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Search of human proteins with 210147567
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|210147567 hypothetical protein LOC220081 [Homo sapiens]
(696 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|210147567 hypothetical protein LOC220081 [Homo sapiens] 1397 0.0
gi|87298939 hypothetical protein LOC131831 [Homo sapiens] 94 6e-19
gi|148746195 trichohyalin [Homo sapiens] 74 3e-13
gi|221219020 NYD-SP11 protein [Homo sapiens] 67 4e-11
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 67 4e-11
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 67 4e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 67 7e-11
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 67 7e-11
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 65 2e-10
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 65 3e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 64 5e-10
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 64 6e-10
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 62 1e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 62 1e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 62 1e-09
gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 62 1e-09
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 61 3e-09
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 61 4e-09
gi|21735415 centromere protein B [Homo sapiens] 59 1e-08
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 59 2e-08
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 58 3e-08
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 58 3e-08
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 58 3e-08
gi|110349719 titin isoform N2-A [Homo sapiens] 57 4e-08
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 57 4e-08
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 57 6e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 57 6e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 57 6e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 57 6e-08
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 57 8e-08
>gi|210147567 hypothetical protein LOC220081 [Homo sapiens]
Length = 696
Score = 1397 bits (3617), Expect = 0.0
Identities = 696/696 (100%), Positives = 696/696 (100%)
Query: 1 MSAENNQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKE 60
MSAENNQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKE
Sbjct: 1 MSAENNQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKE 60
Query: 61 YLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEG 120
YLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEG
Sbjct: 61 YLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEG 120
Query: 121 YLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEK 180
YLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEK
Sbjct: 121 YLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEK 180
Query: 181 ALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTT 240
ALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTT
Sbjct: 181 ALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTT 240
Query: 241 FLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETT 300
FLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETT
Sbjct: 241 FLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETT 300
Query: 301 TKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVF 360
TKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVF
Sbjct: 301 TKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVF 360
Query: 361 KTIIKEMAAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYEKFKETILRIKRRREAQKL 420
KTIIKEMAAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYEKFKETILRIKRRREAQKL
Sbjct: 361 KTIIKEMAAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYEKFKETILRIKRRREAQKL 420
Query: 421 TEMTSFTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLERDKEWIQKKTVVHQGDGKLILY 480
TEMTSFTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLERDKEWIQKKTVVHQGDGKLILY
Sbjct: 421 TEMTSFTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLERDKEWIQKKTVVHQGDGKLILY 480
Query: 481 PNKNVYQILFPDGTGQIHYPSGNLAMLILYAKMKKFTYIILEDSLEGRIRALINNSGNAT 540
PNKNVYQILFPDGTGQIHYPSGNLAMLILYAKMKKFTYIILEDSLEGRIRALINNSGNAT
Sbjct: 481 PNKNVYQILFPDGTGQIHYPSGNLAMLILYAKMKKFTYIILEDSLEGRIRALINNSGNAT 540
Query: 541 FYDENSDIWLNLSSNLGYYFPKDKRQKAWNWWNLNIHVHAPPVQPISLKINEYIQVQIRS 600
FYDENSDIWLNLSSNLGYYFPKDKRQKAWNWWNLNIHVHAPPVQPISLKINEYIQVQIRS
Sbjct: 541 FYDENSDIWLNLSSNLGYYFPKDKRQKAWNWWNLNIHVHAPPVQPISLKINEYIQVQIRS 600
Query: 601 QDKIIFCFTYEQKQICLNLGTRYKFVIPEVLSEMKKKTILEAEPGPTAQKIRVLLGKMNR 660
QDKIIFCFTYEQKQICLNLGTRYKFVIPEVLSEMKKKTILEAEPGPTAQKIRVLLGKMNR
Sbjct: 601 QDKIIFCFTYEQKQICLNLGTRYKFVIPEVLSEMKKKTILEAEPGPTAQKIRVLLGKMNR 660
Query: 661 LLNYATTPDLENFIEAVSISLMDNKYLKKMLSKLWF 696
LLNYATTPDLENFIEAVSISLMDNKYLKKMLSKLWF
Sbjct: 661 LLNYATTPDLENFIEAVSISLMDNKYLKKMLSKLWF 696
>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
Length = 663
Score = 93.6 bits (231), Expect = 6e-19
Identities = 63/210 (30%), Positives = 111/210 (52%), Gaps = 7/210 (3%)
Query: 480 YPNKNVYQILFPDGTGQIHYPSGNLAMLILYAKMKKFTYIILED-SLEGRIRALINNSGN 538
Y + + + FPDGT QI YPSGNLA++ + K+ FT I+ ED I A++++SG
Sbjct: 430 YKHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVNGFTCIVQEDMPTNPAILAVLDSSGR 489
Query: 539 ATFYDENSDIWLNLSSNLGYYFPK-DKRQKAWNWWNLNIHVHAPPVQPISLKINEYIQVQ 597
++ Y N ++W+ ++ G Y + R +AWNW N +P+ L +N YI V+
Sbjct: 490 SSCYHPNGNVWVYINILGGQYSDQAGNRIRAWNWSNSITSSPFVSFKPVFLALNRYIGVR 549
Query: 598 IRSQDKIIFCFTYEQKQICLNLGTRYKFVIPEVLSEMKKKTILEAEPGPTAQKIRVLLGK 657
I QDKI F +Q +++GT+ K PE + ++ + + + KIR L K
Sbjct: 550 ILEQDKISITFLAMGQQARISVGTKVKLPNPEEIPILRYVSGDDLLLLASLIKIRRLFHK 609
Query: 658 MNRLLNYATTPDLE-----NFIEAVSISLM 682
+ +N+ ++ E +++ ++S+ L+
Sbjct: 610 LEGCVNFPSSQVWEKLKQPSYLSSLSLKLI 639
Score = 53.9 bits (128), Expect = 5e-07
Identities = 58/235 (24%), Positives = 104/235 (44%), Gaps = 19/235 (8%)
Query: 133 HLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEE 192
HL G G ++++ EE++ ++ +EEEE ++ EEE+ E+EE + EEE
Sbjct: 3 HLRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEE---EEVEEEEEEVEEEEEEVVEEE 59
Query: 193 ALEKEENLDGKENLYKKYLKEPK--ASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFA- 249
+ +E+ L+ E ++YL + Y +R + PS +TF VP A
Sbjct: 60 LVGEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTF--VPSQSAT 117
Query: 250 ---TPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPE 306
TPS S+T S + +++ + ++ DR ++L +T
Sbjct: 118 STETPSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEESWL-- 175
Query: 307 EHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFK 361
+ ++ KVQ +K+ ASKE + + V + +E+ LN Y+ FK
Sbjct: 176 QDLSDKVQSRKK------ASKEKAEPECLASKLREKWVINPEESKLNILYELEFK 224
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/74 (44%), Positives = 44/74 (59%), Gaps = 7/74 (9%)
Query: 87 GKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYL 146
GK++ E EE LE+ EEEE +EEEE +E EEEE +EE + EEE +G+E L
Sbjct: 14 GKKDQKESEEELEEE---EEEEEVEEEE---EEVEEEEEEVEEEEEEVVEEELVGEEQEL 67
Query: 147 EKEDYIEEVDYLGK 160
E + E +YL K
Sbjct: 68 EAPETFSE-EYLWK 80
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/114 (36%), Positives = 55/114 (48%), Gaps = 29/114 (25%)
Query: 43 LQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAG 102
L+ S F G+ K+ E EE+LEEEE +EEE +EE +EEEE
Sbjct: 4 LRSPSGFGDPGK----KDQKESEEELEEEE--------EEEEVEEEEEEVEEEE------ 45
Query: 103 YLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVD 156
EE EEEE + EEE +G+E+ LE E +E YL K I + D
Sbjct: 46 ----EEVEEEEE------EVVEEELVGEEQELEAPETFSEE-YLWKVTDIGDYD 88
Score = 42.4 bits (98), Expect = 0.001
Identities = 24/64 (37%), Positives = 40/64 (62%), Gaps = 5/64 (7%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLK-----EEE 84
+++++E EL+EE ++E E E++E EEEE++ EEE +G+E+ L+ EE
Sbjct: 17 DQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76
Query: 85 YLGK 88
YL K
Sbjct: 77 YLWK 80
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 15/78 (19%)
Query: 28 PSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLG 87
P +K+ E EE L++E E E E++E +EEEE+ EEE EE + EEE +G
Sbjct: 13 PGKKDQKE---SEEELEEEEE---EEEVEEEEEEVEEEEEEVEEE----EEEVVEEELVG 62
Query: 88 KEEHLE-----EEEYLEK 100
+E+ LE EEYL K
Sbjct: 63 EEQELEAPETFSEEYLWK 80
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 74.3 bits (181), Expect = 3e-13
Identities = 97/465 (20%), Positives = 185/465 (39%), Gaps = 49/465 (10%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEE------EEYLGKEE 78
Q L ++E+ E EE + + + E E + E+EE E+ EE +++
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 79 YLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEE 138
+E+E +E+ L E+ L + L E+ + E+ L +E L E+ L +E+ L E+
Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 423
Query: 139 YLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEE 198
L +E E+ + E + ++ E+EE ++ +L+ E+ E+ E ++ L++++
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEE---RRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 199 NLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESA 258
+ +E K +E + + LR R + Q L +
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLR--REQEERREQ-------RLKRQEEEERLQQR 531
Query: 259 TESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKE 318
S + L RR Q + + R K L+ + EQ + K ++++
Sbjct: 532 LRSEQQL----RREQEERREQLLKREEEKRLE-QERREQRLKREQEERRDQLLKREEERR 586
Query: 319 ENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDFD 378
+ L+ +E + E +++LE E+ E L E EE+
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLK----------------REEPEEERR 630
Query: 379 IPLTKLLESENRWKLVIMLKKNYEKFKETILRIKRRREAQKLTEMTSFTFHLMSKPTPEK 438
L K E E R + L++ ++ +E R+KR E ++L + L + E+
Sbjct: 631 QQLLKSEEQEERRQQ--QLRREQQERREQ--RLKREEEEERLEQ------RLKREHEEER 680
Query: 439 PETEEIQKPQRVVHHRKKLERDKEWIQKKTVVHQGDGKLILYPNK 483
E E ++ Q R K K Q ++ K+ P K
Sbjct: 681 REQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725
Score = 72.4 bits (176), Expect = 1e-12
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 22/205 (10%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLK------EEE 84
++D +++ EE L E P + E K+Y EEEE +EEE L +EE K E +
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQERE-KKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
Query: 85 YLGKEEHLEEEEYL-----EKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEY 139
Y K+E +EEE L EK E E EEE L + EEE+ LG+E +
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ----EEEQLLGEERETRRRQE 1075
Query: 140 LGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEEN 199
L ++ Y ++E+ +E + L L EE ++ E + E+E EEE+ L +E
Sbjct: 1076 LERQ-YRKEEELQQEEEQL-----LREEPEKRRRQERERQCREEEELQQEEEQLLREERE 1129
Query: 200 LDGKENLYKKYLKEPKASYSSQTML 224
++ L ++Y +E + + +L
Sbjct: 1130 KRRRQELERQYREEEEVQQEEEQLL 1154
Score = 70.1 bits (170), Expect = 7e-12
Identities = 91/450 (20%), Positives = 186/450 (41%), Gaps = 51/450 (11%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEE 84
Q L E+++ E + + + E E E +E E+++ E++ +E+ L+ E+
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ 343
Query: 85 YLGKEEHL---EEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLG 141
+E+ L +EEE E+ E+EE E++ L +E L E+ L +E+ L E+ L
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQ-LRREQQLRREQQLRREQQLRREQQLR 402
Query: 142 KEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLD 201
+E L +E L E+ L ++ L E+ E+ E E+E +E+ L
Sbjct: 403 REQQLRREQ------------QLRREQQLRREQQLRREQEEERHEQKHEQE--RREQRLK 448
Query: 202 GKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATES 261
++ + +LK + + + + D + +L + E E
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLE---------EEERREQ 499
Query: 262 SELLLTLYRRSQASQTDWCYDRTAVKS-LKSKSETEQETTTKLAPEEHVNTKVQQKKEEN 320
E RR Q + + R + L+ + +EQ+ + +E ++ +++EE
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE---QEERREQLLKREEEK 556
Query: 321 VLEFASKENFWDGITDESIDKL---EVEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDF 377
LE +E +E D+L E E + + + + + +E E EE
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Query: 378 DIPLTKLLESENRWKLVIMLKKNYEKFKETILRIKRRREAQKLTEMTSFTFHLMSKPTPE 437
+ L + E R + ++ ++ E+ ++ + R ++ R Q+L
Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRL----------------- 659
Query: 438 KPETEEIQKPQRVVHHRKKLERDKEWIQKK 467
K E EE + QR+ ++ R++E +++
Sbjct: 660 KREEEEERLEQRLKREHEEERREQELAEEE 689
Score = 67.4 bits (163), Expect = 4e-11
Identities = 105/462 (22%), Positives = 187/462 (40%), Gaps = 69/462 (14%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEE------------ 78
KE ++ +EE LQ E + ++++Y EEE+ +EEE L +EE
Sbjct: 901 KEQQLLQEEEEELQREEREKRRRQE-QERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 79 -------YLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLE------EE 125
KEE+ LG+E + EK Y EEEE +EEE L +E + E
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKK-YREEEELQQEEEQLLREEREKRRRQEWER 1018
Query: 126 EYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYL-GKKSYLEEEKALE- 183
+Y K+E +EEE L +E ++ E Y ++ +EEE L G++ + LE
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 184 ---KEENLE-EEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVT 239
KEE L+ EEE L +EE + ++ +E + + LLR+ R
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138
Query: 240 TFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQET 299
+ E E +LL + + + + Y + + + E+E
Sbjct: 1139 QY----------REEEEVQQEEEQLLREEPEKRRRQELERQYRE------EEELQQEEEQ 1182
Query: 300 TTKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTV 359
+ E+ + +Q +EE L+ ++ + S K + E EN + +
Sbjct: 1183 LLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN---- 1238
Query: 360 FKTIIKEMAAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYEKFKETILRIKRRREAQK 419
K E E+ + ++L + +++ L +L + E+ +E +RRR Q+
Sbjct: 1239 -----KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQ----ERRRWQQR 1289
Query: 420 LTEMTSFTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLERDK 461
H + E+ E +E ++ R K+L R++
Sbjct: 1290 -------DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324
Score = 63.5 bits (153), Expect = 6e-10
Identities = 53/200 (26%), Positives = 93/200 (46%), Gaps = 13/200 (6%)
Query: 38 LDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLE---- 93
L E+ +++ E E L+ +E + +E +Y +E+ +EEE L +EE +
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ 954
Query: 94 --EEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDY 151
E +Y + ++EE + EE + E++Y +EE +EEE L +E ++
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 152 IEEVDYLGKKAYLEEEEYL-----GKKSYLEEEKALEKEENL--EEEEALEKEENLDGKE 204
E Y K +EEE L K+ E E+ +EE L EEE+ L +E ++
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 205 NLYKKYLKEPKASYSSQTML 224
L ++Y KE + + +L
Sbjct: 1075 ELERQYRKEEELQQEEEQLL 1094
Score = 63.2 bits (152), Expect = 8e-10
Identities = 61/228 (26%), Positives = 104/228 (45%), Gaps = 25/228 (10%)
Query: 27 LPSEKEDTEVELDEESLQDESPFSPEGESLEDKE---YLEEEED--LEEEEYLGKEEYLK 81
LP E+E + + E F E E L+ +E L+EEED E++E +E +
Sbjct: 811 LPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR 870
Query: 82 EEEYLGKEEH--------------LEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEY 127
++++ + E L+E+ E+ EEEE ++ EE + +E +Y
Sbjct: 871 DQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQY 930
Query: 128 LGKEEHLEEEEYLGKEGYLEKEDYIEEVDYL-GKKAYLEEEEYLG----KKSYLEEEKAL 182
+E+ +EEE L +E ++ E Y KK +EE+ LG K+ E EK
Sbjct: 931 REEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 183 EKEENLE-EEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDAR 229
+EE L+ EEE L +EE + +++ ++ + LLR+ R
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038
Score = 60.1 bits (144), Expect = 7e-09
Identities = 103/469 (21%), Positives = 191/469 (40%), Gaps = 53/469 (11%)
Query: 22 YSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEED--LEEEEYLGKEEY 79
+ T+ P E++ EL E + + +D+ + EEEE + E L KEE
Sbjct: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Query: 80 -LKEEEYLGKEEHLEEEEYLEKAG----YLEEEEYIEEEEYLGKEGYL----EEEEYLGK 130
L+EEE + E EEEE L K E +E ++++ L +E L EEE +
Sbjct: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
Query: 131 EEHLEEEEYL-GKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLE 189
EE E++E +E E++ E+ + ++ E+EE ++ E++ +E+ L
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 190 EEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFA 249
E+ L +E+ L ++ L ++ + + L R+ Q+ +
Sbjct: 379 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE--------QQLRREQQLRREQE 430
Query: 250 TPSPVSESATESSELLLTLYRRSQASQTDWC----------YDRTAVKSLKSKSETEQET 299
+ E E L +R Q + DW +R + + + E +E
Sbjct: 431 EERHEQKHEQERREQRL---KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 300 TTKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTV 359
KL EE + QQ++ E L +E ++ + + E E+ + L S Q
Sbjct: 488 WLKLEEEER---REQQERREQQLRREQEER-----REQRLKRQEEEERLQQRLRSEQQLR 539
Query: 360 FKTIIKEMAAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYEKFKETILRIKRRREAQK 419
+ + EE K LE E R + LK+ E+ ++ +L+ + R Q+
Sbjct: 540 REQEERREQLLKREEE-------KRLEQERREQ---RLKREQEERRDQLLKREEERRQQR 589
Query: 420 L-TEMTSFTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLERDKEWIQKK 467
L E + + E+ E EE ++ QR+ + ER ++ ++ +
Sbjct: 590 LKREQEERLEQRLKREEVERLEQEE-RREQRLKREEPEEERRQQLLKSE 637
Score = 58.9 bits (141), Expect = 2e-08
Identities = 53/203 (26%), Positives = 98/203 (48%), Gaps = 21/203 (10%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYL--KEEEYLG 87
E D ++E + + + E E E +E E++E LE+ + ++E L + +E+
Sbjct: 123 EPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQE 182
Query: 88 KEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEE--------------H 133
+EE EEE L+ E EE+ +EE+ +E L E G+EE
Sbjct: 183 REERRAEEEQLQSCKGHETEEFPDEEQLRRRE--LLELRRKGREEKQQQRRERQDRVFQE 240
Query: 134 LEEEEYLGKEGYLEK-EDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEE 192
EE+E+ +E L K E+ ++E + ++ EEEE L K +E E++E ++++
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE--RQELRRERQEEEQQQQ 298
Query: 193 ALEKEENLDGKENLYKKYLKEPK 215
L +E+ L K+ ++ +E +
Sbjct: 299 RLRREQQLRRKQEEERREQQEER 321
Score = 58.5 bits (140), Expect = 2e-08
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 22/204 (10%)
Query: 21 QYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLE---------EEEDLEEE 71
Q Q+L E+++ + E + Q PE E LE +E E EE+ L E
Sbjct: 1264 QQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE 1323
Query: 72 EYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEG---YLEEEEYL 128
E K + + +EE L +E + E + EEE +E +LEEE+ L
Sbjct: 1324 EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRL 1383
Query: 129 GKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGK----KSYLEEEKALEK 184
++E E ++L +E L ++ +++ + + EEE+ L + + + EEE+ + +
Sbjct: 1384 RRQER--ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRR 1441
Query: 185 EEN----LEEEEALEKEENLDGKE 204
+E LEEE+ L +E + +E
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFRE 1465
Score = 53.9 bits (128), Expect = 5e-07
Identities = 54/204 (26%), Positives = 102/204 (50%), Gaps = 32/204 (15%)
Query: 37 ELDEESLQD-ESPFSPEGESLE----DKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEH 91
E +++ QD + F E + L D+++ EEE+ + +E + ++L+EE+ L +E H
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQER--ERKFLEEEQQLRQERH 1460
Query: 92 L---EEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEH---LEEEEYLGKE-- 143
EEE+ L++ EE+ + +E K +LEEE+ L ++E E+E +E
Sbjct: 1461 RKFREEEQLLQE----REEQQLHRQERDRK--FLEEEQQLRRQERDRKFREQELRSQEPE 1514
Query: 144 -GYLEKEDYIEEVDYLGKKAYLEEEEYL-----GKKSYLEEEKALEKEENLEEEEALEKE 197
+LE+E + ++ +L+EE+ L G++ + ++ +EE L +E +E
Sbjct: 1515 RKFLEEEQQLHRQQ--RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE---REE 1569
Query: 198 ENLDGKENLYKKYLKEPKASYSSQ 221
+ L +E K L+E K Q
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQ 1593
Score = 53.1 bits (126), Expect = 8e-07
Identities = 55/209 (26%), Positives = 96/209 (45%), Gaps = 20/209 (9%)
Query: 15 HPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYL 74
H P Q + K +E+ L E D+++ EEE+ L+E E
Sbjct: 1292 HFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE-- 1349
Query: 75 GKEEYLKEEEYLGK--EEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEE 132
E+ L+ +E K EE L +E K +LEEE+ + +E K +L+EE+ L +E
Sbjct: 1350 --EQPLRRQERDRKFREEELRHQEQGRK--FLEEEQRLRRQERERK--FLKEEQQLRCQE 1403
Query: 133 HLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGK----KSYLEEEKAL--EKEE 186
++ + E+E + + + + EEE+ + + + +LEEE+ L E+
Sbjct: 1404 REQQLRQDRDRKFREEEQQLSRQE--RDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
Query: 187 NLEEEEAL--EKEENLDGKENLYKKYLKE 213
EEE L E+EE ++ +K+L+E
Sbjct: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEE 1490
Score = 52.4 bits (124), Expect = 1e-06
Identities = 56/217 (25%), Positives = 97/217 (44%), Gaps = 38/217 (17%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEE 90
+E+ EV+ +EE L E P + LE ++Y EEEE +EEE L +EE K + +E
