Guide to the Human Genome
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Search of human proteins with 215598688

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|215598688 ubiquitin thiolesterase 13 [Homo sapiens]
         (863 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|215598688 ubiquitin thiolesterase 13 [Homo sapiens]               1771   0.0  
gi|148727247 ubiquitin specific peptidase 5 isoform 2 [Homo sapi...  1071   0.0  
gi|148727331 ubiquitin specific peptidase 5 isoform 1 [Homo sapi...  1068   0.0  
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]             82   2e-15
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]             82   2e-15
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]             82   2e-15
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]                   72   3e-12
gi|55770884 ubiquitin associated domain containing 1 [Homo sapiens]    65   3e-10
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]              55   3e-07
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]              55   3e-07
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]             53   1e-06
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]                 52   2e-06
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]                 52   2e-06
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]     52   2e-06
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]     52   2e-06
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]    52   3e-06
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]    52   3e-06
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]    52   3e-06
gi|21361517 UBX domain protein 1 [Homo sapiens]                        51   4e-06
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]            50   1e-05
gi|183396780 ubiquitin specific protease 20 [Homo sapiens]             48   3e-05
gi|183397136 ubiquitin specific protease 20 [Homo sapiens]             48   3e-05
gi|183397134 ubiquitin specific protease 20 [Homo sapiens]             48   3e-05
gi|41152235 ubiquitin specific protease 51 [Homo sapiens]              48   4e-05
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]    47   8e-05
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]    47   8e-05
gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens]             47   8e-05
gi|57529246 ubiquitin thioesterase 19 [Homo sapiens]                   47   1e-04
gi|82880645 ubiquitin specific protease 14 isoform b [Homo sapiens]    46   1e-04
gi|4827050 ubiquitin specific protease 14 isoform a [Homo sapiens]     45   2e-04

>gi|215598688 ubiquitin thiolesterase 13 [Homo sapiens]
          Length = 863

 Score = 1771 bits (4586), Expect = 0.0
 Identities = 863/863 (100%), Positives = 863/863 (100%)

Query: 1   MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEG 60
           MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEG
Sbjct: 1   MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEG 60

Query: 61  GLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDL 120
           GLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDL
Sbjct: 61  GLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDL 120

Query: 121 DTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPD 180
           DTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPD
Sbjct: 121 DTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPD 180

Query: 181 TWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSG 240
           TWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSG
Sbjct: 181 TWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSG 240

Query: 241 GNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG 300
           GNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG
Sbjct: 241 GNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG 300

Query: 301 TENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEF 360
           TENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEF
Sbjct: 301 TENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEF 360

Query: 361 QRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQ 420
           QRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQ
Sbjct: 361 QRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQ 420

Query: 421 QNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEER 480
           QNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEER
Sbjct: 421 QNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEER 480

Query: 481 IQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIP 540
           IQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIP
Sbjct: 481 IQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIP 540

Query: 541 FSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFD 600
           FSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFD
Sbjct: 541 FSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFD 600

Query: 601 VSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQ 660
           VSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQ
Sbjct: 601 VSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQ 660

Query: 661 LAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFG 720
           LAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFG
Sbjct: 661 LAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFG 720

Query: 721 ASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM 780
           ASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM
Sbjct: 721 ASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM 780

Query: 781 ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDH 840
           ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDH
Sbjct: 781 ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDH 840

Query: 841 KVCASERPPKDLGYMYFYRRIPS 863
           KVCASERPPKDLGYMYFYRRIPS
Sbjct: 841 KVCASERPPKDLGYMYFYRRIPS 863


>gi|148727247 ubiquitin specific peptidase 5 isoform 2 [Homo
           sapiens]
          Length = 835

 Score = 1071 bits (2770), Expect = 0.0
 Identities = 516/848 (60%), Positives = 665/848 (78%), Gaps = 29/848 (3%)

Query: 26  ELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEGGLYVCMNTFLAFGREHVERHFRKTG 85
           E L+  +PTIRVP++GDRV+K+ECAFS+D+P SEGGLY+CMNTFL FG+++VERHF KTG
Sbjct: 7   EALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVERHFNKTG 66

Query: 86  QSVYMHLKRHVREKVRGASGGA--LPKRRNSKIFLDLDTDDDLNSDDYEYEDEAKLVIFP 143
           Q VY+HL+R  R K    + G    P+++ +++ + ++   DL+ + +E +++ K+VI P
Sbjct: 67  QRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVILP 126

Query: 144 DHYEIALPNIEELPALV----TIACDAVLSSKSPYRKQDPDTWENEL-PVSKYANNLTQL 198
           D+ EIA   +  LP +V    T A +A+LS+ S  RKQ+   W+ E+  VSK+A +L QL
Sbjct: 127 DYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQL 186

Query: 199 DNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHYRDMGYPLAV 258
           DN  RIPP GWKC++CD+RENLWLNLTDGS+LCG+ +FD SGGN HA+EHYR+ GYPLAV
Sbjct: 187 DNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAV 246

Query: 259 KLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKL--RVSE 316
           KLGTITPDGADVYS+ E++ VLDP LA+HL+HFGIDML M  T+  + + +I +  R+ E
Sbjct: 247 KLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGE 306

Query: 317 WEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSP 376
           WE+IQESG  LKP++GPGYTG++NLGNSCYL+SV+Q +FSIP+FQR YV  L +IF  +P
Sbjct: 307 WELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAP 366

Query: 377 LDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKS 436
            DPTQDF+TQ+ KLGHGLLSG+YSKP  +S   E+V   E K  Q+GI+PRMFKA + K 
Sbjct: 367 TDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERV--PEQKEVQDGIAPRMFKALIGKG 424

Query: 437 HPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKVRYTERVD 496
           HPEFS+NRQQDAQEFFLHL+N+VERN   SENP++VFRFLVEE+I+C  T KV+YT+RVD
Sbjct: 425 HPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD 484

Query: 497 YLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDD 556
           Y+MQLPV M+AA NK+EL+ YE  +R+AE  +  LPELVRA++PFS+CL+A+  PE VDD
Sbjct: 485 YIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDD 544

Query: 557 FWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMPDLLDINHLRA 616
           FWS+ALQAKS  VKT+RFASFP+YLV+QIKKFTFGLDWVPKK DVSI+MP+ LDI+ LR 
Sbjct: 545 FWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRG 604

