BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|20452470 neuropilin- and tolloid-like protein 1 isoform 1 precursor [Homo sapiens] (156 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|20452470 neuropilin- and tolloid-like protein 1 isoform 1 pre... 332 8e-92 gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2 pre... 331 2e-91 gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3 pre... 314 2e-86 gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Ho... 185 1e-47 gi|22547221 tolloid-like 1 [Homo sapiens] 94 5e-20 gi|6912724 tolloid-like 2 [Homo sapiens] 91 3e-19 gi|126091152 cubilin [Homo sapiens] 91 5e-19 gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 89 1e-18 gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 89 1e-18 gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 89 1e-18 gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 89 1e-18 gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 89 1e-18 gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 89 1e-18 gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 89 2e-18 gi|66864913 neuropilin 1 isoform c [Homo sapiens] 89 2e-18 gi|66912178 neuropilin 1 isoform b [Homo sapiens] 89 2e-18 gi|182508169 neuropilin 1 isoform a [Homo sapiens] 89 2e-18 gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 85 3e-17 gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 85 3e-17 gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens] 78 3e-15 gi|13899255 membrane frizzled-related protein [Homo sapiens] 76 1e-14 gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 74 4e-14 gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 73 1e-13 gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [H... 71 4e-13 gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr... 71 4e-13 gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr... 71 4e-13 gi|72384339 CUB domain containing protein 2 [Homo sapiens] 70 7e-13 gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 69 1e-12 gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 69 1e-12 gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 69 1e-12 >gi|20452470 neuropilin- and tolloid-like protein 1 isoform 1 precursor [Homo sapiens] Length = 156 Score = 332 bits (851), Expect = 8e-92 Identities = 156/156 (100%), Positives = 156/156 (100%) Query: 1 MLAEPFPKVVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSK 60 MLAEPFPKVVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSK Sbjct: 1 MLAEPFPKVVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSK 60 Query: 61 YPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQ 120 YPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQ Sbjct: 61 YPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQ 120 Query: 121 NPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPE 156 NPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPE Sbjct: 121 NPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPE 156 >gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2 precursor [Homo sapiens] Length = 532 Score = 331 bits (848), Expect = 2e-91 Identities = 155/156 (99%), Positives = 156/156 (100%) Query: 1 MLAEPFPKVVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSK 60 MLAEPFPKVVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSK Sbjct: 1 MLAEPFPKVVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSK 60 Query: 61 YPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQ 120 YPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQ Sbjct: 61 YPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQ 120 Query: 121 NPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPE 156 NPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP+ Sbjct: 121 NPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPD 156 Score = 33.1 bits (74), Expect = 0.098 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 66 ECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVI 125 +C + I A PR I L F + Y ++ S ECK + + V DG + +FC V+ Sbjct: 200 DCKWYIRAPPRSKIYLRFLD-YEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVM 258 Query: 126 KSSGRFLWIKFFAD 139 +G + I+ +AD Sbjct: 259 LRTGLGV-IRMWAD 271 >gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3 precursor [Homo sapiens] Length = 533 Score = 314 bits (804), Expect = 2e-86 Identities = 146/148 (98%), Positives = 148/148 (100%) Query: 9 VVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECI 68 +VASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECI Sbjct: 10 IVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECI 69 Query: 69 YIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSS 128 YIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSS Sbjct: 70 YIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSS 129 Query: 129 GRFLWIKFFADGELESMGFSARYNFTPE 156 GRFLWIKFFADGELESMGFSARYNFTP+ Sbjct: 130 GRFLWIKFFADGELESMGFSARYNFTPD 157 Score = 33.1 bits (74), Expect = 0.098 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 66 ECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVI 125 +C + I A PR I L F + Y ++ S ECK + + V DG + +FC V+ Sbjct: 201 DCKWYIRAPPRSKIYLRFLD-YEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVM 259 Query: 126 KSSGRFLWIKFFAD 139 +G + I+ +AD Sbjct: 260 LRTGLGV-IRMWAD 272 >gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Homo sapiens] Length = 525 Score = 185 bits (470), Expect = 1e-47 Identities = 78/120 (65%), Positives = 100/120 (83%) Query: 37 SVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECK 96 + QCG W + + GG F SPNYP YPP++ECIYI+EAAPRQ IEL FDE Y IEPS+EC+ Sbjct: 42 ATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECR 101 Query: 97 FDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPE 156 FDH+EVRDGPFGFSP+I R+CG ++PP+I+S+GRF+WIKF +D ELE +GF A+Y+F P+ Sbjct: 102 FDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPD 161 Score = 36.2 bits (82), Expect = 0.012 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Query: 66 ECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVI 125 +CI+ I+A P+ I L F + Y +E S ECK + + V DG + +FC V+ Sbjct: 206 DCIWTIKATPKAKIYLRFLD-YQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVM 264 Query: 126 KSSG 129 +G Sbjct: 265 LKTG 268 >gi|22547221 tolloid-like 1 [Homo sapiens] Length = 1013 Score = 94.0 bits (232), Expect = 5e-20 Identities = 43/107 (40%), Positives = 66/107 (61%), Gaps = 1/107 (0%) Query: 46 HAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDG 105 H+ G+ TSPN+P KYP +EC + I A P I+L F E + IE EC +DH+EV DG Sbjct: 779 HSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSE-FEIEQHQECAYDHLEVFDG 837 Query: 106 PFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 SPI+GR CG + P + ++G ++++F +D ++ GF A ++ Sbjct: 838 ETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHS 884 Score = 90.9 bits (224), Expect = 4e-19 Identities = 46/112 (41%), Positives = 65/112 (58%), Gaps = 2/112 (1%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + EG I SPNYP Y P +EC++ I + + L F + + IE C +D+ Sbjct: 462 CGGEIRKNEGQI-QSPNYPDDYRPMKECVWKITVSESYHVGLTF-QSFEIERHDNCAYDY 519 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +EVRDG SP+IGRFCG P I+S+ LW+KF +DG + GF+A + Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF 571 Score = 75.5 bits (184), Expect = 2e-14 Identities = 40/112 (35%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + + G + +SP +P+ YP CI+ + P + I L F + S C +D+ Sbjct: 349 CGETLQESNGNL-SSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTM-DLYKSSLCWYDY 406 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 IEVRDG + SP++GRFCG + P V+ S+ +WI+F + GF+A Y Sbjct: 407 IEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVY 458 Score = 69.7 bits (169), Expect = 9e-13 Identities = 33/102 (32%), Positives = 58/102 (56%), Gaps = 1/102 (0%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G T+P +P +YPP++ C++ + A + I + F E + +E + CK+D++E+ G Sbjct: 627 GTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKF-EFFELEGNEVCKYDYVEIWSGLSSE 685 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 S + G+FCG + P VI S + I+F +D + GF A + Sbjct: 686 SKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHF 727 Score = 52.8 bits (125), Expect = 1e-07 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 1/93 (1%) Query: 59 SKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCG 118 + YP +C +++ + +EL F + + +E +C +D++E+ DG + +GRFCG Sbjct: 909 NNYPGQVDCEWLLVSERGSRLELSF-QTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCG 967 Query: 119 QQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 P I S G + I F D + GF RY Sbjct: 968 SGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRY 1000 >gi|6912724 tolloid-like 2 [Homo sapiens] Length = 1015 Score = 91.3 bits (225), Expect = 3e-19 Identities = 40/100 (40%), Positives = 62/100 (62%), Gaps = 1/100 (1%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G SPN+P KYP REC + I + ++L F+E + IE EC +DH+E+ DGP Sbjct: 785 GTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNE-FEIEQHQECAYDHLEMYDGPDSL 843 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSA 149 +PI+GRFCG + P +SG ++++F++D ++ GF A Sbjct: 844 APILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883 Score = 90.1 bits (222), Expect = 7e-19 Identities = 42/104 (40%), Positives = 61/104 (58%), Gaps = 1/104 (0%) Query: 48 EGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPF 107 + G SPNYP Y P +EC++ I + + L F + + IE C +D++EVRDGP Sbjct: 471 DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTF-QAFEIERHDSCAYDYLEVRDGPT 529 Query: 108 GFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 S +IG FCG + P +KSS LW+KF +DG + GF+A + Sbjct: 530 EESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573 Score = 74.3 bits (181), Expect = 4e-14 Identities = 39/114 (34%), Positives = 62/114 (54%), Gaps = 2/114 (1%) Query: 38 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKF 97 V CG + G I TSP +P +YP ++ C++ + A + I L F E + +E + CK+ Sbjct: 618 VACGGFITKLNGTI-TSPGWPKEYPTNKNCVWQVVAPAQYRISLQF-EVFELEGNDVCKY 675 Query: 98 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 D +EVR G + + GRFCG + P VI S + ++F +D + GF A + Sbjct: 676 DFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF 729 Score = 73.2 bits (178), Expect = 9e-14 Identities = 39/119 (32%), Positives = 62/119 (52%), Gaps = 2/119 (1%) Query: 36 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 95 K CG + G F++P +P+ YP C++ I P + I L F + S C Sbjct: 347 KCPACGETLQDTTGN-FSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSM-DLFKSRLC 404 Query: 96 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFT 154 +D++EVRDG + +P++GRFCG + P + S+ LW++F + + GF A Y T Sbjct: 405 WYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEAT 463 Score = 62.0 bits (149), Expect = 2e-10 Identities = 47/159 (29%), Positives = 75/159 (47%), Gaps = 16/159 (10%) Query: 4 EPFPKVVA--SLIILHLSGAT--KKGTEKQTTSETQKSVQCGTWTK----HAEGGIFTSP 55 +P P V + S+ + S A+ +KG + ++E ++ TK HA+ G Sbjct: 855 KPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFG----- 909 Query: 56 NYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGR 115 + YP + C ++I A +EL F + +E +C +D++E DG +P +GR Sbjct: 910 --DNNYPSEARCDWVIVAEDGYGVELTF-RTFEVEEEADCGYDYMEAYDGYDSSAPRLGR 966 Query: 116 FCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFT 154 FCG I S+G L I+F D + GF ARY T Sbjct: 967 FCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTST 1005 >gi|126091152 cubilin [Homo sapiens] Length = 3623 Score = 90.5 bits (223), Expect = 5e-19 Identities = 44/120 (36%), Positives = 72/120 (60%), Gaps = 3/120 (2%) Query: 36 KSVQCG--TWTKHAEG-GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPS 92 KS+ CG + A+ G TSPN+P YPP +CI+I+ A P I+L F++++ IE + Sbjct: 2213 KSLACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVT 2272 Query: 93 WECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 C +++E+RDG +PI+ +FCG P SSG ++++F +D +GF A+Y+ Sbjct: 2273 PNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYS 2332 Score = 81.3 bits (199), Expect = 3e-16 Identities = 42/123 (34%), Positives = 67/123 (54%), Gaps = 3/123 (2%) Query: 33 ETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPS 92 ETQ+ +CG G I SP YP YPP R+C++I+ +P + F S+E Sbjct: 584 ETQQP-ECGGILTGPYGSI-KSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGT-LSLEHH 640 Query: 93 WECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 +C D++E+RDGP P++G+FC + P ++++G F I F +D ++ GF Y Sbjct: 641 DDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYL 700 Query: 153 FTP 155 +P Sbjct: 701 TSP 703 Score = 79.7 bits (195), Expect = 9e-16 Identities = 41/105 (39%), Positives = 58/105 (55%), Gaps = 1/105 (0%) Query: 48 EGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPF 107 + G+ TSPNYP+ Y C ++EA I L F + + IEP C +D + VR+G Sbjct: 2696 DSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSD-FDIEPHTTCAWDSVTVRNGGS 2754 Query: 108 GFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 SPIIG++CG NP I+S L + F +D L+ GF A +N Sbjct: 2755 PESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWN 2799 Score = 77.0 bits (188), Expect = 6e-15 Identities = 44/122 (36%), Positives = 65/122 (53%), Gaps = 4/122 (3%) Query: 31 TSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIE 90 T+ T CG AEG IF SP YP YPP+ EC++ I ++P ++L F + +E Sbjct: 1729 TTVTASVSACGGTFYMAEG-IFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSF-ISFQLE 1786 Query: 91 PSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKS-SGRFLWIKFFADGELESMGFSA 149 S +C D +E+R+G ++GR+CG P S G LW++F +DG GF A Sbjct: 1787 DSQDCSRDFVEIREGN-ATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQA 1845 Query: 150 RY 151 + Sbjct: 1846 TF 1847 Score = 75.1 bits (183), Expect = 2e-14 Identities = 41/103 (39%), Positives = 55/103 (53%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G FTSPN+P+ YP + ECIY I Q I ++F E D +E+RDG + Sbjct: 1057 GTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEK 1116 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 SP++G F G PP I S LW+KF +D GFSA ++ Sbjct: 1117 SPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWD 1159 Score = 73.9 bits (180), Expect = 5e-14 Identities = 38/107 (35%), Positives = 57/107 (53%), Gaps = 1/107 (0%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G F SPNYP Y EC + ++++ EL F + + +E C D++ V DGP Sbjct: 1174 GTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKD-FHLEHHPNCTLDYLAVYDGPSSN 1232 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPE 156 S ++ + CG + PP+I+SSG ++IK D + GF A Y T E Sbjct: 1233 SHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYRQTCE 1279 Score = 73.9 bits (180), Expect = 5e-14 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 4/105 (3%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G F+SP +P++YPP++ECI+ I P I+L + + +E C FD +E+ GP Sbjct: 1400 GSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHD-FDVEYHSRCNFDVLEIYGGPDFH 1458 Query: 110 SPIIGRFCGQ---QNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 SP I + C Q +NP + S+G L I+F D + GF+A + Sbjct: 1459 SPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASW 1503 Score = 71.6 bits (174), Expect = 2e-13 Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%) Query: 50 GIFTSPNYP-SKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFG 108 GI TSP Y + YP D C+Y I + + IEL F + + + PS C D++ + DG Sbjct: 3046 GIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSD-FDVVPSTSCSHDYLAIYDGANT 3104 Query: 109 FSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFT 154 P++G+FCG + PP +KSS + + F D + G+ + T Sbjct: 3105 SDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQT 3150 Score = 67.0 bits (162), Expect = 6e-12 Identities = 40/150 (26%), Positives = 69/150 (46%), Gaps = 5/150 (3%) Query: 6 FPKVVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDR 65 F +++ +++ SG + + S T + C H G SP +P Y D+ Sbjct: 3364 FYSSMSTAMVIFKSGVVNRNSRM---SFTYQIADCNR-DYHKAFGNLRSPGWPDNYDNDK 3419 Query: 66 ECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVI 125 +C + A I L+F IE S EC+ D +EVR+G SP++G++CG P + Sbjct: 3420 DCTVTLTAPQNHTISLFF-HSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPV 3478 Query: 126 KSSGRFLWIKFFADGELESMGFSARYNFTP 155 S