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Search of human proteins with 20149698
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20149698 l(3)mbt-like 2 [Homo sapiens]
(705 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20149698 l(3)mbt-like 2 [Homo sapiens] 1464 0.0
gi|158508476 mbt domain containing 1 [Homo sapiens] 703 0.0
gi|71274154 Scm-like with four mbt domains 2 [Homo sapiens] 249 8e-66
gi|53692193 Scm-like with four mbt domains 1 [Homo sapiens] 239 5e-63
gi|53692191 Scm-like with four mbt domains 1 [Homo sapiens] 239 5e-63
gi|53692195 Scm-like with four mbt domains 1 [Homo sapiens] 239 5e-63
gi|117938328 l(3)mbt-like isoform I [Homo sapiens] 192 1e-48
gi|117938330 l(3)mbt-like isoform II [Homo sapiens] 192 1e-48
gi|158138528 l(3)mbt-like 4 [Homo sapiens] 187 4e-47
gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens] 182 7e-46
gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens] 182 7e-46
gi|5174669 sex comb on midleg-like 2 [Homo sapiens] 130 4e-30
gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens] 129 7e-30
gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens] 129 7e-30
gi|148612879 polyhomeotic like 3 [Homo sapiens] 45 2e-04
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 45 3e-04
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 45 3e-04
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 45 3e-04
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 45 3e-04
gi|4504993 leukemia inhibitory factor receptor precursor [Homo s... 36 0.14
gi|189083786 leukemia inhibitory factor receptor precursor [Homo... 36 0.14
gi|39653325 PHD finger protein 20-like 1 isoform 3 [Homo sapiens] 35 0.24
gi|109134330 PHD finger protein 20-like 1 isoform 2 [Homo sapiens] 35 0.24
gi|111120331 PHD finger protein 20-like 1 isoform 1 [Homo sapiens] 35 0.24
gi|34996489 pleckstrin homology domain interacting protein [Homo... 35 0.24
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 35 0.31
gi|215422388 death-domain associated protein isoform a [Homo sap... 35 0.31
gi|215422366 death-domain associated protein isoform b [Homo sap... 35 0.31
gi|150418009 transforming, acidic coiled-coil containing protein... 34 0.53
gi|45827755 transforming, acidic coiled-coil containing protein ... 34 0.53
>gi|20149698 l(3)mbt-like 2 [Homo sapiens]
Length = 705
Score = 1464 bits (3789), Expect = 0.0
Identities = 705/705 (100%), Positives = 705/705 (100%)
Query: 1 MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDRE 60
MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDRE
Sbjct: 1 MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDRE 60
Query: 61 AGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSS 120
AGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSS
Sbjct: 61 AGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSS 120
Query: 121 NSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFD 180
NSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFD
Sbjct: 121 NSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFD 180
Query: 181 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAG 240
WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAG
Sbjct: 181 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAG 240
Query: 241 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR 300
YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR
Sbjct: 241 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR 300
Query: 301 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG 360
LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG
Sbjct: 301 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG 360
Query: 361 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA 420
DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA
Sbjct: 361 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA 420
Query: 421 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS 480
VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS
Sbjct: 421 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS 480
Query: 481 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM 540
SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM
Sbjct: 481 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM 540
Query: 541 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ 600
KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ
Sbjct: 541 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ 600
Query: 601 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI 660
LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI
Sbjct: 601 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI 660
Query: 661 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD 705
SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD
Sbjct: 661 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD 705
>gi|158508476 mbt domain containing 1 [Homo sapiens]
Length = 628
Score = 703 bits (1814), Expect = 0.0
Identities = 344/600 (57%), Positives = 421/600 (70%), Gaps = 21/600 (3%)
Query: 26 LFGGYDSFRSYNSSVGSESSSYLEESSEAENEDREAGELPTSPLHLLSPGTPRSLDGSGS 85
+F GYDS SS SS +E + E LP++ + + G + S
Sbjct: 1 MFDGYDSCSEDTSS-----------SSSSEESEEEVAPLPSNLPIIKNNGQVYTYPDGKS 49
Query: 86 EPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHK 145
A CEMCG+VG R+AF+SKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVL K
Sbjct: 50 GMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQK 109
Query: 146 AAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYD 205
AK+ A+ Q T L + T + GF WG ++ +S+ AAPV+CFKH P+
Sbjct: 110 QPLVAKLAAYAQYQAT--LQNQAKTKAAVSMEGFSWGNYINSNSFIAAPVTCFKHAPMGT 167
Query: 206 QWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTV 265
W D+ + ++VEV N+D LP++V+WIA +++ AGY LLRYEGFEND+ DFWCN+
Sbjct: 168 CWGDISENVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSGLDFWCNICGS 227
Query: 266 DVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQ 325
D+HP+GWCA + K LVPPRTI K+T+WK +L+KRL G++TLP DF K+ ESM+YPF+
Sbjct: 228 DIHPVGWCAASGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKP 287
Query: 326 GMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG-DSDDDFWCHMWSPLIHPVGWSRRV 384
MR+EVVDK + RTR+AVV++VIGGRLRL+YE+ D DDFWCHM SPLIH +GWSR +
Sbjct: 288 CMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSI 347
Query: 385 GHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGN 444
GH K S+ H D P+LF KV+ V G WF+EGMKLEAIDPLNL
Sbjct: 348 GHRFKRSDITKKQDGH-------FDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLST 400
Query: 445 ICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKGYE 504
ICVAT+ KVL DG+LMI +DG + DG DWFCYHA+S +IFP FC+ N IELTPP+GY
Sbjct: 401 ICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYT 460
Query: 505 AQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHR 564
F W +YL +T S AAP +LFN D PNHGF+VGMKLEAVDLMEPRLICVATV R++HR
Sbjct: 461 KLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHR 520
Query: 565 LLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKK 624
LL IHFDGW+ EYDQWVDCESPD+YPVGWC+LTGYQLQPP + A KKK K
Sbjct: 521 LLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRENQSASSKQKKKAK 580
Score = 81.6 bits (200), Expect = 2e-15
Identities = 93/322 (28%), Positives = 140/322 (43%), Gaps = 43/322 (13%)
Query: 214 MKVEVLNSDAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWC 273
M+VEV++ + +RV + SVI G R+ L YE E D + DFWC++ + +H IGW
Sbjct: 289 MRVEVVDKRHLCRTRVAVVESVI---GGRLRLVYEESE-DRTDDFWCHMHSPLIHHIGWS 344
Query: 274 AINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFH--IKMVESMKYPFRQGMRLEV 331
R+I +F + + K+ G P +K V+ F++GM+LE
Sbjct: 345 ----------RSIGHRFK--RSDITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEA 392
Query: 332 VDKSQVSRTRMAVVDTVIGGRLRLLYEDG----DSDDDFWCHMWSPLIHPVGWSRRVGHG 387
+D +S +A + V+ ++ DG D D F H SP I PVG+
Sbjct: 393 IDPLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCE----- 447
Query: 388 IKMSERRSDMAHHPT-------FRKIYCDAVPY-LFKKVRAVYTEGGWFEEGMKLEAIDP 439
I M E + R+ A P LF K V G F GMKLEA+D
Sbjct: 448 INMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNK--DVPNHG--FRVGMKLEAVDL 503
Query: 440 LNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTP 499
+ ICVATV +++ L I DG W S ++P +CQ +L P
Sbjct: 504 MEPRLICVATVTRII-HRLLRIHFDGWEEEYD-QWV--DCESPDLYPVGWCQLTGYQLQP 559
Query: 500 PKGYEAQTFNWENYLEKTKSKA 521
P ++ + +K K+K+
Sbjct: 560 PASQSSRENQSASSKQKKKAKS 581
>gi|71274154 Scm-like with four mbt domains 2 [Homo sapiens]
Length = 894
Score = 249 bits (635), Expect = 8e-66
Identities = 168/502 (33%), Positives = 246/502 (49%), Gaps = 49/502 (9%)
Query: 158 SQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVE 217
+ G G L + G GF+WG++L++ AAP + FKHV + Q + GMK+E
Sbjct: 25 ANGNGDL--DSEEGSSLEETGFNWGEYLEETGASAAPHTSFKHVEISIQ-SNFQPGMKLE 81
Query: 218 VLNSDAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINS 277
V N + YW+A++I T G +LLRY G+ D DFWC++ D+HP+GWC N+
Sbjct: 82 VANKNN---PDTYWVATIITTCGQLLLLRYCGYGEDRRADFWCDVVIADLHPVGWCTQNN 138
Query: 278 KILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYPFR---------QGMR 328
K+L+PP I K+TDW +L++ L GSRT P + ++ P R G
Sbjct: 139 KVLMPPDAIKEKYTDWTEFLIRDLTGSRTAPANL-------LEGPLRGKGPIDLITVGSL 191
Query: 329 LEVVDKSQVSRTRMAVVDTVIGGRLRLLY---EDGDSDDDFWCHMWSPLIHPVGWSR--- 382
+E+ D + + V +GGRLRL Y ED +S D W + PVGW +
Sbjct: 192 IELQDSQNPFQYWIVSVIENVGGRLRLRYVGLEDTESYDQ-WLFYLDYRLRPVGWCQENK 250
Query: 383 -RVGHGIKMSERRSDMAHHPTFRKIYCDAVPY-----LFKKVRAVYTEGGWFEEGMKLEA 436
R+ ++ + T K DA + +FK + + +F GMKLE
Sbjct: 251 YRMDPPSEIYPLKMASEWKCTLEKSLIDAAKFPLPMEVFKDHADLRSH--FFTVGMKLET 308
Query: 437 IDPLNLGNICVATVCKVLLDGYLMICVDG-GPSTDGLDWFCYHASSHAIFPATFCQKNDI 495
++ I A+V KV + + + +D P L C HA S I P +C KN +
Sbjct: 309 VNMCEPFYISPASVTKVFNNHFFQVTIDDLRPEPSKLSMLC-HADSLGILPVQWCLKNGV 367
Query: 496 ELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICV 555
LTPPKGY Q F+W +Y ++ ++ AP F + GF MKLEAV+ P +CV
Sbjct: 368 SLTPPKGYSGQDFDWADYHKQHGAQEAPPFCFRNTSFSRGFTKNMKLEAVNPRNPGELCV 427
Query: 556 ATVKRVVHRLLSIHFDGWDSEYDQ-WVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLK 614
A+V V RL+ +H +G + + VD ES DI+PVGWCE Y L P
Sbjct: 428 ASVVSVKGRLMWLHLEGLQTPVPEVIVDVESMDIFPVGWCEANSYPLTAP---------H 478
Query: 615 AKEATKKKKKQFGKKRKRIPPT 636
+ KK+K + K++PPT
Sbjct: 479 KTVSQKKRKIAVVQPEKQLPPT 500
>gi|53692193 Scm-like with four mbt domains 1 [Homo sapiens]
Length = 866
Score = 239 bits (611), Expect = 5e-63
Identities = 164/497 (32%), Positives = 252/497 (50%), Gaps = 39/497 (7%)
Query: 160 GTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEV- 218
G QL +G + + L W +L++ A P FKHV Q GMK+EV
Sbjct: 3 GEQQLDADAGSGMEEVELS--WEDYLEETGSTAVPYGSFKHVDTRLQ-NGFAPGMKLEVA 59
Query: 219 LNSDAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSK 278
+ +D YW+A+VI T +LLRY+G+ D DFWC++ D++PIGWC N K
Sbjct: 60 VRTDP----ETYWVATVITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKK 115
Query: 279 ILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYP---FRQGMRLEVVDKS 335
L P I K +DW +L + L+G+ + PV ++ + + + P G RLE
Sbjct: 116 TLEAPEGIRDKVSDWDEFLRQTLIGACSPPVPL-LEGLRNGRNPLDLIAPGSRLECQAFQ 174
Query: 336 QVSRTRMAVVDTVIGGRLRLLYEDGDSDDDF--WCHMWSPLIHPVGWSRRVGHGIKMSER 393
T + V IGGRL+L YE +S D++ W + P +H VGW+ + G+ ++
Sbjct: 175 DSLSTWIVTVVENIGGRLKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSA 234
Query: 394 RSDMAHHPTFRKIYC-------DAVP-YLF--KKVRAVYTEGGWFEEGMKLEAIDPLNLG 443
+ + +++I + +P YLF K+V ++T F MKLEA+DP +
Sbjct: 235 IRHLKNEAEWQEILAKVKEEEEEPLPSYLFKDKQVIGIHT----FSVNMKLEAVDPWSPF 290
Query: 444 NICVATVCKVLLDGYLMICVDG-GPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKG 502
I ATV KV + Y ++ +D P F HA S IFP + KN + ++PP G
Sbjct: 291 GISPATVVKVFDEKYFLVEMDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPG 350
Query: 503 YEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVV 562
Y +Q F+W +YL++ ++AAP R F H FK MKLEAV+ + P +CVAT+ V
Sbjct: 351 YPSQDFDWADYLKQCGAEAAPQRCFPPLISEHEFKENMKLEAVNPILPEEVCVATITAVR 410
Query: 563 HRLLSIHFDGWDSEYDQW-VDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKK 621
L + +G + V ES DI+P+GWCE G+ L +TP +A+ K+
Sbjct: 411 GSYLWLQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPL--------STPRRAR-VYKQ 461
Query: 622 KKKQFGKKRKRIPPTKT 638
+K + K++P ++T
Sbjct: 462 RKIAVVQPEKQVPSSRT 478
>gi|53692191 Scm-like with four mbt domains 1 [Homo sapiens]
Length = 866
Score = 239 bits (611), Expect = 5e-63
Identities = 164/497 (32%), Positives = 252/497 (50%), Gaps = 39/497 (7%)
Query: 160 GTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEV- 218
G QL +G + + L W +L++ A P FKHV Q GMK+EV
Sbjct: 3 GEQQLDADAGSGMEEVELS--WEDYLEETGSTAVPYGSFKHVDTRLQ-NGFAPGMKLEVA 59
Query: 219 LNSDAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSK 278
+ +D YW+A+VI T +LLRY+G+ D DFWC++ D++PIGWC N K
Sbjct: 60 VRTDP----ETYWVATVITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKK 115
Query: 279 ILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYP---FRQGMRLEVVDKS 335
L P I K +DW +L + L+G+ + PV ++ + + + P G RLE
Sbjct: 116 TLEAPEGIRDKVSDWDEFLRQTLIGACSPPVPL-LEGLRNGRNPLDLIAPGSRLECQAFQ 174
Query: 336 QVSRTRMAVVDTVIGGRLRLLYEDGDSDDDF--WCHMWSPLIHPVGWSRRVGHGIKMSER 393
T + V IGGRL+L YE +S D++ W + P +H VGW+ + G+ ++
Sbjct: 175 DSLSTWIVTVVENIGGRLKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSA 234
Query: 394 RSDMAHHPTFRKIYC-------DAVP-YLF--KKVRAVYTEGGWFEEGMKLEAIDPLNLG 443
+ + +++I + +P YLF K+V ++T F MKLEA+DP +
Sbjct: 235 IRHLKNEAEWQEILAKVKEEEEEPLPSYLFKDKQVIGIHT----FSVNMKLEAVDPWSPF 290
Query: 444 NICVATVCKVLLDGYLMICVDG-GPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKG 502
I ATV KV + Y ++ +D P F HA S IFP + KN + ++PP G
Sbjct: 291 GISPATVVKVFDEKYFLVEMDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPG 350
Query: 503 YEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVV 562
Y +Q F+W +YL++ ++AAP R F H FK MKLEAV+ + P +CVAT+ V
Sbjct: 351 YPSQDFDWADYLKQCGAEAAPQRCFPPLISEHEFKENMKLEAVNPILPEEVCVATITAVR 410
Query: 563 HRLLSIHFDGWDSEYDQW-VDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKK 621
L + +G + V ES DI+P+GWCE G+ L +TP +A+ K+
Sbjct: 411 GSYLWLQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPL--------STPRRAR-VYKQ 461
Query: 622 KKKQFGKKRKRIPPTKT 638
+K + K++P ++T
Sbjct: 462 RKIAVVQPEKQVPSSRT 478
>gi|53692195 Scm-like with four mbt domains 1 [Homo sapiens]
Length = 866
Score = 239 bits (611), Expect = 5e-63
