Search of human proteins with 113722116

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|113722116 plexin A2 [Homo sapiens]
         (1894 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|113722116 plexin A2 [Homo sapiens]                                3841   0.0  
gi|157738645 plexin A4 isoform 1 [Homo sapiens]                      2613   0.0  
gi|49355818 plexin A1 [Homo sapiens]                                 2452   0.0  
gi|59710104 plexin A3 [Homo sapiens]                                 2268   0.0  
gi|253795481 plexin B3 isoform 2 [Homo sapiens]                       966   0.0  
gi|29336063 plexin B3 isoform 1 [Homo sapiens]                        963   0.0  
gi|149363636 plexin B2 [Homo sapiens]                                 924   0.0  
gi|157694524 plexin D1 [Homo sapiens]                                 889   0.0  
gi|194272180 plexin B1 [Homo sapiens]                                 788   0.0  
gi|40254442 plexin B1 [Homo sapiens]                                  788   0.0  
gi|157738643 plexin A4 isoform 2 [Homo sapiens]                       527   e-149
gi|157738647 plexin A4 isoform 3 [Homo sapiens]                       520   e-147
gi|5032223 plexin C1 [Homo sapiens]                                   422   e-117
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]     149   3e-35
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]    149   3e-35
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s...   122   3e-27
gi|39777610 semaphorin 4B precursor [Homo sapiens]                     72   4e-12
gi|39777608 semaphorin 4B precursor [Homo sapiens]                     72   4e-12
gi|126116589 fibrocystin L [Homo sapiens]                              70   3e-11
gi|21361914 semaphorin B [Homo sapiens]                                59   6e-08
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]                     58   8e-08
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]           56   3e-07
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]           56   3e-07
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]           56   3e-07
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]           56   3e-07
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]           56   3e-07
gi|147904700 semaphorin 5A [Homo sapiens]                              55   5e-07
gi|188497703 semaphorin 3F [Homo sapiens]                              55   6e-07
gi|9910362 semaphorin sem2 [Homo sapiens]                              55   6e-07
gi|157388902 semaphorin 4C [Homo sapiens]                              55   6e-07

>gi|113722116 plexin A2 [Homo sapiens]
          Length = 1894

 Score = 3841 bits (9962), Expect = 0.0
 Identities = 1894/1894 (100%), Positives = 1894/1894 (100%)

Query: 1    MEQRRPWPRALEVDSRSVVLLSVVWVLLAPPAAGMPQFSTFHSENRDWTFNHLTVHQGTG 60
            MEQRRPWPRALEVDSRSVVLLSVVWVLLAPPAAGMPQFSTFHSENRDWTFNHLTVHQGTG
Sbjct: 1    MEQRRPWPRALEVDSRSVVLLSVVWVLLAPPAAGMPQFSTFHSENRDWTFNHLTVHQGTG 60

Query: 61   AVYVGAINRVYKLTGNLTIQVAHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIID 120
            AVYVGAINRVYKLTGNLTIQVAHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIID
Sbjct: 61   AVYVGAINRVYKLTGNLTIQVAHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIID 120

Query: 121  YSENRLLACGSLYQGVCKLLRLDDLFILVEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDG 180
            YSENRLLACGSLYQGVCKLLRLDDLFILVEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDG
Sbjct: 121  YSENRLLACGSLYQGVCKLLRLDDLFILVEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDG 180

Query: 181  KLFIGTAVDGKQDYFPTLSSRKLPRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFD 240
            KLFIGTAVDGKQDYFPTLSSRKLPRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFD
Sbjct: 181  KLFIGTAVDGKQDYFPTLSSRKLPRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFD 240

Query: 241  IFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGC 300
            IFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGC
Sbjct: 241  IFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGC 300

Query: 301  TRAGVEYRLLQAAYLAKPGDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPI 360
            TRAGVEYRLLQAAYLAKPGDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPI
Sbjct: 301  TRAGVEYRLLQAAYLAKPGDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPI 360

Query: 361  RAINLQIKERLQSCYQGEGNLELNWLLGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVE 420
            RAINLQIKERLQSCYQGEGNLELNWLLGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVE
Sbjct: 361  RAINLQIKERLQSCYQGEGNLELNWLLGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVE 420

Query: 421  GLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGS 480
            GLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGS
Sbjct: 421  GLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGS 480

Query: 481  PILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRR 540
            PILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRR
Sbjct: 481  PILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRR 540

Query: 541  DKCQQAWEPNRFAASISQCVSLAVHPSSISVSEHSRLLSLVVSDAPDLSAGIACAFGNLT 600
            DKCQQAWEPNRFAASISQCVSLAVHPSSISVSEHSRLLSLVVSDAPDLSAGIACAFGNLT
Sbjct: 541  DKCQQAWEPNRFAASISQCVSLAVHPSSISVSEHSRLLSLVVSDAPDLSAGIACAFGNLT 600

Query: 601  EVEGQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKFYNCSAHQ 660
            EVEGQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKFYNCSAHQ
Sbjct: 601  EVEGQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKFYNCSAHQ 660

Query: 661  LCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLVPTEEILIPVGEVKPI 720
            LCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLVPTEEILIPVGEVKPI
Sbjct: 661  LCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLVPTEEILIPVGEVKPI 720

Query: 721  TLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQNSSYQYDGMDISNLAVD 780
            TLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQNSSYQYDGMDISNLAVD
Sbjct: 721  TLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQNSSYQYDGMDISNLAVD 780

Query: 781  FAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTS 840
            FAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTS
Sbjct: 781  FAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTS 840

Query: 841  PSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVP 900
            PSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVP
Sbjct: 841  PSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVP 900

Query: 901  CTPLPGEYIIAEQIVCEMGHALVGTTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLN 960
            CTPLPGEYIIAEQIVCEMGHALVGTTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLN
Sbjct: 901  CTPLPGEYIIAEQIVCEMGHALVGTTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLN 960

Query: 961  PIRGPESGGTMVTITGHYLGAGSSVAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPV 1020
            PIRGPESGGTMVTITGHYLGAGSSVAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPV
Sbjct: 961  PIRGPESGGTMVTITGHYLGAGSSVAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPV 1020

Query: 1021 SVSVDRAHVDSNLQFEYIDDPRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNG 1080
            SVSVDRAHVDSNLQFEYIDDPRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNG
Sbjct: 1021 SVSVDRAHVDSNLQFEYIDDPRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNG 1080

Query: 1081 KESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQSLLIYNDTKFIYY 1140
            KESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQSLLIYNDTKFIYY
Sbjct: 1081 KESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQSLLIYNDTKFIYY 1140

Query: 1141 PNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGETPCAVTVSETQLL 1200
            PNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGETPCAVTVSETQLL
Sbjct: 1141 PNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGETPCAVTVSETQLL 1200

Query: 1201 CEPPNLTGQHKVMVHVGGMVFSPGSVSVISDSLLTLPAIVSIAAGGSLLLIIVIIVLIAY 1260
            CEPPNLTGQHKVMVHVGGMVFSPGSVSVISDSLLTLPAIVSIAAGGSLLLIIVIIVLIAY
Sbjct: 1201 CEPPNLTGQHKVMVHVGGMVFSPGSVSVISDSLLTLPAIVSIAAGGSLLLIIVIIVLIAY 1260

Query: 1261 KRKSRENDLTLKRLQMQMDNLESRVALECKEAFAELQTDINELTSDLDRSGIPYLDYRTY 1320
            KRKSRENDLTLKRLQMQMDNLESRVALECKEAFAELQTDINELTSDLDRSGIPYLDYRTY
Sbjct: 1261 KRKSRENDLTLKRLQMQMDNLESRVALECKEAFAELQTDINELTSDLDRSGIPYLDYRTY 1320

Query: 1321 AMRVLFPGIEDHPVLRELEVQGNGQQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSM 1380
            AMRVLFPGIEDHPVLRELEVQGNGQQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSM
Sbjct: 1321 AMRVLFPGIEDHPVLRELEVQGNGQQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSM 1380

Query: 1381 RDRGNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTN 1440
            RDRGNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTN
Sbjct: 1381 RDRGNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTN 1440

Query: 1441 WFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTL 1500
            WFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTL
Sbjct: 1441 WFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTL 1500

Query: 1501 ILNCVNPDNENSPEIPVKVLNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRI 1560
            ILNCVNPDNENSPEIPVKVLNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRI
Sbjct: 1501 ILNCVNPDNENSPEIPVKVLNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRI 1560

Query: 1561 ARVVLQDEDITTKIEGDWKRLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISR 1620
            ARVVLQDEDITTKIEGDWKRLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISR
Sbjct: 1561 ARVVLQDEDITTKIEGDWKRLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISR 1620

Query: 1621 YDSSFRYTGSPDSLRSRAPMITPDLESGVKVWHLVKNHDHGDQKEGDRGSKMVSEIYLTR 1680
            YDSSFRYTGSPDSLRSRAPMITPDLESGVKVWHLVKNHDHGDQKEGDRGSKMVSEIYLTR
Sbjct: 1621 YDSSFRYTGSPDSLRSRAPMITPDLESGVKVWHLVKNHDHGDQKEGDRGSKMVSEIYLTR 1680

Query: 1681 LLATKGTLQKFVDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKS 1740
            LLATKGTLQKFVDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKS
Sbjct: 1681 LLATKGTLQKFVDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKS 1740

Query: 1741 NCLPLRFWVNVIKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLY 1800
            NCLPLRFWVNVIKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLY
Sbjct: 1741 NCLPLRFWVNVIKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLY 1800

Query: 1801 AKDIPSYKSWVERYYADIAKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKY 1860
            AKDIPSYKSWVERYYADIAKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKY
Sbjct: 1801 AKDIPSYKSWVERYYADIAKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKY 1860

Query: 1861 SEELIGALEQDEQARRQRLAYKVEQLINAMSIES 1894
            SEELIGALEQDEQARRQRLAYKVEQLINAMSIES
Sbjct: 1861 SEELIGALEQDEQARRQRLAYKVEQLINAMSIES 1894


>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
          Length = 1894

 Score = 2613 bits (6773), Expect = 0.0
 Identities = 1271/1870 (67%), Positives = 1509/1870 (80%), Gaps = 10/1870 (0%)

Query: 29   APPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQVAHKTGPE 88
            AP +     F TF  E  +  FNHL V + TG +Y+GA+NR+YKL+ +L + V H+TGP+
Sbjct: 31   APLSQKQRSFVTFRGEPAEG-FNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPD 89

Query: 89   EDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLFIL 148
            EDN  CYPP IVQ C+E LT TNNVNK+L+IDY ENRL+ACGSLYQG+CKLLRL+DLF L
Sbjct: 90   EDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKL 149

Query: 149  VEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKLPRDPE 208
             EP HKKEHYLS VN++G+++GVIV     D KLFI TAVDGK +YFPT+SSRKL ++ E
Sbjct: 150  GEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSE 209

Query: 209  SSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPE--TPEGV 266
            +  M  Y  H +FV+S+IKIPSDT  ++  FDI+Y+YGF+SG FVYFLT+QPE  +P G 
Sbjct: 210  ADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPG- 268

Query: 267  AINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPGDSLAQAF 326
              ++  +  YTS++VRLCK+D  F+SYV +P GC R+GVEYRLLQAAYL+K G  L +  
Sbjct: 269  --STTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTL 326

Query: 327  NITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWL 386
             +   DD+LF +FSKGQK+     D+SALC F ++ IN +IKERLQSCY+GEG L+L WL
Sbjct: 327  GVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWL 386

Query: 387  LGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSVASYVYNGYSVV 446
              KD+ C+ A + IDDNFCGLD+N PLG S  V G+ ++T  RDRMTSV +YVY  +S+ 
Sbjct: 387  KVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLA 446

Query: 447  FVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQRYLYVMSERQVTRV 506
            FVGTKSGKLKKIR DGP    +QYE V V+  G P+LRDMAFS D   LY+MSERQ+TRV
Sbjct: 447  FVGTKSGKLKKIRVDGPRGNALQYETVQVVDPG-PVLRDMAFSKDHEQLYIMSERQLTRV 505

Query: 507  PVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEPNRFAASISQCVSLAVHP 566
            PVESC QY +CGECL SGDPHCGWC LHN C+R+++C+++ EP RFA+ + QCV L VHP
Sbjct: 506  PVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHP 565

Query: 567  SSISVSEHSRLLSLVVSDAPDLSAGIACAFGNLTEVEGQVSGSQVICISPGPKDVP-VIP 625
            ++ISVS+++ LL L   + P+LSAG+ C F +L+E++G V G+Q+ C SP  K+VP +I 
Sbjct: 566  NNISVSQYNVLLVLETYNVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIIT 625

Query: 626  LDQDWFGLELQLRSKETGKIFVSTEFKFYNCSAHQLCLSCVNSAFRCHWCKYRNLCTHDP 685
             + D   ++LQL+SKETG  F ST F FYNCS H  CLSCV S +RCHWCKYR++CTHDP
Sbjct: 626  ENGDHHVVQLQLKSKETGMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDP 685

Query: 686  TTCSFQEGRINISEDCPQLVPTEEILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQG 745
             TCSFQEGR+ + EDCPQL+  ++IL+PV  +KPITLKA+NLPQPQSGQRGYEC+LNIQG
Sbjct: 686  KTCSFQEGRVKLPEDCPQLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQG 745

Query: 746  AIHRVPALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCA 805
            +  RVPALRFNSSSVQCQN+SY Y+GM+I+NL V+  VVWNG+F IDNP   KVHLYKC 
Sbjct: 746  SEQRVPALRFNSSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCG 805

Query: 806  AQRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILT 865
            A RESCGLCLKAD  F CGWC G  +CTL QHC +  S WL+ S    KC+NP+ITEI+ 
Sbjct: 806  AMRESCGLCLKADPDFACGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIP 865

Query: 866  VSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVGT 925
            V+GP EGGT+VTI G NLGL+F +IA HV+VAGV C+PL   YI AEQIVCEMG A    
Sbjct: 866  VTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQ 925

Query: 926  TSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSV 985
             +G V +C+  C+PEFM +S Q Y F+  ++  L P RGP SGGT VTITG  L AGS+V
Sbjct: 926  HAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNV 985

Query: 986  AVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPVSVSVDRAHVDSNLQFEYIDDPRVQR 1045
             V  G Q C F+ RS S IVC +  SS+ +  + VSV VDRA +  +L F+Y++DP + R
Sbjct: 986  VVMFGKQPCLFHRRSPSYIVC-NTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVR 1044

Query: 1046 IEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNGKESVNVCKVVNTTTLTCLAPSLTTD 1105
            IEPEWSI SG+TP+ + G +LD+IQ P+IR K  GKE +N+C+V+N T +TC AP+L   
Sbjct: 1045 IEPEWSIVSGNTPIAVWGTHLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALG 1104

Query: 1106 YRPGLDTVERPDEFGFVFNNVQSLLIYNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILK 1165
                 D  ERP+EFGF+ +NVQSLLI N T F YYPNP FE   P+G+L+ KPG+PIILK
Sbjct: 1105 PDHQSDLTERPEEFGFILDNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILK 1164

Query: 1166 GKNLCPPASGG-AKLNYTVLIGETPCAVTVSETQLLCEPPNLTGQHKVMVHVGGMVFSPG 1224
            GKNL PP +GG  KLNYTVL+GE PC VTVS+ QLLCE PNL G+HKVM  VGGM +SPG
Sbjct: 1165 GKNLIPPVAGGNVKLNYTVLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPG 1224

Query: 1225 SVSVISDSLLTLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESR 1284
             V +  DS L+LPAIVSIA  G LL+I ++ VLIAYKRKSRE+DLTLKRLQMQMDNLESR
Sbjct: 1225 MVYIAPDSPLSLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESR 1284

Query: 1285 VALECKEAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNG 1344
            VALECKEAFAELQTDI+ELTSDLD +GIP+LDYRTY MRVLFPGIEDHPVLR+LEV G  
Sbjct: 1285 VALECKEAFAELQTDIHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYR 1344

Query: 1345 QQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDV 1404
            Q+ VEK LKLFAQLINNKVFLL+FIRTLE QRSFSMRDRGNVASLIMT LQ +LEYATDV
Sbjct: 1345 QERVEKGLKLFAQLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDV 1404

Query: 1405 LKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCA 1464
            LKQLL+DLIDKNLE+KNHPKLLLRRTESVAEKMLTNWF FLL+KFLKECAGEPLF L+CA
Sbjct: 1405 LKQLLADLIDKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCA 1464

Query: 1465 IKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLILNCVNPDNENSPEIPVKVLNCDT 1524
            IKQQMEKGPIDAITGEARYSLSEDKLIRQQI+YKTL+L+CV+PDN NSPE+PVK+LNCDT
Sbjct: 1465 IKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDT 1524

Query: 1525 ITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTL 1584
            ITQVKEKILDA++KNVP S RP+A DMDLEWRQG  AR++LQDEDITTKIE DWKRLNTL
Sbjct: 1525 ITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTL 1584

Query: 1585 MHYQVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPD 1644
             HYQV D SVVALV KQ ++YN   ++++SRTS S+Y++  RYTGSPDSLRSR PMITPD
Sbjct: 1585 AHYQVPDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPD 1644

Query: 1645 LESGVKVWHLVKNHDHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETLFSTVH 1704
            LESGVK+WHLVKNH+HGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFET+FST H
Sbjct: 1645 LESGVKMWHLVKNHEHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAH 1704

Query: 1705 RGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKG 1764
            RGSALPLAIKYMFDFLDEQAD+H IHD  VRHTWKSNCLPLRFWVN+IKNPQFVFDIHK 
Sbjct: 1705 RGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKN 1764

Query: 1765 SITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADIAKLPAI 1824
            SITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYK+WVERYY+DI K+PAI
Sbjct: 1765 SITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAI 1824

Query: 1825 SDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQRLAYKVE 1884
            SDQDMNAYLAEQSR+H  EFN +SAL+EI+SYV KYSEE++G L+ D+Q  +Q+LAYK+E
Sbjct: 1825 SDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLE 1884

Query: 1885 QLINAMSIES 1894
            Q+I  MS++S
Sbjct: 1885 QVITLMSLDS 1894


>gi|49355818 plexin A1 [Homo sapiens]
          Length = 1873

 Score = 2452 bits (6354), Expect = 0.0
 Identities = 1204/1883 (63%), Positives = 1468/1883 (77%), Gaps = 22/1883 (1%)

Query: 24   VWVLLAPPAAG---MPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQ 80
            +W     P AG    P F TF +   DW   HL VH+ TG VYVGA+NR+YKL+GNLT+ 
Sbjct: 1    MWAEAGLPRAGGGSQPPFRTFSAS--DWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLL 58

Query: 81   VAHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLL 140
             AH TGP EDN+ CYPP  VQ C   L  T+NVNKLL++DY+ NRLLACGS  QG+C+ L
Sbjct: 59   RAHVTGPVEDNEKCYPPPSVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFL 118

Query: 141  RLDDLFILVEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDG--KLFIGTAVDGKQDYFPTL 198
            RLDDLF L EP H+KEHYLSSV + G+M GV++      G  KLF+GT +DGK +YFPTL
Sbjct: 119  RLDDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTL 178

Query: 199  SSRKLPRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTV 258
            SSR+L  + E + M  +    +FVSS +KIPSDTL+    FDI+Y+Y F S  FVY+LT+
Sbjct: 179  SSRRLMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTL 238

Query: 259  QPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKP 318
            Q +T +  + ++AG+ F+TS+IVRLC DDPKF+SYV  P GC +AGVEYRL+Q AYL++P
Sbjct: 239  QLDT-QLTSPDAAGEHFFTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRP 297

