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Search of human proteins with 20986497
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
(816 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 1659 0.0
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 1659 0.0
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 1659 0.0
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 1389 0.0
gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo s... 342 8e-94
gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens] 338 2e-92
gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens] 338 2e-92
gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo s... 320 3e-87
gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens] 316 5e-86
gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo ... 308 1e-83
gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo s... 305 1e-82
gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo ... 292 1e-78
gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens] 281 1e-75
gi|149408126 nemo like kinase [Homo sapiens] 281 2e-75
gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo ... 260 4e-69
gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens] 258 1e-68
gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens] 256 5e-68
gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta... 256 8e-68
gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta... 255 1e-67
gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alph... 249 6e-66
gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha... 249 6e-66
gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alph... 247 3e-65
gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alph... 247 4e-65
gi|20986516 mitogen-activated protein kinase 14 isoform 4 [Homo ... 246 5e-65
gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta... 244 3e-64
gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta... 244 3e-64
gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo s... 243 5e-64
gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo ... 243 5e-64
gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo ... 243 5e-64
gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens] 228 1e-59
>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 1659 bits (4296), Expect = 0.0
Identities = 816/816 (100%), Positives = 816/816 (100%)
Query: 1 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET 60
MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
Sbjct: 1 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET 60
Query: 61 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI 120
IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
Sbjct: 61 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI 120
Query: 121 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH 180
LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
Sbjct: 121 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH 180
Query: 181 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT 240
RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
Sbjct: 181 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT 240
Query: 241 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS 300
QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
Sbjct: 241 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS 300
Query: 301 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA 360
LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
Sbjct: 301 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA 360
Query: 361 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP 420
PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
Sbjct: 361 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP 420
Query: 421 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK 480
SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
Sbjct: 421 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK 480
Query: 481 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER 540
AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
Sbjct: 481 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER 540
Query: 541 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV 600
KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
Sbjct: 541 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV 600
Query: 601 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS 660
QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
Sbjct: 601 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS 660
Query: 661 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS 720
TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
Sbjct: 661 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS 720
Query: 721 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD 780
QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
Sbjct: 721 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD 780
Query: 781 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP 816
WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
Sbjct: 781 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP 816
>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 1659 bits (4296), Expect = 0.0
Identities = 816/816 (100%), Positives = 816/816 (100%)
Query: 1 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET 60
MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
Sbjct: 1 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET 60
Query: 61 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI 120
IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
Sbjct: 61 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI 120
Query: 121 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH 180
LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
Sbjct: 121 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH 180
Query: 181 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT 240
RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
Sbjct: 181 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT 240
Query: 241 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS 300
QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
Sbjct: 241 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS 300
