Search of human proteins with 216548487

Search of human proteins with 216548487

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|216548487 peptidyl arginine deiminase, type IV [Homo
sapiens]
         (663 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|216548487 peptidyl arginine deiminase, type IV [Homo sapiens]     1365   0.0  
gi|122056685 peptidylarginine deiminase type I [Homo sapiens]         761   0.0  
gi|122939161 peptidyl arginine deiminase, type III [Homo sapiens]     721   0.0  
gi|122939159 peptidyl arginine deiminase, type II [Homo sapiens]      662   0.0  
gi|117414158 peptidylarginine deiminase type 6 [Homo sapiens]         594   e-170
gi|54859722 nucleoporin 160kDa [Homo sapiens]                          30   5.5  
gi|116295258 integrin alpha 2 precursor [Homo sapiens]                 30   7.1  
gi|44890059 involucrin [Homo sapiens]                                  30   9.3  
gi|31542507 HORMA domain containing 1 [Homo sapiens]                   30   9.3  
gi|41281453 serine/threonine kinase 2 [Homo sapiens]                   30   9.3  

>gi|216548487 peptidyl arginine deiminase, type IV [Homo sapiens]
          Length = 663

 Score = 1365 bits (3533), Expect = 0.0
 Identities = 663/663 (100%), Positives = 663/663 (100%)

Query: 1   MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 60
           MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK
Sbjct: 1   MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 60

Query: 61  KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD 120
           KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD
Sbjct: 61  KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD 120

Query: 121 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM 180
           ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM
Sbjct: 121 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM 180

Query: 181 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV 240
           SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV
Sbjct: 181 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV 240

Query: 241 PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP 300
           PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP
Sbjct: 241 PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP 300

Query: 301 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP 360
           NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP
Sbjct: 301 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP 360

Query: 361 HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG 420
           HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG
Sbjct: 361 HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG 420

Query: 421 KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP 480
           KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP
Sbjct: 421 KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP 480

Query: 481 APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS 540
           APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS
Sbjct: 481 APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS 540

Query: 541 FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK 600
           FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK
Sbjct: 541 FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK 600

Query: 601 PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN 660
           PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN
Sbjct: 601 PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN 660

Query: 661 MVP 663
           MVP
Sbjct: 661 MVP 663


>gi|122056685 peptidylarginine deiminase type I [Homo sapiens]
          Length = 663

 Score =  761 bits (1965), Expect = 0.0
 Identities = 381/669 (56%), Positives = 486/669 (72%), Gaps = 12/669 (1%)

Query: 1   MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 60
           MA   +++++ + PTHAVCV+G    +DI S  P+   SF ++ S GV V + +     K
Sbjct: 1   MAPKRVVQLSLKMPTHAVCVVGVEAHVDIHSDVPKGANSFRVSGSSGVEVFMVYNRTRVK 60

Query: 61  KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPV--KALLYLTGVEISLC 118
           +  G + WPLD   ++ +++  AS    D KV++SY+G +      +++LYLTGV+ISL 
Sbjct: 61  EPIGKARWPLDTDADMVVSVGTASKELKDFKVRVSYFGEQEDQALGRSVLYLTGVDISLE 120

Query: 119 ADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQ 178
            D  RTGKVK  R+  D++TW WGP G GAILLVNCDRDN  S+  D     ++   DLQ
Sbjct: 121 VDTGRTGKVK--RSQGDKKTWRWGPEGYGAILLVNCDRDNHRSAEPDLTHSWLMSLADLQ 178

Query: 179 DMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYL 238
           DMS M LS   P   F +H LVL+V  S+  +VRVF A  G   S    VLGP+  S+ +
Sbjct: 179 DMSPMLLSCNGPDKLFDSHKLVLNVPFSDSKRVRVFCARGGNSLSDYKQVLGPQCLSYEV 238

Query: 239 MVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIM 298
               G+  + FYVE L FPD DF GL++L++SL+D   L  PE  +F D+V FR+APWIM
Sbjct: 239 ERQPGEQEIKFYVEGLTFPDADFLGLVSLSVSLVDPGTL--PEVTLFTDTVGFRMAPWIM 296

Query: 299 TPNTQPPQEVYACSIFE----NEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEI 354
           TPNTQPP+E+Y C + +    NE FL+ ++ L +KA CKLTICP+ EN +D+W+QDEME 
Sbjct: 297 TPNTQPPEELYVCRVMDTHGSNEKFLEDMSYLTLKANCKLTICPQVENRNDRWIQDEMEF 356