Query: 319  GDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGE 378
            G +LA    +   +DVLF +F++GQK    PP +SALC F +RAI  +IKER+QSCY+GE
Sbjct: 298  GRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGE 357

Query: 379  GNLELNWLLGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSVASY 438
            G L L WLL K++ C  +P+ IDD+FCG D NQPLGG+  +EG  L+    D +T+VA+Y
Sbjct: 358  GKLSLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAY 417

Query: 439  VYNGYSVVFVGTKSGKLKKIRADGPPHGG---VQYEMVSVLKDGSPILRDMAFSIDQRYL 495
             Y G +VVF GT+SG+++KI  D    GG   + YE V V ++GSPILRD+  S + +YL
Sbjct: 418  DYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESV-VAQEGSPILRDLVLSPNHQYL 476

Query: 496  YVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEPNRFAAS 555
            Y M+E+QVTRVPVESC QYT+C  CL S DPHCGWC LH++CSRRD C++A EP RFAA 
Sbjct: 477  YAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAAD 536

Query: 556  ISQCVSLAVHPSSISVSEHSRLLSLVVSDAPDLSAGIACAFGNLTEVEGQVSGSQVICIS 615
            + QCV L V P ++SV+     L L   + PDLSAG+ C+F + TE E  +   ++ C S
Sbjct: 537  LLQCVQLTVQPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHCRS 596

Query: 616  PGPKDVPVIPLDQ-DWFGLELQLRSKETGKIFVSTEFKFYNCSAHQLCLSCVNSAFRCHW 674
            P  ++V  I   Q D   ++L L+SKETGK F S +F FYNCS HQ CLSCVN +F CHW
Sbjct: 597  PSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQSCLSCVNGSFPCHW 656

Query: 675  CKYRNLCTHDPTTCSFQEGRINISEDCPQLVPTEEILIPVGEVKPITLKARNLPQPQSGQ 734
            CKYR++CTH+   C+F EGR+N+SEDCPQ++P+ +I +PVG VKPITL ARNLPQPQSGQ
Sbjct: 657  CKYRHVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPVGVVKPITLAARNLPQPQSGQ 716

Query: 735  RGYECVLNIQGAIHRVPALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNP 794
            RGYEC+ +I G+  RV ALRFNSSS+QCQNSSY Y+G D+S+L V+ +VVWNGNF+IDNP
Sbjct: 717  RGYECLFHIPGSPARVTALRFNSSSLQCQNSSYSYEGNDVSDLPVNLSVVWNGNFVIDNP 776

Query: 795  QDLKVHLYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPS-SPWLDWSSHNV 853
            Q+++ HLYKC A RESCGLCLKAD +FECGWC  ERRC+L  HC + + + W+     + 
Sbjct: 777  QNIQAHLYKCPALRESCGLCLKADPRFECGWCVAERRCSLRHHCAADTPASWMHARHGSS 836

Query: 854  KCSNPQITEILTVSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQ 913
            +C++P+I ++   +GP +GGTR+TI G NLGL F ++   V+V  V C+P+  EYI AEQ
Sbjct: 837  RCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQ 896

Query: 914  IVCEMGHAL-VGTTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMV 972
            IVCE+G A  V      V +C+ +C P +   S +++TFV P+   ++P RGP SGGT +
Sbjct: 897  IVCEIGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWI 956

Query: 973  TITGHYLGAGSSVAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPVSVSVDRAHVDS- 1031
             I G +L AGS VAV +G + C F  R+  EI C++PP  +  G  P+ ++++RA + + 
Sbjct: 957  GIEGSHLNAGSDVAVSVGGRPCSFSWRNSREIRCLTPPGQSP-GSAPIIININRAQLTNP 1015

Query: 1032 NLQFEYIDDPRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNGKESVNVCKVVN 1091
             +++ Y +DP + RI+PEWSI SG T LT+TG NL  ++EPRIR K+ G E  N C V N
Sbjct: 1016 EVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRIRAKYGGIERENGCLVYN 1075

Query: 1092 TTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQSLLIYNDTKFIYYPNPTFELLSPT 1151
             TT+ C APS+    R   +  ERPDE GFV +NV+SLL+ N T F+YYP+P  E LSPT
Sbjct: 1076 DTTMVCRAPSVANPVRSPPELGERPDELGFVMDNVRSLLVLNSTSFLYYPDPVLEPLSPT 1135

Query: 1152 GVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGETPCAVTVSETQLLCEPPNLTGQHK 1211
            G+L+ KP SP+ILKG+NL PPA G ++LNYTVLIG TPC +TVSETQLLCE PNLTGQHK
Sbjct: 1136 GLLELKPSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTLTVSETQLLCEAPNLTGQHK 1195

Query: 1212 VMVHVGGMVFSPGSVSVISDSLLTLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTL 1271
            V V  GG  FSPG++ V SDSLLTLPAIV I  GG LLL++++ VLIAYKRKSR+ D TL
Sbjct: 1196 VTVRAGGFEFSPGTLQVYSDSLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRDADRTL 1255

Query: 1272 KRLQMQMDNLESRVALECKEAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIED 1331
            KRLQ+QMDNLESRVALECKEAFAELQTDI+ELT+DLD +GIP+LDYRTYAMRVLFPGIED
Sbjct: 1256 KRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLFPGIED 1315

Query: 1332 HPVLRELEVQGNGQQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIM 1391
            HPVL+E+EVQ N    VEK+L LF QL+  K FLLTFIRTLE QRSFSMRDRGNVASLIM
Sbjct: 1316 HPVLKEMEVQAN----VEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRGNVASLIM 1371

Query: 1392 TGLQGRLEYATDVLKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLK 1451
            T LQG +EYAT VLKQLLSDLI+KNLE+KNHPKLLLRRTESVAEKMLTNWF FLL+KFLK
Sbjct: 1372 TALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLK 1431

Query: 1452 ECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLILNCVNPDNEN 1511
            ECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQI+YKTL LNCVNP+NEN
Sbjct: 1432 ECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNCVNPENEN 1491

Query: 1512 SPEIPVKVLNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDIT 1571
            +PE+PVK L+CDT+TQ KEK+LDA YK VPYSQRP+A DMDLEWRQGR+AR++LQDED+T
Sbjct: 1492 APEVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQGRMARIILQDEDVT 1551

Query: 1572 TKIEGDWKRLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSP 1631
            TKI+ DWKRLNTL HYQV+D S VALVPKQTS+YNI  S++ ++ S+SRY+S  R   SP
Sbjct: 1552 TKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTK-SLSRYESMLRTASSP 1610

Query: 1632 DSLRSRAPMITPDLESGVKVWHLVKNHDHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKF 1691
            DSLRSR PMITPDLESG K+WHLVKNHDH DQ+EGDRGSKMVSEIYLTRLLATKGTLQKF
Sbjct: 1611 DSLRSRTPMITPDLESGTKLWHLVKNHDHLDQREGDRGSKMVSEIYLTRLLATKGTLQKF 1670

Query: 1692 VDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNV 1751
            VDDLFET+FST HRGSALPLAIKYMFDFLDEQAD+H IHD DVRHTWKSNCLPLRFWVNV
Sbjct: 1671 VDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHQIHDADVRHTWKSNCLPLRFWVNV 1730

Query: 1752 IKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWV 1811
            IKNPQFVFDIHK SITDACLSVVAQTFMDSCSTSEH+LGKDSPSNKLLYAKDIP+YKSWV
Sbjct: 1731 IKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWV 1790

Query: 1812 ERYYADIAKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQD 1871
            ERYYADIAK+PAISDQDM+AYLAEQSRLH  +FN +SAL+EIYSY++KY +E++ ALE+D
Sbjct: 1791 ERYYADIAKMPAISDQDMSAYLAEQSRLHLSQFNSMSALHEIYSYITKYKDEILAALEKD 1850

Query: 1872 EQARRQRLAYKVEQLINAMSIES 1894
            EQARRQRL  K+EQ+++ M++ S
Sbjct: 1851 EQARRQRLRSKLEQVVDTMALSS 1873


>gi|59710104 plexin A3 [Homo sapiens]
          Length = 1871

 Score = 2268 bits (5877), Expect = 0.0
 Identities = 1117/1852 (60%), Positives = 1402/1852 (75%), Gaps = 14/1852 (0%)

Query: 47   DWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQVAHKTGPEEDNKSCYPPLIVQPCSEV 106
            D T  HL VH+ TG V+VGA+NRV+KL  NLT   AH TGP EDN  CYPP  ++ C+  
Sbjct: 30   DTTLTHLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHR 89

Query: 107  LTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLFILVEPSHKKEHYLSSVNKTG 166
            L   +N+NKLL+IDY+  RL+ACGS++QG+C+ LRLDDLF L EP H+KEHYLS   +  
Sbjct: 90   LAPVDNINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSGAQEPD 149

Query: 167  TMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKLPRDPESSAMLDYELHSDFVSSLI 226
            +M GVIV       KLF+GTAVDGK +YFPTLSSRKL  D +S+ M       +FVSS I
Sbjct: 150  SMAGVIVEQGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQI 209

Query: 227  KIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKD 286
            KIPSDTL+L   FDI+YIYGF S  FVYFLT+Q +T + + +++AG+ F+TS+IVR+C  
Sbjct: 210  KIPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTL-LDTAGEKFFTSKIVRMCAG 268

Query: 287  DPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPGDSLAQAFNITSQDDVLFAIFSKGQKQY 346
            D +F+SYV  P GC+  GVEYRL+Q+A+LAKPG  LAQA  + + +DVLF IFS+GQK  
Sbjct: 269  DSEFYSYVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNR 328

Query: 347  HHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWLLGKDVQCTKAPVPIDDNFCG 406
              PP  + LC F +  IN  I+ R+QSCY+GEG L L WLL K++ C   P+ I+ NFCG
Sbjct: 329  ASPPRQTILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTPMQINGNFCG 388

Query: 407  LDINQPLGGSTPVEGLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHG 466
            L +NQPLGG   +EGL L   S D M SVA+Y Y  +SVVF+GT+SG LKK+R DG    
Sbjct: 389  LVLNQPLGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDA 448

Query: 467  GVQYEMVSVLKDGSPILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDP 526
             + YE V V+ DGSPILRD+ FS D R++Y++SE+QV+++PVE+CEQY +C  CL SGDP
Sbjct: 449  HL-YETVPVV-DGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDP 506

Query: 527  HCGWCALHNMCSRRDKCQQAWEPNRFAASISQCVSLAVHPSSISVSEHSRLLSLVVSDAP 586
            HCGWC L + C R   C  A  P+ FA  +S+CV + V P+++SV+     L++ + + P
Sbjct: 507  HCGWCVLRHRCCREGACLGASAPHGFAEELSKCVQVRVRPNNVSVTSPGVQLTVTLHNVP 566

Query: 587  DLSAGIACAFGNLTEVEGQVSGS-QVICISPGPKDVPVIPLDQDWFG-LELQLRSKETGK 644
            DLSAG++CAF    E E  +  S +++C SP  +++  +         + LQL SKETG 
Sbjct: 567  DLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGV 626

Query: 645  IFVSTEFKFYNCSAHQLCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQL 704
             F   +F FYNCS  Q C+SCV S + CHWCKYR+ CT  P  CSFQEGR++  E CP++
Sbjct: 627  RFAGADFVFYNCSVLQSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPEI 686

Query: 705  VPTEEILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQN 764
            +P+ ++LIPVG ++P+TL+A+NLPQPQSGQ+ YECV+ +QG   RVPA+RFNSSSVQCQN
Sbjct: 687  LPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAVRFNSSSVQCQN 746

Query: 765  SSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCLKADRKFECG 824
            +SY Y+G +  +  +DF+VVW+G+F ID P   +  LYKC AQR SCGLCLKAD +F CG
Sbjct: 747  ASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRFNCG 806

Query: 825  WCSGERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVNLG 884
            WC  E RC L  HC +P + W+  S    +CS+P+IT+I  + GP EGGTRVTI G NLG
Sbjct: 807  WCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVGDNLG 866

Query: 885  LDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVGTTS-GPVRLCIGECKPEFMT 943
            L   E+   ++VAGV C  +P EYI AE+IVCEM  +LV +   GPV LC+G+C  +F T
Sbjct: 867  LLSREVG--LRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSADFRT 924

Query: 944  KSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSVAVYLGNQTCEFYGRSMSE 1003
            +S Q Y+FV P+   ++P RGP SGGT +TI+G  L AGS V V + +  C+F  R    
Sbjct: 925  QSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQFVRRDAKA 984

Query: 1004 IVCVSPPSSNGLGPVPVSVSVDRAHVDS-NLQFEYIDDPRVQRIEPEWSIASGHTPLTIT 1062
            IVC+SP S+ G    P+++++DRA++ S  L + Y  DP V R+EP WSI +G T +T++
Sbjct: 985  IVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVS 1044

Query: 1063 GFNLDVIQEPRIRVKFNGKESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFV 1122
            G +L  +QEPR+R K+ G E+ N C+V+N T + C AP +           E PDEFGF+
Sbjct: 1045 GTHLLTVQEPRVRAKYRGIETTNTCQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFL 1104

Query: 1123 FNNVQSLLIYNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLNYT 1182
             ++VQ+    N + F YYP+P+FE L P+GVLD KPGS ++LKGKNL P A+G ++LNYT
Sbjct: 1105 LDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYT 1164

Query: 1183 VLIGETPCAVTVSETQLLCEPPNLTGQHKVMVHVGGMVFSPGSVSVISDSLLTLPAIVSI 1242
            VLIG  PC++TVS+TQLLC+ P+ TG+  VMV VGG+ F  G++ + ++  LTLPA++ +
Sbjct: 1165 VLIGGQPCSLTVSDTQLLCDSPSQTGRQPVMVLVGGLEFWLGTLHISAERALTLPAMMGL 1224

Query: 1243 AAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECKEAFAELQTDINE 1302
            AAGG LLL+ +  VL+AYKRK+++ D TLKRLQ+QMDNLESRVALECKEAFAELQTDINE
Sbjct: 1225 AAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINE 1284

Query: 1303 LTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQHVEKALKLFAQLINNK 1362
            LT+ +D   IP+LDYRTYA+RVLFPGIE HPVL+EL+   N    VEKAL+LF QL++++
Sbjct: 1285 LTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTPPN----VEKALRLFGQLLHSR 1340

Query: 1363 VFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLENKNH 1422
             F+LTFI TLE Q SFSMRDRG VASL M  LQ RL+YAT +LKQLL+DLI+KNLE+KNH
Sbjct: 1341 AFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESKNH 1400

Query: 1423 PKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEAR 1482
            PKLLLRRTESVAEKMLTNWF FLLHKFLKECAGEPLF+LYCAIKQQMEKGPIDAITGEAR
Sbjct: 1401 PKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGEAR 1460

Query: 1483 YSLSEDKLIRQQIEYKTLILNCVNPDNENSPEIPVKVLNCDTITQVKEKILDAVYKNVPY 1542
            YSLSEDKLIRQQI+YKTL L+CV P+NE S ++PVKVLNCD+ITQ K+K+LD VYK +PY
Sbjct: 1461 YSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNCDSITQAKDKLLDTVYKGIPY 1520

Query: 1543 SQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMHYQVSDRSVVALVPKQT 1602
            SQRP+A DMDLEWRQGR+ R++LQDED+TTKIE DWKRLN+L HYQV+D S+VALVPKQ 
Sbjct: 1521 SQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSLVALVPKQV 1580

Query: 1603 SSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLESGVKVWHLVKNHDHGD 1662
            S+YN+  S + +R S+SRY+S  R   SPDSLRSRAPMITPD E+G K+WHLVKNHDH D
Sbjct: 1581 SAYNMANSFTFTR-SLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHLVKNHDHAD 1639

Query: 1663 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETLFSTVHRGSALPLAIKYMFDFLDE 1722
             +EGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFET+FST HRGSALPLAIKYMFDFLDE
Sbjct: 1640 HREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSALPLAIKYMFDFLDE 1699

Query: 1723 QADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKGSITDACLSVVAQTFMDSC 1782
            QAD+  I D DVRHTWKSNCLPLRFWVNVIKNPQFVFDIHK SITDACLSVVAQTFMDSC
Sbjct: 1700 QADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSC 1759

Query: 1783 STSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADIAKLPAISDQDMNAYLAEQSRLHAV 1842
            STSEHRLGKDSPSNKLLYAKDIP+YKSWVERYY DIAK+ +ISDQDM+AYL EQSRLHA 
Sbjct: 1760 STSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDMDAYLVEQSRLHAS 1819

Query: 1843 EFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQRLAYKVEQLINAMSIES 1894
            +F++LSALNE+Y YV+KY +E++ AL++D   R+ +L  K+EQ+I+ +S +S
Sbjct: 1820 DFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISLVSSDS 1871


>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
          Length = 1932

 Score =  966 bits (2496), Expect = 0.0
 Identities = 668/1997 (33%), Positives = 997/1997 (49%), Gaps = 223/1997 (11%)

Query: 5    RPW-PRALEVDSRSVVLLSVVWVLLAPPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVY 63
            RPW P+A  +       L ++ +LL+PP   +     F + N   T NHL +  G G +Y
Sbjct: 33   RPWLPKAPVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAPNT--TLNHLALAPGRGTLY 90

Query: 64   VGAINRVYKLTGNLTIQVAHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSE 123
            VGA+NR+++L+  L ++    TGP  D+  C P      C +   LT+N N+LL++    
Sbjct: 91   VGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQA-QLTDNANQLLLVSSRA 149

Query: 124  NRLLACGSLYQGVCKLLRLDDLF-ILVEPSHKKEHYLSSVNKTGTM-YGVIVRSEGEDGK 181
              L+ACG + QGVC+  RL D+  +L +     +    + N  G    G++V   G D  
Sbjct: 150  QELVACGQVRQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRD-L 208

Query: 182  LFIGTAVDGKQDY-FPTLSSRKLP-RDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHF 239
            L +   + GK     P L+ R+L    P SS  L   +  DF               S +
Sbjct: 209  LLVARGLAGKLSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDF---------------SDY 253

Query: 240  DIFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFG 299
            +  Y+  FA     YF+  +          +     Y S + R+C  D   +SYV +P  
Sbjct: 254  NNSYVGAFADARSAYFVFRRR--------GARAQAEYRSYVARVCLGDTNLYSYVEVPLA 305

Query: 300  CTRAGVEYRLLQAAYLAKPGDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFP 359
            C   G    L+QAA+LA PG               L  +F+ G +        +ALCAFP
Sbjct: 306  CQGQG----LIQAAFLA-PG--------------TLLGVFAAGPRG-----TQAALCAFP 341

Query: 360  IRAINLQIKERLQSCYQGEGN-----LELNWLLGKDVQCTKAPVPIDDNF-CGLDIN-QP 412
            +  +   +++  + CY   G       E     G   +C   P+   +++ CG +    P
Sbjct: 342  MVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSP 401

Query: 413  LGGSTPVEGLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEM 472
            + G  P+E   L    +  +++VA+   +G+ + F+G   G+L K+   G    G  Y  
Sbjct: 402  IAGRQPLEVQPLLKLGQP-VSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQ--GQVYHS 458

Query: 473  VSVLKDGSPILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCA 532
              V   GS I  D+       +LYV++  QV R+PV +C Q+  C  CL + DP CGWC 
Sbjct: 459  QQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCV 518