Query: 301 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA 360
LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
Sbjct: 301 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA 360
Query: 361 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP 420
PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
Sbjct: 361 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP 420
Query: 421 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK 480
SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
Sbjct: 421 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK 480
Query: 481 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER 540
AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
Sbjct: 481 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER 540
Query: 541 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV 600
KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
Sbjct: 541 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV 600
Query: 601 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS 660
QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
Sbjct: 601 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS 660
Query: 661 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS 720
TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
Sbjct: 661 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS 720
Query: 721 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD 780
QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
Sbjct: 721 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD 780
Query: 781 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP 816
WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
Sbjct: 781 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP 816
>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 1659 bits (4296), Expect = 0.0
Identities = 816/816 (100%), Positives = 816/816 (100%)
Query: 1 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET 60
MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
Sbjct: 1 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET 60
Query: 61 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI 120
IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
Sbjct: 61 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI 120
Query: 121 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH 180
LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
Sbjct: 121 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH 180
Query: 181 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT 240
RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
Sbjct: 181 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT 240
Query: 241 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS 300
QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
Sbjct: 241 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS 300
Query: 301 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA 360
LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
Sbjct: 301 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA 360
Query: 361 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP 420
PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
Sbjct: 361 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP 420
Query: 421 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK 480
SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
Sbjct: 421 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK 480
Query: 481 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER 540
AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
Sbjct: 481 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER 540
Query: 541 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV 600
KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
Sbjct: 541 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV 600
Query: 601 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS 660
QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
Sbjct: 601 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS 660
Query: 661 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS 720
TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
Sbjct: 661 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS 720
Query: 721 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD 780
QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
Sbjct: 721 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD 780
Query: 781 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP 816
WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
Sbjct: 781 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP 816
>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
Length = 677
Score = 1389 bits (3596), Expect = 0.0
Identities = 677/677 (100%), Positives = 677/677 (100%)
Query: 140 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 199
MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG
Sbjct: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
Query: 200 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 259
DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR
Sbjct: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
Query: 260 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 319
QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ
Sbjct: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
Query: 320 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 379
ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE
Sbjct: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
Query: 380 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 439
AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP
Sbjct: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300
Query: 440 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 499
PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL
Sbjct: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360
Query: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 559
EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL
Sbjct: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420
Query: 560 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 619
VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ
Sbjct: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480
Query: 620 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 679
SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS
Sbjct: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540
Query: 680 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 739
TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA
Sbjct: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600
Query: 740 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 799
GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI
Sbjct: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660
Query: 800 QMDSPMLLADLPDLQDP 816
QMDSPMLLADLPDLQDP
Sbjct: 661 QMDSPMLLADLPDLQDP 677
>gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo
sapiens]
Length = 379
Score = 342 bits (877), Expect = 8e-94
Identities = 174/340 (51%), Positives = 238/340 (70%), Gaps = 4/340 (1%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
FDVG Y ++ IG GAYG+VSSA + +VAIKKI + F+ T +RTLRE++IL
Sbjct: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQILLR 94
Query: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
F+H+N+I I+DILR + + VY+V DLME+DL++++ S Q L+ +H+ YFLYQ+LR
Sbjct: 95 FRHENVIGIRDILRAST-LEAMRDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILR 152
Query: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
GLKY+HSA V+HRDLKPSNLL+N C+LKI DFG+AR + +H F+TEYVATRWYR
Sbjct: 153 GLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYR 211
Query: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
APE+ML+ YT++ID+WSVGCI EML+ R +FPGK+Y+ QL I+ +LG+PS +
Sbjct: 212 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNC 271
Query: 289 VGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLA 348
+ + R Y+QSLP + V W ++P +D +AL LL RML F P+ RI+ AL HP+L
Sbjct: 272 IINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLE 331
Query: 349 KYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDF 388
+Y+DP DEP PF FA + + L +ER+KE I E F
Sbjct: 332 QYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETARF 371
>gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]
Length = 360
Score = 338 bits (866), Expect = 2e-92
Identities = 174/341 (51%), Positives = 235/341 (68%), Gaps = 6/341 (1%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
FDVG Y + IG GAYG+V SA + +VAIKKI + F+ T +RTLRE+KIL
Sbjct: 19 FDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKI-SPFEHQTYCQRTLREIKILLR 77
Query: 109 FKHDNIIAIKDILR-PTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLL 167
F+H+NII I DI+R PT+ + K VY+V DLME+DL++++ +Q L+ +H+ YFLYQ+L
Sbjct: 78 FRHENIIGINDIIRAPTIE--QMKDVYIVQDLMETDLYKLL-KTQHLSNDHICYFLYQIL 134
Query: 168 RGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWY 227
RGLKY+HSA V+HRDLKPSNLL+N C+LKI DFG+AR + +H F+TEYVATRWY
Sbjct: 135 RGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-VADPDHDHTGFLTEYVATRWY 193
Query: 228 RAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQ 287
RAPE+ML+ YT++ID+WSVGCI EML+ R +FPGK+Y+ QL I+ +LG+PS +
Sbjct: 194 RAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLN 253
Query: 288 AVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFL 347
+ + R Y+ SLP + VPW ++P AD +AL LL +ML F P RI AL HP+L
Sbjct: 254 CIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYL 313
Query: 348 AKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDF 388
+Y+DP DEP PF F + + L +E++KE I E F
Sbjct: 314 EQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARF 354
>gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens]
Length = 360
Score = 338 bits (866), Expect = 2e-92
Identities = 174/341 (51%), Positives = 235/341 (68%), Gaps = 6/341 (1%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
FDVG Y + IG GAYG+V SA + +VAIKKI + F+ T +RTLRE+KIL
Sbjct: 19 FDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKI-SPFEHQTYCQRTLREIKILLR 77
Query: 109 FKHDNIIAIKDILR-PTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLL 167
F+H+NII I DI+R PT+ + K VY+V DLME+DL++++ +Q L+ +H+ YFLYQ+L
Sbjct: 78 FRHENIIGINDIIRAPTIE--QMKDVYIVQDLMETDLYKLL-KTQHLSNDHICYFLYQIL 134
Query: 168 RGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWY 227
RGLKY+HSA V+HRDLKPSNLL+N C+LKI DFG+AR + +H F+TEYVATRWY
Sbjct: 135 RGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-VADPDHDHTGFLTEYVATRWY 193
Query: 228 RAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQ 287
RAPE+ML+ YT++ID+WSVGCI EML+ R +FPGK+Y+ QL I+ +LG+PS +
Sbjct: 194 RAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLN 253
Query: 288 AVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFL 347
+ + R Y+ SLP + VPW ++P AD +AL LL +ML F P RI AL HP+L
Sbjct: 254 CIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYL 313
Query: 348 AKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDF 388
+Y+DP DEP PF F + + L +E++KE I E F
Sbjct: 314 EQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARF 354
>gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo
sapiens]
Length = 357
Score = 320 bits (820), Expect = 3e-87
Identities = 162/313 (51%), Positives = 223/313 (71%), Gaps = 4/313 (1%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
FDVG Y ++ IG GAYG+VSSA + +VAIKKI + F+ T +RTLRE++IL
Sbjct: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQILLR 94
Query: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
F+H+N+I I+DILR + + VY+V DLME+DL++++ S Q L+ +H+ YFLYQ+LR
Sbjct: 95 FRHENVIGIRDILRAST-LEAMRDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILR 152
Query: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
GLKY+HSA V+HRDLKPSNLL+N C+LKI DFG+AR + +H F+TEYVATRWYR
Sbjct: 153 GLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYR 211
Query: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
APE+ML+ YT++ID+WSVGCI EML+ R +FPGK+Y+ QL I+ +LG+PS +
Sbjct: 212 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNC 271
Query: 289 VGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLA 348
+ + R Y+QSLP + V W ++P +D +AL LL RML F P+ RI+ AL HP+L
Sbjct: 272 IINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLE 331
Query: 349 KYHDPDDEPDCAP 361
+Y+DP DE +P
Sbjct: 332 QYYDPTDEVGQSP 344
>gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens]
Length = 364
Score = 316 bits (810), Expect = 5e-86