Query: 355 GYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSP 414
           GYI+APHK+ PVVFDSPRNRGLK+FP KR++GPDFGYVTR     G S LDSFGNL+VSP
Sbjct: 357 GYIEAPHKSFPVVFDSPRNRGLKDFPYKRILGPDFGYVTREIPLPGPSSLDSFGNLDVSP 416

Query: 415 PVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDE 474
           PVTV G EYPLGRIL G S +P +  RQM +A+++FL AQQVQAPV+LYSDWLSVGHVDE
Sbjct: 417 PVTVGGTEYPLGRILIGSS-FPKSGGRQMARAVRNFLKAQQVQAPVELYSDWLSVGHVDE 475

Query: 475 FLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKT 534
           FL+FVP  D+KGFRLLLASP +C KLFQE++ EG+GEA  F+G+K + ++ I  +L+++ 
Sbjct: 476 FLTFVPTSDQKGFRLLLASPSACLKLFQEKKEEGYGEAAQFDGLKHQAKRSINEMLADRH 535

Query: 535 LREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGK 594
           L+  N   ++CIDWNR +LKRELGLAESDI+DIPQLF LK F  AEAFFP+MVNM+VLGK
Sbjct: 536 LQRDNLHAQKCIDWNRNVLKRELGLAESDIVDIPQLFFLKNF-YAEAFFPDMVNMVVLGK 594

Query: 595 HLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPF 654
           +LGIPKP+GP+INGRCCLEEKV SLLEPLGL C FI+D+ +YH   GE+HCGTNVRRKPF
Sbjct: 595 YLGIPKPYGPIINGRCCLEEKVQSLLEPLGLHCIFIDDYLSYHELQGEIHCGTNVRRKPF 654

Query: 655 SFKWWNMVP 663
            FKWWNMVP
Sbjct: 655 PFKWWNMVP 663


>gi|122939161 peptidyl arginine deiminase, type III [Homo sapiens]
          Length = 664

 Score =  721 bits (1861), Expect = 0.0
 Identities = 374/669 (55%), Positives = 461/669 (68%), Gaps = 11/669 (1%)

Query: 1   MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 60
           M+   ++RV+ E PT AVCV G  T +DI  S PE    F +  +PGV + I+      +
Sbjct: 1   MSLQRIVRVSLEHPTSAVCVAGVETLVDIYGSVPEGTEMFEVYGTPGVDIYISPNMERGR 60

Query: 61  KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTP-PVK-ALLYLTGVEISLC 118
           +   +  W  D  +E+ + M   S    D  VQISY+    P P+  A+LYLT V+ISL 
Sbjct: 61  ERADTRRWRFDATLEIIVVMNSPSNDLNDSHVQISYHSSHEPLPLAYAVLYLTCVDISLD 120

Query: 119 ADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQ 178
            D+   G+    R   D+R W WGP G G ILLVNCDRD+      D  D  V   +DL+
Sbjct: 121 CDLNCEGR--QDRNFVDKRQWVWGPSGYGGILLVNCDRDDPSCDVQDNCDQHVHCLQDLE 178

Query: 179 DMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGK-LSSKCSVVLGPKWPSHY 237
           DMS+M L T+ P   F +H LVLH +  +  + +VF     + +      VLG    S+ 
Sbjct: 179 DMSVMVLRTQGPAALFDDHKLVLHTSSYDAKRAQVFHICGPEDVCEAYRHVLGQDKVSYE 238

Query: 238 LMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWI 297
           +    G     F+VE L+FPD  F GLI+  ++LLD SN +   + +F D+VVFRVAPWI
Sbjct: 239 VPRLHGDEER-FFVEGLSFPDAGFTGLISFHVTLLDDSNEDFSASPIFTDTVVFRVAPWI 297

Query: 298 MTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYI 357
           MTP+T PP EVY C +  N  F+ +V  LA KA CKLTICP+ EN +D+W+QDEME+GY+
Sbjct: 298 MTPSTLPPLEVYVCRVRNNTCFVDAVAELARKAGCKLTICPQAENRNDRWIQDEMELGYV 357

