Guide to the Human Genome
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Search of human proteins with 21618357

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
         (282 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]          591   e-169
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]     526   e-150
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]       526   e-150
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]             295   2e-80
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]        268   4e-72
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]                     268   5e-72
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot...   266   1e-71
gi|11496281 kallikrein 13 precursor [Homo sapiens]                    265   3e-71
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ...   252   3e-67
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ...   252   3e-67
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa...   252   3e-67
gi|91823048 kallikrein 14 preproprotein [Homo sapiens]                247   7e-66
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]                    240   1e-63
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote...   231   5e-61
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei...   231   5e-61
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]           231   5e-61
gi|4504875 kallikrein 1 preproprotein [Homo sapiens]                  222   3e-58
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H...   221   4e-58
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho...   221   4e-58
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]                     219   2e-57
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho...   218   5e-57
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s...   212   3e-55
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]           211   8e-55
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]       209   2e-54
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]        209   2e-54
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]           204   9e-53
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo...   197   1e-50
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ...   197   1e-50
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ...   197   1e-50
gi|71834855 prostate specific antigen isoform 4 preproprotein [H...   183   2e-46

>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
          Length = 282

 Score =  591 bits (1523), Expect = e-169
 Identities = 282/282 (100%), Positives = 282/282 (100%)

Query: 1   MQRLRWLRDWKSSGRGLTAAKEPGARSSPLQAMRILQLILLALATGLVGGETRIIKGFEC 60
           MQRLRWLRDWKSSGRGLTAAKEPGARSSPLQAMRILQLILLALATGLVGGETRIIKGFEC
Sbjct: 1   MQRLRWLRDWKSSGRGLTAAKEPGARSSPLQAMRILQLILLALATGLVGGETRIIKGFEC 60

Query: 61  KPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRT 120
           KPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRT
Sbjct: 61  KPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRT 120

Query: 121 ATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWG 180
           ATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWG
Sbjct: 121 ATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWG 180

Query: 181 STSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLV 240
           STSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLV
Sbjct: 181 STSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLV 240

Query: 241 CNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 282
           CNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN
Sbjct: 241 CNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 282


>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
          Length = 250

 Score =  526 bits (1355), Expect = e-150
 Identities = 250/250 (100%), Positives = 250/250 (100%)

Query: 33  MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92
           MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA
Sbjct: 1   MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60

Query: 93  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 152
           AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV
Sbjct: 61  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 120

Query: 153 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212
           SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG
Sbjct: 121 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180

Query: 213 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 272
           NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV
Sbjct: 181 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 240

Query: 273 DWIQETMKNN 282
           DWIQETMKNN
Sbjct: 241 DWIQETMKNN 250


>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
          Length = 250

 Score =  526 bits (1355), Expect = e-150
 Identities = 250/250 (100%), Positives = 250/250 (100%)

Query: 33  MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92
           MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA
Sbjct: 1   MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60

Query: 93  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 152
           AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV
Sbjct: 61  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 120

Query: 153 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212
           SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG
Sbjct: 121 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180

Query: 213 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 272
           NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV
Sbjct: 181 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 240

Query: 273 DWIQETMKNN 282
           DWIQETMKNN
Sbjct: 241 DWIQETMKNN 250


>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
          Length = 250

 Score =  295 bits (756), Expect = 2e-80
 Identities = 138/242 (57%), Positives = 175/242 (72%)

Query: 40  LLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPR 99
           LL+L  G    +TR I   EC+P+SQPWQA LF  TRL CGATLI+ RWLLTAAHC KP 
Sbjct: 9   LLSLLAGHGWADTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPY 68

Query: 100 YIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVR 159
             V LG+H+L K EG EQ    T+ FPHPGFN  L   DH +DIML+++     ++ AV+
Sbjct: 69  LWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQ 128

Query: 160 PLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMV 219
           PL LS  CV+ G  CLISGWG+ SSP+   P TL+CANI+I+E++ C  AYPG+I+D+M+
Sbjct: 129 PLNLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSML 188

Query: 220 CASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETM 279
           CA + EGG+ SCQGDSGGPLVCN +L G++S G +PC+  R+P VYT VC Y+DWIQE M
Sbjct: 189 CAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQEIM 248

