 2312 LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2371
Query: 95 KVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 154
+ E +S + E L++ + +E R +E +R Q EE K +
Sbjct: 2372 RQRQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRT 2420
Query: 155 RLAFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDV 209
LA +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E++
Sbjct: 2421 ELATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2476
Query: 210 K----HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQ 259
+ QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2477 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----R 2531
Query: 260 RHQQLQQKCQQQQQKRQRLKEELEK 284
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2532 EEQQRQQ--QQMEQERQRLVASMEE 2554
Score = 53.1 bits (126), Expect = 3e-07
Identities = 66/294 (22%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 19 RAEKAGGQDTSSQK-IEDLMEMVQ-KLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE 76
RAE+A Q +Q+ E L VQ + Q+ E + + E + K++A + L E
Sbjct: 1481 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1540
Query: 77 ARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQEC--K 134
R E ++ L E+ ++ + + R Q K + K L+ +
Sbjct: 1541 LRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRASFAEKTAQLERSLQE 1598
Query: 135 ERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQ 194
E ++ L+ E E+ Q+Q A E+ + + + W E L + A E+
Sbjct: 1599 EHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANEALRLRLQA-----EE 1650
Query: 195 LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELL 254
+ +++ L +A E K + G + ++A +L ++E K +L
Sbjct: 1651 VAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQRELAEQELEKQRQLA 1701
Query: 255 AAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEA 301
AQ+ +Q+ +Q +Q+RQ L+EEL + + A Q QE EA
Sbjct: 1702 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1755
Score = 51.6 bits (122), Expect = 9e-07
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 50/278 (17%)
Query: 26 QDTSSQKIEDLMEMVQKLQKVGSLEPR--------VEVLINRINEVQQAKKKANKDLGEA 77
Q+ Q + L E Q Q+ E + E L R+ E+ +A+ +A +D
Sbjct: 2347 QEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF 2406
Query: 78 RTICEALQKELDSLHGEKVHLKEILSKKQETL-RILRLHCQEKESEAHRKHTMLQECKER 136
R E + GEK+H E+ ++++ TL + L + Q+ + +A R + E
Sbjct: 2407 RKQAEEI--------GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAE---- 2454
Query: 137 ISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSS----K 192
+E EK K +Q + + E++ + E+L +E AL S K
Sbjct: 2455 -------LEREKEKLQQEAKLLQLKSEEMQTVQQ--------EQLLQETQALQQSFLSEK 2499
Query: 193 EQLLKEEKLV---KATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEE 246
+ LL+ E+ + KA LE QL A+ +E + Q E V +E
Sbjct: 2500 DSLLQRERFIEQEKAKLE----QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2555
Query: 247 HRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEK 284
R+ E ++ ++LQQ QQ++Q+ + L EE ++
Sbjct: 2556 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2593
Score = 42.7 bits (99), Expect = 4e-04
Identities = 77/316 (24%), Positives = 134/316 (42%), Gaps = 59/316 (18%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKVGS---LEPRVEVLINRIN-EVQQAKKKANKDL 74
R + +D + Q+ E + +KL +G L+ E+ + E ++ ++ A +
Sbjct: 1815 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1874
Query: 75 GEARTICEA--------------LQKELDS-LHGEKVHLKEIL-SKKQETLRILRLHCQE 118
+ R + E L+K DS L +K +++ L ++Q IL L
Sbjct: 1875 FQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1934
Query: 119 KESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDF 175
+++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1935 EKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE------- 1987
Query: 176 HMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRS-- 233
ER+ K + A + + Q KA LE+V+ + ++E LR
Sbjct: 1988 ---ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEARRLRERA 2028
Query: 234 -QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKEELE--KH 285
QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+ E E +
Sbjct: 2029 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2088
Query: 286 GMQVPAQAQSTQEEEA 301
+ +A+ E EA
Sbjct: 2089 AAEEAEEARVQAEREA 2104
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/293 (19%), Positives = 132/293 (45%), Gaps = 51/293 (17%)
Query: 8 SKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAK 67
++ EP A + + G ++ Q+ DL +L + S ++ + + +++ +
Sbjct: 1291 AQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTS--QYIKFISETLRRMEEEE 1348
Query: 68 KKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKH 127
+ A + E E+ L E+ + ++ ++ H Q K ++A R+
Sbjct: 1349 RLAEQQRAE-----------------ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE- 1389
Query: 128 TMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICA 187
+E ++R+ ++ EE +Q + + +E+L+ L + + A++ A
Sbjct: 1390 --AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEA-----EIQAKARQAEA 1442
Query: 188 LDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEH 247
+ S+ ++ +E ++V+ LE + Q GAEG + L R++EA A + QEE
Sbjct: 1443 AERSRLRIEEEIRVVRLQLEATERQRG---GAEGEL---QALRARAEEAEAQKRQAQEE- 1495
Query: 248 RKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++L+++ Q + Q++++ + EL +V A+A++ +E++
Sbjct: 1496 -------------AERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAAREKQ 1532
Score = 40.0 bits (92), Expect = 0.003
Identities = 62/262 (23%), Positives = 109/262 (41%), Gaps = 26/262 (9%)
Query: 34 EDLMEMVQKLQKVGSLEPRVEVLINRI--NEVQQAKKKANKDLGEARTICEALQKELDSL 91
E+++ + +K + + +E+ + RI N + K +L AR A ++E
Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1984
Query: 92 HGEKVHLKEILSKKQETLRILRLHCQEKE------SEAHRKHTMLQECKERISALNLQIE 145
E+ +++ L+ ++E R + +E E EA R L+E E+ SA LQ+
Sbjct: 1985 EAEE-RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARR----LRERAEQESARQLQLA 2039
Query: 146 EEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKAT 205
+E Q RL EE+ Q K+ + + L +E LD QL E + +
Sbjct: 2040 QEA---AQKRLQAEEKAHAFAVQQKEQ---ELQQTLQQEQSVLD----QLRGEAEAARRA 2089
Query: 206 LEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQ 263
E+ + A+ ++E L+ Q A Q + AE+L A Q +
Sbjct: 2090 AEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2148
Query: 264 LQQKCQQQQQKRQRLKEELEKH 285
Q Q +++Q E+EKH
Sbjct: 2149 RAQAEQAALRQKQAADAEMEKH 2170
Score = 40.0 bits (92), Expect = 0.003
Identities = 70/329 (21%), Positives = 136/329 (41%), Gaps = 52/329 (15%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKKKANKDLGEA 77
+AE+ QK ++L + +Q+ Q V L E E ++A+ +A ++ ++
Sbjct: 2048 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2107
Query: 78 RTICEALQK------ELDSLHGEKVHLKEILSKKQETLRILRLHCQEK----------ES 121
R E ++ E + E L K+ E R ++ E
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2167
Query: 122 EAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL-----------------RLAFE 159
E H+K T+ Q+ + + ++ L LQ+EE +++ L R E
Sbjct: 2168 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2227
Query: 160 EQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLEDVKHQL 213
E+L + Q ++L + R+ E AL D+++ L +E EK+ + E + +
Sbjct: 2228 EELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2285
Query: 214 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQQKCQQQ 271
+ A +E L +Q+ A ++ +E+ + +E L A A+ QQ ++ Q+Q
Sbjct: 2286 AAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2342
Query: 272 QQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++ Q KE++ + + Q T E E
Sbjct: 2343 ARRLQEDKEQMAQQLAEETQGFQRTLEAE 2371
Score = 30.8 bits (68), Expect = 1.7
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 104 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 163
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1228 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1284
Query: 164 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 215
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1285 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1340
Query: 216 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 275
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1341 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1397
Query: 276 QRLKEELEKHGMQVPAQAQSTQEE 299
Q E+ + Q +S QEE
Sbjct: 1398 QEEVVRREEAAVDAQQQKRSIQEE 1421
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 62.0 bits (149), Expect = 7e-10
Identities = 75/265 (28%), Positives = 121/265 (45%), Gaps = 38/265 (14%)
Query: 36 LMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGE 94
L E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E
Sbjct: 2316 LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2375
Query: 95 KVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 154
+ E +S + E L++ + +E R +E +R Q EE K +
Sbjct: 2376 RQRQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRT 2424
Query: 155 RLAFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDV 209
LA +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E++
Sbjct: 2425 ELATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2480
Query: 210 K----HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQ 259
+ QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2481 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----R 2535
Query: 260 RHQQLQQKCQQQQQKRQRLKEELEK 284
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2536 EEQQRQQ--QQMEQERQRLVASMEE 2558
Score = 53.1 bits (126), Expect = 3e-07
Identities = 66/294 (22%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 19 RAEKAGGQDTSSQK-IEDLMEMVQ-KLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE 76
RAE+A Q +Q+ E L VQ + Q+ E + + E + K++A + L E
Sbjct: 1485 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1544
Query: 77 ARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQEC--K 134
R E ++ L E+ ++ + + R Q K + K L+ +
Sbjct: 1545 LRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRASFAEKTAQLERSLQE 1602
Query: 135 ERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQ 194
E ++ L+ E E+ Q+Q A E+ + + + W E L + A E+
Sbjct: 1603 EHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANEALRLRLQA-----EE 1654
Query: 195 LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELL 254
+ +++ L +A E K + G + ++A +L ++E K +L
Sbjct: 1655 VAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQRELAEQELEKQRQLA 1705
Query: 255 AAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEA 301
AQ+ +Q+ +Q +Q+RQ L+EEL + + A Q QE EA
Sbjct: 1706 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1759
Score = 51.6 bits (122), Expect = 9e-07
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 50/278 (17%)
Query: 26 QDTSSQKIEDLMEMVQKLQKVGSLEPR--------VEVLINRINEVQQAKKKANKDLGEA 77
Q+ Q + L E Q Q+ E + E L R+ E+ +A+ +A +D
Sbjct: 2351 QEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF 2410
Query: 78 RTICEALQKELDSLHGEKVHLKEILSKKQETL-RILRLHCQEKESEAHRKHTMLQECKER 136
R E + GEK+H E+ ++++ TL + L + Q+ + +A R + E
Sbjct: 2411 RKQAEEI--------GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAE---- 2458
Query: 137 ISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSS----K 192
+E EK K +Q + + E++ + E+L +E AL S K
Sbjct: 2459 -------LEREKEKLQQEAKLLQLKSEEMQTVQQ--------EQLLQETQALQQSFLSEK 2503
Query: 193 EQLLKEEKLV---KATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEE 246
+ LL+ E+ + KA LE QL A+ +E + Q E V +E
Sbjct: 2504 DSLLQRERFIEQEKAKLE----QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2559
Query: 247 HRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEK 284
R+ E ++ ++LQQ QQ++Q+ + L EE ++
Sbjct: 2560 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2597
Score = 42.7 bits (99), Expect = 4e-04
Identities = 77/316 (24%), Positives = 134/316 (42%), Gaps = 59/316 (18%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKVGS---LEPRVEVLINRIN-EVQQAKKKANKDL 74
R + +D + Q+ E + +KL +G L+ E+ + E ++ ++ A +
Sbjct: 1819 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1878
Query: 75 GEARTICEA--------------LQKELDS-LHGEKVHLKEIL-SKKQETLRILRLHCQE 118
+ R + E L+K DS L +K +++ L ++Q IL L
Sbjct: 1879 FQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1938
Query: 119 KESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDF 175
+++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1939 EKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE------- 1991
Query: 176 HMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRS-- 233
ER+ K + A + + Q KA LE+V+ + ++E LR
Sbjct: 1992 ---ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEARRLRERA 2032
Query: 234 -QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKEELE--KH 285
QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+ E E +
Sbjct: 2033 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2092
Query: 286 GMQVPAQAQSTQEEEA 301
+ +A+ E EA
Sbjct: 2093 AAEEAEEARVQAEREA 2108
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/293 (19%), Positives = 132/293 (45%), Gaps = 51/293 (17%)
Query: 8 SKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAK 67
++ EP A + + G ++ Q+ DL +L + S ++ + + +++ +
Sbjct: 1295 AQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTS--QYIKFISETLRRMEEEE 1352
Query: 68 KKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKH 127