Query: 533  LHNMCSRRDKCQQAWEPNRFAASISQCVSLAVHPSSISVSEHSRL----LSLVVSDAPDL 588
            L   C+R+ +C +A + N++  S  +  S  +H  S+    H R     ++L V   P L
Sbjct: 519  LQGRCTRKGQCGRAGQLNQWLWSYEED-SHCLHIQSLLPGHHPRQEQGQVTLSVPRLPIL 577

Query: 589  SAG--IACAFGNLTEVEGQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIF 646
             A     CAFG+   +   V G  V C++P    VP+ P   D   + L L  ++     
Sbjct: 578  DADEYFHCAFGDYDSL-AHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDV--TV 634

Query: 647  VSTEFKFYNCSAHQL------CLSCVNSAFRCHWCKYRNLCTH-------DPTTCSFQEG 693
             +T F FY+CSA Q       C +CV S +RCHWC   + C +       + T  S QE 
Sbjct: 635  AATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEV 694

Query: 694  RINISED--CPQLVPTE-EILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRV 750
             I +     CPQ+       L+PVG    + L+ RNL   +     + C L + G +  +
Sbjct: 695  DIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGL 754

Query: 751  PAL----RFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAA 806
            PA       +S  + CQ   + Y  M    L V   V       +DN   L V LY CA 
Sbjct: 755  PATLEETAGDSGLIHCQAHQF-YPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAM 813

Query: 807  QRESCGLCLKADRKFECGWCS-GERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILT 865
                C  C  A+R   C WC+ G+  C     C   +   L        C  P I  +  
Sbjct: 814  GHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEP 865

Query: 866  VSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVGT 925
            ++GPPEGG  +TI G NLG  F+++ + V VA  PC P P  Y  + +IVC    A  GT
Sbjct: 866  LTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGT 925

Query: 926  TSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSV 985
            T GPVR+ I    P     S Q +T+ +P +LSL+P  GP++GGT +TI G +L  G + 
Sbjct: 926  T-GPVRVAIKSQPPGI---SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNT 981

Query: 986  AVYLGNQTCEFYGRSMSE-IVCVSPPSSNGLGPVPVSVSVDRAHVDSNL---QFEYIDDP 1041
            + ++G Q C        E IVC + P +    P   +V V   H    L    F Y  +P
Sbjct: 982  SAFVGGQPCPILEPVCPEAIVCRTRPQA---APGEAAVLVVFGHAQRTLLASPFRYTANP 1038

Query: 1042 RVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNGKESVN---------------- 1085
            ++   EP  S   G   + + G  LDV+Q P + V       V                 
Sbjct: 1039 QLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCG 1098

Query: 1086 ---------------------VCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFN 1124
                                 VC V +++ L C +P++             P    F  +
Sbjct: 1099 APAADPQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAVPDR--------AHPQRVFFTLD 1150

Query: 1125 NVQS--LLIYNDTKFIYYPNPTFELLS---PTGVLDQKPGSPIILKGKNLCPPASGGAKL 1179
            NVQ           F+Y PNP    LS   P      KPG  + ++G+ L     G +K 
Sbjct: 1151 NVQVDFASASGGQGFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGL---NLGISKE 1207

Query: 1180 NYTVLIGETPCAV-TVSETQLLCEPP-------NLTGQHKVMVHVGGMVFSPGSVSVISD 1231
               V IG   C V T++ T L CEPP       N +G  + +V +G +  + G V   ++
Sbjct: 1208 EVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAE 1267

Query: 1232 ---SLLTLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALE 1288
               S   + A   +  G ++L+  V+++ + Y+ KS++     +++ +Q+++LE+ V  +
Sbjct: 1268 PPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQ 1327

Query: 1289 CKEAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQ-- 1346
            C++ F +L T++ +L+SDL+ SGIP+LDYRTYA R  FPG    P+  + E  G      
Sbjct: 1328 CRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCA 1387

Query: 1347 HVEKALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLK 1406
             V + L   + L+N+K+FLLT I TLE Q SFS RDR +VASL+   L G+LEY TD+++
Sbjct: 1388 TVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMR 1447

Query: 1407 QLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIK 1466
             LL DL    +    +PKL+LRRTE++ EK+LTNW +  L+ FL+E AGEPL+ML+ AI+
Sbjct: 1448 TLLGDLAAHYVHR--NPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQ 1505

Query: 1467 QQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLILNC-VNPD------NENSPEIPVKV 1519
             Q++KGP+DA+TG+A+ +L++ +L+R+ +E++ L L   V P       +     +P +V
Sbjct: 1506 YQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARV 1565

Query: 1520 LNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWK 1579
            L+ DTITQVKEK+LD VYK  P+SQRP    +DLEWR G    + L DED+T+  +  WK
Sbjct: 1566 LDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWK 1625

Query: 1580 RLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAP 1639
            RLNTL HY+V D + V LVP+      +   ++IS++   R             L    P
Sbjct: 1626 RLNTLQHYKVPDGATVGLVPQ------LHRGSTISQSLAQRCP-----------LGENIP 1668

Query: 1640 MITPDLESGVKVWHLVKNHDHGD----------QKEGDRGSKMVSEIYLTRLLATKGTLQ 1689
             +    E GV +WHLVK  +  +          ++E  R +K + EIYLTRLL+ KGTLQ
Sbjct: 1669 TLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQ 1727

Query: 1690 KFVDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWV 1749
            KFVDD F+ + S       +P+A+KY+FD LDE A++H I D    H WK+N L LRFWV
Sbjct: 1728 KFVDDTFQAILSV---NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWV 1784

Query: 1750 NVIKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKS 1809
            N +KNPQ +FD+      DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK 
Sbjct: 1785 NALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQ 1844

Query: 1810 WVERYYADIAKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALE 1869
             VERYYADI +    S Q+MN+ LAE S  +    + L AL E+Y+++ +Y +++I ALE
Sbjct: 1845 MVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALE 1904

Query: 1870 QDEQARRQRLAYKVEQL 1886
            +D   ++ +LA +++Q+
Sbjct: 1905 EDPVGQKLQLACRLQQV 1921


>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
          Length = 1909

 Score =  963 bits (2490), Expect = 0.0
 Identities = 663/1980 (33%), Positives = 990/1980 (50%), Gaps = 222/1980 (11%)

Query: 21   LSVVWVLLAPPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQ 80
            L ++ +LL+PP   +     F + N   T NHL +  G G +YVGA+NR+++L+  L ++
Sbjct: 27   LCLLLLLLSPPPLPLTGAHRFSAPNT--TLNHLALAPGRGTLYVGAVNRLFQLSPELQLE 84

Query: 81   VAHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLL 140
                TGP  D+  C P      C +   LT+N N+LL++      L+ACG + QGVC+  
Sbjct: 85   AVAVTGPVIDSPDCVPFRDPAECPQA-QLTDNANQLLLVSSRAQELVACGQVRQGVCETR 143

Query: 141  RLDDLF-ILVEPSHKKEHYLSSVNKTGTM-YGVIVRSEGEDGKLFIGTAVDGKQDY-FPT 197
            RL D+  +L +     +    + N  G    G++V   G D  L +   + GK     P 
Sbjct: 144  RLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRD-LLLVARGLAGKLSAGVPP 202

Query: 198  LSSRKLP-RDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFL 256
            L+ R+L    P SS  L   +  DF               S ++  Y+  FA     YF+
Sbjct: 203  LAIRQLAGSQPFSSEGLGRLVVGDF---------------SDYNNSYVGAFADARSAYFV 247

Query: 257  TVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLA 316
              +          +     Y S + R+C  D   +SYV +P  C   G    L+QAA+LA
Sbjct: 248  FRRR--------GARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA 295

Query: 317  KPGDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQ 376
             PG               L  +F+ G +        +ALCAFP+  +   +++  + CY 
Sbjct: 296  -PG--------------TLLGVFAAGPRG-----TQAALCAFPMVELGASMEQARRLCYT 335

Query: 377  GEGN-----LELNWLLGKDVQCTKAPVPIDDNF-CGLDIN-QPLGGSTPVEGLTLYTTSR 429
              G       E     G   +C   P+   +++ CG +    P+ G  P+E   L    +
Sbjct: 336  AGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQ 395

Query: 430  DRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFS 489
              +++VA+   +G+ + F+G   G+L K+   G    G  Y    V   GS I  D+   
Sbjct: 396  P-VSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQ--GQVYHSQQVGPPGSAISPDLLLD 452

Query: 490  IDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEP 549
                +LYV++  QV R+PV +C Q+  C  CL + DP CGWC L   C+R+ +C +A + 
Sbjct: 453  SSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQL 512

Query: 550  NRFAASISQCVSLAVHPSSISVSEHSRL----LSLVVSDAPDLSAG--IACAFGNLTEVE 603
            N++  S  +  S  +H  S+    H R     ++L V   P L A     CAFG+   + 
Sbjct: 513  NQWLWSYEED-SHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSL- 570

Query: 604  GQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKFYNCSAHQL-- 661
              V G  V C++P    VP+ P   D   + L L  ++      +T F FY+CSA Q   
Sbjct: 571  AHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDV--TVAATNFSFYDCSAVQALE 628

Query: 662  ----CLSCVNSAFRCHWCKYRNLCTH-------DPTTCSFQEGRINISED--CPQLVPTE 708
                C +CV S +RCHWC   + C +       + T  S QE  I +     CPQ+    
Sbjct: 629  AAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGLA 688

Query: 709  -EILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPAL----RFNSSSVQCQ 763
               L+PVG    + L+ RNL   +     + C L + G +  +PA       +S  + CQ
Sbjct: 689  GPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHCQ 748

Query: 764  NSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCLKADRKFEC 823
               + Y  M    L V   V       +DN   L V LY CA     C  C  A+R   C
Sbjct: 749  AHQF-YPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGC 807

Query: 824  GWCS-GERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVN 882
             WC+ G+  C     C   +   L        C  P I  +  ++GPPEGG  +TI G N
Sbjct: 808  LWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEPLTGPPEGGLALTILGSN 859

Query: 883  LGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVGTTSGPVRLCIGECKPEFM 942
            LG  F+++ + V VA  PC P P  Y  + +IVC    A  GTT GPVR+ I    P   
Sbjct: 860  LGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTT-GPVRVAIKSQPPGI- 917

Query: 943  TKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSVAVYLGNQTCEFYGRSMS 1002
              S Q +T+ +P +LSL+P  GP++GGT +TI G +L  G + + ++G Q C        
Sbjct: 918  --SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCP 975

Query: 1003 E-IVCVSPPSSNGLGPVPVSVSVDRAHVDSNL---QFEYIDDPRVQRIEPEWSIASGHTP 1058
            E IVC + P +    P   +V V   H    L    F Y  +P++   EP  S   G   
Sbjct: 976  EAIVCRTRPQA---APGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRL 1032

Query: 1059 LTITGFNLDVIQEPRIRVKFNGKESVN--------------------------------- 1085
            + + G  LDV+Q P + V       V                                  
Sbjct: 1033 IRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLL 1092

Query: 1086 ----VCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQS--LLIYNDTKFIY 1139
                VC V +++ L C +P++             P    F  +NVQ           F+Y
Sbjct: 1093 QCSTVCSVNSSSLLLCRSPAVPDR--------AHPQRVFFTLDNVQVDFASASGGQGFLY 1144

Query: 1140 YPNPTFELLS---PTGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGETPCAV-TVS 1195
             PNP    LS   P      KPG  + ++G+ L     G +K    V IG   C V T++
Sbjct: 1145 QPNPRLAPLSREGPARPYRLKPGHVLDVEGEGL---NLGISKEEVRVHIGRGECLVKTLT 1201

Query: 1196 ETQLLCEPP-------NLTGQHKVMVHVGGMVFSPGSVSVISD---SLLTLPAIVSIAAG 1245
             T L CEPP       N +G  + +V +G +  + G V   ++   S   + A   +  G
Sbjct: 1202 RTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMG 1261

Query: 1246 GSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECKEAFAELQTDINELTS 1305
             ++L+  V+++ + Y+ KS++     +++ +Q+++LE+ V  +C++ F +L T++ +L+S
Sbjct: 1262 AAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSS 1321

Query: 1306 DLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQ--HVEKALKLFAQLINNKV 1363
            DL+ SGIP+LDYRTYA R  FPG    P+  + E  G       V + L   + L+N+K+
Sbjct: 1322 DLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKL 1381

Query: 1364 FLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLENKNHP 1423
            FLLT I TLE Q SFS RDR +VASL+   L G+LEY TD+++ LL DL    +    +P
Sbjct: 1382 FLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHR--NP 1439

Query: 1424 KLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARY 1483
            KL+LRRTE++ EK+LTNW +  L+ FL+E AGEPL+ML+ AI+ Q++KGP+DA+TG+A+ 
Sbjct: 1440 KLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKR 1499

Query: 1484 SLSEDKLIRQQIEYKTLILNC-VNPD------NENSPEIPVKVLNCDTITQVKEKILDAV 1536
            +L++ +L+R+ +E++ L L   V P       +     +P +VL+ DTITQVKEK+LD V
Sbjct: 1500 TLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQV 1559

Query: 1537 YKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMHYQVSDRSVVA 1596
            YK  P+SQRP    +DLEWR G    + L DED+T+  +  WKRLNTL HY+V D + V 
Sbjct: 1560 YKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVG 1619

Query: 1597 LVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLESGVKVWHLVK 1656
            LVP+      +   ++IS++   R             L    P +    E GV +WHLVK
Sbjct: 1620 LVPQ------LHRGSTISQSLAQRCP-----------LGENIPTLEDGEEGGVCLWHLVK 1662

Query: 1657 NHDHGD----------QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETLFSTVHRG 1706
              +  +          ++E  R +K + EIYLTRLL+ KGTLQKFVDD F+ + S     
Sbjct: 1663 ATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV---N 1718

Query: 1707 SALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKGSI 1766
              +P+A+KY+FD LDE A++H I D    H WK+N L LRFWVN +KNPQ +FD+     
Sbjct: 1719 RPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDN 1778

Query: 1767 TDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADIAKLPAISD 1826
             DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK  VERYYADI +    S 
Sbjct: 1779 VDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASY 1838

Query: 1827 QDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQRLAYKVEQL 1886
            Q+MN+ LAE S  +    + L AL E+Y+++ +Y +++I ALE+D   ++ +LA +++Q+
Sbjct: 1839 QEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQV 1898


>gi|149363636 plexin B2 [Homo sapiens]
          Length = 1838

 Score =  924 bits (2387), Expect = 0.0
 Identities = 633/1940 (32%), Positives = 990/1940 (51%), Gaps = 197/1940 (10%)

Query: 27   LLAPPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQVAHKTG 86
            LL   A+  P+   F    ++   NHL V + +G VY+GA+N +Y+L   L ++    TG
Sbjct: 13   LLGAGASLRPRKLDFFRSEKE--LNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATG 70

Query: 87   PEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLF 146
            P  DNK C PP+    C E   +T+NVN+LL++D    RL+ CGSL++G+C L  L ++ 
Sbjct: 71   PALDNKKCTPPIEASQCHEA-EMTDNVNQLLLLDPPRKRLVECGSLFKGICALRALSNIS 129

Query: 147  ILV---EPSHKKEHYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKL 203
            + +   + S +K    S+     T+  V     G D  LF+G   +G  D    +S+R L
Sbjct: 130  LRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKG-NGPHDNGIIVSTRLL 188

Query: 204  PRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPETP 263
             R     A   Y  H+ + +  +   +            ++  F  G +V+F+  Q +  
Sbjct: 189  DRTDSREAFEAYTDHATYKAGYLSTNTQQ----------FVAAFEDGPYVFFVFNQQD-- 236

Query: 264  EGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPGDSLA 323
            +  A N        + + R+C++DP ++SY+ +   C    +        + A  G  LA
Sbjct: 237  KHPARNR-------TLLARMCREDPNYYSYLEMDLQCRDPDI--------HAAAFGTCLA 281

Query: 324  QAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLEL 383
             +        VL+A+FS+  +    P   + LC FP+  ++ +++    +CY G    E 
Sbjct: 282  ASVAAPGSGRVLYAVFSRDSRSSGGP--GAGLCLFPLDKVHAKMEANRNACYTG--TREA 337

Query: 384  NWLLGK----DVQCT-KAPVPIDDNFCGLD-INQPLGGSTPVEGLTLYTTSRDRMTSVAS 437
              +  K    D+QC   AP       CG + +  PLG    + G  +       +T+V  
Sbjct: 338  RDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTV 397

Query: 438  YVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQRYLYV 497
               N ++V F+GT  G++ K+    P     +Y+ + V +    + RD+  S D   LY 
Sbjct: 398  AAENNHTVAFLGTSDGRILKVYLT-PDGTSSEYDSILV-EINKRVKRDLVLSGDLGSLYA 455

Query: 498  MSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEPNRFAASIS 557
            M++ +V R+PV+ C  Y TC +C  S DP+CGWC +   C+R+ +C +A E + +  S S
Sbjct: 456  MTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRS 515

Query: 558  Q-CVSL-AVHPSSISVSEHSRLLSLVVSDAPDLSAG--IACAFGNLTEVEGQVSGSQVIC 613
            + CV++ +  P ++S      +  L VS  P LS    + C FG       +V G  VIC
Sbjct: 516  KSCVAVTSAQPQNMSRRAQGEV-QLTVSPLPALSEEDELLCLFGESPPHPARVEGEAVIC 574

Query: 614  ISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKFYNC------SAHQLCLSCVN 667
             SP    +PV P  QD   + +QL  +       S ++ FY+C        +  C+SCV+
Sbjct: 575  NSPS--SIPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISCVS 632

Query: 668  SAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLVPTEEILIPVGEVKPITLKARNL 727
            + + C W    + C            R ++ + CPQ +    ++IP+     +  + +NL
Sbjct: 633  NRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETDVNFQGKNL 692

Query: 728  PQPQSGQRGYECVLNIQGAIHRV--PALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVW 785
               +         L++   + +   P     S +   +     +D  +   L +   V  
Sbjct: 693  DTVKGSS------LHVGSDLLKFMEPVTMQESGTFAFRTPKLSHDANE--TLPLHLYVKS 744

Query: 786  NGNFIIDNPQDLKVH--LYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSS 843
             G  I     D K+H  LY C+  R  C LC  A+  + C WC G+ RC     C + S 
Sbjct: 745  YGKNI-----DSKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALCNTTS- 798

Query: 844  PWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTP 903
                      +C  P IT I   +GP  GG R+TI G NLG+   +I   + VAG  C+ 
Sbjct: 799  ----------ECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDI-QRISVAGRNCSF 847

Query: 904  LPGEYIIAEQIVCEMGHALVGTTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIR 963
             P  Y ++ +IVC +  A    T G      G+      +  + Q+TF  P  LS+ P +
Sbjct: 848  QPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLG---RSPPNVQFTFQQPKPLSVEPQQ 904

Query: 964  GPESGGTMVTITGHYLGAGSS--VAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPVS 1021
            GP++GGT +TI G +L  GS   V V L    C+   +  +++ CV+ P +   G + + 
Sbjct: 905  GPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVT-KFGAQLQCVTGPQATR-GQMLLE 962

Query: 1022 VSVDRAHVDS-NLQFEYIDDPRVQRIEPEWSIASGHTPLTITG--------FNLDVIQEP 1072
            VS   + V +  + F Y ++P ++  EP  S ASG   + +TG        F + VI EP
Sbjct: 963  VSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIAEP 1022