Query: 280 KN 281
           +N
Sbjct: 249 EN 250


>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
          Length = 260

 Score =  268 bits (685), Expect = 4e-72
 Identities = 125/254 (49%), Positives = 170/254 (66%), Gaps = 4/254 (1%)

Query: 26  RSSPLQAMRILQLILL--ALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATL 83
           R  P  A   + L+LL  A A      E +++ G EC+PHSQPWQAALF+  +LLCG  L
Sbjct: 3   RPRPRAAKTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVL 62

Query: 84  IAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDI 143
           +   W+LTAAHC KP+Y V LG H+LQ ++G EQ     +S PHP +N+S   +DH +D+
Sbjct: 63  VGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSS-DVEDHNHDL 121

Query: 144 MLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 203
           ML+++    S+   V+P++L+  C   G  C +SGWG+ +SP+   P TL CA + I   
Sbjct: 122 MLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQ 181

Query: 204 QKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPG 263
           +KCE+AYPG ITD MVCA   +G  D+CQGDSGGPLVC+ +LQGI SWG DPC  + KPG
Sbjct: 182 KKCEDAYPGQITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPG 240

Query: 264 VYTKVCKYVDWIQE 277
           VYT +C+Y+DWI++
Sbjct: 241 VYTNICRYLDWIKK 254


>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
          Length = 305

 Score =  268 bits (684), Expect = 5e-72
 Identities = 117/227 (51%), Positives = 160/227 (70%), Gaps = 2/227 (0%)

Query: 51  ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 110
           E +++ G EC+PHSQPWQAALF+  +LLCG  L+   W+LTAAHC KP+Y V LG H+LQ
Sbjct: 75  EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134

Query: 111 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 170
            ++G EQ     +S PHP +N+S   +DH +D+ML+++    S+   V+P++L+  C   
Sbjct: 135 NKDGPEQEIPVVQSIPHPCYNSS-DVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 193

Query: 171 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 230
           G  C +SGWG+ +SP+   P TL CA + I   +KCE+AYPG ITD MVCA   +G  D+
Sbjct: 194 GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DT 252

Query: 231 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQE 277
           CQGDSGGPLVC+ +LQGI SWG DPC  + KPGVYT +C+Y+DWI++
Sbjct: 253 CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299


>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
           [Homo sapiens]
          Length = 256

 Score =  266 bits (681), Expect = 1e-71
 Identities = 129/258 (50%), Positives = 169/258 (65%), Gaps = 15/258 (5%)

Query: 35  ILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 94
           +L L  L  +T    G+ ++++G EC PHSQPWQ AL+E+ R  CGA+LI+P W+L+AAH
Sbjct: 4   LLTLSFLLASTAAQDGD-KLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62

Query: 95  CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 154
           C      V LG+HNL+K +G EQ RT +   PHP +      + HRNDIML+++  P  +
Sbjct: 63  CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYE----ARSHRNDIMLLRLVQPARL 118

Query: 155 TWAVRPLTLSSRCVTAGTSCLISGWGSTS--------SP--QLRLPHTLRCANITIIEHQ 204
              VRP  L +RC   G +C++SGWG  S        SP  Q+ LP TL CANI+II   
Sbjct: 119 NPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDT 178

Query: 205 KCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGV 264
            C+ +YPG +T+TMVCA  +  G +SC+GDSGGPLVC   LQGI+SWG  PC  T KPGV
Sbjct: 179 SCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGV 238

Query: 265 YTKVCKYVDWIQETMKNN 282
           YTKVC Y++WI+ETMK N
Sbjct: 239 YTKVCHYLEWIRETMKRN 256


>gi|11496281 kallikrein 13 precursor [Homo sapiens]
          Length = 277

 Score =  265 bits (678), Expect = 3e-71
 Identities = 124/257 (48%), Positives = 174/257 (67%), Gaps = 11/257 (4%)

Query: 35  ILQLILLALATGLVGGETRIIK----------GFECKPHSQPWQAALFEKTRLLCGATLI 84
           ++  + LAL+ G+    ++++           G+ C PHSQPWQAAL  + RLLCG  L+
Sbjct: 7   VIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCGGVLV 66