Query: 358 QAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVT 417
           QAPHKTLPVVFDSPRN  L++FP KR++GPDFGYVTR P+   +SGLDSFGNLEVSPPV 
Sbjct: 358 QAPHKTLPVVFDSPRNGELQDFPYKRILGPDFGYVTREPRDRSVSGLDSFGNLEVSPPVV 417

Query: 418 VRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLS 477
             GKEYPLGRIL G +  P +  R++ Q ++DFL AQ+VQ PV+L+ DWL+VGHVDEFLS
Sbjct: 418 ANGKEYPLGRILIGGN-LPGSSGRRVTQVVRDFLHAQKVQPPVELFVDWLAVGHVDEFLS 476

Query: 478 FVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQK---IKNILSNKT 534
           FVPAPD KGFR+LLASP +C+KLFQE+Q  GHG ALLF+G+   +Q K   I  +LSNK 
Sbjct: 477 FVPAPDGKGFRMLLASPGACFKLFQEKQKCGHGRALLFQGVVDDEQVKTISINQVLSNKD 536

Query: 535 LREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGK 594
           L  +N FV+ CIDWNRE+LKRELGLAE DIIDIPQLFK  E  KA AFFP++VNMLVLGK
Sbjct: 537 LINYNKFVQSCIDWNREVLKRELGLAECDIIDIPQLFK-TERKKATAFFPDLVNMLVLGK 595

Query: 595 HLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPF 654
           HLGIPKPFGP+ING CCLEEKV SLLEPLGL CTFI+DF  YH+ HGEVHCGTNV RKPF
Sbjct: 596 HLGIPKPFGPIINGCCCLEEKVRSLLEPLGLHCTFIDDFTPYHMLHGEVHCGTNVCRKPF 655

Query: 655 SFKWWNMVP 663
           SFKWWNMVP
Sbjct: 656 SFKWWNMVP 664


>gi|122939159 peptidyl arginine deiminase, type II [Homo sapiens]
          Length = 665

 Score =  662 bits (1709), Expect = 0.0
 Identities = 337/668 (50%), Positives = 440/668 (65%), Gaps = 8/668 (1%)

Query: 1   MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 60
           M +   +R+       AV VLGT    D+ S+AP    +FS+  S  V V++     A++
Sbjct: 1   MLRERTVRLQYGSRVEAVYVLGTYLWTDVYSAAPAGAQTFSLKHSEHVWVEVVRDGEAEE 60

Query: 61  KST-GSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPK--TPPVKALLYLTGVEISL 117
            +T G   W L P   + +TM  AS      KV ++YY  +   P  +A L+LT +EISL
Sbjct: 61  VATNGKQRWLLSPSTTLRVTMSQASTEASSDKVTVNYYDEEGSIPIDQAGLFLTAIEISL 120

Query: 118 CADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDL 177
             D  R G V+     K   +WTWGP GQGAILLVNCDR+       DC D++V   EDL
Sbjct: 121 DVDADRDGVVEKNNPKK--ASWTWGPEGQGAILLVNCDRETPWLPKEDCRDEKVYSKEDL 178

Query: 178 QDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHY 237
           +DMS M L TK P      + +VL+++ S+ DKV VF         +   +LG +   H 
Sbjct: 179 KDMSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENPFFGQRYIHILGRRKLYHV 238

Query: 238 LMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWI 297
           +   GG   + F+VE L FPD  F GL+++ +SLL+    ++P   +F D+V+FR+APWI
Sbjct: 239 VKYTGGSAELLFFVEGLCFPDEGFSGLVSIHVSLLEYMAQDIPLTPIFTDTVIFRIAPWI 298

Query: 298 MTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYI 357
           MTPN  PP  V+ C + +N  FLK V  L  K  C+L +C +  N  D+W+QDE+E GYI
Sbjct: 299 MTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYLNRGDRWIQDEIEFGYI 358

Query: 358 QAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVT 417
           +APHK  PVV DSPR+  LK+FP+K ++GPDFGYVTR P    ++ LDSFGNLEVSPPVT
Sbjct: 359 EAPHKGFPVVLDSPRDGNLKDFPVKELLGPDFGYVTREPLFESVTSLDSFGNLEVSPPVT 418

Query: 418 VRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLS 477
           V GK YPLGRIL G S +P +  R+M + ++DFL AQQVQAPV+LYSDWL+VGHVDEF+S
Sbjct: 419 VNGKTYPLGRILIGSS-FPLSGGRRMTKVVRDFLKAQQVQAPVELYSDWLTVGHVDEFMS 477