+ A + E E+ L E+ + ++ ++ H Q K ++A R+
Sbjct: 1353 RLAEQQRAE-----------------ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE- 1393
Query: 128 TMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICA 187
+E ++R+ ++ EE +Q + + +E+L+ L + + A++ A
Sbjct: 1394 --AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEA-----EIQAKARQAEA 1446
Query: 188 LDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEH 247
+ S+ ++ +E ++V+ LE + Q GAEG + L R++EA A + QEE
Sbjct: 1447 AERSRLRIEEEIRVVRLQLEATERQRG---GAEGEL---QALRARAEEAEAQKRQAQEE- 1499
Query: 248 RKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++L+++ Q + Q++++ + EL +V A+A++ +E++
Sbjct: 1500 -------------AERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAAREKQ 1536
Score = 40.0 bits (92), Expect = 0.003
Identities = 62/262 (23%), Positives = 109/262 (41%), Gaps = 26/262 (9%)
Query: 34 EDLMEMVQKLQKVGSLEPRVEVLINRI--NEVQQAKKKANKDLGEARTICEALQKELDSL 91
E+++ + +K + + +E+ + RI N + K +L AR A ++E
Sbjct: 1929 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1988
Query: 92 HGEKVHLKEILSKKQETLRILRLHCQEKE------SEAHRKHTMLQECKERISALNLQIE 145
E+ +++ L+ ++E R + +E E EA R L+E E+ SA LQ+
Sbjct: 1989 EAEE-RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARR----LRERAEQESARQLQLA 2043
Query: 146 EEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKAT 205
+E Q RL EE+ Q K+ + + L +E LD QL E + +
Sbjct: 2044 QEA---AQKRLQAEEKAHAFAVQQKEQ---ELQQTLQQEQSVLD----QLRGEAEAARRA 2093
Query: 206 LEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQ 263
E+ + A+ ++E L+ Q A Q + AE+L A Q +
Sbjct: 2094 AEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2152
Query: 264 LQQKCQQQQQKRQRLKEELEKH 285
Q Q +++Q E+EKH
Sbjct: 2153 RAQAEQAALRQKQAADAEMEKH 2174
Score = 40.0 bits (92), Expect = 0.003
Identities = 70/329 (21%), Positives = 136/329 (41%), Gaps = 52/329 (15%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKKKANKDLGEA 77
+AE+ QK ++L + +Q+ Q V L E E ++A+ +A ++ ++
Sbjct: 2052 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2111
Query: 78 RTICEALQK------ELDSLHGEKVHLKEILSKKQETLRILRLHCQEK----------ES 121
R E ++ E + E L K+ E R ++ E
Sbjct: 2112 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2171
Query: 122 EAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL-----------------RLAFE 159
E H+K T+ Q+ + + ++ L LQ+EE +++ L R E
Sbjct: 2172 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2231
Query: 160 EQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLEDVKHQL 213
E+L + Q ++L + R+ E AL D+++ L +E EK+ + E + +
Sbjct: 2232 EELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2289
Query: 214 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQQKCQQQ 271
+ A +E L +Q+ A ++ +E+ + +E L A A+ QQ ++ Q+Q
Sbjct: 2290 AAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2346
Query: 272 QQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++ Q KE++ + + Q T E E
Sbjct: 2347 ARRLQEDKEQMAQQLAEETQGFQRTLEAE 2375
Score = 30.8 bits (68), Expect = 1.7
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 104 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 163
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1232 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1288
Query: 164 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 215
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1289 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1344
Query: 216 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 275
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1345 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1401
Query: 276 QRLKEELEKHGMQVPAQAQSTQEE 299
Q E+ + Q +S QEE
Sbjct: 1402 QEEVVRREEAAVDAQQQKRSIQEE 1425
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 62.0 bits (149), Expect = 7e-10
Identities = 75/265 (28%), Positives = 121/265 (45%), Gaps = 38/265 (14%)
Query: 36 LMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGE 94
L E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E
Sbjct: 2312 LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2371
Query: 95 KVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 154
+ E +S + E L++ + +E R +E +R Q EE K +
Sbjct: 2372 RQRQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRT 2420
Query: 155 RLAFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDV 209
LA +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E++
Sbjct: 2421 ELATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2476
Query: 210 K----HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQ 259
+ QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2477 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----R 2531
Query: 260 RHQQLQQKCQQQQQKRQRLKEELEK 284
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2532 EEQQRQQ--QQMEQERQRLVASMEE 2554
Score = 53.1 bits (126), Expect = 3e-07
Identities = 66/294 (22%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 19 RAEKAGGQDTSSQK-IEDLMEMVQ-KLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE 76
RAE+A Q +Q+ E L VQ + Q+ E + + E + K++A + L E
Sbjct: 1481 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1540
Query: 77 ARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQEC--K 134
R E ++ L E+ ++ + + R Q K + K L+ +
Sbjct: 1541 LRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRASFAEKTAQLERSLQE 1598
Query: 135 ERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQ 194
E ++ L+ E E+ Q+Q A E+ + + + W E L + A E+
Sbjct: 1599 EHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANEALRLRLQA-----EE 1650
Query: 195 LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELL 254
+ +++ L +A E K + G + ++A +L ++E K +L
Sbjct: 1651 VAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQRELAEQELEKQRQLA 1701
Query: 255 AAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEA 301
AQ+ +Q+ +Q +Q+RQ L+EEL + + A Q QE EA
Sbjct: 1702 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1755
Score = 51.6 bits (122), Expect = 9e-07
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 50/278 (17%)
Query: 26 QDTSSQKIEDLMEMVQKLQKVGSLEPR--------VEVLINRINEVQQAKKKANKDLGEA 77
Q+ Q + L E Q Q+ E + E L R+ E+ +A+ +A +D
Sbjct: 2347 QEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF 2406
Query: 78 RTICEALQKELDSLHGEKVHLKEILSKKQETL-RILRLHCQEKESEAHRKHTMLQECKER 136
R E + GEK+H E+ ++++ TL + L + Q+ + +A R + E
Sbjct: 2407 RKQAEEI--------GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAE---- 2454
Query: 137 ISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSS----K 192
+E EK K +Q + + E++ + E+L +E AL S K
Sbjct: 2455 -------LEREKEKLQQEAKLLQLKSEEMQTVQQ--------EQLLQETQALQQSFLSEK 2499
Query: 193 EQLLKEEKLV---KATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEE 246
+ LL+ E+ + KA LE QL A+ +E + Q E V +E
Sbjct: 2500 DSLLQRERFIEQEKAKLE----QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2555
Query: 247 HRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEK 284
R+ E ++ ++LQQ QQ++Q+ + L EE ++
Sbjct: 2556 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2593
Score = 42.7 bits (99), Expect = 4e-04
Identities = 77/316 (24%), Positives = 134/316 (42%), Gaps = 59/316 (18%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKVGS---LEPRVEVLINRIN-EVQQAKKKANKDL 74
R + +D + Q+ E + +KL +G L+ E+ + E ++ ++ A +
Sbjct: 1815 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1874
Query: 75 GEARTICEA--------------LQKELDS-LHGEKVHLKEIL-SKKQETLRILRLHCQE 118
+ R + E L+K DS L +K +++ L ++Q IL L
Sbjct: 1875 FQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1934
Query: 119 KESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDF 175
+++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1935 EKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE------- 1987
Query: 176 HMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRS-- 233
ER+ K + A + + Q KA LE+V+ + ++E LR
Sbjct: 1988 ---ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEARRLRERA 2028
Query: 234 -QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKEELE--KH 285
QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+ E E +
Sbjct: 2029 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2088
Query: 286 GMQVPAQAQSTQEEEA 301
+ +A+ E EA
Sbjct: 2089 AAEEAEEARVQAEREA 2104
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/293 (19%), Positives = 132/293 (45%), Gaps = 51/293 (17%)
Query: 8 SKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAK 67
++ EP A + + G ++ Q+ DL +L + S ++ + + +++ +
Sbjct: 1291 AQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTS--QYIKFISETLRRMEEEE 1348
Query: 68 KKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKH 127
+ A + E E+ L E+ + ++ ++ H Q K ++A R+
Sbjct: 1349 RLAEQQRAE-----------------ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE- 1389
Query: 128 TMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICA 187
+E ++R+ ++ EE +Q + + +E+L+ L + + A++ A
Sbjct: 1390 --AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEA-----EIQAKARQAEA 1442
Query: 188 LDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEH 247
+ S+ ++ +E ++V+ LE + Q GAEG + L R++EA A + QEE
Sbjct: 1443 AERSRLRIEEEIRVVRLQLEATERQRG---GAEGEL---QALRARAEEAEAQKRQAQEE- 1495
Query: 248 RKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++L+++ Q + Q++++ + EL +V A+A++ +E++
Sbjct: 1496 -------------AERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAAREKQ 1532
Score = 40.0 bits (92), Expect = 0.003
Identities = 62/262 (23%), Positives = 109/262 (41%), Gaps = 26/262 (9%)
Query: 34 EDLMEMVQKLQKVGSLEPRVEVLINRI--NEVQQAKKKANKDLGEARTICEALQKELDSL 91
E+++ + +K + + +E+ + RI N + K +L AR A ++E
Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1984
Query: 92 HGEKVHLKEILSKKQETLRILRLHCQEKE------SEAHRKHTMLQECKERISALNLQIE 145
E+ +++ L+ ++E R + +E E EA R L+E E+ SA LQ+
Sbjct: 1985 EAEE-RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARR----LRERAEQESARQLQLA 2039
Query: 146 EEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKAT 205
+E Q RL EE+ Q K+ + + L +E LD QL E + +
Sbjct: 2040 QEA---AQKRLQAEEKAHAFAVQQKEQ---ELQQTLQQEQSVLD----QLRGEAEAARRA 2089
Query: 206 LEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQ 263
E+ + A+ ++E L+ Q A Q + AE+L A Q +
Sbjct: 2090 AEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2148
Query: 264 LQQKCQQQQQKRQRLKEELEKH 285
Q Q +++Q E+EKH
Sbjct: 2149 RAQAEQAALRQKQAADAEMEKH 2170
Score = 40.0 bits (92), Expect = 0.003
Identities = 70/329 (21%), Positives = 136/329 (41%), Gaps = 52/329 (15%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKKKANKDLGEA 77
+AE+ QK ++L + +Q+ Q V L E E ++A+ +A ++ ++
Sbjct: 2048 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2107
Query: 78 RTICEALQK------ELDSLHGEKVHLKEILSKKQETLRILRLHCQEK----------ES 121
R E ++ E + E L K+ E R ++ E
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2167
Query: 122 EAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL-----------------RLAFE 159
E H+K T+ Q+ + + ++ L LQ+EE +++ L R E
Sbjct: 2168 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2227
Query: 160 EQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLEDVKHQL 213
E+L + Q ++L + R+ E AL D+++ L +E EK+ + E + +
Sbjct: 2228 EELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2285
Query: 214 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQQKCQQQ 271
+ A +E L +Q+ A ++ +E+ + +E L A A+ QQ ++ Q+Q
Sbjct: 2286 AAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2342
Query: 272 QQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++ Q KE++ + + Q T E E
Sbjct: 2343 ARRLQEDKEQMAQQLAEETQGFQRTLEAE 2371
Score = 30.8 bits (68), Expect = 1.7
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 104 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 163
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1228 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1284
Query: 164 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 215
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1285 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1340
Query: 216 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 275
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1341 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1397
Query: 276 QRLKEELEKHGMQVPAQAQSTQEE 299
Q E+ + Q +S QEE
Sbjct: 1398 QEEVVRREEAAVDAQQQKRSIQEE 1421
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 62.0 bits (149), Expect = 7e-10
Identities = 75/265 (28%), Positives = 121/265 (45%), Gaps = 38/265 (14%)
Query: 36 LMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGE 94
L E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E
Sbjct: 2280 LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2339
Query: 95 KVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 154
+ E +S + E L++ + +E R +E +R Q EE K +
Sbjct: 2340 RQRQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRT 2388
Query: 155 RLAFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDV 209
LA +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E++
Sbjct: 2389 ELATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2444
Query: 210 K----HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQ 259
+ QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2445 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----R 2499
