BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|20127624 NADPH oxidase, EF-hand calcium binding domain 5 [Homo sapiens] (747 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|20127624 NADPH oxidase, EF-hand calcium binding domain 5 [Hom... 1529 0.0 gi|132566532 dual oxidase 2 precursor [Homo sapiens] 248 1e-65 gi|20149640 dual oxidase 1 precursor [Homo sapiens] 231 2e-60 gi|28872751 dual oxidase 1 precursor [Homo sapiens] 231 2e-60 gi|148536873 NADPH oxidase 1 isoform long [Homo sapiens] 228 2e-59 gi|6996021 cytochrome b-245 beta polypeptide [Homo sapiens] 214 2e-55 gi|11136626 NADPH oxidase 3 [Homo sapiens] 209 1e-53 gi|7669510 NADPH oxidase 1 isoform long variant [Homo sapiens] 176 5e-44 gi|219842348 NADPH oxidase 4 isoform c [Homo sapiens] 119 1e-26 gi|8393843 NADPH oxidase 4 isoform a [Homo sapiens] 119 1e-26 gi|219842346 NADPH oxidase 4 isoform b [Homo sapiens] 69 2e-11 gi|40254415 guanylate cyclase activator 1A (retina) [Homo sapiens] 65 2e-10 gi|4506025 protein phosphatase 3, regulatory subunit B, alpha is... 55 3e-07 gi|98985795 neurocalcin delta [Homo sapiens] 50 1e-05 gi|98985793 neurocalcin delta [Homo sapiens] 50 1e-05 gi|98985791 neurocalcin delta [Homo sapiens] 50 1e-05 gi|98985789 neurocalcin delta [Homo sapiens] 50 1e-05 gi|98985787 neurocalcin delta [Homo sapiens] 50 1e-05 gi|98985785 neurocalcin delta [Homo sapiens] 50 1e-05 gi|98985783 neurocalcin delta [Homo sapiens] 50 1e-05 gi|98985778 neurocalcin delta [Homo sapiens] 50 1e-05 gi|19913443 hippocalcin-like 1 [Homo sapiens] 48 3e-05 gi|19913441 hippocalcin-like 1 [Homo sapiens] 48 3e-05 gi|153945858 guanylate cyclase activator 1B (retina) [Homo sapiens] 47 5e-05 gi|13375787 EF-hand calcium binding domain 1 isoform a [Homo sap... 47 6e-05 gi|19913446 hippocalcin [Homo sapiens] 46 1e-04 gi|33946291 lysophosphatidylcholine acyltransferase 1 [Homo sapi... 45 2e-04 gi|78190495 Kv channel interacting protein 3 isoform 2 [Homo sap... 44 4e-04 gi|7305199 Kv channel interacting protein 3 isoform 1 [Homo sapi... 44 4e-04 gi|22212896 protein phosphatase 3 regulatory subunit B, beta iso... 44 5e-04 >gi|20127624 NADPH oxidase, EF-hand calcium binding domain 5 [Homo sapiens] Length = 747 Score = 1530 bits (3960), Expect = 0.0 Identities = 747/747 (100%), Positives = 747/747 (100%) Query: 1 MSAEEDARWLRWVTQQFKTIAGEDGEISLQEFKAALHVKESFFAERFFALFDSDRSGTIT 60 MSAEEDARWLRWVTQQFKTIAGEDGEISLQEFKAALHVKESFFAERFFALFDSDRSGTIT Sbjct: 1 MSAEEDARWLRWVTQQFKTIAGEDGEISLQEFKAALHVKESFFAERFFALFDSDRSGTIT 60 Query: 61 LQELQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGS 120 LQELQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGS Sbjct: 61 LQELQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGS 120 Query: 121 GSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFP 180 GSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFP Sbjct: 121 GSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFP 180 Query: 181 GVMENLTISAAHWLTAPAPRPRPRRPRQLTRAYWHNHRSQLFCLATYAGLHVLLFGLAAS 240 GVMENLTISAAHWLTAPAPRPRPRRPRQLTRAYWHNHRSQLFCLATYAGLHVLLFGLAAS Sbjct: 181 GVMENLTISAAHWLTAPAPRPRPRRPRQLTRAYWHNHRSQLFCLATYAGLHVLLFGLAAS 240 Query: 241 AHRDLGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMG 300 AHRDLGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMG Sbjct: 241 AHRDLGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMG 300 Query: 301 YVVVGLSLVHTVAHTVNFVLQAQAEASPFQFWELLLTTRPGIGWVHGSASPTGVALLLLL 360 YVVVGLSLVHTVAHTVNFVLQAQAEASPFQFWELLLTTRPGIGWVHGSASPTGVALLLLL Sbjct: 301 YVVVGLSLVHTVAHTVNFVLQAQAEASPFQFWELLLTTRPGIGWVHGSASPTGVALLLLL 360 Query: 361 LLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHGPNFWKWLLVPGILFFLEKAIGL 420 LLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHGPNFWKWLLVPGILFFLEKAIGL Sbjct: 361 LLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHGPNFWKWLLVPGILFFLEKAIGL 420 Query: 421 AVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAP 480 AVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAP Sbjct: 421 AVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAP 480 Query: 481 EQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKH 540 EQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKH Sbjct: 481 EQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKH 540 Query: 541 KFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQ 600 KFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQ Sbjct: 541 KFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQ 600 Query: 601 HSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTS 660 HSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTS Sbjct: 601 HSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTS 660 Query: 661 ALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEKKGKVQVF 720 ALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEKKGKVQVF Sbjct: 661 ALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEKKGKVQVF 720 Query: 721 FCGSPALAKVLKGHCEKFGFRFFQENF 747 FCGSPALAKVLKGHCEKFGFRFFQENF Sbjct: 721 FCGSPALAKVLKGHCEKFGFRFFQENF 747 >gi|132566532 dual oxidase 2 precursor [Homo sapiens] Length = 1548 Score = 248 bits (633), Expect = 1e-65 Identities = 213/807 (26%), Positives = 352/807 (43%), Gaps = 176/807 (21%) Query: 26 EISLQEFKAALHVK-ESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLF 84 E+S EF +L +K + F E F+L D D +G ++ +E + L + + GSP DK + +F Sbjct: 805 ELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEDKSRLMF 864 Query: 85 QVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRESAISLP 144 +YD+D G + E+ S + + + +L V++S RES Sbjct: 865 TMYDLD---ENGFLSKDEFFT-----MMRSFIEISNNCLSKAQLAEVVESMFRESGF--- 913 Query: 145 DEKLDQLTLALFESADADGNGAITFEEL------------RDELQ-----------RFPG 181 + ++LT F D + + F +L RD + R PG Sbjct: 914 -QDKEELTWEDFHFMLRDHDSELRFTQLCVKGGGGGGNGIRDIFKQNISCRVSFITRTPG 972 Query: 182 VMENLTISAAHWLTAPAPR-------------------PRPR----------------RP 206 S L PAP P PR + Sbjct: 973 ER-----SHPQGLGPPAPEAPELGGPGLKKRFGKKAAVPTPRLYTEALQEKMQRGFLAQK 1027 Query: 207 RQLTRAYWHNHRSQLFCLATYAGLHVLLFGLAA------SAHRDLGASVMV----AKGCG 256 Q + + N+R + C+A ++ + V +F A S D+ + +V ++G Sbjct: 1028 LQQYKRFVENYRRHIVCVAIFSAICVGVFADRAYYYGFASPPSDIAQTTLVGIILSRGTA 1087 Query: 257 QCLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMGYVVVGLSLVHTVAHTV 316 ++F S+I + M R +T+LR T+L + +P D + FH+ + V L+++H+ H V Sbjct: 1088 ASVSFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRWIAMAAVVLAILHSAGHAV 1147 Query: 317 NFVLQAQAEAS-----------------PFQFWELLLTTRPGIGWVHGSASPTGVALLLL 359 N + + + S P +F+ T PG+ TGV LLL+ Sbjct: 1148 NVYIFSVSPLSLLACIFPNVFVNDGSKLPQKFYWWFFQTVPGM---------TGVLLLLV 1198 Query: 360 LLLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG-------PNFWKWLLVPGILF 412 L +M++ +S RR F F+ TH Y+L++ LLI HG P F + LVP I++ Sbjct: 1199 LAIMYVFASHHFRRRS-FRGFWLTHHLYILLYALLIIHGSYALIQLPTFHIYFLVPAIIY 1257 Query: 413 FLEKAIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWH 472 +K + L+ + + +++ LLPS VT+L +RP F Y+ G ++ + + E+H Sbjct: 1258 GGDKLVSLS-RKKVEISVVKAELLPSGVTYLQFQRPQGFEYKSGQWVRIACLALGTTEYH 1316 Query: 473 PFTISSAPEQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKG 532 PFT++SAP + DT+ LHIR+ G WT RL E + S P G G Sbjct: 1317 PFTLTSAPHE-DTLSLHIRAVGPWTTRLREIY--SSPKGNGCAGYP-------------- 1359 Query: 533 SEILLEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKR 592 K Y+DGP+G + E +VL+G GIG+TPFASIL+ ++++ Sbjct: 1360 -------------KLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFK---- 1402 Query: 593 KHTCPSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFL 652 + M K+ FIW+ R QR FEW ++ + EE + + Sbjct: 1403 ------------SSLGSQMLCKKIYFIWVTRTQRQFEWLADII-----QEVEENDHQDLV 1445 Query: 653 ELHMYMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVF---QKV 709 +H+Y+T K D++ L + + TGL++ T GRP + F Q+V Sbjct: 1446 SVHIYVTQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEV 1505 Query: 710 AAEKKGKVQVFFCGSPALAKVLKGHCE 736 + + K+ VF CG P + K ++ C+ Sbjct: 1506 HPQVR-KIGVFSCGPPGMTKNVEKACQ 1531 >gi|20149640 dual oxidase 1 precursor [Homo sapiens] Length = 1551 Score = 231 bits (588), Expect = 2e-60 Identities = 167/563 (29%), Positives = 270/563 (47%), Gaps = 94/563 (16%) Query: 208 QLTRAYWHNHRSQLFCLATYAGLHVLLF-----GLAASAHRD-----LGASVMVAKGCGQ 257 Q + + N+R + C+A + + LF A +AH +++++G Sbjct: 1032 QQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAA 1091 Query: 258 CLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMGYVVVGLSLVHTVAHTVN 317 ++F S+I + M R +T+LR T+L + +P D + FH+L+ + L+++H+V H VN Sbjct: 1092 SISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVLTVLHSVGHVVN 1151 Query: 318 FVLQAQAEASPFQFWELLLTTRPGIGWVHGSASP--------------TGVALLLLLLLM 363 L SP L PG+ GS P TGV LLL+L +M Sbjct: 1152 VYL---FSISPLSVLSCLF---PGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIM 1205 Query: 364 FICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG-------PNFWKWLLVPGILFFLEK 416 ++ +S RR F F+ TH Y+L+++LLI HG P F + LVP I++ +K Sbjct: 1206 YVFASHHFRRRS-FRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDK 1264 Query: 417 AIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTI 476 + L+ + + +++ LLPS VTHL +RP F Y+ G ++ + + E+HPFT+ Sbjct: 1265 LVSLS-RKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTL 1323 Query: 477 SSAPEQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEIL 536 +SAP + DT+ LHIR+ G WT RL E + A P G R Sbjct: 1324 TSAPHE-DTLSLHIRAAGPWTTRLREIYSA--PTGDRCARYP------------------ 1362 Query: 537 LEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTC 596 K Y+DGP+G + E +VL+G GIG+TPFASIL+ ++++ + Sbjct: 1363 ---------KLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFK------SS 1407 Query: 597 PSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHM 656 SCQ + K+ FIW+ R QR FEW ++ + EE + + +H+ Sbjct: 1408 VSCQ----------VFCKKIYFIWVTRTQRQFEWLADIIR-----EVEENDHQDLVSVHI 1452 Query: 657 YMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVF---QKVAAEK 713 Y+T K D++ L + + TGL++ T GRP + F Q+V + Sbjct: 1453 YITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQV 1512 Query: 714 KGKVQVFFCGSPALAKVLKGHCE 736 + K+ VF CG P + K ++ C+ Sbjct: 1513 R-KIGVFSCGPPGMTKNVEKACQ 1534 Score = 54.7 bits (130), Expect = 3e-07 Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 16/186 (8%) Query: 26 EISLQEFKAALHVK-ESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLF 84 E+S EF +L +K + F E F+L D D +G ++ +E + L + + GSP +K + +F Sbjct: 801 ELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEEKSRLMF 860 Query: 85 QVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRESAISLP 144 ++YD D G + E+ S + + + +L V++S RES Sbjct: 861 RMYDFD---GNGLISKDEF-----IRMLRSFIEISNNCLSKAQLAEVVESMFRESGF--- 909 Query: 145 DEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVMENLTISAAHW---LTAPAPRP 201 + ++LT F D N + F +L + P V+++L A++ + P+PR Sbjct: 910 -QDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQDMICPSPRV 968 Query: 202 RPRRPR 207 R R Sbjct: 969 SARCSR 974 >gi|28872751 dual oxidase 1 precursor [Homo sapiens] Length = 1551 Score = 231 bits (588), Expect = 2e-60 Identities = 167/563 (29%), Positives = 270/563 (47%), Gaps = 94/563 (16%) Query: 208 QLTRAYWHNHRSQLFCLATYAGLHVLLF-----GLAASAHRD-----LGASVMVAKGCGQ 257 Q + + N+R + C+A + + LF A +AH +++++G Sbjct: 1032 QQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAA 1091 Query: 258 CLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMGYVVVGLSLVHTVAHTVN 317 ++F S+I + M R +T+LR T+L + +P D + FH+L+ + L+++H+V H VN Sbjct: 1092 SISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVLTVLHSVGHVVN 1151 Query: 318 FVLQAQAEASPFQFWELLLTTRPGIGWVHGSASP--------------TGVALLLLLLLM 363 L SP L PG+ GS P TGV LLL+L +M Sbjct: 1152 VYL---FSISPLSVLSCLF---PGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIM 1205 Query: 364 FICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG-------PNFWKWLLVPGILFFLEK 416 ++ +S RR F F+ TH Y+L+++LLI HG P F + LVP I++ +K Sbjct: 1206 YVFASHHFRRRS-FRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDK 1264 Query: 417 AIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTI 476 + L+ + + +++ LLPS VTHL +RP F Y+ G ++ + + E+HPFT+ Sbjct: 1265 LVSLS-RKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTL 1323 Query: 477 SSAPEQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEIL 536 +SAP + DT+ LHIR+ G WT RL E + A P G R Sbjct: 1324 TSAPHE-DTLSLHIRAAGPWTTRLREIYSA--PTGDRCARYP------------------ 1362 Query: 537 LEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTC 596 K Y+DGP+G + E +VL+G GIG+TPFASIL+ ++++ + Sbjct: 1363 ---------KLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFK------SS 1407 Query: 597 PSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHM 656 SCQ + K+ FIW+ R QR FEW ++ + EE + + +H+ Sbjct: 1408 VSCQ----------VFCKKIYFIWVTRTQRQFEWLADIIR-----EVEENDHQDLVSVHI 1452 Query: 657 YMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVF---QKVAAEK 713 Y+T K D++ L + + TGL++ T GRP + F Q+V + Sbjct: 1453 YITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQV 1512 Query: 714 KGKVQVFFCGSPALAKVLKGHCE 736 + K+ VF CG P + K ++ C+ Sbjct: 1513 R-KIGVFSCGPPGMTKNVEKACQ 1534 Score = 54.7 bits (130), Expect = 3e-07 Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 16/186 (8%) Query: 26 EISLQEFKAALHVK-ESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLF 84 E+S EF +L +K + F E F+L D D +G ++ +E + L + + GSP +K + +F Sbjct: 801 ELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEEKSRLMF 860 Query: 85 QVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRESAISLP 144 ++YD D G + E+ S + + + +L V++S RES Sbjct: 861 RMYDFD---GNGLISKDEF-----IRMLRSFIEISNNCLSKAQLAEVVESMFRESGF--- 909 Query: 145 DEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVMENLTISAAHW---LTAPAPRP 201 + ++LT F D N + F +L + P V+++L A++ + P+PR Sbjct: 910 -QDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQDMICPSPRV 968 Query: 202 RPRRPR 207 R R Sbjct: 969 SARCSR 974 >gi|148536873 NADPH oxidase 1 isoform long [Homo sapiens] Length = 564 Score = 228 bits (580), Expect = 2e-59 Identities = 182/620 (29%), Positives = 279/620 (45%), Gaps = 150/620 (24%) Query: 216 NHRSQLFCLATYAGLHVLLFGLAASAHRD----------LGASVMVAKGCGQCLNFDCSF 265 NH + L + GL+V LF A + LG+++ A+ CLNF+ + Sbjct: 7 NHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTL 66 Query: 266 IAVLMLRRCLTWLRAT--WLAQVL--PLDQNIQFHQLMGYVVVGLSLVHTVAHTVNFVLQ 321 I + + R L++LR T + ++ L LD N+ FH+L+ Y++ + +H +AH NF Sbjct: 67 ILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCY 126 Query: 322 AQAEASPFQFWELLLTT-----RPGIGWVH---------------GSASPTGVALLLLLL 361 +++ + +L++ + G W++ A TGV + + L+ Sbjct: 127 SRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALI 186 Query: 362 LMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG----------------------- 398 LM ++ IRRS +FEVF++TH ++ L L HG Sbjct: 187 LMVTSATEFIRRS-YFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAE 245 Query: 399 ---------------------PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLP 437 P WKW+L P IL+ E+ + S+ V I +V + P Sbjct: 246 SFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVV-ITKVVMHP 304 Query: 438 SKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAPEQKDTIWLHIRSQGQWT 497 SKV L + + F G Y+++N P+I+ EWHPFT++SAPE+ D +HIR+ G WT Sbjct: 305 SKVLELQMNKRGF-SMEVGQYIFVNCPSISLLEWHPFTLTSAPEE-DFFSIHIRAAGDWT 362 Query: 498 NRLYESFKAS-DPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKHKFCNIKCYIDGPYGTP 556 L +F+ P+ R +DGP+GT Sbjct: 363 ENLIRAFEQQYSPIPR----------------------------------IEVDGPFGTA 388 Query: 557 TRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQHSWIEGVQDNMKLHKV 616 + +F E AVL+GAGIG+TPFASIL+SI Y+ Q H N+K K+ Sbjct: 389 SEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADH---------------NLKTKKI 433 Query: 617 DFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIGLQMAL 676 F WI R+ +F WF +LLT LE + E + G FL +++T D +G AL Sbjct: 434 YFYWICRETGAFSWFNNLLTSLEQEMEELGKVG-FLNYRLFLTGW----DSNIVG-HAAL 487 Query: 677 DLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVA-AEKKGKVQVFFCGSPALAKVLKGHC 735 + + D +TGL+ +T GRP W F +A + K V VF CG LAK L+ C Sbjct: 488 NF---DKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCC 544 Query: 736 EKFG--------FRFFQENF 747 ++ F F +ENF Sbjct: 545 HRYSSLDPRKVQFYFNKENF 564 >gi|6996021 cytochrome b-245 beta polypeptide [Homo sapiens] Length = 570 Score = 214 bits (546), Expect = 2e-55 Identities = 166/595 (27%), Positives = 270/595 (45%), Gaps = 134/595 (22%) Query: 216 NHRSQLFCLATYAGLHVLLFGLAASAH----------RDLGASVMVAKGCGQCLNFDCSF 265 N +F + + GL+V LF + + LG+++ +A+ CLNF+C Sbjct: 7 NEGLSIFVILVWLGLNVFLFVWYYRVYDIPPKFFYTRKLLGSALALARAPAACLNFNCML 66 Query: 266 IAVLMLRRCLTWLRATWLAQVL----PLDQNIQFHQLMGYVVVGLSLVHTVAHTVNFVLQ 321 I + + R L++LR + LD+N+ FH+++ +++ S +HT+AH N Sbjct: 67 ILLPVCRNLLSFLRGSSACCSTRVRRQLDRNLTFHKMVAWMIALHSAIHTIAHLFNVEWC 126 Query: 322 AQAEASPFQFWELLLT-------------TRPGIGWVHGS--------ASPTGVALLLLL 360 A + + + L+ R I G A TGV + L L Sbjct: 127 VNARVNNSDPYSVALSELGDRQNESYLNFARKRIKNPEGGLYLAVTLLAGITGVVITLCL 186 Query: 361 LLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG---------------------- 398 +L+ S+ IRRS +FEVF++TH +++ ++ L HG Sbjct: 187 ILIITSSTKTIRRS-YFEVFWYTHHLFVIFFIGLAIHGAERIVRGQTAESLAVHNITVCE 245 Query: 399 ---------------------PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLP 437 P WKW++ P L+ E+ + S+ V I +V P Sbjct: 246 QKISEWGKIKECPIPQFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQKVV-ITKVVTHP 304 Query: 438 SKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAPEQKDTIWLHIRSQGQWT 497 K L +K+ F G Y+++ P +++ EWHPFT++SAPE+ D +HIR G WT Sbjct: 305 FKTIELQMKKKGF-KMEVGQYIFVKCPKVSKLEWHPFTLTSAPEE-DFFSIHIRIVGDWT 362 Query: 498 NRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKHKFCNIKCYIDGPYGTPT 557 L+ + + + +L K +DGP+GT + Sbjct: 363 EGLFNACGCDKQEFQDAWKLP---------------------------KIAVDGPFGTAS 395 Query: 558 RRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQHSWIEGVQDNMKLHKVD 617 +F+ E +L+GAGIG+TPFASIL+S+ Y++ C ++ N+KL K+ Sbjct: 396 EDVFSYEVVMLVGAGIGVTPFASILKSVWYKY---------CNNA------TNLKLKKIY 440 Query: 618 FIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIGLQMALD 677 F W+ RD +FEWF LL LE Q +E FL ++Y+T G ++ +A + D Sbjct: 441 FYWLCRDTHAFEWFADLLQLLE-SQMQERNNAGFLSYNIYLT---GWDESQANHFAVHHD 496 Query: 678 LLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEKKG-KVQVFFCGSPALAKVL 731 E+KD ITGL+ +T GRP+W F+ +A++ ++ VF CG ALA+ L Sbjct: 497 -----EEKDVITGLKQKTLYGRPNWDNEFKTIASQHPNTRIGVFLCGPEALAETL 546 >gi|11136626 NADPH oxidase 3 [Homo sapiens] Length = 568 Score = 209 bits (531), Expect = 1e-53 Identities = 160/560 (28%), Positives = 255/560 (45%), Gaps = 121/560 (21%) Query: 245 LGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLP----LDQNIQFHQLMG 300 LG+++ A+ CLNF+C I + + R ++++R T + P LD+N++FH+L+ Sbjct: 47 LGSTLAWARASALCLNFNCMLILIPVSRNLISFIRGTSICCRGPWRRQLDKNLRFHKLVA 106 Query: 301 YVVVGLSLVHTVAHTVNFVLQAQAEASPFQFWELLLT------------------TRPGI 342 Y + + +H VAH N +++ Q L+ T Sbjct: 107 YGIAVNATIHIVAHFFNLERYHWSQSEEAQGLLAALSKLGNTPNESYLNPVRTFPTNTTT 166 Query: 343 GWVHGSASPTGVALLLLLLLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG---- 398 + A TG+ + L L+L+ S+ IR++ +E+F++TH +++ +L L HG Sbjct: 167 ELLRTIAGVTGLVISLALVLIMTSSTEFIRQAS-YELFWYTHHVFIVFFLSLAIHGTGRI 225 Query: 399 ---------------------------------------PNFWKWLLVPGILFFLEKAIG 419 P+ WKW+L P +L+ E+ I Sbjct: 226 VRGQTQDSLSLHNITFCRDRYAEWQTVAQCPVPQFSGKEPSAWKWILGPVVLYACERIIR 285 Query: 420 LAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSA 479 + V I +V PS V L +K+ F PG Y+ + P I+ EWHPFT++SA Sbjct: 286 FWRFQQEVV-ITKVVSHPSGVLELHMKKRGF-KMAPGQYILVQCPAISSLEWHPFTLTSA 343 Query: 480 PEQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEILLEK 539 P Q+D +HIR+ G WT L E+F A + L R Sbjct: 344 P-QEDFFSVHIRAAGDWTAALLEAFGAEGQALQEPWSLPRLA------------------ 384 Query: 540 HKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSC 599 +DGP+GT +F V + AGIG+TPFA++L+SI Y+ C Sbjct: 385 ---------VDGPFGTALTDVFHYPVCVCVAAGIGVTPFAALLKSIWYK----------C 425 Query: 600 QHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMT 659 + Q +KL KV F WI RD R+FEWF LL LE +E+ + FL H+++T Sbjct: 426 SEA-----QTPLKLSKVYFYWICRDARAFEWFADLLLSLETRMSEQGK-THFLSYHIFLT 479 Query: 660 SALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVA-AEKKGKVQ 718 G ++ +A+ + + D E D ITGL+ +T GRP+W+ F+++A + Sbjct: 480 ---GWDENQALHIALHWD-----ENTDVITGLKQKTFYGRPNWNNEFKQIAYNHPSSSIG 531 Query: 719 VFFCGSPALAKVLKGHCEKF 738 VFFCG AL++ L+ C + Sbjct: 532 VFFCGPKALSRTLQKMCHLY 551 >gi|7669510 NADPH oxidase 1 isoform long variant [Homo sapiens] Length = 515 Score = 176 bits (447), Expect = 5e-44 Identities = 163/620 (26%), Positives = 251/620 (40%), Gaps = 199/620 (32%) Query: 216 NHRSQLFCLATYAGLHVLLFGLAASAHRD----------LGASVMVAKGCGQCLNFDCSF 265 NH + L + GL+V LF A + LG+++ A+ CLNF+ + Sbjct: 7 NHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTL 66 Query: 266 IAVLMLRRCLTWLRAT--WLAQVL--PLDQNIQFHQLMGYVVVGLSLVHTVAHTVNFVLQ 321 I + + R L++LR T + ++ L LD N+ FH+L+ Y++ + +H +AH NF Sbjct: 67 ILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCY 126 Query: 322 AQAEASPFQFWELLLTT-----RPGIGWVH---------------GSASPTGVALLLLLL 361 +++ + +L++ + G W++ A TGV + + L+ Sbjct: 127 SRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALI 186 Query: 362 LMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG----------------------- 398 LM ++ IRRS +FEVF++TH ++ L L HG Sbjct: 187 