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Search of human proteins with 21071070
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21071070 transmembrane channel-like 1 [Homo sapiens]
(760 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21071070 transmembrane channel-like 1 [Homo sapiens] 1549 0.0
gi|94536852 transmembrane cochlear-expressed protein 2 [Homo sap... 893 0.0
gi|122937502 transmembrane channel-like 3 [Homo sapiens] 576 e-164
gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens] 229 7e-60
gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens] 229 7e-60
gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens] 176 6e-44
gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens] 176 6e-44
gi|23943900 transmembrane channel-like 8 [Homo sapiens] 152 1e-36
gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens] 138 2e-32
gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens] 138 2e-32
gi|187608784 transmembrane channel-like 6 [Homo sapiens] 134 3e-31
gi|187608791 transmembrane channel-like 6 [Homo sapiens] 134 3e-31
gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens] 120 5e-27
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 64 7e-10
gi|221219020 NYD-SP11 protein [Homo sapiens] 58 4e-08
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 54 5e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 54 7e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 52 2e-06
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 52 2e-06
gi|148746195 trichohyalin [Homo sapiens] 52 2e-06
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 52 2e-06
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 52 2e-06
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 52 2e-06
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 52 2e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 52 3e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 52 3e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 51 3e-06
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 50 6e-06
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 50 1e-05
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 49 1e-05
>gi|21071070 transmembrane channel-like 1 [Homo sapiens]
Length = 760
Score = 1549 bits (4010), Expect = 0.0
Identities = 760/760 (100%), Positives = 760/760 (100%)
Query: 1 MSPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPED 60
MSPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPED
Sbjct: 1 MSPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPED 60
Query: 61 EETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVL 120
EETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVL
Sbjct: 61 EETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVL 120
Query: 121 KEAKKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQ 180
KEAKKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQ
Sbjct: 121 KEAKKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQ 180
Query: 181 FGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANF 240
FGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANF
Sbjct: 181 FGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANF 240
Query: 241 GVLYDFNGLAQYSVLFYGYYDNKRTIGWMNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNI 300
GVLYDFNGLAQYSVLFYGYYDNKRTIGWMNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNI
Sbjct: 241 GVLYDFNGLAQYSVLFYGYYDNKRTIGWMNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNI 300
Query: 301 GDDGGGDDNTFNFSWKVFTSWDYLIGNPETADNKFNSITMNFKEAITEEKAAQVEENVHL 360
GDDGGGDDNTFNFSWKVFTSWDYLIGNPETADNKFNSITMNFKEAITEEKAAQVEENVHL
Sbjct: 301 GDDGGGDDNTFNFSWKVFTSWDYLIGNPETADNKFNSITMNFKEAITEEKAAQVEENVHL 360
Query: 361 IRFLRFLANFFVFLTLGGSGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFC 420
IRFLRFLANFFVFLTLGGSGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFC
Sbjct: 361 IRFLRFLANFFVFLTLGGSGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFC 420
Query: 421 PTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANIT 480
PTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANIT
Sbjct: 421 PTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANIT 480
Query: 481 LWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTIL 540
LWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTIL
Sbjct: 481 LWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTIL 540
Query: 541 IGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGI 600
IGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGI
Sbjct: 541 IGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGI 600
Query: 601 NILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPP 660
NILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPP
Sbjct: 601 NILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPP 660
Query: 661 SFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLAIYYLNATA 720
SFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLAIYYLNATA
Sbjct: 661 SFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLAIYYLNATA 720
Query: 721 KGQKAANLDLKKKMKMQALENKMRNKKMAAARAAAAAGRQ 760
KGQKAANLDLKKKMKMQALENKMRNKKMAAARAAAAAGRQ
Sbjct: 721 KGQKAANLDLKKKMKMQALENKMRNKKMAAARAAAAAGRQ 760
>gi|94536852 transmembrane cochlear-expressed protein 2 [Homo
sapiens]
Length = 906
Score = 893 bits (2307), Expect = 0.0
Identities = 439/757 (57%), Positives = 562/757 (74%), Gaps = 15/757 (1%)
Query: 2 SPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDE 61
SP++ Q +E E E E + +R+ ++RT E + P E
Sbjct: 68 SPRRKQTGRRRHREELGEQERGEAERTCEGRRKRDERASFQERTAAPKREKEI---PRRE 124
Query: 62 ETRKAREKERRRRLKRGAEE-EEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVL 120
E K ++K R L A E + EEEL ++ +++EK+++IAT++ KPW M KK+ L
Sbjct: 125 EKSKRQKKPRSSSLASSASGGESLSEEELAQILEQVEEKKKLIATMRSKPWPMAKKLTEL 184
Query: 121 KEAKKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQ 180
+EA++FV + EGALGKGKGK+ +A+KM+MAKKW KF RDF+NFK C+PWE KIK IES
Sbjct: 185 REAQEFVEKYEGALGKGKGKQLYAYKMLMAKKWVKFKRDFDNFKTQCIPWEMKIKDIESH 244
Query: 181 FGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANF 240
FGSSVASYF+FLRWMYGVN+VLF L F L+++PE L G+PYGS+PRKTVPRAEE A +F
Sbjct: 245 FGSSVASYFIFLRWMYGVNLVLFGLIFGLVIIPEVLMGMPYGSIPRKTVPRAEEEKAMDF 304
Query: 241 GVLYDFNGLAQYSVLFYGYYDNKRTIGWMNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNI 300
VL+DF G +YS LFYGYY+N+RTIGW+ +RLP++YF+VG+ GYS ++V+++M N
Sbjct: 305 SVLWDFEGYIKYSALFYGYYNNQRTIGWLRYRLPMAYFMVGVSVFGYSLIIVIRSMASNT 364
Query: 301 -GDDGGGDDNTFNFSWKVFTSWDYLIGNPETADNKFNSITMNFKEAITEEKAAQVEENVH 359
G G G+ + F FS+K+FTSWDYLIGN ETADNK+ SIT +FKE+I +E+ + EEN+H
Sbjct: 365 QGSTGEGESDNFTFSFKMFTSWDYLIGNSETADNKYASITTSFKESIVDEQESNKEENIH 424
Query: 360 LIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMF 419
L RFLR LANF + L GSGYLI++ VKRSQ+F++ + W+E+NE+ +VMSLLGMF
Sbjct: 425 LTRFLRVLANFLIICCLCGSGYLIYFVVKRSQQFSKMQ--NVSWYERNEVEIVMSLLGMF 482
Query: 420 CPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANI 479
CP LF+ A LE+YHP LKW LGRIFAL LGNLY F+LALMD+++ K+ E+ +K NI
Sbjct: 483 CPPLFETIAALENYHPRTGLKWQLGRIFALFLGNLYTFLLALMDDVHLKLANEETIK-NI 541
Query: 480 TLWEANMIKAYNAS-FSENSTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVT 538
T W + YN+S ++E+ PP +HPADVPRG CWET VG EF+RLTVSD+L TY+T
Sbjct: 542 THW--TLFNYYNSSGWNESVPRPP--LHPADVPRGSCWETAVGIEFMRLTVSDMLVTYIT 597
Query: 539 ILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLP 598
IL+GDFLRACFVRF NYCWCWDLE G+PSY EFDISGNVL LIFNQGMIWMGSF+AP L
Sbjct: 598 ILLGDFLRACFVRFMNYCWCWDLEAGFPSYAEFDISGNVLGLIFNQGMIWMGSFYAPGLV 657
Query: 599 GINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSL 658
GIN+LRL TSMYFQCWAVM NVP RVFKASRSNNFY+G+LLL+LFLS +PV Y I+SL
Sbjct: 658 GINVLRLLTSMYFQCWAVMSSNVPHERVFKASRSNNFYMGLLLLVLFLSLLPVAYTIMSL 717
Query: 659 PPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLAIYYLNA 718
PPSFDCGPFSGKNRM++V+ ET+E+DFP+++ KI L+NPGL+I IL+M LAIYYLN+
Sbjct: 718 PPSFDCGPFSGKNRMYDVLQETIENDFPTFLGKIFAFLANPGLIIPAILLMFLAIYYLNS 777
Query: 719 TAKGQKAANLDLKKKMKMQALENKMRNKKMAAARAAA 755
+K AN L+K K+Q L ++ K +A A
Sbjct: 778 VSKSLSRANAQLRK--KIQVLREVEKSHKSVKGKATA 812
>gi|122937502 transmembrane channel-like 3 [Homo sapiens]
Length = 1100
Score = 576 bits (1485), Expect = e-164
Identities = 289/704 (41%), Positives = 432/704 (61%), Gaps = 38/704 (5%)
Query: 81 EEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGK 140
+E D + E++ + ++ ++A ++C+PW M +K+ L++AK V + EG L + +G
Sbjct: 39 DETGDSNDPEQIFQNIQFQKDLMANIRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRG- 97
Query: 141 RWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNM 200
++ A+ W KF R NF +PWE +IK IES FGS VASYF+FLRW++G+N+
Sbjct: 98 ----YQAAGAELWRKFARLACNFVVIFIPWEMRIKKIESHFGSGVASYFIFLRWLFGINI 153
Query: 201 VLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYY 260
VL I+T + I++PE + G P+GS RKT+P+ + +SA + ++ G QYSVLFYGYY
Sbjct: 154 VLTIMTGAFIVIPELIAGQPFGSTARKTIPKEQVSSAQDLDTVWSLGGYLQYSVLFYGYY 213
Query: 261 DNKRTIGWMNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDD-GGGDDNTFNFSWKVFT 319
+R IG +RLPL+YFLVG+ YSF+++LK M KN + + F W+VF
Sbjct: 214 GRERKIGRAGYRLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFC 273
Query: 320 SWDYLIGNPETADNKFNSITMNFKEAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGS 379
+WDYLIGNPE A++K +I + +EAI EE+ + +N+ + LR +AN V L+L GS
Sbjct: 274 AWDYLIGNPEAAESKTAAIVNSIREAILEEQEKKKSKNLAVTICLRIIANILVLLSLAGS 333
Query: 380 GYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIAL 439
YLI++ V RSQ+ +Q L WEKNE+++V+SL+ M P+ FDL A LE YHP L
Sbjct: 334 IYLIYFVVDRSQKL-EQSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMYHPRTTL 392
Query: 440 KWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLW----------------- 482
++ L R+ L LGNLY I+AL+D++N+ EE K N + W
Sbjct: 393 RFQLARVLVLYLGNLYSLIIALLDKVNSMSIEEMATKNNTSHWIDSTTFFATRTAPEEEK 452
Query: 483 ----EANMIKAYNASFSENSTGPPFFVHP----------ADVPRGPCWETMVGQEFVRLT 528
M N +++ T + P P+ CWET VGQE ++L+
Sbjct: 453 WSTSRPGMGLRRNNTWALEETSISAYTMPLIKANKTSLHTQSPQDQCWETYVGQEMLKLS 512
Query: 529 VSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIW 588
+ D+L T +IL+ DF R FVR+ + WCWDLE +P Y EF I+ NVL L++NQGMIW
Sbjct: 513 IIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEFKIAENVLHLVYNQGMIW 572
Query: 589 MGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLST 648
MG+FF+P LP N+L+L MY + WAV+ CNVP +VF+ASRSNNFYL MLL +LFL
Sbjct: 573 MGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRSNNFYLAMLLFMLFLCM 632
Query: 649 MPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILV 708
+P ++ IV PS +CGPFSG+ ++++++ ET+E DFP W ++ +S+P +++ +L+
Sbjct: 633 LPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISSPVVILPAVLL 692
Query: 709 MVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMRNKKMAAAR 752
+ + IYYL + A+ K +N LK +++ E+K + +M AR
Sbjct: 693 LFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDKKKVAQMVEAR 736
>gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]
Length = 613
Score = 229 bits (584), Expect = 7e-60
Identities = 168/645 (26%), Positives = 292/645 (45%), Gaps = 77/645 (11%)
Query: 142 WFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMV 201
W +K +K W +FL W I++IE +FG+ + SYF FLR++ +N+V
Sbjct: 7 WDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLV 66
Query: 202 LFILTFSLIMLPEYLWGLPYGSLPRKTVP------RAEEASAANFGVLYDFN-------- 247
+F++ F L++LP L + +P + ++ G++Y ++
Sbjct: 67 IFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSG 126
Query: 248 -GLAQYSVLFYGYYDNKRTIGWMNFR-----LPLSYFLVGIMCIGYSFLVVLKAMTKNIG 301
G + + LFYG+Y TI + F+ LPL+Y L I + S L ++K +
Sbjct: 127 TGFLEETSLFYGHY----TIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFK 182
Query: 302 DDGGGDDNTF-NFSWKVFTSWDYLIGNPETADNKFNSITMNFKEAITEEK-----AAQVE 355
+ + F ++ K+F WD+ I N AD K +S+ + + EE+ A +
Sbjct: 183 INLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTS 242
Query: 356 ENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQEFAQQDPDTLGWWEKNEM----NM 411
E I LR N V LG Y I+ A SQE +++ D + + E + ++
Sbjct: 243 EETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSI 302
Query: 412 VMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEE 471
V++L P +F EDY P ++ + R + L + V + L +I + ++
Sbjct: 303 VITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDD 362
Query: 472 E-KLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWETMVGQEFVRLTVS 530
L N L+ PCWET VGQE +L +
Sbjct: 363 TCDLCGYNQKLY-------------------------------PCWETQVGQEMYKLMIF 391
Query: 531 DVLTTYVTILIGDFLRACFVRFCNYC---WCWDLEYGYPSYTEFDISGNVLALIFNQGMI 587
D + L DF R V +C+ C CW + EF I NVL +++ Q +
Sbjct: 392 DFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQ-------EFAIPDNVLGIVYGQTIC 444
Query: 588 WMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLS 647
W+G+FF+P LP I L+ Y + W+++ P R F+AS SN F+L +LL+ L L+
Sbjct: 445 WIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLA 504
Query: 648 TMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVIL 707
+P+ I +P S CGPF+ N +EVI +T+ FPS + + +++ + +
Sbjct: 505 IIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVS-TFPSSLQSFIHGVTSEAFAVPFFM 563
Query: 708 VMVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMRNKKMAAAR 752
++ L ++Y A A K + L++++ +++ + +K+ A+
Sbjct: 564 IICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLTEAQ 608
>gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]
Length = 723
Score = 229 bits (584), Expect = 7e-60
Identities = 168/645 (26%), Positives = 292/645 (45%), Gaps = 77/645 (11%)
Query: 142 WFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMV 201
W +K +K W +FL W I++IE +FG+ + SYF FLR++ +N+V
Sbjct: 117 WDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLV 176
Query: 202 LFILTFSLIMLPEYLWGLPYGSLPRKTVP------RAEEASAANFGVLYDFN-------- 247
+F++ F L++LP L + +P + ++ G++Y ++
Sbjct: 177 IFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSG 236
Query: 248 -GLAQYSVLFYGYYDNKRTIGWMNFR-----LPLSYFLVGIMCIGYSFLVVLKAMTKNIG 301
G + + LFYG+Y TI + F+ LPL+Y L I + S L ++K +
Sbjct: 237 TGFLEETSLFYGHY----TIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFK 292
Query: 302 DDGGGDDNTF-NFSWKVFTSWDYLIGNPETADNKFNSITMNFKEAITEEK-----AAQVE 355
+ + F ++ K+F WD+ I N AD K +S+ + + EE+ A +
Sbjct: 293 INLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTS 352
Query: 356 ENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQEFAQQDPDTLGWWEKNEM----NM 411
E I LR N V LG Y I+ A SQE +++ D + + E + ++
Sbjct: 353 EETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSI 412
Query: 412 VMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEE 471
V++L P +F EDY P ++ + R + L + V + L +I + ++
Sbjct: 413 VITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDD 472
Query: 472 E-KLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWETMVGQEFVRLTVS 530
L N L+ PCWET VGQE +L +
Sbjct: 473 TCDLCGYNQKLY-------------------------------PCWETQVGQEMYKLMIF 501
Query: 531 DVLTTYVTILIGDFLRACFVRFCNYC---WCWDLEYGYPSYTEFDISGNVLALIFNQGMI 587
D + L DF R V +C+ C CW + EF I NVL +++ Q +
Sbjct: 502 DFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQ-------EFAIPDNVLGIVYGQTIC 554
Query: 588 WMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLS 647