Identities = 164/497 (32%), Positives = 252/497 (50%), Gaps = 39/497 (7%)
Query: 160 GTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEV- 218
G QL +G + + L W +L++ A P FKHV Q GMK+EV
Sbjct: 3 GEQQLDADAGSGMEEVELS--WEDYLEETGSTAVPYGSFKHVDTRLQ-NGFAPGMKLEVA 59
Query: 219 LNSDAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSK 278
+ +D YW+A+VI T +LLRY+G+ D DFWC++ D++PIGWC N K
Sbjct: 60 VRTDP----ETYWVATVITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKK 115
Query: 279 ILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYP---FRQGMRLEVVDKS 335
L P I K +DW +L + L+G+ + PV ++ + + + P G RLE
Sbjct: 116 TLEAPEGIRDKVSDWDEFLRQTLIGACSPPVPL-LEGLRNGRNPLDLIAPGSRLECQAFQ 174
Query: 336 QVSRTRMAVVDTVIGGRLRLLYEDGDSDDDF--WCHMWSPLIHPVGWSRRVGHGIKMSER 393
T + V IGGRL+L YE +S D++ W + P +H VGW+ + G+ ++
Sbjct: 175 DSLSTWIVTVVENIGGRLKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSA 234
Query: 394 RSDMAHHPTFRKIYC-------DAVP-YLF--KKVRAVYTEGGWFEEGMKLEAIDPLNLG 443
+ + +++I + +P YLF K+V ++T F MKLEA+DP +
Sbjct: 235 IRHLKNEAEWQEILAKVKEEEEEPLPSYLFKDKQVIGIHT----FSVNMKLEAVDPWSPF 290
Query: 444 NICVATVCKVLLDGYLMICVDG-GPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKG 502
I ATV KV + Y ++ +D P F HA S IFP + KN + ++PP G
Sbjct: 291 GISPATVVKVFDEKYFLVEMDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPG 350
Query: 503 YEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVV 562
Y +Q F+W +YL++ ++AAP R F H FK MKLEAV+ + P +CVAT+ V
Sbjct: 351 YPSQDFDWADYLKQCGAEAAPQRCFPPLISEHEFKENMKLEAVNPILPEEVCVATITAVR 410
Query: 563 HRLLSIHFDGWDSEYDQW-VDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKK 621
L + +G + V ES DI+P+GWCE G+ L +TP +A+ K+
Sbjct: 411 GSYLWLQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPL--------STPRRAR-VYKQ 461
Query: 622 KKKQFGKKRKRIPPTKT 638
+K + K++P ++T
Sbjct: 462 RKIAVVQPEKQVPSSRT 478
>gi|117938328 l(3)mbt-like isoform I [Homo sapiens]
Length = 772
Score = 192 bits (487), Expect = 1e-48
Identities = 121/324 (37%), Positives = 170/324 (52%), Gaps = 11/324 (3%)
Query: 293 WKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGR 352
W+ YL ++ + + + + V K F+ GM+LE +D S + V V G R
Sbjct: 208 WESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYFILTVAEVCGYR 267
Query: 353 LRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDA 410
LRL ++ DFW + SP IHP GW + GH ++ + + + + R A
Sbjct: 268 LRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTRAQA 327
Query: 411 VP-YLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPST 469
P +LF G F+ GMKLEA+D +N +CVA+V V+ D ++ D T
Sbjct: 328 APKHLFVSQSHSPPPLG-FQVGMKLEAVDRMNPSLVCVASVTDVV-DSRFLVHFDNWDDT 385
Query: 470 DGLDWFCYHASSHAIFPATFCQKNDIELTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFN 528
D++C SS I P +CQK LTPP+ Y + F WE YLE+T + A P+ F
Sbjct: 386 --YDYWC-DPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFK 442
Query: 529 MDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDI 588
+ P H F V MKLEAVD P LI VA+V+ V + IHFDGW YD W+D + PDI
Sbjct: 443 VR-PPHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDI 501
Query: 589 YPVGWCELTGYQLQPPVA-AEPAT 611
+P GWC TG+ LQPP+ EP++
Sbjct: 502 HPAGWCSKTGHPLQPPLGPREPSS 525
Score = 130 bits (326), Expect = 5e-30
Identities = 104/331 (31%), Positives = 153/331 (46%), Gaps = 24/331 (7%)
Query: 179 FDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMK-GMKVEVLNSDAVLPSRVYWIASVIQ 237
+ W +L++ APVS F+ ++ K GMK+E + D PS +Y+I +V +
Sbjct: 206 WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGI--DPQHPS-MYFILTVAE 262
Query: 238 TAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYL 297
GYR+ L ++G+ HDFW N + D+HP GW L PP+ + W YL
Sbjct: 263 VCGYRLRLHFDGYSE--CHDFWVNANSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYL 320
Query: 298 MKRLVGSRTLPVDFHIKMVESMKYP---FRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLR 354
+R H+ + +S P F+ GM+LE VD+ S +A V V+ R
Sbjct: 321 R----STRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVASVTDVVDSRFL 376
Query: 355 LLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSD---MAHHPTFRKIYCDAV 411
+ +++ D D+WC SP IHPVGW ++ G + + D + AV
Sbjct: 377 VHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNFCWEKYLEETGASAV 436
Query: 412 PYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDG 471
P KVR ++ F MKLEA+D N I VA+V + + D + I DG + G
Sbjct: 437 PTWAFKVRPPHS----FLVNMKLEAVDRRNPALIRVASV-EDVEDHRIKIHFDGW--SHG 489
Query: 472 LDWFCYHASSHAIFPATFCQKNDIELTPPKG 502
D F A I PA +C K L PP G
Sbjct: 490 YD-FWIDADHPDIHPAGWCSKTGHPLQPPLG 519
Score = 98.2 bits (243), Expect = 2e-20
Identities = 47/110 (42%), Positives = 67/110 (60%), Gaps = 4/110 (3%)
Query: 499 PPKGYEAQTFNWENYLEKTKSKAAPSRLFN----MDCPNHGFKVGMKLEAVDLMEPRLIC 554
P G + + ++WE+YLE+ K+ AP LF + +GFK+GMKLE +D P +
Sbjct: 197 PATGEKKECWSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYF 256
Query: 555 VATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPP 604
+ TV V L +HFDG+ +D WV+ SPDI+P GW E TG++LQPP
Sbjct: 257 ILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQPP 306
>gi|117938330 l(3)mbt-like isoform II [Homo sapiens]
Length = 738
Score = 192 bits (487), Expect = 1e-48
Identities = 121/324 (37%), Positives = 170/324 (52%), Gaps = 11/324 (3%)
Query: 293 WKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGR 352
W+ YL ++ + + + + V K F+ GM+LE +D S + V V G R
Sbjct: 208 WESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYFILTVAEVCGYR 267
Query: 353 LRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDA 410
LRL ++ DFW + SP IHP GW + GH ++ + + + + R A
Sbjct: 268 LRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTRAQA 327
Query: 411 VP-YLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPST 469
P +LF G F+ GMKLEA+D +N +CVA+V V+ D ++ D T
Sbjct: 328 APKHLFVSQSHSPPPLG-FQVGMKLEAVDRMNPSLVCVASVTDVV-DSRFLVHFDNWDDT 385
Query: 470 DGLDWFCYHASSHAIFPATFCQKNDIELTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFN 528
D++C SS I P +CQK LTPP+ Y + F WE YLE+T + A P+ F
Sbjct: 386 --YDYWC-DPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFK 442
Query: 529 MDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDI 588
+ P H F V MKLEAVD P LI VA+V+ V + IHFDGW YD W+D + PDI
Sbjct: 443 VR-PPHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDI 501
Query: 589 YPVGWCELTGYQLQPPVA-AEPAT 611
+P GWC TG+ LQPP+ EP++
Sbjct: 502 HPAGWCSKTGHPLQPPLGPREPSS 525
Score = 130 bits (326), Expect = 5e-30
Identities = 104/331 (31%), Positives = 153/331 (46%), Gaps = 24/331 (7%)
Query: 179 FDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMK-GMKVEVLNSDAVLPSRVYWIASVIQ 237
+ W +L++ APVS F+ ++ K GMK+E + D PS +Y+I +V +
Sbjct: 206 WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGI--DPQHPS-MYFILTVAE 262
Query: 238 TAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYL 297
GYR+ L ++G+ HDFW N + D+HP GW L PP+ + W YL
Sbjct: 263 VCGYRLRLHFDGYSE--CHDFWVNANSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYL 320
Query: 298 MKRLVGSRTLPVDFHIKMVESMKYP---FRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLR 354
+R H+ + +S P F+ GM+LE VD+ S +A V V+ R
Sbjct: 321 R----STRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVASVTDVVDSRFL 376