Query: 260 RHQQLQQKCQQQQQKRQRLKEELEK 284
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2500 EEQQRQQ--QQMEQERQRLVASMEE 2522
Score = 53.1 bits (126), Expect = 3e-07
Identities = 66/294 (22%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 19 RAEKAGGQDTSSQK-IEDLMEMVQ-KLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE 76
RAE+A Q +Q+ E L VQ + Q+ E + + E + K++A + L E
Sbjct: 1449 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1508
Query: 77 ARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQEC--K 134
R E ++ L E+ ++ + + R Q K + K L+ +
Sbjct: 1509 LRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRASFAEKTAQLERSLQE 1566
Query: 135 ERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQ 194
E ++ L+ E E+ Q+Q A E+ + + + W E L + A E+
Sbjct: 1567 EHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANEALRLRLQA-----EE 1618
Query: 195 LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELL 254
+ +++ L +A E K + G + ++A +L ++E K +L
Sbjct: 1619 VAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQRELAEQELEKQRQLA 1669
Query: 255 AAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEA 301
AQ+ +Q+ +Q +Q+RQ L+EEL + + A Q QE EA
Sbjct: 1670 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1723
Score = 51.6 bits (122), Expect = 9e-07
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 50/278 (17%)
Query: 26 QDTSSQKIEDLMEMVQKLQKVGSLEPR--------VEVLINRINEVQQAKKKANKDLGEA 77
Q+ Q + L E Q Q+ E + E L R+ E+ +A+ +A +D
Sbjct: 2315 QEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF 2374
Query: 78 RTICEALQKELDSLHGEKVHLKEILSKKQETL-RILRLHCQEKESEAHRKHTMLQECKER 136
R E + GEK+H E+ ++++ TL + L + Q+ + +A R + E
Sbjct: 2375 RKQAEEI--------GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAE---- 2422
Query: 137 ISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSS----K 192
+E EK K +Q + + E++ + E+L +E AL S K
Sbjct: 2423 -------LEREKEKLQQEAKLLQLKSEEMQTVQQ--------EQLLQETQALQQSFLSEK 2467
Query: 193 EQLLKEEKLV---KATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEE 246
+ LL+ E+ + KA LE QL A+ +E + Q E V +E
Sbjct: 2468 DSLLQRERFIEQEKAKLE----QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2523
Query: 247 HRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEK 284
R+ E ++ ++LQQ QQ++Q+ + L EE ++
Sbjct: 2524 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2561
Score = 42.7 bits (99), Expect = 4e-04
Identities = 77/316 (24%), Positives = 134/316 (42%), Gaps = 59/316 (18%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKVGS---LEPRVEVLINRIN-EVQQAKKKANKDL 74
R + +D + Q+ E + +KL +G L+ E+ + E ++ ++ A +
Sbjct: 1783 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1842
Query: 75 GEARTICEA--------------LQKELDS-LHGEKVHLKEIL-SKKQETLRILRLHCQE 118
+ R + E L+K DS L +K +++ L ++Q IL L
Sbjct: 1843 FQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1902
Query: 119 KESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDF 175
+++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1903 EKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE------- 1955
Query: 176 HMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRS-- 233
ER+ K + A + + Q KA LE+V+ + ++E LR
Sbjct: 1956 ---ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEARRLRERA 1996
Query: 234 -QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKEELE--KH 285
QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+ E E +
Sbjct: 1997 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2056
Query: 286 GMQVPAQAQSTQEEEA 301
+ +A+ E EA
Sbjct: 2057 AAEEAEEARVQAEREA 2072
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/293 (19%), Positives = 132/293 (45%), Gaps = 51/293 (17%)
Query: 8 SKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAK 67
++ EP A + + G ++ Q+ DL +L + S ++ + + +++ +
Sbjct: 1259 AQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTS--QYIKFISETLRRMEEEE 1316
Query: 68 KKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKH 127
+ A + E E+ L E+ + ++ ++ H Q K ++A R+
Sbjct: 1317 RLAEQQRAE-----------------ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE- 1357
Query: 128 TMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICA 187
+E ++R+ ++ EE +Q + + +E+L+ L + + A++ A
Sbjct: 1358 --AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEA-----EIQAKARQAEA 1410
Query: 188 LDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEH 247
+ S+ ++ +E ++V+ LE + Q GAEG + L R++EA A + QEE
Sbjct: 1411 AERSRLRIEEEIRVVRLQLEATERQRG---GAEGEL---QALRARAEEAEAQKRQAQEE- 1463
Query: 248 RKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++L+++ Q + Q++++ + EL +V A+A++ +E++
Sbjct: 1464 -------------AERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAAREKQ 1500
Score = 40.0 bits (92), Expect = 0.003
Identities = 62/262 (23%), Positives = 109/262 (41%), Gaps = 26/262 (9%)
Query: 34 EDLMEMVQKLQKVGSLEPRVEVLINRI--NEVQQAKKKANKDLGEARTICEALQKELDSL 91
E+++ + +K + + +E+ + RI N + K +L AR A ++E
Sbjct: 1893 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1952
Query: 92 HGEKVHLKEILSKKQETLRILRLHCQEKE------SEAHRKHTMLQECKERISALNLQIE 145
E+ +++ L+ ++E R + +E E EA R L+E E+ SA LQ+
Sbjct: 1953 EAEE-RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARR----LRERAEQESARQLQLA 2007
Query: 146 EEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKAT 205
+E Q RL EE+ Q K+ + + L +E LD QL E + +
Sbjct: 2008 QEA---AQKRLQAEEKAHAFAVQQKEQ---ELQQTLQQEQSVLD----QLRGEAEAARRA 2057
Query: 206 LEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQ 263
E+ + A+ ++E L+ Q A Q + AE+L A Q +
Sbjct: 2058 AEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2116
Query: 264 LQQKCQQQQQKRQRLKEELEKH 285
Q Q +++Q E+EKH
Sbjct: 2117 RAQAEQAALRQKQAADAEMEKH 2138
Score = 40.0 bits (92), Expect = 0.003
Identities = 70/329 (21%), Positives = 136/329 (41%), Gaps = 52/329 (15%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKKKANKDLGEA 77
+AE+ QK ++L + +Q+ Q V L E E ++A+ +A ++ ++
Sbjct: 2016 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2075
Query: 78 RTICEALQK------ELDSLHGEKVHLKEILSKKQETLRILRLHCQEK----------ES 121
R E ++ E + E L K+ E R ++ E
Sbjct: 2076 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2135
Query: 122 EAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL-----------------RLAFE 159
E H+K T+ Q+ + + ++ L LQ+EE +++ L R E
Sbjct: 2136 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2195
Query: 160 EQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLEDVKHQL 213
E+L + Q ++L + R+ E AL D+++ L +E EK+ + E + +
Sbjct: 2196 EELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2253
Query: 214 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQQKCQQQ 271
+ A +E L +Q+ A ++ +E+ + +E L A A+ QQ ++ Q+Q
Sbjct: 2254 AAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2310
Query: 272 QQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++ Q KE++ + + Q T E E
Sbjct: 2311 ARRLQEDKEQMAQQLAEETQGFQRTLEAE 2339
Score = 30.8 bits (68), Expect = 1.7
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 104 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 163
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1196 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1252
Query: 164 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 215
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1253 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1308
Query: 216 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 275
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1309 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1365
Query: 276 QRLKEELEKHGMQVPAQAQSTQEE 299
Q E+ + Q +S QEE
Sbjct: 1366 QEEVVRREEAAVDAQQQKRSIQEE 1389
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 62.0 bits (149), Expect = 7e-10
Identities = 75/265 (28%), Positives = 121/265 (45%), Gaps = 38/265 (14%)
Query: 36 LMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGE 94
L E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E
Sbjct: 2449 LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2508
Query: 95 KVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 154
+ E +S + E L++ + +E R +E +R Q EE K +
Sbjct: 2509 RQRQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRT 2557
Query: 155 RLAFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDV 209
LA +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E++
Sbjct: 2558 ELATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2613
Query: 210 K----HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQ 259
+ QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2614 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----R 2668
Query: 260 RHQQLQQKCQQQQQKRQRLKEELEK 284
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2669 EEQQRQQ--QQMEQERQRLVASMEE 2691
Score = 53.1 bits (126), Expect = 3e-07
Identities = 66/294 (22%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 19 RAEKAGGQDTSSQK-IEDLMEMVQ-KLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE 76
RAE+A Q +Q+ E L VQ + Q+ E + + E + K++A + L E
Sbjct: 1618 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1677
Query: 77 ARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQEC--K 134
R E ++ L E+ ++ + + R Q K + K L+ +
Sbjct: 1678 LRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRASFAEKTAQLERSLQE 1735
Query: 135 ERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQ 194
E ++ L+ E E+ Q+Q A E+ + + + W E L + A E+
Sbjct: 1736 EHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANEALRLRLQA-----EE 1787
Query: 195 LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELL 254
+ +++ L +A E K + G + ++A +L ++E K +L
Sbjct: 1788 VAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQRELAEQELEKQRQLA 1838
Query: 255 AAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEA 301
AQ+ +Q+ +Q +Q+RQ L+EEL + + A Q QE EA
Sbjct: 1839 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1892
Score = 51.6 bits (122), Expect = 9e-07
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 50/278 (17%)
Query: 26 QDTSSQKIEDLMEMVQKLQKVGSLEPR--------VEVLINRINEVQQAKKKANKDLGEA 77
Q+ Q + L E Q Q+ E + E L R+ E+ +A+ +A +D
Sbjct: 2484 QEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF 2543
Query: 78 RTICEALQKELDSLHGEKVHLKEILSKKQETL-RILRLHCQEKESEAHRKHTMLQECKER 136
R E + GEK+H E+ ++++ TL + L + Q+ + +A R + E
Sbjct: 2544 RKQAEEI--------GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAE---- 2591
Query: 137 ISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSS----K 192
+E EK K +Q + + E++ + E+L +E AL S K
Sbjct: 2592 -------LEREKEKLQQEAKLLQLKSEEMQTVQQ--------EQLLQETQALQQSFLSEK 2636
Query: 193 EQLLKEEKLV---KATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEE 246
+ LL+ E+ + KA LE QL A+ +E + Q E V +E
Sbjct: 2637 DSLLQRERFIEQEKAKLE----QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2692
Query: 247 HRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEK 284
R+ E ++ ++LQQ QQ++Q+ + L EE ++
Sbjct: 2693 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2730
Score = 42.7 bits (99), Expect = 4e-04
Identities = 77/316 (24%), Positives = 134/316 (42%), Gaps = 59/316 (18%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKVGS---LEPRVEVLINRIN-EVQQAKKKANKDL 74
R + +D + Q+ E + +KL +G L+ E+ + E ++ ++ A +
Sbjct: 1952 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 2011
Query: 75 GEARTICEA--------------LQKELDS-LHGEKVHLKEIL-SKKQETLRILRLHCQE 118
+ R + E L+K DS L +K +++ L ++Q IL L
Sbjct: 2012 FQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 2071
Query: 119 KESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDF 175
+++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 2072 EKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE------- 2124
Query: 176 HMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRS-- 233
ER+ K + A + + Q KA LE+V+ + ++E LR
Sbjct: 2125 ---ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEARRLRERA 2165
Query: 234 -QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKEELE--KH 285
QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+ E E +
Sbjct: 2166 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2225
Query: 286 GMQVPAQAQSTQEEEA 301
+ +A+ E EA
Sbjct: 2226 AAEEAEEARVQAEREA 2241
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/293 (19%), Positives = 132/293 (45%), Gaps = 51/293 (17%)
Query: 8 SKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAK 67
++ EP A + + G ++ Q+ DL +L + S ++ + + +++ +
Sbjct: 1428 AQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTS--QYIKFISETLRRMEEEE 1485
Query: 68 KKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKH 127
+ A + E E+ L E+ + ++ ++ H Q K ++A R+
Sbjct: 1486 RLAEQQRAE-----------------ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE- 1526
Query: 128 TMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICA 187
+E ++R+ ++ EE +Q + + +E+L+ L + + A++ A
Sbjct: 1527 --AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEA-----EIQAKARQAEA 1579
Query: 188 LDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEH 247
+ S+ ++ +E ++V+ LE + Q GAEG + L R++EA A + QEE
Sbjct: 1580 AERSRLRIEEEIRVVRLQLEATERQRG---GAEGEL---QALRARAEEAEAQKRQAQEE- 1632
