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Search of human proteins with 21071030
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21071030 alpha 1B-glycoprotein precursor [Homo sapiens]
(495 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21071030 alpha 1B-glycoprotein precursor [Homo sapiens] 1016 0.0
gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo... 184 1e-46
gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A... 117 2e-26
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 116 5e-26
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 116 5e-26
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 114 2e-25
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 114 2e-25
gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m... 109 7e-24
gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A (... 107 2e-23
gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B... 106 6e-23
gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, ... 105 1e-22
gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A... 103 5e-22
gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A (... 103 5e-22
gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 100 5e-21
gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 100 5e-21
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 99 7e-21
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 99 7e-21
gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A ... 91 2e-18
gi|208879429 hypothetical LOC441864 [Homo sapiens] 83 7e-16
gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B... 80 3e-15
gi|46488946 killer cell immunoglobulin-like receptor, three doma... 77 5e-14
gi|32895361 leukocyte immunoglobulin-like receptor subfamily A m... 77 5e-14
gi|32490553 leukocyte immunoglobulin-like receptor subfamily A m... 77 5e-14
gi|45580719 osteoclast-associated receptor isoform 1 [Homo sapiens] 75 1e-13
gi|134268644 killer cell immunoglobulin-like receptor, three dom... 72 9e-13
gi|19557668 osteoclast-associated receptor isoform 4 [Homo sapiens] 72 1e-12
gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B... 72 2e-12
gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B... 72 2e-12
gi|45580713 osteoclast-associated receptor isoform 3 [Homo sapiens] 71 2e-12
gi|19557664 osteoclast-associated receptor isoform 5 [Homo sapiens] 70 6e-12
>gi|21071030 alpha 1B-glycoprotein precursor [Homo sapiens]
Length = 495
Score = 1016 bits (2626), Expect = 0.0
Identities = 495/495 (100%), Positives = 495/495 (100%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL
Sbjct: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
Query: 61 FKNGVAQEPVHLDSPAIKHQFLLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLPAPW 120
FKNGVAQEPVHLDSPAIKHQFLLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLPAPW
Sbjct: 61 FKNGVAQEPVHLDSPAIKHQFLLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLPAPW 120
Query: 121 LSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPVHQPGNY 180
LSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPVHQPGNY
Sbjct: 121 LSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPVHQPGNY 180
Query: 181 SCSYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVD 240
SCSYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVD
Sbjct: 181 SCSYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVD 240
Query: 241 FQLRRGEKELLVPRSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELI 300
FQLRRGEKELLVPRSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELI
Sbjct: 241 FQLRRGEKELLVPRSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELI 300
Query: 301 LSDETLPAPEFSPEPESGRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFE 360
LSDETLPAPEFSPEPESGRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFE
Sbjct: 301 LSDETLPAPEFSPEPESGRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFE 360
Query: 361 LHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAV 420
LHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAV
Sbjct: 361 LHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAV 420
Query: 421 LRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTF 480
LRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTF
Sbjct: 421 LRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTF 480
Query: 481 ESELSDPVELLVAES 495
ESELSDPVELLVAES
Sbjct: 481 ESELSDPVELLVAES 495
>gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo
sapiens]
Length = 1336
Score = 184 bits (468), Expect = 1e-46
Identities = 159/511 (31%), Positives = 236/511 (46%), Gaps = 31/511 (6%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAA--IFYETQPSLWAESESLLKPLANVTLTCQAHL-ETPD 57
M +V LL G+ G + E + +P LWAE+ L P N+TL C++ T +
Sbjct: 562 MLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKE 621
Query: 58 FQLFKNGVAQEPVHLDSPAIKHQFLLTGDTQ---GRYRCRSGLSTGWTQLSKLLELTGPK 114
F L K+G S ++ F L TQ G Y C S ++ S+ LEL G
Sbjct: 622 FVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTD 681
Query: 115 SLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPV 174
LP P +S +P G + C+G L G+ F L +EG+ E ++ A EA F +
Sbjct: 682 ILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGA-VGREAFFTI 737
Query: 175 HQ-----PGNYSCSYRTDGEG-ALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKV 228
+ GNYSC T+ SEPS + + P P +S V+ PG +V
Sbjct: 738 QRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTW--ASPVVTPGARV 795
Query: 229 TLTCVAPLSGVDFQLRRGEKELL-VPRSSTSP--DRIFFHLNAVALGDGGHYTCRYRLHD 285
T C P + F L + E+ RS SP F + +V +GDGG+Y+CRY
Sbjct: 796 TFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY--- 852
Query: 286 NQNGWSGDSAPVELILSDETLPAPEFSPEPE----SGRALRLRCLAPLEGARFALVREDR 341
+ + WS S PVEL+++ E P P +P G+++ LRC +G RFAL++E
Sbjct: 853 DFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE-- 909
Query: 342 GGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPP 401
G +F+S +G A F LH + DS NYSC+Y + GS S L + V P
Sbjct: 910 GAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFP 969
Query: 402 RPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVG 461
+P L A S V G++ L C GP+ V + L +EGE +++ + + +
Sbjct: 970 KPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNIS 1029
Query: 462 PQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
G Y C Y + + + S+ +ELLV
Sbjct: 1030 GTSMGRYSCCYHPDWTSSIKIQPSNTLELLV 1060
Score = 152 bits (383), Expect = 9e-37
Identities = 151/480 (31%), Positives = 209/480 (43%), Gaps = 32/480 (6%)
Query: 32 WAESESLLKPLANVTLTCQAHLETPDFQLFKNG--VAQEPVHLDSP-AIKHQFLLT---- 84
WA ++ P A VT C + F L+K+G +A SP A FL+
Sbjct: 784 WASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGI 841
Query: 85 GDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLR 144
GD G Y CR + W++ S +EL + P P L P + PG C+G +
Sbjct: 842 GDG-GNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQ 900
Query: 145 GVTFLLRREGDHEFLEVPEAQEDVEATFPVH-----QPGNYSCSY-RTDGEGALSEPSAT 198
G+ F L +EG H L+ + A F +H GNYSC Y T S S
Sbjct: 901 GMRFALLQEGAHVPLQFRSVSGN-SADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMP 959
Query: 199 VTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRR-GEKELLVPRSST 257
+ I P P L E S V+ G VTL C P+ GV + L + GE + ST
Sbjct: 960 LMIWVTDTFPKPWLF--AEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGST 1017
Query: 258 SPDRIFFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP-- 315
S D F N ++ G Y+C Y + S +EL+++ LP P +P
Sbjct: 1018 SNDGAFPITN-ISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-LLPKPSLLAQPGP 1075
Query: 316 --ESGRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFELHNISVADSANYS 373
G + L+C L + F L++E G + Q P+G A F + + DS YS
Sbjct: 1076 MVAPGENMTLQCQGELPDSTFVLLKE--GAQEPLEQQRPSGYRADFWMPAVRGEDSGIYS 1133
Query: 374 CVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFE 433
CVY PF S S+ LE+ V PP+P L A S G+D L+C GP+P V F
Sbjct: 1134 CVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFV 1193
Query: 434 LLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLVA 493
L +GE +A + G + + V + GNY C YR SE SDP+EL+ A
Sbjct: 1194 LEHDGE-EAPQQFSEDG---DFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGA 1249
Score = 141 bits (356), Expect = 1e-33
Identities = 132/469 (28%), Positives = 196/469 (41%), Gaps = 32/469 (6%)
Query: 47 LTCQAHLETPDFQLFKNGVAQEPVHLDSPAIKHQFL----LTGDTQGRYRCRSGLSTG-- 100
L C+ L F L+K G QEPV + F + +G Y CR+
Sbjct: 701 LRCKGWLAGMGFALYKEG-EQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPF 759
Query: 101 -WTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREG----- 154
W++ S+ LEL + P P+ +TPG + T C + ++F+L ++G
Sbjct: 760 KWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIAS 819
Query: 155 -DHEFLEV-PEAQEDVEATFPVHQPGNYSCSYRTDGEGALSEPSATVTIEELAAPPPPVL 212
D + A + + + GNYSC Y SEPS V + P P L
Sbjct: 820 SDRSWASPGASAAHFLIISVGIGDGGNYSCRYY--DFSIWSEPSDPVELVVTEFYPKPTL 877
Query: 213 MHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIFFHLNAVALG 272
+ + V+ PG V L C G+ F L + + + S S + F L+ V
Sbjct: 878 L--AQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAE 935
Query: 273 DGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEPES----GRALRLRCLAP 328
D G+Y+C Y N S S P+ + ++D T P P EP S G+ + L C P
Sbjct: 936 DSGNYSCIYYETTMSNRGSYLSMPLMIWVTD-TFPKPWLFAEPSSVVPMGQNVTLWCRGP 994
Query: 329 LEGARFALVREDRGGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGS-- 386
+ G + L +E G + + F + NIS YSC Y P + S
Sbjct: 995 VHGVGYILHKE--GEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCY---HPDWTSSIK 1049
Query: 387 -APSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKT 445
PS LEL V G P+P L A V G + L+C+G +PD TF LL+EG + ++
Sbjct: 1050 IQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQ 1109
Query: 446 VRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLVAE 494
R G A+ + V + +G Y C Y S SD +E+ V +
Sbjct: 1110 QRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTD 1158
Score = 136 bits (343), Expect = 4e-32
Identities = 132/509 (25%), Positives = 201/509 (39%), Gaps = 33/509 (6%)
Query: 2 SMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLE-TPDFQL 60
+ML F +L + +I + QP LW ES P N+TL C++ + F L
Sbjct: 11 TMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRSPSRISSKFLL 70
Query: 61 FKNGVAQEPVHLDSPAIKHQFL---LTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLP 117
K+ + + FL LT G YRC TGW++ SK+LEL P LP
Sbjct: 71 LKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLP 130
Query: 118 APWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPV--- 174
P + + PG +C G L+ + F+L +EG E ++ + A F +
Sbjct: 131 KPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-QVPTGTMAIFSIDNL 189
Query: 175 --HQPGNYSCSYRTDGEGAL-SEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLT 231
G Y C L SEPS + + P P L H ++ PG + L
Sbjct: 190 TPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAH--PGPIMAPGESLNLR 247
Query: 232 CVAPLSGVDFQLRRGEK-ELLVPRSSTSPDRIFFHLNAVALGDGGHYTCRY--------R 282
C P+ G+ F L R E E T + F ++ + D GHY C Y
Sbjct: 248 CQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYDASYRGSL 307
Query: 283 LHDNQNGWSGDSAPVELILSDETLPAPEFSPEPESGRALRLRCLAPLEGARFALVREDRG 342
L D W D+ P +L+ S + G+ + LRC P++G AL ++
Sbjct: 308 LSDVLKIWVTDTFPKTWLLARP-------SAVVQMGQNVSLRCRGPVDGVGLALYKKGED 360
Query: 343 GRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPR 402
+ F L+N++ +D+ YSC Y+ +EL V PP+
Sbjct: 361 KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPK 420
Query: 403 PQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGP 462
P L A S G+ L+C P + F L E + +T + + + V
Sbjct: 421 PSLSAWPSTVFKLGKAITLQCRVSHPVLEFSL----EWEERETFQKFSVNGDFIISNVDG 476
Query: 463 QHAGNYRCRYRSWVPHTFESELSDPVELL 491
+ G Y C YR S S+P++L+
Sbjct: 477 KGTGTYSCSYRVETHPNIWSHRSEPLKLM 505
Score = 121 bits (304), Expect = 1e-27
Identities = 103/358 (28%), Positives = 157/358 (43%), Gaps = 22/358 (6%)
Query: 148 FLLRREGDHEFLEVPEAQEDVEATFPV-----HQPGNYSCSYRTDGEGALSEPSATVTIE 202
F+L ++G P A E V A FP+ G+Y C + E A+SEPS + +
Sbjct: 622 FVLLKDGTGWIATRP-ASEQVRAAFPLGALTQSHTGSYHC--HSWEEMAVSEPSEALELV 678
Query: 203 ELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRI 262
P PV+ S+ G ++ L C L+G+ F L + ++ V +
Sbjct: 679 GTDILPKPVI-----SASPTIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREA 733
Query: 263 FFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEF----SPEPESG 318
FF + + D G+Y+CR WS S P+EL++ E P P F SP G
Sbjct: 734 FFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIK-EMYPKPFFKTWASPVVTPG 792
Query: 319 RALRLRCLAPLEGARFALVREDRGGRRVHR-FQSPAGTEALFELHNISVADSANYSCVYV 377
+ C P + F L ++ R + SP + A F + ++ + D NYSC Y
Sbjct: 793 ARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY 852
Query: 378 DLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLRE 437
D S PS+ +EL V P+P L A V G+ +LRC+G + F LL+E
Sbjct: 853 DFSI---WSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE 909
Query: 438 GETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLVAES 495
G ++ G +A+ L VG + +GNY C Y S LS P+ + V ++
Sbjct: 910 GAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDT 967
Score = 70.9 bits (172), Expect = 3e-12
Identities = 61/188 (32%), Positives = 83/188 (44%), Gaps = 9/188 (4%)
Query: 28 QPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQEPVHLDSPA-IKHQF---LL 83
+PSL A+ ++ P N+TL CQ L F L K G AQEP+ P+ + F +
Sbjct: 1066 KPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG-AQEPLEQQRPSGYRADFWMPAV 1124
Query: 84 TGDTQGRYRCRSGLST---GWTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCR 140
G+ G Y C L + + S LE+ P P LS P + G T CR
Sbjct: 1125 RGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCR 1184
Query: 141 GVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPVHQPGNYSCSYRTDGEGAL-SEPSATV 199
G L GV F+L +G+ + E + V GNYSCSYR + SEPS +
Sbjct: 1185 GPLPGVEFVLEHDGEEAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPL 1244
Query: 200 TIEELAAP 207
+ A P
Sbjct: 1245 ELVGAAGP 1252
Score = 52.4 bits (124), Expect = 9e-07
Identities = 39/135 (28%), Positives = 61/135 (45%), Gaps = 3/135 (2%)
Query: 359 FELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRD 418
F + ++ +++ Y C Y G S PS+ LEL G P+P L G +
Sbjct: 91 FLIGALTESNAGLYRCCYWK---ETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCN 147
Query: 419 AVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPH 478
+ C G + D+ F L +EG + V G A + + P+ G Y CR +
Sbjct: 148 VNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLP 207
Query: 479 TFESELSDPVELLVA 493
T SE S+P++L+VA
Sbjct: 208 TLWSEPSNPLKLVVA 222
>gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A,
member 6 [Homo sapiens]
Length = 481