Query: 355 LLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSD---MAHHPTFRKIYCDAV 411
+ +++ D D+WC SP IHPVGW ++ G + + D + AV
Sbjct: 377 VHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNFCWEKYLEETGASAV 436
Query: 412 PYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDG 471
P KVR ++ F MKLEA+D N I VA+V + + D + I DG + G
Sbjct: 437 PTWAFKVRPPHS----FLVNMKLEAVDRRNPALIRVASV-EDVEDHRIKIHFDGW--SHG 489
Query: 472 LDWFCYHASSHAIFPATFCQKNDIELTPPKG 502
D F A I PA +C K L PP G
Sbjct: 490 YD-FWIDADHPDIHPAGWCSKTGHPLQPPLG 519
Score = 98.2 bits (243), Expect = 2e-20
Identities = 47/110 (42%), Positives = 67/110 (60%), Gaps = 4/110 (3%)
Query: 499 PPKGYEAQTFNWENYLEKTKSKAAPSRLFN----MDCPNHGFKVGMKLEAVDLMEPRLIC 554
P G + + ++WE+YLE+ K+ AP LF + +GFK+GMKLE +D P +
Sbjct: 197 PATGEKKECWSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYF 256
Query: 555 VATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPP 604
+ TV V L +HFDG+ +D WV+ SPDI+P GW E TG++LQPP
Sbjct: 257 ILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQPP 306
>gi|158138528 l(3)mbt-like 4 [Homo sapiens]
Length = 623
Score = 187 bits (474), Expect = 4e-47
Identities = 116/317 (36%), Positives = 172/317 (54%), Gaps = 11/317 (3%)
Query: 293 WKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGR 352
W+ YL ++ + + + + + F+ GMRLE +D S + V V G R
Sbjct: 54 WEWYLKEQKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYR 113
Query: 353 LRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSER-RSDMAHHPTFRKIYC--- 408
LRL ++ S DFW + SP IHPVGW + H + + + R D + K C
Sbjct: 114 LRLHFDGYLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKA-CKLQ 172
Query: 409 DAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPS 468
+A LF+ F+ GMKLEA+D N +CVAT+ ++ D L++ D
Sbjct: 173 NAPKKLFRNRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDR-LLVHFDNWD- 230
Query: 469 TDGLDWFCYHASSHAIFPATFCQKNDIELTPPKGY-EAQTFNWENYLEKTKSKAAPSRLF 527
D D++C +S + P +CQ+N L P+GY + F+W YLE T++ A P+++F
Sbjct: 231 -DSYDYWC-DVNSPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVF 288
Query: 528 NMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPD 587
M P HGF MKLE VD PRLI VAT+ V + + +HFDGWD +YD WV+ +SPD
Sbjct: 289 KMRLP-HGFLPNMKLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPD 347
Query: 588 IYPVGWCELTGYQLQPP 604
I+P+GWC++TG+ L+ P
Sbjct: 348 IHPIGWCDVTGHPLEVP 364
Score = 110 bits (276), Expect = 3e-24
Identities = 79/279 (28%), Positives = 130/279 (46%), Gaps = 13/279 (4%)
Query: 179 FDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMK-GMKVEVLNSDAVLPSRVYWIASVIQ 237
+ W +LK+ AAPV F + + E+ + GM++E + D PS V+ + SV +
Sbjct: 52 WSWEWYLKEQKAVAAPVELFSKDQSFPEHENGFQIGMRLEGI--DPRHPS-VFCVLSVAE 108
Query: 238 TAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYL 297
GYR+ L ++G+ + +DFW N G+ D+HP+GWC L P+ W YL
Sbjct: 109 VCGYRLRLHFDGYLS--CYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYL 166
Query: 298 MKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLY 357
+ + + + M F+ GM+LE VD+ S +A + ++ RL + +
Sbjct: 167 KACKLQNAPKKLFRNRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHF 226
Query: 358 EDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSE---RRSDMAHHPTFRKIYCDAVPYL 414
++ D D+WC + SP + PVGW + G + + + + +AVP
Sbjct: 227 DNWDDSYDYWCDVNSPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAK 286
Query: 415 FKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKV 453
K+R + F MKLE +D N I VAT+ V
Sbjct: 287 VFKMRLPH----GFLPNMKLEVVDKRNPRLIRVATIVDV 321
Score = 95.9 bits (237), Expect = 1e-19
Identities = 48/109 (44%), Positives = 66/109 (60%), Gaps = 4/109 (3%)
Query: 500 PKGYEAQTFNWENYLEKTKSKAAPSRLFNMD--CPNH--GFKVGMKLEAVDLMEPRLICV 555
P ++WE YL++ K+ AAP LF+ D P H GF++GM+LE +D P + CV
Sbjct: 44 PSAAAQGAWSWEWYLKEQKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCV 103
Query: 556 ATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPP 604
+V V L +HFDG+ S YD W + SPDI+PVGWCE T ++L P
Sbjct: 104 LSVAEVCGYRLRLHFDGYLSCYDFWTNAGSPDIHPVGWCEKTKHELHIP 152
Score = 94.7 bits (234), Expect = 3e-19
Identities = 65/223 (29%), Positives = 111/223 (49%), Gaps = 16/223 (7%)
Query: 179 FDWGKFLKDHSYKAAPVSCFKH-VPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQ 237
F W +LK + AP F++ P ++ GMK+E + D PS V +A++
Sbjct: 160 FVWMDYLKACKLQNAPKKLFRNRSPNGPMSKEFQVGMKLEAV--DRKNPSLVC-VATIAD 216
Query: 238 TAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTI-HAKFTDWKGY 296
R+L+ ++ + D S+D+WC++ + V P+GWC N + L+ P+ + + W Y
Sbjct: 217 IVEDRLLVHFDNW--DDSYDYWCDVNSPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEY 274
Query: 297 LMKRLVGSRTLPVDFHIKMVESMKYP--FRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLR 354
L + +P V M+ P F M+LEVVDK R+A + V R++
Sbjct: 275 L--EATQTNAVPAK-----VFKMRLPHGFLPNMKLEVVDKRNPRLIRVATIVDVDDQRVK 327
Query: 355 LLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDM 397
+ ++ D D+W SP IHP+GW GH +++ +R +D+
Sbjct: 328 VHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPLEVPQRTNDL 370
>gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens]
Length = 755
Score = 182 bits (463), Expect = 7e-46
Identities = 113/305 (37%), Positives = 162/305 (53%), Gaps = 15/305 (4%)
Query: 320 KYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVG 379
K F+ GM+LE VD S + V V G R++L ++ DFW + + IHPVG
Sbjct: 236 KNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVG 295
Query: 380 WSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDAVPY-LFKKVRAVYTEGGWFEEGMKLEA 436
W + GH + + + + + A P LF+ G F GMKLEA
Sbjct: 296 WCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSG-FRVGMKLEA 354
Query: 437 IDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIE 496
+D N ICVATV ++D ++ D + D++C +S H I P +C+++
Sbjct: 355 VDKKNPSFICVATVTD-MVDNRFLVHFDNWD--ESYDYWCEASSPH-IHPVGWCKEHRRT 410
Query: 497 LTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICV 555
L P GY + F+W+ YLE+T S AP+R F + P HGF+ MKLE VD P I V
Sbjct: 411 LITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVK-PPHGFQKKMKLEVVDKRNPMFIRV 469
Query: 556 ATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKA 615
ATV + +HFDGW++ YD W+D +SPDI+PVGWC TG+ LQPP+ +PL+
Sbjct: 470 ATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPL-----SPLEL 524
Query: 616 KEATK 620
EA++
Sbjct: 525 MEASE 529
Score = 125 bits (314), Expect = 1e-28
Identities = 98/338 (28%), Positives = 151/338 (44%), Gaps = 46/338 (13%)
Query: 181 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMK-GMKVEVLNSDAVLPSRVYWIASVIQTA 239
W +L++ A P FK + ++ K GMK+E ++ + VY + +V +
Sbjct: 209 WASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEH---QSVYCVLTVAEVC 265
Query: 240 GYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYL-- 297
GYR+ L ++G+ + +DFW N +D+HP+GWC L PP+ + +W+ YL
Sbjct: 266 GYRIKLHFDGYSD--CYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKT 323
Query: 298 MKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLY 357
K ++L + +I ++ S FR GM+LE VDK S +A V ++ R + +
Sbjct: 324 CKAQAAPKSLFENQNITVIPS---GFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHF 380
Query: 358 EDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKI-------YCDA 410
++ D D+WC SP IHPVGW + E R + P + + Y +