Identities = 161/340 (47%), Positives = 226/340 (66%), Gaps = 9/340 (2%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
++V + + +G+GAYG V SA Q+VA+KK+ F + +A+RT REL++LKH
Sbjct: 18 WEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKH 77
Query: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
KH+N+I + D+ P +F VY+V LM +DL+ I+ Q L+ EHV++ +YQLLR
Sbjct: 78 LKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIV-KCQALSDEHVQFLVYQLLR 136
Query: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
GLKY+HSA +IHRDLKPSN+ VNE+CEL+I DFG+AR A+ + MT YVATRWYR
Sbjct: 137 GLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLAR-----QADEE--MTGYVATRWYR 189
Query: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
APE+ML+ Y Q +D+WSVGCI E+L + LFPG +Y+ QL+ IM V+GTPSP V+
Sbjct: 190 APEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAK 249
Query: 289 VGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLA 348
+ +E R YIQSLPP +++ GA+ A+ LLGRML + R+SAA AL H + +
Sbjct: 250 ISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFS 309
Query: 349 KYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDF 388
+YHDP+DEP+ A P+D + + + T E KE E+ F
Sbjct: 310 QYHDPEDEPE-AEPYDESVEAKERTLEEWKELTYQEVLSF 348
>gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo
sapiens]
Length = 360
Score = 308 bits (789), Expect = 1e-83
Identities = 158/340 (46%), Positives = 222/340 (65%), Gaps = 9/340 (2%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
++V + Y+ + +G+GAYG V +A TG +VA+KK+ F + +AKRT REL++LKH
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
KH+N+I + D+ P EF VY+V LM +DL+ I+ Q LT +HV++ +YQ+LR
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIV-KCQKLTDDHVQFLIYQILR 136
Query: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
GLKY+HSA +IHRDLKPSNL VNE+CELKI DFG+AR MT YVATRWYR
Sbjct: 137 GLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-------MTGYVATRWYR 189
Query: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
APE+ML+ Y Q +D+WSVGCI E+L R LFPG +++ QL+LI+ ++GTP +++
Sbjct: 190 APEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK 249
Query: 289 VGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLA 348
+ +E R YIQSL + + V+ GA+ A+ LL +ML + RI+AA AL H + A
Sbjct: 250 ISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFA 309
Query: 349 KYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDF 388
+YHDPDDEP A P+D +F+ L + K E+ F
Sbjct: 310 QYHDPDDEP-VADPYDQSFESRDLLIDEWKSLTYDEVISF 348
>gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo
sapiens]
Length = 360
Score = 305 bits (781), Expect = 1e-82
Identities = 159/340 (46%), Positives = 219/340 (64%), Gaps = 9/340 (2%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
++V + Y+ + +G+GAYG V +A TG +VA+KK+ F + +AKRT REL++LKH
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
KH+N+I + D+ P EF VY+V LM +DL+ I+ Q LT +HV++ +YQ+LR
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIV-KCQKLTDDHVQFLIYQILR 136
Query: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
GLKY+HSA +IHRDLKPSNL VNE+CELKI DFG+AR MT YVATRWYR
Sbjct: 137 GLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-------MTGYVATRWYR 189
Query: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
APE+ML+ Y Q +D+WSVGCI E+L R LFPG ++++QLQ IM + GTP +I
Sbjct: 190 APEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINR 249
Query: 289 VGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLA 348
+ + R YIQSL + + V+ GA+ A+ LL +ML + RI+AA AL H + A
Sbjct: 250 MPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFA 309
Query: 349 KYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDF 388
+YHDPDDEP A P+D +F+ L + K E+ F
Sbjct: 310 QYHDPDDEP-VADPYDQSFESRDLLIDEWKSLTYDEVISF 348
>gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo
sapiens]
Length = 335
Score = 292 bits (747), Expect = 1e-78
Identities = 160/340 (47%), Positives = 213/340 (62%), Gaps = 48/340 (14%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
FDVG Y ++ IG GAYG+VSSA + +VAIKKI + F+ T +RTLRE++IL
Sbjct: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQILLR 94
Query: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
F+H+N+I I+DILR + + VY+V DLME+DL++++ S Q L+ +H+ YFLYQ+LR
Sbjct: 95 FRHENVIGIRDILRAST-LEAMRDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILR 152
Query: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
GLKY+HSA V+HRDLKPSNLL+N C+LKI DFG+AR + +H F+TEYVATRWYR
Sbjct: 153 GLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYR 211
Query: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
APE+ML+ YT++ID+WSVGCI EML+ R +FPGK+Y+ QL I+
Sbjct: 212 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHIL------------- 258
Query: 289 VGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLA 348
AL LL RML F P+ RI+ AL HP+L
Sbjct: 259 -------------------------------ALDLLDRMLTFNPNKRITVEEALAHPYLE 287
Query: 349 KYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDF 388
+Y+DP DEP PF FA + + L +ER+KE I E F
Sbjct: 288 QYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETARF 327
>gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]
Length = 365
Score = 281 bits (720), Expect = 1e-75
Identities = 149/339 (43%), Positives = 211/339 (62%), Gaps = 11/339 (3%)
Query: 61 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI 120
+G+GAYG V SA + +G++VAIKK+ F AKR REL +LKH +H+N+I + D+
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 121 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH 180
P F Y+V+ M++DL +I+ + E ++Y +YQ+L+GLKY+HSA V+H
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKIM--GMEFSEEKIQYLVYQMLKGLKYIHSAGVVH 148
Query: 181 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT 240
RDLKP NL VNE+CELKI DFG+AR + AE MT YV TRWYRAPE++LS Y
Sbjct: 149 RDLKPGNLAVNEDCELKILDFGLARH---ADAE----MTGYVVTRWYRAPEVILSWMHYN 201
Query: 241 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS 300
Q +D+WSVGCI EML + LF GK+Y+ QL I+ V G P +Q + + ++YIQS
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 301 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA 360
LP + ++P A QA LL +ML + R++AA AL HPF + DP++E +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 361 PPFDFAFDREALTRERIKEAIVAEIEDFH--ARREGIRQ 397
PFD + + E LT + K+ I EI +F AR++ R+
Sbjct: 322 QPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRR 360
