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Search of human proteins with 20070205
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20070205 ladinin 1 [Homo sapiens]
(517 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20070205 ladinin 1 [Homo sapiens] 988 0.0
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 90 6e-18
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 88 2e-17
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 83 7e-16
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 81 3e-15
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 81 3e-15
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 69 1e-11
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 66 7e-11
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 59 1e-08
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 57 5e-08
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 56 9e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 55 2e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 54 3e-07
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 54 4e-07
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ... 54 4e-07
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ... 54 4e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 53 8e-07
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 53 8e-07
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 53 8e-07
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 53 8e-07
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 52 1e-06
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 52 1e-06
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 52 1e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 51 3e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 51 3e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 51 3e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 51 3e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 51 3e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 51 3e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 51 3e-06
>gi|20070205 ladinin 1 [Homo sapiens]
Length = 517
Score = 988 bits (2555), Expect = 0.0
Identities = 517/517 (100%), Positives = 517/517 (100%)
Query: 1 MAVSRKDWSALSSLARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASE 60
MAVSRKDWSALSSLARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASE
Sbjct: 1 MAVSRKDWSALSSLARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASE 60
Query: 61 RLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRN 120
RLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRN
Sbjct: 61 RLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRN 120
Query: 121 SLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVL 180
SLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVL
Sbjct: 121 SLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVL 180
Query: 181 EKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSE 240
EKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSE
Sbjct: 181 EKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSE 240
Query: 241 KSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGG 300
KSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGG
Sbjct: 241 KSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGG 300
Query: 301 SPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQR 360
SPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQR
Sbjct: 301 SPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQR 360
Query: 361 TYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKLERYHTAIRRSES 420
TYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKLERYHTAIRRSES
Sbjct: 361 TYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKLERYHTAIRRSES 420
Query: 421 VKSRGLPCTELFVAPVGVASKRHLFEKELAGQSRAEPASSRKENLRLSGVVTSRLNLWIS 480
VKSRGLPCTELFVAPVGVASKRHLFEKELAGQSRAEPASSRKENLRLSGVVTSRLNLWIS
Sbjct: 421 VKSRGLPCTELFVAPVGVASKRHLFEKELAGQSRAEPASSRKENLRLSGVVTSRLNLWIS 480
Query: 481 RTQESGDQDPQEAQKASSATERTQWGQKSDSSLDAEV 517
RTQESGDQDPQEAQKASSATERTQWGQKSDSSLDAEV
Sbjct: 481 RTQESGDQDPQEAQKASSATERTQWGQKSDSSLDAEV 517
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 89.7 bits (221), Expect = 6e-18
Identities = 120/546 (21%), Positives = 217/546 (39%), Gaps = 48/546 (8%)
Query: 5 RKDWSALSSLARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDR-QASASERLP 63
R+ +ALS +A QR +DEEE RERRRR R E L Q D+ + +A +P
Sbjct: 10 RRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVP 69
Query: 64 SVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRR-------------QVVEAAQAPIQ 110
EEA+ D++ L R+ERRQ+R + +A+ +
Sbjct: 70 D-EEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPS 128
Query: 111 ERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSRE-QRGPWA-LEEESLVGREPEE 168
R++ + N + + +K ++ EI +++ Q+ W EE +E EE
Sbjct: 129 RRMQNDTAENETT--EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE 186
Query: 169 RKKGVPEKSPVLEKSSMPKKT---APEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRN 225
++ P++ + E K T A + L DK + ++ + EK ++ K
Sbjct: 187 EEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSF 246
Query: 226 SSEKKSVLEKTSVSEKSLAPGM-------ALGSGRRLVSEKASIFEKALASEKSPTADAK 278
KK E S + + + + + GR V K + E A E +
Sbjct: 247 MDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEA--EGAPQVEAGKRLEEL 304
Query: 279 PAPKRATASEQ-----PLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASD----P 329
+ T SE+ QE +E+R + L + KQ +D
Sbjct: 305 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE--QRRKQEEADRKLRE 362
Query: 330 PTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTL 389
RL + + + E+ M K +P+ S +++ + E ++
Sbjct: 363 EEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSV 422
Query: 390 TRSASMKLPDNTV---KLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFE 446
+S+ +K K+ +LE+Y +AI ++S K ++L V GV + + ++E
Sbjct: 423 QKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWE 482
Query: 447 KELAGQSRAEPASSRKENLRLSGVVTSRLNLWISRT---QESGDQDPQEAQKASSATERT 503
K S + KE L V+SR+N W+++T +S P + + +++R
Sbjct: 483 KGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRN 542
Query: 504 QWGQKS 509
W ++S
Sbjct: 543 LWEKQS 548
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 87.8 bits (216), Expect = 2e-17
Identities = 116/539 (21%), Positives = 222/539 (41%), Gaps = 60/539 (11%)
Query: 5 RKDWSALSSLARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDR-QASASERLP 63
R+ +ALS +A QR +DEEE RERRRR R E L Q D+ + +A +P
Sbjct: 10 RRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVP 69
Query: 64 SVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRR-------------QVVEAAQAPIQ 110
EEA+ D++ L R+ERRQ+R + +A+ +
Sbjct: 70 D-EEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPS 128
Query: 111 ERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSRE-QRGPWA-LEEESLVGREPEE 168
R++ + N + + +K ++ EI +++ Q+ W EE +E EE
Sbjct: 129 RRMQNDTAENETT--EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE 186
Query: 169 RKKGVPEKSPV---------LEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIA 219
++ P++ + ++K PK+ KS + K +E V + ++ K+
Sbjct: 187 EEEEKPKRGSIGENQIKDEKIKKDKEPKEEV--KSFMDRKKGFTE-VKSQNGEFMTHKLK 243
Query: 220 VSEKRNS--SEKKSVLEKTSVSEKSLAPGMALGSGRRLVSE-KASIFEKALASEKSPTAD 276
+E S + SV K + + G L RR E ++ FEK ++ +
Sbjct: 244 HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALE 303
Query: 277 AKPAPKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRL 336
+ K+ + L +E +++R + + L ++ R
Sbjct: 304 LEELKKKREERRKVLEEE-----------EQRRKQEEADRKLREEEEKRRLKEEIERRRA 352
Query: 337 PPVTLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMK 396
+ K+P ++ +D P K +P+ S +++ + E ++ +S+ +K
Sbjct: 353 EAAEKRQKMP-EDGLSDDKKP--------FKCFTPKGSSLKIEERAEFLNKSVQKSSGVK 403
Query: 397 LPDNTV---KLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEKELAGQS 453
K+ +LE+Y +AI ++S K ++L V GV + + ++EK S
Sbjct: 404 STHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSS 463
Query: 454 RAEPASSRKENLRLSGVVTSRLNLWISRT---QESGDQDPQEAQKASSATERTQWGQKS 509
+ KE L V+SR+N W+++T +S P + + +++R W ++S
Sbjct: 464 PTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQS 522
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 82.8 bits (203), Expect = 7e-16
Identities = 116/537 (21%), Positives = 211/537 (39%), Gaps = 48/537 (8%)
Query: 14 LARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDR-QASASERLPSVEEAEVPK 72
+A QR +DEEE RERRRR R E L Q D+ + +A +P EEA+
Sbjct: 25 IAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPD-EEAKTTT 83
Query: 73 PLPPASKDEDEDIQSILRTRQERRQRR-------------QVVEAAQAPIQERLEAEEGR 119
D++ L R+ERRQ+R + +A+ + R++ +
Sbjct: 84 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 143
Query: 120 NSLSPVQATQKPLVSKKELEIPPRRRLSRE-QRGPWA-LEEESLVGREPEERKKGVPEKS 177
N + + +K ++ EI +++ Q+ W EE +E EE ++ P++
Sbjct: 144 NETT--EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 201
Query: 178 PVLEKSSMPKKT---APEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLE 234
+ E K T A + L DK + ++ + EK ++ K KK E
Sbjct: 202 SIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTE 261
Query: 235 KTSVSEKSLAPGM-------ALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATAS 287
S + + + + + GR V K + E A E + + T S
Sbjct: 262 VKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEA--EGAPQVEAGKRLEELRRRRGETES 319
Query: 288 EQ-----PLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASD----PPTVASRLPP 338
E+ QE +E+R + L + KQ +D RL
Sbjct: 320 EEFEKLKQKQQEAALELEELKKKREERRKVLEEEE--QRRKQEEADRKLREEEEKRRLKE 377
Query: 339 VTLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLP 398
+ + + E+ M K +P+ S +++ + E ++ +S+ +K
Sbjct: 378 EIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKST 437
Query: 399 DNTV---KLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEKELAGQSRA 455
K+ +LE+Y +AI ++S K ++L V GV + + ++EK S
Sbjct: 438 HQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPT 497
Query: 456 EPASSRKENLRLSGVVTSRLNLWISRT---QESGDQDPQEAQKASSATERTQWGQKS 509
+ KE L V+SR+N W+++T +S P + + +++R W ++S
Sbjct: 498 AAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQS 554
Score = 31.6 bits (70), Expect = 1.8
Identities = 63/309 (20%), Positives = 114/309 (36%), Gaps = 66/309 (21%)
Query: 90 RTRQERRQRRQVVEAAQAPIQERLEAEE---GRNSLSPVQATQKPLVSKKELEIPPRRRL 146
R R+ RRQ+R+ + RLEAE RN +A ++ RRR
Sbjct: 6 RRRELRRQKRE---------EMRLEAERIAYQRNDDDEEEAARE------------RRRR 44
Query: 147 SREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKV 206
+R++R EEESL V ++ V ++S+P + A T+ + +V
Sbjct: 45 ARQERLRQKQEEESL---------GQVTDQVEVNAQNSVPDEEAKT-------TTTNTQV 88
Query: 207 LASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKA--SIFE 264
++ + E++A E+R + LE+ + ++ RR+ ++ A E
Sbjct: 89 EGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTE 148
Query: 265 KALASE-------------------KSPTADAKPAPKRATASEQPLAQEPPASG-----G 300
K SE K+ DA+ K E+ ++P G
Sbjct: 149 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQG 208
Query: 301 SPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQR 360
TK Q R ++ P+ K+ D + P ++ + K+ ++ S
Sbjct: 209 EEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGE 268
Query: 361 TYSSSLKRS 369
+ LK +
Sbjct: 269 FMTHKLKHT 277
Score = 30.4 bits (67), Expect = 4.1
Identities = 64/346 (18%), Positives = 116/346 (33%), Gaps = 59/346 (17%)
Query: 5 RKDWSALSSLARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPS 64
+ DW A + ED+E++E E + R E R+ ++ P+
Sbjct: 174 KNDWRD----AEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDK-PT 228
Query: 65 VEEAEVPKPLPPASKDEDEDIQSILRTR----QERRQRRQVVEAAQAPIQERLEAEEGRN 120
++ E+ K+ E+++S + + + + Q + + + GR
Sbjct: 229 FKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRA 288
Query: 121 SLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVL 180
S+ +A P ++E R R +RG EE + ++ +E L
Sbjct: 289 SVDTKEAEGAP-----QVEAGKRLEELRRRRGETESEEFEKLKQKQQEA---------AL 334
Query: 181 EKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSE 240
E + KK + KVL E+ ++ A + R EK+ + E+
Sbjct: 335 ELEELKKKREERR-----------KVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR 383
Query: 241 KSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQP--LAQEPPAS 298
A ++ + E L+ +K P P E+ L + S
Sbjct: 384 AEAA------------EKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKS 431
Query: 299 GGSPATTK-----------EQRGRALPGKNLPSLAKQGASDPPTVA 333
G +T + EQ A+ G K ASD P A
Sbjct: 432 SGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPA 477
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 80.9 bits (198), Expect = 3e-15
Identities = 99/453 (21%), Positives = 172/453 (37%), Gaps = 42/453 (9%)
Query: 23 EEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDED 82
E+E + + ++ + E + ++ + P+ EEA+ P P A E
Sbjct: 513 EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP---PEAKSPEK 569
Query: 83 EDIQSILRTRQERRQRRQVVEAAQAPIQ----ERLEAEEGRNSLSPVQATQKPLVSKKEL 138
E+ +S + + + E A++P + E+ ++ + SP +A + P+ K+E
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEA-KSPV--KEEA 626
Query: 139 EIPPRRRLSREQRGPW---ALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKT-----A 190
+ P + + + P A E E EE K KSPV ++ P+K A
Sbjct: 627 KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA 686
Query: 191 PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKS--VLEKTSVSEKSLAPGMA 248
KS K+ + E+ + EK K V E+ S EK V E+ EK+ +P
Sbjct: 687 EAKSPEKAKSPVKEEAKSPEKA----KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSP--- 739
Query: 249 LGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQ 308
V E+A EKA + EK+ T D K + A E+ + + + KE+
Sbjct: 740 -------VKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEE 792
Query: 309 RGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKR 368
P AK + + P +VK P KEEE + + +
Sbjct: 793 -------VKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 369 SSPRTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKLERYHTAIRRSESVKSRGLPC 428
+P T K + E + K+ + EK + ++ E+ + +P
Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPT 905
Query: 429 TELFVAPVGVASKRHLFEKELAGQSRAEPASSR 461
E AP V K KE ++ EP ++
Sbjct: 906 PEK-EAPAKVEVKEDAKPKEKTEVAKKEPDDAK 937
Score = 64.7 bits (156), Expect = 2e-10
Identities = 77/317 (24%), Positives = 137/317 (43%), Gaps = 25/317 (7%)
Query: 15 ARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPL 74
A+ E+ + E+ + S ++P ++ D + S + P+ EEA P
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK-SPEAKTPAKEEARSPADK 780
Query: 75 PP--ASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPL 132
P A E+++S + + + E A+AP +E + EE + SPV+ +KP
Sbjct: 781 FPEKAKSPVKEEVKS------PEKAKSPLKEDAKAPEKEIPKKEEVK---SPVKEEEKP- 830
Query: 133 VSKKELEIPPRRRLSREQRGPWALE-EESLVGREPEERKKGVPEKSPVLEKSSMPKKTAP 191
+ +++ PP++ + E++ P + EE ++ E KK P+ P +E+ P P
Sbjct: 831 -QEVKVKEPPKK--AEEEKAPATPKTEEKKDSKKEEAPKKEAPK--PKVEEKKEPAVEKP 885
Query: 192 EKSLVSDKTSISE---KVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMA 248
++S V K +E KV EK + + K+ V E EK V +K K+ P
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEAPA-KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKP 944
Query: 249 LGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQ 308
+K + EKA E+ P +AK T S++P +P A +++ +Q
Sbjct: 945 AEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP--SKPKAEKAEKSSSTDQ 1002
Query: 309 RGRALPGKNLPSLAKQG 325
+ P K A +G
Sbjct: 1003 KDSKPPEKATEDKAAKG 1019
Score = 45.8 bits (107), Expect = 9e-05
Identities = 75/375 (20%), Positives = 139/375 (37%), Gaps = 49/375 (13%)
Query: 55 QASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLE 114
+ + E++ VE++E + +E + + + +E+ + + + + +E E
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTE-EEEKEAKEEEGKEEEGGEEEEAE 495
Query: 115 AEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVP 174
E P + P +KE + P + +EE+ + P E K
Sbjct: 496 GGEEETKSPPAEEAASP---EKEAKSPVKEEAKSPAEAKSPEKEEA---KSPAEVKSPEK 549
Query: 175 EKSPVLEKS-SMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVL 233
KSP E++ S P+ +PEK ++ +V + EK K E ++ +E KS
Sbjct: 550 AKSPAKEEAKSPPEAKSPEK----EEAKSPAEVKSPEKAKSPAK---EEAKSPAEAKS-- 600
Query: 234 EKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQ 293
EK+ +P V E+A K+ A KSP + +P + E+ +
Sbjct: 601 -----PEKAKSP----------VKEEA----KSPAEAKSPVKEEAKSPAEVKSPEKAKSP 641
Query: 294 EPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEAD 353
+ ++ A + S K A P S PV + K P K +
Sbjct: 642 TKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS---PVKAEAKSPEKAK--- 695
Query: 354 MSSPTQRTYSSSLKRSSP-----RTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKL 408