L+++F +D G+ + +P Sbjct: 3479 FSQNNELYLRFKSDSVTSDRGYEIIWTSSP 3508 Score = 62.8 bits (151), Expect = 1e-10 Identities = 39/116 (33%), Positives = 56/116 (48%), Gaps = 4/116 (3%) Query: 36 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 95 + + CG + G I SP +P+ YP C + I P I L F E + +E + C Sbjct: 928 EDLACGEILTESTGTI-QSPGHPNVYPHGINCTWHILVQPNHLIHLMF-ETFHLEFHYNC 985 Query: 96 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 D++EV D S +GR+CG+ PP + SSG L + F D +L GF Y Sbjct: 986 TNDYLEVYDTDSETS--LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINY 1039 Score = 62.4 bits (150), Expect = 2e-10 Identities = 43/147 (29%), Positives = 68/147 (46%), Gaps = 6/147 (4%) Query: 2 LAEPFPKVVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKY 61 LA P SL + SG +++ + Q CG + +SP +P+ Y Sbjct: 1586 LANPIVSSGNSLFLRFQSGPSRQNRGFRA----QFRQACGGHILTSSFDTVSSPRFPANY 1641 Query: 62 PPDRECIYIIEAAPR-QCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQ 120 P ++ C +II+A P I L F + +E S C D +E+ DG +P+ GR+CG Sbjct: 1642 PNNQNCSWIIQAQPPLNHITLSFTH-FELERSTTCARDFVEILDGGHEDAPLRGRYCGTD 1700 Query: 121 NPPVIKSSGRFLWIKFFADGELESMGF 147 P I S L ++F +D + + GF Sbjct: 1701 MPHPITSFSSALTLRFVSDSSISAGGF 1727 Score = 60.5 bits (145), Expect = 6e-10 Identities = 32/114 (28%), Positives = 60/114 (52%), Gaps = 3/114 (2%) Query: 40 CGTWTKHAEGGIFT-SPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFD 98 CG + + + +F SP +P Y +C ++I+A P +EL IE C +D Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQA-PDSTVELNI-LSLDIESHRTCAYD 2035 Query: 99 HIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 + +RDG + + CG++ P I+S+G +++I+F +D + GF+A ++ Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFH 2089 Score = 58.5 bits (140), Expect = 2e-09 Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 11/121 (9%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC---K 96 CG + HA+ GI TSP YP YP + C + + I ++F++ + I P+ + + Sbjct: 2092 CGGYL-HADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQI-PNGDSSCNQ 2149 Query: 97 FDHIEVRDGPFGFSPII------GRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSAR 150 D++ +R+GP SP + G FCG + +S ++++F +D E GF + Sbjct: 2150 GDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIK 2209 Query: 151 Y 151 Y Sbjct: 2210 Y 2210 Score = 57.8 bits (138), Expect = 4e-09 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 1/103 (0%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G+ SP +P+ YP +R C + I Q I L F + I S C+ D++E+ Sbjct: 825 GVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTV-FEIGSSAHCETDYVEIGSSSILG 883 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 SP ++CG P I S FL++ F E+ GF A+++ Sbjct: 884 SPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFS 926 Score = 57.4 bits (137), Expect = 5e-09 Identities = 39/104 (37%), Positives = 53/104 (50%), Gaps = 4/104 (3%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDE-KYSIEPSWECKFDHIEVRDGPFG 108 G FTSPNYP+ P R C + I A + I L F+ + + PS C +H+ V +G Sbjct: 2461 GTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPS--CNNEHVIVFNGIRS 2518 Query: 109 FSPIIGRFCGQQN-PPVIKSSGRFLWIKFFADGELESMGFSARY 151 SP + + C N IKSSG + + FF DG GF+A Y Sbjct: 2519 NSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASY 2562 Score = 57.4 bits (137), Expect = 5e-09 Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 7/135 (5%) Query: 22 TKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSK--YPPDRECIYIIEAAPRQCI 79 T KG + CG + F SP+ S Y + C++II A + I Sbjct: 3139 TAKGWKMSFRQTLGPQQGCGGYLT-GSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVI 3197 Query: 80 ELYFDEKYSIEPS---WECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKF 136 L F+ +++E + C +D++++ DG + + G FCG P SSG FL ++F Sbjct: 3198 HLTFNT-FALEAASTRQRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQF 3256 Query: 137 FADGELESMGFSARY 151 +D LE GF+A Y Sbjct: 3257 ISDLTLEREGFNATY 3271 Score = 55.1 bits (131), Expect = 2e-08 Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 16/150 (10%) Query: 14 IILHLSGATKKG--TEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPS--KYPPDRECIY 69 +I G+ G T T+SE CG + G FTSP Y Y + C + Sbjct: 2545 VIFFTDGSRPYGGFTASYTSSE---DAVCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEW 2601 Query: 70 IIEAAPRQ---CIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNP--PV 124 + + P Q I ++F++ Y +E +C+FD +E R G P++ R CG P P+ Sbjct: 2602 TL-SNPNQGNSSISIHFEDFY-LESHQDCQFDVLEFRVGDAD-GPLMWRLCGPSKPTLPL 2658 Query: 125 IKSSGRFLWIKFFADGELESMGFSARYNFT 154 + + +WI F + +E +GF A+Y+FT Sbjct: 2659 VIPYSQ-VWIHFVTNERVEHIGFHAKYSFT 2687 Score = 54.3 bits (129), Expect = 4e-08 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG T + + G FTSP YP YP + C +++ A + + + F SI+ +C ++ Sbjct: 3511 CGG-TLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINF-YFISIDDPGDCVQNY 3568 Query: 100 IEVRDGPFGFSPIIGRFCGQQN--PPVIKSSGRFLWIKFFAD 139 + + DGP SP G +CG P + SS + ++IKF AD Sbjct: 3569 LTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQ-VFIKFHAD 3609 Score = 48.9 bits (115), Expect = 2e-06 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 6/114 (5%) Query: 38 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKF 97 ++CG EG +F P + R+C+Y+++ + I++ F ++ + Sbjct: 706 LRCGGNYTDPEGELFL-PELSGPFTHTRQCVYMMKQPQGEQIQINFTH-VELQCQSDSSQ 763 Query: 98 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 ++IEVRDG ++G+ CG IKS +WI+F D +E F A Y Sbjct: 764 NYIEVRDG----ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVY 813 Score = 46.6 bits (109), Expect = 9e-06 Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 10/108 (9%) Query: 47 AEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGP 106 A G SPNYPS Y + +C ++I + L F + + +EP C I DG Sbjct: 1516 APSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTD-FDLEPQDSC----IMAYDGL 1570 Query: 107 FGFSPIIGRFCGQQ---NPPVIKSSGRFLWIKFFADGELESMGFSARY 151 + R CG++ NP I SSG L+++F + ++ GF A++ Sbjct: 1571 SSTMSRLARTCGREQLANP--IVSSGNSLFLRFQSGPSRQNRGFRAQF 1616 Score = 46.2 bits (108), Expect = 1e-05 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 6/106 (5%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEP----SWECKFDHIEVRDG 105 G SPNYP +Y + C Y+IEA P + L F + +E + C D + + G Sbjct: 2929 GYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTF-VSFHLEARSAVTGSCVNDGVHIIRG 2987 Query: 106 PFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 S CG + P + +G L + F+++ ++ GF Y Sbjct: 2988 YSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKFSY 3032 Score = 44.3 bits (103), Expect = 4e-05 Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 4/119 (3%) Query: 39 QCGTWTKHAEGGIFTSPNYPS-KYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKF 97 QCG + G+ S +P+ Y + C + ++ + + F++ ++++ S C+ Sbjct: 2335 QCGGRVP-GQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFED-FNLQNSSGCEK 2392 Query: 98 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPE 156 D +E+ D + I+GR+CG P I +S ++F DG + + GF R+ + E Sbjct: 2393 DFVEIWDNHTSGN-ILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSME 2450 Score = 43.9 bits (102), Expect = 6e-05 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 5/91 (5%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 GI S YP+ Y ++ C + I A + F + +E C D++E+ DGP Sbjct: 1289 GILESIGYPNPYSENQHCNWTIRATTGNTVNYTF-LAFDLEHHINCSTDYLELYDGPRQ- 1346 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADG 140 +GR+CG PP ++ L + DG Sbjct: 1347 ---MGRYCGVDLPPPGSTTSSKLQVLLLTDG 1374 Score = 43.5 bits (101), Expect = 7e-05 Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 2/98 (2%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G SP +P YP + + + + E IE C +D + + DGP Sbjct: 1861 GKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEM-DIEEIQNCYYDKLRIYDGPSIH 1919 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGF 147 + +IG +CG Q S+G L F++D + GF Sbjct: 1920 ARLIGAYCGTQTES-FSSTGNSLTFHFYSDSSISGKGF 1956 Score = 40.0 bits (92), Expect = 8e-04 Identities = 22/91 (24%), Positives = 42/91 (46%), Gaps = 1/91 (1%) Query: 61 YPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQ 120 Y D C ++I+ + + + F + +E C + ++V DG + +GRFCG Sbjct: 494 YVHDVNCFWVIKTEMGKVLRITFTF-FRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGSS 552 Query: 121 NPPVIKSSGRFLWIKFFADGELESMGFSARY 151 P + SS L+ +++ GF+ R+ Sbjct: 553 LPHELLSSDNALYFHLYSEHLRNGRGFTVRW 583 Score = 40.0 bits (92), Expect = 8e-04 Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 7/142 (4%) Query: 13 LIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIE 72 L++ S + +G T TQ ++ CG H++ G SP++P +P + C + Sbjct: 2779 LVVTFNSDHSLQGGGFYATWNTQ-TLGCGG-IFHSDNGTIRSPHWPQNFPENSRCSWTAI 2836 Query: 73 AAPRQCIELYFDEKYSI-EPSWECKFDHIEVRDGPFGF-SPIIGRFCGQQNP-PVIKSSG 129 + +E+ FD + I +C+ ++V G ++ CG P PVI S Sbjct: 2837 THKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPSN 2896 Query: 130 RFLWIKFFADGELESMGFSARY 151 F + F E + GFSA + Sbjct: 2897 TFTAV--FQSQEAPAQGFSASF 2916 Score = 31.6 bits (70), Expect = 0.29 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 10/90 (11%) Query: 42 TWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIE-PSWECKFDHI 100 TWT +SPN P C ++I++ P Q +++ ++++ S +C +++ Sbjct: 3285 TWTPQN----ISSPNSSDPDVPFSICTWVIDSPPHQQVKITV---WALQLTSQDCTQNYL 3337 Query: 101 EVRDGPFGFSPIIGRFCGQQNP--PVIKSS 128 +++D P G +FCG+ PV SS Sbjct: 3338 QLQDSPQGHGNSRFQFCGRNASAVPVFYSS 3367 >gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] Length = 909 Score = 89.4 bits (220), Expect = 1e-18 Identities = 48/118 (40%), Positives = 64/118 (54%), Gaps = 2/118 (1%) Query: 35 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 93 Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81 Query: 94 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139 Score = 66.6 bits (161), Expect = 8e-12 Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 7/108 (6%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPS------WECKFDHIEVR 103 G SP +P KYP + +C + I A P+ I L F + +E +CK+D +++ Sbjct: 158 GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQF-LIFDLEHDPLQVGEGDCKYDWLDIW 216 Query: 104 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 DG P+IG++CG + P ++SS L + F D + GFSARY Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 >gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] Length = 901 Score = 89.4 bits (220), Expect = 1e-18 Identities = 48/118 (40%), Positives = 64/118 (54%), Gaps = 2/118 (1%) Query: 35 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 93 Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81 Query: 94 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139 Score = 66.6 bits (161), Expect = 8e-12 Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 7/108 (6%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPS------WECKFDHIEVR 103 G SP +P KYP + +C + I A P+ I L F + +E +CK+D +++ Sbjct: 158 GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQF-LIFDLEHDPLQVGEGDCKYDWLDIW 216 Query: 104 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 DG P+IG++CG + P ++SS L + F D + GFSARY Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 >gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] Length = 931 Score = 89.4 bits (220), Expect = 1e-18 Identities = 48/118 (40%), Positives = 64/118 (54%), Gaps = 2/118 (1%) Query: 35 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 93 Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81 Query: 94 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139 Score = 66.6 bits (161), Expect = 8e-12 Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 7/108 (6%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPS------WECKFDHIEVR 103 G SP +P KYP + +C + I A P+ I L F + +E +CK+D +++ Sbjct: 158 GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQF-LIFDLEHDPLQVGEGDCKYDWLDIW 216 Query: 104 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 DG P+IG++CG + P ++SS L + F D + GFSARY Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 >gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] Length = 555 Score = 89.4 bits (220), Expect = 1e-18 Identities = 48/118 (40%), Positives = 64/118 (54%), Gaps = 2/118 (1%) Query: 35 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 93 Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81 Query: 94 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139 Score = 66.6 bits (161), Expect = 8e-12 Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 7/108 (6%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPS------WECKFDHIEVR 103 G SP +P KYP + +C + I A P+ I L F + +E +CK+D +++ Sbjct: 158 GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQF-LIFDLEHDPLQVGEGDCKYDWLDIW 216 Query: 104 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 DG P+IG++CG + P ++SS L + F D + GFSARY Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 >gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] Length = 906 Score = 89.4 bits (220), Expect = 1e-18 Identities = 48/118 (40%), Positives = 64/118 (54%), Gaps = 2/118 (1%) Query: 35 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 93 Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81 Query: 94 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139 Score = 66.6 bits (161), Expect = 8e-12 Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 7/108 (6%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPS------WECKFDHIEVR 103 G SP +P KYP + +C + I A P+ I L F + +E +CK+D +++ Sbjct: 158 GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQF-LIFDLEHDPLQVGEGDCKYDWLDIW 216 Query: 104 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 DG P+IG++CG + P ++SS L + F D + GFSARY Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 >gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] Length = 926 Score = 89.4 bits (220), Expect = 1e-18 Identities = 48/118 (40%), Positives = 64/118 (54%), Gaps = 2/118 (1%) Query: 35 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 93 Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81 Query: 94 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139 Score = 66.6 bits (161), Expect = 8e-12 Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 7/108 (6%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPS------WECKFDHIEVR 103 G SP +P KYP + +C + I A P+ I L F + +E +CK+D +++ Sbjct: 158 GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQF-LIFDLEHDPLQVGEGDCKYDWLDIW 216 Query: 104 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 DG P+IG++CG + P ++SS L + F D + GFSARY Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 >gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo sapiens] Length = 986 Score = 89.0 bits (219), Expect = 2e-18 Identities = 39/102 (38%), Positives = 63/102 (61%), Gaps = 1/102 (0%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G TSPN+P KYP +EC + I + P ++L F E IE EC +DH+EV DG Sbjct: 756 GTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEM-DIESQPECAYDHLEVFDGRDAK 814 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +P++GRFCG + P + ++G ++++F++D ++ GF A + Sbjct: 815 APVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856 Score = 84.7 bits (208), Expect = 3e-17 Identities = 44/112 (39%), Positives = 63/112 (56%), Gaps = 2/112 (1%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG K G I SPNYP Y P + CI+ I+ + + L F + + IE C +D+ Sbjct: 435 CGGDVKKDYGHI-QSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF-QSFEIERHDSCAYDY 492 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +EVRDG S +IGR+CG + P IKS+ LW+KF +DG + GF+ + Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544 Score = 75.9 bits (185), Expect = 1e-14 Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 2/112 (1%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + G I TSP +P +YPP++ CI+ + A + I L FD + E + CK+D Sbjct: 591 CGGFLTKLNGSI-TSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDF-FETEGNDVCKYDF 648 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +EVR G S + G+FCG + P VI S + ++F +D + GF A + Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700 Score = 68.9 bits (167), Expect = 2e-12 Identities = 40/116 (34%), Positives = 59/116 (50%), Gaps = 2/116 (1%) Query: 36 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 95 K