Query: 478 FVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGI--KKKKQQKIKNILSNKTL 535
           FVP P  K F LL+AS  +CYKLF+E+Q +GHGEA++F+G+     K+  I  ILSN++L
Sbjct: 478 FVPIPGTKKFLLLMASTSACYKLFREKQKDGHGEAIMFKGLGGMSSKRITINKILSNESL 537

Query: 536 REHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKH 595
            + N + +RC+DWNR++LK+ELGL E DIID+P LFK+ E  +A AFFPNMVNM+VL K 
Sbjct: 538 VQENLYFQRCLDWNRDILKKELGLTEQDIIDLPALFKMDEDHRARAFFPNMVNMIVLDKD 597

Query: 596 LGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFS 655
           LGIPKPFGP +   CCLE  V  LLEPLGL+CTFI+D   YH   GEVHCGTNVRRKPF+
Sbjct: 598 LGIPKPFGPQVEEECCLEMHVRGLLEPLGLECTFIDDISAYHKFLGEVHCGTNVRRKPFT 657

Query: 656 FKWWNMVP 663
           FKWW+MVP
Sbjct: 658 FKWWHMVP 665


>gi|117414158 peptidylarginine deiminase type 6 [Homo sapiens]
          Length = 694

 Score =  594 bits (1531), Expect = e-170
 Identities = 308/688 (44%), Positives = 443/688 (64%), Gaps = 27/688 (3%)

Query: 1   MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 60
           M+  ++I ++ + P HAVCVLGT   LD+   AP+ C  F+I+ S  V++D+A+   ++K
Sbjct: 9   MSFQSIIHLSLDSPVHAVCVLGTEICLDLSGCAPQKCQCFTIHGSGRVLIDVANTVISEK 68

Query: 61  KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPK--TPPVKALLYLTGVEISLC 118
           +   +  WPL      T+ M   S S    KV ++YYGP    P   A+LYLTG+E+SL 
Sbjct: 69  EDA-TIWWPLSDPTYATVKMTSPSPSVDADKVSVTYYGPNEDAPVGTAVLYLTGIEVSLE 127

Query: 119 ADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQ 178
            DI R G+V+ +   + ++ W WGP G GAILLVNC+  ++     D +  +V+ SE++ 
Sbjct: 128 VDIYRNGQVEMSSDKQAKKKWIWGPSGWGAILLVNCNPADVGQQLEDKKTKKVIFSEEIT 187

Query: 179 DMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYL 238
           ++S MTL+ + P      + LVLH ++ E  K RV+   +   SS   +VLGP   ++ L
Sbjct: 188 NLSQMTLNVQGPSCILKKYRLVLHTSKEESKKARVYWPQKDN-SSTFELVLGPDQHAYTL 246

Query: 239 MVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTS-NLELPEAVVFQDSVVFRVAPWI 297
            + G      FYVEA+AFP  +F GLI+ ++SL++ S +  +PE V+++D+VVFRVAP +
Sbjct: 247 ALLGNHLKETFYVEAIAFPSAEFSGLISYSVSLVEESQDPSIPETVLYKDTVVFRVAPCV 306

Query: 298 MTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYI 357
             P TQ P EVY C   + + F+ +VT L+ K+  ++    E+ N   +W+QDEM   Y 
Sbjct: 307 FIPCTQVPLEVYLCRELQLQGFVDTVTKLSEKSNSQVASVYEDPNRLGRWLQDEMAFCYT 366

Query: 358 QAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVT 417
           QAPHKT  ++ D+P+   L EFP+K  + P  GY+ +  +   ++ +DS GNL VSPPV 
Sbjct: 367 QAPHKTTSLILDTPQAADLDEFPMKYSLSPGIGYMIQDTEDHKVASMDSIGNLMVSPPVK 426

Query: 418 VRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLS 477
           V+GKEYPLGR+L G S YPS + R M + L+DFL AQQVQAPV+LYSDWL  GHVDEF+ 
Sbjct: 427 VQGKEYPLGRVLIGSSFYPSAEGRAMSKTLRDFLYAQQVQAPVELYSDWLMTGHVDEFMC 486