SP + S K SP ++ P KE ++T + +K + + +
Sbjct: 696 --SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP 753
Query: 409 ERYHTAIRRSESVKS 423
E+ T +S K+
Sbjct: 754 EKAKTLDVKSPEAKT 768
Score = 43.9 bits (102), Expect = 4e-04
Identities = 44/233 (18%), Positives = 102/233 (43%), Gaps = 17/233 (7%)
Query: 15 ARQRTLEDEEEQERERRRRHRNLSSTTDDEAPR-LSQNGDRQASASERLPSVEEAEVPKP 73
A+ ED + E+E ++ S ++E P+ + + + E+ P+ + E K
Sbjct: 799 AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKD 858
Query: 74 LPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQ-ERLEAEEGRNSLSPVQATQKPL 132
SK E+ + + + E ++ V + ++ ++ ++ EAE+ + +P + +
Sbjct: 859 ----SKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKV 914
Query: 133 VSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPE 192
K++ + + +++++ +E S +P E+K+ PEK E+ + K E
Sbjct: 915 EVKEDAKPKEKTEVAKKEPDDAKAKEPS----KPAEKKEAAPEKKDTKEEKA---KKPEE 967
Query: 193 KSLVSDKTSISEKVLASE----KTSLSEKIAVSEKRNSSEKKSVLEKTSVSEK 241
K K +K L+ E K +EK + +++++S + E + K
Sbjct: 968 KPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 80.9 bits (198), Expect = 3e-15
Identities = 112/530 (21%), Positives = 216/530 (40%), Gaps = 60/530 (11%)
Query: 14 LARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDR-QASASERLPSVEEAEVPK 72
+A QR +DEEE RERRRR R E L Q D+ + +A +P EEA+
Sbjct: 25 IAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPD-EEAKTTT 83
Query: 73 PLPPASKDEDEDIQSILRTRQERRQRR-------------QVVEAAQAPIQERLEAEEGR 119
D++ L R+ERRQ+R + +A+ + R++ +
Sbjct: 84 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 143
Query: 120 NSLSPVQATQKPLVSKKELEIPPRRRLSRE-QRGPWA-LEEESLVGREPEERKKGVPEKS 177
N + + +K ++ EI +++ Q+ W EE +E EE ++ P++
Sbjct: 144 NETT--EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 201
Query: 178 PV---------LEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNS-- 226
+ ++K PK+ KS + K +E V + ++ K+ +E S
Sbjct: 202 SIGENQIKDEKIKKDKEPKEEV--KSFMDRKKGFTE-VKSQNGEFMTHKLKHTENTFSRP 258
Query: 227 SEKKSVLEKTSVSEKSLAPGMALGSGRRLVSE-KASIFEKALASEKSPTADAKPAPKRAT 285
+ SV K + + G L RR E ++ FEK ++ + + K+
Sbjct: 259 GGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKRE 318
Query: 286 ASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKI 345
+ L +E +++R + + L ++ R + K+
Sbjct: 319 ERRKVLEEE-----------EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKM 367
Query: 346 PSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTV--- 402
P ++ +D P K +P+ S +++ + E ++ +S+ +K
Sbjct: 368 P-EDGLSDDKKP--------FKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVS 418
Query: 403 KLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEKELAGQSRAEPASSRK 462
K+ +LE+Y +AI ++S K ++L V GV + + ++EK S + K
Sbjct: 419 KIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNK 478
Query: 463 ENLRLSGVVTSRLNLWISRT---QESGDQDPQEAQKASSATERTQWGQKS 509
E L V+SR+N W+++T +S P + + +++R W ++S
Sbjct: 479 ETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQS 528
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 68.9 bits (167), Expect = 1e-11
Identities = 110/529 (20%), Positives = 216/529 (40%), Gaps = 49/529 (9%)
Query: 17 QRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASER-LPSVEEAEVPKPLP 75
+R + EE+ER + + + ++ DE R+ + +A+A ER EE E +
Sbjct: 268 ERARLEAEERERIKAEQDKKIA----DERARIE--AEEKAAAQERERREAEERERMREEE 321
Query: 76 PASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSK 135
+ +E + I+ + E RQR + E A ++R++ EE R + +A + +
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAE---EE 378
Query: 136 KELEIPPRRRLSREQRGPWALEEESLVGREPEERKKG--VPEK--------SPVLEKSSM 185
++ ++ ++R + + A++E + G + E++ +G V EK + VL+K
Sbjct: 379 EKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGE 438
Query: 186 PKKT---APEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKS 242
K T A + L DK + ++ + EK ++ K KK E S + +
Sbjct: 439 EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEF 498
Query: 243 LAPGM-------ALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQ-----P 290
+ + + GR V K + E A E + + T SE+
Sbjct: 499 MTHKLKHTENTFSRPGGRASVDTKEA--EGAPQVEAGKRLEELRRRRGETESEEFEKLKQ 556
Query: 291 LAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASD----PPTVASRLPPVTLQVKIP 346
QE +E+R + L + KQ +D RL + +
Sbjct: 557 KQQEAALELEELKKKREERRKVLEEEE--QRRKQEEADRKLREEEEKRRLKEEIERRRAE 614
Query: 347 SKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTV---K 403
+ E+ M K +P+ S +++ + E ++ +S+ +K K
Sbjct: 615 AAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSK 674
Query: 404 LGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEKELAGQSRAEPASSRKE 463
+ +LE+Y +AI ++S K ++L V GV + + ++EK S + KE
Sbjct: 675 IDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKE 734
Query: 464 NLRLSGVVTSRLNLWISRT---QESGDQDPQEAQKASSATERTQWGQKS 509
L V+SR+N W+++T +S P + + +++R W ++S
Sbjct: 735 TAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQS 783
Score = 63.2 bits (152), Expect = 6e-10
Identities = 76/331 (22%), Positives = 133/331 (40%), Gaps = 35/331 (10%)
Query: 14 LARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDR-QASASERLPSVEEAEVPK 72
+A QR +DEEE RERRRR R E L Q D+ + +A +P EEA+
Sbjct: 25 IAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPD-EEAKTTT 83
Query: 73 PLPPASKDEDEDIQSILRTRQERRQRR-------------QVVEAAQAPIQERLEAEEGR 119
D++ L R+ERRQ+R + +A+ + R++ +
Sbjct: 84 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 143
Query: 120 NSLSPVQATQKPLVSKKELEIPPRRRLSRE-QRGPWA-LEEESLVGREPEERKKGVPEKS 177
N + + +K ++ EI +++ Q+ W EE +E EE ++ P++
Sbjct: 144 NETT--EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 201
Query: 178 P---------VLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSE 228
V EK++ ++ SL + + S E E+ S++I+ EK +
Sbjct: 202 SIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEED 261
Query: 229 KKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASI--FEKALASEK-----SPTADAKPAP 281
K+ + + E + +++ E+A I EKA A E+ +
Sbjct: 262 KERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEE 321
Query: 282 KRATASEQPLAQEPPASGGSPATTKEQRGRA 312
KRA Q + +E + KE+ RA
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQRIKEEEKRA 352
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 66.2 bits (160), Expect = 7e-11
Identities = 98/434 (22%), Positives = 171/434 (39%), Gaps = 55/434 (12%)
Query: 23 EEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDED 82
E+E + ++ + ++ +AP + A A+ ++ + + A +S +D
Sbjct: 176 EDEPPKNQKPKITPVTVKAQTKAP------PKPARAAPKIANGKAASSSSSSSSSSSSDD 229
Query: 83 EDIQSILRTRQERRQRRQVV-----EAAQAPIQERLEAEEG------------RNSLSPV 125
+ + T ++ ++QVV +AA P ++ +E+ +N P
Sbjct: 230 SEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPY 289
Query: 126 QATQKPLVS--KKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKS 183
+ P KK L P ++ +Q+ + E+ S E +K P K+ V + +
Sbjct: 290 SSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKAT 349
Query: 184 SMP---KKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSE 240
+ P KK A S SD S SE K A + K NSS K +V K+ +
Sbjct: 350 TKPPPAKKAAESSSDSSDSDS-------SEDDEAPSKPAGTTK-NSSNKPAVTTKSPAVK 401
Query: 241 KSLAPGMALGSGRRLVSEKA---SIFEKALASEKSPT----ADAKPAPKRATASEQPLAQ 293
+ AP +G G++L++ KA S E++ +SE+ T A KP A P Q
Sbjct: 402 PAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQ 461
Query: 294 EPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEAD 353
P S S + + K S K+ P VA P K E ++
Sbjct: 462 APQGSRDSSSDSDSSSSEEEEEKTSKSAVKK---KPQKVAGGAAPSKPASAKKGKAESSN 518
Query: 354 MSSPTQRTYSSSLK---RSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKLER 410
SS + K + SPR + K N + LT + + K N+ + E+ ++
Sbjct: 519 SSSSDDSSEEEEEKLKGKGSPRP-----QAPKANGTSALT-AQNGKAAKNSEEEEEEKKK 572
Query: 411 YHTAIRRSESVKSR 424
+ +S S+K R
Sbjct: 573 AAVVVSKSGSLKKR 586
Score = 50.8 bits (120), Expect = 3e-06
Identities = 78/384 (20%), Positives = 150/384 (39%), Gaps = 35/384 (9%)
Query: 12 SSLARQRTLEDEEEQERERRRRHRNLSSTTDDEA--PRLSQNGDRQASASERLPSVEEAE 69
SS + + ++EEEQ++ + + SS A P+ S A E+ VE +E
Sbjct: 264 SSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSE 323
Query: 70 VPKPLPPASKDEDE--DIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQA 127
+S +E++ ++++ + + + + + +E+ P
Sbjct: 324 DSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGT 383
Query: 128 TQ----KPLVSKKELEIPPR----------RRLSREQRGPWALEEESLVGREPEERKKGV 173
T+ KP V+ K + P ++L + + EEES E + +K
Sbjct: 384 TKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVA 443
Query: 174 PEKSPVLEKS--SMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKS 231
K K+ S+P K AP+ S D +S S+ + E+ + K AV +K +
Sbjct: 444 TTKPKATAKAALSLPAKQAPQGS--RDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGA 501
Query: 232 VLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPL 291
K + ++K G A S + + E+ L + SP +P +A +
Sbjct: 502 APSKPASAKK----GKAESSNSSSSDDSSEEEEEKLKGKGSP----RPQAPKANGTSALT 553
Query: 292 AQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPS---- 347
AQ A+ S +E++ A+ SL K+ ++ A ++++ P+
Sbjct: 554 AQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPK 613
Query: 348 -KEEEADMSSPTQRTYSSSLKRSS 370
K+ E SSP +R ++ S
Sbjct: 614 RKKGEKRASSPFRRVREEEIEVDS 637
>gi|238624188 diffuse panbronchiolitis critical region 1 protein
[Homo sapiens]
Length = 1393
Score = 58.9 bits (141), Expect = 1e-08
Identities = 117/571 (20%), Positives = 191/571 (33%), Gaps = 103/571 (18%)
Query: 21 EDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASAS-------ERLPSVEEAEVPKP 73
E E ER + + R D+ S+S ER P E P P
Sbjct: 379 EPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSP 438
Query: 74 LPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLV 133
P +ER + P + R + +LSPV+ T+
Sbjct: 439 AEPTEN-------------RERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRET 485
Query: 134 SKKELEIP-PRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMP------ 186
+ E P P QR P+A E+ + EP E E++P+ +++ P
Sbjct: 486 TANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEH----GERTPLANENTTPSPAEPT 541
Query: 187 ---KKTAPEKSLVS--DKTSISEKV-LASEKT--SLSEKIA-------VSEKRNSS--EK 229
++TA EK+ S + T ++ LA+EKT SL+E +EK SS E
Sbjct: 542 ENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEP 601
Query: 230 KSVLEKTSVSEKSLAPGMALGSGRR---------------------LVSEKASIFEKALA 268
E+T ++ ++ P A + R +EK ++F
Sbjct: 602 TEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPT 661
Query: 269 SEKSPTADAK----PAPKRATASEQPLAQEPPASGG-------------------SPATT 305
+ TA+ K PA P A E S SPA
Sbjct: 662 ENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEP 721
Query: 306 KEQRGRALPGKNLPSLA-----KQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQR 360
E R R K P A ++ ++ T S P + P E+ S
Sbjct: 722 TENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPT 781
Query: 361 TYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKLERYHTAIRRSES 420
++ +T S +P + T L + P + E+ T +E
Sbjct: 782 ENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEP 841
Query: 421 VKSRGLPCTELFVA-PVGVASKRHLFEKELAGQSRAEPASSRKENLRLSGVVTSRLNLWI 479
++R E P R E S AEP E+ ++ + + L
Sbjct: 842 TENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPT----EHEEMTPLANEKTTLSP 897
Query: 480 SRTQESGDQDPQEAQKAS-SATERTQWGQKS 509
+ E+G++ P +K + S+ E T+ G+++
Sbjct: 898 AEPTENGERTPFTNEKTTPSSAEPTEHGERT 928
Score = 50.8 bits (120), Expect = 3e-06
Identities = 90/409 (22%), Positives = 155/409 (37%), Gaps = 61/409 (14%)
Query: 16 RQRTLEDEEE----QERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERL-PSVEE-AE 69
R+RT ++ + E R R N ++T P ++NGDR A+E+ PS+ E E
Sbjct: 725 RERTANEKTTPFPAEPTENRERTANENTTPSPAQP--TENGDRTPLANEKTTPSLAEPTE 782
Query: 70 VPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQ 129
K P A++ A ER + SP + T+
Sbjct: 783 NGKRTPFANEKTTSS------------------SAEPTEHAERTPLANENTTSSPAEPTE 824
Query: 130 --KPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPK 187
+ ++K + P +RE A E+ + EP E ++ ++ L + P
Sbjct: 825 NRERTANEKTTQFPAEPTENREST---ANEKTTPFPAEPTENREWTANENTTLSPAE-PT 880
Query: 188 KTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKR---NSSEKKSVLEKTSVSEKSLA 244
+ L ++KT++S +E T E+ + ++ +S+E E+T ++ +
Sbjct: 881 EHEEMTPLANEKTTLSP----AEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITT 936
Query: 245 PGMALGS--GRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQ----PLAQEPPAS 298
P A + G R+ +EKA+ T + P A +E PLA E +
Sbjct: 937 PSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANENTTT 996
Query: 299 GGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPT 358
SP + E R K PS A+ PT P + IPS + + T
Sbjct: 997 --SPTESTEHGERTANEKTTPSPAE------PTEHGERTPSANEKTIPSPAKPTEHEEMT 1048
Query: 359 QRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEK 407
S+ + ++P + KP + +TTL P+ + G K
Sbjct: 1049 P----SANENTTPSPV----KPTEHGEKTTLANEKITLSPEGPTEHGAK 1089
Score = 38.1 bits (87), Expect = 0.019
Identities = 74/423 (17%), Positives = 148/423 (34%), Gaps = 36/423 (8%)
Query: 108 PIQERLEAEEGRN-------SLSPVQAT--QKPLVSKKELEIPPRRRLS--REQRGPWAL 156
P E + +G++ S+ P +T K KK + P+ +++ + G +
Sbjct: 119 PTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTV 178
Query: 157 EEES-LVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLS 215
+S GR E+ + + S K++ + TS EK+ A+ KT+
Sbjct: 179 TRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYK 238
Query: 216 EKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTA 275
E + + ++ + + K+ S L S+ E ++
Sbjct: 239 TTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQ---SLAEPTEHGGRTANE 295
Query: 276 DAKPAPKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLA-----KQGASDPP 330
+ P+P T + + A E SPA E R R P A ++ ++
Sbjct: 296 NNTPSPAEPTENRERTANENTTL--SPAEPIENRERTANENTAPFPAGPTENREMTANEN 353
Query: 331 TVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLT 390
T P + ++ + PT+ ++ + ++P +P + T
Sbjct: 354 TTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSP----AEPTEHGERTPFA 409
Query: 391 RSASMKLPDNTVKLGEK--LERYHTAIRRSESVKSRGLPCTE-LFVAPVGVASKRHLFEK 447
+ + + GE+ L +T +E ++R E +P G R
Sbjct: 410 NDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTAN 469
Query: 448 ELAGQSRAEPASSRKENLRLSGVVTSRLNLWISRTQESGDQDPQEAQK-ASSATERTQWG 506
E S EP +R+ + + E+G + P +K SS+ E T+ G
Sbjct: 470 EKTTLSPVEPTENRET------TANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHG 523
Query: 507 QKS 509
+++
Sbjct: 524 ERT 526
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 56.6 bits (135), Expect = 5e-08
Identities = 77/319 (24%), Positives = 134/319 (42%), Gaps = 29/319 (9%)
Query: 46 PRLSQNGDRQASASERLPSVEE--AEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVE 103
P ++ +A A P+VEE A+V +PL P +E + L T E E
Sbjct: 398 PLPAEGALEEAPAKVEPPTVEETLADV-QPLLPEEAPREEARELQLSTAMETPAEEAPTE 456
Query: 104 AAQAPIQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVG 163
Q+P+ + AEE + + AT+ PP E R P L EE+
Sbjct: 457 F-QSPLPKETTAEEASAEIQLLAATE-----------PPADETPAEARSP--LSEETSAE 502
Query: 164 REPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEK 223
E + + E++ E S+ + A ++ +D+T + SE+TS E A +E
Sbjct: 503 EAHAEVQSPLAEETTAEEASAEIQLLAAIEA-PADETPAEAQSPLSEETSAEE--APAEV 559
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKR 283
++ S K +E+ + L P SG +E+AS + LA+ ++ +A +
Sbjct: 560 QSPSAKGVSIEEAPLE---LQPP----SGEETTAEEASAAIQLLAATEASAEEAPAEVQP 612
Query: 284 ATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQV 343
A E P +PP + +PA + P + P A++ ++ + P +Q
Sbjct: 613 PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 672
Query: 344 KIPSKEEEADMSS-PTQRT 361
P++E A++ S P + T
Sbjct: 673 P-PAEEAPAEVQSLPAEET 690
Score = 41.6 bits (96), Expect = 0.002
Identities = 78/349 (22%), Positives = 127/349 (36%), Gaps = 40/349 (11%)
Query: 17 QRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPP 76
Q L +E +E R + T +EAP Q+ + + +E S E + PP
Sbjct: 425 QPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEA-SAEIQLLAATEPP 483
Query: 77 ASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKK 136
A DE E + Q+P+ E AEE + + A + P
Sbjct: 484 A----DETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAP---AD 536
Query: 137 ELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLV 196
E + LS E + EE + P + + E L+ S + TA E
Sbjct: 537 ETPAEAQSPLSEET----SAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEE---- 588
Query: 197 SDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLV 256
S + ++LA+ + S E A + + E + ++ E AP
Sbjct: 589 ---ASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEE---AP----------A 632
Query: 257 SEKASIFEKALASEKSPTADAKPAP-KRATASEQPLAQEPPASGGSPATTKEQRGRALP- 314
+ E+A A + P A+ PA + A E P +PP + +PA + P