Query: 248 RKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++L+++ Q + Q++++ + EL +V A+A++ +E++
Sbjct: 1633 -------------AERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAAREKQ 1669
Score = 40.0 bits (92), Expect = 0.003
Identities = 62/262 (23%), Positives = 109/262 (41%), Gaps = 26/262 (9%)
Query: 34 EDLMEMVQKLQKVGSLEPRVEVLINRI--NEVQQAKKKANKDLGEARTICEALQKELDSL 91
E+++ + +K + + +E+ + RI N + K +L AR A ++E
Sbjct: 2062 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 2121
Query: 92 HGEKVHLKEILSKKQETLRILRLHCQEKE------SEAHRKHTMLQECKERISALNLQIE 145
E+ +++ L+ ++E R + +E E EA R L+E E+ SA LQ+
Sbjct: 2122 EAEE-RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARR----LRERAEQESARQLQLA 2176
Query: 146 EEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKAT 205
+E Q RL EE+ Q K+ + + L +E LD QL E + +
Sbjct: 2177 QEA---AQKRLQAEEKAHAFAVQQKEQ---ELQQTLQQEQSVLD----QLRGEAEAARRA 2226
Query: 206 LEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQ 263
E+ + A+ ++E L+ Q A Q + AE+L A Q +
Sbjct: 2227 AEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2285
Query: 264 LQQKCQQQQQKRQRLKEELEKH 285
Q Q +++Q E+EKH
Sbjct: 2286 RAQAEQAALRQKQAADAEMEKH 2307
Score = 40.0 bits (92), Expect = 0.003
Identities = 70/329 (21%), Positives = 136/329 (41%), Gaps = 52/329 (15%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKKKANKDLGEA 77
+AE+ QK ++L + +Q+ Q V L E E ++A+ +A ++ ++
Sbjct: 2185 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2244
Query: 78 RTICEALQK------ELDSLHGEKVHLKEILSKKQETLRILRLHCQEK----------ES 121
R E ++ E + E L K+ E R ++ E
Sbjct: 2245 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2304
Query: 122 EAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL-----------------RLAFE 159
E H+K T+ Q+ + + ++ L LQ+EE +++ L R E
Sbjct: 2305 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2364
Query: 160 EQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLEDVKHQL 213
E+L + Q ++L + R+ E AL D+++ L +E EK+ + E + +
Sbjct: 2365 EELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2422
Query: 214 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQQKCQQQ 271
+ A +E L +Q+ A ++ +E+ + +E L A A+ QQ ++ Q+Q
Sbjct: 2423 AAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2479
Query: 272 QQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++ Q KE++ + + Q T E E
Sbjct: 2480 ARRLQEDKEQMAQQLAEETQGFQRTLEAE 2508
Score = 30.8 bits (68), Expect = 1.7
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 104 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 163
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1365 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1421
Query: 164 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 215
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1422 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1477
Query: 216 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 275
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1478 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1534
Query: 276 QRLKEELEKHGMQVPAQAQSTQEE 299
Q E+ + Q +S QEE
Sbjct: 1535 QEEVVRREEAAVDAQQQKRSIQEE 1558
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 62.0 bits (149), Expect = 7e-10
Identities = 75/265 (28%), Positives = 121/265 (45%), Gaps = 38/265 (14%)
Query: 36 LMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGE 94
L E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E
Sbjct: 2290 LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2349
Query: 95 KVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 154
+ E +S + E L++ + +E R +E +R Q EE K +
Sbjct: 2350 RQRQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRT 2398
Query: 155 RLAFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDV 209
LA +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E++
Sbjct: 2399 ELATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2454
Query: 210 K----HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQ 259
+ QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2455 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----R 2509
Query: 260 RHQQLQQKCQQQQQKRQRLKEELEK 284
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2510 EEQQRQQ--QQMEQERQRLVASMEE 2532
Score = 53.1 bits (126), Expect = 3e-07
Identities = 66/294 (22%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 19 RAEKAGGQDTSSQK-IEDLMEMVQ-KLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE 76
RAE+A Q +Q+ E L VQ + Q+ E + + E + K++A + L E
Sbjct: 1459 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1518
Query: 77 ARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQEC--K 134
R E ++ L E+ ++ + + R Q K + K L+ +
Sbjct: 1519 LRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRASFAEKTAQLERSLQE 1576
Query: 135 ERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQ 194
E ++ L+ E E+ Q+Q A E+ + + + W E L + A E+
Sbjct: 1577 EHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANEALRLRLQA-----EE 1628
Query: 195 LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELL 254
+ +++ L +A E K + G + ++A +L ++E K +L
Sbjct: 1629 VAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQRELAEQELEKQRQLA 1679
Query: 255 AAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEA 301
AQ+ +Q+ +Q +Q+RQ L+EEL + + A Q QE EA
Sbjct: 1680 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1733
Score = 51.6 bits (122), Expect = 9e-07
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 50/278 (17%)
Query: 26 QDTSSQKIEDLMEMVQKLQKVGSLEPR--------VEVLINRINEVQQAKKKANKDLGEA 77
Q+ Q + L E Q Q+ E + E L R+ E+ +A+ +A +D
Sbjct: 2325 QEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF 2384
Query: 78 RTICEALQKELDSLHGEKVHLKEILSKKQETL-RILRLHCQEKESEAHRKHTMLQECKER 136
R E + GEK+H E+ ++++ TL + L + Q+ + +A R + E
Sbjct: 2385 RKQAEEI--------GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAE---- 2432
Query: 137 ISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSS----K 192
+E EK K +Q + + E++ + E+L +E AL S K
Sbjct: 2433 -------LEREKEKLQQEAKLLQLKSEEMQTVQQ--------EQLLQETQALQQSFLSEK 2477
Query: 193 EQLLKEEKLV---KATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEE 246
+ LL+ E+ + KA LE QL A+ +E + Q E V +E
Sbjct: 2478 DSLLQRERFIEQEKAKLE----QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2533
Query: 247 HRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEK 284
R+ E ++ ++LQQ QQ++Q+ + L EE ++
Sbjct: 2534 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2571
Score = 42.7 bits (99), Expect = 4e-04
Identities = 77/316 (24%), Positives = 134/316 (42%), Gaps = 59/316 (18%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKVGS---LEPRVEVLINRIN-EVQQAKKKANKDL 74
R + +D + Q+ E + +KL +G L+ E+ + E ++ ++ A +
Sbjct: 1793 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1852
Query: 75 GEARTICEA--------------LQKELDS-LHGEKVHLKEIL-SKKQETLRILRLHCQE 118
+ R + E L+K DS L +K +++ L ++Q IL L
Sbjct: 1853 FQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1912
Query: 119 KESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDF 175
+++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1913 EKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE------- 1965
Query: 176 HMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRS-- 233
ER+ K + A + + Q KA LE+V+ + ++E LR
Sbjct: 1966 ---ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEARRLRERA 2006
Query: 234 -QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKEELE--KH 285
QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+ E E +
Sbjct: 2007 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2066
Query: 286 GMQVPAQAQSTQEEEA 301
+ +A+ E EA
Sbjct: 2067 AAEEAEEARVQAEREA 2082
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/293 (19%), Positives = 132/293 (45%), Gaps = 51/293 (17%)
Query: 8 SKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAK 67
++ EP A + + G ++ Q+ DL +L + S ++ + + +++ +
Sbjct: 1269 AQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTS--QYIKFISETLRRMEEEE 1326
Query: 68 KKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKH 127
+ A + E E+ L E+ + ++ ++ H Q K ++A R+
Sbjct: 1327 RLAEQQRAE-----------------ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE- 1367
Query: 128 TMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICA 187
+E ++R+ ++ EE +Q + + +E+L+ L + + A++ A
Sbjct: 1368 --AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEA-----EIQAKARQAEA 1420
Query: 188 LDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEH 247
+ S+ ++ +E ++V+ LE + Q GAEG + L R++EA A + QEE
Sbjct: 1421 AERSRLRIEEEIRVVRLQLEATERQRG---GAEGEL---QALRARAEEAEAQKRQAQEE- 1473
Query: 248 RKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++L+++ Q + Q++++ + EL +V A+A++ +E++
Sbjct: 1474 -------------AERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAAREKQ 1510
Score = 40.0 bits (92), Expect = 0.003
Identities = 62/262 (23%), Positives = 109/262 (41%), Gaps = 26/262 (9%)
Query: 34 EDLMEMVQKLQKVGSLEPRVEVLINRI--NEVQQAKKKANKDLGEARTICEALQKELDSL 91
E+++ + +K + + +E+ + RI N + K +L AR A ++E
Sbjct: 1903 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1962
Query: 92 HGEKVHLKEILSKKQETLRILRLHCQEKE------SEAHRKHTMLQECKERISALNLQIE 145
E+ +++ L+ ++E R + +E E EA R L+E E+ SA LQ+
Sbjct: 1963 EAEE-RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARR----LRERAEQESARQLQLA 2017
Query: 146 EEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKAT 205
+E Q RL EE+ Q K+ + + L +E LD QL E + +
Sbjct: 2018 QEA---AQKRLQAEEKAHAFAVQQKEQ---ELQQTLQQEQSVLD----QLRGEAEAARRA 2067
Query: 206 LEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQ 263
E+ + A+ ++E L+ Q A Q + AE+L A Q +
Sbjct: 2068 AEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2126
Query: 264 LQQKCQQQQQKRQRLKEELEKH 285
Q Q +++Q E+EKH
Sbjct: 2127 RAQAEQAALRQKQAADAEMEKH 2148
Score = 40.0 bits (92), Expect = 0.003
Identities = 70/329 (21%), Positives = 136/329 (41%), Gaps = 52/329 (15%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKKKANKDLGEA 77
+AE+ QK ++L + +Q+ Q V L E E ++A+ +A ++ ++
Sbjct: 2026 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2085
Query: 78 RTICEALQK------ELDSLHGEKVHLKEILSKKQETLRILRLHCQEK----------ES 121
R E ++ E + E L K+ E R ++ E
Sbjct: 2086 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2145
Query: 122 EAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL-----------------RLAFE 159
E H+K T+ Q+ + + ++ L LQ+EE +++ L R E
Sbjct: 2146 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2205
Query: 160 EQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLEDVKHQL 213
E+L + Q ++L + R+ E AL D+++ L +E EK+ + E + +
Sbjct: 2206 EELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2263
Query: 214 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQQKCQQQ 271
+ A +E L +Q+ A ++ +E+ + +E L A A+ QQ ++ Q+Q
Sbjct: 2264 AAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2320
Query: 272 QQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++ Q KE++ + + Q T E E
Sbjct: 2321 ARRLQEDKEQMAQQLAEETQGFQRTLEAE 2349
Score = 30.8 bits (68), Expect = 1.7
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 104 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 163
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1206 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1262
Query: 164 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 215
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1263 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1318
Query: 216 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 275
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1319 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1375
Query: 276 QRLKEELEKHGMQVPAQAQSTQEE 299
Q E+ + Q +S QEE
Sbjct: 1376 QEEVVRREEAAVDAQQQKRSIQEE 1399
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 62.0 bits (149), Expect = 7e-10
Identities = 75/265 (28%), Positives = 121/265 (45%), Gaps = 38/265 (14%)
Query: 36 LMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGE 94
L E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E
Sbjct: 2298 LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2357
Query: 95 KVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 154
+ E +S + E L++ + +E R +E +R Q EE K +
Sbjct: 2358 RQRQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRT 2406
Query: 155 RLAFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDV 209
LA +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E++
Sbjct: 2407 ELATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2462
Query: 210 K----HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQ 259
+ QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2463 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----R 2517
Query: 260 RHQQLQQKCQQQQQKRQRLKEELEK 284
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2518 EEQQRQQ--QQMEQERQRLVASMEE 2540
Score = 53.1 bits (126), Expect = 3e-07
Identities = 66/294 (22%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 19 RAEKAGGQDTSSQK-IEDLMEMVQ-KLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE 76
RAE+A Q +Q+ E L VQ + Q+ E + + E + K++A + L E
Sbjct: 1467 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1526
Query: 77 ARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQEC--K 134