Sbjct: 381 DNWDESYDYWCEASSPHIHPVGWCK---------EHRRTLITPPGYPNVKHFSWDKYLEE 431
Query: 411 VPYLFKKVRAVYTE-GGWFEEGMKLEAIDPLNLGNICVATVC-------KVLLDGYLMIC 462
L RA + F++ MKLE +D N I VATV KV DG+ C
Sbjct: 432 TNSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGW-NNC 490
Query: 463 VDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPP 500
D + A S I P +C K L PP
Sbjct: 491 YD----------YWIDADSPDIHPVGWCSKTGHPLQPP 518
Score = 102 bits (255), Expect = 9e-22
Identities = 59/150 (39%), Positives = 83/150 (55%), Gaps = 11/150 (7%)
Query: 499 PPKGYEAQTFNWENYLEKTKSKAAPSRLF----NMDCPNHGFKVGMKLEAVDLMEPRLIC 554
PPKG +A + W +YLE+ K+ A P++LF + +GFKVGMKLE VD + C
Sbjct: 200 PPKGKKA--WCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYC 257
Query: 555 VATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEP----- 609
V TV V + +HFDG+ YD WV+ ++ DI+PVGWCE TG++L PP +
Sbjct: 258 VLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNW 317
Query: 610 ATPLKAKEATKKKKKQFGKKRKRIPPTKTR 639
T LK +A K F + + P+ R
Sbjct: 318 QTYLKTCKAQAAPKSLFENQNITVIPSGFR 347
Score = 100 bits (249), Expect = 5e-21
Identities = 72/248 (29%), Positives = 117/248 (47%), Gaps = 23/248 (9%)
Query: 143 LHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVP 202
+H W K G LH P G F+W +LK +AAP S F++
Sbjct: 291 IHPVGWCEKTGHKLHP----------PKGYKEEE--FNWQTYLKTCKAQAAPKSLFENQN 338
Query: 203 LYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNL 262
+ GMK+E + D PS + +A+V R L+ ++ + D S+D+WC
Sbjct: 339 ITVIPSGFRVGMKLEAV--DKKNPSFI-CVATVTDMVDNRFLVHFDNW--DESYDYWCEA 393
Query: 263 GTVDVHPIGWCAINSKILV-PPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKY 321
+ +HP+GWC + + L+ PP + K W YL + + +LP V+ +
Sbjct: 394 SSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEE----TNSLPAPARAFKVKP-PH 448
Query: 322 PFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWS 381
F++ M+LEVVDK R+A V R+++ ++ ++ D+W SP IHPVGW
Sbjct: 449 GFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWC 508
Query: 382 RRVGHGIK 389
+ GH ++
Sbjct: 509 SKTGHPLQ 516
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/116 (32%), Positives = 60/116 (51%), Gaps = 10/116 (8%)
Query: 168 TPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPS 227
TP G V F W K+L++ + AP FK P + K MK+EV++ +
Sbjct: 413 TPPGYPN-VKHFSWDKYLEETNSLPAPARAFKVKPPH----GFQKKMKLEVVDKRNPMFI 467
Query: 228 RVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPP 283
RV A+V T +RV + ++G+ N +D+W + + D+HP+GWC+ L PP
Sbjct: 468 RV---ATVADTDDHRVKVHFDGWNN--CYDYWIDADSPDIHPVGWCSKTGHPLQPP 518
>gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens]
Length = 780
Score = 182 bits (463), Expect = 7e-46
Identities = 113/305 (37%), Positives = 162/305 (53%), Gaps = 15/305 (4%)
Query: 320 KYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVG 379
K F+ GM+LE VD S + V V G R++L ++ DFW + + IHPVG
Sbjct: 261 KNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVG 320
Query: 380 WSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDAVPY-LFKKVRAVYTEGGWFEEGMKLEA 436
W + GH + + + + + A P LF+ G F GMKLEA
Sbjct: 321 WCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSG-FRVGMKLEA 379
Query: 437 IDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIE 496
+D N ICVATV ++D ++ D + D++C +S H I P +C+++
Sbjct: 380 VDKKNPSFICVATVTD-MVDNRFLVHFDNWD--ESYDYWCEASSPH-IHPVGWCKEHRRT 435
Query: 497 LTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICV 555
L P GY + F+W+ YLE+T S AP+R F + P HGF+ MKLE VD P I V
Sbjct: 436 LITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVK-PPHGFQKKMKLEVVDKRNPMFIRV 494
Query: 556 ATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKA 615
ATV + +HFDGW++ YD W+D +SPDI+PVGWC TG+ LQPP+ +PL+
Sbjct: 495 ATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPL-----SPLEL 549
Query: 616 KEATK 620
EA++
Sbjct: 550 MEASE 554
Score = 125 bits (314), Expect = 1e-28
Identities = 98/338 (28%), Positives = 151/338 (44%), Gaps = 46/338 (13%)
Query: 181 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMK-GMKVEVLNSDAVLPSRVYWIASVIQTA 239
W +L++ A P FK + ++ K GMK+E ++ + VY + +V +
Sbjct: 234 WASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEH---QSVYCVLTVAEVC 290
Query: 240 GYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYL-- 297
GYR+ L ++G+ + +DFW N +D+HP+GWC L PP+ + +W+ YL
Sbjct: 291 GYRIKLHFDGYSD--CYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKT 348
Query: 298 MKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLY 357
K ++L + +I ++ S FR GM+LE VDK S +A V ++ R + +
Sbjct: 349 CKAQAAPKSLFENQNITVIPS---GFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHF 405
Query: 358 EDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKI-------YCDA 410
++ D D+WC SP IHPVGW + E R + P + + Y +
Sbjct: 406 DNWDESYDYWCEASSPHIHPVGWCK---------EHRRTLITPPGYPNVKHFSWDKYLEE 456
Query: 411 VPYLFKKVRAVYTE-GGWFEEGMKLEAIDPLNLGNICVATVC-------KVLLDGYLMIC 462
L RA + F++ MKLE +D N I VATV KV DG+ C
Sbjct: 457 TNSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGW-NNC 515
Query: 463 VDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPP 500
D + A S I P +C K L PP
Sbjct: 516 YD----------YWIDADSPDIHPVGWCSKTGHPLQPP 543
Score = 102 bits (255), Expect = 9e-22
Identities = 59/150 (39%), Positives = 83/150 (55%), Gaps = 11/150 (7%)
Query: 499 PPKGYEAQTFNWENYLEKTKSKAAPSRLF----NMDCPNHGFKVGMKLEAVDLMEPRLIC 554
PPKG +A + W +YLE+ K+ A P++LF + +GFKVGMKLE VD + C
Sbjct: 225 PPKGKKA--WCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYC 282
Query: 555 VATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEP----- 609
V TV V + +HFDG+ YD WV+ ++ DI+PVGWCE TG++L PP +
Sbjct: 283 VLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNW 342
Query: 610 ATPLKAKEATKKKKKQFGKKRKRIPPTKTR 639
T LK +A K F + + P+ R
Sbjct: 343 QTYLKTCKAQAAPKSLFENQNITVIPSGFR 372
Score = 100 bits (249), Expect = 5e-21
Identities = 72/248 (29%), Positives = 117/248 (47%), Gaps = 23/248 (9%)
Query: 143 LHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVP 202
+H W K G LH P G F+W +LK +AAP S F++
Sbjct: 316 IHPVGWCEKTGHKLHP----------PKGYKEEE--FNWQTYLKTCKAQAAPKSLFENQN 363
Query: 203 LYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNL 262
+ GMK+E + D PS + +A+V R L+ ++ + D S+D+WC
Sbjct: 364 ITVIPSGFRVGMKLEAV--DKKNPSFI-CVATVTDMVDNRFLVHFDNW--DESYDYWCEA 418
Query: 263 GTVDVHPIGWCAINSKILV-PPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKY 321
+ +HP+GWC + + L+ PP + K W YL + + +LP V+ +
Sbjct: 419 SSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEE----TNSLPAPARAFKVKP-PH 473
Query: 322 PFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWS 381
F++ M+LEVVDK R+A V R+++ ++ ++ D+W SP IHPVGW
Sbjct: 474 GFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWC 533
Query: 382 RRVGHGIK 389
+ GH ++
Sbjct: 534 SKTGHPLQ 541
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/116 (32%), Positives = 60/116 (51%), Gaps = 10/116 (8%)
Query: 168 TPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPS 227
TP G V F W K+L++ + AP FK P + K MK+EV++ +
Sbjct: 438 TPPGYPN-VKHFSWDKYLEETNSLPAPARAFKVKPPH----GFQKKMKLEVVDKRNPMFI 492
Query: 228 RVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPP 283