Sbjct: 633 EVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPI 692
Query: 315 GKNLPSLAKQGASDPP----TVASRLPPVTLQV--KIPSKEEEADMSSP 357
+ L ++ A D P +V PP L + + P E A++S P
Sbjct: 693 EETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPP 741
Score = 36.6 bits (83), Expect = 0.057
Identities = 43/234 (18%), Positives = 83/234 (35%), Gaps = 22/234 (9%)
Query: 138 LEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVS 197
+ IPP ++ +EQ+ ++ E ++ R P+ S K K + K S
Sbjct: 143 MNIPPVEKVDKEQQTYFSESEIVVISR---------PDSSSTKSKEDALKHKSSGKIFAS 193
Query: 198 DKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVS 257
+ ++E+ S + + + VL + + E+ P + GS + V+
Sbjct: 194 EHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVA 253
Query: 258 EKA----------SIFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKE 307
+ + L E + A+ +PA + + + P A +
Sbjct: 254 SAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENS 313
Query: 308 QRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKI--PSKEEEADMSSPTQ 359
+ + P + P + PP+ A P V L +I PS EE P +
Sbjct: 314 VKVQPPPAEEAPLVEFPAEIQPPS-AEESPSVELLAEILPPSAEESPSEEPPAE 366
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 55.8 bits (133), Expect = 9e-08
Identities = 95/420 (22%), Positives = 153/420 (36%), Gaps = 67/420 (15%)
Query: 5 RKDWSALS-SLARQRTL--------EDEEEQERERRRRHRNLSSTTDDEAPR-----LSQ 50
R D S L+ S+ R+R L E EE+Q +R L D+ A R L++
Sbjct: 18 RPDLSTLTHSIVRRRYLAHSGRSHLEPEEKQALKRLVEEELLKMQVDEAASREDKLDLTK 77
Query: 51 NGDRQASA-----------SERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRR 99
G R + + S EA P P +K+ S + RR +
Sbjct: 78 KGKRPPTPCSDPERKRFRFNSESESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASK 137
Query: 100 QVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKKEL---EIPPRRRLSREQRGPWAL 156
V E++ Q L A+ G S + K KK + + P + +SR+Q
Sbjct: 138 AVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQ------ 191
Query: 157 EEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSE 216
RE E E PV + + KSL + E++LA +K E
Sbjct: 192 ------AREESEES----EAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQREE 241
Query: 217 KIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTAD 276
++ EK EK +T + + R+ E+ S +K+ A +D
Sbjct: 242 EVEEEEKEEDEEKGDWKPRTRSNGR-----------RKSAREERSCKQKSQAKRLLGDSD 290
Query: 277 AKPAPKRATAS--EQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVAS 334
++ K A +S + +EPP S T+ + G+ L G + G +P S
Sbjct: 291 SEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSS-EDEEDSGKGEPTAKGS 349
Query: 335 RLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSAS 394
R K+ + S +R S S P+ + + K++S TRS+S
Sbjct: 350 R--------KMARLGSTSGEESDLEREVSDSEAGGGPQG-ERKNRSSKKSSRKGRTRSSS 400
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 55.1 bits (131), Expect = 2e-07
Identities = 93/424 (21%), Positives = 149/424 (35%), Gaps = 55/424 (12%)
Query: 16 RQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLP 75
R+R+ E R+ R R+ S+++ E R R PSV P+P
Sbjct: 1687 RRRSSRSSPELTRKARLSRRSRSASSSPETR------SRTPPRHRRSPSVSS---PEPAE 1737
Query: 76 PASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK----- 130
+ S RT+ R+ R + +P L+ R+ + T++
Sbjct: 1738 KSRSSRRRRSASSPRTKTTSRRGR-----SPSPKPRGLQRSRSRSRREKTRTTRRRDRSG 1792
Query: 131 --PLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEE----RKKGVPEKSPVLEKSS 184
S++ R R++R +RG S +E R++G P K S
Sbjct: 1793 SSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRS 1852
Query: 185 MPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLA 244
+T+P K S S A+ + S S +S +R+ S V + S S S+
Sbjct: 1853 R-SRTSPAPW----KRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVT 1907
Query: 245 PGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGGSPAT 304
RR +AS + + ++P P +R + S P + S P T
Sbjct: 1908 --------RRRSRSRASPVSRRRSRSRTP-----PVTRRRSRSRTPTTRRRSRSRTPPVT 1954
Query: 305 TKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVT-----LQVKIPSKEEEADMSSPTQ 359
+ R R P S ++ SR PVT + ++ +SP
Sbjct: 1955 RRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVT 2014
Query: 360 RTYSSS------LKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKLERYHT 413
R S S +RS RT K + S + R + + P T + L R
Sbjct: 2015 RRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP-RTARGKRSLTRSPP 2073
Query: 414 AIRR 417
AIRR
Sbjct: 2074 AIRR 2077
Score = 47.8 bits (112), Expect = 2e-05
Identities = 91/427 (21%), Positives = 142/427 (33%), Gaps = 52/427 (12%)
Query: 31 RRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILR 90
+R S+ D + + G R S S + V+ P P + D S +
Sbjct: 1513 QRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVK----PSASPQERSESDSSPDSKAK 1568
Query: 91 TRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLV---------SKKELEIP 141
TR RQR + + + + RL R+ SP + KP S E + P
Sbjct: 1569 TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSP-EVKDKPRAAPRAQSGSDSSPEPKAP 1627
Query: 142 PRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTS 201
R L R R S GR P E SP S +TA S S +
Sbjct: 1628 APRALPRRSR-----SGSSSKGRGPSPEGSSSTESSPEHPPKS---RTARRGSRSSPEPK 1679
Query: 202 ISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKAS 261
+ ++S S + R S +S +S +S P R S S
Sbjct: 1680 TKSRTPPRRRSSRSSPELTRKARLSRRSRSA--SSSPETRSRTP------PRHRRSPSVS 1731
Query: 262 IFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASG---------GSPATTKEQRGRA 312
E A S S + +P+ T S + + P G T +R R+
Sbjct: 1732 SPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRS 1791
Query: 313 LPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQ----RTYSSSLKR 368
++ ++ S R + P+++E + SS + RT +S KR
Sbjct: 1792 GSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKR 1851
Query: 369 SSPRTISFRMKPKKENSETTLTRSASMKLP--------DNTVKLGEKLERYHTAIRRSES 420
S RT K + + R + + P T + + R T++ R S
Sbjct: 1852 SRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRS 1911
Query: 421 VKSRGLP 427
+SR P
Sbjct: 1912 -RSRASP 1917
Score = 44.7 bits (104), Expect = 2e-04
Identities = 83/396 (20%), Positives = 130/396 (32%), Gaps = 36/396 (9%)
Query: 26 QERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDED--- 82
+ R R R S T S+ R+ + R P+ + P+ S+
Sbjct: 583 RSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPAR 642
Query: 83 EDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKKELEIPP 142
+S RT R + R A + + R A S S A + S+ P
Sbjct: 643 RSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRT-----P 697
Query: 143 RRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSI 202
RR SR + + R P+ R + + + +++ S K+ I
Sbjct: 698 RRGRSRSRS---LVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754
Query: 203 SEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASI 262
S + SLS + ++ R S + +KS P SG K+
Sbjct: 755 SSR----RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRT 810
Query: 263 FEKALASEKSPTADAK---------------PAPKRATASEQPLAQEPPASGGSPATTKE 307
+ S SP K P K T Q P A+ S +
Sbjct: 811 PPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRR 870
Query: 308 QRGRALPGKNL----PSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEAD-MSSPTQRTY 362
+ P L PS S PP V S PP + S + + + SP QR++
Sbjct: 871 SCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSH 930
Query: 363 SSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLP 398
S S SP ++ R P++ S + + S LP
Sbjct: 931 SGS-SSPSPSRVTSRTTPRRSRSVSPCSNVESRLLP 965
Score = 39.3 bits (90), Expect = 0.009
Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 11/185 (5%)
Query: 194 SLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGR 253
+L S + +S S +TS + R+ + + + SE++ +P +G
Sbjct: 2379 NLTSPRVPLSAYERVSGRTSPP---LLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQ-- 2433
Query: 254 RLVSEKASIFEKALASEKSPTADAKPAPKRAT-ASEQPLAQEPPASGGSPATTKEQRG-- 310
+ S+ A +SP A R A P+A S G+ ATT G
Sbjct: 2434 ---APSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDH 2490
Query: 311 RALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKRSS 370
+ P + +PP P L P+KE + SS + + SSS SS
Sbjct: 2491 NGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS 2550
Query: 371 PRTIS 375
+ S
Sbjct: 2551 SSSSS 2555
Score = 35.8 bits (81), Expect = 0.097
Identities = 69/357 (19%), Positives = 119/357 (33%), Gaps = 31/357 (8%)
Query: 35 RNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQE 94
RNLS R G+ E L +E A V +P P E + + E
Sbjct: 21 RNLSLVRGRRGERPDYKGE------EELRRLEAALVKRPNPDILDHERKRRVELRCLELE 74
Query: 95 RRQRRQVVEAAQAPIQERL----------EAEEGRNSLSPVQATQKPLVSKKELEIPPRR 144
Q E Q IQE++ + G +P Q+P V++
Sbjct: 75 EMMEEQGYEEQQ--IQEKVATFRLMLLEKDVNPGGKEETP---GQRPAVTETHQLAELNE 129
Query: 145 RLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISE 204
+ + R + + + + G + +++ K P E S S +
Sbjct: 130 KKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKK 189
Query: 205 KVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFE 264
K ++ SE + +R S KK S S+K S R+ +K
Sbjct: 190 KKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSR 249
Query: 265 KALASEKSPTADAKPAPKRATASEQPLAQEPPAS---------GGSPATTKEQRGRALPG 315
+ KS A + A++S+ ++ A+ G SP+ +RG
Sbjct: 250 STTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAP 309
Query: 316 KNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEE-ADMSSPTQRTYSSSLKRSSP 371
+ P P A++ P + K K+E+ A SP+ S+ + +P
Sbjct: 310 FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAP 366
Score = 35.8 bits (81), Expect = 0.097
Identities = 106/478 (22%), Positives = 177/478 (37%), Gaps = 59/478 (12%)
Query: 5 RKDWSALSSLARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPS 64
RK+ S S + E ++ R RR R+LSS RLS R S S P
Sbjct: 730 RKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR--RSLSGSSPCPK 787
Query: 65 VEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQE-RLEAEEGRNSLS 123
K P + Q ++R R+ R ++ P Q+ + + + +S S
Sbjct: 788 ------QKSQTPPRRSRSGSSQPKAKSRTPPRRSRS--SSSPPPKQKSKTPSRQSHSSSS 839
Query: 124 P---VQATQKPLVSK------KELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVP 174
P V++ P E + P+RR E + + L R P +
Sbjct: 840 PHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE-----SSPDPELKSRTPS--RHSCS 892
Query: 175 EKSPVLEKSSMPKKTAPEKSLVSD---KTSISEKVLASEKTSLSEKIAVSEKRNSSEKKS 231
SP KSS P + +P +S K IS + + +S V+ + +S
Sbjct: 893 GSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952
Query: 232 VLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPL 291
V ++V + L GS S + + +S + P PK
Sbjct: 953 VSPCSNVESRLLPRYSHSGS-----SSPDTKVKPETPPRQSHSGSISPYPK-------VK 1000
Query: 292 AQEP--PASGGSPATTKEQRGRALPGKNLP---SLAKQGASDPPTVASRLPPVTLQVKIP 346
AQ P P+ GS + +++ + ++ P SL S P S +LQ+K
Sbjct: 1001 AQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQ 1060
Query: 347 SKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENS-ETTLTRSASMKLPDNTVKLG 405
S+ +SP R+ +SS + + S ++ K + S + +RS+S P +
Sbjct: 1061 SQ------TSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSS---PVTELASR 1111
Query: 406 EKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEKELAGQSRAEPASSRKE 463
+ + S +KS P F + +S + L GQSR E A S+++
Sbjct: 1112 SPIRQDRGEFSASPMLKSGMSPEQSRFQS--DSSSYPTVDSNSLLGQSRLETAESKEK 1167
Score = 33.9 bits (76), Expect = 0.37
Identities = 40/175 (22%), Positives = 67/175 (38%), Gaps = 28/175 (16%)
Query: 38 SSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQ 97
SS++ + S + D + S+ P V VP P PA K+ + + T +R++
Sbjct: 2547 SSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP-TPAPKEAVREGRPPEPTPAKRKR 2605
Query: 98 RRQVVEAAQAPIQERLEAEEGRNSLSP-----------------------VQATQKPLVS 134
R ++ + + +S S QA KP
Sbjct: 2606 RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASP 2665
Query: 135 KKELEIPPRRRLSREQRGPW-ALEEESLVGREPEERKKGVPEKSPVLEKSSMPKK 188
KK PP R SR R P +L + + P ER++ P+ SP ++SS ++
Sbjct: 2666 KKP---PPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSER 2717
Score = 33.5 bits (75), Expect = 0.48
Identities = 52/268 (19%), Positives = 92/268 (34%), Gaps = 32/268 (11%)
Query: 141 PPRRRLSREQRGPWALEEESLVGRE---PEERKKGVPEKSPVLEKSSMPKKTAPEKSLVS 197
PP +R + P A + + P R P +S + P+ P
Sbjct: 2399 PPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQ 2458
Query: 198 DKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVS 257
+ I++ + SLS + ++ + +L APG+ V
Sbjct: 2459 SRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP-------APGVPHSD----VG 2507
Query: 258 EKASIFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKN 317
E + A + S A +PA +R ++S + +S S +++ G +
Sbjct: 2508 EPPA---STGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
Query: 318 LPSLAKQGASDPPTVASRLPPVTLQVK-----------IPSKEEEADMSSPTQRTYSSSL 366
SL Q P R+P T K P+K + SS + + SSS
Sbjct: 2565 GSSLPVQ----PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSS 2620
Query: 367 KRSSPRTISFRMKPKKENSETTLTRSAS 394
SS + S +S ++ + S+S
Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Score = 32.3 bits (72), Expect = 1.1
Identities = 55/276 (19%), Positives = 92/276 (33%), Gaps = 41/276 (14%)
Query: 45 APRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEA 104
A S GD S P V ++V +P PAS + S L Q ++RR +
Sbjct: 2481 ATTTSSAGDHNGMLSVPAPGVPHSDVGEP--PASTGAQQP--SALAALQPAKERRSSSSS 2536
Query: 105 AQAPIQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGR 164
+ + + +S S ++ E S +
Sbjct: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSD--------------------------SEGSSLPV 2570
Query: 165 EPEERKKGVPEKSPVLE---KSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVS 221
+PE K VP +P + + P + P K +S S +S +S S + S
Sbjct: 2571 QPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
Query: 222 EKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPA- 280
+SS S +S S PG + +K E+ S + P + +
Sbjct: 2631 SSSSSSSSSSSSSSSSSSPSPAKPG-PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSR 2689
Query: 281 ------PKRATASEQPLAQEPPASGGSPATTKEQRG 310
+R S QP ++ +S + + QRG
Sbjct: 2690 SLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRG 2725
Score = 32.0 bits (71), Expect = 1.4
Identities = 43/178 (24%), Positives = 67/178 (37%), Gaps = 28/178 (15%)
Query: 208 ASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIF---E 264
A + ++L+ E+R+SS S +S S S + + GS SE +S+ E
Sbjct: 2515 AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS-DSEGSSLPVQPE 2573
Query: 265 KALASEKSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQ 324
AL SPT PAPK A +P P T +R R + S +
Sbjct: 2574 VALKRVPSPT----PAPKEAVREGRP-----------PEPTPAKRKRRSSSSSSSSSSSS 2618
Query: 325 GASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKK 382
+S + +S S + SS + + S S + P+ + PKK
Sbjct: 2619 SSSSSSSSSS---------SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK 2667
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 54.3 bits (129), Expect = 3e-07
Identities = 89/372 (23%), Positives = 141/372 (37%), Gaps = 76/372 (20%)
Query: 21 EDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLP-------SVEEAEVP-- 71
E+ EE+E ER H + + P + + + P +V E +VP
Sbjct: 9769 EEYEEREYERYEEHEEYITEPEKPIP-VKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVP 9827
Query: 72 -----KPLPPASKDEDEDI-QSILRTRQERRQRRQVVE-AAQAPIQ-ERLEAEEG----- 118
KP PP +E + + + +R +R++ QV E AA+ P++ +R+ AEE
Sbjct: 9828 IPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPR 9887
Query: 119 RNSLSPVQATQKPL------VSKKELEIPPRRRLSREQRGPWALEEESLVGRE------- 165
+ PV+ + P V+ +E + E+ + EEE + E
Sbjct: 9888 KEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIP 9947
Query: 166 ---PEERKKGVPEKS---PVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIA 219
PE +K VPE+ PV +K P PE V K VL +K
Sbjct: 9948 VKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPE---VPKKPEEKVPVLIPKK-------- 9996
Query: 220 VSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKP 279
EK ++ V +K EK P V +K K P KP
Sbjct: 9997 --EKPPPAKVPEVPKKPVPEEKVPVP----------VPKKVEA-----PPAKVPEVPKKP 10039
Query: 280 APKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPS-LAKQGASDPPTVASRLPP 338
P++ P E P PA E + +P + P+ + K+ + PP V + P
Sbjct: 10040 VPEKKVPVPAPKKVEAP-----PAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREP 10094
Query: 339 VTLQVKIPSKEE 350
V + V +P +EE
Sbjct: 10095 VPVPVALPQEEE 10106
Score = 53.5 bits (127), Expect = 4e-07
Identities = 79/338 (23%), Positives = 123/338 (36%), Gaps = 66/338 (19%)
Query: 60 ERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEG- 118
E +P + A KP P +K + + +L E + V E A++P E E E
Sbjct: 10755 EVVPEKKVAVPKKPEVPPAKVPEVPKKPVL----EEKPAVPVPERAESPPPEVYEEPEEI 10810
Query: 119 --RNSLSPVQATQKPLVSKKELEIPPR------RRLSREQRGPWALEEESLVGREPEERK 170
++P + P+ ++E E+PP +++ E++ P + E+ +EPE K
Sbjct: 10811 APEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEK 10870