Query: 85  APRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIM 144
            P+W+LTAAHCLK    V+LG+H L + E  EQ R    S PHP +  S  + +H +DIM
Sbjct: 67  HPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIM 126

Query: 145 LVKMASPVSITWAVRPLTLS-SRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 203
           L+++ SPV +T  ++ L LS +  +T GT+C +SGWG+T+SPQ+  P TL+CANI +   
Sbjct: 127 LLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSD 186

Query: 204 QKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPG 263
           ++C   YPG ITD M+CA  +EGGKDSC+GDSGGPLVCN++L GI+SWG  PC    +PG
Sbjct: 187 EECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPG 246

Query: 264 VYTKVCKYVDWIQETMK 280
           VYT+V +YV WI+ET++
Sbjct: 247 VYTRVSRYVLWIRETIR 263


>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  252 bits (643), Expect = 3e-67
 Identities = 118/233 (50%), Positives = 160/233 (68%), Gaps = 7/233 (3%)

Query: 52  TRIIKGFECKPHSQPWQAALFEK-TRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 110
           +RII G +C  H+QPWQAAL  +  +L CGA L+ P+WLLTAAHC K  + V LG ++L 
Sbjct: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124

Query: 111 KE-EGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVT 169
              E  +Q     +S PHPG+++      H ND+ML+K+   +  T  VRP+ +SS C +
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHP----GHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180

Query: 170 AGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKD 229
           AGT CL+SGWG+T SPQ+  P  L+C NI+++  ++CE+AYP  I DTM CA   + G+D
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKAGRD 239

Query: 230 SCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 282
           SCQGDSGGP+VCN SLQG++SWG  PCA   +PGVYT +CK+  WIQET++ N
Sbjct: 240 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292


>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  252 bits (643), Expect = 3e-67
 Identities = 118/233 (50%), Positives = 160/233 (68%), Gaps = 7/233 (3%)

Query: 52  TRIIKGFECKPHSQPWQAALFEK-TRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 110
           +RII G +C  H+QPWQAAL  +  +L CGA L+ P+WLLTAAHC K  + V LG ++L 
Sbjct: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124

Query: 111 KE-EGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVT 169
              E  +Q     +S PHPG+++      H ND+ML+K+   +  T  VRP+ +SS C +
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHP----GHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180

Query: 170 AGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKD 229
           AGT CL+SGWG+T SPQ+  P  L+C NI+++  ++CE+AYP  I DTM CA   + G+D
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKAGRD 239

Query: 230 SCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 282
           SCQGDSGGP+VCN SLQG++SWG  PCA   +PGVYT +CK+  WIQET++ N
Sbjct: 240 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292


>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  252 bits (643), Expect = 3e-67
 Identities = 118/233 (50%), Positives = 160/233 (68%), Gaps = 7/233 (3%)

Query: 52  TRIIKGFECKPHSQPWQAALFEK-TRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 110
           +RII G +C  H+QPWQAAL  +  +L CGA L+ P+WLLTAAHC K  + V LG ++L 
Sbjct: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124

Query: 111 KE-EGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVT 169
              E  +Q     +S PHPG+++      H ND+ML+K+   +  T  VRP+ +SS C +
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHP----GHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180

Query: 170 AGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKD 229
           AGT CL+SGWG+T SPQ+  P  L+C NI+++  ++CE+AYP  I DTM CA   + G+D
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKAGRD 239

Query: 230 SCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 282
           SCQGDSGGP+VCN SLQG++SWG  PCA   +PGVYT +CK+  WIQET++ N
Sbjct: 240 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292


>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
          Length = 267

 Score =  247 bits (631), Expect = 7e-66
 Identities = 121/258 (46%), Positives = 164/258 (63%), Gaps = 7/258 (2%)

Query: 27  SSPLQAMRILQLILLALA-TGLVGGETRIIKGFECKPHSQPWQAALFE--KTRLLCGATL 83
           S+P   + +  L +LA+A T     E +II G  C   SQPWQAAL    + R LCG  L
Sbjct: 13  SAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGAL 72

Query: 84  IAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDI 143
           ++ +W++TAAHC +P   V LG+HNL++ E  +Q         HP +N+    + H ND+
Sbjct: 73  LSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNS----RTHDNDL 128