R E ++ L E+ ++ + + R Q K + K L+ +
Sbjct: 1527 LRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRASFAEKTAQLERSLQE 1584
Query: 135 ERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQ 194
E ++ L+ E E+ Q+Q A E+ + + + W E L + A E+
Sbjct: 1585 EHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANEALRLRLQA-----EE 1636
Query: 195 LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELL 254
+ +++ L +A E K + G + ++A +L ++E K +L
Sbjct: 1637 VAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQRELAEQELEKQRQLA 1687
Query: 255 AAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEA 301
AQ+ +Q+ +Q +Q+RQ L+EEL + + A Q QE EA
Sbjct: 1688 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1741
Score = 51.6 bits (122), Expect = 9e-07
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 50/278 (17%)
Query: 26 QDTSSQKIEDLMEMVQKLQKVGSLEPR--------VEVLINRINEVQQAKKKANKDLGEA 77
Q+ Q + L E Q Q+ E + E L R+ E+ +A+ +A +D
Sbjct: 2333 QEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF 2392
Query: 78 RTICEALQKELDSLHGEKVHLKEILSKKQETL-RILRLHCQEKESEAHRKHTMLQECKER 136
R E + GEK+H E+ ++++ TL + L + Q+ + +A R + E
Sbjct: 2393 RKQAEEI--------GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAE---- 2440
Query: 137 ISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSS----K 192
+E EK K +Q + + E++ + E+L +E AL S K
Sbjct: 2441 -------LEREKEKLQQEAKLLQLKSEEMQTVQQ--------EQLLQETQALQQSFLSEK 2485
Query: 193 EQLLKEEKLV---KATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEE 246
+ LL+ E+ + KA LE QL A+ +E + Q E V +E
Sbjct: 2486 DSLLQRERFIEQEKAKLE----QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2541
Query: 247 HRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEK 284
R+ E ++ ++LQQ QQ++Q+ + L EE ++
Sbjct: 2542 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2579
Score = 42.7 bits (99), Expect = 4e-04
Identities = 77/316 (24%), Positives = 134/316 (42%), Gaps = 59/316 (18%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKVGS---LEPRVEVLINRIN-EVQQAKKKANKDL 74
R + +D + Q+ E + +KL +G L+ E+ + E ++ ++ A +
Sbjct: 1801 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1860
Query: 75 GEARTICEA--------------LQKELDS-LHGEKVHLKEIL-SKKQETLRILRLHCQE 118
+ R + E L+K DS L +K +++ L ++Q IL L
Sbjct: 1861 FQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1920
Query: 119 KESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDF 175
+++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1921 EKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE------- 1973
Query: 176 HMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRS-- 233
ER+ K + A + + Q KA LE+V+ + ++E LR
Sbjct: 1974 ---ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEARRLRERA 2014
Query: 234 -QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKEELE--KH 285
QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+ E E +
Sbjct: 2015 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2074
Query: 286 GMQVPAQAQSTQEEEA 301
+ +A+ E EA
Sbjct: 2075 AAEEAEEARVQAEREA 2090
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/293 (19%), Positives = 132/293 (45%), Gaps = 51/293 (17%)
Query: 8 SKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAK 67
++ EP A + + G ++ Q+ DL +L + S ++ + + +++ +
Sbjct: 1277 AQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTS--QYIKFISETLRRMEEEE 1334
Query: 68 KKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKH 127
+ A + E E+ L E+ + ++ ++ H Q K ++A R+
Sbjct: 1335 RLAEQQRAE-----------------ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE- 1375
Query: 128 TMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICA 187
+E ++R+ ++ EE +Q + + +E+L+ L + + A++ A
Sbjct: 1376 --AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEA-----EIQAKARQAEA 1428
Query: 188 LDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEH 247
+ S+ ++ +E ++V+ LE + Q GAEG + L R++EA A + QEE
Sbjct: 1429 AERSRLRIEEEIRVVRLQLEATERQRG---GAEGEL---QALRARAEEAEAQKRQAQEE- 1481
Query: 248 RKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++L+++ Q + Q++++ + EL +V A+A++ +E++
Sbjct: 1482 -------------AERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAAREKQ 1518
Score = 40.0 bits (92), Expect = 0.003
Identities = 62/262 (23%), Positives = 109/262 (41%), Gaps = 26/262 (9%)
Query: 34 EDLMEMVQKLQKVGSLEPRVEVLINRI--NEVQQAKKKANKDLGEARTICEALQKELDSL 91
E+++ + +K + + +E+ + RI N + K +L AR A ++E
Sbjct: 1911 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1970
Query: 92 HGEKVHLKEILSKKQETLRILRLHCQEKE------SEAHRKHTMLQECKERISALNLQIE 145
E+ +++ L+ ++E R + +E E EA R L+E E+ SA LQ+
Sbjct: 1971 EAEE-RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARR----LRERAEQESARQLQLA 2025
Query: 146 EEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKAT 205
+E Q RL EE+ Q K+ + + L +E LD QL E + +
Sbjct: 2026 QEA---AQKRLQAEEKAHAFAVQQKEQ---ELQQTLQQEQSVLD----QLRGEAEAARRA 2075
Query: 206 LEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQ 263
E+ + A+ ++E L+ Q A Q + AE+L A Q +
Sbjct: 2076 AEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2134
Query: 264 LQQKCQQQQQKRQRLKEELEKH 285
Q Q +++Q E+EKH
Sbjct: 2135 RAQAEQAALRQKQAADAEMEKH 2156
Score = 40.0 bits (92), Expect = 0.003
Identities = 70/329 (21%), Positives = 136/329 (41%), Gaps = 52/329 (15%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKKKANKDLGEA 77
+AE+ QK ++L + +Q+ Q V L E E ++A+ +A ++ ++
Sbjct: 2034 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2093
Query: 78 RTICEALQK------ELDSLHGEKVHLKEILSKKQETLRILRLHCQEK----------ES 121
R E ++ E + E L K+ E R ++ E
Sbjct: 2094 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2153
Query: 122 EAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL-----------------RLAFE 159
E H+K T+ Q+ + + ++ L LQ+EE +++ L R E
Sbjct: 2154 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2213
Query: 160 EQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLEDVKHQL 213
E+L + Q ++L + R+ E AL D+++ L +E EK+ + E + +
Sbjct: 2214 EELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2271
Query: 214 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQQKCQQQ 271
+ A +E L +Q+ A ++ +E+ + +E L A A+ QQ ++ Q+Q
Sbjct: 2272 AAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2328
Query: 272 QQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++ Q KE++ + + Q T E E
Sbjct: 2329 ARRLQEDKEQMAQQLAEETQGFQRTLEAE 2357
Score = 30.8 bits (68), Expect = 1.7
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 104 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 163
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1214 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1270
Query: 164 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 215
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1271 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1326
Query: 216 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 275
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1327 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1383
Query: 276 QRLKEELEKHGMQVPAQAQSTQEE 299
Q E+ + Q +S QEE
Sbjct: 1384 QEEVVRREEAAVDAQQQKRSIQEE 1407
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 62.0 bits (149), Expect = 7e-10
Identities = 75/265 (28%), Positives = 121/265 (45%), Gaps = 38/265 (14%)
Query: 36 LMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGE 94
L E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E
Sbjct: 2339 LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2398
Query: 95 KVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 154
+ E +S + E L++ + +E R +E +R Q EE K +
Sbjct: 2399 RQRQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRT 2447
Query: 155 RLAFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDV 209
LA +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E++
Sbjct: 2448 ELATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2503
Query: 210 K----HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQ 259
+ QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2504 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----R 2558
Query: 260 RHQQLQQKCQQQQQKRQRLKEELEK 284
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2559 EEQQRQQ--QQMEQERQRLVASMEE 2581
Score = 53.1 bits (126), Expect = 3e-07
Identities = 66/294 (22%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 19 RAEKAGGQDTSSQK-IEDLMEMVQ-KLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE 76
RAE+A Q +Q+ E L VQ + Q+ E + + E + K++A + L E
Sbjct: 1508 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1567
Query: 77 ARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQEC--K 134
R E ++ L E+ ++ + + R Q K + K L+ +
Sbjct: 1568 LRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRASFAEKTAQLERSLQE 1625
Query: 135 ERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQ 194
E ++ L+ E E+ Q+Q A E+ + + + W E L + A E+
Sbjct: 1626 EHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANEALRLRLQA-----EE 1677
Query: 195 LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELL 254
+ +++ L +A E K + G + ++A +L ++E K +L
Sbjct: 1678 VAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQRELAEQELEKQRQLA 1728
Query: 255 AAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEA 301
AQ+ +Q+ +Q +Q+RQ L+EEL + + A Q QE EA
Sbjct: 1729 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1782
Score = 51.6 bits (122), Expect = 9e-07
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 50/278 (17%)
Query: 26 QDTSSQKIEDLMEMVQKLQKVGSLEPR--------VEVLINRINEVQQAKKKANKDLGEA 77
Q+ Q + L E Q Q+ E + E L R+ E+ +A+ +A +D
Sbjct: 2374 QEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF 2433
Query: 78 RTICEALQKELDSLHGEKVHLKEILSKKQETL-RILRLHCQEKESEAHRKHTMLQECKER 136
R E + GEK+H E+ ++++ TL + L + Q+ + +A R + E
Sbjct: 2434 RKQAEEI--------GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAE---- 2481
Query: 137 ISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSS----K 192
+E EK K +Q + + E++ + E+L +E AL S K
Sbjct: 2482 -------LEREKEKLQQEAKLLQLKSEEMQTVQQ--------EQLLQETQALQQSFLSEK 2526
Query: 193 EQLLKEEKLV---KATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEE 246
+ LL+ E+ + KA LE QL A+ +E + Q E V +E
Sbjct: 2527 DSLLQRERFIEQEKAKLE----QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2582
Query: 247 HRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEK 284
R+ E ++ ++LQQ QQ++Q+ + L EE ++
Sbjct: 2583 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2620
Score = 42.7 bits (99), Expect = 4e-04
Identities = 77/316 (24%), Positives = 134/316 (42%), Gaps = 59/316 (18%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKVGS---LEPRVEVLINRIN-EVQQAKKKANKDL 74
R + +D + Q+ E + +KL +G L+ E+ + E ++ ++ A +
Sbjct: 1842 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1901
Query: 75 GEARTICEA--------------LQKELDS-LHGEKVHLKEIL-SKKQETLRILRLHCQE 118
+ R + E L+K DS L +K +++ L ++Q IL L
Sbjct: 1902 FQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1961
Query: 119 KESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDF 175
+++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1962 EKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE------- 2014
Query: 176 HMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRS-- 233
ER+ K + A + + Q KA LE+V+ + ++E LR
Sbjct: 2015 ---ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEARRLRERA 2055
Query: 234 -QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKEELE--KH 285
QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+ E E +
Sbjct: 2056 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2115
Query: 286 GMQVPAQAQSTQEEEA 301
+ +A+ E EA
Sbjct: 2116 AAEEAEEARVQAEREA 2131
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/293 (19%), Positives = 132/293 (45%), Gaps = 51/293 (17%)
Query: 8 SKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAK 67
++ EP A + + G ++ Q+ DL +L + S ++ + + +++ +
Sbjct: 1318 AQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTS--QYIKFISETLRRMEEEE 1375
Query: 68 KKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKH 127
+ A + E E+ L E+ + ++ ++ H Q K ++A R+
Sbjct: 1376 RLAEQQRAE-----------------ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE- 1416
Query: 128 TMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICA 187
+E ++R+ ++ EE +Q + + +E+L+ L + + A++ A
Sbjct: 1417 --AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEA-----EIQAKARQAEA 1469
Query: 188 LDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEH 247
+ S+ ++ +E ++V+ LE + Q GAEG + L R++EA A + QEE
Sbjct: 1470 AERSRLRIEEEIRVVRLQLEATERQRG---GAEGEL---QALRARAEEAEAQKRQAQEE- 1522
Query: 248 RKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++L+++ Q + Q++++ + EL +V A+A++ +E++
Sbjct: 1523 -------------AERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAAREKQ 1559
Score = 40.0 bits (92), Expect = 0.003
Identities = 62/262 (23%), Positives = 109/262 (41%), Gaps = 26/262 (9%)
Query: 34 EDLMEMVQKLQKVGSLEPRVEVLINRI--NEVQQAKKKANKDLGEARTICEALQKELDSL 91
E+++ + +K + + +E+ + RI N + K +L AR A ++E
Sbjct: 1952 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 2011
Query: 92 HGEKVHLKEILSKKQETLRILRLHCQEKE------SEAHRKHTMLQECKERISALNLQIE 145
E+ +++ L+ ++E R + +E E EA R L+E E+ SA LQ+