Query: 1073 -RIRVKFNGKESVNVCKVVNT-------TTLTCLAPSLTTDYRPGLDTVERPDEFGFV-- 1122
             +        ES+    VV T       T +  L+P++           E P+ +     
Sbjct: 1023 LQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVP----------EEPEAYNLTVL 1072

Query: 1123 --FNNVQSLLIYNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLN 1180
               +  ++LL      F Y P+PTFE    TG + ++    I  +G NL    +      
Sbjct: 1073 IEMDGHRALLRTEAGAFEYVPDPTFENF--TGGVKKQVNKLIHARGTNLNKAMT---LQE 1127

Query: 1181 YTVLIGETPCAV-TVSETQLLCEPPNLTGQHK-------------VMVHVGGMVFSPGSV 1226
                +G   C + T++ET L CEPP +    K              +V  G   +  G V
Sbjct: 1128 AEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRV 1187

Query: 1227 SV---ISDSLLTLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLES 1283
                 +SD  L+L   + I      +++++ + +  Y RKS++ +   ++++ Q++ LE 
Sbjct: 1188 EYDTRVSDVPLSLILPLVIVP----MVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEE 1243

Query: 1284 RVALECKEAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLF----PGIEDHPVLRELE 1339
             V   CK+ F +L  ++ + T+D+  +GIP LDY+TY  RV F     G +D  +  +L+
Sbjct: 1244 SVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLD 1303

Query: 1340 VQGNGQQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLE 1399
            +    +  VE+AL  F+ L+N+K FL+ FI TLE QR FS R +   ASL+   L G+LE
Sbjct: 1304 IPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLE 1363

Query: 1400 YATDVLKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLF 1459
            Y TD++  L  +L+++ +  KN PKL+LRR+E+V E+ML+NW +  L+++LK+ AGEPL+
Sbjct: 1364 YYTDIMHTLFLELLEQYVVAKN-PKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLY 1422

Query: 1460 MLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLILNCVNPDNENSPEIPVKV 1519
             L+ AIK Q+EKGP+DA+  +A+Y+L++  L+   +EY  L ++ +  D E    IPVKV
Sbjct: 1423 KLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIVQD-EGVDAIPVKV 1481

Query: 1520 LNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWK 1579
            LNCDTI+QVKEKI+D VY+  P S  PR   + LEWR G  A++ L D D+T++ EG WK
Sbjct: 1482 LNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQI-LSDLDLTSQREGRWK 1540

Query: 1580 RLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISRY--DSSFRYTGSPDSLRSR 1637
            R+NTLMHY V D + + L                S+  +S+   DS     G   +L   
Sbjct: 1541 RVNTLMHYNVRDGATLIL----------------SKVGVSQQPEDSQQDLPGERHAL--- 1581

Query: 1638 APMITPDLESGVKVWHLVKNHDHGDQKEGDRGS-------KMVSEIYLTRLLATKGTLQK 1690
                   LE   +VWHLV+  D  D+ +  RGS       K ++EIYLTRLL+ KGTLQ+
Sbjct: 1582 -------LEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTRLLSVKGTLQQ 1634

Query: 1691 FVDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVN 1750
            FVD+ F+++ +  H   A+P A+KY FDFLDEQA++H+I D D  H WK+N LPLRFWVN
Sbjct: 1635 FVDNFFQSVLAPGH---AVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFWVN 1691

Query: 1751 VIKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSW 1810
            ++KNP F+FD+H   + DA LSV+AQTFMD+C+ +EH+L +DSPSNKLLYAK+I +YK  
Sbjct: 1692 ILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKM 1751

Query: 1811 VERYYADIAKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQ 1870
            VE YY  I ++  +SDQDMN +LAE SR H    N L AL+++Y Y  KY +E+I ALE+
Sbjct: 1752 VEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEE 1811

Query: 1871 DEQARRQRLAYKVEQLINAM 1890
            D  A++ +LA++++Q+  A+
Sbjct: 1812 DPAAQKMQLAFRLQQIAAAL 1831


>gi|157694524 plexin D1 [Homo sapiens]
          Length = 1925

 Score =  889 bits (2296), Expect = 0.0
 Identities = 638/1951 (32%), Positives = 972/1951 (49%), Gaps = 207/1951 (10%)

Query: 51   NHLTVHQGTGAVYVGAINRVYKLTG-NLTIQVAHKTGPEEDNKSCYPPLIVQP-CSEVLT 108
            N+  +    G VY+ A+NR+Y+L+G NL+++     GP  D+  C+ P + Q  C     
Sbjct: 60   NNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRR 119

Query: 109  LTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLFILV-------EPSHKKEHYLSS 161
            LT+N NK+L +D  +  ++ CGS+YQG C+L R  ++  +         P+     + S 
Sbjct: 120  LTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSM 179

Query: 162  VN------KTGTMYGVIVRSEGEDG-KLFIGTAVDGK-QDYFP---TLSSRKLPRDPESS 210
            +N         T+  V+  + G  G +L +G    G    +FP   +L   +    PE +
Sbjct: 180  LNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIA 239

Query: 211  AM-LDY--ELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPETPEG-- 265
               LD   +L   F   L     + L +       +  GF S     FL      P    
Sbjct: 240  IRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSA----FLHPSDPPPGAQS 295

Query: 266  ---VAINS---AGDLFYTSR--IVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYL-- 315
               +A+NS   AGD    +R  + R+C           LP G   AG + + L  +Y+  
Sbjct: 296  YAYLALNSEARAGDKESQARSLLARIC-----------LPHG---AGGDAKKLTESYIQL 341

Query: 316  -------AKPGDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIK 368
                   A  GD  ++  ++    + LFA+F + Q         +ALCAF    +   I+
Sbjct: 342  GLQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIR 401

Query: 369  ERLQSCYQGEGNLELNWLLGKDVQCTKAPVPIDDNF--------CGL-DINQPLGGSTPV 419
                +C+  E   ++  +L   VQ T        N         CG   +  PL    P+
Sbjct: 402  AARTACFV-EPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPL 460

Query: 420  EGLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDG 479
            +   ++      +TSVA    N Y+ VF+GT +G+L KI  +      V    V  +  G
Sbjct: 461  KATPVFRAPG--LTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQ--VVSRRVVTVAYG 516

Query: 480  SPILRDMAFS-IDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCS 538
             P+   M F   D  YLY+M+  Q+ RV V +C  ++TCG+C+ + D +CGWCAL   C+
Sbjct: 517  EPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCT 576

Query: 539  RRDKCQQAWEPNRFAASI---SQCVSLAVHPSSISV-SEHSRLLSLVVSDAPDLSA-GIA 593
             +  C  + + + + ++    S+C ++ V PS I V  E+  ++  +    P LS   +A
Sbjct: 577  LQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGMEMA 636

Query: 594  CAFGN----LTEVEGQVSGSQVICISPGPKD-VPVIPLDQDWFGLELQLRSKETGKIFVS 648
            C +GN    +  V G   G Q+   +  P+D  P  P +QD   +E+ +R    G+  V 
Sbjct: 637  CDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVRVN--GRNIVK 694

Query: 649  TEFKFYNCSA------HQLCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCP 702
              F  Y+CS       H  C SC+++ + C WC  ++ C  + + C       +  +DCP
Sbjct: 695  ANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNPTS-PQDCP 753

Query: 703  QLVPTEEILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQC 762
            + + +    +P G  + I +   N    Q      EC   ++       A+  N S V+C
Sbjct: 754  RTLLSPLAPVPTGGSQNILVPLANTAFFQGA--ALECSFGLEEIFE---AVWVNESVVRC 808

Query: 763  QNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCL-KADRKF 821
             +    +         +   +       +D+P+ + V +Y CA     C  CL + D   
Sbjct: 809  -DQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQCLGREDLGH 867

Query: 822  ECGWCSGERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGV 881
             C W  G   C L      P  P          C  P+I  I  +SGP +GGT +TI G 
Sbjct: 868  LCMWSDG---CRLR----GPLQPMAG------TCPAPEIRAIEPLSGPLDGGTLLTIRGR 914

Query: 882  NLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVGTTSGPVRLCIGECKPEF 941
            NLG   S++AH V + GV C PLP  Y ++E+IVC  G A  G  SG V +   +     
Sbjct: 915  NLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPA-PGPLSGVVTVNASK----- 968

Query: 942  MTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSVAVYLGN-QTCEFYGRS 1000
              KS  ++++V P V SL P  GP++GGT +TI G+ L  GS + V + +   C    R+
Sbjct: 969  EGKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRT 1028

Query: 1001 MSEIVCVSPPSSNGLGPVPVSVSVDRAH-VDSNLQFEYIDDPRVQRIEPEWSIASGHTPL 1059
             + I C  P  +    PVPV V  +R   V  NL F Y+ +P +  I P  S  SG   +
Sbjct: 1029 DTSIACTMPEGALP-APVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTI 1087

Query: 1060 TITGFNLDVIQEPRIRVKFNGKESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEF 1119
            T+ G    ++Q   + V   G+E   +CKV+N+T +TC +P   ++    +D       +
Sbjct: 1088 TVAGERFHMVQNVSMAVHHIGREPT-LCKVLNSTLITCPSPGALSNASAPVDFFINGRAY 1146

Query: 1120 GFVFNNVQSLLIYNDT------KFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCPPA 1173
                   + LL   +       +  Y PNP F        +   PG P+ L        +
Sbjct: 1147 ADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKE-QDS 1205

Query: 1174 SGGAKLNYTVLIGETPCAVTVSETQLLCEPPN-----LTGQHKVMVHVGGMVFSPGSVSV 1228
             G     Y V IG+  C + +   +++    N       GQ  + + VG    +  ++ +
Sbjct: 1206 LGLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQTIATLQL 1265

Query: 1229 ISDSLLTLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALE 1288
                   + +IV      S+LL++ ++ L  +  KSR  +   ++  +QM+ +ES++  E
Sbjct: 1266 GGSETAIIVSIVIC----SVLLLLSVVALFVFCTKSRRAERYWQKTLLQMEEMESQIREE 1321

Query: 1289 CKEAFAELQTDINELTSDLDRS-GIPYLDYRTYAMRVLFPGI------------------ 1329
             ++ FAELQTD+ +LT +L+RS GIP+L+Y+ +  R  FP                    
Sbjct: 1322 IRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQ 1381

Query: 1330 ------EDHPVLRELEVQGNGQQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSMRDR 1383
                  E HP+L E ++  + + ++E+ + LF+ L+NNK FL+ F+  LE Q+ F++RDR
Sbjct: 1382 GSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDR 1441

Query: 1384 GNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTNWFA 1443
             ++ASL+   L G+LEY T ++K+LL DLID +     +PKL+LRRTESV EKMLTNW +
Sbjct: 1442 CSLASLLTIALHGKLEYYTSIMKELLVDLIDASAAK--NPKLMLRRTESVVEKMLTNWMS 1499

Query: 1444 FLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLILN 1503
              ++  L+E  GEP F+L CAIKQQ+ KG IDAITG+ARY+L+E+ L+R+ IE K   LN
Sbjct: 1500 ICMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLN 1559

Query: 1504 CVNPDNENSPEIPVKVLNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARV 1563
             V+        + V+ ++ DT+TQVKEKIL+A  KNVPYSQ PRA D+DLEW        
Sbjct: 1560 -VSFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSY 1618

Query: 1564 VLQDEDITTKIEGDWKRLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISRYDS 1623
            +L+D D T+ +E   K+LNTL HY+                  IP  AS++ + I + D+
Sbjct: 1619 ILRDLDDTSVVEDGRKKLNTLAHYK------------------IPEGASLAMSLIDKKDN 1660

Query: 1624 SFRYTGSPDSLRSRAPMITPDLESGVKVWHLVKNHDH-GDQKEGDRGS---KMVSEIYLT 1679
            +       D+                K +HLV   D   + K+  R S   K++ EIYLT
Sbjct: 1661 TLGRVKDLDT---------------EKYFHLVLPTDELAEPKKSHRQSHRKKVLPEIYLT 1705

Query: 1680 RLLATKGTLQKFVDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWK 1739
            RLL+TKGTLQKF+DDLF+ + S   R    PLA+KY FDFL+EQA++  I D D  H WK
Sbjct: 1706 RLLSTKGTLQKFLDDLFKAILSI--REDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWK 1763

Query: 1740 SNCLPLRFWVNVIKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLL 1799
            +N LPLRFWVN++KNPQFVFDI K    DACLSV+AQ F+D+CS S+ +LGKDSP+NKLL
Sbjct: 1764 TNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLL 1823

Query: 1800 YAKDIPSYKSWVERYYADIAKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSK 1859
            YAK+IP Y+  V+RYY  I  +  +S+Q+MNA+LAE+SR +  EFN   A+ EIY Y  +
Sbjct: 1824 YAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKR 1883

Query: 1860 YSEELIGALEQDEQARRQRLAYKVEQLINAM 1890
            Y  +++ ALE +  ARR +L +K EQ++  M
Sbjct: 1884 YRPQIMAALEANPTARRTQLQHKFEQVVALM 1914


>gi|194272180 plexin B1 [Homo sapiens]
          Length = 2135

 Score =  788 bits (2036), Expect = 0.0
 Identities = 488/1272 (38%), Positives = 695/1272 (54%), Gaps = 132/1272 (10%)

Query: 698  SEDCPQLVPTE-EILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPAL--- 753
            +  CP +   +   L+PV   + I L  RNL   Q G    ECV+ ++G    V A    
Sbjct: 910  ASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVEC 969

Query: 754  ---RFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRES 810
                     V CQ     Y+ +    L V   +   G   +D+ + L V LY C+     
Sbjct: 970  EPPPDTQCHVTCQQHQLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGD 1028

Query: 811  CGLCLKADRKFECGWCSGER-RCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGP 869
            C  C  A  ++ C WC GER RC   + C    +          +C  P I  +  ++GP
Sbjct: 1029 CSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAV-------ATQCPAPLIHSVEPLTGP 1081

Query: 870  PEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVC---EMGHALVGTT 926
             +GGTRVTI G NLG    ++   V VAGVPC     EY ++  +VC     G  + G T
Sbjct: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141

Query: 927  SGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAG--SS 984
            +        E        S   + + +P V S+ P RGP +GGT +T+ G  L  G    
Sbjct: 1142 AV-------EVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLED 1194

Query: 985  VAVYLGNQTCEFYGRSMSE-IVCVSPPSSNGLGPVPVSVSVDRAHVDSNLQ---FEYIDD 1040
            + V +G+Q C       SE + C + P      P  + V+V     +  LQ   F+Y  D
Sbjct: 1195 IRVVVGDQPCHLLPEQQSEQLRCETSPRPT---PATLPVAVWFGATERRLQRGQFKYTLD 1251

Query: 1041 PRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKF---------------------- 1078
            P +    P  S  SG   + + G NLDV+Q PRIRV                        
Sbjct: 1252 PNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETA 1311

Query: 1079 -------NGKESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERP-DEFGFVFNN-VQSL 1129
                   + ++    C V ++  +TC  P+L     PGL   E P     F+ +N V   
Sbjct: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPAL-----PGLP--EDPWVRVEFILDNLVFDF 1364

Query: 1130 LIYNDTKFIYYPNPTFELLSP---TGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIG 1186
               N T F Y  +PT + L+P   T     KPGS   ++G+NL    S   K     +IG
Sbjct: 1365 ATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMS---KEEVVAMIG 1421

Query: 1187 ETPCAV-TVSETQLLCEPP---NLTGQHKVM----------VHVGGMVFSPGSVSVISDS 1232
            + PC V T++   L CEPP    L   H +           V +G + FS G V    +S
Sbjct: 1422 DGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGES 1481

Query: 1233 LLTLP--AIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECK 1290
                P  A V +  G SLL + VII+++ Y+RKS++     K++Q+Q++NLES V   CK
Sbjct: 1482 PGAFPVAAQVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCK 1541

Query: 1291 EAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQHVEK 1350
            + F +L T++ +LTSDL  SGIP+LDY+ YA R+ FPG  + P+ R+L V  + +  VE+
Sbjct: 1542 KEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQ 1601

Query: 1351 ALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLS 1410
             L   + L+N+K+FL  FI TLE QR+FS RDR  VASL+   L G+LEY TD+L+ LLS
Sbjct: 1602 GLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLS 1661

Query: 1411 DLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQME 1470
            DL+ + +    +PKL+LRRTE+V EK+LTNW +  L+ F+++  GEPL+ML+  IK Q++
Sbjct: 1662 DLVAQYVAK--NPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVD 1719

Query: 1471 KGPIDAITGEARYSLSEDKLIRQQIEYKTLILNC---VNPDNENSPEIPVKVLNCDTITQ 1527
            KGP+D++TG+A+Y+L++++L+R+ +EY+ L LN    V P    +  +PVKVL+CDTI+Q
Sbjct: 1720 KGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQ 1779

Query: 1528 VKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMHY 1587
             KEK+LD +YK VP +QRP    +D+EWR G    ++L DED+T++++G W+RLNTL HY
Sbjct: 1780 AKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHY 1839

Query: 1588 QVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLES 1647
            +V D + VALVP  T               + R +  +           R PM+    E 
Sbjct: 1840 KVPDGATVALVPCLTKH-------------VLRENQDY-------VPGERTPMLEDVDEG 1879

Query: 1648 GVKVWHLVKNHDHGDQKEGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFET 1698
            G++ WHLVK  D  +     RGS         K + EIYLTRLL+ KGTLQKFVDDLF+ 
Sbjct: 1880 GIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQV 1939

Query: 1699 LFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFV 1758
            + ST      +PLA+KY FD LDEQA +H I D D  H WK+N LPLRFW+N+IKNPQFV
Sbjct: 1940 ILST---SRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFV 1996

Query: 1759 FDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADI 1818
            FD+      DA L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK  VERYYADI
Sbjct: 1997 FDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADI 2056

Query: 1819 AKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQR 1878
             +    SDQ+MN+ LAE S  ++ +     AL+E+Y Y++KY +++I ALE+D  A++ +
Sbjct: 2057 RQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQ 2116

Query: 1879 LAYKVEQLINAM 1890
            L Y+++Q+  A+
Sbjct: 2117 LGYRLQQIAAAV 2128



 Score =  275 bits (702), Expect = 4e-73
 Identities = 218/745 (29%), Positives = 345/745 (46%), Gaps = 89/745 (11%)

Query: 25  WVLLA---PPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQV 81
           WVL     PP A  P  +      RD T         +G +Y+GA N +++L+  L ++ 
Sbjct: 16  WVLTLQPLPPTAFTPNGTYLQHLARDPT---------SGTLYLGATNFLFQLSPGLQLEA 66

Query: 82  AHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLR 141
              TGP  D++ C PP++   C +    TNN N+LL++  S   L+ CGS++QGVC+  R
Sbjct: 67  TVSTGPVLDSRDCLPPVMPDECPQAQP-TNNPNQLLLV--SPGALVVCGSVHQGVCEQRR 123

Query: 142 LDDLF-ILVEPSHKKE-HYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVD--GKQDYFPT 197
           L  L  +L+ P    +  Y+++ +   +  G++ +    +  LF+G      G     P 
Sbjct: 124 LGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPP 183

Query: 198 LSSRKL-PRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFL 256
           +++R L P DP+  A   YE          K+    L+  SH    ++  FA G   YFL
Sbjct: 184 ITTRALWPPDPQ--AAFSYE-------ETAKLAVGRLSEYSHH---FVSAFARGASAYFL 231

Query: 257 TVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLA 316
            ++ +         A    + + + R+C  D  ++SYV LP  C   G  Y L+QAA +A
Sbjct: 232 FLRRDL-------QAQSRAFRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQAAAVA 282