>gi|149408126 nemo like kinase [Homo sapiens]
Length = 527
Score = 281 bits (719), Expect = 2e-75
Identities = 170/391 (43%), Positives = 234/391 (59%), Gaps = 35/391 (8%)
Query: 16 EPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEII--ETIGNGAYGVVSSAR 73
+ PGP A PA A+ AA +KA + + +I IG GA+GVV S
Sbjct: 101 QAPGPAAAAPAQVQAAAAAT----VKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSVT 156
Query: 74 RRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPT-VPYGEFKS 132
G++VA+KK+PN F + + KR RELK+L FKHDN+++ DIL+P + Y F+
Sbjct: 157 DPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHIDY--FEE 214
Query: 133 VYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNE 192
+YVV +LM+SDLH+II S QPL+ +HV+ FLYQ+LRGLKY+HSA ++HRD+KP NLLVN
Sbjct: 215 IYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNS 274
Query: 193 NCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIF 252
NC LKI DFG+AR + MT+ V T++YRAPE+++ Y+ AID+WSVGCIF
Sbjct: 275 NCVLKICDFGLAR---VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIF 331
Query: 253 GEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQP-VP-WE 310
E+L RR LF ++ + QL LI +LGTPS ++ E +A+I P +QP +P
Sbjct: 332 AELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMR-TACEGAKAHILRGPHKQPSLPVLY 390
Query: 311 TVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFL----AKYH--------------- 351
T+ A +A+ LL RML F+PS RISA AL HP+L +YH
Sbjct: 391 TLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTGRV 450
Query: 352 -DPDDEPDCAPPFDFAFDREALTRERIKEAI 381
D EP P FD F++ + ++KE I
Sbjct: 451 YTSDFEPVTNPKFDDTFEKNLSSVRQVKEII 481
>gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo
sapiens]
Length = 297
Score = 260 bits (664), Expect = 4e-69
Identities = 129/269 (47%), Positives = 182/269 (67%), Gaps = 8/269 (2%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
++V + Y+ + +G+GAYG V +A TG +VA+KK+ F + +AKRT REL++LKH
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
KH+N+I + D+ P EF VY+V LM +DL+ I+ Q LT +HV++ +YQ+LR
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIV-KCQKLTDDHVQFLIYQILR 136
Query: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
GLKY+HSA +IHRDLKPSNL VNE+CELKI DFG+AR MT YVATRWYR
Sbjct: 137 GLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-------MTGYVATRWYR 189
Query: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
APE+ML+ Y Q +D+WSVGCI E+L R LFPG +++ QL+LI+ ++GTP +++
Sbjct: 190 APEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK 249
Query: 289 VGAERVRAYIQSLPPRQPVPWETVYPGAD 317
+ +E R YIQSL + + V+ GA+
Sbjct: 250 ISSESARNYIQSLTQMPKMNFANVFIGAN 278
>gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens]
Length = 367
Score = 258 bits (660), Expect = 1e-68
Identities = 134/345 (38%), Positives = 206/345 (59%), Gaps = 9/345 (2%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
++V Y ++ +G+GAYG V SA TG +VAIKK+ F AKR REL++LKH
Sbjct: 21 WEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKH 80
Query: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
+H+N+I + D+ P +F Y+V+ M +DL +++ + L + +++ +YQ+L+
Sbjct: 81 MRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM-KHEKLGEDRIQFLVYQMLK 139
Query: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
GL+Y+H+A +IHRDLKP NL VNE+CELKI DFG+AR + MT YV TRWYR
Sbjct: 140 GLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSE-------MTGYVVTRWYR 192
Query: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
APE++L+ YTQ +D+WSVGCI EM+ + LF G +++ QL+ IM V GTP +Q
Sbjct: 193 APEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQR 252
Query: 289 VGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLA 348
+ ++ + Y++ LP + + ++ A A++LL +ML + R++A AL HP+
Sbjct: 253 LQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFE 312
Query: 349 KYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARRE 393
HD +DEP +D +FD T + K E+ F R+
Sbjct: 313 SLHDTEDEPQ-VQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQ 356
>gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]
Length = 544
Score = 256 bits (655), Expect = 5e-68
Identities = 165/440 (37%), Positives = 236/440 (53%), Gaps = 38/440 (8%)
Query: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHF-KHDN 113
Y + +G GAYG+V A R TG+ VAIKKI +AF T+A+RT RE+ +L+ F H N
Sbjct: 13 YLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGDHPN 72
Query: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYM 173
II++ D++R + +Y+V + M++DL+ +I L HVR YQLLR +++
Sbjct: 73 IISLLDVIRAE----NDRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFL 128
Query: 174 HSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSP-AEHQYFMTEYVATRWYRAPEL 232
HS V+HRD KPSN+L++ NC +K+ DFG+AR L P +TEYVATRWYRAPE+
Sbjct: 129 HSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEV 188
Query: 233 MLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAE 292
+LS H YT +D+WS+GCI GEML R LFPG + +HQL+LI+ + PS + A+G+
Sbjct: 189 LLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSG 248
Query: 293 RVRAYIQSL--PPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKY 350
+ + L PRQ + + P +AL LL R+L F P R+SA AL+HP++ ++
Sbjct: 249 CRASVLHQLGSRPRQTLD-ALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRF 307
Query: 351 HDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVAS 410
H P DE + REA R R E + + ++ +R + Q I +
Sbjct: 308 HCPSDE----------WAREADVRPRAHEGVQLSVPEYRSR---VYQMILECGGSSGTSR 354
Query: 411 EPGCPDVEMPSP---WAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPP---PVSEPAP 464
E G P+ PS P D + S P P P P Q P P +P
Sbjct: 355 EKG-PEGVSPSQAHLHKPRADPQLPSRTPVQGPRPRP---------QSSPGHDPAEHESP 404
Query: 465 PKKDGAISDNTKAALKAALL 484
N+ L+ ALL
Sbjct: 405 RAAKNVPRQNSAPLLQTALL 424
>gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta1
[Homo sapiens]
Length = 382
Score = 256 bits (653), Expect = 8e-68
Identities = 148/376 (39%), Positives = 222/376 (59%), Gaps = 28/376 (7%)
Query: 46 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105
D TF V Y+ ++ IG+GA G+V +A + G VA+KK+ F T+AKR REL +
Sbjct: 17 DSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVL 76
Query: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165
LK H NII++ ++ P EF+ VY+V++LM+++L Q+IH L E + Y LYQ
Sbjct: 77 LKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH--MELDHERMSYLLYQ 134
Query: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225
