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Search of human proteins with 21071032
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
(622 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 1238 0.0
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 292 5e-79
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 290 4e-78
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 288 1e-77
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 288 1e-77
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 285 1e-76
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 285 1e-76
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 277 2e-74
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 271 1e-72
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 267 2e-71
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 267 2e-71
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 256 6e-68
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 256 6e-68
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 256 6e-68
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 249 4e-66
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 247 3e-65
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 224 2e-58
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 208 1e-53
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 206 7e-53
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 201 2e-51
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 199 6e-51
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 199 6e-51
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 196 4e-50
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 192 6e-49
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi... 192 6e-49
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 192 8e-49
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 187 2e-47
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 182 1e-45
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 181 1e-45
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 181 1e-45
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 1238 bits (3204), Expect = 0.0
Identities = 622/622 (100%), Positives = 622/622 (100%)
Query: 1 MEESEPERKRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKGAAE 60
MEESEPERKRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKGAAE
Sbjct: 1 MEESEPERKRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKGAAE 60
Query: 61 EEQQDSGSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEKQLKEEEKILESV 120
EEQQDSGSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEKQLKEEEKILESV
Sbjct: 61 EEQQDSGSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEKQLKEEEKILESV 120
Query: 121 AEGRALMSVKEMAKGITYDDPIKTSWTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPI 180
AEGRALMSVKEMAKGITYDDPIKTSWTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPI
Sbjct: 121 AEGRALMSVKEMAKGITYDDPIKTSWTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPI 180
Query: 181 KSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVI 240
KSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVI
Sbjct: 181 KSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVI 240
Query: 241 MFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGG 300
MFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGG
Sbjct: 241 MFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGG 300
Query: 301 MSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRT 360
MSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRT
Sbjct: 301 MSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRT 360
Query: 361 IFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAK 420
IFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAK
Sbjct: 361 IFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAK 420
Query: 421 MVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFRE 480
MVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFRE
Sbjct: 421 MVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFRE 480
Query: 481 GKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKAC 540
GKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKAC
Sbjct: 481 GKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKAC 540
Query: 541 DESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDIGGERGCAFCGGLGHRITDCPKLEA 600
DESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDIGGERGCAFCGGLGHRITDCPKLEA
Sbjct: 541 DESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDIGGERGCAFCGGLGHRITDCPKLEA 600
Query: 601 MQTKQVSNIGRKDYLAHSSMDF 622
MQTKQVSNIGRKDYLAHSSMDF
Sbjct: 601 MQTKQVSNIGRKDYLAHSSMDF 622
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 292 bits (748), Expect = 5e-79
Identities = 170/439 (38%), Positives = 253/439 (57%), Gaps = 30/439 (6%)
Query: 173 GDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKT 232
G+ PP I+SF +++ I+ ++ PTP+Q IP I RD++ A TGSGKT
Sbjct: 172 GNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKT 231
Query: 233 LVFTLPVI--MFCLEQEKRLPFSKREGPYG--------LIICPSRELARQTHGILEYYCR 282
F LP++ ++ + L K G YG L++ P+RELA ++ Y
Sbjct: 232 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELA------VQIYEE 285
Query: 283 LLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLA 342
+ +R + GG + +Q+ + G H++VATPGRL+D++++ + LD C+YL
Sbjct: 286 ARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLV 345
Query: 343 LDEADRMIDMGFEGDIRTIFSYF----KGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398
LDEADRM+DMGFE IR I KG R T++FSAT PK+IQ A+ L + + + V
Sbjct: 346 LDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 405
Query: 399 GRAGAASLDVIQEVEYVKEEAKMVYLLECLQKTPPP--VLIFAEKKADVDAIHEYLLLKG 456
GR G+ S ++ Q+V +V+E K +LL+ L T L+F E K D++ ++L +G
Sbjct: 406 GRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEG 465
Query: 457 VEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENY 516
+IHG + Q +R +A+ FR GK +LVAT VA++GLD ++HVIN+D+P +IE Y
Sbjct: 466 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEY 525
Query: 517 VHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVL----HCGDES 572
VHRIGRTGR GN G+AT+F N+ + ++ DL LL+EAKQ+VP L+ + H S
Sbjct: 526 VHRIGRTGRVGNLGLATSFFNER-NINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSS 584
Query: 573 MLDIGGERGCAFCGGLGHR 591
G + F GG G R
Sbjct: 585 R---GRSKSSRFSGGFGAR 600
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 290 bits (741), Expect = 4e-78
Identities = 203/604 (33%), Positives = 311/604 (51%), Gaps = 60/604 (9%)
Query: 2 EESEPERKRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKGAAEE 61
+E E +R R + G E + E+ L ++ L + +RRR +
Sbjct: 210 QERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLND 269
Query: 62 EQ---QDSGSEPRGDEDDIPLGPQSNVSLLDQH--QHLKEKAEARKESAKEKQLKEEEKI 116
+ + SE + + + V LL + + K + R++S L E+ +
Sbjct: 270 RKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRT 329
