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Search of human proteins with 211904182
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
(631 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 1295 0.0
gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens] 951 0.0
gi|30089954 H326 [Homo sapiens] 841 0.0
gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens] 137 3e-32
gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens] 137 3e-32
gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] 122 1e-27
gi|55741849 WD repeat domain 22 [Homo sapiens] 82 1e-15
gi|17975763 myelin transcription factor 1 [Homo sapiens] 72 1e-12
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 71 3e-12
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 70 5e-12
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 70 5e-12
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 66 8e-11
gi|221219020 NYD-SP11 protein [Homo sapiens] 64 4e-10
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 64 6e-10
gi|4504487 histidine rich calcium binding protein precursor [Hom... 63 7e-10
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 63 7e-10
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 62 2e-09
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 61 3e-09
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 61 3e-09
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 61 3e-09
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 61 3e-09
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 61 3e-09
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 61 3e-09
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 61 3e-09
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 61 3e-09
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 61 3e-09
gi|28274705 family with sequence similarity 9, member A [Homo sa... 61 3e-09
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 61 3e-09
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 61 4e-09
gi|147904340 WD repeat domain 82 [Homo sapiens] 60 5e-09
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 1295 bits (3350), Expect = 0.0
Identities = 631/631 (100%), Positives = 631/631 (100%)
Query: 1 MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDG 60
MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDG
Sbjct: 1 MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDG 60
Query: 61 GFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI 120
GFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI
Sbjct: 61 GFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI 120
Query: 121 QEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETS 180
QEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETS
Sbjct: 121 QEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETS 180
Query: 181 ALPRPRWQVVTALHQRQLGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRG 240
ALPRPRWQVVTALHQRQLGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRG
Sbjct: 181 ALPRPRWQVVTALHQRQLGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRG 240
Query: 241 TRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVA 300
TRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVA
Sbjct: 241 TRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVA 300
Query: 301 ELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT 360
ELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT
Sbjct: 301 ELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT 360
Query: 361 RENDKKVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCD 420
RENDKKVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCD
Sbjct: 361 RENDKKVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCD 420
Query: 421 FPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGP 480
FPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGP
Sbjct: 421 FPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGP 480
Query: 481 RSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIW 540
RSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIW
Sbjct: 481 RSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIW 540
Query: 541 TPTAKAATELTGLKKVIKKNKWERDEDSLHHGSLFDQYMLWFLLRHVTQRGRHQDWRSGE 600
TPTAKAATELTGLKKVIKKNKWERDEDSLHHGSLFDQYMLWFLLRHVTQRGRHQDWRSGE
Sbjct: 541 TPTAKAATELTGLKKVIKKNKWERDEDSLHHGSLFDQYMLWFLLRHVTQRGRHQDWRSGE 600
Query: 601 AEFPDEESDESSSTSETSEEEVQDRVQCMPS 631
AEFPDEESDESSSTSETSEEEVQDRVQCMPS
Sbjct: 601 AEFPDEESDESSSTSETSEEEVQDRVQCMPS 631
>gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens]
Length = 600
Score = 951 bits (2458), Expect = 0.0
Identities = 481/632 (76%), Positives = 520/632 (82%), Gaps = 33/632 (5%)
Query: 1 MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDG 60
MSHQEGST GLPDL TESLFSSPEEQSG A T ASSDI++A +E S TGDG D+RDG
Sbjct: 1 MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPS---TGDGGDTRDG 57
Query: 61 GFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI 120
GF NDASTEN+++D ES+SED+ELES+ GE LF YPLVGEE
Sbjct: 58 GFLNDASTENQNTDSESSSEDVELESM---------GEGLFGYPLVGEET---------- 98
Query: 121 QEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETS 180
E EEEEEE EEE EEEEQPR P+ G NH+Q L+EDQALEEW+SSETS
Sbjct: 99 ----------EREEEEEEMEEEGEEEEQPRMCPRCGGTNHDQCLLDEDQALEEWISSETS 148
Query: 181 ALPRPRWQVVTALHQRQLGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRG 240
ALPR RWQV+TAL QRQLGS RFVYEACGAR FVQRFRLQY L H G V+T+HFNQRG
Sbjct: 149 ALPRSRWQVLTALRQRQLGSSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRG 208
Query: 241 TRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVA 300
TRLASSGDDL+VIVWDWVRQ+PVLNFESGH NV QAKF PNCGDSTLAMC DGQVRVA
Sbjct: 209 TRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHDGQVRVA 268
Query: 301 ELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT 360
ELINASY NTK VA+HRGPAH+LALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT
Sbjct: 269 ELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT 328
Query: 361 RENDKKVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCD 420
RENDKKVGLYTI++NPAN YQFAVGG DQFVRIYDQR+IDKKENNGVLKKFTPHHLV CD
Sbjct: 329 RENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKENNGVLKKFTPHHLVYCD 388
Query: 421 FPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGP 480
FPTNITCVVYSHDGTELLASYND+DIYLFNSS SDGAQY KR+KGHRNN T+K VNFYGP
Sbjct: 389 FPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKGHRNNDTIKCVNFYGP 448
Query: 481 RSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIW 540
RSEFVVSGSDCGH+FFWEKSS QIIQF++G R +NCLEPHPYLPVLA SGLD V+IW
Sbjct: 449 RSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLPVLATSGLDQHVRIW 508
Query: 541 TPTAKAATELTGLKKVIKKNKWERDEDSLHHGSLFDQYMLWFLLRHVTQRGRHQDWRSGE 600
TPTAK ATELTGLK VIKKNK ERDED+L++ FD ML F +RH+ QR WR
Sbjct: 509 TPTAKTATELTGLKDVIKKNKQERDEDNLNYTDSFDNRMLRFFVRHLLQRAHQPGWRDHG 568
Query: 601 AEFPDEES-DESSSTSETSEEEVQDRVQCMPS 631
AEFPDEE DESSSTS+TSEEE QDRVQC+PS
Sbjct: 569 AEFPDEEELDESSSTSDTSEEEGQDRVQCIPS 600
>gi|30089954 H326 [Homo sapiens]
Length = 597
Score = 841 bits (2172), Expect = 0.0
Identities = 426/632 (67%), Positives = 489/632 (77%), Gaps = 36/632 (5%)
Query: 1 MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDG 60
MS + STDG DL SL SSPEE SGA E SS I++ S+LS+++TGD DG
Sbjct: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGD-----DG 55
Query: 61 GFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI 120
G PN STE+R +D ES+ ED + +S+ED H+ ++ E+ H
Sbjct: 56 G-PNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVH------------------ 96
Query: 121 QEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETS 180
+ EEEEEE EEEEEEEQPR Q N +Q S ++++ALE+WVSSETS
Sbjct: 97 ----------DRSEEEEEE-EEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETS 145
Query: 181 ALPRPRWQVVTALHQRQLGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRG 240
ALPRPRWQ + AL +R+LGS RFVYEACGAR FVQRFRLQ+ L H GCVNT+HFNQRG
Sbjct: 146 ALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRG 205
Query: 241 TRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVA 300
T LAS DDLKV+VWDWVR++PVL+FESGH +NVFQAKFLPN GDSTLAMCARDGQVRVA
Sbjct: 206 TWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVA 265
Query: 301 ELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT 360
EL NTK VAQH+G +HKLALEPDSP FL++GEDAVVFTIDLRQDRPASK+VVT
Sbjct: 266 ELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVT 325
Query: 361 RENDKKVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCD 420
+E +KKVGLYTI VNPANT+QFAVGG+DQFVRIYDQRKID+ ENNGVLKKF PHHLVN +
Sbjct: 326 KEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSE 385
Query: 421 FPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGP 480
NITC+VYSHDGTELLASYND+DIYLFNSSHSDGAQY KR+KGHRNN TVKGVNFYGP
Sbjct: 386 SKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGP 445
Query: 481 RSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIW 540
+SEFVVSGSDCGHIF WEKSSCQIIQF++G + G +NCLEPHP+LPVLA SGLDHDVKIW
Sbjct: 446 KSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505
Query: 541 TPTAKAATELTGLKKVIKKNKWERDEDSLHHGSLFDQYMLWFLLRHVTQRGRHQDWRSGE 600
PTA+A+TELTGLK VIKKNK ERDEDSLH LFD +MLWFL+ H+ QR H+ WR