+L G+K++HSA +IHRDLKPSN++V +C LKI DFG+AR CT+ + MT YV TR
Sbjct: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTN-----FMMTPYVVTR 189
Query: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAV 285
+YRAPE++L + Y + +D+WSVGCI EM+ + LFPG++Y+ Q ++ LGTPS
Sbjct: 190 YYRAPEVILGM-GYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEF 248
Query: 286 IQAVGAERVRAYIQSLPPRQPVPWETVYPG------------ADRQALSLLGRMLRFEPS 333
++ + VR Y+++ P + +E ++P QA LL +ML +P
Sbjct: 249 MKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPD 307
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPP--FDFAFDREALTRERIKEAIVAEIEDFHAR 391
RIS ALRHP++ ++DP E + PP +D + E KE I E+ D+ R
Sbjct: 308 KRISVDEALRHPYITVWYDP-AEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEER 366
Query: 392 -REGIRQQIRFQPSLQ 406
+ G+ ++ QPS Q
Sbjct: 367 SKNGV---VKDQPSAQ 379
>gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta2
[Homo sapiens]
Length = 424
Score = 255 bits (652), Expect = 1e-67
Identities = 149/380 (39%), Positives = 224/380 (58%), Gaps = 28/380 (7%)
Query: 46 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105
D TF V Y+ ++ IG+GA G+V +A + G VA+KK+ F T+AKR REL +
Sbjct: 17 DSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVL 76
Query: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165
LK H NII++ ++ P EF+ VY+V++LM+++L Q+IH L E + Y LYQ
Sbjct: 77 LKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH--MELDHERMSYLLYQ 134
Query: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225
+L G+K++HSA +IHRDLKPSN++V +C LKI DFG+AR CT+ + MT YV TR
Sbjct: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTN-----FMMTPYVVTR 189
Query: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAV 285
+YRAPE++L + Y + +D+WSVGCI EM+ + LFPG++Y+ Q ++ LGTPS
Sbjct: 190 YYRAPEVILGM-GYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEF 248
Query: 286 IQAVGAERVRAYIQSLPPRQPVPWETVYPG------------ADRQALSLLGRMLRFEPS 333
++ + VR Y+++ P + +E ++P QA LL +ML +P
Sbjct: 249 MKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPD 307
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPP--FDFAFDREALTRERIKEAIVAEIEDFHAR 391
RIS ALRHP++ ++DP E + PP +D + E KE I E+ D+ R
Sbjct: 308 KRISVDEALRHPYITVWYDP-AEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEER 366
Query: 392 -REGIRQQIRFQPSLQPVAS 410
+ G+ ++ QPS V+S
Sbjct: 367 SKNGV---VKDQPSDAAVSS 383
>gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alpha2
[Homo sapiens]
Length = 427
Score = 249 bits (637), Expect = 6e-66
Identities = 152/374 (40%), Positives = 219/374 (58%), Gaps = 28/374 (7%)
Query: 46 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105
D TF V Y+ ++ IG+GA G+V +A + + VAIKK+ F T+AKR REL +
Sbjct: 17 DSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVL 76
Query: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165
+K H NII + ++ P EF+ VY+V++LM+++L Q+I L E + Y LYQ
Sbjct: 77 MKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI--QMELDHERMSYLLYQ 134
Query: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225
+L G+K++HSA +IHRDLKPSN++V +C LKI DFG+AR TS + MT YV TR
Sbjct: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTS-----FMMTPYVVTR 189
Query: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAV 285
+YRAPE++L + Y + +DLWSVGCI GEM+ + LFPG++Y+ Q ++ LGTP P
Sbjct: 190 YYRAPEVILGM-GYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEF 248
Query: 286 IQAVGAERVRAYIQSLPPRQPVPWETVYPG----AD--------RQALSLLGRMLRFEPS 333
++ + VR Y+++ P +E ++P AD QA LL +ML + S
Sbjct: 249 MKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDAS 307
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPPF--DFAFDREALTRERIKEAIVAEIEDFHAR 391
RIS AL+HP++ ++DP E + PP D D T E KE I E+ D R
Sbjct: 308 KRISVDEALQHPYINVWYDP-SEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEER 366
Query: 392 -REGIRQQIRFQPS 404
+ G+ IR QPS
Sbjct: 367 TKNGV---IRGQPS 377
>gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha1
[Homo sapiens]
Length = 384
Score = 249 bits (637), Expect = 6e-66
Identities = 152/374 (40%), Positives = 219/374 (58%), Gaps = 28/374 (7%)
Query: 46 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105
D TF V Y+ ++ IG+GA G+V +A + + VAIKK+ F T+AKR REL +
Sbjct: 17 DSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVL 76
Query: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165
+K H NII + ++ P EF+ VY+V++LM+++L Q+I L E + Y LYQ
Sbjct: 77 MKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI--QMELDHERMSYLLYQ 134
Query: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225
+L G+K++HSA +IHRDLKPSN++V +C LKI DFG+AR TS + MT YV TR
Sbjct: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTS-----FMMTPYVVTR 189
Query: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAV 285
+YRAPE++L + Y + +DLWSVGCI GEM+ + LFPG++Y+ Q ++ LGTP P
Sbjct: 190 YYRAPEVILGM-GYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEF 248
Query: 286 IQAVGAERVRAYIQSLPPRQPVPWETVYPG----AD--------RQALSLLGRMLRFEPS 333
++ + VR Y+++ P +E ++P AD QA LL +ML + S
Sbjct: 249 MKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDAS 307
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPPF--DFAFDREALTRERIKEAIVAEIEDFHAR 391
RIS AL+HP++ ++DP E + PP D D T E KE I E+ D R
Sbjct: 308 KRISVDEALQHPYINVWYDP-SEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEER 366
Query: 392 -REGIRQQIRFQPS 404
+ G+ IR QPS
Sbjct: 367 TKNGV---IRGQPS 377
>gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alpha1
[Homo sapiens]
Length = 382
Score = 247 bits (631), Expect = 3e-65
Identities = 145/376 (38%), Positives = 220/376 (58%), Gaps = 28/376 (7%)
Query: 46 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105
D TF V Y+ ++ IG+GA G+V +A + G VA+KK+ F T+AKR REL +
Sbjct: 17 DSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVL 76
Query: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165
LK H NII++ ++ P EF+ VY+V++LM+++L Q+IH L E + Y LYQ
Sbjct: 77 LKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH--MELDHERMSYLLYQ 134
Query: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225
+L G+K++HSA +IHRDLKPSN++V +C LKI DFG+AR CT+ + MT YV TR
Sbjct: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTN-----FMMTPYVVTR 189
Query: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAV 285