Query: 144 MLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 203
           ML+++  P  I  AVRP+ ++  C + GTSC +SGWG+ SSP  R P +L+C NI I   
Sbjct: 129 MLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPD 188

Query: 204 QKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPG 263
           + C+ AYP  IT  MVCA V +GGKDSCQGDSGGPLVC   LQG++SWG + CA+   PG
Sbjct: 189 EVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPG 248

Query: 264 VYTKVCKYVDWIQETMKN 281
           VYT +CKY  WI+ETM++
Sbjct: 249 VYTNLCKYRSWIEETMRD 266


>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
          Length = 248

 Score =  240 bits (612), Expect = 1e-63
 Identities = 120/249 (48%), Positives = 155/249 (62%), Gaps = 5/249 (2%)

Query: 36  LQLILLALATGLVGGET-RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 94
           L + LL    GL    T +I  G EC  +SQPWQ  LFE T L CG  LI  RW+LTAAH
Sbjct: 3   LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62

Query: 95  CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 154
           C   RY V LG+H+L + +  EQ R +  S  HPG+  +  +  H +D+ L+++  PV +
Sbjct: 63  CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGA--STSHEHDLRLLRLRLPVRV 120

Query: 155 TWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNI 214
           T +V+PL L + C TAGT C +SGWG T+ P+   P  L+C N++I+ H  C   YPG I
Sbjct: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180

Query: 215 TDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQ-DPCAITRKPGVYTKVCKYVD 273
           T  MVCA     G+D+CQGDSGGPLVC   LQG++SWG   PC     PGVYT +CKYVD
Sbjct: 181 TSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVD 239

Query: 274 WIQETMKNN 282
           WI+  M+NN
Sbjct: 240 WIRMIMRNN 248


>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
           [Homo sapiens]
          Length = 244

 Score =  231 bits (589), Expect = 5e-61
 Identities = 107/248 (43%), Positives = 154/248 (62%), Gaps = 6/248 (2%)

Query: 33  MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92
           M+ L ++L  +A      + +++ G  C   S P+QAAL+    LLCG  LI P W+LTA
Sbjct: 1   MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60

Query: 93  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 152
           AHC KP   V LG+HNL++ E  ++  +   +  HP ++ +     H  DIML+++A P 
Sbjct: 61  AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAA----SHDQDIMLLRLARPA 116

Query: 153 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212
            ++  ++PL L   C    TSC I GWG T+      P T++CA I ++  ++CE+AYPG
Sbjct: 117 KLSELIQPLPLERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPG 174

Query: 213 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 272
            IT  M+CA  ++ GKDSCQGDSGGPLVC   L+G++SWG  PC    KPGVYT VC+Y 
Sbjct: 175 QITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYT 234

Query: 273 DWIQETMK 280
           +WIQ+T++
Sbjct: 235 NWIQKTIQ 242


>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
           [Homo sapiens]
          Length = 244

 Score =  231 bits (589), Expect = 5e-61
 Identities = 107/248 (43%), Positives = 154/248 (62%), Gaps = 6/248 (2%)

Query: 33  MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92
           M+ L ++L  +A      + +++ G  C   S P+QAAL+    LLCG  LI P W+LTA
Sbjct: 1   MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60

Query: 93  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 152
           AHC KP   V LG+HNL++ E  ++  +   +  HP ++ +     H  DIML+++A P 
Sbjct: 61  AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAA----SHDQDIMLLRLARPA 116

Query: 153 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212
            ++  ++PL L   C    TSC I GWG T+      P T++CA I ++  ++CE+AYPG
Sbjct: 117 KLSELIQPLPLERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPG 174

Query: 213 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 272
            IT  M+CA  ++ GKDSCQGDSGGPLVC   L+G++SWG  PC    KPGVYT VC+Y 
Sbjct: 175 QITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYT 234

Query: 273 DWIQETMK 280
           +WIQ+T++
Sbjct: 235 NWIQKTIQ 242


>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
          Length = 261

 Score =  231 bits (589), Expect = 5e-61
 Identities = 111/256 (43%), Positives = 159/256 (62%), Gaps = 11/256 (4%)

Query: 38  LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93
           ++ +AL+ G  G     ++RI+ G+EC+ HSQPWQ A++      CG  L+ P+W+LTAA
Sbjct: 5   VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAA 64