Sbjct: 506 APTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPG 565
Query: 601 AEFPDEESDESSSTSETS-EEEVQDRVQCMPS 631
D +SDES S+S+TS EEE DRVQCMPS
Sbjct: 566 VGATDADSDESPSSSDTSDEEEGPDRVQCMPS 597
>gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]
Length = 860
Score = 137 bits (345), Expect = 3e-32
Identities = 94/293 (32%), Positives = 137/293 (46%), Gaps = 32/293 (10%)
Query: 177 SETSALPRPRWQVVTALHQRQLG----SRPRFVYEACGARAFVQRFRLQYRLADHVGCVN 232
S + P W V +R LG SR R Y G R F+QR +L+ L H GCVN
Sbjct: 2 SRGGSYPHLLWDV----RKRSLGLEDPSRLRSRY--LGRREFIQRLKLEATLNVHDGCVN 55
Query: 233 TVHFNQRGTRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCA 292
T+ +N G + S DD K+++ + ++ + SGH N+F AKFLP D + C+
Sbjct: 56 TICWNDTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCS 115
Query: 293 RDGQVRVAELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDR 352
DG + + + N H G +++ P+ PY FL+ GED V D R
Sbjct: 116 GDGVIFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR--- 172
Query: 353 PASKVVVTRENDK-------KVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKE-- 403
K T+E+ K + ++ + P Y AVG D VRIYD+R + +
Sbjct: 173 --IKTSCTKEDCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATG 230
Query: 404 ------NNGVLKKFTPHHLVNCDFPTNITCVVYSHDGTELLASYNDDDIYLFN 450
G++ +F P HL N +T + YS DG E+L SY+ D IYLF+
Sbjct: 231 NYAGRGTTGMVARFIPSHLNNKS--CRVTSLCYSEDGQEILVSYSSDYIYLFD 281
Score = 94.0 bits (232), Expect = 4e-19
Identities = 40/81 (49%), Positives = 60/81 (74%), Gaps = 4/81 (4%)
Query: 463 FKGHRNNTT-VKGVNFYGPRSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEP 521
+KGHRN+ T +K NF+G + FV+SGSDCGHIF W++ + + + L+ +NCL+P
Sbjct: 713 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADNH-VVNCLQP 769
Query: 522 HPYLPVLACSGLDHDVKIWTP 542
HP+ P+LA SG+D+D+KIW+P
Sbjct: 770 HPFDPILASSGIDYDIKIWSP 790
>gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]
Length = 880
Score = 137 bits (345), Expect = 3e-32
Identities = 94/293 (32%), Positives = 137/293 (46%), Gaps = 32/293 (10%)
Query: 177 SETSALPRPRWQVVTALHQRQLG----SRPRFVYEACGARAFVQRFRLQYRLADHVGCVN 232
S + P W V +R LG SR R Y G R F+QR +L+ L H GCVN
Sbjct: 2 SRGGSYPHLLWDV----RKRSLGLEDPSRLRSRY--LGRREFIQRLKLEATLNVHDGCVN 55
Query: 233 TVHFNQRGTRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCA 292
T+ +N G + S DD K+++ + ++ + SGH N+F AKFLP D + C+
Sbjct: 56 TICWNDTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCS 115
Query: 293 RDGQVRVAELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDR 352
DG + + + N H G +++ P+ PY FL+ GED V D R
Sbjct: 116 GDGVIFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR--- 172
Query: 353 PASKVVVTRENDK-------KVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKE-- 403
K T+E+ K + ++ + P Y AVG D VRIYD+R + +
Sbjct: 173 --IKTSCTKEDCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATG 230
Query: 404 ------NNGVLKKFTPHHLVNCDFPTNITCVVYSHDGTELLASYNDDDIYLFN 450
G++ +F P HL N +T + YS DG E+L SY+ D IYLF+
Sbjct: 231 NYAGRGTTGMVARFIPSHLNNKS--CRVTSLCYSEDGQEILVSYSSDYIYLFD 281
Score = 94.0 bits (232), Expect = 4e-19
Identities = 40/81 (49%), Positives = 60/81 (74%), Gaps = 4/81 (4%)
Query: 463 FKGHRNNTT-VKGVNFYGPRSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEP 521
+KGHRN+ T +K NF+G + FV+SGSDCGHIF W++ + + + L+ +NCL+P
Sbjct: 733 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADNH-VVNCLQP 789
Query: 522 HPYLPVLACSGLDHDVKIWTP 542
HP+ P+LA SG+D+D+KIW+P
Sbjct: 790 HPFDPILASSGIDYDIKIWSP 810
>gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
Length = 676
Score = 122 bits (306), Expect = 1e-27
Identities = 89/309 (28%), Positives = 136/309 (44%), Gaps = 47/309 (15%)
Query: 214 FVQRFRLQYRLADHVGCVNTVHFNQRGTRLASSGDDLKVIVWDWVRQRPVLNFESGHTNN 273
F++R L+ L H GCVN + +N++G LAS DD IVWD + + +L+ +GHT N
Sbjct: 33 FIRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTAN 92
Query: 274 VFQAKFLPNCGDSTLAMCARDGQVRVAELINASYFNNTKCVAQHRGPAHKLALEPDSPYK 333
+F KFLP+ GD L A D +V V +L + H ++A P P
Sbjct: 93 IFSVKFLPHAGDRILITGAADSKVHVHDL---TVKETIHMFGDHTNRVKRIATAPMWPNT 149
Query: 334 FLTSGEDAVVFTIDLRQDRPASKVVV--TRENDKKVGLYTITVNPANTYQFAVGGQDQFV 391
F ++ ED ++ DLR++ S+V++ T + V +TVNP + AVG FV
Sbjct: 150 FWSAAEDGLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFV 209
Query: 392 RIYDQRKI---------------------DKKENNGVLKKFTPHHLVNC--DFPTNI--- 425
R+YD R I K +G + + HL D+ +
Sbjct: 210 RLYDIRMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVL 269
Query: 426 --TCVVYSHDGTELLASYNDDDIYLFN--------------SSHSDGAQYSKRFKGHRNN 469
T V +S +GTELL + + +YLF+ HS G Q K +N
Sbjct: 270 VATYVTFSPNGTELLVNMGGEQVYLFDLTYKQRPYTFLLPRKCHSSGVQNGKMSTNGVSN 329
Query: 470 TTVKGVNFY 478
G++ +
Sbjct: 330 GVSNGLHLH 338
Score = 87.0 bits (214), Expect = 5e-17
Identities = 45/114 (39%), Positives = 70/114 (61%), Gaps = 7/114 (6%)
Query: 440 SYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTT-VKGVNFYGPRSEFVVSGSDCGHIFFWE 498
S ++D++ L S+ Y R+ GH N TT +K NF+G ++++VSGSD G F WE
Sbjct: 510 SISEDEMVLRERSYD----YQFRYCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWE 565
Query: 499 KSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIWTPTAKAATELTG 552
K + +++ L+G E +NCL+PHP LA SG+D V++W P + + +LTG
Sbjct: 566 KETTNLVRVLQGD-ESIVNCLQPHPSYCFLATSGIDPVVRLWNPRPE-SEDLTG 617
>gi|55741849 WD repeat domain 22 [Homo sapiens]
Length = 942
Score = 82.0 bits (201), Expect = 1e-15
Identities = 88/371 (23%), Positives = 160/371 (43%), Gaps = 39/371 (10%)
Query: 189 VVTALHQRQLGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRGTR-LASSG 247
VV L QR L P + R R + L H GCVN + F+ G + L S G
Sbjct: 14 VVGFLSQRGLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGGQWLVSGG 73
Query: 248 DDLKVIVWDWV-----RQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVAEL 302
DD +V++W R +P+ + H +N+F F N G++ + D QV + ++
Sbjct: 74 DDRRVLLWHMEQAIHSRVKPI-QLKGEHHSNIFCLAF--NSGNTKVFSGGNDEQVILHDV 130
Query: 303 INASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRE 362
++ T V H + L++ P + F +S +D V D+R+ +
Sbjct: 131 ESSE----TLDVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIRESPHGEPFCLANY 186
Query: 363 NDKKVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCDFP 422
+++ NP A + V ++D RK + +L+ + N
Sbjct: 187 PS---AFHSVMFNPVEPRLLATANSKEGVGLWDIRK----PQSSLLR-----YGGNLSLQ 234
Query: 423 TNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGPRS 482
+ ++ V ++ +GT+LLA L++ HS + +G+ N+ T+K F G R
Sbjct: 235 SAMS-VRFNSNGTQLLALRRRLPPVLYDI-HSRLPVFQFDNQGYFNSCTMKSCCFAGDRD 292
Query: 483 EFVVSGSDCGHIFFWE-----------KSSCQIIQFLKGSREGTINCLEPHPYLPVLACS 531
++++SGSD +++ W + LKG R +N + +P+ ++ S
Sbjct: 293 QYILSGSDDFNLYMWRIPADPEAGGIGRVVNGAFMVLKGHR-SIVNQVRFNPHTYMICSS 351
Query: 532 GLDHDVKIWTP 542
G++ +KIW+P
Sbjct: 352 GVEKIIKIWSP 362
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 72.4 bits (176), Expect = 1e-12
Identities = 54/151 (35%), Positives = 68/151 (45%), Gaps = 41/151 (27%)
Query: 4 QEGSTDGLPDLGTESLFSSPEEQSGAV-AATEASSDIDIATSELSVTVTGDGSDSRDGGF 62
QE + + G + LF PE+ V TE S D+
Sbjct: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLC---------------------- 236
Query: 63 PNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQE 122
S E+ +S++ S + I ED E EEE E EEE++E +E
Sbjct: 237 --PQSLEDAASEESSKQKGILSHEEEDEE----------------EEEEEEEEEEDEEEE 278
Query: 123 EGGEEEEEEEEEEEEEEEEEEEEEEQPRAGP 153
E EEEEEEEEEEEEEEEEEEEEEE+ A P
Sbjct: 279 EEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309
Score = 58.9 bits (141), Expect = 1e-08
Identities = 40/111 (36%), Positives = 57/111 (51%), Gaps = 20/111 (18%)
Query: 79 SEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEE 138
S+D+ +SLED EE+ +++ +EE EEEEEEEEEEE+E
Sbjct: 232 SQDLCPQSLED----------------AASEESSKQKGILSHEEEDEEEEEEEEEEEEDE 275
Query: 139 EEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWV----SSETSALPRP 185
EEEEEEEEE+ + E+ EE++A + + +S TSA P
Sbjct: 276 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAP 326
Score = 31.2 bits (69), Expect = 3.0
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 98 ESLFHYPLVGEEETE-REEEDEEIQEEGGEEEEEEEEEEEE---EEEEEEEEEEQPRAGP 153
+ LF P EE E E +++ + E+ EE +++ EEE+EEEE+
Sbjct: 212 KGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEE 271
Query: 154 QGSGGNHEQYSLEEDQALEE 173
+ E+ EE++ EE
Sbjct: 272 EEDEEEEEEEEEEEEEEEEE 291
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 71.2 bits (173), Expect = 3e-12
Identities = 46/94 (48%), Positives = 56/94 (59%), Gaps = 12/94 (12%)
Query: 90 FEHFLMSGESLFHYPLV----GEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEE 145
F H L++ + P+ G+EE E EEEDEE +EE EEEEEEEEEEEEEEEEEEEE
Sbjct: 710 FSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769
Query: 146 EEQPRA-------GPQGSGGNHEQYSLEEDQALE 172
EE A GP+ SG + E D++ E
Sbjct: 770 EEAAAAVALGEVLGPR-SGSSSEGSERSTDRSQE 802
Score = 33.9 bits (76), Expect = 0.47
Identities = 17/40 (42%), Positives = 24/40 (60%)
Query: 134 EEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
+EEEEEEEE+EEEE+ + E+ EE++ EE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 32.0 bits (71), Expect = 1.8
Identities = 17/47 (36%), Positives = 26/47 (55%)
Query: 136 EEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETSAL 182
+EEEEEEEE+EE+ + E+ EE++ EE ++ AL