Query: 117 LESVAEGRA-LMSVKEMAKGITYDDPIKTSWTPPRYVLSMSEERHERV-RKKYHILVEGD 174
LE + A L +++ +DD W+ + L +R R+ R+ Y I +G
Sbjct: 330 LEEKEQEEARLRKLRKKEAKQRWDD---RHWSQKK--LDEMTDRDWRIFREDYSITTKGG 384
Query: 175 GIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLV 234
IP PI+S+K+ P IL + K G PTPIQ Q IP L RD+IG+A TGSGKT
Sbjct: 385 KIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAA 444
Query: 235 FTLPVIMF--CLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDS---- 288
F +P++++ L + R+ S +GPY +I+ P+RELA+Q ++E++
Sbjct: 445 FLIPLLVWITTLPKIDRIEESD-QGPYAIILAPTRELAQQ-----------IEEETIKFG 492
Query: 289 SPL-LRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEAD 347
PL +R IGG+S ++Q +R G +++ATPGRL+D+L+ + + L C Y+ LDEAD
Sbjct: 493 KPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEAD 552
Query: 348 RMIDMGFEGDIRTIFSYF--------------------------KGQRQTLLFSATMPKK 381
RMIDMGFE D++ I + RQT++F+ATMP
Sbjct: 553 RMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPA 612
Query: 382 IQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAKMVYLLECL-QKTPPPVLIFAE 440
++ A+S L +P + +G AG V Q+V + E K LL L Q PP++IF
Sbjct: 613 VERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVN 672
Query: 441 KKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPA 500
+K D + + L G A +HGGK QE+R A+ + G KD+LVATDVA +G+D
Sbjct: 673 QKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQD 732
Query: 501 IQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAK-QKV 559
+ V+NYDM + IE+Y+HRIGRTGR+G +G+A TF+ K D +V +LK +LE+
Sbjct: 733 VSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKE-DSAVFYELKQAILESPVSSC 791
Query: 560 PPVL 563
PP L
Sbjct: 792 PPEL 795
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 288 bits (736), Expect = 1e-77
Identities = 169/439 (38%), Positives = 252/439 (57%), Gaps = 30/439 (6%)
Query: 173 GDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKT 232
G PP I++F ++ I+ ++ PTP+Q IP I RD++ A TGSGKT
Sbjct: 170 GSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKT 229
Query: 233 LVFTLPVI--MFCLEQEKRLPFSKREGPYG--------LIICPSRELARQTHGILEYYCR 282
F LP++ ++ + L K G YG L++ P+RELA ++ Y
Sbjct: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELA------VQIYEE 283
Query: 283 LLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLA 342
+ +R + GG + +Q+ + G H++VATPGRL+D++++ + LD C+YL
Sbjct: 284 ARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLV 343
Query: 343 LDEADRMIDMGFEGDIRTIFSYF----KGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398
LDEADRM+DMGFE IR I KG R T++FSAT PK+IQ A+ L + + + V
Sbjct: 344 LDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 403
Query: 399 GRAGAASLDVIQEVEYVKEEAKMVYLLECLQKTPPP--VLIFAEKKADVDAIHEYLLLKG 456
GR G+ S ++ Q+V +V++ K +LL+ L T L+F E K D++ ++L +G
Sbjct: 404 GRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEG 463
Query: 457 VEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENY 516
+IHG + Q +R +A+ FR GK +LVAT VA++GLD ++HVIN+D+P +IE Y
Sbjct: 464 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEY 523
Query: 517 VHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDI 576
VHRIGRTGR GN G+AT+F N+ + ++ DL LL+EAKQ+VP L+ +
Sbjct: 524 VHRIGRTGRVGNLGLATSFFNEK-NMNITKDLLDLLVEAKQEVPSWLENMAYEHHYK--- 579
Query: 577 GGERGCA----FCGGLGHR 591
GG RG + F GG G R
Sbjct: 580 GGSRGRSKSNRFSGGFGAR 598
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 288 bits (736), Expect = 1e-77
Identities = 169/439 (38%), Positives = 252/439 (57%), Gaps = 30/439 (6%)
Query: 173 GDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKT 232
G PP I++F ++ I+ ++ PTP+Q IP I RD++ A TGSGKT
Sbjct: 170 GSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKT 229
Query: 233 LVFTLPVI--MFCLEQEKRLPFSKREGPYG--------LIICPSRELARQTHGILEYYCR 282
F LP++ ++ + L K G YG L++ P+RELA ++ Y
Sbjct: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELA------VQIYEE 283
Query: 283 LLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLA 342
+ +R + GG + +Q+ + G H++VATPGRL+D++++ + LD C+YL
Sbjct: 284 ARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLV 343
Query: 343 LDEADRMIDMGFEGDIRTIFSYF----KGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398
LDEADRM+DMGFE IR I KG R T++FSAT PK+IQ A+ L + + + V
Sbjct: 344 LDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 403
Query: 399 GRAGAASLDVIQEVEYVKEEAKMVYLLECLQKTPPP--VLIFAEKKADVDAIHEYLLLKG 456
GR G+ S ++ Q+V +V++ K +LL+ L T L+F E K D++ ++L +G
Sbjct: 404 GRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEG 463
Query: 457 VEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENY 516
+IHG + Q +R +A+ FR GK +LVAT VA++GLD ++HVIN+D+P +IE Y
Sbjct: 464 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEY 523
Query: 517 VHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDI 576
VHRIGRTGR GN G+AT+F N+ + ++ DL LL+EAKQ+VP L+ +
Sbjct: 524 VHRIGRTGRVGNLGLATSFFNEK-NMNITKDLLDLLVEAKQEVPSWLENMAYEHHYK--- 579
Query: 577 GGERGCA----FCGGLGHR 591
GG RG + F GG G R
Sbjct: 580 GGSRGRSKSNRFSGGFGAR 598
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 285 bits (728), Expect = 1e-76
Identities = 214/622 (34%), Positives = 308/622 (49%), Gaps = 64/622 (10%)
Query: 9 KRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQR--RQLLLQKLLQRRRKG------AAE 60
KRA DE A E ED + D +PY+P RQ K + AE
Sbjct: 65 KRANFDEENAY-FEDEEEDSSNVD-LPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAE 122
Query: 61 EEQQDSGSEPRGDEDDIPLGPQSNVSLL--------DQHQHLKEKAEARKESAKEKQLKE 112
E Q + R +E D + NV + DQ + + AE ++ E
Sbjct: 123 VEDQAARDMKRLEEKD---KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQE---E 176
Query: 113 EEKILESVAEGRALMSVKEMA--------KGITYDDPIKTSWTPPRYVLSMSEERHERVR 164
EE LE ++G + K++ I Y K + + +++ ++ +R
Sbjct: 177 EEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLR 236
Query: 165 KKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGI 224
K ++ V G P P SF F ++ ++K PTPIQ QG+P LSGRDMIGI
Sbjct: 237 HKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGI 296
Query: 225 AFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLL 284
A TGSGKT F P+++ ++Q++ P +GP +I+CP+REL +Q H + + +
Sbjct: 297 AKTGSGKTAAFIWPMLIHIMDQKELEP---GDGPIAVIVCPTRELCQQIHAECKRFGKAY 353
Query: 285 QEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALD 344
LR GG S+ EQ + ++ G ++V TPGRL+D ++KK +L YL D
Sbjct: 354 N------LRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFD 407
Query: 345 EADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAA 404
EADRM DMGFE +R+I S+ + RQTLLFSAT KKI+ A+ L+ P+ + G G A
Sbjct: 408 EADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEA 467
Query: 405 SLDVIQEVEYVKE-EAKMVYLLECLQK--TPPPVLIFAEKKADVDAIHEYLLLKGVEAVA 461
+ DV Q VE + +K +L L + + VL+F KKA+ + + L +G
Sbjct: 468 NEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGL 527
Query: 462 IHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIG 521
+HG DQ ER K I F++ VLVATDVA++GLD P+I+ VINYD+ +I+ + HRIG