Score = 117 bits (294), Expect = 2e-26
Identities = 122/426 (28%), Positives = 183/426 (42%), Gaps = 34/426 (7%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ + LL G++ GP T +P+LWAE S++ + VT+ CQ LE ++QL
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQL 60
Query: 61 FKNGVAQEPVHLDS---PAIKHQFLLTGDTQ---GRYRCRSGLSTGWTQLSKLLELTGPK 114
K G + EP+ ++ P K +F + TQ GRYRC S GW++ S LEL
Sbjct: 61 DKEG-SPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTG 119
Query: 115 SLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQE----DVEA 170
P LS P + G T C F+L +EG+H+ ++Q+ +A
Sbjct: 120 FYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQA 179
Query: 171 TFPV-----HQPGNYSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHP 224
FPV ++C Y T+ S PS + I P L+ VL P
Sbjct: 180 LFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLL--TLQGPVLAP 237
Query: 225 GNKVTLTCVAPLSGVDFQL-RRGEKELLVPRSSTSP----DRIFFHLNAVALGDGGHYTC 279
G +TL C + + F L + GE++ L R P + F L V+ GG Y C
Sbjct: 238 GQSLTLQCGSDVGYDRFVLYKEGERDFL-QRPGQQPQAGLSQANFTLGPVSPSHGGQYRC 296
Query: 280 RYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEGARFA 335
Y H+ + WS S P+ ++++ + S +P SG + L C + F
Sbjct: 297 -YGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFL 355
Query: 336 LVREDRGGRRVHRFQSPAGT---EALFELHNISVADSANYSCVYVDLKPPFGGSAPSERL 392
L +E + R +S G +A F + ++ A + Y C P S PSE L
Sbjct: 356 LTKEGAAHPPL-RLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPL 414
Query: 393 ELHVDG 398
EL V G
Sbjct: 415 ELMVSG 420
Score = 86.3 bits (212), Expect = 6e-17
Identities = 90/310 (29%), Positives = 135/310 (43%), Gaps = 42/310 (13%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQL-RRGEKELLVPRSSTSP-DRIFFH 265
P P L E V+ G+ VT+ C L ++QL + G E L + P ++ F
Sbjct: 27 PKPTLW--AEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPEPLDRNNPLEPKNKARFS 84
Query: 266 LNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSD----ETLPAPEFSPEPESGRAL 321
+ ++ G Y C Y + GWS S P+EL+++ TL A SP SG +
Sbjct: 85 IPSMTQHHAGRYRCHYY---SSAGWSEPSDPLELVMTGFYNKPTLSALP-SPVVASGGNM 140
Query: 322 RLRCLAPLEGARFALVREDR-------GGRRVHRFQSPAGTEALFELHNISVADSANYSC 374
LRC + F L++E +++H G +ALF + ++ + ++C
Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHS----GGFQALFPVGPVTPSHRWRFTC 196
Query: 375 VYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLA-GRDAVLRCEGPIPDVTFE 433
Y P S PS+ LE+ G +P L T G VLA G+ L+C + F
Sbjct: 197 YYYYTNTPRVWSHPSDPLEILPSGVSRKPSL-LTLQGPVLAPGQSLTLQCGSDVGYDRFV 255
Query: 434 LLREGETKAVKTVRTPG-------AAANLELIFVGPQHAGNYRCRYRSWVPHTFESEL-- 484
L +EGE ++ PG + AN L V P H G YRC + H SE
Sbjct: 256 LYKEGER---DFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRC----YGAHNLSSEWSA 308
Query: 485 -SDPVELLVA 493
SDP+ +L+A
Sbjct: 309 PSDPLNILMA 318
Score = 43.5 bits (101), Expect = 4e-04
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAV--KTVRTPGAAANL 455
GP P+P L A + G + C+G + ++L +EG + + P A
Sbjct: 24 GPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPEPLDRNNPLEPKNKARF 83
Query: 456 ELIFVGPQHAGNYRCRYRS---WVPHTFESELSDPVELLV 492
+ + HAG YRC Y S W SE SDP+EL++
Sbjct: 84 SIPSMTQHHAGRYRCHYYSSAGW------SEPSDPLELVM 117
>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 1 [Homo sapiens]
Length = 632
Score = 116 bits (290), Expect = 5e-26
Identities = 118/426 (27%), Positives = 185/426 (43%), Gaps = 34/426 (7%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ + LL G++ GP T +P+LWAE S++ + VT+ CQ E +++L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 61 FKNGVAQEPVHLDS---PAIKHQFLLTGDTQ---GRYRCRSGLSTGWTQLSKLLELTGPK 114
K G + EP+ ++ P K +F + T+ GRYRC S GW++ S LE+
Sbjct: 61 HKEG-SPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTG 119
Query: 115 SLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQE----DVEA 170
+ P LS P + G T C F+L +EG+H+ ++Q+ +A
Sbjct: 120 AYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQA 179
Query: 171 TFPV-----HQPGNYSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHP 224
FPV ++C Y T+ S PS + I P L+ VL P
Sbjct: 180 LFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLL--TLQGPVLAP 237
Query: 225 GNKVTLTCVAPLSGVDFQL-RRGEKELLVPRSSTSP----DRIFFHLNAVALGDGGHYTC 279
G +TL C + + F L + GE++ L R P + F L V+ +GG Y C
Sbjct: 238 GQSLTLQCGSDVGYNRFVLYKEGERDFL-QRPGQQPQAGLSQANFTLGPVSPSNGGQYRC 296
Query: 280 RYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEGARFA 335
Y H+ + WS S P+ ++++ + S +P SG + L C + + F
Sbjct: 297 -YGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFL 355
Query: 336 LVREDRGGRRVHRFQSPAGT---EALFELHNISVADSANYSCVYVDLKPPFGGSAPSERL 392
L +E + R +S G +A F + ++ A + Y C P S PSE L
Sbjct: 356 LTKEGAAHPPL-RLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPL 414
Query: 393 ELHVDG 398
EL V G
Sbjct: 415 ELVVSG 420
Score = 80.9 bits (198), Expect = 2e-15
Identities = 87/310 (28%), Positives = 135/310 (43%), Gaps = 42/310 (13%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRR-GEKELLVPRSSTSP-DRIFFH 265
P P L E V+ G+ VT+ C +++L + G E L + P ++ F
Sbjct: 27 PKPTLW--AEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFS 84
Query: 266 LNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELIL----SDETLPAPEFSPEPESGRAL 321
+ ++ G Y C Y + GWS S P+E+++ S TL A SP SG +
Sbjct: 85 IPSMTEHHAGRYRCHYY---SSAGWSEPSDPLEMVMTGAYSKPTLSALP-SPVVASGGNM 140
Query: 322 RLRCLAPLEGARFALVREDR-------GGRRVHRFQSPAGTEALFELHNISVADSANYSC 374
LRC + F L++E +++H G +ALF + ++ + ++C
Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHS----RGFQALFPVGPVTPSHRWRFTC 196
Query: 375 VYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLA-GRDAVLRCEGPIPDVTFE 433
Y P+ S PS+ LE+ G +P L T G VLA G+ L+C + F
Sbjct: 197 YYYYTNTPWVWSHPSDPLEILPSGVSRKPSL-LTLQGPVLAPGQSLTLQCGSDVGYNRFV 255
Query: 434 LLREGETKAVKTVRTPG-------AAANLELIFVGPQHAGNYRCRYRSWVPHTFESEL-- 484
L +EGE ++ PG + AN L V P + G YRC + H SE
Sbjct: 256 LYKEGER---DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC----YGAHNLSSEWSA 308
Query: 485 -SDPVELLVA 493
SDP+ +L+A
Sbjct: 309 PSDPLNILMA 318
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 11/100 (11%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAV--KTVRTPGAAANL 455
GP P+P L A + G + C+G + L +EG + + P A
Sbjct: 24 GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARF 83
Query: 456 ELIFVGPQHAGNYRCRYRS---WVPHTFESELSDPVELLV 492
+ + HAG YRC Y S W SE SDP+E+++
Sbjct: 84 SIPSMTEHHAGRYRCHYYSSAGW------SEPSDPLEMVM 117
>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 2 [Homo sapiens]
Length = 631
Score = 116 bits (290), Expect = 5e-26
Identities = 118/426 (27%), Positives = 185/426 (43%), Gaps = 34/426 (7%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ + LL G++ GP T +P+LWAE S++ + VT+ CQ E +++L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 61 FKNGVAQEPVHLDS---PAIKHQFLLTGDTQ---GRYRCRSGLSTGWTQLSKLLELTGPK 114
K G + EP+ ++ P K +F + T+ GRYRC S GW++ S LE+
Sbjct: 61 HKEG-SPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTG 119
Query: 115 SLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQE----DVEA 170
+ P LS P + G T C F+L +EG+H+ ++Q+ +A
Sbjct: 120 AYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQA 179
Query: 171 TFPV-----HQPGNYSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHP 224
FPV ++C Y T+ S PS + I P L+ VL P
Sbjct: 180 LFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLL--TLQGPVLAP 237
Query: 225 GNKVTLTCVAPLSGVDFQL-RRGEKELLVPRSSTSP----DRIFFHLNAVALGDGGHYTC 279
G +TL C + + F L + GE++ L R P + F L V+ +GG Y C
Sbjct: 238 GQSLTLQCGSDVGYNRFVLYKEGERDFL-QRPGQQPQAGLSQANFTLGPVSPSNGGQYRC 296
Query: 280 RYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEGARFA 335
Y H+ + WS S P+ ++++ + S +P SG + L C + + F
Sbjct: 297 -YGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFL 355
Query: 336 LVREDRGGRRVHRFQSPAGT---EALFELHNISVADSANYSCVYVDLKPPFGGSAPSERL 392
L +E + R +S G +A F + ++ A + Y C P S PSE L
Sbjct: 356 LTKEGAAHPPL-RLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPL 414
Query: 393 ELHVDG 398
EL V G
Sbjct: 415 ELVVSG 420
Score = 80.9 bits (198), Expect = 2e-15
Identities = 87/310 (28%), Positives = 135/310 (43%), Gaps = 42/310 (13%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRR-GEKELLVPRSSTSP-DRIFFH 265
P P L E V+ G+ VT+ C +++L + G E L + P ++ F
Sbjct: 27 PKPTLW--AEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFS 84
Query: 266 LNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELIL----SDETLPAPEFSPEPESGRAL 321
+ ++ G Y C Y + GWS S P+E+++ S TL A SP SG +
Sbjct: 85 IPSMTEHHAGRYRCHYY---SSAGWSEPSDPLEMVMTGAYSKPTLSALP-SPVVASGGNM 140
Query: 322 RLRCLAPLEGARFALVREDR-------GGRRVHRFQSPAGTEALFELHNISVADSANYSC 374
LRC + F L++E +++H G +ALF + ++ + ++C
Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHS----RGFQALFPVGPVTPSHRWRFTC 196
Query: 375 VYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLA-GRDAVLRCEGPIPDVTFE 433
Y P+ S PS+ LE+ G +P L T G VLA G+ L+C + F
Sbjct: 197 YYYYTNTPWVWSHPSDPLEILPSGVSRKPSL-LTLQGPVLAPGQSLTLQCGSDVGYNRFV 255
Query: 434 LLREGETKAVKTVRTPG-------AAANLELIFVGPQHAGNYRCRYRSWVPHTFESEL-- 484
L +EGE ++ PG + AN L V P + G YRC + H SE
Sbjct: 256 LYKEGER---DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC----YGAHNLSSEWSA 308
Query: 485 -SDPVELLVA 493
SDP+ +L+A
Sbjct: 309 PSDPLNILMA 318
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 11/100 (11%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAV--KTVRTPGAAANL 455
GP P+P L A + G + C+G + L +EG + + P A
Sbjct: 24 GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARF 83
Query: 456 ELIFVGPQHAGNYRCRYRS---WVPHTFESELSDPVELLV 492
+ + HAG YRC Y S W SE SDP+E+++
Sbjct: 84 SIPSMTEHHAGRYRCHYYSSAGW------SEPSDPLEMVM 117
>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 1 [Homo sapiens]
Length = 598
Score = 114 bits (285), Expect = 2e-25
Identities = 112/429 (26%), Positives = 187/429 (43%), Gaps = 38/429 (8%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ +V L+ G++ GP T +P+LWAE +S++ + VTL+CQ LE +++L
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 61 FKNGVAQEPVHLDSPAIK-----HQFLLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKS 115
++ + + P + H +T + GRY C+ W++LS L L +
Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGA 120
Query: 116 LPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEV----PEAQEDVEAT 171
P P LS P +T G + T C + F+L +EG+ E + P A+ A
Sbjct: 121 YPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAI 180
Query: 172 FPV-----HQPGNYSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPG 225
F V ++ ++ C Y + S PS + + P L + V+ PG
Sbjct: 181 FSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSL--SVQPGPVVAPG 238
Query: 226 NKVTLTCVAPLSGVDFQL-RRGEKEL-----LVPRSSTSPDRIFFHLNAVALGDGGHYTC 279
+TL CV+ + F L + GE++L P++ S + F L V+ GG Y C
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLS--QANFTLGPVSRSYGGQYRC 296
Query: 280 RYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEGARFA 335
Y H+ + S S P++++++ + P S +P SG + L C + + F
Sbjct: 297 -YGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFL 355
Query: 336 LVREDRGG-----RRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSE 390
L + R +H + +A F + ++ A + Y C P+ S PSE
Sbjct: 356 LTKAGAADAPLRLRSIHEYPK---YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSE 412
Query: 391 RLELHVDGP 399
LEL V GP
Sbjct: 413 PLELVVSGP 421
Score = 84.0 bits (206), Expect = 3e-16
Identities = 84/305 (27%), Positives = 132/305 (43%), Gaps = 34/305 (11%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIF---F 264
P P L E V+ G+ VTL+C L +++L R EK+ + P+ + F
Sbjct: 27 PKPTLW--AEPDSVITQGSPVTLSCQGSLEAQEYRLYR-EKKSASWITRIRPELVKNGQF 83
Query: 265 HLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEPE----SGRA 320
H+ ++ G Y C+Y ++ WS S P+ L+++ P P S +P SG
Sbjct: 84 HIPSITWEHTGRYGCQYY---SRARWSELSDPLVLVMTG-AYPKPTLSAQPSPVVTSGGR 139
Query: 321 LRLRCLAPLEGARFALVREDRGGRRVH------RFQSPAGTEALFELHNISVADSANYSC 374
+ L+C + + F L +E G H + + + A+F + +S ++ C
Sbjct: 140 VTLQCESQVAFGGFILCKE---GEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRC 196
Query: 375 VYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFEL 434
DL P+ S+PS+ LEL V G +P L V G L+C + F L
Sbjct: 197 YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVL 256
Query: 435 LREGETKAVKTV-RTPGAA---ANLELIFVGPQHAGNYRCRYRSWVPHTFESEL---SDP 487
+EGE + R P A AN L V + G YRC + H SE SDP
Sbjct: 257 YKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC----YGAHNLSSECSAPSDP 312
Query: 488 VELLV 492
+++L+
Sbjct: 313 LDILI 317
Score = 52.0 bits (123), Expect = 1e-06
Identities = 79/330 (23%), Positives = 129/330 (39%), Gaps = 35/330 (10%)
Query: 15 WGPVTEAAIFYET----QPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQEPV 70
W +++ + T +P+L A+ ++ VTL C++ + F L K G + P
Sbjct: 106 WSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQ 165
Query: 71 HLDSP--------AIKHQFLLTGDTQGRYRCRS---GLSTGWTQLSKLLELTGPKSLPAP 119
L+S AI ++ + + +RC W+ S LLEL P P
Sbjct: 166 CLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKP 225
Query: 120 WLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDV---EATF---P 173
LS+ P + PG T C + F+L +EG+ + ++P Q +A F P
Sbjct: 226 SLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGP 285
Query: 174 VHQP--GNYSCSYRTDGEGALSEPS--ATVTIEELAAPPPPVLMHHGESSQVLHPGNKVT 229
V + G Y C + S PS + I P + + G + + G VT
Sbjct: 286 VSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPT---VASGENVT 342
Query: 230 LTCVAPLSGVDFQLRRG---EKELLVPRSSTSPD-RIFFHLNAVALGDGGHYTCRYRLHD 285
L C + F L + + L + P + F ++ V G Y C L+
Sbjct: 343 LLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNS 402
Query: 286 NQNGWSGDSAPVELILSDETLPAPEFSPEP 315
+ S S P+EL++S P+ SP P
Sbjct: 403 DPYLLSHPSEPLELVVSG---PSMGSSPPP 429
Score = 39.3 bits (90), Expect = 0.008
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAAN--L 455
G P+P L A + G L C+G + + L RE ++ + T P N
Sbjct: 24 GTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQF 83
Query: 456 ELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
+ + +H G Y C+Y S SELSDP+ L++
Sbjct: 84 HIPSITWEHTGRYGCQYYS---RARWSELSDPLVLVM 117
>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 2 [Homo sapiens]
Length = 597
Score = 114 bits (285), Expect = 2e-25
Identities = 112/429 (26%), Positives = 187/429 (43%), Gaps = 38/429 (8%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ +V L+ G++ GP T +P+LWAE +S++ + VTL+CQ LE +++L
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 61 FKNGVAQEPVHLDSPAIK-----HQFLLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKS 115
++ + + P + H +T + GRY C+ W++LS L L +
Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGA 120
