Search of human proteins with 208431776

Search of human proteins with 208431776

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 4 [Homo sapiens]
         (500 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I, ...  1008   0.0  
gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, al...   981   0.0  
gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I, ...   967   0.0  
gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I, ...   904   0.0  
gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I, g...   657   0.0  
gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, be...   591   e-169
gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, b...   170   2e-42
gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, a...   164   2e-40
gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,...   163   4e-40
gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,...   163   4e-40
gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,...   156   4e-38
gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,...   132   6e-31
gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1 is...   104   2e-22
gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1 iso...    54   3e-07
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ...    53   7e-07
gi|18105056 vacuolar protein sorting 33A [Homo sapiens]                34   0.35 
gi|31317261 tafazzin isoform 3 [Homo sapiens]                          33   0.79 
gi|222537754 hypothetical protein LOC375337 [Homo sapiens]             32   1.0  
gi|4507371 tafazzin isoform 1 [Homo sapiens]                           32   1.0  
gi|193083221 mast cell immunoreceptor signal transducer [Homo sa...    30   3.9  
gi|221139926 NHS-like 1 [Homo sapiens]                                 30   6.7  
gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo ...    29   8.7  
gi|14277690 hypothetical protein LOC9750 isoform 2 [Homo sapiens]      29   8.7  

>gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 4 [Homo sapiens]
          Length = 500

 Score = 1008 bits (2605), Expect = 0.0
 Identities = 500/500 (100%), Positives = 500/500 (100%)

Query: 1   MASASSGPSSSVGFSSFDPAVPSCTLSSASGIKRPMASEVPYASGMPIKKIGHRSVDSSG 60
           MASASSGPSSSVGFSSFDPAVPSCTLSSASGIKRPMASEVPYASGMPIKKIGHRSVDSSG
Sbjct: 1   MASASSGPSSSVGFSSFDPAVPSCTLSSASGIKRPMASEVPYASGMPIKKIGHRSVDSSG 60

Query: 61  ETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHH 120
           ETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHH
Sbjct: 61  ETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHH 120

Query: 121 YNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFII 180
           YNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFII
Sbjct: 121 YNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFII 180

Query: 181 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVK 240
           KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVK
Sbjct: 181 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVK 240

Query: 241 MHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCL 300
           MHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCL
Sbjct: 241 MHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCL 300

Query: 301 VLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARR 360
           VLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARR
Sbjct: 301 VLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARR 360

Query: 361 GGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHR 420
           GGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHR
Sbjct: 361 GGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHR 420

Query: 421 PGFYAERFQRFMCNTVFKKIPCVHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGETLQ 480
           PGFYAERFQRFMCNTVFKKIPCVHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGETLQ
Sbjct: 421 PGFYAERFQRFMCNTVFKKIPCVHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGETLQ 480

Query: 481 MLTTSTTLEKLEVAESEFTH 500
           MLTTSTTLEKLEVAESEFTH
Sbjct: 481 MLTTSTTLEKLEVAESEFTH 500


>gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
           isoform 2 [Homo sapiens]
          Length = 549

 Score =  981 bits (2535), Expect = 0.0
 Identities = 499/549 (90%), Positives = 499/549 (90%), Gaps = 49/549 (8%)

Query: 1   MASASSGPSSSVGFSSFDPAVPSCTLSSASGIKRPMASEVPYASGMPIKKIGHRSVDSSG 60
           MASASSGPSSSVGFSSFDPAVPSCTLSSASGIKRPMASEVPYASGMPIKKIGHRSVDSSG
Sbjct: 1   MASASSGPSSSVGFSSFDPAVPSCTLSSASGIKRPMASEVPYASGMPIKKIGHRSVDSSG 60

Query: 61  ETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHH 120
           ETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHH
Sbjct: 61  ETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHH 120

Query: 121 YNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFII 180
           YNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFII
Sbjct: 121 YNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFII 180

Query: 181 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVK 240
           KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVK
Sbjct: 181 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVK 240

Query: 241 MHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCL 300
           MHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCL
Sbjct: 241 MHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCL 300

Query: 301 VLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARR 360
           VLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARR
Sbjct: 301 VLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARR 360

Query: 361 GGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHR 420
           GGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHR
Sbjct: 361 GGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHR 420