Sbjct: 528 LHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIG 587
Query: 522 RTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHC------------G 569
RTGR+G G+A T + D + DL L A Q V L L G
Sbjct: 588 RTGRAGEKGVAYTLLTPK-DSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646
Query: 570 DESMLDIGGERGCAFCGGLGHR 591
L+IGG GGLG+R
Sbjct: 647 KGKKLNIGG-------GGLGYR 661
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 285 bits (728), Expect = 1e-76
Identities = 214/622 (34%), Positives = 308/622 (49%), Gaps = 64/622 (10%)
Query: 9 KRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQR--RQLLLQKLLQRRRKG------AAE 60
KRA DE A E ED + D +PY+P RQ K + AE
Sbjct: 65 KRANFDEENAY-FEDEEEDSSNVD-LPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAE 122
Query: 61 EEQQDSGSEPRGDEDDIPLGPQSNVSLL--------DQHQHLKEKAEARKESAKEKQLKE 112
E Q + R +E D + NV + DQ + + AE ++ E
Sbjct: 123 VEDQAARDMKRLEEKD---KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQE---E 176
Query: 113 EEKILESVAEGRALMSVKEMA--------KGITYDDPIKTSWTPPRYVLSMSEERHERVR 164
EE LE ++G + K++ I Y K + + +++ ++ +R
Sbjct: 177 EEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLR 236
Query: 165 KKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGI 224
K ++ V G P P SF F ++ ++K PTPIQ QG+P LSGRDMIGI
Sbjct: 237 HKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGI 296
Query: 225 AFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLL 284
A TGSGKT F P+++ ++Q++ P +GP +I+CP+REL +Q H + + +
Sbjct: 297 AKTGSGKTAAFIWPMLIHIMDQKELEP---GDGPIAVIVCPTRELCQQIHAECKRFGKAY 353
Query: 285 QEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALD 344
LR GG S+ EQ + ++ G ++V TPGRL+D ++KK +L YL D
Sbjct: 354 N------LRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFD 407
Query: 345 EADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAA 404
EADRM DMGFE +R+I S+ + RQTLLFSAT KKI+ A+ L+ P+ + G G A
Sbjct: 408 EADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEA 467
Query: 405 SLDVIQEVEYVKE-EAKMVYLLECLQK--TPPPVLIFAEKKADVDAIHEYLLLKGVEAVA 461
+ DV Q VE + +K +L L + + VL+F KKA+ + + L +G
Sbjct: 468 NEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGL 527
Query: 462 IHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIG 521
+HG DQ ER K I F++ VLVATDVA++GLD P+I+ VINYD+ +I+ + HRIG
Sbjct: 528 LHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIG 587
Query: 522 RTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHC------------G 569
RTGR+G G+A T + D + DL L A Q V L L G
Sbjct: 588 RTGRAGEKGVAYTLLTPK-DSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646
Query: 570 DESMLDIGGERGCAFCGGLGHR 591
L+IGG GGLG+R
Sbjct: 647 KGKKLNIGG-------GGLGYR 661
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 277 bits (708), Expect = 2e-74
Identities = 177/484 (36%), Positives = 256/484 (52%), Gaps = 27/484 (5%)
Query: 89 DQHQHLKEKAEARKESAKEKQLKEEEKILESVAEGRALMSVKEMAKGITYDDPIKTSWTP 148
D ++ E+ E ++A ++ K+LE V G+ I Y+ K +
Sbjct: 290 DAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGK-----------IEYEPFRKNFYVE 338
Query: 149 PRYVLSMSEERHERVRKKYH-ILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPI 207
+ MS+E R + I V+G G P PIKS+ + IL LKK G PTPI
Sbjct: 339 VPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPI 398
Query: 208 QIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSR 267
Q Q IP I+SGRD+IGIA TGSGKT+ F LP+ ++Q + EGP +I+ P+R
Sbjct: 399 QTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRS---LEEGEGPIAVIMTPTR 455
Query: 268 ELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDL 327
ELA Q + + + L LR GG + EQ+ ++ G ++V TPGR++D+
Sbjct: 456 ELALQITKECKKFSKTLG------LRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDM 509
Query: 328 LQK---KMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQN 384
L ++ +L Y+ LDEADRM DMGFE + I + RQT++FSAT P+ ++
Sbjct: 510 LAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEA 569
Query: 385 FAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAKMVYLLECL--QKTPPPVLIFAEKK 442
A+ L KP+ + VG DV Q+V ++EE K + LLE L + V+IF +K+
Sbjct: 570 LARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQ 629
Query: 443 ADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQ 502
D + + L+ +++HGG DQ +R I F+ G +LVAT VA++GLD +
Sbjct: 630 EHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLI 689
Query: 503 HVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPV 562
V+NY P E+YVHR GRTGR+GN G A TFI + +KAL L VPP
Sbjct: 690 LVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSG-TAVPPD 748
Query: 563 LQVL 566
L+ L
Sbjct: 749 LEKL 752
Score = 32.7 bits (73), Expect = 1.0
Identities = 20/87 (22%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Query: 49 KLLQRRRKGAAEEEQQDSGSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEK 108
K + R + + + +S E + D+DD + + DQ++ L+E+ RKE ++
Sbjct: 112 KKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNK-LEEEMRKRKERVEKW 170
Query: 109 QLKEEEKILESVAEGRALMSVKEMAKG 135
+ ++ +K +E++ G ++EM +G
Sbjct: 171 REEQRKKAMENI--GELKKEIEEMKQG 195
Score = 31.2 bits (69), Expect = 3.0
Identities = 24/107 (22%), Positives = 42/107 (39%)
Query: 9 KRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKGAAEEEQQDSGS 68
+R+R+ + RS + D+ LR+ R + +RRR + + + S S
Sbjct: 38 RRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRS 97
Query: 69 EPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEKQLKEEEK 115
R P + + + E+ KE K+K KE+EK
Sbjct: 98 RGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEK 144
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 271 bits (694), Expect = 1e-72
Identities = 159/409 (38%), Positives = 228/409 (55%), Gaps = 17/409 (4%)
Query: 161 ERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRD 220
E R+ I V G P P+ +F E FPA ++ + ++ PT IQ QG P LSG D
Sbjct: 74 ETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLD 133
Query: 221 MIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKR-EGPYGLIICPSRELARQTHGILEY 279
M+G+A TGSGKTL + LP I+ Q PF +R +GP L++ P+RELA+Q +
Sbjct: 134 MVGVAQTGSGKTLSYLLPAIVHINHQ----PFLERGDGPICLVLAPTRELAQQVQQVAAE 189
Query: 280 YCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICR 339
YCR + L+ GG Q+ + GV + +ATPGRL+D L+ +L
Sbjct: 190 YCRACR------LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTT 243
Query: 340 YLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVG 399
YL LDEADRM+DMGFE IR I + RQTL++SAT PK+++ A+ L + IN+G
Sbjct: 244 YLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIG 303
Query: 400 RAGAAS----LDVIQEVEYVKEEAKMVYLLE-CLQKTPPPVLIFAEKKADVDAIHEYLLL 454
++ L ++ V+++ K++ L+E + + ++F E K D + +
Sbjct: 304 ALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRR 363
Query: 455 KGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIE 514
G A+ IHG K Q+ER + F+ GK +L+ATDVAS+GLD ++ VINYD P E
Sbjct: 364 DGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSE 423