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELE-RQYREEEELQQEEEQLLREEQEKRRQE--RER 1197
Query: 91 HLEEEEYLE----KAGYLEEEEYIE-------EEEYL---------GKEG----YLEEEE 126
EEE L+ K Y +E++ + E+E G+E LE+ +
Sbjct: 1198 QYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQ 1257
Query: 127 YLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLE--------- 177
++ + + LG++ ++E E + + + EEE L ++ E
Sbjct: 1258 LRDRQSQQDLQHLLGEQQERDREQ--ERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ 1315
Query: 178 EEKALEKEENLEEEEALEKEENLDGKENLYKKYLKEP 214
EEK L +EE E+ E + +E L ++ ++P
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352
Score = 52.0 bits (123), Expect = 2e-06
Identities = 48/206 (23%), Positives = 100/206 (48%), Gaps = 19/206 (9%)
Query: 33 DTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHL 92
+ E +L + Q + + + ED++ L+E E+ + ++L+EE L ++E
Sbjct: 1599 EDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE 1658
Query: 93 EEEEYLEKAGYLEEEEYIE--EEEYLGKE----GYLEEEEYLGKEEHLEEEEYLGKEGYL 146
++ + + EEE+ ++ EE+ L ++ + EEE+ L ++E E ++L +E L
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE--RERKFLQEEQQL 1716
Query: 147 EKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEAL--EKEENLDGKE 204
+++ L +K EEE L +++ E+ + E+ + EEE L E+EE ++
Sbjct: 1717 RRQE-------LERK--FREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQ 1767
Query: 205 NLYKKYLKEPKASYSSQTMLLRDARS 230
+K+ +E + + LR S
Sbjct: 1768 ERDRKFREEEQLRQEREEQQLRSQES 1793
Score = 50.8 bits (120), Expect = 4e-06
Identities = 47/204 (23%), Positives = 97/204 (47%), Gaps = 17/204 (8%)
Query: 24 TQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEE 83
T+ E+ +++ D+E + E E E +++ E++ E+E ++ ++E
Sbjct: 464 TERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE 523
Query: 84 EYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKE 143
E ++ L E+ L + E+ ++ EE E LE+E +E+ L+ E+ ++
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREE----EKRLEQER---REQRLKREQEERRD 576
Query: 144 GYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGK 203
L++E+ + ++ E+EE L ++ EE + LE+EE E+ L++EE +
Sbjct: 577 QLLKREEERRQ-----QRLKREQEERLEQRLKREEVERLEQEE--RREQRLKREE---PE 626
Query: 204 ENLYKKYLKEPKASYSSQTMLLRD 227
E ++ LK + Q L R+
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRRE 650
Score = 50.1 bits (118), Expect = 7e-06
Identities = 53/173 (30%), Positives = 84/173 (48%), Gaps = 26/173 (15%)
Query: 31 KEDTEVELDEESLQD----ESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYL 86
+E E +EE LQ E+ P+ E L +E LE EE+ + E ++ +
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRE---RQDRV 237
Query: 87 GKEEHLEEEEYLEKAGYL-EEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGY 145
+EE EE+E+ ++ L +EEE ++EEE + EEEE L K E E
Sbjct: 238 FQEE--EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQE---------- 285
Query: 146 LEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEE 198
L +E EE ++ L E+ L +K EEE+ ++EE E++E E++E
Sbjct: 286 LRRERQEEE----QQQQRLRREQQLRRKQ--EEERREQQEERREQQERREQQE 332
Score = 50.1 bits (118), Expect = 7e-06
Identities = 47/193 (24%), Positives = 97/193 (50%), Gaps = 24/193 (12%)
Query: 25 QNLPSEKEDTEVELDEESL---QDESPFSPEGESLED---KEYLEEEEDLEE--EEYLGK 76
Q L ++ D + +E+ + + E F E + L +++ EEE+ L+E E+ L +
Sbjct: 1421 QQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR 1480
Query: 77 EE----YLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKE----GYLEEEEYL 128
+E +L+EE+ L ++E + E E +++EEE+ L ++ +L+EE+ L
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQL 1540
Query: 129 GKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEEN- 187
++E ++ + E+E +E ++ L +E +K LEE+K +E+
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQE----REEQQLSRQE-RDRKFRLEEQKVRRQEQER 1595
Query: 188 --LEEEEALEKEE 198
+E+E+ L ++E
Sbjct: 1596 KFMEDEQQLRRQE 1608
Score = 49.7 bits (117), Expect = 9e-06
Identities = 94/450 (20%), Positives = 178/450 (39%), Gaps = 61/450 (13%)
Query: 28 PSEKEDTEVELD-EESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYL 86
P +E E +L EE Q E F PE E E + E + +E ++L +EE L+ E
Sbjct: 788 PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE-KELQFLEEEEQLQRRE-- 844
Query: 87 GKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGY---LEEEEYLGKEEHLEE---EEYL 140
+ + L+EEE G E++E +E + + LEEE + + +E L
Sbjct: 845 -RAQQLQEEE----DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 141 GKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENL 200
KE L +E+ E +K +E+E + Y EEE+ ++EE L EE ++
Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQE----RQYREEEQLQQEEEQLLREEREKRR--- 952
Query: 201 DGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATE 260
++ ++Y K+ K + +L P+ Q E +
Sbjct: 953 --RQERERQYRKDKKLQQKEEQLL---GEEPEKRRRQE----------REKKYREEEELQ 997
Query: 261 SSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPE---EHVNTKVQQKK 317
E L R + + +W + + K E +QE L E + + +Q +
Sbjct: 998 QEEEQLLREEREKRRRQEW------ERQYRKKDELQQEEEQLLREEREKRRLQERERQYR 1051
Query: 318 EENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDF 377
EE L+ ++ + +LE + E L + + + +E E +
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR---EEPEKRRRQERER 1108
Query: 378 DIPLTKLLESENRWKLVIMLKKNYEKFKETILRIKRRREAQKLTEMTSFTFHLMSKPTPE 437
+ L+ E +L++ EK + L + R E + E + + PE
Sbjct: 1109 QCREEEELQQEEEQ----LLREEREKRRRQELERQYREEEEVQQEEEQ-----LLREEPE 1159
Query: 438 KPETEEIQKPQRVVHHRKKLERDKEWIQKK 467
K +E+++ R ++L++++E + ++
Sbjct: 1160 KRRRQELERQYR---EEEELQQEEEQLLRE 1186
Score = 46.6 bits (109), Expect = 8e-05
Identities = 44/187 (23%), Positives = 79/187 (42%), Gaps = 34/187 (18%)
Query: 39 DEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYL 98
D +D+ F P LE++ + +E+E E + EE K+E LE+ +
Sbjct: 112 DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQE----RELAEGEEQSEKQERLEQRDRQ 167
Query: 99 EKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLE-----------EEEYLGKEGYLE 147
+ +EE + ++ + E EE +EE L+ +EE L + LE
Sbjct: 168 RR----------DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLE 217
Query: 148 -----KEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDG 202
+E+ ++ + + EEEE K + + E L KEE +EE +++ L
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEE----KEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 203 KENLYKK 209
+E +K
Sbjct: 274 EEEQLRK 280
Score = 46.2 bits (108), Expect = 1e-04
Identities = 40/197 (20%), Positives = 95/197 (48%), Gaps = 23/197 (11%)
Query: 39 DEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYL 98
+EE L+ E D+++ EE+ + +E + +++++E+ L ++E ++
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ--ERKFMEDEQQLRRQEGQQQLRQE 1616
Query: 99 EKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYL 158
+ E+E+ ++E E E+ L ++E + ++L +E L +++ +++ +
Sbjct: 1617 RDRKFREDEQLLQERE----------EQQLHRQER--DRKFLEEEPQLRRQEREQQLRHD 1664
Query: 159 GKKAYLEEEEYL--GKKSYLEEE----KALEKEENLEEEEALEK---EENLDGKENLYKK 209
+ + EEE+ L G++ L + K E+E+ L +E K EE ++ L +K
Sbjct: 1665 RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERK 1724
Query: 210 YLKEPKASYSSQTMLLR 226
+ +E + ++ LR
Sbjct: 1725 FREEEQLRQETEQEQLR 1741
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 4/138 (2%)
Query: 20 PQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEY 79
P+ Q L ++ D + +EE L+ E D+++ EEE+ +E E
Sbjct: 1757 PEREEQQLRRQERDRKFR-EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQ 1815
Query: 80 LKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEE---HLEE 136
++ +Y +EE L+ EE ++ + +Y EE++ +E EE+ L +EE +E
Sbjct: 1816 QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQE 1875
Query: 137 EEYLGKEGYLEKEDYIEE 154
E +E ++ ++ E+
Sbjct: 1876 RERKLREEHIRRQQKEEQ 1893
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/171 (22%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 30 EKEDTEVELDEESLQDESPFSP--EGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLG 87
E+E E ++E L+ + + E E L + ++ E + +EE L++E
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQER--- 1783
Query: 88 KEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLE 147
+E+ L +E K + EEE+ +E E + +Y +EE L+ EE +
Sbjct: 1784 EEQQLRSQESDRK--FREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQER 1841
Query: 148 KEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEE 198
Y E + ++ EE+ L ++ E+++ E+E L EE +++
Sbjct: 1842 DRQYRAEEQFATQEKSRREEQELWQEE--EQKRRQERERKLREEHIRRQQK 1890
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/208 (24%), Positives = 86/208 (41%), Gaps = 22/208 (10%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEE--EEYLGKEEYLKE 82
+ L + EVE E+ + E E E ++ L + E+ EE ++ L +E+ +
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 83 EEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGK 142
E+ L +E EEEE LE+ E EE E+E L +EE + E +
Sbjct: 656 EQRLKRE---EEEERLEQRLKREHEEERREQE-------------LAEEEQEQARERIKS 699
Query: 143 EGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLE-EEKALEKEENL---EEEEALEKEE 198
+ E D K Y + G++ E EEK +E L EEE A +++
Sbjct: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ 759
Query: 199 NLDGKENLYKKYLKEPKASYSSQTMLLR 226
+ + + ++ E K+ Q + R
Sbjct: 760 EEEQRRDFTWQWQAEEKSERGRQRLSAR 787
Score = 41.6 bits (96), Expect = 0.003
Identities = 47/192 (24%), Positives = 88/192 (45%), Gaps = 15/192 (7%)
Query: 27 LPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYL--GKEEYLKEEE 84
L E++ EL E ++E E E + + + LEEE+ +E+ L+ +E
Sbjct: 1710 LQEEQQLRRQEL-ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE 1768
Query: 85 ---YLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLG 141
+EE L +E ++ E + EEE L +E EE+ L ++ + +Y
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE---REEQQLRPQQ--RDGKYRW 1823
Query: 142 KEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLD 201
+E L+ E+ + + + Y EE++ ++ EE+ L +EE E++ E+E L
Sbjct: 1824 EEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEE--EQKRRQERERKL- 1880
Query: 202 GKENLYKKYLKE 213
+E ++ KE
Sbjct: 1881 -REEHIRRQQKE 1891
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/219 (24%), Positives = 91/219 (41%), Gaps = 42/219 (19%)
Query: 38 LDEESLQ----DESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLE 93
LDEE ES + + + + + LEEE + + +E+E E E
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQE----RELAE 150
Query: 94 EEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIE 153
EE EK LE+ + +E L ++ +E+ +EE EEE L E E++ +
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQ----RQEWQEREERRAEEEQLQSCKGHETEEFPD 206
Query: 154 EVDYLGKKAYL-------------------------EEEEYLGKKSYL-EEEKALEKEEN 187
E + L ++ L EE+E+ +++ L +EE+ L++EE
Sbjct: 207 E-EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 188 LEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLR 226
+ E E+EE L L ++ L+ + Q LR
Sbjct: 266 QRQRELQEEEEQL---RKLERQELRRERQEEEQQQQRLR 301
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 67.4 bits (163), Expect = 4e-11
Identities = 65/182 (35%), Positives = 92/182 (50%), Gaps = 33/182 (18%)
Query: 28 PSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLG 87
P EK ++V+ ++ E FS E ESL D+ LE++E L EE +EE
Sbjct: 2209 PKEKFSSQVD----EVESEEHFSEEMESLLDE--LEKQESLSSEEEEEREE--------- 2253
Query: 88 KEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLE 147
EE EEEE E EEEE EEEE G+E +E+EE EE ++++ KE E
Sbjct: 2254 -EEEREEEEVRE-----EEEERKEEEE--GEEKQVEKEE----EEKKKKKKEKKKEEVQE 2301
Query: 148 KEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLE-EEEALEKEENLDGKENL 206
KE+ EE K+ + EEE EEE++ EE ++ E+E L+KE+ +E
Sbjct: 2302 KEEVFEE-----KEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQR 2356
Query: 207 YK 208
K
Sbjct: 2357 RK 2358
Score = 60.8 bits (146), Expect = 4e-09
Identities = 65/208 (31%), Positives = 96/208 (46%), Gaps = 49/208 (23%)
Query: 36 VELDEESLQDESPFSPEGES--LEDKEYLEEEEDLEEEEYLG------------------ 75
+ +E+ ++ES + + L+D EEE +EEEE +
Sbjct: 2154 INKEEKMTEEESKLARKHSEVILDD----EEEGGIEEEEVIPFLKRRWRKRKEAKRGDKP 2209
Query: 76 KEEYLKEEEYLGKEEHLEEE-----EYLEKAGYL--EEEEYIEEEEYLGKEGYLEEEEYL 128
KE++ + + + EEH EE + LEK L EEEE EEEE +E EEEE
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE-- 2267
Query: 129 GKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL 188
E EEEE G+E +EKE E + KK ++EE K+ EE++ + EE
Sbjct: 2268 ---ERKEEEE--GEEKQVEKE----EEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEET 2318
Query: 189 -------EEEEALEKEENLDGKENLYKK 209
EEEE+ EE +D ++ + KK
Sbjct: 2319 ESLSDEEEEEESCSLEEEVDREKEILKK 2346
Score = 54.3 bits (129), Expect = 4e-07
Identities = 80/352 (22%), Positives = 155/352 (44%), Gaps = 47/352 (13%)
Query: 22 YSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLK 81
+ + L E E+ E +++E S ++E EG+ +E+K+ L EEE+ + +E+ +
Sbjct: 1709 WQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQ---REKLSE 1765
Query: 82 EEEYLGKEEHL--EEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEY 139
EE L +EE L +E+E L + +E+ EEEE LG++ +E+ +E++
Sbjct: 1766 EETKLAQEEELLIQEKEKLAQ----HKEKMPEEEERLGRK----------REQLIEKKMK 1811
Query: 140 LGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEEN 199
L + ++E +I ++ L K + + KK+ +E+K L +E +E+ A KE
Sbjct: 1812 LAQ----KRERWINSMEELTKNKMILYQ----KKNLAQEKKNLAQE---KEKLAQRKENL 1860
Query: 200 LDGKENL--YKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSES 257
L KE L KK L + K +L +QV LT T E
Sbjct: 1861 LYNKERLTHSKKQLVQVKNKLGMFNKIL----------AQVEEKLTQEK--ETVIKKKEK 1908
Query: 258 ATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKL---APEEHVNTKVQ 314
E+ + L+ + Q ++ + K+ + ++ +L E+ +N +++
Sbjct: 1909 LAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMK 1968
Query: 315 QKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFKTIIKE 366
+ EE + KE G T E+ + ++ +++ K ++ E
Sbjct: 1969 RLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHE 2020
Score = 53.5 bits (127), Expect = 6e-07
Identities = 44/146 (30%), Positives = 70/146 (47%), Gaps = 10/146 (6%)
Query: 74 LGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIE------EEEYLGKEGYLEEEEY 127
+ KEE + EEE +H E E+ G +EEEE I + K G +E++
Sbjct: 2154 INKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKF 2213
Query: 128 LGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEEN 187
+ + +E EE+ +E E ++E++ + EEEE ++ EEE E+EE
Sbjct: 2214 SSQVDEVESEEHFSEE----MESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269
Query: 188 LEEEEALEKEENLDGKENLYKKYLKE 213
EEEE EK+ + +E KK K+
Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Score = 51.6 bits (122), Expect = 2e-06
Identities = 52/187 (27%), Positives = 85/187 (45%), Gaps = 23/187 (12%)
Query: 46 ESPFSPEGESLEDKE--YLEEEEDL--EEEEYLGKEEYL--KEEEYLGKEEHLEEEEYLE 99
E S E L+ KE + E+ +L +E++ K+ L K + KEE + EEE
Sbjct: 2108 ERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEE--S 2165
Query: 100 KAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLG 159
K E +++EE EG +EEEE + + + K G KE + +VD +
Sbjct: 2166 KLARKHSEVILDDEE----EGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVE 2221
Query: 160 KKAY-----------LEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYK 208
+ + LE++E L + E E+ E+EE EE E++E +G+E +
Sbjct: 2222 SEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVE 2281
Query: 209 KYLKEPK 215
K +E K
Sbjct: 2282 KEEEEKK 2288
Score = 51.2 bits (121), Expect = 3e-06
Identities = 38/128 (29%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Query: 21 QYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYL 80
Q S + E+ + E E +EE +++E E E E+K+ +EEE+ ++++ K+E +
Sbjct: 2240 QESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEV 2299
Query: 81 --KEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEE 138
KEE + KEE + EEE + EEEE EE + +E + ++E K + +
Sbjct: 2300 QEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKS 2359
Query: 139 YLGKEGYL 146
G+E L
Sbjct: 2360 LRGRERVL 2367
Score = 50.4 bits (119), Expect = 5e-06
Identities = 88/462 (19%), Positives = 179/462 (38%), Gaps = 59/462 (12%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEE 84
+N+ S K + DEE + E S EGE ++++ EE+ ++EE K + +
Sbjct: 1526 ENMLSSKSKEQQYKDEEEVTLEEEVSREGEE-KEQQVTEEQRHIQEEH---KWARIHRKR 1581
Query: 85 YLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEG 144
+++ +EE L + EEE+ +EE L +E + Y+ + ++ E EG
Sbjct: 1582 ARAEKKRAQEERKLAQ----EEEKLAQEERQLAQEERKLAQAYVKITQ--DDREMAQAEG 1635
Query: 145 -YLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYL---------EEEKALEKEENLEE---- 190
+ +KE+ + + G+K E E+ K+ L EEEK +K L E
Sbjct: 1636 KFAQKEETLAQ---RGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNI 1692
Query: 191 -----EEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVP 245
EE ++E+NLD +E + L+E + + + +
Sbjct: 1693 LAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEG------------ 1740
Query: 246 LTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAP 305
V E + E ++R + S+ + + ++ K + Q
Sbjct: 1741 ------KLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEE 1794
Query: 306 EEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFKTIIK 365
EE + K +Q E+ ++ A K W +E + +N K + +
Sbjct: 1795 EERLGRKREQLIEKK-MKLAQKRERWINSMEELTKNKMILYQKKNLAQEK-----KNLAQ 1848
Query: 366 EMAAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYEKFKETILRIKRRREAQKLTEMTS 425
E + +E+ +L S+ K ++ +K F + + +++ + +K T +
Sbjct: 1849 EKEKLAQRKENLLYNKERLTHSK---KQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKK 1905
Query: 426 FTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLERDKEWIQKK 467
++ + E +K +++ + KL +K +Q K
Sbjct: 1906 KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGK 1947
Score = 47.4 bits (111), Expect = 5e-05
Identities = 87/420 (20%), Positives = 167/420 (39%), Gaps = 76/420 (18%)
Query: 58 DKEYLEEEEDLE--------EEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEY 109
+K L+EEE L EEE L +++ LK EE+ E++ + E+ Y +EEE
Sbjct: 1486 EKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQ-YKDEEEV 1544
Query: 110 IEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEY 169
EEE + +EG +E++ ++ H++EE K A +
Sbjct: 1545 TLEEE-VSREGEEKEQQVTEEQRHIQEEH---------------------KWARIHR--- 1579
Query: 170 LGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDAR 229
K++ E+++A E+ + +EEE L +EE ++ +E + + + +D R
Sbjct: 1580 --KRARAEKKRAQEERKLAQEEEKLAQEE---------RQLAQEERKLAQAYVKITQDDR 1628
Query: 230 SPDAGPSQVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSL 289
++++ + ++ TL +R + + K L
Sbjct: 1629 E-----------------------MAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKL 1665
Query: 290 KSKSETEQETTTKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDE 349
K E KLA + +V+ + V E +E D E +LE + D
Sbjct: 1666 AKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDM 1725
Query: 350 NFLNSSYQTVFK---TIIKEMAAHNELEEDFDIPLTKLLESENRW----KLVIMLKKNYE 402
L+ + + + +++E E EE KL E E + +L+I K+
Sbjct: 1726 EELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLA 1785
Query: 403 KFKETILRIKRRREAQKLTEMTSFTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLERDKE 462
+ KE + + R +K ++ L K EE+ K + +++ +K L ++K+
Sbjct: 1786 QHKEKMPE-EEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKK 1844
Score = 43.1 bits (100), Expect = 9e-04
Identities = 88/333 (26%), Positives = 147/333 (44%), Gaps = 43/333 (12%)
Query: 29 SEKEDTEVELDEESLQDESPFSPEGESLEDK--EYLEEEEDL--------EEEEYLGK-- 76
++KE+T + E+ Q+ + + + L K + EEE L E + L +
Sbjct: 1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKV 1697
Query: 77 EEYLKEEEYLGKEE-----HLEEEEY-LEKAGYLEEEEYIEEEEYL-GKEGYLEEEEYLG 129
EE + E+ L +E LEE E+ +E+ + EEE EE + + K+ EEEE L
Sbjct: 1698 EELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALA 1757
Query: 130 --KEEHLEEEEYLGKEGYLEKEDYIEEVDYLG--KKAYLEEEEYLGKKSYLEEEKALEKE 185
+E+ EEE L + E+E I+E + L K+ EEEE LG+K EK ++
Sbjct: 1758 WQREKLSEEETKLAQ----EEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLA 1813
Query: 186 ENLEE-----EEALEKEENLDGKENL--YKKYL--KEPKASYSSQTMLLRDARSPDAGPS 236
+ E EE + + L K+NL KK L ++ K + + +L R +
Sbjct: 1814 QKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQ 1873
Query: 237 QVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETE 296
V + + + V E T+ E ++ ++ + ++T+ + SL K E
Sbjct: 1874 LVQVKNKLGMFNKILAQVEEKLTQEKETVIK--KKEKLAETEKKLVQVE-DSLAKKQEKL 1930
Query: 297 QETTTKLAPEEHVNTKVQQKKE-ENVLEFASKE 328
+ KLA E+ VQ KK L+ A +E
Sbjct: 1931 AQEKMKLALEK---AMVQGKKRLRGELDIAKEE 1960
Score = 40.0 bits (92), Expect = 0.007
Identities = 107/449 (23%), Positives = 182/449 (40%), Gaps = 45/449 (10%)
Query: 59 KEYLEEEEDLEEE-EYLG--KEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEY 115
+E +EE D+ EE E + +E+ +K+E L E + +KA +E + + E
Sbjct: 1418 REMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAW--DEWKQVHGETR 1475
Query: 116 LGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEE-----EEYL 170
+ + EE E + L+EEE L + G EK EE+ KK EE E L
Sbjct: 1476 KSWKAWKEEWE----KRLLQEEEKLHQAG--EKLSPEEEMLQEDKKLKWEEWKQVWENML 1529
Query: 171 GKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARS 230
KS ++ K E+E LEEE + E EE KE + + + + + + AR+
Sbjct: 1530 SSKSKEQQYKD-EEEVTLEEEVSREGEE----KEQQVTEEQRHIQEEHKWARIHRKRARA 1584
Query: 231 PDAGPSQVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQ----ASQTDWCYDRTAV 286