Query: 421 PGFYAERFQRFMCNTVFKKIPC-------------------------------------- 442
           PGFYAERFQRFMCNTVFKKIP                                       
Sbjct: 421 PGFYAERFQRFMCNTVFKKIPLKPSPSKKFRSGSSFSRRAGSSGNSCITYQPSVSGEHKA 480

Query: 443 -----------VHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGETLQMLTTSTTLEKL 491
                      VHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGETLQMLTTSTTLEKL
Sbjct: 481 QVTTKAEVEPGVHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGETLQMLTTSTTLEKL 540

Query: 492 EVAESEFTH 500
           EVAESEFTH
Sbjct: 541 EVAESEFTH 549


>gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 1 [Homo sapiens]
          Length = 562

 Score =  967 bits (2500), Expect = 0.0
 Identities = 499/562 (88%), Positives = 499/562 (88%), Gaps = 62/562 (11%)

Query: 1   MASASSGPSSSVGFSSFDPAVPSCTLSSA-SGIKRPMASEV------------PYASGMP 47
           MASASSGPSSSVGFSSFDPAVPSCTLSSA SGIKRPMASEV            PYASGMP
Sbjct: 1   MASASSGPSSSVGFSSFDPAVPSCTLSSAASGIKRPMASEVLEARQDSYISLVPYASGMP 60

Query: 48  IKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIF 107
           IKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIF
Sbjct: 61  IKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIF 120

Query: 108 FPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASG 167
           FPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASG
Sbjct: 121 FPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASG 180

Query: 168 SLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIR 227
           SLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIR
Sbjct: 181 SLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIR 240

Query: 228 IVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADM 287
           IVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADM
Sbjct: 241 IVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADM 300

Query: 288 YNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALY 347
           YNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALY
Sbjct: 301 YNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALY 360

Query: 348 STAMESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWK 407
           STAMESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWK
Sbjct: 361 STAMESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWK 420

Query: 408 ALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPC------------------------- 442
           ALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIP                          
Sbjct: 421 ALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPLKPSPSKKFRSGSSFSRRAGSSGNSC 480

Query: 443 ------------------------VHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGET 478
                                   VHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGET
Sbjct: 481 ITYQPSVSGEHKAQVTTKAEVEPGVHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGET 540

Query: 479 LQMLTTSTTLEKLEVAESEFTH 500
           LQMLTTSTTLEKLEVAESEFTH
Sbjct: 541 LQMLTTSTTLEKLEVAESEFTH 562


>gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 3 [Homo sapiens]
          Length = 522

 Score =  904 bits (2337), Expect = 0.0
 Identities = 470/550 (85%), Positives = 471/550 (85%), Gaps = 78/550 (14%)

Query: 1   MASASSGPSSSVGFSSFDPAVPSCTLSSA-SGIKRPMASEVPYASGMPIKKIGHRSVDSS 59
           MASASSGPSSSVGFSSFDPAVPSCTLSSA SGIKRPMASEVPYASGMPIKKIGHRSVDSS
Sbjct: 1   MASASSGPSSSVGFSSFDPAVPSCTLSSAASGIKRPMASEVPYASGMPIKKIGHRSVDSS 60

Query: 60  GETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAH 119
           GETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAH
Sbjct: 61  GETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAH 120

Query: 120 HYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFI 179
           HYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFI
Sbjct: 121 HYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFI 180

Query: 180 IKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSV 239
           IKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSV
Sbjct: 181 IKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSV 240

Query: 240 KMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDC 299
           KMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDC
Sbjct: 241 KMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDC 300

Query: 300 LVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEAR 359
           LVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEAR
Sbjct: 301 LVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEAR 360

Query: 360 RGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVH 419
           RGGTMETDD                            +FVKKLEHSWKALVHDGDTVSVH
Sbjct: 361 RGGTMETDD----------------------------QFVKKLEHSWKALVHDGDTVSVH 392

Query: 420 RPGFYAERFQRFMCNTVFKKIPC------------------------------------- 442
           RPGFYAERFQRFMCNTVFKKIP                                      
Sbjct: 393 RPGFYAERFQRFMCNTVFKKIPLKPSPSKKFRSGSSFSRRAGSSGNSCITYQPSVSGEHK 452