RV A+V T +RV + ++G+ N +D+W + + D+HP+GWC+ L PP
Sbjct: 493 RV---ATVADTDDHRVKVHFDGWNN--CYDYWIDADSPDIHPVGWCSKTGHPLQPP 543
>gi|5174669 sex comb on midleg-like 2 [Homo sapiens]
Length = 700
Score = 130 bits (327), Expect = 4e-30
Identities = 80/194 (41%), Positives = 104/194 (53%), Gaps = 9/194 (4%)
Query: 428 FEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPA 487
F+ GMKLEA DP N ++C+ATV + L + +DG +D + F S I P
Sbjct: 63 FKVGMKLEARDPRNATSVCIATVIGIT-GARLRLRLDG---SDNRNDFWRLVDSPDIQPV 118
Query: 488 TFCQKNDIELTPPKGYEAQTFNWENYLEKTK--SKAAPSRLFNMDCPN---HGFKVGMKL 542
C+K L PP GY+ T +W +L KT S+ A + LF + P + FKVGMKL
Sbjct: 119 GTCEKEGDLLQPPLGYQMNTSSWPMFLLKTLNGSEMASATLFKKEPPKPPLNNFKVGMKL 178
Query: 543 EAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQ 602
EA+D P LIC AT+ V + I FDGW +D W +S DI+P GWC LTG LQ
Sbjct: 179 EAIDKKNPYLICPATIGDVKGDEVHITFDGWSGAFDYWCKYDSRDIFPAGWCRLTGDVLQ 238
Query: 603 PPVAAEPATPLKAK 616
PP + P AK
Sbjct: 239 PPGTSVPIVKNIAK 252
Score = 91.3 bits (225), Expect = 3e-18
Identities = 65/213 (30%), Positives = 96/213 (45%), Gaps = 17/213 (7%)
Query: 179 FDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVL---NSDAVLPSRVYWIASV 235
F W ++LK+ +AP CF+ + D GMK+E N+ +V IA+V
Sbjct: 33 FHWEEYLKETGSISAPSECFRQSQI-PPVNDFKVGMKLEARDPRNATSVC------IATV 85
Query: 236 IQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKG 295
I G R+ LR +G +N +DFW + + D+ P+G C +L PP + W
Sbjct: 86 IGITGARLRLRLDGSDN--RNDFWRLVDSPDIQPVGTCEKEGDLLQPPLGYQMNTSSWPM 143
Query: 296 YLMKRLVGSRTLPVDFHIKMVESMKYP---FRQGMRLEVVDKSQVSRTRMAVVDTVIGGR 352
+L+K L GS K E K P F+ GM+LE +DK A + V G
Sbjct: 144 FLLKTLNGSEMASATLFKK--EPPKPPLNNFKVGMKLEAIDKKNPYLICPATIGDVKGDE 201
Query: 353 LRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVG 385
+ + ++ D+WC S I P GW R G
Sbjct: 202 VHITFDGWSGAFDYWCKYDSRDIFPAGWCRLTG 234
Score = 87.0 bits (214), Expect = 5e-17
Identities = 57/156 (36%), Positives = 75/156 (48%), Gaps = 11/156 (7%)
Query: 491 QKNDIELTPPKG---YEAQTFNWENYLEKTKSKAAPSRLFNMDC--PNHGFKVGMKLEAV 545
+K + E TP + F+WE YL++T S +APS F P + FKVGMKLEA
Sbjct: 13 KKENQEKTPQSSTSSVQRDDFHWEEYLKETGSISAPSECFRQSQIPPVNDFKVGMKLEAR 72
Query: 546 DLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPV 605
D +C+ATV + L + DG D+ D W +SPDI PVG CE G LQPP+
Sbjct: 73 DPRNATSVCIATVIGITGARLRLRLDGSDNRNDFWRLVDSPDIQPVGTCEKEGDLLQPPL 132
Query: 606 AAE------PATPLKAKEATKKKKKQFGKKRKRIPP 635
+ P LK ++ KK PP
Sbjct: 133 GYQMNTSSWPMFLLKTLNGSEMASATLFKKEPPKPP 168
Score = 67.0 bits (162), Expect = 6e-11
Identities = 69/214 (32%), Positives = 95/214 (44%), Gaps = 14/214 (6%)
Query: 293 WKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGR 352
W+ YL + GS + P + + F+ GM+LE D + +A V + G R
Sbjct: 35 WEEYLKE--TGSISAPSECFRQSQIPPVNDFKVGMKLEARDPRNATSVCIATVIGITGAR 92
Query: 353 LRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGH------GIKMSERRSDMAHHPTFRKI 406
LRL + D+ +DFW + SP I PVG + G G +M+ M T
Sbjct: 93 LRLRLDGSDNRNDFWRLVDSPDIQPVGTCEKEGDLLQPPLGYQMNTSSWPMFLLKTLNGS 152
Query: 407 YCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGG 466
A LFKK F+ GMKLEAID N IC AT+ V D + I DG
Sbjct: 153 EM-ASATLFKKEPPKPPLNN-FKVGMKLEAIDKKNPYLICPATIGDVKGD-EVHITFDGW 209
Query: 467 PSTDGLDWFCYHASSHAIFPATFCQKNDIELTPP 500
+ D++C + S IFPA +C+ L PP
Sbjct: 210 --SGAFDYWCKY-DSRDIFPAGWCRLTGDVLQPP 240
Score = 44.7 bits (104), Expect = 3e-04
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 11/109 (10%)
Query: 181 WGKFLKD--HSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWI--ASVI 236
W FL + + A + FK P + GMK+E ++ Y I A++
Sbjct: 141 WPMFLLKTLNGSEMASATLFKKEPPKPPLNNFKVGMKLEAIDK-----KNPYLICPATIG 195
Query: 237 QTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRT 285
G V + ++G+ + D+WC + D+ P GWC + +L PP T
Sbjct: 196 DVKGDEVHITFDGWSG--AFDYWCKYDSRDIFPAGWCRLTGDVLQPPGT 242
>gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens]
Length = 660
Score = 129 bits (325), Expect = 7e-30
Identities = 100/292 (34%), Positives = 137/292 (46%), Gaps = 33/292 (11%)
Query: 428 FEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPA 487
F+ MKLEA DP N + C+ATV L L + +DG +D + F S I P
Sbjct: 58 FKISMKLEAQDPRNTTSTCIATVVG-LTGARLRLRLDG---SDNKNDFWRLVDSAEIQPI 113
Query: 488 TFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKA--APSRLFNMD--CPNHGF-KVGMKL 542
C+KN L PP G+ +W +L KT + A AP R+F+ + P+H F K+GMKL
Sbjct: 114 GNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKL 173
Query: 543 EAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQ 602
EAVD P IC AT+ V + + FDGW +D W +S DI+PVGWC LTG LQ
Sbjct: 174 EAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQ 233
Query: 603 PP--VAAEPATPLKAKEATKKKK------------------KQFGKKRKRIPPTK-TRPL 641
PP P P A + +K ++ GKKR R P T + P+
Sbjct: 234 PPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPI 293
Query: 642 RQGSK--KPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPE 691
SK +PL +G K S+ P ++ PD ++ P+
Sbjct: 294 SAPSKTAEPLKFPKKRGP-KPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQ 344
Score = 98.2 bits (243), Expect = 2e-20
Identities = 66/226 (29%), Positives = 105/226 (46%), Gaps = 17/226 (7%)
Query: 167 GTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFK--HVPLYDQWEDVMKGMKVEVLNSDAV 224
G+P G F W K+LK+ APV CFK + P ++++ MK + N+ +
Sbjct: 22 GSPLGH------FTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTST 75
Query: 225 LPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPR 284
IA+V+ G R+ LR +G +N +DFW + + ++ PIG C N +L PP
Sbjct: 76 C------IATVVGLTGARLRLRLDGSDN--KNDFWRLVDSAEIQPIGNCEKNGGMLQPPL 127
Query: 285 TIHAKFTDWKGYLMKRLVGSRTLPVD-FHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMA 343
+ W +L+K L G+ P+ FH + F+ GM+LE VD+ A
Sbjct: 128 GFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPA 187
Query: 344 VVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIK 389
+ V G + + ++ D+WC S I PVGW G ++
Sbjct: 188 TIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQ 233
Score = 72.8 bits (177), Expect = 1e-12
Identities = 39/100 (39%), Positives = 54/100 (54%), Gaps = 2/100 (2%)
Query: 508 FNWENYLEKTKSKAAPSRLFNMDC--PNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRL 565
F W+ YL++T S AP F P++ FK+ MKLEA D C+ATV +
Sbjct: 28 FTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGAR 87
Query: 566 LSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPV 605
L + DG D++ D W +S +I P+G CE G LQPP+
Sbjct: 88 LRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPL 127
Score = 60.8 bits (146), Expect = 4e-09
Identities = 54/192 (28%), Positives = 81/192 (42%), Gaps = 28/192 (14%)
Query: 323 FRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSR 382
F+ M+LE D + T +A V + G RLRL + D+ +DFW + S I P+G
Sbjct: 58 FKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIG--- 114
Query: 383 RVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKK---------VRAVYTEG-----GWF 428
E+ M P ++ + P K +R + E +F
Sbjct: 115 -------NCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFF 167
Query: 429 EEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPAT 488
+ GMKLEA+D N IC AT+ +V +++ DG D++C S IFP
Sbjct: 168 KMGMKLEAVDRKNPHFICPATIGEV-RGSEVLVTFDGW--RGAFDYWC-RFDSRDIFPVG 223
Query: 489 FCQKNDIELTPP 500
+C L PP
