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Search of human proteins with 214829673
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|214829673 ADP-ribosylation factor GTPase activating protein
3 isoform 1 [Homo sapiens]
(516 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|214829673 ADP-ribosylation factor GTPase activating protein 3... 1032 0.0
gi|214829714 ADP-ribosylation factor GTPase activating protein 3... 921 0.0
gi|31543983 ADP-ribosylation factor GTPase activating protein 2 ... 525 e-149
gi|8922652 ADP-ribosylation factor GTPase activating protein 1 i... 120 4e-27
gi|28416436 ADP-ribosylation factor GTPase activating protein 1 ... 115 7e-26
gi|23943872 small ArfGAP2 [Homo sapiens] 81 2e-15
gi|113204622 stromal membrane-associated GTPase-activating prote... 80 4e-15
gi|21264558 stromal membrane-associated GTPase-activating protei... 80 4e-15
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 79 1e-14
gi|187608516 centaurin, beta 2 [Homo sapiens] 78 2e-14
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 76 6e-14
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 74 3e-13
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 74 3e-13
gi|46094081 development and differentiation enhancing factor 1 [... 73 7e-13
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 73 7e-13
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 73 7e-13
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 70 5e-12
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 69 8e-12
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 69 1e-11
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 69 1e-11
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 69 1e-11
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 69 1e-11
gi|7661880 centaurin beta1 [Homo sapiens] 68 2e-11
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 67 3e-11
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do... 65 1e-10
gi|6806913 centaurin, alpha 1 [Homo sapiens] 65 2e-10
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 64 4e-10
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ... 64 4e-10
gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 62 1e-09
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 61 2e-09
>gi|214829673 ADP-ribosylation factor GTPase activating protein 3
isoform 1 [Homo sapiens]
Length = 516
Score = 1032 bits (2668), Expect = 0.0
Identities = 516/516 (100%), Positives = 516/516 (100%)
Query: 1 MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60
MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS
Sbjct: 1 MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60
Query: 61 FIRSTELDSNWSWFQLRCMQVGGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKIKSL 120
FIRSTELDSNWSWFQLRCMQVGGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKIKSL
Sbjct: 61 FIRSTELDSNWSWFQLRCMQVGGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKIKSL 120
Query: 121 ASQATRKHGTDLWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV 180
ASQATRKHGTDLWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV
Sbjct: 121 ASQATRKHGTDLWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV 180
Query: 181 ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANT 240
ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANT
Sbjct: 181 ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANT 240
Query: 241 CFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNV 300
CFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNV
Sbjct: 241 CFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNV 300
Query: 301 DSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEP 360
DSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEP
Sbjct: 301 DSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEP 360
Query: 361 VELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKK 420
VELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKK
Sbjct: 361 VELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKK 420
