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Search of human proteins with 20544129
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
sapiens]
(703 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 1395 0.0
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 608 e-174
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] 593 e-169
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 566 e-161
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi... 558 e-159
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi... 541 e-153
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi... 439 e-123
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi... 332 7e-91
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom... 314 2e-85
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po... 305 7e-83
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 295 7e-80
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 285 1e-76
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo... 285 1e-76
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 258 1e-68
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 241 2e-63
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 241 2e-63
gi|166851804 tudor domain containing 9 [Homo sapiens] 211 2e-54
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 207 2e-53
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 180 4e-45
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 174 2e-43
gi|38505213 YTH domain containing 2 [Homo sapiens] 159 8e-39
gi|226492499 septin 12 isoform 1 [Homo sapiens] 34 0.53
gi|226492421 septin 12 isoform 2 [Homo sapiens] 33 0.69
gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens] 33 0.90
gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens] 33 0.90
gi|116734710 ATP-binding cassette, sub-family A member 3 [Homo s... 32 2.6
gi|5729980 phosphomevalonate kinase [Homo sapiens] 31 3.4
gi|153945836 endothelin converting enzyme 2 isoform E [Homo sapi... 31 3.4
gi|153945771 endothelin converting enzyme 2 isoform D [Homo sapi... 31 3.4
gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens] 31 3.4
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
sapiens]
Length = 703
Score = 1395 bits (3611), Expect = 0.0
Identities = 703/703 (100%), Positives = 703/703 (100%)
Query: 1 MAAPVGPVKFWRPGTEGPGVSISEERQSLAENSGTTVVYNPYAALSIEQQRQKLPVFKLR 60
MAAPVGPVKFWRPGTEGPGVSISEERQSLAENSGTTVVYNPYAALSIEQQRQKLPVFKLR
Sbjct: 1 MAAPVGPVKFWRPGTEGPGVSISEERQSLAENSGTTVVYNPYAALSIEQQRQKLPVFKLR 60
Query: 61 NHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRV 120
NHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRV
Sbjct: 61 NHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRV 120
Query: 121 AEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHE 180
AEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHE
Sbjct: 121 AEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHE 180
Query: 181 RTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEG 240
RTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEG
Sbjct: 181 RTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEG 240
Query: 241 RTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARA 300
RTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARA
Sbjct: 241 RTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARA 300
Query: 301 LARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDC 360
LARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDC
Sbjct: 301 LARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDC 360
Query: 361 GFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVP 420
GFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVP
Sbjct: 361 GFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVP 420
Query: 421 EMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLG 480
EMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLG
Sbjct: 421 EMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLG 480
Query: 481 MRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAV 540
MRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAV
Sbjct: 481 MRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAV 540
Query: 541 EEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSE 600
EEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSE
Sbjct: 541 EEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSE 600
Query: 601 GDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQ 660
GDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQ
Sbjct: 601 GDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQ 660
Query: 661 TSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDP 703
TSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDP
Sbjct: 661 TSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDP 703
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 608 bits (1568), Expect = e-174
Identities = 321/714 (44%), Positives = 471/714 (65%), Gaps = 32/714 (4%)
Query: 4 PVGPVKFW---RPGTEGPGVSISEERQSLAENS----------GTTVVYNPYAALSIEQQ 50
P+G K W P EG ++ + + N G Y +SI +Q
Sbjct: 502 PMGLNKHWVDPLPDAEGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQMSILEQ 561
Query: 51 RQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRR 110
R+ LP++KL+ ++ + + Q ++++GETG GK+TQI QYLAEAG+T+ G++ G TQPRR
Sbjct: 562 RESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKI-GCTQPRR 620
Query: 111 VAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKY 170
VAA++VA RV+EE G LG EVGY IRF+DCT T IK++TDGML+RE ++DP LT+Y
Sbjct: 621 VAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSP-ETVIKYMTDGMLLRECLIDPDLTQY 679
Query: 171 SVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPAR 230
++IMLDEAHERT++TD+ GLLKK +KR D++LIV SATLDA KF +F +
Sbjct: 680 AIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYE-------- 731
Query: 231 DTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETV 290
I T+ GRT+PV+I Y + P DY+ +++ TV++IH TE GD+L FLTGQEE++T
Sbjct: 732 --APIFTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTA 789
Query: 291 VSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSIT 350
+L E+ ++L + L +LP+Y+ LPS Q ++F+ RKV++ATN+AETS+T
Sbjct: 790 CEILYERMKSLGPDVPE--LIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLT 847
Query: 351 ISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEA 410
I GI YV+D GFVK + YN +T I+ LVV P+SQA A QRAGR GR+ GKCYRLYTE A
Sbjct: 848 IDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERA 907
Query: 411 F-DKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGL 469
+ D++ + VPE+QR+NLA +L LKA+GI+++L F FM PP ++++ A+E LY LG L
Sbjct: 908 YRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGAL 967
Query: 470 DKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKS 529
D + LT LG R+AEFPL PM KML+ S + GCS+E+L+I +M+ +QN+F P ++++
Sbjct: 968 DDEGLLTR-LGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQA 1026
Query: 530 HAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVREQLKKLL 589
A + KF EGDHLT+L +Y ++ + + WC E+F+ + L RA +R+Q+ ++
Sbjct: 1027 LADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIM 1086
Query: 590 VKFQVPRKSSEGDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASVLYAEKP 649
+ ++ S V + I SGFF NAA+ YRT+ D ++IHP+S L+ +
Sbjct: 1087 DRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALF-NRQ 1145