Query: 443 ------------VHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGETLQMLTTSTTLEK 490
                       VHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGETLQMLTTSTTLEK
Sbjct: 453 AQVTTKAEVEPGVHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGETLQMLTTSTTLEK 512

Query: 491 LEVAESEFTH 500
           LEVAESEFTH
Sbjct: 513 LEVAESEFTH 522


>gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I,
           gamma [Homo sapiens]
          Length = 668

 Score =  657 bits (1694), Expect = 0.0
 Identities = 318/391 (81%), Positives = 354/391 (90%)

Query: 49  KKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFF 108
           KK+GHR VD+SGETTYKKTTSS LKGAIQLGI +TVG LS+KPERDVLMQDFYVVESIFF
Sbjct: 56  KKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFF 115

Query: 109 PSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGS 168
           PSEGSNLTPAHH+ DFRFKTYAPVAFRYFRELFGIRPDDYLYSLC+EPLIEL + GASGS
Sbjct: 116 PSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGS 175

Query: 169 LFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRI 228
           LFYV+SDDEFIIKTV HKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQ+GGKNIR+
Sbjct: 176 LFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRV 235

Query: 229 VVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMY 288
           VVMNN+LPR VKMH+K+DLKGSTYKRRAS+KE+EK  PT+KDLDF+QD+P+GL LDAD +
Sbjct: 236 VVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTF 295

Query: 289 NALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYS 348
           +AL KTLQRDCLVL+SFKIMDYSLL+ +HNID  +RE  +   Q + D +RP  QKALYS
Sbjct: 296 SALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYS 355

Query: 349 TAMESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKA 408
           TAMESIQG A RG  +E+DD MGGIPA N +GERLLL+IGIIDILQSYRF+KKLEH+WKA
Sbjct: 356 TAMESIQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKA 415

Query: 409 LVHDGDTVSVHRPGFYAERFQRFMCNTVFKK 439
           LVHDGDTVSVHRP FYAERF +FM NTVF+K
Sbjct: 416 LVHDGDTVSVHRPSFYAERFFKFMSNTVFRK 446


>gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
           isoform 2 [Homo sapiens]
          Length = 540

 Score =  591 bits (1524), Expect = e-169
 Identities = 290/382 (75%), Positives = 331/382 (86%), Gaps = 2/382 (0%)

Query: 61  ETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHH 120
           E TYKKT SSA+KGAIQLGI +TVG+L++KPERDVLMQDFYVVES+F PSEGSNLTPAHH
Sbjct: 18  EKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHH 77

Query: 121 YNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFII 180
           Y DFRFKTYAP+AFRYFRELFGI+PDDYLYS+CSEPLIEL + GASGSLF+V+SDDEFII
Sbjct: 78  YPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFII 137

Query: 181 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVK 240
           KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYC+Q+GG NIRIVVMNN+LPRS++
Sbjct: 138 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRSMR 197

Query: 241 MHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCL 300
           MH  YDLKGSTYKRRAS+KEREK  PTFKDLDFLQD+ +GL+ D + YNAL KTLQRDC 
Sbjct: 198 MHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCR 257

Query: 301 VLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARR 360
           VL+SFKIMDYSLL+ IH +DH+ +E      Q   D +R   QK LYSTAMESIQG  + 
Sbjct: 258 VLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKS 317

Query: 361 GGTM--ETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSV 418
           G  +  E  D MGGIPA++ +GE+LLL++GIIDILQSYR +KKLEHSWKALV+DGDTVSV
Sbjct: 318 GDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSV 377

Query: 419 HRPGFYAERFQRFMCNTVFKKI 440
           HRP FYA+RF +FM + VFKKI
Sbjct: 378 HRPSFYADRFLKFMNSRVFKKI 399


>gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, beta
           [Homo sapiens]
          Length = 416

 Score =  170 bits (431), Expect = 2e-42
 Identities = 125/383 (32%), Positives = 185/383 (48%), Gaps = 25/383 (6%)

Query: 69  SSALKGAIQLGITHTVGSLSTKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHYN 122
           S  +   +  G+ HT+  LS  P   +LM D +       V++  F  E  NL      +
Sbjct: 39  SEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKE--NLP-----S 91

Query: 123 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKT 182
            F+FK Y P+ FR  RE FGI   DY  S+     I   S G  G+ F  + D  F+IKT
Sbjct: 92  RFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKT 151