W+G+FF+P LP I L+ Y + W+++ P R F+AS SN F+L +LL+ L L+
Sbjct: 555 WIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLA 614
Query: 648 TMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVIL 707
+P+ I +P S CGPF+ N +EVI +T+ FPS + + +++ + +
Sbjct: 615 IIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVS-TFPSSLQSFIHGVTSEAFAVPFFM 673
Query: 708 VMVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMRNKKMAAAR 752
++ L ++Y A A K + L++++ +++ + +K+ A+
Sbjct: 674 IICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLTEAQ 718
>gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens]
Length = 706
Score = 176 bits (447), Expect = 6e-44
Identities = 169/671 (25%), Positives = 290/671 (43%), Gaps = 85/671 (12%)
Query: 110 PWKMEKKIEVLKEAKKFVSENEGALGKG-KGKRWFAFKMMMAKKWAKFLRDFENFKAACV 168
PW M+ + ++ S ++ G G K RW +K + LR +
Sbjct: 88 PWPMQAR---RAHRQRNASRDQVVYGSGTKTDRWARLLRRSKEKTKEGLRSLQ------- 137
Query: 169 PWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYG------ 222
PW +K I QFG+ SYF LR++ +N++ +L + +LP +L G P G
Sbjct: 138 PWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWLGGAPPGPPGPDI 197
Query: 223 SLPRKTVPRAEEASAANFGVLYDF---NGLAQYSVLFYGYYDNKRTIGWMNFRLPLSY-- 277
S P + + L++ G ++S LFYG+Y + RL ++Y
Sbjct: 198 SSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRP-------RLAVTYLC 250
Query: 278 --FLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTF-NFSWKVFTSWDY-LIGNPETADN 333
F VG++C+ L++L + + ++S +VF++WD+ L G+
Sbjct: 251 WAFAVGLICL----LLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLR 306
Query: 334 K---FNSITMNFKEAITEEKAA-QVEENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKR 389
+ + + +E + +AA + + +R L N V LG + Y ++WA
Sbjct: 307 QRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWATGC 366
Query: 390 SQEFAQ----QDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGR 445
+ E + Q+ L ++ ++ + P +F L A LE Y + ++L R
Sbjct: 367 TVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLR 426
Query: 446 IFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFV 505
L L +L V + +L ++I + E A K ++ +
Sbjct: 427 TVFLRLASLVVLLFSLWNQITCGGDSE-----------AEDCKTCGYNYKQL-------- 467
Query: 506 HPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGY 565
PCWET++GQE +L + D+LT L+ F R C G
Sbjct: 468 --------PCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGA------LGR 513
Query: 566 PSYT-EFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEA 624
+ T EF + VL LI+ Q ++W+GSFF P LP +N ++ Y + + P A
Sbjct: 514 LAGTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAA 573
Query: 625 RVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHD 684
R F+AS +N F+ +LLL L +S++P+LY I +PPS CGPF G++ ++ I E++
Sbjct: 574 RTFRASAANFFFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESIS-S 632
Query: 685 FPSWMAKILRQLSNPGLVIAVILVMVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMR 744
P L L + ++L+ + + Y A A +LK++ + +A +
Sbjct: 633 LPETTQNFLFFLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQTEA-----Q 687
Query: 745 NKKMAAARAAA 755
NK A RA A
Sbjct: 688 NKVFLARRAVA 698
>gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens]
Length = 712
Score = 176 bits (447), Expect = 6e-44
Identities = 169/671 (25%), Positives = 290/671 (43%), Gaps = 85/671 (12%)
Query: 110 PWKMEKKIEVLKEAKKFVSENEGALGKG-KGKRWFAFKMMMAKKWAKFLRDFENFKAACV 168
PW M+ + ++ S ++ G G K RW +K + LR +
Sbjct: 94 PWPMQAR---RAHRQRNASRDQVVYGSGTKTDRWARLLRRSKEKTKEGLRSLQ------- 143
Query: 169 PWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYG------ 222
PW +K I QFG+ SYF LR++ +N++ +L + +LP +L G P G
Sbjct: 144 PWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWLGGAPPGPPGPDI 203
Query: 223 SLPRKTVPRAEEASAANFGVLYDF---NGLAQYSVLFYGYYDNKRTIGWMNFRLPLSY-- 277
S P + + L++ G ++S LFYG+Y + RL ++Y
Sbjct: 204 SSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRP-------RLAVTYLC 256
Query: 278 --FLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTF-NFSWKVFTSWDY-LIGNPETADN 333
F VG++C+ L++L + + ++S +VF++WD+ L G+
Sbjct: 257 WAFAVGLICL----LLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLR 312
Query: 334 K---FNSITMNFKEAITEEKAA-QVEENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKR 389
+ + + +E + +AA + + +R L N V LG + Y ++WA
Sbjct: 313 QRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWATGC 372
Query: 390 SQEFAQ----QDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGR 445
+ E + Q+ L ++ ++ + P +F L A LE Y + ++L R
Sbjct: 373 TVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLR 432
Query: 446 IFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFV 505
L L +L V + +L ++I + E A K ++ +
Sbjct: 433 TVFLRLASLVVLLFSLWNQITCGGDSE-----------AEDCKTCGYNYKQL-------- 473
Query: 506 HPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGY 565
PCWET++GQE +L + D+LT L+ F R C G
Sbjct: 474 --------PCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGA------LGR 519
Query: 566 PSYT-EFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEA 624
+ T EF + VL LI+ Q ++W+GSFF P LP +N ++ Y + + P A
Sbjct: 520 LAGTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAA 579
Query: 625 RVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHD 684
R F+AS +N F+ +LLL L +S++P+LY I +PPS CGPF G++ ++ I E++
Sbjct: 580 RTFRASAANFFFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESIS-S 638
Query: 685 FPSWMAKILRQLSNPGLVIAVILVMVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMR 744
P L L + ++L+ + + Y A A +LK++ + +A +
Sbjct: 639 LPETTQNFLFFLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQTEA-----Q 693
Query: 745 NKKMAAARAAA 755
NK A RA A
Sbjct: 694 NKVFLARRAVA 704
>gi|23943900 transmembrane channel-like 8 [Homo sapiens]
Length = 726
Score = 152 bits (383), Expect = 1e-36
Identities = 152/589 (25%), Positives = 256/589 (43%), Gaps = 59/589 (10%)
Query: 170 WENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTV 229
WE + I FG+ + SYF FLR++ +N++ +LT S ++LP +W P P +
Sbjct: 91 WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLP-LVWLRPPDPGPTLNL 149
Query: 230 P-RAEEASAANFGVLYDFNGLAQY--------SVLFYGYYDNKRTIGWMNFRLPLSYFLV 280
+ + + GVL N L + LFYG Y + + + L+Y L
Sbjct: 150 TLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGPESSSV-YSIRLAYLLS 208
Query: 281 GIMCIGYSFLVVLKAMTKNIGDDGG-GDDNTFNFSWKVFTSWDYLIGNPETADNKFNSIT 339
+ C+ F L+ M K + G S KVF+SWD+ I E A K + I+
Sbjct: 209 PLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEIS 268
Query: 340 MNFKEAITEEKAAQVEEN-------VHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQE 392
FK + E + Q+ + L+ +LR N L + G+ IFWA K SQ+
Sbjct: 269 NEFKVELEEGRRFQLMQQQTRAQTACRLLSYLR--VNVLNGLLVVGAISAIFWATKYSQD 326
Query: 393 FAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLG 452
++ L + + +++ LG P LF +LE+Y P + L L L
Sbjct: 327 NKEESLFLLLQYLPPGVIALVNFLG---PLLFTFLVQLENYPPNTEVNLTLIWCVVLKLA 383
Query: 453 NLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPR 512
+L +F ++L T+ K+ S+ N V
Sbjct: 384 SLGMFSVSLGQ----------------TILCIGRDKSSCESYGYN------------VCD 415
Query: 513 GPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFV-RFCNYCWCWDLEYGYPSYTEF 571
CWE VG+E +L++ + L T + R V RF W W LE EF
Sbjct: 416 YQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAW-LER-----EEF 469
Query: 572 DISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASR 631
+ NVL ++ Q + WMG F+ P LP +N + L + Y + + ++ + +R F+AS
Sbjct: 470 LVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASS 529
Query: 632 SNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAK 691
S F+ +LLL L L+ +P+ Y++ S+ S+DCG F+ + ++V+ E + P +
Sbjct: 530 STFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQR 589
Query: 692 ILRQLSNPGLVIAVILVMVLAIYYLNATAKGQKAANLDLKKKMKMQALE 740
L L + +++++ L + + + A L+K++ Q E
Sbjct: 590 ALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQE 638
>gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens]
Length = 1006
Score = 138 bits (347), Expect = 2e-32
Identities = 130/563 (23%), Positives = 242/563 (42%), Gaps = 88/563 (15%)
Query: 170 WENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTV 229
W+ +K I +FG+SV SYF FLRW+ N+ FIL FS I++P++
Sbjct: 431 WQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQFT------------- 477
Query: 230 PRAEEASAANFGVLYDFNGLAQY--SVLFYGYYDNKRTIGWMN----FRLPLSYFLVGIM 283
+ + F L F G+ + +V++YG+Y N TI N + + L+Y
Sbjct: 478 --VAKKNTLQFTGLEFFTGVGYFRDTVMYYGFYTNS-TIQHGNSGASYNMQLAYIFTIGA 534
Query: 284 CIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFTSWDYLIGNPETADNKFNSITMNFK 343
C+ F +L +M K ++ K+ WD+ + + + K +++ +
Sbjct: 535 CLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKLKQKNLSTEIR 594
Query: 344 EAITE--EKAAQVEENVHLIRFLRFLANFFVFLTLG-GSGYLIFWAVKRSQEFAQ--QDP 398
E ++E ++ +++ N L RF ++ + V + +++ + + EF + +P
Sbjct: 595 ENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNP 654
Query: 399 DTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFI 458
+ + V+S + + P ++ +F +E Y + ++ LL+ N+++ I
Sbjct: 655 GAVLL-----LPFVVSCINLAVPCIYSMFRLVERY------EMPRHEVYVLLIRNIFLKI 703
Query: 459 LALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWET 518
+ I Y ++++ + CWET
Sbjct: 704 SIIG------------------------ILCY------------YWLNTVALSGEECWET 727
Query: 519 MVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVL 578
++GQ+ RL + D + + V +G+FLR R L EFDI+ NVL
Sbjct: 728 LIGQDIYRLLLMDFVFSLVNSFLGEFLR----RIIGMQLITSL-----GLQEFDIARNVL 778
Query: 579 ALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLG 638
LI+ Q ++W+G FF P LP I ++ L Y + ++M P ++ ++AS+ F++
Sbjct: 779 ELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIF 838
Query: 639 MLLLILFLSTMPVLYMIV-SLPPSFDCGPFSGK----NRMFEVIGETLEHDFPSWMAKIL 693
+L F + L + + L PS DCGPF G + ++ I W+ I
Sbjct: 839 LLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWVVWIY 898
Query: 694 RQLSNPGLVIAVILVMVLAIYYL 716
R L ++ ++VL I YL
Sbjct: 899 RNLIGSVHFFFILTLIVLIITYL 921
>gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens]
Length = 760
Score = 138 bits (347), Expect = 2e-32
Identities = 130/563 (23%), Positives = 242/563 (42%), Gaps = 88/563 (15%)
Query: 170 WENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTV 229
W+ +K I +FG+SV SYF FLRW+ N+ FIL FS I++P++
Sbjct: 185 WQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQFT------------- 231
Query: 230 PRAEEASAANFGVLYDFNGLAQY--SVLFYGYYDNKRTIGWMN----FRLPLSYFLVGIM 283
+ + F L F G+ + +V++YG+Y N TI N + + L+Y
Sbjct: 232 --VAKKNTLQFTGLEFFTGVGYFRDTVMYYGFYTNS-TIQHGNSGASYNMQLAYIFTIGA 288
Query: 284 CIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFTSWDYLIGNPETADNKFNSITMNFK 343
C+ F +L +M K ++ K+ WD+ + + + K +++ +
Sbjct: 289 CLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKLKQKNLSTEIR 348
Query: 344 EAITE--EKAAQVEENVHLIRFLRFLANFFVFLTLG-GSGYLIFWAVKRSQEFAQ--QDP 398
E ++E ++ +++ N L RF ++ + V + +++ + + EF + +P
Sbjct: 349 ENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNP 408
Query: 399 DTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFI 458
+ + V+S + + P ++ +F +E Y + ++ LL+ N+++ I
Sbjct: 409 GAVLL-----LPFVVSCINLAVPCIYSMFRLVERY------EMPRHEVYVLLIRNIFLKI 457
Query: 459 LALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWET 518
+ I Y ++++ + CWET
Sbjct: 458 SIIG------------------------ILCY------------YWLNTVALSGEECWET 481
Query: 519 MVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVL 578
++GQ+ RL + D + + V +G+FLR R L EFDI+ NVL
Sbjct: 482 LIGQDIYRLLLMDFVFSLVNSFLGEFLR----RIIGMQLITSL-----GLQEFDIARNVL 532
Query: 579 ALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLG 638
LI+ Q ++W+G FF P LP I ++ L Y + ++M P ++ ++AS+ F++
Sbjct: 533 ELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIF 592
Query: 639 MLLLILFLSTMPVLYMIV-SLPPSFDCGPFSGK----NRMFEVIGETLEHDFPSWMAKIL 693
+L F + L + + L PS DCGPF G + ++ I W+ I
Sbjct: 593 LLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWVVWIY 652
Query: 694 RQLSNPGLVIAVILVMVLAIYYL 716
R L ++ ++VL I YL
Sbjct: 653 RNLIGSVHFFFILTLIVLIITYL 675
>gi|187608784 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 134 bits (337), Expect = 3e-31
Identities = 146/598 (24%), Positives = 243/598 (40%), Gaps = 95/598 (15%)
Query: 166 ACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLP 225
A +PW +K I QFGSSV SYFLFL+ + N +L +L + IM P+ + P P
Sbjct: 226 ALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFP-PALPGP 284
Query: 226 RKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRT----------------IGWM 269
E + A G ++V++YG+Y N +G +
Sbjct: 285 APVCTGLELLTGA---------GCFTHTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGL 335
Query: 270 NFRLPLSYFLVGIMCIGYSFLV----VLKAMTKNIGDDGGGDDNTFNFSWKVFTSWDYLI 325
+ +PL+Y + +G SF + ++ +M + G+ + + VF SWDY +
Sbjct: 336 PYNMPLAY----LSTVGVSFFITCITLVYSMAHSFGESYRVGSTSGIHAITVFCSWDYKV 391
Query: 326 GNPETADNKFNSITMNFKEAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFW 385
+ + ++I KE + E + +V R + V+L G+
Sbjct: 392 TQKRASRLQQDNIRTRLKELLAEWQLRHSPRSV-CGRLRQAAVLGLVWLLCLGTALGCAV 450
Query: 386 AVKRSQEFAQQDPDTLGWWEKN-EMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLG 444
AV EF Q P+ G + +V+ LL + P L + A LE + +
Sbjct: 451 AVHVFSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAALEPHDSPVL------ 504
Query: 445 RIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFF 504
++ + NL + LA++ + W +
Sbjct: 505 EVYVAICRNL-ILKLAILGTLCYH-------------WLGRRV----------------- 533
Query: 505 VHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYG 564
V +G CWE VGQE R V D + + L G+ + + +
Sbjct: 534 ----GVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIIS---------EKKLK 580
Query: 565 YPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMC-CNVPE 623
EFDI+ NVL LI+ Q + W+G F+P LP + I++L Y + +++ C P
Sbjct: 581 RRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPR 640
Query: 624 ARVFKASRSNNFYLGMLLLILFLSTMPVL-YMIVSLPPSFDCGPFSGKNRMFE---VIGE 679
R + AS + +L +L FL L Y + + PS CGPF + M+E V
Sbjct: 641 -RPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVR 699
Query: 680 TLEHDFP--SWMAKILRQLSNPGLVIAVILVMVLAIYYLN-ATAKGQKAANLDLKKKM 734
LE P SW+ + R L + ++ ++LA+ YLN +GQ+ LK+++
Sbjct: 700 HLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQI 757
>gi|187608791 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 134 bits (337), Expect = 3e-31
Identities = 146/598 (24%), Positives = 243/598 (40%), Gaps = 95/598 (15%)
Query: 166 ACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLP 225
A +PW +K I QFGSSV SYFLFL+ + N +L +L + IM P+ + P P
Sbjct: 226 ALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFP-PALPGP 284
Query: 226 RKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRT----------------IGWM 269
E + A G ++V++YG+Y N +G +
Sbjct: 285 APVCTGLELLTGA---------GCFTHTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGL 335
Query: 270 NFRLPLSYFLVGIMCIGYSFLV----VLKAMTKNIGDDGGGDDNTFNFSWKVFTSWDYLI 325
+ +PL+Y + +G SF + ++ +M + G+ + + VF SWDY +
Sbjct: 336 PYNMPLAY----LSTVGVSFFITCITLVYSMAHSFGESYRVGSTSGIHAITVFCSWDYKV 391
Query: 326 GNPETADNKFNSITMNFKEAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFW 385
+ + ++I KE + E + +V R + V+L G+
Sbjct: 392 TQKRASRLQQDNIRTRLKELLAEWQLRHSPRSV-CGRLRQAAVLGLVWLLCLGTALGCAV 450