+ A + A E +L + +Q +Q + + +
Sbjct: 1585 EKKRAQEERKLAQEEEKLAQEE--RQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKE- 1641
Query: 287 KSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVED 346
++L + E + KLA + K +K + A K + ++I +VE+
Sbjct: 1642 ETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEV--KNILAQKVEE 1699
Query: 347 LDENFLNSSYQTVFKTIIKEMAAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYEKFKE 406
L + N +Q K + +E+ ELE D + K E ++ KK + +E
Sbjct: 1700 LPQREQNLDWQE--KELAQEL---EELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754
Query: 407 TIL--RIKRRREAQKLTEMTSFTFHLMSKPTPEK---PETEEI--QKPQRVVHHRKKLER 459
+ R K E KL + K K PE EE +K ++++ + KL +
Sbjct: 1755 ALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQ 1814
Query: 460 DKE-WIQKKTVVHQGDGKLILYPNKNVYQ 487
+E WI + + K+ILY KN+ Q
Sbjct: 1815 KRERWINSMEELTK--NKMILYQKKNLAQ 1841
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 67.4 bits (163), Expect = 4e-11
Identities = 83/310 (26%), Positives = 130/310 (41%), Gaps = 29/310 (9%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKE 89
E E +E+E ++ +E S + E E E EEE + EEEE K+ +K KE
Sbjct: 463 EDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE 522
Query: 90 EHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKE 149
E E+EE EE + EEEE G + EE KE E+EE +EG E E
Sbjct: 523 EEGEKEE--------EEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAE 574
Query: 150 DYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYKK 209
EE + +K E+ E + K L + +EK E + E GK + K
Sbjct: 575 AEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE-KGKSPVPKS 633
Query: 210 YLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSELLLTLY 269
++E S ++ + +SP P+ SPVS+S E
Sbjct: 634 PVEEKGKSPVPKSPVEEKGKSP---------VPKSPVEEKGKSPVSKSPVEEK------- 677
Query: 270 RRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLEFASKEN 329
+S ++ ++ + K + + E+E K AP+E KV +KKEE + K+
Sbjct: 678 AKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEE---KV-EKKEEKPKDVPEKKK 733
Query: 330 FWDGITDESI 339
+ +E++
Sbjct: 734 AESPVKEEAV 743
Score = 44.7 bits (104), Expect = 3e-04
Identities = 83/410 (20%), Positives = 162/410 (39%), Gaps = 36/410 (8%)
Query: 3 AENNQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEG----ESLED 58
AE +++ P T P+ + E+E+ + E +EE +S + EG E +
Sbjct: 501 AEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE 560
Query: 59 KEYLEEEEDLEEEEYLGKEEYLKEEEYL-GKEEHLEEEEYLEKAGYLEEEEYIEEEEYLG 117
KE E+EE E E G+E KEE+ + K E + +E L +E+ E + + +
Sbjct: 561 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE--KAKSPVP 618
Query: 118 KEGYLEEEEYLGKEEHLEEE----------EYLGKEGYLEKEDYIEEVDYLGKKAYLEEE 167
K E+ + + +EE+ E GK + + + K E+
Sbjct: 619 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 678
Query: 168 EYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRD 227
+ KS +EE K+ + E++E EKE KE +K ++PK + +
Sbjct: 679 KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKD--------VPE 730
Query: 228 ARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVK 287
+ ++ + V +T + + + E + L + +A + + K
Sbjct: 731 KKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK 790
Query: 288 SLKSKSETEQETTTKLAPEEHVNTKVQQK---KEE------NVLEFASKENFWDGITDES 338
K + + ++ +E V + ++K +EE N L+ + + G D+S
Sbjct: 791 GAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGG--DKS 848
Query: 339 IDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDFDIPLTKLLESE 388
+K+ V E + K I K + ++EE + KL+ ++
Sbjct: 849 EEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTK 898
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 67.4 bits (163), Expect = 4e-11
Identities = 83/310 (26%), Positives = 130/310 (41%), Gaps = 29/310 (9%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKE 89
E E +E+E ++ +E S + E E E EEE + EEEE K+ +K KE
Sbjct: 87 EDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE 146
Query: 90 EHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKE 149
E E+EE EE + EEEE G + EE KE E+EE +EG E E
Sbjct: 147 EEGEKEE--------EEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAE 198
Query: 150 DYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYKK 209
EE + +K E+ E + K L + +EK E + E GK + K
Sbjct: 199 AEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE-KGKSPVPKS 257
Query: 210 YLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSELLLTLY 269
++E S ++ + +SP P+ SPVS+S E
Sbjct: 258 PVEEKGKSPVPKSPVEEKGKSP---------VPKSPVEEKGKSPVSKSPVEEK------- 301
Query: 270 RRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLEFASKEN 329
+S ++ ++ + K + + E+E K AP+E KV +KKEE + K+
Sbjct: 302 AKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEE---KV-EKKEEKPKDVPEKKK 357
Query: 330 FWDGITDESI 339
+ +E++
Sbjct: 358 AESPVKEEAV 367
Score = 44.7 bits (104), Expect = 3e-04
Identities = 83/410 (20%), Positives = 162/410 (39%), Gaps = 36/410 (8%)
Query: 3 AENNQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEG----ESLED 58
AE +++ P T P+ + E+E+ + E +EE +S + EG E +
Sbjct: 125 AEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE 184
Query: 59 KEYLEEEEDLEEEEYLGKEEYLKEEEYL-GKEEHLEEEEYLEKAGYLEEEEYIEEEEYLG 117
KE E+EE E E G+E KEE+ + K E + +E L +E+ E + + +
Sbjct: 185 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE--KAKSPVP 242
Query: 118 KEGYLEEEEYLGKEEHLEEE----------EYLGKEGYLEKEDYIEEVDYLGKKAYLEEE 167
K E+ + + +EE+ E GK + + + K E+
Sbjct: 243 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 302
Query: 168 EYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRD 227
+ KS +EE K+ + E++E EKE KE +K ++PK + +
Sbjct: 303 KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKD--------VPE 354
Query: 228 ARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVK 287
+ ++ + V +T + + + E + L + +A + + K
Sbjct: 355 KKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK 414
Query: 288 SLKSKSETEQETTTKLAPEEHVNTKVQQK---KEE------NVLEFASKENFWDGITDES 338
K + + ++ +E V + ++K +EE N L+ + + G D+S
Sbjct: 415 GAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGG--DKS 472
Query: 339 IDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDFDIPLTKLLESE 388
+K+ V E + K I K + ++EE + KL+ ++
Sbjct: 473 EEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTK 522
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 66.6 bits (161), Expect = 7e-11
Identities = 54/179 (30%), Positives = 98/179 (54%), Gaps = 15/179 (8%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKE 89
EKE+ EL EE + ++ + E +++E + E+E +E+E + + +EE+ +E
Sbjct: 388 EKEEKIREL-EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE---AKMWRQEEKIREQE 443
Query: 90 EHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEE--HLEEEEYLGKEGYLE 147
E + E+ EK + +EE+ E+E+ +E E+EE +EE H +EE + KE E
Sbjct: 444 EKIREQ---EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE 500
Query: 148 KEDYI---EEVDYLGKKAYLEEEEYL---GKKSYLEEEKALEKEENLEEEEALEKEENL 200
+E+ I EE + ++ E+EE + +K + +EEK E+EE EEE + ++E +
Sbjct: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559
Score = 65.9 bits (159), Expect = 1e-10
Identities = 68/314 (21%), Positives = 151/314 (48%), Gaps = 25/314 (7%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEE---YLKEEEYLG 87
+E+ E +E+ + E + E + ++E + EEE +E+E + ++E + +EE +
Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ 494
Query: 88 KEEHLEEEEYL---EKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEG 144
KE+ E+EE + E+ + +EE+ E+EE + + +EE+ +EE + E+E + +E
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE----QEEKMWRQEEKIREQEEMWRE- 549
Query: 145 YLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL--EEEEALEKEE-NLD 201
E+ + E + + ++ +E+E K + +EEK E+EE + +EE+ E+EE +
Sbjct: 550 ----EEKMHEQEKIWEEEKRQEQE---DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQE 602
Query: 202 GKENLYK--KYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESAT 259
+E ++K + ++E + Q +R+ ++T + + E
Sbjct: 603 QEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG-EQEEKMCEQEE 661
Query: 260 ESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEE 319
+ E T++R+ + + R + ++ + E QE K+ +E + ++K +E
Sbjct: 662 KMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721
Query: 320 NVLEF-ASKENFWD 332
+ +E W+
Sbjct: 722 QEEKMRRQEEKMWE 735
Score = 62.4 bits (150), Expect = 1e-09
Identities = 60/210 (28%), Positives = 113/210 (53%), Gaps = 22/210 (10%)
Query: 31 KEDTEVELDEESLQDESPFSPEG--ESLEDKEYLEEEEDLEEEEYLGK-EEYLKEEEYLG 87
+E E+ +EE + ++ E + EDK + +EE+ E+EE + + EE ++E+E
Sbjct: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE--E 598
Query: 88 KEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHL--EEEEYLG--KE 143
K + EE+ + ++ E+EE I+E+E E E+EE + ++E + E+EE +G +E
Sbjct: 599 KRQEQEEKMWKQEEKIREQEEKIQEQE----EKIREQEEKIREQEEMTQEQEEKMGEQEE 654
Query: 144 GYLEKEDYIEEVD--YLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEE--ALEKEEN 199
E+E+ ++E + ++ + E+E KK +EEK E+EE ++E+E E+EE
Sbjct: 655 KMCEQEEKMQEQEETMWRQEEKIREQE---KKIREQEEKIREQEEMMQEQEEKMWEQEEK 711
Query: 200 LDGKENLYKKYLKEPKASYSSQTMLLRDAR 229
+ +E K +E K + M ++ R
Sbjct: 712 MCEQEE--KMQEQEEKMRRQEEKMWEQEVR 739
Score = 57.4 bits (137), Expect = 4e-08
Identities = 51/201 (25%), Positives = 108/201 (53%), Gaps = 24/201 (11%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDL-EEEEYLGKEEYLKEEEYLGK 88
E+E+ E +E+ + E + E ++E + E+E + EEE+ +E+ + +E +
Sbjct: 521 EQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580
Query: 89 EEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEK 148
E+ EE+ + ++ E+EE +E+E ++ + +EE+ +EE ++E+E E E+
Sbjct: 581 EQ--EEKVWRQEEKIREQEEKRQEQE---EKMWKQEEKIREQEEKIQEQE----EKIREQ 631
Query: 149 EDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEAL--EKEENLDGKENL 206
E+ I E + + + E+EE +G+ +EEK E+EE ++E+E +EE + +E
Sbjct: 632 EEKIREQEEMTQ----EQEEKMGE----QEEKMCEQEEKMQEQEETMWRQEEKIREQE-- 681
Query: 207 YKKYLKEPKASYSSQTMLLRD 227
K ++E + Q ++++
Sbjct: 682 --KKIREQEEKIREQEEMMQE 700
Score = 57.0 bits (136), Expect = 6e-08
Identities = 52/190 (27%), Positives = 104/190 (54%), Gaps = 23/190 (12%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESL---EDKEYLEEEEDLEEEEYLGKEEYL---KEE 83
E+E+ E +E+ + E + E + E+K +EE E+EE + ++E + KEE
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 377
Query: 84 EYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEE---YL 140
+ +EE + E+E EK LEE+ + E+E+ +E +EEE + ++E +E+E +
Sbjct: 378 KMRRQEEMMWEKE--EKIRELEEKMH-EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 434
Query: 141 GKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEAL-EKEEN 199
+E E+E+ I E + KK + +EE+ + E++ + +EE +E+E + +EE
Sbjct: 435 QEEKIREQEEKIREQE---KKMWRQEEK-------IHEQEKIREEEKRQEQEEMWRQEEK 484
Query: 200 LDGKENLYKK 209
+ +E ++++
Sbjct: 485 IHEQEEIWRQ 494
Score = 47.4 bits (111), Expect = 5e-05
Identities = 59/223 (26%), Positives = 112/223 (50%), Gaps = 32/223 (14%)
Query: 21 QYSTQNLPSEKEDTEVELDEESLQDESP-FSPEGESLEDKEYLEEEED--------LEEE 71
Q + + L + E ++ L ++ LQ E+ E +S+ K + EE+ +EE
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
Query: 72 EYLGKEEYLK--EEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYL------- 122
+ +EE ++ EE+ +EE + E+E EK EE+ +EE KE +
Sbjct: 301 KMWRQEEKIQEWEEKIQEQEEKIREQE--EKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 123 -EEEEYLGKEEHL--EEEEYLGKEGYL--EKEDYIEEVD---YLGKKAYLEEEEYLGKKS 174
E+EE + ++E + E+EE + ++ + EKE+ I E++ + +K +EE+ ++
Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 418
Query: 175 YLEEEKALEKEENL--EEEEALEKEENLDGKENLYKKYLKEPK 215
E+EK E+E + +EE+ E+EE + +E K + +E K
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEKI--REQEKKMWRQEEK 459
Score = 47.0 bits (110), Expect = 6e-05
Identities = 88/461 (19%), Positives = 186/461 (40%), Gaps = 52/461 (11%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEE----DLEEEEYLGKEEYL 80
+ L E++ +EL ++ DE + L++K L E E L +E K E
Sbjct: 196 EELTKERDALSLELYRNTITDEE-LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 254
Query: 81 K----EEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEE 136
K +++ + +HL +E A + + +EE E + +EE+ +EE ++E
Sbjct: 255 KLLLPQQQLQAEADHLGKELQSVSA---KLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 137 EEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEAL-- 194
E E E+E+ I E + + E+EE + + +EE EKEE + +E +
Sbjct: 312 WE----EKIQEQEEKIREQE----EKIREQEEKMRR----QEEMMWEKEEKMRRQEEMMW 359
Query: 195 EKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPV 254
EKEE + +E + + KE K + M ++ + + L +
Sbjct: 360 EKEEKMRRQEEM--MWEKEEKMRRQEEMMWEKEEKIRE---------LEEKMHEQEKIRE 408
Query: 255 SESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQ 314
E + E + +R + W R K + + + ++ EE ++ + +
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMW---RQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465
Query: 315 QKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNELE 374
++EE E +E W +E I + E + ++ + + K K ++
Sbjct: 466 IREEEKRQE---QEEMWR--QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIR 520
Query: 375 EDFDIPLTKLLESENR-WKLVIMLKKNYEKFKETILRIKRRR--EAQKLTEMTSFTFHLM 431
E + K+ E E + W+ +++ E ++E ++ + E +K E +
Sbjct: 521 EQEE----KIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 432 SKPTPEKPETEEIQKPQRVVHHRKKLERDKEWIQKKTVVHQ 472
K ++ + ++ R +++ + +K W Q++ + Q
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/174 (25%), Positives = 86/174 (49%), Gaps = 40/174 (22%)
Query: 31 KEDTEVELDEESLQD-ESPFSPEGESLEDKEYLEEEEDL----EEEEYLGKEEYLKEEE- 84
K++ ++ EE +Q+ E + E + ++E + +E++ +EE+ +EE ++E+E
Sbjct: 609 KQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668
Query: 85 -YLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKE 143
+EE + E+E + E+EE I E+E + +E +EE+ +EE + E+E
Sbjct: 669 TMWRQEEKIREQEKKIR----EQEEKIREQEEMMQE---QEEKMWEQEEKMCEQE----- 716
Query: 144 GYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKE 197
EK ++E+E +K +EEK E+E L ++E +E
Sbjct: 717 ---EK---------------MQEQE---EKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 38.5 bits (88), Expect = 0.021
Identities = 28/113 (24%), Positives = 66/113 (58%), Gaps = 9/113 (7%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKE---YLEEEEDLEEEEYLGK-EEYLKEEEY 85
E+E+ E +E+ + E + E ++++E + +EE+ E+E+ + + EE ++E+E
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 86 LGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEE 138
+ +E+ EE+ + ++ E+EE ++E+E ++ +EE+ +E L ++E
Sbjct: 697 MMQEQ--EEKMWEQEEKMCEQEEKMQEQE---EKMRRQEEKMWEQEVRLRQQE 744
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 66.6 bits (161), Expect = 7e-11
Identities = 82/451 (18%), Positives = 192/451 (42%), Gaps = 61/451 (13%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDL--EEEEYLGKEEYLKEEEYLGK 88
++D + EE ++++ + E + +++ ++E+E ++EE + +EE ++E E +
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMR 460
Query: 89 EEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEK 148
EE E EK EE + +EE+ ++ E++E L ++E ++E+E E E+
Sbjct: 461 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE----EKIWEQ 516
Query: 149 EDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL-EEEEALEKEEN--LDGKEN 205
E+ I + +EE + +K +EK E+E+ + E+EE + +E D +E
Sbjct: 517 EEKIRD----------QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566
Query: 206 LYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSELL 265
+ KK ++ K ++ + + + R + + E E++
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMRER---------------------EKKMREEEEMM 605
Query: 266 LTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLEFA 325
+ Q + + + + + E QE K+ +E + ++K E
Sbjct: 606 REQEEKMQEQEEKM---QEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662
Query: 326 SKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDFDIPLTKLL 385
KE W+ + +K++ ++ + +++ E + ++ +D K+
Sbjct: 663 QKEKLWEHEKMQEQEKMQEQE----------EKIWEQEKMEKKTQEQEKKTWD--QEKMR 710
Query: 386 ESENRWKLVIMLKKNYEKFKETILRIKRRREAQKLTEMTSFTFHLMSKPTPEKPETEEIQ 445
E E+ + +++ E +E K + + +K+ E + K ++ + E Q
Sbjct: 711 EEESMREREKKMREEEEMMREQ--EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768
Query: 446 K----PQRVVHHRKKLERDKEWIQKKTVVHQ 472
+ +++ H K E++K W Q++ + Q
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQ 799
Score = 65.1 bits (157), Expect = 2e-10
Identities = 50/191 (26%), Positives = 96/191 (50%), Gaps = 11/191 (5%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKE 89
E+ED E +E+ E + E +E K +E++ ++EE + +EE ++E E +E
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 90 EHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEE---YLGKEEHLEEEEYL------ 140
E E EK EE+ +EE+ +E ++E+E + +E+ E+EE +
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 141 --GKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEE 198
KE E E E+ ++ + E+E + KK+ +E+K ++E+ EEE E+E+
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK 720
Query: 199 NLDGKENLYKK 209
+ +E + ++
Sbjct: 721 KMREEEEMMRE 731
Score = 63.2 bits (152), Expect = 8e-10
Identities = 59/196 (30%), Positives = 109/196 (55%), Gaps = 18/196 (9%)
Query: 24 TQNLPSEKEDTEVELDEESLQDESPFSPEGESL--EDKEYLEEEEDL---EEEEYLGKEE 78
TQ + D E +EES+++ E E + E +E ++E+E+ +EEE +EE
Sbjct: 696 TQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755
Query: 79 YL-KEEEYLGKEEHL-EEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHL-- 134
+ ++EE + +++ L E++E L + ++E+E I E+E ++ +EE+ G+EE +
Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRD---QEEKMRGQEEKMRG 812
Query: 135 EEEEYLGKE----GYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL-- 188
+EE+ G+E G EK EE + ++ +EE + +K +EEK E+EE +
Sbjct: 813 QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRG 872
Query: 189 EEEEALEKEENLDGKE 204
+EE+ E+EE + G+E
Sbjct: 873 QEEKMREQEEKMRGQE 888
Score = 61.2 bits (147), Expect = 3e-09
Identities = 50/180 (27%), Positives = 98/180 (54%), Gaps = 5/180 (2%)
Query: 30 EKEDTEVELDEESL-QDESPFSPEGESLEDKEYLEEEEDL-EEEEYLGKEEYLKEEEYLG 87
E+E+ E +E+ Q+E + E + E +E + E++ L E++E L + E ++E+E +
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ 680
Query: 88 K-EEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYL 146
+ EE + E+E +EK +E++ ++E+ +E E E+ + +EE + E+ +
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 147 EKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEE--EKALEKEENLEEEEALEKEENLDGKE 204
EK EE + ++ E+EE + ++ L E EK E E+ E+E+ E+EE + +E
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQE 800
Score = 60.8 bits (146), Expect = 4e-09
Identities = 58/236 (24%), Positives = 119/236 (50%), Gaps = 21/236 (8%)
Query: 22 YSTQNLPSEKE---DTEVELDEESLQDESPFSPEGESLE------DKEYLEEEEDLEEEE 72
+ Q LP +KE + E ++E +Q++ E E +E +K+ ++E+ EEE
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 73 YLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYI------EEEEYLGKEGYL-EEE 125
+E+ ++EEE + +E+ + +E EK EEE + E+EE + ++ L E++
Sbjct: 715 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Query: 126 EYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLG--KKSYLEEEKALE 183
E L + E ++E+E + ++ + D E++ +K +EE+ G +K + +EEK
Sbjct: 775 EKLWEHEKMQEQEKIWEQEE-KMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWG 833
Query: 184 KEENL--EEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQ 237
+EE + +EE+ +EE ++ K ++ ++E + Q +R+ G +
Sbjct: 834 QEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 60.1 bits (144), Expect = 7e-09
Identities = 49/191 (25%), Positives = 100/191 (52%), Gaps = 5/191 (2%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYL-EEEEDLEEEEYLGKEEYLKEEEYLGK 88
E+E + +E+ ++E E + E++E + E+EE ++E+E +E+ K E K
Sbjct: 573 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEK 632
Query: 89 EEHLEEEEYLEKAGYLEEEEYIEEEEYLG--KEGYLEEEEYLGKEEHLEEEEYLGKEGYL 146
+ EE+ + ++ E+EE + E++ L KE E E+ +E+ E+EE + ++ +
Sbjct: 633 MQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM 692
Query: 147 EKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKAL--EKEENLEEEEALEKEENLDGKE 204
EK+ +E ++ EEE ++ + EE+ + E+EE ++E+E +E+ + E
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE 752
Query: 205 NLYKKYLKEPK 215
K + +E K
Sbjct: 753 QEEKMWEQEEK 763
Score = 59.7 bits (143), Expect = 9e-09
Identities = 100/479 (20%), Positives = 203/479 (42%), Gaps = 68/479 (14%)
Query: 20 PQYSTQNLPSEKEDTEVELDEESL-----------QDESPFSPEGESLEDKEYL--EEEE 66
PQ T L E E EL E+ Q+E EG+ E +E + +E+
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR 322
Query: 67 DLEEEEYLGKEE-YLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGK--EGYLE 123
E+E+ L ++E L+E++ L ++E +E+ E+ + +EE+ E+EE + + E E
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQ--EEKMWEQEEKMREQEEKMWRQEERLWE 380
Query: 124 EEEYLGKEEH----LEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEE 179
+E+ + ++E EE + E EKE+ + E + + ++ EE KK +E+
Sbjct: 381 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE---KKMQEQEK 437
Query: 180 KALEKEENLEEEEAL-EKEENLDGKENLYKKYLKEPKASYSSQTMLLRDAR--SPDAGPS 236
K ++EE ++EEE + E+E+ + +E ++ +E K + M ++ + P
Sbjct: 438 KTRDQEEKMQEEERIREREKKMREEEETMRE--QEEKMQKQEENMWEQEEKEWQQQRLPE 495
Query: 237 QVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETE 296
Q E E E + + + + W ++ + K + + +
Sbjct: 496 QKEKLWE-----------QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 544