CG + + G F+SP YP+ Y C++ I P + I L F + S C Sbjct: 318 KCPACGETLQDSTGN-FSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS-LDLYRSRLC 375 Query: 96 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +D++EVRDG + +P+ GRFCG + P I S+ LW++F + GF A Y Sbjct: 376 WYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431 Score = 63.5 bits (153), Expect = 7e-11 Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 12/136 (8%) Query: 23 KKGTEKQTTSETQKSVQCGTWTK----HAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQC 78 +KG + +E V+ TK HA+ G + YP +C ++I A Sbjct: 849 RKGFQASHATECGGQVRADVKTKDLYSHAQFG-------DNNYPGGVDCEWVIVAEEGYG 901 Query: 79 IELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFA 138 +EL F + + +E +C +D++E+ DG +P +GR+CG P + S+G + +KF + Sbjct: 902 VELVF-QTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS 960 Query: 139 DGELESMGFSARYNFT 154 D + GF RY T Sbjct: 961 DDTITKKGFHLRYTST 976 >gi|66864913 neuropilin 1 isoform c [Homo sapiens] Length = 609 Score = 88.6 bits (218), Expect = 2e-18 Identities = 47/114 (41%), Positives = 65/114 (57%), Gaps = 2/114 (1%) Query: 39 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSWECKF 97 +CG K G TSP YP Y P +C ++I+A P Q I + F+ + +E +CK+ Sbjct: 26 KCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKY 84 Query: 98 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 D++EV DG G+FCG+ PP + SSG FL+IKF +D E GFS RY Sbjct: 85 DYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRY 138 Score = 78.2 bits (191), Expect = 3e-15 Identities = 42/109 (38%), Positives = 58/109 (53%), Gaps = 7/109 (6%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWE------CKFDHIEVR 103 G+ SP +P KYP EC YI+ A I L F E + +EP C++D +E+ Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDRLEIW 214 Query: 104 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 DG P IGR+CGQ+ P I+SS L + F+ D + GFSA Y+ Sbjct: 215 DGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263 >gi|66912178 neuropilin 1 isoform b [Homo sapiens] Length = 644 Score = 88.6 bits (218), Expect = 2e-18 Identities = 47/114 (41%), Positives = 65/114 (57%), Gaps = 2/114 (1%) Query: 39 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSWECKF 97 +CG K G TSP YP Y P +C ++I+A P Q I + F+ + +E +CK+ Sbjct: 26 KCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKY 84 Query: 98 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 D++EV DG G+FCG+ PP + SSG FL+IKF +D E GFS RY Sbjct: 85 DYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRY 138 Score = 78.2 bits (191), Expect = 3e-15 Identities = 42/109 (38%), Positives = 58/109 (53%), Gaps = 7/109 (6%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWE------CKFDHIEVR 103 G+ SP +P KYP EC YI+ A I L F E + +EP C++D +E+ Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDRLEIW 214 Query: 104 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 DG P IGR+CGQ+ P I+SS L + F+ D + GFSA Y+ Sbjct: 215 DGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263 >gi|182508169 neuropilin 1 isoform a [Homo sapiens] Length = 923 Score = 88.6 bits (218), Expect = 2e-18 Identities = 47/114 (41%), Positives = 65/114 (57%), Gaps = 2/114 (1%) Query: 39 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSWECKF 97 +CG K G TSP YP Y P +C ++I+A P Q I + F+ + +E +CK+ Sbjct: 26 KCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKY 84 Query: 98 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 D++EV DG G+FCG+ PP + SSG FL+IKF +D E GFS RY Sbjct: 85 DYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRY 138 Score = 78.2 bits (191), Expect = 3e-15 Identities = 42/109 (38%), Positives = 58/109 (53%), Gaps = 7/109 (6%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWE------CKFDHIEVR 103 G+ SP +P KYP EC YI+ A I L F E + +EP C++D +E+ Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDRLEIW 214 Query: 104 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 DG P IGR+CGQ+ P I+SS L + F+ D + GFSA Y+ Sbjct: 215 DGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263 >gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo sapiens] Length = 730 Score = 84.7 bits (208), Expect = 3e-17 Identities = 44/112 (39%), Positives = 63/112 (56%), Gaps = 2/112 (1%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG K G I SPNYP Y P + CI+ I+ + + L F + + IE C +D+ Sbjct: 435 CGGDVKKDYGHI-QSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF-QSFEIERHDSCAYDY 492 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +EVRDG S +IGR+CG + P IKS+ LW+KF +DG + GF+ + Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544 Score = 75.9 bits (185), Expect = 1e-14 Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 2/112 (1%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + G I TSP +P +YPP++ CI+ + A + I L FD + E + CK+D Sbjct: 591 CGGFLTKLNGSI-TSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDF-FETEGNDVCKYDF 648 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +EVR G S + G+FCG + P VI S + ++F +D + GF A + Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700 Score = 68.9 bits (167), Expect = 2e-12 Identities = 40/116 (34%), Positives = 59/116 (50%), Gaps = 2/116 (1%) Query: 36 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 95 K CG + + G F+SP YP+ Y C++ I P + I L F + S C Sbjct: 318 KCPACGETLQDSTGN-FSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS-LDLYRSRLC 375 Query: 96 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +D++EVRDG + +P+ GRFCG + P I S+ LW++F + GF A Y Sbjct: 376 WYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431 >gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo sapiens] Length = 823 Score = 84.7 bits (208), Expect = 3e-17 Identities = 44/112 (39%), Positives = 63/112 (56%), Gaps = 2/112 (1%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG K G I SPNYP Y P + CI+ I+ + + L F + + IE C +D+ Sbjct: 435 CGGDVKKDYGHI-QSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF-QSFEIERHDSCAYDY 492 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +EVRDG S +IGR+CG + P IKS+ LW+KF +DG + GF+ + Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544 Score = 75.9 bits (185), Expect = 1e-14 Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 2/112 (1%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + G I TSP +P +YPP++ CI+ + A + I L FD + E + CK+D Sbjct: 591 CGGFLTKLNGSI-TSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDF-FETEGNDVCKYDF 648 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +EVR G S + G+FCG + P VI S + ++F +D + GF A + Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700 Score = 68.9 bits (167), Expect = 2e-12 Identities = 40/116 (34%), Positives = 59/116 (50%), Gaps = 2/116 (1%) Query: 36 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 95 K CG + + G F+SP YP+ Y C++ I P + I L F + S C Sbjct: 318 KCPACGETLQDSTGN-FSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS-LDLYRSRLC 375 Query: 96 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +D++EVRDG + +P+ GRFCG + P I S+ LW++F + GF A Y Sbjct: 376 WYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431 >gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens] Length = 449 Score = 77.8 bits (190), Expect = 3e-15 Identities = 53/143 (37%), Positives = 73/143 (51%), Gaps = 13/143 (9%) Query: 15 ILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYP-SKYPPDRECIYIIEA 73 +L SG GTE Q CG + A+G + T+PN+P S YPP C + I A Sbjct: 143 LLWYSGRATSGTEHQF---------CGGRLEKAQGTL-TTPNWPESDYPPGISCSWHIIA 192 Query: 74 APRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF-SPIIGRFCGQQNPPVIKSSGRFL 132 P Q I L F EK+ +EP C++D + V +G S +G+FCG P I S G L Sbjct: 193 PPDQVIALTF-EKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNEL 251 Query: 133 WIKFFADGELESMGFSARYNFTP 155 ++F +D + + GFSA Y P Sbjct: 252 LVQFVSDLSVTADGFSASYKTLP 274 Score = 59.7 bits (143), Expect = 1e-09 Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 2/124 (1%) Query: 29 QTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYS 88 QT + T+ CG K E G S +P+ YPP++ECI+ I Q + L F + Sbjct: 26 QTPNYTRPVFLCGGDVK-GESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSF-RVFD 