Query: 617 RGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQLAEMGFPLEACRKAVY 676
            GLQPGEEELPDI+PP+V PD+ K  +         +DES ++QL EMGFP++ACRKAVY
Sbjct: 605 TGLQPGEEELPDIAPPLVTPDEPKAPM---------LDESVIIQLVEMGFPMDACRKAVY 655

Query: 677 FTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFGASGLDNQPPEEIVAII 736
           +TGN GAE A NW++ HM++PDFA PL +PG  G  S  A+        + PPE+ V  I
Sbjct: 656 YTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA-------DPPPEDCVTTI 708

Query: 737 TSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM-ENNANANIISEAKPE 795
            SMGF R+QA++ALRATNN+LERA+DWIFSH + + D++  +++ E  + A+ ISE+ P 
Sbjct: 709 VSMGFSRDQALKALRATNNSLERAVDWIFSHID-DLDAEAAMDISEGRSAADSISESVPV 767

Query: 796 GPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHKVCASERPPKDLGYM 855
           GP+V+DG G Y+LFAFISHMGTSTM GHY+CHIKKEGRWVIYND KVCASE+PPKDLGY+
Sbjct: 768 GPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCASEKPPKDLGYI 827

Query: 856 YFYRRIPS 863
           YFY+R+ S
Sbjct: 828 YFYQRVAS 835


>gi|148727331 ubiquitin specific peptidase 5 isoform 1 [Homo
           sapiens]
          Length = 858

 Score = 1068 bits (2762), Expect = 0.0
 Identities = 518/862 (60%), Positives = 667/862 (77%), Gaps = 34/862 (3%)

Query: 26  ELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEGGLYVCMNTFLAFGREHVERHFRKTG 85
           E L+  +PTIRVP++GDRV+K+ECAFS+D+P SEGGLY+CMNTFL FG+++VERHF KTG
Sbjct: 7   EALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVERHFNKTG 66

Query: 86  QSVYMHLKRHVREKVRGASGGA--LPKRRNSKIFLDLDTDDDLNSDDYEYEDEAKLVIFP 143
           Q VY+HL+R  R K    + G    P+++ +++ + ++   DL+ + +E +++ K+VI P
Sbjct: 67  QRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVILP 126

Query: 144 DHYEIALPNIEELPALV----TIACDAVLSSKSPYRKQDPDTWENEL-PVSKYANNLTQL 198
           D+ EIA   +  LP +V    T A +A+LS+ S  RKQ+   W+ E+  VSK+A +L QL
Sbjct: 127 DYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQL 186

Query: 199 DNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHYRDMGYPLAV 258
           DN  RIPP GWKC++CD+RENLWLNLTDGS+LCG+ +FD SGGN HA+EHYR+ GYPLAV
Sbjct: 187 DNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAV 246

Query: 259 KLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKL--RVSE 316
           KLGTITPDGADVYS+ E++ VLDP LA+HL+HFGIDML M  T+  + + +I +  R+ E
Sbjct: 247 KLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGE 306

Query: 317 WEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSP 376
           WE+IQESG  LKP++GPGYTG++NLGNSCYL+SV+Q +FSIP+FQR YV  L +IF  +P
Sbjct: 307 WELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAP 366

Query: 377 LDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKS 436
            DPTQDF+TQ+ KLGHGLLSG+YSKP  +S   E+V   E K  Q+GI+PRMFKA + K 
Sbjct: 367 TDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERV--PEQKEVQDGIAPRMFKALIGKG 424

Query: 437 HPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKVRYTERVD 496
           HPEFS+NRQQDAQEFFLHL+N+VERN   SENP++VFRFLVEE+I+C  T KV+YT+RVD
Sbjct: 425 HPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD 484

Query: 497 YLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDD 556
           Y+MQLPV M+AA NK+EL+ YE  +R+AE  +  LPELVRA++PFS+CL+A+  PE VDD
Sbjct: 485 YIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDD 544

Query: 557 FWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMPDLLDINHLRA 616
           FWS+ALQAKS  VKT+RFASFP+YLV+QIKKFTFGLDWVPKK DVSI+MP+ LDI+ LR 
Sbjct: 545 FWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRG 604

Query: 617 RGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSD--------------IDESSVMQLA 662
            GLQPGEEELPDI+PP+V PD+ K  L     +  D              +DES ++QL 
Sbjct: 605 TGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLV 664

Query: 663 EMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFGAS 722
           EMGFP++ACRKAVY+TGN GAE A NW++ HM++PDFA PL +PG  G  S  A+     
Sbjct: 665 EMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA---- 720

Query: 723 GLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM-E 781
              + PPE+ V  I SMGF R+QA++ALRATNN+LERA+DWIFSH + + D++  +++ E
Sbjct: 721 ---DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHID-DLDAEAAMDISE 776

Query: 782 NNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHK 841
             + A+ ISE+ P GP+V+DG G Y+LFAFISHMGTSTM GHY+CHIKKEGRWVIYND K
Sbjct: 777 GRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQK 836

Query: 842 VCASERPPKDLGYMYFYRRIPS 863
           VCASE+PPKDLGY+YFY+R+ S
Sbjct: 837 VCASEKPPKDLGYIYFYQRVAS 858


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 79/297 (26%), Positives = 125/297 (42%), Gaps = 47/297 (15%)

Query: 327  LKPMYG---PGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDF 383
            L P++G   P  TGL+NLGN+CY++S++Q +            N P + DY   +  QD 
Sbjct: 765  LNPVFGGSGPALTGLRNLGNTCYMNSILQCLC-----------NAPHLADYFNRNCYQDD 813

Query: 384  NTQMTKLGHGLLSGQYSKPPVKSELIEQ---VMKEEHKPQQNGISPRMFKAFVSKSHPEF 440
              +   LGH            K E+ E+   +MK     Q   ISP+ FK  + K + +F
Sbjct: 814  INRSNLLGH------------KGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQF 861

Query: 441  SSNRQQDAQEFFLHLVNLV--------ERNRIGSENPSDVFRFLVEERIQCCQTRKVRYT 492
            +   QQD+QE  L L++ +         R R   EN   +  F   E     Q  K    
Sbjct: 862  AGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAE--HAWQKHKQLNE 919

Query: 493  ERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPE 552
              +  L Q     +  +    L  ++ +R         LP    +K     CL+ FS+ E
Sbjct: 920  SIIVALFQ----GQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEE 975