Query: 94  HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 146
           HCLK    V LG+HNL + E   Q    + SFPHP +N SL       P++D  +D+ML+
Sbjct: 65  HCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124

Query: 147 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 206
           +++ P  IT  V+ L L ++    GT+C  SGWGS    +   P +L+C ++ ++ +  C
Sbjct: 125 RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184

Query: 207 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 266
             AY   +T+ M+CA +  GGKD+C GDSGGPLVCN  LQGI SWG +PCA+  KP VYT
Sbjct: 185 ARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYT 244

Query: 267 KVCKYVDWIQETMKNN 282
           KV  Y  WI++T+  N
Sbjct: 245 KVVHYRKWIKDTIAAN 260


>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
          Length = 262

 Score =  222 bits (566), Expect = 3e-58
 Identities = 108/257 (42%), Positives = 158/257 (61%), Gaps = 12/257 (4%)

Query: 38  LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93
           ++ LAL+ G  G     ++RI+ G+EC+ HSQPWQAAL+  +   CG  L+  +W+LTAA
Sbjct: 5   VLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAA 64

Query: 94  HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 146
           HC+   Y + LG+HNL  +E   Q    +ESFPHPGFN SL        ++D+ +D+ML+
Sbjct: 65  HCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLL 124

Query: 147 KMASPV-SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQK 205
           ++  P  +IT AV+ + L +     G++CL SGWGS        P  L+C ++ I+ + +
Sbjct: 125 RLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDE 184

Query: 206 CENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVY 265
           C+ A+   +TD M+C    EGGKD+C GDSGGPL+C+  LQG+ SWG  PC    KP V 
Sbjct: 185 CKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVA 244

Query: 266 TKVCKYVDWIQETMKNN 282
            +V  YV WI++T+  N
Sbjct: 245 VRVLSYVKWIEDTIAEN 261


>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
           sapiens]
          Length = 253

 Score =  221 bits (564), Expect = 4e-58
 Identities = 108/250 (43%), Positives = 149/250 (59%), Gaps = 9/250 (3%)

Query: 36  LQLILLALATGLVGGET---RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92
           LQ++LL+LA    G E    +II G  C   S PWQ AL    +L CG  L+  RW+LTA
Sbjct: 9   LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68

Query: 93  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 152
           AHC    Y VHLG   L       Q   A++SF HPG++     + H ND+MLVK+ S  
Sbjct: 69  AHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST----QTHVNDLMLVKLNSQA 122

Query: 153 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212
            ++  V+ + L SRC   GT+C +SGWG+T+SP +  P  L C ++ +I  Q C   Y  
Sbjct: 123 RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182

Query: 213 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 272
            + ++M+CA + +  K++C GDSGGPLVC  +LQG++SWG  PC     PGVYT+VCK+ 
Sbjct: 183 LLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242

Query: 273 DWIQETMKNN 282
            WI +TMK +
Sbjct: 243 KWINDTMKKH 252


>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
           sapiens]
          Length = 253

 Score =  221 bits (564), Expect = 4e-58
 Identities = 108/250 (43%), Positives = 149/250 (59%), Gaps = 9/250 (3%)

Query: 36  LQLILLALATGLVGGET---RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92
           LQ++LL+LA    G E    +II G  C   S PWQ AL    +L CG  L+  RW+LTA
Sbjct: 9   LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68

Query: 93  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 152
           AHC    Y VHLG   L       Q   A++SF HPG++     + H ND+MLVK+ S  
Sbjct: 69  AHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST----QTHVNDLMLVKLNSQA 122

Query: 153 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212
            ++  V+ + L SRC   GT+C +SGWG+T+SP +  P  L C ++ +I  Q C   Y  
Sbjct: 123 RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182

Query: 213 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 272
            + ++M+CA + +  K++C GDSGGPLVC  +LQG++SWG  PC     PGVYT+VCK+ 
Sbjct: 183 LLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242

Query: 273 DWIQETMKNN 282
            WI +TMK +
Sbjct: 243 KWINDTMKKH 252


>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
          Length = 254

 Score =  219 bits (558), Expect = 2e-57
 Identities = 111/236 (47%), Positives = 144/236 (61%), Gaps = 5/236 (2%)