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVAL 778
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 70.5 bits (171), Expect = 5e-12
Identities = 53/161 (32%), Positives = 72/161 (44%), Gaps = 24/161 (14%)
Query: 12 PDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDGGFPNDASTENR 71
P+ +S E+ G AS + E++ G ++ G +D N
Sbjct: 140 PERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSG-SSDEQGNNT 198
Query: 72 SSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEE 131
+++E ED+E ED EE E EEDEE+ E+G EEEEEE
Sbjct: 199 ENEEEGVEEDVE----ED------------------EEVEEDAEEDEEVDEDG-EEEEEE 235
Query: 132 EEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALE 172
EEEEEEEEEEEEEE EQ + G +++ S D E
Sbjct: 236 EEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSE 276
Score = 48.5 bits (114), Expect = 2e-05
Identities = 39/123 (31%), Positives = 58/123 (47%), Gaps = 10/123 (8%)
Query: 51 TGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEE 110
T DGS+ AS ++SS +E SE+ D E +G S E
Sbjct: 148 TPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG----SDHE----TGSSGSSDEQGNNTE 199
Query: 111 TEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQA 170
E E +E+++E+ EE EE+ EE+EE +E+ EEEEE+ + E+Y +E
Sbjct: 200 NEEEGVEEDVEED--EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQ 257
Query: 171 LEE 173
EE
Sbjct: 258 KEE 260
Score = 36.6 bits (83), Expect = 0.072
Identities = 31/141 (21%), Positives = 57/141 (40%), Gaps = 9/141 (6%)
Query: 22 SPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASED 81
S + V + E SD + +S S G+ +++ + G D + + E+
Sbjct: 166 SSQSSKEEVNSEEYGSDHETGSSGSS-DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEE 224
Query: 82 IELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEE 141
++ + E+ E E EEE E E+DE Q+E G + + E + E
Sbjct: 225 VDEDGEEEEEEEEEEEEE-------EEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSES 277
Query: 142 EEEEEEQPRAGPQGSGGNHEQ 162
+ R+G G+ G+ E+
Sbjct: 278 VSFTDGSVRSG-SGTDGSDEK 297
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 70.5 bits (171), Expect = 5e-12
Identities = 53/161 (32%), Positives = 72/161 (44%), Gaps = 24/161 (14%)
Query: 12 PDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDGGFPNDASTENR 71
P+ +S E+ G AS + E++ G ++ G +D N
Sbjct: 140 PERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSG-SSDEQGNNT 198
Query: 72 SSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEE 131
+++E ED+E ED EE E EEDEE+ E+G EEEEEE
Sbjct: 199 ENEEEGVEEDVE----ED------------------EEVEEDAEEDEEVDEDG-EEEEEE 235
Query: 132 EEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALE 172
EEEEEEEEEEEEEE EQ + G +++ S D E
Sbjct: 236 EEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSE 276
Score = 48.5 bits (114), Expect = 2e-05
Identities = 39/123 (31%), Positives = 58/123 (47%), Gaps = 10/123 (8%)
Query: 51 TGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEE 110
T DGS+ AS ++SS +E SE+ D E +G S E
Sbjct: 148 TPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG----SDHE----TGSSGSSDEQGNNTE 199
Query: 111 TEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQA 170
E E +E+++E+ EE EE+ EE+EE +E+ EEEEE+ + E+Y +E
Sbjct: 200 NEEEGVEEDVEED--EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQ 257
Query: 171 LEE 173
EE
Sbjct: 258 KEE 260
Score = 36.6 bits (83), Expect = 0.072
Identities = 31/141 (21%), Positives = 57/141 (40%), Gaps = 9/141 (6%)
Query: 22 SPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASED 81
S + V + E SD + +S S G+ +++ + G D + + E+
Sbjct: 166 SSQSSKEEVNSEEYGSDHETGSSGSS-DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEE 224
Query: 82 IELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEE 141
++ + E+ E E EEE E E+DE Q+E G + + E + E
Sbjct: 225 VDEDGEEEEEEEEEEEEE-------EEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSES 277
Query: 142 EEEEEEQPRAGPQGSGGNHEQ 162
+ R+G G+ G+ E+
Sbjct: 278 VSFTDGSVRSG-SGTDGSDEK 297
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 66.2 bits (160), Expect = 8e-11
Identities = 43/97 (44%), Positives = 52/97 (53%), Gaps = 7/97 (7%)
Query: 64 NDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEE 123
N + E ++E E+ E E EDFE E F EEE E EE +EE +EE
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFE-----EEEEEEEEFEEEFEEE 938
Query: 124 GGE--EEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGG 158
GE EEEEEE+EEEEEE EE E+ E AG + G
Sbjct: 939 EGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEG 975
Score = 63.2 bits (152), Expect = 7e-10
Identities = 37/68 (54%), Positives = 45/68 (66%), Gaps = 2/68 (2%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEE--EEEEEEEEQPRAGPQGSGGNHEQYSL 165
EEE E EEE+EE +EE EEE+ EEEEE+EEE EEEEEEEE+ + G E+
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
Query: 166 EEDQALEE 173
EED+ EE
Sbjct: 948 EEDEEEEE 955
Score = 59.7 bits (143), Expect = 8e-09
Identities = 33/66 (50%), Positives = 42/66 (63%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEE 167
EEE E EEE+EE +EE + EEEEE+EEE EEEEEEEEE + G E+ E+
Sbjct: 891 EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEED 950
Query: 168 DQALEE 173
++ EE
Sbjct: 951 EEEEEE 956
Score = 59.3 bits (142), Expect = 1e-08
Identities = 35/67 (52%), Positives = 42/67 (62%), Gaps = 2/67 (2%)
Query: 108 EEETEREEEDEEIQEEGGEEEE--EEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSL 165
EEE E EEE+E+ +EE +EEE EEEEEEEEE EEE EEEE + E+ L
Sbjct: 898 EEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957
Query: 166 EEDQALE 172
EE + LE
Sbjct: 958 EEVEDLE 964
Score = 52.4 bits (124), Expect = 1e-06
Identities = 30/65 (46%), Positives = 37/65 (56%)
Query: 114 EEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
EE+ I +EEEEEEEEEEEEEEEEEEEEE + E+ EE++ EE
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934
Query: 174 WVSSE 178
+ E
Sbjct: 935 FEEEE 939
Score = 51.2 bits (121), Expect = 3e-06
Identities = 31/71 (43%), Positives = 41/71 (57%), Gaps = 11/71 (15%)
Query: 104 PLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQY 163
P + E+ T + +EE EEEEEEEEEEEEEEE+ EEEEE + E+Y
Sbjct: 872 PALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEE-----------DEEEY 920
Query: 164 SLEEDQALEEW 174
EE++ EE+
Sbjct: 921 FEEEEEEEEEF 931
Score = 30.8 bits (68), Expect = 4.0
Identities = 36/146 (24%), Positives = 48/146 (32%), Gaps = 22/146 (15%)
Query: 62 FPNDASTENRSSDQESASEDIELESLEDFEHFLMSGE-----------SLFHYPLVGEEE 110
F + ++E E+ ELE +ED E GE P +
Sbjct: 935 FEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPK 994
Query: 111 TEREEEDE-----EIQEEGGEEEEEEE------EEEEEEEEEEEEEEEQPRAGPQGSGGN 159
+ E E E E++E G EEE + E + E E E E P AGP
Sbjct: 995 VQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELV 1054
Query: 160 HEQYSLEEDQALEEWVSSETSALPRP 185
E+ S EE P P
Sbjct: 1055 EEEPSAPPTLLEEETEDGSDKVQPPP 1080
Score = 29.6 bits (65), Expect = 8.8
Identities = 16/43 (37%), Positives = 24/43 (55%)
Query: 104 PLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEE 146
P + EEETE + + E EEE E E E E +E+E+++
Sbjct: 1062 PTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 63.9 bits (154), Expect = 4e-10
Identities = 42/115 (36%), Positives = 59/115 (51%), Gaps = 5/115 (4%)
Query: 69 ENRSSDQESASEDIELESLEDFEHFLMSGESLF-----HYPLVGEEETEREEEDEEIQEE 123
E + D+ +++ +E EHF ESL L EEE EREEE+E +EE
Sbjct: 2202 EAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEE 2261
Query: 124 GGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSE 178
EEEEE +EEEE EE++ E+EEE+ + + Q E + EE +S E
Sbjct: 2262 VREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEE 2316
Score = 54.7 bits (130), Expect = 3e-07
Identities = 39/129 (30%), Positives = 69/129 (53%), Gaps = 4/129 (3%)
Query: 56 DSRDGGFPND--ASTENRSSDQESASEDIE--LESLEDFEHFLMSGESLFHYPLVGEEET 111
+++ G P + +S + +E SE++E L+ LE E E EEE
Sbjct: 2202 EAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEE 2261
Query: 112 EREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQAL 171
REEE+E +EE GEE++ E+EEEE++++++E+++E+ + + E S EE ++L
Sbjct: 2262 VREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESL 2321
Query: 172 EEWVSSETS 180
+ E S
Sbjct: 2322 SDEEEEEES 2330
Score = 52.8 bits (125), Expect = 1e-06
Identities = 43/144 (29%), Positives = 73/144 (50%), Gaps = 7/144 (4%)
Query: 67 STENRSSDQESASEDIEL-ESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGG 125
S E+ S + ES +++E ESL E E V EEE ER+EE+E +++
Sbjct: 2222 SEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVE 2281
Query: 126 EEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSL------EEDQALEEWVSSET 179
+EEEE++++++E+++EE +E+E+ + E SL EE +LEE V E
Sbjct: 2282 KEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341
Query: 180 SALPRPRWQVVTALHQRQLGSRPR 203
L + + + ++ L R R
Sbjct: 2342 EILKKEKQFKLQEQRRKSLRGRER 2365
Score = 39.3 bits (90), Expect = 0.011
Identities = 27/82 (32%), Positives = 42/82 (51%)
Query: 97 GESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGS 156
GE+ + EE +R ++EE + GE+ EEE +E+++ + EE +Q S
Sbjct: 1472 GETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSS 1531
Query: 157 GGNHEQYSLEEDQALEEWVSSE 178
+QY EE+ LEE VS E
Sbjct: 1532 KSKEQQYKDEEEVTLEEEVSRE 1553