83 Query: 89 IEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFS 148 +E C++D +EV G +GRFCG P + + G + ++ D GF Sbjct: 84 LELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFL 143 Query: 149 ARYN 152 Y+ Sbjct: 144 LWYS 147 >gi|13899255 membrane frizzled-related protein [Homo sapiens] Length = 579 Score = 76.3 bits (186), Expect = 1e-14 Identities = 46/133 (34%), Positives = 68/133 (51%), Gaps = 6/133 (4%) Query: 19 SGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQC 78 + T KG ++ S + +S CG G F+SPNYP YPP+ C++ I+ A Sbjct: 124 AAGTPKGQQESGVSPSPQST-CGGLLSGPRG-FFSSPNYPDPYPPNTHCVWHIQVATDHA 181 Query: 79 IELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFA 138 I+L E SIE C FD +E+ P G P++ R CG+ PP + ++ L + F + Sbjct: 182 IQLKI-EALSIESVASCLFDRLELSPEPEG--PLL-RVCGRVPPPTLNTNASHLLVVFVS 237 Query: 139 DGELESMGFSARY 151 D +E GF A Y Sbjct: 238 DSSVEGFGFHAWY 250 Score = 70.1 bits (170), Expect = 7e-13 Identities = 40/103 (38%), Positives = 56/103 (54%), Gaps = 2/103 (1%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRD-GPFG 108 G F++P+Y +YP C + I IEL F +S+E ECKFD++EV + G Sbjct: 310 GTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQF-HNFSLEAQDECKFDYVEVYETSSSG 368 Query: 109 FSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 ++GRFCG + PP + SS L + F D + S GFSA Y Sbjct: 369 AFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 411 >gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] Length = 3565 Score = 74.3 bits (181), Expect = 4e-14 Identities = 38/105 (36%), Positives = 54/105 (51%), Gaps = 5/105 (4%) Query: 47 AEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGP 106 A G+ P +P Y C +IIEA P I++ FD + E +D +EVRDGP Sbjct: 765 ASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQT-----EVNYDTLEVRDGP 819 Query: 107 FGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 SP+IG + G Q P + S+G F+++ F D S+GF Y Sbjct: 820 ASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHY 864 Score = 71.2 bits (173), Expect = 3e-13 Identities = 37/106 (34%), Positives = 59/106 (55%), Gaps = 5/106 (4%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G+ SPNYP YPP +EC + ++ P I L F + +++EPS +D + + +G Sbjct: 1461 GVILSPNYPQPYPPGKECDWRVKVNPDFVIALIF-KSFNMEPS----YDFLHIYEGEDSN 1515 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 155 SP+IG + G Q P I+SSG L++ F +D + GF+ + P Sbjct: 1516 SPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKP 1561 Score = 63.5 bits (153), Expect = 7e-11 Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 5/105 (4%) Query: 47 AEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGP 106 A GI SPNYP +Y + C+++I + P I L F++ + +EP +FD + V+D Sbjct: 591 ASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFND-FDVEP----QFDFLAVKDDG 645 Query: 107 FGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 ++G F G + P + SSG + ++F +D GF+ Y Sbjct: 646 ISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITY 690 Score = 56.6 bits (135), Expect = 8e-09 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 5/103 (4%) Query: 49 GGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFG 108 GG+ SP +P YP + +C + I + F + S E D +E+++GP+ Sbjct: 1983 GGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQF-----LNFSTEANHDFLEIQNGPYH 2037 Query: 109 FSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 SP+IG+F G P + S+ I F++D GF Y Sbjct: 2038 TSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAY 2080 Score = 54.3 bits (129), Expect = 4e-08 Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 5/114 (4%) Query: 39 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFD 98 +CG A G SP YP+ Y + C +IIEA P + I L+F I E D Sbjct: 1277 ECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHF-----IVFDTEMAHD 1331 Query: 99 HIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 ++V DGP ++ + G P I S+ L ++F +D + GFS +++ Sbjct: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFS 1385 Score = 48.5 bits (114), Expect = 2e-06 Identities = 38/120 (31%), Positives = 51/120 (42%), Gaps = 6/120 (5%) Query: 36 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 95 K CG + G I SP +P YP C +II R I+L F +++E Sbjct: 28 KGQNCGGLVQGPNGTI-ESPGFPHGYPNYANCTWIIITGERNRIQLSF-HTFALEED--- 82 Query: 96 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 155 FD + V DG + R G Q P I S+G L + F D + + GF A Y P Sbjct: 83 -FDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLP 141 Score = 48.1 bits (113), Expect = 3e-06 Identities = 42/140 (30%), Positives = 61/140 (43%), Gaps = 13/140 (9%) Query: 18 LSGATKK----GTEKQTTSETQKSV-QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIE 72 L GATK G + ++ + V +CG K EG + SPN+PS Y + ECIY IE Sbjct: 1078 LEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLL-SPNFPSNYDNNHECIYKIE 1136 Query: 73 AAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFC-GQQNPPVIKSSGRF 131 + I L E D ++V DG S +G F + ++ S+ Sbjct: 1137 TEAGKGIHLRTRSFQLFEG------DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNH 1190 Query: 132 LWIKFFADGELESMGFSARY 151 LW++F +G GF Y Sbjct: 1191 LWLEFNTNGSDTDQGFQLTY 1210 Score = 47.8 bits (112), Expect = 4e-06 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 9/115 (7%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSWECKFD 98 CG+ G+ TSPNYP +Y + C+++I P + I+L F+E + +E +D Sbjct: 412 CGS-NLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEE-FELERG----YD 465 Query: 99 HIEVRD-GPFGFS-PIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 + V D G G + ++ G P +I S +W+ +D + S GF A Y Sbjct: 466 TLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVY 520 Score = 46.2 bits (108), Expect = 1e-05 Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 5/102 (4%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G SP YP Y + CI+ I I++ ++ E +W D +E+ DG Sbjct: 1812 GTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVIS-FATEQNW----DSLEIHDGGDVT 1866 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +P +G F G P ++ S+ L++ F +D + + GF Y Sbjct: 1867 APRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEY 1908 Score = 46.2 bits (108), Expect = 1e-05 Identities = 32/106 (30%), Positives = 46/106 (43%), Gaps = 12/106 (11%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G+ SP YP Y + C + I+ P I ++ D S E +FD +EV DG G Sbjct: 2331 GVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQS-----EKQFDALEVFDGSSGQ 2385 Query: 110 SPII----GRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 SP++ G Q N S L++++ D GF RY Sbjct: 2386 SPLLVVLSGNHTEQSN---FTSRSNQLYLRWSTDHATSKKGFKIRY 2428 Score = 44.7 bits (104), Expect = 3e-05 Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + ++ G SP +P +YP ++CI++I P + + F + E D+ Sbjct: 2147 CG-YNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQT-----EAVNDY 2200 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFAD 139 I V DGP SP +G F G SS + +KF +D Sbjct: 2201 IAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240 Score = 37.4 bits (85), Expect = 0.005 Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 10/112 (8%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + I +SP++PS+Y + +C + I A P I L F + + +E ++ F Sbjct: 208 CGGTLRGTSSSI-SSPHFPSEYENNADCTWTILAEPGDTIALVFTD-FQLEEGYD--FLE 263 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 I + P + G P + SS +L + F +D GF+A++ Sbjct: 264 ISGTEAPSIW------LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQF 309 Score = 35.4 bits (80), Expect = 0.020 Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 12/117 (10%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + + G + SP +P YP C + IE + + +++ F + +E S D+ Sbjct: 931 CGGYIQGKSGTVL-SPGFPDFYPNSLNCTWTIEVSHGKGVQMIF-HTFHLESS----HDY 984 Query: 100 IEV-RDGPFGFSPIIGRFCGQQNPPVIKSS--GRF-LWIKFFADGELESMGFSARYN 152 + + DG FS + R G P IK+ G F ++F +D + GF+ ++ Sbjct: 985 LLITEDG--SFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFS 1039 Score = 29.3 bits (64), Expect = 1.4 Identities = 24/111 (21%), Positives = 43/111 (38%), Gaps = 15/111 (13%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIEL----YFDEKYSIEPSWECKFDHIEVRDG 105 G+ SPNYP Y + C+Y I P++ + YF + D E+ DG Sbjct: 1635 