Query: 553  NVDD---FWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMP 606
             + D   F+ S  +A+   +K       P  L+V +K+F++   W  +K   S+D P
Sbjct: 976  KLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFP 1031


>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 79/297 (26%), Positives = 125/297 (42%), Gaps = 47/297 (15%)

Query: 327  LKPMYG---PGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDF 383
            L P++G   P  TGL+NLGN+CY++S++Q +            N P + DY   +  QD 
Sbjct: 765  LNPVFGGSGPALTGLRNLGNTCYMNSILQCLC-----------NAPHLADYFNRNCYQDD 813

Query: 384  NTQMTKLGHGLLSGQYSKPPVKSELIEQ---VMKEEHKPQQNGISPRMFKAFVSKSHPEF 440
              +   LGH            K E+ E+   +MK     Q   ISP+ FK  + K + +F
Sbjct: 814  INRSNLLGH------------KGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQF 861

Query: 441  SSNRQQDAQEFFLHLVNLV--------ERNRIGSENPSDVFRFLVEERIQCCQTRKVRYT 492
            +   QQD+QE  L L++ +         R R   EN   +  F   E     Q  K    
Sbjct: 862  AGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAE--HAWQKHKQLNE 919

Query: 493  ERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPE 552
              +  L Q     +  +    L  ++ +R         LP    +K     CL+ FS+ E
Sbjct: 920  SIIVALFQ----GQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEE 975

Query: 553  NVDD---FWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMP 606
             + D   F+ S  +A+   +K       P  L+V +K+F++   W  +K   S+D P
Sbjct: 976  KLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFP 1031


>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 79/297 (26%), Positives = 125/297 (42%), Gaps = 47/297 (15%)

Query: 327  LKPMYG---PGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDF 383
            L P++G   P  TGL+NLGN+CY++S++Q +            N P + DY   +  QD 
Sbjct: 765  LNPVFGGSGPALTGLRNLGNTCYMNSILQCLC-----------NAPHLADYFNRNCYQDD 813

Query: 384  NTQMTKLGHGLLSGQYSKPPVKSELIEQ---VMKEEHKPQQNGISPRMFKAFVSKSHPEF 440
              +   LGH            K E+ E+   +MK     Q   ISP+ FK  + K + +F
Sbjct: 814  INRSNLLGH------------KGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQF 861

Query: 441  SSNRQQDAQEFFLHLVNLV--------ERNRIGSENPSDVFRFLVEERIQCCQTRKVRYT 492
            +   QQD+QE  L L++ +         R R   EN   +  F   E     Q  K    
Sbjct: 862  AGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAE--HAWQKHKQLNE 919

Query: 493  ERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPE 552
              +  L Q     +  +    L  ++ +R         LP    +K     CL+ FS+ E
Sbjct: 920  SIIVALFQ----GQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEE 975

Query: 553  NVDD---FWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMP 606
             + D   F+ S  +A+   +K       P  L+V +K+F++   W  +K   S+D P
Sbjct: 976  KLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFP 1031


>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
          Length = 520

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 94/451 (20%), Positives = 173/451 (38%), Gaps = 93/451 (20%)

Query: 206 PSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHYRDMGYPLAVKLGTITP 265
           PS W C+ C   ++ W+ LT  SV CG++       NGHA +HY D   PL     +   
Sbjct: 24  PSSWCCSVCRSNKSPWVCLTCSSVHCGRYV------NGHAKKHYEDAQVPLTNHKKSEKQ 77

Query: 266 DGAD-----------VYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKLRV 314
           D               Y ++ ++ V++      L        H+   EN     D   R 
Sbjct: 78  DKVQHTVCMDCSSYSTYCYRCDDFVVND---TKLGLVQKVREHLQNLENSAFTAD---RH 131

Query: 315 SEWEVIQESGTKLKPMYGPGYT------GLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNL 368
            + ++++ S    K +   G T      GL+NLGN+C++++++Q++ +I +F   Y   L
Sbjct: 132 KKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQF-CCYFKEL 190

Query: 369 PRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRM 428
           P +         ++  T   +  H    G  +   V  E   + +    +  Q   SP  
Sbjct: 191 PAV-------ELRNGKTAGRRTYHTRSQGDNNVSLV--EEFRKTLCALWQGSQTAFSPES 241

Query: 429 FKAFVSKSHPEFSSNRQQDAQEFFLHLV-----------NLVERNRIGSENP-------- 469
               V K  P F   +QQDA EF  +L+           N V R+ I  EN         
Sbjct: 242 LFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKC 301

Query: 470 ---------SDVFRFLVEERIQC--CQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYE 518
                    + +F  +++  + C  C T   ++   +D  + +P    +  +K++     
Sbjct: 302 CINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPV 361

Query: 519 LTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDD---FWSSALQAKSAGVKTSRFA 575
            + R+                    CL++F++ E +D+   +     + K    K     
Sbjct: 362 CSLRD--------------------CLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQ 401

Query: 576 SFPEYLVVQIKKFTFGLDWVPKKFDVSIDMP 606
             P+ L + +K+F +   ++  K D  ++ P
Sbjct: 402 KLPKVLCLHLKRFHW-TAYLRNKVDTYVEFP 431



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 6/70 (8%)

Query: 791 EAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHKVCAS--ERP 848
           E +  GP     S  Y+L A + H G+   SGHY  +   EGRW  +ND  V  +  E  
Sbjct: 443 EPENSGPE----SCLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETV 498

Query: 849 PKDLGYMYFY 858
            K   Y+ FY
Sbjct: 499 VKAKAYILFY 508


>gi|55770884 ubiquitin associated domain containing 1 [Homo sapiens]
          Length = 405

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 44/148 (29%), Positives = 64/148 (43%), Gaps = 31/148 (20%)

Query: 645 NQLIDPSD---IDESSVMQLAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAE 701
           N ++D  +   +DE+++ QL EMGFP     KA+    +M    A  W+I H E+P    
Sbjct: 181 NAMLDEDEDERVDEAALRQLTEMGFPENRATKALQLN-HMSVPQAMEWLIEHAEDPTIDT 239

Query: 702 PLTMPGY------GGAASAGASVFGASGLDNQPPEEIVAI-------------------I 736
           PL  PG       G  A+A  +  GAS  D +  +E+  I                   +
Sbjct: 240 PL--PGQAPPEAEGATAAASEAAAGASATDEEARDELTEIFKKIRRKREFRADARAVISL 297