Query: 650 PRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQ--QGTHLSLKAKRAKVQ 701
P WV+Y+E++ T+K YMR+VT I+ WL+E AP F++ T LS + K+ +++
Sbjct: 1146 PEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRLE 1199
>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
Length = 1041
Score = 593 bits (1529), Expect = e-169
Identities = 310/644 (48%), Positives = 440/644 (68%), Gaps = 20/644 (3%)
Query: 46 SIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGV 105
SI+ R+ LPVF R +L I N+Q ++I GETG GK+TQIPQYL E G+T +G +
Sbjct: 391 SIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIAC 450
Query: 106 TQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDP 165
TQPRRVAA++VA RVA E G LG+EVGY IRF+DCT + T ++++TDGML+RE + +P
Sbjct: 451 TQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSE-RTVLRYMTDGMLLREFLSEP 509
Query: 166 LLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNET 225
L YSV+M+DEAHERTL+TDI GL+K + + R +L+++VASAT+D +F FF
Sbjct: 510 DLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFF----- 564
Query: 226 SDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQE 285
D + + GR FPVDIFY ++P DY+++ V +V++IH T+ GD+L FLTGQE
Sbjct: 565 -----DDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQE 619
Query: 286 EVETVVSMLIEQARALARTGMK-RHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNV 344
E+E ML + R R G K R L VLP+YA LPS Q ++F+ RKV+VATN+
Sbjct: 620 EIEAACEMLQDPCR---RLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNI 676
Query: 345 AETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYR 404
AETS TI GI+YV+D GF K ++YNPRT +E L V P S+ASANQRAGR GR +GKC+R
Sbjct: 677 AETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFR 736
Query: 405 LYTEEAFD-KLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELL 463
LYT A+ +L ++TVPE+QR++L V+L LK+LGI +++ F F+ PPP ++++ LE L
Sbjct: 737 LYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQL 796
Query: 464 YALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQN-IFV 522
YALG L+ LT G ++AE P++PM +KM+L S + CS+EIL++AAM+ + N IF
Sbjct: 797 YALGALNHLGELTTS-GRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFY 855
Query: 523 VPPNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVR 582
P ++ HA F + GDHL +LN+Y + + S+WC E+F+ ++ + RA VR
Sbjct: 856 RPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCCENFVQFRSMRRARDVR 915
Query: 583 EQLKKLLVKFQVPRKSSEGDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPAS 642
EQL+ LL + +V S +GD V + I +G+F + AR +G YRT++ + IHP S
Sbjct: 916 EQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSG-YRTVKQQQTVFIHPNS 974
Query: 643 VLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQ 686
L+ E+ PRW++Y+E++ T+K +MR V IES+WLLE+APH+Y+
Sbjct: 975 SLF-EQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYK 1017
>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
sapiens]
Length = 795
Score = 566 bits (1459), Expect = e-161
Identities = 297/665 (44%), Positives = 443/665 (66%), Gaps = 30/665 (4%)
Query: 47 IEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEG--RVVG 104
I ++R +LPV++ ++ ++ +Q+ V+VGETG GK+TQIPQ+ E + G R V
Sbjct: 130 ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVA 189
Query: 105 VTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVD 164
TQPRRVAA++VA RVA+E +LG EVGY IRF+DC+ T +K++TDGML+RE M D
Sbjct: 190 CTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSA-KTILKYMTDGMLLREAMND 248
Query: 165 PLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNE 224
PLL +Y VI+LDEAHERTL TDI +G+LK++ ++R DL++IV SATLDA KF+ +F
Sbjct: 249 PLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYF---- 304
Query: 225 TSDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGD-GDVLAFLTG 283
D C +LT+ GRT PV+IFY P DY+++ + TV++IH E + GD+L FLTG
Sbjct: 305 ------DNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTG 358
Query: 284 QEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFE------RVSRSVRK 337
QEE++ + + L ++++P+Y+ LP +Q ++FE + RK
Sbjct: 359 QEEIDEACKRIKREVDDLGPE--VGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRK 416
Query: 338 VIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRS 397
V+V+TN+AETS+TI G+V+VID GF K + YNPR +E L+V +S+ASA QRAGR GR+
Sbjct: 417 VVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRT 476
Query: 398 RSGKCYRLYTEEAFD-KLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSM 456
R GKC+RLYTE+A+ ++ +T PE+ RSNL V+LQLK LGID+++ F FM PP +++
Sbjct: 477 RPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETL 536
Query: 457 VQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQ 516
++ALELL L L+ D LTE LG +AEFPL+P AKM++ S ++ CS E+LSI AM+
Sbjct: 537 MRALELLNYLAALNDDGDLTE-LGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLS 595
Query: 517 IQNIFVVPPNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLV 576
+ FV P K A +FA +GDHLT+LN+Y AF ++++ +WC ++F+NY+ L+
Sbjct: 596 VPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLM 655
Query: 577 RAATVREQLKKLLVKFQVPRKSSEGDPD----LVLRCIVSGFFANAARFHSTGAYRTIRD 632
A VR+QL +++ +F +PR+S++ + + +V+G+F A TG Y T++D
Sbjct: 656 SADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKD 715
Query: 633 DHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLS 692
+ + +HP++VL + P WV+YNE + T+K Y+R T I+ WL+++AP +Y
Sbjct: 716 NQVVQLHPSTVL--DHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQ 773
Query: 693 LKAKR 697
+AKR
Sbjct: 774 CEAKR 778
>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
Length = 1227
Score = 558 bits (1438), Expect = e-159
Identities = 291/659 (44%), Positives = 430/659 (65%), Gaps = 21/659 (3%)
Query: 46 SIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGV 105
SI +QRQ LP+F ++ +L +I + V++VGETG GK+TQ+ QYL E G+T G ++G
Sbjct: 524 SILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYG-MIGC 582
Query: 106 TQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDP 165
TQPRRVAA++VA RV+EE G LG EVGY IRF+DCT + T IK++TDG+L+RE + +
Sbjct: 583 TQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSE-NTLIKYMTDGILLRESLREA 641
Query: 166 LLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNET 225
L YS I++DEAHER+L TD+ GLL+++ +R DL+LIV SAT+DA+KF FF
Sbjct: 642 DLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGN--- 698
Query: 226 SDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQE 285
I + GRTFPVDI + ++P DY+++ V+ +++H + GD+L F+ GQE
Sbjct: 699 -------VPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHLSGAPGDILIFMPGQE 751
Query: 286 EVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVA 345
++E ++E L L VLP+Y+ LPS Q K+F++ VRK IVATN+A
Sbjct: 752 DIEVTSDQIVEHLEELENAPA---LAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIA 808
Query: 346 ETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRL 405
ETS+T+ GI++VID G+ KL+ +NPR ++ L + P+SQA+ANQR+GR GR+ G+C+RL
Sbjct: 809 ETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRL 868
Query: 406 YTEEAF-DKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLY 464
YT+ A+ ++L +TVPE+QR+NLA V+L LK+LG+ ++L+FHFM PPP +M+ ++ L+
Sbjct: 869 YTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLW 928
Query: 465 ALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVP 524
LG LD LT G + EFPL+P +KML+ S + GCS EIL I +M+ + IF P
Sbjct: 929 ILGALDNTGGLTST-GRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRP 987
Query: 525 PNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVREQ 584