Query: 116 LPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEV----PEAQEDVEAT 171
P P LS P +T G + T C + F+L +EG+ E + P A+ A
Sbjct: 121 YPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAI 180
Query: 172 FPV-----HQPGNYSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPG 225
F V ++ ++ C Y + S PS + + P L + V+ PG
Sbjct: 181 FSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSL--SVQPGPVVAPG 238
Query: 226 NKVTLTCVAPLSGVDFQL-RRGEKEL-----LVPRSSTSPDRIFFHLNAVALGDGGHYTC 279
+TL CV+ + F L + GE++L P++ S + F L V+ GG Y C
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLS--QANFTLGPVSRSYGGQYRC 296
Query: 280 RYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEGARFA 335
Y H+ + S S P++++++ + P S +P SG + L C + + F
Sbjct: 297 -YGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFL 355
Query: 336 LVREDRGG-----RRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSE 390
L + R +H + +A F + ++ A + Y C P+ S PSE
Sbjct: 356 LTKAGAADAPLRLRSIHEYPK---YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSE 412
Query: 391 RLELHVDGP 399
LEL V GP
Sbjct: 413 PLELVVSGP 421
Score = 84.0 bits (206), Expect = 3e-16
Identities = 84/305 (27%), Positives = 132/305 (43%), Gaps = 34/305 (11%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIF---F 264
P P L E V+ G+ VTL+C L +++L R EK+ + P+ + F
Sbjct: 27 PKPTLW--AEPDSVITQGSPVTLSCQGSLEAQEYRLYR-EKKSASWITRIRPELVKNGQF 83
Query: 265 HLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEPE----SGRA 320
H+ ++ G Y C+Y ++ WS S P+ L+++ P P S +P SG
Sbjct: 84 HIPSITWEHTGRYGCQYY---SRARWSELSDPLVLVMTG-AYPKPTLSAQPSPVVTSGGR 139
Query: 321 LRLRCLAPLEGARFALVREDRGGRRVH------RFQSPAGTEALFELHNISVADSANYSC 374
+ L+C + + F L +E G H + + + A+F + +S ++ C
Sbjct: 140 VTLQCESQVAFGGFILCKE---GEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRC 196
Query: 375 VYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFEL 434
DL P+ S+PS+ LEL V G +P L V G L+C + F L
Sbjct: 197 YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVL 256
Query: 435 LREGETKAVKTV-RTPGAA---ANLELIFVGPQHAGNYRCRYRSWVPHTFESEL---SDP 487
+EGE + R P A AN L V + G YRC + H SE SDP
Sbjct: 257 YKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC----YGAHNLSSECSAPSDP 312
Query: 488 VELLV 492
+++L+
Sbjct: 313 LDILI 317
Score = 53.5 bits (127), Expect = 4e-07
Identities = 94/403 (23%), Positives = 152/403 (37%), Gaps = 66/403 (16%)
Query: 15 WGPVTEAAIFYET----QPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQEPV 70
W +++ + T +P+L A+ ++ VTL C++ + F L K G + P
Sbjct: 106 WSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQ 165
Query: 71 HLDSP--------AIKHQFLLTGDTQGRYRCRS---GLSTGWTQLSKLLELTGPKSLPAP 119
L+S AI ++ + + +RC W+ S LLEL P P
Sbjct: 166 CLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKP 225
Query: 120 WLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDV---EATF---P 173
LS+ P + PG T C + F+L +EG+ + ++P Q +A F P
Sbjct: 226 SLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGP 285
Query: 174 VHQP--GNYSCSYRTDGEGALSEPS--ATVTIEELAAPPPPVLMHHGESSQVLHPGNKVT 229
V + G Y C + S PS + I P + + G + + G VT
Sbjct: 286 VSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPT---VASGENVT 342
Query: 230 LTCVAPLSGVDFQLRRG---EKELLVPRSSTSPD-RIFFHLNAVALGDGGHYTCRYRLHD 285
L C + F L + + L + P + F ++ V G Y C L+
Sbjct: 343 LLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNS 402
Query: 286 NQNGWSGDSAPVELILSDETL------------PAPEFSP------EPESGRALRLRCLA 327
+ S S P+EL++S ++ P PE P +P+SG L +
Sbjct: 403 DPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPGPEDQPLTPTGSDPQSGLGRHLGVVI 462
Query: 328 PLEGA----------RFALVREDRGGR------RVHRFQSPAG 354
+ A F ++R R G+ R FQ PAG
Sbjct: 463 GILVAVVLLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAG 505
Score = 39.3 bits (90), Expect = 0.008
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAAN--L 455
G P+P L A + G L C+G + + L RE ++ + T P N
Sbjct: 24 GTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQF 83
Query: 456 ELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
+ + +H G Y C+Y S SELSDP+ L++
Sbjct: 84 HIPSITWEHTGRYGCQYYS---RARWSELSDPLVLVM 117
>gi|47519953 leukocyte immunoglobulin-like receptor subfamily A
member 4 [Homo sapiens]
Length = 499
Score = 109 bits (272), Expect = 7e-24
Identities = 111/424 (26%), Positives = 177/424 (41%), Gaps = 31/424 (7%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M++++ LL +G++ GP T +P LWAE ++ VT+ CQ LE ++L
Sbjct: 1 MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
Query: 61 FKNGVAQEPVHLDSPAIKHQFLLT-----GDTQGRYRCRSGLSTGWTQLSKLLELTGPKS 115
K G + L + +++ L+ + GRY C GW++ S LEL +
Sbjct: 61 DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELV-VTA 119
Query: 116 LPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQE----DVEAT 171
P LS P +T G+ T C L F L EGDH + + +A
Sbjct: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
Query: 172 FPV-----HQPGNYSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPG 225
FP+ G + C Y + SEPS + + P L+ V+ PG
Sbjct: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLL--TLQGPVVTPG 237
Query: 226 NKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSP----DRIFFHLNAVALGDGGHYTCRY 281
+TL C + + + + L + + L R P + F L+ V+ GG Y C Y
Sbjct: 238 ENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRC-Y 296
Query: 282 RLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEGARFALV 337
H+ + WS S P++++++ + P S +P SG + L C + F L
Sbjct: 297 GAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLT 356
Query: 338 REDRGGRRVHRFQSPAGT---EALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLEL 394
+E + R +S G +A F + ++ A + Y C P+ S PSE LEL
Sbjct: 357 KEGAAHPPL-RLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLEL 415
Query: 395 HVDG 398
V G
Sbjct: 416 VVSG 419
Score = 87.4 bits (215), Expect = 3e-17
Identities = 83/313 (26%), Positives = 137/313 (43%), Gaps = 26/313 (8%)
Query: 195 PSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELL--V 252
P V E L P P+L E V+ N VT+ C L ++L + + +
Sbjct: 17 PRTRVQAENL---PKPILW--AEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHI 71
Query: 253 PRSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFS 312
++ S +++ + ++ G Y C Y+ + GWS S P+EL+++ + P
Sbjct: 72 LKTLESENKVKLSIPSMMWEHAGRYHCYYQ---SPAGWSEPSDPLELVVTAYSRPTLSAL 128
Query: 313 PEP--ESGRALRLRCLAPLEGARFALVRED--RGGRRVHRFQSPAGT-EALFELHNISVA 367
P P SG + LRC + L RF L+ E R ++ Q G +ALF + ++ +
Sbjct: 129 PSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFS 188
Query: 368 DSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPI 427
+ + C + P+ S PS+ L+L V G +P L V G + L+C +
Sbjct: 189 NRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDV 248
Query: 428 PDVTFELLREG-ETKAVKTVRTPGAA---ANLELIFVGPQHAGNYRCRYRSWVPHTFESE 483
+ + L +EG + + R P A AN L V + G YRC + H SE
Sbjct: 249 GYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRC----YGAHNVSSE 304
Query: 484 L---SDPVELLVA 493
SDP+++L+A
Sbjct: 305 WSAPSDPLDILIA 317
Score = 86.3 bits (212), Expect = 6e-17
Identities = 110/409 (26%), Positives = 169/409 (41%), Gaps = 43/409 (10%)
Query: 114 KSLPAP--WLSMAPV-SWITPGLKTTAVCRGVLRGVTFLLRREGD---HEFLEVPEAQED 167
++LP P W PV +W P T C+G L + L +EG+ L+ E++
Sbjct: 24 ENLPKPILWAEPGPVITWHNP---VTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENK 80
Query: 168 VEATFPV---HQPGNYSCSYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHP 224
V+ + P G Y C Y++ SEPS + + A P + S V+
Sbjct: 81 VKLSIPSMMWEHAGRYHCYYQSPA--GWSEPSDPLELVVTAYSRPTL---SALPSPVVTS 135
Query: 225 GNKVTLTCVAPLSGVDFQL-RRGEKELLVPRSSTSPD----RIFFHLNAVALGDGGHYTC 279
G VTL C + L F L G+ L +S + + F + + + G + C
Sbjct: 136 GVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRC 195
Query: 280 RYRLHDNQNGWSGDSAPVELILSDE-------TLPAPEFSPEPESGRALRLRCLAPLEGA 332
++ WS S P++L++S TL P +P G L L+C + +
Sbjct: 196 YGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTP----GENLTLQCGSDVGYI 251
Query: 333 RFALVREDRGG--RRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSE 390
R+ L +E G +R R ++A F L +S + Y C Y SAPS+
Sbjct: 252 RYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRC-YGAHNVSSEWSAPSD 310
Query: 391 RLELHVDGP-PPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTP 449
L++ + G RP L V +G L C+ P TF L +EG +R+
Sbjct: 311 PLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSM 370
Query: 450 GAAANLELIF----VGPQHAGNYRC-RYRSWVPHTFESELSDPVELLVA 493
A + F V HAG YRC RS P+ S S+P+EL+V+
Sbjct: 371 YGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLL-SHPSEPLELVVS 418
Score = 42.4 bits (98), Expect = 0.001
Identities = 76/313 (24%), Positives = 119/313 (38%), Gaps = 32/313 (10%)
Query: 20 EAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQEPVHLDSPAIKH 79
E + ++P+L A ++ NVTL C + L F L + G + L+S H
Sbjct: 114 ELVVTAYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNH 173
Query: 80 ---QFL-----LTGDTQGRYRC---RSGLSTGWTQLSKLLEL--TGPKSLPAPWLSMAPV 126
Q L LT +G +RC + W++ S L+L +G P+ PV
Sbjct: 174 GKFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPV 233
Query: 127 SWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDV---EATF---PVHQP--G 178
+TPG T C + + + L +EG + P Q +A F PV + G
Sbjct: 234 --VTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGG 291
Query: 179 NYSC--SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPL 236
Y C ++ E + + I + P + + G + + G KVTL C +
Sbjct: 292 QYRCYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPT---VTSGEKVTLLCQSWD 348
Query: 237 SGVDFQLRR--GEKELLVPRSSTSPDRIF--FHLNAVALGDGGHYTCRYRLHDNQNGWSG 292
F L + L RS + F ++ V G Y C N S
Sbjct: 349 PMFTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSH 408
Query: 293 DSAPVELILSDET 305
S P+EL++S T
Sbjct: 409 PSEPLELVVSGAT 421
>gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 1 [Homo sapiens]
Length = 489
Score = 107 bits (268), Expect = 2e-23
Identities = 117/433 (27%), Positives = 186/433 (42%), Gaps = 47/433 (10%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ +V L+ ++ GP T +P+LWAE S++ + VTL CQ LET +++L
Sbjct: 1 MTPIVTVLICLRLSLGPRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRL 60
Query: 61 FK--------NGVAQEPVHLDSPAIKHQF---LLTGDTQGRYRCRSGLST-GWTQLSKLL 108
++ + QE V K QF +T + GRYRC G T GW++ S L
Sbjct: 61 YREKKTAPWITRIPQEIVK------KGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPL 114
Query: 109 ELTGPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDV 168
EL + P LS P +T G T C + +F+L +EG+ E + +Q
Sbjct: 115 ELVVTGAYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRT 174
Query: 169 ----EATFPV-----HQPGNYSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGES 218
A F V + +Y C +Y ++ S PS + + L P L +
Sbjct: 175 HGWSRAIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSL--SVQP 232
Query: 219 SQVLHPGNKVTLTCVAPLSGVDFQL-RRGEKELLV---PRSSTSPDRIFFHLNAVALGDG 274
++ PG +TL CV+ +S F L + GE++ L P+ + F L V+ G
Sbjct: 233 GPIVAPGESLTLQCVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYG 292
Query: 275 GHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLE 330
G Y C ++ + WS S P++++++ + P S P SG + L C +
Sbjct: 293 GQYRCS-GAYNLSSEWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVTLLCQSWGP 351
Query: 331 GARFALVREDRGG-----RRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGG 385
F L + R +H + +A F + ++ A S Y C P+
Sbjct: 352 FHTFLLTKAGAADAPLRLRSIHEYPK---YQAEFPMSPVTSAHSGTYRCYGSLSSNPYLL 408
Query: 386 SAPSERLELHVDG 398
S PS+ LEL V G
Sbjct: 409 SHPSDSLELMVSG 421
Score = 79.3 bits (194), Expect = 7e-15
Identities = 83/303 (27%), Positives = 125/303 (41%), Gaps = 27/303 (8%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIF---- 263
P P L E V+ G+ VTL C L +++L R +K P + P I
Sbjct: 27 PKPTLW--AEPGSVITQGSPVTLWCQGILETQEYRLYREKKT--APWITRIPQEIVKKGQ 82
Query: 264 FHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETL-PAPEFSPEP--ESGRA 320
F + ++ G Y C Y H GWS S P+EL+++ + P P P SG
Sbjct: 83 FPIPSITWEHTGRYRCFYGSHTA--GWSEPSDPLELVVTGAYIKPTLSALPSPVVTSGGN 140
Query: 321 LRLRCLAPLEGARFALVREDRGGRRVHRFQSP---AGTEALFELHNISVADSANYSCVYV 377
+ L C++ + F L +E P + A+F + +S + +Y C
Sbjct: 141 VTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYAY 200
Query: 378 DLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLRE 437
D P S PS+ LEL V G +P L V G L+C + F L +E
Sbjct: 201 DSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYKE 260
Query: 438 GETKAVKTVRTPG-------AAANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVEL 490
GE ++ PG + AN L V + G YRC ++ + S SDP+++
Sbjct: 261 GER---DFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCS-GAYNLSSEWSAPSDPLDI 316
Query: 491 LVA 493
L+A
Sbjct: 317 LIA 319
Score = 39.3 bits (90), Expect = 0.008
Identities = 33/99 (33%), Positives = 44/99 (44%), Gaps = 8/99 (8%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPG---AAAN 454
G P+P L A + G L C+G + + L RE +T A R P
Sbjct: 24 GTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKT-APWITRIPQEIVKKGQ 82
Query: 455 LELIFVGPQHAGNYRCRYRSWVPHTFE-SELSDPVELLV 492
+ + +H G YRC Y S HT SE SDP+EL+V
Sbjct: 83 FPIPSITWEHTGRYRCFYGS---HTAGWSEPSDPLELVV 118
>gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 1 [Homo sapiens]
Length = 591
Score = 106 bits (264), Expect = 6e-23
Identities = 121/443 (27%), Positives = 182/443 (41%), Gaps = 33/443 (7%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M++ + L+ G++ GP T +P+LWAE S++ VTL CQ LET +++L
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 FKNGV-----AQEPVHLDSPAIKHQFLLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKS 115
K G+ Q P+ + A H D+ GRYRC GW++ S LEL
Sbjct: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGF 120
Query: 116 LPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQE----DVEAT 171
P L P + G T C + +TF+L E + + +Q+ +A
Sbjct: 121 YAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEE-EQKLPRTLYSQKLPKGPSQAL 179
Query: 172 FPVHQPGNYSCSYR-------TDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHP 224
FPV P SC +R S PS + I P L+ V+
Sbjct: 180 FPV-GPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLI--PQGSVVAR 236
Query: 225 GNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSP----DRIFFHLNAVALGDGGHYTCR 280
G +TL C + + F L + + LV S P + F L V+ GG Y C
Sbjct: 237 GGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC- 295
Query: 281 YRLHDNQNGWSGDSAPVELILSD--ETLPAPEFSPEPE--SGRALRLRCLAPLEGARFAL 336
Y H+ WS S P++++++ +PA P P+ SG + L C + + F L
Sbjct: 296 YGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFL 355
Query: 337 VREDRGGRRV---HRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLE 393
+E + ++QS +A F + ++ A Y C P+ S+PS E
Sbjct: 356 TKEGAAHPPLCLKSKYQS-YRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQE 414