Query: 183 VQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKM 241
           V  ++   +  +L  Y+  + + +  TLLP+F G+Y +   G    +VV  N+    + +
Sbjct: 152 VSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTV 211

Query: 242 HIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLV 301
           H KYDLKGST  R AS KE+ K LPTFKD DFL +    L +  +      + L+RD   
Sbjct: 212 HRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNE-GQKLHVGEESKKNFLEKLKRDVEF 270

Query: 302 LQSFKIMDYSLLMSIHNIDHAQREPLS----SETQYSVDTRRPAPQKALYSTAMES---I 354
           L   KIMDYSLL+ IH++D A++E +     +E +   +          Y T  +S   +
Sbjct: 271 LAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNL 330

Query: 355 QGEARRGGTMETDDHMG--GIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHD 412
               R  G  E D  +    + +  S  ++ + ++ IIDIL  Y   KK  H+ K + H 
Sbjct: 331 LSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHG 390

Query: 413 -GDTVSVHRPGFYAERFQRFMCN 434
            G  +S   P  Y++RF  FM N
Sbjct: 391 AGAEISTVNPEQYSKRFNEFMSN 413


>gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II,
           alpha [Homo sapiens]
          Length = 406

 Score =  164 bits (414), Expect = 2e-40
 Identities = 115/383 (30%), Positives = 185/383 (48%), Gaps = 34/383 (8%)

Query: 69  SSALKGAIQLGITHTVGSLSTKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHYN 122
           S  L   +  G+ H++  LS      +LM D +       V++  F  E     P+H   
Sbjct: 34  SDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENM---PSH--- 87

Query: 123 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKT 182
            F+FK Y P+ FR  RE FGI   D+  SL     +   S   SG+ F+ S D  +IIKT
Sbjct: 88  -FKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKT 146

Query: 183 VQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKM 241
           +  ++   +  +L  Y+  + + +  TLLP+F G+Y +   G  I ++V  N+    + +
Sbjct: 147 ITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSV 206

Query: 242 HIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLV 301
           + KYDLKGST  R AS KE+ K LPT KD DF+ +    +++D +      + L++D   
Sbjct: 207 YRKYDLKGSTVAREASDKEKAKELPTLKDNDFINE-GQKIYIDDNNKKVFLEKLKKDVEF 265

Query: 302 LQSFKIMDYSLLMSIHNIDHAQREPL-----------SSETQYSVDTRRPAPQKALYSTA 350
           L   K+MDYSLL+ IH+++ A++E +            S+  + V T   +P   L S+ 
Sbjct: 266 LAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSS- 324

Query: 351 MESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALV 410
                      G  + +  + GI    +   + + ++ IIDIL  Y   KK  H+ K + 
Sbjct: 325 ------PPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVK 378

Query: 411 HD-GDTVSVHRPGFYAERFQRFM 432
           H  G  +S   P  Y++RF  F+
Sbjct: 379 HGAGAEISTVNPEQYSKRFLDFI 401


>gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform a [Homo sapiens]
          Length = 421

 Score =  163 bits (412), Expect = 4e-40
 Identities = 125/381 (32%), Positives = 182/381 (47%), Gaps = 27/381 (7%)

Query: 72  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 127
           L G    G+ H++  LS  P   +L+ D +   S    +       NL P+H    F+FK
Sbjct: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101

Query: 128 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 187
            Y P  FR  R+ FGI   DYL SL   P  E  S G+ G  F +S D   +IK V  ++
Sbjct: 102 EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSED 158

Query: 188 AEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYD 246
              +   L  Y+  + + +  TLLP+F G+Y V    ++  ++VM N+    + +H KYD
Sbjct: 159 IADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218

Query: 247 LKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFK 306
           LKGS   R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   K
Sbjct: 219 LKGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLK 277

Query: 307 IMDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG--- 356
           IMDYSLL+ IH+I       + A      SE         P      Y T+ E I G   
Sbjct: 278 IMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIH 337

Query: 357 EARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-G 413
             R  G  E +  +     R+++G  ++ + ++G+IDIL  Y   KK  H+ K + H  G
Sbjct: 338 SHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397

Query: 414 DTVSVHRPGFYAERFQRFMCN 434
             +S   P  YA+RF  F+ N
Sbjct: 398 AEISTVHPEQYAKRFLDFITN 418


>gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform a [Homo sapiens]
          Length = 421