+YRAPE++L + Y + +D+WSVGCI GE++ +F G +++ Q ++ LGTPS
Sbjct: 190 YYRAPEVILGM-GYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEF 248
Query: 286 IQAVGAERVRAYIQSLPPRQPVPWETVYPG------------ADRQALSLLGRMLRFEPS 333
++ + VR Y+++ P + +E ++P QA LL +ML +P
Sbjct: 249 MKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPD 307
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPP--FDFAFDREALTRERIKEAIVAEIEDFHAR 391
RIS ALRHP++ ++DP E + PP +D + E KE I E+ D+ R
Sbjct: 308 KRISVDEALRHPYITVWYDP-AEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEER 366
Query: 392 -REGIRQQIRFQPSLQ 406
+ G+ ++ QPS Q
Sbjct: 367 SKNGV---VKDQPSAQ 379
>gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alpha2
[Homo sapiens]
Length = 424
Score = 247 bits (630), Expect = 4e-65
Identities = 146/380 (38%), Positives = 222/380 (58%), Gaps = 28/380 (7%)
Query: 46 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105
D TF V Y+ ++ IG+GA G+V +A + G VA+KK+ F T+AKR REL +
Sbjct: 17 DSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVL 76
Query: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165
LK H NII++ ++ P EF+ VY+V++LM+++L Q+IH L E + Y LYQ
Sbjct: 77 LKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH--MELDHERMSYLLYQ 134
Query: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225
+L G+K++HSA +IHRDLKPSN++V +C LKI DFG+AR CT+ + MT YV TR
Sbjct: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTN-----FMMTPYVVTR 189
Query: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAV 285
+YRAPE++L + Y + +D+WSVGCI GE++ +F G +++ Q ++ LGTPS
Sbjct: 190 YYRAPEVILGM-GYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEF 248
Query: 286 IQAVGAERVRAYIQSLPPRQPVPWETVYPG------------ADRQALSLLGRMLRFEPS 333
++ + VR Y+++ P + +E ++P QA LL +ML +P
Sbjct: 249 MKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPD 307
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPP--FDFAFDREALTRERIKEAIVAEIEDFHAR 391
RIS ALRHP++ ++DP E + PP +D + E KE I E+ D+ R
Sbjct: 308 KRISVDEALRHPYITVWYDP-AEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEER 366
Query: 392 -REGIRQQIRFQPSLQPVAS 410
+ G+ ++ QPS V+S
Sbjct: 367 SKNGV---VKDQPSDAAVSS 383
>gi|20986516 mitogen-activated protein kinase 14 isoform 4 [Homo
sapiens]
Length = 307
Score = 246 bits (629), Expect = 5e-65
Identities = 120/244 (49%), Positives = 169/244 (69%), Gaps = 8/244 (3%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
++V + Y+ + +G+GAYG V +A TG +VA+KK+ F + +AKRT REL++LKH
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
KH+N+I + D+ P EF VY+V LM +DL+ I+ Q LT +HV++ +YQ+LR
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIV-KCQKLTDDHVQFLIYQILR 136
Query: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
GLKY+HSA +IHRDLKPSNL VNE+CELKI DFG+AR MT YVATRWYR
Sbjct: 137 GLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-------MTGYVATRWYR 189
Query: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
APE+ML+ Y Q +D+WSVGCI E+L R LFPG +++ QL+LI+ ++GTP +++
Sbjct: 190 APEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK 249
Query: 289 VGAE 292
+ +E
Sbjct: 250 ISSE 253
>gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta2
[Homo sapiens]
Length = 427
Score = 244 bits (622), Expect = 3e-64
Identities = 150/374 (40%), Positives = 217/374 (58%), Gaps = 28/374 (7%)
Query: 46 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105
D TF V Y+ ++ IG+GA G+V +A + + VAIKK+ F T+AKR REL +
Sbjct: 17 DSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVL 76
Query: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165
+K H NII + ++ P EF+ VY+V++LM+++L Q+I L E + Y LYQ
Sbjct: 77 MKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI--QMELDHERMSYLLYQ 134
Query: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225
+L G+K++HSA +IHRDLKPSN++V +C LKI DFG+AR TS + MT YV TR
Sbjct: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTS-----FMMTPYVVTR 189
Query: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAV 285
+YRAPE++L + Y + +D+WSVGCI GEM+ LFPG +++ Q ++ LGTP P
Sbjct: 190 YYRAPEVILGM-GYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEF 248
Query: 286 IQAVGAERVRAYIQSLPPRQPVPWETVYPG----AD--------RQALSLLGRMLRFEPS 333
++ + VR Y+++ P +E ++P AD QA LL +ML + S
Sbjct: 249 MKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDAS 307
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPPF--DFAFDREALTRERIKEAIVAEIEDFHAR 391
RIS AL+HP++ ++DP E + PP D D T E KE I E+ D R
Sbjct: 308 KRISVDEALQHPYINVWYDP-SEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEER 366
Query: 392 -REGIRQQIRFQPS 404
+ G+ IR QPS
Sbjct: 367 TKNGV---IRGQPS 377
>gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta1
[Homo sapiens]
Length = 384
Score = 244 bits (622), Expect = 3e-64
Identities = 150/374 (40%), Positives = 217/374 (58%), Gaps = 28/374 (7%)
Query: 46 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105
D TF V Y+ ++ IG+GA G+V +A + + VAIKK+ F T+AKR REL +
Sbjct: 17 DSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVL 76
Query: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165
+K H NII + ++ P EF+ VY+V++LM+++L Q+I L E + Y LYQ
Sbjct: 77 MKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI--QMELDHERMSYLLYQ 134
Query: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225
+L G+K++HSA +IHRDLKPSN++V +C LKI DFG+AR TS + MT YV TR
Sbjct: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTS-----FMMTPYVVTR 189
Query: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAV 285
+YRAPE++L + Y + +D+WSVGCI GEM+ LFPG +++ Q ++ LGTP P
Sbjct: 190 YYRAPEVILGM-GYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEF 248
Query: 286 IQAVGAERVRAYIQSLPPRQPVPWETVYPG----AD--------RQALSLLGRMLRFEPS 333
++ + VR Y+++ P +E ++P AD QA LL +ML + S
Sbjct: 249 MKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDAS 307
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPPF--DFAFDREALTRERIKEAIVAEIEDFHAR 391
RIS AL+HP++ ++DP E + PP D D T E KE I E+ D R
Sbjct: 308 KRISVDEALQHPYINVWYDP-SEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEER 366
Query: 392 -REGIRQQIRFQPS 404
+ G+ IR QPS
Sbjct: 367 TKNGV---IRGQPS 377
>gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo
sapiens]
Length = 422
Score = 243 bits (620), Expect = 5e-64
Identities = 144/374 (38%), Positives = 221/374 (59%), Gaps = 28/374 (7%)
