Search of human proteins with 21361091

Search of human proteins with 21361091

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361091 ubiquitin carboxyl-terminal esterase L1 [Homo
sapiens]
         (223 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361091 ubiquitin carboxyl-terminal esterase L1 [Homo sapiens]    450   e-127
gi|5174741 ubiquitin carboxyl-terminal esterase L3 [Homo sapiens]     258   3e-69
gi|7706753 ubiquitin carboxyl-terminal hydrolase L5 [Homo sapiens]     69   4e-12
gi|4757836 BRCA1 associated protein-1 [Homo sapiens]                   59   3e-09
gi|240849353 gamma isoform of regulatory subunit B56, protein ph...    28   8.2  
gi|31083259 gamma isoform of regulatory subunit B56, protein pho...    28   8.2  
gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo s...    28   8.2  
gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo s...    28   8.2  
gi|41281453 serine/threonine kinase 2 [Homo sapiens]                   28   8.2  

>gi|21361091 ubiquitin carboxyl-terminal esterase L1 [Homo sapiens]
          Length = 223

 Score =  450 bits (1157), Expect = e-127
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHE 60
           MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHE
Sbjct: 1   MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHE 60

Query: 61  NFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSE 120
           NFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSE
Sbjct: 61  NFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSE 120

Query: 121 TEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMP 180
           TEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMP
Sbjct: 121 TEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMP 180

Query: 181 FPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA 223
           FPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA
Sbjct: 181 FPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA 223


>gi|5174741 ubiquitin carboxyl-terminal esterase L3 [Homo sapiens]
          Length = 230

 Score =  258 bits (659), Expect = 3e-69
 Identities = 123/223 (55%), Positives = 168/223 (75%), Gaps = 5/223 (2%)

Query: 5   PMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRK 64
           P+E NPE+ N+ L +LG+   W+FVDV G++ E L  VP P CA+LLLFP+T ++E FR 
Sbjct: 8   PLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRT 67

Query: 65  KQIEELK--GQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETE 122
           ++ E++K  GQ+V+  VYFMKQTI N+CGTIGLIHA+ANN+DK+ FE GS LK+FL E+ 
Sbjct: 68  EEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESV 127

Query: 123 KMSPEDRAKCFEKNEAIQAAHDAVAQEGQCR---VDDKVNFHFILFNNVDGHLYELDGRM 179
            MSPE+RA+  E  +AI+  H+  A EGQ     +D+KV+ HFI   +VDGHLYELDGR 
Sbjct: 128 SMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRK 187

Query: 180 PFPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKA 222
           PFP+NHG +S++TLL+DA +VC++F ER+  E+RF+A+AL  A
Sbjct: 188 PFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA 230


>gi|7706753 ubiquitin carboxyl-terminal hydrolase L5 [Homo sapiens]
          Length = 329

 Score = 68.6 bits (166), Expect = 4e-12
 Identities = 55/227 (24%), Positives = 103/227 (45%), Gaps = 27/227 (11%)

Query: 6   MEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKK 65
           ME +P +  +++   G  G  +  ++  LE E+   +  P   L+ LF         + +
Sbjct: 11  MESDPGVFTELIKGFGCRGA-QVEEIWSLEPENFEKLK-PVHGLIFLF---------KWQ 59

Query: 66  QIEELKGQEVSPK----VYFMKQTIGNSCGTIGLIHAVAN--NQDKLGFEDGSVLKQFLS 119
             EE  G  V       ++F KQ I N+C T  ++  + N  +QD      G  L +F  
Sbjct: 60  PGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQD---VHLGETLSEFKE 116

Query: 120 ETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVN------FHFILFNNVDGHLY 173
            ++      +      ++ I+  H++ A++     D K +      FHF+ +  V+G LY
Sbjct: 117 FSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLY 176

Query: 174 ELDGRMPFPVNHGASSEDTLLKDAAKVCREFTER-EQGEVRFSAVAL 219
           ELDG    P++ GA ++D  +     V  +  ++  +GE+RF+ +A+
Sbjct: 177 ELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAI 223


>gi|4757836 BRCA1 associated protein-1 [Homo sapiens]
          Length = 729

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 48/208 (23%), Positives = 86/208 (41%), Gaps = 22/208 (10%)

Query: 6   MEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKK 65
           +E +P +   ++   GV G  +  ++  L+ +  G    P    + LF    +  + RK 
Sbjct: 8   LESDPGLFTLLVEDFGVKGV-QVEEIYDLQSKCQG----PVYGFIFLFKWIEERRSRRKV 62

Query: 66  QI----EELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSET 121
                   +   ++   ++F  Q I NSC T  L+  + N       + G  L +    T
Sbjct: 63  STLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSS---VDLGPTLSRMKDFT 119

Query: 122 EKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVN----------FHFILFNNVDGH 171
           +  SPE +         +  AH++ A+     + +K N          FHF+ +  + G 
Sbjct: 120 KGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGR 179

Query: 172 LYELDGRMPFPVNHGASSEDTLLKDAAK 199
           L+ELDG   +P++HG   ED    D A+
Sbjct: 180 LFELDGLKVYPIDHGPWGEDEEWTDKAR 207


>gi|240849353 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform e [Homo sapiens]
          Length = 555

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 4/62 (6%)

Query: 99  VANNQDKLGFEDGSVLKQFLSE----TEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRV 154
           VA   D   FED  +L++ + +     +K   +DR     K+E  Q  H   A E  CR 
Sbjct: 487 VAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRA 546

Query: 155 DD 156
           D+
Sbjct: 547 DE 548


>gi|31083259 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform a [Homo sapiens]
          Length = 524

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 4/62 (6%)

Query: 99  VANNQDKLGFEDGSVLKQFLSE----TEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRV 154
           VA   D   FED  +L++ + +     +K   +DR     K+E  Q  H   A E  CR 
Sbjct: 456 VAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRA 515

Query: 155 DD 156
           D+
Sbjct: 516 DE 517


>gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo
           sapiens]
          Length = 462

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 2/40 (5%)

Query: 104 DKLGFEDGSVLKQ--FLSETEKMSPEDRAKCFEKNEAIQA 141
           + L  E   +LKQ  FL E  K   ++R  CF+KN+A +A
Sbjct: 356 ESLQREKAGLLKQLDFLRERNKHLRDERDICFQKNKAAKA 395


>gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo
           sapiens]
          Length = 731

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 2/40 (5%)

Query: 104 DKLGFEDGSVLKQ--FLSETEKMSPEDRAKCFEKNEAIQA 141
           + L  E   +LKQ  FL E  K   ++R  CF+KN+A +A
Sbjct: 356 ESLQREKAGLLKQLDFLRERNKHLRDERDICFQKNKAAKA 395


>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
          Length = 1235

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 18/83 (21%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 56   TAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIH-AVANNQDKLGFEDGSVL 114
            T Q + + ++ IEELK ++   +    K     +   + +   ++  N      +D   +
Sbjct: 1046 TEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKI 1105

Query: 115  KQFLSETEKMSPEDRAKCFEKNE 137
            KQF ++ EK    +R    +K+E
Sbjct: 1106 KQFAAQEEKRQKNERMAQHQKHE 1128


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,316,116
Number of Sequences: 37866
Number of extensions: 348193
Number of successful extensions: 698
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 691
Number of HSP's gapped (non-prelim): 9
length of query: 223
length of database: 18,247,518
effective HSP length: 98
effective length of query: 125
effective length of database: 14,536,650
effective search space: 1817081250
effective search space used: 1817081250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.