Sbjct: 2012 EAEE-RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARR----LRERAEQESARQLQLA 2066
Query: 146 EEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKAT 205
+E Q RL EE+ Q K+ + + L +E LD QL E + +
Sbjct: 2067 QEA---AQKRLQAEEKAHAFAVQQKEQ---ELQQTLQQEQSVLD----QLRGEAEAARRA 2116
Query: 206 LEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQ 263
E+ + A+ ++E L+ Q A Q + AE+L A Q +
Sbjct: 2117 AEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2175
Query: 264 LQQKCQQQQQKRQRLKEELEKH 285
Q Q +++Q E+EKH
Sbjct: 2176 RAQAEQAALRQKQAADAEMEKH 2197
Score = 40.0 bits (92), Expect = 0.003
Identities = 70/329 (21%), Positives = 136/329 (41%), Gaps = 52/329 (15%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKKKANKDLGEA 77
+AE+ QK ++L + +Q+ Q V L E E ++A+ +A ++ ++
Sbjct: 2075 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2134
Query: 78 RTICEALQK------ELDSLHGEKVHLKEILSKKQETLRILRLHCQEK----------ES 121
R E ++ E + E L K+ E R ++ E
Sbjct: 2135 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2194
Query: 122 EAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL-----------------RLAFE 159
E H+K T+ Q+ + + ++ L LQ+EE +++ L R E
Sbjct: 2195 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2254
Query: 160 EQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLEDVKHQL 213
E+L + Q ++L + R+ E AL D+++ L +E EK+ + E + +
Sbjct: 2255 EELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2312
Query: 214 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQQKCQQQ 271
+ A +E L +Q+ A ++ +E+ + +E L A A+ QQ ++ Q+Q
Sbjct: 2313 AAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2369
Query: 272 QQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++ Q KE++ + + Q T E E
Sbjct: 2370 ARRLQEDKEQMAQQLAEETQGFQRTLEAE 2398
Score = 30.8 bits (68), Expect = 1.7
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 104 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 163
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1255 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1311
Query: 164 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 215
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1312 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1367
Query: 216 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 275
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1368 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1424
Query: 276 QRLKEELEKHGMQVPAQAQSTQEE 299
Q E+ + Q +S QEE
Sbjct: 1425 QEEVVRREEAAVDAQQQKRSIQEE 1448
>gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 2 [Homo sapiens]
Length = 601
Score = 60.8 bits (146), Expect = 1e-09
Identities = 70/339 (20%), Positives = 135/339 (39%), Gaps = 69/339 (20%)
Query: 37 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 96
+E+ Q + SL+ + + + +++ E ++A K K + L + + L+ +
Sbjct: 90 VEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLY 149
Query: 97 HLKEIL---SKKQETLRILRLHCQEKESEAH-----------------------RKHTML 130
H+K L +K + L + H +++ E R L
Sbjct: 150 HMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKL 209
Query: 131 QECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDS 190
++ + L +Q+ + K +Q++L +E E L G+ + W M ++++EIC L
Sbjct: 210 EQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGE-RARWQQRM-RKMSQEICTLKK 267
Query: 191 SKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDE----------------------- 227
K+Q ++ + ++ +L +K+Q+ E P+ E
Sbjct: 268 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKK 327
Query: 228 --GLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ------------- 272
+ L +Q +Q +E RK EE + ++H+ LQQ + Q
Sbjct: 328 NQRISLLNQRQEERIQEQEERLRKQEERIQ---EQHKSLQQLAKPQSVFEEPNNENKNAL 384
Query: 273 QKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPG 311
Q Q++KE EK G + + +E EA G AP PG
Sbjct: 385 QLEQQVKELQEKLGEVKETETSAQKEPEAARGPGAPGPG 423
>gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 630
Score = 60.8 bits (146), Expect = 1e-09
Identities = 67/312 (21%), Positives = 132/312 (42%), Gaps = 53/312 (16%)
Query: 28 TSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKK----------KANKDLGE 76
TSS ++DL Q+ V S + L N I ++Q KK KAN +
Sbjct: 67 TSSATLKDLESPCQERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQK 126
Query: 77 ARTICEA----LQKELDSLHGEKVHLKEIL---SKKQETLRILRLHCQEKESEAH----- 124
A+ + E L + + L+ + H+K L +K + L + H +++ E
Sbjct: 127 AKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSN 186
Query: 125 ------------------RKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLM 166
R L++ + L +Q+ + K +Q++L +E E L
Sbjct: 187 VMATQKKKANQLSSRSKARTEWKLEQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLK 246
Query: 167 GQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLD 226
G+ + W M ++++EIC L K+Q ++ + ++ +L +K+Q+ E P+
Sbjct: 247 GE-RARWQQRM-RKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPS 304
Query: 227 EGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHG 286
E +Q ++E + L A +++Q++ Q+Q+++ Q +E L K
Sbjct: 305 E----------VELQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQE 354
Query: 287 MQVPAQAQSTQE 298
++ Q +S Q+
Sbjct: 355 ERIQEQHKSLQQ 366
>gi|51317366 myosin XVIIIB [Homo sapiens]
Length = 2567
Score = 60.1 bits (144), Expect = 3e-09
Identities = 70/323 (21%), Positives = 144/323 (44%), Gaps = 74/323 (22%)
Query: 38 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVH 97
++ QK Q+ L+ +VE+L + E+ + LGE L++ L L +
Sbjct: 1647 QLKQKEQEASQLKQQVEMLQDHKRELL-----GSPSLGE--NCVAGLKERLWKLESSALE 1699
Query: 98 LKEILSKKQETL---------------RILRLHCQEKESEAHRKHTMLQECKERISALNL 142
++I S+++ T+ R+ ++H +++E + + Q C++R+ L +
Sbjct: 1700 QQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEM 1759
Query: 143 QIEEEKNKQRQLRLAFEEQLEDLMGQHKDLW---DFHMPERLAKEICALDS--------- 190
Q+E+E +++Q+ L ++ LE L+G D DF + +RL +++ +
Sbjct: 1760 QLEQEY-EEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLL 1818
Query: 191 ----------SKEQL-----------------LKEEKLVKATLEDVKHQLCSLCGAEGPS 223
SKE+L LK +K++ A LE + +L ++ S
Sbjct: 1819 GTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENM--TRNKS 1876
Query: 224 TLDEGLFLRSQEAAATVQLFQEEHRKAEELL----------AAAAQRHQQLQQKCQQQQQ 273
+DE L+ E A ++ E+ EL+ AA + Q+LQ + ++ ++
Sbjct: 1877 LVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKK 1936
Query: 274 KRQRLKEELEKHGMQVPAQAQST 296
++ +L+E+L+ M++ QST
Sbjct: 1937 EKHKLQEQLQVAQMRIEYLEQST 1959
Score = 40.8 bits (94), Expect = 0.002
Identities = 49/234 (20%), Positives = 97/234 (41%), Gaps = 22/234 (9%)
Query: 60 INEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEK 119
+ ++QQ K+ ++ + + E LQ L G + ++ +E L L E+
Sbjct: 1641 LGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQ 1700
Query: 120 ESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE 179
+ ++ +++ ++ L+IE K ++ R EE+LED+ +
Sbjct: 1701 QKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVR------------Q 1748
Query: 180 RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFL-----RSQ 234
K + L+ EQ +E+++V +D++ + +LC G D L R+
Sbjct: 1749 SCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTH 1808
Query: 235 EAAATVQLF--QEEHRKAEELLAAAAQRHQQLQQ---KCQQQQQKRQRLKEELE 283
+ VQL E K + H QL+Q KC++ + ++ L +LE
Sbjct: 1809 ALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLE 1862
Score = 33.9 bits (76), Expect = 0.20
Identities = 55/255 (21%), Positives = 107/255 (41%), Gaps = 21/255 (8%)
Query: 49 LEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQET 108
L R++ R++ A+K+ + LGE ++ + +K L + HL L E
Sbjct: 1532 LRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDL----ED 1587
Query: 109 LRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEE--KNKQRQLRLAFEEQLEDLM 166
+L + Q + E +K + AL + E+ + K Q + +L L
Sbjct: 1588 TCVLLENQQSRNHELEKKQKKFD--LQLAQALGESVFEKGLREKVTQENTSVRWELGQLQ 1645
Query: 167 GQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLD 226
Q K +L +++ L K +LL L + + +K +L L S+
Sbjct: 1646 QQLKQ--KEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKL-----ESSAL 1698
Query: 227 EGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQ-QQQKRQRLKEELEKH 285
E ++SQ+ QL Q R E+ +R +Q+ QK ++ Q+++ + +++ +K
Sbjct: 1699 EQQKIQSQQENTIKQLEQLRQRFELEI-----ERMKQMHQKDREDQEEELEDVRQSCQKR 1753
Query: 286 GMQVPAQAQSTQEEE 300
Q+ Q + EE+
Sbjct: 1754 LHQLEMQLEQEYEEK 1768
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 60.1 bits (144), Expect = 3e-09
Identities = 66/268 (24%), Positives = 125/268 (46%), Gaps = 18/268 (6%)
Query: 27 DTSSQKIEDLMEMVQKLQ-KVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQ 85
D +SQ +E L E+++K ++ ++ R+ L +R+ EV+Q + A KDL + + Q
Sbjct: 265 DETSQIVE-LQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQ 323
Query: 86 KELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIE 145
+++ E + KE + ++ TL L Q + + H + L+ A+ Q+
Sbjct: 324 RDI----REAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQM- 378
Query: 146 EEKNKQRQLRLAFEEQ-LEDLMGQHKDLWDFHMPERLAKEICALDSSKEQ---LLKEEKL 201
EEKN+Q Q RL EQ L+ M + + L + + LA+ I AL ++E+ + + +
Sbjct: 379 EEKNRQLQERLELAEQKLQQTMRKAETLPE--VEAELAQRIAALTKAEERHGNIEERMRH 436
Query: 202 VKATLEDVKHQL-----CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAA 256
++ LE+ +L E L + + E+ +QL +E A E
Sbjct: 437 LEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNV 496
Query: 257 AAQRHQQLQQKCQQQQQKRQRLKEELEK 284
Q + ++ ++ ++RL EE+EK
Sbjct: 497 LIQESETFRKNLEESLHDKERLAEEIEK 524
Score = 37.0 bits (84), Expect = 0.023
Identities = 50/196 (25%), Positives = 93/196 (47%), Gaps = 19/196 (9%)
Query: 26 QDTSSQKIEDLME--MVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEA 83
+ TS + D +E + K + +E + L R+ + A++K + + +A T+ E
Sbjct: 353 ESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERL---ELAEQKLQQTMRKAETLPE- 408
Query: 84 LQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESE---AHRKHTMLQECKERISAL 140
++ EL +E +E +R L +EK E A ++ M +E +R+S
Sbjct: 409 VEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDT 468
Query: 141 NLQIEEEKNKQRQLRL-----AFEEQ---LEDLMGQHKDLWD-FHMPERLAKEICALDSS 191
++ E N++ QL L A EE+ +++ K+L + H ERLA+EI L S
Sbjct: 469 VDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSE 528
Query: 192 KEQL-LKEEKLVKATL 206
+QL ++ L++ T+
Sbjct: 529 LDQLKMRTGSLIEPTI 544
>gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 [Homo sapiens]
Length = 602
Score = 59.7 bits (143), Expect = 3e-09
Identities = 70/339 (20%), Positives = 134/339 (39%), Gaps = 69/339 (20%)
Query: 37 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 96
+E+ Q + SL+ + + + +++ E ++A K K + L + L+ +
Sbjct: 90 VEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKGKLNTDLY 149
Query: 97 HLKEIL---SKKQETLRILRLHCQEKESEAH-----------------------RKHTML 130
H+K L +K + L + H +++ E R L
Sbjct: 150 HMKRSLRYFEEKSKDLAVCLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKL 209
Query: 131 QECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDS 190
++ + L +Q+ + K +Q++L +E E L G+ + W M ++++EIC L
Sbjct: 210 EQSMREEALLKVQLTQLKESFQQVQLERDECAEHLKGE-RARWQQRM-RKMSQEICTLKK 267
Query: 191 SKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDE----------------------- 227
K+Q ++ + ++ +L +K+Q+ E P+ E
Sbjct: 268 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKK 327
Query: 228 --GLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ------------- 272
+ L +Q +Q +E RK EE + ++H+ LQQ + Q
Sbjct: 328 NQRISLLNQRQEERIQEQEERLRKQEERIQ---EQHKSLQQLAKPQSVFEEPNNENKNAL 384
Query: 273 QKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPG 311
Q Q++KE EK G + + +E EA G AP PG
Sbjct: 385 QLEQQVKELQEKLGEVKETETSAQKEPEAARGPGAPGPG 423
>gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 632
Score = 59.7 bits (143), Expect = 3e-09
Identities = 67/312 (21%), Positives = 132/312 (42%), Gaps = 53/312 (16%)
Query: 28 TSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKK----------KANKDLGE 76
TSS ++DL Q+ V S + L N I ++Q KK KAN +
Sbjct: 67 TSSATLKDLESPCQERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQK 126
Query: 77 ARTICEALQKELD----SLHGEKVHLKEIL---SKKQETLRILRLHCQEKESEAH----- 124
A+ + E + L+ L+ + H+K L +K + L + H +++ E
Sbjct: 127 AKRVLEVQIQTLNIQKGKLNTDLYHMKRSLRYFEEKSKDLAVCLQHSLQRKGELESVLSN 186
Query: 125 ------------------RKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLM 166
R L++ + L +Q+ + K +Q++L +E E L
Sbjct: 187 VMATQKKKANQLSSRSKARTEWKLEQSMREEALLKVQLTQLKESFQQVQLERDECAEHLK 246
Query: 167 GQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLD 226
G+ + W M ++++EIC L K+Q ++ + ++ +L +K+Q+ E P+
Sbjct: 247 GE-RARWQQRM-RKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPS 304
Query: 227 EGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHG 286
E +Q ++E + L A +++Q++ Q+Q+++ Q +E L K
Sbjct: 305 E----------VELQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQE 354
Query: 287 MQVPAQAQSTQE 298
++ Q +S Q+
Sbjct: 355 ERIQEQHKSLQQ 366
>gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein 3
isoform 2 [Homo sapiens]
Length = 602
Score = 59.7 bits (143), Expect = 3e-09
Identities = 70/336 (20%), Positives = 133/336 (39%), Gaps = 63/336 (18%)
Query: 37 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 96
+E+ Q + SL+ + + + +++ E ++A K K + L + + L+ +
Sbjct: 90 VEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLY 149