Score = 35.4 bits (80), Expect = 0.16
Identities = 26/105 (24%), Positives = 51/105 (48%), Gaps = 6/105 (5%)
Query: 69 ENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEE 128
E S ++E ED +L+ +E + E++ +E+ ++EE+ ++EE E
Sbjct: 1501 EKLSPEEEMLQEDKKLK----WEEWKQVWENMLSSK--SKEQQYKDEEEVTLEEEVSREG 1554
Query: 129 EEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
EE+E++ EE+ +EE + R + + ++ E A EE
Sbjct: 1555 EEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEE 1599
Score = 32.3 bits (72), Expect = 1.4
Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 29/91 (31%)
Query: 109 EETEREEEDEEIQEEGGEEEEEEE---------------------EEEEEEEEEEEEEEE 147
+E +R ++ +E +E E EE EEEEE EEEEE EEE
Sbjct: 2201 KEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEE 2260
Query: 148 QPRAGPQGSGGNHEQYSLEEDQALEEWVSSE 178
+ R E+ EE++ E+ V E
Sbjct: 2261 EVR--------EEEEERKEEEEGEEKQVEKE 2283
Score = 30.4 bits (67), Expect = 5.2
Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 13/107 (12%)
Query: 83 ELESLE-DFEHFLMSGESLFHYP--LVGEEETEREEED------EEIQEEGGEEEEEEEE 133
ELE LE D E E L LV E++ EEE+ E++ EE + +EEE
Sbjct: 1717 ELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEEL 1776
Query: 134 EEEEEEEEEEEEEEQPRAGPQGSGGNHEQY---SLEEDQALEEWVSS 177
+E+E+ + +E+ P + G EQ ++ Q E W++S
Sbjct: 1777 LIQEKEKLAQHKEKMPEE-EERLGRKREQLIEKKMKLAQKRERWINS 1822
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 63.5 bits (153), Expect = 6e-10
Identities = 32/51 (62%), Positives = 38/51 (74%)
Query: 105 LVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQG 155
L + E EEE+EE +EE E EEEEEE+EEEEEEEEEEEEE+P+ QG
Sbjct: 354 LASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQG 404
Score = 63.2 bits (152), Expect = 7e-10
Identities = 30/44 (68%), Positives = 35/44 (79%)
Query: 114 EEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSG 157
++EDEE +EEG EEEEE EEEEEE+EEEEEEEEE+ PQ G
Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRG 402
Score = 62.4 bits (150), Expect = 1e-09
Identities = 31/52 (59%), Positives = 38/52 (73%)
Query: 105 LVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGS 156
L +E+ E EEE EE +EE EEEEE+EEEEEEEEEEEEEE +Q G + +
Sbjct: 357 LSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSA 408
Score = 52.4 bits (124), Expect = 1e-06
Identities = 28/47 (59%), Positives = 34/47 (72%), Gaps = 1/47 (2%)
Query: 108 EEETEREEEDEEIQEEGGE-EEEEEEEEEEEEEEEEEEEEEQPRAGP 153
EEE E EEE+EE +EE E EEEEEEEEEEEEEE ++ + + A P
Sbjct: 364 EEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATP 410
Score = 45.8 bits (107), Expect = 1e-04
Identities = 23/44 (52%), Positives = 28/44 (63%)
Query: 107 GEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPR 150
GEEE E EE+EE EE EEEEEEEEEE ++ + E+ R
Sbjct: 369 GEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSR 412
Score = 38.9 bits (89), Expect = 0.015
Identities = 43/145 (29%), Positives = 62/145 (42%), Gaps = 30/145 (20%)
Query: 10 GLPDLGTESLFSSPEEQSGAVAATEASSD-IDIATSELSVTVTGD-GSDSRDG---GFPN 64
GLP L +L ++ A+A EA +D ++ +L+ G+ G + GF N
Sbjct: 291 GLPKLKELNLSFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGF-N 349
Query: 65 DASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEG 124
A SD E E+ E E E+ EE E E+E+E
Sbjct: 350 MAKVLASLSDDEDEEEEEEGEEEEE-----------------EAEEEEEEDEEE------ 386
Query: 125 GEEEEEEEEEEEEEEEEEEEEEEQP 149
EEEEEEEEEEE ++ + E+ P
Sbjct: 387 -EEEEEEEEEEEPQQRGQGEKSATP 410
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 63.2 bits (152), Expect = 7e-10
Identities = 47/131 (35%), Positives = 64/131 (48%), Gaps = 26/131 (19%)
Query: 49 TVTGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGE 108
TV D S R D S E + +++ S + + ES E E G
Sbjct: 469 TVVKDRSHLR-----KDDSEEEKEKEEDPGSHEEDDESSEQGEK--------------GT 509
Query: 109 EETEREEEDEEIQEEGG------EEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQ 162
R++EDEE +EEG EEEEEE++EEEEEEE+EE EE+ G S +H +
Sbjct: 510 HHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLS-PDHSE 568
Query: 163 YSLEEDQALEE 173
EE++ LEE
Sbjct: 569 EEEEEEEGLEE 579
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/131 (28%), Positives = 54/131 (41%), Gaps = 25/131 (19%)
Query: 63 PNDASTENRSSDQESASEDIELE-----------SLEDFEHFLMSGESLFHYPLVGEEET 111
P S +++ D+ + E++ E ED E S E H P
Sbjct: 104 PGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTED---SAEHRHHLPSHRSHSH 160
Query: 112 EREEEDEEIQEEGGEE---------EEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQ 162
+ E+EDE + E + E++E EEEEEEEEEEEE G Q H
Sbjct: 161 QDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAH--RHRG 218
Query: 163 YSLEEDQALEE 173
+ EED+ + +
Sbjct: 219 HGSEEDEDVSD 229
Score = 43.1 bits (100), Expect = 8e-04
Identities = 36/152 (23%), Positives = 65/152 (42%), Gaps = 31/152 (20%)
Query: 52 GDGS-DSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFH-YPLVGEE 109
G GS D+ D +RS + ED E+ S E H L G GEE
Sbjct: 136 GHGSEDTEDSAEHRHHLPSHRSHSHQDEDED-EVVSSEHHHHILRHGHRGHDGEDDEGEE 194
Query: 110 ETEREEEDEEIQEE-----------GGEEEEE-----------------EEEEEEEEEEE 141
E E EEE+EE E G EE+E+ EE+++++++++
Sbjct: 195 EEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDD 254
Query: 142 EEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
++++++ + H+ + +EED+ + +
Sbjct: 255 DDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSD 286
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/115 (32%), Positives = 48/115 (41%), Gaps = 13/115 (11%)
Query: 64 NDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEE 123
+D S+E S D E E E+ H L + ++E E EEEDEE +EE
Sbjct: 498 DDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEE---DKEEEEEEEDEERREE 554
Query: 124 GGE----------EEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEED 168
E EEEEEEEE EE+E P + +GG + ED
Sbjct: 555 RAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGASSEEESGED 609
Score = 35.4 bits (80), Expect = 0.16
Identities = 33/122 (27%), Positives = 45/122 (36%), Gaps = 17/122 (13%)
Query: 55 SDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETERE 114
S D +D STE Q +D E +E +SGE H P + E
Sbjct: 299 SHEEDDNDDDDVSTEY--GHQAHRHQDHRKEEVE-----AVSGEHHHHVPDHRHQGHRDE 351
Query: 115 EEDEEIQEEGGEEEEEEEEEEEEEEEEEEEE----------EEQPRAGPQGSGGNHEQYS 164
EEDE++ E + + +EEEEEEE QPR ++Y
Sbjct: 352 EEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYK 411
Query: 165 LE 166
E
Sbjct: 412 TE 413
Score = 33.9 bits (76), Expect = 0.47
Identities = 33/152 (21%), Positives = 57/152 (37%), Gaps = 18/152 (11%)
Query: 40 DIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDI-------------ELES 86
++ +SE + G DG E ++E AS + E E
Sbjct: 167 EVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDED 226
Query: 87 LEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEE 146
+ D H G S H G EE + +++D++ ++ + E + + EE+
Sbjct: 227 VSDGHHH--HGPSHRHQ---GHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEED 281
Query: 147 EQPRAGPQGSGGNHEQYSLEEDQALEEWVSSE 178
E G +H S EED ++ VS+E
Sbjct: 282 EDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTE 313
Score = 31.6 bits (70), Expect = 2.3
Identities = 32/111 (28%), Positives = 41/111 (36%), Gaps = 16/111 (14%)
Query: 53 DGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETE 112
D D D + S ++E E+ E E E E G L P EEE E
Sbjct: 515 DQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLS--PDHSEEEEE 572
Query: 113 REE---EDE-----------EIQEEGGEEEEEEEEEEEEEEEEEEEEEEQP 149
EE EDE +E GG EEE E+ ++ +E QP
Sbjct: 573 EEEGLEEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGPQDAQEYGNYQP 623
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 63.2 bits (152), Expect = 7e-10
Identities = 30/45 (66%), Positives = 37/45 (82%)
Query: 109 EETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGP 153
+E+ EEE+EE +EE EEEEEEE+EEEEEEEEEEEEEE ++ P
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSP 1110
Score = 60.8 bits (146), Expect = 4e-09
Identities = 32/57 (56%), Positives = 38/57 (66%), Gaps = 4/57 (7%)
Query: 104 PLVGEE----ETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGS 156
P+ GE E +E +EE +EE EEEEEEEEEEE+EEEEEEEEEE+ Q S
Sbjct: 1053 PVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSS 1109
Score = 60.8 bits (146), Expect = 4e-09
Identities = 29/49 (59%), Positives = 38/49 (77%)
Query: 106 VGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQ 154
+ +E +E EEE+E+ +EE EEEEEE+EEEEEEEEEEEEEE + P+
Sbjct: 1064 LSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPR 1112
Score = 58.2 bits (139), Expect = 2e-08
Identities = 36/77 (46%), Positives = 45/77 (58%)
Query: 72 SSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEE 131
+S Q A + + L E ++GE L E E EEE++E +EE EEEEE+
Sbjct: 1031 NSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEED 1090
Query: 132 EEEEEEEEEEEEEEEEQ 148
EEEEEEEEEEEEEE Q
Sbjct: 1091 EEEEEEEEEEEEEENIQ 1107
Score = 53.9 bits (128), Expect = 4e-07
Identities = 27/47 (57%), Positives = 32/47 (68%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQ 154
EEE E +EE+EE +EE E+EEEEEEEEEEEEEE + PQ
Sbjct: 1071 EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117
Score = 49.7 bits (117), Expect = 8e-06
Identities = 29/71 (40%), Positives = 40/71 (56%), Gaps = 10/71 (14%)