Query: 421 FGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLP 480
FGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLP
Sbjct: 421 FGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLP 480
Query: 481 NAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 516
NAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS
Sbjct: 481 NAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 516
>gi|214829714 ADP-ribosylation factor GTPase activating protein 3
isoform 2 [Homo sapiens]
Length = 472
Score = 921 bits (2381), Expect = 0.0
Identities = 472/516 (91%), Positives = 472/516 (91%), Gaps = 44/516 (8%)
Query: 1 MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60
MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS
Sbjct: 1 MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60
Query: 61 FIRSTELDSNWSWFQLRCMQVGGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKIKSL 120
FIRSTELDSNWSWFQLRCMQVGGNASA
Sbjct: 61 FIRSTELDSNWSWFQLRCMQVGGNASA--------------------------------- 87
Query: 121 ASQATRKHGTDLWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV 180
LWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV
Sbjct: 88 -----------LWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV 136
Query: 181 ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANT 240
ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANT
Sbjct: 137 ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANT 196
Query: 241 CFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNV 300
CFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNV
Sbjct: 197 CFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNV 256
Query: 301 DSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEP 360
DSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEP
Sbjct: 257 DSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEP 316
Query: 361 VELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKK 420
VELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKK
Sbjct: 317 VELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKK 376
Query: 421 FGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLP 480
FGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLP
Sbjct: 377 FGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLP 436
Query: 481 NAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 516
NAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS
Sbjct: 437 NAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 472
>gi|31543983 ADP-ribosylation factor GTPase activating protein 2
[Homo sapiens]
Length = 521
Score = 525 bits (1351), Expect = e-149
Identities = 289/529 (54%), Positives = 369/529 (69%), Gaps = 27/529 (5%)
Query: 3 DPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFI 62
+P+K +I T+FKRLR+VPTNK CFDCGAKNPSWASITYGVFLCIDCSG HRSLGVHLSFI
Sbjct: 4 EPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFI 63
Query: 63 RSTELDSNWSWFQLRCMQVGGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKIKSLAS 122
RSTELDSNW+WFQLRCMQVGGNA+A++FF QHGC+ ND N KYNSRAAQ+YREKI+ L S
Sbjct: 64 RSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGS 123
Query: 123 QATRKHGTDLWLD--SCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV 180
A +HGTDLW+D S VP SP K+ DFF H P AW + EPS T +P
Sbjct: 124 AALARHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQP----PAWDAPATEPSG-TQQPA 178
Query: 181 ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSII--KKKPNQAKKGLGAKKGSLGAQKLA 238
+T + E GP+ + L KA+LE+ S I KKKP AKKGLGAKKG LGAQK++
Sbjct: 179 PSTESSGLAQPEHGPNTDLLGTSPKASLELKSSIIGKKKPAAAKKGLGAKKG-LGAQKVS 237
Query: 239 NTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEK--MNISG 296
+ F+EIE+QAQ A+K++EQ+ EES+V+S+RLAY++L+I KK+EK N+ G
Sbjct: 238 SQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEG 297
Query: 297 KKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDD--SYFTSSS 354
KK ++RLGMG + RS +SHSV S+MQ IEQE+P+ AK + D DD ++ +
Sbjct: 298 KKREQAERLGMGLVS-RSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPP 356
Query: 355 SYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVEN- 413