Query: 737 TSMGFQRNQAIQALRATNNNLERALDWI 764
             MGF   + I ALR  NN    A +W+
Sbjct: 298 MEMGFDEKEVIDALRVNNNQQNAACEWL 325



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 14/45 (31%), Positives = 27/45 (60%)

Query: 725 DNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPE 769
           D +  E  +  +T MGF  N+A +AL+  + ++ +A++W+  H E
Sbjct: 189 DERVDEAALRQLTEMGFPENRATKALQLNHMSVPQAMEWLIEHAE 233


>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
          Length = 565

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 70/301 (23%), Positives = 115/301 (38%), Gaps = 47/301 (15%)

Query: 330 MYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTK 389
           + G G+ GL+NLGN+C+L++V+Q + S    +   +               +DF  ++  
Sbjct: 206 LLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCL--------------RRDFRQEVPG 251

Query: 390 LGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQ 449
            G            +     + +    H      ++P  F+A   K  P FS   QQDAQ
Sbjct: 252 GGRA--------QELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQ 303

Query: 450 EFFLHLVNL--VERNRIGSENPSDVFR-----------FLVEERIQCCQTRK----VRYT 492
           EF   L+    +E NR G   P  +              L+EE       R      RY 
Sbjct: 304 EFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYL 363

Query: 493 ERVD-YLMQLPVAMEAATNKDELIAYELTRREAEAN-RRPLPE--LVRAKIPFSACLQAF 548
           ER D  ++ L V    +  K +   Y  T  E   +   P+P+      K+    C   F
Sbjct: 364 EREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLF 423

Query: 549 SEPENVDDFWS---SALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDM 605
           ++ E ++   +      + K+   K      FP  LV+ + +F+     + KK  V +D 
Sbjct: 424 TKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSI-KKSSVGVDF 482

Query: 606 P 606
           P
Sbjct: 483 P 483



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 3/62 (4%)

Query: 800 KDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHKV--CASERPPKDLGYMYF 857
           K GS  Y+L+A  +H G S   GHY    + +  W +YND +V   +  +     GY+ F
Sbjct: 496 KAGSPVYQLYALCNHSG-SVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLF 554

Query: 858 YR 859
           Y+
Sbjct: 555 YQ 556


>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
          Length = 565

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 70/301 (23%), Positives = 115/301 (38%), Gaps = 47/301 (15%)

Query: 330 MYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTK 389
           + G G+ GL+NLGN+C+L++V+Q + S    +   +               +DF  ++  
Sbjct: 206 LLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCL--------------RRDFRQEVPG 251

Query: 390 LGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQ 449
            G            +     + +    H      ++P  F+A   K  P FS   QQDAQ
Sbjct: 252 GGRA--------QELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQ 303

Query: 450 EFFLHLVNL--VERNRIGSENPSDVFR-----------FLVEERIQCCQTRK----VRYT 492
           EF   L+    +E NR G   P  +              L+EE       R      RY 
Sbjct: 304 EFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYL 363

Query: 493 ERVD-YLMQLPVAMEAATNKDELIAYELTRREAEAN-RRPLPE--LVRAKIPFSACLQAF 548
           ER D  ++ L V    +  K +   Y  T  E   +   P+P+      K+    C   F
Sbjct: 364 EREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLF 423

Query: 549 SEPENVDDFWS---SALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDM 605
           ++ E ++   +      + K+   K      FP  LV+ + +F+     + KK  V +D 
Sbjct: 424 TKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSI-KKSSVGVDF 482

Query: 606 P 606
           P
Sbjct: 483 P 483



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 3/62 (4%)

Query: 800 KDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHKV--CASERPPKDLGYMYF 857
           K GS  Y+L+A  +H G S   GHY    + +  W +YND +V   +  +     GY+ F
Sbjct: 496 KAGSPVYQLYALCNHSG-SVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLF 554

Query: 858 YR 859
           Y+
Sbjct: 555 YQ 556


>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
          Length = 952

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 20/125 (16%)

Query: 333 PGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGH 392
           PG  GL NLGN+C+++S +Q +            N P + +Y   D  Q+       LG 
Sbjct: 257 PGLCGLSNLGNTCFMNSAIQCL-----------SNTPPLTEYFLNDKYQEELNFDNPLG- 304

Query: 393 GLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEFF 452
             + G+ +K    +ELI+Q+   +     + ++PR FK  V +  P+FS  +QQD QE  
Sbjct: 305 --MRGEIAKS--YAELIKQMWSGKF----SYVTPRAFKTQVGRFAPQFSGYQQQDCQELL 356

Query: 453 LHLVN 457
             L++
Sbjct: 357 AFLLD 361


>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
          Length = 712

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 50/195 (25%), Positives = 78/195 (40%), Gaps = 42/195 (21%)

Query: 309 DIKLRVSEWEVIQ---ESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYV 365
           D  L  SE E+ Q   +S  K +P+  PG TGL+NLGN+CY++SV+Q +  +  F++ ++
Sbjct: 243 DKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFL 302

Query: 366 ------------GNLPRIFDYSPLDPT--------QDFNTQMTKLGHGLLSGQYSKPPVK 405
                           R   + P+  T        Q+ +T         LS   S    K
Sbjct: 303 KLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASK 362

Query: 406 SELIEQVMKEEHKPQQNG-------------------ISPRMFKAFVSKSHPEFSSNRQQ 446
              +E +  +E   Q                      +SP      V +  P F    QQ
Sbjct: 363 GRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQ 422

Query: 447 DAQEFFLHLVNLVER 461
           DAQEF   L++ ++R
Sbjct: 423 DAQEFLCELLDKIQR 437



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 18/71 (25%), Positives = 37/71 (52%), Gaps = 6/71 (8%)

Query: 190 KYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHY 249
           K+   L    +   + P  W C  C+  E++W  L+   V CG++  +      HAL+H+
Sbjct: 8   KHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEE------HALKHF 61

Query: 250 RDMGYPLAVKL 260
           ++  +P+A+++
Sbjct: 62  QESSHPVALEV 72



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 19/108 (17%)

Query: 755 NNLERALDWIFSHPEFEEDSDFVIEMENNANANIISEAKPEGPRVKDGSGTYELFAFISH 814
           NN E+    I  H  FEE    ++ ME       +   +PE          Y+L A + H
Sbjct: 583 NNREK----IGVHVGFEE----ILNMEPYCCRETLKSLRPE-------CFIYDLSAVVMH 627

