Search of human proteins with 20270331

Search of human proteins with 20270331

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20270331 transmembrane protein 45B [Homo sapiens]
         (275 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20270331 transmembrane protein 45B [Homo sapiens]                  576   e-165
gi|8922243 transmembrane protein 45A [Homo sapiens]                   243   2e-64
gi|110624783 putative membrane protein HE9 [Homo sapiens]              86   5e-17
gi|4505835 polycystin 2 [Homo sapiens]                                 30   2.3  
gi|122937323 transmembrane protein 202 [Homo sapiens]                  28   6.7  

>gi|20270331 transmembrane protein 45B [Homo sapiens]
          Length = 275

 Score =  576 bits (1484), Expect = e-165
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MANFKGHALPGSFFLIIGLCWSVKYPLKYFSHTRKNSPLHYYQRLEIVEAAIRTLFSVTG 60
           MANFKGHALPGSFFLIIGLCWSVKYPLKYFSHTRKNSPLHYYQRLEIVEAAIRTLFSVTG
Sbjct: 1   MANFKGHALPGSFFLIIGLCWSVKYPLKYFSHTRKNSPLHYYQRLEIVEAAIRTLFSVTG 60

Query: 61  ILAEQFVPDGPHLHLYHENHWIKLMNWQHSTMYLFFAVSGIVDMLTYLVSHVPLGVDRLV 120
           ILAEQFVPDGPHLHLYHENHWIKLMNWQHSTMYLFFAVSGIVDMLTYLVSHVPLGVDRLV
Sbjct: 61  ILAEQFVPDGPHLHLYHENHWIKLMNWQHSTMYLFFAVSGIVDMLTYLVSHVPLGVDRLV 120

Query: 121 MAVAVFMEGFLFYYHVHNRPPLDQHIHSLLLYALFGGCVSISLEVIFRDHIVLELFRTSL 180
           MAVAVFMEGFLFYYHVHNRPPLDQHIHSLLLYALFGGCVSISLEVIFRDHIVLELFRTSL
Sbjct: 121 MAVAVFMEGFLFYYHVHNRPPLDQHIHSLLLYALFGGCVSISLEVIFRDHIVLELFRTSL 180

Query: 181 IILQGTWFWQIGFVLFPPFGTPEWDQKDDANLMFITMCFCWHYLAALSIVAVNYSLVYCL 240
           IILQGTWFWQIGFVLFPPFGTPEWDQKDDANLMFITMCFCWHYLAALSIVAVNYSLVYCL
Sbjct: 181 IILQGTWFWQIGFVLFPPFGTPEWDQKDDANLMFITMCFCWHYLAALSIVAVNYSLVYCL 240

Query: 241 LTRMKRHGRGEIIGIQKLNSDDTYQTALLSGSDEE 275
           LTRMKRHGRGEIIGIQKLNSDDTYQTALLSGSDEE
Sbjct: 241 LTRMKRHGRGEIIGIQKLNSDDTYQTALLSGSDEE 275


>gi|8922243 transmembrane protein 45A [Homo sapiens]
          Length = 275

 Score =  243 bits (619), Expect = 2e-64
 Identities = 115/259 (44%), Positives = 169/259 (65%), Gaps = 7/259 (2%)

Query: 1   MANFKGHALPGSFFLIIGLCWSVKYPLKYFSHTRKNS----PLHYYQRLEIVEAAIRTLF 56
           M NF+GHALPG+FF IIGL W  K  LKY    +K +        + RLEI+E       
Sbjct: 1   MGNFRGHALPGTFFFIIGLWWCTKSILKYICKKQKRTCYLGSKTLFYRLEILEGITIVGM 60

Query: 57  SVTGILAEQFVPDGPHLHLYH--ENHWIKLMNWQHSTMYLFFAVSGIVDMLTYLVSHVPL 114
           ++TG+  EQF+P GPHL LY   + HW +L+ W H TMY FF + G+ D+L + +S +P+
Sbjct: 61  ALTGMAGEQFIPGGPHLMLYDYKQGHWNQLLGWHHFTMYFFFGLLGVADILCFTISSLPV 120