Query: 478 FVPAPD----RKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKK-------KKQQKI 526
           F+P  D    +KGF LLLASP +CYKLF+E+Q EG+G+ALLF+ ++        ++ + I
Sbjct: 487 FIPTDDKNEGKKGFLLLLASPSACYKLFREKQKEGYGDALLFDELRADQLLSNGREAKTI 546

Query: 527 KNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEF---------- 576
             +L++++L++ N +VE+CI  NR++LK ELGL E DII+IPQLF L++           
Sbjct: 547 DQLLADESLKKQNEYVEKCIHLNRDILKTELGLVEQDIIEIPQLFCLEKLTNIPSDQQPK 606

Query: 577 -SKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFT 635
            S A  +FP+++ M+V+GK+LGIPKPFGP I G CCLEEK+C LLEPLG +CTFINDF  
Sbjct: 607 RSFARPYFPDLLRMIVMGKNLGIPKPFGPQIKGTCCLEEKICCLLEPLGFKCTFINDFDC 666

Query: 636 YHIRHGEVHCGTNVRRKPFSFKWWNMVP 663
           Y    G++    N+RR PF+FKWW MVP
Sbjct: 667 YLTEVGDICACANIRRVPFAFKWWKMVP 694


>gi|54859722 nucleoporin 160kDa [Homo sapiens]
          Length = 1436

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 13/91 (14%)

Query: 273 DTSNLELPEAVVFQDSVVFRVAPWIMTP---------NTQPPQEVYACSIFENEDFLKSV 323
           D  N  + + + F+ +V  +  P  M P         + Q P+E+Y  S+F    F    
Sbjct: 412 DAENQTVVKYINFEHNVAGQWNPVFMQPLPEEEIVIRDDQDPREMYLQSLFTPGQFTNEA 471

Query: 324 TTLAMKAKCKLTICPEEENMDDQWMQDEMEI 354
              A++  C+ T    E N+D  W + + E+
Sbjct: 472 LCKALQIFCRGT----ERNLDLSWSELKKEV 498


>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
          Length = 1181

 Score = 30.0 bits (66), Expect = 7.1
 Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 1/62 (1%)

Query: 71   DPGVEVTLTMKVASGSTGDQKVQISYYGPK-TPPVKALLYLTGVEISLCADITRTGKVKP 129
            D G +   ++KV +GS       +  + P+ T     L+YLTGV+     DI+    + P
Sbjct: 966  DVGPKFIFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINP 1025

Query: 130  TR 131
             +
Sbjct: 1026 LK 1027


>gi|44890059 involucrin [Homo sapiens]
          Length = 585

 Score = 29.6 bits (65), Expect = 9.3
 Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 10/74 (13%)

Query: 502 QEQQNEGHGEALLFEG----IKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRE- 556
           Q+Q  E H E    E     +K++K Q+ + +  NK L E    +++ +D  +EL+KR+ 
Sbjct: 88  QQQHWEQHEEYQKAENPEQQLKQEKTQRDQQL--NKQLEEEKKLLDQQLD--QELVKRDE 143

Query: 557 -LGLAESDIIDIPQ 569
            LG+ +  ++++P+
Sbjct: 144 QLGMKKEQLLELPE 157


>gi|31542507 HORMA domain containing 1 [Homo sapiens]
          Length = 394

 Score = 29.6 bits (65), Expect = 9.3
 Identities = 16/57 (28%), Positives = 32/57 (56%), Gaps = 4/57 (7%)

Query: 159 LESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQ 215
           LE  ++ CE+DE++ S++  D+S+    + +  +   N T  L ++ S+    +VFQ
Sbjct: 289 LEEPSLVCEEDEIMRSKESPDLSI----SHSQVEQLVNKTSELDMSESKTRSGKVFQ 341


>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
          Length = 1235

 Score = 29.6 bits (65), Expect = 9.3
 Identities = 17/57 (29%), Positives = 29/57 (50%)

Query: 499 KLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKR 555
           +L QE  N    EA   +G ++K+  K +N+L N+     N   +   +  +EL+KR
Sbjct: 891 RLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKR 947


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,106,295
Number of Sequences: 37866
Number of extensions: 1351857
Number of successful extensions: 2883
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2852
Number of HSP's gapped (non-prelim): 11
length of query: 663
length of database: 18,247,518
effective HSP length: 109
effective length of query: 554
effective length of database: 14,120,124
effective search space: 7822548696
effective search space used: 7822548696
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.