Query: 386 AVKRSQEFAQQDPDTLGWWEKN-EMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLG 444
AV EF Q P+ G + +V+ LL + P L + A LE + +
Sbjct: 451 AVHVFSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAALEPHDSPVL------ 504
Query: 445 RIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFF 504
++ + NL + LA++ + W +
Sbjct: 505 EVYVAICRNL-ILKLAILGTLCYH-------------WLGRRV----------------- 533
Query: 505 VHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYG 564
V +G CWE VGQE R V D + + L G+ + + +
Sbjct: 534 ----GVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIIS---------EKKLK 580
Query: 565 YPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMC-CNVPE 623
EFDI+ NVL LI+ Q + W+G F+P LP + I++L Y + +++ C P
Sbjct: 581 RRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPR 640
Query: 624 ARVFKASRSNNFYLGMLLLILFLSTMPVL-YMIVSLPPSFDCGPFSGKNRMFE---VIGE 679
R + AS + +L +L FL L Y + + PS CGPF + M+E V
Sbjct: 641 -RPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVR 699
Query: 680 TLEHDFP--SWMAKILRQLSNPGLVIAVILVMVLAIYYLN-ATAKGQKAANLDLKKKM 734
LE P SW+ + R L + ++ ++LA+ YLN +GQ+ LK+++
Sbjct: 700 HLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQI 757
>gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens]
Length = 948
Score = 120 bits (301), Expect = 5e-27
Identities = 111/498 (22%), Positives = 215/498 (43%), Gaps = 83/498 (16%)
Query: 170 WENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTV 229
W+ +K I +FG+SV SYF FLRW+ N+ FIL FS I++P++
Sbjct: 431 WQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQFT------------- 477
Query: 230 PRAEEASAANFGVLYDFNGLAQY--SVLFYGYYDNKRTIGWMN----FRLPLSYFLVGIM 283
+ + F L F G+ + +V++YG+Y N TI N + + L+Y
Sbjct: 478 --VAKKNTLQFTGLEFFTGVGYFRDTVMYYGFYTNS-TIQHGNSGASYNMQLAYIFTIGA 534
Query: 284 CIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFTSWDYLIGNPETADNKFNSITMNFK 343
C+ F +L +M K ++ K+ WD+ + + + K +++ +
Sbjct: 535 CLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKLKQKNLSTEIR 594
Query: 344 EAITE--EKAAQVEENVHLIRFLRFLANFFVFLTLG-GSGYLIFWAVKRSQEFAQ--QDP 398
E ++E ++ +++ N L RF ++ + V + +++ + + EF + +P
Sbjct: 595 ENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNP 654
Query: 399 DTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFI 458
+ + V+S + + P ++ +F +E Y + ++ LL+ N+++ I
Sbjct: 655 GAVLL-----LPFVVSCINLAVPCIYSMFRLVERY------EMPRHEVYVLLIRNIFLKI 703
Query: 459 LALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWET 518
+ I Y ++++ + CWET
Sbjct: 704 SIIG------------------------ILCY------------YWLNTVALSGEECWET 727
Query: 519 MVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVL 578
++GQ+ RL + D + + V +G+FLR R L EFDI+ NVL
Sbjct: 728 LIGQDIYRLLLMDFVFSLVNSFLGEFLR----RIIGMQLITSL-----GLQEFDIARNVL 778
Query: 579 ALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLG 638
LI+ Q ++W+G FF P LP I ++ L Y + ++M P ++ ++AS+ F++
Sbjct: 779 ELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIF 838
Query: 639 MLLLILFLSTMPVLYMIV 656
+L F + L + +
Sbjct: 839 LLFFPSFTGVLCTLAITI 856
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 63.5 bits (153), Expect = 7e-10
Identities = 39/122 (31%), Positives = 69/122 (56%), Gaps = 2/122 (1%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEET 63
KK + K E+ +ETEE+ EEE+E + K R+E + K K+ + E + E E+EE
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKT--KETEKRKEKEEEEK 60
Query: 64 RKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEA 123
++ R++++++ + EEEE +EEE E + E +R+ + K + EKK + ++
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Query: 124 KK 125
KK
Sbjct: 121 KK 122
Score = 52.8 bits (125), Expect = 1e-06
Identities = 31/98 (31%), Positives = 54/98 (55%), Gaps = 7/98 (7%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEET 63
+K + K +EK+ +T+E+ +E+E E+K + KRKR + E+ E E E+EE
Sbjct: 33 RKEKRKEKEKKKKTKETEKRKEKEEEEK-------KRKRKRKKKKEEEEREEEEEEEEEE 85
Query: 64 RKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
++ EKE RR K+ + +EEE ++ K K++
Sbjct: 86 KEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/103 (25%), Positives = 54/103 (52%)
Query: 39 RPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDE 98
+ K+K+ ++ ++ E E+EE R+++R+ + K ++++ E E + K E ++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 99 KRQIIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKR 141
KR+ K + + E++ E +E K+ + EG K K KR
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR 103
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 57.8 bits (138), Expect = 4e-08
Identities = 38/128 (29%), Positives = 72/128 (56%), Gaps = 21/128 (16%)
Query: 5 KVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDE-ET 63
K + + E E+EE SEE E + D+L ++ESL +E++ E E E+E E
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLS----------SEEEEEREEEEEREE 2259
Query: 64 RKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEA 123
+ RE+E R+ + EE+++++EE E+ K + ++K++ ++++K EV +E
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKE----------EVQEKEEVFEEK 2309
Query: 124 KKFVSENE 131
++ +SE E
Sbjct: 2310 EEIMSEEE 2317
Score = 50.8 bits (120), Expect = 5e-06
Identities = 31/128 (24%), Positives = 69/128 (53%), Gaps = 10/128 (7%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEET 63
++++ ++E E + SS EEEE E++ E +R + + ++ ++ + E E+EE
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK 2287
Query: 64 RKAREKERRRRLKRGAE-----EEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIE 118
+K ++++++ ++ E EE + EEE E L E +E+ +++++ E
Sbjct: 2288 KKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEE-----EVDREKE 2342
Query: 119 VLKEAKKF 126
+LK+ K+F
Sbjct: 2343 ILKKEKQF 2350
Score = 47.8 bits (112), Expect = 4e-05
Identities = 44/185 (23%), Positives = 80/185 (43%), Gaps = 21/185 (11%)
Query: 1 MSPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPED 60
+S ++ + + EE+E E EE EEEE E++ + + + + + E E E
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK 2302
Query: 61 EETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVL 120
EE + +E+ +EE +EEE L+ E+D +++I+ K EK+ ++
Sbjct: 2303 EEVFEEKEEIMSEEETESLSDEE-EEEESCSLEEEVDREKEIL--------KKEKQFKLQ 2353
Query: 121 KEAKKFVSENEGAL--------GKGKGKRWFAFKMMMAKKWAKFLRDFENFKAAC----V 168
++ +K + E L GKG+ R K + K + L E +
Sbjct: 2354 EQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQI 2413
Query: 169 PWENK 173
WE+K
Sbjct: 2414 SWEDK 2418
Score = 38.9 bits (89), Expect = 0.018
Identities = 47/176 (26%), Positives = 78/176 (44%), Gaps = 12/176 (6%)
Query: 16 ETEESSSEEEEEVEDKLPRR-----ESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
+ EE EEEEV L RR E+ R + + + D+ E E E ++ E
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE 2236
Query: 71 RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSEN 130
++ +EEEE EEE ER + E+ E+ + + K +K E K+ KK +
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKK 2296
Query: 131 EGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAAC-----VPWENKIKAIESQF 181
E + K + + + +M+++ + L D E + +C V E +I E QF
Sbjct: 2297 EEV--QEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQF 2350
Score = 38.1 bits (87), Expect = 0.031
Identities = 38/158 (24%), Positives = 71/158 (44%), Gaps = 14/158 (8%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEET 63
K+ Q K EE+ EE S E EE+ + + ++ + K R E + EE
Sbjct: 1534 KEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEER 1593
Query: 64 RKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEA 123
+ A+E+E+ + +R +E E +L + ++ + + +A + K +K E L +
Sbjct: 1594 KLAQEEEKLAQEERQLAQE---ERKLAQAYVKITQDDREMAQAE---GKFAQKEETLAQR 1647
Query: 124 KKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFE 161
+ +S+ L + + K +AKKW K R+ E
Sbjct: 1648 GEKLSQEAEKLAQKRKK--------LAKKWEKVAREEE 1677
Score = 35.0 bits (79), Expect = 0.26
Identities = 41/147 (27%), Positives = 75/147 (51%), Gaps = 16/147 (10%)
Query: 4 KKVQIKVEEKEDETEESSSEEEE--EVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDE 61
K++ ++EE E + EE S +EEE + E KL + K+K + + +E
Sbjct: 1712 KELAQELEELEWDMEELSWKEEELNQEEGKL-----VEEKKKLAEEEEALAWQREKLSEE 1766
Query: 62 ETRKAREKE----RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPW--KMEK 115
ET+ A+E+E + +L + E+ +EE L R + +L EK+ +A K + W ME+
Sbjct: 1767 ETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQ-KRERWINSMEE 1825
Query: 116 --KIEVLKEAKKFVSENEGALGKGKGK 140
K +++ KK +++ + L + K K
Sbjct: 1826 LTKNKMILYQKKNLAQEKKNLAQEKEK 1852
Score = 33.1 bits (74), Expect = 0.99
Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 8/128 (6%)
Query: 7 QIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKA 66
Q K++ KE + E SE ++ E KL R++ R + R +IN+++ E E + RK
Sbjct: 2115 QSKLDIKEWDFSEKRSELTKD-EKKLARKQ--RKLANKMRRMINKEEKMTEEESKLARKH 2171
Query: 67 REKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKF 126
E + G EEEE+ + LK ++++ K K K +++ ++ + F
Sbjct: 2172 SEVILDDEEEGGIEEEEV----IPFLKRRWRKRKEAKRGDKPKE-KFSSQVDEVESEEHF 2226
Query: 127 VSENEGAL 134
E E L
Sbjct: 2227 SEEMESLL 2234
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 53.9 bits (128), Expect = 5e-07
Identities = 46/126 (36%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 7 QIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKA 66
+I+ E+E ET + +E E E K RRE R KRKR R E + + E +E +
Sbjct: 37 EIREREREIETRKEGKKERES-ERKKERRE--REKRKRER----EKERKRERGKKEKKGE 89
Query: 67 REKERRRRLKRGAEEEEIDEEELE-RLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKK 125
R+KE R R KR E+E + EE E R K E E+ + K + K E+K E KE ++
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
Query: 126 FVSENE 131
E E
Sbjct: 150 KKEERE 155
Score = 50.4 bits (119), Expect = 6e-06
Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 7/129 (5%)
Query: 4 KKVQIKVEEKED-----ETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEP 58
KK + K EE+E E E EE+E+ + K + K + R+ E E
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
Query: 59 EDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDE--KRQIIATVKCKPWKMEKK 116
E E ++ REKER R+ ++ E +++ E+E ER + E E KR+ + K + +++
Sbjct: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205
Query: 117 IEVLKEAKK 125
E KE KK
Sbjct: 206 RERKKERKK 214
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/129 (29%), Positives = 67/129 (51%), Gaps = 12/129 (9%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEET 63
KK + + E+++ E E+ E + E K R++ R ++KR R+ N+ E E++E
Sbjct: 60 KKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENK-----EGEEKEK 114
Query: 64 RKAREKERRRRLKRGAEEEEIDEE-------ELERLKAELDEKRQIIATVKCKPWKMEKK 116
RK +EK+ R R + +E E EE E ER K E +++R+ K + ++ +K
Sbjct: 115 RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK 174
Query: 117 IEVLKEAKK 125
E KE ++
Sbjct: 175 EEERKEKER 183
Score = 49.3 bits (116), Expect = 1e-05
Identities = 26/91 (28%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
E KE+ E E E + E++ RE + ++KR R + E + E + ++ + RK RE+
Sbjct: 134 ERKEERKREERKERERKKEEREKERER-KERKKRERKQVGEKEEERKEKERKERKKRERN 192
Query: 71 RRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
R+ R K +E + ++ + K E ++RQ
Sbjct: 193 RKERKKERERKERRERKKERKKKEERKKERQ 223
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Query: 12 EKEDETEESSSEEEEEVEDKLP-RRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EKE E +E E ++V +K R+E R +RK+ E E E ++ RK K+
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 71 RRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
+ R K ++ + + E ER K E E+++
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 40.4 bits (93), Expect = 0.006
Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEE---TRK 65
K ++ + EE EE +E E K RE R +++R + E E E+E RK
Sbjct: 128 KEGKERERKEERKREERKERERKKEEREKERERKERKK---RERKQVGEKEEERKEKERK 184
Query: 66 AREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWK-MEKKIEVLKEAK 124
R+K R R +R E E + E ++ + + +E+++ + W+ E+ KE K
Sbjct: 185 ERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
Query: 125 K 125
K
Sbjct: 245 K 245
Score = 40.0 bits (92), Expect = 0.008
Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 12/136 (8%)
Query: 11 EEKEDETEES----SSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKA 66
+EK + E+ +S+E +E E K R+ R +R+R ++ ++ E + E ++
Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171
Query: 67 REKERRRRLKRGAEEEEIDEEELERLK-AELDEKRQIIATVKCKPWKMEKKIEVLKEAKK 125
EKE R+ K E ++ + ER K E E+R+ + + +KK E KE +K
Sbjct: 172 GEKEEERKEKERKERKKRERNRKERKKERERKERRE-------RKKERKKKEERKKERQK 224
Query: 126 FVSENEGALGKGKGKR 141
N +GK +R
Sbjct: 225 DRQTNWREKERGKRER 240
Score = 38.5 bits (88), Expect = 0.023
Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 9/132 (6%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
++E +++ +E SE ++E ++ R+ +RKR R + + E E ++ RE
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103
Query: 69 KERR------RRLKRGAEEE---EIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEV 119
KE + +R K+ +E + +E ER + E+R+ K + K ++ E
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKER 163
Query: 120 LKEAKKFVSENE 131
K +K V E E
Sbjct: 164 KKRERKQVGEKE 175
Score = 33.5 bits (75), Expect = 0.75
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Query: 42 RKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
R+R R++ + + E E E R+KERR R KR E E+ + E + + + + K++
Sbjct: 39 REREREIETRKEGKKERESE-----RKKERREREKRKREREKERKRERGKKEKKGERKKE 93
Query: 102 IIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGK 136
K + K K+ E ++ KK + G K
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSK 128
Score = 33.5 bits (75), Expect = 0.75
Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 11/91 (12%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEET 63
K+ + +V EKE+E +E +E + +RE R +RK+ R+ + + E + +E
Sbjct: 165 KRERKQVGEKEEERKEKERKERK-------KRERNRKERKKERERKERRERKKERKKKEE 217
Query: 64 RKAREKERRR-RLKRGAEEEEIDEEELERLK 93
RK KER++ R E+E E ER K
Sbjct: 218 RK---KERQKDRQTNWREKERGKRERKERKK 245
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 53.5 bits (127), Expect = 7e-07
Identities = 45/146 (30%), Positives = 74/146 (50%), Gaps = 32/146 (21%)
Query: 11 EEKEDETEESSSEEEEEV---EDKLPRRESL----RPKRKRTRDVINEDDP---EPEPED 60
EEK E EE E+EE++ E+K+ R+E + K +R +++ E + E E +
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 61 EETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKI--- 117
E K RE+E +R+ EEE+I E+ EKRQ + K W+ E+KI
Sbjct: 354 HEQEKIREQEEKRQ-----EEEKIREQ----------EKRQ---EQEAKMWRQEEKIREQ 395
Query: 118 -EVLKEAKKFVSENEGALGKGKGKRW 142
E ++E ++ + E E +G+ + K W
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMW 421
Score = 51.2 bits (121), Expect = 3e-06
Identities = 30/137 (21%), Positives = 74/137 (54%), Gaps = 1/137 (0%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEET 63
++++ K+ E+E E+ +EEE + +R+ K R + I E + + ++E
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM 406
Query: 64 RKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEA 123
++ EK + K +EEE+ E+E E+++ + ++ R+ ++ + K+ ++ E+++E
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQE-EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Query: 124 KKFVSENEGALGKGKGK 140
++ + E EG + + + K
Sbjct: 466 EEKMGEQEGKMCEQEAK 482
Score = 50.8 bits (120), Expect = 5e-06