Query: 515 NYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVL 563
+Y+HRIGRT RS TG A TF + V DL ++L EA Q + P L
Sbjct: 424 DYIHRIGRTARSTKTGTAYTFFTPNNIKQV-SDLISVLREANQAINPKL 471
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 267 bits (683), Expect = 2e-71
Identities = 165/413 (39%), Positives = 230/413 (55%), Gaps = 18/413 (4%)
Query: 161 ERVRKKYHILVEG-DGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGR 219
+ +R+K I V G D P P+ +F FP ++ L + PTPIQ QG P LSGR
Sbjct: 150 DELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGR 209
Query: 220 DMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKR-EGPYGLIICPSRELARQTHGILE 278
DM+GIA TGSGKTL + LP I+ Q P+ +R +GP L++ P+RELA+Q + +
Sbjct: 210 DMVGIAQTGSGKTLAYLLPAIVHINHQ----PYLERGDGPICLVLAPTRELAQQVQQVAD 265
Query: 279 YYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDIC 338
Y + + L+ GG Q+ + GV + +ATPGRL+D L+ +L C
Sbjct: 266 DYGKCSR------LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRC 319
Query: 339 RYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398
YL LDEADRM+DMGFE IR I + RQTL++SAT PK+++ A+ L INV
Sbjct: 320 TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINV 379
Query: 399 GRAG-AASLDVIQEVEYVKE---EAKMVYLL-ECLQKTPPPVLIFAEKKADVDAIHEYLL 453
G +A+ +++Q V+ E + K++ L+ E + + +IF E K D + +
Sbjct: 380 GNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMR 439
Query: 454 LKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEI 513
G A+ IHG K Q ER + FR GK +L+ATDVAS+GLD ++ VINYD P
Sbjct: 440 RDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSS 499
Query: 514 ENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVL 566
E+YVHRIGRT RS N G A TF + +L +L EA Q + P L L
Sbjct: 500 EDYVHRIGRTARSTNKGTAYTFFTPG-NLKQARELIKVLEEANQAINPKLMQL 551
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 267 bits (683), Expect = 2e-71
Identities = 165/413 (39%), Positives = 230/413 (55%), Gaps = 18/413 (4%)
Query: 161 ERVRKKYHILVEG-DGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGR 219
+ +R+K I V G D P P+ +F FP ++ L + PTPIQ QG P LSGR
Sbjct: 150 DELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGR 209
Query: 220 DMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKR-EGPYGLIICPSRELARQTHGILE 278
DM+GIA TGSGKTL + LP I+ Q P+ +R +GP L++ P+RELA+Q + +
Sbjct: 210 DMVGIAQTGSGKTLAYLLPAIVHINHQ----PYLERGDGPICLVLAPTRELAQQVQQVAD 265
Query: 279 YYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDIC 338
Y + + L+ GG Q+ + GV + +ATPGRL+D L+ +L C
Sbjct: 266 DYGKCSR------LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRC 319
Query: 339 RYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398
YL LDEADRM+DMGFE IR I + RQTL++SAT PK+++ A+ L INV
Sbjct: 320 TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINV 379
Query: 399 GRAG-AASLDVIQEVEYVKE---EAKMVYLL-ECLQKTPPPVLIFAEKKADVDAIHEYLL 453
G +A+ +++Q V+ E + K++ L+ E + + +IF E K D + +
Sbjct: 380 GNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMR 439
Query: 454 LKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEI 513
G A+ IHG K Q ER + FR GK +L+ATDVAS+GLD ++ VINYD P
Sbjct: 440 RDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSS 499
Query: 514 ENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVL 566
E+YVHRIGRT RS N G A TF + +L +L EA Q + P L L
Sbjct: 500 EDYVHRIGRTARSTNKGTAYTFFTPG-NLKQARELIKVLEEANQAINPKLMQL 551
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 256 bits (653), Expect = 6e-68
Identities = 154/401 (38%), Positives = 221/401 (55%), Gaps = 13/401 (3%)
Query: 171 VEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSG 230
V G PP I +F+E + + K G TP+Q IP IL+GRD++ A TGSG
Sbjct: 278 VSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSG 337
Query: 231 KTLVFTLPVIMFCLEQEKRLP-FSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSS 289
KT F LP++ + F + + P +I+ P+REL Q Y +
Sbjct: 338 KTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQI------YLEARKFSFG 391
Query: 290 PLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRM 349
+R + GG + + I G +++ ATPGRLMD++ K+ + L +YL LDEADRM
Sbjct: 392 TCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRM 451
Query: 350 IDMGFEGDIRTIFSY----FKGQRQTLLFSATMPKKIQNFAKSALVKP-VTINVGRAGAA 404
+DMGF +++ + S K QRQTL+FSAT P++IQ A L + + VG+ G A
Sbjct: 452 LDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGA 511
Query: 405 SLDVIQEVEYVKEEAKMVYLLECLQKTPPP-VLIFAEKKADVDAIHEYLLLKGVEAVAIH 463
DV Q V V + +K L+E L+ ++F E K D I +L + + +IH
Sbjct: 512 CRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIH 571
Query: 464 GGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRT 523
G ++Q ER +A+ FR GK VLVAT VA++GLD +QHVIN+D+P I+ YVHRIGRT
Sbjct: 572 GDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRT 631
Query: 524 GRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQ 564
GR GNTG A +F + D + L +L +A+Q VP L+
Sbjct: 632 GRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLE 672
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 256 bits (653), Expect = 6e-68
Identities = 154/401 (38%), Positives = 221/401 (55%), Gaps = 13/401 (3%)
Query: 171 VEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSG 230
V G PP I +F+E + + K G TP+Q IP IL+GRD++ A TGSG
Sbjct: 278 VSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSG 337
Query: 231 KTLVFTLPVIMFCLEQEKRLP-FSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSS 289
KT F LP++ + F + + P +I+ P+REL Q Y +
Sbjct: 338 KTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQI------YLEARKFSFG 391
Query: 290 PLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRM 349
+R + GG + + I G +++ ATPGRLMD++ K+ + L +YL LDEADRM
Sbjct: 392 TCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRM 451
Query: 350 IDMGFEGDIRTIFSY----FKGQRQTLLFSATMPKKIQNFAKSALVKP-VTINVGRAGAA 404
+DMGF +++ + S K QRQTL+FSAT P++IQ A L + + VG+ G A
Sbjct: 452 LDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGA 511
Query: 405 SLDVIQEVEYVKEEAKMVYLLECLQKTPPP-VLIFAEKKADVDAIHEYLLLKGVEAVAIH 463
DV Q V V + +K L+E L+ ++F E K D I +L + + +IH
Sbjct: 512 CRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIH 571
Query: 464 GGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRT 523
G ++Q ER +A+ FR GK VLVAT VA++GLD +QHVIN+D+P I+ YVHRIGRT
Sbjct: 572 GDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRT 631
Query: 524 GRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQ 564
GR GNTG A +F + D + L +L +A+Q VP L+
Sbjct: 632 GRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLE 672
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 256 bits (653), Expect = 6e-68
Identities = 154/401 (38%), Positives = 221/401 (55%), Gaps = 13/401 (3%)
Query: 171 VEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSG 230
V G PP I +F+E + + K G TP+Q IP IL+GRD++ A TGSG
Sbjct: 244 VSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSG 303
Query: 231 KTLVFTLPVIMFCLEQEKRLP-FSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSS 289