 Score =  163 bits (412), Expect = 4e-40
 Identities = 125/381 (32%), Positives = 182/381 (47%), Gaps = 27/381 (7%)

Query: 72  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 127
           L G    G+ H++  LS  P   +L+ D +   S    +       NL P+H    F+FK
Sbjct: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101

Query: 128 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 187
            Y P  FR  R+ FGI   DYL SL   P  E  S G+ G  F +S D   +IK V  ++
Sbjct: 102 EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSED 158

Query: 188 AEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYD 246
              +   L  Y+  + + +  TLLP+F G+Y V    ++  ++VM N+    + +H KYD
Sbjct: 159 IADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218

Query: 247 LKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFK 306
           LKGS   R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   K
Sbjct: 219 LKGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLK 277

Query: 307 IMDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG--- 356
           IMDYSLL+ IH+I       + A      SE         P      Y T+ E I G   
Sbjct: 278 IMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIH 337

Query: 357 EARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-G 413
             R  G  E +  +     R+++G  ++ + ++G+IDIL  Y   KK  H+ K + H  G
Sbjct: 338 SHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397

Query: 414 DTVSVHRPGFYAERFQRFMCN 434
             +S   P  YA+RF  F+ N
Sbjct: 398 AEISTVHPEQYAKRFLDFITN 418


>gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform b [Homo sapiens]
          Length = 403

 Score =  156 bits (395), Expect = 4e-38
 Identities = 119/377 (31%), Positives = 174/377 (46%), Gaps = 37/377 (9%)

Query: 72  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAP 131
           L G    G+ H++  LS  P   +L+ D +   S                   + K Y P
Sbjct: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASS-------------------KIKEYCP 87

Query: 132 VAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFL 191
             FR  R+ FGI   DYL SL   P  E  S G+ G  F +S D   +IK V  ++   +
Sbjct: 88  QVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADM 144

Query: 192 QKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGS 250
              L  Y+  + + +  TLLP+F G+Y V    ++  ++VM N+    + +H KYDLKGS
Sbjct: 145 HSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGS 204

Query: 251 TYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDY 310
              R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   KIMDY
Sbjct: 205 LVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDY 263

Query: 311 SLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG---EARR 360
           SLL+ IH+I       + A      SE         P      Y T+ E I G     R 
Sbjct: 264 SLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRP 323

Query: 361 GGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-GDTVS 417
            G  E +  +     R+++G  ++ + ++G+IDIL  Y   KK  H+ K + H  G  +S
Sbjct: 324 LGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEIS 383

Query: 418 VHRPGFYAERFQRFMCN 434
              P  YA+RF  F+ N
Sbjct: 384 TVHPEQYAKRFLDFITN 400


>gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform c [Homo sapiens]
          Length = 373

 Score =  132 bits (333), Expect = 6e-31
 Identities = 113/380 (29%), Positives = 162/380 (42%), Gaps = 73/380 (19%)

Query: 72  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 127
           L G    G+ H++  LS  P   +L+ D +   S    +       NL P+H    F+FK
Sbjct: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101

Query: 128 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 187
            Y P  FR  R+ FGI   DYLY                            I+K      
Sbjct: 102 EYCPQVFRNLRDRFGIDDQDYLY----------------------------IVKC----- 128

Query: 188 AEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDL 247
                            +  TLLP+F G+Y V    ++  ++VM N+    + +H KYDL
Sbjct: 129 -----------------HGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDL 171

Query: 248 KGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKI 307
           KGS   R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   KI
Sbjct: 172 KGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLKI 230

Query: 308 MDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG---E 357
           MDYSLL+ IH+I       + A      SE         P      Y T+ E I G    
Sbjct: 231 MDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHS 290

Query: 358 ARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-GD 414
            R  G  E +  +     R+++G  ++ + ++G+IDIL  Y   KK  H+ K + H  G 
Sbjct: 291 HRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGA 350

Query: 415 TVSVHRPGFYAERFQRFMCN 434
            +S   P  YA+RF  F+ N
Sbjct: 351 EISTVHPEQYAKRFLDFITN 370


>gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1
           isoform 1 [Homo sapiens]
          Length = 394