++ + ++ KFAV E DHLT LN+Y + +N + WC +HF++ K + + VR Q
Sbjct: 988 KGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQ 1047
Query: 585 LKKLLVKFQVPRKSSEGDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASVL 644
LK ++V+ ++ S D D+V +CI + +F AA+ G Y IR H+HP S L
Sbjct: 1048 LKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGIGEYVNIRTGMPCHLHPTSSL 1107
Query: 645 YA-EKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFY---QQGTHLSLKAKRAK 699
+ P +++Y+E++ T+K YM+ VTA++ WL EL P FY Q G +RAK
Sbjct: 1108 FGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVKQAGKSRQENRRRAK 1166
>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo
sapiens]
Length = 707
Score = 541 bits (1393), Expect = e-153
Identities = 293/656 (44%), Positives = 417/656 (63%), Gaps = 24/656 (3%)
Query: 40 NPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAE 99
+PY ++E QR+ LP+F+ R +L + N V++GETG GK+TQIPQYL E G + +
Sbjct: 61 SPYPE-AVELQRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQ 119
Query: 100 GRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVR 159
G ++ VTQPRRVAA+++A RV++E+ LG VGY +RFDD T + TRIKFLTDGML+R
Sbjct: 120 G-IIAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFDDVTSE-DTRIKFLTDGMLLR 177
Query: 160 EMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDL-----RLIVASATLDAD 214
E + D LL KYS ++LDEAHERT++TD+ G++K QK+R +L ++IV SAT+D D
Sbjct: 178 EAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMDVD 237
Query: 215 KFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQ-TEG 273
F +FN +L +EGR P+ +FY + P DY+ + + +V +IHQ
Sbjct: 238 LFSQYFNG----------APVLYLEGRQHPIQVFYTKQPQNDYLHAALVSVFQIHQEAPS 287
Query: 274 DGDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSR 333
D+L FLTGQEE+E + + A+ L G L VLP+YA LP +Q++VF+ +
Sbjct: 288 SQDILVFLTGQEEIEAMSKTCRDIAKHLP-DGCPAML-VLPLYASLPYAQQLRVFQGAPK 345
Query: 334 SVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGR 393
RKVI++TN+AETSITI+GI YV+D G VK + YNP + +E L V VS+ A QR GR
Sbjct: 346 GYRKVIISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGR 405
Query: 394 GGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPA 453
GR SG CYRLYTE+ F+K + TVPE+QR NLA V+LQL A+ + NVL F FMS P
Sbjct: 406 AGREDSGICYRLYTEDEFEKFDKMTVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSKPSP 465
Query: 454 QSMVQALELLYALGGLD-KDCRLT-EPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSI 511
+ A+ L LG L+ KD +LT P+G ++A FPL P FAK +L S F C++EIL+I
Sbjct: 466 DHIQAAIAQLDLLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTI 525
Query: 512 AAMMQIQNIFVVPPNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLN 571
+++ + ++ PP+++ V +KF EGDH+T+LNIY F + WC+E+F+N
Sbjct: 526 VSLLSVDSVLHNPPSRREEVQGVRKKFISSEGDHMTLLNIYRTFKNLGGNKDWCKENFVN 585
Query: 572 YKGLVRAATVREQLKKLLVKFQVPRKSSEGDPDLVLRCIVSGFFANAARFHSTGAYRTIR 631
K + A VR QL+ + +K +P SS GD + V RC+ F + A G Y T
Sbjct: 586 SKNMTLVAEVRAQLRDICLKMSMPIASSRGDVESVRRCLAHSLFMSTAELQPDGTYATTD 645
Query: 632 DDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQ 687
+ IHP+SVL+ K P V+Y E++ T+K YMRD+ I++ WL E AP ++++
Sbjct: 646 THQPVAIHPSSVLFHCK-PACVVYTELLYTNKCYMRDLCVIDAQWLYEAAPEYFRR 700
>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo
sapiens]
Length = 779
Score = 439 bits (1128), Expect = e-123
Identities = 256/709 (36%), Positives = 414/709 (58%), Gaps = 58/709 (8%)
Query: 24 EERQSLAENSGTTVVYNPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGK 83
EE+ ++ GTT + P+ K R I+ + + +++ G TG GK
Sbjct: 38 EEKGCTSQEGGTTPTF---------------PIQKQRKKIIQAVRDNSFLIVTGNTGSGK 82
Query: 84 STQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTD 143
+TQ+P+YL EAG++ G ++GVTQPR+VAA++VA RVAEE LG +VGY +RFDDC+
Sbjct: 83 TTQLPKYLYEAGFSQHG-MIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSS 141
Query: 144 QLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGD-- 201
+ T IK++TDG L++ ++ DP LTK+SVI+LDEAHERTL TDI GLLKK+ +++
Sbjct: 142 K-ETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNR 200
Query: 202 ---LRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPD-- 256
L+++V SAT++ K FF C I + GR +PV + P
Sbjct: 201 KEHLKVVVMSATMELAKLSAFFGN----------CPIFDIPGRLYPVREKFCNLIGPRDR 250
Query: 257 ----YIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARAL-----ARTGMK 307
YI++ VE + IH E GD+L FLTGQ E+E +L + A ++ +
Sbjct: 251 ENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTL 310
Query: 308 RHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRA 367
L +LP Y + + +Q ++F +RK +++TN++ TS+TI GI YV+D GFVK
Sbjct: 311 DGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLN 370
Query: 368 YNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDK-LPQSTVPEMQRSN 426
+NPR ++ L VVP+S++ A QR+GR GR+ SGKC+R+Y+++ +++ +P +PE++R++
Sbjct: 371 HNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTS 430
Query: 427 LAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEF 486
L V+L LK L I +V+RF ++ PP + +++AL+ LY +D+ +T LG+ + EF
Sbjct: 431 LTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTR-LGLSMVEF 489
Query: 487 PLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVP--PNQKSHAIRVHRKFAVEEG- 543
PL P ++++ + C +L IAAM+ ++N+F+ P P + A + HR+ A + G
Sbjct: 490 PLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGG 549
Query: 544 --DHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQ----VPRK 597
D T+ I+E + WCQ+H+++++ L A V QL++L+ K + P++
Sbjct: 550 FNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPKE 609
Query: 598 SSEGDPDLVL-RCIVSGFFANAARFHSTGAYRTIRD-DHELHIHPASVLYAEKPP-RWVI 654
+ EG VL RC+ +G+F N AR + T+ +HIHP+S L+ ++ W+I
Sbjct: 610 TFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTVDGRGSPVHIHPSSALHEQETKLEWII 669
Query: 655 YNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTH-LSLKAKRAKVQD 702
++EV+ T+K Y R V I W+ +L P ++ H LS A+R +D
Sbjct: 670 FHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVRED 718
>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
sapiens]
Length = 1143
Score = 332 bits (851), Expect = 7e-91
Identities = 204/594 (34%), Positives = 324/594 (54%), Gaps = 42/594 (7%)
Query: 14 GTEGPGVSISEERQSLAE--NSGTTVVYNPYAALSIEQQRQKLPVFKLRNHILYLIENYQ 71
G P ++E R++L + G + A L +++R LP+ + N IL ++ +Q
Sbjct: 122 GRHLPAERVAEFRRALLHYLDFGQKQAFGRLAKL--QRERAALPIAQYGNRILQTLKEHQ 179
Query: 72 TVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHE 131
VV+ G+TGCGKSTQ+PQYL AG++ V TQPRR+A +++A RV E + G +
Sbjct: 180 VVVVAGDTGCGKSTQVPQYLLAAGFSH----VACTQPRRIACISLAKRVGFESLSQYGSQ 235
Query: 132 VGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGL 191
VGY IRF+ T AT+I FLT G+L+R++ +P L +Y V+++DE HER L+ D +G+
Sbjct: 236 VGYQIRFES-TRSAATKIVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGV 294
Query: 192 LKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYL- 250
L+++ R DL++I+ SAT++ F +F+ ++ V GR FP+ + Y
Sbjct: 295 LQRLLPTRPDLKVILMSATINISLFSSYFSN----------APVVQVPGRLFPITVVYQP 344
Query: 251 QSPVPDYIKS----------TVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARA 300
Q P KS +E++ + E GD+L FL+G E+ V +E A+
Sbjct: 345 QEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVFLSGMAEISAV----LEAAQT 400
Query: 301 LARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDC 360
A + VLP+++ L +Q KVF+ VRK I++TN+AETS+TI GI +V+D
Sbjct: 401 YA--SHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDS 458
Query: 361 GFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVP 420