KT F LP++ + F + + P +I+ P+REL Q Y +
Sbjct: 304 KTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQI------YLEARKFSFG 357
Query: 290 PLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRM 349
+R + GG + + I G +++ ATPGRLMD++ K+ + L +YL LDEADRM
Sbjct: 358 TCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRM 417
Query: 350 IDMGFEGDIRTIFSY----FKGQRQTLLFSATMPKKIQNFAKSALVKP-VTINVGRAGAA 404
+DMGF +++ + S K QRQTL+FSAT P++IQ A L + + VG+ G A
Sbjct: 418 LDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGA 477
Query: 405 SLDVIQEVEYVKEEAKMVYLLECLQKTPPP-VLIFAEKKADVDAIHEYLLLKGVEAVAIH 463
DV Q V V + +K L+E L+ ++F E K D I +L + + +IH
Sbjct: 478 CRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIH 537
Query: 464 GGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRT 523
G ++Q ER +A+ FR GK VLVAT VA++GLD +QHVIN+D+P I+ YVHRIGRT
Sbjct: 538 GDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRT 597
Query: 524 GRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQ 564
GR GNTG A +F + D + L +L +A+Q VP L+
Sbjct: 598 GRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLE 638
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 249 bits (637), Expect = 4e-66
Identities = 157/472 (33%), Positives = 245/472 (51%), Gaps = 37/472 (7%)
Query: 111 KEEEKILESVAEGRALMSVKEMAKGITYDDPIKTSWTPPR------------YVLSMSEE 158
K +E + + + L+ VKE + +P K P ++L++ E+
Sbjct: 121 KTDEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQED 180
Query: 159 RHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSG 218
+ E ++++ ILV+G + PI F+ P + LKK G PTPIQ+Q IP L G
Sbjct: 181 QIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLG 240
Query: 219 RDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILE 278
RD++ A TGSGKT F LPVIM L + K P LI+ P+RELA Q +E
Sbjct: 241 RDILASADTGSGKTAAFLLPVIMRALFESKT--------PSALILTPTRELAIQ----IE 288
Query: 279 YYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDIC 338
+ L P ++ L +GG+ + Q+ ++ V +++ATPGRL+D++++ V L
Sbjct: 289 RQAKELMS-GLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGV 347
Query: 339 RYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398
+ + +DEAD M+ MGF+ + I QT+L SAT+P I+ A L PV I
Sbjct: 348 KIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIIT 407
Query: 399 GRAGAASLDVIQEVEYVKEEAKMVYLLECLQKT---PPPVLIFAEKKADVDAIHEYL-LL 454
G +V Q + +V++ AK L E L PPVL+F + K D + E + +
Sbjct: 408 GEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKI 467
Query: 455 KGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIE 514
G+++++IH K Q ER ++ EG +V+V+T V +GLD +++ V+N+DMP ++
Sbjct: 468 TGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMD 527
Query: 515 NYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVL 566
YVH+IGR GR G G A TFIN + K L + ++V P +L
Sbjct: 528 EYVHQIGRVGRLGQNGTAITFINN--------NSKRLFWDIAKRVKPTGSIL 571
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 247 bits (630), Expect = 3e-65
Identities = 148/392 (37%), Positives = 218/392 (55%), Gaps = 14/392 (3%)
Query: 176 IPPPIKSFKE-MKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLV 234
IP P +F + + ++ +KK G PTPIQ Q P +L G D+IG+A TG+GKTL
Sbjct: 236 IPNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLC 295
Query: 235 FTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRC 294
+ +P + + Q +R P L++ P+RELA Q G Y S LR
Sbjct: 296 YLMPGFIHLVLQPSLK--GQRNRPGMLVLTPTRELALQVEGECCKY-------SYKGLRS 346
Query: 295 ALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGF 354
GG + EQ+E ++ GV +++ATPGRL DL V+L YL LDEAD+M+DMGF
Sbjct: 347 VCVYGGGNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGF 406
Query: 355 EGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVI-QEVE 413
E I I + RQT++ SAT P + A+S L +P+ + VG ++ + Q +
Sbjct: 407 EPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNII 466
Query: 414 YVKEEAKMVYLLECLQK--TPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEER 471
EE K ++ LQ + V++F +KA D + L+L + ++HG ++Q +R
Sbjct: 467 VTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDR 526
Query: 472 TKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGI 531
KA+E F+ GK +L+ATD+AS+GLD + HV N+D P IE YVHRIGRTGR+G TG+
Sbjct: 527 EKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGV 586
Query: 532 ATTFINKACDESVLMDLKALLLEAKQKVPPVL 563
+ T + + D V +L +L A Q +P L
Sbjct: 587 SITTLTRN-DWRVASELINILERANQSIPEEL 617
>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
Length = 631
Score = 224 bits (570), Expect = 2e-58
Identities = 139/396 (35%), Positives = 211/396 (53%), Gaps = 16/396 (4%)
Query: 176 IPPPIKSFKE--MKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTL 233
IP P FK+ ++P +L+ + + GI PTPIQ Q P IL G D+I +A TG+GKTL
Sbjct: 216 IPKPTCRFKDAFQQYPD-LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTL 274
Query: 234 VFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLR 293
+ +P + Q + +R GP L++ P+RELA Y S L+
Sbjct: 275 SYLMPGFIHLDSQP--ISREQRNGPGMLVLTPTRELALHVEAECSKY-------SYKGLK 325
Query: 294 CALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMG 353
GG + Q+E I GV +++ATPGRL DL V+L YL +DEAD+M+DM
Sbjct: 326 SICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDME 385
Query: 354 FEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVI-QEV 412
FE IR I + RQT++ SAT P ++ A S L P+ + VG +++ + Q +
Sbjct: 386 FEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNI 445
Query: 413 EYVKEEAKMVYLLECLQKTPP--PVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEE 470
E+ K E ++ P V++F +K D + ++G+ A ++HG +Q +
Sbjct: 446 IVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSD 505
Query: 471 RTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTG 530
+ +A+E F+ G +L+ TD+ S+GLD + HV NYD P I+ YVHR+G GR+G TG
Sbjct: 506 QERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTG 565
Query: 531 IATTFINKACDESVLMDLKALLLEAKQKVPPVLQVL 566
+ T I + D + +L +L A Q VP L V+
Sbjct: 566 TSVTLITQR-DSKMAGELIKILDRANQSVPEDLVVM 600
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 208 bits (529), Expect = 1e-53
Identities = 166/580 (28%), Positives = 279/580 (48%), Gaps = 45/580 (7%)
Query: 14 DEVPAGGSRSEAEDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKGA-------AEEEQQDS 66
DEVP E++ D+E+ P V R+ QK L + R E+E
Sbjct: 46 DEVPV---EPESDSGDEEEEGPIVLGRR------QKALGKNRSADFNPDFVFTEKEGTYD 96
Query: 67 GSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEKQLKEEEKILESVAEGRAL 126
GS D ++ +L ++ + +++K + + AK +L++E++ E +E +
Sbjct: 97 GSWALADVMSQLKKKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEG-SEPKEQ 155
Query: 127 MSVKEMAKGITYDDPIKTSWTPP-RYVLSMSEERHERVRKKYHIL-VEGDGIPPPIK--- 181
++E + + D+ +T ++ +L+ ++ + RKK E G
Sbjct: 156 EDLQENDEEGSEDEASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYD 215
Query: 182 ---SFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLP 238
SF++M +L+ + G PTPIQ IP L G+D+ A TG+GKT F LP
Sbjct: 216 ENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALP 275