Identities = 34/134 (25%), Positives = 71/134 (52%), Gaps = 5/134 (3%)
Query: 11 EEKEDETEESSSEEEE--EVEDKLPRRESLRPKRKRTRDVIN--EDDPEPEPEDEETRKA 66
EEK E EE E+E+ E E+K E +R + KR + + ++E+ R+
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402
Query: 67 REKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKF 126
E + + K G +EE++ E+E E ++ + ++ R+ ++ + K+ ++ E ++E ++
Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQE-EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461
Query: 127 VSENEGALGKGKGK 140
+ E E +G+ +GK
Sbjct: 462 MQEQEEKMGEQEGK 475
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 8/132 (6%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EE E EE E+EE++ ++ + K +R + I E + + ++E+ R+ E
Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462
Query: 71 RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSEN 130
+ + K G +E ++ E+E A++ E+ + + + K + EKKI +E ++ + E
Sbjct: 463 QEQEEKMGEQEGKMCEQE-----AKMQEQEEKMRRQEEKIREQEKKI---REQEEKIREQ 514
Query: 131 EGALGKGKGKRW 142
E + + + K W
Sbjct: 515 EEMMQEQEEKMW 526
Score = 44.3 bits (103), Expect = 4e-04
Identities = 29/121 (23%), Positives = 66/121 (54%), Gaps = 1/121 (0%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EEK E EE E+EE ++++ + K + + E + + ++E+ R+ +EK+
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE-QEKK 447
Query: 71 RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSEN 130
R + ++ E+EE+ +E+ E++ + + + A ++ + KM ++ E ++E +K + E
Sbjct: 448 IREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507
Query: 131 E 131
E
Sbjct: 508 E 508
Score = 38.9 bits (89), Expect = 0.018
Identities = 22/91 (24%), Positives = 46/91 (50%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EE E EE E+E ++ ++ + + K +R + I E + + ++E+ R+ E
Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Query: 71 RRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
+ + K +EE++ E+E + + E +RQ
Sbjct: 519 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 549
Score = 37.7 bits (86), Expect = 0.040
Identities = 28/109 (25%), Positives = 59/109 (54%), Gaps = 9/109 (8%)
Query: 11 EEKEDETEESSSEEE---EEVEDKLPRRES-LRPKRKRTRDVINEDDPEPEPEDEETRKA 66
EEK E E E+E +E E+K+ R+E +R + K+ R+ E E EE +
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE-----QEEKIREQEEMMQE 520
Query: 67 REKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEK 115
+E++ + ++ E+EE +E+ E+++ + ++ R+ ++ + KM++
Sbjct: 521 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 37.0 bits (84), Expect = 0.068
Identities = 26/127 (20%), Positives = 63/127 (49%), Gaps = 6/127 (4%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EEK E E+ E+EE++ ++ + K + E + + + ++E+ R+ EK
Sbjct: 438 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKI 497
Query: 71 RRRRLK------RGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAK 124
R + K + E+EE+ +E+ E++ + ++ + ++ + KM ++ E ++E +
Sbjct: 498 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Query: 125 KFVSENE 131
+ + E
Sbjct: 558 VRLRQQE 564
Score = 34.3 bits (77), Expect = 0.44
Identities = 20/120 (16%), Positives = 63/120 (52%), Gaps = 3/120 (2%)
Query: 1 MSPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPED 60
M ++ ++ +E+E + +E +EE + ++ + ++ R ++ + ++ E E
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472
Query: 61 EE---TRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKI 117
E ++A+ +E+ +++R E+ E+++ + ++ E+ +++ + K W+ E+K+
Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 532
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 52.4 bits (124), Expect = 2e-06
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 18/137 (13%)
Query: 11 EEKEDETEESSSEEEE--EVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
EEK E EE E+E+ E E+K E +R + KR E + + ++E+ R+ E
Sbjct: 437 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR-----QEQEAKMWRQEEKIREQEE 491
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKI---EVLKEAKK 125
K R + K +EE+I E+E K +EKRQ + + W+ E+KI E + K+
Sbjct: 492 KIREQEEKMWRQEEKIHEQE----KIREEEKRQ----EQEEMWRQEEKIREQEEIWRQKE 543
Query: 126 FVSENEGALGKGKGKRW 142
+ E E + K + K W
Sbjct: 544 KIHEQEEKIRKQEEKMW 560
Score = 47.8 bits (112), Expect = 4e-05
Identities = 34/137 (24%), Positives = 71/137 (51%), Gaps = 7/137 (5%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EEK E EE E+EE++ ++ + K +R +++ E + + ++E + EK
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
Query: 71 RRRRLKRGAEEEEIDE-----EELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKK 125
RR+ +EE+I E E E+++ E +EKRQ ++ + + E++ ++ ++ +K
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIR-EQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 485
Query: 126 FVSENEGALGKGKGKRW 142
+ E E + + + K W
Sbjct: 486 -IREQEEKIREQEEKMW 501
Score = 47.4 bits (111), Expect = 5e-05
Identities = 31/131 (23%), Positives = 66/131 (50%), Gaps = 12/131 (9%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDE-- 61
++++ K+ E+E E+ +EEE + +R+ K R + I E + + ++E
Sbjct: 441 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500
Query: 62 --ETRKAREKERRRRLKRGAEEEEI--------DEEELERLKAELDEKRQIIATVKCKPW 111
+ K E+E+ R ++ E+EE+ ++EE+ R K ++ E+ + I + K W
Sbjct: 501 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560
Query: 112 KMEKKIEVLKE 122
+ E+K+ +E
Sbjct: 561 RQEEKMHDQEE 571
Score = 47.0 bits (110), Expect = 7e-05
Identities = 28/121 (23%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EEK + EE +EE++ D+ + K R + I E + + ++E+ R+ E
Sbjct: 549 EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMT 608
Query: 71 RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSEN 130
+ + K G +EE++ E+E E+++ + ++ R+ ++ + K+ ++ E ++E ++ + E
Sbjct: 609 QEQEEKMGEQEEKMCEQE-EKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 667
Query: 131 E 131
E
Sbjct: 668 E 668
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 15/132 (11%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EEK E EE E+EE++ ++ + K + + E + + + ++E+ R+ EK
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 71 RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSEN 130
R + K +EE+I E+ E + E +EK W+ E+K + E ++ + E
Sbjct: 644 REQEKKIREQEEKIREQ--EEMMQEQEEKM----------WEQEEK---MCEQEEKMQEQ 688
Query: 131 EGALGKGKGKRW 142
E + + + K W
Sbjct: 689 EEKMRRQEEKMW 700
Score = 45.8 bits (107), Expect = 1e-04
Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 16/137 (11%)
Query: 11 EEKEDETEESSSEEEE---EVEDKLPRRESL----RPKRKRTRDVINEDDP---EPEPED 60
EEK E EE +EE E E+K+ R+E + K +R +++ E + E E +
Sbjct: 388 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 447
Query: 61 EETRKAREKERRRRLKRGAEEEEIDEEE---LERLKAELDEKRQIIATVKCKPWKMEKKI 117
E K RE+E +R+ + E+E +E+ + R + ++ E+ + I + K W+ E+KI
Sbjct: 448 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507
Query: 118 ---EVLKEAKKFVSENE 131
E ++E +K + E
Sbjct: 508 HEQEKIREEEKRQEQEE 524
Score = 43.9 bits (102), Expect = 6e-04
Identities = 27/112 (24%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EE E EE E+EE++ ++ + + K +R + I E + + ++E+ R+ E
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664
Query: 71 RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKE 122
+ + K +EE++ E+E + + E +RQ + K W+ E ++ +E
Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ-----EEKMWEQEVRLRQQEE 711
Score = 43.5 bits (101), Expect = 7e-04
Identities = 33/142 (23%), Positives = 76/142 (53%), Gaps = 8/142 (5%)
Query: 4 KKVQIKVEEKEDETEESSSEEEE--EVEDKLPRRESL---RPKRKRTRDVINEDDPEPEP 58
+K+Q E+ +++ E+ +EE+ E E+K+ R+E + + ++ R ++ + + E
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 427
Query: 59 EDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIE 118
EE +E++ R ++ E+E+I E+E +R + E +++ + K W+ E+KI
Sbjct: 428 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI- 486
Query: 119 VLKEAKKFVSENEGALGKGKGK 140
+E ++ + E E + + + K
Sbjct: 487 --REQEEKIREQEEKMWRQEEK 506
Score = 42.0 bits (97), Expect = 0.002
Identities = 36/138 (26%), Positives = 71/138 (51%), Gaps = 18/138 (13%)
Query: 11 EEKEDETEESSSEEEEEV---EDKLPRRESLRPKRKRTR--------DVINEDDP----- 54
EEK E EE E+EE++ E+K+ +E +R + KR + I E +
Sbjct: 483 EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 542
Query: 55 -EPEPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKM 113
+ ++E+ RK EK R+ K +EE+I E+E E++ + ++ R+ ++ + K+
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE-EKVWRQEEKIREQEEKIREQEEKI 601
Query: 114 EKKIEVLKEAKKFVSENE 131
++ E+ +E ++ + E E
Sbjct: 602 REQEEMTQEQEEKMGEQE 619
Score = 40.8 bits (94), Expect = 0.005
Identities = 32/117 (27%), Positives = 63/117 (53%), Gaps = 9/117 (7%)
Query: 11 EEKEDETEESSSEEEE---EVEDKLPRRES-LRPKRKRTRDVINEDDPEPEPEDEETRKA 66
EEK E EE E+EE E E+K+ R+E +R + K+ R+ E E EE +
Sbjct: 612 EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE-----QEEKIREQEEMMQE 666
Query: 67 REKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEA 123
+E++ + ++ E+EE +E+ E+++ + ++ + ++ + KM++ E L+ A
Sbjct: 667 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 723
Score = 37.7 bits (86), Expect = 0.040
Identities = 27/101 (26%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
Query: 24 EEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEE 83
EE E+ ++L +++ K R + I E + + + ++E+ R+ EK R + K +EE
Sbjct: 347 EENELWNRLNQQQE--EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 404
Query: 84 I--DEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKE 122
+ EE++ R + + EK + + + W+ E+KI L+E
Sbjct: 405 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445
Score = 37.7 bits (86), Expect = 0.040
Identities = 33/144 (22%), Positives = 70/144 (48%), Gaps = 20/144 (13%)
Query: 7 QIKVEEKEDETEE-----SSSEEEEEV----------EDKLPRRES----LRPKRKRTRD 47
+I+ EEK E EE E+EE+ E+K+ ++E K +
Sbjct: 512 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEE 571
Query: 48 VINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVK 107
I E + + ++E+ R+ EK R + ++ E+EE+ +E+ E++ + ++ + ++
Sbjct: 572 KIREQEEKVWRQEEKIREQEEKIREQE-EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 630
Query: 108 CKPWKMEKKIEVLKEAKKFVSENE 131
+ KM ++ E ++E +K + E E
Sbjct: 631 EQEEKMRRQEEKIREQEKKIREQE 654
Score = 35.8 bits (81), Expect = 0.15
Identities = 20/86 (23%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EEK E E+ E+EE++ ++ + K + + E + + + ++E+ R+ EK
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699
Query: 71 RRRRLKRGAEEEEIDEEELERLKAEL 96
+ ++ +EE++ E + E L+A +
Sbjct: 700 WEQEVRLRQQEEKMQEHQ-EHLEAAI 724
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 52.4 bits (124), Expect = 2e-06
Identities = 36/127 (28%), Positives = 67/127 (52%), Gaps = 9/127 (7%)
Query: 1 MSPKKVQIKVEEKE--DETEESSSEEEEEVEDKLPR----RESLRPKRKRTRDVINEDDP 54
++ ++ +I+ EEK E E +EE E + ++ R R+ ++ + KR +
Sbjct: 288 IADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKE 347
Query: 55 EPEPEDEETRKAREKERR---RRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPW 111
E + EE ++ +E+E+R R + AEEEE + E ++ +L+EK+ + K K
Sbjct: 348 EEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGE 407
Query: 112 KMEKKIE 118
K+E+KIE
Sbjct: 408 KVEQKIE 414
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 15/97 (15%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRR----ESLRPKRKRTRDVINEDDPEPEPEDEETR 64
++EE E+ SEE E+++ K E L+ KR+ R V+ E++ + ++E R
Sbjct: 535 RLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE-QRRKQEEADR 593
Query: 65 KAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
K RE+E +RRLK EE+ER +AE EKRQ
Sbjct: 594 KLREEEEKRRLK----------EEIERRRAEAAEKRQ 620
Score = 40.4 bits (93), Expect = 0.006
Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 13/100 (13%)
Query: 3 PKKVQIKVEEKEDETEESSSEEEEE---VEDKLPRRESLRPKRKRTRDVINEDDPEPEPE 59
PK+ I + E EE ++E +EE + K + S PK++ R+ +++ E
Sbjct: 198 PKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKM 257
Query: 60 DEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEK 99
+EE ++ E ER R ++ EE ER+KAE D+K
Sbjct: 258 EEEDKERAEAERAR----------LEAEERERIKAEQDKK 287
Score = 39.7 bits (91), Expect = 0.011
Identities = 29/129 (22%), Positives = 54/129 (41%)
Query: 1 MSPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPED 60
MS K QI EE + E E +E +K+ + R + +R R E + +D
Sbjct: 226 MSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQD 285
Query: 61 EETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVL 120
++ R + E E + EE ER++ E + +K + + ++ + +
Sbjct: 286 KKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRI 345
Query: 121 KEAKKFVSE 129
KE +K +E
Sbjct: 346 KEEEKRAAE 354
Score = 38.9 bits (89), Expect = 0.018
Identities = 38/165 (23%), Positives = 71/165 (43%), Gaps = 28/165 (16%)
Query: 5 KVQIKVEEKEDETEESSSEEEEEVEDKLPRR-----------ESLRPKRKRTRDV----- 48
K K EE +DE + E +EEV+ + R+ E + K K T +
Sbjct: 455 KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPG 514
Query: 49 ----INEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEE------ELERLKAELDE 98
++ + E P+ E ++ E RRR E E++ ++ ELE LK + +E
Sbjct: 515 GRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE 574
Query: 99 KRQII--ATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKR 141
+R+++ + K + ++K+ +E ++ E E + KR
Sbjct: 575 RRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKR 619
Score = 38.5 bits (88), Expect = 0.023
Identities = 38/133 (28%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 15 DETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKER-RR 73
+E E +E+++++ D+ R E+ + R+ ++ E +EE R A E++R +
Sbjct: 275 EERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERE-RMREEEKRAAEERQRIKE 333
Query: 74 RLKRGAEE-EEIDEEEL----ERLKAELDEKRQIIATVKCKPWKMEK-KIEVLKEAKKFV 127
KR AEE + I EEE ER + + +EKR + + + EK K+E K K+ +
Sbjct: 334 EEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQ-L 392
Query: 128 SENEGALGKGKGK 140
E + A+ + K K
Sbjct: 393 EEKKHAMQETKIK 405
Score = 35.8 bits (81), Expect = 0.15
Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 14/130 (10%)
Query: 16 ETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRL 75
E E+ ++EE + ++++ R R + K E+ E+EE K E++R ++L
Sbjct: 333 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQL 392
Query: 76 ---KRGAEEEEIDEEELERL--------KAELDEKRQIIATVKC---KPWKMEKKIEVLK 121
K +E +I E++E+ K ++K Q K K K++ K E L+
Sbjct: 393 EEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQ 452
Query: 122 EAKKFVSENE 131
E K + E
Sbjct: 453 EDKPTFKKEE 462
Score = 34.7 bits (78), Expect = 0.34
Identities = 33/135 (24%), Positives = 68/135 (50%), Gaps = 8/135 (5%)
Query: 4 KKVQIKVEEKE--DETEESSSEEEEEVE-DKLPRRESLRPKRKRTRDV-INEDDPEPEPE 59
++ +IK EEK +E + + +EEEE+ + ++ R + L K+ ++ I + E + E
Sbjct: 355 ERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIE 414
Query: 60 DE--ETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKI 117
+ +KA+E + + + + EE+ + + +R K L E + + K K++K
Sbjct: 415 GKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREK--LQEDKPTFKKEEIKDEKIKKDK 472
Query: 118 EVLKEAKKFVSENEG 132
E +E K F+ +G
Sbjct: 473 EPKEEVKSFMDRKKG 487
Score = 32.0 bits (71), Expect = 2.2
Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 18/129 (13%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EE+ + + + E ++E + + P R+ D + E E + E ++ E E