Query: 394 LHVDGPPPRPQLRATWSGAVLAG 416
L V GP P L T S AG
Sbjct: 415 LVVSGPSGDPSLSPTGSTPTPAG 437
Score = 86.3 bits (212), Expect = 6e-17
Identities = 91/301 (30%), Positives = 136/301 (45%), Gaps = 25/301 (8%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSP----DRIF 263
P P L E + V+ G VTL C PL +++L + + L R +P +
Sbjct: 27 PKPTLW--AEPASVIARGKPVTLWCQGPLETEEYRLDK--EGLPWARKRQNPLEPGAKAK 82
Query: 264 FHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILS----DETLPAPEFSPEPESGR 319
FH+ + G Y C Y + GWS S P+EL+ + + TL A SP SG
Sbjct: 83 FHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGFYAEPTLLALP-SPVVASGG 138
Query: 320 ALRLRCLAPLEGA-RFALVREDRG-GRRVHRFQSPAG-TEALFELHNISVADSANYSCVY 376
+ L+C L+G F LV E++ R ++ + P G ++ALF + ++ + + C Y
Sbjct: 139 NVTLQC-DTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYY 197
Query: 377 VDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLR 436
K P S PS+ LE+ V G +P L V G L+C + F L +
Sbjct: 198 YYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYK 257
Query: 437 EGETKAVK-TVRTPGAA---ANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
EGE V+ + + P A AN L V H G YRC Y + S SDP+++L+
Sbjct: 258 EGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLSPRWSAPSDPLDILI 316
Query: 493 A 493
A
Sbjct: 317 A 317
Score = 45.8 bits (107), Expect = 9e-05
Identities = 33/99 (33%), Positives = 45/99 (45%), Gaps = 11/99 (11%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVR--TPGAAANL 455
G P+P L A + + G+ L C+GP+ + L +EG A K PGA A
Sbjct: 24 GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83
Query: 456 ELIFVGPQHAGNYRCRYRS---WVPHTFESELSDPVELL 491
+ AG YRC Y + W SE SDP+EL+
Sbjct: 84 HIPSTVYDSAGRYRCYYETPAGW------SEPSDPLELV 116
>gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 2 [Homo sapiens]
Length = 590
Score = 105 bits (261), Expect = 1e-22
Identities = 123/455 (27%), Positives = 184/455 (40%), Gaps = 33/455 (7%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M++ + L+ G++ GP T +P+LWAE S++ VTL CQ LET +++L
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 FKNGV-----AQEPVHLDSPAIKHQFLLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKS 115
K G+ Q P+ + A H D+ GRYRC GW++ S LEL
Sbjct: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGF 120
Query: 116 LPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQE----DVEAT 171
P L P + G T C + +TF+L E + + +Q+ +A
Sbjct: 121 YAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEE-EQKLPRTLYSQKLPKGPSQAL 179
Query: 172 FPVHQPGNYSCSYR-------TDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHP 224
FPV P SC +R S PS + I P L+ V+
Sbjct: 180 FPV-GPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLI--PQGSVVAR 236
Query: 225 GNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSP----DRIFFHLNAVALGDGGHYTCR 280
G +TL C + + F L + + LV S P + F L V+ GG Y C
Sbjct: 237 GGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC- 295
Query: 281 YRLHDNQNGWSGDSAPVELILSD--ETLPAPEFSPEPE--SGRALRLRCLAPLEGARFAL 336
Y H+ WS S P++++++ +PA P P+ SG + L C + + F L
Sbjct: 296 YGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFL 355
Query: 337 VREDRGGRRV---HRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLE 393
+E + ++QS +A F + ++ A Y C P+ S+PS E
Sbjct: 356 TKEGAAHPPLCLKSKYQS-YRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQE 414
Query: 394 LHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIP 428
L V GP P L T S D L G P
Sbjct: 415 LVVSGPSGDPSLSPTGSTPTPGPEDQPLTPTGLDP 449
Score = 86.3 bits (212), Expect = 6e-17
Identities = 91/301 (30%), Positives = 136/301 (45%), Gaps = 25/301 (8%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSP----DRIF 263
P P L E + V+ G VTL C PL +++L + + L R +P +
Sbjct: 27 PKPTLW--AEPASVIARGKPVTLWCQGPLETEEYRLDK--EGLPWARKRQNPLEPGAKAK 82
Query: 264 FHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILS----DETLPAPEFSPEPESGR 319
FH+ + G Y C Y + GWS S P+EL+ + + TL A SP SG
Sbjct: 83 FHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGFYAEPTLLALP-SPVVASGG 138
Query: 320 ALRLRCLAPLEGA-RFALVREDRG-GRRVHRFQSPAG-TEALFELHNISVADSANYSCVY 376
+ L+C L+G F LV E++ R ++ + P G ++ALF + ++ + + C Y
Sbjct: 139 NVTLQC-DTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYY 197
Query: 377 VDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLR 436
K P S PS+ LE+ V G +P L V G L+C + F L +
Sbjct: 198 YYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYK 257
Query: 437 EGETKAVK-TVRTPGAA---ANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
EGE V+ + + P A AN L V H G YRC Y + S SDP+++L+
Sbjct: 258 EGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLSPRWSAPSDPLDILI 316
Query: 493 A 493
A
Sbjct: 317 A 317
Score = 45.8 bits (107), Expect = 9e-05
Identities = 33/99 (33%), Positives = 45/99 (45%), Gaps = 11/99 (11%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVR--TPGAAANL 455
G P+P L A + + G+ L C+GP+ + L +EG A K PGA A
Sbjct: 24 GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83
Query: 456 ELIFVGPQHAGNYRCRYRS---WVPHTFESELSDPVELL 491
+ AG YRC Y + W SE SDP+EL+
Sbjct: 84 HIPSTVYDSAGRYRCYYETPAGW------SEPSDPLELV 116
>gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 2 isoform a [Homo sapiens]
Length = 483
Score = 103 bits (256), Expect = 5e-22
Identities = 109/421 (25%), Positives = 181/421 (42%), Gaps = 29/421 (6%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ ++ L+ G++ GP T + +P+LWAE S++ + VTL CQ L+ ++ L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 60
Query: 61 FK-NGVAQEPVHLDSPAIKHQF---LLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSL 116
++ N A + P QF +T + GRY C+ ++ S LEL +
Sbjct: 61 YRENKSASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAY 120
Query: 117 PAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVE----ATF 172
P LS P +T G T C + F+L +EG+ E + + A F
Sbjct: 121 SKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIF 180
Query: 173 PV-----HQPGNYSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGN 226
V + +Y C +Y ++ S PS + + P L + ++ PG
Sbjct: 181 SVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSL--SVQPGPMVAPGE 238
Query: 227 KVTLTCVAPLSGVDFQL-RRGEKELLVPRSSTSP----DRIFFHLNAVALGDGGHYTCRY 281
+TL CV+ + F L + GE++ L R P + F L V+ GG Y C Y
Sbjct: 239 SLTLQCVSDVGYDRFVLYKEGERDFL-QRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-Y 296
Query: 282 RLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEGARFALV 337
H+ + WS S P++++++ + P S +P G+ + L C + + F L
Sbjct: 297 SAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLT 356
Query: 338 REDRGGRRVH-RFQSPA-GTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELH 395
+E G +H R + A +A F + ++ A Y C P+ S PS+ LEL
Sbjct: 357 KEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELV 416
Query: 396 V 396
V
Sbjct: 417 V 417
Score = 89.0 bits (219), Expect = 9e-18
Identities = 86/303 (28%), Positives = 130/303 (42%), Gaps = 31/303 (10%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIF-FHL 266
P P L E V+ G+ VTL C L ++ L R K R P + F +
Sbjct: 27 PKPTLW--AEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFPI 84
Query: 267 NAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELIL----SDETLPAPEFSPEPESGRALR 322
++ G Y C+Y H++ + +S P+EL++ S TL A SP G +
Sbjct: 85 PSITWEHAGRYHCQYYSHNHSSEYSD---PLELVVTGAYSKPTLSALP-SPVVTLGGNVT 140
Query: 323 LRCLAPLEGARFALVRE--DRGGRRVHRFQSPAGTE-ALFELHNISVADSANYSCVYVDL 379
L+C++ + F L +E D +R++ G A+F + +S + +Y C D
Sbjct: 141 LQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDS 200
Query: 380 KPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGE 439
P+ S PS+ LEL V G +P L V G L+C + F L +EGE
Sbjct: 201 NSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGE 260
Query: 440 TKAVKTVRTPG-------AAANLELIFVGPQHAGNYRCRYRSWVPHTFESEL---SDPVE 489
++ PG + AN L V P H G YRC + H SE SDP++
Sbjct: 261 R---DFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC----YSAHNLSSEWSAPSDPLD 313
Query: 490 LLV 492
+L+
Sbjct: 314 ILI 316
Score = 80.5 bits (197), Expect = 3e-15
Identities = 111/402 (27%), Positives = 166/402 (41%), Gaps = 29/402 (7%)
Query: 116 LPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPV- 174
LP P L P S I G T C+G L+ + L RE + FP+
Sbjct: 26 LPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFPIP 85
Query: 175 ----HQPGNYSCSYRTDGEGA-LSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVT 229
G Y C Y + + S+P V + P L S V+ G VT
Sbjct: 86 SITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAYSKPTLSAL-----PSPVVTLGGNVT 140
Query: 230 LTCVAPLSGVDFQL-RRGEKELLVPRSSTSPDR----IFFHLNAVALGDGGHYTCRYRLH 284
L CV+ ++ F L + GE E +S S R F + V+ Y C
Sbjct: 141 LQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDS 200
Query: 285 DNQNGWSGDSAPVELILSDETL-PAPEFSPEP--ESGRALRLRCLAPLEGARFALVRE-D 340
++ WS S +EL++ + P+ P P G +L L+C++ + RF L +E +
Sbjct: 201 NSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGE 260
Query: 341 RGGRRVHRFQSPAG-TEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGP 399
R + +Q AG ++A F L +S + Y C Y SAPS+ L++ + G
Sbjct: 261 RDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLSSEWSAPSDPLDILITGQ 319
Query: 400 -PPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELI 458
RP L V G++ L C+ TF L +EG +R+ A +
Sbjct: 320 FYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAE 379
Query: 459 F-VGP---QHAGNYRCRYRSWVPHTFESEL-SDPVELLVAES 495
F +GP H G YRC Y S + + L SDP+EL+V+E+
Sbjct: 380 FRMGPVTSAHVGTYRC-YSSLSSNPYLLSLPSDPLELVVSEA 420
Score = 61.2 bits (147), Expect = 2e-09
Identities = 85/315 (26%), Positives = 121/315 (38%), Gaps = 46/315 (14%)
Query: 27 TQPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQEPVHLDSP--------AIK 78
++P+L A ++ NVTL C + + F L K G + P L+S AI
Sbjct: 121 SKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIF 180
Query: 79 HQFLLTGDTQGRYRCRSGLSTG---WTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKT 135
++ + YRC + S W+ S LLEL P P LS+ P + PG
Sbjct: 181 SVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESL 240
Query: 136 TAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDV---EATF------PVHQPGNYSCSYRT 186
T C + F+L +EG+ +FL+ P Q +A F P H G Y C
Sbjct: 241 TLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHG-GQYRCYSAH 299
Query: 187 DGEGALSEPSATVTI---------EELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLS 237
+ S PS + I L+ P P + PG VTL C +
Sbjct: 300 NLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVA----------PGKNVTLLCQSRGQ 349
Query: 238 GVDFQLRR---GEKEL-LVPRSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQNGWSGD 293
F L + G L L ++ F + V G Y C L N S
Sbjct: 350 FHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLP 409
Query: 294 SAPVELILSD--ETL 306
S P+EL++S+ ETL
Sbjct: 410 SDPLELVVSEAAETL 424
Score = 58.9 bits (141), Expect = 1e-08
Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKA-VKTVRTPGAAANLE 456
G P+P L A ++ G LRC+G + + L RE ++ + V+ ++ PG
Sbjct: 24 GHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFP 83
Query: 457 LIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
+ + +HAG Y C+Y S H SE SDP+EL+V
Sbjct: 84 IPSITWEHAGRYHCQYYS---HNHSSEYSDPLELVV 116
>gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 2 isoform b [Homo sapiens]
Length = 466
Score = 103 bits (256), Expect = 5e-22
Identities = 109/421 (25%), Positives = 181/421 (42%), Gaps = 29/421 (6%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ ++ L+ G++ GP T + +P+LWAE S++ + VTL CQ L+ ++ L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 60
Query: 61 FK-NGVAQEPVHLDSPAIKHQF---LLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSL 116
++ N A + P QF +T + GRY C+ ++ S LEL +
Sbjct: 61 YRENKSASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAY 120
Query: 117 PAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVE----ATF 172
P LS P +T G T C + F+L +EG+ E + + A F
Sbjct: 121 SKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIF 180
Query: 173 PV-----HQPGNYSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGN 226
V + +Y C +Y ++ S PS + + P L + ++ PG
Sbjct: 181 SVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSL--SVQPGPMVAPGE 238
Query: 227 KVTLTCVAPLSGVDFQL-RRGEKELLVPRSSTSP----DRIFFHLNAVALGDGGHYTCRY 281
+TL CV+ + F L + GE++ L R P + F L V+ GG Y C Y
Sbjct: 239 SLTLQCVSDVGYDRFVLYKEGERDFL-QRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-Y 296
Query: 282 RLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEGARFALV 337
H+ + WS S P++++++ + P S +P G+ + L C + + F L
Sbjct: 297 SAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLT 356
Query: 338 REDRGGRRVH-RFQSPA-GTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELH 395
+E G +H R + A +A F + ++ A Y C P+ S PS+ LEL
Sbjct: 357 KEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELV 416
Query: 396 V 396
V
Sbjct: 417 V 417
Score = 89.0 bits (219), Expect = 9e-18
Identities = 86/303 (28%), Positives = 130/303 (42%), Gaps = 31/303 (10%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIF-FHL 266
P P L E V+ G+ VTL C L ++ L R K R P + F +
Sbjct: 27 PKPTLW--AEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFPI 84
Query: 267 NAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELIL----SDETLPAPEFSPEPESGRALR 322
++ G Y C+Y H++ + +S P+EL++ S TL A SP G +
Sbjct: 85 PSITWEHAGRYHCQYYSHNHSSEYSD---PLELVVTGAYSKPTLSALP-SPVVTLGGNVT 140
Query: 323 LRCLAPLEGARFALVRE--DRGGRRVHRFQSPAGTE-ALFELHNISVADSANYSCVYVDL 379
L+C++ + F L +E D +R++ G A+F + +S + +Y C D
Sbjct: 141 LQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDS 200
Query: 380 KPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGE 439
P+ S PS+ LEL V G +P L V G L+C + F L +EGE
Sbjct: 201 NSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGE 260
Query: 440 TKAVKTVRTPG-------AAANLELIFVGPQHAGNYRCRYRSWVPHTFESEL---SDPVE 489
++ PG + AN L V P H G YRC + H SE SDP++
Sbjct: 261 R---DFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC----YSAHNLSSEWSAPSDPLD 313
Query: 490 LLV 492
+L+
Sbjct: 314 ILI 316
Score = 79.3 bits (194), Expect = 7e-15
Identities = 111/402 (27%), Positives = 165/402 (41%), Gaps = 29/402 (7%)
Query: 116 LPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPV- 174
LP P L P S I G T C+G L+ + L RE + FP+
Sbjct: 26 LPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFPIP 85
Query: 175 ----HQPGNYSCSYRTDGEGA-LSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVT 229
G Y C Y + + S+P V + P L S V+ G VT
Sbjct: 86 SITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAYSKPTLSAL-----PSPVVTLGGNVT 140
Query: 230 LTCVAPLSGVDFQL-RRGEKELLVPRSSTSPDR----IFFHLNAVALGDGGHYTCRYRLH 284
L CV+ ++ F L + GE E +S S R F + V+ Y C
Sbjct: 141 LQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDS 200