G VK +Y+P+ ++ L +SQASA QR GR GR+ G C+RLY E +D VP
Sbjct: 459 GKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAPYPVP 518
Query: 421 EMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLG 480
E++R L ++LQ+K++ + + F F+ PPP S+ A+ L G LD LT P+G
Sbjct: 519 EIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPASLETAILYLRDQGALDSSEALT-PIG 577
Query: 481 MRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAV 540
+A+ P++ + KML+ F + +L+IAA + +Q+ F R
Sbjct: 578 SLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSPFTRSAQSSPECAAARRPLES 637
Query: 541 EEGDHLTMLNIYEAFI-----KHNKDSKWCQEHFLNYKGLVRAATVREQLKKLL 589
++GD T+ N++ A++ + KWC+ + L A +R Q K+LL
Sbjct: 638 DQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIEEHRLYEMANLRRQFKELL 691
>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
sapiens]
Length = 743
Score = 314 bits (804), Expect = 2e-85
Identities = 209/671 (31%), Positives = 351/671 (52%), Gaps = 46/671 (6%)
Query: 41 PYAA--LSIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTA 98
PY++ + ++R+ LP++K + + + Q V++ G+ CGKS Q+PQ+ AE +
Sbjct: 47 PYSSRYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSI 106
Query: 99 EGRVVGV--TQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGM 156
+ GV TQ + V +A RVA+E +GHEVGY I F++C T +++ TD M
Sbjct: 107 HYQHGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTN-ETILRYCTDDM 165
Query: 157 LVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKF 216
L REMM +P L Y VI+LD+ HER++ TD+ +GLLK + R +L+LI+ S+ K
Sbjct: 166 LQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKL 225
Query: 217 RDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGD 276
++ ++ V+ + PV++ YL D +S + + +IH + GD
Sbjct: 226 NSYYG----------NVPVIEVKNK-HPVEVVYLSEAQKDSFESILRLIFEIHHSGEKGD 274
Query: 277 VLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRS-- 334
++ FL ++++E V + + + G L V+P+Y E+ +F+ + +
Sbjct: 275 IVVFLACEQDIEKVCETVYQGSNLNPDLG---ELVVVPLYPK----EKCSLFKPLDETEK 327
Query: 335 -----VRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQ 389
R+V++ T+ E I + + +VID G + + YNPR LV+ P+SQ+ A
Sbjct: 328 RCQVYQRRVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEI 387
Query: 390 RAGRGGRSRSGKCYRLYTEEAFDKLPQSTVP-EMQRSNLAPVILQLKALGIDNVLRFHFM 448
R G S SGK + LYTEE K P EMQ +NL ++L +K + I + FM
Sbjct: 388 RKQILGSSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFM 447
Query: 449 SPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEI 508
+ P +S++QALE L L LD D L+E G+ ++EFPL+P +K +L S F C E+
Sbjct: 448 NRPAPESLMQALEDLDYLAALDNDGNLSE-FGIIMSEFPLDPQLSKSILASCEFDCVDEV 506
Query: 509 LSIAAMMQIQNIFV-VPPNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDS----- 562
L+IAAM+ N F VP + A+ + F EGDH T+++IY+A+ +S
Sbjct: 507 LTIAAMVTAPNCFSHVPHGAEEAALTCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYC 566
Query: 563 --KWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPRK----SSEGDPDLVLRCIVSGFFA 616
KWC+++FLN L A +R +L +++ + ++P S+ + + + ++SG+F
Sbjct: 567 VEKWCRDYFLNCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFM 626
Query: 617 NAAR-FHSTGAYRTIRDDHELHIHPAS-VLYAEKPPRWVIYNEVIQTSKYYMRDVTAIES 674
AR +G Y + +HP S +K P WV++++ + Y+R + I
Sbjct: 627 QIARDVDGSGNYLMLTHKQVAQLHPLSGYSITKKMPEWVLFHKFSISENNYIRITSEISP 686
Query: 675 AWLLELAPHFY 685
++L P +Y
Sbjct: 687 ELFMQLVPQYY 697
>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
polypeptide 40 [Homo sapiens]
Length = 452
Score = 305 bits (782), Expect = 7e-83
Identities = 171/439 (38%), Positives = 268/439 (61%), Gaps = 44/439 (10%)
Query: 24 EERQSLAENSGTTVVYNPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGK 83
EE+ ++ GTT + P+ K R I+ + + +++ G TG GK
Sbjct: 38 EEKGCTSQEGGTTPTF---------------PIQKQRKKIIQAVRDNSFLIVTGNTGSGK 82
Query: 84 STQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTD 143
+TQ+P+YL EAG++ G ++GVTQPR+VAA++VA RVAEE LG +VGY +RFDDC+
Sbjct: 83 TTQLPKYLYEAGFSQHG-MIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSS 141
Query: 144 QLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGD-- 201
+ T IK++TDG L++ ++ DP LTK+SVI+LDEAHERTL TDI GLLKK+ +++
Sbjct: 142 K-ETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNR 200
Query: 202 ---LRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPD-- 256
L+++V SAT++ K FF C I + GR +PV + P
Sbjct: 201 KEHLKVVVMSATMELAKLSAFFGN----------CPIFDIPGRLYPVREKFCNLIGPRDR 250
Query: 257 ----YIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARAL-----ARTGMK 307
YI++ V+ + IH E GD+L FLTGQ E+E +L + A ++ + +
Sbjct: 251 ENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTIL 310
Query: 308 RHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRA 367
L +LP Y + + +Q ++F +RK +++TN++ TS+TI GI YV+D GFVK
Sbjct: 311 DGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLN 370
Query: 368 YNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDK-LPQSTVPEMQRSN 426
+NPR ++ L VVP+S++ A QR+GR GR+ SGKC+R+Y+++ +++ +P +PE++R++
Sbjct: 371 HNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTS 430
Query: 427 LAPVILQLKALGIDNVLRF 445
L V+L LK L I +V+R+
Sbjct: 431 LTSVVLTLKCLAIHDVIRY 449
>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
[Homo sapiens]
Length = 1008
Score = 295 bits (756), Expect = 7e-80
Identities = 214/738 (28%), Positives = 359/738 (48%), Gaps = 118/738 (15%)
Query: 40 NPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLA----EAG 95
N + ++ R+KLP + ++ ++ LI+N+Q VI GETGCGK+TQ+ Q++ E G
Sbjct: 193 NDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERG 252
Query: 96 WTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLG--HEVGYCIRFDDCTDQLATRIKFLT 153
+ R+V TQPRR++A++VA RVA ER G + GY IR + I + T
Sbjct: 253 KGSACRIV-CTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCT 311
Query: 154 DGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDA 213
G++++ + DP L+ S I+LDE HER L +D+ + ++K + R DL++I+ SATL+A
Sbjct: 312 TGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNA 371
Query: 214 DKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPV------------------- 254
+KF ++F C ++ + G TFPV + L+ +
Sbjct: 372 EKFSEYFGN----------CPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRG 421
Query: 255 ----------------------PDYIK--------STVETVVKIHQT------------- 271
PDY++ STV+ + +
Sbjct: 422 FMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRY 481
Query: 272 ----EGDGDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKV 327
E DG +L FL G + + T+ +L+ Q + + ++P+++ +P+ Q +V
Sbjct: 482 IVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFL-----IIPLHSLMPTVNQTQV 536
Query: 328 FERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASA 387
F+R VRK+++ATN+AETSITI +VYVID G +K ++ + I + VS+A+A
Sbjct: 537 FKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANA 596
Query: 388 NQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRF-- 445
QR GR GR + G CY LY L +PE+ R+ L + LQ+K L + + F
Sbjct: 597 KQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLS 656
Query: 446 HFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCS 505
M PP ++++ ++ L L LDK LT PLG+ +A P+ P KM+L F C
Sbjct: 657 RLMDPPSNEAVLLSIRHLMELNALDKQEELT-PLGVHLARLPVEPHIGKMILFGALFCCL 715
Query: 506 QEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAVE-EGDHLTMLNIYEAF-------IK 557
+L+IAA + ++ FV+P ++ A ++ A + DHLT++N +E + +
Sbjct: 716 DPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFR 775