Query: 239 VIMFCLEQEKRLPFSKREGPYG--LIICPSRELARQTHGILEYYCRLLQEDSSPLLRCAL 296
V+ +RL + R+ P L++ P+REL Q H + + + L
Sbjct: 276 VL-------ERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCN------ITTCL 322
Query: 297 CIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQK-KMVSLDICRYLALDEADRMIDMGFE 355
+GG+ VK Q +R +++ATPGRL+D L L L LDEADRM+D FE
Sbjct: 323 AVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFE 382
Query: 356 GDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYV 415
++ I RQT+LFSATM ++++ A +L PV I V + + QE +
Sbjct: 383 EQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRI 442
Query: 416 K---EEAKMVYLLECLQKT-PPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEER 471
+ E + + L +T V++F + K +H L L G++ +HG Q +R
Sbjct: 443 RPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQR 502
Query: 472 TKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGI 531
+A+ F++ + D+LVATDVA++GLD ++ VIN+ MP I++YVHR+GRT R+G G
Sbjct: 503 LEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGR 562
Query: 532 ATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHCGDE 571
+ + + + + + +KA K ++ P +L D+
Sbjct: 563 SVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDK 602
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 206 bits (523), Expect = 7e-53
Identities = 127/360 (35%), Positives = 196/360 (54%), Gaps = 16/360 (4%)
Query: 181 KSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVI 240
K+FK++ + + G PT IQI+ IP L GRD+IG+A TGSGKT F LP++
Sbjct: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
Query: 241 MFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGG 300
LE +RL + L++ P+RELA Q I E + L SS ++ A+ +GG
Sbjct: 84 NALLETPQRL--------FALVLTPTRELAFQ---ISEQFEAL---GSSIGVQSAVIVGG 129
Query: 301 MSVKEQMETIRHGVHMMVATPGRLMDLLQK-KMVSLDICRYLALDEADRMIDMGFEGDIR 359
+ Q + H+++ATPGRL+D L+ K +L +YL +DEADR+++M FE ++
Sbjct: 130 IDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVD 189
Query: 360 TIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEA 419
I R+T LFSATM KK+Q ++AL PV V + Q ++ +
Sbjct: 190 KILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKF 249
Query: 420 KMVYLLECLQKTPP-PVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAF 478
K YL+ L + +IF + L G A+ +HG Q +R ++ F
Sbjct: 250 KDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKF 309
Query: 479 REGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINK 538
+ + +L+ATDVAS+GLD P + V+N+D+P ++Y+HR+GRT R+G +G A TF+ +
Sbjct: 310 KAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ 369
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 201 bits (511), Expect = 2e-51
Identities = 140/488 (28%), Positives = 249/488 (51%), Gaps = 28/488 (5%)
Query: 92 QHLKEKAEARKESAKEKQLKEEEKILESVA---EGRALMSVKEMAKGITYDDPIKTSWTP 148
Q+ ++K E+ E +E+ K+ + + +A EG + + + I + S
Sbjct: 69 QNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKKVQRESKLT 128
Query: 149 PRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEM----KFPAAILRGLKKKGIHHP 204
+ ++ +E+ +R K+ I V+G +P PI +F+++ K + +L+ + G P
Sbjct: 129 SGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMP 188
Query: 205 TPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIIC 264
TPIQ+Q IP +L GR+++ A TGSGKTL F++P++M +L +G LII
Sbjct: 189 TPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM-------QLKQPANKGFRALIIS 241
Query: 265 PSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRL 324
P+RELA Q H L + + A+ K + ++V TP RL
Sbjct: 242 PTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKK-----FDILVTTPNRL 296
Query: 325 MDLLQKKMVSLDIC--RYLALDEADRMID---MGFEGDIRTIFSYFKGQR-QTLLFSATM 378
+ LL++ +D+ +L +DE+D++ + GF + +IF + + +FSAT
Sbjct: 297 IYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATF 356
Query: 379 PKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYV-KEEAKMVYLLECLQKT-PPPVL 436
++ + K L +++++G +A V QE+ +V E K++ + E ++K PPVL
Sbjct: 357 AYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVL 416
Query: 437 IFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGL 496
+F + + L+ +G+ IH + Q++R + +FR GK VL+ T + ++G+
Sbjct: 417 VFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGI 476
Query: 497 DFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAK 556
DF + VINYD P Y+HRIGRTGR+GN G A TF + D+ +L + ++ +A
Sbjct: 477 DFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTED-DKPLLRSVANVIQQAG 535
Query: 557 QKVPPVLQ 564
VP ++
Sbjct: 536 CPVPEYIK 543
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 199 bits (506), Expect = 6e-51
Identities = 126/374 (33%), Positives = 196/374 (52%), Gaps = 18/374 (4%)
Query: 183 FKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMF 242
F+ M + +G+ KKG PTPIQ + IP IL G+D++ +A TGSGKT F LP+
Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMF-- 155
Query: 243 CLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMS 302
E+ S + G LI+ P+RELA QT L++ L + L+ AL +GG
Sbjct: 156 ----ERLKTHSAQTGARALILSPTRELALQT---LKFTKELGKFTG---LKTALILGGDR 205
Query: 303 VKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTIF 362
+++Q + +++ATPGRL+ + + + L Y+ DEADR+ +MGF ++ I
Sbjct: 206 MEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEII 265
Query: 363 SYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAKMV 422
+ G QT+LFSAT+PK + FA++ L +PV I + + + V+E+ K
Sbjct: 266 ARLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAA 325
Query: 423 YLLECLQKTPPP---VLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFR 479
LL L P ++F K + + E L + V I+ D R + F
Sbjct: 326 VLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFT 385
Query: 480 EGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKA 539
GK L+ TD+A++GLD P + +VINY P + + ++HR+GR R+G +G A + + A
Sbjct: 386 LGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLV--A 443
Query: 540 CDE-SVLMDLKALL 552
DE L+DL L
Sbjct: 444 PDEIPYLLDLHLFL 457
Score = 29.6 bits (65), Expect = 8.7
Identities = 17/65 (26%), Positives = 31/65 (47%)
Query: 43 RQLLLQKLLQRRRKGAAEEEQQDSGSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARK 102
R L Q + +R+K + G + R ++ + P+GP + L + Q KE+ E
Sbjct: 583 RDLCSQVMRAKRQKDRKAIARFQQGQQGRQEQQEGPVGPAPSRPALQEKQPEKEEEEEAG 642
Query: 103 ESAKE 107
ES ++
Sbjct: 643 ESVED 647
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 199 bits (506), Expect = 6e-51
Identities = 126/374 (33%), Positives = 196/374 (52%), Gaps = 18/374 (4%)
Query: 183 FKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMF 242
F+ M + +G+ KKG PTPIQ + IP IL G+D++ +A TGSGKT F LP+
Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMF-- 155
Query: 243 CLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMS 302
E+ S + G LI+ P+RELA QT L++ L + L+ AL +GG
Sbjct: 156 ----ERLKTHSAQTGARALILSPTRELALQT---LKFTKELGKFTG---LKTALILGGDR 205
Query: 303 VKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTIF 362
+++Q + +++ATPGRL+ + + + L Y+ DEADR+ +MGF ++ I