LMVTSATEFIRRS-YFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAE 245 Query: 399 ---------------------PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLP 437 P WKW+L P IL+ E+ + S+ V I +V + P Sbjct: 246 SFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVV-ITKVVMHP 304 Query: 438 SKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAPEQKDTIWLHIRSQGQWT 497 SKV L + + F G Y+++N P+I+ EWHPFT++SAPE+ D +HIR+ G WT Sbjct: 305 SKVLELQMNKRGF-SMEVGQYIFVNCPSISLLEWHPFTLTSAPEE-DFFSIHIRAAGDWT 362 Query: 498 NRLYESFKAS-DPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKHKFCNIKCYIDGPYGTP 556 L +F+ P+ R +DGP+GT Sbjct: 363 ENLIRAFEQQYSPIPR----------------------------------IEVDGPFGTA 388 Query: 557 TRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQHSWIEGVQDNMKLHKV 616 + +F E AVL+GAGIG+TPFASIL+SI Y+ Q H N+K KV Sbjct: 389 SEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADH---------------NLKTKKV 433 Query: 617 DFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIGLQMAL 676 +N D+ A Sbjct: 434 GHAALNFDK-------------------------------------------------AT 444 Query: 677 DLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVA-AEKKGKVQVFFCGSPALAKVLKGHC 735 D++ ++K S GRP W F +A + K V VF CG LAK L+ C Sbjct: 445 DIVTGLKQKTSF---------GRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCC 495 Query: 736 EKFG--------FRFFQENF 747 ++ F F +ENF Sbjct: 496 HRYSSLDPRKVQFYFNKENF 515 >gi|219842348 NADPH oxidase 4 isoform c [Homo sapiens] Length = 554 Score = 119 bits (298), Expect = 1e-26 Identities = 101/349 (28%), Positives = 150/349 (42%), Gaps = 64/349 (18%) Query: 399 PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDY 458 P W W+ P L+ E+ S V I+ V PS V + + + F RPG Y Sbjct: 257 PQTWLWISGPLCLYCAERLYRYIRSNKP-VTIISVISHPSDVMEIRMVKENF-KARPGQY 314 Query: 459 LYLNIPTIARYEWHPFTISSAP-EQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRL 517 + L+ P+++ E HPFT++ P E K T +H++ G WT R + Sbjct: 315 ITLHCPSVSALENHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLPP---------- 364 Query: 518 SRSVTMRKSQRSSKGSEILLEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITP 577 SS+ SEIL K YIDGP+G+P E ++ + GIG+TP Sbjct: 365 -----------SSQDSEILPFIQSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTP 413 Query: 578 FASILQSIMYRHQKRKHTCPSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTK 637 FASIL +++ W KL ++ FIW+ RD +SF WF LL Sbjct: 414 FASILNTLL--------------DDW-----KPYKLRRLYFIWVCRDIQSFRWFADLLCM 454 Query: 638 LEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQP 697 L +E + ++ + +Y++ G K IG + L +R Sbjct: 455 LHNKFWQENR-PDYVNIQLYLSQTDG--IQKIIG--------------EKYHALNSRLFI 497 Query: 698 GRPDWSKVFQKVAAEKKGK-VQVFFCGSPALAKV---LKGHCEKFGFRF 742 GRP W +F ++A +GK V VF CG +L+K L +G RF Sbjct: 498 GRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKTLHKLSNQNNSYGTRF 546 Score = 66.2 bits (160), Expect = 1e-10 Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 31/174 (17%) Query: 242 HRDLGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLP-------LDQNIQ 294 H+ LG + +++ LN +CS I + M R L +LR + Q +P LD++ Sbjct: 23 HQMLGLGLCLSRASASVLNLNCSLILLPMCRTLLAYLRGS---QKVPSRRTRRLLDKSRT 79 Query: 295 FHQLMGYVVVGLSLVHTVAHTVN-----------FVLQAQAEASPFQFWELLLTTRPGIG 343 FH G + S VH AH VN FV A +LL TT PG+ Sbjct: 80 FHITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVPGL- 138 Query: 344 WVHGSASPTGVALLLLLLLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFH 397 TGV ++++L LM S+ IR S ++++F++TH + + ++LL H Sbjct: 139 --------TGVCMVVVLFLMITASTYAIRVS-NYDIFWYTHNLFFVFYMLLTLH 183 >gi|8393843 NADPH oxidase 4 isoform a [Homo sapiens] Length = 578 Score = 119 bits (298), Expect = 1e-26 Identities = 101/349 (28%), Positives = 150/349 (42%), Gaps = 64/349 (18%) Query: 399 PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDY 458 P W W+ P L+ E+ S V I+ V PS V + + + F RPG Y Sbjct: 281 PQTWLWISGPLCLYCAERLYRYIRSNKP-VTIISVISHPSDVMEIRMVKENF-KARPGQY 338 Query: 459 LYLNIPTIARYEWHPFTISSAP-EQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRL 517 + L+ P+++ E HPFT++ P E K T +H++ G WT R + Sbjct: 339 ITLHCPSVSALENHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLPP---------- 388 Query: 518 SRSVTMRKSQRSSKGSEILLEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITP 577 SS+ SEIL K YIDGP+G+P E ++ + GIG+TP Sbjct: 389 -----------SSQDSEILPFIQSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTP 437 Query: 578 FASILQSIMYRHQKRKHTCPSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTK 637 FASIL +++ W KL ++ FIW+ RD +SF WF LL Sbjct: 438 FASILNTLL--------------DDW-----KPYKLRRLYFIWVCRDIQSFRWFADLLCM 478 Query: 638 LEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQP 697 L +E + ++ + +Y++ G K IG + L +R Sbjct: 479 LHNKFWQENR-PDYVNIQLYLSQTDG--IQKIIG--------------EKYHALNSRLFI 521 Query: 698 GRPDWSKVFQKVAAEKKGK-VQVFFCGSPALAKV---LKGHCEKFGFRF 742 GRP W +F ++A +GK V VF CG +L+K L +G RF Sbjct: 522 GRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKTLHKLSNQNNSYGTRF 570 Score = 68.6 bits (166), Expect = 2e-11 Identities = 60/215 (27%), Positives = 96/215 (44%), Gaps = 41/215 (19%) Query: 211 RAYWHNHRSQLFCLATYAGLHVLLFGLAASA----------HRDLGASVMVAKGCGQCLN 260 R++ N + CL + ++VLLF H+ LG + +++ LN Sbjct: 6 RSWLANEGVKHLCLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRASASVLN 65 Query: 261 FDCSFIAVLMLRRCLTWLRATWLAQVLP-------LDQNIQFHQLMGYVVVGLSLVHTVA 