Query: 558 HNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSEGDPD---------LVLR 608
+ KD +C E+FL+ L ++ Q + L+ + DP+ ++
Sbjct: 776 YEKD--YCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKA 833
Query: 609 CIVSGFFANAARFH-STGAYRTI-----RDDHELHIHPASVLYAEKP--PRWVIYNEVIQ 660
I +G + A+ + G R + + D + +HP SV + W+IY+ ++
Sbjct: 834 VICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMR 893
Query: 661 TSKYYMRDVTAIESAWLL 678
TS Y+ D T + LL
Sbjct: 894 TSSIYLYDCTEVSPYCLL 911
>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
[Homo sapiens]
Length = 994
Score = 285 bits (729), Expect = 1e-76
Identities = 213/738 (28%), Positives = 349/738 (47%), Gaps = 132/738 (17%)
Query: 40 NPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLA----EAG 95
N + ++ R+KLP + ++ ++ LI+N+Q VI GETGCGK+TQ+ Q++ E G
Sbjct: 193 NDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERG 252
Query: 96 WTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLG--HEVGYCIRFDDCTDQLATRIKFLT 153
+ R+V TQPRR++A++VA RVA ER G + GY IR + I + T
Sbjct: 253 KGSACRIV-CTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCT 311
Query: 154 DGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDA 213
G++++ + DP L+ S I+LDE HER L +D+ + ++K + R DL++I+ SATL+A
Sbjct: 312 TGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNA 371
Query: 214 DKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPV------------------- 254
+KF ++F C ++ + G TFPV + L+ +
Sbjct: 372 EKFSEYFGN----------CPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRG 421
Query: 255 ----------------------PDYIK--------STVETVVKIHQT------------- 271
PDY++ STV+ + +
Sbjct: 422 FMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRY 481
Query: 272 ----EGDGDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKV 327
E DG +L FL G + + T+ +L+ Q S Q +V
Sbjct: 482 IVLEEEDGAILVFLPGWDNISTLHDLLMSQVM-------------------FKSVNQTQV 522
Query: 328 FERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASA 387
F+R VRK+++ATN+AETSITI +VYVID G +K ++ + I + VS+A+A
Sbjct: 523 FKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANA 582
Query: 388 NQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRF-- 445
QR GR GR + G CY LY L +PE+ R+ L + LQ+K L + + F
Sbjct: 583 KQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLS 642
Query: 446 HFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCS 505
M PP ++++ ++ L L LDK LT PLG+ +A P+ P KM+L F C
Sbjct: 643 RLMDPPSNEAVLLSIRHLMELNALDKQEELT-PLGVHLARLPVEPHIGKMILFGALFCCL 701
Query: 506 QEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAVE-EGDHLTMLNIYEAF-------IK 557
+L+IAA + ++ FV+P ++ A ++ A + DHLT++N +E + +
Sbjct: 702 DPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFR 761
Query: 558 HNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSEGDPD---------LVLR 608
+ KD +C E+FL+ L ++ Q + L+ + DP+ ++
Sbjct: 762 YEKD--YCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKA 819
Query: 609 CIVSGFFANAARFH-STGAYRTI-----RDDHELHIHPASVLYAEKP--PRWVIYNEVIQ 660
I +G + A+ + G R + + D + +HP SV + W+IY+ ++
Sbjct: 820 VICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMR 879
Query: 661 TSKYYMRDVTAIESAWLL 678
TS Y+ D T + LL
Sbjct: 880 TSSIYLYDCTEVSPYCLL 897
>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
sapiens]
Length = 717
Score = 285 bits (729), Expect = 1e-76
Identities = 216/654 (33%), Positives = 334/654 (51%), Gaps = 35/654 (5%)
Query: 49 QQRQKLPVFKLRNHILYLIENYQT--VVIVGETGCGKSTQIPQYLAE---AGWTAEGRVV 103
+QRQ LP++ R L +E+ T V++ GE G GKSTQIPQ+ AE A +G+V
Sbjct: 40 KQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQKGQVT 99
Query: 104 GVTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMV 163
VTQP +AA ++A RVA+E LGHEVGY I +DCT T ++F D +L++E+
Sbjct: 100 -VTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGP-NTLLRFCWDRLLLQEVAS 157
Query: 164 DPLLTKYSVIMLDEAHERTLYTDIAIGLLK--KIQKKRGDLRLIVASATLDADKFRDFFN 221
+ V++LDEA ER++ +D GLL+ +++K GDLR++V + K R F+
Sbjct: 158 TRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEPKLRAFWG 217
Query: 222 QNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFL 281
V + E P I++ P PD +++ + V+++ + E GDVL FL
Sbjct: 218 N--------PPIVHIPREPGERPSPIYWDTIP-PDRVEAACQAVLELCRKELPGDVLVFL 268
Query: 282 TGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVA 341
+EE+ L + +L G+ RVLP++ Q V+E + RKV+V
Sbjct: 269 PSEEEISLCCESLSREVESLLLQGLPP--RVLPLHPDCGRAVQA-VYEDMD--ARKVVVT 323
Query: 342 TNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGK 401
+A+ S ++ I +VID G YNPR E V+ P+S+ A R R G
Sbjct: 324 HWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGFPPGS 383
Query: 402 CYRLYTEEAFD-KLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQAL 460
C LY + + + P P + NL+ ++L LK I HF+ P ++++QAL
Sbjct: 384 CLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFLDQPAPEALMQAL 443
Query: 461 ELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNI 520
E L L LD D L++ LG+ ++EFPL P AK LL S F C E+L++AAM+
Sbjct: 444 EDLDYLAALDDDGDLSD-LGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAAPG 502
Query: 521 FVVPPNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAAT 580
F PP A + R +GDH +++ +YEAFI+ D WCQ LN+ L +A
Sbjct: 503 FTRPPLSAEEAA-LRRALEHTDGDHSSLIQVYEAFIQSGADEAWCQARGLNWAALCQAHK 561
Query: 581 VREQLKKLLVKFQVPRK----SSEGDPDLVLRCIVSGFFANAAR-FHSTGAYRTIRDDHE 635
+R +L +L+ + ++P SE + + + +VSG+F AR TG Y + H
Sbjct: 562 LRGELLELMQRIELPLSLPAFGSEQNRRDLQKALVSGYFLKVARDTDGTGNYLLLTHKHV 621
Query: 636 LHIHP----ASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFY 685
+ S +PP WV+Y+ + + V+ I+ L+ELAP ++
Sbjct: 622 AQLSSYCCYRSRRAPARPPPWVLYHNFTISKDNCLSIVSEIQPQMLVELAPPYF 675
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
Length = 1270
Score = 258 bits (659), Expect = 1e-68
Identities = 217/775 (28%), Positives = 356/775 (45%), Gaps = 98/775 (12%)
Query: 7 PVKFWRPGT-----EGPGVSISEERQSL-AENSGTTVVYNPYAALSIEQQRQKLPVFKLR 60
P W P T EGP + E+ S+ +N + + +I Q+R+ LPV K
Sbjct: 335 PQSNWNPWTSSNIDEGPLAFATPEQISMDLKNELMYQLEQDHDLQAILQERELLPVKKFE 394
Query: 61 NHILYLIENYQTVVIVGETGCGKSTQIPQYLAEA----GWTAEGRVVGVTQPRRVAAVTV 116
+ IL I V+I G TGCGK+TQ+PQ++ + AE +V VTQPRR++AV+V
Sbjct: 395 SEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNIV-VTQPRRISAVSV 453
Query: 117 AGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLD 176
A RVA ERG G GY +RF+ + I F T G+L+R++ + S +++D
Sbjct: 454 AERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAG--IRGISHVIVD 511
Query: 177 EAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPARDTCVIL 236
E HER + TD + +L+ + + ++R+++ SAT+D F ++F C I+
Sbjct: 512 EIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFN----------CPII 561
Query: 237 TVEGRTFPVDIFYLQSPVP--DYIKSTVETVVKIHQTEGDGDVLA---FLTGQE------ 285
V GRT+PV ++L+ + ++ + K +G D A + G E
Sbjct: 562 EVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGPETR 621
Query: 286 -------EVET---VVSMLIEQARALARTG--------------MKRHL----------- 310
E ET ++ L++ L G M++HL
Sbjct: 622 LSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFGSHRY 681
Query: 311 RVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNP 370
++LP+++ +P EQ KVF+ V V KVI++TN+AETSITI+ +VYVID K++ +
Sbjct: 682 QILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTA 741
Query: 371 RTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPV 430
+ V S+ + QR GR GR R G C+ L + F++L PEM R+ L +
Sbjct: 742 HNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEI 801