Query: 317 KPGDSLAQAFNITSQDDVLFAIFSKGQKQ-YHHPPDD-------SALCAFPIRAINLQIK 368
              +         +  +VLFA FS         PP         SALCAFP+  ++    
Sbjct: 283 TSRE--------VAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLAN 334

Query: 369 ERLQSCYQGEGNLE-------LNWLLGKDVQCTKAPVPIDDNF-CGLDIN-QPLGGSTPV 419
               +CY  EG  E       + + +  D  C + PV   D + CG D    P+    P+
Sbjct: 335 RTRDACYTREGRAEDGTEVAYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMASRVPL 392

Query: 420 EGLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDG 479
           E   +      ++T+VA  + +G+++ F+G   G+L ++   GP   G  Y   S+ + G
Sbjct: 393 EATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYL-GPGSDGHPYSTQSI-QQG 450

Query: 480 SPILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSR 539
           S + RD+ F     +LYVM++  + +VPV SC Q+  C  CL+  DP+CGWC L   CSR
Sbjct: 451 SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSR 510

Query: 540 RDKCQQAWEPNRFAASISQ---CVSL-AVHPSSISVSEHSRLLSLVVSDAPDLSAG--IA 593
           R +C +   P ++  S      C+ + A+ P++IS  E +R + L V D P L  G   +
Sbjct: 511 RSECSRGQGPEQWLWSFQPELGCLQVAAMSPANIS-REETREVFLSVPDLPPLWPGESYS 569

Query: 594 CAFGNLTEVEGQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKF 653
           C FG   +    ++GS V+C SP P + PV+P   D+  + ++LR      +   T   F
Sbjct: 570 CHFGE-HQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAV--VIAKTSLSF 626

Query: 654 YNCSA------HQLCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLVPT 707
           Y+C A         C +CV+S + C+WC +++LCTH     S   G +  S   P + P 
Sbjct: 627 YDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCTH---KASCDAGPMVASHQSPLVSPD 683

Query: 708 EEILIPVGEVKPITLKARNLPQPQS 732
                      P   KA   P P +
Sbjct: 684 PPARGGPSPSPPTAPKALATPAPDT 708



 Score = 35.4 bits (80), Expect = 0.53
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 20/114 (17%)

Query: 744 QGAIHRV------PALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDL 797
           QG +HRV          +++ S+Q Q S+   D        + F   +   +++     L
Sbjct: 425 QGQLHRVYLGPGSDGHPYSTQSIQ-QGSAVSRD--------LTFDGTFEHLYVMTQSTLL 475

Query: 798 KVHLYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSSP--WLDWS 849
           KV +  CA Q   C  CL A R   CGWC    RC+    C+    P  WL WS
Sbjct: 476 KVPVASCA-QHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWL-WS 526



 Score = 35.0 bits (79), Expect = 0.70
 Identities = 48/203 (23%), Positives = 72/203 (35%), Gaps = 36/203 (17%)

Query: 655 NCSAHQLCLSCVNSAFR---CHWCKYRNLCTHDPTTCSFQEG------RINISEDCPQLV 705
           +C+ H  C SC+  A R   C WC     C+   + CS  +G             C Q+ 
Sbjct: 481 SCAQHLDCASCL--AHRDPYCGWCVLLGRCSRR-SECSRGQGPEQWLWSFQPELGCLQVA 537

Query: 706 PTEEILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQNS 765
                 I   E + + L   +LP    G+  Y C        H+ PAL    S V C + 
Sbjct: 538 AMSPANISREETREVFLSVPDLPPLWPGE-SYSCHFGE----HQSPAL-LTGSGVMCPSP 591

Query: 766 SYQYD-----GMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRE-----SCGLCL 815
                     G D  +++V+      G  +I       +  Y C A  E      C  C+
Sbjct: 592 DPSEAPVLPRGADYVSVSVELRF---GAVVIAKTS---LSFYDCVAVTELRPSAQCQACV 645

Query: 816 KADRKFECGWCSGERRCTLHQHC 838
            +  ++ C WC  +  CT    C
Sbjct: 646 SS--RWGCNWCVWQHLCTHKASC 666


>gi|40254442 plexin B1 [Homo sapiens]
          Length = 2135

 Score =  788 bits (2036), Expect = 0.0
 Identities = 488/1272 (38%), Positives = 695/1272 (54%), Gaps = 132/1272 (10%)

Query: 698  SEDCPQLVPTE-EILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPAL--- 753
            +  CP +   +   L+PV   + I L  RNL   Q G    ECV+ ++G    V A    
Sbjct: 910  ASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVEC 969

Query: 754  ---RFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRES 810
                     V CQ     Y+ +    L V   +   G   +D+ + L V LY C+     
Sbjct: 970  EPPPDTQCHVTCQQHQLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGD 1028

Query: 811  CGLCLKADRKFECGWCSGER-RCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGP 869
            C  C  A  ++ C WC GER RC   + C    +          +C  P I  +  ++GP
Sbjct: 1029 CSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAV-------ATQCPAPLIHSVEPLTGP 1081

Query: 870  PEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVC---EMGHALVGTT 926
             +GGTRVTI G NLG    ++   V VAGVPC     EY ++  +VC     G  + G T
Sbjct: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141

Query: 927  SGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAG--SS 984
            +        E        S   + + +P V S+ P RGP +GGT +T+ G  L  G    
Sbjct: 1142 AV-------EVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLED 1194

Query: 985  VAVYLGNQTCEFYGRSMSE-IVCVSPPSSNGLGPVPVSVSVDRAHVDSNLQ---FEYIDD 1040
            + V +G+Q C       SE + C + P      P  + V+V     +  LQ   F+Y  D
Sbjct: 1195 IRVVVGDQPCHLLPEQQSEQLRCETSPRPT---PATLPVAVWFGATERRLQRGQFKYTLD 1251

Query: 1041 PRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKF---------------------- 1078
            P +    P  S  SG   + + G NLDV+Q PRIRV                        
Sbjct: 1252 PNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETA 1311

Query: 1079 -------NGKESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERP-DEFGFVFNN-VQSL 1129
                   + ++    C V ++  +TC  P+L     PGL   E P     F+ +N V   
Sbjct: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPAL-----PGLP--EDPWVRVEFILDNLVFDF 1364

Query: 1130 LIYNDTKFIYYPNPTFELLSP---TGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIG 1186
               N T F Y  +PT + L+P   T     KPGS   ++G+NL    S   K     +IG
Sbjct: 1365 ATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMS---KEEVVAMIG 1421

Query: 1187 ETPCAV-TVSETQLLCEPP---NLTGQHKVM----------VHVGGMVFSPGSVSVISDS 1232
            + PC V T++   L CEPP    L   H +           V +G + FS G V    +S
Sbjct: 1422 DGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGES 1481

Query: 1233 LLTLP--AIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECK 1290
                P  A V +  G SLL + VII+++ Y+RKS++     K++Q+Q++NLES V   CK
Sbjct: 1482 PGAFPVAAQVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCK 1541

Query: 1291 EAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQHVEK 1350
            + F +L T++ +LTSDL  SGIP+LDY+ YA R+ FPG  + P+ R+L V  + +  VE+
Sbjct: 1542 KEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQ 1601

Query: 1351 ALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLS 1410
             L   + L+N+K+FL  FI TLE QR+FS RDR  VASL+   L G+LEY TD+L+ LLS
Sbjct: 1602 GLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLS 1661

Query: 1411 DLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQME 1470
            DL+ + +    +PKL+LRRTE+V EK+LTNW +  L+ F+++  GEPL+ML+  IK Q++
Sbjct: 1662 DLVAQYVAK--NPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVD 1719

Query: 1471 KGPIDAITGEARYSLSEDKLIRQQIEYKTLILNC---VNPDNENSPEIPVKVLNCDTITQ 1527
            KGP+D++TG+A+Y+L++++L+R+ +EY+ L LN    V P    +  +PVKVL+CDTI+Q
Sbjct: 1720 KGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQ 1779

Query: 1528 VKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMHY 1587
             KEK+LD +YK VP +QRP    +D+EWR G    ++L DED+T++++G W+RLNTL HY
Sbjct: 1780 AKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHY 1839

Query: 1588 QVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLES 1647
            +V D + VALVP  T               + R +  +           R PM+    E 
Sbjct: 1840 KVPDGATVALVPCLTKH-------------VLRENQDY-------VPGERTPMLEDVDEG 1879

Query: 1648 GVKVWHLVKNHDHGDQKEGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFET 1698
            G++ WHLVK  D  +     RGS         K + EIYLTRLL+ KGTLQKFVDDLF+ 
Sbjct: 1880 GIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQV 1939

Query: 1699 LFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFV 1758
            + ST      +PLA+KY FD LDEQA +H I D D  H WK+N LPLRFW+N+IKNPQFV
Sbjct: 1940 ILST---SRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFV 1996

Query: 1759 FDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADI 1818
            FD+      DA L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK  VERYYADI
Sbjct: 1997 FDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADI 2056

Query: 1819 AKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQR 1878
             +    SDQ+MN+ LAE S  ++ +     AL+E+Y Y++KY +++I ALE+D  A++ +
Sbjct: 2057 RQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQ 2116

Query: 1879 LAYKVEQLINAM 1890
            L Y+++Q+  A+
Sbjct: 2117 LGYRLQQIAAAV 2128



 Score =  275 bits (702), Expect = 4e-73
 Identities = 218/745 (29%), Positives = 345/745 (46%), Gaps = 89/745 (11%)

Query: 25  WVLLA---PPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQV 81
           WVL     PP A  P  +      RD T         +G +Y+GA N +++L+  L ++ 
Sbjct: 16  WVLTLQPLPPTAFTPNGTYLQHLARDPT---------SGTLYLGATNFLFQLSPGLQLEA 66

Query: 82  AHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLR 141
              TGP  D++ C PP++   C +    TNN N+LL++  S   L+ CGS++QGVC+  R
Sbjct: 67  TVSTGPVLDSRDCLPPVMPDECPQAQP-TNNPNQLLLV--SPGALVVCGSVHQGVCEQRR 123

Query: 142 LDDLF-ILVEPSHKKE-HYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVD--GKQDYFPT 197
           L  L  +L+ P    +  Y+++ +   +  G++ +    +  LF+G      G     P 
Sbjct: 124 LGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPP 183

Query: 198 LSSRKL-PRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFL 256
           +++R L P DP+  A   YE          K+    L+  SH    ++  FA G   YFL
Sbjct: 184 ITTRALWPPDPQ--AAFSYE-------ETAKLAVGRLSEYSHH---FVSAFARGASAYFL 231

Query: 257 TVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLA 316
            ++ +         A    + + + R+C  D  ++SYV LP  C   G  Y L+QAA +A
Sbjct: 232 FLRRDL-------QAQSRAFRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQAAAVA 282

Query: 317 KPGDSLAQAFNITSQDDVLFAIFSKGQKQ-YHHPPDD-------SALCAFPIRAINLQIK 368
              +         +  +VLFA FS         PP         SALCAFP+  ++    
Sbjct: 283 TSRE--------VAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLAN 334

Query: 369 ERLQSCYQGEGNLE-------LNWLLGKDVQCTKAPVPIDDNF-CGLDIN-QPLGGSTPV 419
               +CY  EG  E       + + +  D  C + PV   D + CG D    P+    P+
Sbjct: 335 RTRDACYTREGRAEDGTEVAYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMASRVPL 392

Query: 420 EGLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDG 479
           E   +      ++T+VA  + +G+++ F+G   G+L ++   GP   G  Y   S+ + G
Sbjct: 393 EATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYL-GPGSDGHPYSTQSI-QQG 450

Query: 480 SPILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSR 539
           S + RD+ F     +LYVM++  + +VPV SC Q+  C  CL+  DP+CGWC L   CSR
Sbjct: 451 SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSR 510

Query: 540 RDKCQQAWEPNRFAASISQ---CVSL-AVHPSSISVSEHSRLLSLVVSDAPDLSAG--IA 593
           R +C +   P ++  S      C+ + A+ P++IS  E +R + L V D P L  G   +
Sbjct: 511 RSECSRGQGPEQWLWSFQPELGCLQVAAMSPANIS-REETREVFLSVPDLPPLWPGESYS 569

Query: 594 CAFGNLTEVEGQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKF 653
           C FG   +    ++GS V+C SP P + PV+P   D+  + ++LR      +   T   F
Sbjct: 570 CHFGE-HQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAV--VIAKTSLSF 626

Query: 654 YNCSA------HQLCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLVPT 707
           Y+C A         C +CV+S + C+WC +++LCTH     S   G +  S   P + P 
Sbjct: 627 YDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCTH---KASCDAGPMVASHQSPLVSPD 683

Query: 708 EEILIPVGEVKPITLKARNLPQPQS 732
                      P   KA   P P +
Sbjct: 684 PPARGGPSPSPPTAPKALATPAPDT 708



 Score = 35.4 bits (80), Expect = 0.53
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 20/114 (17%)

Query: 744 QGAIHRV------PALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDL 797
           QG +HRV          +++ S+Q Q S+   D        + F   +   +++     L
Sbjct: 425 QGQLHRVYLGPGSDGHPYSTQSIQ-QGSAVSRD--------LTFDGTFEHLYVMTQSTLL 475

Query: 798 KVHLYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSSP--WLDWS 849
           KV +  CA Q   C  CL A R   CGWC    RC+    C+    P  WL WS
Sbjct: 476 KVPVASCA-QHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWL-WS 526



 Score = 35.0 bits (79), Expect = 0.70
 Identities = 48/203 (23%), Positives = 72/203 (35%), Gaps = 36/203 (17%)

Query: 655 NCSAHQLCLSCVNSAFR---CHWCKYRNLCTHDPTTCSFQEG------RINISEDCPQLV 705
           +C+ H  C SC+  A R   C WC     C+   + CS  +G             C Q+ 
Sbjct: 481 SCAQHLDCASCL--AHRDPYCGWCVLLGRCSRR-SECSRGQGPEQWLWSFQPELGCLQVA 537

Query: 706 PTEEILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQNS 765
                 I   E + + L   +LP    G+  Y C        H+ PAL    S V C + 
Sbjct: 538 AMSPANISREETREVFLSVPDLPPLWPGE-SYSCHFGE----HQSPAL-LTGSGVMCPSP 591

Query: 766 SYQYD-----GMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRE-----SCGLCL 815
                     G D  +++V+      G  +I       +  Y C A  E      C  C+
Sbjct: 592 DPSEAPVLPRGADYVSVSVELRF---GAVVIAKTS---LSFYDCVAVTELRPSAQCQACV 645

Query: 816 KADRKFECGWCSGERRCTLHQHC 838
            +  ++ C WC  +  CT    C
Sbjct: 646 SS--RWGCNWCVWQHLCTHKASC 666


>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
          Length = 522

 Score =  527 bits (1358), Expect = e-149
 Identities = 261/455 (57%), Positives = 333/455 (73%), Gaps = 9/455 (1%)

Query: 29  APPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQVAHKTGPE 88
           AP +     F TF  E  +  FNHL V + TG +Y+GA+NR+YKL+ +L + V H+TGP+
Sbjct: 31  APLSQKQRSFVTFRGEPAEG-FNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPD 89

Query: 89  EDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLFIL 148
           EDN  CYPP IVQ C+E LT TNNVNK+L+IDY ENRL+ACGSLYQG+CKLLRL+DLF L
Sbjct: 90  EDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKL 149

Query: 149 VEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKLPRDPE 208
            EP HKKEHYLS VN++G+++GVIV     D KLFI TAVDGK +YFPT+SSRKL ++ E
Sbjct: 150 GEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSE 209

Query: 209 SSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPE--TPEGV 266
           +  M  Y  H +FV+S+IKIPSDT  ++  FDI+Y+YGF+SG FVYFLT+QPE  +P G 
Sbjct: 210 ADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPG- 268

Query: 267 AINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPGDSLAQAF 326
             ++  +  YTS++VRLCK+D  F+SYV +P GC R+GVEYRLLQAAYL+K G  L +  
Sbjct: 269 --STTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTL 326

Query: 327 NITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWL 386
            +   DD+LF +FSKGQK+     D+SALC F ++ IN +IKERLQSCY+GEG L+L WL
Sbjct: 327 GVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWL 386

Query: 387 LGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSVASYVYNGYSVV 446
             KD+ C+ A + IDDNFCGLD+N PLG S  V G+ ++T  RDRMTSV +YVY  +S+ 
Sbjct: 387 KVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLA 446

Query: 447 FVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSP 481
           FVGTKSGKLKK    G P GG+  E + V  +G P
Sbjct: 447 FVGTKSGKLKKSFGTG-PQGGITQEWIGV--EGDP 478


>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
          Length = 492

 Score =  520 bits (1338), Expect = e-147
 Identities = 253/432 (58%), Positives = 323/432 (74%), Gaps = 6/432 (1%)

Query: 29  APPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQVAHKTGPE 88
           AP +     F TF  E  +  FNHL V + TG +Y+GA+NR+YKL+ +L + V H+TGP+
Sbjct: 31  APLSQKQRSFVTFRGEPAEG-FNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPD 89

Query: 89  EDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLFIL 148
           EDN  CYPP IVQ C+E LT TNNVNK+L+IDY ENRL+ACGSLYQG+CKLLRL+DLF L
Sbjct: 90  EDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKL 149

Query: 149 VEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKLPRDPE 208
            EP HKKEHYLS VN++G+++GVIV     D KLFI TAVDGK +YFPT+SSRKL ++ E
Sbjct: 150 GEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSE 209

Query: 209 SSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPE--TPEGV 266
           +  M  Y  H +FV+S+IKIPSDT  ++  FDI+Y+YGF+SG FVYFLT+QPE  +P G 
Sbjct: 210 ADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPG- 268

Query: 267 AINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPGDSLAQAF 326
             ++  +  YTS++VRLCK+D  F+SYV +P GC R+GVEYRLLQAAYL+K G  L +  
Sbjct: 269 --STTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTL 326

Query: 327 NITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWL 386
            +   DD+LF +FSKGQK+     D+SALC F ++ IN +IKERLQSCY+GEG L+L WL
Sbjct: 327 GVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWL 386

Query: 387 LGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSVASYVYNGYSVV 446
             KD+ C+ A + IDDNFCGLD+N PLG S  V G+ ++T  RDRMTSV +YVY  +S+ 
Sbjct: 387 KVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLA 446

Query: 447 FVGTKSGKLKKI 458
           FVGTKSGKLKK+
Sbjct: 447 FVGTKSGKLKKM 458


>gi|5032223 plexin C1 [Homo sapiens]
          Length = 1568

 Score =  422 bits (1084), Expect = e-117
 Identities = 323/960 (33%), Positives = 488/960 (50%), Gaps = 98/960 (10%)

Query: 956  VLSLNPIRGPESGGTMVTITGHYLGAGSSVAVYL-GNQTCEFYGRSMSEIVC-----VSP 1009
            + S+ P +    G + V +TG      S++ + L G  TC+     +S ++       S 
Sbjct: 664  IKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSL 723

Query: 1010 PSSNGLGPVPVSVSVDRAHVDSNLQFEYIDDPRVQRIEPEWSIASGHTPLTITGFNLDVI 1069
            PSS       V +  D  +  S     YI  P    I P  +  SG   +T+ G N DVI
Sbjct: 724  PSSRK-EMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVI 782

Query: 1070 QEPRIRVKFNGKESVNVCKVVNTTTLTCLAPSL-TTDYRPGLDTVERPDEFGFVFNNVQS 1128
                I  +  G  ++NV +    T    LAPSL ++  R  +    R  +    + +  +
Sbjct: 783  DNLIISHELKG--NINVSEYCVATYCGFLAPSLKSSKVRTNVTVKLRVQD---TYLDCGT 837