Query: 297 Q--ETTTKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNS 354
Q E K+ +E +++ E+ E ++ WD +K+ E+
Sbjct: 545 QMWEQEEKMRDQEQKMWDQEERMEKKTQE--QEKKTWD-----QEEKMREEE-------- 589
Query: 355 SYQTVFKTIIKEMAAHNELEEDFDIPLTKLLESENR-WKLVIMLKKNYEKFKETILRI-- 411
+ K + +E E EE K+ E E + W+ +++ EK E ++
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE 649
Query: 412 --KRRREAQKLTEMTSFTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLERDKEWIQKKT 468
++ E Q+L E + + E E++Q+ + + ++K+E+ + +KKT
Sbjct: 650 QEEKMWEQQRLPEQKEKLWE-----HEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703
Score = 59.7 bits (143), Expect = 9e-09
Identities = 94/476 (19%), Positives = 197/476 (41%), Gaps = 70/476 (14%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKE---YLEEEEDLEEEEYLGKEE--------- 78
+++ E+ E+ L+++ + E ++++E + +EE+ E+EE + ++E
Sbjct: 325 EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384
Query: 79 ---------------YLKEEEYLGKEEHLEEEEYL-EKAGYLEEEEYIEEEEYLGK---E 119
+ ++E KEE + E+E + E+ + EE+ ++E+E + E
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444
Query: 120 GYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEE 179
EEE +E+ + EEE +E + + E + +K + ++ K+ E+E
Sbjct: 445 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 504
Query: 180 KALEKEENL-EEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQV 238
K E+EE + E+EE + +E + G+E KK ++ K M ++ + D Q
Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQE---KKMWRQEKMREQEDQMWEQEEKMRD----QE 557
Query: 239 TTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQE 298
+ E T E + R + + R + ++ + E QE
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM---REEEEMMREQEEKMQE 614
Query: 299 TTTKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQT 358
K+ +E + ++K +E +E W+ +E + + E + ++ L +
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQE------QEEKMWE--QEEKMWEQEEKMWEQQRLPEQKEK 666
Query: 359 VFKTIIKEMAAHNELEEDFDIPLTKLLESENR-WKLVIMLKKNYEKFKETILRIKRR--- 414
+++ H +++E K+ E E + W+ M KK E+ K+T + K R
Sbjct: 667 LWE--------HEKMQEQ-----EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Query: 415 --REAQKLTEMTSFTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLER-DKEWIQKK 467
RE +K + E+ E + Q+ + K E+ +K W Q++
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR 769
Score = 51.6 bits (122), Expect = 2e-06
Identities = 45/156 (28%), Positives = 83/156 (53%), Gaps = 15/156 (9%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYL---KEEEYL 86
E+E+ E +E+ + E + E KE L E E ++E+E + ++E +EE+
Sbjct: 745 EQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMR 804
Query: 87 GKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYL--EEEEYLGKEEHLEEEEYLGKEG 144
G+EE + +E EK EE+ + +EE+ G+E + +EE+ G+EE +EE+ +E
Sbjct: 805 GQEEKMRGQE--EKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEK 862
Query: 145 YLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEK 180
E+E+ + G++ + E+E +K +EEK
Sbjct: 863 MREQEEKMR-----GQEEKMREQE---EKMRGQEEK 890
Score = 32.3 bits (72), Expect = 1.5
Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 4/68 (5%)
Query: 44 QDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEE--YLGKEEHLEEEEYLEKA 101
Q+E + E + +E + +E+ EE+ G+EE ++E+E G+EE + E+E EK
Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQE--EKM 884
Query: 102 GYLEEEEY 109
EE+ Y
Sbjct: 885 RGQEEKIY 892
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 65.1 bits (157), Expect = 2e-10
Identities = 68/182 (37%), Positives = 89/182 (48%), Gaps = 17/182 (9%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEY----------- 79
+E+ E E +EE + E EGE E++ + EE+ EE E G+EE
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947
Query: 80 --LKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEE 137
+E E+ G+EE E E E G EE E EEE EG EE E G+EE EE
Sbjct: 948 GEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007
Query: 138 EYLGKEGYLEKEDYIE-EVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEK 196
E G EG E+E +E EV+ G++ E EE G++ E EK E EEN E E+
Sbjct: 1008 EGEG-EGEEEEEGEVEGEVE--GEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEE 1064
Query: 197 EE 198
EE
Sbjct: 1065 EE 1066
Score = 63.9 bits (154), Expect = 5e-10
Identities = 65/187 (34%), Positives = 91/187 (48%), Gaps = 13/187 (6%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLE---EEEDLEEEEYLGKEEYLKEEEYL 86
++E + E D+ + E P E E E +E+ + EE++ +E E ++E +E E
Sbjct: 671 DEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEG 730
Query: 87 GKEEH---------LEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEE 137
G+EEH EEEE E G E E E E +EG ++EE GKEE EEE
Sbjct: 731 GEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790
Query: 138 EYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL-EEEEALEK 196
G+ E E EE + G+ E EE G++ EEE E+EE EEEE +
Sbjct: 791 GDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGE 850
Query: 197 EENLDGK 203
EE +GK
Sbjct: 851 EEEGEGK 857
Score = 60.5 bits (145), Expect = 5e-09
Identities = 75/212 (35%), Positives = 97/212 (45%), Gaps = 28/212 (13%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLE----EEEYLGK-EEYLKEEE 84
E E+ E E +EE + E EGE E++ E EE+ E EEE GK EE +E E
Sbjct: 870 EGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGE 929
Query: 85 YLGKEEHLE----------EEEYLEKAGYLEEEEYIEEEEYLGK----EGYLEEEEYLGK 130
G+EE E EEE E G EE E EEE G+ EG EEEE G+
Sbjct: 930 GEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGE 989
Query: 131 EEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEE 190
E E EE +EG E+E G+ EEEE + EE E EE E
Sbjct: 990 GEEEEGEEEGEEEGEGEEE---------GEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040
Query: 191 EEALEKEENLDGKENLYKKYLKEPKASYSSQT 222
EE E+E+ +G+EN + +E + +T
Sbjct: 1041 EEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072
Score = 58.5 bits (140), Expect = 2e-08
Identities = 68/177 (38%), Positives = 86/177 (48%), Gaps = 14/177 (7%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKE 89
E+E E E +EE + E EGE E + EEE + E EE G+ E +E E G+E
Sbjct: 859 EEEGEEGEGEEEGEEGEG----EGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEE 914
Query: 90 EHLE---EEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEH-----LEEEEYLG 141
E E EEE E G EEEE E E EG EE E+ G+EE EE E G
Sbjct: 915 EEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG 974
Query: 142 KEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEE 198
+EG E E+ EE + G++ EEE + E E E+EE E E +E EE
Sbjct: 975 EEGEGEGEE--EEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029
Score = 56.6 bits (135), Expect = 8e-08
Identities = 71/193 (36%), Positives = 95/193 (49%), Gaps = 30/193 (15%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKE 89
E+E+ + E +EE + E EGE +E E +EE + ++EE GKEE +EE G+
Sbjct: 739 EEEEGDRE-EEEEKEGEGKEEGEGEEVEG-EREKEEGERKKEERAGKEEKGEEEGDQGEG 796
Query: 90 EHLEEE---EYLEKAGYLE----------EEEYIEEEEYLGKEGYLEEEEYLGKEEHLE- 135
E E E E E+ G +E EE EE E +EG EEEE G+EE E
Sbjct: 797 EEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEG 856
Query: 136 --EEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKE---ENLEE 190
EEE G+EG E E+ EE + G EEEE G+ E + E+E E EE
Sbjct: 857 KGEEE--GEEG--EGEEEGEEGEGEG-----EEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907
Query: 191 EEALEKEENLDGK 203
E +EE +GK
Sbjct: 908 GEGEGEEEEGEGK 920
Score = 55.5 bits (132), Expect = 2e-07
Identities = 70/178 (39%), Positives = 89/178 (50%), Gaps = 10/178 (5%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKE 89
E+E+ E E +EE + E EGE E++ + EE+ EE E G+EE +E E G+E
Sbjct: 827 EEEEEEGEGEEEEGEGEEE---EGEGEEEEGEGKGEEEGEEGE--GEEEG-EEGEGEGEE 880
Query: 90 EHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGK-EEHLEEEEYLG--KEGYL 146
E E E E G EEEE E E G EG EEEE GK EE EE E G +EG
Sbjct: 881 EEGEGEGEEEGEGEGEEEEGEGEGEEEG-EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEG 939
Query: 147 EKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKE 204
E ED E + + EEEE G+ E + E E EEEE + E +G+E
Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEE 997
Score = 55.1 bits (131), Expect = 2e-07
Identities = 70/191 (36%), Positives = 94/191 (49%), Gaps = 21/191 (10%)
Query: 30 EKEDTEVELDEESLQ-----DESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEE 84
E+E+ E + +EE + +E EGE E E EEE + E EE G+ E +E E
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEG-EGEEEEGEWEGEEEEGEGEGEEEGE 971
Query: 85 YLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLG---KEGYLEEEEYLGKEEHLEEEEYLG 141
G+E E EE E G EEEE EE E G +EG E EE +EE E E G
Sbjct: 972 GEGEEGEGEGEEE-EGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE---EEEGEVEGEVEG 1027
Query: 142 KEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLD 201
+EG E E+ EE + G++ E E +++ EE E+EE +E E+ E D
Sbjct: 1028 EEGEGEGEE--EEGEEEGEEREKEGEGEENRRNREEE----EEEEGKYQETGEEENERQD 1081
Query: 202 GKENLYKKYLK 212
G+E YKK K
Sbjct: 1082 GEE--YKKVSK 1090
Score = 54.3 bits (129), Expect = 4e-07
Identities = 59/168 (35%), Positives = 80/168 (47%), Gaps = 18/168 (10%)
Query: 45 DESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYL 104
+E GE E++ EEEE+ E E GKEE EE +E+ E + E+AG
Sbjct: 728 EEGGEEEHGEGEEEEGDREEEEEKEGE---GKEEGEGEEVEGEREKEEGERKKEERAG-- 782
Query: 105 EEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEE---------EEYLGKEGYLEKEDYIEEV 155
+EE EEE G +G EEEE G+ E EE EE G+ E+E EE
Sbjct: 783 -KEEKGEEE---GDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838
Query: 156 DYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGK 203
+ G++ E EE G+ EE + E EE EE E +EE +G+
Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGE 886
Score = 51.6 bits (122), Expect = 2e-06
Identities = 72/185 (38%), Positives = 90/185 (48%), Gaps = 15/185 (8%)
Query: 30 EKEDTEV--ELDEESLQDESPFSPEG----ESLEDKEYLEEEEDL-EEEEYLGKEEYLKE 82
E+E+TE E EE + E EG E E++ EEEE EEEE G+EE E
Sbjct: 797 EEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEE---E 853
Query: 83 EEYLGKEEHLE---EEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEY 139
E G+EE E EEE E G EEEE E E G EG EEEE G+ E E E
Sbjct: 854 GEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEG-EGEGEEEEGEGEGEEEGEGEG 912
Query: 140 LGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEEN 199
+EG + E+ EE + G++ E E G+ EEE E EE E E E+ E
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972
Query: 200 LDGKE 204
+G+E
Sbjct: 973 -EGEE 976
Score = 49.7 bits (117), Expect = 9e-06
Identities = 59/188 (31%), Positives = 88/188 (46%), Gaps = 21/188 (11%)
Query: 32 EDTEVELDEESLQDESPFSPEG-------ESLEDKEYLEEEEDLEEEEYLGKEEYLKEEE 84
+ EV + E+ PEG E E+ ++EE + E+ G+ E + E
Sbjct: 632 DKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE 691
Query: 85 YLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLE------EEEYLGKEEHLEEEE 138
G++E E+EE+ ++ G EE+E E E+ KE E EE G+EE + EE
Sbjct: 692 --GEKELAEKEEWKKRDG--EEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREE 747
Query: 139 YLGKEGYLEKEDYIEEVDYLGKKAYLE--EEEYLGKKSYLEEEKALEKEENLEEEEALEK 196
KEG ++E EEV+ +K E +EE GK+ EEE ++ E EEE
Sbjct: 748 EEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEG--DQGEGEEEETEGRG 805
Query: 197 EENLDGKE 204
EE +G E
Sbjct: 806 EEKEEGGE 813
Score = 49.7 bits (117), Expect = 9e-06
Identities = 56/177 (31%), Positives = 82/177 (46%), Gaps = 18/177 (10%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEE-----DLEEEEYLGKEEYLKEEE 84
E+E+ E E +EE + E EGE E + EEEE + EE E G+EE EEE
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008
Query: 85 YLGKEEHLEEE--------EYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEE 136
G+ E EEE E E G EEEE EE E KEG EE +EE EE
Sbjct: 1009 --GEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066
Query: 137 EEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEA 193
+Y + E+E+ ++ + K + ++ GK +++ + N +E+ +
Sbjct: 1067 GKY---QETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRS 1120
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/185 (35%), Positives = 89/185 (48%), Gaps = 24/185 (12%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDL---EEEEYLGKEEYLKEEEYL 86
EKE+ E + +E + ++E +GE D+ EEEE EE+E G+ E + EE
Sbjct: 769 EKEEGERKKEERAGKEE-----KGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGK 823
Query: 87 GK----EEHLEEEEY----LEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEE 138
G+ EE E EE E+ G EEEE + E G+EG EEE G+ E EEE
Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE- 882
Query: 139 YLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEE 198
EG E+E E + G+ EE E G+ EEE + EE EE E +EE
Sbjct: 883 ---GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGE----EEEGEGKGEEEGEEGEGEGEEE 935
Query: 199 NLDGK 203
+G+
Sbjct: 936 EGEGE 940
Score = 40.4 bits (93), Expect = 0.006
Identities = 52/187 (27%), Positives = 80/187 (42%), Gaps = 25/187 (13%)
Query: 33 DTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDL-------EEEEYLGKEEYLKEEEY 85
D EVE+ EE E +G +E++E EE++ E+ E L + K E
Sbjct: 581 DEEVEIPEEK---EGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVS 637
Query: 86 LGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEG- 144
GK + + E E G + EE G E + +EE G+++ E EG
Sbjct: 638 EGKAKSVGEAE----DGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGE 693
Query: 145 --YLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDG 202
EKE++ KK EE+E ++ ++E+ E EE EEE +EE D
Sbjct: 694 KELAEKEEW--------KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDR 745
Query: 203 KENLYKK 209
+E K+
Sbjct: 746 EEEEEKE 752
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 64.7 bits (156), Expect = 3e-10
Identities = 61/195 (31%), Positives = 100/195 (51%), Gaps = 30/195 (15%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKE--YLEEEEDLEEEE--YLGKEEYLKEEEY 85
E E+ E +E + E + E L ++E E+EE L E+E +EE L+E+E
Sbjct: 252 EHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQE- 310
Query: 86 LGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGY 145
E E+EE L + +EE E+E+ G+E LEE E L ++E +EE+ E
Sbjct: 311 ---ERLCEQEERLRE----QEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQ----ERL 359
Query: 146 LEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENL--DGK 203
LE+E +EEV EE L ++ ++++ L ++E L+E E L + E + G
Sbjct: 360 LERERLLEEV-----------EELLEQERLRQQDERLWQQETLQELERLRELERMLELGW 408
Query: 204 ENLYKKYLKEPKASY 218
E LY++ EP++ +
Sbjct: 409 EALYEQ-RAEPRSGF 422
Score = 60.8 bits (146), Expect = 4e-09
Identities = 69/238 (28%), Positives = 114/238 (47%), Gaps = 32/238 (13%)
Query: 6 NQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEE 65
NQ + P PP P + L E EL+ Q ++ +E+ + L
Sbjct: 142 NQTAEPLAPEPPAGPS-KVEQLQDETNHLRKELESVGRQLQA-------EVENNQMLSLL 193
Query: 66 EDLEEEEYLGKEEYLKEEEYLGKEEH---LEEEEYL---EKAGYLEEEEYIEEEEYL--G 117
+EE +EE L+E+E +E+ E+EE L E+ +EE E+EE L
Sbjct: 194 NRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREH 253
Query: 118 KEGYLEEEEYL-GKEEHLEEEE---YLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKK 173
+E E+EE L +EE L E+E + +E E+E+ + E + + E+EE L +
Sbjct: 254 EERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQE----ERLCEQEERLRE- 308
Query: 174 SYLEEEKALEKEENL-EEEEALEKEENLDGKENL---YKKYLKEPKASYSSQTMLLRD 227
+EE+ E+EE L E+EE L ++E L G+E L +K L++ + + +L R+
Sbjct: 309 ---QEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERE 363
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 63.9 bits (154), Expect = 5e-10
Identities = 51/177 (28%), Positives = 97/177 (54%), Gaps = 16/177 (9%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKE 89
EKE+ EL EE + ++ + E +++E + E+E +E+E + + +EE+ +E
Sbjct: 374 EKEEKIREL-EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE---AKMWRQEEKIREQE 429
Query: 90 EHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKE 149
E + E+ EK + +EE+ E+E+ +E E+EE +EE + E+E + ++ EK
Sbjct: 430 EKIREQ---EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ--KEKM 484
Query: 150 DYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL--EEEEALEKEENLDGKE 204
E++ +K + +EE K + +EEK E+EE + +EE+ E+EE + +E
Sbjct: 485 HEQEKIRKQEEKVWRQEE-----KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE 536
Score = 61.6 bits (148), Expect = 2e-09
Identities = 57/190 (30%), Positives = 105/190 (55%), Gaps = 17/190 (8%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESL----EDKEYLEEEEDLEEEEYLGKEEYL---KEE 83
+++ +++ EE +Q++ E E E+K +EE E+EE + ++E + KEE
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 84 EYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEE---YL 140
+ EE + E+E EK LEE+ + E+E+ +E +EEE + ++E +E+E +
Sbjct: 364 KMRRLEEMMWEKE--EKIRELEEKMH-EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 420
Query: 141 GKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL-EEEEALEKEEN 199
+E E+E+ I E + KK + +EE+ ++ EEEK E+EE +EE+ E+EE
Sbjct: 421 QEEKIREQEEKIREQE---KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477
Query: 200 LDGKENLYKK 209
KE ++++
Sbjct: 478 WRQKEKMHEQ 487
Score = 58.5 bits (140), Expect = 2e-08
Identities = 52/193 (26%), Positives = 105/193 (54%), Gaps = 20/193 (10%)
Query: 32 EDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEE---YLKEEEYLGK 88
E ++ +E+ + E + E + E +E ++E + E+E + K+E + +EE+ +
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
Query: 89 EEHLEEEE---YLEKAGYLEEEEYIEEEEYLGKEG---YLEEEEYLGK-EEHLEEEEYLG 141
EE + E+E + ++ E+EE I E+E +E E+EE +G+ EE ++E+E +
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
Query: 142 K--EGYLEKEDYI----EEVDYLGKKAYLEEEEYLGKKSYLEE--EKALEKEENL--EEE 191
+ E E+E+ I E++ +K + +EE+ ++ ++E EK E+EE + +EE
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
Query: 192 EALEKEENLDGKE 204
+ E+EE + +E
Sbjct: 628 KMQEQEEKMRRQE 640
Score = 56.6 bits (135), Expect = 8e-08
Identities = 54/209 (25%), Positives = 110/209 (52%), Gaps = 28/209 (13%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDL---EEEEYLGKEEYLKEEE--- 84
+E E+ EE ++++ + E + ++E + ++E+ +EE+ +EE ++E+E
Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518
Query: 85 YLGKEEHLEEEEYL--EKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGK 142
+ +E+ E+EE + ++ E+EE ++E+E E E+EE + ++E + +E
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQE----EKMGEQEEKMQEQEKMRRQE---- 570
Query: 143 EGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEE--ALEKEENL 200
E E+E+ I E +K + E+E +K + +EEK E+EE ++E+E E+EE +
Sbjct: 571 EKIREQEEKIRE-----QKEKIREQE---EKIWEQEEKIREQEEMMQEQEEKMWEQEEKM 622
Query: 201 DGKENLYKKYLKEPKASYSSQTMLLRDAR 229
+E K +E K + M ++ R
Sbjct: 623 CEQEE--KMQEQEEKMRRQEEKMWEQEVR 649
Score = 52.0 bits (123), Expect = 2e-06
Identities = 48/180 (26%), Positives = 99/180 (55%), Gaps = 28/180 (15%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESL-EDKEYLEEEEDL--EEEEYLG-KEEYLKEEEY 85
++E+ E +E+ + E + E + E +E + E+E++ E+EE +G +EE ++E+E
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK 565
Query: 86 LGKEEH--LEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKE 143
+ ++E E+EE + E++E I E+E E E+EE + ++E + +E+
Sbjct: 566 MRRQEEKIREQEEKIR-----EQKEKIREQE----EKIWEQEEKIREQEEMMQEQ----- 611
Query: 144 GYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL--EEEEALEKEENLD 201
E++ + +E ++ ++E+E +K +EEK E+E L +EE+ E +E+L+
Sbjct: 612 ---EEKMWEQEEKMCEQEEKMQEQE---EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/215 (26%), Positives = 112/215 (52%), Gaps = 30/215 (13%)
Query: 21 QYSTQNLPSEKEDTEVELDEESLQDESP-FSPEGESLEDKEYLEEEED--------LEEE 71
Q + + L + E ++ L ++ LQ E+ E +S+ K + EE+ +EE
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
Query: 72 EYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYL--EEEEYLG 129
+ +EE ++E E E+ E+EE + + +EE+ E+EE + ++ + E+EE +
Sbjct: 301 KMWRQEEKIQEWE----EKIQEQEEKIRE----QEEKIREQEEKMRRQEEMMWEKEEKMR 352
Query: 130 KEEHL--EEEEYLGK--EGYLEKEDYIEEVD---YLGKKAYLEEEEYLGKKSYLEEEKAL 182
++E + E+EE + + E EKE+ I E++ + +K +EE+ ++ E+EK
Sbjct: 353 RQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 412
Query: 183 EKEENL--EEEEALEKEENLDGKENLYKKYLKEPK 215
E+E + +EE+ E+EE + +E K + +E K
Sbjct: 413 EQEAKMWRQEEKIREQEEKI--REQEKKMWRQEEK 445
Score = 40.8 bits (94), Expect = 0.004
Identities = 86/432 (19%), Positives = 167/432 (38%), Gaps = 59/432 (13%)
Query: 77 EEYLKEEEYLGKEEH---LEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEH 133
EE KE + L E + + +EE EK L+E+ + E E E L +E K
Sbjct: 196 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK--SEIQLNVKELKRK--- 250
Query: 134 LEEEEYLGKEGYLEKEDYIEEVDYLGKK---------AYLEEEEYLGKKSYLEEEKALEK 184
LE + L L ++ E D+LGK+ A +EE E + + +EEK +
Sbjct: 251 LERAKLL-----LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ 305
Query: 185 EENL---------EEEEALEKEENLDGKENLYKK-----YLKEPKASYSSQTM-----LL 225
EE + +EE+ E+EE + +E ++ + KE K + M +
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 226 RDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTA 285
R + L + E + E + +R + W R
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW---RQE 422
Query: 286 VKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVE 345
K + + + ++ EE ++ + + ++EE E +E W + ++
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE---QEEMWR-------QEEKIR 472