Sbjct: 104 EERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIE 163
Query: 71 RRRRLK--------RGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKE 122
+ R AEE + +++E E + E ++ I E ++EV+ E
Sbjct: 164 ETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI----------GENQVEVMVE 213
Query: 123 AKKFVSENE 131
K S+ E
Sbjct: 214 EKTTESQEE 222
Score = 32.0 bits (71), Expect = 2.2
Identities = 21/91 (23%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Query: 14 EDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRR 73
+++T E+ + E+EE + R + T+ D + E E+++ K +E+E
Sbjct: 138 QNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE-ENKKEDKEKEEEEEE 196
Query: 74 RLKRGAEEEEIDEEELERLKAELDEKRQIIA 104
+ KRG+ E E +E E E+ +++
Sbjct: 197 KPKRGSIGENQVEVMVEEKTTESQEETVVMS 227
Score = 31.2 bits (69), Expect = 3.7
Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 30 DKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEEEL 89
D RR LR +++ + E +D+E ARE+ RR R +R +++E EE L
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQE--EESL 59
Query: 90 ERLKAELDEKRQ 101
++ +++ Q
Sbjct: 60 GQVTDQVEVNAQ 71
Score = 30.8 bits (68), Expect = 4.9
Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 25 EEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEI 84
E E + +RE +R + +R N+DD E E E R+AR++ R++ + + +
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEE-EAARERRRRARQERLRQKQEEESLGQVT 63
Query: 85 DEEELERLKAELDEKRQIIAT 105
D+ E+ + DE+ + T
Sbjct: 64 DQVEVNAQNSVPDEEAKTTTT 84
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 52.0 bits (123), Expect = 2e-06
Identities = 33/124 (26%), Positives = 69/124 (55%), Gaps = 7/124 (5%)
Query: 11 EEKEDETEESSSEEEE--EVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
+ + E E EEEE + E++L R E + +R+ E++ + E++ R+ E
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159
Query: 69 KERRRRLKRG-AEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFV 127
K RR+ L+R EEEE+ +EE + L+ E +++RQ + + ++ E++++ K +++
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEKRRQ----ERERQYREEEELQRQKRKQRYR 1215
Query: 128 SENE 131
E++
Sbjct: 1216 DEDQ 1219
Score = 49.7 bits (117), Expect = 1e-05
Identities = 29/89 (32%), Positives = 50/89 (56%)
Query: 13 KEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERR 72
+E E + EE ++ E++L R E + +R+ E++ + E++ R+ REK RR
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
Query: 73 RRLKRGAEEEEIDEEELERLKAELDEKRQ 101
+ L+R EEE ++E E+L E EKR+
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRR 1162
Score = 48.5 bits (114), Expect = 2e-05
Identities = 36/141 (25%), Positives = 67/141 (47%), Gaps = 27/141 (19%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLR---------------PKRKRTRDV 48
++ Q+ E+E + E+EE +E +L R E R P+ +R + +
Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633
Query: 49 INEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEID-----EEELERLKAELDEKRQII 103
+ ++ E E ++ R+ +++ R +RLKR EEE ++ E E ER + EL E+ Q
Sbjct: 634 LKSEEQE-ERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692
Query: 104 ATVKCK------PWKMEKKIE 118
A + K W++E + +
Sbjct: 693 ARERIKSRIPKWQWQLESEAD 713
Score = 47.4 bits (111), Expect = 5e-05
Identities = 25/89 (28%), Positives = 49/89 (55%)
Query: 12 EKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKER 71
E+E+ ++ EEE + +L R + R +++ R+ + + E E R+ E+ER
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Query: 72 RRRLKRGAEEEEIDEEELERLKAELDEKR 100
R++L + E+EE +++L R + E E+R
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQR 658
Score = 47.4 bits (111), Expect = 5e-05
Identities = 32/123 (26%), Positives = 68/123 (55%), Gaps = 16/123 (13%)
Query: 11 EEKEDETEESSSEEEEEV--EDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
+E++ EE +EEE++ E++ RR R ++ R + + + + E+ E R+ +E
Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKME--KKIEVLKEAKKF 126
+E++ R EEEE+ +EE + L+ E +++R+ + W+ + KK E+ +E ++
Sbjct: 986 REKKYR-----EEEELQQEEEQLLREEREKRRR-------QEWERQYRKKDELQQEEEQL 1033
Query: 127 VSE 129
+ E
Sbjct: 1034 LRE 1036
Score = 47.4 bits (111), Expect = 5e-05
Identities = 27/100 (27%), Positives = 59/100 (59%), Gaps = 7/100 (7%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEV--EDKLPRRESLRPKRKRTRDVINEDDPEPEPEDE 61
+K +++ E++ EE +EEE++ E++ RR ++ R + + +++ + E+
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Query: 62 ETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
E R+ +E+ER+ R EEEE+ +EE + L+ E +++R+
Sbjct: 1099 EKRRRQERERQCR-----EEEELQQEEEQLLREEREKRRR 1133
Score = 45.8 bits (107), Expect = 1e-04
Identities = 32/104 (30%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRES-LRPKRKRTRDVINEDDPEPEP---- 58
+K Q+K +++E+ E EEEE ++ RRE LR +++ R+ + E E
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531
Query: 59 -EDEETRKAREKERRRRLKRGAEEEEIDEEELE-RLKAELDEKR 100
E+ + ++ERR +L + EE+ +++E E RLK E +E+R
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/145 (28%), Positives = 67/145 (46%), Gaps = 21/145 (14%)
Query: 7 QIKVEE---KEDETEESSSEEEEEV-------EDKLPRRESLRPKRKRTRDVINEDDPEP 56
Q++ EE +ED+ S E+ + E++ RR +L K + E
Sbjct: 848 QLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907
Query: 57 EPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKK 116
E E+E R+ REK RR+ +R EEE ++E E+L E EKR+ + E++
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR----------RQERE 957
Query: 117 IEVLKEAKKFVSENEGALGKGKGKR 141
+ K+ KK + E LG+ KR
Sbjct: 958 RQYRKD-KKLQQKEEQLLGEEPEKR 981
Score = 45.1 bits (105), Expect = 3e-04
Identities = 32/128 (25%), Positives = 71/128 (55%), Gaps = 6/128 (4%)
Query: 4 KKVQIKVEEKED--ETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEP-EPED 60
++++ + EE+ D + EE + E+E + +R+ +R+R + E+ E E +
Sbjct: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504
Query: 61 EETRKAREKERRRRLKRGAEEEEIDE--EELERLKAELDEKR-QIIATVKCKPWKMEKKI 117
++ R+ +E+ R +RLKR EEE + + ++L+ E +E+R Q++ + K + E++
Sbjct: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
Query: 118 EVLKEAKK 125
+ LK ++
Sbjct: 565 QRLKREQE 572
Score = 45.1 bits (105), Expect = 3e-04
Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 22/133 (16%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVI--NEDDPEPEPEDEETRKARE 68
+E+ E EEEE ++ +L + LR +++ R+ + E++ E E E R RE
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 69 KERRR-------------RLKRGAEE---EEIDEEELERLKAELDEKRQIIATVKCKPWK 112
+E RR RLKR EE + + EE+ERL E +E+R+ +K + +
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL--EQEERRE--QRLKREEPE 626
Query: 113 MEKKIEVLKEAKK 125
E++ ++LK ++
Sbjct: 627 EERRQQLLKSEEQ 639
Score = 44.3 bits (103), Expect = 4e-04
Identities = 29/94 (30%), Positives = 53/94 (56%), Gaps = 9/94 (9%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
K+E +E E +EEE+ + +L R + LR K++ R + E E +E R+ +E
Sbjct: 280 KLERQELRRER---QEEEQQQQRLRREQQLRRKQEEER----REQQEERREQQERREQQE 332
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQI 102
+ R ++L+R E+EE E++L R + E ++Q+
Sbjct: 333 ERREQQLRR--EQEERREQQLRREQEEERREQQL 364
Score = 43.9 bits (102), Expect = 6e-04
Identities = 33/108 (30%), Positives = 57/108 (52%), Gaps = 7/108 (6%)
Query: 1 MSPKKVQIKVEEKE----DETEESSSEEEE--EVEDKLPRRESLRPKRKRTRDVINEDDP 54
+ K+ Q+ EE E E E+ EEEE + E++L R E + +R+ + D
Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
Query: 55 EPEPEDEETRKAREKER-RRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
+ E++ R+ REK R + R ++ EEEE+ +EE + L E + +R+
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Score = 43.5 bits (101), Expect = 7e-04
Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINED----DPEPEPEDEETR 64
K EEK E E E +E E++L + E +R+R + + + + + EE R
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 65 KAREKERRRRLKRGAEEEEIDEEELERLKAELDEKR 100
+ +++ERR + +R ++EE E++L R + E E++
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQ 350
Score = 43.5 bits (101), Expect = 7e-04
Identities = 31/127 (24%), Positives = 68/127 (53%), Gaps = 8/127 (6%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESL-RPKRKRTRDVINEDDPEPEPE-----DEETR 64
+ +++ E+ E+EE D L R E R +++R + + D E E +EE R
Sbjct: 437 KHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEER 496
Query: 65 KAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAK 124
+ +++ R ++L+R E+EE E+ L+R + E ++++ + + + + E++ ++LK +
Sbjct: 497 REQQERREQQLRR--EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Query: 125 KFVSENE 131
+ E E
Sbjct: 555 EKRLEQE 561
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/108 (25%), Positives = 57/108 (52%), Gaps = 6/108 (5%)
Query: 1 MSPKKVQIKVEEKE----DETEESSSEEEE--EVEDKLPRRESLRPKRKRTRDVINEDDP 54
+ ++ Q+ EE+E E E EEEE + E++L R E + +R+ E++
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
Query: 55 EPEPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQI 102
+ E++ R+ +EK R+ R ++ EEEE+ ++ ++ + D++ +
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDL 1223
Score = 42.0 bits (97), Expect = 0.002
Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 12/118 (10%)
Query: 11 EEKEDE---TEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAR 67
EEK E E+ E+EE D+L +RE R +++ R+ E+ E + EE +
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE--QEERLEQRLKREEVERLE 611
Query: 68 EKERR-RRLKRGAEEEE------IDEEELERLKAELDEKRQIIATVKCKPWKMEKKIE 118
++ERR +RLKR EEE EE+ ER + +L ++Q + K + E+++E
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/152 (22%), Positives = 77/152 (50%), Gaps = 29/152 (19%)
Query: 3 PKKVQIKVEEKEDETEESSSEEEEEV--EDKLPRRESLRPKRKRTRDVINEDDPEPEPED 60
P+K + + EK+ EE +EEE++ E++ RR ++ R +D + +++ + E+
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 61 EETRKAREKER------------------------RRRLKRG-AEEEEIDEEELERLKAE 95
E R+ +E+ER R+ L+R +EEE+ +EE + L+ E
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 96 LDEKRQIIATVKCKPWK--MEKKIEVLKEAKK 125
+++R+ +C+ + +++ ++L+E ++
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREERE 1129
Score = 41.2 bits (95), Expect = 0.004
Identities = 29/109 (26%), Positives = 59/109 (54%), Gaps = 12/109 (11%)
Query: 4 KKVQIKVEEKEDETEES--SSEEEEEVEDKLPRRESLRPKR--KRTRDVINEDDPEPEPE 59
++ Q++ E++E+ E+ +EEE E +L R + LR ++ +R + + E E +
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Query: 60 ---DEETRKAREKERRRRLKRGAEEEEID-----EEELERLKAELDEKR 100
+++ R+ ++ R ++L+R EEE + E +RLK E +E+R
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Score = 41.2 bits (95), Expect = 0.004
Identities = 33/150 (22%), Positives = 76/150 (50%), Gaps = 8/150 (5%)
Query: 10 VEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREK 69
++E+ + ++ EEEEE++ R E + +R+ E++ + E++ R+ REK
Sbjct: 895 LQEQLRKEQQLLQEEEEELQ----REEREKRRRQEQERQYREEEQLQQEEEQLLREEREK 950
Query: 70 ERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSE 129
RR+ +R +++ +++ E+L E EKR+ K K ++ E+ +E ++ + E
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK----KYREEEELQQEEEQLLRE 1006
Query: 130 NEGALGKGKGKRWFAFKMMMAKKWAKFLRD 159
+ + +R + K + ++ + LR+
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
Score = 41.2 bits (95), Expect = 0.004
Identities = 42/148 (28%), Positives = 74/148 (50%), Gaps = 16/148 (10%)
Query: 3 PKKVQIKVEE-KEDETEESSSEEE-----EEVEDKLPRRESLRPKRKRTRDVINEDDPEP 56
P++ Q++ EE KE + + S+EE EE E+K R+E+ R K + ++ E + +P
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR-KFREEEQLLQEREEQP 1352
Query: 57 EPEDEETRKAREKE-RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEK 115
E RK RE+E R + R EEE ER + L E++Q+ +C+ E+
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL----RCQ----ER 1404
Query: 116 KIEVLKEAKKFVSENEGALGKGKGKRWF 143
+ ++ ++ + E E L + + R F
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKF 1432
Score = 40.8 bits (94), Expect = 0.005
Identities = 29/133 (21%), Positives = 64/133 (48%), Gaps = 11/133 (8%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
K +E E + ++ ++ E++L E + +R+ E++ + E++ R+ RE
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVS 128
K RR+ +R +++ ++E E+L E EKR +++++ +E ++
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKR-----------RLQERERQYREEEELQQ 1058
Query: 129 ENEGALGKGKGKR 141
E E LG+ + R
Sbjct: 1059 EEEQLLGEERETR 1071
Score = 40.4 bits (93), Expect = 0.006
Identities = 31/111 (27%), Positives = 59/111 (53%), Gaps = 5/111 (4%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
+ EE++ ++ + EE E++L RRE L +RK + + E +D ++ E
Sbjct: 187 RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREE---KQQQRRERQDRVFQEEEE 243
Query: 69 KE-RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIE 118
KE R+R EEE++ EEE +R + EL E+ + + ++ + + E++ E
Sbjct: 244 KEWRKRETVLRKEEEKLQEEEPQR-QRELQEEEEQLRKLERQELRRERQEE 293
Score = 40.0 bits (92), Expect = 0.008
Identities = 23/94 (24%), Positives = 50/94 (53%), Gaps = 9/94 (9%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
++ K++E EE E +++ ++E R ++ R + E +++ R+ +E
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERREQQLRRE--------QEERREQQLRREQE 356
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQI 102
+ERR + R +EEE E++L R + +L ++Q+
Sbjct: 357 EERREQQLRREQEEERREQQLRR-EQQLRREQQL 389
Score = 40.0 bits (92), Expect = 0.008
Identities = 30/131 (22%), Positives = 68/131 (51%), Gaps = 12/131 (9%)
Query: 7 QIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINED------DPEPEPED 60
Q++ +E+E + + + E E +L R+E R R+ + V ++ + E +
Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457
Query: 61 EETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVL 120
E RK RE+E +L + EE+++ +E +R L+E++Q+ + + ++ E+++
Sbjct: 1458 ERHRKFREEE---QLLQEREEQQLHRQERDR--KFLEEEQQLRRQERDRKFR-EQELRSQ 1511
Query: 121 KEAKKFVSENE 131
+ +KF+ E +
Sbjct: 1512 EPERKFLEEEQ 1522
Score = 39.7 bits (91), Expect = 0.011
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 20/115 (17%)
Query: 7 QIKVEEKEDETEESSSE-----EEEEVEDKLPRR-----ESLRPKRKRTRDVINEDDPEP 56
Q +V ++E+E E E EEE+++++ P+R E RK R + + E
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 57 EPE------DEETRKAREKERRRRLKRGAEEEEIDEEELER----LKAELDEKRQ 101
E + +++ R+ +E+ERR + + E++E E++ ER L+ E +E+R+
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Score = 39.3 bits (90), Expect = 0.014
Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Query: 7 QIKVEEKEDETEESSSEEEEEV-EDKLPRRESLRPKRKRTRDVINEDDPE----PEPEDE 61
Q + E++ D T + +EE+ E +L R LR +R+R E PE E++
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEK 817
Query: 62 ETRKAREKERRRRLKRGAEEEEID-EEELERLKAELD 97
E R+ + +ER + L+ EEE++ E ++L+ E D
Sbjct: 818 EQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854
Score = 38.1 bits (87), Expect = 0.031
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 10/99 (10%)
Query: 13 KEDETEESSSEEE----EEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
K ETEE EE+ E +E + RE + +R+ +D + +++ E E ET +E
Sbjct: 197 KGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKE 256
Query: 69 KER------RRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
+E+ +R+ + EEE++ + E + L+ E E+ Q
Sbjct: 257 EEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ 295
Score = 38.1 bits (87), Expect = 0.031
Identities = 26/101 (25%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 7 QIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKA 66