Query: 116 EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWV 175
E ++ E E EEEEEEE+EEEEEEEEEEE+ + E+ EE++ EE +
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEE----------DEEEEEEEEEEEEEENI 1106
Query: 176 SSETSALPRPR 186
S L +P+
Sbjct: 1107 QSSPPRLTKPQ 1117
Score = 49.3 bits (116), Expect = 1e-05
Identities = 37/108 (34%), Positives = 51/108 (47%), Gaps = 32/108 (29%)
Query: 108 EEETEREEEDEEIQEEGGEEEE--------------EEEEEEE-----------EEEEEE 142
EEE E EEE+EE +EE GEEEE +E+EE E ++ EEE
Sbjct: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEE 1411
Query: 143 EEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETSALPRPRWQVV 190
EEE+E+P N + + +ED + E E LPR ++ V
Sbjct: 1412 EEEDEEP-------SHNEDHDADDEDDSHMESAEVEKEELPRESFKEV 1452
Score = 46.6 bits (109), Expect = 7e-05
Identities = 35/105 (33%), Positives = 49/105 (46%), Gaps = 16/105 (15%)
Query: 69 ENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEET-----------EREEED 117
+ +S+ +++ I +E E +GE+L EET E+ E+D
Sbjct: 1292 QKETSEGKTSPSPIRIE-----EEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDD 1346
Query: 118 EEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQ 162
EE EEEEEEEEEEEEEE EEEE P G+ ++
Sbjct: 1347 LIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKE 1391
Score = 46.2 bits (108), Expect = 9e-05
Identities = 22/44 (50%), Positives = 30/44 (68%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRA 151
EE+ E EEE+EE +E+ EEEEEEEEEEEE + +P++
Sbjct: 1075 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQS 1118
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 61.6 bits (148), Expect = 2e-09
Identities = 40/95 (42%), Positives = 50/95 (52%), Gaps = 13/95 (13%)
Query: 53 DGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETE 112
D D DG D E+ + +++ E ED E G+ EEE E
Sbjct: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEE-----GDR--------EEEEE 134
Query: 113 REEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEE 147
EEEDE+ E+G + E+EEEEEEEEEEEEEEEE E
Sbjct: 135 IEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENE 169
Score = 53.5 bits (127), Expect = 6e-07
Identities = 28/66 (42%), Positives = 38/66 (57%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEE 167
+EE E EE E+ E G E+EE+EE + EEEEE EEE+E+ G E+ EE
Sbjct: 102 KEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE 161
Query: 168 DQALEE 173
++ EE
Sbjct: 162 EEEEEE 167
Score = 52.4 bits (124), Expect = 1e-06
Identities = 27/88 (30%), Positives = 49/88 (55%), Gaps = 6/88 (6%)
Query: 74 DQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEE 133
D +ED++ + ++ E + + G+E+ E EE D E +EE EE+E+++E
Sbjct: 91 DDSDGTEDMDEKEEDEGEEYSEDNDE------PGDEDEEDEEGDREEEEEIEEEDEDDDE 144
Query: 134 EEEEEEEEEEEEEEQPRAGPQGSGGNHE 161
+ E+ E+EEEEEEE+ + +H+
Sbjct: 145 DGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
Score = 50.1 bits (118), Expect = 6e-06
Identities = 28/72 (38%), Positives = 41/72 (56%), Gaps = 5/72 (6%)
Query: 107 GEEETEREEEDE-----EIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHE 161
G E+ + +EEDE E +E G+E+EE+EE + EEEEE EEE+E + E
Sbjct: 95 GTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEE 154
Query: 162 QYSLEEDQALEE 173
+ EE++ EE
Sbjct: 155 EEEEEEEEEEEE 166
Score = 47.4 bits (111), Expect = 4e-05
Identities = 39/146 (26%), Positives = 62/146 (42%), Gaps = 27/146 (18%)
Query: 22 SPEEQSGAVAATEAS---SDIDIATSELSVTVTGDGSD-SRDGGFPNDASTENRSSDQES 77
+P+ + AV A +S D T ++ +G + S D P D E+ D+E
Sbjct: 72 APKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREE 131
Query: 78 ASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEE 137
E+IE E +E+ + + ED E +EE EEEEEEEEEEE
Sbjct: 132 -EEEIEEE----------------------DEDDDEDGEDVEDEEEEEEEEEEEEEEEEN 168
Query: 138 EEEEEEEEEEQPRAGPQGSGGNHEQY 163
E+ + + + N+++Y
Sbjct: 169 EDHQMNCHNTRIMQDTEKDDNNNDEY 194
Score = 33.5 bits (75), Expect = 0.61
Identities = 15/51 (29%), Positives = 26/51 (50%)
Query: 118 EEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEED 168
+E + G E+ +E+EE+E EE E+ +E G E+ +EE+
Sbjct: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEE 138
Score = 33.5 bits (75), Expect = 0.61
Identities = 17/60 (28%), Positives = 33/60 (55%)
Query: 114 EEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E +D + E+ E+EE+E EE E+ +E +E+E+ G + E+ ++D+ E+
Sbjct: 89 ECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGED 148
Score = 32.0 bits (71), Expect = 1.8
Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 20/82 (24%)
Query: 117 DEEIQEEGGEEEEEEEEEEEEE--------------------EEEEEEEEEQPRAGPQGS 156
DE +G E+ +E+EE+E EE EEEEE EEE G
Sbjct: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGE 147
Query: 157 GGNHEQYSLEEDQALEEWVSSE 178
E+ EE++ EE +E
Sbjct: 148 DVEDEEEEEEEEEEEEEEEENE 169
Score = 29.6 bits (65), Expect = 8.8
Identities = 17/88 (19%), Positives = 42/88 (47%), Gaps = 8/88 (9%)
Query: 99 SLFHYPLVGEEETEREEEDEE--------IQEEGGEEEEEEEEEEEEEEEEEEEEEEQPR 150
S++ PL + +T+ ++ E ++ + +E ++ + E+ +E+EE+E +
Sbjct: 51 SVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEY 110
Query: 151 AGPQGSGGNHEQYSLEEDQALEEWVSSE 178
+ G+ ++ E D+ EE + E
Sbjct: 111 SEDNDEPGDEDEEDEEGDREEEEEIEEE 138
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 83 ELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE 142
+L+ + D E S ES G EE E EEE+EE EEG EE EEEEEEEEEEEE
Sbjct: 253 DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE--EEGSTSEESEEEEEEEEEEEE 310
Query: 143 EEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E A Q + E+ E+++ E
Sbjct: 311 ETGSNSEEASEQSAEEVSEEEMSEDEERENE 341
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Query: 66 ASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI---QE 122
+S E+ S++ S SE+ E E E+ E S ES EEE E EEE+EE E
Sbjct: 265 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES-------EEEEEEEEEEEEETGSNSE 317
Query: 123 EGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E E+ EE EEE E+EE E E P+ ++ S E ++A EE
Sbjct: 318 EASEQSAEEVSEEEMSEDEERENENHLLVVPE---SRFDRDSGESEEAEEE 365
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/126 (27%), Positives = 47/126 (37%), Gaps = 2/126 (1%)
Query: 40 DIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGES 99
DI+ SE + S G + E ++ S SE+ E E E+ E +G +
Sbjct: 256 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 315
Query: 100 LFHYPLVGEEETEREE--EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSG 157
EE EE EDEE + E E + + E EE EEE PQ S
Sbjct: 316 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 375
Query: 158 GNHEQY 163
Y
Sbjct: 376 LTEGDY 381
Score = 36.2 bits (82), Expect = 0.094
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 98 ESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE-----------EEEE 146
E + L+ + + + E + E E EEEEEEEEE EEEE
Sbjct: 243 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 302
Query: 147 EQPRAGPQGSGGNHEQYSLEEDQALEEWVSSE 178
E+ + +G N E+ S + + + E SE
Sbjct: 303 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 334
Score = 33.1 bits (74), Expect = 0.80
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 3/77 (3%)
Query: 106 VGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEE---EEEEEEEQPRAGPQGSGGNHEQ 162
V EE+ E + ++Q+ E + E E EEEEEE+ +GS +
Sbjct: 240 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 299
Query: 163 YSLEEDQALEEWVSSET 179
EE++ EE S +
Sbjct: 300 EEEEEEEEEEEETGSNS 316
Score = 31.2 bits (69), Expect = 3.0
Identities = 15/39 (38%), Positives = 21/39 (53%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEE 146
E + ERE + E Q+E E++E E EE +E E E
Sbjct: 160 ERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 198
Score = 30.0 bits (66), Expect = 6.7
Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 4/138 (2%)
Query: 110 ETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQ 169
E ER++ E +E E + E+ E + E E + E+Q Q + +E +
Sbjct: 135 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 194
Query: 170 ALEEWVSSETSALPRPRWQVVTALHQRQLGSR-PRFVYEACGARAFVQRFRLQYRLADHV 228
A E VS+ + V A H + R PR +E R V+ +++ R D +
Sbjct: 195 ARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER--DLL 251
Query: 229 GCVNTVHFNQRGTRLASS 246
+ + ++R T A S
Sbjct: 252 SDLQDISDSERKTSSAES 269
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 83 ELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE 142
+L+ + D E S ES G EE E EEE+EE EEG EE EEEEEEEEEEEE
Sbjct: 263 DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE--EEGSTSEESEEEEEEEEEEEE 320
Query: 143 EEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E A Q + E+ E+++ E
Sbjct: 321 ETGSNSEEASEQSAEEVSEEEMSEDEERENE 351
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Query: 66 ASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI---QE 122
+S E+ S++ S SE+ E E E+ E S ES EEE E EEE+EE E
Sbjct: 275 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES-------EEEEEEEEEEEEETGSNSE 327
Query: 123 EGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E E+ EE EEE E+EE E E P+ ++ S E ++A EE
Sbjct: 328 EASEQSAEEVSEEEMSEDEERENENHLLVVPE---SRFDRDSGESEEAEEE 375
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/126 (27%), Positives = 47/126 (37%), Gaps = 2/126 (1%)