Query: 346 DLDENFLNSSYQTVFKTIIKEMAAHNELEEDFDIPLTKLLESENR-WKLVIMLKKNYEKF 404
+ +E + + I K+ EE K+ E E + W+ +++ EK
Sbjct: 473 EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI 532
Query: 405 KETILRIKRRRE-AQKLTEMTSFTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLERDKE- 462
+E +I+ + E Q+ E M + + + E+I++ + + +K+ R++E
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
Query: 463 --WIQKKTVVHQ 472
W Q++ + Q
Sbjct: 593 KIWEQEEKIREQ 604
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 63.5 bits (153), Expect = 6e-10
Identities = 74/229 (32%), Positives = 100/229 (43%), Gaps = 27/229 (11%)
Query: 13 PPHPPTTPQYSTQNLPSEK---EDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLE 69
PP PP P LP + E T +L+++ S E++E EEEE+ E
Sbjct: 841 PPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEE 900
Query: 70 EEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLG 129
EEE +E++ +EEE +EEEY E+ EEEE EEE+ +EG LEEEE
Sbjct: 901 EEEEEEEEDFEEEEE--------DEEEYFEEE---EEEEEEFEEEFEEEEGELEEEE--- 946
Query: 130 KEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL- 188
+EE EEEE L + LE EV+ +S + + E E L
Sbjct: 947 EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLL 1006
Query: 189 --EEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGP 235
EE E+E D L + L SQ + R+ SP AGP
Sbjct: 1007 LEVEEPGTEEERGADTAPTLAPEAL-------PSQGEVEREGESPAAGP 1048
>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
subfamily a-like [Homo sapiens]
Length = 432
Score = 62.4 bits (150), Expect = 1e-09
Identities = 64/218 (29%), Positives = 104/218 (47%), Gaps = 33/218 (15%)
Query: 6 NQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEE 65
NQ + P PP P + L E EL+ Q ++ +E+ + L
Sbjct: 142 NQTAEPLAPQPPAGPS-KVEQLQDETNHLRKELESVGRQLQA-------EVENNQMLSLL 193
Query: 66 EDLEEEEYLGKEEYLKEEE--YLGKEEHL-EEEEYLEKAGYLEEEEYIEEEEYLGKEGYL 122
+EE +EE L+E+E +EE L E+EE L + +EE E+E+ G+E L
Sbjct: 194 NRRQEERLREQEERLREQEERLCEQEERLCEQEERLRE----QEERLCEQEKLPGQERLL 249
Query: 123 EEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKAL 182
EE E L K+E +EE+ E LE+E ++EV EE L ++ ++++ L
Sbjct: 250 EEVEKLLKQERRQEEQ----ERLLERERLLDEV-----------EELLEQERLRQQDERL 294
Query: 183 EKEENLEEEEALEKEENL--DGKENLYKKYLKEPKASY 218
++E L E E L + E + G E LY++ EP++ +
Sbjct: 295 WQQETLRELERLRELERMLELGWEALYEQ-RAEPRSGF 331
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 62.4 bits (150), Expect = 1e-09
Identities = 93/455 (20%), Positives = 193/455 (42%), Gaps = 50/455 (10%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKE---YLEEEEDLEEEEYLGK-EEYLKEEEYL 86
+++ E+ E+ L+++ + E ++++E + +EE+ E+EE + + EE L E+E
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 87 GKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYL 146
+E+ + + E+ +E +EE +E E+EE + +EE + E E +E
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE--- 403
Query: 147 EKEDYIEEVDYLGKKA----YLEEEEYLGKKSYLEEEKALEKEENLEEEEAL-EKEENLD 201
E+E E+ + + K+ EE+E+ ++ ++EK E+E+ E+EE + E+EE +
Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 463
Query: 202 GKENLY---KKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESA 258
+E ++ KK ++ K M ++ + D E
Sbjct: 464 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ--------------EERM 509
Query: 259 TESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTT-----KLAPEEHVNTKV 313
E E L R + + W + K + K EQE T K+ EE + +
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEE---KMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Query: 314 QQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNEL 373
++ +EE + +E + +E + + E + ++ + K +E +
Sbjct: 567 KKMREEEEMMREQEEKMQE--QEEKMREQEEKMWEQE--EKMQEQEEKMWEQEEKMWEQE 622
Query: 374 EEDFDIPLTKLLESEN-RWKLVIMLKKNYEKFKETILRIKRRREAQKLTEMTSFTFHLMS 432
EED K+ E E W+ +++ EK E K R + +K+ E
Sbjct: 623 EED------KMQEQEEMMWEQEEKMQEQEEKMWEQ--EEKMREQEEKMREQEEKMQGQEE 674
Query: 433 KPTPEKPETEEIQKPQRVVHHRKKLERDKEWIQKK 467
K ++ + + ++ R + + + +K W Q++
Sbjct: 675 KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEE 709
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/178 (28%), Positives = 97/178 (54%), Gaps = 11/178 (6%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYL-GKEEYLKEEEYLGK 88
EKE+ E + Q+E + ++K+ ++EE + EEE + +E+ ++EEE + +
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 577
Query: 89 EEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEK 148
E+ + +E EK EE+ + +EE+ +E + E+E E+ E++ +E E+
Sbjct: 578 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ 637
Query: 149 EDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL--EEEEALEKEENLDGKE 204
E+ ++E + +K + +EE K +EEK E+EE + +EE+ E+EE + G+E
Sbjct: 638 EEKMQEQE---EKMWEQEE-----KMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687
Score = 59.3 bits (142), Expect = 1e-08
Identities = 59/216 (27%), Positives = 105/216 (48%), Gaps = 33/216 (15%)
Query: 20 PQYSTQNLPSEKEDTEVELDEESL-----------QDESPFSPEGESLEDKEYL------ 62
PQ T L E E EL E+ Q+E EG+ E +E +
Sbjct: 225 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKR 284
Query: 63 --EEEEDL-EEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKE 119
E+E++L E+E+ L +++ L+E+E +E+ + E EK EE+ + +EE +E
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
Query: 120 GYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEE 179
+ E+E +++ EE + E EKE+ + E + K + +EE+ ++ E E
Sbjct: 345 KQMREQEQKMRDQ--EERMWEQDERLREKEERMREQE----KMWEQEEKMQEEERIRERE 398
Query: 180 KALEKEENL--EEEEALEKEENLDGKENLYKKYLKE 213
K + +EE E+EE ++K+E EN++++ KE
Sbjct: 399 KKMREEEETMREQEEKMQKQE-----ENMWEQEEKE 429
Score = 55.5 bits (132), Expect = 2e-07
Identities = 52/190 (27%), Positives = 104/190 (54%), Gaps = 16/190 (8%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDL--EEEEYLGKEE---YLKEEE 84
E+E + +E+ ++E E + E++E + E+E+ E+EE + ++E + +EE+
Sbjct: 544 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603
Query: 85 YLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYL-GKEEHLEEEEYLGKE 143
+EE + E+E EK EEE+ ++E+E E E+EE + +EE + E+E +E
Sbjct: 604 MQEQEEKMWEQE--EKMWEQEEEDKMQEQE----EMMWEQEEKMQEQEEKMWEQEEKMRE 657
Query: 144 GYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYL--EEEKALEKEENL--EEEEALEKEEN 199
+ + E++ +K +EE+ G++ + +EEK +EE + +EE+ +EE
Sbjct: 658 QEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEK 717
Query: 200 LDGKENLYKK 209
+ G+E + +K
Sbjct: 718 MWGQEEMREK 727
Score = 55.1 bits (131), Expect = 2e-07
Identities = 64/323 (19%), Positives = 146/323 (45%), Gaps = 53/323 (16%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKE 89
++E+ E DE + E + + E +E ++EEE + E +E+ ++EEE E
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE-----REKKMREEE----E 406
Query: 90 EHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKE 149
E+EE ++K EE + +EE+ ++ E++E L ++E ++E+E E E+E
Sbjct: 407 TMREQEEKMQKQ---EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE----EKIWEQE 459
Query: 150 DYIEEVDYL-GKKAYLEEEEYLGKKS---YLEEEKALEKEENL--EEEEALEKEENLDGK 203
+ I + + + G++ + +E + ++ + +EEK ++E+ + +EE E++E L K
Sbjct: 460 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 204 ENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSE 263
E + ++E K + + + + ++ + E T E
Sbjct: 520 E----ERMREQKKMWQQEEKMREEKKTQE----------------------QEKKTWDQE 553
Query: 264 LLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLE 323
+ R + + + ++ + K + ++E + + + Q++EE + E
Sbjct: 554 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 613
Query: 324 FASKENFWDGITDESIDKLEVED 346
+E W+ E DK++ ++
Sbjct: 614 --QEEKMWE---QEEEDKMQEQE 631
Score = 53.1 bits (126), Expect = 8e-07
Identities = 53/191 (27%), Positives = 102/191 (53%), Gaps = 31/191 (16%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESL-EDKEYLEEEED--LEEEEYLGKEEYLKEEEYL 86
E+E+ E +E+ + E + E + E +E ++E+E+ E+EE + ++E EE+ +
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE---EEDKM 627
Query: 87 GKEEHL--EEEEYL--EKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGK 142
++E + E+EE + ++ E+EE + E+E +E +EE+ G+EE + E+E
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE---QEEKMQGQEEKMREQE---- 680
Query: 143 EGYLEKEDYIEEVDYLGKKAYLEEEEYLG--KKSYLEEEKALEKEENL-EEEEALEKEEN 199
E++ +K +EE+ G +K + +EEK +EE + +EE EKEE
Sbjct: 681 ----------EKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEER 730
Query: 200 L-DGKENLYKK 209
+ D KE + ++
Sbjct: 731 IRDQKEKMQER 741
Score = 52.8 bits (125), Expect = 1e-06
Identities = 49/174 (28%), Positives = 87/174 (50%), Gaps = 16/174 (9%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESL---EDKEYLEEEEDLEEEEYLGKEEYLKEEEYL 86
E+E+ E +E+ + E + E + E+K + +EEED +E+ EE + E+E
Sbjct: 585 EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ----EEMMWEQEEK 640
Query: 87 GKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYL--EEEEYLGKEEHLEEEEYLGKEG 144
+E+ + E EK EE+ +EE+ G+E + +EE+ G+EE + E+E G
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE-KMRG 699
Query: 145 YLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEE 198
EK EE K + +EE+ G++ E+E+ + ++ +E E EE
Sbjct: 700 QEEKMWGQEE------KMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 51.2 bits (121), Expect = 3e-06
Identities = 49/210 (23%), Positives = 105/210 (50%), Gaps = 35/210 (16%)
Query: 21 QYSTQNLPSEKE-----------DTEVELDEESLQDESPFSPEGESLEDKEYLEEEED-L 68
++ Q LP +KE + ++ EE ++D+ + + + +E + E+ED +
Sbjct: 429 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 488
Query: 69 -EEEEYLGKEE----------YLKEEEYLGKEEHLEEEEYL-EKAGYLEEEEYIEEEE-- 114
E+EE + +E + ++E KEE + E++ + ++ + EE+ +E+E
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548
Query: 115 -YLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKK 173
+ +E EEE +E+ + EEE + +E + ++ E++ +K + +EE K
Sbjct: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE-----K 603
Query: 174 SYLEEEKALEKEENL---EEEEALEKEENL 200
+EEK E+EE + EEE+ ++++E +
Sbjct: 604 MQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633
Score = 50.1 bits (118), Expect = 7e-06
Identities = 40/132 (30%), Positives = 71/132 (53%), Gaps = 9/132 (6%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESL-EDKEYLEEEEDL---EEEEYLGKEEYLKEEE- 84
E+ED E +E + E + E + E +E + E+E+ +EE+ G+EE ++E+E
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 85 -YLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYL-EEEEYLGKEEHLEEEEYLGK 142
G+EE + E+E EK EE+ + +EE+ G+E + +EE KEE + +++ +
Sbjct: 682 KMQGQEEKMREQE--EKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ 739
Query: 143 EGYLEKEDYIEE 154
E E E+ E
Sbjct: 740 ERLPEHEERCSE 751
Score = 45.4 bits (106), Expect = 2e-04
Identities = 91/439 (20%), Positives = 182/439 (41%), Gaps = 51/439 (11%)
Query: 59 KEYLEEEEDLEEEEY---LGKEEYLKEEEYLGKEEHLEEEEYLE-KAGYLEEEEYIEEEE 114
+E +E + L E Y + EE K+ L ++ L E E E + E + +E +
Sbjct: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
Query: 115 YLGKE---GYLEEEEYLGKEEHLEEEEYLGK--EGYLEKEDYIEEVDYLGKKAYLEEEEY 169
+L + L+EE + +EE E+E+ + K E +E+ + E + GK EE+
Sbjct: 222 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE--GKMREQEEKMR 279
Query: 170 LGKKSYLEEEKAL-EKEENLEEEEAL-EKEENLDGKENLYKKYLKEPKASYSSQTMLLRD 227
+K E+EK L E+E+ L E++ L E+EE + +E K + +E K + M ++
Sbjct: 280 RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE--KMWEQEEKMREQEEKMWRQE 337
Query: 228 ARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYD----- 282
R + + E E E L R + + W +
Sbjct: 338 ERLWEQEKQMREQEQKM-------RDQEERMWEQDERLREKEERMREQEKMWEQEEKMQE 390
Query: 283 ----RTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLEFASKENFWD-GITDE 337
R K ++ + ET +E K+ +E + ++K+ + KE W+ E
Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450
Query: 338 SIDKL-----EVEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDFDIPLTKLLESENR-W 391
+K+ ++ D +E + + + ++ E EE K+ + E R W
Sbjct: 451 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
Query: 392 KLVIMLKKNYEKFKE---TILRIKRRREAQKLTEMTSFTFHLMSKPTPEKPETEEIQKPQ 448
+ L++ E+ +E + ++ RE +K E T+ + E++++ +
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW----------DQEEKMREEE 560
Query: 449 RVVHHRKKLERDKEWIQKK 467
R+ KK+ ++E ++++
Sbjct: 561 RMREREKKMREEEEMMREQ 579
Score = 30.8 bits (68), Expect = 4.4
Identities = 32/120 (26%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKE--YLEEEEDL--EEEEYLGKEEYL--KEE 83
E+E+ E +E+ E + E ++ +E E+EE + +EE+ G+EE + +EE
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEE 716
Query: 84 EYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKE 143
+ G+EE + E+E + + +E + E E E L + L H E G E
Sbjct: 717 KMWGQEE-MREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGE 775
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 62.4 bits (150), Expect = 1e-09
Identities = 54/179 (30%), Positives = 100/179 (55%), Gaps = 19/179 (10%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKE 89
EKE+ EL EE + ++ + E +++E + E+E +E+E + + +EE+ +E
Sbjct: 435 EKEEKIREL-EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE---AKMWRQEEKIREQE 490
Query: 90 EHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEE--YLGKEGYLE 147
E + E+E EK + +EE+ E+E+ +E E+EE +EE + E+E + KE E
Sbjct: 491 EKIREQE--EKM-WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE 547
Query: 148 KEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL--EEEEALEKEENLDGKE 204
+E+ I + + +K + +EE K + +EEK E+EE + +EE+ E+EE + +E
Sbjct: 548 QEEKIRKQE---EKMWRQEE-----KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Score = 58.5 bits (140), Expect = 2e-08
Identities = 48/199 (24%), Positives = 107/199 (53%), Gaps = 22/199 (11%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDL--EEEEYLGKEEYLKEEEYLGK 88
+++ ++ EE + + E E + ++E +E+E++ +EE+ +EE +++E + +
Sbjct: 488 EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE 547
Query: 89 EEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEK 148
+E E+ E+ + +EE+ ++EE + + +EE+ +EE + E+E E E+
Sbjct: 548 QE--EKIRKQEEKMWRQEEKMHDQEEKIRE----QEEKVWRQEEKIREQE----EKIREQ 597
Query: 149 EDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYK 208
E+ I E + + + E+EE +G+ +EEK E+EE ++E+E EK + K +
Sbjct: 598 EEKIREQEEMTQ----EQEEKMGE----QEEKMCEQEEKMQEQE--EKMRRQEEKIREQE 647
Query: 209 KYLKEPKASYSSQTMLLRD 227
K ++E + Q ++++
Sbjct: 648 KKIREQEEKIREQEEMMQE 666
Score = 57.8 bits (138), Expect = 3e-08
Identities = 55/196 (28%), Positives = 104/196 (53%), Gaps = 23/196 (11%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESL----EDKEYLEEEEDLEEEEYLGKEEYL---KEE 83
+++ +++ EE +Q++ E E E+K +EE E+EE + ++E + KEE
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424
Query: 84 EYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEE---YL 140
+ +EE + E+E EK LEE+ + E+E+ +E +EEE + ++E +E+E +
Sbjct: 425 KMRRQEEMMWEKE--EKIRELEEKMH-EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 481
Query: 141 GKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL-------EEEEA 193
+E E+E+ I E + +K + +EE+ ++ EEEK E+EE E+EE
Sbjct: 482 QEEKIREQEEKIREQE---EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Query: 194 LEKEENLDGKENLYKK 209
++E + +E +K
Sbjct: 539 WRQKEKIHEQEEKIRK 554
Score = 56.2 bits (134), Expect = 1e-07
Identities = 59/220 (26%), Positives = 112/220 (50%), Gaps = 30/220 (13%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLG--KEEYLKEEEYLGK 88
+++ ++ EE + ++ E + E +E +EE + E+E + KE+ ++EE + K
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554
Query: 89 EE----------HLEEEEYLEKAGYL-EEEEYIEEEEYLGKEGYLEEEEYLGKEEHL--E 135
+E H +EE+ E+ + +EE I E+E E E+EE + ++E + E
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE----EKIREQEEKIREQEEMTQE 610
Query: 136 EEEYLG--KEGYLEKEDYIEEVDYLGKKAYLEEEEY--LGKKSYLEEEKALEKEENLEEE 191
+EE +G +E E+E+ ++E + +K +EE+ KK +EEK E+EE ++E+
Sbjct: 611 QEEKMGEQEEKMCEQEEKMQEQE---EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 667
Query: 192 E--ALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDAR 229
E E+EE + +E K +E K + M ++ R
Sbjct: 668 EEKMWEQEEKMCEQEE--KMQEQEEKMRRQEEKMWEQEVR 705
Score = 48.9 bits (115), Expect = 2e-05
Identities = 56/215 (26%), Positives = 113/215 (52%), Gaps = 30/215 (13%)
Query: 21 QYSTQNLPSEKEDTEVELDEESLQDESP-FSPEGESLEDKEYLEEEED--------LEEE 71
Q + + L + E ++ L ++ LQ E+ E +S+ K + EE+ +EE
Sbjct: 302 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 361
Query: 72 EYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYL--EEEEYLG 129
+ +EE ++E E E+ E+EE + + +EE+ E+EE + ++ + E+EE +
Sbjct: 362 KMWRQEEKIQEWE----EKIQEQEEKIRE----QEEKIREQEEKMRRQEEMMWEKEEKMR 413
Query: 130 KEEHL--EEEEYLGKEGYL--EKEDYIEEVD---YLGKKAYLEEEEYLGKKSYLEEEKAL 182
++E + E+EE + ++ + EKE+ I E++ + +K +EE+ ++ E+EK
Sbjct: 414 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 473
Query: 183 EKEENL--EEEEALEKEENLDGKENLYKKYLKEPK 215
E+E + +EE+ E+EE + +E K + +E K
Sbjct: 474 EQEAKMWRQEEKIREQEEKI--REQEEKMWRQEEK 506
Score = 45.8 bits (107), Expect = 1e-04
Identities = 87/462 (18%), Positives = 181/462 (39%), Gaps = 67/462 (14%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEE----DLEEEEYLGKEEYL 80
+ L E++ +EL ++ DE + L++K L E E L +E K E
Sbjct: 257 EELTKERDALSLELYRNTITDEE-LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 315
Query: 81 K----EEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEE 136
K +++ + +HL +E A + + +EE E + +EE+ +EE ++E
Sbjct: 316 KLLLPQQQLQAEADHLGKELQSVSA---KLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 372
Query: 137 EEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEAL-- 194
E E E+E+ I E +EEK E+EE + +E +
Sbjct: 373 WE----EKIQEQEEKIRE----------------------QEEKIREQEEKMRRQEEMMW 406
Query: 195 EKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPV 254
EKEE + +E + + KE K + M ++ + + L +
Sbjct: 407 EKEEKMRRQEEM--MWEKEEKMRRQEEMMWEKEEKIRE---------LEEKMHEQEKIRE 455
Query: 255 SESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQ 314
E + E + +R + W + ++ + K ++E + + H K++
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEE-KIREQEEKIREQEEKMWRQEEKIHEQEKIR 514
Query: 315 QKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNELE 374
++++ +E W +E I + E + ++ + + K K ++
Sbjct: 515 EEEKRQ-----EQEEMWR--QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH 567
Query: 375 EDFDIPLTKLLESENR-WKLVIMLKKNYEKFKETILRIKRRRE-AQKLTEMTSFTFHLMS 432
+ + K+ E E + W+ +++ EK +E +I+ + E Q+ E M
Sbjct: 568 DQEE----KIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 623
Query: 433 KPTPEKPETEEIQKPQ--RVVHHRKKLERDKEWIQKKTVVHQ 472
+ + E EE + Q ++ KK+ +E I+++ + Q
Sbjct: 624 EQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665
Score = 42.7 bits (99), Expect = 0.001
Identities = 43/164 (26%), Positives = 81/164 (49%), Gaps = 21/164 (12%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDL----EEEEYLGKEEYLKEEEY 85
E+E+ +E+ + E + E + ++E + +E++ +EE+ +EE ++E+E
Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE- 633
Query: 86 LGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGY 145
K EE+ ++ E+EE I E+E + +E +EE+ +EE + E+E
Sbjct: 634 -EKMRRQEEKIREQEKKIREQEEKIREQEEMMQE---QEEKMWEQEEKMCEQE------- 682
Query: 146 LEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLE 189
EK EE ++ E+E L + +EEK E +E+LE
Sbjct: 683 -EKMQEQEEKMRRQEEKMWEQEVRLRQ----QEEKMQEHQEHLE 721
>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
Length = 432
Score = 62.4 bits (150), Expect = 1e-09
Identities = 64/218 (29%), Positives = 104/218 (47%), Gaps = 33/218 (15%)
Query: 6 NQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEE 65
NQ + P PP P + L E EL+ Q ++ +E+ + L
Sbjct: 142 NQTAEPLAPQPPAGPS-KVEQLQDETNHLRKELESVGRQLQA-------EVENNQMLSLL 193
Query: 66 EDLEEEEYLGKEEYLKEEE--YLGKEEHL-EEEEYLEKAGYLEEEEYIEEEEYLGKEGYL 122
+EE +EE L+E+E +EE L E+EE L + +EE E+E+ G+E L
Sbjct: 194 NRRQEERLREQEERLREQEERLCEQEERLCEQEERLRE----QEERLCEQEKLPGQERLL 249
Query: 123 EEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKAL 182
EE E L K+E +EE+ E LE+E ++EV EE L ++ ++++ L
Sbjct: 250 EEVEKLLKQERRQEEQ----ERLLERERLLDEV-----------EELLEQERLRQQDERL 294
Query: 183 EKEENLEEEEALEKEENL--DGKENLYKKYLKEPKASY 218
++E L E E L + E + G E LY++ EP++ +
Sbjct: 295 WQQETLRELERLRELERMLELGWEALYEQ-RAEPRSGF 331
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 61.2 bits (147), Expect = 3e-09
Identities = 52/204 (25%), Positives = 106/204 (51%), Gaps = 28/204 (13%)
Query: 21 QYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESL---EDKEYLEEEEDLEEEEYLGKE 77
Q Q +K++ +V+ EE ++ + E E ++++ L+++E E+EE G++
Sbjct: 235 QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ 294
Query: 78 EYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEE 137
E E+ +EE + E+E + +EE+ E+EE +GK+ EE+ + KE+ E++
Sbjct: 295 E----EQMREQEEQMREQEEQMRE---QEEQMREQEEQMGKQ---EEQMWEQKEQMWEQK 344
Query: 138 EYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKE 197
E + K ++E E+ + + K +EE + K+ EE+ ++E+ ++EE + K+
Sbjct: 345 EQMWK----QEEQMGEQEEQMQK-----QEEQVRKQ---EEQMRKQEEQMRKQEEQMRKQ 392
Query: 198 ENLDGKENLYKKYLKEPKASYSSQ 221
E G++ K+ + E K Q
Sbjct: 393 EEQMGEQ---KEQMGEQKEQMREQ 413
Score = 60.8 bits (146), Expect = 4e-09
Identities = 48/192 (25%), Positives = 100/192 (52%), Gaps = 21/192 (10%)
Query: 21 QYSTQNLPSEKEDTEVELDEESL--QDESPFSPEGESLEDKEYLEEEEDL--EEEEYLGK 76
Q Q +K++ ++ EE + Q+E E + L+ KE E+EE +EE+ +