Query: 171 --------------KGVPEKSPVLEK----SSMPKKTAPEKSLVSDKTSISE-KVLASEK 211
P K V EK ++PKK PEK V +K ++ KV EK
Sbjct: 10871 VIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEK 10930
Query: 212 TSLSEKIAVSEKRNSSEK---KSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALA 268
K+ K E+ KSVL K R E+ + K L
Sbjct: 10931 K--VRKLLPERKPEPKEEVVLKSVLRK------------------RPEEEEPKVEPKKLE 10970
Query: 269 SEKSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPS-------L 321
K P P PK E P + P E + P LP+
Sbjct: 10971 KVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIK----PAIPLPAPEPKPKPE 11026
Query: 322 AKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQ 359
A+ PP V P+ V +P ++A+ +P +
Sbjct: 11027 AEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKE 11064
Score = 47.0 bits (110), Expect = 4e-05
Identities = 72/301 (23%), Positives = 115/301 (38%), Gaps = 26/301 (8%)
Query: 60 ERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGR 119
E +P EE E + + E +++ ++ Q R + VE I E EAEE
Sbjct: 10375 EEIP--EEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVI-EVFEAEEVE 10431
Query: 120 NSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKK-GVPEKSP 178
P + P +S+K IPP++ ++ + + + PE KK V EK
Sbjct: 10432 VFEKPKAPPKGPEISEKI--IPPKKPPTK------VVPRKEPPAKVPEVPKKIVVEEKVR 10483
Query: 179 VLEKSSMPKKTAPEKSLVSDKTSISEKVL----ASEKTSLSEKIAVSEKRNSSEKKSVLE 234
V E+ +P PE ++ K + EK + A + + K+ + K EKK +
Sbjct: 10484 VPEEPRVPPTKVPE--VLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVP 10541
Query: 235 KTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQE 294
E + P + V EK + E +SP + APK ++ A
Sbjct: 10542 PPKKPE--VPPTKVPEVPKAAVPEK-KVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAP 10598
Query: 295 PPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVK-----IPSKE 349
P +P E +P K +P + PPT +P V + K IP K
Sbjct: 10599 PKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKP 10658
Query: 350 E 350
E
Sbjct: 10659 E 10659
Score = 37.7 bits (86), Expect = 0.025
Identities = 50/235 (21%), Positives = 94/235 (40%), Gaps = 28/235 (11%)
Query: 78 SKDEDEDIQSILRTRQERRQRRQVVEAAQAPI---------QERLEAEEGRNSLSPVQAT 128
S E+E+ SI R+E R+ + E + + +E+L R P + T
Sbjct: 9496 SYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVT 9555
Query: 129 Q--------KPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVL 180
+ KP + K E PP ++ P + E V +++K P K P
Sbjct: 9556 ERQEKKIVLKPKIPAKIEEPPP----AKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEE 9611
Query: 181 EKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVS-EKRNSSEKKSVLE--KTS 237
K +P+K P K + ++ ++ + + EK+ V+ K+ + K V E K +
Sbjct: 9612 PKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRA 9671
Query: 238 VSEK---SLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQ 289
V E+ L P ++ + + ++ S ++P + +P K T E+
Sbjct: 9672 VPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPI-KEVTIMEE 9725
Score = 35.8 bits (81), Expect = 0.097
Identities = 90/469 (19%), Positives = 171/469 (36%), Gaps = 84/469 (17%)
Query: 21 EDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKD 80
E +E+ E + + + +++ + +R+ E EEA + + K+
Sbjct: 9096 EPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKE 9155
Query: 81 E-DEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKK--- 136
+E + + + ++ + + P+ E++E R VQ T+ P VSKK
Sbjct: 9156 VYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVP 9215
Query: 137 -------------ELEIP----PRRRLSREQRGPWALEEESLVGREPEERKKGVPEK--- 176
E+++P + +S E+ + EE + PE +K+ V E+
Sbjct: 9216 QKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIH 9275
Query: 177 -------SPVLEKSSMPKKTAPEKSL-----------VSDKTSISEKVLASEKTSL---S 215
P + +P+K APE+ + +K + EK +
Sbjct: 9276 VAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPK 9335
Query: 216 EKIAVSEKRNSSEKKSVLEK---TSVSEKSLAPGMALGSGRR--LVSEKASIFEKALASE 270
++ A K KK V E+ V++K AP + ++ + EK +I + E
Sbjct: 9336 KEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQ---RE 9392
Query: 271 KSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPP 330
+SP PK+ E+ P + ALP K +P ++ + P
Sbjct: 9393 ESPPPAVPEIPKKKVPEER-----KPVPRKEEEVPPPPKVPALPKKPVP---EEKVAVPV 9444
Query: 331 TVASRLPPVTLQVK-------------------IPSKEEEADMSSPTQRTYSSSLKRSSP 371
VA + PP +V +P + E + +S S +
Sbjct: 9445 PVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGV 9504
Query: 372 RTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKLERYHTAIRRSES 420
+R + ++E E +T M+ P+ V + EKL H +R E+
Sbjct: 9505 SISVYREEEREEEEEAEVTEYEVMEEPEEYV-VEEKL---HIISKRVEA 9549
Score = 35.8 bits (81), Expect = 0.097
Identities = 74/369 (20%), Positives = 142/369 (38%), Gaps = 59/369 (15%)
Query: 23 EEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKD-- 80
EE +E + +S + E +++ +++ ++P+ E P +P A K
Sbjct: 9529 EEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIV 9588
Query: 81 EDEDIQSILRTRQERRQRRQVVEAAQAPIQER------LEAEE---GRNSLSPVQATQ-- 129
++ + + + ++E+ +V E + P+ E+ ++ EE + + +Q TQ
Sbjct: 9589 PEKKVPAPV-PKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEE 9647
Query: 130 KPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEK-----SPVLEKSS 184
K LV+ + E PP+ R+ PEE K+ VPE+ P E+
Sbjct: 9648 KVLVAVTKKEAPPKARV-------------------PEEPKRAVPEEKVLKLKPKREEEP 9688
Query: 185 MPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNS----SEKKSVLEKTSVSE 240
K T K +V ++ +S + E + E + EK + E SV + E
Sbjct: 9689 PAKVTEFRKRVVKEE-KVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEE 9747
Query: 241 ------KSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQE 294
K + + +E+ E+ T KP P + E+P+ +
Sbjct: 9748 YEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVK-PVPEEPVPTK 9806
Query: 295 PPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIP---SKEEE 351
P A PA + +A+P + +P + PP P + KI +K E+
Sbjct: 9807 PKA---PPAKVLK---KAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREK 9860
Query: 352 ADMSSPTQR 360
++ P +
Sbjct: 9861 EQVTEPAAK 9869
Score = 35.0 bits (79), Expect = 0.16
Identities = 66/313 (21%), Positives = 120/313 (38%), Gaps = 25/313 (7%)
Query: 62 LPSVEEAEVPKPLPPASKDE--DEDIQSILRTRQERRQRRQVVEAAQAPIQERL--EAEE 117
+P ++ E P P P + E E + ++ +V E +A + E+ EA
Sbjct: 10512 VPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIP 10571
Query: 118 GRNSLSPVQATQKP---LVSKKELEIPPRRRLSREQRGPWALEE---ESLVGREPEERKK 171
+ P + + P + KK PP++ + P A +E E V P ++ +
Sbjct: 10572 PKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPE 10631
Query: 172 GVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIA--VSEKRNSS-- 227
P K P + K ++P+K PE ++ E E+ +L E A V E ++
Sbjct: 10632 VPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPP 10691
Query: 228 -----EKKSVLEKTS---VSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKP 279
KK V EK + V++K P + + + V + + ++P A
Sbjct: 10692 QVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPE 10751
Query: 280 APKRATASEQPLAQEPPASGGSPATTKE-QRGRALPGKNLPSLAKQGASDPPTVASRLPP 338
PK ++ + P PA E + L K + ++ S PP V
Sbjct: 10752 VPKEVVPEKKVAVPKKPEV--PPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEE 10809
Query: 339 VTLQVKIPSKEEE 351
+ + +I +EE+
Sbjct: 10810 IAPEEEIAPEEEK 10822
Score = 33.9 bits (76), Expect = 0.37
Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 13/141 (9%)
Query: 119 RNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSP 178
+NS V ++ K + K ++ +++S ++ +++++V E + +K+
Sbjct: 32927 KNSAGSVSSSCKLTI--KAIKDTEAQKVSTQKTSEITPQKKAVVQEE-------ISQKAL 32977
Query: 179 VLEKSSMPKKTAPEKSLVSDKTS---ISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEK 235
E+ M + + EK + ++ S ISE+V S TSL EK V E+ + + S +
Sbjct: 32978 RSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSL-EKSIVHEEITKTSQASEEVR 33036
Query: 236 TSVSEKSLAPGMALGSGRRLV 256
T K+ + M++ G+RLV
Sbjct: 33037 THAEIKAFSTQMSINEGQRLV 33057
Score = 30.0 bits (66), Expect = 5.3
Identities = 36/169 (21%), Positives = 66/169 (39%), Gaps = 10/169 (5%)
Query: 81 EDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKKELEI 140
+DE + S++ + R + R E + +LE + S V P+ + EI
Sbjct: 8898 DDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEI 8957
Query: 141 P-------PRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEK 193
P P + E++ P E ++ KK V + + + + KK P
Sbjct: 8958 PPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPT 9017
Query: 194 SLVSDKTSISEKVLASEKTSLSEKIAVSEKRN-SSEKKSVLEKTSVSEK 241
+L+ K E + S K + + ++ K+ EK++V EK K
Sbjct: 9018 TLIPAKA--PEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHK 9064
Score = 29.3 bits (64), Expect = 9.0
Identities = 47/250 (18%), Positives = 95/250 (38%), Gaps = 23/250 (9%)
Query: 61 RLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRN 120
R+P ++ P P A+K + QS R R V +P+ R + R
Sbjct: 256 RIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPV--RSVSPAARI 313
Query: 121 SLSPVQATQKPLVSKKEL--------EIPP--------RRRLSREQRGPWALEEESLVGR 164
S SP+++ + PL+ +K E+PP E R +
Sbjct: 314 STSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVASSSEAEMRETTLTTSTQIRTE 373
Query: 165 EPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVL---ASEKTSLSEKIAVS 221
E E + GV E+ + + + S ++ + K + A + +++ +A
Sbjct: 374 ERWEGRYGVQEQVTISGAAGAAASVSASASYAAEAVATGAKEVKQDADKSAAVATVVAAV 433
Query: 222 EKRNSSEKK-SVLEKTSVSEKSLAPGMALGSGR-RLVSEKASIFEKALASEKSPTADAKP 279
+ E S +E+T+ + A + + R +EK ++ + +A++K+ + K
Sbjct: 434 DMARVREPVISAVEQTAQRTTTTAVHIQPAQEQVRKEAEKTAVTKVVVAADKAKEQELKS 493
Query: 280 APKRATASEQ 289
K ++Q
Sbjct: 494 RTKEVITTKQ 503
Score = 29.3 bits (64), Expect = 9.0
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 210 EKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPG 246
E T+++EK EKR + V+ TS++E+ PG
Sbjct: 1041 ETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPG 1077
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 53.5 bits (127), Expect = 4e-07
Identities = 93/461 (20%), Positives = 165/461 (35%), Gaps = 62/461 (13%)
Query: 21 EDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASAS-------ERLPSVEEAEVPKP 73
E E ER + + R D+ S+S ER P E P P
Sbjct: 441 EPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSP 500
Query: 74 LPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLV 133
P +ER + P + R + +LSPV+ T+
Sbjct: 501 AEPTEN-------------RERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRET 547
Query: 134 SKKELEIP-PRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMP------ 186
+ E P P QR P+A E+ + EP E E++P+ +++ P
Sbjct: 548 TANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEH----GERTPLANENTTPSPAEPT 603
Query: 187 ---KKTAPEKSLVS--DKTSISEKV-LASEKT--SLSEKIAVSEKRNSSEKKSVLEKTSV 238
++TA EK+ S + T ++ LA+EKT SL+E ++ + +K+
Sbjct: 604 ENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEP 663
Query: 239 SEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQEPPAS 298
+E +A + +E E+ A+E + + A P R + + P
Sbjct: 664 TEHEERTPLANENTTPSPAEPTENRERT-ANENTTPSPAGPTENREMTANEKTTLFPAEP 722
Query: 299 GGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMS--S 356
+ T ++ + P + + + ++ T +S P + P E +S
Sbjct: 723 TENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAG 782
Query: 357 PTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKLERYHTAIR 416
PT+ ++ ++++P F +P EN E T + + P + G++ T +
Sbjct: 783 PTENRERTANEKTTP----FPAEP-TENRERTANENTTPS-PAQPTENGDR-----TPLA 831
Query: 417 RSESVKSRGLPCTELFVAPVGVASKRHLFEKELAGQSRAEP 457
++ S P KR F E S AEP
Sbjct: 832 NEKTTPSLAEPTEN---------GKRTPFANEKTTSSSAEP 863
Score = 38.9 bits (89), Expect = 0.011
Identities = 74/423 (17%), Positives = 148/423 (34%), Gaps = 36/423 (8%)
Query: 108 PIQERLEAEEGRN-------SLSPVQAT--QKPLVSKKELEIPPRRRLS--REQRGPWAL 156
P E + +G++ S+ P +T K KK + P+ +++ + G +
Sbjct: 181 PTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTV 240
Query: 157 EEES-LVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLS 215
+S GR E+ + + S K++ + TS EK+ A+ KT+
Sbjct: 241 TRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYK 300
Query: 216 EKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTA 275
E + + ++ + + K+ S L S+ E ++
Sbjct: 301 TTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQ---SLAEPTEHGGRTANE 357
Query: 276 DAKPAPKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLA-----KQGASDPP 330
+ P+P T + + A E SPA E R R P A ++ ++
Sbjct: 358 NNTPSPAEPTENRERTANENTTL--SPAEPTENRERTANENTAPFPAGPTENREMTANEN 415
Query: 331 TVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLT 390
T P + ++ + PT+ ++ + ++P +P + T
Sbjct: 416 TTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSP----AEPTEHGERTPFA 471
Query: 391 RSASMKLPDNTVKLGEK--LERYHTAIRRSESVKSRGLPCTE-LFVAPVGVASKRHLFEK 447
+ + + GE+ L +T +E ++R E +P G R
Sbjct: 472 NDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTAN 531
Query: 448 ELAGQSRAEPASSRKENLRLSGVVTSRLNLWISRTQESGDQDPQEAQK-ASSATERTQWG 506
E S EP +R+ + + E+G + P +K SS+ E T+ G
Sbjct: 532 EKTTLSPVEPTENRET------TANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHG 585
Query: 507 QKS 509
+++
Sbjct: 586 ERT 588
>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
sapiens]
Length = 788
Score = 53.5 bits (127), Expect = 4e-07
Identities = 87/440 (19%), Positives = 173/440 (39%), Gaps = 71/440 (16%)
Query: 1 MAVSRKDWSALSSLARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASE 60
+ ++R + L + +E+EE ++ E N + ++ L + E
Sbjct: 96 LELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDEEAREELREQVYDAMGEKE 155
Query: 61 RLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLE------ 114
E+ + KP K++D +++ + R+ + ++A+ P QE+++
Sbjct: 156 EAKKTEDKSLAKP--ETDKEQDSEME------KGGREDMDISKSAEEP-QEKVDLTLDWL 206
Query: 115 ---AEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEE--R 169
+EE + +P + + S K EQ P A EE+S+ G + +E R
Sbjct: 207 TETSEEAKGGAAPEGPNEAEVTSGKP-----------EQEVPDAEEEKSVSGTDVQEECR 255
Query: 170 KKGVPEKSP--VLEKSSMPKKTAPEKSLVS-DKTSISEKVLASEKTSLSEKIAVSEKRNS 226
+KG EK ++ PK+ + E+ +V+ +K + +V E SL + +
Sbjct: 256 EKGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGTAVEV---EAESLDPTVKPVDVGGD 312
Query: 227 SEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATA 286
++ V+ TS +E A + E+ + E P A+ +P+ T
Sbjct: 313 EPEEKVV--TSENEAGKA-----------------VLEQLVGQEVPP---AEESPEVTTE 350
Query: 287 SEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIP 346
+ + A E GS + K PG+ P L K GA + P+V P+ Q I
Sbjct: 351 AAEASAVE----AGSEVSEK-------PGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIE 399
Query: 347 SKEEEADMSSPTQRTYSSSLKRSSPRTISF-RMKPKKENSETTLTRSASMKLPDNTVKLG 405
E D S ++ + + +S + + +T + + A+ K P++ V++
Sbjct: 400 RLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIA 459
Query: 406 EKLERYHTAIRRSESVKSRG 425
E + E ++ G
Sbjct: 460 ANEETQEREEQMKEGEETEG 479
>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
sapiens]
Length = 790
Score = 53.5 bits (127), Expect = 4e-07
Identities = 87/440 (19%), Positives = 173/440 (39%), Gaps = 71/440 (16%)
Query: 1 MAVSRKDWSALSSLARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASE 60
+ ++R + L + +E+EE ++ E N + ++ L + E
Sbjct: 98 LELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDEEAREELREQVYDAMGEKE 157
Query: 61 RLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLE------ 114
E+ + KP K++D +++ + R+ + ++A+ P QE+++
Sbjct: 158 EAKKTEDKSLAKP--ETDKEQDSEME------KGGREDMDISKSAEEP-QEKVDLTLDWL 208
Query: 115 ---AEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEE--R 169
+EE + +P + + S K EQ P A EE+S+ G + +E R
Sbjct: 209 TETSEEAKGGAAPEGPNEAEVTSGKP-----------EQEVPDAEEEKSVSGTDVQEECR 257
Query: 170 KKGVPEKSP--VLEKSSMPKKTAPEKSLVS-DKTSISEKVLASEKTSLSEKIAVSEKRNS 226
+KG EK ++ PK+ + E+ +V+ +K + +V E SL + +
Sbjct: 258 EKGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGTAVEV---EAESLDPTVKPVDVGGD 314
Query: 227 SEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATA 286
++ V+ TS +E A + E+ + E P A+ +P+ T
Sbjct: 315 EPEEKVV--TSENEAGKA-----------------VLEQLVGQEVPP---AEESPEVTTE 352
Query: 287 SEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIP 346
+ + A E GS + K PG+ P L K GA + P+V P+ Q I
Sbjct: 353 AAEASAVE----AGSEVSEK-------PGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIE 401
Query: 347 SKEEEADMSSPTQRTYSSSLKRSSPRTISF-RMKPKKENSETTLTRSASMKLPDNTVKLG 405
E D S ++ + + +S + + +T + + A+ K P++ V++
Sbjct: 402 RLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIA 461
Query: 406 EKLERYHTAIRRSESVKSRG 425
E + E ++ G
Sbjct: 462 ANEETQEREEQMKEGEETEG 481
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 52.8 bits (125), Expect = 8e-07
Identities = 87/410 (21%), Positives = 134/410 (32%), Gaps = 62/410 (15%)