Q++ E++E + EEE+ +E + R + L+ +++ RD + + E E + ++
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQE-RREQRLKREQEERRDQLLK--REEERRQQRLKRE 593
Query: 67 REKERRRRLKR----GAEEEEIDEEELERLKAELDEKRQII 103
+E+ +RLKR E+EE E+ L+R + E + ++Q++
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLL 634
Score = 38.1 bits (87), Expect = 0.031
Identities = 33/157 (21%), Positives = 73/157 (46%), Gaps = 24/157 (15%)
Query: 7 QIKVEEKEDETEESSSEEEEEVEDKLPRRESLRP-----------KRKRTRDVINEDDPE 55
Q++ EE++ + EEEE+ + + RRE + +R+R + + E+D
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGL 856
Query: 56 PEPEDEETRKAREKERRRRLKRGAEEEE-----------IDEEELERLKAELDEKRQIIA 104
E D+E R+++E+ R ++ + EEE +E+L + + L E+ + +
Sbjct: 857 QE--DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ 914
Query: 105 TVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKR 141
+ + + +++ +E ++ E E L + + KR
Sbjct: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951
Score = 37.4 bits (85), Expect = 0.052
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 9/97 (9%)
Query: 13 KEDETEESSSEEEEEVEDKLPRRES-LRPKRKRTRDVINEDDPEPEPEDEETRKAR---- 67
+E + EE E + + RRE L+ +++ RD + ++ E E ++E RK +
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE-ETERHEQERRKQQLKRD 479
Query: 68 --EKERRRRLKRGAEEEEIDEEELE-RLKAELDEKRQ 101
E+ R R LK EE +E E +L+ E +E+R+
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERRE 516
Score = 37.0 bits (84), Expect = 0.068
Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
Query: 11 EEKEDETEESSSE--EEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
EEK+ + E +EEE ++ R LR + ++ ++ + E + E+E+ RK
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 69 KE-RRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
+E RR R + +++ + E+ R K E + + Q
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317
Score = 36.6 bits (83), Expect = 0.089
Identities = 22/99 (22%), Positives = 54/99 (54%), Gaps = 7/99 (7%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEET 63
++ Q + E++E+ E+ E+EE ++ RRE +R++ + E E +++
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQL----RREQEEERREQQL 377
Query: 64 RKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQI 102
R+ ++ R ++L+R E+++ E+ R + +L ++Q+
Sbjct: 378 RREQQLRREQQLRR---EQQLRREQQLRREQQLRREQQL 413
Score = 36.2 bits (82), Expect = 0.12
Identities = 27/105 (25%), Positives = 57/105 (54%), Gaps = 7/105 (6%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRES-LRPKRKRTRDVINEDDPEPEPEDEE 62
++++ K EE+ E +E E++E E + RRE LR +++ R+ + E E +++
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 63 TRKA-----REKERRRRLKRGAEEEEIDEEELERLKAELDEKRQI 102
R+ RE++ RR + E++ E++L R + +L ++Q+
Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRR-EQQLRREQQL 407
Score = 36.2 bits (82), Expect = 0.12
Identities = 30/131 (22%), Positives = 67/131 (51%), Gaps = 4/131 (3%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRES-LRPKRKRTRDVINEDDPEPEPEDEETRKAREK 69
EE++ ++ES + EE + + R E LRP+++ + ++ + + E++E R +E+
Sbjct: 1784 EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK--YRWEEEQLQLEEQEQRLRQER 1841
Query: 70 ERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSE 129
+R+ R + +E E + L E ++KR+ K + + ++ + ++ + V E
Sbjct: 1842 DRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ-QKEEQRHRQVGE 1900
Query: 130 NEGALGKGKGK 140
+ GKG G+
Sbjct: 1901 IKSQEGKGHGR 1911
Score = 35.8 bits (81), Expect = 0.15
Identities = 31/143 (21%), Positives = 72/143 (50%), Gaps = 20/143 (13%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRES---LRPKRKRTRDVINEDDPEPE---PEDEE 62
KV K E E+ E+ ++ D+ +++ L +++R R+ + + PE+E+
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ 1298
Query: 63 TRKAREKERRRRLKRGAEEEEI--DEEELERLKAELD----EKRQIIATVKCKPWK---- 112
+ +KE +RR ++ EE+++ +E E +R + E D E+ Q++ + +P +
Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQER 1358
Query: 113 ----MEKKIEVLKEAKKFVSENE 131
E+++ ++ +KF+ E +
Sbjct: 1359 DRKFREEELRHQEQGRKFLEEEQ 1381
Score = 35.4 bits (80), Expect = 0.20
Identities = 23/101 (22%), Positives = 54/101 (53%), Gaps = 6/101 (5%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKR----KRTRDVINEDDPEPEPE 59
++ Q++ E++E ++ E+EEE ++ RRE +R +R + + E E +
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
Query: 60 DEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKR 100
++ R +++ RR ++ E+++ E+ +L+ E +E+R
Sbjct: 395 LRREQQLRREQQLRREQQLRREQQLRREQ--QLRREQEEER 433
Score = 35.4 bits (80), Expect = 0.20
Identities = 30/135 (22%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
K E+E + E + E++ RR+ L K + + E + E E RK E
Sbjct: 1692 KFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILE 1751
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVS 128
+E +L+ EE+++ +E +R E ++ RQ + + + ++K ++ ++
Sbjct: 1752 EE---QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
Query: 129 ENEGALGKGKGK-RW 142
E + + GK RW
Sbjct: 1809 EQQLRPQQRDGKYRW 1823
Score = 35.0 bits (79), Expect = 0.26
Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 16/143 (11%)
Query: 4 KKVQIKVEEKEDETEESSSEE--EEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDE 61
++++ K E+E +E+ E+ +E K+ E LRP+R + + E
Sbjct: 1719 QELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPER----------EEQQLRRQE 1768
Query: 62 ETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLK 121
RK RE+E +L++ EE+++ +E +R E ++ RQ + +P + + K +
Sbjct: 1769 RDRKFREEE---QLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR-WE 1824
Query: 122 EAKKFVSENEGALGKGKGKRWFA 144
E + + E E L + + +++ A
Sbjct: 1825 EEQLQLEEQEQRLRQERDRQYRA 1847
Score = 33.1 bits (74), Expect = 0.99
Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 33/154 (21%)
Query: 11 EEKEDETEESSSEEEE------EVEDKLPRRE---SLRPKRKR----TRDVINEDDPEPE 57
E+ E EE +E E E +L R+E LR R R ++ E + +
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL 1684
Query: 58 PEDEETRKAREKERR-----RRLKRGAEEEEIDEEELER-------LKAELDEK------ 99
E RK RE+E++ R K EE+++ +ELER L+ E +++
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE 1744
Query: 100 --RQIIATVKCKPWKMEKKIEVLKEAKKFVSENE 131
R+I+ + +P + E+++ + +KF E +
Sbjct: 1745 RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Score = 33.1 bits (74), Expect = 0.99
Identities = 27/124 (21%), Positives = 59/124 (47%), Gaps = 4/124 (3%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EE++ +E + EE E +L R+E R + + + ++ E+E+ R+ E+E
Sbjct: 1680 EEQQLRRQERDRKFREE-EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Query: 71 ---RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFV 127
R+ R ++ EEE++ E E+ + R+ + + + E+++ + +KF
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR 1798
Query: 128 SENE 131
E +
Sbjct: 1799 EEEQ 1802
Score = 32.7 bits (73), Expect = 1.3
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Query: 25 EEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEI 84
+EE + +ESL R++ ED EP D + + E +RRR KR +E E+
Sbjct: 96 DEEKRARCDGKESLLQDRRQ-----EEDQRRFEPRDRQLEE--EPGQRRRQKRQEQEREL 148
Query: 85 DEEELERLKAELDEKR 100
E E + K E E+R
Sbjct: 149 AEGEEQSEKQERLEQR 164
Score = 32.0 bits (71), Expect = 2.2
Identities = 26/134 (19%), Positives = 64/134 (47%), Gaps = 2/134 (1%)
Query: 7 QIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKA 66
Q + ++++ + E +E E +L R+E R R + V ++ EDE+ +
Sbjct: 1547 QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRR 1606
Query: 67 REKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPW--KMEKKIEVLKEAK 124
+E +++ R +R + E ++ ER + +L + + ++ +P + E++ ++ +
Sbjct: 1607 QEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD 1666
Query: 125 KFVSENEGALGKGK 138
+ E E L +G+
Sbjct: 1667 RKFREEEQLLQEGE 1680
Score = 31.6 bits (70), Expect = 2.9
Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 10/104 (9%)
Query: 8 IKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINED------DPEPEPEDE 61
++ +E++ + E +E+ L + LR +++R R + E+ + E + +
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLR-RQERERKFLKEEQQLRCQEREQQLRQD 1411
Query: 62 ETRKAREKER---RRRLKRGAEEEEIDEEELERLKAELDEKRQI 102
RK RE+E+ R+ R EEE ER + L+E++Q+
Sbjct: 1412 RDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL 1455
Score = 31.2 bits (69), Expect = 3.7
Identities = 26/106 (24%), Positives = 51/106 (48%), Gaps = 11/106 (10%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEET 63
++ Q++ E++ ++ E++ E +L R + LR +++ R+ + E E E+
Sbjct: 379 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE-RHEQK 437
Query: 64 RKAREKERRRRLKRGAE--------EEEIDEEELERLKAELDEKRQ 101
+ +E +RLKR E EEE + E ER K +L ++
Sbjct: 438 HEQERRE--QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Score = 31.2 bits (69), Expect = 3.7
Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
Query: 13 KEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERR 72
+E + +EE ++ E + E + +R+R R E E E + + + +RR
Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQR-------REREKELQFLEEEEQLQRR 843
Query: 73 RRLKRGAEEEEIDEEELERLKAELDEKRQ 101
R ++ EEE+ +E+ ER +++ + Q
Sbjct: 844 ERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
Score = 30.8 bits (68), Expect = 4.9
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Query: 13 KEDETEESSSEEEEE-VEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE- 70
+E+E + E E + +E++ R+ K + ++ E + + E RK E+E
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 71 --RRRRLKRGAEEEEIDEEELERLKAELDEKRQI 102
RR+ R E+E+ +E ER L+E++Q+
Sbjct: 1493 QLRRQERDRKFREQELRSQEPER--KFLEEEQQL 1524
Score = 30.4 bits (67), Expect = 6.4
Identities = 21/98 (21%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 5 KVQIKVEEKEDETEESSSEEEEEVEDKL-PRRESLRPKRKRTRDVINEDDPEPEPEDEET 63
K + + +++E + + ++E++ RR R +++R E + E ++
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRD 165
Query: 64 RKAREKE--RRRRLKRGAEEEEIDEEELERLKAELDEK 99
R+ R++E R+R+ + EE +EE+L+ K E+
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE 203
Score = 30.4 bits (67), Expect = 6.4
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 7/92 (7%)
Query: 12 EKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKER 71
E E + +S ++ RR+ KR+R E + + + E+ R+ +E+E+
Sbjct: 709 ESEADARQSKVYSRPRKQEGQRRRQEQEEKRRR-----RESELQWQEEERAHRQQQEEEQ 763
Query: 72 RRRLKRGAEEEEIDEEELERLKAE--LDEKRQ 101
RR + EE E +RL A L E+R+
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
Score = 30.4 bits (67), Expect = 6.4
Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINE----DDPEPEPEDEETRKA 66
E + E E EEE+++ + +R+ L+ +++ R + D E+E+ R+
Sbjct: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
Query: 67 REKERRRRLKRG----AEEEEIDEEELER 91
RE+++ R +R EE+++ +E ER
Sbjct: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQER 1595
Score = 30.0 bits (66), Expect = 8.3
Identities = 31/141 (21%), Positives = 68/141 (48%), Gaps = 24/141 (17%)
Query: 8 IKVEEKEDETEESSSEEEEEVEDKLPRRESLRP-----KRKRTRDVINEDDPEPEPEDEE 62
++ E++ E E+E+ + P R+ L +++R R + E E + +E
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE---EQQLRRQE 1544
Query: 63 TRKAREKERRRRLKRGAEEEEI--DEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVL 120
+ R ++R R+ + EEE++ + EE + + E D K ++ E+K+
Sbjct: 1545 RGQQRRQDRDRKFR---EEEQLRQEREEQQLSRQERDRKFRL----------EEQKVRRQ 1591
Query: 121 KEAKKFVSENEGALGKGKGKR 141
++ +KF+ E+E L + +G++
Sbjct: 1592 EQERKFM-EDEQQLRRQEGQQ 1611
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 15/97 (15%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRR----ESLRPKRKRTRDVINEDDPEPEPEDEETR 64
++EE E+ SEE E+++ K E L+ KR+ R V+ E++ + ++E R
Sbjct: 274 RLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE-QRRKQEEADR 332
Query: 65 KAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
K RE+E +RRLK EE+ER +AE EKRQ
Sbjct: 333 KLREEEEKRRLK----------EEIERRRAEAAEKRQ 359
Score = 38.1 bits (87), Expect = 0.031
Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 9/130 (6%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EE+ + + + E ++E + + P R+ D + E E + E ++ E E
Sbjct: 98 EERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIE 157
Query: 71 RRRRLK--------RGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKE 122
+ R AEE + +++E E + E KR I + K K++K E +E
Sbjct: 158 ETETVTKSYQKNDWRDAEENKKEDKEKEE-EEEEKPKRGSIGENQIKDEKIKKDKEPKEE 216
Query: 123 AKKFVSENEG 132
K F+ +G
Sbjct: 217 VKSFMDRKKG 226
Score = 38.1 bits (87), Expect = 0.031
Identities = 37/167 (22%), Positives = 72/167 (43%), Gaps = 28/167 (16%)
Query: 3 PKKVQIKVEEKEDETEESSSEEEEEVEDKLPRR-----------ESLRPKRKRTRDV--- 48
PK+ I + +DE + E +EEV+ + R+ E + K K T +
Sbjct: 192 PKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSR 251
Query: 49 ------INEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEE------ELERLKAEL 96
++ + E P+ E ++ E RRR E E++ ++ ELE LK +
Sbjct: 252 PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKR 311
Query: 97 DEKRQII--ATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKR 141
+E+R+++ + K + ++K+ +E ++ E E + KR
Sbjct: 312 EERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKR 358
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 15/97 (15%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRR----ESLRPKRKRTRDVINEDDPEPEPEDEETR 64
++EE E+ SEE E+++ K E L+ KR+ R V+ E++ + ++E R
Sbjct: 300 RLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE-QRRKQEEADR 358
Query: 65 KAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
K RE+E +RRLK EE+ER +AE EKRQ
Sbjct: 359 KLREEEEKRRLK----------EEIERRRAEAAEKRQ 385
Score = 38.9 bits (89), Expect = 0.018
Identities = 38/165 (23%), Positives = 71/165 (43%), Gaps = 28/165 (16%)
Query: 5 KVQIKVEEKEDETEESSSEEEEEVEDKLPRR-----------ESLRPKRKRTRDV----- 48
K K EE +DE + E +EEV+ + R+ E + K K T +
Sbjct: 220 KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPG 279
Query: 49 ----INEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEE------ELERLKAELDE 98
++ + E P+ E ++ E RRR E E++ ++ ELE LK + +E
Sbjct: 280 GRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE 339
Query: 99 KRQII--ATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKR 141
+R+++ + K + ++K+ +E ++ E E + KR
Sbjct: 340 RRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKR 384
Score = 38.5 bits (88), Expect = 0.023
Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 14/125 (11%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
E E E + S +E E+E+ +S + R + ++D E E E+EE
Sbjct: 139 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEE-------- 190
Query: 71 RRRRLKRGAEEEEIDEEELERLKA---ELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFV 127
+ KRG+ E EE+ +++A +L E + + K K++K E +E K F+
Sbjct: 191 ---KPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFM 247
Query: 128 SENEG 132
+G
Sbjct: 248 DRKKG 252
Score = 32.7 bits (73), Expect = 1.3
Identities = 22/93 (23%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
K + ++ E + +E+EE E++ P+R S+ + + + E ED+ T K +E
Sbjct: 168 KNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFK-KE 226
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
+ + ++K+ E +E + ++R K + K Q
Sbjct: 227 EIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQ 259
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 15/97 (15%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRR----ESLRPKRKRTRDVINEDDPEPEPEDEETR 64