Sbjct: 206 MEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEII 265
Query: 363 SYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAKMV 422
+ G QT+LFSAT+PK + FA++ L +PV I + + + V+E+ K
Sbjct: 266 ARLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAA 325
Query: 423 YLLECLQKTPPP---VLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFR 479
LL L P ++F K + + E L + V I+ D R + F
Sbjct: 326 VLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFT 385
Query: 480 EGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKA 539
GK L+ TD+A++GLD P + +VINY P + + ++HR+GR R+G +G A + + A
Sbjct: 386 LGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLV--A 443
Query: 540 CDE-SVLMDLKALL 552
DE L+DL L
Sbjct: 444 PDEIPYLLDLHLFL 457
Score = 29.6 bits (65), Expect = 8.7
Identities = 17/65 (26%), Positives = 31/65 (47%)
Query: 43 RQLLLQKLLQRRRKGAAEEEQQDSGSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARK 102
R L Q + +R+K + G + R ++ + P+GP + L + Q KE+ E
Sbjct: 583 RDLCSQVMRAKRQKDRKAIARFQQGQQGRQEQQEGPVGPAPSRPALQEKQPEKEEEEEAG 642
Query: 103 ESAKE 107
ES ++
Sbjct: 643 ESVED 647
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
Length = 491
Score = 196 bits (499), Expect = 4e-50
Identities = 129/423 (30%), Positives = 223/423 (52%), Gaps = 25/423 (5%)
Query: 154 SMSEERHERVRKKYHILVEGDGIPPPIKSFKEM----KFPAAILRGLKKKGIHHPTPIQI 209
++ +E+ +R K+ I V+G +P PI +F+++ K + +L+ + G PTPIQ+
Sbjct: 26 NLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQM 85
Query: 210 QGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSREL 269
Q IP +L GR+++ A TGSGKTL F++P++M +L +G LII P+REL
Sbjct: 86 QAIPVMLHGRELLASAPTGSGKTLAFSIPILM-------QLKQPANKGFRALIISPTREL 138
Query: 270 ARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQ 329
A Q H L + + A+ K + ++V TP RL+ LL+
Sbjct: 139 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKK-----FDILVTTPNRLIYLLK 193
Query: 330 KKMVSLDIC--RYLALDEADRMID---MGFEGDIRTIFSYFKGQR-QTLLFSATMPKKIQ 383
+ +D+ +L +DE+D++ + GF + +IF + + +FSAT ++
Sbjct: 194 QDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVE 253
Query: 384 NFAKSALVKPVTINVGRAGAASLDVIQEVEYV-KEEAKMVYLLECLQKT-PPPVLIFAEK 441
+ K L +++++G +A V QE+ +V E K++ + E ++K PPVL+F +
Sbjct: 254 QWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQS 313
Query: 442 KADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAI 501
+ L+ +G+ IH + Q++R + +FR GK VL+ T + ++G+DF +
Sbjct: 314 IERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGV 373
Query: 502 QHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPP 561
VINYD P Y+HRIGRTGR+GN G A TF + D+ +L + ++ +A VP
Sbjct: 374 NLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTED-DKPLLRSVANVIQQAGCPVPE 432
Query: 562 VLQ 564
++
Sbjct: 433 YIK 435
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 192 bits (489), Expect = 6e-49
Identities = 119/385 (30%), Positives = 200/385 (51%), Gaps = 20/385 (5%)
Query: 180 IKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPV 239
+ +F +M ++LRG+ G P+ IQ + I + G D+I A +G+GKT F + +
Sbjct: 32 VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISI 91
Query: 240 IMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIG 299
+ Q+ + F + + L++ P+RELA+Q ++ L C CIG
Sbjct: 92 L-----QQLEIEFKETQA---LVLAPTRELAQQIQKVI------LALGDYMGATCHACIG 137
Query: 300 GMSVKEQMETIR-HGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDI 358
G +V+ +M+ ++ H++V TPGR+ D+L ++ +S + LDEAD M+ GF+ I
Sbjct: 138 GTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQI 197
Query: 359 RTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQE--VEYVK 416
IF Q +L SATMP + K + P+ I V + +L+ I++ + +
Sbjct: 198 YEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE-ELTLEGIKQFYINVER 256
Query: 417 EEAKMVYLLECLQK-TPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAI 475
EE K+ L + + T +IF + VD + E + + A+HG DQ+ER +
Sbjct: 257 EEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIM 316
Query: 476 EAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTF 535
FR G VL+ TD+ ++G+D + VINYD+P ENY+HRIGR GR G G+A F
Sbjct: 317 REFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINF 376
Query: 536 INKACDESVLMDLKALLLEAKQKVP 560
+ + D+ +L D++ +++P
Sbjct: 377 VTEE-DKRILRDIETFYNTTVEEMP 400
>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
sapiens]
Length = 600
Score = 192 bits (489), Expect = 6e-49
Identities = 128/362 (35%), Positives = 196/362 (54%), Gaps = 26/362 (7%)
Query: 192 ILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLP 251
+L L++ G + TP+Q IP + +D+ A TGSGKTL F +P++ L +E++L
Sbjct: 20 VLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRREEKL- 78
Query: 252 FSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIR 311
K+ +II P+RELA Q +L ++ + E S L IGG + E +E +
Sbjct: 79 --KKSQVGAIIITPTRELAIQIDEVLSHFTKHFPEFSQ-----ILWIGGRNPGEDVERFK 131
Query: 312 H-GVHMMVATPGRLMDLLQKKMVSLDICR------YLALDEADRMIDMGFEGDIRTIFSY 364
G +++VATPGRL D+ ++K LD+ L LDEADR++DMGFE I TI +
Sbjct: 132 QQGGNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEF 191
Query: 365 FKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQ-----EVEYV--KE 417
QR+T LFSAT ++++N ++ L PV ++V G A+ + E Y+ K
Sbjct: 192 LPKQRRTGLFSATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTPSRLENYYMVCKA 251
Query: 418 EAKMVYLLECLQK-TPPPVLIFAEKKADVDAIHEYL--LLKGVEAVAIHGGKDQEERTKA 474
+ K L+ L+ L+F A V+ + L L+KGV+ + IH GK + +R K
Sbjct: 252 DEKFNQLVHFLRNHKQEKHLVFFSTCACVEYYGKALEVLVKGVKIMCIH-GKMKYKRNKI 310
Query: 475 IEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATT 534
FR+ + +LV TDV ++G+D P + V+ YD P +VHR GRT R G+ G A
Sbjct: 311 FMEFRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALV 370
Query: 535 FI 536
F+
Sbjct: 371 FL 372
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 192 bits (488), Expect = 8e-49
Identities = 123/371 (33%), Positives = 194/371 (52%), Gaps = 19/371 (5%)
Query: 182 SFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIM 241
+F M +LRG+ G P+ IQ + I I+ GRD+I + +G+GKT F++ V+
Sbjct: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98
Query: 242 FCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGM 301
CL+ + R LI+ P+RELA Q LL ++C CIGG
Sbjct: 99 -CLDIQVR-------ETQALILAPTRELAVQIQK------GLLALGDYMNVQCHACIGGT 144
Query: 302 SVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTI 361
+V E + + +G H++ TPGR+ D+++++ + + L LDEAD M++ GF+ I +
Sbjct: 145 NVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDV 204
Query: 362 FSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQE--VEYVKEEA 419
+ Y Q +L SAT+P +I + P+ I V R +L+ I++ V +EE
Sbjct: 205 YRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKR-DELTLEGIKQFFVAVEREEW 263
Query: 420 KMVYLLECLQK-TPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAF 478
K L + T +IF K VD + E + ++HG Q+ER ++ F
Sbjct: 264 KFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEF 323
Query: 479 REGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINK 538