Y D P L S S WD +D+ W + ++ E + T S RP + R + VE+
Sbjct: 357 KYKDNPFSLGESFGSRWD--TDAAWGMDRVEEKEP--EVTISSIRPISERATNRREVESR 412
Query: 414 -----TDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLF-EEPRK 467
+ EA++KF KAISSDM+FGR+ A+YE R+RL++LS SS+ISS+DLF +
Sbjct: 413 SSGLESSEARQKFAGAKAISSDMFFGREVDAEYEARSRLQQLSGSSAISSSDLFGDMDGA 472
Query: 468 QPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 516
AG+ SL +VLP A D+AQFKQGV+SVAGK++V ANGV+ S+QDRYGS
Sbjct: 473 HGAGSVSLGNVLPTA-DIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGS 520
>gi|8922652 ADP-ribosylation factor GTPase activating protein 1
isoform a [Homo sapiens]
Length = 406
Score = 120 bits (300), Expect = 4e-27
Identities = 116/393 (29%), Positives = 170/393 (43%), Gaps = 59/393 (15%)
Query: 12 IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNW 71
+ K +R N VCF+CGA NP W S+TYG+++C++CSG HR LGVHLSF+RS +D W
Sbjct: 9 VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD-KW 67
Query: 72 SWFQLRCMQVGGNASASSFFHQHGCSTN--DTNAKYNSRAAQLYREKIKSLASQATRKHG 129
+L M+ GGNA F KYNSRAA L+R+K+ +LA G
Sbjct: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALA------EG 121
Query: 130 TDLWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTS---RPVETTLEN 186
+ L+S +PP P + +P S+T+ + E L +
Sbjct: 122 REWSLESSPAQNWTPP-----------QPRTLPSMVHRVSGQPQSVTASSDKAFEDWLND 170
Query: 187 NEGGQE--QGPSVEGL-NVPTKATLE-------VSSI----------IKKKPNQAKKGLG 226
+ G + QG G N P E +SS+ + + AK+G
Sbjct: 171 DLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEG-A 229
Query: 227 AKKGSLGAQK---LANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLE 283
K GS +QK L ++ + K AQ +K+KE K+ S VS L + +
Sbjct: 230 TKFGSQASQKASELGHSLNENVLKPAQ--EKVKE----GKIFDDVSSGVSQLASKVQGVG 283
Query: 284 IQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYND 343
+ +D SGK D G S + H S++ E+ A+P K
Sbjct: 284 SKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKS 343
Query: 344 DSDDSYFTSSSSYFDEPVELRSS-SFSSWDDSS 375
S DS+ + +S E RSS S+ W +S
Sbjct: 344 PSSDSWTCADTS-----TERRSSDSWEVWGSAS 371
>gi|28416436 ADP-ribosylation factor GTPase activating protein 1
isoform b [Homo sapiens]
Length = 414
Score = 115 bits (289), Expect = 7e-26
Identities = 118/403 (29%), Positives = 172/403 (42%), Gaps = 71/403 (17%)
Query: 12 IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNW 71
+ K +R N VCF+CGA NP W S+TYG+++C++CSG HR LGVHLSF+RS +D W
Sbjct: 9 VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD-KW 67
Query: 72 SWFQLRCMQVGGNASASSFFHQHGCSTN--DTNAKYNSRAAQLYREKIKSLASQATRKHG 129
+L M+ GGNA F KYNSRAA L+R+K+ +LA G
Sbjct: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALA------EG 121
Query: 130 TDLWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTS---RPVETTLEN 186
+ L+S +PP P + +P S+T+ + E L +
Sbjct: 122 REWSLESSPAQNWTPP-----------QPRTLPSMVHRVSGQPQSVTASSDKAFEDWLND 170
Query: 187 NEGGQE--QGPSVEGL-NVPTKATLE-------VSSI----------IKKKPNQAKKGLG 226
+ G + QG G N P E +SS+ + + AK+G
Sbjct: 171 DLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEG-A 229
Query: 227 AKKGSLGAQK-------------LANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVS 273
K GS +QK L ++ + K AQ +K+KE K+ S VS
Sbjct: 230 TKFGSQASQKFWGHKQQPEPASELGHSLNENVLKPAQ--EKVKE----GKIFDDVSSGVS 283
Query: 274 SLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPI 333
+LA K + + +D SGK D G S + H S++ E+
Sbjct: 284 --QLASKGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFG 341
Query: 334 MAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSS-SFSSWDDSS 375
A+P K S DS+ + +S E RSS S+ W +S
Sbjct: 342 SAEPTKTRKSPSSDSWTCADTS-----TERRSSDSWEVWGSAS 379
>gi|23943872 small ArfGAP2 [Homo sapiens]
Length = 429
Score = 81.3 bits (199), Expect = 2e-15
Identities = 51/147 (34%), Positives = 71/147 (48%), Gaps = 20/147 (13%)
Query: 22 NKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQV 81
NK C DC +K P WAS GVF+CI C+G HR+LGVH+S ++S LD W+ Q++CMQ
Sbjct: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLD-QWTQEQIQCMQE 83
Query: 82 GGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKI-------KSLASQATRKHGTDLW- 133