++EE E+ SEE E+++ K E L+ KR+ R V+ E++ + ++E R
Sbjct: 306 RLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE-QRRKQEEADR 364
Query: 65 KAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
K RE+E +RRLK EE+ER +AE EKRQ
Sbjct: 365 KLREEEEKRRLK----------EEIERRRAEAAEKRQ 391
Score = 38.9 bits (89), Expect = 0.018
Identities = 38/165 (23%), Positives = 71/165 (43%), Gaps = 28/165 (16%)
Query: 5 KVQIKVEEKEDETEESSSEEEEEVEDKLPRR-----------ESLRPKRKRTRDV----- 48
K K EE +DE + E +EEV+ + R+ E + K K T +
Sbjct: 226 KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPG 285
Query: 49 ----INEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEE------ELERLKAELDE 98
++ + E P+ E ++ E RRR E E++ ++ ELE LK + +E
Sbjct: 286 GRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE 345
Query: 99 KRQII--ATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKR 141
+R+++ + K + ++K+ +E ++ E E + KR
Sbjct: 346 RRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKR 390
Score = 38.5 bits (88), Expect = 0.023
Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 14/125 (11%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
E E E + S +E E+E+ +S + R + ++D E E E+EE
Sbjct: 145 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEE-------- 196
Query: 71 RRRRLKRGAEEEEIDEEELERLKA---ELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFV 127
+ KRG+ E EE+ +++A +L E + + K K++K E +E K F+
Sbjct: 197 ---KPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFM 253
Query: 128 SENEG 132
+G
Sbjct: 254 DRKKG 258
Score = 32.7 bits (73), Expect = 1.3
Identities = 22/93 (23%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
K + ++ E + +E+EE E++ P+R S+ + + + E ED+ T K +E
Sbjct: 174 KNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFK-KE 232
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
+ + ++K+ E +E + ++R K + K Q
Sbjct: 233 EIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQ 265
Score = 31.2 bits (69), Expect = 3.7
Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 30 DKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEEEL 89
D RR LR +++ + E +D+E ARE+ RR R +R +++E EE L
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQE--EESL 59
Query: 90 ERLKAELDEKRQ 101
++ +++ Q
Sbjct: 60 GQVTDQVEVNAQ 71
Score = 30.8 bits (68), Expect = 4.9
Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 25 EEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEI 84
E E + +RE +R + +R N+DD E E E R+AR++ R++ + + +
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEE-EAARERRRRARQERLRQKQEEESLGQVT 63
Query: 85 DEEELERLKAELDEKRQIIAT 105
D+ E+ + DE+ + T
Sbjct: 64 DQVEVNAQNSVPDEEAKTTTT 84
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 15/97 (15%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRR----ESLRPKRKRTRDVINEDDPEPEPEDEETR 64
++EE E+ SEE E+++ K E L+ KR+ R V+ E++ + ++E R
Sbjct: 280 RLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE-QRRKQEEADR 338
Query: 65 KAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
K RE+E +RRLK EE+ER +AE EKRQ
Sbjct: 339 KLREEEEKRRLK----------EEIERRRAEAAEKRQ 365
Score = 38.1 bits (87), Expect = 0.031
Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 9/130 (6%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EE+ + + + E ++E + + P R+ D + E E + E ++ E E
Sbjct: 104 EERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIE 163
Query: 71 RRRRLK--------RGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKE 122
+ R AEE + +++E E + E KR I + K K++K E +E
Sbjct: 164 ETETVTKSYQKNDWRDAEENKKEDKEKEE-EEEEKPKRGSIGENQIKDEKIKKDKEPKEE 222
Query: 123 AKKFVSENEG 132
K F+ +G
Sbjct: 223 VKSFMDRKKG 232
Score = 38.1 bits (87), Expect = 0.031
Identities = 37/167 (22%), Positives = 72/167 (43%), Gaps = 28/167 (16%)
Query: 3 PKKVQIKVEEKEDETEESSSEEEEEVEDKLPRR-----------ESLRPKRKRTRDV--- 48
PK+ I + +DE + E +EEV+ + R+ E + K K T +
Sbjct: 198 PKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSR 257
Query: 49 ------INEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEE------ELERLKAEL 96
++ + E P+ E ++ E RRR E E++ ++ ELE LK +
Sbjct: 258 PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKR 317
Query: 97 DEKRQII--ATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKR 141
+E+R+++ + K + ++K+ +E ++ E E + KR
Sbjct: 318 EERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKR 364
Score = 31.2 bits (69), Expect = 3.7
Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 30 DKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEEEL 89
D RR LR +++ + E +D+E ARE+ RR R +R +++E EE L
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQE--EESL 59
Query: 90 ERLKAELDEKRQ 101
++ +++ Q
Sbjct: 60 GQVTDQVEVNAQ 71
Score = 30.8 bits (68), Expect = 4.9
Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 25 EEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEI 84
E E + +RE +R + +R N+DD E E E R+AR++ R++ + + +
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEE-EAARERRRRARQERLRQKQEEESLGQVT 63
Query: 85 DEEELERLKAELDEKRQIIAT 105
D+ E+ + DE+ + T
Sbjct: 64 DQVEVNAQNSVPDEEAKTTTT 84
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 51.6 bits (122), Expect = 3e-06
Identities = 43/178 (24%), Positives = 92/178 (51%), Gaps = 14/178 (7%)
Query: 9 KVEEKEDET---EESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRK 65
K++E+E+E EE E+EE+ ++K+ R+E K + + I E + E ++E+ R+
Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK---KMREQDEKIREQEEEMWRQEEKIRE 438
Query: 66 ARE--KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEA 123
E +++ +L+ E+ + +EE+++ + ++ + + I + K W+ EK +LK+
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK---LLKQE 495
Query: 124 KKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVP-WENKIKAIESQ 180
+K + E E + + + K W + M ++ K R E + V W+ + K E +
Sbjct: 496 EK-IWEQEEKMWRQEEKMWEQEEKMQEQE-EKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Score = 44.3 bits (103), Expect = 4e-04
Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 27/145 (18%)
Query: 11 EEKEDETEESSSEEE---EEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAR 67
EEK E EE E+E E E+K+ R+E K + I E + + ++E+ R+
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEE---KMHEQEEKIREQEDKMWRQEEKIREQE 359
Query: 68 EKERRRRLKRGAEEEEI---------DEEELERLK---AELDEKRQIIATVKCKPWKMEK 115
EK R + K +EE+I EEE+ R + E +EKRQ K W+ EK
Sbjct: 360 EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQE------KMWRQEK 413
Query: 116 KIEVLKEAKKFVSENEGALGKGKGK 140
K ++E + + E E + + + K
Sbjct: 414 K---MREQDEKIREQEEEMWRQEEK 435
Score = 43.1 bits (100), Expect = 0.001
Identities = 35/153 (22%), Positives = 78/153 (50%), Gaps = 13/153 (8%)
Query: 9 KVEEKEDET---EESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRK 65
K+ E+ED+ EE E+EE++ ++ + K + + I E + E ++E+ R+
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE 399
Query: 66 AREKER----RRRLKRGAEEEEID--EEELERLKAELDEKRQIIATVKCKPWKMEKKI-- 117
EK + R+ K ++E+I EEE+ R + ++ E +++ + K ++E+K+
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 118 --EVLKEAKKFVSENEGALGKGKGKRWFAFKMM 148
E ++E ++ + E + + + K W K++
Sbjct: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL 492
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/128 (24%), Positives = 66/128 (51%), Gaps = 13/128 (10%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
+VEEK E EE E+EE+++ + + + K R ++ +++ E E E
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE--------E 503
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVS 128
K R+ K +EE++ E+E E+++ + ++ R+ + + W+ E+K++ + + +
Sbjct: 504 KMWRQEEKMWEQEEKMQEQE-EKMQRQEEKMRE----QEVRLWQQEEKMQEQEVRLQELE 558
Query: 129 ENEGALGK 136
E G LG+
Sbjct: 559 ERLGKLGQ 566
Score = 40.8 bits (94), Expect = 0.005
Identities = 29/129 (22%), Positives = 66/129 (51%), Gaps = 8/129 (6%)
Query: 5 KVQIKVEEKE------DETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEP 58
K+Q +VEE E + EE +EE+++++ + K + + + + +
Sbjct: 277 KLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHE 336
Query: 59 EDEETRKAREKERRRRLKRGAEEEEIDEEE--LERLKAELDEKRQIIATVKCKPWKMEKK 116
++E+ R+ +K R+ K +EE+I E+E + R + ++ E+ + I + + W+ E+K
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Query: 117 IEVLKEAKK 125
I +E ++
Sbjct: 397 IREQEEKRQ 405
Score = 30.8 bits (68), Expect = 4.9
Identities = 33/146 (22%), Positives = 66/146 (45%), Gaps = 17/146 (11%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVED---KLPRRESLRPKRK------RTRDVINEDDP 54
K+ +++EK E SE + V+D KL R + L P+++ R +
Sbjct: 217 KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSA 276
Query: 55 EPEPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKME 114
+ + + EE +++ K +EE+I E+E + + EL + Q + K W+ E
Sbjct: 277 KLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQ-----EEKMWRQE 331
Query: 115 KKIEVLKEAKKFVSENEGALGKGKGK 140
+K + E ++ + E E + + + K
Sbjct: 332 EK---MHEQEEKIREQEDKMWRQEEK 354
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 51.6 bits (122), Expect = 3e-06
Identities = 43/178 (24%), Positives = 92/178 (51%), Gaps = 14/178 (7%)
Query: 9 KVEEKEDET---EESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRK 65
K++E+E+E EE E+EE+ ++K+ R+E K + + I E + E ++E+ R+
Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK---KMREQDEKIREQEEEMWRQEEKIRE 438
Query: 66 ARE--KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEA 123
E +++ +L+ E+ + +EE+++ + ++ + + I + K W+ EK +LK+
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK---LLKQE 495
Query: 124 KKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVP-WENKIKAIESQ 180
+K + E E + + + K W + M ++ K R E + V W+ + K E +
Sbjct: 496 EK-IWEQEEKMWRQEEKMWEQEEKMQEQE-EKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Score = 44.3 bits (103), Expect = 4e-04
Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 27/145 (18%)
Query: 11 EEKEDETEESSSEEE---EEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAR 67
EEK E EE E+E E E+K+ R+E K + I E + + ++E+ R+
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEE---KMHEQEEKIREQEDKMWRQEEKIREQE 359
Query: 68 EKERRRRLKRGAEEEEI---------DEEELERLK---AELDEKRQIIATVKCKPWKMEK 115
EK R + K +EE+I EEE+ R + E +EKRQ K W+ EK
Sbjct: 360 EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQE------KMWRQEK 413
Query: 116 KIEVLKEAKKFVSENEGALGKGKGK 140
K ++E + + E E + + + K
Sbjct: 414 K---MREQDEKIREQEEEMWRQEEK 435
Score = 43.1 bits (100), Expect = 0.001
Identities = 35/153 (22%), Positives = 78/153 (50%), Gaps = 13/153 (8%)
Query: 9 KVEEKEDET---EESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRK 65
K+ E+ED+ EE E+EE++ ++ + K + + I E + E ++E+ R+
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE 399
Query: 66 AREKER----RRRLKRGAEEEEID--EEELERLKAELDEKRQIIATVKCKPWKMEKKI-- 117
EK + R+ K ++E+I EEE+ R + ++ E +++ + K ++E+K+
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 118 --EVLKEAKKFVSENEGALGKGKGKRWFAFKMM 148
E ++E ++ + E + + + K W K++
Sbjct: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL 492
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/128 (24%), Positives = 66/128 (51%), Gaps = 13/128 (10%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
+VEEK E EE E+EE+++ + + + K R ++ +++ E E E
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE--------E 503
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVS 128
K R+ K +EE++ E+E E+++ + ++ R+ + + W+ E+K++ + + +
Sbjct: 504 KMWRQEEKMWEQEEKMQEQE-EKMQRQEEKMRE----QEVRLWQQEEKMQEQEVRLQELE 558
Query: 129 ENEGALGK 136
E G LG+
Sbjct: 559 ERLGKLGQ 566
Score = 40.8 bits (94), Expect = 0.005
Identities = 29/129 (22%), Positives = 66/129 (51%), Gaps = 8/129 (6%)
Query: 5 KVQIKVEEKE------DETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEP 58
K+Q +VEE E + EE +EE+++++ + K + + + + +
Sbjct: 277 KLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHE 336
Query: 59 EDEETRKAREKERRRRLKRGAEEEEIDEEE--LERLKAELDEKRQIIATVKCKPWKMEKK 116
++E+ R+ +K R+ K +EE+I E+E + R + ++ E+ + I + + W+ E+K
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Query: 117 IEVLKEAKK 125
I +E ++
Sbjct: 397 IREQEEKRQ 405
Score = 30.8 bits (68), Expect = 4.9
Identities = 33/146 (22%), Positives = 66/146 (45%), Gaps = 17/146 (11%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVED---KLPRRESLRPKRK------RTRDVINEDDP 54
K+ +++EK E SE + V+D KL R + L P+++ R +
Sbjct: 217 KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSA 276
Query: 55 EPEPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKME 114
+ + + EE +++ K +EE+I E+E + + EL + Q + K W+ E
Sbjct: 277 KLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQ-----EEKMWRQE 331
Query: 115 KKIEVLKEAKKFVSENEGALGKGKGK 140
+K + E ++ + E E + + + K
Sbjct: 332 EK---MHEQEEKIREQEDKMWRQEEK 354
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 51.2 bits (121), Expect = 3e-06
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 18/137 (13%)
Query: 11 EEKEDETEESSSEEEE--EVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
EEK E EE E+E+ E E+K E +R + KR E + + ++E+ R+ E
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR-----QEQEAKMWRQEEKIREQEE 444
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKI---EVLKEAKK 125
K R + K +EE+I E+E K +EKRQ + + W+ E+KI E + K+
Sbjct: 445 KIREQEKKMWRQEEKIHEQE----KIREEEKRQ----EQEEMWRQEEKIHEQEEIWRQKE 496
Query: 126 FVSENEGALGKGKGKRW 142
+ E E + K + K W
Sbjct: 497 KMHEQEEKIRKQEEKVW 513
Score = 49.7 bits (117), Expect = 1e-05
Identities = 35/136 (25%), Positives = 71/136 (52%), Gaps = 9/136 (6%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EEK E EE +EE++ ++ +R+ K + + I E + + + ++E+ R+ EK
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
Query: 71 RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKI----EVLKEAKKF 126
R + +EE++ E+E E++ E +EK Q + W+ E+KI + ++E ++
Sbjct: 636 REQEEMTQEQEEKMGEQE-EKM-CEQEEKMQ---EQEETMWRQEEKIREQEKKIREQEEK 690
Query: 127 VSENEGALGKGKGKRW 142
+ E E + + + K W
Sbjct: 691 IREQEEMMQEQEEKMW 706
Score = 48.9 bits (115), Expect = 2e-05
Identities = 36/142 (25%), Positives = 77/142 (54%), Gaps = 11/142 (7%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDE-- 61
+K++ + E++++E + E+ +E E K+ R+E K + + I E + + ++E
Sbjct: 404 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE---KIREQEEKIREQEKKMWRQEEKI 460
Query: 62 -ETRKAREKERRRRLKRGAEEEEI--DEEELERLKAELDEKRQIIATVKCKPWKMEKKIE 118
E K RE+E+R+ + +EE ++EE+ R K ++ E+ + I + K W+ E+KI
Sbjct: 461 HEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI- 519
Query: 119 VLKEAKKFVSENEGALGKGKGK 140
+E ++ + E E + + + K
Sbjct: 520 --REQEEKIREQEEKMWRQEEK 539
Score = 45.1 bits (105), Expect = 3e-04
Identities = 38/151 (25%), Positives = 76/151 (50%), Gaps = 21/151 (13%)
Query: 11 EEKEDETEESSSEEEEEV----------EDKLPRRESL----RPKRKRTRDVINEDDPEP 56
EEK E EE E+EE++ E+K+ R+E + K +R +++ E + +
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 57 EPEDEETRKAREKERRRRLKRGAEEEEIDE-----EELERLKAELDEKRQIIATVKCKPW 111
++E + EK RR+ +EE+I E E E+++ E +EKRQ ++ +
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR-EQEEKRQEEEKIREQEK 424
Query: 112 KMEKKIEVLKEAKKFVSENEGALGKGKGKRW 142
+ E++ ++ ++ +K + E E + + + K W
Sbjct: 425 RQEQEAKMWRQEEK-IREQEEKIREQEKKMW 454
Score = 44.7 bits (104), Expect = 3e-04