Query: 1129 LLIYNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGET 1188
            L    D +F  Y   + E+ +   V  QK      +  K++      G         G+ 
Sbjct: 838  LQYREDPRFTGYRVES-EVDTELEVKIQKENDNFNISKKDIEITLFHGEN-------GQL 889

Query: 1189 PCA---VTVSE--TQLLCEPPNL-------TGQHKVMVHVGGMVFSPGSVSVISD--SLL 1234
             C+   +T ++  T +LC+   +           KV V +G +       SV S    L+
Sbjct: 890  NCSFENITRNQDLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPSTWYFLI 949

Query: 1235 TLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECKEAFA 1294
             LP          +LL+IVI   +   R  +  +L+ K+ Q Q++ LES +  E ++ FA
Sbjct: 950  VLP----------VLLVIVIFAAVGVTRH-KSKELSRKQSQ-QLELLESELRKEIRDGFA 997

Query: 1295 ELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQHVEKALKL 1354
            ELQ D  ++        +P+LDY+ +A+R  FP       +   ++         ++L  
Sbjct: 998  ELQMDKLDVVDSFGT--VPFLDYKHFALRTFFPESGGFTHIFTEDMHNRDANDKNESLTA 1055

Query: 1355 FAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLSDLID 1414
               LI NK FL+T I TLE Q++FS++DR   AS +   LQ +L Y T +L+ L  DL++
Sbjct: 1056 LDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLME 1115

Query: 1415 KNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPI 1474
            +   +   PKL+LRRTESV EK+LTNW +  L  FL+E  GEP ++L   + Q++ KGP+
Sbjct: 1116 QC--SNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPV 1173

Query: 1475 DAITGEARYSLSEDKLIRQQIEYKTLILNCVN---PDNENSP---EIPVKVLNCDTITQV 1528
            D IT +A Y+L+ED L+ Q  E+ T+ LN V    P+NE++     I V VL+CDTI Q 
Sbjct: 1174 DVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNISVNVLDCDTIGQA 1233

Query: 1529 KEKILDA-VYKN-VPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMH 1586
            KEKI  A + KN  PY  +   + ++L+   G   + +L  +  +  +E    +LNT+ H
Sbjct: 1234 KEKIFQAFLSKNGSPYGLQLNEIGLELQ--MGTRQKELLDIDSSSVILEDGITKLNTIGH 1291

Query: 1587 YQVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLE 1646
            Y++S+ S + +  K                 I+ + S   Y+           +I PD E
Sbjct: 1292 YEISNGSTIKVFKK-----------------IANFTSDVEYSDD------HCHLILPDSE 1328

Query: 1647 SGVKVWHLVKNHDHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETLFSTVHRG 1706
            +   V         G +  G    K V E+YLT+LL+TK  +   ++ LF +++S  +  
Sbjct: 1329 AFQDV--------QGKRHRGKHKFK-VKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPN-- 1377

Query: 1707 SALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKGSI 1766
            S  P AIKY FDFLD QA+   I D DV H WK+N LPLRFWVN++KNPQFVFDI K   
Sbjct: 1378 SRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPH 1437

Query: 1767 TDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADIAKLPAISD 1826
             D CLSV+AQ FMD+ S +E +LGK++P+NKLLYAKDIP+YK  V+ YY  I  LP +S 
Sbjct: 1438 IDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSS 1497

Query: 1827 QDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQD---EQARRQRLAYKV 1883
             +M  +L ++S+ H  EFN   AL EIY Y+ KY +E++  LE++   E+A++Q L  KV
Sbjct: 1498 SEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKV 1557



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 94/397 (23%), Positives = 160/397 (40%), Gaps = 58/397 (14%)

Query: 319 GDSLAQAFNITSQDDVLFAIFSK--GQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQ 376
           G  L  + ++    DV   +FS   G+ Q    P  +ALC F +  I  + K        
Sbjct: 290 GRRLLLSSSLVEALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKR------- 342

Query: 377 GEGNLELNW-LLGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSV 435
                 ++W     +  C +   P        +  QP+  ST +            +TSV
Sbjct: 343 ------VSWDFKTAESHCKEGDQP--------ERVQPIASSTLIHS---------DLTSV 379

Query: 436 ASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFS-IDQRY 494
              V    +V+F+GT  G+L K+   G        E++  +K+ +P+   +    +   Y
Sbjct: 380 YGTVVMNRTVLFLGTGDGQLLKVIL-GENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIY 438

Query: 495 LYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEPNRF-- 552
           +Y+ + ++V R+ V +C ++ +C ECL++ DPHCGWC     C+ +  C  +     +  
Sbjct: 439 IYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLD 498

Query: 553 -AASISQCVSLAVHPSSISVSEHSRLLSLVVSDAPDLSAGIACAFGNLTEVEGQVSGSQV 611
            ++   +C  + +    I  S+    +++V S +P  S    C   N       V  S+ 
Sbjct: 499 ISSGAKKCPKIQI----IRSSKEKTTVTMVGSFSPRHS---KCMVKN-------VDSSRE 544

Query: 612 IC---ISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKFYNCSAHQLCLSCVNS 668
           +C     P       IP    +  + +       G   +S  F F NCS+ + C +CV +
Sbjct: 545 LCQNKSQPNRTCTCSIPTRATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLKECPACVET 604

Query: 669 AFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLV 705
              C WCK    C H  T C   +   N  E CP  V
Sbjct: 605 G--CAWCKSARRCIHPFTACDPSDYERN-QEQCPVAV 638



 Score = 40.0 bits (92), Expect = 0.022
 Identities = 22/56 (39%), Positives = 26/56 (46%), Gaps = 3/56 (5%)

Query: 807 QRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSS--PWLDWSSHNVKCSNPQI 860
           + +SC  CL A     CGWC   +RCT    C    +   WLD SS   KC   QI
Sbjct: 457 KHKSCSECLTATDP-HCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQI 511



 Score = 35.0 bits (79), Expect = 0.70
 Identities = 52/236 (22%), Positives = 85/236 (36%), Gaps = 60/236 (25%)

Query: 655 NCSAHQLCLSCVNSAF-RCHWCKYRNLCTH--DPTTCSFQEGRINIS---EDCPQLVPTE 708
           NC+ H+ C  C+ +    C WC     CT   D       E  ++IS   + CP++    
Sbjct: 454 NCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKI---- 509

Query: 709 EILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQNSSYQ 768
           +I+    E   +T+     P      R  +C++              +SS   CQN S  
Sbjct: 510 QIIRSSKEKTTVTMVGSFSP------RHSKCMVK-----------NVDSSRELCQNKSQP 552

Query: 769 -------------YDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCL 815
                        Y  + + N+   F   WN   + D     + +   C++ +E C  C+
Sbjct: 553 NRTCTCSIPTRATYKDVSVVNVMFSFGS-WN---LSD-----RFNFTNCSSLKE-CPACV 602

Query: 816 KADRKFECGWCSGERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGPPE 871
           +      C WC   RRC        PS    D+  +  +C  P   E  +  G P+
Sbjct: 603 ETG----CAWCKSARRCIHPFTACDPS----DYERNQEQC--PVAVEKTSGGGRPK 648


>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
          Length = 1390

 Score =  149 bits (375), Expect = 3e-35
 Identities = 134/531 (25%), Positives = 249/531 (46%), Gaps = 90/531 (16%)

Query: 62  VYVGAINRVYKLTGNLTIQVA-HKTGPEEDNKSCYPPLIVQPCSEVLTLT-----NNVNK 115
           +++GA N +Y L      +VA +KTGP  ++  C+P    Q CS    L+     +N+N 
Sbjct: 62  IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP---CQDCSSKANLSGGVWKDNINM 118

Query: 116 LLIID-YSENRLLACGSLYQGVCKL------------LRLDDLFI--LVEPSHKKEHYLS 160
            L++D Y +++L++CGS+ +G C+               +  +F   + EPS   +  +S
Sbjct: 119 ALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVS 178

Query: 161 SVNKTGTMYGVIVRSEGEDG--KLFIGTAVDGKQDYFP-----TLSSRKLPRDPESSAML 213
           ++       G  V S  +D     F+G  ++    YFP     ++S R+L    +    L
Sbjct: 179 AL-------GAKVLSSVKDRFINFFVGNTINSS--YFPDHPLHSISVRRLKETKDGFMFL 229

Query: 214 DYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPETPEGVAINSAGD 273
             + + D +                + I Y++ F S  F+YFLTVQ ET +         
Sbjct: 230 TDQSYIDVLPEFR----------DSYPIKYVHAFESNNFIYFLTVQRETLDA-------Q 272

Query: 274 LFYTSRIVRLCKDDPKFHSYVSLPFGC----------TRAGVEYRLLQAAYLAKPGDSLA 323
            F+T RI+R C  +   HSY+ +P  C          T+  V + +LQAAY++KPG  LA
Sbjct: 273 TFHT-RIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEV-FNILQAAYVSKPGAQLA 330

Query: 324 QAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLE- 382
           +    +  DD+LF +F++ +     P D SA+CAFPI+ +N    + +      + N+  
Sbjct: 331 RQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIV-----NKNNVRC 385

Query: 383 LNWLLGKDVQ-CTKAPVPIDDNFCGLDINQ-PLGGSTPVEGLTLY--TTSRDRMTSVASY 438
           L    G + + C    +  + + C    ++     +T ++ + L+    S   +TS++++
Sbjct: 386 LQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTF 445

Query: 439 VYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRD--MAFSIDQR-YL 495
           +    ++  +GT  G+  ++        G     V+ L D  P+  +  +  +++Q  Y 
Sbjct: 446 IKGDLTIANLGTSEGRFMQVVVS---RSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYT 502

Query: 496 YVMSERQVTRVPVE--SCEQYTTCGECLSSGD-PHCGWCALHNMCSRRDKC 543
            V++ +++T++P+    C  + +C +CLS+     CGWC  H+ C R ++C
Sbjct: 503 LVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWC--HDKCVRSEEC 551



 Score =  124 bits (310), Expect = 1e-27
 Identities = 110/405 (27%), Positives = 184/405 (45%), Gaps = 38/405 (9%)

Query: 809  ESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSG 868
            +SC  CL A    +CGWC    +C   + C S +     W+    +   P I ++   S 
Sbjct: 524  QSCSQCLSAPPFVQCGWCHD--KCVRSEECLSGT-----WTQ---QICLPAIYKVFPNSA 573

Query: 869  PPEGGTRVTIHGVNLGL----DFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVG 924
            P EGGTR+TI G + G      F      V +    CT    E  +   + C +G A+  
Sbjct: 574  PLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTM-NTLKCTVGPAMNK 632

Query: 925  TTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSS 984
              +  + +  G    ++ T     +++V+P + S++P  GP +GGT++T+TG+YL +G+S
Sbjct: 633  HFNMSIIISNGHGTTQYST-----FSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNS 687

Query: 985  VAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPVSVSVDRAHVDSNLQFEYIDDPRVQ 1044
              + +G +TC     S S + C +P  +       V + +D A+ ++++ F Y +DP V 
Sbjct: 688  RHISIGGKTCTLKSVSNSILECYTPAQTIST-EFAVKLKIDLANRETSI-FSYREDPIVY 745

Query: 1045 RIEPEWSIASGHTPLTITGFNLDVIQEPR--IRVKFNGKESVNVCK-VVNTTTLTCLAPS 1101
             I P  S  SG + +T  G NL+ +  PR  I V   G+     C+   N+  + C  PS
Sbjct: 746  EIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPS 805

Query: 1102 LTTDYRPGLDTVERPDEFGFVFNNVQSLLIYNDTKFIYYPNPTFELLSPTGVLDQKPGSP 1161
            L    +  L    +   F F+ + + S   Y D   IY  NP F+      ++     + 
Sbjct: 806  L---QQLNLQLPLKTKAF-FMLDGILSK--YFD--LIYVHNPVFKPFEKPVMISMGNENV 857

Query: 1162 IILKGKNLCPPASGGAKLNYTVLIGETPCA-VTVSETQLLCEPPN 1205
            + +KG ++ P A  G  L     +G   C  + +    +LC  PN
Sbjct: 858  LEIKGNDIDPEAVKGEVLK----VGNKSCENIHLHSEAVLCTVPN 898


>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
          Length = 1408

 Score =  149 bits (375), Expect = 3e-35
 Identities = 134/531 (25%), Positives = 249/531 (46%), Gaps = 90/531 (16%)

Query: 62  VYVGAINRVYKLTGNLTIQVA-HKTGPEEDNKSCYPPLIVQPCSEVLTLT-----NNVNK 115
           +++GA N +Y L      +VA +KTGP  ++  C+P    Q CS    L+     +N+N 
Sbjct: 62  IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP---CQDCSSKANLSGGVWKDNINM 118

Query: 116 LLIID-YSENRLLACGSLYQGVCKL------------LRLDDLFI--LVEPSHKKEHYLS 160
            L++D Y +++L++CGS+ +G C+               +  +F   + EPS   +  +S
Sbjct: 119 ALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVS 178

Query: 161 SVNKTGTMYGVIVRSEGEDG--KLFIGTAVDGKQDYFP-----TLSSRKLPRDPESSAML 213
           ++       G  V S  +D     F+G  ++    YFP     ++S R+L    +    L
Sbjct: 179 AL-------GAKVLSSVKDRFINFFVGNTINSS--YFPDHPLHSISVRRLKETKDGFMFL 229

Query: 214 DYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPETPEGVAINSAGD 273
             + + D +                + I Y++ F S  F+YFLTVQ ET +         
Sbjct: 230 TDQSYIDVLPEFR----------DSYPIKYVHAFESNNFIYFLTVQRETLDA-------Q 272

Query: 274 LFYTSRIVRLCKDDPKFHSYVSLPFGC----------TRAGVEYRLLQAAYLAKPGDSLA 323
            F+T RI+R C  +   HSY+ +P  C          T+  V + +LQAAY++KPG  LA
Sbjct: 273 TFHT-RIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEV-FNILQAAYVSKPGAQLA 330

Query: 324 QAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLE- 382
           +    +  DD+LF +F++ +     P D SA+CAFPI+ +N    + +      + N+  
Sbjct: 331 RQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIV-----NKNNVRC 385

Query: 383 LNWLLGKDVQ-CTKAPVPIDDNFCGLDINQ-PLGGSTPVEGLTLY--TTSRDRMTSVASY 438
           L    G + + C    +  + + C    ++     +T ++ + L+    S   +TS++++
Sbjct: 386 LQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTF 445

Query: 439 VYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRD--MAFSIDQR-YL 495
           +    ++  +GT  G+  ++        G     V+ L D  P+  +  +  +++Q  Y 
Sbjct: 446 IKGDLTIANLGTSEGRFMQVVVS---RSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYT 502

Query: 496 YVMSERQVTRVPVE--SCEQYTTCGECLSSGD-PHCGWCALHNMCSRRDKC 543
            V++ +++T++P+    C  + +C +CLS+     CGWC  H+ C R ++C
Sbjct: 503 LVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWC--HDKCVRSEEC 551



 Score =  114 bits (286), Expect = 7e-25
 Identities = 111/423 (26%), Positives = 185/423 (43%), Gaps = 56/423 (13%)

Query: 809  ESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSG 868
            +SC  CL A    +CGWC    +C   + C S +     W+    +   P I ++   S 
Sbjct: 524  QSCSQCLSAPPFVQCGWCHD--KCVRSEECLSGT-----WTQ---QICLPAIYKVFPNSA 573

Query: 869  PPEGGTRVTIHGVNLGL----DFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVG 924
            P EGGTR+TI G + G      F      V +    CT    E  +   + C +G A+  
Sbjct: 574  PLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTM-NTLKCTVGPAMNK 632

Query: 925  TTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSS 984
              +  + +  G    ++ T     +++V+P + S++P  GP +GGT++T+TG+YL +G+S
Sbjct: 633  HFNMSIIISNGHGTTQYST-----FSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNS 687

Query: 985  VAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPVSVSVDRAHVDSNLQFEYIDDPRVQ 1044
              + +G +TC     S S + C +P  +       V + +D A+ ++++ F Y +DP V 
Sbjct: 688  RHISIGGKTCTLKSVSNSILECYTPAQTIST-EFAVKLKIDLANRETSI-FSYREDPIVY 745

Query: 1045 RIEPEWS------------------IASGHTPLTITGFNLDVIQEPR--IRVKFNGKESV 1084
             I P  S                   ASG + +T  G NL+ +  PR  I V   G+   
Sbjct: 746  EIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGRNFT 805

Query: 1085 NVCK-VVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQSLLIYNDTKFIYYPNP 1143
              C+   N+  + C  PSL    +  L    +   F F+ + + S   Y D   IY  NP
Sbjct: 806  VACQHRSNSEIICCTTPSL---QQLNLQLPLKTKAF-FMLDGILSK--YFD--LIYVHNP 857

Query: 1144 TFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGETPCA-VTVSETQLLCE 1202
             F+      ++     + + +KG ++ P A  G  L     +G   C  + +    +LC 
Sbjct: 858  VFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLK----VGNKSCENIHLHSEAVLCT 913

Query: 1203 PPN 1205
             PN
Sbjct: 914  VPN 916


>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
           sapiens]
          Length = 1400

 Score =  122 bits (306), Expect = 3e-27
 Identities = 138/566 (24%), Positives = 228/566 (40%), Gaps = 96/566 (16%)

Query: 61  AVYVGAINRVYKLTGNLTIQVAHKTGPEEDN-----KSCYPPLIVQPCSEVLTLTNNVNK 115
           AV+V   NR++ L  +L    +  TGP  D       +C P     P        +   K
Sbjct: 69  AVFVAIRNRLHVLGPDLKSVQSLATGPAGDPGCQTCAACGPGPHGPP-------GDTDTK 121

Query: 116 LLIIDYSENRLLACGSLYQGVCKLLRLDDL---------FILVEPSHKKEHYLSSVNKTG 166
           +L++D +   L++CGS  QG C L  L+             L    H +         + 
Sbjct: 122 VLVLDPALPALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDCPDCVASP 181

Query: 167 TMYGVIVRSEGEDGKLFIGTAVDGK--QDYFP-TLSSRKLPRDPESSAMLDYELHSDFVS 223
               V V  +G+    ++ +++D      + P ++S R+L  D            S F  
Sbjct: 182 LGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADA-----------SGFAP 230

Query: 224 SLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRL 283
             + +      LVS + I Y++ F +G FVYFLTVQP      ++       +T R+ RL
Sbjct: 231 GFVALSVLPKHLVS-YSIEYVHSFHTGAFVYFLTVQP-----ASVTDDPSALHT-RLARL 283

Query: 284 CKDDPKFHSYVSLPFGCTRA-----------GVEYRLLQAAYLAKPGDSLAQAFNITSQD 332
              +P+   Y  L   C  A           G  Y +L+ A+ A  G  LA   +I    
Sbjct: 284 SATEPELGDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQ 343

Query: 333 DVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELN-------- 384
           +VLF +F  G+        +S +CAFPI  ++  I E ++ C +   +  L         
Sbjct: 344 EVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDEGVERCCESPVHPGLRRGLDFFQS 403

Query: 385 ----------WLLGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTS 434
                       L  +  C   P+ +  +F  +D+   L G  PV+   LY T  D +T 
Sbjct: 404 PSFCPNPPGLEALSPNTSCRHFPLLVSSSFSRVDLFNGLLG--PVQVTALYVTRLDNVT- 460