Sbjct: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
Query: 77 EEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEE-YLGKEGYLEEEEYLGKEEHL- 134
EE ++E+E +E+ + E E+ G EE+ + ++E+ + KE ++EE +G++E
Sbjct: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
Query: 135 --EEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEE 192
+EE+ +E + K++ + ++EE + K+ EE+ +KE+ E++E
Sbjct: 362 QKQEEQVRKQEEQMRKQE----------EQMRKQEEQMRKQ---EEQMGEQKEQMGEQKE 408
Query: 193 ALEKEENLDGKE 204
+ ++E G++
Sbjct: 409 QMREQEEQMGEQ 420
Score = 59.7 bits (143), Expect = 9e-09
Identities = 56/217 (25%), Positives = 111/217 (51%), Gaps = 21/217 (9%)
Query: 21 QYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYL 80
Q Q +K++ ++ EE ++ + GE E + EE+ +EE+ +EE +
Sbjct: 207 QMGEQEEQMQKQEEQMGEQEEQMRKQE--EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
Query: 81 KEEEYLGKEEHLEEEEYLEKAGYLEEEEYI-EEEEYLGK--EGYLEEEEYLGKEEH--LE 135
+E+E +E+ EE+ L++ E+EE E+EE + + E E+EE + ++E E
Sbjct: 265 REQEEQMREQ---EEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Query: 136 EEEYLGKEG---YLEKEDYIEEVDYLGKKAYL--EEEEYLGKKSYLEEEKALEKEENLEE 190
+EE +GK+ + +KE E+ + + K+ E+EE + K+ EE+ ++E+ ++
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ---EEQVRKQEEQMRKQ 378
Query: 191 EEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRD 227
EE + K+E K+ ++ + E K Q +R+
Sbjct: 379 EEQMRKQEEQMRKQ---EEQMGEQKEQMGEQKEQMRE 412
Score = 57.8 bits (138), Expect = 3e-08
Identities = 49/178 (27%), Positives = 96/178 (53%), Gaps = 19/178 (10%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEE--YLKEEEYLG 87
E+E E +E+ + E + E + + +EE+ ++EE +G++E K+EE +
Sbjct: 196 EQEGQMGEQEEQMGEQEEQMQKQEEQMGE----QEEQMRKQEEQMGEQEEQVQKQEEQVQ 251
Query: 88 K-EEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYL 146
K EE + ++E E+ EE+ +EE+ L ++ E+EE G++E E+ +E
Sbjct: 252 KQEEQMRKQE--EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ---EEQMR 306
Query: 147 EKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKE 204
E+E+ + E + + E+EE +GK+ EE+ +KE+ E++E + K+E G++
Sbjct: 307 EQEEQMREQE----EQMREQEEQMGKQ---EEQMWEQKEQMWEQKEQMWKQEEQMGEQ 357
Score = 55.8 bits (133), Expect = 1e-07
Identities = 48/161 (29%), Positives = 91/161 (56%), Gaps = 23/161 (14%)
Query: 52 EGESLEDKEYLEEEEDL--EEEEYLG--KEEYLKEEEYLG-KEEHLEEEEYLEKAGYLEE 106
EG+ E + + E+E E+EE +G +E+ K+EE +G +EE + ++E E+ G EE
Sbjct: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE--EQMGEQEE 241
Query: 107 EEYIEEEEYLGKEGYL--EEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYL 164
+ +EE+ +E + +EE+ +EE + E+E E L++++ E+ + G
Sbjct: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQE----EQMLKQKEQTEQEEQTG----- 292
Query: 165 EEEEYLGKKSYLEEEKALEKEENL-EEEEALEKEENLDGKE 204
E+EE + + +EE+ E+EE + E+EE + ++E GK+
Sbjct: 293 EQEEQMRE----QEEQMREQEEQMREQEEQMREQEEQMGKQ 329
Score = 50.1 bits (118), Expect = 7e-06
Identities = 45/179 (25%), Positives = 97/179 (54%), Gaps = 27/179 (15%)
Query: 21 QYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKE--YLEEEEDL--EEEEYLGK 76
Q Q +E+E+ E +E+ + E + E + ++E E+EE + +EE+ +
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336
Query: 77 EEYL---KEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEH 133
+E + KE+ + +E+ E+EE ++K +EE+ ++EE + K+ EE+ +E+
Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQK----QEEQVRKQEEQMRKQ---EEQMRKQEEQM 389
Query: 134 LEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEE 192
++EE +G+ +KE E+ K+ E+EE +G+ ++E+ ++EE++ E++
Sbjct: 390 RKQEEQMGE----QKEQMGEQ-----KEQMREQEEQMGE----QKEQMRKQEEHMGEQK 435
Score = 49.3 bits (116), Expect = 1e-05
Identities = 44/170 (25%), Positives = 89/170 (52%), Gaps = 32/170 (18%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDL--EEEEYLGKEE---- 78
+ + +KE TE E ++ Q+E E + E +E + E+E+ E+EE +GK+E
Sbjct: 276 EQMLKQKEQTEQE-EQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMW 334
Query: 79 ------------YLKEEEYLGK-EEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEE 125
K+EE +G+ EE ++++E E+ EE+ +EE+ +E + ++
Sbjct: 335 EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE--EQVRKQEEQMRKQEEQMRKQEEQMRKQ 392
Query: 126 EYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLG--KKAYLEEEEYLGKK 173
E E+ E++E +G+ +KE E+ + +G K+ ++EE++G++
Sbjct: 393 E----EQMGEQKEQMGE----QKEQMREQEEQMGEQKEQMRKQEEHMGEQ 434
Score = 42.0 bits (97), Expect = 0.002
Identities = 48/219 (21%), Positives = 100/219 (45%), Gaps = 27/219 (12%)
Query: 30 EKEDTEVELDEESLQ-----DESPFSPEGESLEDKEYLEEEEDL----------EEEEYL 74
E E +E++L + L+ D+ P EG+ E + + E+E +E +
Sbjct: 24 ETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 83
Query: 75 GKEEYLKEEEYLGKEEH----LEEEEYLEKAGYLEEEE-YIEEEE--YLGKEGYLEEEEY 127
+E ++E+E +E+ +E + E+ G + E+E + E+E +EG + E+E
Sbjct: 84 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 143
Query: 128 LGKEEHLEEEEYLGK----EGYL-EKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKAL 182
+E+ + E G+ EG + E+E + E + ++ + E G+ E +
Sbjct: 144 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGE 203
Query: 183 EKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQ 221
++E+ E+EE ++K+E G++ + +E Q
Sbjct: 204 QEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQ 242
Score = 40.8 bits (94), Expect = 0.004
Identities = 38/153 (24%), Positives = 81/153 (52%), Gaps = 11/153 (7%)
Query: 52 EGESLEDKEYLEEEE-DLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYI 110
EG+ E + + E+E + E+E +E+ + E G+ E + ++ E+E +
Sbjct: 100 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 159
Query: 111 EEEE--YLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYI-EEVDYLG--KKAYLE 165
E+E +EG + E+E +E+ + E G+ G E+E + E+ + +G ++ +
Sbjct: 160 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMG--EQEGQMGEQEEQMGEQEEQMQK 217
Query: 166 EEEYLGKKSYLEEEKALEKEENLEEEEALEKEE 198
+EE +G++ EE+ ++E+ E+EE ++K+E
Sbjct: 218 QEEQMGEQ---EEQMRKQEEQMGEQEEQVQKQE 247
Score = 40.0 bits (92), Expect = 0.007
Identities = 44/196 (22%), Positives = 101/196 (51%), Gaps = 22/196 (11%)
Query: 52 EGESLEDKEYLEEEE-DLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYI 110
EG+ E + + E+E + E+E +E+ + E G+ E + ++ E+E +
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
Query: 111 EEEE--------YLG-KEGYL-EEEEYLGKEEH--LEEEEYLG-KEGYLEKEDYIEEVDY 157
E+E +G +EG + E+EE +G++E ++EE +G +E + K++ E++
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE--EQMGE 238
Query: 158 LGKKAYLEEEEYLGKKSYL--EEEKALEKEENL--EEEEALEKEENLDGKENL--YKKYL 211
++ +EE+ ++ + +EE+ E+EE + +EE+ L+++E + +E ++ +
Sbjct: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298
Query: 212 KEPKASYSSQTMLLRD 227
+E + Q +R+
Sbjct: 299 REQEEQMREQEEQMRE 314
>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 432
Score = 60.8 bits (146), Expect = 4e-09
Identities = 61/217 (28%), Positives = 102/217 (47%), Gaps = 31/217 (14%)
Query: 6 NQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEE 65
NQ + P PP P + L E EL+ Q ++ +E+ + L
Sbjct: 142 NQTAEPLAPEPPAGPS-KVEQLQDETNHLRKELESVGRQLQA-------EVENNQMLSLL 193
Query: 66 EDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYL--EEEEYIEEEEYLGKEGYLE 123
+EE +EE L+E+E + H +EE E+ L +EE E+E+ G+E LE
Sbjct: 194 NRRQEERLREQEERLREQE---ERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLE 250
Query: 124 EEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALE 183
E E L ++E +EE+ E LE+E ++EV EE L ++ ++++ L
Sbjct: 251 EVEKLLEQERRQEEQ----ERLLERERLLDEV-----------EELLEQERLRQQDERLW 295
Query: 184 KEENLEEEEALEKEENL--DGKENLYKKYLKEPKASY 218
++E L E E L + E + G E LY++ EP++ +
Sbjct: 296 QQETLRELERLRELERMLELGWEALYEQ-RAEPRSGF 331
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 59.3 bits (142), Expect = 1e-08
Identities = 58/148 (39%), Positives = 77/148 (52%), Gaps = 23/148 (15%)
Query: 63 EEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYL 122
EEEE+ EEEE +EEE G+EE E EE EEEE E EE LG+E +
Sbjct: 406 EEEEEEEEEE--------EEEEGEGEEEEEEGEE--------EEEEGGEGEE-LGEEEEV 448
Query: 123 EEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKK--AY-LEEEEYLGKKSYLE-- 177
EEE + +E EE+E EG LE ED+ + V G AY +EE +LE
Sbjct: 449 EEEGDVDSDEEEEEDEESSSEG-LEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGG 507
Query: 178 EEKALEKEENLEEEEALEKEENLDGKEN 205
E+ + EE +EEE E E++ D +E+
Sbjct: 508 EDSDSDSEEEDDEEEDDEDEDDDDDEED 535
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/138 (34%), Positives = 69/138 (50%), Gaps = 18/138 (13%)
Query: 24 TQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEE 83
T +L SE E+ E E +EE ++ EGE E++ EEEE E EE LG+EE ++EE
Sbjct: 398 TTSLKSEGEEEEEEEEEEEEEEG-----EGEEEEEEGEEEEEEGGEGEE-LGEEEEVEEE 451
Query: 84 EYLGKEEHLEEEEYLEKAGYLEEEEY----IEEEEYLGKEGYLEEEE-----YL--GKEE 132
+ +E EE+E G LE E++ +E G G EE + +L G++
Sbjct: 452 GDVDSDEEEEEDEESSSEG-LEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDS 510
Query: 133 HLEEEEYLGKEGYLEKED 150
+ EE +E E ED
Sbjct: 511 DSDSEEEDDEEEDDEDED 528
Score = 39.7 bits (91), Expect = 0.010
Identities = 40/134 (29%), Positives = 60/134 (44%), Gaps = 6/134 (4%)
Query: 10 GASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLE 69
G P TT S E+E+ E E + E ++E E E + E L EEE++E
Sbjct: 390 GGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVE 449
Query: 70 EEEYLGKEEYLKEEEYLGKEEHLEEEEYLE---KAGYLEEEEYIEEEEYLGKEGYLE--E 124
EE + +E +EE+ E LE E++ + +AG +EE +LE E
Sbjct: 450 EEGDVDSDEE-EEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGE 508
Query: 125 EEYLGKEEHLEEEE 138
+ EE +EEE
Sbjct: 509 DSDSDSEEEDDEEE 522
Score = 37.7 bits (86), Expect = 0.036
Identities = 32/82 (39%), Positives = 43/82 (52%), Gaps = 13/82 (15%)
Query: 116 LGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSY 175
L EG EEEE EE EEEE G+E E+E+ EE + G E E LG++
Sbjct: 401 LKSEGEEEEEE----EEEEEEEEGEGEE---EEEEGEEEEEEGG------EGEELGEEEE 447
Query: 176 LEEEKALEKEENLEEEEALEKE 197
+EEE ++ +E EE+E E
Sbjct: 448 VEEEGDVDSDEEEEEDEESSSE 469
Score = 32.3 bits (72), Expect = 1.5
Identities = 27/65 (41%), Positives = 38/65 (58%), Gaps = 7/65 (10%)
Query: 140 LGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEEN 199
L EG E+E+ EE + G+ EEEE G++ EEE+ E EE L EEE +E+E +
Sbjct: 401 LKSEGEEEEEEEEEEEEEEGEG---EEEEEEGEE---EEEEGGEGEE-LGEEEEVEEEGD 453
Query: 200 LDGKE 204
+D E
Sbjct: 454 VDSDE 458
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 58.9 bits (141), Expect = 2e-08
Identities = 69/247 (27%), Positives = 110/247 (44%), Gaps = 18/247 (7%)
Query: 59 KEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGK 118
K+ L E + EEE+L K+ E G E E +K ++EE IE+E L K
Sbjct: 763 KKQLALNETINEEEFLNKQPLALE----GYPSIAEGETLFKKLLAMQEEPSIEKEAVL-K 817
Query: 119 EGYLEEEEYLGKEEHLEEEEYLGKEGYLEK-----EDYIEEVDYLGKKAYLEEEEYLGKK 173
E ++ E + + L+EE KE L++ E + +E L +K +E+E +
Sbjct: 818 EPTIDTEAHFKEPLALQEEPSTEKEAVLKEPSVDTEAHFKETLALQEKPSIEQEALFKRH 877
Query: 174 SYLEEEKALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDA 233
S L E+ + EKE +E L+++ ++ KE L KK L K S ++ +L D + +
Sbjct: 878 SALWEKPSTEKETIFKESLDLQEKPSIK-KETLLKKPL-ALKMSTINEAVLFEDMIALNE 935
Query: 234 GPSQVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKS 293
P+ L+F P + ES T + L Q T TA +S+ SKS
Sbjct: 936 KPT-----TGKELSFKEPLALQESPTYKEDTFLKTLLVPQVG-TSPNVSSTAPESITSKS 989
Query: 294 ETEQETT 300
T+
Sbjct: 990 SIATMTS 996
Score = 50.1 bits (118), Expect = 7e-06
Identities = 38/137 (27%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Query: 76 KEEYLKEEEYLGKEEHLEEEEY-LEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHL 134
+E++L +E KE+H +E L K +E+ EEE+ +E + ++ K L
Sbjct: 631 EEKFLSQEPSALKEKHTTLQEVSLSKESLAIQEKATTEEEF-SQELFSLHVKHTNKSGSL 689
Query: 135 EEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEAL 194
+E + +E +ED ++ + L +K+ +EEE + K L+EE + E N++ + +L
Sbjct: 690 FQEALVLQEKTDAEEDSLKNLLALQEKSTMEEESLINKLLALKEELSAEAATNIQTQLSL 749
Query: 195 EKEENLDGKENLYKKYL 211
+K+ GK KK L
Sbjct: 750 KKKSTSHGKVFFLKKQL 766
Score = 48.1 bits (113), Expect = 3e-05
Identities = 60/243 (24%), Positives = 105/243 (43%), Gaps = 9/243 (3%)
Query: 29 SEKEDTEVELDEESLQDES-PFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLG 87
+E + E L+++ L E P EGE+L K +EE E+E + KE + E +
Sbjct: 769 NETINEEEFLNKQPLALEGYPSIAEGETLFKKLLAMQEEPSIEKEAVLKEPTIDTEAHFK 828
Query: 88 KEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLE 147
+ L+EE EK L+E ++ E + + L+E+ + +E + L ++ E
Sbjct: 829 EPLALQEEPSTEKEAVLKEPS-VDTEAHFKETLALQEKPSIEQEALFKRHSALWEKPSTE 887
Query: 148 KEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLY 207
KE +E L +K +++E L K L + + E L E+ E+ GKE +
Sbjct: 888 KETIFKESLDLQEKPSIKKETLL--KKPLALKMSTINEAVLFEDMIALNEKPTTGKELSF 945
Query: 208 KKYLKEPKASYSSQTMLLRDARSPDAG-----PSQVTTFLTVPLTFATPSPVSESATESS 262
K+ L ++ + L+ P G S +T + AT + V +S T +
Sbjct: 946 KEPLALQESPTYKEDTFLKTLLVPQVGTSPNVSSTAPESITSKSSIATMTSVGKSGTINE 1005
Query: 263 ELL 265
L
Sbjct: 1006 AFL 1008
Score = 43.1 bits (100), Expect = 9e-04
Identities = 61/287 (21%), Positives = 122/287 (42%), Gaps = 23/287 (8%)
Query: 40 EESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYL- 98
EE++ ++ S + + + + ++ L ++ +EE ++ K + EE++L
Sbjct: 577 EETVLTKTSLSLQEKKITQGKMSHLKKPLVLQKITSEEESFYKKLLPFKMKSTTEEKFLS 636
Query: 99 EKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYL 158
++ L+E+ +E L KE +E+ +EE +E L + + +E L
Sbjct: 637 QEPSALKEKHTTLQEVSLSKESLAIQEKATTEEEFSQELFSLHVKHTNKSGSLFQEALVL 696
Query: 159 GKKAYLEEEEY-----LGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYKKYLKE 213
+K EE+ L +KS +EEE + K L+EE + E N+ + +L KK
Sbjct: 697 QEKTDAEEDSLKNLLALQEKSTMEEESLINKLLALKEELSAEAATNIQTQLSLKKKSTSH 756
Query: 214 PKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQ 273
K + + + L + + + F P++ S TL+++
Sbjct: 757 GKVFFLKKQLALNETINEE--------------EFLNKQPLALEGYPSIAEGETLFKKLL 802
Query: 274 ASQTDWCYDRTAVKSLKSKS-ETEQETTTKLAPEEHVNTKVQQKKEE 319
A Q + ++ AV LK + +TE LA +E +T+ + +E
Sbjct: 803 AMQEEPSIEKEAV--LKEPTIDTEAHFKEPLALQEEPSTEKEAVLKE 847
Score = 36.6 bits (83), Expect = 0.081
Identities = 56/256 (21%), Positives = 107/256 (41%), Gaps = 28/256 (10%)
Query: 88 KEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLE 147
K + EE K L+EE IE+E + K L++ + LE+ + L +E +
Sbjct: 144 KTPNTEEASLFRKPLVLKEEPTIEDETLINKSLSLKKCSNHEEVSLLEKLQPLQEESDSD 203
Query: 148 KEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEK--ALEKEENLEEEEALEKEENLDGKEN 205
IE + + KK + EE + KK+ ++K A +++++ +EE ++ N++
Sbjct: 204 DAFVIEPMTF--KKTHKTEEAAITKKTLSLKKKMCASQRKQSCQEESLAVQDVNMEEDSF 261
Query: 206 LYK--KYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFAT--------PSPVS 255
+ + K+PK S T L + ++ F P+ T P +
Sbjct: 262 FMESMSFKKKPKTEESIPTHKLSSLKKKCTIYGKICHFRKPPVLQTTICGAMSSIKKPTT 321
Query: 256 ESATESSELL-----------LTLYRRSQASQ-TDWCYDRTAVKSL--KSKSETEQETTT 301
E T EL +++ ++S A Q T++ D +SL K K TE+
Sbjct: 322 EKETLFQELSVLQEKHTTEHEMSILKKSLALQKTNFKEDSLVKESLAFKKKPSTEEAIMM 381
Query: 302 KLAPEEHVNTKVQQKK 317
+ +E T+ ++ +
Sbjct: 382 PVILKEQCMTEGKRSR 397
Score = 31.6 bits (70), Expect = 2.6
Identities = 68/335 (20%), Positives = 123/335 (36%), Gaps = 41/335 (12%)
Query: 128 LGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEEN 187
L +E +E+E + K L+K EEV L K L+EE +++ E +K
Sbjct: 160 LKEEPTIEDETLINKSLSLKKCSNHEEVSLLEKLQPLQEESD-SDDAFVIEPMTFKKTHK 218
Query: 188 LEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLT 247
EE +K +L K + K S +++ ++D + +F ++
Sbjct: 219 TEEAAITKKTLSLK-----KKMCASQRKQSCQEESLAVQDVNMEE------DSFFMESMS 267
Query: 248 FATPSPVSES----ATESSELLLTLY------RRSQASQTDWCYDRTAVKSLKSKSETEQ 297
F ES S + T+Y R+ QT C +++K ++ ET
Sbjct: 268 FKKKPKTEESIPTHKLSSLKKKCTIYGKICHFRKPPVLQTTICGAMSSIKKPTTEKETLF 327
Query: 298 ETTTKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQ 357
+ + L + ++ K+ L+ K NF + D L E L S+ +
Sbjct: 328 QELSVLQEKHTTEHEMSILKKSLALQ---KTNFKE-------DSLVKESLAFKKKPSTEE 377
Query: 358 TVFKTIIKEMAAHNELEEDFDIPLTKLLESENRWKLVIML--------KKNYEKFKETIL 409
+ +I + E + PL L E + K +IM E F +
Sbjct: 378 AIMMPVILKEQCMTEGKRSRLKPLV-LQEITSGEKSLIMKPLSIKEKPSTEKESFSQEPS 436
Query: 410 RIKRRREAQKLTEMTSFTFHLMSKPTPEKPETEEI 444
++++ Q+ + L+ PT E P E +
Sbjct: 437 ALQKKHTTQEEVSILKEPSSLLKSPTEESPFDEAL 471
Score = 31.2 bits (69), Expect = 3.4
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 8/142 (5%)
Query: 59 KEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGK 118
K+ E+E L +E + +E++ E E L++ L+K + +E+ ++E K
Sbjct: 317 KKPTTEKETLFQELSVLQEKHTTEHEM----SILKKSLALQKTNF-KEDSLVKESLAFKK 371
Query: 119 EGYLEEEEYLG---KEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSY 175
+ EE + KE+ + E + + + +E E + K ++E+ K+S+
Sbjct: 372 KPSTEEAIMMPVILKEQCMTEGKRSRLKPLVLQEITSGEKSLIMKPLSIKEKPSTEKESF 431
Query: 176 LEEEKALEKEENLEEEEALEKE 197
+E AL+K+ +EE ++ KE
Sbjct: 432 SQEPSALQKKHTTQEEVSILKE 453
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 58.2 bits (139), Expect = 3e-08
Identities = 114/488 (23%), Positives = 193/488 (39%), Gaps = 63/488 (12%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEY---- 85
E+E+ L E + + E LE++E ++ LE+ K + L+EE+
Sbjct: 926 EEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILED 985
Query: 86 ----LGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLG 141
L KE+ L E+ E L EEE E+ + L K E EE L EE
Sbjct: 986 QNCKLAKEKKLLEDRIAEFTTNLTEEE--EKSKSLAKLKNKHEAMITDLEERLRREEKQR 1043
Query: 142 KEGYLEK------------EDYIEE----VDYLGKKAYLEEEEYLGKKSYLEEE-----K 180
+E LEK D I E + L + +EEE + +EEE
Sbjct: 1044 QE--LEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNM 1101
Query: 181 ALEKEENLEE-----EEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGP 235
AL+K LE +E LE E K K+ L E + ++ L D A
Sbjct: 1102 ALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTE---LEDTLDSTAAQ 1158
Query: 236 SQVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQ--TDWCYDRTAVK-SLKSK 292
++ + + + E+ T +++ + SQA + + VK +L+
Sbjct: 1159 QELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKA 1218
Query: 293 SETEQETTTKLAPE-----------EHVNTKVQQKKEENVLEFASKENFWDGITDESIDK 341
+T + +LA E EH KV+ + +E ++F E + D+ + K
Sbjct: 1219 KQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK-VTK 1277
Query: 342 LEVEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDFDIPLTKLLESENRWKLVIMLK-KN 400
L+VE + L S + + K+ +A +D +LL+ ENR KL + K K
Sbjct: 1278 LQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQD----TQELLQEENRQKLSLSTKLKQ 1333
Query: 401 YEKFKETIL-RIKRRREAQKLTEMTSFTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLER 459
E K + +++ EA+ E T H +K E + + + ++KL++
Sbjct: 1334 VEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQK 1392
Query: 460 DKEWIQKK 467
D E + ++
Sbjct: 1393 DLEGLSQR 1400
Score = 51.6 bits (122), Expect = 2e-06
Identities = 89/393 (22%), Positives = 152/393 (38%), Gaps = 37/393 (9%)
Query: 42 SLQDESPFSPEGESLEDKE-YLEEEEDLEEEEYLGKE---EYLKEEEYLGKEEHLEEEEY 97
S Q+E + E E ++ +E L E L E E L + E L+ +E L E L E
Sbjct: 841 SRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAE 900
Query: 98 LEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDY 157
+A +++ +EE + E +EEEE + +HL+ E+ ++ E E+ +EE +
Sbjct: 901 ELRARLTAKKQELEEICH-DLEARVEEEEE--RCQHLQAEKKKMQQNIQELEEQLEEEES 957
Query: 158 LGKKAYLEEEEYLGKKSYLEEEKALEKEEN---------------------LEEEEALEK 196
+K LE+ K LEEE+ + +++N EEEE +
Sbjct: 958 ARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS 1017
Query: 197 EENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSE 256
L K L+E Q L R G S + L +
Sbjct: 1018 LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ 1077
Query: 257 SATESSELLLTLYR-RSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQ 315
A + EL L R +A+Q + A+K ++ E L E K ++
Sbjct: 1078 LAKKEEELQAALARVEEEAAQKN-----MALKKIRELESQISELQEDLESERASRNKAEK 1132
Query: 316 KKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNELEE 375
+K + E + + + D + + E+ E +N +T+ + A E+ +
Sbjct: 1133 QKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ 1192
Query: 376 DFDIPLTKLLESENRWKLVIMLKKNYEKFKETI 408
+ +L E + K V K N EK K+T+
Sbjct: 1193 KHSQAVEELAEQLEQTKRV---KANLEKAKQTL 1222
Score = 42.0 bits (97), Expect = 0.002
Identities = 85/428 (19%), Positives = 162/428 (37%), Gaps = 45/428 (10%)
Query: 67 DLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEE 126
D + + E+ K+ + L EE +Y E+ E E +E + L LEE
Sbjct: 1430 DHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Query: 127 YLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKA----L 182
E E E L K+ E ED + D +GK + E+ + +EE K L
Sbjct: 1490 -----EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEEL 1544
Query: 183 EKEENLEEEEALEKEENLDGKENLYKKYLK-EPKASYSSQTMLLRDARSPDAGPSQ---- 237
E E E+ L E NL + +++ L+ + S + L+R R +A
Sbjct: 1545 EDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQ 1604
Query: 238 ----VTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYD----------- 282
V + + +SA ++ + + R+ QA D +
Sbjct: 1605 RSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEI 1664
Query: 283 ----RTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDES 338
+ K LKS + +LA E + QQ+++E E A+ +E
Sbjct: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK 1724
Query: 339 ------IDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDFDIPLTKLLESENRWK 392
I +LE E+L+E N+ + + + K +++ D ++ + ++EN +