Query: 35 RNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQE 94
++ +TT + AP +++ A + + PS + P P P E + +
Sbjct: 394 KSAPTTTKEPAPTTTKS----APTTPKEPSPTTTKEPAPTTPK-----EPAPTTPKKPAP 444
Query: 95 RRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK---PLVSKKELEIPPRRRLSREQR 151
+ + P + P T K P KK P +
Sbjct: 445 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 504
Query: 152 GPWALEEESLVGREPEERKKGVPEK----SPVLEKSSMPKKTAPEKSLVSDKTSISEKVL 207
P E L PEE PE+ +P + PK+ AP T+ E
Sbjct: 505 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564
Query: 208 ASEK------------TSLSEKIAVSEKRNSSEK---KSVLEKTSVSEKSLAPGMALGSG 252
+ K T+L E + K+ + ++ + E TS + AP G+
Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 624
Query: 253 RRLVSEKASIFEKALA------------SEKSPTADAKPAPKRATASEQPLAQEPPASGG 300
E A K A E +PT KPAPK P + G
Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA---------PTTTKG 675
Query: 301 SPATTKEQRGRALPGKNLPSLAKQGA-----SDPPTVASRLPPVTLQVKIP--SKEEEAD 353
+TT ++ P + P+ K+ A PT PP T +V P +KE
Sbjct: 676 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 735
Query: 354 MSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVK 403
SP + T S + P + PK+ TT T +A+ T K
Sbjct: 736 HKSPDESTPELS---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 782
Score = 38.5 bits (88), Expect = 0.015
Identities = 70/348 (20%), Positives = 127/348 (36%), Gaps = 35/348 (10%)
Query: 40 TTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRR 99
TT E + G + E P+ + PK L P + S ++
Sbjct: 634 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 693
Query: 100 QVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEE 159
AP + A + P + + KE P S ++ P E
Sbjct: 694 PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKSPDESTPELSAEP 750
Query: 160 SLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVS-DKTSISEKVLASEKTSLSEKI 218
+ E ++ GVP + P T PE + + DKT+ + E T+ + K+
Sbjct: 751 TPKALENSPKEPGVPT-------TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 803
Query: 219 -----AVSEKRNSSE-KKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEK- 271
+EK S+ + + TS + + P ++ K + +K + + +
Sbjct: 804 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 863
Query: 272 --SPTADAKPAPKRATASE--QPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGAS 327
P AKP RAT S+ P Q+P + P +TK+ K +P + K +
Sbjct: 864 MNKPEETAKP-KDRATNSKATTPKPQKPTKAPKKPTSTKKP-------KTMPRVRKPKTT 915
Query: 328 DPPTVASRLPPVTLQVKIPSKEEEADMSSPTQ--RTYSSSLKRSSPRT 373
P + P ++ S+ EA + + T+ +T +S L +P++
Sbjct: 916 PTPRKMTSTMP---ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 960
Score = 33.9 bits (76), Expect = 0.37
Identities = 77/365 (21%), Positives = 124/365 (33%), Gaps = 37/365 (10%)
Query: 49 SQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAP 108
S +G + ++++ S+E+ K L P SK +L + + A P
Sbjct: 163 STDGKEKTTSAKETQSIEKTSA-KDLAPTSK--------VLAKPTPKAETTTKGPALTTP 213
Query: 109 IQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEES-LVGREPE 167
+ + S +P + T P K P + + P +E + +EP
Sbjct: 214 KEPTPTTPKEPASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA 271
Query: 168 ERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEK----TSLSEKIAVSEK 223
P + E + K+AP T+ + + K T+ E + K
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 331
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALA----SEKSPTADAKP 279
+ K E + K AP E A K A E SPT +P
Sbjct: 332 EPAPTTK---EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 388
Query: 280 APKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPV 339
AP T P + PA P TTK P + P+ K+ A PT P
Sbjct: 389 AP--TTTKSAPTTTKEPA----PTTTKS--APTTPKEPSPTTTKEPA---PTTPKEPAPT 437
Query: 340 TLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETT---LTRSASMK 396
T + P+ +E ++P + +++ K + KE + TT LT + K
Sbjct: 438 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 497
Query: 397 LPDNT 401
L T
Sbjct: 498 LAPTT 502
Score = 33.1 bits (74), Expect = 0.63
Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 25/191 (13%)
Query: 223 KRNSSEKKSVLEKTSVSEKSLAPGMALGSGR-RLVSEKASIFEKALASEKSPTADAKPA- 280
K+N ++KK + V E G L +G ++ + S + S AKP
Sbjct: 70 KKNRTKKKPTPKPPVVDEA----GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN 125
Query: 281 ------PKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVAS 334
P T+ E L + + TT + + GK + AK+ S T A
Sbjct: 126 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 185
Query: 335 RLPPVTLQVKIPSKEEEADMSSPTQRT------------YSSSLKRSSPRTISFRMKPKK 382
L P + + P+ + E P T S++ K +P TI K
Sbjct: 186 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 245
Query: 383 ENSETTLTRSA 393
E + TT T+SA
Sbjct: 246 EPAPTT-TKSA 255
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 52.8 bits (125), Expect = 8e-07
Identities = 87/410 (21%), Positives = 134/410 (32%), Gaps = 62/410 (15%)
Query: 35 RNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQE 94
++ +TT + AP +++ A + + PS + P P P E + +
Sbjct: 435 KSAPTTTKEPAPTTTKS----APTTPKEPSPTTTKEPAPTTPK-----EPAPTTPKKPAP 485
Query: 95 RRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK---PLVSKKELEIPPRRRLSREQR 151
+ + P + P T K P KK P +
Sbjct: 486 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 545
Query: 152 GPWALEEESLVGREPEERKKGVPEK----SPVLEKSSMPKKTAPEKSLVSDKTSISEKVL 207
P E L PEE PE+ +P + PK+ AP T+ E
Sbjct: 546 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605
Query: 208 ASEK------------TSLSEKIAVSEKRNSSEK---KSVLEKTSVSEKSLAPGMALGSG 252
+ K T+L E + K+ + ++ + E TS + AP G+
Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 665
Query: 253 RRLVSEKASIFEKALA------------SEKSPTADAKPAPKRATASEQPLAQEPPASGG 300
E A K A E +PT KPAPK P + G
Sbjct: 666 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA---------PTTTKG 716
Query: 301 SPATTKEQRGRALPGKNLPSLAKQGA-----SDPPTVASRLPPVTLQVKIP--SKEEEAD 353
+TT ++ P + P+ K+ A PT PP T +V P +KE
Sbjct: 717 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 776
Query: 354 MSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVK 403
SP + T S + P + PK+ TT T +A+ T K
Sbjct: 777 HKSPDESTPELS---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 823
Score = 38.5 bits (88), Expect = 0.015
Identities = 70/348 (20%), Positives = 127/348 (36%), Gaps = 35/348 (10%)
Query: 40 TTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRR 99
TT E + G + E P+ + PK L P + S ++
Sbjct: 675 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 734
Query: 100 QVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEE 159
AP + A + P + + KE P S ++ P E
Sbjct: 735 PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKSPDESTPELSAEP 791
Query: 160 SLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVS-DKTSISEKVLASEKTSLSEKI 218
+ E ++ GVP + P T PE + + DKT+ + E T+ + K+
Sbjct: 792 TPKALENSPKEPGVPT-------TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 844
Query: 219 -----AVSEKRNSSE-KKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEK- 271
+EK S+ + + TS + + P ++ K + +K + + +
Sbjct: 845 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 904
Query: 272 --SPTADAKPAPKRATASE--QPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGAS 327
P AKP RAT S+ P Q+P + P +TK+ K +P + K +
Sbjct: 905 MNKPEETAKP-KDRATNSKATTPKPQKPTKAPKKPTSTKKP-------KTMPRVRKPKTT 956
Query: 328 DPPTVASRLPPVTLQVKIPSKEEEADMSSPTQ--RTYSSSLKRSSPRT 373
P + P ++ S+ EA + + T+ +T +S L +P++
Sbjct: 957 PTPRKMTSTMP---ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 1001
Score = 33.9 bits (76), Expect = 0.37
Identities = 77/365 (21%), Positives = 124/365 (33%), Gaps = 37/365 (10%)
Query: 49 SQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAP 108
S +G + ++++ S+E+ K L P SK +L + + A P
Sbjct: 204 STDGKEKTTSAKETQSIEKTSA-KDLAPTSK--------VLAKPTPKAETTTKGPALTTP 254
Query: 109 IQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEES-LVGREPE 167
+ + S +P + T P K P + + P +E + +EP
Sbjct: 255 KEPTPTTPKEPASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA 312
Query: 168 ERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEK----TSLSEKIAVSEK 223
P + E + K+AP T+ + + K T+ E + K
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 372
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALA----SEKSPTADAKP 279
+ K E + K AP E A K A E SPT +P
Sbjct: 373 EPAPTTK---EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 429
Query: 280 APKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPV 339
AP T P + PA P TTK P + P+ K+ A PT P
Sbjct: 430 AP--TTTKSAPTTTKEPA----PTTTKS--APTTPKEPSPTTTKEPA---PTTPKEPAPT 478
Query: 340 TLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETT---LTRSASMK 396
T + P+ +E ++P + +++ K + KE + TT LT + K
Sbjct: 479 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 538
Query: 397 LPDNT 401
L T
Sbjct: 539 LAPTT 543
Score = 33.1 bits (74), Expect = 0.63
Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 25/191 (13%)
Query: 223 KRNSSEKKSVLEKTSVSEKSLAPGMALGSGR-RLVSEKASIFEKALASEKSPTADAKPA- 280
K+N ++KK + V E G L +G ++ + S + S AKP
Sbjct: 111 KKNRTKKKPTPKPPVVDEA----GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN 166
Query: 281 ------PKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVAS 334
P T+ E L + + TT + + GK + AK+ S T A
Sbjct: 167 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 226
Query: 335 RLPPVTLQVKIPSKEEEADMSSPTQRT------------YSSSLKRSSPRTISFRMKPKK 382
L P + + P+ + E P T S++ K +P TI K
Sbjct: 227 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 286
Query: 383 ENSETTLTRSA 393
E + TT T+SA
Sbjct: 287 EPAPTT-TKSA 296
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 52.8 bits (125), Expect = 8e-07
Identities = 87/410 (21%), Positives = 134/410 (32%), Gaps = 62/410 (15%)
Query: 35 RNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQE 94
++ +TT + AP +++ A + + PS + P P P E + +
Sbjct: 487 KSAPTTTKEPAPTTTKS----APTTPKEPSPTTTKEPAPTTPK-----EPAPTTPKKPAP 537
Query: 95 RRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK---PLVSKKELEIPPRRRLSREQR 151
+ + P + P T K P KK P +
Sbjct: 538 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 597
Query: 152 GPWALEEESLVGREPEERKKGVPEK----SPVLEKSSMPKKTAPEKSLVSDKTSISEKVL 207
P E L PEE PE+ +P + PK+ AP T+ E
Sbjct: 598 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657
Query: 208 ASEK------------TSLSEKIAVSEKRNSSEK---KSVLEKTSVSEKSLAPGMALGSG 252
+ K T+L E + K+ + ++ + E TS + AP G+
Sbjct: 658 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 717
Query: 253 RRLVSEKASIFEKALA------------SEKSPTADAKPAPKRATASEQPLAQEPPASGG 300
E A K A E +PT KPAPK P + G
Sbjct: 718 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA---------PTTTKG 768
Query: 301 SPATTKEQRGRALPGKNLPSLAKQGA-----SDPPTVASRLPPVTLQVKIP--SKEEEAD 353
+TT ++ P + P+ K+ A PT PP T +V P +KE
Sbjct: 769 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 828
Query: 354 MSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVK 403
SP + T S + P + PK+ TT T +A+ T K
Sbjct: 829 HKSPDESTPELS---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 875
Score = 45.8 bits (107), Expect = 9e-05
Identities = 59/256 (23%), Positives = 99/256 (38%), Gaps = 30/256 (11%)
Query: 164 REPEERK-KGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTS-----LSEK 217
+ P ++K K V E + E+ S+ + S S +S + + + S K S L +K
Sbjct: 97 KPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKK 156
Query: 218 IAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGR-RLVSEKASIFEKALASEKSPTAD 276
+ V + + + KK K V +++ G L +G ++ + S + S
Sbjct: 157 LKVKDNKKNRTKKKPTPKPPVVDEA---GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT 213
Query: 277 AKPA-------PKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDP 329
AKP P T+ E L + + TT + + GK + AK+ S
Sbjct: 214 AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 273
Query: 330 PTVASRLPPVTLQVKIPSKEEEADMSSPTQRT------------YSSSLKRSSPRTISFR 377
T A L P + + P+ + E P T S++ K +P TI
Sbjct: 274 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 333
Query: 378 MKPKKENSETTLTRSA 393
KE + TT T+SA
Sbjct: 334 PTTPKEPAPTT-TKSA 348
Score = 38.5 bits (88), Expect = 0.015
Identities = 70/348 (20%), Positives = 127/348 (36%), Gaps = 35/348 (10%)
Query: 40 TTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRR 99
TT E + G + E P+ + PK L P + S ++
Sbjct: 727 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 786
Query: 100 QVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEE 159
AP + A + P + + KE P S ++ P E
Sbjct: 787 PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKSPDESTPELSAEP 843
Query: 160 SLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVS-DKTSISEKVLASEKTSLSEKI 218
+ E ++ GVP + P T PE + + DKT+ + E T+ + K+
Sbjct: 844 TPKALENSPKEPGVPT-------TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 896
Query: 219 -----AVSEKRNSSE-KKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEK- 271
+EK S+ + + TS + + P ++ K + +K + + +
Sbjct: 897 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 956
Query: 272 --SPTADAKPAPKRATASE--QPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGAS 327
P AKP RAT S+ P Q+P + P +TK+ K +P + K +
Sbjct: 957 MNKPEETAKP-KDRATNSKATTPKPQKPTKAPKKPTSTKKP-------KTMPRVRKPKTT 1008
Query: 328 DPPTVASRLPPVTLQVKIPSKEEEADMSSPTQ--RTYSSSLKRSSPRT 373
P + P ++ S+ EA + + T+ +T +S L +P++
Sbjct: 1009 PTPRKMTSTMP---ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 1053
Score = 33.9 bits (76), Expect = 0.37
Identities = 77/365 (21%), Positives = 124/365 (33%), Gaps = 37/365 (10%)
Query: 49 SQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAP 108
S +G + ++++ S+E+ K L P SK +L + + A P
Sbjct: 256 STDGKEKTTSAKETQSIEKTSA-KDLAPTSK--------VLAKPTPKAETTTKGPALTTP 306
Query: 109 IQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEES-LVGREPE 167
+ + S +P + T P K P + + P +E + +EP
Sbjct: 307 KEPTPTTPKEPASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA 364
Query: 168 ERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEK----TSLSEKIAVSEK 223
P + E + K+AP T+ + + K T+ E + K
Sbjct: 365 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 424
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALA----SEKSPTADAKP 279
+ K E + K AP E A K A E SPT +P
Sbjct: 425 EPAPTTK---EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 481
Query: 280 APKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPV 339
AP T P + PA P TTK P + P+ K+ A PT P
Sbjct: 482 AP--TTTKSAPTTTKEPA----PTTTKS--APTTPKEPSPTTTKEPA---PTTPKEPAPT 530
Query: 340 TLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETT---LTRSASMK 396
T + P+ +E ++P + +++ K + KE + TT LT + K
Sbjct: 531 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 590
Query: 397 LPDNT 401
L T
Sbjct: 591 LAPTT 595
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 52.8 bits (125), Expect = 8e-07
Identities = 87/410 (21%), Positives = 134/410 (32%), Gaps = 62/410 (15%)
Query: 35 RNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQE 94
++ +TT + AP +++ A + + PS + P P P E + +
Sbjct: 528 KSAPTTTKEPAPTTTKS----APTTPKEPSPTTTKEPAPTTPK-----EPAPTTPKKPAP 578
Query: 95 RRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK---PLVSKKELEIPPRRRLSREQR 151
+ + P + P T K P KK P +
Sbjct: 579 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 638
Query: 152 GPWALEEESLVGREPEERKKGVPEK----SPVLEKSSMPKKTAPEKSLVSDKTSISEKVL 207
P E L PEE PE+ +P + PK+ AP T+ E
Sbjct: 639 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698
Query: 208 ASEK------------TSLSEKIAVSEKRNSSEK---KSVLEKTSVSEKSLAPGMALGSG 252
+ K T+L E + K+ + ++ + E TS + AP G+
Sbjct: 699 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 758
Query: 253 RRLVSEKASIFEKALA------------SEKSPTADAKPAPKRATASEQPLAQEPPASGG 300
E A K A E +PT KPAPK P + G
Sbjct: 759 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA---------PTTTKG 809
Query: 301 SPATTKEQRGRALPGKNLPSLAKQGA-----SDPPTVASRLPPVTLQVKIP--SKEEEAD 353
+TT ++ P + P+ K+ A PT PP T +V P +KE
Sbjct: 810 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 869
Query: 354 MSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVK 403
SP + T S + P + PK+ TT T +A+ T K
Sbjct: 870 HKSPDESTPELS---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 916
Score = 45.8 bits (107), Expect = 9e-05
Identities = 59/256 (23%), Positives = 99/256 (38%), Gaps = 30/256 (11%)
Query: 164 REPEERK-KGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTS-----LSEK 217
+ P ++K K V E + E+ S+ + S S +S + + + S K S L +K
Sbjct: 138 KPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKK 197
Query: 218 IAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGR-RLVSEKASIFEKALASEKSPTAD 276
+ V + + + KK K V +++ G L +G ++ + S + S