Query: 36  LQLILLALATGLVGGET-RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 94
           L + LL    GL    T +I  G EC  +SQPWQ  LFE T L CG  LI  RW+LTAAH
Sbjct: 3   LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62

Query: 95  CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 154
           C   RY V LG+H+L + +  EQ R +  S  HPG+  +  +  H +D+ L+++  PV +
Sbjct: 63  CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGA--STSHEHDLRLLRLRLPVRV 120

Query: 155 TWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNI 214
           T +V+PL L + C TAGT C +SGWG T+ P+   P  L+C N++I+ H  C   YPG I
Sbjct: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180

Query: 215 TDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQ-DPCAITRKPGVYTKVC 269
           T  MVCA     G+D+CQGDSGGPLVC   LQG++SWG   PC     PGVYT +C
Sbjct: 181 TSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYIC 235


>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
           sapiens]
          Length = 261

 Score =  218 bits (555), Expect = 5e-57
 Identities = 101/256 (39%), Positives = 154/256 (60%), Gaps = 11/256 (4%)

Query: 38  LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93
           ++ L L+   +G      +RI+ G+EC+ HSQPWQ  +  + R +CG  L+ P+W+LTAA
Sbjct: 5   VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64

Query: 94  HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 146
           HC++ + ++ LG+H+L   E   Q    + SFPHP ++ SL       P  D  +D+ML+
Sbjct: 65  HCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLL 124

Query: 147 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 206
           +++ P  +T AV+ + L ++    GT+C  SGWGS    +   P  L+C ++ +I +  C
Sbjct: 125 RLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC 184

Query: 207 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 266
              +P  +T  M+CA    GGK +C GDSGGPLVCN  LQGI SWG +PCA+  +P +YT
Sbjct: 185 AQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYT 244

Query: 267 KVCKYVDWIQETMKNN 282
           KV  Y  WI++T+  N
Sbjct: 245 KVVHYRKWIKDTIVAN 260


>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
           sapiens]
          Length = 254

 Score =  212 bits (539), Expect = 3e-55
 Identities = 103/247 (41%), Positives = 154/247 (62%), Gaps = 8/247 (3%)

Query: 36  LQLILLALATGLVGGE-TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 94
           L  ++L +A  LV G  ++II G +C PHSQPWQAAL  +  L C   L+ P+W+L+AAH
Sbjct: 12  LGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAH 71

Query: 95  CLKPRYIVHLGQHNLQKE-EGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 153
           C +  Y + LG H+L+ + E   Q   A+ S  HP +N  L      ND+ML+K+   VS
Sbjct: 72  CFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLL----ANDLMLIKLDESVS 127

Query: 154 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 213
            +  +R ++++S+C TAG SCL+SGWG  ++   R+P  L+C N++++  + C   Y   
Sbjct: 128 ESDTIRSISIASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPL 185

Query: 214 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 273
              +M CA      KDSC GDSGGPL+CN  LQG++S+G+ PC     PGVYT +CK+ +
Sbjct: 186 YHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245

Query: 274 WIQETMK 280
           WI++T++
Sbjct: 246 WIEKTVQ 252


>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
          Length = 247

 Score =  211 bits (536), Expect = 8e-55
 Identities = 109/253 (43%), Positives = 149/253 (58%), Gaps = 7/253 (2%)

Query: 30  LQAMRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWL 89
           +  + IL  +  ALA      + +I+ G+ C+ +S P+Q +L       CG +LI  +W+
Sbjct: 1   MNPLLILTFVAAALAAPF-DDDDKIVGGYNCEENSVPYQVSLNSGYHF-CGGSLINEQWV 58

Query: 90  LTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMA 149
           ++A HC K R  V LG+HN++  EG EQ   A +   HP ++    N    NDIML+K++
Sbjct: 59  VSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLN----NDIMLIKLS 114

Query: 150 SPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENA 209
           S   I   V  ++L +     GT CLISGWG+T+S     P  L+C +  ++   KCE +
Sbjct: 115 SRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEAS 174

Query: 210 YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVC 269
           YPG IT  M C    EGGKDSCQGDSGGP+VCN  LQG++SWG D CA   KPGVYTKV 
Sbjct: 175 YPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVY 233