Query: 815 MGTSTMSGHY--ICHIKKEGRWVIYNDHK--VCASERPPKDLGYMYFY 858
            G    SGHY   C+  + G WV  ND K  +C  +   K   Y+ FY
Sbjct: 628 HGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFY 675


>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
          Length = 712

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 50/195 (25%), Positives = 78/195 (40%), Gaps = 42/195 (21%)

Query: 309 DIKLRVSEWEVIQ---ESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYV 365
           D  L  SE E+ Q   +S  K +P+  PG TGL+NLGN+CY++SV+Q +  +  F++ ++
Sbjct: 243 DKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFL 302

Query: 366 ------------GNLPRIFDYSPLDPT--------QDFNTQMTKLGHGLLSGQYSKPPVK 405
                           R   + P+  T        Q+ +T         LS   S    K
Sbjct: 303 KLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASK 362

Query: 406 SELIEQVMKEEHKPQQNG-------------------ISPRMFKAFVSKSHPEFSSNRQQ 446
              +E +  +E   Q                      +SP      V +  P F    QQ
Sbjct: 363 GRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQ 422

Query: 447 DAQEFFLHLVNLVER 461
           DAQEF   L++ ++R
Sbjct: 423 DAQEFLCELLDKIQR 437



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 18/71 (25%), Positives = 37/71 (52%), Gaps = 6/71 (8%)

Query: 190 KYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHY 249
           K+   L    +   + P  W C  C+  E++W  L+   V CG++  +      HAL+H+
Sbjct: 8   KHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEE------HALKHF 61

Query: 250 RDMGYPLAVKL 260
           ++  +P+A+++
Sbjct: 62  QESSHPVALEV 72



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 19/108 (17%)

Query: 755 NNLERALDWIFSHPEFEEDSDFVIEMENNANANIISEAKPEGPRVKDGSGTYELFAFISH 814
           NN E+    I  H  FEE    ++ ME       +   +PE          Y+L A + H
Sbjct: 583 NNREK----IGVHVGFEE----ILNMEPYCCRETLKSLRPE-------CFIYDLSAVVMH 627

Query: 815 MGTSTMSGHY--ICHIKKEGRWVIYNDHK--VCASERPPKDLGYMYFY 858
            G    SGHY   C+  + G WV  ND K  +C  +   K   Y+ FY
Sbjct: 628 HGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFY 675


>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
          Length = 963

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 24/127 (18%)

Query: 333 PGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGH 392
           PG  GL NLGN+C+++S +Q +            N   + DY   D  +    +   LG 
Sbjct: 299 PGLCGLGNLGNTCFMNSALQCL-----------SNTAPLTDYFLKDEYEAEINRDNPLG- 346

Query: 393 GLLSGQYSKPPVKSELIEQVM--KEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQE 450
             + G+ ++    +ELI+Q+   ++ H      ++PRMFK  V +  P+FS  +QQD+QE
Sbjct: 347 --MKGEIAE--AYAELIKQMWSGRDAH------VAPRMFKTQVGRFAPQFSGYQQQDSQE 396

Query: 451 FFLHLVN 457
               L++
Sbjct: 397 LLAFLLD 403


>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
          Length = 916

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 24/127 (18%)

Query: 333 PGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGH 392
           PG  GL NLGN+C+++S +Q +            N   + DY   D  +    +   LG 
Sbjct: 252 PGLCGLGNLGNTCFMNSALQCL-----------SNTAPLTDYFLKDEYEAEINRDNPLG- 299

Query: 393 GLLSGQYSKPPVKSELIEQVM--KEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQE 450
             + G+ ++    +ELI+Q+   ++ H      ++PRMFK  V +  P+FS  +QQD+QE
Sbjct: 300 --MKGEIAE--AYAELIKQMWSGRDAH------VAPRMFKTQVGRFAPQFSGYQQQDSQE 349

Query: 451 FFLHLVN 457
               L++
Sbjct: 350 LLAFLLD 356


>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
          Length = 828

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 66/260 (25%), Positives = 106/260 (40%), Gaps = 48/260 (18%)

Query: 211 CARCDLR-ENLWLNLTD--GSVLCGKWFFDSSGGNGHALEHYRDMGYPLAVKLGTITPDG 267
           C  C ++  NLW  L +    V CG+   D S  +    +HY      L V L T+    
Sbjct: 61  CQDCKVQGPNLWACLENRCSYVGCGESQVDHSTIHSQETKHY------LTVNLTTLR--- 111

Query: 268 ADVYSFQ-EEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKLR-------VSEWEV 319
             V+ +   +E  LD  L    +   +   H    EN +QD  I          V+ ++ 
Sbjct: 112 --VWCYACSKEVFLDRKLGTQPSLPHVRQPHQI-QENSVQDFKIPSNTTLKTPLVAVFDD 168

Query: 320 IQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDP 379
           +     +   +   G TGLKN+GN+CY+++ +QA+ + P                 PL  
Sbjct: 169 LDIEADEEDELRARGLTGLKNIGNTCYMNAALQALSNCP-----------------PL-- 209

Query: 380 TQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPE 439
           TQ F      L  G L+    KP +    ++ + +  HK +   + P      +   +P 
Sbjct: 210 TQFF------LDCGGLARTDKKPAICKSYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPT 263

Query: 440 FSSNRQQDAQEFFLHLVNLV 459
           F    QQDAQEF   L++L+
Sbjct: 264 FRGYSQQDAQEFLRCLMDLL 283


>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
          Length = 942

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 66/260 (25%), Positives = 106/260 (40%), Gaps = 48/260 (18%)

Query: 211 CARCDLR-ENLWLNLTD--GSVLCGKWFFDSSGGNGHALEHYRDMGYPLAVKLGTITPDG 267
           C  C ++  NLW  L +    V CG+   D S  +    +HY      L V L T+    
Sbjct: 61  CQDCKVQGPNLWACLENRCSYVGCGESQVDHSTIHSQETKHY------LTVNLTTLR--- 111

Query: 268 ADVYSFQ-EEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKLR-------VSEWEV 319
             V+ +   +E  LD  L    +   +   H    EN +QD  I          V+ ++ 
Sbjct: 112 --VWCYACSKEVFLDRKLGTQPSLPHVRQPHQI-QENSVQDFKIPSNTTLKTPLVAVFDD 168