Query: 431 ILQLKALGIDNVLRF--HFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPL 488
L +K L + + +F + PPP ++++A L L LD + LT PLG +A+ P+
Sbjct: 802 ALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELT-PLGRILAKLPI 860
Query: 489 NPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAVEE-GDHLT 547
P F KM++ F I +IAA F+ N+ +HR FA DH+
Sbjct: 861 EPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFI---NEGKRLGYIHRNFAGNRFSDHVA 917
Query: 548 MLNIYEAFIK-----HNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQVP------- 595
+L++++A+ + ++C+ LN L + QLK++L+ P
Sbjct: 918 LLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQ 977
Query: 596 ---RKSSEGDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASV------LYA 646
+ + D+V+ + G + N +H + IH +SV
Sbjct: 978 VFTNTGPDNNLDVVISLLAFGVYPNVC-YHKEKRKILTTEGRNALIHKSSVNCPFSSQDM 1036
Query: 647 EKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQ 701
+ P + ++ E I+T + +T + LL A Q + L K+Q
Sbjct: 1037 KYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQIVLVDDWIKLQ 1091
>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2
[Homo sapiens]
Length = 1155
Score = 241 bits (614), Expect = 2e-63
Identities = 166/497 (33%), Positives = 262/497 (52%), Gaps = 49/497 (9%)
Query: 49 QQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRV----VG 104
Q+ +LPV R+ IL IE + VVI G+TGCGK+T+IPQ L E + EGR V
Sbjct: 390 QEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLER-YVTEGRGARCNVI 448
Query: 105 VTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVD 164
+TQPRR++AV+VA RV+ E G L VG+ +R + + F T G+L+R++ +
Sbjct: 449 ITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSN 508
Query: 165 PLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNE 224
P L S +++DE HER + TD + LLK +Q+ LRL++ SAT D ++F +F
Sbjct: 509 PSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGG-- 566
Query: 225 TSDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGD---------- 274
C ++ V G +PV YL+ + K + H++E +
Sbjct: 567 --------CPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTD 618
Query: 275 -----------GDVLAFLTGQEEVETVVSMLIEQARALARTGM-KRHLRVLPMYAGLPSF 322
G +L FL G +E++ V Q R GM + +LP+++ +P
Sbjct: 619 LVLHIDARGEPGGILCFLPGWQEIKGV------QQRLQEALGMHESKYLILPVHSNIPMM 672
Query: 323 EQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPV 382
+Q +F++ VRK+++ATN+AETSITI+ IV+V+D G K Y+ +T + CL V V
Sbjct: 673 DQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWV 732
Query: 383 SQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKALGIDNV 442
S+A+ QR GR GR +SG Y L+ +K+ VPE+ R+ L ++LQ K + +
Sbjct: 733 SRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEK 791
Query: 443 LRFHFMS----PPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLE 498
F+S P +++ +A+ LL +G LD+ LT LG R+A +P AK ++
Sbjct: 792 TAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLT-TLGQRLAHISTDPRLAKAIVL 850
Query: 499 SGNFGCSQEILSIAAMM 515
+ F C +L + + +
Sbjct: 851 AAIFRCLHPLLVVVSCL 867
>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1
[Homo sapiens]
Length = 1194
Score = 241 bits (614), Expect = 2e-63
Identities = 166/497 (33%), Positives = 262/497 (52%), Gaps = 49/497 (9%)
Query: 49 QQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRV----VG 104
Q+ +LPV R+ IL IE + VVI G+TGCGK+T+IPQ L E + EGR V
Sbjct: 429 QEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLER-YVTEGRGARCNVI 487
Query: 105 VTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVD 164
+TQPRR++AV+VA RV+ E G L VG+ +R + + F T G+L+R++ +
Sbjct: 488 ITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSN 547
Query: 165 PLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNE 224
P L S +++DE HER + TD + LLK +Q+ LRL++ SAT D ++F +F
Sbjct: 548 PSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGG-- 605
Query: 225 TSDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGD---------- 274
C ++ V G +PV YL+ + K + H++E +
Sbjct: 606 --------CPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTD 657
Query: 275 -----------GDVLAFLTGQEEVETVVSMLIEQARALARTGM-KRHLRVLPMYAGLPSF 322
G +L FL G +E++ V Q R GM + +LP+++ +P
Sbjct: 658 LVLHIDARGEPGGILCFLPGWQEIKGV------QQRLQEALGMHESKYLILPVHSNIPMM 711
Query: 323 EQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPV 382
+Q +F++ VRK+++ATN+AETSITI+ IV+V+D G K Y+ +T + CL V V
Sbjct: 712 DQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWV 771
Query: 383 SQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKALGIDNV 442
S+A+ QR GR GR +SG Y L+ +K+ VPE+ R+ L ++LQ K + +
Sbjct: 772 SRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEK 830
Query: 443 LRFHFMS----PPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLE 498
F+S P +++ +A+ LL +G LD+ LT LG R+A +P AK ++
Sbjct: 831 TAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLT-TLGQRLAHISTDPRLAKAIVL 889
Query: 499 SGNFGCSQEILSIAAMM 515
+ F C +L + + +
Sbjct: 890 AAIFRCLHPLLVVVSCL 906
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 211 bits (536), Expect = 2e-54
Identities = 182/643 (28%), Positives = 305/643 (47%), Gaps = 90/643 (13%)
Query: 15 TEGPGVSISEERQSLAENSGTTVVYNPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVV 74
T GPG R SLA+ S T + + LP+ + + ++ LIE+ V+
Sbjct: 104 TSGPG-----PRPSLAKLSSVTCIPGT------TYKYPDLPISRYKEEVVSLIESNSVVI 152
Query: 75 IVGETGCGKSTQIPQYLAE--AGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEV 132
I G TG GKSTQ+PQY+ + +A +V VTQPR++ A ++A +++ER LG V
Sbjct: 153 IHGATGSGKSTQLPQYILDHYVQRSAYCSIV-VTQPRKIGASSIARWISKERAWTLGGVV 211
Query: 133 GYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLL 192
GY + + + TR+ ++T G+L+++++ L +++ I++DE HERT D + ++
Sbjct: 212 GYQVGLEKIATE-DTRLIYMTTGVLLQKIVSAKSLMEFTHIIIDEVHERTEEMDFLLLVV 270
Query: 193 KKIQKKRGD-LRLIVASATLDADKFRDFFN---QNETSDPARDTCVILTVEGRTFPVDIF 248
+K+ + +++++ SAT+ +F D+F QN+ + PA I VEG+ V+ +
Sbjct: 271 RKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMN-PA----YIFEVEGKPHSVEEY 325
Query: 249 YLQ----------SP----VPDYIKSTVETVVKIHQTEGDGD------------------ 276
YL SP P K E V + Q D D
Sbjct: 326 YLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLIQMFDDLDMKESGNKAWSGAQFVLER 385
Query: 277 --VLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRS 334
VL FL G E+ + +L + L+V P+++ + EQ VF
Sbjct: 386 SSVLVFLPGLGEINYMHELLTSLVH--------KRLQVYPLHSSVALEEQNNVFLSPVPG 437
Query: 335 VRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRG 394
RK+I++TN+AE+S+T+ + YVID + + T + L + S+ S NQR GR
Sbjct: 438 YRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGRA 497
Query: 395 GRSRSGKCYRLYTEEAFD-KLPQSTVPEMQRSNLAPVILQLKAL--GIDNVLRFHFMSPP 451
GR G CYRL ++ +D +P VPEM R L IL++K L G L +SPP
Sbjct: 498 GRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLATALSPP 557
Query: 452 PAQSMVQALELLYALGGL----------DKDCRLTEPLGMRIAEFPLNPMFAKMLLESGN 501
+ + + LL +G L D LT LG +A+ P+N K+++
Sbjct: 558 GLSDIERTILLLKEVGALAVSGQREDENPHDGELTF-LGRVLAQLPVNQQLGKLIVLGHV 616
Query: 502 FGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFA-VEEGDHLTMLNIYEAF----- 555
FGC E L IAA + ++N F +P Q R F+ + D + ++ ++ +
Sbjct: 617 FGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKSDCIALVEAFKTWKACRQ 676
Query: 556 ---IKHNKDS-KWCQEHFLNYKGLVRAATVREQLKKLLVKFQV 594
+++ KD W + +++ K + A + E+LK + +F +
Sbjct: 677 TGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNM 719
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapiens]