313 +CS I + M R L +LR + Q +P LD++ FH G + S VH A Sbjct: 66 LNCSLILLPMCRTLLAYLRGS---QKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHVAA 122 Query: 314 HTVN-----------FVLQAQAEASPFQFWELLLTTRPGIGWVHGSASPTGVALLLLLLL 362 H VN FV A +LL TT PG+ TGV ++++L L Sbjct: 123 HLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVPGL---------TGVCMVVVLFL 173 Query: 363 MFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFH 397 M S+ IR S ++++F++TH + + ++LL H Sbjct: 174 MITASTYAIRVS-NYDIFWYTHNLFFVFYMLLTLH 207 >gi|219842346 NADPH oxidase 4 isoform b [Homo sapiens] Length = 538 Score = 68.6 bits (166), Expect = 2e-11 Identities = 60/215 (27%), Positives = 96/215 (44%), Gaps = 41/215 (19%) Query: 211 RAYWHNHRSQLFCLATYAGLHVLLFGLAASA----------HRDLGASVMVAKGCGQCLN 260 R++ N + CL + ++VLLF H+ LG + +++ LN Sbjct: 6 RSWLANEGVKHLCLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRASASVLN 65 Query: 261 FDCSFIAVLMLRRCLTWLRATWLAQVLP-------LDQNIQFHQLMGYVVVGLSLVHTVA 313 +CS I + M R L +LR + Q +P LD++ FH G + S VH A Sbjct: 66 LNCSLILLPMCRTLLAYLRGS---QKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHVAA 122 Query: 314 HTVN-----------FVLQAQAEASPFQFWELLLTTRPGIGWVHGSASPTGVALLLLLLL 362 H VN FV A +LL TT PG+ TGV ++++L L Sbjct: 123 HLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVPGL---------TGVCMVVVLFL 173 Query: 363 MFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFH 397 M S+ IR S ++++F++TH + + ++LL H Sbjct: 174 MITASTYAIRVS-NYDIFWYTHNLFFVFYMLLTLH 207 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 3/102 (2%) Query: 399 PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDY 458 P W W+ P L+ E+ S V I+ V PS V + + + F RPG Y Sbjct: 281 PQTWLWISGPLCLYCAERLYRYIRSNKP-VTIISVISHPSDVMEIRMVKENF-KARPGQY 338 Query: 459 LYLNIPTIARYEWHPFTISSAP-EQKDTIWLHIRSQGQWTNR 499 + L+ P+++ E HPFT++ P E K T +H++ G WT R Sbjct: 339 ITLHCPSVSALENHPFTLTMCPTETKATFGVHLKIVGDWTER 380 Score = 53.9 bits (128), Expect = 5e-07 Identities = 41/135 (30%), Positives = 62/135 (45%), Gaps = 21/135 (15%) Query: 612 KLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIG 671 KL ++ FIW+ RD +SF WF LL L +E + ++ + +Y++ G K IG Sbjct: 413 KLRRLYFIWVCRDIQSFRWFADLLCMLHNKFWQENR-PDYVNIQLYLSQTDG--IQKIIG 469 Query: 672 LQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEKKGK-VQVFFCGSPALAKV 730 + L +R GRP W +F ++A +GK V VF CG +L+K Sbjct: 470 --------------EKYHALNSRLFIGRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKT 515 Query: 731 ---LKGHCEKFGFRF 742 L +G RF Sbjct: 516 LHKLSNQNNSYGTRF 530 >gi|40254415 guanylate cyclase activator 1A (retina) [Homo sapiens] Length = 201 Score = 65.1 bits (157), Expect = 2e-10 Identities = 44/170 (25%), Positives = 79/170 (46%), Gaps = 33/170 (19%) Query: 25 GEISLQEFKAALHVKE-----SFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G+++L EF+ +K S + E+ F FD ++ G I E AL+L++ G K Sbjct: 32 GQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQK 91 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRES 139 L++ F++YD+D G+G ID DEL T++Q+ + Sbjct: 92 LRWYFKLYDVD----------------------------GNGCIDRDELLTIIQAIRAIN 123 Query: 140 AISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVMENLTIS 189 S ++ T +F D +G+G ++ EE + +Q+ +++ LT S Sbjct: 124 PCSDTTMTAEEFTDTVFSKIDVNGDGELSLEEFIEGVQKDQMLLDTLTRS 173 >gi|4506025 protein phosphatase 3, regulatory subunit B, alpha isoform 1 [Homo sapiens] Length = 170 Score = 54.7 bits (130), Expect = 3e-07 Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 33/173 (19%) Query: 1 MSAEEDARWLRWVTQQFKTI-AGEDGEISLQEFKAALHVKESFFAERFFALFDSDRSGTI 59 M + DA ++ + ++FK + G +S++EF + ++++ +R +FD+D +G + Sbjct: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEV 70 Query: 60 TLQELQEALT-LLIHGSPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGT 118 +E E ++ + G KL+F F++YD+D Sbjct: 71 DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMD---------------------------- 102 Query: 119 GSGSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEE 171 G I EL VL+ + +L D +L Q+ +AD DG+G I+FEE Sbjct: 103 KDGYISNGELFQVLKMMVGN---NLKDTQLQQIVDKTIINADKDGDGRISFEE 152 >gi|98985795 neurocalcin delta [Homo sapiens] Length = 193 Score = 49.7 bits (117), Expect = 1e-05 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%) Query: 25 GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G +S++EFK + S FAE F FD++ GTI +E AL++ G K Sbjct: 41 GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137 LK+ F +YD+D G+G I E+ ++Q+ + Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132 Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186 S + +P+++ ++ T +F D + +G ++ EE + P ++ L Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183 >gi|98985793 neurocalcin delta [Homo sapiens] Length = 193 Score = 49.7 bits (117), Expect = 1e-05 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%) Query: 25 GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G +S++EFK + S FAE F FD++ GTI +E AL++ G K Sbjct: 41 GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137 LK+ F +YD+D G+G I E+ ++Q+ + Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132 Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186 S + +P+++ ++ T +F D + +G ++ EE + P ++ L Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183 >gi|98985791 neurocalcin delta [Homo sapiens] Length = 193 Score = 49.7 bits (117), Expect = 1e-05 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%) Query: 