GVVLSPNYPHNYTAGQICLYSI-TVPKEFVVFGQFAYFQTALN---------DLAELFDG 1684 Query: 106 PFGFSPIIGRFCGQQNPPVIK-SSGRFLWIKFFADGELESMGFSARYNFTP 155 + ++ G + + ++ + ++F A + GF Y P Sbjct: 1685 THAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVP 1735 >gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] Length = 3487 Score = 72.8 bits (177), Expect = 1e-13 Identities = 38/106 (35%), Positives = 57/106 (53%), Gaps = 5/106 (4%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G+ SPNYP YPP +EC + + +P I L F+ +++EP +D + + DG Sbjct: 1454 GVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNI-FNLEPG----YDFLHIYDGRDSL 1508 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 155 SP+IG F G Q P I+SS L++ F +D + + GF Y P Sbjct: 1509 SPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENP 1554 Score = 63.5 bits (153), Expect = 7e-11 Identities = 34/102 (33%), Positives = 52/102 (50%), Gaps = 5/102 (4%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G+ SPNYP Y C+++I A P I L F++ +EP +FD + ++DG Sbjct: 587 GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFND-IDVEP----QFDFLVIKDGATAE 641 Query: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +P++G F G Q P I SSG ++F D GF+ + Sbjct: 642 APVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITF 683 Score = 61.6 bits (148), Expect = 3e-10 Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 6/129 (4%) Query: 23 KKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELY 82 K+G+ ++ + CG G I SP +P Y C ++IEA P I++ Sbjct: 735 KEGSVVWNSAVLRCEAPCGGHLTSPSGTIL-SPGWPGFYKDALSCAWVIEAQPGYPIKIT 793 Query: 83 FDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGEL 142 FD + E +D +EVRDG +P+IG + G Q P + S+ +L++ F D Sbjct: 794 FDRFKT-----EVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSH 848 Query: 143 ESMGFSARY 151 +GF RY Sbjct: 849 SDIGFQLRY 857 Score = 56.2 bits (134), Expect = 1e-08 Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 6/113 (5%) Query: 39 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFD 98 QCG + EG + SP +P YP + +C + I + F +S EP+ D Sbjct: 1967 QCGGTVEEMEG-VILSPGFPGNYPSNMDCSWKIALPVGFGAHIQF-LNFSTEPN----HD 2020 Query: 99 HIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +IE+R+GP+ S ++GRF G + P + S+ + F +D GF Y Sbjct: 2021 YIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEY 2073 Score = 54.3 bits (129), Expect = 4e-08 Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 6/104 (5%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G+ S +YP YP + C +++ P I L + S E ++D E+ DGP G Sbjct: 2366 GVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLS-----EKQYDEFEIFDGPSGQ 2420 Query: 110 SPIIGRFCGQQNPP-VIKSSGRFLWIKFFADGELESMGFSARYN 152 SP++ G + P ++ SS +++++ +D GF RY+ Sbjct: 2421 SPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYS 2464 Score = 53.5 bits (127), Expect = 7e-08 Identities = 35/105 (33%), Positives = 54/105 (51%), Gaps = 8/105 (7%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSWECKFDHIEVRDG--P 106 GI TSPN+P +Y + C++II A P + I+L F+E + +E +D + V DG Sbjct: 414 GIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEE-FDLERG----YDTLTVGDGGQD 468 Query: 107 FGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 ++ G P +I S+ +W+ F DG S+GF A Y Sbjct: 469 GDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASY 513 Score = 51.2 bits (121), Expect = 3e-07 Identities = 34/114 (29%), Positives = 51/114 (44%), Gaps = 5/114 (4%) Query: 42 TWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIE 101 T+ H G SP +P YP C + I A + I+L F + +++E FD + Sbjct: 27 TFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVF-QSFALEED----FDVLS 81 Query: 102 VRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 155 V DGP + R G Q P I S+ L ++ +D + + GF A Y P Sbjct: 82 VFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLP 135 Score = 48.1 bits (113), Expect = 3e-06 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 8/115 (6%) Query: 39 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFD 98 +CG +G + SPN+P Y + ECIY I+ P + I+L + + E S + D Sbjct: 1097 ECGNSVTGTQGTLL-SPNFPVNYNNNHECIYSIQTQPGKGIQL---KARAFELS---EGD 1149 Query: 99 HIEVRDGPFGFSPIIGRFCGQQNPPV-IKSSGRFLWIKFFADGELESMGFSARYN 152 ++V DG + ++G F + V + S+ LW+ F D E S GF ++ Sbjct: 1150 VLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFS 1204 Score = 46.6 bits (109), Expect = 9e-06 Identities = 38/112 (33%), Positives = 54/112 (48%), Gaps = 10/112 (8%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG T + GI +SP++PS+Y + +C + I A I L F I+ E +D Sbjct: 202 CGG-TLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVF-----IDFQLEDGYDF 255 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +EV G G S F G P + SS +L + F +DG GFSA+Y Sbjct: 256 LEV-TGTEGSSL---WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQY 303 Score = 43.5 bits (101), Expect = 7e-05 Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 6/114 (5%) Query: 38 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKF 97 V CG G I SP +P Y C++ I I++ + E +W Sbjct: 1794 VPCGGNLTERRGTIL-SPGFPEPYLNSLNCVWKIVVPEGAGIQIQV-VSFVTEQNW---- 1847 Query: 98 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 D +EV DG ++G F G P ++ S+ L++ F++D + + GF Y Sbjct: 1848 DSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEY 1901 Score = 42.0 bits (97), Expect = 2e-04 Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 9/115 (7%) Query: 38 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKF 97 V CG + G ++ SP +PS Y ++C+++I + L EPS Sbjct: 2180 VPCGGNITSSNGTVY-SPGFPSPYSSSQDCVWLITVPIGHGVRLNL-SLLQTEPSG---- 2233 Query: 98 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFAD---GELESMGFSA 149 D I + DGP +P +G F ++SS + +KF D G + ++ FSA Sbjct: 2234 DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSA 2288 Score = 40.0 bits (92), Expect = 8e-04 Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 5/114 (4%) Query: 39 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFD 98 +CG + G SP YP+ Y + CI+ IEA I L+F + E D Sbjct: 1270 ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHF-----LVFDTEEVHD 1324 Query: 99 HIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152 + + DGP ++ G P + S+ + ++F D GF+ +++ Sbjct: 1325 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFS 1378 Score = 33.9 bits (76), Expect = 0.057 Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 7/107 (6%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G+ SPNYP Y + C+Y + P+ + F + + D +EV DG Sbjct: 1628 GVVLSPNYPQNYTSGQICLYFV-TVPKDYV--VFGQFAFFHTALN---DVVEVHDGHSQH 1681 Query: 110 SPIIGRFCGQQNPPVIK-SSGRFLWIKFFADGELESMGFSARYNFTP 155 S ++ G + ++ + IKF A G + GF Y P Sbjct: 1682 SRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVP 1728 Score = 29.6 bits (65), Expect = 1.1 Identities = 26/116 (22%), Positives = 52/116 (44%), Gaps = 10/116 (8%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + + + G I SP +P YP + C +IIE + + + F + E D+ Sbjct: 924 CGGFIQGSSGTIL-SPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFH-----LESGHDY 977 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSS--GRF-LWIKFFADGELESMGFSARYN 152 + + + F+ + + G + P I + G F ++F +D + GF+ ++ Sbjct: 978 LLITENG-SFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFS 1032 >gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [Homo sapiens] Length = 380 Score = 70.9 bits (172), Expect = 4e-13 Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%) Query: 38 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIE--PSWEC 95 V+C G+ TSP++P+ YP EC+Y IE + L F++ + IE P C Sbjct: 183 VECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPC 242 Query: 96 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +D+I+++ GP ++G FCG++ P I + + I F +D E+ G+ Y Sbjct: 243 PYDYIKIKVGP----KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294 Score = 50.1 bits (118), Expect = 8e-07 Identities = 36/112 (32%), Positives = 53/112 (47%), Gaps = 15/112 (13%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G SP YP YP D E + I I+LYF +++E S+ C++D+++V Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYF-MHFNLESSYLCEYDYVKVETE---- 83 Query: 110 