Sbjct: 198 LKVKDNKKNRTKKKPTPKPPVVDEA---GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT 254
Query: 277 AKPA-------PKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDP 329
AKP P T+ E L + + TT + + GK + AK+ S
Sbjct: 255 AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 314
Query: 330 PTVASRLPPVTLQVKIPSKEEEADMSSPTQRT------------YSSSLKRSSPRTISFR 377
T A L P + + P+ + E P T S++ K +P TI
Sbjct: 315 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 374
Query: 378 MKPKKENSETTLTRSA 393
KE + TT T+SA
Sbjct: 375 PTTPKEPAPTT-TKSA 389
Score = 38.5 bits (88), Expect = 0.015
Identities = 70/348 (20%), Positives = 127/348 (36%), Gaps = 35/348 (10%)
Query: 40 TTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRR 99
TT E + G + E P+ + PK L P + S ++
Sbjct: 768 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 827
Query: 100 QVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEE 159
AP + A + P + + KE P S ++ P E
Sbjct: 828 PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKSPDESTPELSAEP 884
Query: 160 SLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVS-DKTSISEKVLASEKTSLSEKI 218
+ E ++ GVP + P T PE + + DKT+ + E T+ + K+
Sbjct: 885 TPKALENSPKEPGVPT-------TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 937
Query: 219 -----AVSEKRNSSE-KKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEK- 271
+EK S+ + + TS + + P ++ K + +K + + +
Sbjct: 938 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 997
Query: 272 --SPTADAKPAPKRATASE--QPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGAS 327
P AKP RAT S+ P Q+P + P +TK+ K +P + K +
Sbjct: 998 MNKPEETAKP-KDRATNSKATTPKPQKPTKAPKKPTSTKKP-------KTMPRVRKPKTT 1049
Query: 328 DPPTVASRLPPVTLQVKIPSKEEEADMSSPTQ--RTYSSSLKRSSPRT 373
P + P ++ S+ EA + + T+ +T +S L +P++
Sbjct: 1050 PTPRKMTSTMP---ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 1094
Score = 33.9 bits (76), Expect = 0.37
Identities = 77/365 (21%), Positives = 124/365 (33%), Gaps = 37/365 (10%)
Query: 49 SQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAP 108
S +G + ++++ S+E+ K L P SK +L + + A P
Sbjct: 297 STDGKEKTTSAKETQSIEKTSA-KDLAPTSK--------VLAKPTPKAETTTKGPALTTP 347
Query: 109 IQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEES-LVGREPE 167
+ + S +P + T P K P + + P +E + +EP
Sbjct: 348 KEPTPTTPKEPASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA 405
Query: 168 ERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEK----TSLSEKIAVSEK 223
P + E + K+AP T+ + + K T+ E + K
Sbjct: 406 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 465
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALA----SEKSPTADAKP 279
+ K E + K AP E A K A E SPT +P
Sbjct: 466 EPAPTTK---EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 522
Query: 280 APKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPV 339
AP T P + PA P TTK P + P+ K+ A PT P
Sbjct: 523 AP--TTTKSAPTTTKEPA----PTTTKS--APTTPKEPSPTTTKEPA---PTTPKEPAPT 571
Query: 340 TLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETT---LTRSASMK 396
T + P+ +E ++P + +++ K + KE + TT LT + K
Sbjct: 572 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 631
Query: 397 LPDNT 401
L T
Sbjct: 632 LAPTT 636
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 52.0 bits (123), Expect = 1e-06
Identities = 51/200 (25%), Positives = 79/200 (39%), Gaps = 30/200 (15%)
Query: 110 QERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEER 169
Q+ + G N + P + + + P +R +S ++ + + V R P
Sbjct: 298 QKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPD 357
Query: 170 KKGVPEKSPVLEKSSMPKKT-------APEKSL-VSDKTSI-----SEKVLASEKTSLSE 216
K PE+ P E + KK +PEK+L + DK SI S K+ A +K E
Sbjct: 358 KTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPE 417
Query: 217 KIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTAD 276
K+ E +K S+ E S+ P L +K S E+ + E+SP +
Sbjct: 418 KMVTPE-----------DKASIPENSIIPE------ETLTVDKPSTPERVFSVEESPALE 460
Query: 277 AKPAPKRATASEQPLAQEPP 296
A P K PL E P
Sbjct: 461 APPMDKVPNPKMAPLGDEAP 480
Score = 40.4 bits (93), Expect = 0.004
Identities = 63/239 (26%), Positives = 99/239 (41%), Gaps = 33/239 (13%)
Query: 156 LEEESLVGREPE--ERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKV----LAS 209
+ EE+L +P ER V E+SP LE M K P+ + + D+ EKV L+
Sbjct: 434 IPEETLTVDKPSTPERVFSV-EESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSE 492
Query: 210 EKTSLSEKIAV----SEKRNSSEKKSVLEKTSVSEKSL----APGMALGSGRRLVSEKAS 261
E+ S + I SE+ K V ++ S++ AP S R + E
Sbjct: 493 EEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKC 552
Query: 262 IFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQR---GRALPGKNL 318
+ +S + A+ K P A E+P E + A + ++R A P +
Sbjct: 553 TLVRGDSSPRQ--AELKSGPASRPALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQR 610
Query: 319 P----SLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSS--PTQRTYSSSLKRSSP 371
P L K+G VAS+ VTL+ ++P KEE A P +R ++ + P
Sbjct: 611 PLREEVLPKEG------VASK-EEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKP 662
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 52.0 bits (123), Expect = 1e-06
Identities = 51/200 (25%), Positives = 79/200 (39%), Gaps = 30/200 (15%)
Query: 110 QERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEER 169
Q+ + G N + P + + + P +R +S ++ + + V R P
Sbjct: 187 QKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPD 246
Query: 170 KKGVPEKSPVLEKSSMPKKT-------APEKSL-VSDKTSI-----SEKVLASEKTSLSE 216
K PE+ P E + KK +PEK+L + DK SI S K+ A +K E
Sbjct: 247 KTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPE 306
Query: 217 KIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTAD 276
K+ E +K S+ E S+ P L +K S E+ + E+SP +
Sbjct: 307 KMVTPE-----------DKASIPENSIIPE------ETLTVDKPSTPERVFSVEESPALE 349
Query: 277 AKPAPKRATASEQPLAQEPP 296
A P K PL E P
Sbjct: 350 APPMDKVPNPKMAPLGDEAP 369
Score = 40.4 bits (93), Expect = 0.004
Identities = 63/239 (26%), Positives = 99/239 (41%), Gaps = 33/239 (13%)
Query: 156 LEEESLVGREPE--ERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKV----LAS 209
+ EE+L +P ER V E+SP LE M K P+ + + D+ EKV L+
Sbjct: 323 IPEETLTVDKPSTPERVFSV-EESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSE 381
Query: 210 EKTSLSEKIAV----SEKRNSSEKKSVLEKTSVSEKSL----APGMALGSGRRLVSEKAS 261
E+ S + I SE+ K V ++ S++ AP S R + E
Sbjct: 382 EEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKC 441
Query: 262 IFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQR---GRALPGKNL 318
+ +S + A+ K P A E+P E + A + ++R A P +
Sbjct: 442 TLVRGDSSPRQ--AELKSGPASRPALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQR 499
Query: 319 P----SLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSS--PTQRTYSSSLKRSSP 371
P L K+G VAS+ VTL+ ++P KEE A P +R ++ + P
Sbjct: 500 PLREEVLPKEG------VASK-EEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKP 551
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 52.0 bits (123), Expect = 1e-06
Identities = 84/346 (24%), Positives = 124/346 (35%), Gaps = 44/346 (12%)
Query: 38 SSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQ 97
+ T D+A + NG L SV V P PA K I+R
Sbjct: 442 TGTNKDKAEFILPNGQEVDLPISYLTSVSSLIVWHPANPAEK--------IIRVLFPGN- 492
Query: 98 RRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRL-----SREQRG 152
+ Q I E LE + + L ATQK L + + + +L SRE
Sbjct: 493 ------STQYNILEGLEKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLK 546
Query: 153 PWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSD--------KTSISE 204
P A S R+ E K+ PE + V PK + EK +V K S++E
Sbjct: 547 PAAKPLPSKSVRK--ESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTE 604
Query: 205 KVLASEKTSLSEKIAVSEKRNSSEK-KSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIF 263
K + S++ K V+EK+ + K K+ EKT E + P + E A
Sbjct: 605 KEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKE 664
Query: 264 EKA--LASEKSPTADAKPAPKRATASEQ------PLAQEPPASGGSPATTKEQRGRAL-- 313
+K EK + K K+ E+ + +E P KE++
Sbjct: 665 DKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKE 724
Query: 314 ---PGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSS 356
P K + L K ++ P L+ K+P KEE S
Sbjct: 725 EKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDS 770
Score = 45.1 bits (105), Expect = 2e-04
Identities = 56/250 (22%), Positives = 100/250 (40%), Gaps = 43/250 (17%)
Query: 59 SERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEG 118
+E PSV E EVP SK+E +++ +V E ++ + E+
Sbjct: 596 TETKPSVTEKEVP------SKEEPSPVKA------------EVAEKQATDVKPKAAKEKT 637
Query: 119 RNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSP 178
+ V KP K+E E P + +E + P EE+ +E KK + ++
Sbjct: 638 VKKETKV----KPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEK 693
Query: 179 VLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSV 238
K + K+T P++ + ++V EK + +K KK + +
Sbjct: 694 KEPKKEVKKETPPKE--------VKKEVKKEEKKEV-------KKEEKEPKKEIKKLPKD 738
Query: 239 SEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPK---RATASEQPLAQEP 295
++KS P L ++ + K + +K + +K A KP K + E A+
Sbjct: 739 AKKSSTP---LSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAV 795
Query: 296 PASGGSPATT 305
A+ G+ ATT
Sbjct: 796 AAAVGTGATT 805
Score = 36.2 bits (82), Expect = 0.074
Identities = 75/359 (20%), Positives = 133/359 (37%), Gaps = 53/359 (14%)
Query: 165 EPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSL-----SEKIA 219
E E+ PE ++S P+ S +T+ EK+ + + S S+
Sbjct: 2009 ETTEKITSFPESEGYSYETSTKTTRTPDTSTYCYETA--EKITRTPQASTYSYETSDLCY 2066
Query: 220 VSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKP 279
+EK++ SE + ++ VS S K +E SP+ P
Sbjct: 2067 TAEKKSPSEARQDVDLCLVS---------------------SCEYKHPKTELSPSF-INP 2104
Query: 280 APKRATASEQPLAQ-EPPA--SGGSPATTK-EQRGRAL----PGKNLPSLAKQGASDPPT 331
P ASE+P + E P SGG+P +Q+GR P S Q SD P
Sbjct: 2105 NPLEWFASEEPTEESEKPLTQSGGAPPPPGGKQQGRQCDETPPTSVSESAPSQTDSDVPP 2164
Query: 332 VASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTR 391
P +T I S++E + PT +T + P + R P + + ++
Sbjct: 2165 ETEECPSITADANIDSEDESETI--PTDKTVTYKHMDPPPAPVQDR-SPSPRHPDVSMVD 2221
Query: 392 SASMKLPDN-------TVKLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHL 444
++ + N +K K ++ T + S VK L AS +
Sbjct: 2222 PEALAIEQNLGKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPL------AASPKPA 2275
Query: 445 FEKELAGQSRAEPASSRKENLRLSGVVTSRLNLWISRTQESGDQDPQEAQKASSATERT 503
KE + + + +KE++ + T+ + +R +E + A ++S + +T
Sbjct: 2276 GLKESSDKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKT 2334
Score = 29.6 bits (65), Expect = 6.9
Identities = 40/169 (23%), Positives = 63/169 (37%), Gaps = 30/169 (17%)
Query: 166 PEERKKGVPEKSPVLEKSSMP---KKTAPEKSLVSD----------------------KT 200
P+ K P + E+SSM + +PE+SL D T
Sbjct: 1626 PKTAKSRTPVQDHRSEQSSMSIEFGQESPEQSLAMDFSRQSPDHPTVGAGVLHITENGPT 1685
Query: 201 SISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKA 260
+ + +SLS KI E+ + ++ + E SVS+ +P S S+ A
Sbjct: 1686 EVDYSPSDMQDSSLSHKIPPMEEPSYTQDNDLSELISVSQVEASPST---SSAHTPSQIA 1742
Query: 261 SIFEKALASEKSPTADAKPAPKRATASEQPLAQE--PPASGGSPATTKE 307
S ++ S+ +P D + Q L E P S SP T +E
Sbjct: 1743 SPLQEDTLSDVAPPRDMSLYASLTSEKVQSLEGEKLSPKSDISPLTPRE 1791
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 50.8 bits (120), Expect = 3e-06
Identities = 71/297 (23%), Positives = 137/297 (46%), Gaps = 33/297 (11%)
Query: 16 RQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASER--LPSVEEAEVPKP 73
R+ D ++Q+R + + L +++ E Q RQA A+ER L EE V +
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEI----QAKARQAEAAERSRLRIEEEIRVVRL 1459
Query: 74 LPPASKDE----DEDIQSI-LRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQAT 128
A++ + + ++Q++ R + Q+RQ E A+ ++ +++ E R + V+
Sbjct: 1460 QLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER-LRRQVQDESQRKRQAEVE-- 1516
Query: 129 QKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEER-KKGVPEKSPVLEKSSMPK 187
L S+ + E R +QR ALEE L E E R ++ E++ ++ +
Sbjct: 1517 ---LASRVKAEAEAARE---KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1570
Query: 188 KTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTS-----VSEKS 242
+ + E L S + S +EK E++ E +AV++ R +E+++ + + +E+
Sbjct: 1571 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1630
Query: 243 LAPGMALGSGR---RLVSEKASIFEKALA---SEKSPTADAKPAPKRATASEQPLAQ 293
L + RL +E+ + +K+LA +EK + A +R A EQ + Q
Sbjct: 1631 LERWQLKANEALRLRLQAEEVA-QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1686
Score = 48.1 bits (113), Expect = 2e-05
Identities = 110/496 (22%), Positives = 194/496 (39%), Gaps = 66/496 (13%)
Query: 13 SLARQRTLEDEEEQERERRR---------RHRNLSSTTDDEAPRLSQNGDRQASASER-- 61
SLA+ + +EE ERE RR R R L+ ++ +L++ +Q A+E+
Sbjct: 1656 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQEL 1715
Query: 62 ---LPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEG 118
E+ E + L +E++ + R Q+RQ +EA A ++ +E
Sbjct: 1716 IRLRAETEQGEQQRQL------LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLA 1769
Query: 119 RNSLSPVQATQKPLVSKKELEIPPR--RRLSREQRGPWALEEESL---------VGREPE 167
+ + ++ SK+ LE R L+ E AL EE+ R+
Sbjct: 1770 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRA 1829
Query: 168 ERKKGVPEKSPVLEKSSMPKKTA----PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEK 223
E ++ + EK + +++ K A EK +++ + A ++ L E+ A K
Sbjct: 1830 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ-AAQHK 1888
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGS--GRRLVSE-----KASIFEKALASEKSPTAD 276
+ E+ + L K S SE G+ + RR V E KAS FEKA A + +
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKAS-FEKAAAGKAELELE 1947
Query: 277 AKPAPKRA--TASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVAS 334
A T + A+ A A +E+R R + SLA + + A+
Sbjct: 1948 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAA 2007
Query: 335 RLPPVTLQVKIPS-----KEEEADMSSPTQRTYSSSLKR--SSPRTISFRMKPKKENSET 387
L+ K+ + E + + Q ++ KR + + +F ++ K++ +
Sbjct: 2008 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2067
Query: 388 TLTRSASMKLPDNTVKLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEK 447
TL + S+ ++L A RR+ E A S+R + E
Sbjct: 2068 TLQQEQSVL---------DQLRGEAEAARRAAEEAEEARVQAEREAA----QSRRQVEEA 2114
Query: 448 ELAGQSRAEPASSRKE 463
E QS E A +R +
Sbjct: 2115 ERLKQSAEEQAQARAQ 2130
Score = 43.5 bits (101), Expect = 5e-04
Identities = 54/217 (24%), Positives = 94/217 (43%), Gaps = 24/217 (11%)
Query: 15 ARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPL 74
ARQR L EEE+ R S ++EA R +R ++EE E K
Sbjct: 1970 ARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------------QRKAALEEVERLK-- 2015
Query: 75 PPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVS 134
+K E+ LR R E+ RQ ++ AQ Q+RL+AEE ++ + VQ ++ L
Sbjct: 2016 ---AKVEE---ARRLRERAEQESARQ-LQLAQEAAQKRLQAEEKAHAFA-VQQKEQELQQ 2067
Query: 135 KKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKS 194
+ E +L E EE+ R ER+ + +E++ K++A E++
Sbjct: 2068 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ--VEEAERLKQSAEEQA 2125
Query: 195 LVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKS 231
+ + + L E + + A +E+ +K++
Sbjct: 2126 QARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2162
Score = 36.2 bits (82), Expect = 0.074
Identities = 82/388 (21%), Positives = 151/388 (38%), Gaps = 53/388 (13%)
Query: 17 QRTLEDEE------EQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEV 70
+R+L++E +E ERR + + + +EA R + +A+ + RL E
Sbjct: 1593 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE--- 1649
Query: 71 PKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK 130
E Q++ + +A +E E E R + QA ++
Sbjct: 1650 -----------------------EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1686
Query: 131 PLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTA 190
++++ELE ++R E L E + R E ++G ++ + E+ + ++
Sbjct: 1687 RELAEQELE---KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR-- 1741
Query: 191 PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALG 250
E + + K E LA + + E + S+ R E +S EK+ ++ A G
Sbjct: 1742 -EAAAATQKRQELEAELAKVRAEM-EVLLASKARAEEESRSTSEKSKQRLEAEA-----G 1794
Query: 251 SGRRLVSEKASIFEKALASE-KSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQR 309
R L E A + +ALA E K A+ R A + + E A+ G K +
Sbjct: 1795 RFRELAEEAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEA 1852
Query: 310 GRALPGKNLPS-LAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKR 368
AL K + ++ A D RL Q K +E A + ++ S L+R
Sbjct: 1853 EIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL----RKASDSELER 1908
Query: 369 SSPRTISFRMKPKKENSETTLTRSASMK 396
+ ++ +++ E L AS +
Sbjct: 1909 QK-GLVEDTLRQRRQVEEEILALKASFE 1935
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 50.8 bits (120), Expect = 3e-06