Query: 270 KYVDWIQETMKNN 282
            YV WI+ T+  N
Sbjct: 234 NYVKWIKNTIAAN 246


>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
          Length = 304

 Score =  209 bits (533), Expect = 2e-54
 Identities = 103/232 (44%), Positives = 147/232 (63%), Gaps = 6/232 (2%)

Query: 51  ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 110
           + +I+ G+ C+ +S P+Q +L   +   CG +LI+ +W+++AAHC K R  V LG+HN++
Sbjct: 78  DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 136

Query: 111 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 170
             EG EQ   A +   HP +N    +    NDIML+K++SP  I   V  ++L +    A
Sbjct: 137 VLEGNEQFINAAKIIRHPKYNRDTLD----NDIMLIKLSSPAVINARVSTISLPTAPPAA 192

Query: 171 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 230
           GT CLISGWG+T S     P  L+C +  ++   +C+ +YPG IT++M C    EGGKDS
Sbjct: 193 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 252

Query: 231 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 282
           CQ DSGGP+VCN  LQG++SWG   CA   +PGVYTKV  YVDWI++T+  N
Sbjct: 253 CQRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 303


>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  209 bits (533), Expect = 2e-54
 Identities = 103/232 (44%), Positives = 147/232 (63%), Gaps = 6/232 (2%)

Query: 51  ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 110
           + +I+ G+ C+ +S P+Q +L   +   CG +LI+ +W+++AAHC K R  V LG+HN++
Sbjct: 21  DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 79

Query: 111 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 170
             EG EQ   A +   HP +N    +    NDIML+K++SP  I   V  ++L +    A
Sbjct: 80  VLEGNEQFINAAKIIRHPKYNRDTLD----NDIMLIKLSSPAVINARVSTISLPTAPPAA 135

Query: 171 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 230
           GT CLISGWG+T S     P  L+C +  ++   +C+ +YPG IT++M C    EGGKDS
Sbjct: 136 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 195

Query: 231 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 282
           CQ DSGGP+VCN  LQG++SWG   CA   +PGVYTKV  YVDWI++T+  N
Sbjct: 196 CQRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 246


>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  204 bits (518), Expect = 9e-53
 Identities = 107/250 (42%), Positives = 151/250 (60%), Gaps = 9/250 (3%)

Query: 36  LQLILLALATGLVG---GETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92
           L LIL  +A  +      + +I+ G+ C+ +S P+Q +L       CG +LI+ +W+++A
Sbjct: 3   LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSA 61

Query: 93  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 152
            HC K R  V LG+HN++  EG EQ   A +   HP +N+   +    NDI+L+K++SP 
Sbjct: 62  GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLD----NDILLIKLSSPA 117

Query: 153 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212
            I   V  ++L +    AGT  LISGWG+T S     P  L+C +  ++   +CE +YPG
Sbjct: 118 VINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPG 177

Query: 213 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 272
            IT+ M C    EGGKDSCQGDSGGP+V N  LQGI+SWG   CA   +PGVYTKV  YV
Sbjct: 178 KITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYG-CAQKNRPGVYTKVYNYV 236

Query: 273 DWIQETMKNN 282
           DWI++T+  N
Sbjct: 237 DWIKDTIAAN 246


>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
           sapiens]
          Length = 276

 Score =  197 bits (500), Expect = 1e-50
 Identities = 102/266 (38%), Positives = 153/266 (57%), Gaps = 9/266 (3%)

Query: 24  GARSSPLQAMRILQLILLALATGLVGGETRI---IKGFECKPHSQPWQAALFEKTRLLCG 80
           GAR+       ++  +  A A  L   +TR+     G  C   SQPWQ +LF      C 
Sbjct: 13  GARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCA 72

Query: 81  ATLIAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNS----LPN 136
             L+   W+LTAAHC        +G  +L   +G EQ R  T S  HP ++      LP 
Sbjct: 73  GVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPR 131

Query: 137 KDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCA 196
           +   +D+ML+K+A PV +   VR L L  RC   G  C ++GWG+T++ +++    L C+
Sbjct: 132 RTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCS 191