Query: 320 IQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDP 379
           +     +   +   G TGLKN+GN+CY+++ +QA+ + P                 PL  
Sbjct: 169 LDIEADEEDELRARGLTGLKNIGNTCYMNAALQALSNCP-----------------PL-- 209

Query: 380 TQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPE 439
           TQ F      L  G L+    KP +    ++ + +  HK +   + P      +   +P 
Sbjct: 210 TQFF------LDCGGLARTDKKPAICKSYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPT 263

Query: 440 FSSNRQQDAQEFFLHLVNLV 459
           F    QQDAQEF   L++L+
Sbjct: 264 FRGYSQQDAQEFLRCLMDLL 283


>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
          Length = 911

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 66/260 (25%), Positives = 106/260 (40%), Gaps = 48/260 (18%)

Query: 211 CARCDLR-ENLWLNLTD--GSVLCGKWFFDSSGGNGHALEHYRDMGYPLAVKLGTITPDG 267
           C  C ++  NLW  L +    V CG+   D S  +    +HY      L V L T+    
Sbjct: 30  CQDCKVQGPNLWACLENRCSYVGCGESQVDHSTIHSQETKHY------LTVNLTTLR--- 80

Query: 268 ADVYSFQ-EEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKLR-------VSEWEV 319
             V+ +   +E  LD  L    +   +   H    EN +QD  I          V+ ++ 
Sbjct: 81  --VWCYACSKEVFLDRKLGTQPSLPHVRQPHQI-QENSVQDFKIPSNTTLKTPLVAVFDD 137

Query: 320 IQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDP 379
           +     +   +   G TGLKN+GN+CY+++ +QA+ + P                 PL  
Sbjct: 138 LDIEADEEDELRARGLTGLKNIGNTCYMNAALQALSNCP-----------------PL-- 178

Query: 380 TQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPE 439
           TQ F      L  G L+    KP +    ++ + +  HK +   + P      +   +P 
Sbjct: 179 TQFF------LDCGGLARTDKKPAICKSYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPT 232

Query: 440 FSSNRQQDAQEFFLHLVNLV 459
           F    QQDAQEF   L++L+
Sbjct: 233 FRGYSQQDAQEFLRCLMDLL 252


>gi|21361517 UBX domain protein 1 [Homo sapiens]
          Length = 312

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 22/51 (43%), Positives = 31/51 (60%)

Query: 656 SSVMQLAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMP 706
           +++  L EMGFP     KA+  TGN G E A +W++ H ++PD  EPL  P
Sbjct: 5   TALESLIEMGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETP 55



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 4/41 (9%)

Query: 736 ITSMGFQRNQAIQALRATNNN-LERALDWIFSHPEFEEDSD 775
           +  MGF R +A +AL  T N  +E A+DW+  H   E+D D
Sbjct: 10  LIEMGFPRGRAEKALALTGNQGIEAAMDWLMEH---EDDPD 47


>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
          Length = 1352

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 13/131 (9%)

Query: 333 PGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPL-DPTQDFNTQMTKLG 391
           PG  GL+N GN+C++++ +Q + +   F         R     P  DP Q         G
Sbjct: 125 PGVAGLRNHGNTCFMNATLQCLSNTELFAEYLALGQYRAGRPEPSPDPEQP-------AG 177

Query: 392 HGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEF 451
            G   GQ       + L+  +   E+ PQ +    R FK  VSK+  ++  N Q DAQEF
Sbjct: 178 RGA-QGQGEVTEQLAHLVRALWTLEYTPQHS----RDFKTIVSKNALQYRGNSQHDAQEF 232

Query: 452 FLHLVNLVERN 462
            L L++ V  +
Sbjct: 233 LLWLLDRVHED 243


>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
          Length = 914

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 65/251 (25%), Positives = 97/251 (38%), Gaps = 43/251 (17%)

Query: 211 CARCDLR-ENLW--LNLTDGSVLCGKWFFDSSGGNGHALEHYRDMGYPLAVKLGTITPDG 267
           C  C +   NLW  L +    V CG+ F D S  +  A +H       L V L T     
Sbjct: 30  CQSCGVTGPNLWACLQVACPYVGCGESFADHSTIHAQAKKHN------LTVNLTTFR--- 80

Query: 268 ADVYSFQ-EEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKLRVSEWEVIQESGTK 326
             ++ +  E+E  L+  LA  L                     + + V++    +     
Sbjct: 81  --LWCYACEKEVFLEQRLAAPLLGSSSKFSEQDSPPPSHPLKAVPIAVADEGESESEDDD 138

Query: 327 LKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQ 386
           LKP    G TG+KNLGNSCY+++ +QA+ + P                 PL  TQ F   
Sbjct: 139 LKPR---GLTGMKNLGNSCYMNAALQALSNCP-----------------PL--TQFF--- 173

Query: 387 MTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQ 446
              L  G L     KP +     + V +  HK + + + P      +   +P F    QQ
Sbjct: 174 ---LECGGLVRTDKKPALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQ 230

Query: 447 DAQEFFLHLVN 457
           D QEF   L++
Sbjct: 231 DTQEFLRCLMD 241


>gi|183397136 ubiquitin specific protease 20 [Homo sapiens]
          Length = 914

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 65/251 (25%), Positives = 97/251 (38%), Gaps = 43/251 (17%)

Query: 211 CARCDLR-ENLW--LNLTDGSVLCGKWFFDSSGGNGHALEHYRDMGYPLAVKLGTITPDG 267
           C  C +   NLW  L +    V CG+ F D S  +  A +H       L V L T     
Sbjct: 30  CQSCGVTGPNLWACLQVACPYVGCGESFADHSTIHAQAKKHN------LTVNLTTFR--- 80

Query: 268 ADVYSFQ-EEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKLRVSEWEVIQESGTK 326
             ++ +  E+E  L+  LA  L                     + + V++    +     
Sbjct: 81  --LWCYACEKEVFLEQRLAAPLLGSSSKFSEQDSPPPSHPLKAVPIAVADEGESESEDDD 138

Query: 327 LKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQ 386
           LKP    G TG+KNLGNSCY+++ +QA+ + P                 PL  TQ F   
Sbjct: 139 LKPR---GLTGMKNLGNSCYMNAALQALSNCP-----------------PL--TQFF--- 173

Query: 387 MTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQ 446
              L  G L     KP +     + V +  HK + + + P      +   +P F    QQ
Sbjct: 174 ---LECGGLVRTDKKPALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQ 230