 Score =  104 bits (259), Expect = 2e-22
 Identities = 85/322 (26%), Positives = 143/322 (44%), Gaps = 34/322 (10%)

Query: 115 LTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLC-SEPLIELCSSGASGSLFYVS 173
           LT  H    F   T A  AF + R   G+  +DY  +L    P ++  S+  S + F++S
Sbjct: 88  LTQVHE--GFELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLS 145

Query: 174 SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAG-GKNIRIVVMN 232
            D  F +KT   +E + L   LP Y  +L ++P +LL +  G++ ++   GK    +VM 
Sbjct: 146 HDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHSLLARLLGVHSLRVDRGKKTYFIVMQ 205

Query: 233 NLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLP-TFKDLDFLQDIPDGLFLDADMYNA- 290
           ++   + ++  +YD+KG    R         PL    KDL+F      G  ++     + 
Sbjct: 206 SVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF-----QGKTINLGPQRSW 260

Query: 291 LCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTA 350
             + ++ D   L+   ++DYSLL++   +   +R P SS                ++ TA
Sbjct: 261 FLRQMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSS---------------LIFRTA 305

Query: 351 MESIQG-----EARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHS 405
             S+QG     E+R        D    +   +   +R   ++G++D+   Y   K+LEH 
Sbjct: 306 -RSVQGAQSPEESRAQNRRLLPDAPNALHILDGPEQR--YFLGVVDLATVYGLRKRLEHL 362

Query: 406 WKALVHDGDTVSVHRPGFYAER 427
           WK L + G T S   P  YA R
Sbjct: 363 WKTLRYPGRTFSTVSPARYARR 384


>gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1
           isoform 2 [Homo sapiens]
          Length = 191

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 49/191 (25%), Positives = 79/191 (41%), Gaps = 30/191 (15%)

Query: 244 KYDLKGSTYKRRASQKEREKPLP-TFKDLDFLQDIPDGLFLDADMYNA-LCKTLQRDCLV 301
           +YD+KG    R         PL    KDL+F      G  ++     +   + ++ D   
Sbjct: 14  RYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF-----QGKTINLGPQRSWFLRQMELDTTF 68

Query: 302 LQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG----- 356
           L+   ++DYSLL++   +   +R P SS                ++ TA  S+QG     
Sbjct: 69  LRELNVLDYSLLIAFQRLHEDERGPGSS---------------LIFRTA-RSVQGAQSPE 112

Query: 357 EARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTV 416
           E+R        D    +   +   +R   ++G++D+   Y   K+LEH WK L + G T 
Sbjct: 113 ESRAQNRRLLPDAPNALHILDGPEQRY--FLGVVDLATVYGLRKRLEHLWKTLRYPGRTF 170

Query: 417 SVHRPGFYAER 427
           S   P  YA R
Sbjct: 171 STVSPARYARR 181


>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
            isoform 2 [Homo sapiens]
          Length = 2098

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 55/204 (26%), Positives = 86/204 (42%), Gaps = 15/204 (7%)

Query: 124  FRFKTYAPVAFRYFRE-LFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKT 182
            F  + Y    F   RE +     +D++ SL      +    G SG+ FY + DD FI+K 
Sbjct: 1820 FYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQ-ARGGKSGAAFYATEDDRFILKQ 1878

Query: 183  VQHKEAEFLQKLLPGYYMNL----NQNPRTLLPKFYGLYCV------QAGGKNIRIVVMN 232
            +   E +      P Y+  +     Q   T L K  G+Y +          K + ++VM 
Sbjct: 1879 MPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVME 1938

Query: 233  NLLPRSVKMHIKYDLKGSTYKRRA-SQKEREKPLPTFKDLDFLQDIPDG-LFLDADMYNA 290
            NL     KM   +DLKGS   R   +   +E       D + L+ + D  L++ +     
Sbjct: 1939 NLF-YGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAV 1997

Query: 291  LCKTLQRDCLVLQSFKIMDYSLLM 314
            L  ++  D   L S  I+DYSLL+
Sbjct: 1998 LRTSIHSDSHFLSSHLIIDYSLLV 2021


>gi|18105056 vacuolar protein sorting 33A [Homo sapiens]
          Length = 596

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 342 PQKALYSTAMESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKK 401
           P+  L     E++  E RRG T   D H+  +P R+   E+ L  +G++       F+ +
Sbjct: 85  PRLELMDIIAENVLSEDRRGPTR--DFHILFVPRRSLLCEQRLKDLGVLG-----SFIHR 137