Query: 97 HLKEIL---SKKQETLRILRLHCQEKESEAH-----------------------RKHTML 130
H+K L +K + L + H +++ E R L
Sbjct: 150 HMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKL 209
Query: 131 QECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDS 190
++ + L +Q+ + K +Q++L +E E L G+ + W M ++++EIC L
Sbjct: 210 EQSMREEALLKVQLTQFKESFQQVQLERDEYSEHLKGE-RARWQQRM-RKMSQEICTLKK 267
Query: 191 SKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDE------------------GLFLR 232
K+Q ++ + ++ +L +K+Q+ E P+ E
Sbjct: 268 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKN 327
Query: 233 SQEAAATVQLFQEEHRKAEELLAAAAQR----HQQLQQKCQQQQ-------------QKR 275
+Q + Q +E R+ EE L +R H+ LQQ + Q Q
Sbjct: 328 NQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFKEPNNENKNALQLE 387
Query: 276 QRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPG 311
Q++KE EK G + + +E EA G AP PG
Sbjct: 388 QQVKELQEKLGEVKETETSAQKEPEAARGPGAPGPG 423
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 59.7 bits (143), Expect = 3e-09
Identities = 85/333 (25%), Positives = 145/333 (43%), Gaps = 50/333 (15%)
Query: 4 RSLTSKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQK--VGSLEPRVEVLINRIN 61
R + + + A +++E+A + ++ L E ++ +K V +LE + R+
Sbjct: 719 RQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLC 778
Query: 62 EVQQAKKKA-----NKDLGEARTICEA-LQKELDSLHGEKVHLKE--ILSKKQETLRILR 113
+AK + K + EA+ EA LQK L + +VH K + + E +LR
Sbjct: 779 SSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVE-HRVHQKSYHVAGYEHELSSLLR 837
Query: 114 LHCQEKESEAHRKHTMLQECKERISA-LNLQIEEEKNKQR------------QLRLAFEE 160
QE E E R+ ++E +++ A Q E E+ KQR +L+ A E
Sbjct: 838 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER 897
Query: 161 QLEDL-MGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKL-VKATLEDVKHQLCSL-- 216
+LE + QHK L D R +E+ L++ +L ++ +DVK +L L
Sbjct: 898 ELETVRQEQHKRLEDLRRRHR----------EQERKLQDLELDLETRAKDVKARLALLEV 947
Query: 217 ----CGAEGPSTLD--EGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQ---- 266
E LD + L+S+EA AT Q +E ++ LL + Q + L +
Sbjct: 948 QEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQAR 1007
Query: 267 --KCQQQQQKRQRLKEELEKHGMQVPAQAQSTQ 297
K + Q Q ++L+KH + A+AQ Q
Sbjct: 1008 KLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQ 1040
Score = 50.1 bits (118), Expect = 3e-06
Identities = 44/190 (23%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Query: 99 KEILSKKQETLRILRLH-CQEKESEAHRKHTMLQECKERISALNLQIEEE-KNKQRQLRL 156
+ +L KQE ++ LR CQE+E E R H Q+ ++ +S+L ++++ + ++ ++R
Sbjct: 608 RHLLESKQEKMQQLREKLCQEEEEEILRLH---QQKEQSLSSLRERLQKAIEEEEARMRE 664
Query: 157 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL 216
++L L Q + + A++ +L +E+L ++K +A+LE Q+
Sbjct: 665 EESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQ 724
Query: 217 CGAE-GPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQ-QLQQKCQQQQQK 274
E S E L + + A QL ++ + +E +A + H +L++ C + K
Sbjct: 725 LKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAK 784
Query: 275 RQRLKEELEK 284
+ + L+K
Sbjct: 785 HREVVSSLQK 794
Score = 36.6 bits (83), Expect = 0.030
Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 6/104 (5%)
Query: 198 EEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAA 257
EEK+ + V ++ S P L E +EA A Q+ +++ R LL +
Sbjct: 560 EEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVA--QVLEQDQR---HLLESK 614
Query: 258 AQRHQQLQQK-CQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
++ QQL++K CQ+++++ RL ++ E+ + + Q EEE
Sbjct: 615 QEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEE 658
Score = 33.9 bits (76), Expect = 0.20
Identities = 71/331 (21%), Positives = 141/331 (42%), Gaps = 67/331 (20%)
Query: 15 GAVDRAEKAGGQDTSS------QKIEDLM----EMVQKLQKVG-SLEPRVEVLINRIN-- 61
G ++R ++A ++ + +++EDL E +KLQ + LE R + + R+
Sbjct: 886 GELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALL 945
Query: 62 EVQQ--AKKKANKDLGEARTIC------EALQKELDSLHGEKVHLKEILSKKQETLRILR 113
EVQ+ A+++ + L R + A ++L+ E HL + + +E L L+
Sbjct: 946 EVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQ 1005
Query: 114 LHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLA-------FEEQL--ED 164
+ ES+ Q+ ++ S+L + +++++ R++ + FE L ED
Sbjct: 1006 ARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIED 1065
Query: 165 L---------------MGQHKD------LWDFHMPERLAKEICALDSSKEQLLKE----- 198
L + Q K+ L ++ L+ E AL S+KE L+++
Sbjct: 1066 LRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMR 1125
Query: 199 --EKLVKATLEDVKHQLCSLCG-AEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLA 255
+ +KA + +H+L S A+ P + +R ++E R +E+ +
Sbjct: 1126 RRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKN--------LEKETRHLDEMKS 1177
Query: 256 AAAQRHQQLQQKCQQQQQKRQRLKEELEKHG 286
A + H L++K ++ Q L EE G
Sbjct: 1178 AMRKGHNLLKKKEEKLNQLESSLWEEASDEG 1208
>gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 2 [Homo sapiens]
Length = 602
Score = 59.3 bits (142), Expect = 4e-09
Identities = 81/347 (23%), Positives = 143/347 (41%), Gaps = 59/347 (17%)
Query: 21 EKAGGQDTSSQKIEDLMEMVQKL-QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEART 79
E+A D+ S +I L ++ L Q+ +E ++E N+ Q+AK+ L
Sbjct: 80 ERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQLQTLNI 139
Query: 80 ICEALQKELDSLHGE-----------KVHLKEILSKKQETLRILR--LHCQEKE------ 120
E L +L + V L+ L +K E +L + Q+K+
Sbjct: 140 QKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSDVMATQKKKANQLSS 199
Query: 121 -SEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE 179
S+A + + Q +E + L +Q+ + K +Q++L +E E L G+ + W M
Sbjct: 200 PSKAGTEWKLEQSMREE-ALLKVQLTQLKESFQQVQLERDEYSEHLKGE-RARWQQRM-R 256
Query: 180 RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDE------------ 227
++++EIC L K+Q ++ + ++ +L +K+Q+ E P+ E
Sbjct: 257 KMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER 316
Query: 228 ------GLFLRSQEAAATVQLFQEEHRKAEELLAAAAQR----HQQLQQKCQQQQ----- 272
+Q + Q +E R+ EE L +R H+ LQQ + Q
Sbjct: 317 VAGELQAQVKNNQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFEEP 376
Query: 273 --------QKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPG 311
Q Q++KE EK G ++ + +E EA G AP PG
Sbjct: 377 NNENKSTLQLEQQVKELQEKLGEVKESETSAQKEPEAARGPAAPGPG 423
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 59.3 bits (142), Expect = 4e-09
Identities = 51/260 (19%), Positives = 124/260 (47%), Gaps = 12/260 (4%)
Query: 44 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTIC--EALQKELDSLHGEKVHLKEI 101
+K L+ +++++ + +E+Q K+ + L A+ + + LQ E D L E +
Sbjct: 209 EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 268
Query: 102 LSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQ 161
L + E + Q++E + R+ +QE +E+I +I E++ K R+ E+
Sbjct: 269 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEK 328
Query: 162 LEDLMGQHKDLWDFHMPER-LAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAE 220
E + Q + +W+ R L +++ + +EQ K ++ K ++ + + + +
Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 388
Query: 221 GPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKE 280
++ +R QE ++ QE+ EE + ++ + +++ Q+Q++K +R +E
Sbjct: 389 EEKIREQEEKIREQE-----EMMQEQ----EEKMGEQEEKMWEQEEEMQEQEEKMRRQEE 439
Query: 281 ELEKHGMQVPAQAQSTQEEE 300
++ + ++ Q + +E+E
Sbjct: 440 KIREQEKKIREQEEKIREQE 459
Score = 52.8 bits (125), Expect = 4e-07
Identities = 43/263 (16%), Positives = 118/263 (44%), Gaps = 36/263 (13%)
Query: 38 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVH 97
+M ++ +K+ E +++ +I E ++ ++ + + E E ++++ + + ++
Sbjct: 289 KMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKE---EKMRRQEEMMWEKEEK 345
Query: 98 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLA 157
++E+ K E +I + +E E R+ QE + ++ +I E++ K R+
Sbjct: 346 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEM 405
Query: 158 FEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLC 217
+EQ E + Q + +W+ E + ++ + +E++ ++EK ++ E ++ Q
Sbjct: 406 MQEQEEKMGEQEEKMWE--QEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ----- 458
Query: 218 GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQR 277
+E ++ EE + + + + K Q+Q++K +R
Sbjct: 459 --------------------------EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 278 LKEELEKHGMQVPAQAQSTQEEE 300
+E++ + ++ Q + +E+E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQE 515
Score = 50.4 bits (119), Expect = 2e-06
Identities = 62/295 (21%), Positives = 123/295 (41%), Gaps = 25/295 (8%)
Query: 31 QKIEDLMEMVQKLQKVGSLEPRVEVLINRIN-------EVQQA-------KKKANKDLGE 76
QK E M + V LE LI+R++ E++QA KKKA++ + E
Sbjct: 126 QKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEE 185
Query: 77 ARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKER 136
+AL EL LKE +K QE L+++ E + L+ K
Sbjct: 186 LTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL 245
Query: 137 ISALNLQIEEEK--NKQRQLRLAFEEQLEDLMGQHKDLWDF---HMPERLAKEICALDSS 191
+ LQ E + + + + + Q+E+ +LW+ E++ ++ +
Sbjct: 246 LPQQQLQAEADHLGKELQSVSAKLQAQVEE-----NELWNRLNQQQEEKMWRQEEKIQER 300
Query: 192 KEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAE 251
+E++ ++E+ ++ E ++ Q + E E + +E ++ E K
Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 360
Query: 252 ELLAAAAQRHQ-QLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGD 305
E + + + Q+K Q+Q+ K R +E++ + ++ Q + QE+E G+
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGE 415
Score = 40.8 bits (94), Expect = 0.002
Identities = 38/200 (19%), Positives = 96/200 (48%), Gaps = 18/200 (9%)
Query: 4 RSLTSKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEV 63
R + E A + EK Q+ ++ E++M+ ++ +K+G E E + + E+
Sbjct: 373 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ--EQEEKMGEQE---EKMWEQEEEM 427
Query: 64 QQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEA 123
Q+ ++K + + R + ++++ EK+ +E + ++QE E+E +
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQ-----EEKIREQEEMMQEQEE------KMGEQEGKM 476
Query: 124 HRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAK 183
+ +QE +E++ +I E++ K R+ EQ E + Q + +W+ E++ +
Sbjct: 477 CEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE--QEEKMCE 534
Query: 184 EICALDSSKEQLLKEEKLVK 203
+ + +E++ ++E+ ++
Sbjct: 535 QEEKMQEQEEKMRRQEEKMR 554
Score = 39.7 bits (91), Expect = 0.004
Identities = 42/236 (17%), Positives = 102/236 (43%), Gaps = 28/236 (11%)
Query: 21 EKAGGQDTSSQKIEDLMEMVQKLQKVGSL---EPRVEVLINRINEVQQAKKKANKDLGEA 77
EK Q+ Q+ E + E ++ ++ + E ++ +I E ++ ++ + +GE
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ 416
Query: 78 RTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERI 137
++++ E +E + +++E +R +E+E + + M+QE +E++
Sbjct: 417 -------EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469
Query: 138 SALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLK 197
E++ K + +EQ E + Q E++ ++ + +E++ +
Sbjct: 470 G-------EQEGKMCEQEAKMQEQEEKMRRQE---------EKIREQEKKIREQEEKIRE 513
Query: 198 EEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQE--AAATVQLFQEEHRKAE 251
+E++++ E + Q +C E E R +E V+L Q+E + E
Sbjct: 514 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 58.9 bits (141), Expect = 6e-09
Identities = 75/301 (24%), Positives = 136/301 (45%), Gaps = 43/301 (14%)
Query: 21 EKAGGQDTSSQKIEDLMEMVQKL---------QKVGSLEPRVEVLINRINEVQQAKKKAN 71
EK+ + + KI +L+E Q+ ++ SL+ E R+ +Q K K
Sbjct: 583 EKSNRIEEQNDKISELIERNQRYVEQSNLMMEKRNNSLQTATENTQARVLHAEQEKAKVT 642
Query: 72 KDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQ 131
++L A LQ ++ + ++ L+ L++ + +LR + ++ K + LQ
Sbjct: 643 EELAAATAQVSHLQLKMTAHQKKETELQMQLTESLKETDLLR----GQLTKVQAKLSELQ 698
Query: 132 ECKERISALNLQIEEEKNKQRQLRL---AFEEQLEDLMGQHKDLWDFHMPERLAKEICAL 188
E E+ + + + EK ++QL L + EE+L DL + + L + ++ ER K
Sbjct: 699 ETSEQAQS---KFKSEKQNRKQLELKVTSLEEELTDLRVEKESL-EKNLSERKKK----- 749
Query: 189 DSSKEQLLKEEKL--VKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEE 246
S++E+ EE++ ++ + ++ +L L ST Q AA + L Q E
Sbjct: 750 -SAQERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVST--------DQAAAEQLSLVQAE 800
Query: 247 -----HRKAEELLAAAAQRH-QQLQQKCQQQQQKRQRLKEELEK-HGMQVPAQAQSTQEE 299
K E LLA+A H QQ Q+ C Q+ +Q+L + EK +Q A + Q E
Sbjct: 801 LQTQWEAKCEHLLASAKDEHLQQYQEVCAQRDAYQQKLVQLQEKCLALQAQITALTKQNE 860
Query: 300 E 300
+
Sbjct: 861 Q 861
Score = 39.3 bits (90), Expect = 0.005
Identities = 64/307 (20%), Positives = 123/307 (40%), Gaps = 30/307 (9%)
Query: 28 TSSQKIED--LMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKAN---KDLGEARTICE 82
T+ QK E M++ + L++ L ++ + +++E+Q+ ++A K + R E
Sbjct: 660 TAHQKKETELQMQLTESLKETDLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLE 719
Query: 83 ----ALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHT----MLQEC- 133
+L++EL L EK L++ LS++++ R +E+ E + + L++
Sbjct: 720 LKVTSLEEELTDLRVEKESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDKLRQLL 779
Query: 134 -KERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE------------- 179
K R+S E+ Q +L+ +E + E L+ KD E
Sbjct: 780 KKTRVSTDQAAAEQLSLVQAELQTQWEAKCEHLLASAKDEHLQQYQEVCAQRDAYQQKLV 839
Query: 180 RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAAT 239
+L ++ AL + L K+ + LE K Q+ + A + + +
Sbjct: 840 QLQEKCLALQAQITALTKQNEQHIKELEKNKSQMSGVEAAASDPSEKVKKIMNQVFQSLR 899