Query: 285 DNQNGWSGDSAPVELILSDETL-PAPEFSPEP--ESGRALRLRCLAPLEGARFALVRE-D 340
++ WS S +EL++ + P+ P P G +L L+C++ + RF L +E +
Sbjct: 201 NSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGE 260
Query: 341 RGGRRVHRFQSPAG-TEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGP 399
R + +Q AG ++A F L +S + Y C Y SAPS+ L++ + G
Sbjct: 261 RDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLSSEWSAPSDPLDILITGQ 319
Query: 400 -PPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELI 458
RP L V G++ L C+ TF L +EG +R+ A +
Sbjct: 320 FYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAE 379
Query: 459 F-VGP---QHAGNYRCRYRSWVPHTFESEL-SDPVELLVAES 495
F +GP H G YRC Y S + + L SDP+EL+V+ S
Sbjct: 380 FRMGPVTSAHVGTYRC-YSSLSSNPYLLSLPSDPLELVVSAS 420
Score = 60.1 bits (144), Expect = 5e-09
Identities = 82/309 (26%), Positives = 117/309 (37%), Gaps = 44/309 (14%)
Query: 27 TQPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQEPVHLDSP--------AIK 78
++P+L A ++ NVTL C + + F L K G + P L+S AI
Sbjct: 121 SKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIF 180
Query: 79 HQFLLTGDTQGRYRCRSGLSTG---WTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKT 135
++ + YRC + S W+ S LLEL P P LS+ P + PG
Sbjct: 181 SVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESL 240
Query: 136 TAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDV---EATF------PVHQPGNYSCSYRT 186
T C + F+L +EG+ +FL+ P Q +A F P H G Y C
Sbjct: 241 TLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHG-GQYRCYSAH 299
Query: 187 DGEGALSEPSATVTI---------EELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLS 237
+ S PS + I L+ P P + PG VTL C +
Sbjct: 300 NLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVA----------PGKNVTLLCQSRGQ 349
Query: 238 GVDFQLRR---GEKEL-LVPRSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQNGWSGD 293
F L + G L L ++ F + V G Y C L N S
Sbjct: 350 FHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLP 409
Query: 294 SAPVELILS 302
S P+EL++S
Sbjct: 410 SDPLELVVS 418
Score = 58.9 bits (141), Expect = 1e-08
Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKA-VKTVRTPGAAANLE 456
G P+P L A ++ G LRC+G + + L RE ++ + V+ ++ PG
Sbjct: 24 GHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFP 83
Query: 457 LIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
+ + +HAG Y C+Y S H SE SDP+EL+V
Sbjct: 84 IPSITWEHAGRYHCQYYS---HNHSSEYSDPLELVV 116
>gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 3 [Homo sapiens]
Length = 651
Score = 99.8 bits (247), Expect = 5e-21
Identities = 119/448 (26%), Positives = 189/448 (42%), Gaps = 41/448 (9%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ ++ L+ G++ GP T + +P+LWAE S++ + VTL CQ ET +++L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 FKN-----GVAQEPVHLDSPAIKHQF---LLTGDTQGRYRCRSGLST-GWTQLSKLLELT 111
++ + + P L K QF +T + GRYRC G T G ++ S LEL
Sbjct: 61 YREKKTALWITRIPQEL---VKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELV 117
Query: 112 GPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEV----PEAQED 167
+ P LS P + G C + F L +EG+ E + P A+
Sbjct: 118 VTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGS 177
Query: 168 VEATFPVH--QPGN---YSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQV 221
A F V P Y C +Y ++ S PS + + L P L + +
Sbjct: 178 SRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSL--SVQPGPI 235
Query: 222 LHPGNKVTLTCVAPLSGVDFQL-RRGEKELL-----VPRSSTSPDRIFFHLNAVALGDGG 275
+ P +TL C + F L + GE++ L P++ S + F L V+ GG
Sbjct: 236 VAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLS--QANFTLGPVSRSYGG 293
Query: 276 HYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEG 331
Y C Y H+ + WS S P++++++ + S +P SG + L C +
Sbjct: 294 QYRC-YGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWM 352
Query: 332 ARFALVRE---DRGGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAP 388
F L +E D R +QS +A F + ++ A + Y C P+ + P
Sbjct: 353 QTFLLTKEGAADDPWRLRSTYQSQK-YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHP 411
Query: 389 SERLELHVDGPPPRPQLRATWSGAVLAG 416
S+ LEL V GP P T + AG
Sbjct: 412 SDPLELVVSGPSGGPSSPTTGPTSTSAG 439
Score = 68.9 bits (167), Expect = 1e-11
Identities = 78/303 (25%), Positives = 121/303 (39%), Gaps = 27/303 (8%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELL----VPRSSTSPDRIF 263
P P L E V+ G+ VTL C +++L R +K L +P+ +
Sbjct: 27 PKPTLW--AEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQ-- 82
Query: 264 FHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETL-PAPEFSPEP--ESGRA 320
F + ++ G Y C Y + G S S P+EL+++ + P P P SG
Sbjct: 83 FPIPSITWEHAGRYRCYYG--SDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140
Query: 321 LRLRCLAPLEGARFALVREDRGGRRVHRFQSP---AGTEALFELHNISVADSANYSCVYV 377
+ L+C + + F+L +E P + A+F + +S + Y C
Sbjct: 141 VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200
Query: 378 DLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLRE 437
D P+ S PS+ LEL V G +P L V L+C F L ++
Sbjct: 201 DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260
Query: 438 GETKAVKTVRTPGAA----ANLELIFVGPQHAGNYRCRYRSWVPHTFESEL---SDPVEL 490
GE ++ A AN L V + G YRC + H SE SDP+++
Sbjct: 261 GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC----YGAHNLSSEWSAPSDPLDI 316
Query: 491 LVA 493
L+A
Sbjct: 317 LIA 319
Score = 60.8 bits (146), Expect = 3e-09
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 13/197 (6%)
Query: 306 LPAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFEL 361
LP P EP S G + LRC E + L RE + + R + F +
Sbjct: 26 LPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQFPI 85
Query: 362 HNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVL 421
+I+ + Y C Y G S S+ LEL V G +P L A S V +G + +L
Sbjct: 86 PSITWEHAGRYRCYYGS--DTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143
Query: 422 RCEGPIPDVTFELLREGETKAVKTVRT-PGAAANLELIF----VGPQHAGNYRC-RYRSW 475
+C+ + F L +EGE + + + + P A + IF V P YRC Y S
Sbjct: 144 QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203
Query: 476 VPHTFESELSDPVELLV 492
P+ + S SD +ELLV
Sbjct: 204 SPYEW-SLPSDLLELLV 219
Score = 43.1 bits (100), Expect = 6e-04
Identities = 33/98 (33%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPG---AAAN 454
G P+P L A + G LRC+G + L RE +T A+ R P
Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKT-ALWITRIPQELVKKGQ 82
Query: 455 LELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
+ + +HAG YRC Y S SE SDP+EL+V
Sbjct: 83 FPIPSITWEHAGRYRCYYGS--DTAGRSESSDPLELVV 118
>gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 2 [Homo sapiens]
Length = 652
Score = 99.8 bits (247), Expect = 5e-21
Identities = 119/448 (26%), Positives = 189/448 (42%), Gaps = 41/448 (9%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ ++ L+ G++ GP T + +P+LWAE S++ + VTL CQ ET +++L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 FKN-----GVAQEPVHLDSPAIKHQF---LLTGDTQGRYRCRSGLST-GWTQLSKLLELT 111
++ + + P L K QF +T + GRYRC G T G ++ S LEL
Sbjct: 61 YREKKTALWITRIPQEL---VKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELV 117
Query: 112 GPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEV----PEAQED 167
+ P LS P + G C + F L +EG+ E + P A+
Sbjct: 118 VTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGS 177
Query: 168 VEATFPVH--QPGN---YSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQV 221
A F V P Y C +Y ++ S PS + + L P L + +
Sbjct: 178 SRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSL--SVQPGPI 235
Query: 222 LHPGNKVTLTCVAPLSGVDFQL-RRGEKELL-----VPRSSTSPDRIFFHLNAVALGDGG 275
+ P +TL C + F L + GE++ L P++ S + F L V+ GG
Sbjct: 236 VAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLS--QANFTLGPVSRSYGG 293
Query: 276 HYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEG 331
Y C Y H+ + WS S P++++++ + S +P SG + L C +
Sbjct: 294 QYRC-YGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWM 352
Query: 332 ARFALVRE---DRGGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAP 388
F L +E D R +QS +A F + ++ A + Y C P+ + P
Sbjct: 353 QTFLLTKEGAADDPWRLRSTYQSQK-YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHP 411
Query: 389 SERLELHVDGPPPRPQLRATWSGAVLAG 416
S+ LEL V GP P T + AG
Sbjct: 412 SDPLELVVSGPSGGPSSPTTGPTSTSAG 439
Score = 68.9 bits (167), Expect = 1e-11
Identities = 78/303 (25%), Positives = 121/303 (39%), Gaps = 27/303 (8%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELL----VPRSSTSPDRIF 263
P P L E V+ G+ VTL C +++L R +K L +P+ +
Sbjct: 27 PKPTLW--AEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQ-- 82
Query: 264 FHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETL-PAPEFSPEP--ESGRA 320
F + ++ G Y C Y + G S S P+EL+++ + P P P SG
Sbjct: 83 FPIPSITWEHAGRYRCYYG--SDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140
Query: 321 LRLRCLAPLEGARFALVREDRGGRRVHRFQSP---AGTEALFELHNISVADSANYSCVYV 377
+ L+C + + F+L +E P + A+F + +S + Y C
Sbjct: 141 VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200
Query: 378 DLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLRE 437
D P+ S PS+ LEL V G +P L V L+C F L ++
Sbjct: 201 DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260
Query: 438 GETKAVKTVRTPGAA----ANLELIFVGPQHAGNYRCRYRSWVPHTFESEL---SDPVEL 490
GE ++ A AN L V + G YRC + H SE SDP+++
Sbjct: 261 GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC----YGAHNLSSEWSAPSDPLDI 316
Query: 491 LVA 493
L+A
Sbjct: 317 LIA 319
Score = 60.8 bits (146), Expect = 3e-09
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 13/197 (6%)
Query: 306 LPAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFEL 361
LP P EP S G + LRC E + L RE + + R + F +
Sbjct: 26 LPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQFPI 85
Query: 362 HNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVL 421
+I+ + Y C Y G S S+ LEL V G +P L A S V +G + +L
Sbjct: 86 PSITWEHAGRYRCYYGS--DTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143
Query: 422 RCEGPIPDVTFELLREGETKAVKTVRT-PGAAANLELIF----VGPQHAGNYRC-RYRSW 475
+C+ + F L +EGE + + + + P A + IF V P YRC Y S
Sbjct: 144 QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203
Query: 476 VPHTFESELSDPVELLV 492
P+ + S SD +ELLV
Sbjct: 204 SPYEW-SLPSDLLELLV 219
Score = 43.1 bits (100), Expect = 6e-04
Identities = 33/98 (33%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPG---AAAN 454
G P+P L A + G LRC+G + L RE +T A+ R P
Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKT-ALWITRIPQELVKKGQ 82
Query: 455 LELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
+ + +HAG YRC Y S SE SDP+EL+V
Sbjct: 83 FPIPSITWEHAGRYRCYYGS--DTAGRSESSDPLELVV 118
>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 4 [Homo sapiens]
Length = 651
Score = 99.4 bits (246), Expect = 7e-21
Identities = 121/460 (26%), Positives = 191/460 (41%), Gaps = 41/460 (8%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ ++ L+ G++ GP T + +P+LWAE S++ + VTL CQ ET +++L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 FKN-----GVAQEPVHLDSPAIKHQF---LLTGDTQGRYRCRSGLST-GWTQLSKLLELT 111
++ + + P L K QF +T + GRYRC G T G ++ S LEL
Sbjct: 61 YREKKTALWITRIPQEL---VKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELV 117
Query: 112 GPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEV----PEAQED 167
+ P LS P + G C + F L +EG+ E + P A+
Sbjct: 118 VTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGS 177
Query: 168 VEATFPVH--QPGN---YSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQV 221
A F V P Y C +Y ++ S PS + + L P L + +
Sbjct: 178 SRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSL--SVQPGPI 235
Query: 222 LHPGNKVTLTCVAPLSGVDFQL-RRGEKELL-----VPRSSTSPDRIFFHLNAVALGDGG 275
+ P +TL C + F L + GE++ L P++ S + F L V+ GG
Sbjct: 236 VAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLS--QANFTLGPVSRSYGG 293
Query: 276 HYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEG 331
Y C Y H+ + WS S P++++++ + S +P SG + L C +
Sbjct: 294 QYRC-YGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWM 352
Query: 332 ARFALVRE---DRGGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAP 388
F L +E D R +QS +A F + ++ A + Y C P+ + P
Sbjct: 353 QTFLLTKEGAADDPWRLRSTYQSQK-YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHP 411
Query: 389 SERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIP 428
S+ LEL V GP P T + D L G P
Sbjct: 412 SDPLELVVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDP 451
Score = 68.9 bits (167), Expect = 1e-11
Identities = 78/303 (25%), Positives = 121/303 (39%), Gaps = 27/303 (8%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELL----VPRSSTSPDRIF 263
P P L E V+ G+ VTL C +++L R +K L +P+ +
Sbjct: 27 PKPTLW--AEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQ-- 82
Query: 264 FHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETL-PAPEFSPEP--ESGRA 320
F + ++ G Y C Y + G S S P+EL+++ + P P P SG
Sbjct: 83 FPIPSITWEHAGRYRCYYG--SDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140
Query: 321 LRLRCLAPLEGARFALVREDRGGRRVHRFQSP---AGTEALFELHNISVADSANYSCVYV 377
+ L+C + + F+L +E P + A+F + +S + Y C
Sbjct: 141 VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200
Query: 378 DLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLRE 437
D P+ S PS+ LEL V G +P L V L+C F L ++
Sbjct: 201 DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260
Query: 438 GETKAVKTVRTPGAA----ANLELIFVGPQHAGNYRCRYRSWVPHTFESEL---SDPVEL 490
GE ++ A AN L V + G YRC + H SE SDP+++
Sbjct: 261 GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC----YGAHNLSSEWSAPSDPLDI 316
Query: 491 LVA 493
L+A
Sbjct: 317 LIA 319
Score = 60.8 bits (146), Expect = 3e-09
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 13/197 (6%)
Query: 306 LPAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFEL 361
LP P EP S G + LRC E + L RE + + R + F +
Sbjct: 26 LPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQFPI 85
Query: 362 HNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVL 421
+I+ + Y C Y G S S+ LEL V G +P L A S V +G + +L
Sbjct: 86 PSITWEHAGRYRCYYGS--DTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143
Query: 422 RCEGPIPDVTFELLREGETKAVKTVRT-PGAAANLELIF----VGPQHAGNYRC-RYRSW 475
+C+ + F L +EGE + + + + P A + IF V P YRC Y S
Sbjct: 144 QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203
Query: 476 VPHTFESELSDPVELLV 492
P+ + S SD +ELLV
Sbjct: 204 SPYEW-SLPSDLLELLV 219
Score = 43.1 bits (100), Expect = 6e-04
Identities = 33/98 (33%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPG---AAAN 454
G P+P L A + G LRC+G + L RE +T A+ R P
Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKT-ALWITRIPQELVKKGQ 82
Query: 455 LELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