Query: 40 DIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGES 99
DI+ SE + S G + E ++ S SE+ E E E+ E +G +
Sbjct: 266 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 325
Query: 100 LFHYPLVGEEETEREE--EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSG 157
EE EE EDEE + E E + + E EE EEE PQ S
Sbjct: 326 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 385
Query: 158 GNHEQY 163
Y
Sbjct: 386 LTEGDY 391
Score = 36.2 bits (82), Expect = 0.094
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 98 ESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE-----------EEEE 146
E + L+ + + + E + E E EEEEEEEEE EEEE
Sbjct: 253 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 312
Query: 147 EQPRAGPQGSGGNHEQYSLEEDQALEEWVSSE 178
E+ + +G N E+ S + + + E SE
Sbjct: 313 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 344
Score = 33.1 bits (74), Expect = 0.80
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 3/77 (3%)
Query: 106 VGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEE---EEEEEEEQPRAGPQGSGGNHEQ 162
V EE+ E + ++Q+ E + E E EEEEEE+ +GS +
Sbjct: 250 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 309
Query: 163 YSLEEDQALEEWVSSET 179
EE++ EE S +
Sbjct: 310 EEEEEEEEEEEETGSNS 326
Score = 31.2 bits (69), Expect = 3.0
Identities = 15/39 (38%), Positives = 21/39 (53%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEE 146
E + ERE + E Q+E E++E E EE +E E E
Sbjct: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 208
Score = 30.0 bits (66), Expect = 6.7
Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 4/138 (2%)
Query: 110 ETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQ 169
E ER++ E +E E + E+ E + E E + E+Q Q + +E +
Sbjct: 145 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 204
Query: 170 ALEEWVSSETSALPRPRWQVVTALHQRQLGSR-PRFVYEACGARAFVQRFRLQYRLADHV 228
A E VS+ + V A H + R PR +E R V+ +++ R D +
Sbjct: 205 ARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER--DLL 261
Query: 229 GCVNTVHFNQRGTRLASS 246
+ + ++R T A S
Sbjct: 262 SDLQDISDSERKTSSAES 279
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 61.2 bits (147), Expect = 3e-09
Identities = 31/60 (51%), Positives = 44/60 (73%), Gaps = 4/60 (6%)
Query: 109 EETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEED 168
EE E EEE+EE++EE EEE+EE+EEEEE+EEE+EE+EE+ + G E+ +EE+
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE----EEKEGKKMEEEKVEEE 174
Score = 50.8 bits (120), Expect = 4e-06
Identities = 30/77 (38%), Positives = 48/77 (62%), Gaps = 6/77 (7%)
Query: 105 LVGEEETEREE---EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHE 161
LV EE + ++ E+EE++EE EEE EEEE+EEE+EE+EEEEE+ + +
Sbjct: 105 LVAEECSAQQGLPVEEEEVEEE---EEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK 161
Query: 162 QYSLEEDQALEEWVSSE 178
+ E++ +EE + +E
Sbjct: 162 EGKKMEEEKVEEEIDTE 178
Score = 43.5 bits (101), Expect = 6e-04
Identities = 23/43 (53%), Positives = 30/43 (69%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPR 150
+EE E EEE EE +EE EEEE+E ++ EEE+ EEE + E R
Sbjct: 139 KEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQR 181
Score = 38.9 bits (89), Expect = 0.015
Identities = 20/41 (48%), Positives = 28/41 (68%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQ 148
EEE E+EEE EE +EE +E ++ EEE+ EEE + E + Q
Sbjct: 143 EEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 83 ELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE 142
+L+ + D E S ES G EE E EEE+EE EEG EE EEEEEEEEEEEE
Sbjct: 254 DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE--EEGSTSEESEEEEEEEEEEEE 311
Query: 143 EEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E A Q + E+ E+++ E
Sbjct: 312 ETGSNSEEASEQSAEEVSEEEMSEDEERENE 342
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Query: 66 ASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI---QE 122
+S E+ S++ S SE+ E E E+ E S ES EEE E EEE+EE E
Sbjct: 266 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES-------EEEEEEEEEEEEETGSNSE 318
Query: 123 EGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E E+ EE EEE E+EE E E P+ ++ S E ++A EE
Sbjct: 319 EASEQSAEEVSEEEMSEDEERENENHLLVVPE---SRFDRDSGESEEAEEE 366
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/126 (27%), Positives = 47/126 (37%), Gaps = 2/126 (1%)
Query: 40 DIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGES 99
DI+ SE + S G + E ++ S SE+ E E E+ E +G +
Sbjct: 257 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 316
Query: 100 LFHYPLVGEEETEREE--EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSG 157
EE EE EDEE + E E + + E EE EEE PQ S
Sbjct: 317 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 376
Query: 158 GNHEQY 163
Y
Sbjct: 377 LTEGDY 382
Score = 36.2 bits (82), Expect = 0.094
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 98 ESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE-----------EEEE 146
E + L+ + + + E + E E EEEEEEEEE EEEE
Sbjct: 244 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 303
Query: 147 EQPRAGPQGSGGNHEQYSLEEDQALEEWVSSE 178
E+ + +G N E+ S + + + E SE
Sbjct: 304 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 335
Score = 33.1 bits (74), Expect = 0.80
Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 106 VGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEE-----EEEEEEEEQPRAGPQGSGGNH 160
V EE+ E + ++Q+ E + E E EEEEEEEE+ S +
Sbjct: 241 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 300
Query: 161 EQYSLEEDQALEEWVSSETSA 181
E+ EE++ E +SE ++
Sbjct: 301 EEEEEEEEEEEETGSNSEEAS 321
Score = 31.2 bits (69), Expect = 3.0
Identities = 15/39 (38%), Positives = 21/39 (53%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEE 146
E + ERE + E Q+E E++E E EE +E E E
Sbjct: 161 ERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 199
Score = 30.0 bits (66), Expect = 6.7
Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 4/138 (2%)
Query: 110 ETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQ 169
E ER++ E +E E + E+ E + E E + E+Q Q + +E +
Sbjct: 136 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 195
Query: 170 ALEEWVSSETSALPRPRWQVVTALHQRQLGSR-PRFVYEACGARAFVQRFRLQYRLADHV 228
A E VS+ + V A H + R PR +E R V+ +++ R D +
Sbjct: 196 ARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER--DLL 252
Query: 229 GCVNTVHFNQRGTRLASS 246
+ + ++R T A S
Sbjct: 253 SDLQDISDSERKTSSAES 270
Score = 29.6 bits (65), Expect = 8.8
Identities = 23/114 (20%), Positives = 53/114 (46%), Gaps = 5/114 (4%)
Query: 72 SSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETE-REEEDEEIQEEGGEEEEE 130
S D++S + +E L D H + ++ + P E+ E R EED+ + + ++
Sbjct: 38 SDDRDSKRDSLEEGELRD--HCMEI--TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSR 93
Query: 131 EEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETSALPR 184
+E+ ++E+ +E++ + +++ E+D+A EW + + R
Sbjct: 94 KEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR 147
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 83 ELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE 142
+L+ + D E S ES G EE E EEE+EE EEG EE EEEEEEEEEEEE
Sbjct: 263 DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE--EEGSTSEESEEEEEEEEEEEE 320
Query: 143 EEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E A Q + E+ E+++ E
Sbjct: 321 ETGSNSEEASEQSAEEVSEEEMSEDEERENE 351
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Query: 66 ASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI---QE 122
+S E+ S++ S SE+ E E E+ E S ES EEE E EEE+EE E
Sbjct: 275 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES-------EEEEEEEEEEEEETGSNSE 327
Query: 123 EGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E E+ EE EEE E+EE E E P+ ++ S E ++A EE
Sbjct: 328 EASEQSAEEVSEEEMSEDEERENENHLLVVPE---SRFDRDSGESEEAEEE 375
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/126 (27%), Positives = 47/126 (37%), Gaps = 2/126 (1%)
Query: 40 DIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGES 99
DI+ SE + S G + E ++ S SE+ E E E+ E +G +
Sbjct: 266 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 325
Query: 100 LFHYPLVGEEETEREE--EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSG 157
EE EE EDEE + E E + + E EE EEE PQ S
Sbjct: 326 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 385
Query: 158 GNHEQY 163
Y
Sbjct: 386 LTEGDY 391
Score = 36.2 bits (82), Expect = 0.094
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 98 ESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE-----------EEEE 146
E + L+ + + + E + E E EEEEEEEEE EEEE
Sbjct: 253 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 312
Query: 147 EQPRAGPQGSGGNHEQYSLEEDQALEEWVSSE 178
E+ + +G N E+ S + + + E SE
Sbjct: 313 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 344
Score = 33.1 bits (74), Expect = 0.80
Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 106 VGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEE-----EEEEEEEEQPRAGPQGSGGNH 160
V EE+ E + ++Q+ E + E E EEEEEEEE+ S +
Sbjct: 250 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 309
Query: 161 EQYSLEEDQALEEWVSSETSA 181
E+ EE++ E +SE ++
Sbjct: 310 EEEEEEEEEEEETGSNSEEAS 330
Score = 31.2 bits (69), Expect = 3.0
Identities = 15/39 (38%), Positives = 21/39 (53%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEE 146