Query: 240 VQLFQEEHRKAEELLAAAAQRHQQ--LQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQ 297
+ EE +L + LQ QQ+Q+K + EE E+ + P + Q
Sbjct: 900 REFELEESYNGRTILGTIMNTIKMVTLQLLNQQEQEKEESSSEEEEEKAEERPRRPSQEQ 959
Query: 298 EEEAGPG 304
A G
Sbjct: 960 SASASSG 966
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 58.5 bits (140), Expect = 7e-09
Identities = 52/269 (19%), Positives = 125/269 (46%), Gaps = 27/269 (10%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEAR 78
R ++ ++ Q E +M ++ +++G E +++ ++ E ++ +K + +GE
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 79 TIC----EALQKELDSLHGEKVHLKEILS--KKQETLRILRLHCQEKESEAHRKHTMLQE 132
E +QK+ + + ++ ++E ++QE + + E+E + + ++E
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
Query: 133 CKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSK 192
+E++ Q+ E++ + R+ +Q E + Q + +W+ E++ K+ + +
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE--QKEQMWKQEEQMGEQE 358
Query: 193 EQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEE 252
EQ+ K+E+ V+ E ++ Q +E +R QE Q+ ++E + E+
Sbjct: 359 EQMQKQEEQVRKQEEQMRKQ-------------EEQ--MRKQEE----QMRKQEEQMGEQ 399
Query: 253 LLAAAAQRHQQLQQKCQQQQQKRQRLKEE 281
Q+ Q +Q+ Q +QK Q K+E
Sbjct: 400 KEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
Score = 42.0 bits (97), Expect = 7e-04
Identities = 39/256 (15%), Positives = 110/256 (42%), Gaps = 29/256 (11%)
Query: 62 EVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKES 121
+V++ + + + G+ R + ++ G+ +E + +++E ++ E+E
Sbjct: 172 QVREQEGQVREQEGQVRE----QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 122 EAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLW----DFHM 177
+ ++ + E +E++ Q+++++ + R+ EQ E + Q + +
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287
Query: 178 PERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAA 237
E+ ++ + +EQ+ ++E+ ++ E ++ Q Q
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQ-------------------EEQMGK 328
Query: 238 ATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ--RLKEELEKHGMQVPAQAQS 295
Q+++++ + E+ Q Q +Q+ Q Q+Q+ Q + +E++ K Q+ Q +
Sbjct: 329 QEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388
Query: 296 TQEEEAGPGDVAPRPG 311
+++E G+ + G
Sbjct: 389 MRKQEEQMGEQKEQMG 404
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/172 (19%), Positives = 83/172 (48%), Gaps = 9/172 (5%)
Query: 117 QEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFH 176
+E+E + + ++E + ++ Q+ E++ + + EQ E + Q + + +
Sbjct: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE-- 224
Query: 177 MPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEA 236
E++ K+ + +EQ+ K+E+ V+ E ++ Q + E E L+ +E
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE- 283
Query: 237 AATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQ 288
Q QEE +E ++ +Q++++ +Q +++ ++++E+ E+ G Q
Sbjct: 284 ----QTEQEEQTGEQE--EQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329
Score = 39.3 bits (90), Expect = 0.005
Identities = 46/280 (16%), Positives = 125/280 (44%), Gaps = 16/280 (5%)
Query: 28 TSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKE 87
T+ + E E+ ++LQ V + + +++ I + + K G+ R ++++
Sbjct: 5 TNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQ 64
Query: 88 LDSLHGEKVHLKEILSKKQET---LRILRLHCQEKESEAHRKHTMLQECKERISALNLQI 144
+ ++ ++E + +E +R +E+E + + ++E + ++ Q+
Sbjct: 65 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 124
Query: 145 EEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKA 204
E++ + R+ E Q+ + GQ ++ ++ ++ + + Q+ ++E V+
Sbjct: 125 REQEGQVREQ----EGQVREQEGQVRE-----QEGQVREQEGQVREQEGQVREQEGQVRE 175
Query: 205 TLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAAT----VQLFQEEHRKAEELLAAAAQR 260
V+ Q + EG EG +E +Q +E+ + EE + ++
Sbjct: 176 QEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
Query: 261 HQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
+ +++ Q+Q+++ Q+ +E++ K Q+ Q + +E+E
Sbjct: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQE 275
Score = 35.0 bits (79), Expect = 0.088
Identities = 31/184 (16%), Positives = 80/184 (43%), Gaps = 33/184 (17%)
Query: 117 QEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFH 176
+E+E + + ++E + ++ Q+ E++ + R+ EQ E MG+ ++
Sbjct: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQ-EGQMGEQEEQMG-E 210
Query: 177 MPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEA 236
E++ K+ + +EQ+ K+E+ + E V+ Q
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ------------------------ 246
Query: 237 AATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQST 296
+E+ +K EE + ++ ++ +++ ++Q+++ + KE+ E+ + Q
Sbjct: 247 -------EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299
Query: 297 QEEE 300
++EE
Sbjct: 300 EQEE 303
Score = 32.0 bits (71), Expect = 0.75
Identities = 28/145 (19%), Positives = 68/145 (46%), Gaps = 7/145 (4%)
Query: 19 RAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEAR 78
R ++ ++ Q E +M ++ +++G E ++ ++ E ++ K + +GE
Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE 358
Query: 79 TICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERIS 138
E +QK+ + + ++ E + K++E +R +++E + + + E KE++
Sbjct: 359 ---EQMQKQEEQVRKQE----EQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
Query: 139 ALNLQIEEEKNKQRQLRLAFEEQLE 163
Q+ E+K + R+ EQ E
Sbjct: 412 EQEEQMGEQKEQMRKQEEHMGEQKE 436
>gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein 3
isoform 1 [Homo sapiens]
Length = 632
Score = 58.5 bits (140), Expect = 7e-09
Identities = 66/312 (21%), Positives = 131/312 (41%), Gaps = 53/312 (16%)
Query: 28 TSSQKIEDLMEMVQKLQKV-GSLEPRVEVLINRINEVQQAKK----------KANKDLGE 76
TSS ++DL Q+ V S + L N I ++Q KK KAN +
Sbjct: 67 TSSATLKDLESPCQERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQK 126
Query: 77 ARTICEA----LQKELDSLHGEKVHLKEIL---SKKQETLRILRLHCQEKESEAH----- 124
A+ + E L + + L+ + H+K L +K + L + H +++ E
Sbjct: 127 AKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSN 186
Query: 125 ------------------RKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLM 166
R L++ + L +Q+ + K +Q++L +E E L
Sbjct: 187 VMATQKKKANQLSSRSKARTEWKLEQSMREEALLKVQLTQFKESFQQVQLERDEYSEHLK 246
Query: 167 GQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLD 226
G+ + W M ++++EIC L K+Q ++ + ++ +L +K+Q+ E P+
Sbjct: 247 GE-RARWQQRM-RKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPS 304
Query: 227 EGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHG 286
E +Q ++E + L A + +Q++ Q+Q+++ + +E L K
Sbjct: 305 E----------VELQHLRKELERVAGELQAQVKNNQRISLLNQRQEERIREQEERLRKQE 354
Query: 287 MQVPAQAQSTQE 298
++ Q +S Q+
Sbjct: 355 ERIQEQHKSLQQ 366
Score = 28.5 bits (62), Expect = 8.2
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Query: 38 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKA---NKDLGEARTICEALQKELDSLHGE 94
E Q +++V LE + L N++ E + A +L R E + EL +
Sbjct: 269 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKN 328
Query: 95 KVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 154
+ + +++E +R +++E +H LQ+ + S + +E N + +
Sbjct: 329 NQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQS-----VFKEPNNENKN 383
Query: 155 RLAFEEQLEDL 165
L E+Q+++L
Sbjct: 384 ALQLEQQVKEL 394
>gi|239745085 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 3 [Homo sapiens]
Length = 601
Score = 57.8 bits (138), Expect = 1e-08
Identities = 74/318 (23%), Positives = 133/318 (41%), Gaps = 45/318 (14%)
Query: 31 QKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDS 90
Q + L E + + E +EV I R+N +Q K K N DL + ++E
Sbjct: 113 QVVHQLEEEKKANNEKQKAERELEVQIQRLN-IQ--KGKLNTDLYHTKRSLRYFEEESKD 169
Query: 91 LHGEKVHLKEILSKKQETLRILRL--HCQEKESEAH------RKHTMLQECKERISALNL 142
L V L+ L +K E R L Q+K++E R L++ + L
Sbjct: 170 L---AVRLQHSLQRKGELERALSAVTATQKKKAERFSSRSKARTEWKLEQSMREQALLKA 226
Query: 143 QIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLV 202
Q+ + K ++++L +E E L G+ + W M ++++E+C+L K+ + +
Sbjct: 227 QLTQLKESLKEVQLERDEYAEHLKGE-RARWQQRM-RKMSQEVCSLKKEKKHDKYRVETL 284
Query: 203 KATLEDVKHQLCSLCGAEGPSTLDEG----LFLRSQEAAATVQLFQEEHRKAEELLAAAA 258
+ +L +K+Q+ E P+ E L + A +Q E +++ L
Sbjct: 285 ERSLSKLKNQMAEPLPPEPPAVPSEAELQHLRKELERVAGALQAQVEYNQRISLLNEGQK 344
Query: 259 QRHQQLQQKCQQQQQKRQRL------------------------KEELEKHGMQVPAQAQ 294
+R ++ Q++ +Q+++ Q+L KE EK G ++
Sbjct: 345 ERLREQQERLPEQEERLQQLAEPQNSFKELNNENKSVLQLEQQVKELQEKLGKRLAHLVA 404
Query: 295 STQEE-EAGPGDVAPRPG 311
S Q+E EA G AP PG
Sbjct: 405 SAQKEPEAARGPGAPGPG 422
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 57.4 bits (137), Expect = 2e-08
Identities = 74/314 (23%), Positives = 137/314 (43%), Gaps = 52/314 (16%)
Query: 31 QKIEDL-MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELD 89
Q++E+ M++ QKV SLE ++ + ++ ++ + + K K L + + ++ELD
Sbjct: 1500 QQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELD 1559
Query: 90 SLHGEKVHLKEI-LSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEE- 147
G L++ L + E R+ + H +E ES Q C++++ + +Q+EEE
Sbjct: 1560 EQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY 1619
Query: 148 KNKQRQLR--LAFEEQLEDLMGQHKDLWDFHMPERLAK---------------------- 183
++KQ+ LR E +L L Q + DF +RL K
Sbjct: 1620 EDKQKVLREKRELEGKLATLSDQ-VNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNS 1678
Query: 184 -----EICALDSSKEQ-------LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFL 231
EI L + E+ +K K ++ +ED+ Q+ + A+ + L+E L
Sbjct: 1679 APSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI--AKAKTALEEQLSR 1736
Query: 232 RSQEAAATVQLFQEEHRKAEELL----AAAAQRHQ------QLQQKCQQQQQKRQRLKEE 281
+E +E+ EL+ AA AQ + LQ + ++ +++Q L+E+
Sbjct: 1737 LQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEK 1796
Query: 282 LEKHGMQVPAQAQS 295
L+ QV QS
Sbjct: 1797 LQALQSQVEFLEQS 1810
Score = 51.6 bits (122), Expect = 9e-07
Identities = 57/231 (24%), Positives = 108/231 (46%), Gaps = 31/231 (13%)
Query: 21 EKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTI 80
EK Q+ + ED+ E+++K + + R + +IN++Q ++ANK+ E +
Sbjct: 1740 EKNEIQNRLEEDQEDMNELMKKHKAAVAQASRD---LAQINDLQAQLEEANKEKQELQEK 1796
Query: 81 CEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKE----- 135
+ALQ +++ L V K ++S+++ +R L + + ++ R ++ KE
Sbjct: 1797 LQALQSQVEFLEQSMVD-KSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKL 1855
Query: 136 ------RISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQ--HKDLWDFHMPERLAKEICA 187
RI+A N + E+ K QRQLR EE MG+ K+ L ++ +
Sbjct: 1856 TEERDQRIAAENREKEQNKRLQRQLRDTKEE-----MGELARKEAEASRKKHELEMDLES 1910
Query: 188 LDSSKEQLLKEEKL-------VKATLED--VKHQLCSLCGAEGPSTLDEGL 229
L+++ + L + KL ++A +ED + L +EG S +D L
Sbjct: 1911 LEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSEL 1961
Score = 38.1 bits (87), Expect = 0.010
Identities = 42/212 (19%), Positives = 85/212 (40%), Gaps = 17/212 (8%)
Query: 99 KEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL---- 154
+E + K E ++ LR ++ E E + + RIS L ++ +E+N
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 155 ------RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLED 208
RL E+++++L Q+ L + E+ ++ + +L++ ++ +D
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDAL-------KKQMEVMEMEVMEARLIRAAEINGEVDDD 1365
Query: 209 VKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKC 268
L +D QE +++ Q+ R+ E L ++ Q+
Sbjct: 1366 DAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRAL 1425
Query: 269 QQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 300
QQ ++K QRL EL+ + + Q E E
Sbjct: 1426 QQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457
Score = 36.2 bits (82), Expect = 0.040
Identities = 55/294 (18%), Positives = 127/294 (43%), Gaps = 33/294 (11%)
Query: 32 KIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSL 91
K E++ ++ KL+K + R E+ +N + ++ + +L + R E+ + LD+
Sbjct: 1259 KDEEIQQLRSKLEKAE--KERNELRLNS-DRLESRISELTSELTDERNTGESASQLLDAE 1315
Query: 92 HGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQ 151
E++ ++ + + Q L+ + E E + R + +N +++++ +
Sbjct: 1316 TAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLI------RAAEINGEVDDD-DAG 1368
Query: 152 RQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKH 211
+ RL +E + ++ D + + ++ +K QL + ++A E+ +
Sbjct: 1369 GEWRLKYERAVREV-----DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR 1423
Query: 212 QLCSL---CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQ-QK 267
L L C D L L Q+ +L +++ R EL +Q H++ Q +K
Sbjct: 1424 ALQQLKKKCQRLTAELQDTKLHLEGQQVR-NHELEKKQRRFDSEL----SQAHEEAQREK 1478
Query: 268 CQQQQQKRQR---------LKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGR 312
Q+++ +R++ LK++LE+ M + Q EA D++ + +
Sbjct: 1479 LQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1532
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,480,405
Number of Sequences: 37866
Number of extensions: 597127
Number of successful extensions: 10835
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 360
Number of HSP's successfully gapped in prelim test: 765
Number of HSP's that attempted gapping in prelim test: 4535
Number of HSP's gapped (non-prelim): 3857
length of query: 318
length of database: 18,247,518
effective HSP length: 102
effective length of query: 216
effective length of database: 14,385,186
effective search space: 3107200176
effective search space used: 3107200176
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.