+ + +HAG YRC Y S SE SDP+EL+V
Sbjct: 83 FPIPSITWEHAGRYRCYYGS--DTAGRSESSDPLELVV 118
>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 1 [Homo sapiens]
Length = 650
Score = 99.4 bits (246), Expect = 7e-21
Identities = 121/460 (26%), Positives = 191/460 (41%), Gaps = 41/460 (8%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ ++ L+ G++ GP T + +P+LWAE S++ + VTL CQ ET +++L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 FKN-----GVAQEPVHLDSPAIKHQF---LLTGDTQGRYRCRSGLST-GWTQLSKLLELT 111
++ + + P L K QF +T + GRYRC G T G ++ S LEL
Sbjct: 61 YREKKTALWITRIPQEL---VKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELV 117
Query: 112 GPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEV----PEAQED 167
+ P LS P + G C + F L +EG+ E + P A+
Sbjct: 118 VTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGS 177
Query: 168 VEATFPVH--QPGN---YSC-SYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQV 221
A F V P Y C +Y ++ S PS + + L P L + +
Sbjct: 178 SRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSL--SVQPGPI 235
Query: 222 LHPGNKVTLTCVAPLSGVDFQL-RRGEKELL-----VPRSSTSPDRIFFHLNAVALGDGG 275
+ P +TL C + F L + GE++ L P++ S + F L V+ GG
Sbjct: 236 VAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLS--QANFTLGPVSRSYGG 293
Query: 276 HYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEG 331
Y C Y H+ + WS S P++++++ + S +P SG + L C +
Sbjct: 294 QYRC-YGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWM 352
Query: 332 ARFALVRE---DRGGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAP 388
F L +E D R +QS +A F + ++ A + Y C P+ + P
Sbjct: 353 QTFLLTKEGAADDPWRLRSTYQSQK-YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHP 411
Query: 389 SERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIP 428
S+ LEL V GP P T + D L G P
Sbjct: 412 SDPLELVVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDP 451
Score = 68.9 bits (167), Expect = 1e-11
Identities = 78/303 (25%), Positives = 121/303 (39%), Gaps = 27/303 (8%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELL----VPRSSTSPDRIF 263
P P L E V+ G+ VTL C +++L R +K L +P+ +
Sbjct: 27 PKPTLW--AEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQ-- 82
Query: 264 FHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETL-PAPEFSPEP--ESGRA 320
F + ++ G Y C Y + G S S P+EL+++ + P P P SG
Sbjct: 83 FPIPSITWEHAGRYRCYYG--SDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140
Query: 321 LRLRCLAPLEGARFALVREDRGGRRVHRFQSP---AGTEALFELHNISVADSANYSCVYV 377
+ L+C + + F+L +E P + A+F + +S + Y C
Sbjct: 141 VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200
Query: 378 DLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLRE 437
D P+ S PS+ LEL V G +P L V L+C F L ++
Sbjct: 201 DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260
Query: 438 GETKAVKTVRTPGAA----ANLELIFVGPQHAGNYRCRYRSWVPHTFESEL---SDPVEL 490
GE ++ A AN L V + G YRC + H SE SDP+++
Sbjct: 261 GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC----YGAHNLSSEWSAPSDPLDI 316
Query: 491 LVA 493
L+A
Sbjct: 317 LIA 319
Score = 60.8 bits (146), Expect = 3e-09
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 13/197 (6%)
Query: 306 LPAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFEL 361
LP P EP S G + LRC E + L RE + + R + F +
Sbjct: 26 LPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQFPI 85
Query: 362 HNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVL 421
+I+ + Y C Y G S S+ LEL V G +P L A S V +G + +L
Sbjct: 86 PSITWEHAGRYRCYYGS--DTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143
Query: 422 RCEGPIPDVTFELLREGETKAVKTVRT-PGAAANLELIF----VGPQHAGNYRC-RYRSW 475
+C+ + F L +EGE + + + + P A + IF V P YRC Y S
Sbjct: 144 QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203
Query: 476 VPHTFESELSDPVELLV 492
P+ + S SD +ELLV
Sbjct: 204 SPYEW-SLPSDLLELLV 219
Score = 43.1 bits (100), Expect = 6e-04
Identities = 33/98 (33%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPG---AAAN 454
G P+P L A + G LRC+G + L RE +T A+ R P
Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKT-ALWITRIPQELVKKGQ 82
Query: 455 LELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
+ + +HAG YRC Y S SE SDP+EL+V
Sbjct: 83 FPIPSITWEHAGRYRCYYGS--DTAGRSESSDPLELVV 118
>gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A
(without TM domain), member 3 [Homo sapiens]
Length = 439
Score = 91.3 bits (225), Expect = 2e-18
Identities = 108/428 (25%), Positives = 174/428 (40%), Gaps = 37/428 (8%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M+ ++ L+ G++ P T +P+LWAE S++ + VTL CQ LET ++ L
Sbjct: 1 MTSILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHL 60
Query: 61 FKN-----GVAQEPVHLDSPAIKHQFLLTGDTQGRYRCRSGLST-GWTQLSKLLELTGPK 114
++ + + P L +T + GRY C G T G ++ S LEL
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTVGLSESSDPLELVVTG 120
Query: 115 SLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEV----PEAQEDVEA 170
+ P LS P +T G T C + F+L +EG+ E + A+ A
Sbjct: 121 AYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRA 180
Query: 171 TFPVHQPG-NYSCSYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQ---VLHPGN 226
F V + SYR G + + ++ + L P V S Q V+ PG
Sbjct: 181 IFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGE 240
Query: 227 KVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSP----DRIFFHLNAVALGDGGHYTCRYR 282
K+T C + F L + + R P + F L V+ GG YTC
Sbjct: 241 KLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCS-G 299
Query: 283 LHDNQNGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEGARFALVR 338
++ + WS S P++++++ + P S P SG + L C + F L +
Sbjct: 300 AYNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTK 359
Query: 339 ED--------RGGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSE 390
E + R+ H++Q A F + ++ A + Y C P+ + PS+
Sbjct: 360 EGAADSPLRLKSKRQSHKYQ------AEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSD 413
Query: 391 RLELHVDG 398
LEL V G
Sbjct: 414 PLELVVSG 421
Score = 65.5 bits (158), Expect = 1e-10
Identities = 80/300 (26%), Positives = 124/300 (41%), Gaps = 23/300 (7%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELL----VPRSSTSPDRIF 263
P P L E V+ G+ VTL C L ++ L R +K L +P+ +
Sbjct: 27 PKPTLW--AEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQ-- 82
Query: 264 FHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELIL----SDETLPAPEFSPEPESGR 319
F + ++ G Y C Y H G S S P+EL++ S TL A SP SG
Sbjct: 83 FPILSITWEHAGRYCCIYGSHTV--GLSESSDPLELVVTGAYSKPTLSALP-SPVVTSGG 139
Query: 320 ALRLRCLAPLEGARFALVRE--DRGGRRVHRFQSPAGTE-ALFELHNISVADSANYSCVY 376
+ ++C + + F L +E D + ++ G+ A+F + +S + +Y C
Sbjct: 140 NVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYG 199
Query: 377 VDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLR 436
D + P+ S PS+ L L V G +P L V G +C F L +
Sbjct: 200 YDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSDAGYDRFVLYK 259
Query: 437 E-GETKAVKTVRTPGAA---ANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
E G + R P A AN L V + G Y C ++ + S SDP+++L+
Sbjct: 260 EWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCS-GAYNLSSEWSAPSDPLDILI 318
Score = 48.5 bits (114), Expect = 1e-05
Identities = 35/99 (35%), Positives = 48/99 (48%), Gaps = 8/99 (8%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPG---AAAN 454
GP P+P L A + G LRC+G + + L RE +T A+ R P
Sbjct: 24 GPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKT-ALWITRIPQELVKKGQ 82
Query: 455 LELIFVGPQHAGNYRCRYRSWVPHTFE-SELSDPVELLV 492
++ + +HAG Y C Y S HT SE SDP+EL+V
Sbjct: 83 FPILSITWEHAGRYCCIYGS---HTVGLSESSDPLELVV 118
>gi|208879429 hypothetical LOC441864 [Homo sapiens]
Length = 271
Score = 82.8 bits (203), Expect = 7e-16
Identities = 78/247 (31%), Positives = 111/247 (44%), Gaps = 34/247 (13%)
Query: 186 TDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRR 245
T G+G+L +PS L+A P S V+ + VTL C P GV F LR+
Sbjct: 20 TRGDGSLPKPS-------LSAWP----------SSVVPANSNVTLRCWTPARGVSFVLRK 62
Query: 246 GEKELLVPRSSTSPDRIF-FHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELI---- 300
G L P+ S + FHLN + + + G YTC Y + + S S + L+
Sbjct: 63 GGIILESPKPLDSTEGAAEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGH 122
Query: 301 LSDETLPAPEFSPEPESGRALRLRC------LAPLEGARFALVREDRGGRRVHRFQSPAG 354
LS L + GR + L+C P+ FAL++ G + QSPAG
Sbjct: 123 LSKPFLRTYQRGTVTAGGR-VTLQCQKRDQLFVPI---MFALLKA--GTPSPIQLQSPAG 176
Query: 355 TEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVL 414
E F L +++ D+ NYSC+Y K PF S PS++LE+ V PP + V
Sbjct: 177 KEIDFSLVDVTAGDAGNYSCMYYQTKSPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVR 236
Query: 415 AGRDAVL 421
G AV+
Sbjct: 237 LGLAAVI 243
Score = 73.6 bits (179), Expect = 4e-13
Identities = 62/199 (31%), Positives = 85/199 (42%), Gaps = 12/199 (6%)
Query: 303 DETLPAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTE-- 356
D +LP P S P S + LRC P G F L +GG + + TE
Sbjct: 23 DGSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVL---RKGGIILESPKPLDSTEGA 79
Query: 357 ALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAG 416
A F L+N+ V ++ Y+C Y P S S+ L L V G +P LR G V AG
Sbjct: 80 AEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAG 139
Query: 417 RDAVLRCEGP---IPDVTFELLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYR 473
L+C+ + F LL+ G ++ G + L+ V AGNY C Y
Sbjct: 140 GRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYY 199
Query: 474 SWVPHTFESELSDPVELLV 492
+ SE SD +E+LV
Sbjct: 200 QTKSPFWASEPSDQLEILV 218
Score = 53.9 bits (128), Expect = 3e-07
Identities = 69/257 (26%), Positives = 99/257 (38%), Gaps = 22/257 (8%)
Query: 112 GPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEAT 171
G SLP P LS P S + T C RGV+F+LR+ G LE P+ + E
Sbjct: 22 GDGSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGG--IILESPKPLDSTEGA 79
Query: 172 FPVH-------QPGNYSCS-YRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLH 223
H G Y+C YR LS+ S + + P L + + +
Sbjct: 80 AEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGT--VT 137
Query: 224 PGNKVTLTCVAP---LSGVDFQLRRGEKELLVPRSSTSPDRIFFHLNAVALGDGGHYTCR 280
G +VTL C + F L + + S + I F L V GD G+Y+C
Sbjct: 138 AGGRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCM 197
Query: 281 YRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEPESGRALRLRCLAPLEGARFALVRED 340
Y + S S +E+++ T+P S G +RL A + A + E
Sbjct: 198 YYQTKSPFWASEPSDQLEILV---TVPPGTTSSNYSLGNFVRLGLAAVIVVIMGAFLVEA 254
Query: 341 RGGRRVHRFQSPAGTEA 357
R V SP +EA
Sbjct: 255 WYSRNV----SPGESEA 267
Score = 41.6 bits (96), Expect = 0.002
Identities = 62/222 (27%), Positives = 88/222 (39%), Gaps = 23/222 (10%)
Query: 28 QPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQE-PVHLDSPAIKHQFLLTG- 85
+PSL A S++ +NVTL C F L K G+ E P LDS +F L
Sbjct: 28 KPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGAAEFHLNNL 87
Query: 86 --DTQGRYRC---RSGLSTGWTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCR 140
G Y C R +Q S +L L L P+L +T G + T C+
Sbjct: 88 KVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVTLQCQ 147
Query: 141 ---GVLRGVTFLLRREGDHEFLEVPE-AQEDVEATF---PVHQPGNYSCS-YRTDGEGAL 192
+ + F L + G +++ A ++++ + GNYSC Y+T
Sbjct: 148 KRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTKSPFWA 207
Query: 193 SEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVA 234
SEPS +E L PP G +S GN V L A
Sbjct: 208 SEPSD--QLEILVTVPP------GTTSSNYSLGNFVRLGLAA 241
>gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 3 [Homo sapiens]
Length = 491
Score = 80.5 bits (197), Expect = 3e-15
Identities = 90/337 (26%), Positives = 139/337 (41%), Gaps = 24/337 (7%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
M++ + L+ G++ GP T +P+LWAE S++ VTL CQ LET +++L
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 FKNGVA-----QEPVHLDSPAIKHQFLLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKS 115
K G+ Q P+ + A H D+ GRYRC GW++ S LEL
Sbjct: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120
Query: 116 LPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDV---EATF 172
P L + S + G T CR + F+L +EG+H+ ++ Q +A F
Sbjct: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANF 180
Query: 173 ---PVHQP--GNYSCSYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNK 227
PV + G Y C + S PS + I +A P + + + G
Sbjct: 181 TLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDI-LIAGLIPDIPALSVQPGPKVASGEN 239
Query: 228 VTLTCVAPLSGVD--FQLRRGEKE---LLVPRSSTSPDRIFFHLNAVALGDGGHYTCRYR 282
VTL C + +D F + G L + + + F ++ V GG Y C
Sbjct: 240 VTLLCQS-WHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSA 298
Query: 283 LHDNQNGWSGDSAPVELILS----DETLPAPEFSPEP 315
+ S S P EL++S D +L +P P
Sbjct: 299 IRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTP 335
Score = 73.2 bits (178), Expect = 5e-13
Identities = 88/325 (27%), Positives = 128/325 (39%), Gaps = 35/325 (10%)
Query: 115 SLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFP- 173
+LP P L P S I G T C+G L + L +EG +P A++ P
Sbjct: 25 TLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG------LPWARKRQNPLEPG 78
Query: 174 ----VHQP-------GNYSCSYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVL 222
H P G Y C Y T SEPS + + P L+ V+
Sbjct: 79 AKAKFHIPSTVYDSAGRYRCYYETPA--GWSEPSDPLELVATGVSRKPSLLI--PQGSVV 134
Query: 223 HPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPD----RIFFHLNAVALGDGGHYT 278
G +TL C + + F L + + LV S P + F L V+ GG Y
Sbjct: 135 ARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYR 194
Query: 279 CRYRLHDNQNGWSGDSAPVELILSD--ETLPAPEFSPEPE--SGRALRLRCLAPLEGARF 334
C Y H+ WS S P++++++ +PA P P+ SG + L C + + F
Sbjct: 195 C-YGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTF 253
Query: 335 ALVREDRGGRRV---HRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSER 391
L +E + ++QS +A F + ++ A Y C P+ S+PS
Sbjct: 254 FLTKEGAAHPPLCLKSKYQSYRH-QAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYP 312
Query: 392 LELHVDGPPPRPQLRATWSGAVLAG 416
EL V GP P L T S AG
Sbjct: 313 QELVVSGPSGDPSLSPTGSTPTPAG 337
Score = 71.2 bits (173), Expect = 2e-12
Identities = 61/197 (30%), Positives = 84/197 (42%), Gaps = 12/197 (6%)
Query: 305 TLPAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFE 360
TLP P EP S G+ + L C PLE + L +E R + G +A F
Sbjct: 25 TLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKFH 84
Query: 361 LHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAV 420
+ + + Y C Y + P G S PS+ LEL G +P L V G
Sbjct: 85 IPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGGSLT 141
Query: 421 LRCEGPIPDVTFELLREGETKAVK-TVRTPGAA---ANLELIFVGPQHAGNYRCRYRSWV 476
L+C + F L +EGE V+ + + P A AN L V H G YRC Y +
Sbjct: 142 LQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHN 200