E + ERE + E Q+E E++E E EE +E E E
Sbjct: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 208
Score = 29.6 bits (65), Expect = 8.8
Identities = 23/114 (20%), Positives = 53/114 (46%), Gaps = 5/114 (4%)
Query: 72 SSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETE-REEEDEEIQEEGGEEEEE 130
S D++S + +E L D H + ++ + P E+ E R EED+ + + ++
Sbjct: 38 SDDRDSKRDSLEEGELRD--HCMEI--TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSR 93
Query: 131 EEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETSALPR 184
+E+ ++E+ +E++ + +++ E+D+A EW + + R
Sbjct: 94 KEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR 147
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 83 ELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE 142
+L+ + D E S ES G EE E EEE+EE EEG EE EEEEEEEEEEEE
Sbjct: 231 DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE--EEGSTSEESEEEEEEEEEEEE 288
Query: 143 EEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E A Q + E+ E+++ E
Sbjct: 289 ETGSNSEEASEQSAEEVSEEEMSEDEERENE 319
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Query: 66 ASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI---QE 122
+S E+ S++ S SE+ E E E+ E S ES EEE E EEE+EE E
Sbjct: 243 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES-------EEEEEEEEEEEEETGSNSE 295
Query: 123 EGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E E+ EE EEE E+EE E E P+ ++ S E ++A EE
Sbjct: 296 EASEQSAEEVSEEEMSEDEERENENHLLVVPE---SRFDRDSGESEEAEEE 343
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/126 (27%), Positives = 47/126 (37%), Gaps = 2/126 (1%)
Query: 40 DIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGES 99
DI+ SE + S G + E ++ S SE+ E E E+ E +G +
Sbjct: 234 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 293
Query: 100 LFHYPLVGEEETEREE--EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSG 157
EE EE EDEE + E E + + E EE EEE PQ S
Sbjct: 294 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 353
Query: 158 GNHEQY 163
Y
Sbjct: 354 LTEGDY 359
Score = 36.2 bits (82), Expect = 0.094
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 98 ESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE-----------EEEE 146
E + L+ + + + E + E E EEEEEEEEE EEEE
Sbjct: 221 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 280
Query: 147 EQPRAGPQGSGGNHEQYSLEEDQALEEWVSSE 178
E+ + +G N E+ S + + + E SE
Sbjct: 281 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 312
Score = 33.1 bits (74), Expect = 0.80
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 3/77 (3%)
Query: 106 VGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEE---EEEEEEEQPRAGPQGSGGNHEQ 162
V EE+ E + ++Q+ E + E E EEEEEE+ +GS +
Sbjct: 218 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 277
Query: 163 YSLEEDQALEEWVSSET 179
EE++ EE S +
Sbjct: 278 EEEEEEEEEEEETGSNS 294
Score = 31.2 bits (69), Expect = 3.0
Identities = 15/39 (38%), Positives = 21/39 (53%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEE 146
E + ERE + E Q+E E++E E EE +E E E
Sbjct: 138 ERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 176
Score = 30.0 bits (66), Expect = 6.7
Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 4/138 (2%)
Query: 110 ETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQ 169
E ER++ E +E E + E+ E + E E + E+Q Q + +E +
Sbjct: 113 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 172
Query: 170 ALEEWVSSETSALPRPRWQVVTALHQRQLGSR-PRFVYEACGARAFVQRFRLQYRLADHV 228
A E VS+ + V A H + R PR +E R V+ +++ R D +
Sbjct: 173 ARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER--DLL 229
Query: 229 GCVNTVHFNQRGTRLASS 246
+ + ++R T A S
Sbjct: 230 SDLQDISDSERKTSSAES 247
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 83 ELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE 142
+L+ + D E S ES G EE E EEE+EE EEG EE EEEEEEEEEEEE
Sbjct: 220 DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE--EEGSTSEESEEEEEEEEEEEE 277
Query: 143 EEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E A Q + E+ E+++ E
Sbjct: 278 ETGSNSEEASEQSAEEVSEEEMSEDEERENE 308
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Query: 66 ASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI---QE 122
+S E+ S++ S SE+ E E E+ E S ES EEE E EEE+EE E
Sbjct: 232 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES-------EEEEEEEEEEEEETGSNSE 284
Query: 123 EGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E E+ EE EEE E+EE E E P+ ++ S E ++A EE
Sbjct: 285 EASEQSAEEVSEEEMSEDEERENENHLLVVPE---SRFDRDSGESEEAEEE 332
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/126 (27%), Positives = 47/126 (37%), Gaps = 2/126 (1%)
Query: 40 DIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGES 99
DI+ SE + S G + E ++ S SE+ E E E+ E +G +
Sbjct: 223 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 282
Query: 100 LFHYPLVGEEETEREE--EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSG 157
EE EE EDEE + E E + + E EE EEE PQ S
Sbjct: 283 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 342
Query: 158 GNHEQY 163
Y
Sbjct: 343 LTEGDY 348
Score = 36.2 bits (82), Expect = 0.094
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 98 ESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE-----------EEEE 146
E + L+ + + + E + E E EEEEEEEEE EEEE
Sbjct: 210 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 269
Query: 147 EQPRAGPQGSGGNHEQYSLEEDQALEEWVSSE 178
E+ + +G N E+ S + + + E SE
Sbjct: 270 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 301
Score = 33.1 bits (74), Expect = 0.80
Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 106 VGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEE-----EEEEEEEEQPRAGPQGSGGNH 160
V EE+ E + ++Q+ E + E E EEEEEEEE+ S +
Sbjct: 207 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 266
Query: 161 EQYSLEEDQALEEWVSSETSA 181
E+ EE++ E +SE ++
Sbjct: 267 EEEEEEEEEEEETGSNSEEAS 287
Score = 31.6 bits (70), Expect = 2.3
Identities = 23/116 (19%), Positives = 52/116 (44%), Gaps = 5/116 (4%)
Query: 70 NRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETE-REEEDEEIQEEGGEEE 128
++S D++S + +E L D + S P E+ E R EED+ + + ++
Sbjct: 2 SQSDDRDSKRDSLEEGELRDHRMEITIRNS----PYRREDSMEDRGEEDDSLAIKPPQQM 57
Query: 129 EEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETSALPR 184
+E+ ++E+ +E++ + +++ E+D+A EW + + R
Sbjct: 58 SRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR 113
Score = 31.2 bits (69), Expect = 3.0
Identities = 15/39 (38%), Positives = 21/39 (53%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEE 146
E + ERE + E Q+E E++E E EE +E E E
Sbjct: 127 ERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 165
Score = 30.0 bits (66), Expect = 6.7
Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 4/138 (2%)
Query: 110 ETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQ 169
E ER++ E +E E + E+ E + E E + E+Q Q + +E +
Sbjct: 102 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 161
Query: 170 ALEEWVSSETSALPRPRWQVVTALHQRQLGSR-PRFVYEACGARAFVQRFRLQYRLADHV 228
A E VS+ + V A H + R PR +E R V+ +++ R D +
Sbjct: 162 ARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER--DLL 218
Query: 229 GCVNTVHFNQRGTRLASS 246
+ + ++R T A S
Sbjct: 219 SDLQDISDSERKTSSAES 236
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 83 ELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE 142
+L+ + D E S ES G EE E EEE+EE EEG EE EEEEEEEEEEEE
Sbjct: 9 DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE--EEGSTSEESEEEEEEEEEEEE 66
Query: 143 EEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E A Q + E+ E+++ E
Sbjct: 67 ETGSNSEEASEQSAEEVSEEEMSEDEERENE 97
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Query: 66 ASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI---QE 122
+S E+ S++ S SE+ E E E+ E S ES EEE E EEE+EE E
Sbjct: 21 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES-------EEEEEEEEEEEEETGSNSE 73
Query: 123 EGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E E+ EE EEE E+EE E E P+ ++ S E ++A EE
Sbjct: 74 EASEQSAEEVSEEEMSEDEERENENHLLVVPE---SRFDRDSGESEEAEEE 121
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/126 (27%), Positives = 47/126 (37%), Gaps = 2/126 (1%)
Query: 40 DIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGES 99
DI+ SE + S G + E ++ S SE+ E E E+ E +G +
Sbjct: 12 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 71
Query: 100 LFHYPLVGEEETEREE--EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSG 157
EE EE EDEE + E E + + E EE EEE PQ S
Sbjct: 72 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 131
Query: 158 GNHEQY 163
Y
Sbjct: 132 LTEGDY 137
Score = 35.8 bits (81), Expect = 0.12
Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 11/85 (12%)
Query: 105 LVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE-----------EEEEEQPRAGP 153
L+ + + + E + E E EEEEEEEEE EEEEE+
Sbjct: 6 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 65
Query: 154 QGSGGNHEQYSLEEDQALEEWVSSE 178
+ +G N E+ S + + + E SE
Sbjct: 66 EETGSNSEEASEQSAEEVSEEEMSE 90
Score = 31.6 bits (70), Expect = 2.3
Identities = 18/71 (25%), Positives = 30/71 (42%)
Query: 109 EETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEED 168