25 GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G +S++EFK + S FAE F FD++ GTI +E AL++ G K Sbjct: 41 GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137 LK+ F +YD+D G+G I E+ ++Q+ + Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132 Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186 S + +P+++ ++ T +F D + +G ++ EE + P ++ L Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183 >gi|98985789 neurocalcin delta [Homo sapiens] Length = 193 Score = 49.7 bits (117), Expect = 1e-05 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%) Query: 25 GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G +S++EFK + S FAE F FD++ GTI +E AL++ G K Sbjct: 41 GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137 LK+ F +YD+D G+G I E+ ++Q+ + Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132 Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186 S + +P+++ ++ T +F D + +G ++ EE + P ++ L Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183 >gi|98985787 neurocalcin delta [Homo sapiens] Length = 193 Score = 49.7 bits (117), Expect = 1e-05 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%) Query: 25 GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G +S++EFK + S FAE F FD++ GTI +E AL++ G K Sbjct: 41 GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137 LK+ F +YD+D G+G I E+ ++Q+ + Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132 Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186 S + +P+++ ++ T +F D + +G ++ EE + P ++ L Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183 >gi|98985785 neurocalcin delta [Homo sapiens] Length = 193 Score = 49.7 bits (117), Expect = 1e-05 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%) Query: 25 GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G +S++EFK + S FAE F FD++ GTI +E AL++ G K Sbjct: 41 GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137 LK+ F +YD+D G+G I E+ ++Q+ + Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132 Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186 S + +P+++ ++ T +F D + +G ++ EE + P ++ L Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183 >gi|98985783 neurocalcin delta [Homo sapiens] Length = 193 Score = 49.7 bits (117), Expect = 1e-05 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%) Query: 25 GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G +S++EFK + S FAE F FD++ GTI +E AL++ G K Sbjct: 41 GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137 LK+ F +YD+D G+G I E+ ++Q+ + Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132 Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186 S + +P+++ ++ T +F D + +G ++ EE + P ++ L Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183 >gi|98985778 neurocalcin delta [Homo sapiens] Length = 193 Score = 49.7 bits (117), Expect = 1e-05 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%) Query: 25 GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G +S++EFK + S FAE F FD++ GTI +E AL++ G K Sbjct: 41 GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137 LK+ F +YD+D G+G I E+ ++Q+ + Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132 Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186 S + +P+++ ++ T +F D + +G ++ EE + P ++ L Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183 >gi|19913443 hippocalcin-like 1 [Homo sapiens] Length = 193 Score = 48.1 bits (113), Expect = 3e-05 Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 37/171 (21%) Query: 25 GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G +++ EFK + S FAE F FD++ GTI +E AL++ G K Sbjct: 41 GHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQK 100 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137 LK+ F +YD+D G+G I E+ ++Q+ + Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISRSEMLEIVQAIYKMV 132 Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186 S + +P+++ ++ T +F D + +G ++ EE + P ++ L Sbjct: 133 SSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLL 183 >gi|19913441 hippocalcin-like 1 [Homo sapiens] Length = 193 Score = 48.1 bits (113), Expect = 3e-05 Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 37/171 (21%) Query: 25 GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G +++ EFK + S FAE F FD++ GTI +E AL++ G K Sbjct: 41 GHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQK 100 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137 LK+ F +YD+D G+G I E+ ++Q+ + Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISRSEMLEIVQAIYKMV 132 Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186 S + +P+++ ++ T +F D + +G ++ EE + P ++ L Sbjct: 133 SSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLL 183 >gi|153945858 guanylate cyclase activator 1B (retina) [Homo sapiens] Length = 200 Score = 47.4 bits (111), Expect = 5e-05 Identities = 46/188 (24%), Positives = 79/188 (42%), Gaps = 50/188 (26%) Query: 25 GEISLQEFKAALHVKE----SFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKL 80 G + + EFK V + S + E F FD + TI E AL L++ G+ KL Sbjct: 35 GTLFMHEFKRFFKVTDDEEASQYVEGMFRAFDKNGDNTIDFLEYVAALNLVLRGTLEHKL 94 Query: 81 KFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQ------- 133 K+ F++YD D G+G ID EL +++ Sbjct: 95 KWTFKIYDKD----------------------------GNGCIDRLELLNIVEGIYQLKK 126 Query: 134 SCLRE-----SAISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVME--NL 186 +C RE + P+E +D++ L + D +G+G ++ E + +R VM+ + Sbjct: 127 ACRRELQTEQGQLLTPEEVVDRIFLLV----DENGDGQLSLNEFVEGARRDKWVMKMLQM 182 Query: 187 TISAAHWL 194 ++ + WL Sbjct: 183 DMNPSSWL 190 >gi|13375787 EF-hand calcium binding domain 1 isoform a [Homo sapiens] Length = 211 Score = 47.0 bits (110), Expect = 6e-05 Identities = 35/145 (24%), Positives = 62/145 (42%), Gaps = 33/145 (22%) Query: 32 FKAALHVK----ESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLFQVY 87 F+ LHV + +R F FD D G + + E L+L + GS +K+K+ F+V+ Sbjct: 53 FRNILHVTFGMTDDMIMDRVFRGFDKDNDGCVNVLEWIHGLSLFLRGSLEEKMKYCFEVF 112 Query: 88 DIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQ-SCLRESAISLPDE 146 D++ G G I +E+ +L+ S L++ + PDE Sbjct: 113 DLN----------------------------GDGFISKEEMFHMLKNSLLKQPSEEDPDE 144 Query: 147 KLDQLTLALFESADADGNGAITFEE 171 + L + D D +G ++F + Sbjct: 145 GIKDLVEITLKKMDHDHDGKLSFAD 169 >gi|19913446 hippocalcin [Homo sapiens] Length = 193 Score = 45.8 bits (107), Expect = 1e-04 Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 37/171 (21%) Query: 25 GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79 G +++ EFK + S FAE F FD++ GTI +E AL++ G K Sbjct: 41 GILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQK 100 Query: 80 LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137 L + F +YD+D G+G I +E+ ++Q+ + Sbjct: 101 LMWAFSMYDLD----------------------------GNGYISREEMLEIVQAIYKMV 132 Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186 S + +P+++ ++ T +F D + +G ++ EE + P ++ L Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLL 183 >gi|33946291 lysophosphatidylcholine acyltransferase 1 [Homo sapiens] Length = 534 Score = 45.4 bits (106), Expect = 2e-04 Identities = 45/182 (24%), Positives = 75/182 (41%), Gaps = 43/182 (23%) Query: 26 EISLQEFKAALHVKESFFAERFFALFDSDRSGTITLQELQEALTLLIH-GSPMDKLKFLF 84 +I + EF A+L V S E F+LFD SG + L+E AL+++ +D ++ F Sbjct: 366 KIGIAEFAASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDTIQLAF 425 Query: 85 QVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRESAISLP 144 ++Y GA GS+ +L +L++ L + +++ Sbjct: 426 KMY--------GAQE--------------------DGSVGEGDLSCILKTALGVAELTVT 457 Query: 145 DEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVMEN-LTISAAHW----LTAPAP 199 D LF + D + G ITF + + +P E L H+ T+PAP Sbjct: 458 D---------LFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYPDQTHFESCAETSPAP 508 Query: 200 RP 201 P Sbjct: 509 IP 510 >gi|78190495 Kv channel interacting protein 3 isoform 2 [Homo sapiens] Length = 230 Score = 44.3 bits (103), Expect = 4e-04 Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 46/157 (29%) Query: 43 FAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTE 102 +A F FD+D +G I ++ L++L+ G+ +KLK+ F +YDI+ Sbjct: 104 YAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDIN------------ 151 Query: 103 WGAGAGPHWASSPLGTGSGSIDPDELRTVLQS-----------CLRESAISLPDEKLDQL 151 G I +E+ +++S LRE A P E +++ Sbjct: 152 ----------------KDGYITKEEMLAIMKSIYDMMGRHTYPILREDA---PAEHVER- 191 Query: 152 TLALFESADADGNGAITFEELRDELQRFPGVMENLTI 188 FE D + +G +T EE + Q+ +M ++ + Sbjct: 192 ---FFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQL 225 >gi|7305199 Kv channel interacting protein 3 isoform 1 [Homo sapiens] Length = 256 Score = 44.3 bits (103), Expect = 4e-04 Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 46/157 (29%) Query: 43 FAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTE 102 +A F FD+D +G I ++ L++L+ G+ +KLK+ F +YDI+ Sbjct: 130 YAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDIN------------ 177 Query: 103 WGAGAGPHWASSPLGTGSGSIDPDELRTVLQS-----------CLRESAISLPDEKLDQL 151 G I +E+ +++S LRE A P E +++ Sbjct: 178 ----------------KDGYITKEEMLAIMKSIYDMMGRHTYPILREDA---PAEHVER- 217 Query: 152 TLALFESADADGNGAITFEELRDELQRFPGVMENLTI 188 FE D + +G +T EE + Q+ +M ++ + Sbjct: 218 ---FFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQL 251 >gi|22212896 protein phosphatase 3 regulatory subunit B, beta isoform [Homo sapiens] Length = 173 Score = 43.9 bits (102), Expect = 5e-04 Identities = 41/173 (23%), Positives = 71/173 (41%), Gaps = 33/173 (19%) Query: 1 MSAEEDARWLRWVTQQFKTI-AGEDGEISLQEFKAALHVKESFFAERFFALFDSDRSGTI 59 M + D ++ + ++FK + + G +S++EF + ++ + R +FD+D G + Sbjct: 14 MCSHFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRRVIDVFDTDGDGEV 73 Query: 60 TLQE-LQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGT 118 +E + + G KL+F F +YD+D Sbjct: 74 DFKEFILGTSQFSVKGDEEQKLRFAFSIYDMD---------------------------- 105 Query: 119 GSGSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEE 171 G I EL VL+ + +L D +L QL D DG+G I+FEE Sbjct: 106 KDGYISNGELFQVLKMMVGN---NLTDWQLQQLVDKTIIILDKDGDGKISFEE 155 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.137 0.436 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,673,225 Number of Sequences: 37866 Number of extensions: 1355923 Number of successful extensions: 5037 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 66 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 4771 Number of HSP's gapped (non-prelim): 221 length of query: 747 length of database: 18,247,518 effective HSP length: 110 effective length of query: 637 effective length of database: 14,082,258 effective search space: 8970398346 effective search space used: 8970398346 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.