Query: 477 PHTFESELSDPVELLVA 493
S SDP+++L+A
Sbjct: 201 LSPRWSAPSDPLDILIA 217
Score = 45.8 bits (107), Expect = 9e-05
Identities = 33/99 (33%), Positives = 45/99 (45%), Gaps = 11/99 (11%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVR--TPGAAANL 455
G P+P L A + + G+ L C+GP+ + L +EG A K PGA A
Sbjct: 24 GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83
Query: 456 ELIFVGPQHAGNYRCRYRS---WVPHTFESELSDPVELL 491
+ AG YRC Y + W SE SDP+EL+
Sbjct: 84 HIPSTVYDSAGRYRCYYETPAGW------SEPSDPLELV 116
>gi|46488946 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 3 [Homo sapiens]
Length = 410
Score = 76.6 bits (187), Expect = 5e-14
Identities = 84/284 (29%), Positives = 125/284 (44%), Gaps = 18/284 (6%)
Query: 221 VLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIFFHLNAVALGDGGHYTCR 280
V+ G VTL C + L +F L + E + VP R F + V G Y C
Sbjct: 38 VVSEGQHVTLQCRSRLGFNEFSLSK-EDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCC 96
Query: 281 YRLHDNQNGWSGDSAPVELILSD-ETLPAPEFSPEP--ESGRALRLRCLAPLEGARFALV 337
+ GWS S PV ++++ P+ P P +SG + L+C + + RF L
Sbjct: 97 SSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLH 156
Query: 338 RED--RGGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELH 395
RE R+ AG++ + + ++ A + Y C P+ SAPS+ L++
Sbjct: 157 REGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIV 216
Query: 396 VDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLRE---GETKAVKTVRTPGA- 451
V G +P L A V AG + L C + L RE GE + +R G
Sbjct: 217 VVGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTF 276
Query: 452 AANLELIFVGP-QHAGNYRC--RYRSWVPHTFESELSDPVELLV 492
AN L GP H GNYRC +R+ +PH + S+ SDP+ + V
Sbjct: 277 QANFPL---GPVTHGGNYRCFGSFRA-LPHAW-SDPSDPLPVSV 315
Score = 37.0 bits (84), Expect = 0.041
Identities = 46/188 (24%), Positives = 65/188 (34%), Gaps = 16/188 (8%)
Query: 11 WGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQEPV 70
W PV +PSL A L+K V L C + + F L + G+ ++P+
Sbjct: 106 WSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPL 165
Query: 71 HL-------DSPAIKHQFLLTGDTQGRYRCRSGLSTGWTQL---SKLLELTGPKSLPAPW 120
L S +T G YRC ++ +L S L++ P
Sbjct: 166 RLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPS 225
Query: 121 LSMAPVSWITPGLKTTAVCRGVLRGVTFLLRRE---GDHEFLEVPEAQEDVEATF---PV 174
LS P + G T C + L RE G+ V +A F PV
Sbjct: 226 LSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV 285
Query: 175 HQPGNYSC 182
GNY C
Sbjct: 286 THGGNYRC 293
Score = 36.6 bits (83), Expect = 0.054
Identities = 69/297 (23%), Positives = 106/297 (35%), Gaps = 25/297 (8%)
Query: 119 PWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDV-------EAT 171
P+LS P + ++ G T CR L F L +E + + VPE +
Sbjct: 29 PFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKE---DGMPVPELYNRIFRNSFLMGPV 85
Query: 172 FPVHQPGNYSCSYRTDGEGALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLT 231
P H CS S PS V I P L+ H ++ G V L
Sbjct: 86 TPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAH--PGPLVKSGETVILQ 143
Query: 232 CVAPLSGVDFQLRR----GEKELLVPRSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQ 287
C + + F L R + LV + + ++ + + + G Y C +
Sbjct: 144 CWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLP 203
Query: 288 NGWSGDSAPVELILSDETLPAPEFSPEP----ESGRALRLRCLAPLEGARFALVREDRGG 343
S S P+++++ P S +P ++G + L C + + L RE G
Sbjct: 204 YELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAG 262
Query: 344 R-RVHRFQSPAGT-EALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDG 398
R+ GT +A F L V NY C P S PS+ L + V G
Sbjct: 263 ELRLTAVLRVNGTFQANFPLG--PVTHGGNYRCFGSFRALPHAWSDPSDPLPVSVTG 317
>gi|32895361 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 3 [Homo sapiens]
Length = 265
Score = 76.6 bits (187), Expect = 5e-14
Identities = 59/184 (32%), Positives = 87/184 (47%), Gaps = 11/184 (5%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
+S ++ LL G++ GP T ++ +LWAE S++ +VT+ CQ LE +++L
Sbjct: 19 VSPALMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 78
Query: 61 FKNGVAQEPVHLDSPAI---KHQFLLTGDTQ---GRYRCRSGLSTGWTQLSKLLELTGPK 114
K G + EP +P K +F + T+ GRYRC GW++ S LEL
Sbjct: 79 VKEG-SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTG 137
Query: 115 SLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQ----EDVEA 170
P LS P +T G T C LR F+L EGDH+ ++Q +A
Sbjct: 138 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 197
Query: 171 TFPV 174
FPV
Sbjct: 198 LFPV 201
Score = 52.0 bits (123), Expect = 1e-06
Identities = 46/160 (28%), Positives = 70/160 (43%), Gaps = 12/160 (7%)
Query: 318 GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAG--TEALFELHNISVADSANYSCV 375
G ++ +RC LE + LV+E G Q+P +A F + +++ + Y C
Sbjct: 60 GNSVTIRCQGTLEAQEYRLVKE--GSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY 117
Query: 376 YVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELL 435
Y P G S PS+ LEL V G +P L A S V +G + L+C + F L
Sbjct: 118 YYS---PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILT 174
Query: 436 REGETKAVKTVRTP-GAAANLELIF----VGPQHAGNYRC 470
EG+ K T+ + + + +F V P H RC
Sbjct: 175 EEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRC 214
Score = 44.3 bits (103), Expect = 3e-04
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Query: 217 ESSQVLHPGNKVTLTCVAPLSGVDFQL-RRGEKELLVPRSSTSP-DRIFFHLNAVALGDG 274
E V+ GN VT+ C L +++L + G E ++ P ++ F + ++
Sbjct: 52 EPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHA 111
Query: 275 GHYTCRYRLHDNQNGWSGDSAPVELIL----SDETLPAPEFSPEPESGRALRLRCLAPLE 330
G Y C Y + GWS S P+EL++ + TL A SP SG + L+C + L
Sbjct: 112 GRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALP-SPVVTSGENVTLQCGSRLR 167
Query: 331 GARFALVRE 339
RF L E
Sbjct: 168 FDRFILTEE 176
Score = 42.0 bits (97), Expect = 0.001
Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 12/88 (13%)
Query: 411 GAVLA-GRDAVLRCEGPIPDVTFELLREGETKAVKTVRT--PGAAANLELIFVGPQHAGN 467
G+V++ G +RC+G + + L++EG + T P A + + HAG
Sbjct: 54 GSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGR 113
Query: 468 YRCRYRS---WVPHTFESELSDPVELLV 492
YRC Y S W SE SDP+EL+V
Sbjct: 114 YRCYYYSPAGW------SEPSDPLELVV 135
>gi|32490553 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 1 [Homo sapiens]
Length = 299
Score = 76.6 bits (187), Expect = 5e-14
Identities = 59/184 (32%), Positives = 87/184 (47%), Gaps = 11/184 (5%)
Query: 1 MSMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
+S ++ LL G++ GP T ++ +LWAE S++ +VT+ CQ LE +++L
Sbjct: 19 VSPALMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 78
Query: 61 FKNGVAQEPVHLDSPAI---KHQFLLTGDTQ---GRYRCRSGLSTGWTQLSKLLELTGPK 114
K G + EP +P K +F + T+ GRYRC GW++ S LEL
Sbjct: 79 VKEG-SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTG 137
Query: 115 SLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQ----EDVEA 170
P LS P +T G T C LR F+L EGDH+ ++Q +A
Sbjct: 138 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 197
Query: 171 TFPV 174
FPV
Sbjct: 198 LFPV 201
Score = 52.0 bits (123), Expect = 1e-06
Identities = 46/160 (28%), Positives = 70/160 (43%), Gaps = 12/160 (7%)
Query: 318 GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAG--TEALFELHNISVADSANYSCV 375
G ++ +RC LE + LV+E G Q+P +A F + +++ + Y C
Sbjct: 60 GNSVTIRCQGTLEAQEYRLVKE--GSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY 117
Query: 376 YVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELL 435
Y P G S PS+ LEL V G +P L A S V +G + L+C + F L
Sbjct: 118 YYS---PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILT 174
Query: 436 REGETKAVKTVRTP-GAAANLELIF----VGPQHAGNYRC 470
EG+ K T+ + + + +F V P H RC
Sbjct: 175 EEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRC 214
Score = 44.3 bits (103), Expect = 3e-04
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Query: 217 ESSQVLHPGNKVTLTCVAPLSGVDFQL-RRGEKELLVPRSSTSP-DRIFFHLNAVALGDG 274
E V+ GN VT+ C L +++L + G E ++ P ++ F + ++
Sbjct: 52 EPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHA 111
Query: 275 GHYTCRYRLHDNQNGWSGDSAPVELIL----SDETLPAPEFSPEPESGRALRLRCLAPLE 330
G Y C Y + GWS S P+EL++ + TL A SP SG + L+C + L
Sbjct: 112 GRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALP-SPVVTSGENVTLQCGSRLR 167
Query: 331 GARFALVRE 339
RF L E
Sbjct: 168 FDRFILTEE 176
Score = 42.0 bits (97), Expect = 0.001
Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 12/88 (13%)
Query: 411 GAVLA-GRDAVLRCEGPIPDVTFELLREGETKAVKTVRT--PGAAANLELIFVGPQHAGN 467
G+V++ G +RC+G + + L++EG + T P A + + HAG
Sbjct: 54 GSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGR 113
Query: 468 YRCRYRS---WVPHTFESELSDPVELLV 492
YRC Y S W SE SDP+EL+V
Sbjct: 114 YRCYYYSPAGW------SEPSDPLELVV 135
>gi|45580719 osteoclast-associated receptor isoform 1 [Homo sapiens]
Length = 286
Score = 75.5 bits (184), Expect = 1e-13
Identities = 70/240 (29%), Positives = 101/240 (42%), Gaps = 33/240 (13%)
Query: 3 MLVVFLLLWGVTWGPVTEAAIF------YETQPSLWAESESLLKPLANVTLTCQAHLETP 56
+++ L LW + +T + Y +P L A+ +++ P NVTL C+A
Sbjct: 5 LILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAW 64
Query: 57 DFQLFKNGVAQEPVHLDSPAIKHQFLLTGDTQ---GRYRC---RSGLSTG-WTQLSKLLE 109
F LFK G + D + +F L T G YRC R G W+Q S +LE
Sbjct: 65 RFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLE 124
Query: 110 LTGPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEV-PEAQEDV 168
L + LP P L P + PG + C G LR ++F+L REG L+ AQ
Sbjct: 125 LLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA 184
Query: 169 EAT-FPVHQPGNYSCSYRT------------------DGEGALSEPSATVTIEELAAPPP 209
+ T PG YSC Y T +GEG + P+++ + PPP
Sbjct: 185 DFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEGEGPEARPASSAPGMQAPGPPP 244
Score = 62.4 bits (150), Expect = 9e-10
Identities = 70/217 (32%), Positives = 92/217 (42%), Gaps = 16/217 (7%)
Query: 195 PSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQL-RRGEKELLVP 253
PS + + + P P L + + V+ PG VTL C AP F L + GE L+
Sbjct: 22 PSVAIIVPPASYHPKPWL--GAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLF 79
Query: 254 RSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQNG-WSGDSAPVELILSDETLPAPEF- 311
R +S FF L V GG Y C YR D G WS S +EL++++E LP P
Sbjct: 80 RDVSSELAEFF-LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEE-LPRPSLV 137
Query: 312 ---SPEPESGRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFELHNISVAD 368
P G + LRC L F L RE G +++ A A F L +
Sbjct: 138 ALPGPVVGPGANVSLRCAGRLRNMSFVLYRE--GVAAPLQYRHSAQPWADFTL--LGARA 193
Query: 369 SANYSCVYVDLKPPFGGSAPSERLEL--HVDGPPPRP 403
YSC Y P+ S SE L + +GP RP
Sbjct: 194 PGTYSCYYHTPSAPYVLSQRSEVLVISWEGEGPEARP 230
Score = 58.2 bits (139), Expect = 2e-08
Identities = 53/175 (30%), Positives = 76/175 (43%), Gaps = 13/175 (7%)
Query: 307 PAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFELH 362
P P +P + G + LRC AP RF L + G F+ + A F L
Sbjct: 35 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKP--GEIAPLLFRDVSSELAEFFLE 92
Query: 363 NISVADSANYSCVYVDLKPPFGG---SAPSERLELHVDGPPPRPQLRATWSGAVLAGRDA 419
++ A Y C Y +P +G S PS+ LEL V PRP L A V G +
Sbjct: 93 EVTPAQGGIYRCCY--RRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 150
Query: 420 VLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRS 474
LRC G + +++F L REG ++ + A+ L+ G + G Y C Y +
Sbjct: 151 SLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLL--GARAPGTYSCYYHT 203
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/96 (36%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Query: 401 PRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFV 460
P+P L A + V G + LRC P P F L + GE + A L V
Sbjct: 35 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 94
Query: 461 GPQHAGNYRCRYR--SWVPHTFESELSDPVELLVAE 494
P G YRC YR W P + S+ SD +ELLV E
Sbjct: 95 TPAQGGIYRCCYRRPDWGPGVW-SQPSDVLELLVTE 129
>gi|134268644 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 1 precursor [Homo
sapiens]
Length = 444
Score = 72.4 bits (176), Expect = 9e-13
Identities = 74/278 (26%), Positives = 119/278 (42%), Gaps = 10/278 (3%)
Query: 219 SQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIFFHLNAVALGDGGHYT 278
S V+ G VTL C +F L + E + +P + F+++ V G+YT
Sbjct: 36 SAVVPRGGHVTLRCHYRHRFNNFMLYK-EDRIHIPIFHGRIFQESFNMSPVTTAHAGNYT 94
Query: 279 CRYRLHDNQNGWSGDSAPVELILS-DETLPAPEFSPEP--ESGRALRLRCLAPLEGARFA 335
CR + GWS S PV ++++ + P+ P P +SG + L+C + + F
Sbjct: 95 CRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFF 154
Query: 336 LVRE--DRGGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLE 393
L +E + R+ ++A F + + +A + Y C P+ SAPS+ L+
Sbjct: 155 LHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLD 214
Query: 394 LHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREG--ETKAVKTVRTPGA 451
+ V GP +P L A V AG L C + L REG + + VR
Sbjct: 215 IVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNR 274
Query: 452 AANLELIFVGPQHAGNYRCRYRSWVPHTFE-SELSDPV 488
+ H G YRC + S+ +E S+ SDP+
Sbjct: 275 TFQADFPLGPATHGGTYRC-FGSFRHSPYEWSDPSDPL 311
Score = 39.3 bits (90), Expect = 0.008
Identities = 49/193 (25%), Positives = 71/193 (36%), Gaps = 18/193 (9%)
Query: 11 WGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQEPV 70
W PV +PSL A L+K V L C + + F L K G++++P
Sbjct: 106 WSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPS 165
Query: 71 HL----DSPAIKHQFLLTG---DTQGRYRCRSGLSTGWTQLSKL-----LELTGPKSLPA 118
L K F + G YRC ++ QLS + +TGP P+
Sbjct: 166 RLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPS 225
Query: 119 PWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREG---DHEFLEVPEAQEDVEATFPVH 175
LS P + G T C + L REG + V + +A FP+
Sbjct: 226 --LSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPL- 282
Query: 176 QPGNYSCSYRTDG 188
P + +YR G
Sbjct: 283 GPATHGGTYRCFG 295
>gi|19557668 osteoclast-associated receptor isoform 4 [Homo sapiens]
Length = 263
Score = 72.0 bits (175), Expect = 1e-12
Identities = 63/195 (32%), Positives = 88/195 (45%), Gaps = 11/195 (5%)
Query: 3 MLVVFLLLWGVTWGPVTEAA--IFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQL 60
+++ L LW + +T + Y +P L A+ +++ P NVTL C+A F L
Sbjct: 5 LILQLLTLWPLCHTDITPSVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGL 64
Query: 61 FKNGVAQEPVHLDSPAIKHQFLLTGDTQ---GRYRC---RSGLSTG-WTQLSKLLELTGP 113
FK G + D + +F L T G YRC R G W+Q S +LEL
Sbjct: 65 FKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVT 124
Query: 114 KSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEV-PEAQEDVEAT- 171
+ LP P L P + PG + C G LR ++F+L REG L+ AQ + T
Sbjct: 125 EELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL 184
Query: 172 FPVHQPGNYSCSYRT 186
PG YSC Y T
Sbjct: 185 LGARAPGTYSCYYHT 199
Score = 58.2 bits (139), Expect = 2e-08