EE + + ++I + + E E EEEEEE+ +GS + EE+
Sbjct: 2 EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEE 61
Query: 169 QALEEWVSSET 179
+ EE S +
Sbjct: 62 EEEEEETGSNS 72
Score = 30.0 bits (66), Expect = 6.7
Identities = 20/74 (27%), Positives = 31/74 (41%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEE 167
E + + +D E E E EEEEEEEE+ S + E+ EE
Sbjct: 3 ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 62
Query: 168 DQALEEWVSSETSA 181
++ E +SE ++
Sbjct: 63 EEEEETGSNSEEAS 76
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 83 ELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE 142
+L+ + D E S ES G EE E EEE+EE EEG EE EEEEEEEEEEEE
Sbjct: 265 DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE--EEGSTSEESEEEEEEEEEEEE 322
Query: 143 EEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E A Q + E+ E+++ E
Sbjct: 323 ETGSNSEEASEQSAEEVSEEEMSEDEERENE 353
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Query: 66 ASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI---QE 122
+S E+ S++ S SE+ E E E+ E S ES EEE E EEE+EE E
Sbjct: 277 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES-------EEEEEEEEEEEEETGSNSE 329
Query: 123 EGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
E E+ EE EEE E+EE E E P+ ++ S E ++A EE
Sbjct: 330 EASEQSAEEVSEEEMSEDEERENENHLLVVPE---SRFDRDSGESEEAEEE 377
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/126 (27%), Positives = 47/126 (37%), Gaps = 2/126 (1%)
Query: 40 DIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGES 99
DI+ SE + S G + E ++ S SE+ E E E+ E +G +
Sbjct: 268 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 327
Query: 100 LFHYPLVGEEETEREE--EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSG 157
EE EE EDEE + E E + + E EE EEE PQ S
Sbjct: 328 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 387
Query: 158 GNHEQY 163
Y
Sbjct: 388 LTEGDY 393
Score = 36.2 bits (82), Expect = 0.094
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 98 ESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE-----------EEEE 146
E + L+ + + + E + E E EEEEEEEEE EEEE
Sbjct: 255 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 314
Query: 147 EQPRAGPQGSGGNHEQYSLEEDQALEEWVSSE 178
E+ + +G N E+ S + + + E SE
Sbjct: 315 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 346
Score = 33.1 bits (74), Expect = 0.80
Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 106 VGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEE-----EEEEEEEEQPRAGPQGSGGNH 160
V EE+ E + ++Q+ E + E E EEEEEEEE+ S +
Sbjct: 252 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 311
Query: 161 EQYSLEEDQALEEWVSSETSA 181
E+ EE++ E +SE ++
Sbjct: 312 EEEEEEEEEEEETGSNSEEAS 332
Score = 31.2 bits (69), Expect = 3.0
Identities = 15/39 (38%), Positives = 21/39 (53%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEE 146
E + ERE + E Q+E E++E E EE +E E E
Sbjct: 172 ERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 210
Score = 30.0 bits (66), Expect = 6.7
Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 4/138 (2%)
Query: 110 ETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQ 169
E ER++ E +E E + E+ E + E E + E+Q Q + +E +
Sbjct: 147 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 206
Query: 170 ALEEWVSSETSALPRPRWQVVTALHQRQLGSR-PRFVYEACGARAFVQRFRLQYRLADHV 228
A E VS+ + V A H + R PR +E R V+ +++ R D +
Sbjct: 207 ARRE-VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER--DLL 263
Query: 229 GCVNTVHFNQRGTRLASS 246
+ + ++R T A S
Sbjct: 264 SDLQDISDSERKTSSAES 281
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 61.2 bits (147), Expect = 3e-09
Identities = 34/52 (65%), Positives = 38/52 (73%), Gaps = 8/52 (15%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEE--------EEEEEEEEEEEEEEEEQPRA 151
EEE E+EEE+EE +EEGG EE EE E EEEEEEEEEEEEEEQ +A
Sbjct: 228 EEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKA 279
Score = 56.2 bits (134), Expect = 9e-08
Identities = 35/84 (41%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 118 EEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSS 177
E I E EEEE+EEEEE+EEEEEE EEE G +G GG + + EE++ EE
Sbjct: 215 EVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEE 274
Query: 178 ETSAL---PRPRWQVVTALHQRQL 198
E + RWQ T + +L
Sbjct: 275 EQIKAFQEKQKRWQQPTGVRSWRL 298
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 27/126 (21%)
Query: 24 EEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDIE 83
EE A AA EA++ + A + V V D + E + ++E E+ E
Sbjct: 192 EEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEE------------EEKEEEEEKEEEEEE 239
Query: 84 LESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEE 143
E E G G E E EEE+E EEEEEEEEE+ + +E++
Sbjct: 240 GEEEGGGEEGEEGGG--------GGEGEETEEEEE-------EEEEEEEEEQIKAFQEKQ 284
Query: 144 EEEEQP 149
+ +QP
Sbjct: 285 KRWQQP 290
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 61.2 bits (147), Expect = 3e-09
Identities = 50/135 (37%), Positives = 69/135 (51%), Gaps = 15/135 (11%)
Query: 49 TVTGDGSDSRDGGFPNDASTENRSSD---QESASEDIELESLEDFEHFLMSGESLFHYPL 105
TV+G+ S +R G NDA QE+ ++ SL F +SL PL
Sbjct: 220 TVSGEASPARSSG--NDAPPGGSKETWGLQETLYGFVQNPSLA-FSPNPEENQSLA--PL 274
Query: 106 VGEEETEREEEDEEIQE-------EGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGG 158
+ EEE E++ +DEE + E EEEEE E+EEEE E+EEEEE E+ +G
Sbjct: 275 LVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEE 334
Query: 159 NHEQYSLEEDQALEE 173
E+ EE++ LEE
Sbjct: 335 LEEEELEEEEEVLEE 349
Score = 50.4 bits (119), Expect = 5e-06
Identities = 29/71 (40%), Positives = 42/71 (59%)
Query: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEE 167
EEE E E+E+EE+++E EE EE E EE EEE EEEE E+ + + E++ L
Sbjct: 302 EEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPL 361
Query: 168 DQALEEWVSSE 178
+ L +V +E
Sbjct: 362 EMPLSIFVEAE 372
Score = 43.1 bits (100), Expect = 8e-04
Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 22/89 (24%)
Query: 69 ENRSSDQESASEDI--------ELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI 120
E ++ D+E +++ E E +ED E + E+E E E E+ E
Sbjct: 281 EKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEV-------------EDEEEEEVEEAEY 327
Query: 121 QEEGGEEEEEEE-EEEEEEEEEEEEEEEQ 148
EEG EE EEEE EEEEE EE E+ E+
Sbjct: 328 VEEGEEELEEEELEEEEEVLEENEQRGEE 356
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 60.8 bits (146), Expect = 4e-09
Identities = 62/219 (28%), Positives = 99/219 (45%), Gaps = 24/219 (10%)
Query: 1 MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDG 60
M +EG T G G S E Q TE + E GD ++ D
Sbjct: 756 MPGEEGETAGE---GETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGD-NEGEDE 811
Query: 61 GFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI 120
G + E + ++ E+ S+++ E+ + ++ E G + + EEE+EE
Sbjct: 812 GEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGG-----GSDGGDSEEEEEEE 866
Query: 121 QEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLE-EDQALEEWVSSET 179
+E+ EEEEEEEE+EEEEEEEEEEEE+ GN E SL+ + ++ +
Sbjct: 867 EEQ---EEEEEEEEQEEEEEEEEEEEEK---------GNEEPLSLDWPETRQKQAIYLFL 914
Query: 180 SALPRPRWQVVTALHQRQLGSRPRFVYEACGARAFVQRF 218
+ P W V + +++ SR FV+ G+ ++ F
Sbjct: 915 LPIVFPLWLTVPDVRRQE--SRKFFVFTFLGSIMWIAMF 951
>gi|147904340 WD repeat domain 82 [Homo sapiens]
Length = 313
Score = 60.5 bits (145), Expect = 5e-09
Identities = 75/336 (22%), Positives = 126/336 (37%), Gaps = 40/336 (11%)
Query: 215 VQRFRLQYRLADHVGCVNTVHFNQRGTRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNV 274
++ FR+ ++ +N F+ G + SS DD ++++D +P S V
Sbjct: 8 LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYS-KKYGV 66
Query: 275 FQAKFLPNCGDSTLAMCARDGQVRVAELINASYFNNTKCVAQHRGPAHKLALEPDSPYKF 334
++ + D +R L + Y + H L++ P F
Sbjct: 67 DLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYI---RYFPGHSKRVVALSMSPVDD-TF 122
Query: 335 LTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTITVNPANTYQ-----FAVGGQDQ 389
++ D + DLR GL + P ++ FA G +
Sbjct: 123 ISGSLDKTIRLWDLRSPNCQ-------------GLMHLQGKPVCSFDPEGLIFAAGVNSE 169
Query: 390 FVRIYDQRKIDKKENNGVLKKFTPHHLVNCDFPTNITCVVYSHDGTELLASYNDDDIYLF 449
V++YD R DK G F + C++ T + +S+DG +L S N I L
Sbjct: 170 MVKLYDLRSFDK----GPFATFKMQYDRTCEW----TGLKFSNDGKLILISTNGSFIRLI 221
Query: 450 NSSHSDGAQYSKRFKGHRNNTTVKGVNFYGPRSEFVVSGSDCGHIFFWEKSSCQIIQFLK 509
++ F G+ N+ V + P S+F++ GS+ G I W S + L
Sbjct: 222 DAFKG---VVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLD 278
Query: 510 GSREGTINCLEPHPYLPVL--ACSGLDHDVKIWTPT 543
G G I CL+ +P ACS ++ W PT
Sbjct: 279 GKHTGPITCLQFNPKFMTFASACS----NMAFWLPT 310
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,172,423
Number of Sequences: 37866
Number of extensions: 1468797
Number of successful extensions: 77589
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1242
Number of HSP's successfully gapped in prelim test: 454
Number of HSP's that attempted gapping in prelim test: 18414
Number of HSP's gapped (non-prelim): 20586
length of query: 631
length of database: 18,247,518
effective HSP length: 108
effective length of query: 523
effective length of database: 14,157,990
effective search space: 7404628770
effective search space used: 7404628770
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.