Query: 115 GVDRLVMAVAVFMEGFLFYYHVHNRPPLDQHIHSLLLYALFGGCVSISLEVIFRDHIVLE 174
            + +L+++ A+F+E F+FY H H R  LD  +H LL+  +F   +   LE + R++++LE
Sbjct: 121 SLTKLMLSNALFVEAFIFYNHTHGREMLDIFVHQLLVLVVFLTGLVAFLEFLVRNNVLLE 180

Query: 175 LFRTSLIILQGTWFWQIGFVLFPPFGTPEWDQKDDANLMFITMCFCWHYLAALSIVAVNY 234
           L R+SLI+LQG+WF+QIGFVL+PP G P WD  D  N++F+T+CFCWHY   + IV +NY
Sbjct: 181 LLRSSLILLQGSWFFQIGFVLYPPSGGPAWDLMDHENILFLTICFCWHYAVTIVIVGMNY 240

Query: 235 SLVYCLL-TRMKRHGRGEI 252
           + +  L+ +R+KR    E+
Sbjct: 241 AFITWLVKSRLKRLCSSEV 259


>gi|110624783 putative membrane protein HE9 [Homo sapiens]
          Length = 273

 Score = 85.5 bits (210), Expect = 5e-17
 Identities = 45/170 (26%), Positives = 87/170 (51%), Gaps = 5/170 (2%)

Query: 87  WQHSTMYLFFAVSGIVDMLTY-LVSHVPLGVDRLVMAVAVFMEGFLFYYHVHNRPPLDQH 145
           WQH TM++   ++G VD ++  ++    +G+++  + + ++    L   HV +   ++ H
Sbjct: 69  WQHLTMFILLTLNGCVDFMSKNVLPQRCVGLEKGTLVLIIYELLLLMVSHVKDSEGVELH 128

Query: 146 IHSLLLYALFGGCVSISLEVIFRDHIVLELFRTSLIILQGTWFWQIGFVLFPPFGTPEWD 205
           ++SLL+  +F   + ++ E+   +   L+L  T LI++ G+W  Q GF+L+ P     W 
Sbjct: 129 VYSLLILVVFLLLLVLTAELWAPNMCHLQLMETFLILMMGSWLMQAGFILYRPVSGYPWQ 188

Query: 206 QKDDANLMFITMCFCWHYLAALSIVAVNYSL----VYCLLTRMKRHGRGE 251
             D +++MF+T  FCWH +   S +   Y       +C    +K  G  E
Sbjct: 189 DDDISDIMFVTTFFCWHVMINASFLLGIYGFSSFWYHCFRPSLKLTGPKE 238


>gi|4505835 polycystin 2 [Homo sapiens]
          Length = 968

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 4/105 (3%)

Query: 117 DRLVMAVAVFMEGFLFYYHVHNRPPLDQHIHSLLLYALFGGCVSISLEVIFRDHIVLELF 176
           D  + A  +    F+FYY V     L+  IH L  +  F  C+ + + V+    I + ++
Sbjct: 470 DFFLAACEIIFCFFIFYYVVEEI--LEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIY 527

Query: 177 RTSLIILQGTWFWQIGFVLFPPFGTPEWDQKDDANLMFITMCFCW 221
           RTS + +   +        FP F    + Q    N+  +T+ F W
Sbjct: 528 RTSNVEVLLQFLEDQN--TFPNFEHLAYWQIQFNNIAAVTVFFVW 570


>gi|122937323 transmembrane protein 202 [Homo sapiens]
          Length = 273

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 12/33 (36%), Positives = 17/33 (51%), Gaps = 3/33 (9%)

Query: 81  WIKLMNWQHSTMYLFFAVSGIVDMLTYLVSHVP 113
           W   +NW     Y+F   +GI+ +L YL S  P
Sbjct: 191 WTYYLNWCSDIFYMF---AGIISLLNYLTSRSP 220


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.143    0.471 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,566,139
Number of Sequences: 37866
Number of extensions: 422324
Number of successful extensions: 931
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 924
Number of HSP's gapped (non-prelim): 5
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.