SPIIGRFCG------QQNP--PVIKSSGRFLWIKFFAD--GELESMGFSARY 151 ++ FCG +Q P V+ S G F+ I F +D E GF A Y Sbjct: 84 DQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHY 135 >gi|21264359 mannan-binding lectin serine protease 1 isoform 2 precursor [Homo sapiens] Length = 728 Score = 70.9 bits (172), Expect = 4e-13 Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%) Query: 38 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIE--PSWEC 95 V+C G+ TSP++P+ YP EC+Y IE + L F++ + IE P C Sbjct: 183 VECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPC 242 Query: 96 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +D+I+++ GP ++G FCG++ P I + + I F +D E+ G+ Y Sbjct: 243 PYDYIKIKVGP----KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294 Score = 50.1 bits (118), Expect = 8e-07 Identities = 36/112 (32%), Positives = 53/112 (47%), Gaps = 15/112 (13%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G SP YP YP D E + I I+LYF +++E S+ C++D+++V Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYF-MHFNLESSYLCEYDYVKVETE---- 83 Query: 110 SPIIGRFCG------QQNP--PVIKSSGRFLWIKFFAD--GELESMGFSARY 151 ++ FCG +Q P V+ S G F+ I F +D E GF A Y Sbjct: 84 DQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHY 135 >gi|21264357 mannan-binding lectin serine protease 1 isoform 1 precursor [Homo sapiens] Length = 699 Score = 70.9 bits (172), Expect = 4e-13 Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%) Query: 38 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIE--PSWEC 95 V+C G+ TSP++P+ YP EC+Y IE + L F++ + IE P C Sbjct: 183 VECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPC 242 Query: 96 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +D+I+++ GP ++G FCG++ P I + + I F +D E+ G+ Y Sbjct: 243 PYDYIKIKVGP----KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294 Score = 50.1 bits (118), Expect = 8e-07 Identities = 36/112 (32%), Positives = 53/112 (47%), Gaps = 15/112 (13%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109 G SP YP YP D E + I I+LYF +++E S+ C++D+++V Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYF-MHFNLESSYLCEYDYVKVETE---- 83 Query: 110 SPIIGRFCG------QQNP--PVIKSSGRFLWIKFFAD--GELESMGFSARY 151 ++ FCG +Q P V+ S G F+ I F +D E GF A Y Sbjct: 84 DQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHY 135 >gi|72384339 CUB domain containing protein 2 [Homo sapiens] Length = 449 Score = 70.1 bits (170), Expect = 7e-13 Identities = 43/124 (34%), Positives = 65/124 (52%), Gaps = 9/124 (7%) Query: 32 SETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEP 91 ++ + V+CG A G F+SPN+P YP + EC ++I A + L F + +E Sbjct: 22 AQAMEGVKCGG-VLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTF-HAFDLEY 79 Query: 92 SWECKFDHIEVRDGPFGFSP----IIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGF 147 C FD +E+ +G SP ++GRFCG+ PP SS + + F +D + S GF Sbjct: 80 HDTCSFDFLEIYNGA---SPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGF 136 Query: 148 SARY 151 SA Y Sbjct: 137 SAGY 140 Score = 69.3 bits (168), Expect = 1e-12 Identities = 42/118 (35%), Positives = 60/118 (50%), Gaps = 7/118 (5%) Query: 35 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWE 94 QK V G T G+ TSP YP+ YP EC ++I AA ++L F + + +E + E Sbjct: 141 QKDVCGGVLT--GLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVD-FQVEGNEE 197 Query: 95 CKFDHIEVRDGPFGFSPIIG-RFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 C +D++ V GP P G +CG PP + S G L + F +D + GF A Y Sbjct: 198 CTYDYVAVLGGP---GPTRGHHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYY 252 Score = 65.1 bits (157), Expect = 2e-11 Identities = 35/105 (33%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSW---ECKFDHIEVRDGP 106 G F+SP YPS YP + C + I P ++++F + EP+ C FDH+ DG Sbjct: 266 GNFSSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGA 325 Query: 107 FGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151 +P++G +CG PP + SS L + D GFS Y Sbjct: 326 SEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAY 370 >gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] Length = 1662 Score = 69.3 bits (168), Expect = 1e-12 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 3/126 (2%) Query: 30 TTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSI 89 TT+ + S CG + +A G F+SP+YP+ YP + +C++ IE I L F + Sbjct: 1005 TTTTARPSSNCGGFLFYASG-TFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGF-SNLKL 1062 Query: 90 EPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSA 149 E C FD++E+ DG S ++G+ C + SS + I F +D ++ GF A Sbjct: 1063 EAHHNCSFDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLA 1121 Query: 150 RYNFTP 155 YN P Sbjct: 1122 WYNSFP 1127 Score = 68.2 bits (165), Expect = 3e-12 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 5/116 (4%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + G F+SP YP YP + +C++ IE + + F + ++ C +D+ Sbjct: 1257 CGGFLSQPSGD-FSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRD---VQLEGGCNYDY 1312 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 155 IEV DGP+ SP+I R C SS F+ I+F +D + GF A Y +P Sbjct: 1313 IEVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEYYSSP 1367 >gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] Length = 1788 Score = 69.3 bits (168), Expect = 1e-12 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 3/126 (2%) Query: 30 TTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSI 89 TT+ + S CG + +A G F+SP+YP+ YP + +C++ IE I L F + Sbjct: 1131 TTTTARPSSNCGGFLFYASG-TFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGF-SNLKL 1188 Query: 90 EPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSA 149 E C FD++E+ DG S ++G+ C + SS + I F +D ++ GF A Sbjct: 1189 EAHHNCSFDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLA 1247 Query: 150 RYNFTP 155 YN P Sbjct: 1248 WYNSFP 1253 Score = 68.2 bits (165), Expect = 3e-12 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 5/116 (4%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + G F+SP YP YP + +C++ IE + + F + ++ C +D+ Sbjct: 1383 CGGFLSQPSGD-FSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRD---VQLEGGCNYDY 1438 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 155 IEV DGP+ SP+I R C SS F+ I+F +D + GF A Y +P Sbjct: 1439 IEVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEYYSSP 1493 >gi|148539844 deleted in malignant brain tumors 1 isoform c precursor [Homo sapiens] Length = 2403 Score = 69.3 bits (168), Expect = 1e-12 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 3/126 (2%) Query: 30 TTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSI 89 TT+ + S CG + +A G F+SP+YP+ YP + +C++ IE I L F + Sbjct: 1746 TTTTARPSSNCGGFLFYASG-TFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGF-SNLKL 1803 Query: 90 EPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSA 149 E C FD++E+ DG S ++G+ C + SS + I F +D ++ GF A Sbjct: 1804 EAHHNCSFDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLA 1862 Query: 150 RYNFTP 155 YN P Sbjct: 1863 WYNSFP 1868 Score = 68.2 bits (165), Expect = 3e-12 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 5/116 (4%) Query: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99 CG + G F+SP YP YP + +C++ IE + + F + ++ C +D+ Sbjct: 1998 CGGFLSQPSGD-FSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRD---VQLEGGCNYDY 2053 Query: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 155 IEV DGP+ SP+I R C SS F+ I+F +D + GF A Y +P Sbjct: 2054 IEVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEYYSSP 2108 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.138 0.441 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,102,744 Number of Sequences: 37866 Number of extensions: 320993 Number of successful extensions: 866 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 82 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 458 Number of HSP's gapped (non-prelim): 247 length of query: 156 length of database: 18,247,518 effective HSP length: 94 effective length of query: 62 effective length of database: 14,688,114 effective search space: 910663068 effective search space used: 910663068 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.