Sbjct: 1725 RRLEARIAQLE-EELEEEQGNT--ELINDRLKKANLQIDQINTDLNLERSHAQKNENARQ 1781
Query: 393 LVIMLKKNYEKFKETILRIKRRREAQKLTEMTSFTFHLMSKPTPEKPETEEIQKPQRVVH 452
L++ ++ K + ++ +++ +T+ + ET+E Q + V
Sbjct: 1782 ---QLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVR 1838
Query: 453 HRKKLERD 460
+K +D
Sbjct: 1839 RTEKKLKD 1846
Score = 39.7 bits (91), Expect = 0.010
Identities = 84/421 (19%), Positives = 174/421 (41%), Gaps = 53/421 (12%)
Query: 27 LPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYL 86
L S+ +DT+ L EE+ Q S S + + +ED++ E+ EEEE K K+ L
Sbjct: 1306 LESQLQDTQELLQEENRQKLS-LSTKLKQVEDEKNSFREQLEEEEE--AKHNLEKQIATL 1362
Query: 87 GKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLE-EEEYLGKEEHLEEEEYLGKEGY 145
+ +++ + G LE E ++ + EG + EE + + LE+ + ++
Sbjct: 1363 HAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQ-- 1420
Query: 146 LEKEDYIEEVDYLGKKA------------YLEEEEYLGKKSYLEEEKALEKEENLEEEEA 193
E +D + ++D+ + A L EE+ + K Y EE E E +E +A
Sbjct: 1421 -ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAK-YAEERDRAEAEAREKETKA 1478
Query: 194 LE----KEENLDGK---ENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPL 246
L EE ++ K E L K++ E + SS+ + + + + +
Sbjct: 1479 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK 1538
Query: 247 TFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPE 306
T ATE ++L L + ++ +Q + + L+ + E +E +L +
Sbjct: 1539 TQLEELEDELQATEDAKLRLEVNLQAMKAQFE--------RDLQGRDEQSEEKKKQLVRQ 1590
Query: 307 -EHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENF--LNSSYQTVFKTI 363
+ +++ ++++ + A+++ +++++DL+ + N + K +
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKL----------EMDLKDLEAHIDSANKNRDEAIKQL 1640
Query: 364 IKEMAAHNELEEDFDIPLTKLLE-----SENRWKLVIMLKKNYEKFKETILRIKRRREAQ 418
K A + + D E EN KL M + + +E + +R+AQ
Sbjct: 1641 RKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQ 1700
Query: 419 K 419
+
Sbjct: 1701 Q 1701
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 58.2 bits (139), Expect = 3e-08
Identities = 43/168 (25%), Positives = 88/168 (52%), Gaps = 9/168 (5%)
Query: 57 EDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYL 116
E++ E E+ + EEE + +E+ K +E K EE+ + ++ E+EE + E+E
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE-- 60
Query: 117 GKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYI-EEVDYLGKKAYLEEEEYLGKKSY 175
E E+EE + +++ L E+ KE E+++ + E+ + + ++ ++ E + +K
Sbjct: 61 --EKMWEQEEKMWEQQRLPEQ----KEKMWEQDERLREKEERMREQKMWQQVEKMREKKK 114
Query: 176 LEEEKALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTM 223
+EEK E+EE ++E+E + E+ +E K + +E K + M
Sbjct: 115 TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 162
Score = 55.1 bits (131), Expect = 2e-07
Identities = 49/188 (26%), Positives = 105/188 (55%), Gaps = 16/188 (8%)
Query: 44 QDESPFSPEGESLEDKEYL-EEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAG 102
++E E + E++E + E+EE ++E+E +E+ EE+ +EE ++E+E EK
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ---EEKMWEQEEKMQEQE--EKM- 56
Query: 103 YLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLG-KEGYLEKEDYIEEVDYLGKK 161
+ +EE+ E+EE + ++ L E+ KE+ E++E L KE + ++ ++V+ + +K
Sbjct: 57 WEQEEKMWEQEEKMWEQQRLPEQ----KEKMWEQDERLREKEERMREQKMWQQVEKMREK 112
Query: 162 AYLEEEEYLGKKSYLEEEKAL--EKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYS 219
+EE+ ++ ++E++ + E+EE ++E+E EK + K ++ ++E +
Sbjct: 113 KKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQE--EKMWEQEEKMREQEEKMREQEEKMQ 170
Query: 220 SQTMLLRD 227
Q +RD
Sbjct: 171 GQEEKMRD 178
Score = 55.1 bits (131), Expect = 2e-07
Identities = 46/179 (25%), Positives = 95/179 (53%), Gaps = 18/179 (10%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKE--YLEEEEDLEEEEYLGKEEYLKEEEYLG 87
E+E E +E + E + E + ++E E+EE ++E+E ++ + +EE+
Sbjct: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE---EKMWEQEEKMWE 65
Query: 88 KEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLE 147
+EE + E++ L + +E+ + ++E KE + E++ + E + E++ +E E
Sbjct: 66 QEEKMWEQQRLPEQ---KEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQE 122
Query: 148 KEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENL--EEEEALEKEENLDGKE 204
+E+ ++E + + E+EE K +EEK E+EE + +EE+ E+EE + G+E
Sbjct: 123 QEEKMQEQEEM----MWEQEE----KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 173
Score = 43.9 bits (102), Expect = 5e-04
Identities = 36/127 (28%), Positives = 64/127 (50%), Gaps = 17/127 (13%)
Query: 22 YSTQNLPSEKE-----DTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGK 76
+ Q LP +KE D + EE ++++ + + E K+ EE+ +EE+ +
Sbjct: 71 WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQ 130
Query: 77 EEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEE 136
EE + E+E E+ E+EE + E+EE + E+E +E +EE+ G+EE + +
Sbjct: 131 EEMMWEQE----EKMQEQEEKM-----WEQEEKMREQEEKMRE---QEEKMQGQEEKMRD 178
Query: 137 EEYLGKE 143
E G E
Sbjct: 179 VEPAGGE 185
Score = 37.4 bits (85), Expect = 0.047
Identities = 46/199 (23%), Positives = 87/199 (43%), Gaps = 51/199 (25%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKE---YLEEEEDLEEEEYLGKEEYLK 81
+ + E+E+ E +E+ + E + E ++++E + +EE+ E+EE + +++ L
Sbjct: 18 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 77
Query: 82 E---------EEYLGKEEHLEE-------EEYLEKAGYLEEEEYIEEEEYLGKEGYLEEE 125
E E KEE + E E+ EK EE+ +EE+ +E + E+
Sbjct: 78 EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQ 137
Query: 126 EYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKE 185
EE ++E+E E E+E+ + E +EEK E+E
Sbjct: 138 -----EEKMQEQE----EKMWEQEEKMRE----------------------QEEKMREQE 166
Query: 186 ENLE-EEEALEKEENLDGK 203
E ++ +EE + E G+
Sbjct: 167 EKMQGQEEKMRDVEPAGGE 185
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 57.8 bits (138), Expect = 3e-08
Identities = 67/216 (31%), Positives = 101/216 (46%), Gaps = 25/216 (11%)
Query: 6 NQLSGASPPHPPTTP------QYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDK 59
NQ + P PP P Q T +L E E +L E +++ S E++
Sbjct: 142 NQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAE-VENNQMLSLLNRRQEER 200
Query: 60 EYLEEEEDLEEEEYLGKEEYL---KEEEYLGKEEHLEEEEYL----EKAGYLEEEEYIEE 112
+EE E+EE L ++E +EE +EE L E+E E+ + +EE E+
Sbjct: 201 LREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQ 260
Query: 113 EEYL-GKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLG 171
EE L +E L E+E L +E L EE E LE+E EE + L LE E L
Sbjct: 261 EERLCEQEERLCEQEKLPGQERLLEE----VEKLLEQERRQEEQERL-----LERERLLD 311
Query: 172 K-KSYLEEEKALEKEENLEEEEALEKEENLDGKENL 206
+ + LE+E+ +++E L ++E L + E L E L
Sbjct: 312 EVEELLEQERLRQQDERLWQQETLRELERLRELERL 347
Score = 47.4 bits (111), Expect = 5e-05
Identities = 54/190 (28%), Positives = 90/190 (47%), Gaps = 31/190 (16%)
Query: 44 QDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKE--EHLEEEEYLEKA 101
Q P +PE + K E L++E KE E +G++ +E + L
Sbjct: 143 QTAEPLAPEPPAGPSKV-----EQLQDET----NHLRKELESVGRQLQAEVENNQMLSLL 193
Query: 102 GYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKK 161
+EE E+EE L ++ EE +EE L E+E E E+E+ + E + +
Sbjct: 194 NRRQEERLREQEERLHEQ----EERLHEQEERLCEQE----ERLCEQEERLREQE----E 241
Query: 162 AYLEEEEYLGKKSYLEEEKALEKEENL-EEEEALEKEENLDGKENL---YKKYLKEPKAS 217
E+EE L + +EE+ E+EE L E+EE L ++E L G+E L +K L++ +
Sbjct: 242 RLREQEERLHE----QEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQ 297
Query: 218 YSSQTMLLRD 227
+ +L R+
Sbjct: 298 EEQERLLERE 307
Score = 38.1 bits (87), Expect = 0.028
Identities = 44/142 (30%), Positives = 68/142 (47%), Gaps = 21/142 (14%)
Query: 25 QNLPSEK---EDTEVELDEESLQDESPFSPEGESLEDK--EYLEEEEDLEEEEYLGKEEY 79
+ LP ++ E+ E L++E Q+E E E L D+ E LE+E +++E L ++E
Sbjct: 275 EKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQET 334
Query: 80 LKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEE--EEYLGKEEHLEEE 137
L+E E L + E L E E L E E +E LG E E+ E G EE E
Sbjct: 335 LRELERLRELERLRELERLR-----ELERMLE----LGWEALYEQRAEPRSGFEELNNE- 384
Query: 138 EYLGKEGYLEKEDYIEEVDYLG 159
+ L+ E ++E++ G
Sbjct: 385 ----NKSTLQLEQQVKELEKSG 402
Score = 29.6 bits (65), Expect = 9.9
Identities = 34/128 (26%), Positives = 61/128 (47%), Gaps = 11/128 (8%)
Query: 88 KEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKE---GYLEEEEYLGKEEHLEEE-EYLGKE 143
KEE E ++K G + + E L E G + E+ + HL +E E +G++
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 144 --GYLEKEDYIEEVDYLGKKAYLEEEEYLGKKS---YLEEEKALEKEENL--EEEEALEK 196
+E + ++ ++ E+EE L ++ + +EE+ E+EE L +EE E+
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQ 239
Query: 197 EENLDGKE 204
EE L +E
Sbjct: 240 EERLREQE 247
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 57.4 bits (137), Expect = 4e-08
Identities = 91/367 (24%), Positives = 159/367 (43%), Gaps = 56/367 (15%)
Query: 16 PPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESL-----EDKEYLEEEEDLEE 70
P P+ + +P EK+ T V E+ + P E + +++E L EEE + E
Sbjct: 10057 PAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPE 10116
Query: 71 EEYLGKEEYL--KEEEYLGKEEH-LEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEY 127
EE L +EE + +EEE L +EE L EEE + EEEE EEEY+ EEEE+
Sbjct: 10117 EEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPP----EEEEVPPEEEYVP-----EEEEF 10167
Query: 128 LGKEEHLEEEEYLG---------KEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYL-- 176
+ +EE L E + K+ EK+ I + + E + + +K +
Sbjct: 10168 VPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILP 10227
Query: 177 EEEKAL-------EKEENLEEEEALEKEENLDGKENLYKKYLKE--PKASYSSQTMLLRD 227
+EE+ L +EE + EEE E+ +++ E + + E KA + T + +
Sbjct: 10228 KEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKK 10287
Query: 228 ARSPDAGPSQVTTFLTVPLTF----ATPSPVSESATESSELLLTLYRRSQASQTDWCYDR 283
+P A S+ VP+ A P+ V E + E + + ++
Sbjct: 10288 VEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKE----------- 10336
Query: 284 TAVKSLKSKSETEQETTTKLAPEEHVNTKVQ-QKKEENVLEFASKENFWDGITDESIDKL 342
AV K ++ E++ + E V +++ + E V E +E F + +E ++
Sbjct: 10337 -AVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHE--VEEYFEEG 10393
Query: 343 EVEDLDE 349
E +++E
Sbjct: 10394 EFHEVEE 10400
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/101 (36%), Positives = 49/101 (48%), Gaps = 16/101 (15%)
Query: 40 EESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLE 99
EE + E+P E + +++ +EE+E Y EEE + + E EEY E
Sbjct: 9702 EEKVSIEAP-KREPQPIKEVTIMEEKE----------RAYTLEEEAVSVQREEEYEEY-E 9749
Query: 100 KAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYL 140
+ Y E EEY EEY E Y EE EY EEH EEY+
Sbjct: 9750 EYDYKEFEEYEPTEEYDQYEEY-EEREYERYEEH---EEYI 9786
Score = 42.0 bits (97), Expect = 0.002
Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 13/133 (9%)
Query: 27 LPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYL 86
+P E + E L+ + P + E ++ + +EE + E + + +KE +
Sbjct: 9664 VPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIM 9723
Query: 87 GKEEH---LEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGK- 142
++E LEEE EEEY E EEY Y E EEY EE+ + EEY +
Sbjct: 9724 EEKERAYTLEEEA----VSVQREEEYEEYEEY----DYKEFEEYEPTEEYDQYEEYEERE 9775
Query: 143 -EGYLEKEDYIEE 154
E Y E E+YI E
Sbjct: 9776 YERYEEHEEYITE 9788
Score = 40.0 bits (92), Expect = 0.007
Identities = 43/140 (30%), Positives = 63/140 (45%), Gaps = 13/140 (9%)
Query: 41 ESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEK 100
E DE P E E Y E +ED EE + K+E +E E E+ E +EY E+
Sbjct: 9074 EEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWE----EDFEEGQEYYER 9129
Query: 101 AGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGK 160
EE Y E EE +E Y +E E + ++ + EE + K E + K
Sbjct: 9130 -----EEGYDEGEEE-WEEAY-QEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIK 9182
Query: 161 KAYLEEEEYLGKKSYLEEEK 180
K +E+ E ++ +EEEK
Sbjct: 9183 KPVIEKIEKTSRR--MEEEK 9200
Score = 39.3 bits (90), Expect = 0.012
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 14/145 (9%)
Query: 13 PPHPPTTPQYSTQNLPSEKEDTEVELDE----------ESLQDESPFSPEGESL---EDK 59
P P ++ +P EK V+ E + + ++ P+ E++ + +
Sbjct: 10285 PKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGR 10344
Query: 60 EYLEEEEDLE-EEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGK 118
LEE+ + +E + KE E EE EEEE+ E Y EE E+ E EE++
Sbjct: 10345 TVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKL 10404
Query: 119 EGYLEEEEYLGKEEHLEEEEYLGKE 143
E + EEE+ ++ H E + +E
Sbjct: 10405 EQHRVEEEHRVEKVHRVIEVFEAEE 10429
Score = 38.9 bits (89), Expect = 0.016
Identities = 50/207 (24%), Positives = 89/207 (42%), Gaps = 15/207 (7%)
Query: 13 PPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYL---EEEEDLE 69
P PP P+ + +P EK V +E+ + P +G E+K + EE
Sbjct: 9338 PAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPP 9397
Query: 70 EEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYL----GKEGYLEEE 125
+ K++ +E + + ++E EE K L ++ EE+ + K+
Sbjct: 9398 AVPEIPKKKVPEERKPVPRKE--EEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRA 9455
Query: 126 EYLGKEEHLEEEEYLGKEGYL-----EKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEK 180
E + K+ +EE+ ++ +E E EV + +Y EEEE + Y EEE+
Sbjct: 9456 E-VSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEER 9514
Query: 181 ALEKEENLEEEEALEKEENLDGKENLY 207
E+E + E E +E+ E +E L+
Sbjct: 9515 EEEEEAEVTEYEVMEEPEEYVVEEKLH 9541
Score = 38.9 bits (89), Expect = 0.016
Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 8/80 (10%)
Query: 35 EVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEE 94
EV + EE E ++ E E++ + EE E+ EE +Y EEY EEY EE+ EE
Sbjct: 9719 EVTIMEEK---ERAYTLEEEAVSVQRE-EEYEEYEEYDYKEFEEYEPTEEYDQYEEY-EE 9773
Query: 95 EEYLEKAGYLEEEEYIEEEE 114
EY Y E EEYI E E
Sbjct: 9774 REY---ERYEEHEEYITEPE 9790
Score = 37.0 bits (84), Expect = 0.062
Identities = 41/136 (30%), Positives = 64/136 (47%), Gaps = 17/136 (12%)
Query: 63 EEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLE--KAGYLEE--EEYIEEEEYLGK 118
E+E E+++ + KE+ + E + + LE E Y E + Y EE E+Y E + K
Sbjct: 9051 EKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKK 9110
Query: 119 EGYLE-EEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLE 177
E + E EE++ +E+ E E EGY E E+ EE AY E E +K E
Sbjct: 9111 EVHEEWEEDFEEGQEYYERE-----EGYDEGEEEWEE-------AYQEREVIQVQKEVYE 9158
Query: 178 EEKALEKEENLEEEEA 193
E + + E++A
Sbjct: 9159 ESHERKVPAKVPEKKA 9174
Score = 37.0 bits (84), Expect = 0.062
Identities = 25/63 (39%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Query: 57 EDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEH-LEEEEYLEKAGYLEEEEYIEEEEY 115
E +E EEEE E EEY + E+ + EE++ E+H +EEE +EK + E EE E
Sbjct: 10373 EVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEV 10432
Query: 116 LGK 118
K
Sbjct: 10433 FEK 10435
Score = 36.6 bits (83), Expect = 0.081
Identities = 30/119 (25%), Positives = 60/119 (50%), Gaps = 6/119 (5%)
Query: 93 EEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYI 152
++E EK E+++ + +E+ + E + E + L E + E E + Y E ++
Sbjct: 9045 KKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFE---QPYYEEPDEDY 9101
Query: 153 EEVDYLGKKAYLEE--EEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYKK 209
EE+ KK EE E++ + Y E E+ ++ E E EEA ++ E + ++ +Y++
Sbjct: 9102 EEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEE-EWEEAYQEREVIQVQKEVYEE 9159
Score = 36.2 bits (82), Expect = 0.11
Identities = 91/408 (22%), Positives = 158/408 (38%), Gaps = 63/408 (15%)
Query: 51 PEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYI 110
PE + L+ K EEE + E+ ++ +KEE+ + E E + +++ +EE+E
Sbjct: 9673 PEEKVLKLKPKREEEPPAKVTEF--RKRVVKEEK-VSIEAPKREPQPIKEVTIMEEKE-- 9727
Query: 111 EEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYL 170
Y EEE + + E EEY EE DY + Y EEY
Sbjct: 9728 --------RAYTLEEEAVSVQREEEYEEY-------------EEYDYKEFEEYEPTEEYD 9766
Query: 171 GKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARS 230
+ Y EE+ E+ E EE E E+ + K + +PKA +L+ A
Sbjct: 9767 QYEEY--EEREYERYEE-HEEYITEPEKPIPVKPVPEEPVPTKPKA---PPAKVLKKAVP 9820
Query: 231 PDAGPSQVTTFLTVPLTFATPSPVSESATE--SSELLLTLYRRSQASQTDWCYDRTAVKS 288
+ P + L P P V E + ++ +++ +R + T + A
Sbjct: 9821 EEKVPVPIPKKLKPP-----PPKVPEEPKKVFEEKIRISITKREKEQVT----EPAAKVP 9871
Query: 289 LKSKSETEQETTTKLAPEEHVNTKV---QQKKEENVLEFASKENFWDGITDESIDKLE-- 343
+K K +E P + V V + KE E A +E + + +++ E
Sbjct: 9872 MKPKRVVAEEKVP--VPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEY 9929
Query: 344 VEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYEK 403
+ + +E V + E+ EE +P+ K E+ K+ + KK EK
Sbjct: 9930 IHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPA-KVPEVPKKPEEK 9988
Query: 404 FKETILRIKRRREAQKLTEMTSFTFHLMSKPTPEK----PETEEIQKP 447
I + K + K+ E+ KP PE+ P ++++ P
Sbjct: 9989 VPVLIPK-KEKPPPAKVPEVP-------KKPVPEEKVPVPVPKKVEAP 10028
Score = 35.4 bits (80), Expect = 0.18
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 16/112 (14%)
Query: 16 PPTTPQYSTQNLPSEK-------------EDTEVELDEESLQDESPFSPEGESLEDKEYL 62
PP + S + + EK + EV E S ++E +S E E + Y
Sbjct: 9451 PPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYR 9510
Query: 63 EEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEE 114
EEE + EEE + + E ++E E EE L + K E E E +E
Sbjct: 9511 EEEREEEEEAEVTEYEVMEEPEEYVVEEKL---HIISKRVEAEPAEVTERQE 9559
Score = 31.6 bits (70), Expect = 2.6
Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 4/59 (6%)
Query: 14 PHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEE 72
P P +P E E EV +EE + + E E++EY+ EEE+ EE
Sbjct: 9886 PRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVE----EEEEYIHEEEEFITEE 9940
Score = 30.4 bits (67), Expect = 5.8
Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 10/85 (11%)
Query: 16 PPTTPQYSTQNLPSEKEDTEVELDEE--SLQDESPFSPEGESLEDKEYLEEEEDLEEEEY 73
P PQ + E+++ L+EE S+Q E + E E + KE+ EE E EEY
Sbjct: 9710 PKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYE-EYEEYDYKEF-EEYEP--TEEY 9765
Query: 74 LGKEEYLKEEEYLGKEEHLEEEEYL 98
EEY +E EY EEH EEY+
Sbjct: 9766 DQYEEY-EEREYERYEEH---EEYI 9786
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 57.4 bits (137), Expect = 4e-08
Identities = 56/218 (25%), Positives = 111/218 (50%), Gaps = 28/218 (12%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDL--EEEEYLGKEE---- 78
+ L S + +++E L + E + +E ++E E+ E+EE + ++E
Sbjct: 260 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMR 319
Query: 79 ------YLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEE 132
+ KEE+ +EE + E+E EK LEE+ + E+E+ +E +EEE + ++E
Sbjct: 320 RQEEMMWEKEEKMRRQEEMMWEKE--EKIRELEEKMH-EQEKIREQEEKRQEEEKIREQE 376
Query: 133 HLEEEE---YLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLE 189
+E+E + +E E+E+ I E + + + E+EE +G+ +EEK E+EE ++
Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQ----EQEEKMGE----QEEKMWEQEEEMQ 428
Query: 190 EEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRD 227
E+E EK + K +K ++E + Q ++++
Sbjct: 429 EQE--EKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 464
Score = 56.2 bits (134), Expect = 1e-07
Identities = 57/211 (27%), Positives = 108/211 (51%), Gaps = 37/211 (17%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEE--YLGKEEYLKEEEYLG 87
EKE+ EL EE + ++ + E +++E + E+E +E+E +EE ++E+E
Sbjct: 341 EKEEKIREL-EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 399
Query: 88 KEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYL---------------EEEEYLGKEE 132
+E+ +E EK G EE+ + +EEE +E + E+EE + ++E
Sbjct: 400 REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 459
Query: 133 HL--EEEEYLGK-EGYL--------EKEDYI----EEVDYLGKKAYLEEEEYLGKKSYL- 176
+ E+EE +G+ EG + E+E+ + E++ KK +EE+ ++ +
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 519
Query: 177 -EEEKALEKEENL--EEEEALEKEENLDGKE 204
+EEK E+EE + +EE+ E+EE + +E
Sbjct: 520 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 550
Score = 55.8 bits (133), Expect = 1e-07
Identities = 55/208 (26%), Positives = 108/208 (51%), Gaps = 17/208 (8%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESL-EDKEYLEEEEDL---EEEEYLGKEEYLKEEEY 85
E+E+ E +E+ + E + E + E +E + +E++ +EE+ EE + E+E
Sbjct: 299 EREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 358
Query: 86 LGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHL--EEEEYLG-- 141
+ ++E +EE EK E+ + E + + +E E+EE + ++E + E+EE +G
Sbjct: 359 IREQEEKRQEE--EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ 416
Query: 142 KEGYLEKEDYIEEVDYLGKKAYLEEEEY--LGKKSYLEEEKALEKEENLEEEEALEKEEN 199
+E E+E+ ++E + +K +EE+ KK +EEK E+EE ++E+E EK
Sbjct: 417 EEKMWEQEEEMQEQE---EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE--EKMGE 471
Query: 200 LDGKENLYKKYLKEPKASYSSQTMLLRD 227
+GK + ++E + Q +R+
Sbjct: 472 QEGKMCEQEAKMQEQEEKMRRQEEKIRE 499
Score = 54.7 bits (130), Expect = 3e-07
Identities = 53/204 (25%), Positives = 104/204 (50%), Gaps = 15/204 (7%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDL--EEEEYLGKEEYLKEEEYLG 87
++E+ E ++ Q+ + E + E +E + E+E++ E+EE +G++E E+
Sbjct: 367 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQE----EKMWE 422
Query: 88 KEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLE 147
+EE ++E+E EK EE+ +E++ +E + E+E + +E+ + E GK E
Sbjct: 423 QEEEMQEQE--EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 148 KEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEE--ALEKEENLDGKEN 205