Query: 447 DAQEFFLHLVN 457
           D QEF   L++
Sbjct: 231 DTQEFLRCLMD 241


>gi|183397134 ubiquitin specific protease 20 [Homo sapiens]
          Length = 914

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 65/251 (25%), Positives = 97/251 (38%), Gaps = 43/251 (17%)

Query: 211 CARCDLR-ENLW--LNLTDGSVLCGKWFFDSSGGNGHALEHYRDMGYPLAVKLGTITPDG 267
           C  C +   NLW  L +    V CG+ F D S  +  A +H       L V L T     
Sbjct: 30  CQSCGVTGPNLWACLQVACPYVGCGESFADHSTIHAQAKKHN------LTVNLTTFR--- 80

Query: 268 ADVYSFQ-EEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKLRVSEWEVIQESGTK 326
             ++ +  E+E  L+  LA  L                     + + V++    +     
Sbjct: 81  --LWCYACEKEVFLEQRLAAPLLGSSSKFSEQDSPPPSHPLKAVPIAVADEGESESEDDD 138

Query: 327 LKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQ 386
           LKP    G TG+KNLGNSCY+++ +QA+ + P                 PL  TQ F   
Sbjct: 139 LKPR---GLTGMKNLGNSCYMNAALQALSNCP-----------------PL--TQFF--- 173

Query: 387 MTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQ 446
              L  G L     KP +     + V +  HK + + + P      +   +P F    QQ
Sbjct: 174 ---LECGGLVRTDKKPALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQ 230

Query: 447 DAQEFFLHLVN 457
           D QEF   L++
Sbjct: 231 DTQEFLRCLMD 241


>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
          Length = 711

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 40/173 (23%), Positives = 76/173 (43%), Gaps = 30/173 (17%)

Query: 294 DMLHMHGTENGLQDNDIKLRVSEWE---VIQESGTKLKPMYGPGYTGLKNLGNSCYLSSV 350
           D+ H     +G +D        E E   V  +   + K +Y  G  GL NLGN+C+++ +
Sbjct: 318 DVSHQQFMTSGFEDKQSTCETKEQEPKLVKPKKKRRKKSVYTVGLRGLINLGNTCFMNCI 377

Query: 351 MQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIE 410
           +QA+  IP  +  ++ +  +    S   P+     +M+ L H + SG  + P +  +L+ 
Sbjct: 378 VQALTHIPLLKDFFLSDKHKCIMTS---PSLCLVCEMSSLFHAMYSGSRT-PHIPYKLLH 433

Query: 411 QV-MKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERN 462
            + +  EH                       +  RQQDA EF + +++++ R+
Sbjct: 434 LIWIHAEH----------------------LAGYRQQDAHEFLIAILDVLHRH 464



 Score = 30.0 bits (66), Expect = 9.6
 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 8/60 (13%)

Query: 806 YELFAFISHMGTSTMSGHYICHIKKE-GRWVIYNDHKVCASERPPKDL----GYMYFYRR 860
           Y LFA I+H GT   SGHY   I+++  +W   +D     ++   +DL    GY+ FY +
Sbjct: 649 YSLFAVINHHGT-LESGHYTSFIRQQKDQWFSCDD--AIITKATIEDLLYSEGYLLFYHK 705


>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
          Length = 485

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 24/56 (42%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 800 KDGSGTYELFAFISHMGTSTMSGHYICHIK--KEGRWVIYNDHKVCASERPPKDLG 853
           K GS  YEL A + H G S  SGHYI H+K  + G W  +ND  +   E     LG
Sbjct: 330 KGGSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLG 385



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 59/283 (20%), Positives = 108/283 (38%), Gaps = 53/283 (18%)

Query: 335 YTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGL 394
           + GL NLG +CY+++ +Q  F   E ++A         DY               LG G+
Sbjct: 88  FVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDY--------------MLGDGI 133

Query: 395 LSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLH 454
              +  +P    E ++ +        +  I P  F   +        + +QQDAQEF   
Sbjct: 134 QEEKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALG-----LDTGQQQDAQEFSKL 188

Query: 455 LVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKVRYTERVDYLMQLPVAMEAATNKDEL 514
            ++L+E      +NP    R +V+++  C +   V                     + +L
Sbjct: 189 FMSLLEDTLSKQKNPD--VRNIVQQQF-CGEYAYV-------------TVCNQCGRESKL 232

Query: 515 IA--YELTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDD---FWSSALQAKSAGV 569
           ++  YEL     E N       ++     + C+  F + E ++    ++    Q+K    
Sbjct: 233 LSKFYEL-----ELN-------IQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNAT 280

Query: 570 KTSRFASFPEYLVVQIKKFTFGLD-WVPKKFDVSIDMPDLLDI 611
           +  R  S P  L +Q+ +F F       KK +  I   ++LD+
Sbjct: 281 RKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDM 323


>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
          Length = 1035

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 24/56 (42%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 800 KDGSGTYELFAFISHMGTSTMSGHYICHIK--KEGRWVIYNDHKVCASERPPKDLG 853
           K GS  YEL A + H G S  SGHYI H+K  + G W  +ND  +   E     LG
Sbjct: 330 KGGSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLG 385



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 59/283 (20%), Positives = 108/283 (38%), Gaps = 53/283 (18%)

Query: 335 YTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGL 394
           + GL NLG +CY+++ +Q  F   E ++A         DY               LG G+
Sbjct: 88  FVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDY--------------MLGDGI 133

Query: 395 LSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLH 454
              +  +P    E ++ +        +  I P  F   +        + +QQDAQEF   
Sbjct: 134 QEEKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALG-----LDTGQQQDAQEFSKL 188

Query: 455 LVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKVRYTERVDYLMQLPVAMEAATNKDEL 514
            ++L+E      +NP    R +V+++  C +   V                     + +L
Sbjct: 189 FMSLLEDTLSKQKNPD--VRNIVQQQF-CGEYAYV-------------TVCNQCGRESKL 232

Query: 515 IA--YELTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDD---FWSSALQAKSAGV 569
           ++  YEL     E N       ++     + C+  F + E ++    ++    Q+K    
Sbjct: 233 LSKFYEL-----ELN-------IQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNAT 280

Query: 570 KTSRFASFPEYLVVQIKKFTFGLD-WVPKKFDVSIDMPDLLDI 611
           +  R  S P  L +Q+ +F F       KK +  I   ++LD+
Sbjct: 281 RKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDM 323


>gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens]
          Length = 1042

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 46/175 (26%), Positives = 73/175 (41%), Gaps = 47/175 (26%)

Query: 334 GYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVG-NLPRIFDYSPLDPTQDFNTQMTKLGH 392
           G TGL NLGN+CY++SV+QA+F   +F+R  +  NL               N+ M KL H
Sbjct: 443 GKTGLINLGNTCYMNSVIQALFMATDFRRQVLSLNL------------NGCNSLMKKLQH 490

Query: 393 GLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEFF 452
                 ++                   Q+   +PR+F  F +   P F+   QQD  E+ 
Sbjct: 491 LFAFLAHT-------------------QREAYAPRIF--FEASRPPWFTPRSQQDCSEYL 529

Query: 453 LHLVN-LVERNRI----GSENPSDVFRFLVEERIQCCQTRKVRYTERVDYLMQLP 502
             L++ L E  +I     S  PS++        ++C +T       +   L + P
Sbjct: 530 RFLLDRLHEEEKILKVQASHKPSEI--------LECSETSLQEVASKAAVLTETP 576


>gi|57529246 ubiquitin thioesterase 19 [Homo sapiens]
          Length = 1318

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 20/138 (14%)

Query: 320 IQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDP 379
           ++E   + K +  PG+TGL NLGN+C+++SV+Q++ +  E        L   F     + 
Sbjct: 481 VEEEEEEEKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRE--------LRDFFHDRSFEA 532

Query: 380 TQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPE 439
             ++N  +   G   +          + L+  + K  H    +   P   KA V+    +
Sbjct: 533 EINYNNPLGTGGRLAIG--------FAVLLRALWKGTH----HAFQPSKLKAIVASKASQ 580

Query: 440 FSSNRQQDAQEFFLHLVN 457
           F+   Q DAQEF   L++
Sbjct: 581 FTGYAQHDAQEFMAFLLD 598


>gi|82880645 ubiquitin specific protease 14 isoform b [Homo sapiens]
          Length = 459

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 71/337 (21%), Positives = 138/337 (40%), Gaps = 53/337 (15%)

Query: 326 KLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRA---YVGNLPRIFDYSPLDPTQD 382
           K+K M  P   GL NLGN+CY+++ +Q I S+PE + A   Y G L              
Sbjct: 62  KIKNMELP--CGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGAL-------------- 105

Query: 383 FNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSS 442
                 +    + S QY    ++ +L + + K       + I P +   F+  + P+F+ 
Sbjct: 106 ------RASGEMASAQYITAALR-DLFDSMDK-----TSSSIPPIILLQFLHMAFPQFAE 153

Query: 443 N------RQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKVRYTERVD 496
                   QQDA E ++ ++ ++++     E+  D  +             K +      
Sbjct: 154 KGEQGQYLQQDANECWIQMMRVLQQKLEAIED--DSVKETDSSSASAATPSKKKSLIDQF 211

Query: 497 YLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDD 556
           + ++    M+   +++E    E+T+   + N+  L   +  ++ +          E +  
Sbjct: 212 FGVEFETTMKCTESEEE----EVTK--GKENQLQLSCFINQEVKYLFTGLKLRLQEEITK 265

Query: 557 FWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTF-GLDWVPKKFDVSIDMPDLLDINHLR 615
             S  LQ  +  +K+S+ +  P YL +Q+ +F +   + V  K    +  P +LD+  L 
Sbjct: 266 -QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELC 324

Query: 616 ARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSD 652
              LQ   E++           D +D+ +NQ  + SD
Sbjct: 325 TPELQ---EKMVSFRSKF---KDLEDKKVNQQPNTSD 355



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%)

Query: 804 GTYELFAFISHMGTSTMSGHYICHIK-KEGRWVIYNDHKV 842
           G Y+L A ++H G S+ SGHY+  +K K+  W+ ++D KV
Sbjct: 381 GYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKV 420


>gi|4827050 ubiquitin specific protease 14 isoform a [Homo sapiens]
          Length = 494

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 67/326 (20%), Positives = 133/326 (40%), Gaps = 51/326 (15%)

Query: 337 GLKNLGNSCYLSSVMQAIFSIPEFQRA---YVGNLPRIFDYSPLDPTQDFNTQMTKLGHG 393
           GL NLGN+CY+++ +Q I S+PE + A   Y G L                    +    
Sbjct: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGAL--------------------RASGE 145

Query: 394 LLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSN------RQQD 447
           + S QY    ++ +L + + K       + I P +   F+  + P+F+         QQD
Sbjct: 146 MASAQYITAALR-DLFDSMDK-----TSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQD 199

Query: 448 AQEFFLHLVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKVRYTERVDYLMQLPVAMEA 507
           A E ++ ++ ++++     E+  D  +             K +      + ++    M+ 
Sbjct: 200 ANECWIQMMRVLQQKLEAIED--DSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKC 257

Query: 508 ATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDDFWSSALQAKSA 567
             +++E    E+T+   + N+  L   +  ++ +          E +    S  LQ  + 
Sbjct: 258 TESEEE----EVTK--GKENQLQLSCFINQEVKYLFTGLKLRLQEEITK-QSPTLQRNAL 310

Query: 568 GVKTSRFASFPEYLVVQIKKFTF-GLDWVPKKFDVSIDMPDLLDINHLRARGLQPGEEEL 626
            +K+S+ +  P YL +Q+ +F +   + V  K    +  P +LD+  L    LQ   E++
Sbjct: 311 YIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQ---EKM 367

Query: 627 PDISPPIVIPDDSKDRLMNQLIDPSD 652
                      D +D+ +NQ  + SD
Sbjct: 368 VSFRSKF---KDLEDKKVNQQPNTSD 390



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%)

Query: 804 GTYELFAFISHMGTSTMSGHYICHIK-KEGRWVIYNDHKV 842
           G Y+L A ++H G S+ SGHY+  +K K+  W+ ++D KV
Sbjct: 416 GYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKV 455


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,891,155
Number of Sequences: 37866
Number of extensions: 1697104
Number of successful extensions: 4691
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 4409
Number of HSP's gapped (non-prelim): 281
length of query: 863
length of database: 18,247,518
effective HSP length: 111
effective length of query: 752
effective length of database: 14,044,392
effective search space: 10561382784
effective search space used: 10561382784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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