Identities = 71/297 (23%), Positives = 137/297 (46%), Gaps = 33/297 (11%)
Query: 16 RQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASER--LPSVEEAEVPKP 73
R+ D ++Q+R + + L +++ E Q RQA A+ER L EE V +
Sbjct: 1408 REEAAVDAQQQKRSIQEELQQLRQSSEAEI----QAKARQAEAAERSRLRIEEEIRVVRL 1463
Query: 74 LPPASKDE----DEDIQSI-LRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQAT 128
A++ + + ++Q++ R + Q+RQ E A+ ++ +++ E R + V+
Sbjct: 1464 QLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER-LRRQVQDESQRKRQAEVE-- 1520
Query: 129 QKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEER-KKGVPEKSPVLEKSSMPK 187
L S+ + E R +QR ALEE L E E R ++ E++ ++ +
Sbjct: 1521 ---LASRVKAEAEAARE---KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1574
Query: 188 KTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTS-----VSEKS 242
+ + E L S + S +EK E++ E +AV++ R +E+++ + + +E+
Sbjct: 1575 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1634
Query: 243 LAPGMALGSGR---RLVSEKASIFEKALA---SEKSPTADAKPAPKRATASEQPLAQ 293
L + RL +E+ + +K+LA +EK + A +R A EQ + Q
Sbjct: 1635 LERWQLKANEALRLRLQAEEVA-QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1690
Score = 48.1 bits (113), Expect = 2e-05
Identities = 110/496 (22%), Positives = 194/496 (39%), Gaps = 66/496 (13%)
Query: 13 SLARQRTLEDEEEQERERRR---------RHRNLSSTTDDEAPRLSQNGDRQASASER-- 61
SLA+ + +EE ERE RR R R L+ ++ +L++ +Q A+E+
Sbjct: 1660 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQEL 1719
Query: 62 ---LPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEG 118
E+ E + L +E++ + R Q+RQ +EA A ++ +E
Sbjct: 1720 IRLRAETEQGEQQRQL------LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLA 1773
Query: 119 RNSLSPVQATQKPLVSKKELEIPPR--RRLSREQRGPWALEEESL---------VGREPE 167
+ + ++ SK+ LE R L+ E AL EE+ R+
Sbjct: 1774 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRA 1833
Query: 168 ERKKGVPEKSPVLEKSSMPKKTA----PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEK 223
E ++ + EK + +++ K A EK +++ + A ++ L E+ A K
Sbjct: 1834 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ-AAQHK 1892
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGS--GRRLVSE-----KASIFEKALASEKSPTAD 276
+ E+ + L K S SE G+ + RR V E KAS FEKA A + +
Sbjct: 1893 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKAS-FEKAAAGKAELELE 1951
Query: 277 AKPAPKRA--TASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVAS 334
A T + A+ A A +E+R R + SLA + + A+
Sbjct: 1952 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAA 2011
Query: 335 RLPPVTLQVKIPS-----KEEEADMSSPTQRTYSSSLKR--SSPRTISFRMKPKKENSET 387
L+ K+ + E + + Q ++ KR + + +F ++ K++ +
Sbjct: 2012 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2071
Query: 388 TLTRSASMKLPDNTVKLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEK 447
TL + S+ ++L A RR+ E A S+R + E
Sbjct: 2072 TLQQEQSVL---------DQLRGEAEAARRAAEEAEEARVQAEREAA----QSRRQVEEA 2118
Query: 448 ELAGQSRAEPASSRKE 463
E QS E A +R +
Sbjct: 2119 ERLKQSAEEQAQARAQ 2134
Score = 43.5 bits (101), Expect = 5e-04
Identities = 54/217 (24%), Positives = 94/217 (43%), Gaps = 24/217 (11%)
Query: 15 ARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPL 74
ARQR L EEE+ R S ++EA R +R ++EE E K
Sbjct: 1974 ARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------------QRKAALEEVERLK-- 2019
Query: 75 PPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVS 134
+K E+ LR R E+ RQ ++ AQ Q+RL+AEE ++ + VQ ++ L
Sbjct: 2020 ---AKVEE---ARRLRERAEQESARQ-LQLAQEAAQKRLQAEEKAHAFA-VQQKEQELQQ 2071
Query: 135 KKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKS 194
+ E +L E EE+ R ER+ + +E++ K++A E++
Sbjct: 2072 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ--VEEAERLKQSAEEQA 2129
Query: 195 LVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKS 231
+ + + L E + + A +E+ +K++
Sbjct: 2130 QARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2166
Score = 36.2 bits (82), Expect = 0.074
Identities = 82/388 (21%), Positives = 151/388 (38%), Gaps = 53/388 (13%)
Query: 17 QRTLEDEE------EQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEV 70
+R+L++E +E ERR + + + +EA R + +A+ + RL E
Sbjct: 1597 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE--- 1653
Query: 71 PKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK 130
E Q++ + +A +E E E R + QA ++
Sbjct: 1654 -----------------------EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1690
Query: 131 PLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTA 190
++++ELE ++R E L E + R E ++G ++ + E+ + ++
Sbjct: 1691 RELAEQELE---KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR-- 1745
Query: 191 PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALG 250
E + + K E LA + + E + S+ R E +S EK+ ++ A G
Sbjct: 1746 -EAAAATQKRQELEAELAKVRAEM-EVLLASKARAEEESRSTSEKSKQRLEAEA-----G 1798
Query: 251 SGRRLVSEKASIFEKALASE-KSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQR 309
R L E A + +ALA E K A+ R A + + E A+ G K +
Sbjct: 1799 RFRELAEEAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEA 1856
Query: 310 GRALPGKNLPS-LAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKR 368
AL K + ++ A D RL Q K +E A + ++ S L+R
Sbjct: 1857 EIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL----RKASDSELER 1912
Query: 369 SSPRTISFRMKPKKENSETTLTRSASMK 396
+ ++ +++ E L AS +
Sbjct: 1913 QK-GLVEDTLRQRRQVEEEILALKASFE 1939
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 50.8 bits (120), Expect = 3e-06
Identities = 71/297 (23%), Positives = 137/297 (46%), Gaps = 33/297 (11%)
Query: 16 RQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASER--LPSVEEAEVPKP 73
R+ D ++Q+R + + L +++ E Q RQA A+ER L EE V +
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEI----QAKARQAEAAERSRLRIEEEIRVVRL 1459
Query: 74 LPPASKDE----DEDIQSI-LRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQAT 128
A++ + + ++Q++ R + Q+RQ E A+ ++ +++ E R + V+
Sbjct: 1460 QLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER-LRRQVQDESQRKRQAEVE-- 1516
Query: 129 QKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEER-KKGVPEKSPVLEKSSMPK 187
L S+ + E R +QR ALEE L E E R ++ E++ ++ +
Sbjct: 1517 ---LASRVKAEAEAARE---KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1570
Query: 188 KTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTS-----VSEKS 242
+ + E L S + S +EK E++ E +AV++ R +E+++ + + +E+
Sbjct: 1571 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1630
Query: 243 LAPGMALGSGR---RLVSEKASIFEKALA---SEKSPTADAKPAPKRATASEQPLAQ 293
L + RL +E+ + +K+LA +EK + A +R A EQ + Q
Sbjct: 1631 LERWQLKANEALRLRLQAEEVA-QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1686
Score = 48.1 bits (113), Expect = 2e-05
Identities = 110/496 (22%), Positives = 194/496 (39%), Gaps = 66/496 (13%)
Query: 13 SLARQRTLEDEEEQERERRR---------RHRNLSSTTDDEAPRLSQNGDRQASASER-- 61
SLA+ + +EE ERE RR R R L+ ++ +L++ +Q A+E+
Sbjct: 1656 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQEL 1715
Query: 62 ---LPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEG 118
E+ E + L +E++ + R Q+RQ +EA A ++ +E
Sbjct: 1716 IRLRAETEQGEQQRQL------LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLA 1769
Query: 119 RNSLSPVQATQKPLVSKKELEIPPR--RRLSREQRGPWALEEESL---------VGREPE 167
+ + ++ SK+ LE R L+ E AL EE+ R+
Sbjct: 1770 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRA 1829
Query: 168 ERKKGVPEKSPVLEKSSMPKKTA----PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEK 223
E ++ + EK + +++ K A EK +++ + A ++ L E+ A K
Sbjct: 1830 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ-AAQHK 1888
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGS--GRRLVSE-----KASIFEKALASEKSPTAD 276
+ E+ + L K S SE G+ + RR V E KAS FEKA A + +
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKAS-FEKAAAGKAELELE 1947
Query: 277 AKPAPKRA--TASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVAS 334
A T + A+ A A +E+R R + SLA + + A+
Sbjct: 1948 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAA 2007
Query: 335 RLPPVTLQVKIPS-----KEEEADMSSPTQRTYSSSLKR--SSPRTISFRMKPKKENSET 387
L+ K+ + E + + Q ++ KR + + +F ++ K++ +
Sbjct: 2008 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2067
Query: 388 TLTRSASMKLPDNTVKLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEK 447
TL + S+ ++L A RR+ E A S+R + E
Sbjct: 2068 TLQQEQSVL---------DQLRGEAEAARRAAEEAEEARVQAEREAA----QSRRQVEEA 2114
Query: 448 ELAGQSRAEPASSRKE 463
E QS E A +R +
Sbjct: 2115 ERLKQSAEEQAQARAQ 2130
Score = 43.5 bits (101), Expect = 5e-04
Identities = 54/217 (24%), Positives = 94/217 (43%), Gaps = 24/217 (11%)
Query: 15 ARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPL 74
ARQR L EEE+ R S ++EA R +R ++EE E K
Sbjct: 1970 ARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------------QRKAALEEVERLK-- 2015
Query: 75 PPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVS 134
+K E+ LR R E+ RQ ++ AQ Q+RL+AEE ++ + VQ ++ L
Sbjct: 2016 ---AKVEE---ARRLRERAEQESARQ-LQLAQEAAQKRLQAEEKAHAFA-VQQKEQELQQ 2067
Query: 135 KKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKS 194
+ E +L E EE+ R ER+ + +E++ K++A E++
Sbjct: 2068 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ--VEEAERLKQSAEEQA 2125
Query: 195 LVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKS 231
+ + + L E + + A +E+ +K++
Sbjct: 2126 QARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2162
Score = 36.2 bits (82), Expect = 0.074
Identities = 82/388 (21%), Positives = 151/388 (38%), Gaps = 53/388 (13%)
Query: 17 QRTLEDEE------EQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEV 70
+R+L++E +E ERR + + + +EA R + +A+ + RL E
Sbjct: 1593 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE--- 1649
Query: 71 PKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK 130
E Q++ + +A +E E E R + QA ++
Sbjct: 1650 -----------------------EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1686
Query: 131 PLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTA 190
++++ELE ++R E L E + R E ++G ++ + E+ + ++
Sbjct: 1687 RELAEQELE---KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR-- 1741
Query: 191 PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALG 250
E + + K E LA + + E + S+ R E +S EK+ ++ A G
Sbjct: 1742 -EAAAATQKRQELEAELAKVRAEM-EVLLASKARAEEESRSTSEKSKQRLEAEA-----G 1794
Query: 251 SGRRLVSEKASIFEKALASE-KSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQR 309
R L E A + +ALA E K A+ R A + + E A+ G K +
Sbjct: 1795 RFRELAEEAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEA 1852
Query: 310 GRALPGKNLPS-LAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKR 368
AL K + ++ A D RL Q K +E A + ++ S L+R
Sbjct: 1853 EIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL----RKASDSELER 1908
Query: 369 SSPRTISFRMKPKKENSETTLTRSASMK 396
+ ++ +++ E L AS +
Sbjct: 1909 QK-GLVEDTLRQRRQVEEEILALKASFE 1935
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 50.8 bits (120), Expect = 3e-06
Identities = 71/297 (23%), Positives = 137/297 (46%), Gaps = 33/297 (11%)
Query: 16 RQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASER--LPSVEEAEVPKP 73
R+ D ++Q+R + + L +++ E Q RQA A+ER L EE V +
Sbjct: 1372 REEAAVDAQQQKRSIQEELQQLRQSSEAEI----QAKARQAEAAERSRLRIEEEIRVVRL 1427
Query: 74 LPPASKDE----DEDIQSI-LRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQAT 128
A++ + + ++Q++ R + Q+RQ E A+ ++ +++ E R + V+
Sbjct: 1428 QLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER-LRRQVQDESQRKRQAEVE-- 1484
Query: 129 QKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEER-KKGVPEKSPVLEKSSMPK 187
L S+ + E R +QR ALEE L E E R ++ E++ ++ +
Sbjct: 1485 ---LASRVKAEAEAARE---KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1538
Query: 188 KTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTS-----VSEKS 242
+ + E L S + S +EK E++ E +AV++ R +E+++ + + +E+
Sbjct: 1539 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1598
Query: 243 LAPGMALGSGR---RLVSEKASIFEKALA---SEKSPTADAKPAPKRATASEQPLAQ 293
L + RL +E+ + +K+LA +EK + A +R A EQ + Q
Sbjct: 1599 LERWQLKANEALRLRLQAEEVA-QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1654
Score = 48.1 bits (113), Expect = 2e-05
Identities = 110/496 (22%), Positives = 194/496 (39%), Gaps = 66/496 (13%)
Query: 13 SLARQRTLEDEEEQERERRR---------RHRNLSSTTDDEAPRLSQNGDRQASASER-- 61
SLA+ + +EE ERE RR R R L+ ++ +L++ +Q A+E+
Sbjct: 1624 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQEL 1683
Query: 62 ---LPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEG 118
E+ E + L +E++ + R Q+RQ +EA A ++ +E
Sbjct: 1684 IRLRAETEQGEQQRQL------LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLA 1737
Query: 119 RNSLSPVQATQKPLVSKKELEIPPR--RRLSREQRGPWALEEESL---------VGREPE 167
+ + ++ SK+ LE R L+ E AL EE+ R+
Sbjct: 1738 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRA 1797
Query: 168 ERKKGVPEKSPVLEKSSMPKKTA----PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEK 223
E ++ + EK + +++ K A EK +++ + A ++ L E+ A K
Sbjct: 1798 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ-AAQHK 1856
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGS--GRRLVSE-----KASIFEKALASEKSPTAD 276
+ E+ + L K S SE G+ + RR V E KAS FEKA A + +
Sbjct: 1857 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKAS-FEKAAAGKAELELE 1915
Query: 277 AKPAPKRA--TASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVAS 334
A T + A+ A A +E+R R + SLA + + A+
Sbjct: 1916 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAA 1975
Query: 335 RLPPVTLQVKIPS-----KEEEADMSSPTQRTYSSSLKR--SSPRTISFRMKPKKENSET 387
L+ K+ + E + + Q ++ KR + + +F ++ K++ +
Sbjct: 1976 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2035
Query: 388 TLTRSASMKLPDNTVKLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEK 447
TL + S+ ++L A RR+ E A S+R + E
Sbjct: 2036 TLQQEQSVL---------DQLRGEAEAARRAAEEAEEARVQAEREAA----QSRRQVEEA 2082
Query: 448 ELAGQSRAEPASSRKE 463
E QS E A +R +
Sbjct: 2083 ERLKQSAEEQAQARAQ 2098
Score = 43.5 bits (101), Expect = 5e-04
Identities = 54/217 (24%), Positives = 94/217 (43%), Gaps = 24/217 (11%)
Query: 15 ARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPL 74
ARQR L EEE+ R S ++EA R +R ++EE E K
Sbjct: 1938 ARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------------QRKAALEEVERLK-- 1983
Query: 75 PPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVS 134
+K E+ LR R E+ RQ ++ AQ Q+RL+AEE ++ + VQ ++ L
Sbjct: 1984 ---AKVEE---ARRLRERAEQESARQ-LQLAQEAAQKRLQAEEKAHAFA-VQQKEQELQQ 2035
Query: 135 KKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKS 194
+ E +L E EE+ R ER+ + +E++ K++A E++
Sbjct: 2036 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ--VEEAERLKQSAEEQA 2093
Query: 195 LVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKS 231
+ + + L E + + A +E+ +K++
Sbjct: 2094 QARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2130
Score = 36.2 bits (82), Expect = 0.074
Identities = 82/388 (21%), Positives = 151/388 (38%), Gaps = 53/388 (13%)
Query: 17 QRTLEDEE------EQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEV 70
+R+L++E +E ERR + + + +EA R + +A+ + RL E
Sbjct: 1561 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE--- 1617
Query: 71 PKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK 130
E Q++ + +A +E E E R + QA ++
Sbjct: 1618 -----------------------EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1654
Query: 131 PLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTA 190
++++ELE ++R E L E + R E ++G ++ + E+ + ++
Sbjct: 1655 RELAEQELE---KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR-- 1709
Query: 191 PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALG 250
E + + K E LA + + E + S+ R E +S EK+ ++ A G
Sbjct: 1710 -EAAAATQKRQELEAELAKVRAEM-EVLLASKARAEEESRSTSEKSKQRLEAEA-----G 1762
Query: 251 SGRRLVSEKASIFEKALASE-KSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQR 309
R L E A + +ALA E K A+ R A + + E A+ G K +
Sbjct: 1763 RFRELAEEAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEA 1820
Query: 310 GRALPGKNLPS-LAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKR 368
AL K + ++ A D RL Q K +E A + ++ S L+R
Sbjct: 1821 EIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL----RKASDSELER 1876
Query: 369 SSPRTISFRMKPKKENSETTLTRSASMK 396
+ ++ +++ E L AS +
Sbjct: 1877 QK-GLVEDTLRQRRQVEEEILALKASFE 1903
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 50.8 bits (120), Expect = 3e-06
Identities = 71/297 (23%), Positives = 137/297 (46%), Gaps = 33/297 (11%)
Query: 16 RQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASER--LPSVEEAEVPKP 73
R+ D ++Q+R + + L +++ E Q RQA A+ER L EE V +
Sbjct: 1541 REEAAVDAQQQKRSIQEELQQLRQSSEAEI----QAKARQAEAAERSRLRIEEEIRVVRL 1596