Sbjct: 224 WCSLTGDNLQPP 235
Score = 48.9 bits (115), Expect = 2e-05
Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 13/110 (11%)
Query: 181 WGKFLKD--HSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVL---NSDAVLPSRVYWIASV 235
W FL + + AP+ F P GMK+E + N + P A++
Sbjct: 136 WPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICP------ATI 189
Query: 236 IQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRT 285
+ G VL+ ++G+ + D+WC + D+ P+GWC++ L PP T
Sbjct: 190 GEVRGSEVLVTFDGWRG--AFDYWCRFDSRDIFPVGWCSLTGDNLQPPGT 237
>gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens]
Length = 591
Score = 129 bits (325), Expect = 7e-30
Identities = 100/292 (34%), Positives = 137/292 (46%), Gaps = 33/292 (11%)
Query: 428 FEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPA 487
F+ MKLEA DP N + C+ATV L L + +DG +D + F S I P
Sbjct: 11 FKISMKLEAQDPRNTTSTCIATVVG-LTGARLRLRLDG---SDNKNDFWRLVDSAEIQPI 66
Query: 488 TFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKA--APSRLFNMD--CPNHGF-KVGMKL 542
C+KN L PP G+ +W +L KT + A AP R+F+ + P+H F K+GMKL
Sbjct: 67 GNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKL 126
Query: 543 EAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQ 602
EAVD P IC AT+ V + + FDGW +D W +S DI+PVGWC LTG LQ
Sbjct: 127 EAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQ 186
Query: 603 PP--VAAEPATPLKAKEATKKKK------------------KQFGKKRKRIPPTK-TRPL 641
PP P P A + +K ++ GKKR R P T + P+
Sbjct: 187 PPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPI 246
Query: 642 RQGSK--KPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPE 691
SK +PL +G K S+ P ++ PD ++ P+
Sbjct: 247 SAPSKTAEPLKFPKKRGP-KPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQ 297
Score = 82.4 bits (202), Expect = 1e-15
Identities = 48/159 (30%), Positives = 76/159 (47%), Gaps = 3/159 (1%)
Query: 232 IASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFT 291
IA+V+ G R+ LR +G +N +DFW + + ++ PIG C N +L PP +
Sbjct: 30 IATVVGLTGARLRLRLDGSDN--KNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNAS 87
Query: 292 DWKGYLMKRLVGSRTLPVD-FHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIG 350
W +L+K L G+ P+ FH + F+ GM+LE VD+ A + V G
Sbjct: 88 SWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRG 147
Query: 351 GRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIK 389
+ + ++ D+WC S I PVGW G ++
Sbjct: 148 SEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQ 186
Score = 60.8 bits (146), Expect = 4e-09
Identities = 54/192 (28%), Positives = 81/192 (42%), Gaps = 28/192 (14%)
Query: 323 FRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSR 382
F+ M+LE D + T +A V + G RLRL + D+ +DFW + S I P+G
Sbjct: 11 FKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIG--- 67
Query: 383 RVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKK---------VRAVYTE-----GGWF 428
E+ M P ++ + P K +R + E +F
Sbjct: 68 -------NCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFF 120
Query: 429 EEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPAT 488
+ GMKLEA+D N IC AT+ +V +++ DG D++C S IFP
Sbjct: 121 KMGMKLEAVDRKNPHFICPATIGEV-RGSEVLVTFDGW--RGAFDYWC-RFDSRDIFPVG 176
Query: 489 FCQKNDIELTPP 500
+C L PP
Sbjct: 177 WCSLTGDNLQPP 188
Score = 59.7 bits (143), Expect = 9e-09
Identities = 30/74 (40%), Positives = 42/74 (56%)
Query: 532 PNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPV 591
P++ FK+ MKLEA D C+ATV + L + DG D++ D W +S +I P+
Sbjct: 7 PSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPI 66
Query: 592 GWCELTGYQLQPPV 605
G CE G LQPP+
Sbjct: 67 GNCEKNGGMLQPPL 80
Score = 48.9 bits (115), Expect = 2e-05
Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 13/110 (11%)
Query: 181 WGKFLKD--HSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVL---NSDAVLPSRVYWIASV 235
W FL + + AP+ F P GMK+E + N + P A++
Sbjct: 89 WPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICP------ATI 142
Query: 236 IQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRT 285
+ G VL+ ++G+ + D+WC + D+ P+GWC++ L PP T
Sbjct: 143 GEVRGSEVLVTFDGWRG--AFDYWCRFDSRDIFPVGWCSLTGDNLQPPGT 190
>gi|148612879 polyhomeotic like 3 [Homo sapiens]
Length = 995
Score = 45.1 bits (105), Expect = 2e-04
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 16/92 (17%)
Query: 44 SSSYLEESSEAENEDREAGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFF 103
++ + + SS+ E ED A E +L+ SE CE CG +G F
Sbjct: 766 NTKHADNSSDTEMEDMIAEE---------------TLEEMDSELLKCEFCGKMGYANEFL 810
Query: 104 SKTKRFCSVSCSRSYSSNSKKASILARLQGKP 135
++KRFC++SC++ Y+ + K L+R KP
Sbjct: 811 -RSKRFCTMSCAKRYNVSCSKKFALSRWNRKP 841
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 44.7 bits (104), Expect = 3e-04
Identities = 48/179 (26%), Positives = 79/179 (44%), Gaps = 13/179 (7%)
Query: 2 EKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSV-GSESSSYLEESSEAENEDRE 60
+K R + +SE EEEE+ + E S NSSV G++ S ++E ++AE E +
Sbjct: 74 KKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETE--K 131
Query: 61 AGELPTSPLH---------LLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTK-RFC 110
AG+ S H LLS +PR + + G+ AF + K
Sbjct: 132 AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 111 SVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTP 169
S + S S ++ +S ++GKP K A+V + + + A + G++ D TP
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTP 250
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 44.7 bits (104), Expect = 3e-04
Identities = 48/179 (26%), Positives = 79/179 (44%), Gaps = 13/179 (7%)
Query: 2 EKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSV-GSESSSYLEESSEAENEDRE 60
+K R + +SE EEEE+ + E S NSSV G++ S ++E ++AE E +
Sbjct: 74 KKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETE--K 131
Query: 61 AGELPTSPLH---------LLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTK-RFC 110
AG+ S H LLS +PR + + G+ AF + K
Sbjct: 132 AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 111 SVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTP 169
S + S S ++ +S ++GKP K A+V + + + A + G++ D TP
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTP 250
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 44.7 bits (104), Expect = 3e-04
Identities = 48/179 (26%), Positives = 79/179 (44%), Gaps = 13/179 (7%)
Query: 2 EKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSV-GSESSSYLEESSEAENEDRE 60
+K R + +SE EEEE+ + E S NSSV G++ S ++E ++AE E +
Sbjct: 74 KKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETE--K 131
Query: 61 AGELPTSPLH---------LLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTK-RFC 110
AG+ S H LLS +PR + + G+ AF + K
Sbjct: 132 AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 111 SVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTP 169
S + S S ++ +S ++GKP K A+V + + + A + G++ D TP
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTP 250
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 44.7 bits (104), Expect = 3e-04
Identities = 48/179 (26%), Positives = 79/179 (44%), Gaps = 13/179 (7%)
Query: 2 EKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSV-GSESSSYLEESSEAENEDRE 60
+K R + +SE EEEE+ + E S NSSV G++ S ++E ++AE E +