Identities = 53/175 (30%), Positives = 76/175 (43%), Gaps = 13/175 (7%)
Query: 307 PAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFELH 362
P P +P + G + LRC AP RF L + G F+ + A F L
Sbjct: 31 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKP--GEIAPLLFRDVSSELAEFFLE 88
Query: 363 NISVADSANYSCVYVDLKPPFGG---SAPSERLELHVDGPPPRPQLRATWSGAVLAGRDA 419
++ A Y C Y +P +G S PS+ LEL V PRP L A V G +
Sbjct: 89 EVTPAQGGIYRCCY--RRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 146
Query: 420 VLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRS 474
LRC G + +++F L REG ++ + A+ L+ G + G Y C Y +
Sbjct: 147 SLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLL--GARAPGTYSCYYHT 199
Score = 55.8 bits (133), Expect = 9e-08
Identities = 64/195 (32%), Positives = 81/195 (41%), Gaps = 17/195 (8%)
Query: 209 PPVLMHH-----GESSQVLHPGNKVTLTCVAPLSGVDFQL-RRGEKELLVPRSSTSPDRI 262
PP H + + V+ PG VTL C AP F L + GE L+ R +S
Sbjct: 25 PPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAE 84
Query: 263 FFHLNAVALGDGGHYTCRYRLHDNQNG-WSGDSAPVELILSDETLPAPEF----SPEPES 317
FF L V GG Y C YR D G WS S +EL++++E LP P P
Sbjct: 85 FF-LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEE-LPRPSLVALPGPVVGP 142
Query: 318 GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFELHNISVADSANYSCVYV 377
G + LRC L F L RE G +++ A A F L + YSC Y
Sbjct: 143 GANVSLRCAGRLRNMSFVLYRE--GVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYH 198
Query: 378 DLKPPFGGSAPSERL 392
P+ S SE L
Sbjct: 199 TPSAPYVLSQRSEVL 213
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/96 (36%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Query: 401 PRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFV 460
P+P L A + V G + LRC P P F L + GE + A L V
Sbjct: 31 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 90
Query: 461 GPQHAGNYRCRYR--SWVPHTFESELSDPVELLVAE 494
P G YRC YR W P + S+ SD +ELLV E
Sbjct: 91 TPAQGGIYRCCYRRPDWGPGVW-SQPSDVLELLVTE 125
>gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B,
member 4 isoform 2 [Homo sapiens]
Length = 447
Score = 71.6 bits (174), Expect = 2e-12
Identities = 57/198 (28%), Positives = 86/198 (43%), Gaps = 11/198 (5%)
Query: 306 LPAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFEL 361
LP P EP S G ++ + C LE + L +E+ + +A F +
Sbjct: 26 LPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFSI 85
Query: 362 HNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVL 421
+++ + Y C Y + P G S PS+ LEL + G +P L A S V +G+ L
Sbjct: 86 PSMTEDYAGRYRCYY---RSPVGWSQPSDPLELVMTGAYSKPTLSALPSPLVTSGKSVTL 142
Query: 422 RCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIF----VGPQHAGNYRCRYRSWVP 477
C+ P TF L++E + +R+ A + F V H G YRC
Sbjct: 143 LCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSHGFS 202
Query: 478 HTFESELSDPVELLVAES 495
H S SDP+EL+V+ S
Sbjct: 203 HYLLSHPSDPLELIVSGS 220
Score = 69.7 bits (169), Expect = 6e-12
Identities = 71/243 (29%), Positives = 102/243 (41%), Gaps = 37/243 (15%)
Query: 8 LLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQ 67
LL G++ GP T +P+LWAE S++ +VT+ CQ LE +++L K +
Sbjct: 8 LLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKE---E 64
Query: 68 EPVHLD-----SPAIKHQFLL---TGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLPAP 119
P D P K +F + T D GRYRC GW+Q S LEL + P
Sbjct: 65 SPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYSKP 124
Query: 120 WLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRRE-GDHEFLEV--PEAQEDVEATFPV-- 174
LS P +T G T +C+ TFLL +E H L + + +A FP+
Sbjct: 125 TLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSP 184
Query: 175 --------------HQPGNYSCSYRTDG-----EGALSE--PSATVTIEELAAPPPPVLM 213
H +Y S+ +D G+L + PS T ++ A P LM
Sbjct: 185 VTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQPLM 244
Query: 214 HHG 216
G
Sbjct: 245 PTG 247
Score = 57.0 bits (136), Expect = 4e-08
Identities = 64/231 (27%), Positives = 97/231 (41%), Gaps = 17/231 (7%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSS--TSPDRIFFH 265
P P L E V+ GN VT+ C L +++L + E R + ++ F
Sbjct: 27 PKPTLW--AEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFS 84
Query: 266 LNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELIL----SDETLPAPEFSPEPESGRAL 321
+ ++ G Y C YR + GWS S P+EL++ S TL A SP SG+++
Sbjct: 85 IPSMTEDYAGRYRCYYR---SPVGWSQPSDPLELVMTGAYSKPTLSALP-SPLVTSGKSV 140
Query: 322 RLRCLAPLEGARFALVREDRGGRRVHRFQSPAGT---EALFELHNISVADSANYSCVYVD 378
L C + F L++E R + +S G +A F + ++ Y C
Sbjct: 141 TLLCQSRSPMDTFLLIKE-RAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSH 199
Query: 379 LKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAG-RDAVLRCEGPIP 428
+ S PS+ LEL V G P+ T S + AG D L G +P
Sbjct: 200 GFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQPLMPTGSVP 250
Score = 38.5 bits (88), Expect = 0.014
Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAV---KTVRTPGAAAN 454
GP P+P L A + G + C+G + + L +E E+ A + P A
Sbjct: 24 GPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKE-ESPAPWDRQNPLEPKNKAR 82
Query: 455 LELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
+ + +AG YRC YRS V S+ SDP+EL++
Sbjct: 83 FSIPSMTEDYAGRYRCYYRSPVGW---SQPSDPLELVM 117
>gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B,
member 4 isoform 1 [Homo sapiens]
Length = 448
Score = 71.6 bits (174), Expect = 2e-12
Identities = 57/198 (28%), Positives = 86/198 (43%), Gaps = 11/198 (5%)
Query: 306 LPAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFEL 361
LP P EP S G ++ + C LE + L +E+ + +A F +
Sbjct: 26 LPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFSI 85
Query: 362 HNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVL 421
+++ + Y C Y + P G S PS+ LEL + G +P L A S V +G+ L
Sbjct: 86 PSMTEDYAGRYRCYY---RSPVGWSQPSDPLELVMTGAYSKPTLSALPSPLVTSGKSVTL 142
Query: 422 RCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIF----VGPQHAGNYRCRYRSWVP 477
C+ P TF L++E + +R+ A + F V H G YRC
Sbjct: 143 LCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSHGFS 202
Query: 478 HTFESELSDPVELLVAES 495
H S SDP+EL+V+ S
Sbjct: 203 HYLLSHPSDPLELIVSGS 220
Score = 69.7 bits (169), Expect = 6e-12
Identities = 71/243 (29%), Positives = 102/243 (41%), Gaps = 37/243 (15%)
Query: 8 LLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQ 67
LL G++ GP T +P+LWAE S++ +VT+ CQ LE +++L K +
Sbjct: 8 LLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKE---E 64
Query: 68 EPVHLD-----SPAIKHQFLL---TGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLPAP 119
P D P K +F + T D GRYRC GW+Q S LEL + P
Sbjct: 65 SPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYSKP 124
Query: 120 WLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRRE-GDHEFLEV--PEAQEDVEATFPV-- 174
LS P +T G T +C+ TFLL +E H L + + +A FP+
Sbjct: 125 TLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSP 184
Query: 175 --------------HQPGNYSCSYRTDG-----EGALSE--PSATVTIEELAAPPPPVLM 213
H +Y S+ +D G+L + PS T ++ A P LM
Sbjct: 185 VTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQPLM 244
Query: 214 HHG 216
G
Sbjct: 245 PTG 247
Score = 57.0 bits (136), Expect = 4e-08
Identities = 64/231 (27%), Positives = 97/231 (41%), Gaps = 17/231 (7%)
Query: 208 PPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSS--TSPDRIFFH 265
P P L E V+ GN VT+ C L +++L + E R + ++ F
Sbjct: 27 PKPTLW--AEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFS 84
Query: 266 LNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELIL----SDETLPAPEFSPEPESGRAL 321
+ ++ G Y C YR + GWS S P+EL++ S TL A SP SG+++
Sbjct: 85 IPSMTEDYAGRYRCYYR---SPVGWSQPSDPLELVMTGAYSKPTLSALP-SPLVTSGKSV 140
Query: 322 RLRCLAPLEGARFALVREDRGGRRVHRFQSPAGT---EALFELHNISVADSANYSCVYVD 378
L C + F L++E R + +S G +A F + ++ Y C
Sbjct: 141 TLLCQSRSPMDTFLLIKE-RAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSH 199
Query: 379 LKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAG-RDAVLRCEGPIP 428
+ S PS+ LEL V G P+ T S + AG D L G +P
Sbjct: 200 GFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQPLMPTGSVP 250
Score = 38.5 bits (88), Expect = 0.014
Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 398 GPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAV---KTVRTPGAAAN 454
GP P+P L A + G + C+G + + L +E E+ A + P A
Sbjct: 24 GPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKE-ESPAPWDRQNPLEPKNKAR 82
Query: 455 LELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLV 492
+ + +AG YRC YRS V S+ SDP+EL++
Sbjct: 83 FSIPSMTEDYAGRYRCYYRSPVGW---SQPSDPLELVM 117
>gi|45580713 osteoclast-associated receptor isoform 3 [Homo sapiens]
Length = 267
Score = 71.2 bits (173), Expect = 2e-12
Identities = 63/199 (31%), Positives = 88/199 (44%), Gaps = 15/199 (7%)
Query: 3 MLVVFLLLWGVTWGPVTEAAIF------YETQPSLWAESESLLKPLANVTLTCQAHLETP 56
+++ L LW + +T + Y +P L A+ +++ P NVTL C+A
Sbjct: 5 LILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAW 64
Query: 57 DFQLFKNGVAQEPVHLDSPAIKHQFLLTGDTQ---GRYRC---RSGLSTG-WTQLSKLLE 109
F LFK G + D + +F L T G YRC R G W+Q S +LE
Sbjct: 65 RFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLE 124
Query: 110 LTGPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEV-PEAQEDV 168
L + LP P L P + PG + C G LR ++F+L REG L+ AQ
Sbjct: 125 LLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA 184
Query: 169 EAT-FPVHQPGNYSCSYRT 186
+ T PG YSC Y T
Sbjct: 185 DFTLLGARAPGTYSCYYHT 203
Score = 58.9 bits (141), Expect = 1e-08
Identities = 66/204 (32%), Positives = 86/204 (42%), Gaps = 14/204 (6%)
Query: 195 PSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQL-RRGEKELLVP 253
PS + + + P P L + + V+ PG VTL C AP F L + GE L+
Sbjct: 22 PSVAIIVPPASYHPKPWL--GAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLF 79
Query: 254 RSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQNG-WSGDSAPVELILSDETLPAPEF- 311
R +S FF L V GG Y C YR D G WS S +EL++++E LP P
Sbjct: 80 RDVSSELAEFF-LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEE-LPRPSLV 137
Query: 312 ---SPEPESGRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFELHNISVAD 368
P G + LRC L F L RE G +++ A A F L +
Sbjct: 138 ALPGPVVGPGANVSLRCAGRLRNMSFVLYRE--GVAAPLQYRHSAQPWADFTL--LGARA 193
Query: 369 SANYSCVYVDLKPPFGGSAPSERL 392
YSC Y P+ S SE L
Sbjct: 194 PGTYSCYYHTPSAPYVLSQRSEVL 217
Score = 58.2 bits (139), Expect = 2e-08
Identities = 53/175 (30%), Positives = 76/175 (43%), Gaps = 13/175 (7%)
Query: 307 PAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFELH 362
P P +P + G + LRC AP RF L + G F+ + A F L
Sbjct: 35 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKP--GEIAPLLFRDVSSELAEFFLE 92
Query: 363 NISVADSANYSCVYVDLKPPFGG---SAPSERLELHVDGPPPRPQLRATWSGAVLAGRDA 419
++ A Y C Y +P +G S PS+ LEL V PRP L A V G +
Sbjct: 93 EVTPAQGGIYRCCY--RRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 150
Query: 420 VLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRS 474
LRC G + +++F L REG ++ + A+ L+ G + G Y C Y +
Sbjct: 151 SLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLL--GARAPGTYSCYYHT 203
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/96 (36%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Query: 401 PRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFV 460
P+P L A + V G + LRC P P F L + GE + A L V
Sbjct: 35 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 94
Query: 461 GPQHAGNYRCRYR--SWVPHTFESELSDPVELLVAE 494
P G YRC YR W P + S+ SD +ELLV E
Sbjct: 95 TPAQGGIYRCCYRRPDWGPGVW-SQPSDVLELLVTE 129
>gi|19557664 osteoclast-associated receptor isoform 5 [Homo sapiens]
Length = 252
Score = 69.7 bits (169), Expect = 6e-12
Identities = 59/171 (34%), Positives = 78/171 (45%), Gaps = 9/171 (5%)
Query: 25 YETQPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQEPVHLDSPAIKHQFLLT 84
Y +P L A+ +++ P NVTL C+A F LFK G + D + +F L
Sbjct: 18 YHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLE 77
Query: 85 GDTQ---GRYRC---RSGLSTG-WTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTA 137
T G YRC R G W+Q S +LEL + LP P L P + PG +
Sbjct: 78 EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137
Query: 138 VCRGVLRGVTFLLRREGDHEFLEV-PEAQEDVEAT-FPVHQPGNYSCSYRT 186
C G LR ++F+L REG L+ AQ + T PG YSC Y T
Sbjct: 138 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPGTYSCYYHT 188
Score = 58.2 bits (139), Expect = 2e-08
Identities = 53/175 (30%), Positives = 76/175 (43%), Gaps = 13/175 (7%)
Query: 307 PAPEFSPEPES----GRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFELH 362
P P +P + G + LRC AP RF L + G F+ + A F L
Sbjct: 20 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKP--GEIAPLLFRDVSSELAEFFLE 77
Query: 363 NISVADSANYSCVYVDLKPPFGG---SAPSERLELHVDGPPPRPQLRATWSGAVLAGRDA 419
++ A Y C Y +P +G S PS+ LEL V PRP L A V G +
Sbjct: 78 EVTPAQGGIYRCCY--RRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 135
Query: 420 VLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRS 474
LRC G + +++F L REG ++ + A+ L+ G + G Y C Y +
Sbjct: 136 SLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLL--GARAPGTYSCYYHT 188
Score = 57.8 bits (138), Expect = 2e-08
Identities = 68/207 (32%), Positives = 86/207 (41%), Gaps = 17/207 (8%)
Query: 197 ATVTIEELAAPPPPVLMHH-----GESSQVLHPGNKVTLTCVAPLSGVDFQL-RRGEKEL 250
A V I +L PP H + + V+ PG VTL C AP F L + GE
Sbjct: 2 ALVLILQLLTLFPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAP 61
Query: 251 LVPRSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQNG-WSGDSAPVELILSDETLPAP 309
L+ R +S FF L V GG Y C YR D G WS S +EL++++E LP P
Sbjct: 62 LLFRDVSSELAEFF-LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEE-LPRP 119
Query: 310 EF----SPEPESGRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFELHNIS 365
P G + LRC L F L RE G +++ A A F L +
Sbjct: 120 SLVALPGPVVGPGANVSLRCAGRLRNMSFVLYRE--GVAAPLQYRHSAQPWADFTL--LG 175
Query: 366 VADSANYSCVYVDLKPPFGGSAPSERL 392
YSC Y P+ S SE L
Sbjct: 176 ARAPGTYSCYYHTPSAPYVLSQRSEVL 202
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/96 (36%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Query: 401 PRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFV 460
P+P L A + V G + LRC P P F L + GE + A L V
Sbjct: 20 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79
Query: 461 GPQHAGNYRCRYR--SWVPHTFESELSDPVELLVAE 494
P G YRC YR W P + S+ SD +ELLV E
Sbjct: 80 TPAQGGIYRCCYRRPDWGPGVW-SQPSDVLELLVTE 114
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,313,963
Number of Sequences: 37866
Number of extensions: 1247076
Number of successful extensions: 4345
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 86
Number of HSP's that attempted gapping in prelim test: 3565
Number of HSP's gapped (non-prelim): 469
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.