Query: 402 LEHSWKALVHDGDTVSVHRPGFYAE 426
            E+S   +  DGD +S+   G + E
Sbjct: 138 EEYSLDLIPFDGDLLSMESEGAFKE 162


>gi|31317261 tafazzin isoform 3 [Homo sapiens]
          Length = 278

 Score = 32.7 bits (73), Expect = 0.79
 Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 18/105 (17%)

Query: 352 ESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVH 411
           E  Q E    G ++T  HM G   R  KG+ +  Y   +D +     ++KL H       
Sbjct: 126 EFFQAENEGKGVLDTGRHMPGAGKRREKGDGV--YQKGMDFI-----LEKLNH------- 171

Query: 412 DGDTVSVHRPGFYAERFQRFMCNTVFKKIPCVHLGRPDVLPQTPP 456
            GD V +   G           N +   +P  H+G  DVLP +PP
Sbjct: 172 -GDWVHIFPEGI-GRLIAECHLNPII--LPLWHVGMNDVLPNSPP 212


>gi|222537754 hypothetical protein LOC375337 [Homo sapiens]
          Length = 1692

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 11/46 (23%), Positives = 29/46 (63%)

Query: 271  LDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDYSLLMSI 316
            +++ +  P G++ D  + N L  +L + CL+ + F+I++ S+++ +
Sbjct: 1150 MEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMVKM 1195


>gi|4507371 tafazzin isoform 1 [Homo sapiens]
          Length = 292

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 26/116 (22%)

Query: 352 ESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVH 411
           E  Q E    G ++T  HM G   R  KG+ +  Y   +D +     ++KL H       
Sbjct: 126 EFFQAENEGKGVLDTGRHMPGAGKRREKGDGV--YQKGMDFI-----LEKLNH------- 171

Query: 412 DGDTVSVHRPGFY--AERFQRFM---------CNTVFKKIPCVHLGRPDVLPQTPP 456
            GD V +   G    +  F RF          C+     +P  H+G  DVLP +PP
Sbjct: 172 -GDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPP 226


>gi|193083221 mast cell immunoreceptor signal transducer [Homo
           sapiens]
          Length = 428

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 307 IMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRP--APQKALYSTAMESIQGEARRGGTM 364
           + D S ++    + H QR+P S+    + +T+    A   + ++T+  S+Q    RGG  
Sbjct: 205 LRDLSEVLEAEKVPHNQRKPESTHLLENQNTQEIPLAISSSSFTTSNHSVQNRDHRGGMQ 264

Query: 365 ETDDHMGGIPARNSKGERLLLY 386
                    PA  S  E +L Y
Sbjct: 265 PCSPQRCQPPASCSPHENILPY 286


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 447 RPDVLPQTPPLEEISEGSPIP-DPSFSPLVGETL 479
           R   LP  PP+ + S+GSP+P  P F P   E L
Sbjct: 946 RSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEAL 979


>gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 666

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 17/53 (32%), Positives = 33/53 (62%), Gaps = 2/53 (3%)

Query: 246 DLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMY-NALCKTLQR 297
           DL+   + +  S+ E  +P P  K LD++QD   G+F +A +Y +++ ++L+R
Sbjct: 284 DLENEPWYKFFSELEFGRPPPK-KPLDYVQDHSSGVFNEASLYQSSIDRSLER 335


>gi|14277690 hypothetical protein LOC9750 isoform 2 [Homo sapiens]
          Length = 591

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 14/36 (38%), Positives = 20/36 (55%), Gaps = 1/36 (2%)

Query: 248 KGSTYKRRASQKEREKP-LPTFKDLDFLQDIPDGLF 282
           K +  +RR S   +  P  PTFKD  F  ++PD +F
Sbjct: 332 KAAALQRRMSMYSQGTPETPTFKDHSFFSNLPDDIF 367


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,861,044
Number of Sequences: 37866
Number of extensions: 942634
Number of successful extensions: 2527
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2474
Number of HSP's gapped (non-prelim): 34
length of query: 500
length of database: 18,247,518
effective HSP length: 106
effective length of query: 394
effective length of database: 14,233,722
effective search space: 5608086468
effective search space used: 5608086468
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.