GN A+ + + T + + R+K +SL A RK D W
Sbjct: 84 MGNGKANRLYEAYLPET-FRRPQIDPAVEGFIRDKYEKKKYMDRSLDINAFRKEKDDKWK 142
Query: 134 ----------LDSCVVPPLSPPPKEED 150
L+ V + P K+ED
Sbjct: 143 RGSEPVPEKKLEPVVFEKVKMPQKKED 169
>gi|113204622 stromal membrane-associated GTPase-activating
protein 1 isoform A [Homo sapiens]
Length = 467
Score = 80.1 bits (196), Expect = 4e-15
Identities = 41/83 (49%), Positives = 53/83 (63%), Gaps = 2/83 (2%)
Query: 5 SKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRS 64
++Q L + K LR NK C DC AK P WAS GVF+CI C+G HR+LGVH+S ++S
Sbjct: 14 NEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72
Query: 65 TELDSNWSWFQLRCMQVGGNASA 87
LD W+ Q++CMQ GN A
Sbjct: 73 VNLD-QWTAEQIQCMQDMGNTKA 94
>gi|21264558 stromal membrane-associated GTPase-activating protein
1 isoform B [Homo sapiens]
Length = 440
Score = 80.1 bits (196), Expect = 4e-15
Identities = 41/83 (49%), Positives = 53/83 (63%), Gaps = 2/83 (2%)
Query: 5 SKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRS 64
++Q L + K LR NK C DC AK P WAS GVF+CI C+G HR+LGVH+S ++S
Sbjct: 14 NEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72
Query: 65 TELDSNWSWFQLRCMQVGGNASA 87
LD W+ Q++CMQ GN A
Sbjct: 73 VNLD-QWTAEQIQCMQDMGNTKA 94
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 79.0 bits (193), Expect = 1e-14
Identities = 39/81 (48%), Positives = 52/81 (64%), Gaps = 1/81 (1%)
Query: 11 TIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSN 70
++ +R++SV N C DCG +P WASI GV LCI+CSG HRSLGVH S +RS LDS
Sbjct: 404 SVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDS- 462
Query: 71 WSWFQLRCMQVGGNASASSFF 91
W L+ M GN++ + +
Sbjct: 463 WEPELLKLMCELGNSAVNQIY 483
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 77.8 bits (190), Expect = 2e-14
Identities = 66/255 (25%), Positives = 117/255 (45%), Gaps = 22/255 (8%)
Query: 2 GDPSKQDIL---TIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVH 58
G+ SK+ +L + +R++ +P N C DCG +P WASI G+ LCI+CSG HRSLGVH
Sbjct: 388 GNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVH 447
Query: 59 LSFIRSTELDSNWSWFQLRCMQVGGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKIK 118
S +RS LD+ W L+ M GN + + + + R +EK
Sbjct: 448 FSKVRSLTLDT-WEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQR-----QEKEA 501
Query: 119 SLASQATRKHGTDLWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSR 178
+ ++ + D + S LSPP +++ F VS + + + P
Sbjct: 502 YIRAKYVERKFVDKYSIS-----LSPPEQQKKF----VSKSSEEKRLSISKFGPGDQVRA 552
Query: 179 PVETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKG--LGAKKGSLGAQK 236
++++ +N+ G +Q ++P +T+ +S+ + + + L +K + G Q
Sbjct: 553 SAQSSVRSNDSGIQQSSDDGRESLP--STVSANSLYEPEGERQDSSMFLDSKHLNPGLQL 610
Query: 237 LANTCFNEIEKQAQA 251
+ + K A+A
Sbjct: 611 YRASYEKNLPKMAEA 625
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 76.3 bits (186), Expect = 6e-14
Identities = 38/83 (45%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
Query: 7 QDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTE 66
Q+ + +R+V N C DC A NP WAS+ G +CI+CSG HR LG HLS +RS +
Sbjct: 659 QNAALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLD 718
Query: 67 LDSNWSWFQLRCMQVGGNASASS 89
LD +W L M GNA A+S
Sbjct: 719 LD-DWPPELLAVMTAMGNALANS 740
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 73.9 bits (180), Expect = 3e-13
Identities = 29/53 (54%), Positives = 39/53 (73%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELD 68
+R+ N +C DCGA NP+WAS+ G +CI+CSG HR+LG HLS +RS +LD
Sbjct: 937 IRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLD 989
>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
Length = 836
Score = 73.9 bits (180), Expect = 3e-13
Identities = 29/53 (54%), Positives = 39/53 (73%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELD 68
+R+ N +C DCGA NP+WAS+ G +CI+CSG HR+LG HLS +RS +LD
Sbjct: 581 IRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLD 633
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 72.8 bits (177), Expect = 7e-13
Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 1/85 (1%)