Query: 197 NITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPC 256
           +ITI+  ++CE  YPG +T+ M+CA + + G+D CQ DSGGPLVC+++LQGI+SWG  PC
Sbjct: 192 SITILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPC 250

Query: 257 AITRKPGVYTKVCKYVDWIQETMKNN 282
              + P VYT++CKY+ WI + +++N
Sbjct: 251 GSAQHPAVYTQICKYMSWINKVIRSN 276


>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
           sapiens]
          Length = 276

 Score =  197 bits (500), Expect = 1e-50
 Identities = 102/266 (38%), Positives = 153/266 (57%), Gaps = 9/266 (3%)

Query: 24  GARSSPLQAMRILQLILLALATGLVGGETRI---IKGFECKPHSQPWQAALFEKTRLLCG 80
           GAR+       ++  +  A A  L   +TR+     G  C   SQPWQ +LF      C 
Sbjct: 13  GARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCA 72

Query: 81  ATLIAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNS----LPN 136
             L+   W+LTAAHC        +G  +L   +G EQ R  T S  HP ++      LP 
Sbjct: 73  GVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPR 131

Query: 137 KDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCA 196
           +   +D+ML+K+A PV +   VR L L  RC   G  C ++GWG+T++ +++    L C+
Sbjct: 132 RTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCS 191

Query: 197 NITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPC 256
           +ITI+  ++CE  YPG +T+ M+CA + + G+D CQ DSGGPLVC+++LQGI+SWG  PC
Sbjct: 192 SITILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPC 250

Query: 257 AITRKPGVYTKVCKYVDWIQETMKNN 282
              + P VYT++CKY+ WI + +++N
Sbjct: 251 GSAQHPAVYTQICKYMSWINKVIRSN 276


>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
           sapiens]
          Length = 276

 Score =  197 bits (500), Expect = 1e-50
 Identities = 102/266 (38%), Positives = 153/266 (57%), Gaps = 9/266 (3%)

Query: 24  GARSSPLQAMRILQLILLALATGLVGGETRI---IKGFECKPHSQPWQAALFEKTRLLCG 80
           GAR+       ++  +  A A  L   +TR+     G  C   SQPWQ +LF      C 
Sbjct: 13  GARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCA 72

Query: 81  ATLIAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNS----LPN 136
             L+   W+LTAAHC        +G  +L   +G EQ R  T S  HP ++      LP 
Sbjct: 73  GVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPR 131

Query: 137 KDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCA 196
           +   +D+ML+K+A PV +   VR L L  RC   G  C ++GWG+T++ +++    L C+
Sbjct: 132 RTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCS 191

Query: 197 NITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPC 256
           +ITI+  ++CE  YPG +T+ M+CA + + G+D CQ DSGGPLVC+++LQGI+SWG  PC
Sbjct: 192 SITILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPC 250

Query: 257 AITRKPGVYTKVCKYVDWIQETMKNN 282
              + P VYT++CKY+ WI + +++N
Sbjct: 251 GSAQHPAVYTQICKYMSWINKVIRSN 276


>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
           sapiens]
          Length = 218

 Score =  183 bits (464), Expect = 2e-46
 Identities = 88/249 (35%), Positives = 133/249 (53%), Gaps = 40/249 (16%)

Query: 38  LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93
           ++ L L+   +G      +RI+ G+EC+ HSQPWQ  +  + R +CG  L+ P+W+LTAA
Sbjct: 5   VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64

Query: 94  HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 153
           HC++                                     P  D  +D+ML++++ P  
Sbjct: 65  HCIRK------------------------------------PGDDSSHDLMLLRLSEPAE 88

Query: 154 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 213
           +T AV+ + L ++    GT+C  SGWGS    +   P  L+C ++ +I +  C   +P  
Sbjct: 89  LTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 148

Query: 214 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 273
           +T  M+CA    GGK +C GDSGGPLVCN  LQGI SWG +PCA+  +P +YTKV  Y  
Sbjct: 149 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 208

Query: 274 WIQETMKNN 282
           WI++T+  N
Sbjct: 209 WIKDTIVAN 217


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,350,196
Number of Sequences: 37866
Number of extensions: 574299
Number of successful extensions: 1838
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1190
Number of HSP's gapped (non-prelim): 199
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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