Length = 1157
Score = 207 bits (528), Expect = 2e-53
Identities = 148/428 (34%), Positives = 216/428 (50%), Gaps = 53/428 (12%)
Query: 310 LRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYN 369
L VLP+Y+ L +Q +VF+ R +VATNVAETS+TI GI YV+DCG VK R Y+
Sbjct: 588 LHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYD 647
Query: 370 PRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAP 429
T + V VSQASA+QRAGR GR+ G CYRLY+ F Q PE+ R +
Sbjct: 648 RVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVED 707
Query: 430 VILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLD-----------KDCRLTEP 478
+ILQ+KAL ++ V+ F F +PP ++++ A ELL ALG L ++ RL+ P
Sbjct: 708 LILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCP 767
Query: 479 ---LGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVV---PPNQKSHAI 532
LG +A FP+ P +AKML S GC ++I A M ++ +F P
Sbjct: 768 ITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELT 827
Query: 533 RVHRKFA---------------VEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVR 577
R+ K A ++ GD + +L A + ++C+ + L YK ++
Sbjct: 828 RLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKAMME 887
Query: 578 AATVREQLKKLLVKFQVPRKSSEGDPDL---------VLRCIVSGFFAN--AARFHS--- 623
+R QL V P DP + LR IV+ + A R S
Sbjct: 888 IRRLRGQL-TTAVNAVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSEEM 946
Query: 624 -----TGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLL 678
AY+T D + IHP+SVL+ E P +V+Y E+++T+K YM+ V+++E W+
Sbjct: 947 LEDKWRNAYKTPLLDDPVFIHPSSVLFKEL-PEFVVYQEIVETTKMYMKGVSSVEVQWIP 1005
Query: 679 ELAPHFYQ 686
L P + Q
Sbjct: 1006 ALLPSYCQ 1013
Score = 176 bits (447), Expect = 5e-44
Identities = 103/253 (40%), Positives = 156/253 (61%), Gaps = 13/253 (5%)
Query: 47 IEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVT 106
++++R KLP+ I+ + + V++ GETG GK+TQ+PQ+L EAG+++E ++GVT
Sbjct: 245 MQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSIIGVT 304
Query: 107 QPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPL 166
+PRRVAAV ++ RVA+E + V Y IR++ + TRIKF+TDG+L++E+ D L
Sbjct: 305 EPRRVAAVAMSQRVAKEMN-LSQRVVSYQIRYEGNVTE-ETRIKFMTDGVLLKEIQKDFL 362
Query: 167 LTKYSVIMLDEAHERTLYTDIAIGLLKKI----QKKRGDLRLIVASATLDADKFRDFFNQ 222
L +Y V+++DEAHER++YTDI IGLL +I K+ L+L++ SATL + F N
Sbjct: 363 LLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQ--NP 420
Query: 223 NETSDPARDTCVILTVEGRTFPVDI-FYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFL 281
+ P ++ VE R FPV + F ++P+ DY V KIH+ G +L FL
Sbjct: 421 RLFAKPP----PVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFL 476
Query: 282 TGQEEVETVVSML 294
TGQ EV + L
Sbjct: 477 TGQAEVHALCRRL 489
>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
Length = 1386
Score = 180 bits (457), Expect = 4e-45
Identities = 135/475 (28%), Positives = 231/475 (48%), Gaps = 61/475 (12%)
Query: 256 DYIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPM 315
+ I++ +E +V + G +L FL G E++ + L Q+ +L + P+
Sbjct: 829 ELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQL--QSNSLFNNRRSNRCVIHPL 886
Query: 316 YAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIE 375
++ L S EQ VF + V K+I++TN+AETSITI +VYVID G +K + Y+ +E
Sbjct: 887 HSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGME 946
Query: 376 CLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFD-KLPQSTVPEMQRSNLAPVILQL 434
L VSQA+A QR GR GR SG C+ L+T ++ +L + +PE+QR L + L++
Sbjct: 947 SLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRI 1006
Query: 435 KALGIDNVLRF-----HFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLN 489
K L + + + PP S+ + L LG L D RLT PLG +A P++
Sbjct: 1007 KILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLT-PLGYHLASLPVD 1065
Query: 490 PMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAVEEGDHLTML 549
K++L F C L+IAA + ++ FV P ++K A + +FA D+L +L
Sbjct: 1066 VRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALL 1125
Query: 550 NIYEAFIKHNKDS-----KWCQEHFLNYKGLVRAATVREQLKKLLVKF----------QV 594
Y+ + K+ +C+++FL+ + L A+++ Q +LL ++
Sbjct: 1126 QAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREI 1185
Query: 595 PRKSSEGD----------------PDLVLRCIVSGFFANAARFH---------STGAYR- 628
+++ GD P L+ + + + N + STGA R
Sbjct: 1186 EKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRM 1245
Query: 629 ---------TIRDDHELHIHPASVLYAEK--PPRWVIYNEVIQTSKYYMRDVTAI 672
++D +HIHP+SV Y + +++Y+E I+TS+ ++RD + +
Sbjct: 1246 QPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMV 1300
Score = 155 bits (393), Expect = 9e-38
Identities = 90/212 (42%), Positives = 130/212 (61%), Gaps = 14/212 (6%)
Query: 46 SIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVG- 104
SI Q+RQ LP ++ R IL L+ +Q VVI G TGCGK+TQIPQ++ + V
Sbjct: 536 SILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVAN 595
Query: 105 --VTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMM 162
TQPRR++A++VA RVA+ER +G VGY IR + ATR+ + T G+L+R +
Sbjct: 596 IICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSS-ATRLLYCTTGVLLRRLE 654
Query: 163 VDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQ 222
D L S I++DE HERT +D + +LK I +R L++I+ SATL+A+ F D+FN
Sbjct: 655 GDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFN- 713
Query: 223 NETSDPARDTCVILTVEGRTFPVDIFYLQSPV 254
+C ++T+ GRTFPVD F+L+ +
Sbjct: 714 ---------SCPVITIPGRTFPVDQFFLEDAI 736
>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
Length = 1369
Score = 174 bits (442), Expect = 2e-43
Identities = 123/429 (28%), Positives = 201/429 (46%), Gaps = 35/429 (8%)
Query: 274 DGDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSR 333
+G VL FL G ++ + +L R + +V+ +++ L + +Q F
Sbjct: 867 EGAVLIFLPGLAHIQQLYDLLSNDRRFYSE-----RYKVIALHSILSTQDQAAAFTLPPP 921
Query: 334 SVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGR 393
VRK+++ATN+AET ITI +V+VID G K Y+ + + LV VS+ASA QR GR
Sbjct: 922 GVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGR 981
Query: 394 GGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKA--LGIDNVLRFHFMSPP 451
GR R G C+R+YT E F+ +VPE+ R L + L + LG + PP
Sbjct: 982 AGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPP 1041
Query: 452 PAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSI 511
Q + A+ LL +G + + PLG +A P+N KML+ FGC + ++
Sbjct: 1042 QLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATL 1101
Query: 512 AAMMQIQNIFVVPPNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIK------HNKDSKWC 565
AA+M ++ F P +K A A+ + DHLT+ N Y + K + + +C
Sbjct: 1102 AAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYC 1161
Query: 566 QEHFLNYKGLVRAATVREQLKKLL----VKFQVPRKSSEG----------DPDLVLRCIV 611
+ +FLN L+ V+++L KL+ S EG + L+ +V
Sbjct: 1162 RRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLV 1221
Query: 612 SGFFANAARFHSTGAYRTIRD--------DHELHIHPASVLYAEKPPRWVIYNEVIQTSK 663
+G + N + T + + +HP+SV + W++Y E I+ ++
Sbjct: 1222 AGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYAR 1281
Query: 664 YYMRDVTAI 672
Y+R+ T I
Sbjct: 1282 VYLRETTLI 1290
Score = 149 bits (377), Expect = 7e-36
Identities = 83/217 (38%), Positives = 135/217 (62%), Gaps = 20/217 (9%)
Query: 49 QQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEA----GWTAEGRVVG 104
++RQ+LPVFK R+ I+ ++ ++ VV+ GETG GKSTQ+P +L E W A +
Sbjct: 567 KERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIV 626