Query: 435 VASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQRY 494
                     V  +GT  G++ ++      +  +     S+   G P+ RD++   D  +
Sbjct: 461 ----------VAHMGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVSRLGD--H 508

Query: 495 LYVMSERQVTRVPVE--SCEQYTTCGECLSSGD-PHCGWCALHNMCSRRDKCQQAWEPNR 551
           L   S  QV +VP++   C  + TCG CL +     CGWC   NMC ++ +C  +W+ + 
Sbjct: 509 LLFASGDQVFQVPIQGPGCRHFLTCGRCLRAWHFMGCGWCG--NMCGQQKECPGSWQQDH 566

Query: 552 FAASISQCVSLAVHPSSISVSEHSRL 577
               +++      HP S  +   +RL
Sbjct: 567 CPPKLTE-----FHPHSGPLRGSTRL 587



 Score =  110 bits (276), Expect = 1e-23
 Identities = 87/278 (31%), Positives = 128/278 (46%), Gaps = 37/278 (13%)

Query: 810  SCGLCLKADRKFECGWCSGERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGP 869
            +CG CL+A     CGWC     C   + C  P S    W   +     P++TE    SGP
Sbjct: 532  TCGRCLRAWHFMGCGWCGN--MCGQQKEC--PGS----WQQDHCP---PKLTEFHPHSGP 580

Query: 870  PEGGTRVTIHGVNLGLDFS----EIAHHVQVAGVPCTPLPGEYI---------IAEQIVC 916
              G TR+T+ G N  L  S    E  H V V   PC PLP +             E+  C
Sbjct: 581  LRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFEC 640

Query: 917  EM---GHALVGTTSGPVRLCIGECKP--EFM---TKSHQQYTFVNPSVLSLNPIRGPESG 968
            E+   G   VG T+  V L +    P   F    T   + ++F+ P ++++ P+ GP +G
Sbjct: 641  ELEPLGTQAVGPTN--VSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAG 698

Query: 969  GTMVTITGHYLGAGSSVAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPVSVSVDRAH 1028
            GT +T+ G  L  G+S AV +    C     S  +++C +PP +  +  VP+S+ V  A 
Sbjct: 699  GTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGAT-VASVPLSLQVGGAQ 757

Query: 1029 VDSNLQFEYIDDPRVQRIEPEWSIASGHTPLTITGFNL 1066
            V  +  F+Y +DP V  I P     + H  +TI G +L
Sbjct: 758  VPGSWTFQYREDPVVLSISPNCGYINSH--ITICGQHL 793


>gi|39777610 semaphorin 4B precursor [Homo sapiens]
          Length = 837

 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 124/569 (21%), Positives = 225/569 (39%), Gaps = 104/569 (18%)

Query: 18  VVLLSVVWVLLAPPA---AGMPQFST-FHSENRDW---------TFNHLTVHQGTGAVYV 64
           ++LL ++ +LL PP    A  P+ S    SE R +          +  L + +    +YV
Sbjct: 25  LLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYV 84

Query: 65  GAINRVYKLTGNLTIQVAHKT-----GPEEDNKSCYPPLIVQPCS----EVLTLTNNVNK 115
           GA   ++ L+ NL+     +      G + + K        Q CS    +      N  K
Sbjct: 85  GAREALFALSSNLSFLPGGEYQELLWGADAEKK--------QQCSFKGKDPQRDCQNYIK 136

Query: 116 LLIIDYSENRLLACGSL-YQGVCKLLRLDDLFILVEPSHKKEHYLSSVNKTGTMYGVIVR 174
           +L+   S + L  CG+  +  +C  + +++  +  +   +K + L    K    +    +
Sbjct: 137 ILL-PLSGSHLFTCGTAAFSPMCTYINMENFTLARD---EKGNVLLEDGKGRCPFDPNFK 192

Query: 175 SEG--EDGKLFIGTAVDGKQDYFPTLSSRKLPRDPESSAMLDYELHSDFVSSLIKIPSDT 232
           S     DG+L+ GT V   Q   P +S  +  R  ++ + L++     FV+S   IP   
Sbjct: 193 STALVVDGELYTGT-VSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAY-IPESL 250

Query: 233 LALVSHFDIFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDP---- 288
            +L    D  Y +   +G    F                 +    SRI R+CK D     
Sbjct: 251 GSLQGDDDKIYFFFSETGQEFEFF----------------ENTIVSRIARICKGDEGGER 294

Query: 289 ----KFHSYVSLPFGCTRA--GVEYRLLQAAYLAKPGDSLAQAFNITSQDDVLFAIFSKG 342
               ++ S++     C+R   G  + +LQ  +   P            +D + + +F+  
Sbjct: 295 VLQQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQ-------DWRDTLFYGVFTS- 346

Query: 343 QKQYHH-PPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELN--WLLGKDVQCTKAPVP 399
             Q+H    + SA+C F ++ +     +R+ S    E N E    + +   V   +    
Sbjct: 347 --QWHRGTTEGSAVCVFTMKDV-----QRVFSGLYKEVNRETQQWYTVTHPVPTPRPGAC 399

Query: 400 IDDNFCGLDINQPL----------------GGSTPVEGLTLYTTSRDRMTSVASY--VYN 441
           I ++     IN  L                 G      L L   +R +  +V     +++
Sbjct: 400 ITNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHH 459

Query: 442 GYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQRYLYVMSER 501
            Y V+F+GT  G+L K  + GP    +  E + +   G P+ +++     +  LY  S  
Sbjct: 460 TYDVLFLGTGDGRLHKAVSVGPRVHII--EELQIFSSGQPV-QNLLLDTHRGLLYAASHS 516

Query: 502 QVTRVPVESCEQYTTCGECLSSGDPHCGW 530
            V +VP+ +C  Y +CG+CL + DP+C W
Sbjct: 517 GVVQVPMANCSLYRSCGDCLLARDPYCAW 545


>gi|39777608 semaphorin 4B precursor [Homo sapiens]
          Length = 837

 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 124/569 (21%), Positives = 225/569 (39%), Gaps = 104/569 (18%)

Query: 18  VVLLSVVWVLLAPPA---AGMPQFST-FHSENRDW---------TFNHLTVHQGTGAVYV 64
           ++LL ++ +LL PP    A  P+ S    SE R +          +  L + +    +YV
Sbjct: 25  LLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYV 84

Query: 65  GAINRVYKLTGNLTIQVAHKT-----GPEEDNKSCYPPLIVQPCS----EVLTLTNNVNK 115
           GA   ++ L+ NL+     +      G + + K        Q CS    +      N  K
Sbjct: 85  GAREALFALSSNLSFLPGGEYQELLWGADAEKK--------QQCSFKGKDPQRDCQNYIK 136

Query: 116 LLIIDYSENRLLACGSL-YQGVCKLLRLDDLFILVEPSHKKEHYLSSVNKTGTMYGVIVR 174
           +L+   S + L  CG+  +  +C  + +++  +  +   +K + L    K    +    +
Sbjct: 137 ILL-PLSGSHLFTCGTAAFSPMCTYINMENFTLARD---EKGNVLLEDGKGRCPFDPNFK 192

Query: 175 SEG--EDGKLFIGTAVDGKQDYFPTLSSRKLPRDPESSAMLDYELHSDFVSSLIKIPSDT 232
           S     DG+L+ GT V   Q   P +S  +  R  ++ + L++     FV+S   IP   
Sbjct: 193 STALVVDGELYTGT-VSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAY-IPESL 250

Query: 233 LALVSHFDIFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDP---- 288
            +L    D  Y +   +G    F                 +    SRI R+CK D     
Sbjct: 251 GSLQGDDDKIYFFFSETGQEFEFF----------------ENTIVSRIARICKGDEGGER 294

Query: 289 ----KFHSYVSLPFGCTRA--GVEYRLLQAAYLAKPGDSLAQAFNITSQDDVLFAIFSKG 342
               ++ S++     C+R   G  + +LQ  +   P            +D + + +F+  
Sbjct: 295 VLQQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQ-------DWRDTLFYGVFTS- 346

Query: 343 QKQYHH-PPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELN--WLLGKDVQCTKAPVP 399
             Q+H    + SA+C F ++ +     +R+ S    E N E    + +   V   +    
Sbjct: 347 --QWHRGTTEGSAVCVFTMKDV-----QRVFSGLYKEVNRETQQWYTVTHPVPTPRPGAC 399

Query: 400 IDDNFCGLDINQPL----------------GGSTPVEGLTLYTTSRDRMTSVASY--VYN 441
           I ++     IN  L                 G      L L   +R +  +V     +++
Sbjct: 400 ITNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHH 459

Query: 442 GYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQRYLYVMSER 501
            Y V+F+GT  G+L K  + GP    +  E + +   G P+ +++     +  LY  S  
Sbjct: 460 TYDVLFLGTGDGRLHKAVSVGPRVHII--EELQIFSSGQPV-QNLLLDTHRGLLYAASHS 516

Query: 502 QVTRVPVESCEQYTTCGECLSSGDPHCGW 530
            V +VP+ +C  Y +CG+CL + DP+C W
Sbjct: 517 GVVQVPMANCSLYRSCGDCLLARDPYCAW 545


>gi|126116589 fibrocystin L [Homo sapiens]
          Length = 4243

 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 99/411 (24%), Positives = 164/411 (39%), Gaps = 75/411 (18%)

Query: 858  PQITEILTVSGPPEGGTRVTIHGVNLGLDFS-EIAHHVQVAGVPCTPLPGEYIIAEQIVC 916
            P +  I    G  E GT +TI    +G  FS   A  V V  V C+ L    +  +++ C
Sbjct: 1067 PLVLAISPSQGSYEEGTILTI----VGSGFSPSSAVTVSVGPVGCSLLS---VDEKELKC 1119

Query: 917  EM-----GHALVGTTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLS-LNPIRGPESGGT 970
            ++     GHA V  +   V L              +++ FV  S +S + P  G  +GGT
Sbjct: 1120 QILNGSAGHAPVAVSMADVGLA--------QNVGGEEFYFVYQSQISHIWPDSGSIAGGT 1171

Query: 971  MVTITGHYLGAGSSVAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPVSVSVDRAHVD 1030
            ++T++G      S V V  GN+TC      ++ I C +P  + G   + V+ +  +A   
Sbjct: 1172 LLTLSGFGFNENSKVLV--GNETCNVIEGDLNRITCRTPKKTEGTVDISVTTNGFQATAR 1229

Query: 1031 SNLQFEYIDDPRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNGKESVNVCKVV 1090
                +  +  P +    P+     G   LTI G+N        + V   GK     C+++
Sbjct: 1230 DAFSYNCLQTPIITDFSPKVRTILGEVNLTIKGYNFGNELTQNMAVYVGGK----TCQIL 1285

Query: 1091 --NTTTLTCLAPSLTTDYRPGL-DTVERPDEFGFVF--NNVQSLLIYNDTKFIYYPNPTF 1145
              N T + CL P L+    PG  D       +GF    + + S + Y             
Sbjct: 1286 HWNFTDIRCLLPKLS----PGKHDIYVEVRNWGFASTRDKLNSSIQY------------- 1328

Query: 1146 ELLSPTGVLDQK----PGSPIILKGKNLCP-PASGGAKLNYTVLIGETPCAVTVSETQLL 1200
             +L  T +  Q+     G+ I ++G      PA        TVL+G  PC VT S   ++
Sbjct: 1329 -VLEVTSMFPQRGSLFGGTEITIRGFGFSTIPAEN------TVLLGSIPCNVTSSSENVI 1381

Query: 1201 CEPPNLTGQHKVMVHVGGMVF---SPGSVSVISDSLLTLPAIVSIAAGGSL 1248
                      K ++H  G +F   + G  SV        P +++++ G ++
Sbjct: 1382 ----------KCILHSTGNIFRITNNGKDSVHGLGYAWSPPVLNVSVGDTV 1422



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 75/340 (22%), Positives = 129/340 (37%), Gaps = 44/340 (12%)

Query: 872  GGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVGTTSGPVR 931
            G  +V I G  LG    +IA  +         +    I A      +GH  V    G   
Sbjct: 1761 GSVKVLIEGEGLGTVLEDIAVFIGNQQFRAIEVNENNITALVTPLPVGHHSVSVVVGSKG 1820

Query: 932  LCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSVAVYLGN 991
            L +G              T  +P V SL+P  G   GGT + ITG+    G++  V +G+
Sbjct: 1821 LALGNL------------TVSSPPVASLSPTSGSIGGGTTLVITGNGFYPGNT-TVTIGD 1867

Query: 992  QTCEFYGRSMSEIVCVSPPSSNGLGPVPVSVSVDRAHVDSNLQFEYIDDPRVQRIEPEWS 1051
            + C+    + +E+ C +P  + G+  V + V+   A+      +   D P ++ I P   
Sbjct: 1868 EPCQIISINPNEVYCRTPAGTTGMVDVKIFVNT-IAYPPLLFTYALEDTPFLRGIIPSRG 1926

Query: 1052 IASGHTPLTITGFNLDVIQEPRIRVKFNGKESVNVCKVVNTTTLTCLAPSLTTDYRPGLD 1111
                   +T + F  ++++   I V  N  +  NV  + N + + C+             
Sbjct: 1927 PPGTEIEITGSNFGFEILE---ISVMINNIQ-CNV-TMANDSVVQCIV------------ 1969

Query: 1112 TVERPDEFGFVFNNVQSLLIYNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCP 1171
                 D  G  F     +++++ TK        FE   P  + +  P       G+ +  
Sbjct: 1970 ----GDHAGGTF----PVMMHHKTKGSAMSTVVFEY--PLNIQNINPSQGSFGGGQTMTV 2019

Query: 1172 PASGGAKLNYTVLIGETPCAV---TVSETQLLCEPPNLTG 1208
              +G    N  +L+  + CA+       T LLCE P+  G
Sbjct: 2020 TGTGFNPQNSIILVCGSECAIDRLRSDYTTLLCEIPSNNG 2059



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 64/259 (24%), Positives = 104/259 (40%), Gaps = 34/259 (13%)

Query: 858  PQITEILTVSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCE 917
            P +  I+   GPP  GT + I G N G +  EI+  V +  + C        + +   C 
Sbjct: 1916 PFLRGIIPSRGPP--GTEIEITGSNFGFEILEIS--VMINNIQCNVTMANDSVVQ---CI 1968

Query: 918  MGHALVGTTSGPVRLCIGECKPEFMTKSHQQYTFVNP---SVLSLNPIRGPESGGTMVTI 974
            +G    GT   PV +          TK     T V     ++ ++NP +G   GG  +T+
Sbjct: 1969 VGDHAGGTF--PVMM-------HHKTKGSAMSTVVFEYPLNIQNINPSQGSFGGGQTMTV 2019

Query: 975  TGHYLGAGSSVAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLG---PVPVSVSVDRAHVDS 1031
            TG      +S+ +  G++      RS    +    PS+NG G      VSV   +    S
Sbjct: 2020 TGTGFNPQNSIILVCGSECAIDRLRSDYTTLLCEIPSNNGTGAEQACEVSVVNGKDLSQS 2079

Query: 1032 NLQFEYIDD--PRVQRIEPEWSIASGHTPLTITGFNLD--------VIQEPRIRVKFNGK 1081
               F Y     P +  + P+    +G T LT+ G             I E +  V+++ K
Sbjct: 2080 MTPFTYAVSLTPLITAVSPKRGSTAGGTRLTVVGSGFSENMEDVHITIAEAKCDVEYSNK 2139

Query: 1082 ESVNVCKVVNTTTLTCLAP 1100
              + +C + +  TL+  AP
Sbjct: 2140 THI-IC-MTDAHTLSGWAP 2156



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 66/275 (24%), Positives = 107/275 (38%), Gaps = 33/275 (12%)

Query: 954  PSVLSLNPIRGPESGGTMVTITGHYLGAGSS-VAVYLGNQTCEFYGRSMSEIVCVSPPSS 1012
            P++  + P  G  +G T VTI G      S+ V V +G+  C+    + + I C + P++
Sbjct: 1659 PNIDLVLPNAGSTTGMTSVTIKGSGFAVSSAGVKVLMGHFPCKVLSVNYTAIECETSPAA 1718

Query: 1013 NGLGPVPVSVSVDRAHVDSNLQFEYIDD--PRVQRIEPEWSIASGHTPLTITGFNLDVIQ 1070
              L  V + +    A    N  F Y++   P +  + P   I  G   + I G  L  + 
Sbjct: 1719 QQLVDVDLLIHGVPAQCQGNCTFSYLESITPYITGVFPNSVI--GSVKVLIEGEGLGTVL 1776

Query: 1071 EPRIRVKFNGKESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQSLL 1130
            E  I V F G +     + VN   +T L   L   +                     S+ 
Sbjct: 1777 ED-IAV-FIGNQQFRAIE-VNENNITALVTPLPVGH--------------------HSVS 1813

Query: 1131 IYNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGETPC 1190
            +   +K +   N T   +S   V    P S  I  G  L    +G    N TV IG+ PC
Sbjct: 1814 VVVGSKGLALGNLT---VSSPPVASLSPTSGSIGGGTTLVITGNGFYPGNTTVTIGDEPC 1870

Query: 1191 -AVTVSETQLLCE-PPNLTGQHKVMVHVGGMVFSP 1223
              ++++  ++ C  P   TG   V + V  + + P
Sbjct: 1871 QIISINPNEVYCRTPAGTTGMVDVKIFVNTIAYPP 1905



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 82/375 (21%), Positives = 131/375 (34%), Gaps = 42/375 (11%)

Query: 852  NVKCSNPQITEILTVSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIA 911
            N+  S+P +  +   SG   GGT + I     G  F      V +   PC  +    I  
Sbjct: 1825 NLTVSSPPVASLSPTSGSIGGGTTLVI----TGNGFYPGNTTVTIGDEPCQIIS---INP 1877

Query: 912  EQIVCEMGHALVGTTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTM 971
             ++ C       G     + +      P   T + +      P +  + P RGP   GT 
Sbjct: 1878 NEVYCRTPAGTTGMVDVKIFVNTIAYPPLLFTYALED----TPFLRGIIPSRGPP--GTE 1931

Query: 972  VTITGHYLGAG-SSVAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPVSVSVDRAHVD 1030
            + ITG   G     ++V + N  C     + S + C+    + G  PV +     +    
Sbjct: 1932 IEITGSNFGFEILEISVMINNIQCNVTMANDSVVQCIVGDHAGGTFPVMMHHKT-KGSAM 1990

Query: 1031 SNLQFEYIDDPRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNGKESVNVCKVV 1090
            S + FEY     +Q I P      G   +T+TG              FN + S     ++
Sbjct: 1991 STVVFEY--PLNIQNINPSQGSFGGGQTMTVTG------------TGFNPQNS-----II 2031

Query: 1091 NTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQSLLIYNDTKFIYYPNPTFELLSP 1150
                  C    L +DY   L   E P   G        + + N         P    +S 
Sbjct: 2032 LVCGSECAIDRLRSDYTTLL--CEIPSNNGTGAEQACEVSVVNGKDLSQSMTPFTYAVSL 2089

Query: 1151 TGVLDQ-KPGSPIILKGKNLCPPASGGAK--LNYTVLIGETPCAVTVS-ETQLLC--EPP 1204
            T ++    P       G  L    SG ++   +  + I E  C V  S +T ++C  +  
Sbjct: 2090 TPLITAVSPKRGSTAGGTRLTVVGSGFSENMEDVHITIAEAKCDVEYSNKTHIICMTDAH 2149