R G VL++TDV ++GLD P + +INYD+P E Y+HRIGR+GR G G+A F+ K
Sbjct: 324 RSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV-K 382
Query: 539 ACDESVLMDLK 549
D +L D++
Sbjct: 383 NDDIRILRDIE 393
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 187 bits (475), Expect = 2e-47
Identities = 117/385 (30%), Positives = 197/385 (51%), Gaps = 20/385 (5%)
Query: 180 IKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPV 239
+ SF +M ++LRG+ G P+ IQ + I + G D+I A +G+GKT F + +
Sbjct: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90
Query: 240 IMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIG 299
+ Q+ L + L++ P+RELA+Q ++ + C CIG
Sbjct: 91 L-----QQIELDLKATQA---LVLAPTRELAQQIQKVVMALGDYMGAS------CHACIG 136
Query: 300 GMSVKEQMETIR-HGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDI 358
G +V+ +++ ++ H++V TPGR+ D+L ++ +S + LDEAD M+ GF+ I
Sbjct: 137 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQI 196
Query: 359 RTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQE--VEYVK 416
IF Q +L SATMP + K + P+ I V + +L+ I++ + +
Sbjct: 197 YDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKE-ELTLEGIRQFYINVER 255
Query: 417 EEAKMVYLLECLQK-TPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAI 475
EE K+ L + + T +IF + VD + E + + A+HG DQ+ER +
Sbjct: 256 EEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIM 315
Query: 476 EAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTF 535
FR G VL+ TD+ ++G+D + VINYD+P ENY+HRIGR GR G G+A
Sbjct: 316 REFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINM 375
Query: 536 INKACDESVLMDLKALLLEAKQKVP 560
+ + D+ L D++ + +++P
Sbjct: 376 VTEE-DKRTLRDIETFYNTSIEEMP 399
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 182 bits (461), Expect = 1e-45
Identities = 132/404 (32%), Positives = 202/404 (50%), Gaps = 42/404 (10%)
Query: 183 FKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMF 242
F E+ + ++ ++ G+ PTP+Q+ IP IL GRD +G A TGSGKT F LP++
Sbjct: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQ- 62
Query: 243 CLEQEKRLPFSKREGPYG---LIICPSRELARQTHGILEYYCRLLQEDSSPL-LRCALCI 298
E PYG L++ P+RELA Q I E + R+L PL L+ + +
Sbjct: 63 ----------KLSEDPYGIFCLVLTPTRELAYQ---IAEQF-RVL---GKPLGLKDCIIV 105
Query: 299 GGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMV-SLDICRYLALDEADRMIDMG---F 354
GGM + Q + H+++ATPGRL D L+ S+ R+L +DEADR+++ G F
Sbjct: 106 GGMDMVAQALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDF 165
Query: 355 EGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEY 414
D+ I + +RQTLLFSAT+ ++ A +P + + Q
Sbjct: 166 TVDLEAILAAVPARRQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLL 225
Query: 415 VKEEAKMVYLLECLQKTPPP-----VLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQE 469
V E+ K YL+ +Q+ ++IF + L VA+H Q+
Sbjct: 226 VPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQK 285
Query: 470 ERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNT 529
ER A+ F+ +L+ATDVAS+GLD P +Q VIN++ P + Y+HR+GRT R+G
Sbjct: 286 ERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQ 345
Query: 530 GIATTFINK-------ACDESVLMDLKALLLEAKQKVPPVLQVL 566
G A T + + A +E + L+ +E + VLQ+L
Sbjct: 346 GQAITLVTQYDIHLVHAIEEQIKKKLEEFSVEEAE----VLQIL 385
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 181 bits (460), Expect = 1e-45
Identities = 137/442 (30%), Positives = 215/442 (48%), Gaps = 42/442 (9%)
Query: 143 KTSWTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIH 202
K W R +S + +E++ I F + L+GL++
Sbjct: 43 KPEWQVERESISRLMQNYEKINVN------------EITRFSDFPLSKKTLKGLQEAQYR 90
Query: 203 HPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLI 262
T IQ Q I L G+D++G A TGSGKTL F +PV LE RL ++ +G LI
Sbjct: 91 LVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPV----LEALYRLQWTSTDGLGVLI 146
Query: 263 ICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPG 322
I P+RELA QT +L + D S L IGG +K + E I + ++++V TPG
Sbjct: 147 ISPTRELAYQTFEVLRKVGK--NHDFS----AGLIIGGKDLKHEAERINN-INILVCTPG 199
Query: 323 RLMDLLQKKMV--SLDICRYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPK 380
RL+ + + + + D+ + L LDEADR++DMGF + + +RQTLLFSAT K
Sbjct: 200 RLLQHMDETVSFHATDL-QMLVLDEADRILDMGFADTMNAVIENLPKKRQTLLFSATQTK 258
Query: 381 KIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYV----KEEAKMVYLLECLQKTPPPVL 436
+++ A+ +L P + V S E Y+ +++ ++Y ++
Sbjct: 259 SVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLYSFLRSHLKKKSIV 318
Query: 437 IFAEKKADVDAIHEYL--LLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASK 494
F+ K +V ++ L GV +A+HG + Q R + F + VL ATD+A++
Sbjct: 319 FFSSCK-EVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAAR 377
Query: 495 GLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLE 554
GLDFPA+ V+ +D PE+ Y+HR GRT R G A + L KA++ +
Sbjct: 378 GLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLIL--------LPSEKAMVQQ 429
Query: 555 AKQKVPPVLQVLHCGDESMLDI 576
QK PV ++ E ++D+
Sbjct: 430 LLQKKVPVKEI-KINPEKLIDV 450
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 181 bits (460), Expect = 1e-45
Identities = 114/341 (33%), Positives = 190/341 (55%), Gaps = 15/341 (4%)
Query: 193 LRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPF 252
L+ +K+ G + T IQ + I +L GRD++ A TGSGKTL F +P + + +L F
Sbjct: 191 LKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIV----KLRF 246
Query: 253 SKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRH 312
R G LI+ P+RELA QT G+L+ + + L +GG + + + + +
Sbjct: 247 MPRNGTGVLILSPTRELAMQTFGVLKELM------THHVHTYGLIMGGSNRSAEAQKLGN 300
Query: 313 GVHMMVATPGRLMDLLQKKMVSL-DICRYLALDEADRMIDMGFEGDIRTIFSYFKGQRQT 371
G++++VATPGRL+D +Q + + L +DEADR++D+GFE +++ I +RQT
Sbjct: 301 GINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQT 360
Query: 372 LLFSATMPKKIQNFAKSALVK-PVTINVGRAGA-ASLDVIQEVEYV-KEEAKMVYLLECL 428
+LFSAT +K+++ A+ +L K P+ + V A A++D +++ V E + + L L
Sbjct: 361 MLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFL 420
Query: 429 QKT-PPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLV 487
+K +++F V +E L + +AIHG + Q +RT F L+
Sbjct: 421 KKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLL 480
Query: 488 ATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGN 528
TDVA++GLD P + ++ YD P++ + Y+HR+GRT R N
Sbjct: 481 CTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLN 521
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,720,642
Number of Sequences: 37866
Number of extensions: 1179876
Number of successful extensions: 6397
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 181
Number of HSP's that attempted gapping in prelim test: 5524
Number of HSP's gapped (non-prelim): 783
length of query: 622
length of database: 18,247,518
effective HSP length: 108
effective length of query: 514
effective length of database: 14,157,990
effective search space: 7277206860
effective search space used: 7277206860
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.