Identities = 40/131 (30%), Positives = 72/131 (54%), Gaps = 13/131 (9%)
Query: 9 KVEEKEDETEESSSEEEEEV---EDKLPRRES-LRPKRKRTRDVINEDDPEPEPEDEETR 64
K EEK EE E+EE++ E+K+ R+E +R + + R+ + E E+E+ +
Sbjct: 507 KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 65 KAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKI----EVL 120
+ +K R+ K +EE++ +E E+++ E +EKRQ + K WK E+KI E +
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQE-EKIR-EQEEKRQ---EQEEKMWKQEEKIREQEEKI 621
Query: 121 KEAKKFVSENE 131
+E ++ + E E
Sbjct: 622 QEQEEKIREQE 632
Score = 43.9 bits (102), Expect = 6e-04
Identities = 31/134 (23%), Positives = 68/134 (50%), Gaps = 8/134 (5%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
K EEK E EE E+EE++ + + E +R + + T++ + + E E+ K +E
Sbjct: 609 KQEEKIREQEEKIQEQEEKIRE---QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 665
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVS 128
+E + R E+ E+++ + ++ E+ +++ + K W+ E+K + E ++ +
Sbjct: 666 QE--ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK---MCEQEEKMQ 720
Query: 129 ENEGALGKGKGKRW 142
E E + + + K W
Sbjct: 721 EQEEKMRRQEEKMW 734
Score = 43.5 bits (101), Expect = 7e-04
Identities = 38/137 (27%), Positives = 69/137 (50%), Gaps = 16/137 (11%)
Query: 11 EEKEDETEESSSEEEE---EVEDKLPRRESL----RPKRKRTRDVINEDDP---EPEPED 60
EE E EE +EE E E+K+ R+E + K +R +++ E + E E +
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 400
Query: 61 EETRKAREKERRRRLKRGAEEEEIDEEE---LERLKAELDEKRQIIATVKCKPWKMEKKI 117
E K RE+E +R+ + E+E +E+ + R + ++ E+ + I + K W+ E+KI
Sbjct: 401 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 460
Query: 118 ---EVLKEAKKFVSENE 131
E ++E +K + E
Sbjct: 461 HEQEKIREEEKRQEQEE 477
Score = 43.5 bits (101), Expect = 7e-04
Identities = 38/146 (26%), Positives = 72/146 (49%), Gaps = 12/146 (8%)
Query: 7 QIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKA 66
+I+ EEK E EE +EE+ E + R+ + K + I + + + ++E+ R+
Sbjct: 465 KIREEEKRQEQEEMWRQEEKIHEQEEIWRQ--KEKMHEQEEKIRKQEEKVWRQEEKIREQ 522
Query: 67 REKERRRRLKRGAEEEEI-DEEELERLKAELDEKRQIIATVK-----CKPWKMEKKIEVL 120
EK R + K +EE+I ++EE+ R + ++ E+ +I K K W+ E+KI
Sbjct: 523 EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582
Query: 121 KE----AKKFVSENEGALGKGKGKRW 142
+E ++ + E E + + K W
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMW 608
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/143 (23%), Positives = 69/143 (48%), Gaps = 26/143 (18%)
Query: 9 KVEEKEDETEESSSEEEEEV---EDKLPRRESL---RPKRKRTRDVINEDDPEPEPEDEE 62
K+ E+E EE +E+EE+ E+K+ +E + + K + I + + + ++E+
Sbjct: 459 KIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK 518
Query: 63 TRKAREKERRRRLKRGAEEEEI-DEEELERLKAELDEKRQI------------------- 102
R+ EK R + K +EE+I ++EE+ R + ++ E+ +I
Sbjct: 519 IREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK 578
Query: 103 IATVKCKPWKMEKKIEVLKEAKK 125
I + K W+ E+KI +E ++
Sbjct: 579 IREQEEKVWRQEEKIREQEEKRQ 601
Score = 42.4 bits (98), Expect = 0.002
Identities = 28/134 (20%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
K+ E+E+ E E+E + +R+ K R + I E + + ++E+ R+ E
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVS 128
K + + K +EE+I E+E E+++ + ++ R+ ++ + +++ E + E ++ +
Sbjct: 599 KRQEQEEKMWKQEEKIREQE-EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 657
Query: 129 ENEGALGKGKGKRW 142
E E + + + W
Sbjct: 658 EQEEKMQEQEETMW 671
Score = 39.7 bits (91), Expect = 0.011
Identities = 26/112 (23%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKE 70
EE E EE E+EE++ ++ + + R + I E + + ++E+ R+ E
Sbjct: 639 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM 698
Query: 71 RRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKE 122
+ + K +EE++ E+E + + E +RQ + K W+ E ++ +E
Sbjct: 699 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ-----EEKMWEQEVRLRQQEE 745
Score = 38.9 bits (89), Expect = 0.018
Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 15/126 (11%)
Query: 5 KVQIKVEEKE------DETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEP 58
K+Q +VEE E + EE +EE++++ K + + I E + +
Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQE-------WEEKIQEQEEKIREQEEKIRE 332
Query: 59 EDEETRKAREK--ERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKK 116
++E+ R+ E E+ +++R E EE++ R + + EK + + + W+ E+K
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392
Query: 117 IEVLKE 122
I L+E
Sbjct: 393 IRELEE 398
Score = 36.2 bits (82), Expect = 0.12
Identities = 25/109 (22%), Positives = 58/109 (53%), Gaps = 9/109 (8%)
Query: 11 EEKEDETEESSSEEEEEVEDKLP----RRESLRPKRKRTRDVINEDDPEPEPEDEETRKA 66
EEK E EE E+EE+++++ + E +R + K+ R+ E E EE +
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE-----QEEKIREQEEMMQE 700
Query: 67 REKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEK 115
+E++ + ++ E+EE +E+ E+++ + ++ + ++ + KM++
Sbjct: 701 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 50.4 bits (119), Expect = 6e-06
Identities = 35/122 (28%), Positives = 68/122 (55%), Gaps = 25/122 (20%)
Query: 2 SPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDE 61
SP++++ + EKE E E+ +E+E+ +K +R++ R+ E + E E E E
Sbjct: 500 SPEEIREREREKEREREKELEKEQEQEREK---------EREKDRERQQEKEKELEKEQE 550
Query: 62 ETRKAREKERRRRLKRGAEEEEIDEEELERLK-----AELDEKRQIIATVKCKPWKMEKK 116
+ R+ EKER++ ++ E ++ E+EL+++K EL+++R+ K+E+K
Sbjct: 551 KQRE-MEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKERE----------KLEEK 599
Query: 117 IE 118
IE
Sbjct: 600 IE 601
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/127 (30%), Positives = 64/127 (50%), Gaps = 16/127 (12%)
Query: 9 KVEEKEDETEESSSEEE---EEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDE-ETR 64
+++EK E+ S EE E E + R + L ++++ R+ E D E + E E E
Sbjct: 487 RLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELE 546
Query: 65 KAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAK 124
K +EK+R +R E+ E+ELER K EK + + +K + EK+ E+ KE +
Sbjct: 547 KEQEKQREMEKERKQEK----EKELERQK----EKEKELQKMK----EQEKECELEKERE 594
Query: 125 KFVSENE 131
K + E
Sbjct: 595 KLEEKIE 601
Score = 40.4 bits (93), Expect = 0.006
Identities = 31/135 (22%), Positives = 67/135 (49%), Gaps = 21/135 (15%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPED--- 60
++ Q ++ + + EEE +E++ R+ + K KR + + + +P PE+
Sbjct: 449 RRQQSEISAAVERARKRREEEERRMEEQ--RKAACAEKLKRLDEKLGILEKQPSPEEIRE 506
Query: 61 ----------EETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKP 110
+E K +E+ER + ++ E ++ E+ELE+ E +++R++ K +
Sbjct: 507 REREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEK---EQEKQREM---EKERK 560
Query: 111 WKMEKKIEVLKEAKK 125
+ EK++E KE +K
Sbjct: 561 QEKEKELERQKEKEK 575
Score = 35.4 bits (80), Expect = 0.20
Identities = 24/99 (24%), Positives = 53/99 (53%), Gaps = 18/99 (18%)
Query: 1 MSPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPED 60
+ ++ Q + +E+E + E E+E+E+E + ++ + +RK ++
Sbjct: 519 LEKEQEQEREKEREKD-RERQQEKEKELEKEQEKQREMEKERK---------------QE 562
Query: 61 EETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEK 99
+E R+KE+ + L++ E+E+ E ELE+ + +L+EK
Sbjct: 563 KEKELERQKEKEKELQKMKEQEK--ECELEKEREKLEEK 599
Score = 30.4 bits (67), Expect = 6.4
Identities = 14/48 (29%), Positives = 27/48 (56%)
Query: 7 QIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDP 54
++K +EKE E E+ + EE++E + P E + K++ E++P
Sbjct: 579 KMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEP 626
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 49.7 bits (117), Expect = 1e-05
Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 12/153 (7%)
Query: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETR-KAREK 69
E D E SS+ ++ + +R+R R+ E + E E E E R + RE+
Sbjct: 364 ERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERER 423
Query: 70 ERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSE 129
ER + KR EE+E D E +L+ +L EK + + K W++ ++ + + K+ E
Sbjct: 424 EREKDKKRDREEDEEDAYERRKLERKLREK-EAAYQERLKNWEIRERKKTREYEKEAERE 482
Query: 130 NEGALGKGKGKRWFAFKMMMAKKWAKFLRDFEN 162
E K AK+ +FL D+++
Sbjct: 483 EERRREMAK----------EAKRLKEFLEDYDD 505
Score = 46.6 bits (109), Expect = 9e-05
Identities = 28/87 (32%), Positives = 44/87 (50%)
Query: 5 KVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETR 64
K I E E++ + S E + D + E + K+++ R I ++ E E E E R
Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERER 320
Query: 65 KAREKERRRRLKRGAEEEEIDEEELER 91
+ RE+ER R +R E+E+ E E ER
Sbjct: 321 ERREREREREREREREKEKERERERER 347
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/117 (24%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
Query: 9 KVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKARE 68
K+EE++ + E+ E E+E ++ RE R +R+R R+ E + E E E E R+ R+
Sbjct: 290 KLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERE-RD 348
Query: 69 KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKK 125
++R R +R + + + + +R ++ K + + K + + E++ E +E ++
Sbjct: 349 RDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERER 405
Score = 41.2 bits (95), Expect = 0.004
Identities = 31/110 (28%), Positives = 54/110 (49%), Gaps = 17/110 (15%)
Query: 4 KKVQIKVEEKEDETEE-----------SSSEEEEEVEDKLPRRESLRPKRKRTRDVINE- 51
+K++ K+ EKE +E + E E+E E + RR + + KR ++ + +
Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDY 503
Query: 52 DDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
DD +P + R ++RL+ +E E DE + +R K EL+E RQ
Sbjct: 504 DDDRDDP-----KYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQ 548
Score = 40.4 bits (93), Expect = 0.006
Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEET 63
KK++ + +KE E +E E E ++ RE +R+R R+ E + E E E E
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERD 348
Query: 64 R-----KAREKERRRRLKRGAEEEEIDEEELERLKA 94
R K R+++R R R + E + +R ++
Sbjct: 349 RDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRS 384
Score = 40.0 bits (92), Expect = 0.008
Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 9/98 (9%)
Query: 12 EKEDETEESSSEEEEEVEDKLPRRESLRPK-RKRTRDVINEDDPEPE-------PEDEET 63
E+E E E E + D+ R+ R + R R RD D + D E
Sbjct: 334 EREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRER 393
Query: 64 RKAREKERRRRLKRGAEEEEIDEEELER-LKAELDEKR 100
+ RE+ER R +R E E E E ER + E D+KR
Sbjct: 394 EREREREREREREREREREREREREREREREREKDKKR 431
Score = 39.3 bits (90), Expect = 0.014
Identities = 25/95 (26%), Positives = 49/95 (51%), Gaps = 17/95 (17%)
Query: 7 QIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKA 66
+++ EKE E +E + E+E +++ +R ++ E P+P+ E + +
Sbjct: 521 RLRDREKEMEADERDRKREKEELEEIRQR------------LLAEGHPDPDAELQRMEQE 568
Query: 67 REKERRRRLKRGAEEEEIDEEELERLKAELDEKRQ 101
E+ R+ ++K+ E EE +EE K E +EKR+
Sbjct: 569 AERRRQPQIKQEPESEEEEEE-----KQEKEEKRE 598
Score = 38.9 bits (89), Expect = 0.018
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 9/125 (7%)
Query: 12 EKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPE-----DEETRKA 66
E+E E E E E E E + + +R R RD E D + + E D E
Sbjct: 317 ERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSD 376
Query: 67 REKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKF 126
R K+R R ++ + E E E ER + E + +R+ + + + E++ E K+ K+
Sbjct: 377 RNKDRSRSREKSRDRERERERERER-ERERERERE---REREREREREREREREKDKKRD 432
Query: 127 VSENE 131
E+E
Sbjct: 433 REEDE 437
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 49.3 bits (116), Expect = 1e-05
Identities = 37/148 (25%), Positives = 80/148 (54%), Gaps = 19/148 (12%)
Query: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRT-----RDVINEDDPEPEP 58
K+ ++K E+K++E E+ E ++ EDK P ++ +PK++ +++ E+ EP+
Sbjct: 640 KETKVKPEDKKEEKEKPKKEVAKK-EDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKK 698
Query: 59 E------DEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWK 112
E +E +K +KE ++ +K+ EE+ ++E+++L + + ++ K KP
Sbjct: 699 EVKKETPPKEVKKEVKKEEKKEVKK---EEKEPKKEIKKLPKDAKKSSTPLSEAK-KPAA 754
Query: 113 MEKKIEVLKEAKKFVSENEGALGKGKGK 140
++ K+ +E+ V ++ A GK K K
Sbjct: 755 LKPKVPKKEES---VKKDSVAAGKPKEK 779
Score = 48.9 bits (115), Expect = 2e-05
Identities = 44/137 (32%), Positives = 70/137 (51%), Gaps = 12/137 (8%)
Query: 3 PKKVQIK--VEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPED 60
P K + K V EKE ++E S + EV +K + ++PK + + V E +PE +
Sbjct: 593 PIKTETKPSVTEKEVPSKEEPSPVKAEVAEK--QATDVKPKAAKEKTVKKETKVKPEDKK 650
Query: 61 EETRKAR----EKERRRRLKRGAEEEEIDEEELERLKAEL--DEKRQIIATVKCKPWKME 114
EE K + +KE + +K+ EE+ EE + +K E+ +EK++ VK + E
Sbjct: 651 EEKEKPKKEVAKKEDKTPIKK--EEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKE 708
Query: 115 KKIEVLKEAKKFVSENE 131
K EV KE KK V + E
Sbjct: 709 VKKEVKKEEKKEVKKEE 725
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/182 (23%), Positives = 88/182 (48%), Gaps = 10/182 (5%)
Query: 2 SPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDE 61
SP K ++ ++ D +++ E+ + E K+ + K K ++V ++D P ++E
Sbjct: 614 SPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEE 673
Query: 62 ETRKARE--KERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEV 119
+ +K E KE ++ +K+ EE++ ++E+++ + K+++ K + K EK E
Sbjct: 674 KPKK-EEVKKEVKKEIKK--EEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEK--EP 728
Query: 120 LKEAKKFVSE-NEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIE 178
KE KK + + + + K+ A K + KK +D + A + KIK I+
Sbjct: 729 KKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKD--SVAAGKPKEKGKIKVIK 786
Query: 179 SQ 180
+
Sbjct: 787 KE 788
Score = 35.0 bits (79), Expect = 0.26
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 17/131 (12%)
Query: 10 VEEKEDET---EESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKA 66
+E+ EDE EESS E + E+K E+ P+ V EDEE+ KA
Sbjct: 923 IEKFEDEGAGFEESS--ETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKA 980
Query: 67 RE----KERRRRLKRG---AEE---EEIDEEELERLKAELDE--KRQIIATVKCKPWKME 114
+E+R + G AEE E I++ E E+ + E DE K + + +P KME
Sbjct: 981 EADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKME 1040
Query: 115 KKIEVLKEAKK 125
+ V+ K
Sbjct: 1041 AEDYVMAVVDK 1051
Score = 33.1 bits (74), Expect = 0.99
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 10/129 (7%)
Query: 2 SPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDE 61
+P Q K++++ D S E + LP + + ++ T +V + E P+ E
Sbjct: 527 TPVVKQTKLKQRAD-----SRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVE 581
Query: 62 ETRKA---REKERRRRLKRGAEEEEI-DEEELERLKAELDEKRQIIATVK-CKPWKMEKK 116
K ++K + K E+E+ +EE +KAE+ EK+ K K ++K+
Sbjct: 582 SKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKE 641
Query: 117 IEVLKEAKK 125
+V E KK
Sbjct: 642 TKVKPEDKK 650
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,700,518
Number of Sequences: 37866
Number of extensions: 1348486
Number of successful extensions: 24232
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 405
Number of HSP's successfully gapped in prelim test: 757
Number of HSP's that attempted gapping in prelim test: 10565
Number of HSP's gapped (non-prelim): 7426
length of query: 760
length of database: 18,247,518
effective HSP length: 110
effective length of query: 650
effective length of database: 14,082,258
effective search space: 9153467700
effective search space used: 9153467700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.