Query: 1205 NLTGQHKVMVHVGGM 1219
             L+G   V VH+ G+
Sbjct: 2150 TLSGWAPVCVHIRGV 2164



 Score = 39.3 bits (90), Expect = 0.037
 Identities = 73/306 (23%), Positives = 116/306 (37%), Gaps = 73/306 (23%)

Query: 858  PQITEILTVSGPPEGGTRVTIHG--------VNLGLDFSEIAHHVQV----AGVPCTPLP 905
            P++TEI+   G   G TR+TI G         N G+D +E+ + VQ+      + C  + 
Sbjct: 31   PKVTEIIPKYGSINGATRLTIRGEGFSQANQFNYGVDNAELGNSVQLISSFQSITC-DVE 89

Query: 906  GEYIIAEQIVC------EMGHALVGTTSGPVRLCIGECKPEFMT--KSHQQYTFVNPSVL 957
             +   + QI C      E  + +  +  G        CK    +   +    +F  P++ 
Sbjct: 90   KDASHSTQITCYTRAMPEDSYTVRVSVDGVPVTENNTCKGHINSWECTFNAKSFRTPTIR 149

Query: 958  SLNPIRGPESGGTMVTITGHYLG--AGSSVA------------VYLGNQTCE-------- 995
            S+ P+ G  + GT++TI G       GS++A            VY+G   CE        
Sbjct: 150  SITPLSG--TPGTLITIQGRIFTDVYGSNIALSSNGKNVRILRVYIGGMPCELLIPQSDN 207

Query: 996  FYG-------RSMSEIVCVSPPSSNGLGPVPVSVSVDRAHVDS------------NLQFE 1036
             YG         M  +VC +  +   +G   VS  +D  +  S            N    
Sbjct: 208  LYGLKLDHPNGDMGSMVCKT--TGTFIGHHNVSFILDNDYGRSFPQKMAYFVSSLNKIAM 265

Query: 1037 YIDDPRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNGKESVNVCKVVNTT--T 1094
            +     V  I P      G T LTI+G   D    P +RV   G+     C ++N T  +
Sbjct: 266  FQTYAEVTMIFPSQGSIRGGTTLTISGRFFDQTDFP-VRVLVGGEP----CDILNVTENS 320

Query: 1095 LTCLAP 1100
            + C  P
Sbjct: 321  ICCKTP 326



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)

Query: 956  VLSLNPIRGPESGGTMVTITGHYLGAGS-SVAVYLGNQTCEFYGRSMSEIVCVSPPSSNG 1014
            V  + P +G   GGT +TI+G +       V V +G + C+    + + I C +PP  + 
Sbjct: 272  VTMIFPSQGSIRGGTTLTISGRFFDQTDFPVRVLVGGEPCDILNVTENSICCKTPPKPHI 331

Query: 1015 LGPV 1018
            L  V
Sbjct: 332  LKTV 335


>gi|21361914 semaphorin B [Homo sapiens]
          Length = 761

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 75/316 (23%), Positives = 129/316 (40%), Gaps = 50/316 (15%)

Query: 238 HFDIFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLF---YTSRIVRLCKDD------- 287
           H D  ++    S   VYF   +          S  D F   +TSR+ R+CK+D       
Sbjct: 228 HHDASFVAAIPSTQVVYFFFEETA--------SEFDFFERLHTSRVARVCKNDVGGEKLL 279

Query: 288 -PKFHSYVSLPFGCTRAG-VEYRLLQAAYLAKPGDSLAQAFNITSQDDVLFAIFSKGQKQ 345
             K+ +++     CT+ G + + +++ A L  P DS             ++A+F+   + 
Sbjct: 280 QKKWTTFLKAQLLCTQPGQLPFNVIRHAVLL-PADSPTAPH--------IYAVFTSQWQV 330

Query: 346 YHHPPDDSALCAFPIRAINLQIKERLQ---------SCYQGEGNLELNWLLGKDVQCTKA 396
                  SA+CAF +  I    K + +         + Y+G                 KA
Sbjct: 331 --GGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSCSVGPSSDKA 388

Query: 397 PVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSVASYVYNGYS--VVFVGTKSGK 454
              + D+F  L   Q +G    V+    YT    R+    +   +G+S  V+++GT +G 
Sbjct: 389 LTFMKDHF--LMDEQVVGTPLLVKSGVEYT----RLAVETAQGLDGHSHLVMYLGTTTGS 442

Query: 455 LKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQRYLYVMSERQVTRVPVESCEQY 514
           L K    G     +  E + +  D  P+ R++  +  Q  ++V     V RVP  +C  Y
Sbjct: 443 LHKAVVSGDSSAHL-VEEIQLFPDPEPV-RNLQLAPTQGAVFVGFSGGVWRVPRANCSVY 500

Query: 515 TTCGECLSSGDPHCGW 530
            +C +C+ + DPHC W
Sbjct: 501 ESCVDCVLARDPHCAW 516


>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
          Length = 1151

 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 76/321 (23%), Positives = 124/321 (38%), Gaps = 49/321 (15%)

Query: 243 YIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDD--------PKFHSYV 294
           ++  +  G F YF        E    +  G   Y SR+ R+CK+D          + +++
Sbjct: 287 FVAAYDIGLFAYFFL-----RENAVEHDCGRTVY-SRVARVCKNDVGGRFLLEDTWTTFM 340

Query: 295 SLPFGCTRAGVEYRLLQAAYLAKPGDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSA 354
                C+R G     +   Y     + L  AF++  QD +++ +F+            SA
Sbjct: 341 KARLNCSRPGE----VPFYY-----NELQSAFHLPEQD-LIYGVFTTNVNSIAA----SA 386

Query: 355 LCAFPIRAINLQIKERLQSCYQGEGNLELNWL-LGKDV---QCTKAP-VPIDDNFCGLDI 409
           +CAF + AI+    +     ++ + N    WL +   +   QC   P    ++N     +
Sbjct: 387 VCAFNLSAIS----QAFNGPFRYQENPRAAWLPIANPIPNFQCGTLPETGPNENLTERSL 442

Query: 410 NQPLG------GSTPVEGLTLYTTSRDRMTSVASYVYNG----YSVVFVGTKSGK-LKKI 458
                         PV      T    R + +   +       Y V+++GT+SG  LK +
Sbjct: 443 QDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILKAL 502

Query: 459 RADGPPHGGVQYEMVSVLKDGS-PILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTC 517
                   G   E + VL  G    LR +      R L+V     V RVP+E C  Y + 
Sbjct: 503 STASRSLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQ 562

Query: 518 GECLSSGDPHCGWCALHNMCS 538
           G CL + DP+CGW      CS
Sbjct: 563 GACLGARDPYCGWDGKQQRCS 583


>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
          Length = 1011

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 75/347 (21%), Positives = 127/347 (36%), Gaps = 76/347 (21%)

Query: 243 YIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTR 302
           +++    G +VYF   +      V  N+ G   Y SR+ R+CK+D               
Sbjct: 223 FLHAIEYGNYVYFFFREI----AVEHNNLGKAVY-SRVARICKND--------------- 262

Query: 303 AGVEYRLLQAAYLA---------KPGDSLAQAFNITSQDDVLF-----AIFSKGQKQYHH 348
            G   R+L+  + +          PGDS      + S  D++       +      Q + 
Sbjct: 263 MGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNS 322

Query: 349 PPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWLLGKD----------------VQ 392
            P  SA+CAF +  I    K R    ++ +   +  W    +                 +
Sbjct: 323 IPG-SAVCAFSMDDIEKVFKGR----FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE 377

Query: 393 CTKAPVPIDDNFCGLDINQPLGGST--PVEGLTLYTTSRDRMTSVASYV------YNGYS 444
             K  +   D       + PL  S   P+     +T +R R    A  V      Y  Y+
Sbjct: 378 AYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYT 437

Query: 445 VVFVGTKSGKLKKIRADGPPHG-----------GVQYEMVSVLKDGSPILRDMAFSIDQR 493
           V+FVG+++G + K+ A   P                +   S   +    +  +    D  
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497

Query: 494 YLYVMSERQVTRVPVESCEQYTTCGE-CLSSGDPHCGWCALHNMCSR 539
            LYV     + R+P+  CE+Y +C + C++S DP+CGW +    C R
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLS-QGSCGR 543


>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
          Length = 597

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 75/347 (21%), Positives = 127/347 (36%), Gaps = 76/347 (21%)

Query: 243 YIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTR 302
           +++    G +VYF   +      V  N+ G   Y SR+ R+CK+D               
Sbjct: 223 FLHAIEYGNYVYFFFREI----AVEHNNLGKAVY-SRVARICKND--------------- 262

Query: 303 AGVEYRLLQAAYLA---------KPGDSLAQAFNITSQDDVLF-----AIFSKGQKQYHH 348
            G   R+L+  + +          PGDS      + S  D++       +      Q + 
Sbjct: 263 MGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNS 322

Query: 349 PPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWLLGKD----------------VQ 392
            P  SA+CAF +  I    K R    ++ +   +  W    +                 +
Sbjct: 323 IPG-SAVCAFSMDDIEKVFKGR----FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE 377

Query: 393 CTKAPVPIDDNFCGLDINQPLGGST--PVEGLTLYTTSRDRMTSVASYV------YNGYS 444
             K  +   D       + PL  S   P+     +T +R R    A  V      Y  Y+
Sbjct: 378 AYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYT 437

Query: 445 VVFVGTKSGKLKKIRADGPPHG-----------GVQYEMVSVLKDGSPILRDMAFSIDQR 493
           V+FVG+++G + K+ A   P                +   S   +    +  +    D  
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497

Query: 494 YLYVMSERQVTRVPVESCEQYTTCGE-CLSSGDPHCGWCALHNMCSR 539
            LYV     + R+P+  CE+Y +C + C++S DP+CGW +    C R
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLS-QGSCGR 543


>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
          Length = 1073

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 75/347 (21%), Positives = 127/347 (36%), Gaps = 76/347 (21%)

Query: 243 YIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTR 302
           +++    G +VYF   +      V  N+ G   Y SR+ R+CK+D               
Sbjct: 223 FLHAIEYGNYVYFFFREI----AVEHNNLGKAVY-SRVARICKND--------------- 262

Query: 303 AGVEYRLLQAAYLA---------KPGDSLAQAFNITSQDDVLF-----AIFSKGQKQYHH 348
            G   R+L+  + +          PGDS      + S  D++       +      Q + 
Sbjct: 263 MGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNS 322

Query: 349 PPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWLLGKD----------------VQ 392
            P  SA+CAF +  I    K R    ++ +   +  W    +                 +
Sbjct: 323 IPG-SAVCAFSMDDIEKVFKGR----FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE 377

Query: 393 CTKAPVPIDDNFCGLDINQPLGGST--PVEGLTLYTTSRDRMTSVASYV------YNGYS 444
             K  +   D       + PL  S   P+     +T +R R    A  V      Y  Y+
Sbjct: 378 AYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYT 437

Query: 445 VVFVGTKSGKLKKIRADGPPHG-----------GVQYEMVSVLKDGSPILRDMAFSIDQR 493
           V+FVG+++G + K+ A   P                +   S   +    +  +    D  
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497

Query: 494 YLYVMSERQVTRVPVESCEQYTTCGE-CLSSGDPHCGWCALHNMCSR 539
            LYV     + R+P+  CE+Y +C + C++S DP+CGW +    C R
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLS-QGSCGR 543


>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
          Length = 1017

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 75/347 (21%), Positives = 127/347 (36%), Gaps = 76/347 (21%)

Query: 243 YIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTR 302
           +++    G +VYF   +      V  N+ G   Y SR+ R+CK+D               
Sbjct: 223 FLHAIEYGNYVYFFFREI----AVEHNNLGKAVY-SRVARICKND--------------- 262

Query: 303 AGVEYRLLQAAYLA---------KPGDSLAQAFNITSQDDVLF-----AIFSKGQKQYHH 348
            G   R+L+  + +          PGDS      + S  D++       +      Q + 
Sbjct: 263 MGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNS 322

Query: 349 PPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWLLGKD----------------VQ 392
            P  SA+CAF +  I    K R    ++ +   +  W    +                 +
Sbjct: 323 IPG-SAVCAFSMDDIEKVFKGR----FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE 377

Query: 393 CTKAPVPIDDNFCGLDINQPLGGST--PVEGLTLYTTSRDRMTSVASYV------YNGYS 444
             K  +   D       + PL  S   P+     +T +R R    A  V      Y  Y+
Sbjct: 378 AYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYT 437

Query: 445 VVFVGTKSGKLKKIRADGPPHG-----------GVQYEMVSVLKDGSPILRDMAFSIDQR 493
           V+FVG+++G + K+ A   P                +   S   +    +  +    D  
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497

Query: 494 YLYVMSERQVTRVPVESCEQYTTCGE-CLSSGDPHCGWCALHNMCSR 539
            LYV     + R+P+  CE+Y +C + C++S DP+CGW +    C R
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLS-QGSCGR 543


>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
          Length = 998

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 75/347 (21%), Positives = 127/347 (36%), Gaps = 76/347 (21%)

Query: 243 YIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTR 302
           +++    G +VYF   +      V  N+ G   Y SR+ R+CK+D               
Sbjct: 223 FLHAIEYGNYVYFFFREI----AVEHNNLGKAVY-SRVARICKND--------------- 262

Query: 303 AGVEYRLLQAAYLA---------KPGDSLAQAFNITSQDDVLF-----AIFSKGQKQYHH 348
            G   R+L+  + +          PGDS      + S  D++       +      Q + 
Sbjct: 263 MGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNS 322

Query: 349 PPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWLLGKD----------------VQ 392
            P  SA+CAF +  I    K R    ++ +   +  W    +                 +
Sbjct: 323 IPG-SAVCAFSMDDIEKVFKGR----FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE 377

Query: 393 CTKAPVPIDDNFCGLDINQPLGGST--PVEGLTLYTTSRDRMTSVASYV------YNGYS 444
             K  +   D       + PL  S   P+     +T +R R    A  V      Y  Y+
Sbjct: 378 AYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYT 437

Query: 445 VVFVGTKSGKLKKIRADGPPHG-----------GVQYEMVSVLKDGSPILRDMAFSIDQR 493
           V+FVG+++G + K+ A   P                +   S   +    +  +    D  
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497

Query: 494 YLYVMSERQVTRVPVESCEQYTTCGE-CLSSGDPHCGWCALHNMCSR 539
            LYV     + R+P+  CE+Y +C + C++S DP+CGW +    C R
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLS-QGSCGR 543


>gi|147904700 semaphorin 5A [Homo sapiens]
          Length = 1074

 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 114/546 (20%), Positives = 195/546 (35%), Gaps = 107/546 (19%)

Query: 50  FNHLTVHQGTGAVYVGAINRVYKLTGN--LTIQVAHKTGPEEDNKSCYPPLIVQPCSEVL 107
           F+ LT   G   + VGA N +++L       IQ       E   K+CY        S+  
Sbjct: 58  FSQLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACY--------SKGK 109

Query: 108 TLTNNVNKLLIIDYSENRLLACGS-LYQGVCKLLRLDDLFILVEPSHKKEH--YLSSVNK 164
           +     N + ++    +RL  CG+  +  VC    L +L  + +         Y    N 
Sbjct: 110 SKEECQNYIRVLLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNS 169

Query: 165 TGTMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKLPRDP---ESSAMLDYELHSDF 221
           T  +           G+L+  TA+D     FP        RDP    S  +L     + +
Sbjct: 170 TALLTA--------GGELYAATAMD-----FPG-------RDPAIYRSLGILPPLRTAQY 209

Query: 222 VSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIV 281
            S  +  P+     VS +DI        G F YF        E    +  G   + SR  
Sbjct: 210 NSKWLNEPN----FVSSYDI--------GNFTYFFF-----RENAVEHDCGKTVF-SRAA 251

Query: 282 RLCKDD--------PKFHSYVSLPFGCTRAG---VEYRLLQAAYLAKPGDSLAQAFNITS 330
           R+CK+D          + +++     C+R G     Y  LQ+ +                
Sbjct: 252 RVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLP------------- 298

Query: 331 QDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWLL--- 387
           + D+++ IF+            SA+C F + AI     +     ++ + N    WL    
Sbjct: 299 ELDLIYGIFTTNVNSIAA----SAVCVFNLSAI----AQAFSGPFKYQENSRSAWLPYPN 350

Query: 388 -GKDVQCTKAPVPIDDNFCGLDINQPLGGST------PVEGLTLYTTSRDRMTSVASYVY 440
                QC      +  N    ++              PV  +  +     R + VA  V 
Sbjct: 351 PNPHFQCGTVDQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVV 410

Query: 441 NGYS----VVFVGTKSGKLKKIRAD-GPPHGGVQYEMVSVLKDG--SPILRDMAFSIDQR 493
            G      ++++ T  G +KK+R            E + +  +    PI R +     Q 
Sbjct: 411 QGREALVHIIYLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPI-RSLQILHSQS 469

Query: 494 YLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEPNRFA 553
            L+V     V ++P++ C+ Y T   C+ + DP+CGW  +   C+     +++    ++ 
Sbjct: 470 VLFVGLREHVVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCT---SLEESLSMTQWE 526

Query: 554 ASISQC 559
            SIS C
Sbjct: 527 QSISAC 532


>gi|188497703 semaphorin 3F [Homo sapiens]
          Length = 785

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 9/111 (8%)

Query: 443 YSVVFVGTKSGKLKKIRA---DGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQRYLYVMS 499
           Y V+F+GT  G ++K+     D      +  E V V KD +P+ + M  S  ++ LYV S
Sbjct: 478 YEVLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVFKDPAPV-KTMTISSKRQQLYVAS 536

Query: 500 ERQVTRVPVESCEQY-TTCGECLSSGDPHCGW----CALHNMCSRRDKCQQ 545
              VT + +  C+ Y   C +C  + DP+C W    C+ +   S+R   +Q
Sbjct: 537 AVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSKRRSRRQ 587


>gi|9910362 semaphorin sem2 [Homo sapiens]
          Length = 782

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 6/93 (6%)

Query: 443 YSVVFVGTKSGKLKKI---RADGPPHGG-VQYEMVSVLKDGSPILRDMAFSIDQRYLYVM 498
           Y V+F+GT SG + K+   +A G      V  E + V K  +PI  +M  S+ ++ LYV 
Sbjct: 451 YDVIFLGTDSGSVLKVIALQAGGSAEPEEVVLEELQVFKVPTPIT-EMEISVKRQMLYVG 509

Query: 499 SERQVTRVPVESCEQY-TTCGECLSSGDPHCGW 530
           S   V ++ +  CE Y T C EC  + DP+C W
Sbjct: 510 SRLGVAQLRLHQCETYGTACAECCLARDPYCAW 542


>gi|157388902 semaphorin 4C [Homo sapiens]
          Length = 833

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 4/95 (4%)

Query: 443 YSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQRYLYVMSERQ 502
           Y+V+F+GT  G L K  + GP    V       L D  P +R +  S  ++ L+  S  Q
Sbjct: 436 YTVLFIGTGDGWLLKAVSLGP---WVHLIEELQLFDQEP-MRSLVLSQSKKLLFAGSRSQ 491

Query: 503 VTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMC 537
           + ++PV  C +Y +C +C+ + DP+C W    + C
Sbjct: 492 LVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRC 526


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,353,382
Number of Sequences: 37866
Number of extensions: 3570142
Number of successful extensions: 8178
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 7719
Number of HSP's gapped (non-prelim): 214
length of query: 1894
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1777
effective length of database: 13,817,196
effective search space: 24553157292
effective search space used: 24553157292
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.