+ +E ++ + E+E KK +EEK E+EE ++E+E E+EE + +E
Sbjct: 481 AKMQEQEEKMRRQEEKIREQE---KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 537
Query: 206 LYKKYLKEPKASYSSQTMLLRDAR 229
K +E K + M ++ R
Sbjct: 538 --KMQEQEEKMRRQEEKMREQEVR 559
Score = 51.6 bits (122), Expect = 2e-06
Identities = 56/216 (25%), Positives = 105/216 (48%), Gaps = 23/216 (10%)
Query: 21 QYSTQNLPSEKEDTEVELDEESLQDESP-FSPEGESLEDKEYLEEEED--------LEEE 71
Q + + L + E ++ L ++ LQ E+ E +S+ K + EE+ +EE
Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 288
Query: 72 EYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYL--EEEEYLG 129
+ +EE ++E +EE ++E+E EK EE+ +EE KE + +EE
Sbjct: 289 KMWRQEEKIQE-----REEKIQEQE--EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341
Query: 130 KEEHLE--EEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEEN 187
KEE + EE+ +E E+E+ +E + + ++ +E+E K + +EEK E+EE
Sbjct: 342 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE---AKMWRQEEKIREQEEK 398
Query: 188 LEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTM 223
+ E+E + +E+ E K + +E + + M
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKM 434
Score = 50.8 bits (120), Expect = 4e-06
Identities = 49/172 (28%), Positives = 90/172 (52%), Gaps = 21/172 (12%)
Query: 30 EKEDTEVELDEESLQDESPFSPEGESL--EDKEYLEEEEDLEEEEYLGKEEYLKEEEYLG 87
E+E+ E +EE + E + E + ++K+ E+EE + E+E + +E+ K E G
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG 474
Query: 88 K--EEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGY 145
K E+ + +E EK +EE I E+E +E +EE+ +EE ++E+E E
Sbjct: 475 KMCEQEAKMQEQEEK--MRRQEEKIREQEKKIRE---QEEKIREQEEMMQEQE----EKM 525
Query: 146 LEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKE 197
E+E+ + E ++ ++E+E +K +EEK E+E L ++E +E
Sbjct: 526 WEQEEKMCE-----QEEKMQEQE---EKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 33.9 bits (76), Expect = 0.52
Identities = 27/118 (22%), Positives = 62/118 (52%), Gaps = 9/118 (7%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESL---EDKEYLEEEEDLEEEEYLGKEEYLK 81
+ + E+E+ E + + + E+ + E + E+K +E++ E+EE + ++E +
Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Query: 82 EEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEY 139
+E+ EE + E+E EK EE+ +EE+ +E + E+E +++ + +E+
Sbjct: 519 QEQ----EEKMWEQE--EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 57.0 bits (136), Expect = 6e-08
Identities = 107/429 (24%), Positives = 179/429 (41%), Gaps = 53/429 (12%)
Query: 81 KEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYL 140
+EEE KE+ L++ + ++ E +E ++ L +E L +E+ + E E E +
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
Query: 141 GKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEK----ALEKEENLEEEEALEK 196
+ K+ +EE+ + +A LEEEE G++ E +K L+ EE LEEEEA +
Sbjct: 910 -RVRLAAKKQELEEILH-EMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
Query: 197 EENLD--GKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPV 254
+ L+ E KK E L ++ + + S +TT L A
Sbjct: 968 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1027
Query: 255 SESATES--SELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPE---EHV 309
++ ES SEL + L + ++ R ++ LK K E + + + +
Sbjct: 1028 LKNKHESMISELEVRLKKEEKS--------RQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
Query: 310 NTKVQQKKEENVL---------EFASKENFWDGI--TDESIDKLEVEDLD-ENFLNSSYQ 357
K+Q K+E L E A K N I + I L+ EDLD E + +
Sbjct: 1080 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ-EDLDSERAARNKAE 1138
Query: 358 TVFKTIIKEM-AAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYE---KFKETILRIKR 413
+ + +E+ A ELE+ D T+ R + V +LKK + + E ++ R
Sbjct: 1139 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1198
Query: 414 RREAQKLTEMTSFTFHL--------MSKPTPEKPETEEI-------QKPQRVVHHRKKLE 458
++ AQ + E+T +K T EK + Q Q V H +KKLE
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 459 RDKEWIQKK 467
+ +Q K
Sbjct: 1259 AQVQELQSK 1267
Score = 39.3 bits (90), Expect = 0.012
Identities = 68/328 (20%), Positives = 141/328 (42%), Gaps = 28/328 (8%)
Query: 26 NLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEY 85
+L S+ +DT+ L EE+ Q + + + E++ L+++ D E E E ++
Sbjct: 1312 SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1371
Query: 86 LGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEE----EYLGKEEHLEEEEYLG 141
+ + +++ LEE + ++E EE+ + L K ++ ++E
Sbjct: 1372 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL-- 1429
Query: 142 KEGYLEKEDYIEEVDYLGKK-----AYLEEEEYLGKKSYLEEEKALEKEENLEEEEALE- 195
+ ++ ++ + V L KK L EE+ + K Y +E E E +E +AL
Sbjct: 1430 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK-YADERDRAEAEAREKETKALSL 1488
Query: 196 ---KEENLDGKENLYK--KYLK-EPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFA 249
EE L+ KE L + K LK E + SS+ + ++ + + T + T
Sbjct: 1489 ARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1548
Query: 250 TPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEH- 308
ATE ++L L + ++ Q + + L+++ E +E +L + H
Sbjct: 1549 EELEDELQATEDAKLRLEVNMQALKGQFE--------RDLQARDEQNEEKRRQLQRQLHE 1600
Query: 309 VNTKVQQKKEENVLEFASKENFWDGITD 336
T+++ ++++ L A+K+ + D
Sbjct: 1601 YETELEDERKQRALAAAAKKKLEGDLKD 1628
Score = 37.7 bits (86), Expect = 0.036
Identities = 58/299 (19%), Positives = 123/299 (41%), Gaps = 37/299 (12%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEE 84
+ L + + E EL++E Q + + + D + LE + D G+EE +K+
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD---SAIKGREEAIKQLR 1648
Query: 85 YLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEG 144
L + + + + LE A +E + +E K LE + + +E L E K+
Sbjct: 1649 KL-QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEAD-LMQLQEDLAAAERARKQA 1706
Query: 145 YLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKE 204
LEKE+ EE+ G+ + +E++ LE EEE E++ N++
Sbjct: 1707 DLEKEELAEEL----------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
Query: 205 NLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSEL 264
+ +K ++ + + A+ ++ Q+ ++ EL
Sbjct: 1757 DRVRKATQQAEQLSNELATERSTAQKNESARQQL-------------------ERQNKEL 1797
Query: 265 LLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLE 323
L+ A ++ + ++ + +L++K +E + A E+ TK ++K++ + E
Sbjct: 1798 RSKLHEMEGAVKSKF---KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1853
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 57.0 bits (136), Expect = 6e-08
Identities = 107/429 (24%), Positives = 179/429 (41%), Gaps = 53/429 (12%)
Query: 81 KEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYL 140
+EEE KE+ L++ + ++ E +E ++ L +E L +E+ + E E E +
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916
Query: 141 GKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEK----ALEKEENLEEEEALEK 196
+ K+ +EE+ + +A LEEEE G++ E +K L+ EE LEEEEA +
Sbjct: 917 -RVRLAAKKQELEEILH-EMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974
Query: 197 EENLD--GKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPV 254
+ L+ E KK E L ++ + + S +TT L A
Sbjct: 975 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1034
Query: 255 SESATES--SELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPE---EHV 309
++ ES SEL + L + ++ R ++ LK K E + + + +
Sbjct: 1035 LKNKHESMISELEVRLKKEEKS--------RQELEKLKRKLEGDASDFHEQIADLQAQIA 1086
Query: 310 NTKVQQKKEENVL---------EFASKENFWDGI--TDESIDKLEVEDLD-ENFLNSSYQ 357
K+Q K+E L E A K N I + I L+ EDLD E + +
Sbjct: 1087 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ-EDLDSERAARNKAE 1145
Query: 358 TVFKTIIKEM-AAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYE---KFKETILRIKR 413
+ + +E+ A ELE+ D T+ R + V +LKK + + E ++ R
Sbjct: 1146 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1205
Query: 414 RREAQKLTEMTSFTFHL--------MSKPTPEKPETEEI-------QKPQRVVHHRKKLE 458
++ AQ + E+T +K T EK + Q Q V H +KKLE
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 459 RDKEWIQKK 467
+ +Q K
Sbjct: 1266 AQVQELQSK 1274
Score = 39.3 bits (90), Expect = 0.012
Identities = 68/328 (20%), Positives = 141/328 (42%), Gaps = 28/328 (8%)
Query: 26 NLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEY 85
+L S+ +DT+ L EE+ Q + + + E++ L+++ D E E E ++
Sbjct: 1319 SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1378
Query: 86 LGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEE----EYLGKEEHLEEEEYLG 141
+ + +++ LEE + ++E EE+ + L K ++ ++E
Sbjct: 1379 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL-- 1436
Query: 142 KEGYLEKEDYIEEVDYLGKK-----AYLEEEEYLGKKSYLEEEKALEKEENLEEEEALE- 195
+ ++ ++ + V L KK L EE+ + K Y +E E E +E +AL
Sbjct: 1437 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK-YADERDRAEAEAREKETKALSL 1495
Query: 196 ---KEENLDGKENLYK--KYLK-EPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFA 249
EE L+ KE L + K LK E + SS+ + ++ + + T + T
Sbjct: 1496 ARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1555
Query: 250 TPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEH- 308
ATE ++L L + ++ Q + + L+++ E +E +L + H
Sbjct: 1556 EELEDELQATEDAKLRLEVNMQALKGQFE--------RDLQARDEQNEEKRRQLQRQLHE 1607
Query: 309 VNTKVQQKKEENVLEFASKENFWDGITD 336
T+++ ++++ L A+K+ + D
Sbjct: 1608 YETELEDERKQRALAAAAKKKLEGDLKD 1635
Score = 37.7 bits (86), Expect = 0.036
Identities = 58/299 (19%), Positives = 123/299 (41%), Gaps = 37/299 (12%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEE 84
+ L + + E EL++E Q + + + D + LE + D G+EE +K+
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD---SAIKGREEAIKQLR 1655
Query: 85 YLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEG 144
L + + + + LE A +E + +E K LE + + +E L E K+
Sbjct: 1656 KL-QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEAD-LMQLQEDLAAAERARKQA 1713
Query: 145 YLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKE 204
LEKE+ EE+ G+ + +E++ LE EEE E++ N++
Sbjct: 1714 DLEKEELAEEL----------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1763
Query: 205 NLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSEL 264
+ +K ++ + + A+ ++ Q+ ++ EL
Sbjct: 1764 DRVRKATQQAEQLSNELATERSTAQKNESARQQL-------------------ERQNKEL 1804
Query: 265 LLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLE 323
L+ A ++ + ++ + +L++K +E + A E+ TK ++K++ + E
Sbjct: 1805 RSKLHEMEGAVKSKF---KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 57.0 bits (136), Expect = 6e-08
Identities = 107/429 (24%), Positives = 179/429 (41%), Gaps = 53/429 (12%)
Query: 81 KEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYL 140
+EEE KE+ L++ + ++ E +E ++ L +E L +E+ + E E E +
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916
Query: 141 GKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEK----ALEKEENLEEEEALEK 196
+ K+ +EE+ + +A LEEEE G++ E +K L+ EE LEEEEA +
Sbjct: 917 -RVRLAAKKQELEEILH-EMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974
Query: 197 EENLD--GKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPV 254
+ L+ E KK E L ++ + + S +TT L A
Sbjct: 975 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1034
Query: 255 SESATES--SELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPE---EHV 309
++ ES SEL + L + ++ R ++ LK K E + + + +
Sbjct: 1035 LKNKHESMISELEVRLKKEEKS--------RQELEKLKRKLEGDASDFHEQIADLQAQIA 1086
Query: 310 NTKVQQKKEENVL---------EFASKENFWDGI--TDESIDKLEVEDLD-ENFLNSSYQ 357
K+Q K+E L E A K N I + I L+ EDLD E + +
Sbjct: 1087 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ-EDLDSERAARNKAE 1145
Query: 358 TVFKTIIKEM-AAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYE---KFKETILRIKR 413
+ + +E+ A ELE+ D T+ R + V +LKK + + E ++ R
Sbjct: 1146 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1205
Query: 414 RREAQKLTEMTSFTFHL--------MSKPTPEKPETEEI-------QKPQRVVHHRKKLE 458
++ AQ + E+T +K T EK + Q Q V H +KKLE
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 459 RDKEWIQKK 467
+ +Q K
Sbjct: 1266 AQVQELQSK 1274
Score = 39.3 bits (90), Expect = 0.012
Identities = 68/328 (20%), Positives = 141/328 (42%), Gaps = 28/328 (8%)
Query: 26 NLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEY 85
+L S+ +DT+ L EE+ Q + + + E++ L+++ D E E E ++
Sbjct: 1319 SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1378
Query: 86 LGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEE----EYLGKEEHLEEEEYLG 141
+ + +++ LEE + ++E EE+ + L K ++ ++E
Sbjct: 1379 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL-- 1436
Query: 142 KEGYLEKEDYIEEVDYLGKK-----AYLEEEEYLGKKSYLEEEKALEKEENLEEEEALE- 195
+ ++ ++ + V L KK L EE+ + K Y +E E E +E +AL
Sbjct: 1437 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK-YADERDRAEAEAREKETKALSL 1495
Query: 196 ---KEENLDGKENLYK--KYLK-EPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFA 249
EE L+ KE L + K LK E + SS+ + ++ + + T + T
Sbjct: 1496 ARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1555
Query: 250 TPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEH- 308
ATE ++L L + ++ Q + + L+++ E +E +L + H
Sbjct: 1556 EELEDELQATEDAKLRLEVNMQALKGQFE--------RDLQARDEQNEEKRRQLQRQLHE 1607
Query: 309 VNTKVQQKKEENVLEFASKENFWDGITD 336
T+++ ++++ L A+K+ + D
Sbjct: 1608 YETELEDERKQRALAAAAKKKLEGDLKD 1635
Score = 37.7 bits (86), Expect = 0.036
Identities = 58/299 (19%), Positives = 123/299 (41%), Gaps = 37/299 (12%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEE 84
+ L + + E EL++E Q + + + D + LE + D G+EE +K+
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD---SAIKGREEAIKQLR 1655
Query: 85 YLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEG 144
L + + + + LE A +E + +E K LE + + +E L E K+
Sbjct: 1656 KL-QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEAD-LMQLQEDLAAAERARKQA 1713
Query: 145 YLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKE 204
LEKE+ EE+ G+ + +E++ LE EEE E++ N++
Sbjct: 1714 DLEKEELAEEL----------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1763
Query: 205 NLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSEL 264
+ +K ++ + + A+ ++ Q+ ++ EL
Sbjct: 1764 DRVRKATQQAEQLSNELATERSTAQKNESARQQL-------------------ERQNKEL 1804
Query: 265 LLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLE 323
L+ A ++ + ++ + +L++K +E + A E+ TK ++K++ + E
Sbjct: 1805 RSKLHEMEGAVKSKF---KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 57.0 bits (136), Expect = 6e-08
Identities = 107/429 (24%), Positives = 179/429 (41%), Gaps = 53/429 (12%)
Query: 81 KEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYL 140
+EEE KE+ L++ + ++ E +E ++ L +E L +E+ + E E E +
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
Query: 141 GKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEK----ALEKEENLEEEEALEK 196
+ K+ +EE+ + +A LEEEE G++ E +K L+ EE LEEEEA +
Sbjct: 910 -RVRLAAKKQELEEILH-EMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
Query: 197 EENLD--GKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPV 254
+ L+ E KK E L ++ + + S +TT L A
Sbjct: 968 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1027
Query: 255 SESATES--SELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPE---EHV 309
++ ES SEL + L + ++ R ++ LK K E + + + +
Sbjct: 1028 LKNKHESMISELEVRLKKEEKS--------RQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
Query: 310 NTKVQQKKEENVL---------EFASKENFWDGI--TDESIDKLEVEDLD-ENFLNSSYQ 357
K+Q K+E L E A K N I + I L+ EDLD E + +
Sbjct: 1080 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ-EDLDSERAARNKAE 1138
Query: 358 TVFKTIIKEM-AAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYE---KFKETILRIKR 413
+ + +E+ A ELE+ D T+ R + V +LKK + + E ++ R
Sbjct: 1139 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1198
Query: 414 RREAQKLTEMTSFTFHL--------MSKPTPEKPETEEI-------QKPQRVVHHRKKLE 458
++ AQ + E+T +K T EK + Q Q V H +KKLE
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 459 RDKEWIQKK 467
+ +Q K
Sbjct: 1259 AQVQELQSK 1267
Score = 39.3 bits (90), Expect = 0.012
Identities = 68/328 (20%), Positives = 141/328 (42%), Gaps = 28/328 (8%)
Query: 26 NLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEY 85
+L S+ +DT+ L EE+ Q + + + E++ L+++ D E E E ++
Sbjct: 1312 SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1371
Query: 86 LGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEE----EYLGKEEHLEEEEYLG 141
+ + +++ LEE + ++E EE+ + L K ++ ++E
Sbjct: 1372 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL-- 1429
Query: 142 KEGYLEKEDYIEEVDYLGKK-----AYLEEEEYLGKKSYLEEEKALEKEENLEEEEALE- 195
+ ++ ++ + V L KK L EE+ + K Y +E E E +E +AL
Sbjct: 1430 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK-YADERDRAEAEAREKETKALSL 1488
Query: 196 ---KEENLDGKENLYK--KYLK-EPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFA 249
EE L+ KE L + K LK E + SS+ + ++ + + T + T
Sbjct: 1489 ARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1548
Query: 250 TPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEH- 308
ATE ++L L + ++ Q + + L+++ E +E +L + H
Sbjct: 1549 EELEDELQATEDAKLRLEVNMQALKGQFE--------RDLQARDEQNEEKRRQLQRQLHE 1600
Query: 309 VNTKVQQKKEENVLEFASKENFWDGITD 336
T+++ ++++ L A+K+ + D
Sbjct: 1601 YETELEDERKQRALAAAAKKKLEGDLKD 1628
Score = 37.7 bits (86), Expect = 0.036
Identities = 58/299 (19%), Positives = 123/299 (41%), Gaps = 37/299 (12%)
Query: 25 QNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEE 84
+ L + + E EL++E Q + + + D + LE + D G+EE +K+
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD---SAIKGREEAIKQLR 1648
Query: 85 YLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEG 144
L + + + + LE A +E + +E K LE + + +E L E K+
Sbjct: 1649 KL-QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEAD-LMQLQEDLAAAERARKQA 1706
Query: 145 YLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKE 204
LEKE+ EE+ G+ + +E++ LE EEE E++ N++
Sbjct: 1707 DLEKEELAEEL----------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
Query: 205 NLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSEL 264
+ +K ++ + + A+ ++ Q+ ++ EL
Sbjct: 1757 DRVRKATQQAEQLSNELATERSTAQKNESARQQL-------------------ERQNKEL 1797
Query: 265 LLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLE 323
L+ A ++ + ++ + +L++K +E + A E+ TK ++K++ + E
Sbjct: 1798 RSKLHEMEGAVKSKF---KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1853
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 56.6 bits (135), Expect = 8e-08
Identities = 41/101 (40%), Positives = 59/101 (58%), Gaps = 10/101 (9%)
Query: 47 SPFSPEGESL-------EDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLE--EEEY 97
SP E +SL E+++ ++EE+ ++E KE +EEE +EE +E EEE
Sbjct: 262 SPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEE 321
Query: 98 LEKAGYLEE-EEYIEEEEYLGKEGYLEEEEYLGKEEHLEEE 137
+E+A Y+EE EE +EEEE +E LEE E G+E HL E
Sbjct: 322 VEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLE 362
Score = 54.3 bits (129), Expect = 4e-07
Identities = 39/107 (36%), Positives = 59/107 (55%), Gaps = 9/107 (8%)
Query: 31 KEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEE 90
+E+ E + D+E D+ + S E++E +EEE++E+EE EE ++E EY+ + E
Sbjct: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE----EEEVEEAEYVEEGE 332
Query: 91 HLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEE 137
EEE LE EEEE +EE E G+E +L E L EE+
Sbjct: 333 EELEEEELE-----EEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEK 374
Score = 54.3 bits (129), Expect = 4e-07
Identities = 35/81 (43%), Positives = 52/81 (64%), Gaps = 8/81 (9%)
Query: 29 SEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEE-EEDLEEEEYLGKEEYLKEEEYLG 87
+ +E+ EVE +EE ++DE E E +E+ EY+EE EE+LEEEE +EE L+E E G
Sbjct: 300 ASEEEEEVEDEEEEVEDE-----EEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRG 354
Query: 88 KEEHLEEEEYLEKAGYLEEEE 108
+E HL E + + ++E EE
Sbjct: 355 EEFHLPLE--MPLSIFVEAEE 373
Score = 47.4 bits (111), Expect = 5e-05
Identities = 58/196 (29%), Positives = 89/196 (45%), Gaps = 33/196 (16%)
Query: 16 PPTTPQYSTQNLPSE-KEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYL 74
PP T Q+ + + ++ +VE +E+L+ + + GE+ + + +E
Sbjct: 186 PPNTTQFIMNQIYEDMRQQEKVERQQEALRAQKA-TVSGEASPARSSGNDAPPGGSKETW 244
Query: 75 GKEEYLK---EEEYLGKEEHLEEEEYLEKAGYLEEEEYI--EEEEYL-----GKEGYLEE 124
G +E L + L + EE + L EEEE +EEEY KE EE
Sbjct: 245 GLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEE 304
Query: 125 EEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEK 184
EE +EE +E+EE E +E+ +Y+EE EEE LEEE+ E+
Sbjct: 305 EEVEDEEEEVEDEE----EEEVEEAEYVEE----------GEEE-------LEEEELEEE 343
Query: 185 EENLEEEEALEKEENL 200
EE LEE E +E +L
Sbjct: 344 EEVLEENEQRGEEFHL 359
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.130 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,267,614
Number of Sequences: 37866
Number of extensions: 1675236
Number of successful extensions: 28656
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 283
Number of HSP's successfully gapped in prelim test: 919
Number of HSP's that attempted gapping in prelim test: 9891
Number of HSP's gapped (non-prelim): 7156
length of query: 696
length of database: 18,247,518
effective HSP length: 109
effective length of query: 587
effective length of database: 14,120,124
effective search space: 8288512788
effective search space used: 8288512788
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.