Query: 105 VTQPRRVAAVTVAGRVAEERGAVLGHE-----VGYCIRFDDCTDQLATRIKFLTDGMLVR 159
TQPRR++AV++A RV +E G G GY IR + + +TR+ + T G+L+R
Sbjct: 627 CTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACE-STRLLYCTTGVLLR 685
Query: 160 EMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDF 219
++ D LL+ S +++DE HER++ +D + +LK+I +KR DL LI+ SAT+D++KF +
Sbjct: 686 KLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTY 745
Query: 220 FNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPD 256
F C IL + GR++PV++F+L+ + +
Sbjct: 746 FTH----------CPILRISGRSYPVEVFHLEDIIEE 772
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 159 bits (402), Expect = 8e-39
Identities = 123/426 (28%), Positives = 206/426 (48%), Gaps = 40/426 (9%)
Query: 275 GDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRS 334
G VL FL G +E+ + ++ + A +V +++ + + +Q KV +
Sbjct: 623 GAVLIFLPGYDEIVGLRDRILFDDKRFADN--THRYQVFMLHSNMQTSDQKKVLKNPPAG 680
Query: 335 VRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRG 394
VRK+I++TN+AETSIT++ +V+VID G VK ++++ + L +V +S+ASA QR GR
Sbjct: 681 VRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRA 740
Query: 395 GRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFM----SP 450
GR R G C+RL++ F + + PE+ R L + L K L N F+ P
Sbjct: 741 GRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEP 800
Query: 451 PPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILS 510
PPA + A+++L + +D LTE LG +A+ P+ P KM+L + C IL+
Sbjct: 801 PPALIVRNAVQMLKTIDAMDTWEDLTE-LGYHLADLPVEPHLGKMVLCAVVLKCLDPILT 859
Query: 511 IAAMMQIQNIFVVP--PNQKSHAIRVHRKF-AVEEGDHLTMLNIYEAFIKHNKDS---KW 564
IA + ++ FV+P +QK A+ ++F A DH+ +L ++A+ K D +
Sbjct: 860 IACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAF 919
Query: 565 CQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSEGDP----------DLVLRCIVSGF 614
C+++FL+ + +R QL L R GD +V +V+G
Sbjct: 920 CEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGM 979
Query: 615 FANAARFHSTGAYRTIRDDHELHIHPASVL----YAEKPPR-------------WVIYNE 657
+ N T + ++ HPASVL Y + PP W+IY+E
Sbjct: 980 YPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPPANGQAAAIKALPTDWLIYDE 1039
Query: 658 VIQTSK 663
+ + +
Sbjct: 1040 MTRAHR 1045
Score = 122 bits (306), Expect = 1e-27
Identities = 74/203 (36%), Positives = 119/203 (58%), Gaps = 13/203 (6%)
Query: 51 RQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGW-TAEGRVVGVTQPR 109
RQ LPVF+ + I+ +I+ + V+IVGETG GK+TQIPQ+L + + + TQPR
Sbjct: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPR 249
Query: 110 RVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMV-DPLLT 168
R+AA+ VA RVA ER +G +GY IR + T + F T+G+L+R +M D L+
Sbjct: 250 RLAAIAVAERVAAERRERIGQTIGYQIRLESRVSP-KTLLTFCTNGVLLRTLMAGDSTLS 308
Query: 169 KYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDP 228
+ +++DE HER ++D + L+ + +K L+LI++SA LD + F +F
Sbjct: 309 TVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFG------- 361
Query: 229 ARDTCVILTVEGRTFPVDIFYLQ 251
+C ++ ++GR F V +L+
Sbjct: 362 ---SCPVIYIQGRPFEVKEMFLE 381
>gi|226492499 septin 12 isoform 1 [Homo sapiens]
Length = 312
Score = 33.9 bits (76), Expect = 0.53
Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 11/111 (9%)
Query: 73 VVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEV 132
+++VG++G GKST + W + +GV P+ + ++ V EE+G L V
Sbjct: 52 IMVVGQSGLGKSTMVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLT-HVIEEKGVKLKLTV 110
Query: 133 ------GYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDE 177
G I D+C L I+FL L R + V P++ + + ++E
Sbjct: 111 TDTPGFGDQINNDNCLRPL--DIEFLQ--RLCRTVNVVPVIARADSLTMEE 157
>gi|226492421 septin 12 isoform 2 [Homo sapiens]
Length = 358
Score = 33.5 bits (75), Expect = 0.69
Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 7/97 (7%)
Query: 73 VVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEV 132
+++VG++G GKST + W + +GV P+ + ++ V EE+G L V
Sbjct: 52 IMVVGQSGLGKSTMVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLT-HVIEEKGVKLKLTV 110
Query: 133 ------GYCIRFDDCTDQLATRIKFLTDGMLVREMMV 163
G I D+C D + I + L E+++
Sbjct: 111 TDTPGFGDQINNDNCWDPILGYINEQYEQYLQEEILI 147
>gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens]
Length = 559
Score = 33.1 bits (74), Expect = 0.90
Identities = 22/56 (39%), Positives = 25/56 (44%)
Query: 229 ARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQ 284
A D VIL V+ T LQS D I S + K+ T GDG AFL Q
Sbjct: 261 ALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQ 316
>gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens]
Length = 1009
Score = 33.1 bits (74), Expect = 0.90
Identities = 22/56 (39%), Positives = 25/56 (44%)
Query: 229 ARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQ 284
A D VIL V+ T LQS D I S + K+ T GDG AFL Q
Sbjct: 261 ALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQ 316
>gi|116734710 ATP-binding cassette, sub-family A member 3 [Homo
sapiens]
Length = 1704
Score = 31.6 bits (70), Expect = 2.6
Identities = 25/128 (19%), Positives = 54/128 (42%), Gaps = 15/128 (11%)
Query: 22 ISEERQSLAENSGTTVVYNPYAALSIEQ-QRQKLPVFKLRNHILYLIENYQTVVIVGETG 80
+++ER + S ++++ P + + Q++P+ + + + ++ + ++G G
Sbjct: 1361 VADERTRILAPSPDSLLHTPLIIKELSKVYEQRVPLLAV-DRLSLAVQKGECFGLLGFNG 1419
Query: 81 CGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDD 140
GK+T E T+ VG R++ + G V +GYC +FD
Sbjct: 1420 AGKTTTFKMLTGEESLTSGDAFVG------------GHRISSDVGKVR-QRIGYCPQFDA 1466
Query: 141 CTDQLATR 148
D + R
Sbjct: 1467 LLDHMTGR 1474
>gi|5729980 phosphomevalonate kinase [Homo sapiens]
Length = 192
Score = 31.2 bits (69), Expect = 3.4
Identities = 15/51 (29%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
Query: 563 KWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSEGDPDLVLRCIVSG 613
++ QEH LN++ L+ +T +E +K ++++ ++ + DP R IV G
Sbjct: 50 QYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKR--QADPGFFCRKIVEG 98
>gi|153945836 endothelin converting enzyme 2 isoform E [Homo
sapiens]
Length = 765
Score = 31.2 bits (69), Expect = 3.4
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 27 QSLAENSGTTVVYNPYAA-LSIEQQRQKLPVFKLRNHILYLI 67
+++A+N G YN Y A L + Q+LP L NH L+ +
Sbjct: 662 ENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFV 703
>gi|153945771 endothelin converting enzyme 2 isoform D [Homo
sapiens]
Length = 811
Score = 31.2 bits (69), Expect = 3.4
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 27 QSLAENSGTTVVYNPYAA-LSIEQQRQKLPVFKLRNHILYLI 67
+++A+N G YN Y A L + Q+LP L NH L+ +
Sbjct: 708 ENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFV 749
>gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens]
Length = 736
Score = 31.2 bits (69), Expect = 3.4
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 27 QSLAENSGTTVVYNPYAA-LSIEQQRQKLPVFKLRNHILYLI 67
+++A+N G YN Y A L + Q+LP L NH L+ +
Sbjct: 633 ENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFV 674
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,112,222
Number of Sequences: 37866
Number of extensions: 1048481
Number of successful extensions: 2619
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2426
Number of HSP's gapped (non-prelim): 75
length of query: 703
length of database: 18,247,518
effective HSP length: 109
effective length of query: 594
effective length of database: 14,120,124
effective search space: 8387353656
effective search space used: 8387353656
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.