Query: 46 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105
D TF V Y+ ++ IG+GA G+V +A + + VAIKK+ F T+AKR REL +
Sbjct: 55 DSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVL 114
Query: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165
+K H NII++ ++ P EF+ VY+V++LM+++L Q+I L E + Y LYQ
Sbjct: 115 MKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI--QMELDHERMSYLLYQ 172
Query: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225
+L G+K++HSA +IHRDLKPSN++V +C LKI DFG+AR TS + MT YV TR
Sbjct: 173 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTS-----FMMTPYVVTR 227
Query: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAV 285
+YRAPE++L + Y + +D+WSVGCI GEM+ + LFPG++Y+ Q ++ LGTP P
Sbjct: 228 YYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEF 286
Query: 286 IQAVGAERVRAYIQSLPPRQPVPWETVYPGA------------DRQALSLLGRMLRFEPS 333
++ + VR Y+++ P + + ++P + QA LL +ML +P+
Sbjct: 287 MKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPA 345
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPP--FDFAFDREALTRERIKEAIVAEIEDFHAR 391
RIS AL+HP++ ++DP E + PP +D D T E KE I E+ + +
Sbjct: 346 KRISVDDALQHPYINVWYDP-AEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEK 404
Query: 392 -REGIRQQIRFQPS 404
+ G+ ++ QPS
Sbjct: 405 TKNGV---VKGQPS 415
>gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo
sapiens]
Length = 464
Score = 243 bits (620), Expect = 5e-64
Identities = 144/374 (38%), Positives = 221/374 (59%), Gaps = 28/374 (7%)
Query: 46 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105
D TF V Y+ ++ IG+GA G+V +A + + VAIKK+ F T+AKR REL +
Sbjct: 55 DSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVL 114
Query: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165
+K H NII++ ++ P EF+ VY+V++LM+++L Q+I L E + Y LYQ
Sbjct: 115 MKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI--QMELDHERMSYLLYQ 172
Query: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225
+L G+K++HSA +IHRDLKPSN++V +C LKI DFG+AR TS + MT YV TR
Sbjct: 173 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTS-----FMMTPYVVTR 227
Query: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAV 285
+YRAPE++L + Y + +D+WSVGCI GEM+ + LFPG++Y+ Q ++ LGTP P
Sbjct: 228 YYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEF 286
Query: 286 IQAVGAERVRAYIQSLPPRQPVPWETVYPGA------------DRQALSLLGRMLRFEPS 333
++ + VR Y+++ P + + ++P + QA LL +ML +P+
Sbjct: 287 MKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPA 345
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPP--FDFAFDREALTRERIKEAIVAEIEDFHAR 391
RIS AL+HP++ ++DP E + PP +D D T E KE I E+ + +
Sbjct: 346 KRISVDDALQHPYINVWYDP-AEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEK 404
Query: 392 -REGIRQQIRFQPS 404
+ G+ ++ QPS
Sbjct: 405 TKNGV---VKGQPS 415
>gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo
sapiens]
Length = 426
Score = 243 bits (620), Expect = 5e-64
Identities = 144/374 (38%), Positives = 221/374 (59%), Gaps = 28/374 (7%)
Query: 46 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105
D TF V Y+ ++ IG+GA G+V +A + + VAIKK+ F T+AKR REL +
Sbjct: 17 DSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVL 76
Query: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165
+K H NII++ ++ P EF+ VY+V++LM+++L Q+I L E + Y LYQ
Sbjct: 77 MKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI--QMELDHERMSYLLYQ 134
Query: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225
+L G+K++HSA +IHRDLKPSN++V +C LKI DFG+AR TS + MT YV TR
Sbjct: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTS-----FMMTPYVVTR 189
Query: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAV 285
+YRAPE++L + Y + +D+WSVGCI GEM+ + LFPG++Y+ Q ++ LGTP P
Sbjct: 190 YYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEF 248
Query: 286 IQAVGAERVRAYIQSLPPRQPVPWETVYPGA------------DRQALSLLGRMLRFEPS 333
++ + VR Y+++ P + + ++P + QA LL +ML +P+
Sbjct: 249 MKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPA 307
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPP--FDFAFDREALTRERIKEAIVAEIEDFHAR 391
RIS AL+HP++ ++DP E + PP +D D T E KE I E+ + +
Sbjct: 308 KRISVDDALQHPYINVWYDP-AEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEK 366
Query: 392 -REGIRQQIRFQPS 404
+ G+ ++ QPS
Sbjct: 367 TKNGV---VKGQPS 377
>gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]
Length = 721
Score = 228 bits (582), Expect = 1e-59
Identities = 138/330 (41%), Positives = 197/330 (59%), Gaps = 26/330 (7%)
Query: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTN---AKRTLRELKI 105
FD+G Y ++ +G G G+V SA ++VAIKKI V+T+ K LRE+KI
Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKI-----VLTDPQSVKHALREIKI 68
Query: 106 LKHFKHDNIIAIKDILRP-----TVPYG---EFKSVYVVLDLMESDLHQIIHSSQPLTLE 157
++ HDNI+ + +IL P T G E SVY+V + ME+DL ++ PL E
Sbjct: 69 IRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQG-PLLEE 127
Query: 158 HVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVN-ENCELKIGDFGMARGLCTSPAEHQY 216
H R F+YQLLRGLKY+HSA V+HRDLKP+NL +N E+ LKIGDFG+AR + H+
Sbjct: 128 HARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLAR-IMDPHYSHKG 186
Query: 217 FMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMM 276
++E + T+WYR+P L+LS + YT+AID+W+ GCIF EML + LF G + + Q+QLI+
Sbjct: 187 HLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILE 246
Query: 277 VLGTPSPAVIQAVGAER---VRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPS 333
+ P V + E + YI++ P + PG R+AL L ++L F P
Sbjct: 247 SI----PVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFSPM 302
Query: 334 ARISAAAALRHPFLAKYHDPDDEPDCAPPF 363
R++A AL HP+++ Y P DEP + PF
Sbjct: 303 DRLTAEEALSHPYMSIYSFPMDEPISSHPF 332
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,337,778
Number of Sequences: 37866
Number of extensions: 3204065
Number of successful extensions: 95568
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2028
Number of HSP's successfully gapped in prelim test: 2273
Number of HSP's that attempted gapping in prelim test: 21829
Number of HSP's gapped (non-prelim): 33123
length of query: 816
length of database: 18,247,518
effective HSP length: 111
effective length of query: 705
effective length of database: 14,044,392
effective search space: 9901296360
effective search space used: 9901296360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.