Query: 2 GDPSKQDIL-TIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60
G+ S +D+ I + ++ +P N +C DCG+ P+W S G+ CI+CSG HR +GVH+S
Sbjct: 430 GENSLEDLTKAIIEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHIS 489
Query: 61 FIRSTELDSNWSWFQLRCMQVGGNA 85
I+S ELD + L VG N+
Sbjct: 490 RIQSLELDKLGTSELLLAKNVGNNS 514
>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
Length = 804
Score = 72.8 bits (177), Expect = 7e-13
Identities = 33/78 (42%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
+R++ N C DC +NP+WAS+ G +CI+CSG HR+LG HLS +RS +LD +W
Sbjct: 562 IRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLD-DWPVEL 620
Query: 76 LRCMQVGGNASASSFFHQ 93
++ M GN A+S + +
Sbjct: 621 IKVMSSIGNELANSVWEE 638
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 72.8 bits (177), Expect = 7e-13
Identities = 33/78 (42%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
+R++ N C DC +NP+WAS+ G +CI+CSG HR+LG HLS +RS +LD +W
Sbjct: 615 IRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLD-DWPVEL 673
Query: 76 LRCMQVGGNASASSFFHQ 93
++ M GN A+S + +
Sbjct: 674 IKVMSSIGNELANSVWEE 691
>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
protein 11 [Homo sapiens]
Length = 550
Score = 70.1 bits (170), Expect = 5e-12
Identities = 38/92 (41%), Positives = 51/92 (55%), Gaps = 3/92 (3%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
++++ N C DC +NP WAS+ GV +CI+CSG HRSLG LS +RS ELD +W
Sbjct: 334 IQNMRGNSHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVEL 392
Query: 76 LRCMQVGGNASASSFFHQHGCSTNDTNAKYNS 107
+ M GN A+S + G S T S
Sbjct: 393 RKVMSSIGNDLANSIW--EGSSQGQTKPSIES 422
>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 4 [Homo sapiens]
Length = 663
Score = 69.3 bits (168), Expect = 8e-12
Identities = 38/92 (41%), Positives = 51/92 (55%), Gaps = 3/92 (3%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
++++ N C DC +NP WAS+ GV +CI+CSG HRSLG LS +RS ELD +W
Sbjct: 447 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVEL 505
Query: 76 LRCMQVGGNASASSFFHQHGCSTNDTNAKYNS 107
+ M GN A+S + G S T S
Sbjct: 506 RKVMSSIGNDLANSIW--EGSSQGQTKPSEKS 535
>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
Length = 663
Score = 68.9 bits (167), Expect = 1e-11
Identities = 34/76 (44%), Positives = 47/76 (61%), Gaps = 1/76 (1%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
++++ N C DC +NP WAS+ GV +CI+CSG HRSLG LS +RS ELD +W
Sbjct: 447 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVEL 505
Query: 76 LRCMQVGGNASASSFF 91
+ M GN A+S +
Sbjct: 506 RKVMSSIGNDLANSIW 521
>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 9 [Homo sapiens]
Length = 684
Score = 68.6 bits (166), Expect = 1e-11
Identities = 37/92 (40%), Positives = 50/92 (54%), Gaps = 3/92 (3%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
++++ N C DC +NP WAS+ GV +CI+CSG HRS G LS +RS ELD +W
Sbjct: 470 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD-DWPVEL 528
Query: 76 LRCMQVGGNASASSFFHQHGCSTNDTNAKYNS 107
+ M GN A+S + G S T S
Sbjct: 529 RKVMSSIGNELANSIW--EGSSQGQTKPSIKS 558
>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 10 [Homo sapiens]
Length = 684
Score = 68.6 bits (166), Expect = 1e-11
Identities = 37/92 (40%), Positives = 50/92 (54%), Gaps = 3/92 (3%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
++++ N C DC +NP WAS+ GV +CI+CSG HRS G LS +RS ELD +W
Sbjct: 470 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD-DWPVEL 528
Query: 76 LRCMQVGGNASASSFFHQHGCSTNDTNAKYNS 107
+ M GN A+S + G S T S
Sbjct: 529 RKVMSSIGNELANSIW--EGSSQGQTKPSIKS 558
>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
Length = 686
Score = 68.6 bits (166), Expect = 1e-11
Identities = 29/53 (54%), Positives = 38/53 (71%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELD 68
++++ N C DC +NP WAS+ GV +CI+CSG HRSLG HLS +RS ELD
Sbjct: 470 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVRSLELD 522
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 67.8 bits (164), Expect = 2e-11