Query: 74 LPPASKDE----DEDIQSI-LRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQAT 128
A++ + + ++Q++ R + Q+RQ E A+ ++ +++ E R + V+
Sbjct: 1597 QLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER-LRRQVQDESQRKRQAEVE-- 1653
Query: 129 QKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEER-KKGVPEKSPVLEKSSMPK 187
L S+ + E R +QR ALEE L E E R ++ E++ ++ +
Sbjct: 1654 ---LASRVKAEAEAARE---KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1707
Query: 188 KTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTS-----VSEKS 242
+ + E L S + S +EK E++ E +AV++ R +E+++ + + +E+
Sbjct: 1708 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1767
Query: 243 LAPGMALGSGR---RLVSEKASIFEKALA---SEKSPTADAKPAPKRATASEQPLAQ 293
L + RL +E+ + +K+LA +EK + A +R A EQ + Q
Sbjct: 1768 LERWQLKANEALRLRLQAEEVA-QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1823
Score = 48.1 bits (113), Expect = 2e-05
Identities = 110/496 (22%), Positives = 194/496 (39%), Gaps = 66/496 (13%)
Query: 13 SLARQRTLEDEEEQERERRR---------RHRNLSSTTDDEAPRLSQNGDRQASASER-- 61
SLA+ + +EE ERE RR R R L+ ++ +L++ +Q A+E+
Sbjct: 1793 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQEL 1852
Query: 62 ---LPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEG 118
E+ E + L +E++ + R Q+RQ +EA A ++ +E
Sbjct: 1853 IRLRAETEQGEQQRQL------LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLA 1906
Query: 119 RNSLSPVQATQKPLVSKKELEIPPR--RRLSREQRGPWALEEESL---------VGREPE 167
+ + ++ SK+ LE R L+ E AL EE+ R+
Sbjct: 1907 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRA 1966
Query: 168 ERKKGVPEKSPVLEKSSMPKKTA----PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEK 223
E ++ + EK + +++ K A EK +++ + A ++ L E+ A K
Sbjct: 1967 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ-AAQHK 2025
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGS--GRRLVSE-----KASIFEKALASEKSPTAD 276
+ E+ + L K S SE G+ + RR V E KAS FEKA A + +
Sbjct: 2026 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKAS-FEKAAAGKAELELE 2084
Query: 277 AKPAPKRA--TASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVAS 334
A T + A+ A A +E+R R + SLA + + A+
Sbjct: 2085 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAA 2144
Query: 335 RLPPVTLQVKIPS-----KEEEADMSSPTQRTYSSSLKR--SSPRTISFRMKPKKENSET 387
L+ K+ + E + + Q ++ KR + + +F ++ K++ +
Sbjct: 2145 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2204
Query: 388 TLTRSASMKLPDNTVKLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEK 447
TL + S+ ++L A RR+ E A S+R + E
Sbjct: 2205 TLQQEQSVL---------DQLRGEAEAARRAAEEAEEARVQAEREAA----QSRRQVEEA 2251
Query: 448 ELAGQSRAEPASSRKE 463
E QS E A +R +
Sbjct: 2252 ERLKQSAEEQAQARAQ 2267
Score = 43.5 bits (101), Expect = 5e-04
Identities = 54/217 (24%), Positives = 94/217 (43%), Gaps = 24/217 (11%)
Query: 15 ARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPL 74
ARQR L EEE+ R S ++EA R +R ++EE E K
Sbjct: 2107 ARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------------QRKAALEEVERLK-- 2152
Query: 75 PPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVS 134
+K E+ LR R E+ RQ ++ AQ Q+RL+AEE ++ + VQ ++ L
Sbjct: 2153 ---AKVEE---ARRLRERAEQESARQ-LQLAQEAAQKRLQAEEKAHAFA-VQQKEQELQQ 2204
Query: 135 KKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKS 194
+ E +L E EE+ R ER+ + +E++ K++A E++
Sbjct: 2205 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ--VEEAERLKQSAEEQA 2262
Query: 195 LVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKS 231
+ + + L E + + A +E+ +K++
Sbjct: 2263 QARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2299
Score = 36.2 bits (82), Expect = 0.074
Identities = 82/388 (21%), Positives = 151/388 (38%), Gaps = 53/388 (13%)
Query: 17 QRTLEDEE------EQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEV 70
+R+L++E +E ERR + + + +EA R + +A+ + RL E
Sbjct: 1730 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE--- 1786
Query: 71 PKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK 130
E Q++ + +A +E E E R + QA ++
Sbjct: 1787 -----------------------EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1823
Query: 131 PLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTA 190
++++ELE ++R E L E + R E ++G ++ + E+ + ++
Sbjct: 1824 RELAEQELE---KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR-- 1878
Query: 191 PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALG 250
E + + K E LA + + E + S+ R E +S EK+ ++ A G
Sbjct: 1879 -EAAAATQKRQELEAELAKVRAEM-EVLLASKARAEEESRSTSEKSKQRLEAEA-----G 1931
Query: 251 SGRRLVSEKASIFEKALASE-KSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQR 309
R L E A + +ALA E K A+ R A + + E A+ G K +
Sbjct: 1932 RFRELAEEAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEA 1989
Query: 310 GRALPGKNLPS-LAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKR 368
AL K + ++ A D RL Q K +E A + ++ S L+R
Sbjct: 1990 EIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL----RKASDSELER 2045
Query: 369 SSPRTISFRMKPKKENSETTLTRSASMK 396
+ ++ +++ E L AS +
Sbjct: 2046 QK-GLVEDTLRQRRQVEEEILALKASFE 2072
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 50.8 bits (120), Expect = 3e-06
Identities = 71/297 (23%), Positives = 137/297 (46%), Gaps = 33/297 (11%)
Query: 16 RQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASER--LPSVEEAEVPKP 73
R+ D ++Q+R + + L +++ E Q RQA A+ER L EE V +
Sbjct: 1382 REEAAVDAQQQKRSIQEELQQLRQSSEAEI----QAKARQAEAAERSRLRIEEEIRVVRL 1437
Query: 74 LPPASKDE----DEDIQSI-LRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQAT 128
A++ + + ++Q++ R + Q+RQ E A+ ++ +++ E R + V+
Sbjct: 1438 QLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER-LRRQVQDESQRKRQAEVE-- 1494
Query: 129 QKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEER-KKGVPEKSPVLEKSSMPK 187
L S+ + E R +QR ALEE L E E R ++ E++ ++ +
Sbjct: 1495 ---LASRVKAEAEAARE---KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1548
Query: 188 KTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTS-----VSEKS 242
+ + E L S + S +EK E++ E +AV++ R +E+++ + + +E+
Sbjct: 1549 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1608
Query: 243 LAPGMALGSGR---RLVSEKASIFEKALA---SEKSPTADAKPAPKRATASEQPLAQ 293
L + RL +E+ + +K+LA +EK + A +R A EQ + Q
Sbjct: 1609 LERWQLKANEALRLRLQAEEVA-QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1664
Score = 48.1 bits (113), Expect = 2e-05
Identities = 110/496 (22%), Positives = 194/496 (39%), Gaps = 66/496 (13%)
Query: 13 SLARQRTLEDEEEQERERRR---------RHRNLSSTTDDEAPRLSQNGDRQASASER-- 61
SLA+ + +EE ERE RR R R L+ ++ +L++ +Q A+E+
Sbjct: 1634 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQEL 1693
Query: 62 ---LPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEG 118
E+ E + L +E++ + R Q+RQ +EA A ++ +E
Sbjct: 1694 IRLRAETEQGEQQRQL------LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLA 1747
Query: 119 RNSLSPVQATQKPLVSKKELEIPPR--RRLSREQRGPWALEEESL---------VGREPE 167
+ + ++ SK+ LE R L+ E AL EE+ R+
Sbjct: 1748 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRA 1807
Query: 168 ERKKGVPEKSPVLEKSSMPKKTA----PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEK 223
E ++ + EK + +++ K A EK +++ + A ++ L E+ A K
Sbjct: 1808 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ-AAQHK 1866
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGS--GRRLVSE-----KASIFEKALASEKSPTAD 276
+ E+ + L K S SE G+ + RR V E KAS FEKA A + +
Sbjct: 1867 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKAS-FEKAAAGKAELELE 1925
Query: 277 AKPAPKRA--TASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVAS 334
A T + A+ A A +E+R R + SLA + + A+
Sbjct: 1926 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAA 1985
Query: 335 RLPPVTLQVKIPS-----KEEEADMSSPTQRTYSSSLKR--SSPRTISFRMKPKKENSET 387
L+ K+ + E + + Q ++ KR + + +F ++ K++ +
Sbjct: 1986 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2045
Query: 388 TLTRSASMKLPDNTVKLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEK 447
TL + S+ ++L A RR+ E A S+R + E
Sbjct: 2046 TLQQEQSVL---------DQLRGEAEAARRAAEEAEEARVQAEREAA----QSRRQVEEA 2092
Query: 448 ELAGQSRAEPASSRKE 463
E QS E A +R +
Sbjct: 2093 ERLKQSAEEQAQARAQ 2108
Score = 43.5 bits (101), Expect = 5e-04
Identities = 54/217 (24%), Positives = 94/217 (43%), Gaps = 24/217 (11%)
Query: 15 ARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPL 74
ARQR L EEE+ R S ++EA R +R ++EE E K
Sbjct: 1948 ARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------------QRKAALEEVERLK-- 1993
Query: 75 PPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVS 134
+K E+ LR R E+ RQ ++ AQ Q+RL+AEE ++ + VQ ++ L
Sbjct: 1994 ---AKVEE---ARRLRERAEQESARQ-LQLAQEAAQKRLQAEEKAHAFA-VQQKEQELQQ 2045
Query: 135 KKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKS 194
+ E +L E EE+ R ER+ + +E++ K++A E++
Sbjct: 2046 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ--VEEAERLKQSAEEQA 2103
Query: 195 LVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKS 231
+ + + L E + + A +E+ +K++
Sbjct: 2104 QARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2140
Score = 36.2 bits (82), Expect = 0.074
Identities = 82/388 (21%), Positives = 151/388 (38%), Gaps = 53/388 (13%)
Query: 17 QRTLEDEE------EQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEV 70
+R+L++E +E ERR + + + +EA R + +A+ + RL E
Sbjct: 1571 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE--- 1627
Query: 71 PKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK 130
E Q++ + +A +E E E R + QA ++
Sbjct: 1628 -----------------------EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1664
Query: 131 PLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTA 190
++++ELE ++R E L E + R E ++G ++ + E+ + ++
Sbjct: 1665 RELAEQELE---KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR-- 1719
Query: 191 PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALG 250
E + + K E LA + + E + S+ R E +S EK+ ++ A G
Sbjct: 1720 -EAAAATQKRQELEAELAKVRAEM-EVLLASKARAEEESRSTSEKSKQRLEAEA-----G 1772
Query: 251 SGRRLVSEKASIFEKALASE-KSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQR 309
R L E A + +ALA E K A+ R A + + E A+ G K +
Sbjct: 1773 RFRELAEEAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEA 1830
Query: 310 GRALPGKNLPS-LAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKR 368
AL K + ++ A D RL Q K +E A + ++ S L+R
Sbjct: 1831 EIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL----RKASDSELER 1886
Query: 369 SSPRTISFRMKPKKENSETTLTRSASMK 396
+ ++ +++ E L AS +
Sbjct: 1887 QK-GLVEDTLRQRRQVEEEILALKASFE 1913
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 50.8 bits (120), Expect = 3e-06
Identities = 71/297 (23%), Positives = 137/297 (46%), Gaps = 33/297 (11%)
Query: 16 RQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASER--LPSVEEAEVPKP 73
R+ D ++Q+R + + L +++ E Q RQA A+ER L EE V +
Sbjct: 1390 REEAAVDAQQQKRSIQEELQQLRQSSEAEI----QAKARQAEAAERSRLRIEEEIRVVRL 1445
Query: 74 LPPASKDE----DEDIQSI-LRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQAT 128
A++ + + ++Q++ R + Q+RQ E A+ ++ +++ E R + V+
Sbjct: 1446 QLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER-LRRQVQDESQRKRQAEVE-- 1502
Query: 129 QKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEER-KKGVPEKSPVLEKSSMPK 187
L S+ + E R +QR ALEE L E E R ++ E++ ++ +
Sbjct: 1503 ---LASRVKAEAEAARE---KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1556
Query: 188 KTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTS-----VSEKS 242
+ + E L S + S +EK E++ E +AV++ R +E+++ + + +E+
Sbjct: 1557 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1616
Query: 243 LAPGMALGSGR---RLVSEKASIFEKALA---SEKSPTADAKPAPKRATASEQPLAQ 293
L + RL +E+ + +K+LA +EK + A +R A EQ + Q
Sbjct: 1617 LERWQLKANEALRLRLQAEEVA-QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1672
Score = 48.1 bits (113), Expect = 2e-05
Identities = 110/496 (22%), Positives = 194/496 (39%), Gaps = 66/496 (13%)
Query: 13 SLARQRTLEDEEEQERERRR---------RHRNLSSTTDDEAPRLSQNGDRQASASER-- 61
SLA+ + +EE ERE RR R R L+ ++ +L++ +Q A+E+
Sbjct: 1642 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQEL 1701
Query: 62 ---LPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEG 118
E+ E + L +E++ + R Q+RQ +EA A ++ +E
Sbjct: 1702 IRLRAETEQGEQQRQL------LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLA 1755
Query: 119 RNSLSPVQATQKPLVSKKELEIPPR--RRLSREQRGPWALEEESL---------VGREPE 167
+ + ++ SK+ LE R L+ E AL EE+ R+
Sbjct: 1756 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRA 1815
Query: 168 ERKKGVPEKSPVLEKSSMPKKTA----PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEK 223
E ++ + EK + +++ K A EK +++ + A ++ L E+ A K
Sbjct: 1816 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ-AAQHK 1874
Query: 224 RNSSEKKSVLEKTSVSEKSLAPGMALGS--GRRLVSE-----KASIFEKALASEKSPTAD 276
+ E+ + L K S SE G+ + RR V E KAS FEKA A + +
Sbjct: 1875 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKAS-FEKAAAGKAELELE 1933
Query: 277 AKPAPKRA--TASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVAS 334
A T + A+ A A +E+R R + SLA + + A+
Sbjct: 1934 LGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAA 1993
Query: 335 RLPPVTLQVKIPS-----KEEEADMSSPTQRTYSSSLKR--SSPRTISFRMKPKKENSET 387
L+ K+ + E + + Q ++ KR + + +F ++ K++ +
Sbjct: 1994 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2053
Query: 388 TLTRSASMKLPDNTVKLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEK 447
TL + S+ ++L A RR+ E A S+R + E
Sbjct: 2054 TLQQEQSVL---------DQLRGEAEAARRAAEEAEEARVQAEREAA----QSRRQVEEA 2100
Query: 448 ELAGQSRAEPASSRKE 463
E QS E A +R +
Sbjct: 2101 ERLKQSAEEQAQARAQ 2116
Score = 43.5 bits (101), Expect = 5e-04
Identities = 54/217 (24%), Positives = 94/217 (43%), Gaps = 24/217 (11%)
Query: 15 ARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPL 74
ARQR L EEE+ R S ++EA R +R ++EE E K
Sbjct: 1956 ARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------------QRKAALEEVERLK-- 2001
Query: 75 PPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVS 134
+K E+ LR R E+ RQ ++ AQ Q+RL+AEE ++ + VQ ++ L
Sbjct: 2002 ---AKVEE---ARRLRERAEQESARQ-LQLAQEAAQKRLQAEEKAHAFA-VQQKEQELQQ 2053
Query: 135 KKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKS 194
+ E +L E EE+ R ER+ + +E++ K++A E++
Sbjct: 2054 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ--VEEAERLKQSAEEQA 2111
Query: 195 LVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKS 231
+ + + L E + + A +E+ +K++
Sbjct: 2112 QARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2148
Score = 36.2 bits (82), Expect = 0.074
Identities = 82/388 (21%), Positives = 151/388 (38%), Gaps = 53/388 (13%)
Query: 17 QRTLEDEE------EQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEV 70
+R+L++E +E ERR + + + +EA R + +A+ + RL E
Sbjct: 1579 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE--- 1635
Query: 71 PKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQK 130
E Q++ + +A +E E E R + QA ++
Sbjct: 1636 -----------------------EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1672
Query: 131 PLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTA 190
++++ELE ++R E L E + R E ++G ++ + E+ + ++
Sbjct: 1673 RELAEQELE---KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR-- 1727
Query: 191 PEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALG 250
E + + K E LA + + E + S+ R E +S EK+ ++ A G
Sbjct: 1728 -EAAAATQKRQELEAELAKVRAEM-EVLLASKARAEEESRSTSEKSKQRLEAEA-----G 1780
Query: 251 SGRRLVSEKASIFEKALASE-KSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQR 309
R L E A + +ALA E K A+ R A + + E A+ G K +
Sbjct: 1781 RFRELAEEAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEA 1838
Query: 310 GRALPGKNLPS-LAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKR 368
AL K + ++ A D RL Q K +E A + ++ S L+R
Sbjct: 1839 EIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL----RKASDSELER 1894
Query: 369 SSPRTISFRMKPKKENSETTLTRSASMK 396
+ ++ +++ E L AS +
Sbjct: 1895 QK-GLVEDTLRQRRQVEEEILALKASFE 1921
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.120 0.315
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,221,651
Number of Sequences: 37866
Number of extensions: 1034475
Number of successful extensions: 8610
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 904
Number of HSP's that attempted gapping in prelim test: 6104
Number of HSP's gapped (non-prelim): 2520
length of query: 517
length of database: 18,247,518
effective HSP length: 107
effective length of query: 410
effective length of database: 14,195,856
effective search space: 5820300960
effective search space used: 5820300960
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.