Sbjct: 74 KKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETE--K 131
Query: 61 AGELPTSPLH---------LLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTK-RFC 110
AG+ S H LLS +PR + + G+ AF + K
Sbjct: 132 AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 111 SVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTP 169
S + S S ++ +S ++GKP K A+V + + + A + G++ D TP
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTP 250
>gi|4504993 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 35.8 bits (81), Expect = 0.14
Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 10/88 (11%)
Query: 11 PSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDREAGELPTSPLH 70
P ++P EE+E+D + GG Y + +S +E+ + E+ D+ AG P + ++
Sbjct: 983 PQAKPEEEQENDPV---GG----AGYKPQMHLPINSTVEDIAAEEDLDKTAGYRPQANVN 1035
Query: 71 ---LLSPGTPRSLDGSGSEPAVCEMCGI 95
L+SP +PRS+D + + C I
Sbjct: 1036 TWNLVSPDSPRSIDSNSEIVSFGSPCSI 1063
>gi|189083786 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 35.8 bits (81), Expect = 0.14
Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 10/88 (11%)
Query: 11 PSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDREAGELPTSPLH 70
P ++P EE+E+D + GG Y + +S +E+ + E+ D+ AG P + ++
Sbjct: 983 PQAKPEEEQENDPV---GG----AGYKPQMHLPINSTVEDIAAEEDLDKTAGYRPQANVN 1035
Query: 71 ---LLSPGTPRSLDGSGSEPAVCEMCGI 95
L+SP +PRS+D + + C I
Sbjct: 1036 TWNLVSPDSPRSIDSNSEIVSFGSPCSI 1063
>gi|39653325 PHD finger protein 20-like 1 isoform 3 [Homo sapiens]
Length = 285
Score = 35.0 bits (79), Expect = 0.24
Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 10/75 (13%)
Query: 519 SKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHR--LLSIHFDGWDSE 576
SK P+R P F++G +LEA+D ++ + ++++ + + +HF+ W
Sbjct: 2 SKKPPNR------PGITFEIGARLEALDYLQKWY--PSRIEKIDYEEGKMLVHFERWSHR 53
Query: 577 YDQWVDCESPDIYPV 591
YD+W+ +S + P+
Sbjct: 54 YDEWIYWDSNRLRPL 68
>gi|109134330 PHD finger protein 20-like 1 isoform 2 [Homo sapiens]
Length = 573
Score = 35.0 bits (79), Expect = 0.24
Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 10/75 (13%)
Query: 519 SKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHR--LLSIHFDGWDSE 576
SK P+R P F++G +LEA+D ++ + ++++ + + +HF+ W
Sbjct: 2 SKKPPNR------PGITFEIGARLEALDYLQKWY--PSRIEKIDYEEGKMLVHFERWSHR 53
Query: 577 YDQWVDCESPDIYPV 591
YD+W+ +S + P+
Sbjct: 54 YDEWIYWDSNRLRPL 68
>gi|111120331 PHD finger protein 20-like 1 isoform 1 [Homo sapiens]
Length = 1017
Score = 35.0 bits (79), Expect = 0.24
Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 10/75 (13%)
Query: 519 SKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHR--LLSIHFDGWDSE 576
SK P+R P F++G +LEA+D ++ + ++++ + + +HF+ W
Sbjct: 2 SKKPPNR------PGITFEIGARLEALDYLQKWY--PSRIEKIDYEEGKMLVHFERWSHR 53
Query: 577 YDQWVDCESPDIYPV 591
YD+W+ +S + P+
Sbjct: 54 YDEWIYWDSNRLRPL 68
>gi|34996489 pleckstrin homology domain interacting protein [Homo
sapiens]
Length = 1821
Score = 35.0 bits (79), Expect = 0.24
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 16/87 (18%)
Query: 569 HFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAK-------EATKK 621
H DG S+Y W G LQPP KA+ E+ K+
Sbjct: 840 HSDGSSSDYSSDYS---------DWTADAGINLQPPKKVPKNKTKKAESSSDEEEESEKQ 890
Query: 622 KKKQFGKKRKRIPPTKTRPLRQGSKKP 648
K+KQ K++K++ K P+ KKP
Sbjct: 891 KQKQIKKEKKKVNEEKDGPISPKKKKP 917
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 34.7 bits (78), Expect = 0.31
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 5/91 (5%)
Query: 2 EKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLE---ESSEAENED 58
E+ +E+ + +EEED++ E G D +S SS+ + LE + S + E
Sbjct: 462 EEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQ 521
Query: 59 REAGELPTSPLHLLSPGTPRSLD--GSGSEP 87
+ G + + L P P S+D +G +P
Sbjct: 522 QNKGRIVSPSLLSEEPLAPSSIDAESNGEQP 552
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 34.7 bits (78), Expect = 0.31
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 5/91 (5%)
Query: 2 EKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLE---ESSEAENED 58
E+ +E+ + +EEED++ E G D +S SS+ + LE + S + E
Sbjct: 462 EEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQ 521
Query: 59 REAGELPTSPLHLLSPGTPRSLD--GSGSEP 87
+ G + + L P P S+D +G +P
Sbjct: 522 QNKGRIVSPSLLSEEPLAPSSIDAESNGEQP 552
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 34.7 bits (78), Expect = 0.31
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 5/91 (5%)
Query: 2 EKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLE---ESSEAENED 58
E+ +E+ + +EEED++ E G D +S SS+ + LE + S + E
Sbjct: 474 EEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQ 533
Query: 59 REAGELPTSPLHLLSPGTPRSLD--GSGSEP 87
+ G + + L P P S+D +G +P
Sbjct: 534 QNKGRIVSPSLLSEEPLAPSSIDAESNGEQP 564
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 33.9 bits (76), Expect = 0.53
Identities = 52/235 (22%), Positives = 84/235 (35%), Gaps = 43/235 (18%)
Query: 463 VDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAA 522
V GP +D ++ + SH+ F A F + I + + + + + +A+
Sbjct: 1999 VPDGPRSDSVEGSPFRPPSHS-FSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 2057
Query: 523 PSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIH---FDGWDSEYDQ 579
D N KV + ++ D V K + R LS+ FDG S +
Sbjct: 2058 -------DAKNQEGKVNTRRKSTD-------SVPISKSTLSRSLSLQASDFDGASSSGNP 2103
Query: 580 WVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTR 639
+PD Y G + + P+ LK K+ TKK PT+T
Sbjct: 2104 EAVALAPDAYSTGSSSASSTLKRTKKPRPPS--LKKKQTTKK-------------PTETP 2148
Query: 640 PLRQGSKKPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPV 694
P+++ ++P E S GE +A K E P A E P+
Sbjct: 2149 PVKETQQEPDEE----------SLVPSGENLASETKTESAKTEGPSPALLEETPL 2193
>gi|45827755 transforming, acidic coiled-coil containing protein 2
isoform b [Homo sapiens]
Length = 1094
Score = 33.9 bits (76), Expect = 0.53
Identities = 52/235 (22%), Positives = 84/235 (35%), Gaps = 43/235 (18%)
Query: 463 VDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAA 522
V GP +D ++ + SH+ F A F + I + + + + + +A+
Sbjct: 145 VPDGPRSDSVEGSPFRPPSHS-FSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 203
Query: 523 PSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIH---FDGWDSEYDQ 579
D N KV + ++ D V K + R LS+ FDG S +
Sbjct: 204 -------DAKNQEGKVNTRRKSTD-------SVPISKSTLSRSLSLQASDFDGASSSGNP 249
Query: 580 WVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTR 639
+PD Y G + + P+ LK K+ TKK PT+T
Sbjct: 250 EAVALAPDAYSTGSSSASSTLKRTKKPRPPS--LKKKQTTKK-------------PTETP 294
Query: 640 PLRQGSKKPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPV 694
P+++ ++P E S GE +A K E P A E P+
Sbjct: 295 PVKETQQEPDEE----------SLVPSGENLASETKTESAKTEGPSPALLEETPL 339
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,406,118
Number of Sequences: 37866
Number of extensions: 1496441
Number of successful extensions: 6657
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 6259
Number of HSP's gapped (non-prelim): 251
length of query: 705
length of database: 18,247,518
effective HSP length: 109
effective length of query: 596
effective length of database: 14,120,124
effective search space: 8415593904
effective search space used: 8415593904
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.