Identities = 36/80 (45%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Query: 12 IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNW 71
+ +++SV N C DC P WASI GV LCI CSG HRSLGVH S +RS LDS W
Sbjct: 407 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDS-W 465
Query: 72 SWFQLRCMQVGGNASASSFF 91
++ M GN + +
Sbjct: 466 EPELVKLMCELGNVIINQIY 485
>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 8 [Homo sapiens]
Length = 663
Score = 67.4 bits (163), Expect = 3e-11
Identities = 37/92 (40%), Positives = 50/92 (54%), Gaps = 3/92 (3%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
++++ N C DC +NP WAS+ GV +CI+CSG H SLG LS +RS ELD +W
Sbjct: 447 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHHSLGTRLSRVRSLELD-DWPVEL 505
Query: 76 LRCMQVGGNASASSFFHQHGCSTNDTNAKYNS 107
+ M GN A+S + G S T S
Sbjct: 506 RKVMSSIGNDLANSIW--EGSSQGQTKPSEKS 535
>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 5 [Homo sapiens]
Length = 686
Score = 65.5 bits (158), Expect = 1e-10
Identities = 37/92 (40%), Positives = 50/92 (54%), Gaps = 3/92 (3%)
Query: 16 LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
++++ N C D +NP WAS+ GV +CI+CSG HRSLG LS +RS ELD +W
Sbjct: 470 IQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVEL 528
Query: 76 LRCMQVGGNASASSFFHQHGCSTNDTNAKYNS 107
+ M GN A+S + G S T S
Sbjct: 529 RKVMSSIGNDLANSIW--EGSSQGQTKPSVKS 558
>gi|6806913 centaurin, alpha 1 [Homo sapiens]
Length = 374
Score = 64.7 bits (156), Expect = 2e-10
Identities = 35/91 (38%), Positives = 52/91 (57%), Gaps = 6/91 (6%)
Query: 1 MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60
M ++ +L + +R P N C DCGA +P WAS T GVF+C+ CSG HR++ +S
Sbjct: 1 MAKERRRAVLELLQR----PGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVS 55
Query: 61 FIRSTELDSNWSWFQLRCMQVGGNASASSFF 91
++S LD+ W Q+ M GN +A + F
Sbjct: 56 KVKSVRLDA-WEEAQVEFMASHGNDAARARF 85
>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform b [Homo sapiens]
Length = 961
Score = 63.5 bits (153), Expect = 4e-10
Identities = 27/57 (47%), Positives = 36/57 (63%)
Query: 12 IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELD 68
I ++ + N VC DCGA +P+W S G+ CI+CSG HR LGVH S ++S LD
Sbjct: 423 IISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLD 479
>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform a [Homo sapiens]
Length = 1006
Score = 63.5 bits (153), Expect = 4e-10
Identities = 27/57 (47%), Positives = 36/57 (63%)
Query: 12 IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELD 68
I ++ + N VC DCGA +P+W S G+ CI+CSG HR LGVH S ++S LD
Sbjct: 423 IISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLD 479
>gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
3 [Homo sapiens]
Length = 1544
Score = 62.0 bits (149), Expect = 1e-09
Identities = 29/81 (35%), Positives = 50/81 (61%), Gaps = 1/81 (1%)
Query: 12 IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSN- 70
+ +++ S N+ C DCG+ P WA++ GV +C C+G HR+LG +S ++S +LD++
Sbjct: 491 VAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSV 550
Query: 71 WSWFQLRCMQVGGNASASSFF 91
WS ++ V GN A+ F+
Sbjct: 551 WSNEIVQLFIVLGNDRANRFW 571
>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform b [Homo sapiens]
Length = 894
Score = 61.2 bits (147), Expect = 2e-09
Identities = 27/57 (47%), Positives = 34/57 (59%)
Query: 12 IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELD 68
+ ++S P N C DCGA +P+W S GV CI CSG HR LGV S ++S LD
Sbjct: 419 LIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLD 475
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,785,830
Number of Sequences: 37866
Number of extensions: 896224
Number of successful extensions: 3314
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 83
Number of HSP's that attempted gapping in prelim test: 3047
Number of HSP's gapped (non-prelim): 288
length of query: 516
length of database: 18,247,518
effective HSP length: 107
effective length of query: 409
effective length of database: 14,195,856
effective search space: 5806105104
effective search space used: 5806105104
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.